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We encourage you to perform a real-time search of NLEBeta
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1

Accommodation Holiday Inn Express & Suites  

E-Print Network [OSTI]

, COOPERATIVE EXTENSION SERVICE, UNIVERSITY OF FLORIDA, IFAS, FLORIDA A&M UNIVERSITY, COOPERATIVE EXTENSION PROGRAM, AND BOARDS OF COUNTY COMMISSIONERS COOPERATING. Institute of Food and Agricultural Sciences Range Opening Remarks - Henry Kempfer Kempfer Cattle Company & President Elect, Florida Cattlemen's Association

Florida, University of

2

August 18-19, 2011 Based out of the Holiday Inn Express--Concordia, Kansas  

E-Print Network [OSTI]

Farms (Lunch) Clay Center Utilities Director Riverscreen, Inc. 3:30 Milford Fish Hatchery 5:45 Return vegetarian meals Summer Tour Registration To pay by credit card, please register on-line at www.4-states Submission 2175 Lincoln Street, US 81 Concordia, KS 66901 785-243-2700 Reserve your room by July 31

Farritor, Shane

3

Biosecurity Programme Board Birmingham Holiday Inn  

E-Print Network [OSTI]

. Private sector concerns re acute oak decline Action (completed): Stewart Snape would circulate details (Timber Packaging and Pallet Confederation. Summary of Action points Agenda Item Action 3. Matters arising re item 6 on restocking after SPHNs. Action: Roger Coppock to liaise with legal colleagues and set

4

Holiday Foods.  

E-Print Network [OSTI]

28 28 2 2trJ 29 29 2" ~ .____./ 30 30 30 30 30 HOLIDAY FOODS Frances L. Reasonover and Mary K. Sweeten* The flavor , color, temperature and texture of foods enhance holiday occasions. However, in addition to attractiveness and taste... and almond extract. Serves 75 to 100. APRICOT PUNCH 2 large cans of apricots put through a sieve, or 2 large cans apricot nectar 4 cups orange juice 2 cups lemon juice 1 quart ginger ale 1 1/2 gallons lime or orange sherbet Sweetener may be added...

Reasonover, Frances L.; Sweeten, Mary K.

1981-01-01T23:59:59.000Z

5

The Committee convened in the Clark Room, Holiday Inn Capitol,  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* * *-

6

Holiday Food Drive  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuidedCH2MLLC History PublicationsFood Drive Holiday Food

7

Holiday Gift Drive  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuidedCH2MLLC History PublicationsFood Drive Holiday FoodGift

8

Holiday Schedule Get ready for the holidays with the Planetarium's  

E-Print Network [OSTI]

This holiday season, we're collecting toys for Cook Children's Hospital. Please help us make, such as extra-solar planets orbiting distant stars," said Levent Gurdemir, the planetarium's director

Huang, Haiying

9

GovCon Holiday Soiree  

Broader source: Energy.gov [DOE]

The 6th Annual GovCon Holiday Soiree will be held at the Kennedy Center on Monday, December 8, from 5:30pm to 7:30pm. The event is expected to bring together more than 200 representatives of women-...

10

The Committee convened in the Clark Room of the Holiday Inn  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* * *- -

11

The Committee met in the Columbia Room at the Holiday Inn  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* * *-+

12

The Committee met in the Clark Room in the Holiday Inn Capitol,  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* - - -

13

The Committee met in the Clark Room in the Holiday Inn Capitol,  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* - -

14

The Committee met in the Clark Room of the Capitol Holiday Inn,  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* -

15

The Committee met in the Clark Room, Holiday Inn Capitol at 550  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-* -

16

The Committee met in the Columbia Room at the Holiday Inn Capitol,  

U.S. Energy Information Administration (EIA) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ <Information Administration (EIA) 10 MECS Survey Data9c :0.1 Housing Unit3.1.Texas-Louisiana-*

17

Helping make the holidays happier  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Bigfront.jpgcommunity200cellHeat TransferHelping Make The Holidays

18

Maximum Vacation Carryover Balance & Upcoming Holiday Shutdown...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

24, 2014 through Sunday, January 4, 2015 for the annual holiday shutdown. The Lab will resume normal business operations on Monday, January 5, 2015. As a reminder, December 24, 25,...

19

SEP Success Story: Solar Field Powers Historic Garden Holiday...  

Energy Savers [EERE]

SEP Success Story: Solar Field Powers Historic Garden Holiday Display SEP Success Story: Solar Field Powers Historic Garden Holiday Display December 21, 2011 - 1:26pm Addthis This...

20

EECBG Success Story: North Pole's Holiday Wish for an Energy...  

Broader source: Energy.gov (indexed) [DOE]

Pole's Holiday Wish for an Energy Efficient 2012 EECBG Success Story: North Pole's Holiday Wish for an Energy Efficient 2012 December 23, 2011 - 4:20pm Addthis The city of North...

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Holiday Gatherings Made Easy & Delicious from  

E-Print Network [OSTI]

Nut Apple Walnut Maine Blueberry Lemon Sour Cream Cranberry Pecan Pumpkin Chocolate Chip Banana or Cranberry Nut Cookies & Treats (by the dozen) 12.60 Decorated Holiday Sugar Cookies Decorated Gingerbread to Heat Meatballs 37.00 (Cranberry or Sweet & Sour) Ready to Heat Chicken Wings 53.00 (Buffalo, Honey

Thomas, Andrew

22

Inside this issue: Green Holiday Tips 2  

E-Print Network [OSTI]

Inside this issue: Message 1 Green Holiday Tips 2 Real vs. Fake Tree 3 Semester wrap up: Energy a record number of CFL bulbs being distributed in the living residences, had another great energy campaign such as compost bins, bird feeders, energy/water saving appliances, bikes or bus passes make great gifts! Make

Kidd, William S. F.

23

Sales Tax Holiday for Energy-Efficient Appliances  

Broader source: Energy.gov [DOE]

In November 2007, Maryland enacted legislation creating a sales and use tax "holiday" for certain energy-efficient appliances, beginning in 2011. Under the law, qualifying appliances purchased...

24

Leveraging Holidays and Other Events | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Network Driving Demand Peer Exchange Call Series: Leveraging Holidays and Other Events, Call Slides and Discussion Summary, November 7, 2013. Call Slides and Discussion Summary...

25

Happy Holidays from Clemson December 2006 Dear Friends and Family,  

E-Print Network [OSTI]

Happy Holidays from Clemson December 2006 Dear Friends and Family, Can it be that another year has a wonderful time enjoying the beautiful Lamar Valley. Mom, Dad and Shala also made a trip to Snowbird, UT

Childress, Michael J.

26

Sales Tax Holiday for Energy-Efficient Appliances  

Broader source: Energy.gov [DOE]

The state of Missouri offers consumers a seven-day ''exemption from state sales taxes'' on certain Energy Star certified new appliances. The state sales tax holiday, known as the "Show-Me Green...

27

Observed Holiday Aerosol Reduction and Temperature Cooling over East Asia  

SciTech Connect (OSTI)

The Spring Festival air pollution in China was investigated using the long-term observations from 2001-2012 over 323 stations. During the Spring Festival with nearly half of urban population leaving the cities for holidays, the particulate matter (PM10) concentration is about 24.5?gm-3 (23%) lower than normal days. Associated with the national-wide burning of firework, the PM10 concentration sharply increases to 123.8?gm-3 at Chinese New Year Day (increment of 35%). Similar to PM10, the SO2 and NO2 decrease from high values in normal days to a holiday minimum with reduction of 23.3% and 30.6%, respectively. The NO2 has no peak in New Year Day because of the different emission source. The night mean and minimum temperature co-vary with PM10. Both nighttime mean and minimum temperature decrease by about 2.1°C during the holidays. And in association with the pollution jump at New Year Day the night temperature simultaneously increase by about 0.89°C. The in-phase co-variations between PM10 and night temperature suggest an overall warming effect of holiday aerosol during winter in China.

Gong, Daoyi; Wang, Wenshan; Qian, Yun; Bai, Wenbing; Guo, Yuanxi; Mao, Rui

2014-06-16T23:59:59.000Z

28

University Fire Marshal's Office Holiday Fire Safety Information  

E-Print Network [OSTI]

festive space heaters... As you un-box those lights, wires and bearers of holiday warmth, it is also heaters. Now is the time--as you set them up--to ensure that you do so providing for the safety of your must be kept in water at all times to slow the natural drying process. Approved Tree Lots ­ Licensed

Straight, Aaron

29

Fountain Inn, South Carolina: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 NoPublicIDAPowerPlantSitingConstruction.pdfNotify98.pdf JumpFlixMapFileFostoria, Ohio: Energy Resources JumpInn,

30

Tax Information Publication -2014 New Energy Star and WaterSense Products Sales Tax Holiday 1 2014 Sales Tax Holiday for  

E-Print Network [OSTI]

, 2014. For a list of qualifying items, scan this QR code. Qualifying Energy Star Products · Air purifierTax Information Publication - 2014 New Energy Star and WaterSense Products Sales Tax Holiday 1 2014 Sales Tax Holiday for New Energy Star and WaterSense Products September 19 through September 21, 2014

Florida, University of

31

Energy Saving Holiday Kitchen Trivia | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehicles » AlternativeUpDrain-Water HeatElementsEnergyHoliday Kitchen

32

Holiday City South, New Jersey: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:GreerHi Gtel JumpHoard, Wisconsin:Holiday City South, New Jersey:

33

Holiday City-Berkeley, New Jersey: Energy Resources | Open Energy  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:GreerHi Gtel JumpHoard, Wisconsin:Holiday City South, New

34

LED Holiday Lights: Festive, Safe, and Efficient! | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensionalthe10 DOEWashington, DCKickoffLDV HVAC Model DevelopmentHoliday

35

Chancellor Blumenthal & his wife, Kelly Weisberg, cordially invite you to a Holiday Gathering & Campus Celebration  

E-Print Network [OSTI]

Chancellor Blumenthal & his wife, Kelly Weisberg, cordially invite you to a Holiday Gathering; UCSC Student #12;El Canciller Blumenthal y su esposa, Kelly Weisberg, lo invitan cordialmente

California at Santa Cruz, University of

36

Holiday Shopping and Electric Vehicles | GE Global Research  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuidedCH2MLLC History PublicationsFood Drive Holiday

37

Holiday Heights, New Jersey: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:GreerHi Gtel JumpHoard, Wisconsin:Holiday City South, New59512°,

38

LED Holiday Lights: Festive, Safe, and Efficient! | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensionalthe10 DOEWashington, DCKickoffLDV HVAC Model DevelopmentHolidayLED

39

Mythologies of an American everyday landscape : Henry Ford at the Wayside Inn  

E-Print Network [OSTI]

Ford purchased property in 1923 in Sudbury, Massachusetts in order to preserve an historic inn associated with the poet Henry Wadsworth Longfellow. Over the next twenty years, his mission expanded to create an idealized ...

Wortham, Brooke Danielle

2006-01-01T23:59:59.000Z

40

E-Print Network 3.0 - aln gan inn Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary: size. Introduction GaN and its alloys with InN and AlN have been used for optoelectronic devices... region. The formation of self-assembled GaN nanostructures on aluminum...

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

BAST `98 Workshop Program The Inn at the Tides, Bodega Bay, California  

E-Print Network [OSTI]

: Solomon W. Golomb, Univ. of Southern California #12;BAST `98 Workshop Program 3 The Inn at the Tides-Based Test Methodology, Sobhan Mukherji, Fujitsu 1.3 A Structured Test Methodology for Systems on Silicon

Stanford University

42

Electrical and optical properties of p-type InN  

E-Print Network [OSTI]

Electrical and optical properties of p-type InN Marie A.thermoelectric and electrical properties of Mg doped InNthe temperature dependent electrical properties, the sign of

Mayer, M.A.

2013-01-01T23:59:59.000Z

43

ARLINGTON/DEFOREST AREA CATERING INFORMATION  

E-Print Network [OSTI]

ARLINGTON/DEFOREST AREA CATERING INFORMATION Rude's Family Catering DeForest, WI 608-846-5959 (Debbie) Roadside Grill DeForest, WI 608-846-1874 (Pete) Piggly Wiggly Poynette, WI 608-635-2647 (Heidi INFORMATION Holiday Inn Express 7184 Morrisonville Rd. DeForest, WI 53532 608-846-8686 toll free 800-HOLIDAY

Balser, Teri C.

44

Happy Holidays from Boise State Transportation & Parking Services! Some information for the season  

E-Print Network [OSTI]

Happy Holidays from Boise State Transportation & Parking Services! Some information for the season, and accessories, visit http://rec.boisestate.edu/clc/, or call 426-RIDE (7433). Participate in the FREE Valley

Barrash, Warren

45

Memorial Day Weekend Sales Tax Holiday for Energy-Efficient Products  

Broader source: Energy.gov [DOE]

Purchases of certain energy-efficient products during Memorial Day weekend are exempt from the state sales and use tax.* This amounts to a three-day tax holiday beginning on the Saturday preceding...

46

Spectral dependence of third-order nonlinear optical properties in InN  

SciTech Connect (OSTI)

We report on the nonlinear optical properties of InN measured in a wide near-infrared spectral range with the femtosecond Z-scan technique. The above-bandgap nonlinear absorption in InN is found to originate from the saturation of absorption by the band-state-filling and its cross-section increases drastically near the bandgap energy. With below-bandgap excitation, the nonlinear absorption undergoes a transition from saturation absorption (SA) to reverse-SA (RSA), attributed to the competition between SA of band-tail states and two-photon-related RSA. The measured large nonlinear refractive index of the order of 10{sup ?10} cm{sup 2}/W indicates InN as a potential material for all-optical switching and related applications.

Ahn, H., E-mail: hyahn@mail.nctu.edu.tw; Lee, M.-T.; Chang, Y.-M. [Department of Photonics and Institute of Electro-Optical Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan (China)

2014-05-19T23:59:59.000Z

47

THz generation from InN films due to destructive interference between optical rectification and photocurrent surge  

E-Print Network [OSTI]

THz generation from InN films due to destructive interference between optical rectification.1088/0268-1242/25/1/015004 THz generation from InN films due to destructive interference between optical rectification investigated the characteristics of THz generation including the dependence of the output power

Gilchrist, James F.

48

Dendrochronology of the Wixson Road Log Cabin and Benjamin Patterson Inn, Corning-Painted Post Historical Society, Corning, NY  

E-Print Network [OSTI]

in 1838, 1855, and again in 1863. In the NYS Census for 1865, the house was described as "log Patterson Inn with its well- documented 1796 building date and the patterns of a modern oak chronology

Manning, Sturt

49

Ramp meters on trial: Evidence from the Twin Cities metering holiday  

E-Print Network [OSTI]

Ramp meters on trial: Evidence from the Twin Cities metering holiday David Levinson a,*, Lei Zhang; accepted 15 December 2004 Abstract Ramp meters in the Twin Cities have been the subject of a recent test metering for several representative freeways during the afternoon peak period. Seven performance measures

Levinson, David M.

50

Metallicity of InN and GaN surfaces exposed to NH{sub 3}.  

SciTech Connect (OSTI)

A systematic study of energies and structures of InN and GaN (0001) surfaces exposed to NH{sub 3} and its decomposition products was performed with first-principles methods. A phenomenological model including electron counting contributions is developed based on calculated DFT energies and is used to identify low-energy structures. These predictions are checked with additional DFT calculations. The equilibrium phase diagrams are found to contain structures that violate the electron counting rule. Densities of states for these structures indicate n-type conductivity, consistent with available experimental results.

Walkosz, W.; Zapol, P.; Stephenson, G. B. (Materials Science Division)

2012-01-01T23:59:59.000Z

51

Fundamental optical properties of InN grown by epitaxial lateral overgrowth method  

SciTech Connect (OSTI)

Optical properties of InN grown by the epitaxial lateral overgrowth (ELO) method have been studied using photoluminescence (PL) and excitation-correlation (EC) measurements. The PL spectrum is analyzed by free-electron recombination band (FERB) model, which shows that the ELO sample has a very low background carrier concentration (n=5.5*10{sup 16}[cm{sup ?3]}). EC measurements show that the dependences of the band gap renormalization and Auger effect on the carrier concentrations are similar in spite of the different physical origins.

Kametani, Tatsuma; Kamimura, Jumpei; Inose, Yuta; Kunugita, Hideyuki; Kikuchi, Akihiko; Kishino, Katsumi; Ema, Kazuhiro [Department of Engineering and Applied Science, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554 (Japan)

2013-12-04T23:59:59.000Z

52

Near-infrared InN quantum dots on high-In composition InGaN  

SciTech Connect (OSTI)

We report the growth of InN quantum dots (QDs) on thick InGaN layers with high In composition (>50%) by molecular beam epitaxy. Optimized growth conditions are identified for the InGaN layers at reduced growth temperature and increased active N flux resulting in minimized phase separation and defect generation. The InN QDs grown on top of the optimized InGaN layer exhibit small size, high density, and photoluminescence up to room temperature. The InN/InGaN QDs reveal excellent potential for intermediate band solar cells with the InGaN and InN QD bandgap energies tuned to the best match of absorption to the solar spectrum.

Soto Rodriguez, Paul E. D.; Gomez, Victor J.; Kumar, Praveen; Calleja, Enrique; Noetzel, Richard [Instituto de Sistemas Optoelectronicos y Microtecnologia (ISOM), Universidad Politecnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid (Spain)] [Instituto de Sistemas Optoelectronicos y Microtecnologia (ISOM), Universidad Politecnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid (Spain)

2013-04-01T23:59:59.000Z

53

ATLAS-Experiment Abbildung 48: Monte-Carlo-Simulation eines tt-Ereignisses in einem Layout fur den Inne-  

E-Print Network [OSTI]

ATLAS-Experiment Abbildung 48: Monte-Carlo-Simulation eines t¯t-Ereignisses in einem Layout f¨ur den Inne- ren Detektor des ATLAS-Experiments mit vier Lagen von Silizium-Pixeldetektoren und f¨unf Lagen von Silizium-Streifendetektoren. 82 #12;ATLAS-Experiment ATLAS-Experiment Gruppenleiter: M

54

Effect of Mg doping on the structural and free-charge carrier properties of InN films  

SciTech Connect (OSTI)

We present a comprehensive study of free-charge carrier and structural properties of two sets of InN films grown by molecular beam epitaxy and systematically doped with Mg from 1.0?×?10{sup 18}?cm{sup ?3} to 3.9?×?10{sup 21}?cm{sup ?3}. The free electron and hole concentration, mobility, and plasmon broadening parameters are determined by infrared spectroscopic ellipsometry. The lattice parameters, microstructure, and surface morphology are determined by high-resolution X-ray diffraction and atomic force microscopy. Consistent results on the free-charge carrier type are found in the two sets of InN films and it is inferred that p-type conductivity could be achieved for 1.0?×?10{sup 18}?cm{sup ?3}???[Mg]???9.0?×?10{sup 19}?cm{sup ?3}. The systematic change of free-charge carrier properties with Mg concentration is discussed in relation to the evolution of extended defect density and growth mode. A comparison between the structural characteristics and free electron concentrations in the films provides insights in the role of extended and point defects for the n-type conductivity in InN. It further allows to suggest pathways for achieving compensated InN material with relatively high electron mobility and low defect densities. The critical values of Mg concentration for which polarity inversion and formation of zinc-blende InN occurred are determined. Finally, the effect of Mg doping on the lattice parameters is established and different contributions to the strain in the films are discussed.

Xie, M.-Y.; Ben Sedrine, N.; Hung, L.; Monemar, B.; Darakchieva, V., E-mail: vanya@ifm.liu.se [Department of Physics, Chemistry, and Biology, IFM, Linköping University, SE-581 83 Linköping (Sweden); Schöche, S.; Hofmann, T.; Schubert, M. [Center for Nanohybrid Functional Materials, Department of Electrical Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0511 (United States); Wang, X. [State Key Laboratory of Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing (China); Yoshikawa, A. [Center for SMART Green Innovation Research, Chiba University, Chiba (Japan); Department of Information and Communication Engineering, Kogakuin University, Tokyo (Japan); Wang, K.; Araki, T. [Department of Photonics, Ritsumeikan University, 1-1-1 Noji Higashi, Kusatsu, Shiga 525-8577 (Japan); Nanishi, Y. [Department of Photonics, Ritsumeikan University, 1-1-1 Noji Higashi, Kusatsu, Shiga 525-8577 (Japan); WCU Hybrid Materials Program, Department of Materials Science and Engineering, Seoul National University, Seoul 151-744 (Korea, Republic of)

2014-04-28T23:59:59.000Z

55

Your Holidays ... Brought to You by Fuel Cells | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehiclesTankless or Demand-TypeWelcome toFarm GrowthHolidays ... Brought to

56

It's Finally Time to Think about the Holidays! | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists'Montana.ProgramJulietipDepartmentJuneWhen I think of wind technology,Using LED holiday

57

Dislocation reduction via selective-area growth of InN accompanied by lateral growth by rf-plasma-assisted molecular-beam epitaxy  

SciTech Connect (OSTI)

We investigated the selective-area growth (SAG) of InN by rf-plasma-assisted molecular-beam epitaxy using molybdenum (Mo)-mask-patterned sapphire (0001) substrates, which resulted in the formation of regularly arranged N-polar InN microcrystals. Transmission electron microscopy observation confirmed that the laterally grown side areas were nearly dislocation-free, although many threading dislocations (10{sup 9}-10{sup 10} cm{sup -2}) were generated at the InN/sapphire interface and propagated into the center of the InN microcrystals along the crystal c-axis. The laterally grown InN microcrystals exhibited narrow near-IR emission spectra with a peak photon energy of 0.627 eV and a linewidth of 39 meV at room temperature.

Kamimura, Jumpei [Department of Engineering and Applied Sciences, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554 (Japan); CREST, Japan Science and Technology Agency, Kawaguchi, Saitama 330-0012 (Japan); Kishino, Katsumi; Kikuchi, Akihiko [Department of Engineering and Applied Sciences, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554 (Japan); CREST, Japan Science and Technology Agency, Kawaguchi, Saitama 330-0012 (Japan); Sophia Nanotechnology Research Center, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554 (Japan)

2010-10-04T23:59:59.000Z

58

A4.2 Raman and IR studies of InN C. Wetzel and I. Akasaki  

E-Print Network [OSTI]

and reflection in the near infrared spectral region have been employed to study the fundamental bandgap, phononsN was an extrapolation of the Ga1-xInxN (0 x 1) alloy modes in reflection towards the binary compound [1]. A typically) in the infrared and must also be accounted for the broadened Reststrahlen band in pure InN films (e.g. in [1

Wetzel, Christian M.

59

2012 BATTERIES GORDON RESEARCH CONFERENCE, MARCH 4-9, 2012  

SciTech Connect (OSTI)

The Gordon Research Conference on BATTERIES was held at Four Points Sheraton / Holiday Inn Express, Ventura, California, March 4-9, 2012. The Conference was well-attended with 176 participants. Gordon Research Conferences does not permit publication of meeting proceedings.

Stephen Harris

2012-03-09T23:59:59.000Z

60

Macintosh HD:Users:z095994:Desktop:Exits:2013_LAHotel_Info.docx Hotel Info in Los Alamos  

E-Print Network [OSTI]

, NM 87544 505-672-3838 Holiday Inn Express at Entrada Park 60 Entrada Dr. Los Alamos, NM 87544 505Macintosh HD:Users:z095994:Desktop:Exits:2013_LAHotel_Info.docx Hotel Info in Los Alamos of hotels in Los Alamos: Adobe Pines Bed & Breakfast 2101 Loma Linda Dr. Los Alamos, NM 87544 505

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

postdoc:Postdoc Program:Career Fair:2013:2013_LAHotel_Info.doc Hotel Info in Los Alamos  

E-Print Network [OSTI]

-672-3838 Holiday Inn Express at Entrada Park 60 Entrada Dr. Los Alamos, NM 87544 505-661-2646 Motel 6 2175 Trinitypostdoc:Postdoc Program:Career Fair:2013:2013_LAHotel_Info.doc Hotel Info in Los Alamos of hotels in Los Alamos: Adobe Pines Bed & Breakfast 2101 Loma Linda Dr. Los Alamos, NM 87544 505

62

Hotel Info in Los Alamos There are many wonderful places to stay in Santa Fe as well as the surrounding  

E-Print Network [OSTI]

Alamos, NM 87544 505-672-3838 Holiday Inn Express at Entrada Park 60 Entrada Dr. Los Alamos, NM 87544 505Hotel Info in Los Alamos There are many wonderful places to stay in Santa Fe as well as the surrounding areas but the following is a list of hotels in Los Alamos: Adobe Pines Bed & Breakfast 2101 Loma

63

Enhancing structural transition by carrier and quantum confinement: Stabilization of cubic InN quantum dots by Mn incorporation  

SciTech Connect (OSTI)

We demonstrate in this work controllable synthesis of cubic InN nanocrystals through Mn doping. We show that the pristine nanocrystal has the wurtzite structure, but can be converted into the zinc-blende (ZB) structure when it is doped with Mn. Our first-principles calculations show that the phase transition is caused by the stronger p-d coupling between the host p valence state and the impurity d level in the ZB structure, which makes the hole generation in the ZB structure easier. Quantum confinement in the nanocrystals further enhanced this effect. This observation lays an important foundation for defects control of crystal phases.

Meng, Xiuqing; Wu, Fengmin [Zhejiang Normal University, Jinhua, Zhejiang Province 321004 (China)] [Zhejiang Normal University, Jinhua, Zhejiang Province 321004 (China); Chen, Zhanghui; Li, Shu-Shen [State Key Laboratory for Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China)] [State Key Laboratory for Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China); Chen, Zhuo [Department of Physics, Beijing Institute of Technology, Beijing 100081 (China)] [Department of Physics, Beijing Institute of Technology, Beijing 100081 (China); Li, Jingbo, E-mail: jbli@semi.ac.cn, E-mail: swei@nrel.gov [Zhejiang Normal University, Jinhua, Zhejiang Province 321004 (China) [Zhejiang Normal University, Jinhua, Zhejiang Province 321004 (China); State Key Laboratory for Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China); Wu, Junqiao [Department of Materials Science and Engineering, University of California, Berkeley, California 94720 (United States)] [Department of Materials Science and Engineering, University of California, Berkeley, California 94720 (United States); Wei, Su-Huai, E-mail: jbli@semi.ac.cn, E-mail: swei@nrel.gov [National Renewable Energy Laboratory, Golden, Colorado 80401 (United States)] [National Renewable Energy Laboratory, Golden, Colorado 80401 (United States)

2013-12-16T23:59:59.000Z

64

Train directions from Newark Airport to Nassau Inn or Palmer House Hotel Train is the most convenient way to get to Princeton from EWR. From the terminals at  

E-Print Network [OSTI]

Train directions from Newark Airport to Nassau Inn or Palmer House Hotel Train is the most), and proceed to track 5. You need the NorthEast Corridor (NEC) train to Trenton (not Long Branch). They go is valid for any train on this route. The ride takes 40-45 minutes, and you exit at Princeton Junction

65

The Mercer Clinic Holiday Pet Basket program was started in 1995 by Veterinary Medical Teaching Hospital staff members of the "VOICE" staff newsletter. It has grown due to need over the years from only 25 baskets to 130  

E-Print Network [OSTI]

The Mercer Clinic Holiday Pet Basket program was started in 1995 by Veterinary Medical Teaching that every year we rely on the kindness of others to help these very special pets who are more than a pet this wonderful tradition alive by contributing any time of year to the Mercer Veterinary Clinic Holiday Pet

Schladow, S. Geoffrey

66

The Hebrew University Center for Nanoscience and Nanotechnology  

E-Print Network [OSTI]

The Hebrew University Center for Nanoscience and Nanotechnology Annual Conference 2015 Holiday Inn your work during the Nanoscience and Nanotechnology Center Yearly Conference, which will be held

Simon, Emmanuel

67

Berkeley Lab Holiday Schedule  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth (AOD)ProductssondeadjustsondeadjustAboutScienceCareers Apply for a Job External ApplicantsSearch

68

NERSC Holiday Schedule  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Opticalhttp://www.fnal.gov/directorate/nalcal/nalcal02_07_05_files/nalcal.gif Directorate -

69

Post-Holiday Holiday Shopping | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists' Research | Department ofpermitPerformance9||Department of EnergyofFossil

70

LYAKllOVSKY. v .. ILeIlEv. A.. anJ AGNON. A. jI,tmklling "f JUl1lug~ and in.'tabilili~s ill rock mass by In~"ns of a nun-lin,Jj'I<'s-RaSiM5. South African tnsuunc of Mining and Mctalturgv. 200 I.  

E-Print Network [OSTI]

rock mass by In~"ns of a nun-linmrS/.\\' ",,,1 S"ismi,:iry in t;p , LYAKllOVSKY. v .. ILeIlEv. A.. anJ AGNON. A. jI,·tmklling "f JUl1lug~ and in.'tabilili~s ill' *(jeological Surrey of Israel, l erusatem Israel f/SS lntemauonat Limited, l,VelkOIl1, South A/rim i

Lyakhovsky, Vladimir

71

Expressive Language Profiles of Verbally Expressive Adolescents  

E-Print Network [OSTI]

Expressive Language Profiles of Verbally Expressive Adolescents and Young Adults With Down Syndrome of a subset of highly verbally expressive adolescents and young adults with Down syndrome (DS) and those differences in their expressive language profiles. KEY WORDS: Down syndrome, fragile X syndrome, narrative

Nguyen, Danh

72

2011 Holiday Take Home Menu Main Courses  

E-Print Network [OSTI]

For 3 Days in Maple, Smoked & Slow Roasted with Maple Butter, Served with Cranberry Marmalade Serves 6, Grilled Leeks with a Herb Butter _____ Small $15.00 Serves 3-4 _____ Large $28.00 Serves 5-8 Cranberry Braised Winter Greens Tender Greens cooked with fresh cranberry and honey _____ Small $15.00 Serves 3

Mathis, Wayne N.

73

Keep Foodborne Illness from Spoiling Holiday Parties  

E-Print Network [OSTI]

. ? After each cleaning, sanitize the countertops with a solution of 1 teaspoon bleach and 1 quart of water. Let the solution stand on the surface for a few minutes, then dry the countertops with a paper towel. ? If you are using cloth towels to wipe up.... Wash the cutting boards with hot, soapy water and then sanitize them after each use. ? Never place cooked food on a plate that has held raw meat, poultry, fish, or seafood unless the plate has been washed thoroughly with hot, soapy water. Cook food...

Nutrition, Food and

2008-12-17T23:59:59.000Z

74

Happy Holidays! Oldest and Large~t'  

E-Print Network [OSTI]

-bearing~tudent group accounts after Dean for Student Life Larry G. Benedict pledged to fund interest 'that would have." . Tracy F. Purinton, assistant dean for student activities, said that there are approximately eight.01) students Farhan I. Merali '05 and Corey A. Kemper G take notes on electronic tablets. Originally intended

75

happy holidays! FROM THE EXECUTIVE VICE PRESIDENT  

E-Print Network [OSTI]

's foremost coalition of leaders in sustainable building design and construction. · The Northwest Corner

Qian, Ning

76

Today LED Holiday Lights, Tomorrow the World?  

SciTech Connect (OSTI)

This article for The APEM Advantage, the quarterly newsletter of the Association of Professional Energy Managers (APEM) describes the recent increase in the popularity of light emitting diode (LED) lighting and compares LED light output with that of incandescent and compact fluorescent lighting.

Gordon, Kelly L.

2004-12-20T23:59:59.000Z

77

Code of Conduct Regarding Holiday Gifts  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series to User Group and Userof aChristinaCliffPublicationCode of Conduct

78

Michelle L. Holiday | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergyENERGYWomen OwnedofDepartment ofJared Temanson -ofMarc MorialMegan SlackDr. Michael

79

A Factsheet on Holiday Fire Prevention  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert SouthwestTechnologies |November 2011 Mon,ElectrocatalysisAssociativeElectrolytes forach

80

High expression Zymomonas promoters  

DOE Patents [OSTI]

Identified are mutants of the promoter of the Z. mobilis glyceraldehyde-3-phosphate dehydrogenase gene, which direct improved expression levels of operably linked heterologous nucleic acids. These are high expression promoters useful for expression of chimeric genes in Zymomonas, Zymobacter, and other related bacteria.

Viitanen, Paul V. (West Chester, PA); Tao, Luan (Havertown, PA); Zhang, Yuying (New Hope, PA); Caimi, Perry G. (Kennett Square, PA); McCole, Laura (East Fallowfield, PA): Zhang, Min (Lakewood, CO); Chou, Yat-Chen (Lakewood, CO); McCutchen, Carol M. (Wilmington, DE); Franden, Mary Ann (Centennial, CO)

2011-08-02T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Final Report  

SciTech Connect (OSTI)

This is the front matter for the 7th Biennial Symposium, International Society for Environmental Biotechnology, held at the Holiday Inn Chicago Mart Plaza, Chicago, Illinois on the dates of June 18-21, 2004. It contains a list of the symposium organizers, acknowledgements and the symposium overview.

Ananda M. Chakrabarty

2009-06-18T23:59:59.000Z

82

Express Licensing Program  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

License? PATENTS Non-Exclusive License Issue Fee 7,500 Annual License Fee 500 Earned Royalty on Sales 2% The fees associated with each patent offered through the Express...

83

Converting Nested Algebra Expressions into Flat Algebra Expressions  

E-Print Network [OSTI]

Converting Nested Algebra Expressions into Flat Algebra Expressions JAN PAREDAENS University of Antwerp and DIRK VAN GUCHT Indiana University Nested relations generalize ordinary flat relations by allowing tuple values to be either atomic or set valued. The nested algebra is a generalization of the flat

Van Gucht, Dirk

84

RockyMountainParkInn.com 888.465.4329  

E-Print Network [OSTI]

Opportunity Service Provider. Printed on Recycled Paper­70% Pre-consumer Waste, 30% Post-consumer waste vehicles is abundant and easy to navigate. And, the hotel caters to animal lovers with a variety of pet

Rutledge, Steven

85

[SKRIV INN FIRMANAVN] Peer-Reviewed Term Project  

E-Print Network [OSTI]

20 radiation energy received on a given surface21 area and recorded during a given time.22 23 Figure with December. The lines30 throughout the figure are lines of constant solar31 flux. The black areas represent periods of no32 solar insolation, which exist at the North Pole33 when you have polar nights in the winter

Russell, Lynn

86

I-N-N Electric Coop, Inc | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of InspectorConcentrating Solar Power BasicsGermany: EnergyPowerInformationHomerHydrogenEnergyN-N Electric

87

Sonoma Mission Inn Geothermal Area | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revisionEnvReviewNonInvasiveExplorationUT-g GrantAtlas (PACA Region -Sonelgaz Jump to: navigation,SonomaMission

88

Collective systems for creative expression  

E-Print Network [OSTI]

This thesis defines collective systems as a unique category of creative expression through the procedures of micro and macro cycles that address the transition from connectivity to collectivity. This thesis discusses the ...

Ar?kan, Harun Burak

2006-01-01T23:59:59.000Z

89

Sales Tax Holiday for Energy-Efficient Appliances  

Broader source: Energy.gov [DOE]

'''Note: Legislation enacted in June 2011 ([http://www.ncleg.net/enactedlegislation/sessionlaws/html/2011-2012/sl201... S.B. 267]) that removed geothermal heat pumps from the list of energy systems...

90

Keep Foodborne Illness from Spoiling Holiday Parties (Spanish)  

E-Print Network [OSTI]

alimentos que hayan estado a temperatura ambiente o que hayan sido tocados por manos que pudieran estar sucias. Recuerde, alimentos preparados y alimentos perecederos ? calientes o fr?os- que hayan permanecido a temperatura ambiente por m?s de dos... cacerola y coc?nela a fuego medio bajo. Remu?vala constantemente con un batidor hasta que la mezcla se vuelve espesa y apenas forma una capa sobre una cuchara. Use un term?metro para alimentos para asegurar que la mezcla de huevos y leche alcanza 160...

Nutrition, Food and

2008-12-17T23:59:59.000Z

91

EM Waste Isolation Pilot Plant Team's Holiday Spirit Shines | Department  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists'Montana.Program - LibbyofThisStatement ||More Emphasis onEnergy One Systemof

92

Save Energy on Appliances this Holiday Season | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehicles »ExchangeDepartmentResolve to Save EnergySandia Cooler

93

Fuel Cell Powers Up Festivities at Secretary Chu's Holiday Party |  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensional ElectricalEnergy Frozen TelescopeRenewable and Waste

94

Holiday Gifts for Energy Efficiency | Department of Energy  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of Energy Power.pdf11-161-LNG | Department ofHTS Cable ProjectsHistory History On January 7, 2011,

95

SEP Success Story: Solar Field Powers Historic Garden Holiday Display |  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartment of Energy fromCommentsRevolving Loan FundsDepartment ofNO.FEVery Far

96

Save Money with LED Holiday Light Strings | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartment of Energy fromCommentsRevolving STATEMENTSavannah River Site SavannahSave

97

Tips to Save Energy During the Holidays | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy Usage »of EnergyThe EnergyDepartment7 th , 2007Timothy Runyon About UsGreen

98

Workers Across the Nuclear Security Enterprise Give Back This Holiday  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLasDelivered energy consumption byAbout PrintableBlenderWhatFellowsWood and4213WorkWork

99

How Do Holiday Lights Work? | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in3.pdfEnergy Health and ProductivityEnergyEnergy Fulfill Its Mission |Energy

100

Energy-Efficient Holiday Decorating Tips | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeat PumpRecord ofESPC ENABLE:2009Applications -Sessionfor Reviewin

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
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101

Solar Field Powers Historic Garden Holiday Display | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment of Energy U.S. DepartmentCommitmentGovernmentSmartDay 7 President'sThis is part

102

Leveraging Holidays and Other Events | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |EnergyonSupport0.pdf5 OPAM SEMIANNUAL REPORT TOJaredKansas1 - Energy Basics7-03ofLeveraging

103

Tips to Save Energy During the Holidays | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartment of Energyof theRestorationAdvisoryManagement and on

104

Buying an Appliance this Holiday Season? ENERGY STAR Products...  

Office of Environmental Management (EM)

Freezers Room air conditioners Televisions Clothes washers Dishwashers Battery chargers Water heaters Fluorescent lamp ballasts Incandescent reflector lamps If your appliance has...

105

Holiday Meal Packages Enjoy the holidays with pre-made hearty and delicious meals prepared by our Food Services staff.  

E-Print Network [OSTI]

: · Mashed Potatoes: 5 lb. pan. Serves 12-15. · Dressing: 5 lb. pan. Cook and serve, serves 12-15 · Cranberry.00 Cornbread Dressing $8.25 Mashed Potatoes $9.00 Cranberry Relish $5.00 Pumpkin Pie $8.00 Pecan Pie $8.00 Cornbread Dressing $8.25 Mashed Potatoes $9.00 Cranberry Relish $5.00 Pumpkin Pie $8.00 Pecan Pie $8

Oklahoma, University of

106

Regular-expression derivatives reexamined SCOTT OWENS  

E-Print Network [OSTI]

. For regular sets of strings, i.e., sets defined by regular expressions (REs), the derivative is also a regular is elegant and easily supports extended regular expressions; i.e., REs extended with Boolean operations expressions, but since the extensions are conservative (i.e., regular languages are closed under Boolean

Strickland, Stevie

107

Federal Express | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revision has beenFfe2fb55-352f-473b-a2dd-50ae8b27f0a6 NoSan Leandro,LawFEMAProjectExpress Jump to: navigation,

108

The Use of EST Expression Matrixes for the Quality Control of Gene Expression Data  

E-Print Network [OSTI]

for tissue typing and quality control of libraries as small as just a few hundred total ESTs. Furthermore, weThe Use of EST Expression Matrixes for the Quality Control of Gene Expression Data Andrew T Expression Matrixes for the Quality Control of Gene Expression Data. PLoS ONE 7(3): e32966. doi:10

Sheldon, Nathan D.

109

Methods for monitoring multiple gene expression  

DOE Patents [OSTI]

The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing Trichoderma reesei ESTs or SSH clones, or a combination thereof. The present invention also relates to computer readable media and substrates containing such array features for monitoring expression of a plurality of genes in filamentous fungal cells.

Berka, Randy; Bachkirova, Elena; Rey, Michael

2013-10-01T23:59:59.000Z

110

Methods for monitoring multiple gene expression  

SciTech Connect (OSTI)

The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing Trichoderma reesei ESTs or SSH clones, or a combination thereof. The present invention also relates to computer readable media and substrates containing such array features for monitoring expression of a plurality of genes in filamentous fungal cells.

Berka, Randy (Davis, CA); Bachkirova, Elena (Davis, CA); Rey, Michael (Davis, CA)

2012-05-01T23:59:59.000Z

111

Rocky Mountain Power- FinAnswer Express  

Broader source: Energy.gov [DOE]

Rocky Mountain Power's FinAnswer Express Program provides extensive incentives and for lighting, HVAC, food service, agricultural, and compressed air equipment. Retrofits of facilities and upgrades...

112

Pacific Power- FinAnswer Express  

Broader source: Energy.gov [DOE]

Pacific Power's FinAnswer Express Program includes incentives and technical assistance for lighting, HVAC and other equipment upgrades that increase energy efficiency and exceed code requirements...

113

Pooled ORF Expression Technology (POET) USING PROTEOMICS TO SCREEN POOLS OF OPEN READING FRAMES FOR PROTEIN EXPRESSION*S  

E-Print Network [OSTI]

are greatly simplified. Small scale expression and purification of 12 positive clones identified by POET from as much protein as 12 negative clones. Larger scale expression and purification of six of the positive attempted (4). In the standard approach to high throughput protein ex- pression and purification used

114

EXPRESSIVE ROBOTICS SCHOLARSHIPS SUMMER 2014 Scholarship Guidelines  

E-Print Network [OSTI]

EXPRESSIVE ROBOTICS SCHOLARSHIPS SUMMER 2014 Scholarship Guidelines PURPOSE To provide access to the Beall Center's Expressive Robotics summer intensive offered at the UC Irvine Claire Robotics is a twoweek middle/high school aged summer program focused on the development of robotic

Loudon, Catherine

115

Supervised Harvesting of Expression Trees Trevor Hastie  

E-Print Network [OSTI]

Supervised Harvesting of Expression Trees Trevor Hastie #3; , Robert Tibshirani y , David Botstein learning from gene ex- pression data. We call it \\Tree Harvesting". This technique starts between genes. Conclusions Tree Harvesting is a potentially useful tool for exploration of gene expression

Hastie, Trevor

116

Oct-4 expression in equine embryonic cells  

E-Print Network [OSTI]

(ES) cells for this reason. Until 1999, Oct-4 studies were limited to in vivo-produced embryos; equine embryos have not been studied for their Oct-4 expression patterns. In addition, equine stem-like cells (defined by marker expression, induced...

Harding, Heather Darby

2007-04-25T23:59:59.000Z

117

TroubleshootingGuide A. Protein Expression  

E-Print Network [OSTI]

binding b) Dilute an aliquot of lysate (1:10), or sonicate, and check binding on a small scale. c) Try. Apparent low · Insoluble Use denaturing extraction expression over-expressed and purification conditions sample for purification after proper buffering B. Loading/Washing Problem Possible Cause Solution 1

Lebendiker, Mario

118

Expression of eukaryotic polypeptides in chloroplasts  

DOE Patents [OSTI]

The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.

Mayfield, Stephen P

2013-06-04T23:59:59.000Z

119

Small Business Express Program (EXP) (Connecticut)  

Broader source: Energy.gov [DOE]

The Small Business Express Program (EXP) provides loans and grants to small businesses (not more than 100 employees) to spur job creation and growth. The Program provides access to capital through...

120

An expectation model of referring expressions  

E-Print Network [OSTI]

This thesis introduces EMRE, an expectation-based model of referring expressions. EMRE is proposed as a model of non-syntactic dependencies - in particular, discourse-level semantic dependencies that bridge sentence gaps. ...

Kræmer, John, Ph. D. Massachusetts Institute of Technology

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

On expressive punishment and holisitic desert  

E-Print Network [OSTI]

are cleared up and made consistent through employing a holistic notion of punitive desert. Holism is the view that accurate desert judgments must reference an actually obtaining just distribution of punishment. In my view, the expressive function is feasible...

Greenblum, Jake

2009-05-15T23:59:59.000Z

122

Generating and interpreting referring expressions in context  

E-Print Network [OSTI]

Referring expressions with vague and ambiguous modifiers, such as "a quick visit" and "the big meeting," are difficult for computers to interpret because their meanings are defined in part by context. For the hearer to ...

Smith, Dustin Arthur

2013-01-01T23:59:59.000Z

123

TrekISM Issue 67  

E-Print Network [OSTI]

. Write to Vulkon, PO Box 786, Hollywood FL 33022-0786. STAR-FEST - March 22-24, Holiday Inn, Denver CO. Guests: Leonard Nimoy, Colm Meany. Write to: Starland, 8200 East Pacific Place, #307, Denver CO 80231 DREAMWERKS - April 6-7, Cleveland Guest....00 or send a SASE with two stams for an updated flyer and sample issue. Regina Moore, 7755 E. Quincy Ave #D3-302, Denver, CO 80237 [Ed note: Though Regina didnlt mention an age statement for her publi- cation, by its very nature K/S is a genre usually...

1990-01-01T23:59:59.000Z

124

Report on the technical workshop on WTI incinerator risk issues. Held in Washington, DC on December 8-9, 1993  

SciTech Connect (OSTI)

The report includes information and materials from a peer review workshop organized by EPA's Risk Assessment Forum (RAF) for the Office of Solid Waste and Emergency Response and Region 5. The meeting was held in Washington, DC, at the Holiday Inn Capitol on December 8-9, 1993. The subject of the peer review was a draft project plan prepared by EPA Region 5 for assessing risk at an incinerator operated by Waste Technologies Industries (WTI) in East Liverpool, Ohio. The peer review panel was convened to evaluate the project plan as the scientific foundation for a risk assessment, which will be used in setting final permit conditions for the WTI facility.

Not Available

1993-12-01T23:59:59.000Z

125

The developmental expression dynamics of Drosophila melanogaster transcription factors  

E-Print Network [OSTI]

-specific activation and repression of genes. The expression of TFs should therefore reflect the core expression program of each cell. Results We studied the expression dynamics of about 750 TFs using the available genomics resources in Drosophila melanogaster. We find...

Adryan, Boris; Teichmann, Sarah A

2010-04-12T23:59:59.000Z

126

DOMESTIC SERVICES FEDERAL EXPRESS UPS US POSTAL SERVICE OTHER  

E-Print Network [OSTI]

SERVICES FEDERAL EXPRESS UPS US POSTAL SERVICE OTHER ___ First Overnight ___ Air ___ Regular Post _____________________________________ ___ Express Saver ___ Ground FEDERAL EXPRESS UPS US POSTAL SERVICE OTHER ___ Int. First ___ Air ___ Air Mail. Economy _____________________________________ Fill in complete mailing address. FedEx and UPS

Holliday, Vance T.

127

EIS-0447: Champlain Hudson Power Express Transmission Line Project...  

Broader source: Energy.gov (indexed) [DOE]

7: Champlain Hudson Power Express Transmission Line Project, New York EIS-0447: Champlain Hudson Power Express Transmission Line Project, New York Summary This EIS evaluates the...

128

albumin gene expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

biology, and multiple orthogonal gene switches are needed Zhao, Huimin 223 Metabolic load and heterologous gene expression CiteSeer Summary: The expression of a foreign...

129

abnormal phenotypic expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

D.R. and Linkenauger, S.A. (in press). Perception viewed as a phenotypic expression: Perception Viewed as a Phenotypic Expression Correspondence: Dennis Proffitt Department of...

130

A Hybrid Approach to Protein Differential Expression in Mass...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Hybrid Approach to Protein Differential Expression in Mass Spectrometry-Based Proteomics. A Hybrid Approach to Protein Differential Expression in Mass Spectrometry-Based...

131

Expressive Re-Performance Laurel S. Pardue  

E-Print Network [OSTI]

. There are two major components to perfor- mance: the technical requirement of correctly playing the notes, and the emotional content conveyed through expressivity. While technical details like pitch and note order instrument with which the user steps-through a recording. Data generated from the users actions is parsed

132

Ace Cash Express Advantage Sales and Marketing  

E-Print Network [OSTI]

Ace Cash Express Advantage Sales and Marketing AppFolio AT&T Atmos Energy, MDTX Div Automatic Data Processing AXA Advisors BDO USA Blue Cross & Blue Shield of Texas Care Providers Insurance Services CDW Corp State Farm Insurance Companies Tekzenit Texas Comptroller of Public Accounts Texas Department of Family

O'Toole, Alice J.

133

Materials and Methods Protein expression and purification  

E-Print Network [OSTI]

Materials and Methods Protein expression and purification The Full length Argonaute gene from protease system was a generous gift from Dr. Chris Lima. PfAgo was further purified with a heating step with #12;the program CNS (S7) against the SHARP amplitudes. Water molecules were added conservatively (for

Joshua-Tor, Leemor

134

The Research Express Volume 2, Issue 6  

E-Print Network [OSTI]

The Research Express Volume 2, Issue 6 TOP September 2 0 1 3 Image + NIH Requiring Tracking + Helpful Hints for Submitting a Successful NIH Proposal In the News... NIH to Require Tracking of Graduate and Undergraduate Students The National Institute of Health (NIH), in a move to improve data on NIH

Hutcheon, James M.

135

December 2010: Happy Holidays! We, in the School of Engineering, wish you all the best the season has to offer. Click here for our holiday greeting.  

E-Print Network [OSTI]

Meyyappan. More information. James Foley '68 honored by NCEES: Congratulations to civil engineering alumnus James Foley of Saratoga, CA, who was awarded the NCEES Distinguished Service Award for his dedicated service to the engineering and surveying professions. Foley has held numerous leadership positions

Holliday, JoAnne

136

Neurokinin Receptor Expression in the Lymphatic System  

E-Print Network [OSTI]

for the designation as UNDERGRADUATE RESEARCH SCHOLAR A Senior Scholars Thesis by PARTH VIJAY KHADE A Senior Scholars Thesis by Parth Vijay Khade Approved by: Research Advisor: Dave C. Zawieja Associate Dean for Undergraduate... for the designation as UNDERGRADUATE RESEARCH SCHOLAR iii ABSTRACT Neurokinin Receptor Expression in the Lymphatic System. (April 2009) Parth Vijay Khade Department of Biomedical Engineering Texas A&M University Research Advisor: Dr. Dave C...

Khade, Parth

2011-01-11T23:59:59.000Z

137

Kinetic decoupling of WIMPs: analytic expressions  

E-Print Network [OSTI]

We present a general expression for the values of the average kinetic energy and of the temperature of kinetic decoupling of a WIMP, valid for any cosmological model. We show an example of the usage of our solution when the Hubble rate has a power-law dependence on temperature, and we show results for the specific cases of kination cosmology and low- temperature reheating cosmology.

Visinelli, Luca

2015-01-01T23:59:59.000Z

138

Please fill in: Name/UM Registration # C380 Med Inn, SPC 5838  

E-Print Network [OSTI]

of the following cardiovascular or heart problems? a) Heart attack Yes No b) Stroke Yes No c) Angina Yes No d) Heart failure Yes No e) Swelling in your legs or feet (not caused by walking) Yes No f) Heart arrhythmia (heart beating irregularly) Yes No g) High blood pressure Yes No h) Any other heart problem that you

Shyy, Wei

139

Molecular beam epitaxy of InN dots on nitrided sapphire  

E-Print Network [OSTI]

potential in the optoelectronics industry. A well-knownsubstrate material in optoelectronics. In this work, we test

Romanyuk, Yaroslav E.; Dengel, Radu-Gabriel; Stebounova, Larissa V.; Leone, Stephen R.

2007-01-01T23:59:59.000Z

140

Electrical and Electrothermal Transport Properties of n- and p-type InN  

E-Print Network [OSTI]

?2 ) µ (cm 2 /Vs) Summary of electrical and thermoelectricVs) GS1548 GS1547 GS1810 GS1650 101107A 101107B 101107C Table 2.1 Summary of electricalVs) S665 S696 S601 S697 S625 S629 S599 Sample Table 3.2 Summary of electrical

Miller, Nathaniel Reed

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Electrical and Electrothermal Transport Properties of n- and p-type InN  

E-Print Network [OSTI]

methods . . . . . . . . . . . . 2.3 Electrical and1997). [132] Look, D. Electrical characterization of GaAsElectrical and Electrothermal Transport Properties of n- and

Miller, Nathaniel Reed

2010-01-01T23:59:59.000Z

142

Inn vati ns at EECS: Techn l gy f r a gl bal future  

E-Print Network [OSTI]

of Society Invention Lab 141/143 Sutardja Dai Hall Center for Research in Energy Systems Transformation 406 - Peter Bailis, AMPLab (Algorithms, Machines, and People Laboratory) · Raven: An Energy Wireless Research Center) & E3S (Center for Energy Efficient Electronics Science) · Occupant Detection

California at Irvine, University of

143

Electrical and Electrothermal Transport Properties of n- and p-type InN  

E-Print Network [OSTI]

Berlin , 265 (1823). [166] Peltier, J. Ann. Chim. Phys 56,which is also known as the Peltier coefficient. Note that p-en.wikipedia.org/wiki/Peltier Open source images under

Miller, Nathaniel Reed

2010-01-01T23:59:59.000Z

144

Konocti Harbor Inn Pool & Spa Low Temperature Geothermal Facility | Open  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to:46 - 429 Throttled (botOpen6Kentwood,GeorgeKlimaschutz eKodiak, Alaska:KonarkaEnergy

145

Lois Curfman McInnes, 2011 | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 IndustrialIsadore Perlman, 1960 The Ernest

146

Furnace Creek Inn Pool & Spa Low Temperature Geothermal Facility | Open  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation, search Equivalent URIFrontier,Jump to: navigation,Fuquay-Varina,

147

River Inn Natural Hot Spring Pool & Spa Low Temperature Geothermal Facility  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ < RAPID Jump to: navigation, searchVirginia Blue RidgeUniversityMedio, New Mexico:LimitedEdge, NewGrove

148

Riverside Inn Pool & Spa Low Temperature Geothermal Facility | Open Energy  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ < RAPID Jump to: navigation, searchVirginia Blue RidgeUniversityMedio,Riverhead, NewRiverside

149

The Saratoga Inn Pool & Spa Low Temperature Geothermal Facility | Open  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia:FAQ < RAPID Jump to:Seadov Pty LtdSteen,Ltd Jump Jump to:InformationThe Potomac Edison

150

8/20/2010 1 C380 Med Inn, SPC 5838  

E-Print Network [OSTI]

be noted that medical qualification for respirator use is dependent upon proper fit testing and instruction regarding use and maintenance of respiratory equipment. Clinician signature Date Name/UM Registration # #12;

Shyy, Wei

151

Ectopic ERK Expression Induces Phenotypic Conversion of C10 Cells and Alters DNA Methyltransferase Expression  

SciTech Connect (OSTI)

In some model systems constitutive extracellular signal regulated kinase (ERK) activation is sufficient to promote an oncogenic phenotype. Here we investigate whether constitutive ERK expression influences phenotypic conversion in murine C10 type II alveolar epithelial cells. C10 cells were stably transduced with an ERK1-green fluorescent protein (ERK1-GFP) chimera or empty vector and ectopic ERK expression was associated with the acquisition of soft agar focus-forming potential in late passage, but not early passage cells. Late passage ERK1-GFP cells exhibited a significant increase in the expression of DNA methyl transferases (DNMT1 and 3b) and a marked increase in sensitivity to 5-azacytidine (5-azaC)-mediated toxicity, relative to early passage ERK1-GFP cells and vector controls. The expression of xeroderma pigmentosum complementation group A (XPA) and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) were significantly increased in late passage cells, suggesting enhanced DNA damage recognition and repair activity which we interpret as a reflection of genomic instability. Phospho-ERK levels were dramatically decreased in late passage ERK1-GFP cells, relative to early passage and vector controls, and phospho-ERK levels were restored by treatment with sodium orthovanadate, indicating a role for phosphatase activity in this response. Collectively these observations suggest that ectopic ERK expression promotes phenotypic conversion of C10 cells that is associated with latent effects on epigenetic programming and phosphatase activities.

Sontag, Ryan L.; Weber, Thomas J.

2012-05-04T23:59:59.000Z

152

Generating and Interpreting Referring Expressions in Dustin Arthur Smith  

E-Print Network [OSTI]

Generating and Interpreting Referring Expressions in Context by Dustin Arthur Smith B.S., Wake Referring Expressions in Context by Dustin Arthur Smith Submitted to the Program of Media Arts and Sciences, MIT Media Lab #12;Generating and Interpreting Referring Expressions in Context by Dustin Arthur Smith

153

CSP is expressive enough for A.W. Roscoe  

E-Print Network [OSTI]

CSP is expressive enough for A.W. Roscoe Oxford University Computing Laboratory {Bill.Roscoe@comlab.ox.ac.uk} Abstract. Recent results show that Hoare's CSP, augmented by one additional operator, can express every operator whose operational semantics are expressible in a new notation and are therefore "CSP

Oxford, University of

154

Reduced expression of Autographa californica nucleopolyhedrovirus ORF34, an essential gene, enhances heterologous gene expression  

SciTech Connect (OSTI)

Autographa californica multiple nucleopolyhedrovirus ORF34 is part of a transcriptional unit that includes ORF32, encoding a viral fibroblast growth factor (FGF) and ORF33. We identified ORF34 as a candidate for deletion to improve protein expression in the baculovirus expression system based on enhanced reporter gene expression in an RNAi screen of virus genes. However, ORF34 was shown to be an essential gene. To explore ORF34 function, deletion (KO34) and rescue bacmids were constructed and characterized. Infection did not spread from primary KO34 transfected cells and supernatants from KO34 transfected cells could not infect fresh Sf21 cells whereas the supernatant from the rescue bacmids transfection could recover the infection. In addition, budded viruses were not observed in KO34 transfected cells by electron microscopy, nor were viral proteins detected from the transfection supernatants by western blots. These demonstrate that ORF34 is an essential gene with a possible role in infectious virus production.

Salem, Tamer Z. [Department of Entomology, Michigan State University, East Lansing, MI 48824 (United States) [Department of Entomology, Michigan State University, East Lansing, MI 48824 (United States); Department of Microbial Molecular Biology, AGERI, Agricultural Research Center, Giza 12619 (Egypt); Division of Biomedical Sciences, Zewail University, Zewail City of Science and Technology, Giza 12588 (Egypt); Zhang, Fengrui [Department of Entomology, Michigan State University, East Lansing, MI 48824 (United States)] [Department of Entomology, Michigan State University, East Lansing, MI 48824 (United States); Thiem, Suzanne M., E-mail: smthiem@msu.edu [Department of Entomology, Michigan State University, East Lansing, MI 48824 (United States); Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824 (United States)

2013-01-20T23:59:59.000Z

155

MICRORNA EXPRESSION WITHIN PERIOVULATORY MURAL GRANULOSA CELLS  

E-Print Network [OSTI]

gene ................................................................ 89 Figure 4-2 Pri-miR 132/212 primer design ......................................... 91 Figure 4-3 qRT-PCR analysis of pri-miR-132/212 expression ........... 94 Figure 4-4 q...]. For example, the protein AUF1 mediates mRNA destabilization when bound to the ARE. In contrast, ARE-binding of He1-N1, HuC, HuD and HuR proteins has been associated with mRNA 5 stabilization [26] indicating a complex regulatory network for ARE containing...

Fiedler, Stephanie Deanne

2008-01-01T23:59:59.000Z

156

Expression of multiple proteins in transgenic plants  

DOE Patents [OSTI]

A method is disclosed for the production of multiple proteins in transgenic plants. A DNA construct for introduction into plants includes a provision to express a fusion protein of two proteins of interest joined by a linking domain including plant ubiquitin. When the fusion protein is produced in the cells of a transgenic plant transformed with the DNA construction, native enzymes present in plant cells cleave the fusion protein to release both proteins of interest into the cells of the transgenic plant. Since the proteins are produced from the same fusion protein, the initial quantities of the proteins in the cells of the plant are approximately equal.

Vierstra, Richard D. (Madison, WI); Walker, Joseph M. (Madison, WI)

2002-01-01T23:59:59.000Z

157

Express Package Shipping Services | The Ames Laboratory  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsing ZirconiaPolicy and Assistance100JeffersonMarkExploratorysurfaceExposureExpress

158

Peroxidase gene expression during tomato fruit ripening  

SciTech Connect (OSTI)

Auxin oxidation has been reported to play a critical role in the initiation of pear fruit ripening and a tomato fruit peroxidase (POD) has been shown to have IAA-oxidase activity. However, little is known about changes in the expression of POD mRNA in tomato fruit development. They are investigating the expression of POD mRNA during tomato fruit maturation. Fruit pericarp tissues from six stages of fruit development and ripening (immature green, mature green, breaker, turning, ripe, and red ripe fruits) were used to extract poly (A)/sup +/ RNAs. These RNAs were translated in vitro in a rabbit reticulocyte lysate system using L-/sup 35/S-methionine. The /sup 35/S-labeled products were immunoprecipitated with POD antibodies to determine the relative proportions of POD mRNA. High levels of POD mRNA were present in immature green and mature green pericarp, but declined greatly by the turning stage of fruit ripening. In addition, the distribution of POD mRNA on free vs bound polyribosomes will be presented, as well as the presence or absence of POD mRNA in other tomato tissues.

Biggs, M.S.; Flurkey, W.H.; Handa, A.K.

1987-04-01T23:59:59.000Z

159

Bismuth Dimercaptopropanol (BisBAL) Inhibits the Expression of...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

(3-dimercapto-1-propanol, BAL)significantly reduced extracellular polymeric substances (EPS) expression by Brevundimonas diminuta in suspended cultures at levels just below the...

160

assess expression profiles: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the application of a novel clustering algorithm, Super-Paramagnetic Clustering (SPC) to analysis of gene expression profiles that were generated recently during a study of...

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

acc synthase expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

corroborate asymmetry of catalysis in F0F1-ATP synthase. Zarrabi, Nawid; Diez, Manuel; Graeber, Peter; Wrachtrup, Joerg; Boersch, Michael 2007-01-01 202 expression? Environments...

162

Final EIS for Champlain Hudson Power Express Transmission Project...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

1021). The proposed DOE action addressed in the Final EIS is to issue a Presidential permit to the Applicant, Champlain Hudson Power Express, Inc. (CHPEI), that would allow...

163

Genomics, Gene Expression and Other Studies in Soybean Rust  

E-Print Network [OSTI]

Joint Genome Institute Genomics, Gene Expression and otherRust Martha Lucía Posada-Buitrago Ph.D Genomics DivisionEvolutionary Genomics DOE- Joint Genome Institute Lawrence

Posada-Buitrago, Martha Lucia

2005-01-01T23:59:59.000Z

164

Single cell growth and gene expression dynamics in model organisms  

E-Print Network [OSTI]

Quake, S. R. , 2003: Microfluidics in structural biology:Lee Pang, for his microfluidics expertise, Scott Cookson,and Expression Assays Microfluidics-assisted Microscopy

Cookson, Natalie Anne

2009-01-01T23:59:59.000Z

165

Snohomish County PUD No 1- Solar Express Rebate Program  

Broader source: Energy.gov [DOE]

In March 2009, Snohomish County PUD introduced the Solar Express Program. This program provides rebates to support residential and commercial installations of solar photovoltaics (PV) and solar...

166

acid decarboxylase expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the expressions. Anna Sthl; Petra Sundstrm; Kristina Hk 2005-01-01 180 ANTIBODY PURIFICATION USING CAPRYLIC ACID In mildly acidic conditions, the addition of short-chain...

167

Add to your Holiday menu: "Canap ", a glass of punch during cocktail hour  

E-Print Network [OSTI]

Spinach and cranberry salad with goat cheese Salmon tartar and crispy ginger.00 Caesar salad Choose one of the following : Turkey roast with cranberry

168

Effect of iron concentration on growth and phylloclade edge yellowing of holiday cactus  

E-Print Network [OSTI]

with applied Fe concentration, and if temperature and pH of the growing media affected Fe uptake. In two separate studies, rooted cuttings of Schlumbergera 'White Christmas,"Twilight Tangerine,"Christmas Charm,'and 'Lavender Doll'were placed in either a peat...

Ramirez, Dario

1996-01-01T23:59:59.000Z

169

Sales Tax Exemption for Energy-Efficient Products (Sales Tax Holiday) (Georgia))  

Broader source: Energy.gov [DOE]

Georgia allows an annual state and local sales tax exemption on Energy Star products of $1,500 or less per product, purchased for non-commercial home or personal use.The 100% exemption from the...

170

Sales Tax Exemption for Energy-Efficient Products (Sales Tax Holiday)  

Broader source: Energy.gov [DOE]

Virginia allows a four-day sales tax exemption on Energy Star products of $2,500 or less per product, purchased for non-commercial home or personal use. Beginning in 2007, the 100% exemption from...

171

EECBG Success Story: North Pole's Holiday Wish for an Energy Efficient 2012  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in Review: TopEnergy DOEDealingVehicle1 ClosingA Tradition ofOregonPower | Department|

172

Buying an Appliance this Holiday Season? ENERGY STAR Products will Save You  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehicles » AlternativeUp Home Energy-Efficiency Building UpMoney and Energy

173

Cut Gas Costs This Holiday Traveling Season with Three Easy Tips |  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehicles » AlternativeUp HomeHorse BackwardsProjectCriminalDepartment of

174

How do You Save Energy During the Holidays? | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists'Montana.ProgramJulietip sheetK-4In 2013Department of EnergyFuelEnergy

175

Video e-card offers holiday greetings from everyone at PPPL | Princeton  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism inS-4500IIVasudha PatriPhotoelectron Spectroscopy ofVictorLibrary

176

What Do You Think of Your LED Holiday Lights? | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment of Energy WhileTanklessLES' URENCO-USAWesternDepartment ofThis

177

They're Here! Winter, Holidays, and the New Year. How Will You Save Energy?  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy Usage »of EnergyThe EnergyDepartment ofPoweredEngine-Powered2 DOE Hydrogen|

178

North Pole's Holiday Wish for An Energy Efficient 2012 | Department of  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in3.pdfEnergyDepartment of Energy Advanced Framing -Nissan:DepartmentDakota

179

Reduce Waste and Save Energy this Holiday Season | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: AlternativeEnvironment,Institutes and Launches theResidentialRecoveryWaste and Save Energy this

180

Y-12 employees help make holiday merrier for many | Y-12 National Security  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLasDelivered energy consumption byAbout SRNL Home SRNL mainEmployees &andComplex help

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Y-12 helps more than 600 kids for the holidays | National Nuclear Security  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLasDelivered energy consumption byAbout SRNL Home SRNL mainEmployeesresearch reactor

182

Top 5 Things You Didn't Know About Holiday Lights | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of EnergyEnergyENERGYWomenthe House Committee on EnergyEnergyThe sun rises on| DepartmentDepartmentWith

183

Y-12 employees make holiday merry for local families | National Nuclear  

National Nuclear Security Administration (NNSA)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartmentNational NuclearhasAdministration go on moonAdministration

184

South Carolina Community Lights Up the Season with Energy-Efficient Holiday  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartment of Energyof the Americas |DOEEnergy32.1 (October 2011) 1Lights | Department

185

Question of the Week: What Are You Doing to Save Energy this Holiday  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists' Research | DepartmentDepartmentHatch, Maryanne5 UpdatescommentsQueryl

186

How Do You Save Money on Summer Holidays? | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeatMulti-Dimensional Subject:Ground HawaiiWasteDepartmentHoney,in the Kitchen? How

187

Analysis of SNP-Expression Association Matrices Anya Tsalenko1  

E-Print Network [OSTI]

, 3500 Deer Creek Road, Palo Alto CA 94304, USA 2 School of Computer Science, Tel-Aviv University, Tel provide the means to study the genetic determinants of population variation in gene expression variation expression in three species, with an emphasis on mice. They produced a genetically diverse population of 111

Shamir, Ron

188

Characterization of a Gene Abundantly Expressed in Stallion Testis  

E-Print Network [OSTI]

a miRNA qRT-PCR assay to determine the expression levels in stallion testis samples from fertile and sub-fertile stallions. We observed similar expression among both groups and the ratio of mRNA to miRNA did not appear constant. We also investigated...

Shields, Jordan Elizabeth

2012-02-14T23:59:59.000Z

189

Expressing Help at Appropriate Levels Oscar D. Andrade  

E-Print Network [OSTI]

Expressing Help at Appropriate Levels Oscar D. Andrade Department of Computer Science@utep.edu ABSTRACT Users of help systems often complain that the documentation is pitched at the wrong level of documentation in terms of task, application, and user experience, we explore what it means to express help

Novick, David G.

190

Systematic Dissection of the Determinants of HIV Expression Noise  

E-Print Network [OSTI]

six days post infection, gene expression was stimulated with 20 ng/ ml tumor necrosis factor-oc (TNF-oc, Sigma-six days post infection, gene expression was stimulated with 20 ng/ml tumor necrosis factor-on (TNF-(1, 29 Sigma-

Foley, Jonathan Emmett

2013-01-01T23:59:59.000Z

191

On the expressiveness of CSP A.W. Roscoe  

E-Print Network [OSTI]

On the expressiveness of CSP A.W. Roscoe February 16, 2011 Abstract We define "CSP express every operator of Hoare's CSP. Furthermore we show that every op- erator with CSP-like operational semantics can be simulated in CSP with the addition of an exception-throwing operator P A Q in which any

Oxford, University of

192

Massively parallel processor networks with optical express channels  

DOE Patents [OSTI]

An optical method for separating and routing local and express channel data comprises interconnecting the nodes in a network with fiber optic cables. A single fiber optic cable carries both express channel traffic and local channel traffic, e.g., in a massively parallel processor (MPP) network. Express channel traffic is placed on, or filtered from, the fiber optic cable at a light frequency or a color different from that of the local channel traffic. The express channel traffic is thus placed on a light carrier that skips over the local intermediate nodes one-by-one by reflecting off of selective mirrors placed at each local node. The local-channel-traffic light carriers pass through the selective mirrors and are not reflected. A single fiber optic cable can thus be threaded throughout a three-dimensional matrix of nodes with the x,y,z directions of propagation encoded by the color of the respective light carriers for both local and express channel traffic. Thus frequency division multiple access is used to hierarchically separate the local and express channels to eliminate the bucket brigade latencies that would otherwise result if the express traffic had to hop between every local node to reach its ultimate destination.

Deri, Robert J. (Pleasanton, CA); Brooks, III, Eugene D. (Livermore, CA); Haigh, Ronald E. (Tracy, CA); DeGroot, Anthony J. (Castro Valley, CA)

1999-01-01T23:59:59.000Z

193

Massively parallel processor networks with optical express channels  

DOE Patents [OSTI]

An optical method for separating and routing local and express channel data comprises interconnecting the nodes in a network with fiber optic cables. A single fiber optic cable carries both express channel traffic and local channel traffic, e.g., in a massively parallel processor (MPP) network. Express channel traffic is placed on, or filtered from, the fiber optic cable at a light frequency or a color different from that of the local channel traffic. The express channel traffic is thus placed on a light carrier that skips over the local intermediate nodes one-by-one by reflecting off of selective mirrors placed at each local node. The local-channel-traffic light carriers pass through the selective mirrors and are not reflected. A single fiber optic cable can thus be threaded throughout a three-dimensional matrix of nodes with the x,y,z directions of propagation encoded by the color of the respective light carriers for both local and express channel traffic. Thus frequency division multiple access is used to hierarchically separate the local and express channels to eliminate the bucket brigade latencies that would otherwise result if the express traffic had to hop between every local node to reach its ultimate destination. 3 figs.

Deri, R.J.; Brooks, E.D. III; Haigh, R.E.; DeGroot, A.J.

1999-08-24T23:59:59.000Z

194

Probing cell-free gene expression noise in femtoliter volumes  

SciTech Connect (OSTI)

Cell-free systems offer a simplified and flexible context that enables important biological reactions while removing complicating factors such as fitness, division, and mutation that are associated with living cells. However, cell-free expression in unconfined spaces is missing important elements of expression in living cells. In particular, the small volume of living cells can give rise to significant stochastic effects, which are negligible in bulk cell-free reactions. Here, we confine cell-free gene expression reactions to cell relevant 20 fL volumes (between the volumes of E. coli and S. cerevisiae), in polydimethylsiloxane (PDMS) containers. We demonstrate that expression efficiency varies widely at this volume, and we analyze gene expression noise. Noise analysis reveals signatures of translational bursting while noise dynamics suggest that overall cell-free expression is limited by a diminishing translation rate. In addition to offering a unique approach to understanding noise in gene circuits, our work contributes to a deeper understanding of the biophysical properties of cell-free expression systems, thus aiding efforts to harness cell-free systems for synthetic biology applications.

Karig, David K [ORNL; Jung, Seung-Yong [ORNL; Srijanto, Bernadeta R [ORNL; Collier, Pat [ORNL; Simpson, Michael L [ORNL

2013-01-01T23:59:59.000Z

195

Combined hairpin-antisense compositions and methods for modulating expression  

DOE Patents [OSTI]

A nucleotide construct comprising a nucleotide sequence that forms a stem and a loop, wherein the loop comprises a nucleotide sequence that modulates expression of a target, wherein the stem comprises a nucleotide sequence that modulates expression of a target, and wherein the target modulated by the nucleotide sequence in the loop and the target modulated by the nucleotide sequence in the stem may be the same or different. Vectors, methods of regulating target expression, methods of providing a cell, and methods of treating conditions comprising the nucleotide sequence are also disclosed.

Shanklin, John; Nguyen, Tam

2014-08-05T23:59:59.000Z

196

Enhanced chloroplast transgene expression in a nuclear mutant of Chlamydomonas  

E-Print Network [OSTI]

, microalgae, Chlamydomonas rein- hardtii. Summary Chloroplast transformation in microalgae offers great promise for the production of proteins of pharmaceutical interest or for the development of novel biofuels in the chloroplast and improve transgene expression. Introduction Microalgae are attracting increasing interest

Halazonetis, Thanos

197

aging decreases expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

interacting sensory stimuli... Duncan, Nikki 2013-03-13 35 Analysis of Telomere Length in the Aged mdx Diaphragm with and without Transgenic IGF-I Expression CiteSeer...

198

Compiling Path Expressions into VLSI Circuits `I`. S. Annntharaman  

E-Print Network [OSTI]

-timed. Ncvcrthdcss. UK circuits produced by our construction have area propordonal to N slog(N) whcrc N is the total expression: path R, + Wend, path R, + Wend. `fhc first path cxprcssion prohibits a read operation

Clarke, Edmund M.

199

adaptor protein expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

cells before meiosis. After Smith, Steven E. 175 Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression CiteSeer Summary: Acrolein is a...

200

activation protein expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the relative rates of protein synthesis 98 Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression CiteSeer Summary: Acrolein is a...

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Propagation networks : a flexible and expressive substrate for computation  

E-Print Network [OSTI]

In this dissertation I propose a shift in the foundations of computation. Modem programming systems are not expressive enough. The traditional image of a single computer that has global effects on a large memory is too ...

Radul, Alexey

2009-01-01T23:59:59.000Z

202

adipose tissue expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the expression of the UCP1 gene 293 D. Norepinephrine is an apoptosis inhibitor in brown adipocytes 294 IV. How Significant Is Brown Adipose Tissue? 295 A. Parameters of...

203

ankara vaccine expressing: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

21 22 23 24 25 Next Page Last Page Topic Index 1 Role of Vaccination in the Control of Turkey Coccidiosis: Vaccine Associated Oocyst Shedding, Lesions, and Mucosal Gene Expression...

204

antigen expression varies: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Ikeda; Kazuo Katoh; Hiroyuki Koshimoto; Yoshihiro Yoshihara; Kensaku Mori 1993-01-01 10 NANO EXPRESS Open Access AuPd core-shell nanoparticles with varied hollow Energy Storage,...

205

Automatic 3D facial expression analysis in videos  

E-Print Network [OSTI]

with the background in videos [26] are important topics forSystem for Real-Time 3D Video. IEEE Int. Workshop onExpression Analysis in Videos Ya Chang 1 , Marcelo Vieira

Chang, Y; Vieira, M; Turk, M; Velho, L

2005-01-01T23:59:59.000Z

206

Data mining techniques for large-scale gene expression analysis  

E-Print Network [OSTI]

Modern computational biology is awash in large-scale data mining problems. Several high-throughput technologies have been developed that enable us, with relative ease and little expense, to evaluate the coordinated expression ...

Palmer, Nathan Patrick

2011-01-01T23:59:59.000Z

207

antibody expressing pea: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

can induce gene expression changes 10 Cooking and Using Dried Beans and Peas Renewable Energy Websites Summary: beans or peas with fresh water. Add 1 tablespoon of oil or other...

208

The Role of Multiple Transcription Factors In Archaeal Gene Expression  

SciTech Connect (OSTI)

Since the inception of this research program, the project has focused on two central questions: What is the relationship between the 'eukaryal-like' transcription machinery of archaeal cells and its counterparts in eukaryal cells? And, how does the archaeal cell control gene expression using its mosaic of eukaryal core transcription machinery and its bacterial-like transcription regulatory proteins? During the grant period we have addressed these questions using a variety of in vivo approaches and have sought to specifically define the roles of the multiple TATA binding protein (TBP) and TFIIB-like (TFB) proteins in controlling gene expression in Haloferax volcanii. H. volcanii was initially chosen as a model for the Archaea based on the availability of suitable genetic tools; however, later studies showed that all haloarchaea possessed multiple tbp and tfb genes, which led to the proposal that multiple TBP and TFB proteins may function in a manner similar to alternative sigma factors in bacterial cells. In vivo transcription and promoter analysis established a clear relationship between the promoter requirements of haloarchaeal genes and those of the eukaryal RNA polymerase II promoter. Studies on heat shock gene promoters, and the demonstration that specific tfb genes were induced by heat shock, provided the first indication that TFB proteins may direct expression of specific gene families. The construction of strains lacking tbp or tfb genes, coupled with the finding that many of these genes are differentially expressed under varying growth conditions, provided further support for this model. Genetic tools were also developed that led to the construction of insertion and deletion mutants, and a novel gene expression scheme was designed that allowed the controlled expression of these genes in vivo. More recent studies have used a whole genome array to examine the expression of these genes and we have established a linkage between the expression of specific tfb genes and the regulation of nitrogen metabolism and other global cellular responses.

Charles J. Daniels

2008-09-23T23:59:59.000Z

209

Affectiva-MIT Facial Expression Dataset (AM-FED): Naturalistic and Spontaneous Facial Expressions Collected In-the-Wild  

E-Print Network [OSTI]

Computer classification of facial expressions requires large amounts of data and this data needs to reflect the diversity of conditions seen in real applications. Public datasets help accelerate the progress of research ...

McDuff, Daniel Jonathan

210

Gene expression profiles of Nitrosomonas europaea, an obligate chemolitotroph  

SciTech Connect (OSTI)

Nitrosomonas europaea is an aerobic lithoautotrophic bacterium that uses ammonia (NH3) as its energy source. As a nitrifier, it is an important participant in the nitrogen cycle, which can also influence the carbon cycle. The focus of this work was to explore the genetic structure and mechanisms underlying the lithoautotrophic growth style of N. europaea. Whole genome gene expression. The gene expression profile of cells in exponential growth and during starvation was analyzed using microarrays. During growth, 98% of the genes increased in expression at least two fold compared to starvation conditions. In growing cells, approximately 30% of the genes were expressed eight fold higher, Approximately 10% were expressed more than 15 fold higher. Approximately 3% (91 genes) were expressed to more than 20 fold of their levels in starved cells. Carbon fixation gene expression. N. europaea fixes carbon via the Calvin-Benson-Bassham (CBB) cycle via a type I ribulose bisphosphate carboxylase/oxygenase (RubisCO). This study showed that transcription of cbb genes was up-regulated when the carbon source was limited, while amo, hao and other energy harvesting related genes were down-regulated. Iron related gene expression. Because N. europaea has a relatively high content of hemes, sufficient Fe must be available in the medium for it to grow. The genome revealed that approximately 5% of the coding genes in N. europaea are dedicated to Fe transport and assimilation. Nonetheless, with the exception of citrate biosynthesis genes, N. europaea lacks genes for siderophore production. The Fe requirements for growth and the expression of the putative membrane siderophore receptors were determined. The N. europaea genome has over 100 putative genes ({approx}5% of the coding genes) related to Fe uptake and its siderophore receptors could be grouped phylogenetically in four clusters. Fe related genes, such as a number of TonB-dependent Fe-siderophore receptors for ferrichrome and enterobactin, and diffusion protein OmpC were expressed to higher levels under Fe limitation. N. europaea has a high Fe requirement and under Fe limiting conditions (0.2 ?M), is capable to assimilate up to 70% of the available Fe without the ability to produce siderophores.

Daniel J Arp

2005-06-15T23:59:59.000Z

211

Gene expression profiles of Nitrosomonas europaea, an obligate chemolitotroph  

SciTech Connect (OSTI)

Nitrosomonas europaea is an aerobic lithoautotrophic bacterium that uses ammonia (NH3) as its energy source. As a nitrifier, it is an important participant in the nitrogen cycle, which can also influence the carbon cycle. The focus of this work was to explore the genetic structure and mechanisms underlying the lithoautotrophic growth style of N. europaea. Whole genome gene expression: The gene expression profile of cells in exponential growth and during starvation was analyzed using microarrays. During growth, 98% of the genes increased in expression at least two fold compared to starvation conditions. In growing cells, approximately 30% of the genes were expressed eight fold higher, Approximately 10% were expressed more than 15 fold higher. Approximately 3% (91 genes) were expressed to more than 20 fold of their levels in starved cells. Carbon fixation gene expression: N. europaea fixes carbon via the Calvin-Benson-Bassham (CBB) cycle via a type I ribulose bisphosphate carboxylase/oxygenase (RubisCO). This study showed that transcription of cbb genes was up-regulated when the carbon source was limited, while amo, hao and other energy harvesting related genes were down-regulated. Iron related gene expression: Because N. europaea has a relatively high content of hemes, sufficient Fe must be available in the medium for it to grow. The genome revealed that approximately 5% of the coding genes in N. europaea are dedicated to Fe transport and assimilation. Nonetheless, with the exception of citrate biosynthesis genes, N. europaea lacks genes for siderophore production. The Fe requirements for growth and the expression of the putative membrane siderophore receptors were determined. The N. europaea genome has over 100 putative genes ({approx}5% of the coding genes) related to Fe uptake and its siderophore receptors could be grouped phylogenetically in four clusters. Fe related genes, such as a number of TonB-dependent Fe-siderophore receptors for ferrichrome and enterobactin, and diffusion protein OmpC were expressed to higher levels under Fe limitation. N. europaea has a high Fe requirement and under Fe limiting conditions (0.2 {micro}M), is capable to assimilate up to 70% of the available Fe without the ability to produce siderophores.

Daniel J. Arp

2005-05-25T23:59:59.000Z

212

E-Print Network 3.0 - antisense rna expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

can affect gene expression via RNA editing or RNA interference mechanisms. microRNAs (mi... -deficient mice (mld) an abnormal antisense RNA drastically reduces expression of...

213

E-Print Network 3.0 - anoxia-responsive gene expression Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Abstract Motivation: A central step in the analysis of gene expression data is the identification of groups... of genes that exhibit similar expression patterns. ... Source:...

214

DOE Seeks Public-Private Sector Expressions of Interest for Global...  

Energy Savers [EERE]

Public-Private Sector Expressions of Interest for Global Nuclear Energy Partnership Initiative DOE Seeks Public-Private Sector Expressions of Interest for Global Nuclear Energy...

215

E-Print Network 3.0 - altered expression pattern Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Medicine 51 A Scalable Hybrid Regular Expression Pattern Matcher James Moscola, Young H. Cho, John W. Lockwood Summary: A Scalable Hybrid Regular Expression Pattern Matcher...

216

Gene co-expression network analysis in Rhodobacter capsulatus and application to comparative expression analysis of Rhodobacter sphaeroides  

SciTech Connect (OSTI)

The genus Rhodobacter contains purple nonsulfur bacteria found mostly in freshwater environments. Representative strains of two Rhodobacter species, R. capsulatus and R. sphaeroides, have had their genomes fully sequenced and both have been the subject of transcriptional profiling studies. Gene co-expression networks can be used to identify modules of genes with similar expression profiles. Functional analysis of gene modules can then associate co-expressed genes with biological pathways, and network statistics can determine the degree of module preservation in related networks. In this paper, we constructed an R. capsulatus gene co-expression network, performed functional analysis of identified gene modules, and investigated preservation of these modules in R. capsulatus proteomics data and in R. sphaeroides transcriptomics data. Results: The analysis identified 40 gene co-expression modules in R. capsulatus. Investigation of the module gene contents and expression profiles revealed patterns that were validated based on previous studies supporting the biological relevance of these modules. We identified two R. capsulatus gene modules preserved in the protein abundance data. We also identified several gene modules preserved between both Rhodobacter species, which indicate that these cellular processes are conserved between the species and are candidates for functional information transfer between species. Many gene modules were non-preserved, providing insight into processes that differentiate the two species. In addition, using Local Network Similarity (LNS), a recently proposed metric for expression divergence, we assessed the expression conservation of between-species pairs of orthologs, and within-species gene-protein expression profiles. Conclusions: Our analyses provide new sources of information for functional annotation in R. capsulatus because uncharacterized genes in modules are now connected with groups of genes that constitute a joint functional annotation. We identified R. capsulatus modules enriched with genes for ribosomal proteins, porphyrin and bacteriochlorophyll anabolism, and biosynthesis of secondary metabolites to be preserved in R. sphaeroides whereas modules related to RcGTA production and signalling showed lack of preservation in R. sphaeroides. In addition, we demonstrated that network statistics may also be applied within-species to identify congruence between mRNA expression and protein abundance data for which simple correlation measurements have previously had mixed results.

Pena-Castillo, Lourdes; Mercer, Ryan; Gurinovich, Anastasia; Callister, Stephen J.; Wright, Aaron T.; Westbye, Alexander; Beatty, J. T.; Lang, Andrew S.

2014-08-28T23:59:59.000Z

217

Recombinant cells that highly express chromosomally-integrated heterologous genes  

DOE Patents [OSTI]

Recombinant host cells are obtained that comprise (A) a heterologous, polypeptide-encoding polynucleotide segment, stably integrated into a chromosome, which is under transcriptional control of an endogenous promoter and (B) a mutation that effects increased expression of the heterologous segment, resulting in enhanced production by the host cells of each polypeptide encoded by that segment, relative to production of each polypeptide by the host cells in the absence of the mutation. The increased expression thus achieved is retained in the absence of conditions that select for cells displaying such increased expression. When the integrated segment comprises, for example, ethanol-production genes from an efficient ethanol producer like Zymomonas mobilis, recombinant Escherichia coli and other enteric bacterial cells within the present invention are capable of converting a wide range of biomass-derived sugars efficiently to ethanol.

Ingram, Lonnie O. (Gainesville, FL); Ohta, Kazuyoshi (Gainesville, FL); Wood, Brent E. (Gainesville, FL)

2000-08-22T23:59:59.000Z

218

Recombinant cells that highly express chromosomally-integrated heterologous genes  

DOE Patents [OSTI]

Recombinant host cells are obtained that comprise (A) a heterologous, polypeptide-encoding polynucleotide segment, stably integrated into a chromosome, which is under transcriptional control of an endogenous promoter and (B) a mutation that effects increased expression of the heterologous segment, resulting in enhanced production by the host cells of each polypeptide encoded by that segment, relative to production of each polypeptide by the host cells in the absence of the mutation. The increased expression thus achieved is retained in the absence of conditions that select for cells displaying such increased expression. When the integrated segment comprises, for example, ethanol-production genes from an efficient ethanol producer like Zymomonas mobilis, recombinant Escherichia coli and other enteric bacterial cells within the present invention are capable of converting a wide range of biomass-derived sugars efficiently to ethanol. 13 figs.

Ingram, L.O.; Ohta, Kazuyoshi; Wood, B.E.

1998-10-13T23:59:59.000Z

219

Recombinant cells that highly express chromosomally-integrated heterologous genes  

DOE Patents [OSTI]

Recombinant host cells are obtained that comprise (A) a heterologous, polypeptide-encoding polynucleotide segment, stably integrated into a chromosome, which is under transcriptional control of an endogenous promoter and (B) a mutation that effects increased expression of the heterologous segment, resulting in enhanced production by the host cells of each polypeptide encoded by that segment, relative to production of each polypeptide by the host cells in the absence of the mutation. The increased expression thus achieved is retained in the absence of conditions that select for cells displaying such increased expression. When the integrated segment comprises, for example, ethanol-production genes from an efficient ethanol producer like Zymomonas mobilis, recombinant Escherichia coli and other enteric bacterial cells within the present invention are capable of converting a wide range of biomass-derived sugars efficiently to ethanol.

Ingram, Lonnie O. (Gainesville, FL); Ohta, Kazuyoshi (Gainesville, FL); Wood, Brent E. (Gainesville, FL)

1998-01-01T23:59:59.000Z

220

p27{sup Kip1} inhibits tissue factor expression  

SciTech Connect (OSTI)

Highlights: •p27{sup Kip1}regulates the expression of tissue factor at the transcriptional level. •This inhibitory effect of p27{sup Kip1} is independently of its cell regulatory action. •The current study provides new insights into a pleiotrophic function of p27{sup Kip1}. -- Abstract: Background: The cyclin-dependent kinase inhibitor (CDKI) p27{sup Kip1} regulates cell proliferation and thus inhibits atherosclerosis and vascular remodeling. Expression of tissue factor (TF), the key initator of the coagulation cascade, is associated with atherosclerosis. Yet, it has not been studied whether p27{sup Kip1} influences the expression of TF. Methods and results: p27{sup Kip1} overexpression in human aortic endothelial cells was achieved by adenoviral transfection. Cells were rendered quiescent for 24 h in 0.5% fetal-calf serum. After stimulation with TNF-? (5 ng/ml), TF protein expression and activity was significantly reduced (n = 4; P < 0.001) in cells transfected with p27{sup Kip1}. In line with this, p27{sup Kip1} overexpression reduced cytokine-induced TF mRNA expression (n = 4; P < 0.01) and TF promotor activity (n = 4; P < 0.05). In contrast, activation of the MAP kinases p38, ERK and JNK was not affected by p27{sup Kip1} overexpression. Conclusion: This in vitro study suggests that p27{sup Kip1} inhibits TF expression at the transcriptional level. These data indicate an interaction between p27{sup Kip1} and TF in important pathological alterations such as atherosclerosis and vascular remodeling.

Breitenstein, Alexander, E-mail: alexander.breitenstein@usz.ch [Cardiology, University Heart Center, University Hospital Zurich (Switzerland) [Cardiology, University Heart Center, University Hospital Zurich (Switzerland); Cardiovascular Research, Physiology Institute, University of Zurich (Switzerland); Center for Integrative Human Physiology (ZHIP), University of Zurich (Switzerland); Akhmedov, Alexander; Camici, Giovanni G.; Lüscher, Thomas F.; Tanner, Felix C. [Cardiology, University Heart Center, University Hospital Zurich (Switzerland) [Cardiology, University Heart Center, University Hospital Zurich (Switzerland); Cardiovascular Research, Physiology Institute, University of Zurich (Switzerland); Center for Integrative Human Physiology (ZHIP), University of Zurich (Switzerland)

2013-10-04T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Robust expression of a bioactive mammalian protein in chlamydomonas chloroplast  

DOE Patents [OSTI]

Methods and compositions are disclosed to engineer chloroplast comprising heterologous mammalian genes via a direct replacement of chloroplast Photosystem II (PSII) reaction center protein coding regions to achieve expression of recombinant protein above 5% of total protein. When algae is used, algal expressed protein is produced predominantly as a soluble protein where the functional activity of the peptide is intact. As the host algae is edible, production of biologics in this organism for oral delivery or proteins/peptides, especially gut active proteins, without purification is disclosed.

Mayfield, Stephen P. (Cardiff, CA)

2010-03-16T23:59:59.000Z

222

Defining, expressing, and using context in a simulation environment  

SciTech Connect (OSTI)

Reuse and interoperability are two keywords in the mantra of the modeling and simulation community. In order to achieve these goals, one must be able to capture, express, and manage the context of individual entities, models, and applications. Capturing the context requires having a thorough understanding of what the entity, model, or application was intended to do and is able to do. While many aspects of context are not easily expressible in a format or language that could be understood and managed in a simulation environment, there are some aspects that can be and the authors discuss how these aspects can be represented in a generalized object-oriented framework.

Hummel, J. R.; Christiansen, J. H.

2000-02-16T23:59:59.000Z

223

Urethane anesthesia blocks the development and expression of kindled seizures  

SciTech Connect (OSTI)

The effect of anesthetic and subanesthetic doses of urethane on the development of amygdala kindled seizures and on the expression of previously kindled seizures was studied in hooded rats. An anesthetic dose of urethane almost completely eliminated evoked after discharge and completely eliminated convulsive behavior in both groups. It also eliminated the seizure response to pentylenetetrazol. Subanesthetic doses of urethane strongly attenuated the expression of previously kindled seizures. These results suggest that urethane may not be an appropriate anesthetic for the study of epileptiform phenomena.

Cain, D.P.; Raithby, A.; Corcoran, M.E.

1989-01-01T23:59:59.000Z

224

Phase-plane visualizations of gestural structure in expressive timing  

E-Print Network [OSTI]

, and describe the construction of the phase-plane representa- tion from the time series using a functional has been one of the major topics in music perfor- mance research. As an expressive parameter, timing is used to clarify the musical structure of the piece (Clarke, 1988), among other things. Background

Widmer, Gerhard

225

Genome Function and Nuclear Architecture: From Gene Expression to Nanoscience  

E-Print Network [OSTI]

Genome Function and Nuclear Architecture: From Gene Expression to Nanoscience Timothy P. O'Brien,1, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold, and nanoscience to relate genome organization and nuclear archi- tecture with development and disease. Integrating

Langowski, Jörg

226

Abstract Interpretation with Alien Expressions and Heap Structures  

E-Print Network [OSTI]

Abstract Interpretation with Alien Expressions and Heap Structures Bor-Yuh Evan Chang0, and K constraint mentions other, alien, function or relation symbols, it is ignored (that is, it is very coarsely over-approximated) by the abstract domain. Rather than building in special treatment of such alien

Leino, K. Rustan M.

227

Monday, March 13, 2006 MARS EXPRESS: PROBING THE DEPTHS  

E-Print Network [OSTI]

. Plaut J. J. Observations of the "Stealth" Radar Feature in the Mars Express MARSIS Investigation [#1946] We will present the latest observations of the "Stealth" radar feature by the MARSIS radar. 9:30 a and Plains materials in Gusev, complementing in situ Spirit observations. 10:15 a.m. Bibring J.-P. * Langevin

Rathbun, Julie A.

228

Pim-1 kinase expression during murine mammary development  

SciTech Connect (OSTI)

Pim-1 kinase phosphorylates substrates whose activities are linked to proliferation, survival, differentiation, and apoptosis. Although pim-1 is induced by hormones and cytokines, the hormonal control and contribution of Pim-1 to mammary gland development have not been evaluated. We examined Pim-1 expression in mammary cell lines, investigated whether Pim-1 levels could be altered in breast epithelia by mammogenic hormones, and evaluated Pim-1 expression during mammary development. We found that Pim-1 was elevated in most mammary carcinoma cell lines and progesterone increased Pim-1 protein to some extent in non-tumorigenic mammary epithelia. Pim-1 expression in situ was consistent with the documented profile of progesterone activity in mouse mammary glands. Pim-1 nuclear localization correlated with cytoplasmic distribution for its substrate, p21{sup CIP/Waf1}, and we found that Pim-1 and p21 associate in vitro. Our results suggest that Pim-1 expression may be regulated by progesterone during mammary development and Pim-1 associates with p21 in mammary epithelial cells.

Gapter, Leslie A. [Department of Pharmacy, Faculty of Science, National University of Singapore, 117543 (Singapore); School of Molecular Biosciences, Washington State University, Pullman, WA 99164-4234 (United States); Magnuson, Nancy S. [School of Molecular Biosciences, Washington State University, Pullman, WA 99164-4234 (United States); Ng, Ka-yun [Department of Pharmacy, Faculty of Science, National University of Singapore, 117543 (Singapore); Hosick, Howard L. [School of Molecular Biosciences, Washington State University, Pullman, WA 99164-4234 (United States)]. E-mail: hosick@wsu.edu

2006-07-07T23:59:59.000Z

229

A Brief History of the Freedom of Expressions  

E-Print Network [OSTI]

for zero. · Decimal numerals. · Calculation easier. Brahmagupta #12;Solving quadratics (820) Muhammad ibnA Brief History of the Freedom of Expressions Matt Might http://matt.might.net/ #12;Sapir) #12;Limits on the Greeks · No notation for zero. · No variables for unknowns. · No symbols

Might, Matt

230

Hormonal regulation of microRNA expression in the ovary  

E-Print Network [OSTI]

forms of gene regulation, including post-transcriptional gene regulation. One mechanism of post-transcriptional gene regulation is the expression and function of microRNA (miRNA). These highly conserved, short, non-coding RNA molecules primarily silence...

Luense, Lacey J.

2012-12-31T23:59:59.000Z

231

Symbolic Discriminant Analysis for Mining Gene Expression Patterns Jason Moore  

E-Print Network [OSTI]

multivariate statistical approach for classification of observations into groups because the theory is wellSymbolic Discriminant Analysis for Mining Gene Expression Patterns Jason Moore Vanderbilt: Leukemia Jason H. Moore, Joel S. Parker, Lance W. Hahn Linear discriminant analysis is a popular

Fernandez, Thomas

232

NANO EXPRESS Open Access Multiscale investigation of graphene layers on  

E-Print Network [OSTI]

NANO EXPRESS Open Access Multiscale investigation of graphene layers on 6H-SiC(000-1) Antoine , Cecile Naud2 , Jean-Yves Veuillen2* Abstract In this article, a multiscale investigation of few graphene, the authors show that the UHV growth yields few layer graphene (FLG) with an average thickness given by Auger

Paris-Sud XI, Université de

233

ANALYSIS OF GENE EXPRESSION PROFILES AND DRUG ACTIVITY PATTERNS BY  

E-Print Network [OSTI]

are more related to the kind of cancer than to drug activity patterns. Dependency analysis using Bayesian1 11 ANALYSIS OF GENE EXPRESSION PROFILES AND DRUG ACTIVITY PATTERNS BY CLUSTERING AND BAYESIAN of data produced from up- to-date biological experimental processes needs appropriate data mining

234

Elevated Fis Expression Enhances Recombinant Protein Production in  

E-Print Network [OSTI]

Elevated Fis Expression Enhances Recombinant Protein Production in Escherichia coli Richard Richins is discussed. A small DNA bending protein, Fis, which has been shown to activate rRNA syn- thesis upon a nutrient upshift, was overexpressed in E. coli strain W3110 carrying vector pUCR1. Overexpres- sion of Fis

Chen, Wilfred

235

New Expressions for Level-restricted Kostka Polynomials  

E-Print Network [OSTI]

consider the two generalizations together giving rise to level- restricted generalized Kostka polynomials KNew Expressions for Level-restricted Kostka Polynomials Anne Schilling 1 and Mark Shimozono 2 ? 1 to level-restriction. In particular we give an explicit characteriza- tion of the image of level

Schilling, Anne

236

ORIGINAL ARTICLE Regulation of nif gene expression and the  

E-Print Network [OSTI]

ORIGINAL ARTICLE Regulation of nif gene expression and the energetics of N2 fixation over the diel importance in biogeochemical cycling of nitrogen. We analyzed the levels of nif transcripts of Synechococcus ecotypes, NifH subunit and nitrogenase activity over the diel cycle in the microbial mat of an alkaline hot

237

MICROFLUIDIC DEVICES FOR GENENTIC ANAYLSIS AND GENE EXPRESSION STUDIES  

E-Print Network [OSTI]

MICROFLUIDIC DEVICES FOR GENENTIC ANAYLSIS AND GENE EXPRESSION STUDIES Thesis by Jian Liu field of microfluidics. His advice has helped me out many times when I was struggling in my research, Ziyang Ma, Emil Kartalov, and many other colleagues. I thank Dr. Jessica Melin and the microfluidic

Quake, Stephen R.

238

Plasticity of opsin gene expression in cichlids from Lake Malawi  

E-Print Network [OSTI]

Plasticity of opsin gene expression in cichlids from Lake Malawi CHRISTOPHER M. HOFMANN, KELLY E. O plasticity has important evolutionary implications. In this study, we examined retinal plasticity in five found that the magnitude of plasticity varied across species. These findings have important implications

Carleton, Karen L.

239

Inflammatory Gene Expression in Goats in Response to Transport  

E-Print Network [OSTI]

was to determine whether expression of immune-related genes changes in goats that are exposed to transport stress. In this study, 15 Spanish-Boer goats ranging from 3 to 4 yrs of age were transported for 12 h. Goats were divided into 5 groups of 3 and placed in 1...

Carter, Mark

2012-10-19T23:59:59.000Z

240

Expressing Default Abduction Problems as Quantified Boolean Formulas  

E-Print Network [OSTI]

1 Expressing Default Abduction Problems as Quantified Boolean Formulas Hans Tompits Institut f@kr.tuwien.ac.at Abduction is the process of finding explanations for observed phenomena in accord to known laws about, we deal with a model for abduction in which the domain knowledge is represented in terms of a default

Tompits, Hans

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While these samples are representative of the content of NLEBeta,
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We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

EXPRESSING COLLABORATION AND COMPETITION AMONG ABDUCTIVE LOGIC AGENTS  

E-Print Network [OSTI]

EXPRESSING COLLABORATION AND COMPETITION AMONG ABDUCTIVE LOGIC AGENTS Anna Ciampolini, Evelina a language for coordinating several logic­based agents capable of abductive reasoning. The system to guess the causes of some symptoms. In his respect, some form of open or abductive reasoning has

Torroni, Paolo

242

EPAC expression and function in cardiac fibroblasts and myofibroblasts  

SciTech Connect (OSTI)

In the heart, cardiac fibroblasts (CF) and cardiac myofibroblasts (CMF) are the main cells responsible for wound healing after cardiac insult. Exchange protein activated by cAMP (EPAC) is a downstream effector of cAMP, and it has been not completely studied on CF. Moreover, in CMF, which are the main cells responsible for cardiac healing, EPAC expression and function are unknown. We evaluated in both CF and CMF the effect of transforming growth factor ?1 (TGF-?1) on EPAC-1 expression. We also studied the EPAC involvement on collagen synthesis, adhesion, migration and collagen gel contraction. Method: Rat neonatal CF and CMF were treated with TGF-?1 at different times and concentrations. EPAC-1 protein levels and Rap1 activation were measured by western blot and pull down assay respectively. EPAC cellular functions were determined by adhesion, migration and collagen gel contraction assay; and collagen expression was determined by western blot. Results: TGF-?1 through Smad and JNK significantly reduced EPAC-1 expression in CF, while in CMF this cytokine increased EPAC-1 expression through ERK1/2, JNK, p38, AKT and Smad3. EPAC activation was able to induce higher Rap1-GTP levels in CMF than in CF. EPAC and PKA, both cAMP effectors, promoted CF and CMF adhesion on fibronectin, as well as CF migration; however, this effect was not observed in CMF. EPAC but not PKA activation mediated collagen gel contraction in CF, while in CMF both PKA and EPAC mediated collagen gel contraction. Finally, the EPAC and PKA activation reduced collagen synthesis in CF and CMF. Conclusion: TGF-?1 differentially regulates the expression of EPAC in CF and CMF; and EPAC regulates differentially CF and CMF functions associated with cardiac remodeling. - Highlights: • TGF-?1 regulates EPAC-1 expression in cardiac fibroblast and myofibroblast. • Rap-1GTP levels are higher in cardiac myofibroblast than fibroblast. • EPAC-1 controls adhesion, migration and collagen synthesis in cardiac fibroblast. • PKA regulates collagen gel contraction in cardiac myofibroblast.

Olmedo, Ivonne; Muñoz, Claudia; Guzmán, Nancy; Catalán, Mabel; Vivar, Raúl; Ayala, Pedro; Humeres, Claudio; Aránguiz, Pablo [Departamento de Química Farmacológica y Toxicológica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile (Chile); García, Lorena [Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile (Chile); Velarde, Victoria [Departamento de Ciencias Fisiológicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile (Chile); Díaz-Araya, Guillermo, E-mail: gadiaz@ciq.uchile.cl [Departamento de Química Farmacológica y Toxicológica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile (Chile)

2013-10-15T23:59:59.000Z

243

Ann. Rev. Physiol. 1978. 400:447-69 Copyright O 1978 by Annual Reviews Inn. AN righrs reserved  

E-Print Network [OSTI]

. Maximal levels of oxygen consumption have been elicited by electrically stimulating animals with low of oxygen consumption during activity, emphasizing maximal oxygen consumption; aerobic scope; the cost metabolism of vertebrates historically has concen- trated on determination of standard or basal metabolism

Bennett, Albert F.

244

Speaking the unspeakable: emotional expressions of identity within journals  

E-Print Network [OSTI]

expression of feelings and experiences for personal clarification and understanding, these journals offer something different. With authorization from family members, several entries have been read publicly, revealing Robert?s desire to have his diaries... and shared, public narratives is the notion of expectations. There are no specific expectations to fulfill within journal writing, except for those maintained by the author, unlike the social expectations that guide human interaction and communication...

Horrocks, Aubrie

2004-11-15T23:59:59.000Z

245

DLM Early Childhood Express: Assessment in Early Childhood  

E-Print Network [OSTI]

DLM Early Childhood Express Assessment in Early Childhood Dr. Rafael Lara-Alecio a-lara@neo.tamu.edu Dr. Beverly J. Irby edu_bid@shsu.edu What principles guide assessment for effectively improving student learning? ? Assessment is inherently... a process of professional judgment. ? Assessment is based on separate but related principles of measurement evidence and evaluation. ? Assessment decision-making is influenced by a series of tensions. ? Assessment influences student motivation...

Lara-Alecio, Rafael; Irby, Beverly J.

2010-10-22T23:59:59.000Z

246

Heterocyst Morphogenesis and Gene Expression in Anabaena sp. PCC 7120  

E-Print Network [OSTI]

experiments we found that conR (all0187) gene is necessary for normal septum-formation of vegetative cells, diazotrophic grow, and heterocyst morphogenesis. In our studies we characterized the expression of sigma factors genes in Anabaena PCC 7120 during... are developmentally regulated................... 15 Heterocyst pattern formation requires dynamic signaling............................ 17 II Anabaena SP. STRAIN PCC 7120 GENE conR (ALL0187) CONTAINS A LytR-CpsA-Psr DOMAIN, IS DEVELOPMENTALLY REGULATED...

Mella Herrera, Rodrigo Andres

2010-10-12T23:59:59.000Z

247

MicroRNA expression in canine mammary cancer  

E-Print Network [OSTI]

to act as both tumor suppressors and oncogenes in several different cancers, expression patterns of ten miRNAs (miR-15a, miR-16, miR-17-5p, miR-21, miR-29b, miR-125b, miR-145, miR-155, miR-181b, let-7f) known to be associated with human breast cancer were...

Boggs, Rene' Michelle

2008-10-10T23:59:59.000Z

248

Genetic and expression analysis of enabled in Drosophila leg segmentation  

E-Print Network [OSTI]

the UAS/GAL4 (Brand and Perrimon, 1993) system gives rise to tarsal segment fusions (Buckles et al. , in preparation). The fusion phenotype is not observed when a form of Abl lacking the kinase activity is over-expressed, hence the kinase function... tested for dominant enhancement of the GOF ab/ fusion phenotype. Seventeen interacting loci were recovered: one copy of the deficiency in that sensitized background was sufficient to give a leg phenotype (tarsal segment fusion, ectopic joints, shorter...

Ramel, Marie-Christine

2012-06-07T23:59:59.000Z

249

Bitumen fume-induced gene expression profile in rat lung  

SciTech Connect (OSTI)

Exposure to bitumen fumes during paving and roofing activities may represent an occupational health risk. To date, most of the studies performed on the biological effect of asphalt fumes have been done with regard to their content in carcinogenic polycyclic aromatic hydrocarbons (PAH). In order to gain an additional insight into the mechanisms of action of bitumen fumes, we studied their pulmonary effects in rodents following inhalation using the microarray technology. Fisher 344 rats were exposed for 5 days, 6 h/day to bitumen fumes generated at road paving temperature (170 {sup o}C) using a nose-only exposition device. With the intention of studying the early transcriptional events induced by asphalt fumes, lung tissues were collected immediately following exposure and gene expression profiles in control and exposed rats were determined by using oligonucleotide microarrays. Data analysis revealed that genes involved in lung inflammatory response as well as genes associated with PAH metabolization and detoxification were highly expressed in bitumen-exposed animals. In addition, the expression of genes related to elastase activity and its inhibition which are associated with emphysema was also modulated. More interestingly genes coding for monoamine oxidases A and B involved in the metabolism of neurotransmitters and xenobiotics were downregulated in exposed rats. Altogether, these data give additional information concerning the bitumen fumes biological effects and would allow to better review the health effects of occupational asphalt fumes exposure.

Gate, Laurent [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France)]. E-mail: laurent.gate@inrs.fr; Langlais, Cristina [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France); Micillino, Jean-Claude [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France); Nunge, Herve [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France); Bottin, Marie-Claire [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France); Wrobel, Richard [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France); Binet, Stephane [Institut National de Recherche et Securite, Avenue de Bourgogne, BP 27, 54501 Vandoeuvre Cedex (France)

2006-08-15T23:59:59.000Z

250

Imaging gene expression in real-time using aptamers  

SciTech Connect (OSTI)

Signal transduction pathways are usually activated by external stimuli and are transient. The downstream changes such as transcription of the activated genes are also transient. Real-time detection of promoter activity is useful for understanding changes in gene expression, especially during cell differentiation and in development. A simple and reliable method for viewing gene expression in real time is not yet available. Reporter proteins such as fluorescent proteins and luciferase allow for non-invasive detection of the products of gene expression in living cells. However, current reporter systems do not provide for real-time imaging of promoter activity in living cells. This is because of the long time period after transcription required for fluorescent protein synthesis and maturation. We have developed an RNA reporter system for imaging in real-time to detect changes in promoter activity as they occur. The RNA reporter uses strings of RNA aptamers that constitute IMAGEtags (Intracellular MultiAptamer GEnetic tags), which can be expressed from a promoter of choice. The tobramycin, neomycin and PDC RNA aptamers have been utilized for this system and expressed in yeast from the GAL1 promoter. The IMAGEtag RNA kinetics were quantified by RT-qPCR. In yeast precultured in raffinose containing media the GAL1 promoter responded faster than in yeast precultured in glucose containing media. IMAGEtag RNA has relatively short half-life (5.5 min) in yeast. For imaging, the yeast cells are incubated with their ligands that are labeled with fluorescent dyes. To increase signal to noise, ligands have been separately conjugated with the FRET (Förster resonance energy transfer) pairs, Cy3 and Cy5. With these constructs, the transcribed aptamers can be imaged after activation of the promoter by galactose. FRET was confirmed with three different approaches, which were sensitized emission, acceptor photobleaching and donor lifetime by FLIM (fluorescence lifetime imaging microscopy). Real-time transcription was measured by FLIM-FRET, which was detected by the decrease in donor lifetime resulting from ligand binding to IMAGEtags that were newly synthesized from the activated GAL1 promoter. The FRET signal was specific for transcribed IMAGEtags.

Shin, Il Chung

2011-12-13T23:59:59.000Z

251

The body parametric : abstraction of vocal and physical expression in performance  

E-Print Network [OSTI]

Performing artists have frequently used technology to sense and extend the body's natural expressivity via live control of multimedia. However, the sophistication, emotional content, and variety of expression possible ...

Nattinger, Elena Jessop

2014-01-01T23:59:59.000Z

252

E-Print Network 3.0 - affecting mrna expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

search results for: affecting mrna expression Page: << < 1 2 3 4 5 > >> 1 Molecular Biology 311 Problem Set 5 Answers Summary: in the expression of calcitonin mRNA in the...

253

E-Print Network 3.0 - altered mrna expression Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

search results for: altered mrna expression Page: << < 1 2 3 4 5 > >> 1 Molecular Biology 311 Problem Set 5 Answers Summary: in the expression of calcitonin mRNA in the...

254

E-Print Network 3.0 - activate mrna expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

search results for: activate mrna expression Page: << < 1 2 3 4 5 > >> 1 Molecular Biology 311 Problem Set 5 Answers Summary: in the expression of calcitonin mRNA in the...

255

E-Print Network 3.0 - acbp gene expression Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

acbp gene expression Search Powered by Explorit Topic List Advanced Search Sample search results for: acbp gene expression Page: << < 1 2 3 4 5 > >> 1 Membrane Charge and Curvature...

256

E-Print Network 3.0 - auxin-regulated gene expression Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

regulated gene expression Search Powered by Explorit Topic List Advanced Search Sample search results for: auxin-regulated gene expression Page: << < 1 2 3 4 5 > >> 1 Funct Integr...

257

E-Print Network 3.0 - aldose reductase expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

is NR1, which appears widely expressed in human cancer cell lines and could... , Stricker O, Bohme H, Gomez- Moreno C, Peleato ML. Expression of ferredoxin-NADP1 reductase...

258

E-Print Network 3.0 - aromatase mrna expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

mrna expression Page: << < 1 2 3 4 5 > >> 1 ORIGINAL ARTICLE Aromatase mRNA in the Brain of Adult Green Anole Lizards: Effects of Summary: activity and mRNA expression in...

259

Using Plan Recognition for Interpreting Referring Expressions Dustin A. Smith and Henry Lieberman  

E-Print Network [OSTI]

Using Plan Recognition for Interpreting Referring Expressions Dustin A. Smith and Henry Lieberman MIT Media Lab 20 Ames St. Cambridge, MA 02139 Abstract Referring expressions such as "a long meeting

Lieberman, Henry

260

Photo of the Week: An Express Train to Crescent Junction | Department...  

Broader source: Energy.gov (indexed) [DOE]

An Express Train to Crescent Junction Photo of the Week: An Express Train to Crescent Junction January 4, 2013 - 1:53pm Addthis In the 1950s, one of the largest uranium deposits in...

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Division of Human Resources University Grievance Procedures  

E-Print Network [OSTI]

Division of Human Resources University Grievance Procedures Employee Relations/ USF System Grievance Procedure Questions: (813) 974-2970 Rev. 12/2012 This procedure applies to Administration, Staff in this procedure are expressed in calendar days. If a deadline falls on a Saturday, Sunday or holiday, an action

Meyers, Steven D.

262

Refining GAL4-Driven Transgene Expression in Drosophila With a GAL80 Enhancer-Trap  

E-Print Network [OSTI]

LETTER Refining GAL4-Driven Transgene Expression in Drosophila With a GAL80 Enhancer-trap element, P{GAL80}, that encodes the yeast GAL80 repressor to refine expression of transgenes driven neurons. This line was used to refine GFP expression from a set of over 200 neurons to a subset of 20

Sokolowski, Marla

263

Determining the effect of LEF-12 on late viral gene expression  

E-Print Network [OSTI]

and improve upon the baculovirus expression system. The most recently identified LEF, LEF-12, was found to be necessary for transient late gene expression but its function has yet to be determined (5). We over-expressed and purified the LEF-12 protein...

Peterson, April Lynn

2013-02-22T23:59:59.000Z

264

A Model of Gene Expression and Regulation in an Artificial Cellular Organism  

E-Print Network [OSTI]

expression and regulation based on the operon model of Jacob and Monod. Operons are groups of genes regulated and complexity of gene expression in real cells and it should also bear close relationships to EC so that it can, Jacob and Monod developed the operon model of gene expression and regulation [1, 5, 7] to explain

Fernandez, Thomas

265

Expression and rearrangement of the ROS1 gene in human glioblastoma cells  

SciTech Connect (OSTI)

The human ROS1 gene, which possibly encodes a growth factor receptor, was found to be expressed in human tumor cell lines. In a survey of 45 different human cell lines, the authors found ROS1 to be expressed in glioblastoma-derived cell lines at high levels and not to be expressed at all, or expressed at very low levels, in the remaining cell lines. The ROS1 gene was present in normal copy numbers in all cell lines that expressed the gene. However, in one particular glioblastoma line, they detected a potentially activating mutation at the ROS1 locus.

Birchmeier, C.; Sharma, S.; Wigler, M.

1987-12-01T23:59:59.000Z

266

Advanced radioisotope power source options for Pluto Express  

SciTech Connect (OSTI)

In the drive to reduce mass and cost, Pluto Express is investigating using an advanced power conversion technology in a small Radioisotope Power Source (RPS) to deliver the required mission power of 74 W(electric) at end of mission. Until this year the baseline power source under consideration has been a Radioisotope Thermoelectric Generator (RTG). This RTG would be a scaled down GPHS RTG with an inventory of 6 General Purpose Heat Sources (GPHS) and a mass of 17.8 kg. High efficiency, advanced technology conversion options are being examined to lower the power source mass and to reduce the amount of radioisotope needed. Three technologies are being considered as the advanced converter technology: the Alkali Metal Thermal-to-Electric Converter (AMTEC), Thermophotovoltaic (TPV) converters, and Stirling Engines. Conceptual designs for each of these options have been prepared. Each converter would require only 2 GPHSs to provide the mission power and would have a mass of 6.1, 7.2, and 12.4 kg for AMTEC, TPV, and Stirling Engines respectively. This paper reviews the status of each technology and the projected performance of an advanced RPS based on each technology. Based on the projected performance and spacecraft integration issues, Pluto Express would prefer to use the AMTEC based RPS. However, in addition to technical performance, selection of a power technology will be based on many other factors.

Underwood, M.L. [California Inst. of Technology, Pasadena, CA (United States). Jet Propulsion Lab.

1995-12-31T23:59:59.000Z

267

MEASURING AND EXPRESSING THE PERFORMANCE OF ENERGY STORAGE SYSTEMS  

SciTech Connect (OSTI)

Until late 2012, there was no uniform methodology to measure and express the performance of energy storage systems (ESS). A void in this area can affect the acceptance of ESS in the marketplace because different systems cannot be equitably compared and ESS cost-benefit analysis may be challenging due to a lack of verified and relevant ESS performance. The lack of such criteria also furthers the probability that each ESS customer or user will make up their own; necessitating “custom validation” to a unique set of criteria each time an ESS is to be considered or installed. To address this need and foster the acceptance of ESS, the U.S. Department of Energy’s (DOE) Energy Storage Systems Program facilitated the development of a protocol to measure and express ESS performance and is supporting its updating, enhancement and use in formal consensus standards development. Of particular interest is the development of the document through an open and transparent process that saved considerable time.

Schoenwald, David; Conover, David R.

2013-12-03T23:59:59.000Z

268

There are no classes or examinations on Bank Holidays (4 and 25 Mid-Semester Study Period (First Semester)  

E-Print Network [OSTI]

.3 SCHOOL COMMUNICATION The main Reception Area in the Alan Turing Building is just inside the main entrance fortnightly and important messages are displayed on the OneLan Screen in the foyer of the Alan Turing Building. There are student notice boards in the Alan Turing Building on the walls inside the Mathematics Undergraduate Work

Glendinning, Paul

269

Evaluation of fracture risk and potential drug holidays for postmenopausal women on long-term bisphosphonate therapy  

E-Print Network [OSTI]

Study objective: To describe characteristics of postmenopausal women on long-term bisphosphonate therapy who fall into one of four fracture risk categories (low, mild, moderate, high), and to determine the prevalence of women eligible for a drug...

Kostoff, Matthew D.; Saseen, Joseph J.; Borgelt, Laura M.

2014-04-28T23:59:59.000Z

270

OPEN 4:30p.m. 1:00a.m. daily (except University holidays)  

E-Print Network [OSTI]

: Italian, Ranch, Blue Cheese, Balsamic, Caesar Extra Dressing $ .59 6- piece Sushi $5.39 Fresh Fruit $ . 72-Broccoli Tomato Basil Veggie White Chicken Bacon Ranch Your choice of White or Whole Wheat Crust Hot Sandwiches.69 Chicken Caesar Salad $5.89 Chef Salad $5.89 All salads come with one dressing packet. Choice of Dressings

McConnell, Terry

271

Estimated Savings from Turning Off Unnecessary Lights at the Langford Architecture Center During the 1996 Christmas Holidays  

E-Print Network [OSTI]

lights been left on, the building would have consumed 100 kW more electricity every hour. The total electricity savings was about 31,200 kWh over 13 days, which is equivalent to a total cost saving of $936.00. If the College continues to turn off...

Soebarto, V. I.; Haberl, J. S.; Degelman, L. O.

1997-01-01T23:59:59.000Z

272

Travel Reminder The holiday season is a hectic time for international travel. Airports, consulates and ports of entry are  

E-Print Network [OSTI]

and ports of entry are extremely busy due to the large number of travelers and increased security measures passports at most ports of entry as part of the increased security measures effective under the Western

Oklahoma, University of

273

San Antonio HolidayFeaturing 4 Nights in San Antonio December 4-8, 2013 (5 days)  

E-Print Network [OSTI]

Day 4: LBJ Ranch - Fredericksburg - Luminarias Today travel to the Hill Country of Texas and take Antonio. Later wander the Riverwalk to experience the Fiesta de las Luminarias, which features thousands ·Riverwalk Cruise ·Hill Country ·LBJ Ranch ·Fredericksburg ·Fiesta de las Luminarias ·4 Nights at One Hotel

274

A graphical environment to express the semantics of control systems  

E-Print Network [OSTI]

We present the concept of a unified graphical environment for expressing the semantics of control systems. The graphical control system design environment in Simulink already allows engineers to insert a variety of assertions aimed the verification and validation of the control software. We propose extensions to a Simulink-like environment's annotation capabilities to include formal control system stability, performance properties and their proofs. We provide a conceptual description of a tool, that takes in a Simulink-like diagram of the control system as the input, and generates a graphically annotated control system diagram as the output. The annotations can either be inserted by the user or generated automatically by a third party control analysis software such as IQC$\\beta$ or $\\mu$-tool. We finally describe how the graphical representation of the system and its properties can be translated to annotated programs in a programming language used in verification and validation such as Lustre or C.

Wang, Timothy; Feron, E

2011-01-01T23:59:59.000Z

275

Circadian oscillation of starch branching enzyme gene expression in the sorghum endosperm  

SciTech Connect (OSTI)

Expression of the three SBE genes, encoding starch branching enzymes, in the sorghum endosperm exhibited a diurnal rhythm during a 24-h cycle. Remarkably, the oscillation in SBE expression was maintained in cultured spikes after a 48-h dark treatment, also when fed a continuous solution of sucrose or abscisic acid. Our findings suggest that the rhythmicity in SBE expression in the endosperm is independent of cues from the photosynthetic source and that the oscillator resides within the endosperm itself.

Mutisya, J.; Sun, C.; Jansson, C.

2009-08-31T23:59:59.000Z

276

E-Print Network 3.0 - amplified metallothionein expression Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

1991). The increased... expression may be favored in environments exposed to heavy metal pollution over recent human history (Lange Source: Hartl, Daniel L. - Department of...

277

E-Print Network 3.0 - anger expression violent Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

fear) while others by facial expression (anger and happiness) DeSilva97 Better performance and more... subject Neutral state Anger Sadness Happiness 102 Markers to track...

278

E-Print Network 3.0 - alpha7 integrin-expressing myoblasts Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

rat skeletal myoblasts expressed N... (Eckert and Schnackerz, 1991; Wolff and Stiller, 1993). Second, skeletal myoblasts might establish Source: Murry, Chuck - Center for...

279

Expression of Ligands for the NKG2D Activating Receptor are Linked to Proliferative Signals  

E-Print Network [OSTI]

UV stress post-translationally induced expression of one NKG2D ligand in mice, Mult1, by inhibiting ubiquition-dependent degradation

Jung, Heiyoun

2011-01-01T23:59:59.000Z

280

E-Print Network 3.0 - approaches gene expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

D: Knowledge Questions 1. You are investigating the changes in gene expression in cancer cells compared to normal cells Summary: Appendix D: Knowledge Questions 1. You are...

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

E-Print Network 3.0 - altered neuronatin expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

in hypothalamus (neuronatin, transcript variant 1), striatum (PPP1R1B, FLJ20940 fis) and choroid... Proceedings Analysis of multiplex gene expression maps obtained by...

282

Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks  

E-Print Network [OSTI]

connectivity would lead to information loss. The adjacencygene co-expression information and, leads to results thatgenes does not lead to major information loss for the key

Carlson, Marc R J; Zhang, Bin; Fang, Zixing; Mischel, Paul S; Horvath, Steve; Nelson, Stanley F

2006-01-01T23:59:59.000Z

283

E-Print Network 3.0 - adenovirus-mediated sflk-1 expression Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

gene transfer and expression by prior depletion... -148. 6. Freytag SO, Stricker H, Pegg J, et al. Phase I study of replication- competent adenovirus-mediated... . Li...

284

E-Print Network 3.0 - adiponectin gene expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the AMPK pathway for the treatment of Type 2 diabetes Summary: enhance the expression and secretion of adiponectin in humans19 and rodents and , through the activation... complexes...

285

E-Print Network 3.0 - assisted mechanical expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Powered by Explorit Topic List Advanced Search Sample search results for: assisted mechanical expression Page: << < 1 2 3 4 5 > >> 1 Mechanical Engineering Department WORCESTER...

286

E-Print Network 3.0 - a2 peroxidase expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

., Cereghino, G.P.L. & Gold, M.H. (1999) Homologous expression of recombinant lignin peroxidase... of bee venom phos- pholipase A2. Biochemistry 24, ... Source: Youngs,...

287

T cells stimulate catabolic gene expression by the stromal cells from giant cell tumor of bone  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Two T cell lines stimulate PTHrP, RANKL, MMP13 gene expression in GCT cell cultures. Black-Right-Pointing-Pointer CD40 expressed by stromal cells; CD40L detected in whole tumor but not cultures. Black-Right-Pointing-Pointer Effect of CD40L treatment on GCT cells increased PTHrP and MMP13 gene expression. Black-Right-Pointing-Pointer PTHrP treatment increased MMP13 expression, while inhibition decreased expression. Black-Right-Pointing-Pointer T cells may stimulate GCT stromal cells and promote the osteolysis of the tumor. -- Abstract: The factors that promote the localized bone resorption by giant cell tumor of bone (GCT) are not fully understood. We investigated whether T cells could contribute to bone resorption by stimulating expression of genes for parathyroid hormone-related protein (PTHrP), matrix metalloproteinase (MMP)-13, and the receptor activator of nuclear-factor {kappa}B ligand (RANKL). Two cell lines, Jurkat clone E6-1 and D1.1, were co-cultured with isolated GCT stromal cells. Real-time PCR analyses demonstrated a significant increase of all three genes following 48 h incubation, and PTHrP and MMP-13 gene expression was also increased at 24 h. Further, we examined the expression of CD40 ligand (CD40L), a protein expressed by activated T cells, and its receptor, CD40, in GCT. Immunohistochemistry results revealed expression of the CD40 receptor in both the stromal cells and giant cells of the tumor. RNA collected from whole GCT tissues showed expression of CD40LG, which was absent in cultured stromal cells, and suggests that CD40L is expressed within GCT. Stimulation of GCT stromal cells with CD40L significantly increased expression of the PTHrP and MMP-13 genes. Moreover, we show that inhibition of PTHrP with neutralizing antibodies significantly decreased MMP13 expression by the stromal cells compared to IgG-matched controls, whereas stimulation with PTHrP (1-34) increased MMP-13 gene expression. These results suggest that T cells may potentiate the catabolic effect of GCT.

Cowan, Robert W. [Department of Pathology and Molecular Medicine, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L8 (Canada) [Department of Pathology and Molecular Medicine, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L8 (Canada); Juravinski Cancer Centre, 699 Concession St., Hamilton, ON, Canada L8V 5C2 (Canada); Ghert, Michelle [Juravinski Cancer Centre, 699 Concession St., Hamilton, ON, Canada L8V 5C2 (Canada) [Juravinski Cancer Centre, 699 Concession St., Hamilton, ON, Canada L8V 5C2 (Canada); Department of Surgery, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L8 (Canada); Singh, Gurmit, E-mail: gurmit.singh@jcc.hhsc.ca [Department of Pathology and Molecular Medicine, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L8 (Canada) [Department of Pathology and Molecular Medicine, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L8 (Canada); Juravinski Cancer Centre, 699 Concession St., Hamilton, ON, Canada L8V 5C2 (Canada)

2012-03-23T23:59:59.000Z

288

Factory Express a New Mexico Service Disabled Veteran-Owned Company  

E-Print Network [OSTI]

Factory Express a New Mexico Service Disabled Veteran-Owned Company ... a New Mexico small business the company.'" Factory Express is the exclusive provider in New Mexico of service and sales for the type Kirtland Air Force Base in Albuquerque, New Mexico. Office size? Small. Staff size? Small. Budget? Small

289

Expressing and computing passage time measures of GSPN models with HASL  

E-Print Network [OSTI]

Expressing and computing passage time measures of GSPN models with HASL Elvio Gilberto Amparore1 measures in (Tagged) GSPNs using the Hybrid Automata Stochastic Logic (HASL) and the statistical model), formally express them in HASL terms and assess them by means of simulation in the COSMOS tool. The interest

Paris-Sud XI, Université de

290

Expression of a Tensor Commutation Matrix in Terms of the Generalized Gell-Mann Matrices  

E-Print Network [OSTI]

We have expressed the tensor commutation matrix n\\otimes n as linear combination of the tensor products of the generalized Gell-Mann matrices. The tensor commutation matrices 3\\otimes 2 and 2\\otimes 3 have been expressed in terms of the classical Gell-Mann matrices and the Pauli matrices.

Rakotonirina Christian

2005-11-21T23:59:59.000Z

291

Design and implementation of an expressive gesture model for a humanoid robot  

E-Print Network [OSTI]

as robot joint values and sent to the robot in order to execute the hand-arm movements. The robot hasDesign and implementation of an expressive gesture model for a humanoid robot Quoc Anh Le Telecom-- We aim at equipping the humanoid robot NAO with the capacity of performing expressive communicative

Paris-Sud XI, Université de

292

The orphan nuclear receptor Nur77 regulates decidual prolactin expression in human endometrial stromal cells  

SciTech Connect (OSTI)

Research highlights: {yields} Decidually produced PRL plays a key role during pregnancy. {yields} Overexpression of Nur77 increased PRL mRNA expression and enhanced decidual PRL promoter activity. {yields} Knockdown of Nur77 decreased decidual PRL secretion induced by 8-Br-cAMP and MPA. {yields} Nur77 is a novel transcription factor that plays an active role in decidual prolactin expression. -- Abstract: Prolactin (PRL) is synthesized and released by several extrapituitary tissues, including decidualized stromal cells. Despite the important role of decidual PRL during pregnancy, little is understood about the factors involved in the proper regulation of decidual PRL expression. Here we present evidence that the transcription factor Nur77 plays an active role in decidual prolactin expression in human endometrial stromal cells (hESCs). Nur77 mRNA expression in hESCs was significantly increased after decidualization stimulated by 8-Br-cAMP and medroxyprogesterone acetate (MPA). Adenovirus-mediated overexpression of Nur77 in hESCs markedly increased PRL mRNA expression and enhanced decidual PRL promoter (dPRL/-332Luc) activity in a concentration-dependent manner. Furthermore, knockdown of Nur77 in hESCs significantly decreased decidual PRL promoter activation and substantially attenuated PRL mRNA expression and PRL secretion (P < 0.01) induced by 8-Br-cAMP and MPA. These results demonstrate that Nur77 is a novel transcription factor that contributes significantly to the regulation of prolactin gene expression in human endometrial stromal cells.

Jiang, Yue; Hu, Yali; Zhao, Jing; Zhen, Xin [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)] [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China); Yan, Guijun, E-mail: yanguijun33@gmail.com [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)] [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China); Sun, Haixiang, E-mail: stevensunz@163.com [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)] [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)

2011-01-14T23:59:59.000Z

293

Large density fluctuations in the martian ionosphere as observed by the Mars Express radar sounder  

E-Print Network [OSTI]

in the martian ionosphere. The density measurements show a persistent level of large fluctuations, sometimesLarge density fluctuations in the martian ionosphere as observed by the Mars Express radar sounder Advanced Radar for Subsurface and Ionosphere Sounding) instrument on the Mars Express spacecraft provides

Gurnett, Donald A.

294

Practical expressions for the internal energy and pressure of Yukawa fluids  

E-Print Network [OSTI]

Simple practical expressions are put forward, which allow to estimate thermodynamic properties of Yukawa fluids in a wide range of coupling, up to the fluid-solid phase transition. These expressions demonstrate excellent agreement with the available results from numerical simulations. The approach provides simple and accurate tool to estimate thermodynamic properties of Yukawa fluids and related systems in a broad range of parameters.

Khrapak, Sergey

2015-01-01T23:59:59.000Z

295

Dartmouth College Computer Science Technical Report TR2004-503 Enhancing Expressiveness of Speech  

E-Print Network [OSTI]

Dartmouth College Computer Science Technical Report TR2004-503 Enhancing Expressiveness of Speech for expressiveness. When text is entered into the program, the Festival Text-to-Speech engine creates a speech file be obtained for speech dictated into a microphone using Microsoft SAPI and the CSLU Toolkit. Once lip

296

THE "AIR WORM": AN INTERFACE FOR REAL-TIME MANIPULATION OF EXPRESSIVE MUSIC PERFORMANCE  

E-Print Network [OSTI]

THE "AIR WORM": AN INTERFACE FOR REAL-TIME MANIPULATION OF EXPRESSIVE MUSIC PERFORMANCE Simon Dixon of Computational Perception Johannes Kepler University, Linz, Austria ABSTRACT Expressive performance file. Several modes of operation are possible: the "Air Worm" builds on previous work in performance vi

Widmer, Gerhard

297

Gene expression divergence and nucleotide differentiation between males of different color morphs and mating  

E-Print Network [OSTI]

Gene expression divergence and nucleotide differentiation between males of different color morphs sequencing, it is possible to obtain data on both nucleotide sequence variation and gene expression. We have between males, but many genetic markers showed nucleotide differentiation between different color morphs

298

Expression of Phospholipases A2 and C in Human Corneal Epithelial Cells  

E-Print Network [OSTI]

-healing pro- cesses in human corneal epithelial cells (HCECs), expression of phospholipase A2s (PLA2s for RT-PCR amplifi- cation of the known secreted (s)PLA2, cytosolic (c)PLA2, and PLC mRNAs. Corresponding and Western blot analyses were used to detect the PLA2s and PLCs expressed by HCECs. RESULTS. The m

Gelb, Michael

299

Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated  

E-Print Network [OSTI]

secretion of milk­lipid droplets Sherry L. Ogg*, Anne K. Weldon*, Lorraine Dobbie , Andrew J. H. Smith expressed in the lactating mammary gland and is secreted into milk in association with lipid droplets expression of Btn1a1 was either disrupted or eliminated, respectively. The regulated secretion of milk­lipid

Mather, Ian

300

Microfluidic single cell real-time PCR for comparative analysis of gene expression patterns  

E-Print Network [OSTI]

Microfluidic single cell real-time PCR for comparative analysis of gene expression patterns collection. We present here a high-content microfluidic real-time platform as a powerful tool expression; dynamic assay; microfluidic; pluripotent INTRODUCTION Novel genomic technologies have paved

Quake, Stephen R.

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Phenotypic plasticity in opsin expression in a butterfly compound eye complements sex role  

E-Print Network [OSTI]

Phenotypic plasticity in opsin expression in a butterfly compound eye complements sex role reversal-2148/12/232 #12;RESEARCH ARTICLE Open Access Phenotypic plasticity in opsin expression in a butterfly compound eye* Abstract Background: Animals often display phenotypic plasticity in morphologies and behaviors that result

Monteiro, Antónia

302

ETUDE DE L'EXPRESSION DES KINASES AURORA DANS LE CARCINOME A CELLULES RENALES  

E-Print Network [OSTI]

ETUDE DE L'EXPRESSION DES KINASES AURORA DANS LE CARCINOME A CELLULES RENALES Romain Mathieu rénales, kinases Aurora, thérapies ciblées, envahissement ganglionnaire Nombre de mots total : 2092 Nombre OF THE EXPRESSION OF AURORA KINASES IN RENAL CELL CARCINOMA Romain Mathieu(a), Jean-Jacques Patard(a,b), Nathalie

Paris-Sud XI, Université de

303

A novel copper-regulated promoter system for expression of heterologous proteins in Schizosaccharomyces pombe  

E-Print Network [OSTI]

A novel copper-regulated promoter system for expression of heterologous proteins the promoter of the ctr41 copper transporter gene from S. pombe, we created a series of vectors, named pctr41 -X, which regulate the expression of heterologous genes as a function of copper availability

Labbé, Simon

304

Early Embryonic Expression of Ion Channels and Pumps in Chick and Xenopus Development  

E-Print Network [OSTI]

Early Embryonic Expression of Ion Channels and Pumps in Chick and Xenopus Development JOSHUA during embryonic morphogenesis. Al- though the expression of ion channel and pump genes, which on the distribution and function of specific channels and pumps in early embryogenesis. To provide a necessary basis

Levin, Michael

305

Expression of an Arabidopsis vacuolar -pyrophosphatase gene (AVP1) in cotton improves  

E-Print Network [OSTI]

Expression of an Arabidopsis vacuolar H+ -pyrophosphatase gene (AVP1) in cotton improves drought, pro- ton pump, root development, salt stress, transgenic cotton. Summary The Arabidopsis gene AVP1 conditions. Using the same approach, AVP1-expressing cotton plants were created and tested

Blumwald, Eduardo

306

Expression of an Arabidopsis vacuolar -pyrophosphatase gene (AVP1) in cotton improves  

E-Print Network [OSTI]

Expression of an Arabidopsis vacuolar H+ -pyrophosphatase gene (AVP1) in cotton improves drought- ton pump, root development, salt stress, transgenic cotton. Summary The Arabidopsis gene AVP1 encodes-expressing cotton plants were created and tested for their performance under high-salt and reduced irrigation

Blumwald, Eduardo

307

Identification and Characterization of Bovine Pol III Promoters to Express a Short-Hairpin RNA  

E-Print Network [OSTI]

RNA expression sequence in the lentiviral vector pNef-GT. A transient luciferase knockdown assay in human embryonic kidney (HEK) 293T cells was used to compare the functionality of these vectors. The bPol III mir30 shRNA expression vector was co...

Peoples, Michael D 1978-

2010-12-08T23:59:59.000Z

308

954ER4 Specification 4 ports RS-232 PCI-Express Serial cards  

E-Print Network [OSTI]

954ER4 Specification 4 ports RS-232 PCI-Express Serial cards FEATURES 4 independent RS-232 serial ports with communication speeds up to 230 921 ­­­­Kbps Designed to meet PCI-Express Base Specification PC system. Majority of today's motherboard no longer come with serial ports or only have one port

Berns, Hans-Gerd

309

Differential expression of nanog1 and nanogp8 in colon cancer cells  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Nanog is expressed in a majority of colon cancer cell lines examined. Black-Right-Pointing-Pointer Both nanog1 and nanogp8 are expressed in colon cancer cells with varying ratios. Black-Right-Pointing-Pointer Nanog mediates cell proliferation of colon cancer cells. Black-Right-Pointing-Pointer Nanog predominantly localizes in cytoplasm of colon cancer cells. -- Abstract: Nanog, a homeodomain transcription factor, is an essential regulator for promotion of self-renewal of embryonic stem cells and inhibition of their differentiation. It has been demonstrated that nanog1 as well as nanogp8, a retrogene of nanog1, is preferentially expressed in advanced stages of several types of cancer, suggesting their involvement during cancer progression. Here, we investigated the expression of Nanog in well-characterized colon cancer cell lines. Expression of Nanog was detectable in 5 (HCT116, HT29, RKO, SW48, SW620) out of seven cell lines examined. RNA expression analyses of nanog1 and nanogp8 indicated that, while nanog1 was a major form in SW620 as well as in teratoma cells Tera-2, nanogp8 was preferentially expressed in HT29 and HCT116. In accordance with this, shRNA-mediated knockdown of nanog1 caused the reduction of Nanog in SW620 but not in HT29. Inhibition of Nanog in SW620 cells negatively affected cell proliferation and tumor formation in mouse xenograft. Biochemical subcellular fractionation and immunostaining analyses revealed predominant localization of Nanog in cytoplasm in SW620 and HT29, while it was mainly localized in nucleus in Tera-2. Our data indicate that nanog1 and nanogp8 are differentially expressed in colon cancer cells, and suggest that their expression contributes to proliferation of colon cancer cells.

Ishiguro, Tatsuya; Sato, Ai; Ohata, Hirokazu; Sakai, Hiroaki [Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan)] [Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan); Nakagama, Hitoshi, E-mail: hnakagam@ncc.go.jp [Division of Cancer Development System, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan)] [Division of Cancer Development System, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan); Okamoto, Koji, E-mail: kojokamo@ncc.go.jo [Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan)] [Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 (Japan)

2012-02-10T23:59:59.000Z

310

Gene expression profiling in Ishikawa cells: A fingerprint for estrogen active compounds  

SciTech Connect (OSTI)

Several anthropogenous and naturally occurring substances, referred to as estrogen active compounds (EACs), are able to interfere with hormone and in particular estrogen receptor signaling. EACs can either cause adverse health effects in humans and wildlife populations or have beneficial effects on estrogen-dependent diseases. The aim of this study was to examine global gene expression profiles in estrogen receptor (ER)-proficient Ishikawa plus and ER-deficient Ishikawa minus endometrial cancer cells treated with selected well-known EACs (Diethylstilbestrol, Genistein, Zearalenone, Resveratrol, Bisphenol A and o,p'-DDT). We also investigated the effect of the pure antiestrogen ICI 182,780 (ICI) on the expression patterns caused by these compounds. Transcript levels were quantified 24 h after compound treatment using Illumina BeadChip Arrays. We identified 87 genes with similar expression changes in response to all EAC treatments in Ishikawa plus. ICI lowered the magnitude or reversed the expression of these genes, indicating ER dependent regulation. Apart from estrogenic gene regulation, Bisphenol A, o,p'-DDT, Zearalenone, Genistein and Resveratrol displayed similarities to ICI in their expression patterns, suggesting mixed estrogenic/antiestrogenic properties. In particular, the predominant antiestrogenic expression response of Resveratrol could be clearly distinguished from the other test compounds, indicating a distinct mechanism of action. Divergent gene expression patterns of the phytoestrogens, as well as weaker estrogenic gene expression regulation determined for the anthropogenous chemicals Bisphenol A and o,p'-DDT, warrants a careful assessment of potential detrimental and/or beneficial effects of EACs. The characteristic expression fingerprints and the identified subset of putative marker genes can be used for screening chemicals with an unknown mode of action and for predicting their potential to exert endocrine disrupting effects.

Boehme, Kathleen; Simon, Stephanie [Merck KGaA, Merck Serono, NCD/Toxicology, Early and Explanatory Toxicology, 64271 Darmstadt (Germany); Mueller, Stefan O. [Merck KGaA, Merck Serono, NCD/Toxicology, Early and Explanatory Toxicology, 64271 Darmstadt (Germany)], E-mail: stefan.o.mueller@merck.de

2009-04-01T23:59:59.000Z

311

Sex-based differences in gene expression in hippocampus following postnatal lead exposure  

SciTech Connect (OSTI)

The influence of sex as an effect modifier of childhood lead poisoning has received little systematic attention. Considering the paucity of information available concerning the interactive effects of lead and sex on the brain, the current study examined the interactive effects of lead and sex on gene expression patterns in the hippocampus, a structure involved in learning and memory. Male or female rats were fed either 1500 ppm lead-containing chow or control chow for 30 days beginning at weaning.Blood lead levels were 26.7 {+-} 2.1 {mu}g/dl and 27.1 {+-} 1.7 {mu}g/dl for females and males, respectively. The expression of 175 unique genes was differentially regulated between control male and female rats. A total of 167 unique genes were differentially expressed in response to lead in either males or females. Lead exposure had a significant effect without a significant difference between male and female responses in 77 of these genes. In another set of 71 genes, there were significant differences in male vs. female response. A third set of 30 genes was differentially expressed in opposite directions in males vs. females, with the majority of genes expressed at a lower level in females than in males. Highly differentially expressed genes in males and females following lead exposure were associated with diverse biological pathways and functions. These results show that a brief exposure to lead produced significant changes in expression of a variety of genes in the hippocampus and that the response of the brain to a given lead exposure may vary depending on sex. - Highlights: > Postnatal lead exposure has a significant effect on hippocampal gene expression patterns. > At least one set of genes was affected in opposite directions in males and females. > Differentially expressed genes were associated with diverse biological pathways.

Schneider, J.S., E-mail: jay.schneider@jefferson.edu; Anderson, D.W.; Sonnenahalli, H.; Vadigepalli, R.

2011-10-15T23:59:59.000Z

312

Ethanol increases matrix metalloproteinase-12 expression via NADPH oxidase-dependent ROS production in macrophages  

SciTech Connect (OSTI)

Matrix metalloproteinase-12 (MMP-12), an enzyme responsible for degradation of extracellular matrix, plays an important role in the progression of various diseases, including inflammation and fibrosis. Although most of those are pathogenic conditions induced by ethanol ingestion, the effect of ethanol on MMP-12 has not been explored. In the present study, we investigated the effect of ethanol on MMP-12 expression and its potential mechanisms in macrophages. Here, we demonstrated that ethanol treatment increased MMP-12 expression in primary murine peritoneal macrophages and RAW 264.7 macrophages at both mRNA and protein levels. Ethanol treatment also significantly increased the activity of nicotinamide adenine dinucleotide (NADPH) oxidase and the expression of NADPH oxidase-2 (Nox2). Pretreatment with an anti-oxidant (N-acetyl cysteine) or a selective inhibitor of NADPH oxidase (diphenyleneiodonium chloride (DPI)) prevented ethanol-induced MMP-12 expression. Furthermore, knockdown of Nox2 by small interfering RNA (siRNA) prevented ethanol-induced ROS production and MMP-12 expression in RAW 264.7 macrophages, indicating a critical role for Nox2 in ethanol-induced intracellular ROS production and MMP-12 expression in macrophages. We also showed that ethanol-induced Nox2 expression was suppressed by transient transfection with dominant negative I?B-? plasmid or pretreatment with Bay 11-7082, a selective inhibitor of NF-?B, in RAW 264.7 macrophages. In addition, ethanol-induced Nox2 expression was also attenuated by treatment with a selective inhibitor of p38 MAPK, suggesting involvement of p38 MAPK/NF-?B pathway in ethanol-induced Nox2 expression. Taken together, these results demonstrate that ethanol treatment elicited increase in MMP-12 expression via increase in ROS production derived from Nox2 in macrophages. - Highlights: • Ethanol increases ROS production through up-regulation of Nox2 in macrophages. • Enhanced oxidative stress contributes to ethanol-induced MMP-12 expression. • p38 MAPK/NF-?B signaling pathway modulates ethanol-induced Nox2 expression.

Kim, Mi Jin; Nepal, Saroj; Lee, Eung-Seok; Jeong, Tae Cheon [College of Pharmacy, Yeungnam University, Gyeongsanbuk-do 712-749 (Korea, Republic of); Kim, Sang-Hyun [Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu 700-422 (Korea, Republic of); Park, Pil-Hoon, E-mail: parkp@yu.ac.kr [College of Pharmacy, Yeungnam University, Gyeongsanbuk-do 712-749 (Korea, Republic of)

2013-11-15T23:59:59.000Z

313

RNA binding protein and binding site useful for expression of recombinant molecules  

DOE Patents [OSTI]

The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.

Mayfield, Stephen P.

2006-10-17T23:59:59.000Z

314

RNA binding protein and binding site useful for expression of recombinant molecules  

DOE Patents [OSTI]

The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.

Mayfield, Stephen (Cardiff, CA)

2000-01-01T23:59:59.000Z

315

Over Expression of the CMP-sialic Acid Transporter in Chinese Hamster Ovary Cells Leads to Increased Sialylation  

E-Print Network [OSTI]

Most glyco-engineering approaches used to improve quality of recombinant glycoproteins involve the manipulation of glycosyltransferase and/or glycosidase expression. We investigated whether the over expression of nucleotide ...

Wong, Niki S.C.

316

Systematic analysis of the role of differential expression of microRNAs associated with cell death decisions  

E-Print Network [OSTI]

The link between abnormal microRNA expression and cancer has been widely reported. However, little is known about the relationships between temporal microRNA expression and changes in cell behavior. To better understand ...

Guillén, Nancy, Ph. D. Massachusetts Institute of Technology

2014-01-01T23:59:59.000Z

317

A homeotic gene expression map in the central nervous system of larval Drosophila melanogaster: a quest for the holy engrailed  

E-Print Network [OSTI]

. In this study cellular maps of the expression of the homeotic gene engrailed within the thoracic ventral ganglion of Drosophila larvae were created. Additionally, a staining technique used to label both engrailed expressing cells and dividing neuroblasts within...

Evers, Bret Michael

2013-02-22T23:59:59.000Z

318

Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production  

E-Print Network [OSTI]

We studied changes in chondrocyte gene expression, aggrecan degradation, and aggrecanase production and activity in normal and mechanically injured cartilage co-cultured with joint capsule tissue. Chondrocyte expression ...

Grodzinsky, Alan J.

319

New trends in protein expression In order to benefit from the wealth of genomics data and to  

E-Print Network [OSTI]

systems. These include parallel construct design, new and more robust expression systems, modifications to support the pressing requirements of the research pipeline. However, protein expression is not only to the expres- sion constructs, introduction of new and/or improved prokaryotic and eukaryotic expression

Sussman, Joel L.

320

Expression of Stromal-Derived Factor-1 Is Decreased by IL-1 and TNF and in Dermal Wound Healing1  

E-Print Network [OSTI]

A. Springer2 * Stromal-derived factor-1 (SDF-1) is a CXC chemokine that is believed fibroblasts and vessels of noninflamed tissues express SDF-1. Unexpectedly, we found that expression of SDF-1 is regulated by inflammation. Expression of SDF-1 by primary cultures of human gingival fibroblasts is potently

Springer, Timothy A.

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Microbial metatranscriptomics : towards understanding microbial gene expression and regulation in natural habitats  

E-Print Network [OSTI]

Metagenomic research has paved the way for a comprehensive understanding of the microbial gene parts list in nature, but a full understanding of microbial gene expression, regulation, and ecology remains a challenge. In ...

Shi, Yanmei, Ph. D. Massachusetts Institute of Technology

2011-01-01T23:59:59.000Z

322

Differential Expression of CD148 on leucocyte subsets in inflammatory arthritis  

E-Print Network [OSTI]

collagen- induced arthritis (CIA) [39,45] was studied. Eachstudies of CD148 in CIA joint tis- sue were performed. Inprotein expression was elevated in CIA joint tissues, and

2013-01-01T23:59:59.000Z

323

E-Print Network 3.0 - auxin-induced wus expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

results for: auxin-induced wus expression Page: << < 1 2 3 4 5 > >> 1 GENETICS AND GENOMICS WUS and STM-based reporter genes for studying meristem Summary: with the promoter of...

324

Tests of the coupled expression of latex and cardenolide plant defense in common milkweed (Asclepias syriaca)  

E-Print Network [OSTI]

Most plants have an incredible diversity of defensive traits (Duffey and Stout 1996, Agrawal and Fishbein 2006, Gaquerel et al. 2010). Hy- potheses for the expression of multiple defensive v www

Agrawal, Anurag

325

An Evolutionarily Conserved Enhancer Regulates Bmp4 Expression in Developing Incisor and Limb Bud  

E-Print Network [OSTI]

To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified ...

Jumlongras, Dolrudee

326

How community is expressed in place : spatial manifestations of two parishes  

E-Print Network [OSTI]

I believe that we become human only through contact with one another, and I am interested in our architectural expression and accommodation of our life in communities specifically communities larger than the family and ...

Macy, Christine

1985-01-01T23:59:59.000Z

327

Model-Based Face Tracking for View-Independent Facial Expression Recognition  

E-Print Network [OSTI]

and Previous work In search for the "perfect" human-machine interface, many computer vision researchers have 2D feature tracker for the recognition of three emotional expressions. In [14], Lien et al. use

Tomasi, Carlo

328

Phenotype Analysis of Tobacco Lines Expressing a Deregulated Arabidopsis Ca-ATPase (ACA2)  

E-Print Network [OSTI]

accumulation and bioavailability in transgenic plants accompanied increased activity of the deregulated vacuolar Ca / H antiporter CAX1 (Cation Exchanger 1) termed sCAX1. In this study, transgenic tobacco plants expressing deregulated Ca transporters...

Thompson, Sean

2012-02-14T23:59:59.000Z

329

E-Print Network 3.0 - age-dependent gene expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

search results for: age-dependent gene expression Page: << < 1 2 3 4 5 > >> 1 Current Biology, Vol. 12, 712723, April 30, 2002, 2002 Elsevier Science Ltd. All rights reserved. PII...

330

2014 EXPRESSIVE ROBOTICS Beall Center Camp Registration Form FOR AGES 14 19 years  

E-Print Network [OSTI]

2014 EXPRESSIVE ROBOTICS Beall Center Camp Registration Form FOR AGES 14 19 years Robotics is a twoweek middle/high school aged summer intensive focused on the development of robotic

Loudon, Catherine

331

Impact of the introduction of an express transit service in Waterloo Region  

E-Print Network [OSTI]

Impact of the introduction of an express transit service in Waterloo Region By Bruce Hellinga, Jeff Casello and Samira Farahani Proceedings of the ITE Canadian District Annual Conference held May 6-10, 2007

Hellinga, Bruce

332

apoptosis-related protein expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

22 23 24 25 Next Page Last Page Topic Index 141 Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression CiteSeer Summary: Acrolein is a...

333

U-116: IBM Tivoli Provisioning Manager Express for Software Distribution Multiple Vulnerabilities  

Broader source: Energy.gov [DOE]

Multiple vulnerabilities have been reported in IBM Tivoli Provisioning Manager Express for Software Distribution, which can be exploited by malicious people to conduct SQL injection attacks and compromise a user's system

334

E-Print Network 3.0 - atomic states expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary: atomicity. I will then express these notions in the static context in terms of program dependences... 244 6 245 7 246 8 248 5 249 6 250 7 251 8 Figure 3:...

335

NANO EXPRESS A Study on Field Emission Characteristics of Planar Graphene  

E-Print Network [OSTI]

NANO EXPRESS A Study on Field Emission Characteristics of Planar Graphene Layers Obtained from on field emission characteristics of individual graphene layers for vacuum nanoelectronics. Graphene layers enabled electric con- nection with the graphene layers without postfabrication. The maximum emitted

Yang, Eui-Hyeok

336

E-Print Network 3.0 - aberrant gene expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

interpreted... the patterns of expression of the aberrations as a function of time post-irradiation were not identical in both... of 12;48 B. Ponnaiya et al. Mutation Research...

337

A study of mammalian microRNA-mediated repression of gene expression by ribosome profiling  

E-Print Network [OSTI]

All cells in a multicellular organism carry the same genes, yet these same genes direct the differentiation of many different cell types. This is facilitated by differential gene expression, the control of which can be ...

Guo, Huili

2011-01-01T23:59:59.000Z

338

Extensive changes in DNA methylation are associated with expression of mutant huntingtin  

E-Print Network [OSTI]

The earliest stages of Huntington disease are marked by changes in gene expression that are caused in an indirect and poorly understood manner by polyglutamine expansions in the huntingtin (HTT) protein. To explore the ...

Ng, Christopher W.

339

E-Print Network 3.0 - aromatase gene expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

gene expression Page: << < 1 2 3 4 5 > >> 1 ORIGINAL ARTICLE Aromatase mRNA in the Brain of Adult Green Anole Lizards: Effects of Summary: of testosterone to oestradiol (E2)...

340

Examination of dioxin and its alteration of gene expression via DNA Microarray Analysis  

E-Print Network [OSTI]

), and ADD/ADHD. Little evidence has been available to demonstrate how dioxin specifically alters gene expression, both in developing embryos and adults. Recently, Texas A&M University has acquired several DNA Microarray Systems, which are revolutionizing...

Wright, Justin Charles

2013-02-22T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

E-Print Network 3.0 - angiotensinogen mrna expression Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3 Outline Plasma Membrane Summary: -25 Gene Expression Genes are lengths of DNA that code for synthesis of RNA mRNA carries info for how... occurs when mRNA sequence is used...

342

Inferring interactions, expression programs and regulatory networks from high throughput biological data  

E-Print Network [OSTI]

(cont.) For the networks level I present an algorithm that efficiently combines complementary large-scale expression and protein-DNA binding data to discover co-regulated modules of genes. This algorithm is extended so ...

Bar-Joseph, Ziv, 1971-

2003-01-01T23:59:59.000Z

343

E-Print Network 3.0 - anhydrase ix expression Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

ix expression Page: << < 1 2 3 4 5 > >> 1 Prokaryotic carbonic anhydrases Kerry S. Smith *, James G. Ferry Summary: , growth inhibition by cyanate of a cynS deletion strain...

344

Gene Expression and Association Analyses of Stress Responses in Loblolly Pine (Pinus taeda L.)  

E-Print Network [OSTI]

The molecular mechanisms underlying disease-resistance and drought-resistance in forest trees are not well understood. Linking variation in gene expression with genetic polymorphisms and with variations in disease- and drought-resistance phenotypes...

Seeve, Candace Marie

2012-02-14T23:59:59.000Z

345

Genomic Analysis of Parent-of-Origin Allelic Expression in Arabidopsis thaliana Seeds  

E-Print Network [OSTI]

Differential expression of maternally and paternally inherited alleles of a gene is referred to as gene imprinting, a form of epigenetic gene regulation common to flowering plants and mammals. In plants, imprinting primarily ...

Gehring, Mary

346

E-Print Network 3.0 - alters hepatic expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Explorit Topic List Advanced Search Sample search results for: alters hepatic expression Page: << < 1 2 3 4 5 > >> 1 How Hepatitis D Virus Can Hinder the Control of Hepatitis B...

347

Design criteria for purposefully ambiguous expression : proposal for a theater / performing arts school in Kenmore Square  

E-Print Network [OSTI]

Inclusion of zones which possess sufficient ambiguity to provide multiple use, character and meaning, generating an environment supporting freedom of interpretation and expression, is explored in this thesis. Conceptually, ...

Verhulst, Catharina A

1986-01-01T23:59:59.000Z

348

Heterogeneity of tumor-induced gene expression changes in the human metabolic network  

E-Print Network [OSTI]

Reprogramming of cellular metabolism is an emerging hallmark of neoplastic transformation. However, it is not known how the expression of metabolic genes in tumors differs from that in normal tissues, or whether different ...

Hu, Jie

349

Kiss1 Gene Expression and the Effects of Kisspeptin During Pubertal Development in the Ewe Lamb  

E-Print Network [OSTI]

puberty. In Experiment 1, ovariectomized ewe lambs bearing subcutaneous estradiol implants were used to investigate Kiss1 gene expression in the preoptic area (POA) and hypothalamus during pubertal maturation of the reproductive neuroendocrine system...

Redmond, Jeremy Scott

2012-02-14T23:59:59.000Z

350

Sublethal Oxygen–Glucose Deprivation Alters Hippocampal Neuronal AMPA Receptor Expression and Vulnerability to  

E-Print Network [OSTI]

Recent studies have suggested that rats subjected to transient global brain ischemia develop depressed expression of GluR-B in CA1 hippocampal neurons. The present study was performed to determine whether a similar change in AMPA receptor expression could be triggered in vitro by sublethal oxygen–glucose deprivation in rat hippocampal neuronal cultures. mRNA was extracted from individual hippocampal neurons via patch electrodes and amplified by RT-PCR 24–48 hr after sublethal oxygen–glucose deprivation. Compared with controls, insulted neurons expressed increased levels of GluR-D flop. As an indication that this change in receptor expression was functionally significant, insulted cultures exhibited increased AMPA- or kainate-induced 45 Ca 2 ? accumulation sensitive to Joro spider toxin and increased vulnerability to kainate-induced death. These data support the hypothesis that exposure to ischemia may enhance subsequent hippocampal

Kainate-induced Death; Howard S. Ying; Jochen H. Weishaupt; Margaret Grabb; Lorella M. T. Canzoniero; Stefano L. Sensi; Christian T. Sheline; Hannah Monyer; Dennis W. Choi

351

E-Print Network 3.0 - anaerobic gene expression Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Medicine 15 Proc. Natl. Acad. Sci. USA Vol. 93, pp. 3575-3580, April 1996 Summary: and environmental regulation of nitro- genase gene expression and enzyme activity would expand...

352

Biomedical data retrieval utilizing textual data in a gene expression database by Richard Lu, MD.  

E-Print Network [OSTI]

Background: The commoditization of high-throughput gene expression sequencing and microarrays has led to a proliferation in both the amount of genomic and clinical data that is available. Descriptive textual information ...

Lu, Richard, M.D

2010-01-01T23:59:59.000Z

353

TABASCO: A single molecule, base-pair resolved gene expression simulator  

E-Print Network [OSTI]

Background Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavior. Given our current understanding of gene ...

Kosuri, Sriram

354

Systematic analysis of gene expression in human brains before and after death  

E-Print Network [OSTI]

substantially Table 2 Functional analysis of gene expression differences between autopsy and resection samples GO ID Term Expressed genes Significant differences* Change p value Conservation p value GO:0006412 Protein biosynthesis 462 101 (37/64) 0.001 0.999 GO... functional processes. Genes involved in rather basic functions, such as RNA processing, protein bio- synthesis and transport, organelle organization and biogen- esis, the ubiquitin cycle, and DNA repair (Table 1) are over- represented among genes differently...

Franz, Henriette; Ullmann, Claudia; Becker, Albert; Ryan, Margaret; Bahn, Sabine; Arendt, Thomas; Simon, Matthias; Paabo, Svante; Khaitovich, Philipp

2005-12-30T23:59:59.000Z

355

Effects of dietary fiber and carcinogen on fatty acid binding protein expression in exfoliated colonocytes  

E-Print Network [OSTI]

EFFECTS OF DIETARY FIBER AND CARCINOGEN ON FATTY ACID BINDING PROTEIN EXPRESSION IN EXFOLIATED COLONOCYTES A Thesis by AMY EUNICE CLARK Submitted to the Office of Gmduate Studies of Texas A&M University in partial fulfillment...) Bryan H. Johnson (Head of Department) August 1997 Major Subject: Nutrition ABSTRACT Effects of Dietary Fiber and Carcinogen on Fatty Acid Binding Protein Expression in Exfoliated Colonocytes. (August 1997) Amy Eunice Clark, B. S. , Texas A...

Clark, Amy Eunice

1997-01-01T23:59:59.000Z

356

Expression and characterization of human group V phospholipase A2 Yijun Chen, Edward A. Dennis *  

E-Print Network [OSTI]

phospholipase A2 (GV-PLA2) has been shown to be involved in signal transduction and inflammatory processes. We report the over-expression and characterization of GV-PLA2. The GV-PLA2 cDNA was synthesized from human heart polyA mRNA by RT-PCR, and an expression construct containing the GV-PLA2 was established

Dennis, Edward A.

357

Radiation-Induced Micro-RNA Expression Changes in Peripheral Blood Cells of Radiotherapy Patients  

SciTech Connect (OSTI)

Purpose: MicroRNAs (miRNAs), a class of noncoding small RNAs that regulate gene expression, are involved in numerous physiologic processes in normal and malignant cells. Our in vivo study measured miRNA and gene expression changes in human blood cells in response to ionizing radiation, to develop miRNA signatures that can be used as biomarkers for radiation exposure. Methods and Materials: Blood from 8 radiotherapy patients in complete remission 1 or 2 was collected immediately before and 4 hours after total body irradiation with 1.25 Gy x-rays. Both miRNA and gene expression changes were measured by means of quantitative polymerase chain reaction and microarray hybridization, respectively. Hierarchic clustering, multidimensional scaling, class prediction, and gene ontology analysis were performed to investigate the potential of miRNAs to serve as radiation biomarkers and to elucidate their likely physiologic roles in the radiation response. Results: The expression levels of 45 miRNAs were statistically significantly upregulated 4 hours after irradiation with 1.25 Gy x-rays, 27 of them in every patient. Nonirradiated and irradiated samples form separate clusters in hierarchic clustering and multidimensional scaling. Out of 223 differentially expressed genes, 37 were both downregulated and predicted targets of the upregulated miRNAs. Paired and unpaired miRNA-based classifiers that we developed can predict the class membership of a sample with unknown irradiation status, with accuracies of 100% when all 45 upregulated miRNAs are included. Both miRNA control of and gene involvement in biologic processes such as hemopoiesis and the immune response are increased after irradiation, whereas metabolic processes are underrepresented among all differentially expressed genes and the genes controlled by miRNAs. Conclusions: Exposure to ionizing radiation leads to the upregulation of the expression of a considerable proportion of the human miRNAome of peripheral blood cells. These miRNA expression signatures can be used as biomarkers of radiation exposure.

Templin, Thomas; Paul, Sunirmal; Amundson, Sally A.; Young, Erik F. [Center for Radiological Research, Department of Radiation Oncology, Columbia University Medical Center, New York, NY (United States); Barker, Christopher A.; Wolden, Suzanne L. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Smilenov, Lubomir B., E-mail: lbs5@columbia.ed [Center for Radiological Research, Department of Radiation Oncology, Columbia University Medical Center, New York, NY (United States)

2011-06-01T23:59:59.000Z

358

Purification and expression of fatty acid binding proteins in chicken liver and intestine  

E-Print Network [OSTI]

PURIFICATION AND EXPRESSION OF FATTY ACID BINDING PROTEINS IN CHICKEN LIVER AND INTESTINE A Thesis by JULIA ELLEN SEWELL Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE August 1988 Major subject: Nutrition PURIFICATION AND EXPRESSION OF FATTY ACID BINDING PROTEINS IN CHICKEN LIVER AND INTESTINE A Thesis by JULIA ELLEN SEWELL Approved as to style and content by: Pamela S. Hargi (Chair of Committ...

Sewell, Julia Ellen

1988-01-01T23:59:59.000Z

359

Expression of PRL proteins at invasive margin of rectal cancers in relation to preoperative radiotherapy  

SciTech Connect (OSTI)

Purpose: PRL-3 (phosphatase of regenerating liver) is involved in metastasis of colorectal cancer; however, its therapeutic implication in cancer patients has not been studied. We investigated the relationships of PRL expression to radiotherapy (RT) in rectal cancer patients. Methods and Materials: Phosphatase of regenerating liver expression was immunohistochemically examined in distant (n = 36) and adjacent (n = 82) normal mucosa, primary tumor (n = 125), biopsy specimens (n = 96), and lymph node metastasis (n = 30) from rectal cancer patients participating in a clinical trial of preoperative RT. Results: Phosphatase of regenerating liver expression was increased from the distant to adjacent mucosa and to the primary tumor (p < 0.05). PRL was highly expressed at the invasive margin in 28% of the primary tumors and 26% of the metastases. In the RT group, strong PRL expression at the invasive margin was related to distant recurrence (p 0.006) and poor survival (p = 0.01), but not in the non-RT group. The survival significance remained even after adjusting for Dukes' stage and differentiation (p = 0.02). Additional multivariate analyses showed that the correlation with prognostic significance of PRL differed between the RT and non-RT groups (p = 0.01). Conclusion: Phosphatase of regenerating liver expression (rather than PRL-3 alone) at the invasive margin predicted resistance to RT and unfavorable survival in rectal cancer patients with preoperative RT.

Wallin, Asa R. [Department of Oncology, Institute of Biomedicine and Surgery, University of Linkoeping, Linkoeping (Sweden); Svanvik, Joar [Department of Surgery, Institute of Biomedicine and Surgery, University of Linkoeping, Linkoeping (Sweden); Adell, Gunnar [Department of Oncology, Institute of Biomedicine and Surgery, University of Linkoeping, Linkoeping (Sweden); Sun Xiaofeng [Department of Oncology, Institute of Biomedicine and Surgery, University of Linkoeping, Linkoeping (Sweden)]. E-mail: xiasu@ibk.liu.se

2006-06-01T23:59:59.000Z

360

Knockdown of p53 suppresses Nanog expression in embryonic stem cells  

SciTech Connect (OSTI)

Highlights: •We investigate the role of p53 in ESCs in the absence of DNA damage. •p53 knockdown suppresses ESC proliferation. •p53 knockdown downregulates Nanog expression. •p53 is essential for mouse ESC self-renewal. -- Abstract: Mouse embryonic stem cells (ESCs) express high levels of cytoplasmic p53. Exposure of mouse ESCs to DNA damage leads to activation of p53, inducing Nanog suppression. In contrast to earlier studies, we recently reported that chemical inhibition of p53 suppresses ESC proliferation. Here, we confirm that p53 signaling is involved in the maintenance of mouse ESC self-renewal. RNA interference-mediated knockdown of p53 induced downregulation of p21 and defects in ESC proliferation. Furthermore, p53 knockdown resulted in a significant downregulation in Nanog expression at 24 and 48 h post-transfection. p53 knockdown also caused a reduction in Oct4 expression at 48 h post-transfection. Conversely, exposure of ESCs to DNA damage caused a higher reduction of Nanog expression in control siRNA-treated cells than in p53 siRNA-treated cells. These data show that in the absence of DNA damage, p53 is required for the maintenance of mouse ESC self-renewal by regulating Nanog expression.

Abdelalim, Essam Mohamed, E-mail: emohamed@qf.org.qa [Qatar Biomedical Research Institute, Qatar Foundation, Doha 5825 (Qatar); Molecular Neuroscience Research Center, Shiga University of Medical Science, Setatsukinowa-cho, Otsu, Shiga 520-2192 (Japan); Department of Cytology and Histology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia (Egypt); Tooyama, Ikuo [Molecular Neuroscience Research Center, Shiga University of Medical Science, Setatsukinowa-cho, Otsu, Shiga 520-2192 (Japan)] [Molecular Neuroscience Research Center, Shiga University of Medical Science, Setatsukinowa-cho, Otsu, Shiga 520-2192 (Japan)

2014-01-10T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Rev-erb beta regulates the Srebp-1c promoter and mRNA expression in skeletal muscle cells  

SciTech Connect (OSTI)

The nuclear hormone receptor, Rev-erb beta operates as a transcriptional silencer. We previously demonstrated that exogenous expression of Rev-erb{beta}{Delta}E in skeletal muscle cells increased Srebp-1c mRNA expression. We validated these in vitro observations by injection of an expression vector driving Rev-erb{beta}{Delta}E expression into mouse tibialis muscle that resulted in increased Srebp-1c mRNA expression. Paradoxically, Rev-erb{beta} siRNA expression in skeletal muscle cells repressed Srebp-1c expression, and indicated that Rev-erb{beta} expression was necessary for Srebp-1c expression. ChIP analysis demonstrated that Rev-erb{beta} was recruited to the Srebp-1c promoter. Moreover, Rev-erb{beta} trans-activated the Srebp-1c promoter, in contrast, Rev-erb{beta} efficiently repressed the Rev-erb{alpha} promoter, a previously characterized target gene. Finally, treatment with the Rev-erb agonist (hemin) (i) increased the trans-activation of the Srebp-1c promoter by Rev-erb{beta}; and (ii) increased Rev-erb{beta} and Srebp-1c mRNA expression. These data suggest that Rev-erb{beta} has the potential to activate gene expression, and is a positive regulator of Srebp-1c, a regulator of lipogenesis.

Ramakrishnan, Sathiya N.; Lau, Patrick; Crowther, Lisa M. [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)] [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia); Cleasby, Mark E. [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia)] [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia); Millard, Susan; Leong, Gary M. [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)] [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia); Cooney, Gregory J. [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia)] [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia); Muscat, George E.O., E-mail: g.muscat@imb.uq.edu.au [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)

2009-10-30T23:59:59.000Z

362

Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration  

E-Print Network [OSTI]

DNA Variants Mediate Energy Production and Expression Levelsmediate not only energy production and cell growth, but alsoDNA Variants Mediate Energy Production and Expression Levels

2013-01-01T23:59:59.000Z

363

Aryl?hydrocarbon receptor activity modulates prolactin expression in the pituitary  

SciTech Connect (OSTI)

Pituitary tumors account for 15% of intracranial neoplasms, however the extent to which environmental toxicants contribute to the proliferation and hormone expression of pituitary cells is unknown. Aryl-hydrocarbon receptor (AhR) interacting protein (AIP) loss of function mutations cause somatotrope and lactotrope adenomas in humans. AIP sequesters AhR and inhibits its transcriptional function. Because of the link between AIP and pituitary tumors, we hypothesize that exposure to dioxins, potent exogenous ligands for AhR that are persistent in the environment, may predispose to pituitary dysfunction through activation of AhR. In the present study, we examined the effect of AhR activation on proliferation and endogenous pituitary hormone expression in the GH3 rat somatolactotrope tumor cell line and the effect of loss of AhR action in knockout mice. GH3 cells respond to nM doses of the reversible AhR agonist ?-naphthoflavone with a robust induction of Cyp1a1. Although mRNA levels of the anti-proliferative signaling cytokine TGFbeta1 are suppressed upon ?-naphthoflavone treatment, we did not observe an alteration in cell proliferation. AhR activation with ?-naphthoflavone suppresses Ahr expression and impairs expression of prolactin (PRL), but not growth hormone (GH) mRNA in GH3 cells. In mice, loss of Ahr similarly leads to a reduction in Prl mRNA at P3, while Gh is unaffected. Additionally, there is a significant reduction in pituitary hormones Lhb and Fshb in the absence of Ahr. Overall, these results demonstrate that AhR is important for pituitary hormone expression and suggest that environmental dioxins can exert endocrine disrupting effects at the pituitary. -- Highlights: ? AhR signaling suppresses Prl mRNA expression. ? AhR signaling does not influence pituitary proliferation in culture. ? AhR is necessary for Prl, Lhb and Fshb expression at postnatal day 3.

Moran, Tyler B.; Brannick, Katherine E.; Raetzman, Lori T., E-mail: raetzman@life.illinois.edu

2012-11-15T23:59:59.000Z

364

Investigating the Correspondence Between Transcriptomic and Proteomic Expression Profiles Using Coupled Cluster Models.  

SciTech Connect (OSTI)

Modern transcriptomics and proteomics enable us to survey the expression of RNAs and proteins at large scales. While these data are usually generated and analysed separately, there is an increasing interest in comparing and co-analysing transcriptome and proteome expression data. A major open question is whether transcriptome and proteome expression is linked and how it is coordinated. Results: Here we have developed a probabilistic clustering model that permits analysis of the links between transcriptomic and proteomic profiles in a sensible and flexible manner. Our coupled mixture model defines a prior probability distribution over the component to which a protein profile should be assigned conditioned on which component the associated mRNA profile belongs to. By providing probabilistic assignments this approach sits between the two extremes of concatenating the data on the assumption that mRNA and protein clusters would have a one-to-one relationship, and independent clustering where the mRNA profile provides no information on the protein profile and vice-versa. We apply this approach to a large dataset of quantitative transcriptomic and proteomic expression data obtained from a human breast epithelial cell line (HMEC) stimulated by epidermal growth factor (EGF) over a series of timepoints corresponding to one cell cycle. The results reveal a complex relationship between transcriptome and proteome with most mRNA clusters linked to at least two protein clusters, and vice versa. A more detailed analysis incorporating information on gene function from the gene ontology database shows that a high correlation of mRNA and protein expression is limited to the components of some molecular machines, such as the ribosome, cell adhesion complexes and the TCP-1 chaperonin involved in protein folding. Conclusions: The dynamic regulation of the transcriptome and proteome in mammalian cells in response to an acute mitogenic stimulus appears largely independent with very little correspondence between mRNA and protein expression. The exceptions involve a few selected multi-protein complexes that require the stoichiometric expression of components for correct function. This finding has wide ramifications regarding the understanding of gene and protein expression including its control and evolution. It also shows that transcriptomic and proteomic expression analysis are complementary and non-redundant.

Rogers, Simon; Girolami, Mark; Kolch, Walter; Waters, Katrina M.; Liu, Tao; Thrall, Brian D.; Wiley, H. S.

2008-12-01T23:59:59.000Z

365

Analysis of expressed sequence tags from a fetal human heart cDNA library  

SciTech Connect (OSTI)

Single-pass sequencing of randomly selected cDNA clones to generate expressed sequence tags (ESTs) has been widely used to identify novel genes and to study gene expression in a variety of tissues. We have generated 2244 ESTs from a human fetal heart library (Gen-Bank Accession Nos. R30692-30774 and R56965-58824), which we present in this report. Of these, 51.7% showed no homology to known genes or were similar only to other ESTs, while 48.4% demonstrated homology to known transcripts. A total of 764 ESTs corresponding to known genes were used to study gene expression patterns in the fetal heart and to analyze differences in these patterns from those observed in the adult heart. These analyses demonstrate the utility of ESTs and sequence-tagged clones in comparative studies of gene expression in the cardiovascular system, and they reveal that differential gene expression underlies the structural and functional characteristics of the developing heart. 48 refs., 1 fig., 3 tabs.

Hwang, D.M.; Fung, Y.W.; Wang, R.X.; Laurenssen, C.M. [Univ. of Toronto, Ontario (Canada)] [and others] [Univ. of Toronto, Ontario (Canada); and others

1995-11-20T23:59:59.000Z

366

Knowledge-based analysis of microarray gene expression data by using support vector machines  

SciTech Connect (OSTI)

The authors introduce a method of functionally classifying genes by using gene expression data from DNA microarray hybridization experiments. The method is based on the theory of support vector machines (SVMs). SVMs are considered a supervised computer learning method because they exploit prior knowledge of gene function to identify unknown genes of similar function from expression data. SVMs avoid several problems associated with unsupervised clustering methods, such as hierarchical clustering and self-organizing maps. SVMs have many mathematical features that make them attractive for gene expression analysis, including their flexibility in choosing a similarity function, sparseness of solution when dealing with large data sets, the ability to handle large feature spaces, and the ability to identify outliers. They test several SVMs that use different similarity metrics, as well as some other supervised learning methods, and find that the SVMs best identify sets of genes with a common function using expression data. Finally, they use SVMs to predict functional roles for uncharacterized yeast ORFs based on their expression data.

William Grundy; Manuel Ares, Jr.; David Haussler

2001-06-18T23:59:59.000Z

367

Quantifying extrinsic noise in gene expression using the maximum entropy framework  

E-Print Network [OSTI]

We present a maximum entropy framework to separate intrinsic and extrinsic contributions to noisy gene expression solely from the profile of expression. We express the experimentally accessible probability distribution of the copy number of the gene product (mRNA or protein) by accounting for possible variations in extrinsic factors. The distribution of extrinsic factors is estimated using the maximum entropy principle. Our results show that extrinsic factors qualitatively and quantitatively affect the probability distribution of the gene product. We work out, in detail, the transcription of mRNA from a constitutively expressed promoter in {\\it E. coli}. We suggest that the variation in extrinsic factors may account for the observed {\\it wider than Poisson} distribution of mRNA copy numbers. We successfully test our framework on a numerical simulation of a simple gene expression scheme that accounts for the variation in extrinsic factors. We also make falsifiable predictions, some of which are tested on previous experiments in {\\it E. coli} while others need verification. Application of the current framework to more complex situations is also discussed.

Purushottam D. Dixit

2013-04-04T23:59:59.000Z

368

Linking Advanced Visualization and MATLAB for the Analysis of 3D Gene Expression Data  

SciTech Connect (OSTI)

Three-dimensional gene expression PointCloud data generated by the Berkeley Drosophila Transcription Network Project (BDTNP) provides quantitative information about the spatial and temporal expression of genes in early Drosophila embryos at cellular resolution. The BDTNP team visualizes and analyzes Point-Cloud data using the software application PointCloudXplore (PCX). To maximize the impact of novel, complex data sets, such as PointClouds, the data needs to be accessible to biologists and comprehensible to developers of analysis functions. We address this challenge by linking PCX and Matlab via a dedicated interface, thereby providing biologists seamless access to advanced data analysis functions and giving bioinformatics researchers the opportunity to integrate their analysis directly into the visualization application. To demonstrate the usefulness of this approach, we computationally model parts of the expression pattern of the gene even skipped using a genetic algorithm implemented in Matlab and integrated into PCX via our Matlab interface.

Ruebel, Oliver; Keranen, Soile V.E.; Biggin, Mark; Knowles, David W.; Weber, Gunther H.; Hagen, Hans; Hamann, Bernd; Bethel, E. Wes

2011-03-30T23:59:59.000Z

369

Cloning and expression of autogenes encoding RNA polymerases of T7-like bacteriophages  

DOE Patents [OSTI]

This invention relates to the cloning and expression of autogenes encoding RNA polymerases of T7 and T7-like bacteriophages, in which the RNA polymerase gene is transcribed from a promoter which is recognized by the encoded RNA polymerase. Cloning of T7 autogenes was achieved by reducing the activity of the RNA polymerase sufficiently to permit host cell growth. T7 RNA polymerase activity was controlled by combining two independent methods: lac-repression of the recombinant lac operator-T7 promoter in the autogene and inhibition of the polymerase by T7 lysozyme. Expression systems for producing the RNA polymerases of T7 and other T7-like bacteriophages, and expression systems for producing selected gene products are described, as well as other related materials and methods. 12 figs.

Studier, F.W.; Dubendorff, J.W.

1998-11-03T23:59:59.000Z

370

Cloning and expression of autogenes encoding RNA polymerases of T7-like bacteriophages  

DOE Patents [OSTI]

This invention relates to the cloning and expression of autogenes encoding RNA polymerases of T7 and T7-like bacteriophages, in which the RNA polymerase gene is transcribed from a promoter which is recognized by the encoded RNA polymerase. Cloning of T7 autogenes was achieved by reducing the activity of the RNA polymerase sufficiently to permit host cell growth. T7 RNA polymerase activity was controlled by combining two independent methods: lac-repression of the recombinant lac operator-T7 promoter in the autogene and inhibition of the polymerase by T7 lysozyme. Expression systems for producing the RNA polymerases of T7 and other T7-like bacteriophages, and expression systems for producing selected gene products are described, as well as other related materials and methods. 12 figs.

Studier, F.W.; Dubendorff, J.W.

1998-10-20T23:59:59.000Z

371

Protocol for Uniformly Measuring and Expressing the Performance of Energy Storage Systems  

SciTech Connect (OSTI)

The Protocol for Uniformly Measuring and Expressing the Performance of Energy Storage Systems (PNNL-22010) was first issued in November 2012 as a first step toward providing a foundational basis for developing an initial standard for the uniform measurement and expression of energy storage system (ESS) performance. Its subsequent use in the field and review by the protocol working group and most importantly the users’ subgroup and the thermal subgroup has led to the fundamental modifications reflected in this update of the 2012 Protocol. As an update of the 2012 Protocol, this document (the June 2014 Protocol) is intended to supersede its predecessor and be used as the basis for measuring and expressing ESS performance. The foreword provides general and specific details about what additions, revisions, and enhancements have been made to the 2012 Protocol and the rationale for them in arriving at the June 2014 Protocol.

Conover, David R.; Crawford, Aladsair J.; Viswanathan, Vilayanur V.; Ferreira, Summer; Schoenwald, David

2014-06-01T23:59:59.000Z

372

Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation  

SciTech Connect (OSTI)

The bcl-2 and c-myc proto-oncogenes are brought into juxtaposition with the immuno-globulin heavy chain locus in particular B-cell lymphomas, resulting in high levels of constitutive accumulation of their messenger RNAs. Precisely how the products of the bcl-2 and c-myc genes contribute to tumorigenesis is unknown, but observations that c-myc expression is rapidly induced in nonneoplastic lymphocytes upon stimulation of proliferation raise the possibility that this proto-oncogene is involved in the control of normal cellular growth. In addition to c-myc, the bcl-2 proto-oncogene also was expressed in normal human B and T lymphocytes after stimulation with appropriate mitogens. Comparison of the regulation of the expression of these proto-oncogenes demonstrated marked differences and provided evidence that, in contrast to c-myc, levels of bcl-2 messenger RNA are regulated primarily though transcriptional mechanisms. 10 references, 3 figures.

Reed, J.C.; Tsujimoto, Y.; Alpers, J.D.; Croce, C.M.; Nowell, P.C.

1987-06-05T23:59:59.000Z

373

Femtosecond spectroscopy probes the folding quality of antibody fragments expressed as GFP fusions in the cytoplasm  

SciTech Connect (OSTI)

Time-resolved femtosecond spectroscopy can improve the application of green fluorescent proteins (GFPs) as protein-folding reporters. The study of ultrafast excited-state dynamics (ESD) of GFP fused to single chain variable fragment (scFv) antibody fragments, allowed us to define and measure an empirical parameter that only depends on the folding quality (FQ) of the fusion. This method has been applied to the analysis of genetic fusions expressed in the bacterial cytoplasm and allowed us to distinguish folded and thus functional antibody fragments (high FQ) with respect to misfolded antibody fragments. Moreover, these findings were strongly correlated to the behavior of the same scFvs expressed in animal cells. This method is based on the sensitivity of the ESD to the modifications in the tertiary structure of the GFP induced by the aggregation state of the fusion partner. This approach may be applicable to the study of the FQ of polypeptides over-expressed under reducing conditions.

Didier, P. [Faculte de Pharmacie, UMR 7175, 74, route du Rhin, 67412 Illkirch (France); Weiss, E.; Sibler, A.-P. [Ecole Superieure de Biotechnologie de Strasbourg, UMR 7175, Boulevard Sebastien Brant, F-67412 Illkirch (France); Philibert, P.; Martineau, P. [Centre de recherche en cancerologie de Montpellier, UMR 5160, Val d'Aurelle-Paul Lamarque, 34298 Montpellier cedex 5 (France); Bigot, J.-Y. [Institut de Physique et Chimie des Materiaux de Strasbourg, UMR 7504, 23, rue du Loess, F-67037 Strasbourg (France); Guidoni, L. [Institut de Physique et Chimie des Materiaux de Strasbourg, UMR 7504, 23, rue du Loess, F-67037 Strasbourg (France); Laboratoire Materiaux et Phenomenes Quantiques, UMR 7162, Batiment Condorcet, 10 rue Alice Domon et Leonie Duquet, 75205 Paris cedex 13 (France)], E-mail: luca.guidoni@univ-paris-diderot.fr

2008-02-22T23:59:59.000Z

374

PROCEEDINGS OF WORKSHOP ON THERMOMECHANICAL-HYDROCHEMICAL MODELING FOR A HARDROCK WASTE REPOSITORY. JULY 29-31, 1980. MARRIOTT INN, BERKELEY, CA  

E-Print Network [OSTI]

Hanford Operations INTRODUCTION A major expansion of the U.S. Government radioactive waste management

Authors, Various

2010-01-01T23:59:59.000Z

375

PROCEEDINGS OF THE CONFERENCE ON ENERGY RESEARCH AT HISTORICALLY BLACK UNIVERSITIES, JUNE 17-19, 1980, SHERATON PATRIOT INN, WILLIAMSBURG, VIRGINIA  

E-Print Network [OSTI]

jet stream winds. Superior wind power density and relativeNovel Approaches to Wind and Solar Power Generation z. W.NOVEL APPROACHES TO WIND AND SOLAR POWER GENERATION Dr. Z.

Authors, Various

2014-01-01T23:59:59.000Z

376

PROCEEDINGS OF WORKSHOP ON THERMOMECHANICAL-HYDROCHEMICAL MODELING FOR A HARDROCK WASTE REPOSITORY. JULY 29-31, 1980. MARRIOTT INN, BERKELEY, CA  

E-Print Network [OSTI]

Stripa Project, Univ, of Lulea, Sweden. Rarnspott, L, D. --1979 in progress. Univ. Lulea) Buffer Mass Test: PI acement

Authors, Various

2010-01-01T23:59:59.000Z

377

PROCEEDINGS OF WORKSHOP ON THERMOMECHANICAL-HYDROCHEMICAL MODELING FOR A HARDROCK WASTE REPOSITORY. JULY 29-31, 1980. MARRIOTT INN, BERKELEY, CA  

E-Print Network [OSTI]

portions including two joint block test will be brought on-into the block following a single vertical joint and packed

Authors, Various

2010-01-01T23:59:59.000Z

378

PROCEEDINGS OF WORKSHOP ON THERMOMECHANICAL-HYDROCHEMICAL MODELING FOR A HARDROCK WASTE REPOSITORY. JULY 29-31, 1980. MARRIOTT INN, BERKELEY, CA  

E-Print Network [OSTI]

l Lab P. O. Box 808 Livermore, CA 94550 Gary D. Callahan RE/Lab P. O. Box 808 Livermore, CA 94550 Neville L. Carter RE/90A 1 Cyclotron Road Berkeley, CA 94720 Robbin G. Charlwood

Authors, Various

2010-01-01T23:59:59.000Z

379

Bio-Derived Liquids to Hydrogen Distributed Reforming Working Group (BILIWG) Kick-Off Meeting Proceedings Hilton Garden Inn-BWI,Baltimore, MD October 24, 2006  

Broader source: Energy.gov [DOE]

Proceedings from the October 24, 2006 Bio-Derived Liquids to Hydrogen Distributed Reforming Working Group Kick-Off Meeting.

380

PROCEEDINGS OF WORKSHOP ON THERMOMECHANICAL-HYDROCHEMICAL MODELING FOR A HARDROCK WASTE REPOSITORY. JULY 29-31, 1980. MARRIOTT INN, BERKELEY, CA  

E-Print Network [OSTI]

Isolation Project, Rockwell Hanford Opera- tions, RHO-BWI-A&M John B. Case Rockwell Hanford Operations N.G.W. Cook UCBJ. G. Patricio Rockwell Hanford Operations Bob Ri ecker lASl

Authors, Various

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Matrigel Basement Membrane Matrix influences expression of microRNAs in cancer cell lines  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Matrigel alters cancer cell line miRNA expression relative to culture on plastic. Black-Right-Pointing-Pointer Many identified Matrigel-regulated miRNAs are implicated in cancer. Black-Right-Pointing-Pointer miR-1290, -210, -32 and -29b represent a Matrigel-induced miRNA signature. Black-Right-Pointing-Pointer miR-32 down-regulates Integrin alpha 5 (ITGA5) mRNA. -- Abstract: Matrigel is a medium rich in extracellular matrix (ECM) components used for three-dimensional cell culture and is known to alter cellular phenotypes and gene expression. microRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression and have roles in cancer. While miRNA profiles of numerous cell lines cultured on plastic have been reported, the influence of Matrigel-based culture on cancer cell miRNA expression is largely unknown. This study investigated the influence of Matrigel on the expression of miRNAs that might facilitate ECM-associated cancer cell growth. We performed miRNA profiling by microarray using two colon cancer cell lines (SW480 and SW620), identifying significant differential expression of miRNAs between cells cultured in Matrigel and on plastic. Many of these miRNAs have previously been implicated in cancer-related processes. A common Matrigel-induced miRNA signature comprised of up-regulated miR-1290 and miR-210 and down-regulated miR-29b and miR-32 was identified using RT-qPCR across five epithelial cancer cell lines (SW480, SW620, HT-29, A549 and MDA-MB-231). Experimental modulation of these miRNAs altered expression of their known target mRNAs involved in cell adhesion, proliferation and invasion, in colon cancer cell lines. Furthermore, ITGA5 was identified as a novel putative target of miR-32 that may facilitate cancer cell interactions with the ECM. We propose that culture of cancer cell lines in Matrigel more accurately recapitulates miRNA expression and function in cancer than culture on plastic and thus is a valuable approach to the in vitro study of miRNAs.

Price, Karina J. [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia) [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia); School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA 6008 (Australia); Tsykin, Anna [Centre for Cancer Biology, SA Pathology, Adelaide, SA 5000 (Australia) [Centre for Cancer Biology, SA Pathology, Adelaide, SA 5000 (Australia); School of Molecular and Biomedical Science, University of Adelaide, Adelaide, SA 5005 (Australia); Giles, Keith M. [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia)] [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia); Sladic, Rosemary T. [Centre for Cancer Biology, SA Pathology, Adelaide, SA 5000 (Australia)] [Centre for Cancer Biology, SA Pathology, Adelaide, SA 5000 (Australia); Epis, Michael R. [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia)] [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia); Ganss, Ruth [Laboratory for Cancer Medicine Angiogenesis Unit, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia)] [Laboratory for Cancer Medicine Angiogenesis Unit, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia); Goodall, Gregory J. [Centre for Cancer Biology, SA Pathology, Adelaide, SA 5000 (Australia) [Centre for Cancer Biology, SA Pathology, Adelaide, SA 5000 (Australia); School of Molecular and Biomedical Science, University of Adelaide, Adelaide, SA 5005 (Australia); Department of Medicine, University of Adelaide, Adelaide, SA 5005 (Australia); Leedman, Peter J., E-mail: peter.leedman@waimr.uwa.edu.au [Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and University of Western Australia Centre for Medical Research, Perth, WA 6000 (Australia); School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA 6008 (Australia)

2012-10-19T23:59:59.000Z

382

Engineering of living cells for the expression of holo-phycobiliprotein-based constructs  

DOE Patents [OSTI]

Recombinant cells which express a fluorescent holo-phycobiliprotein fusion protein and methods of use are described. The cells comprises a bilin, a recombinant bilin reductase, an apo-phycobiliprotein fusion protein precursor of the fusion protein comprising a corresponding apo-phycobiliprotein domain, and a recombinant phycobiliprotein domain-bilin lyase, which components react to form the holo-phycobiliprotein fusion protein. Also described are holo-phycobiliprotein based transcription reporter cells and assays, which cells conditionally express a heterologous-to-the-cell, fluorescent, first holo-phycobiliprotein domain.

Glazer, Alexander N.; Tooley, Aaron J.; Cai, Yuping

2004-05-25T23:59:59.000Z

383

Expression patterns of FLAGELLIN SENSING 2 map to bacterial entry sites in plant shoots and roots  

E-Print Network [OSTI]

to a defined trade-off between immune and hormonal signal- ling (Gomez-Gomez et al., 1999; Navarro et al., 2006, 2008; Lozano-Duran et al., 2013). Publicly available gene expression data (Arabidopsis eFP browser; Faulkner and Robatzek, 2012) revealed... ; Navarro et al., 2006). The findings are also con- sistent with reduced DR5–GUS expression in roots and inhibition of auxin-mediated adventitious root growth when triggered with oligogalacturonides, components of the plant cell wall known to trigger...

Beck, Martina; Wyrsch, Ines; Strutt, James; Wimalasekera, Rinukshi; Webb, Alex; Boller, Thomas; Robatzek, Silke

2014-09-09T23:59:59.000Z

384

Sustainable Energy Concepts: A Sustainable energy concept for Safari Resort Beekse Bergen:.  

E-Print Network [OSTI]

??Research to sustainable energy concepts with a holiday resort as case study. Near the safaripark a new holiday resort will be built. The missing natrual… (more)

Vons, G.J.

2011-01-01T23:59:59.000Z

385

Empirical Study of the Healing Nature of Artistic Expression: Using Mandalas with the Positive Emotions of Love and Joy  

E-Print Network [OSTI]

EMPIRICAL STUDY OF THE HEALING NATURE OF ARTISTIC EXPRESSION: USING MANDALAS WITH THE POSITIVE EMOTIONS OF LOVE AND JOY A Dissertation by PATTI GAIL HENDERSON Submitted to the Office of Graduate Studies of Texas... Empirical Study of the Healing Nature of Artistic Expression: Using Mandalas with the Positive Emotions of Love and Joy Copyright 2012 Patti Gail Henderson EMPIRICAL STUDY OF THE HEALING NATURE OF ARTISTIC EXPRESSION: USING MANDALAS...

Henderson, Patti Gail

2012-07-16T23:59:59.000Z

386

Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons  

E-Print Network [OSTI]

Recombinant rabies viruses rendered replication-deficient by the deletion of their envelope glycoprotein gene are useful tools for neuroscientists, permitting (1) extraordinarily high transgene expression levels within ...

Wickersham, Ian R.

387

Expression of Multiple Artificial MicroRNAs from a Chicken miRNA126-Based Lentiviral Vector  

E-Print Network [OSTI]

Background: The use of RNAi in both basic and translational research often requires expression of multiple siRNAs from the

Chen, Steve C.-Y.

388

Expressive Visual Speech using Geometric Muscle Functions James D. Edge and Steve Maddock  

E-Print Network [OSTI]

, Expression 1 Introduction It has been found in the field of Computer Facial Animation that the closer models human faces. The problems of facial animation are increased when we consider Visual Speech speech synchronous animation is also demonstrated. It is considered that models which use a combined

Maddock, Steve

389

Differential Protein Expression in the Insular Cortex and the Amygdala after Taste Memory Acquisition and Retrieval  

E-Print Network [OSTI]

later. An increase in ARC expression 30 minutes after reactivation of the aversive taste was seen in the basolateral amygdala and the CeA exhibited a similar increase at 60 and 90 minutes. Local infusion of ARC antisense oligonucleotides within the IC...

Venkataraman, Archana

2013-05-03T23:59:59.000Z

390

Computer-aided evaluation of protein expression in pathological tissue images Elisa Ficarra, Enrico Macii  

E-Print Network [OSTI]

by pathologists via visual inspection of tissue sam- ples images. Our techniques streamlines this errorComputer-aided evaluation of protein expression in pathological tissue images Elisa Ficarra, Enrico in pathological tissues by using, for example, images of the tissue where the localization of pro- teins, as well

De Micheli, Giovanni

391

Projecting 2D Gene Expression Data Into 3D and 4D Space  

E-Print Network [OSTI]

imaging of wholemount stained sam- ples. The two-dimensional images thus generated are, in fact games typically generate virtual 3D objects by texture mapping an image onto a 3D polygonal frame mapping images of gene expression data onto b-spline based embryo models. This approach, known as UV

Vize, Peter D.

392

Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate  

SciTech Connect (OSTI)

Pretreatment of mice with the peroxisome proliferator clofibrate (CFB) protects against acetaminophen (APAP)-induced hepatotoxicity. Previous studies have shown that activation of the nuclear peroxisome proliferator activated receptor-alpha (PPAR{alpha}) is required for this effect. The present study utilizes gene expression profile analysis to identify potential pathways contributing to PPAR{alpha}-mediated hepatoprotection. Gene expression profiles were compared between wild type and PPAR{alpha}-null mice pretreated with vehicle or CFB (500 mg/kg, i.p., daily for 10 days) and then challenged with APAP (400 mg/kg, p.o.). Total hepatic RNA was isolated 4 h after APAP treatment and hybridized to Affymetrix Mouse Genome MGU74 v2.0 GeneChips. Gene expression analysis was performed utilizing GeneSpring (registered) software. Our analysis identified 53 genes of interest including vanin-1, cell cycle regulators, lipid-metabolizing enzymes, and aldehyde dehydrogenase 2, an acetaminophen binding protein. Vanin-1 could be important for CFB-mediated hepatoprotection because this protein is involved in the synthesis of cysteamine and cystamine. These are potent antioxidants capable of ameliorating APAP toxicity in rodents and humans. HPLC-ESI/MS/MS analysis of liver extracts indicates that enhanced vanin-1 gene expression results in elevated cystamine levels, which could be mechanistically associated with CFB-mediated hepatoprotection.

Moffit, Jeffrey S. [University of Connecticut, Department of Pharmaceutical Sciences, Storrs, CT (United States); Koza-Taylor, Petra H. [Pfizer, Inc., Groton Laboratories, Molecular and Investigative Toxicology, Groton, CT (United States); Holland, Ricky D. [National Center for Toxicological Research, Division of Systems Toxicology, Jefferson, AR (United States); Thibodeau, Michael S. [University of Connecticut, Department of Pharmaceutical Sciences, Storrs, CT (United States); Beger, Richard D. [National Center for Toxicological Research, Division of Systems Toxicology, Jefferson, AR (United States); Lawton, Michael P. [Pfizer, Inc., Groton Laboratories, Molecular and Investigative Toxicology, Groton, CT (United States); Manautou, Jose E. [University of Connecticut, Department of Pharmaceutical Sciences, Storrs, CT (United States)]. E-mail: jose.manautou@uconn.edu

2007-07-15T23:59:59.000Z

393

Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase  

SciTech Connect (OSTI)

FAD synthetase (FADS) (EC 2.7.7.2) is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor FAD. Two hypothetical human FADSs, which are the products of FLAD1 gene, were over-expressed in Escherichia coli and identified by ESI-MS/MS. Isoform 1 was over-expressed as a T7-tagged protein which had a molecular mass of 63 kDa on SDS-PAGE. Isoform 2 was over-expressed as a 6-His-tagged fusion protein, carrying an extra 84 amino acids at the N-terminal with an apparent molecular mass of 60 kDa on SDS-PAGE. It was purified near to homogeneity from the soluble cell fraction by one-step affinity chromatography. Both isoforms possessed FADS activity and had a strict requirement for MgCl{sub 2}, as demonstrated using both spectrophotometric and chromatographic methods. The purified recombinant isoform 2 showed a specific activity of 6.8 {+-} 1.3 nmol of FAD synthesized/min/mg protein and exhibited a K {sub M} value for FMN of 1.5 {+-} 0.3 {mu}M. This is First report on characterization of human FADS, and First cloning and over-expression of FADS from an organism higher than yeast.

Brizio, Carmen [Dipartimento di Biochimica e Biologia Molecolare 'Ernesto Quagliariello', Universita degli Studi di Bari, Via Orabona 4, I-70126 Bari (Italy); Galluccio, Michele [Dipartimento di Biologia Cellulare, Universita della Calabria, Via P. Bucci 4c, I-87036 Arcavacata di Rende (Italy); Wait, Robin [Kennedy Institute of Rheumatology Division, Faculty of Medicine, Imperial College London, 1 Aspenlea Road, Hammersmith, London W6 8LH (United Kingdom); Torchetti, Enza Maria [Dipartimento di Biochimica e Biologia Molecolare 'Ernesto Quagliariello', Universita degli Studi di Bari, Via Orabona 4, I-70126 Bari (Italy); Bafunno, Valeria [Dipartimento di Biochimica e Biologia Molecolare 'Ernesto Quagliariello', Universita degli Studi di Bari, Via Orabona 4, I-70126 Bari (Italy); Accardi, Rosita [Infections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372 Lyon (France); Gianazza, Elisabetta [Gruppo di Studio per la Proteomica e la Struttura delle Proteine, Dipartimento di Scienze Farmacologiche, Universita degli Studi di Milano, Via G. Balzaretti 9, I-20133 Milan (Italy); Indiveri, Cesare [Dipartimento di Biologia Cellulare, Universita della Calabria, Via P. Bucci 4c, I-87036 Arcavacata di Rende (Italy); Barile, Maria [Dipartimento di Biochimica e Biologia Molecolare 'Ernesto Quagliariello', Universita degli Studi di Bari, Via Orabona 4, I-70126 Bari (Italy) and Istituto di Biomembrane e Bioenergetica, C.N.R., Via Amendola 165/A, I-70126 Bari (Italy)]. E-mail: m.barile@biologia.uniba.it

2006-06-09T23:59:59.000Z

394

Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease  

E-Print Network [OSTI]

, and therein is regulated by injury. In the case of CNS demyelinating disease, K6 expression in CNS occurs in a tissue- specific fashion and are differentially regulated in response to CNS injury. While the human peripheral tissue. In a murine model of human CNS demyelinating inflammatory disease induced by Theiler's pi

Blaber, Michael

395

Expressive Statistical Model Checking of Genetic Networks with Delayed Stochastic Dynamics  

E-Print Network [OSTI]

introduced Hybrid Automata Stochastic Logic (HASL) [8] establishes a powerful framework for the analysis demonstrate the potential of HASL based verification in the context of genetic circuits. To this aim we properties related to this model, formally express them in HASL terms and, assess them with COSMOS

Paris-Sud XI, Université de

396

Mosaic Analysis of GL2 Gene Expression and Cell Layer Autonomy During the Specification of  

E-Print Network [OSTI]

ARTICLE Mosaic Analysis of GL2 Gene Expression and Cell Layer Autonomy During the Specification: Homozygous glabra2 (gl2) mutant Arabidop- sis thaliana Landsberg erecta plants with only a few rudimentary single spiked trichomes on the leaf margin were transformed with a genomic clone of GL2, resulting

Murray, J.A.H.

397

Determinantal expressions for Macdonald polynomials L. Lapointe, A. Lascoux, and J. Morse  

E-Print Network [OSTI]

Determinantal expressions for Macdonald polynomials L. Lapointe, A. Lascoux, and J. Morse Institut in -rings. This provides explicit formulas for the Macdonald polynomials expanded in this basis as well of symmetric functions rely on the use of the Macdonald polynomial basis, {J(X; q, t)} [M1]. This basis

Morse, Jennifer

398

Determinantal expressions for Macdonald polynomials L. Lapointe, A. Lascoux, and J. Morse  

E-Print Network [OSTI]

Determinantal expressions for Macdonald polynomials L. Lapointe, A be reduced to addition in ~-rings. This provides explicit formulas for the * *Macdonald polynomials of the Macdonald polynomial basis, {J~(X; q, t)}~ [M1]. This basis specializes to seve* *ral fundamen- tal bases

Lascoux, Alain

399

Determinantal expressions for Macdonald polynomials L. Lapointe, A. Lascoux, and J. Morse  

E-Print Network [OSTI]

Determinantal expressions for Macdonald polynomials L. Lapointe, A. Lascoux, and J. Morse Institut to addition in #21; rings. This provides explicit formulas for the Macdonald polynomials expanded]. Introduction Important developments in the theory of symmetric functions rely on the use of the Macdonald

Lascoux, Alain

400

A Multimodal Fuzzy Inference System Using a Continuous Facial Expression Representation for Emotion Detection  

E-Print Network [OSTI]

Pro- cessing and Computer Vision]: Image Representation; I.5.1 [Pattern Recognition]: ModelsA Multimodal Fuzzy Inference System Using a Continuous Facial Expression Representation for Emotion a multimodal fuzzy inference system for emotion detection. The system extracts and merges visual, acoustic

Pelachaud, Catherine

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

PERFECT POWERS EXPRESSIBLE AS SUMS OF TWO CUBES IMIN CHEN AND SAMIR SIKSEK  

E-Print Network [OSTI]

PERFECT POWERS EXPRESSIBLE AS SUMS OF TWO CUBES IMIN CHEN AND SAMIR SIKSEK To John Cannon and Derek a combination of the modular approach (via Frey curves and Galois representations) with obstructions 11D41, Secondary 11G30. Key words and phrases. Diophantine equations, Frey curves, level

Siksek, Samir

402

Heart valve cardiomyocytes of mouse embryos express the serotonin transporter SERT  

SciTech Connect (OSTI)

Multiple evidence demonstrate a role for serotonin and its transporter SERT in heart valve development and disease. By utilizing a Cre/loxP system driven by SERT gene expression, we recently demonstrated a regionally restricted distribution of SERT-expressing cells in developing mouse heart. In order to characterize the cell types exhibiting SERT expression within the mouse heart valves at early developmental stages, in this study we performed immunohistochemistry for Islet1 (Isl1) and connexin-43 (Cx-43) on heart sections from SERT{sup Cre/+};ROSA26R embryos previously stained with X-gal. We observed the co-localization of LacZ staining with Isl1 labelling in the outflow tract, the right ventricle and the conal region of E11.5 mouse heart. Cx-43 labelled cells co-localized with LacZ stained cells in the forming atrioventricular valves. These results demonstrate the cardiomyocyte phenotype of SERT-expressing cells in heart valves of the developing mouse heart, thus suggesting an active role of SERT in early heart valve development.

Pavone, Luigi Michele [Department of Biological Structures, Functions and Technologies, University of Naples Federico II, Via F. Delpino 1, 80137 Naples (Italy); Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Naples (Italy)], E-mail: pavone@dbbm.unina.it; Spina, Anna; Lo Muto, Roberta; Santoro, Dionea [Department of Biological Structures, Functions and Technologies, University of Naples Federico II, Via F. Delpino 1, 80137 Naples (Italy); Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Naples (Italy); Mastellone, Vincenzo [Department of Experimental Medicine 'G. Salvatore', University of Magna Graecia, Catanzaro (Italy); Avallone, Luigi [Department of Biological Structures, Functions and Technologies, University of Naples Federico II, Via F. Delpino 1, 80137 Naples (Italy)

2008-12-12T23:59:59.000Z

403

Effects of Sampling Context on Spontaneous Expressive Language in Males With Fragile  

E-Print Network [OSTI]

X Syndrome or Down Syndrome Sara T. Kover,a Andrea McDuffie,b Leonard Abbeduto,b and W. Ted Brownc of expressive language in male participants with fragile X syndrome in comparison to male participants with Down, were matched groupwise on nonverbal mental age to adolescents with Down syndrome (n = 15) and typically

Nguyen, Danh

404

A New Expression for 3N Bound State Faddeev Equation in a 3D Approach  

E-Print Network [OSTI]

A spin-isospin dependent three-dimensional approach has been applied for formulation of the three-nucleon bound state and a new expression for Faddeev equation based on three-nucleon free basis state has been obtained. Then the three-nucleon wave function has been obtained as a function of five independent variables.

M. Harzchi; S. Bayegan

2011-06-27T23:59:59.000Z

405

Altered Stra13 and Dec2 circadian gene expression in hypoxic cells  

SciTech Connect (OSTI)

The circadian system regulates rhythmically most of the mammalian physiology in synchrony with the environmental light/dark cycle. Alteration of circadian clock gene expression has been associated with tumour progression but the molecular links between the two mechanisms remain poorly defined. Here we show that Stra13 and Dec2, two circadian transcriptional regulators which play a crucial role in cell proliferation and apoptosis are overexpressed and no longer rhythmic in serum shocked fibroblasts treated with CoCl{sub 2,} a substitute of hypoxia. This effect is associated with a loss of circadian expression of the clock genes Rev-erb{alpha} and Bmal1, and the clock-controlled gene Dbp. Consistently, cotransfection assays demonstrate that STRA13 and DEC2 both antagonize CLOCK:BMAL1 dependent transactivation of the Rev-erb{alpha} and Dbp promoters. Using a transplantable osteosarcoma tumour model, we show that hypoxia is associated with altered circadian expression of Stra13, Dec2, Rev-erb{alpha}, Bmal1 and Dbp in vivo. These observations collectively support the notion that overexpression of Stra13 and Dec2 links hypoxia signalling to altered circadian clock gene expression.

Guillaumond, Fabienne; Lacoche, Samuel; Dulong, Sandrine; Grechez-Cassiau, Aline [Universite de Nice-Sophia Antipolis, CNRS FRE3094, 28 Av. Valrose, 06108 Nice (France); Filipski, Elisabeth; Li, Xiao-Mei; Levi, Francis [Universite Paris-Sud, INSERM U776, Hopital Paul Brousse, 14 Av. P.V. Couturier, 94800 Villejuif (France); Berra, Edurne [Cell Biology and Stem Cells Unit, CIC BioGUNE, Technologic Park of Bizkaia, 48160-Derio (Spain); Delaunay, Franck [Universite de Nice-Sophia Antipolis, CNRS FRE3094, 28 Av. Valrose, 06108 Nice (France); Teboul, Michele [Universite de Nice-Sophia Antipolis, CNRS FRE3094, 28 Av. Valrose, 06108 Nice (France)], E-mail: teboulm@unice.fr

2008-05-16T23:59:59.000Z

406

Master BBSG 1 anne TP Programmation & langage Python TP 6. Expressions rgulires  

E-Print Network [OSTI]

adresses dans le web) contenues dans une page web. Ces URL apparaissent dans des liens, réalisés par des'expression régulière qui capture une telle balise (module re, fonction compile(), méthode search()). Par exemple si

Tichit, Laurent

407

CORRELATED EVOLUTION OF FRUIT SIZE AND SEXUAL EXPRESSION IN ANDROMONOECIOUS SOLANUM SECTIONS  

E-Print Network [OSTI]

CORRELATED EVOLUTION OF FRUIT SIZE AND SEXUAL EXPRESSION IN ANDROMONOECIOUS SOLANUM SECTIONS production is a mechanism to regulate allocation to female function (i.e., fruit production), then large-fruited species should be more strongly andromonoecious than smaller-fruited taxa because more resources

Miller, Jill S.

408

Cellulase variants with improved expression, activity and stability, and use thereof  

DOE Patents [OSTI]

The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.

Aehle, Wolfgang; Bott, Richard R; Bower, Benjamin; Caspi, Jonathan; Estell, David A; Goedegebuur, Frits; Hommes, Ronaldus W.J.; Kaper, Thijs; Kelemen, Bradley; Kralj, Slavko; Van Lieshout, Johan; Nikolaev, Igor; Van Stigt Thans, Sander; Wallace, Louise; Vogtentanz, Gudrun; Sandgren, Mats

2014-03-25T23:59:59.000Z

409

OETS SPEAK of attaining some distance from the world --finding some strangeness --to express the  

E-Print Network [OSTI]

the truths that make a rock stony or a love sublime. Like the poet, the physicist seeks not merely to name sublime. Like the poet, the physicist seeks not merely to name the properties of nature, but to plumb strangeness -- to express the truths that make a rock stony or a love sublime. Like the poet, the physicist

Quigg, Chris

410

Tracking of Transgene Expression in Soybean using Robotics and GFP John James Finer  

E-Print Network [OSTI]

Tracking of Transgene Expression in Soybean using Robotics and GFP John James Finer Department system that is composed of a 2-dimensional robotics platform, a Leica MZFLIII fluorescence dissecting on the robotics platform. The platform contains docking centers for 16 Petri dishes, which are secured

Finer, John J.

411

A Microfluidic Device for Temporally Controlled Gene Expression and Long-Term Fluorescent Imaging in  

E-Print Network [OSTI]

A Microfluidic Device for Temporally Controlled Gene Expression and Long-Term Fluorescent Imaging of the cell cycle. Over the past ten years, microfluidic techniques in cell biology have emerged that allow a microfluidic flow cell to grow Saccharomyces Cerevisiae for more than 8 generations (

Siggia, Eric

412

MOLECULAR CLONING, BACULOVIRUS EXPRESSION, AND TISSUE DISTRIBUTION OF THE ZEBRAFISH ALDEHYDE DEHYDROGENASE 2  

E-Print Network [OSTI]

ABSTRACT: Ethanol is metabolized to acetaldehyde mainly by the alcohol de- hydrogenase pathway and is responsible for some of the deleterious effects of ethanol, is further oxidized to acetic acid by aldehyde zebrafish (Danio rerio) as a model for ethanol metabolism by cloning, expressing, and characterizing

Tullos, Desiree

413

3D Facial Landmark Detection under Large Yaw and Expression Variations  

E-Print Network [OSTI]

3D Facial Landmark Detection under Large Yaw and Expression Variations Panagiotis Perakis, Member on 3D facial scans under large yaw variations (that often result in missing facial data), and its registration, based on the landmark points' correspondence, is necessary in order to make a system fully

Kakadiaris, Ioannis

414

Expressive Footwear for Computer-Augmented Dance Performance Joseph A. Paradiso and Eric Hu  

E-Print Network [OSTI]

]; the signals are several volts into a high-impedance ( 10 MegOhm) load, thus require only simple buffering system is described for instrumenting a pair of dancing shoes in order to capture many expressive degrees pressure is measured at three points in the shoe sole, as are the bend of the sole, pitch and yaw shoe

415

Call for expression of interest EU-Brazil Technology and Innovation Forum  

E-Print Network [OSTI]

for Brazilian SMEs, Technological Parks and other innovation actors for cooperation with Europe (Tour of BrazilCall for expression of interest EU-Brazil Technology and Innovation Forum Participation to B2B targeting research and innovation actors. Among them, this year the EU-Brazil Technology and Innovation

416

A closed-form approximate expression for the optical conductivity of graphene  

E-Print Network [OSTI]

A closed-form approximate expression for the optical conductivity of graphene Ergun Simsek School for the optical conductivity of graphene is developed, which generates re- sults with less than 0.8% maximum.001437 Graphene, a one atom thick sheet of carbon atoms, has been receiving a great deal of interest since its

Simsek, Ergun

417

Product development with a focus on attractive product expression: an analysis of case studies  

E-Print Network [OSTI]

1 Product development with a focus on attractive product expression: an analysis of case studies products is vital for a company's endurance in competitive markets. A mix of functionality, ergonomics, aesthetics, symbols and price aspects all play a role in making a product desirable. Some products carry

Paris-Sud XI, Université de

418

Aluminum Tolerance in Alfalfa as Expressed in Tissue Culture w. A. Parrot and J. H. Bouton*  

E-Print Network [OSTI]

Aluminum Tolerance in Alfalfa as Expressed in Tissue Culture w. A. Parrot and J. H. Bouton worldandgreatlylimitgrowthof Al-sensitive cropslike alfalfa, MedicagosativaL. Alfalfagermplasmswerese- lectedto impediment to the growth of alfalfa in manyareas of the world. This is especially true if the soil contains

Parrott, Wayne

419

A Novel Approach to Determine Normal Variation in Gene Expression Data  

E-Print Network [OSTI]

and regulation. In the last decade the development of mouse models for cancer, dia- betes, neuro to experimental noise in each of the mice and then mines for normal variance among the identical mice-throughput gene expression has become an important tool to study transcriptional activity in a variety of bio

Zaki, Mohammed Javeed

420

Odorant Receptor Expression Defines Functional Units in the Mouse Olfactory System  

E-Print Network [OSTI]

) and influ- ence the guidance of OSN axons to synaptic targets in the olfactory bulb (OB). OSNs expressing of single neurons from gene- targeted mice in which the green fluorescent protein is coex- pressed and arrangement of glomerular functional units. Key words: olfaction; olfactory system; olfactory bulb; glo

Bozza, Thomas

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Effects of exercise or oocyte heat shock on embryo development and gene expression in the horse  

E-Print Network [OSTI]

experiments were examined for HSP70 gene expression by real time RT-PCR. Exercised mares ovulated significantly smaller follicles, 39.8 vs. 41.5 mm diameter, and ovulated later after being given PGF2?, 8.5 vs. 9.2 d. Twenty-two embryos (22/35) were recovered...

Mortensen, Christopher John

2009-05-15T23:59:59.000Z

422

Tyrosinase-Related Protein 2 Promoter Targets Transgene Expression to Ocular and Neural  

E-Print Network [OSTI]

Tyrosinase-Related Protein 2 Promoter Targets Transgene Expression to Ocular and Neural Crest generated transgenic mice carrying the lacZ reporter gene linked to the tyrosinase-related protein 2 (TRP2 mutation. INTRODUCTION Tyrosinase-related protein 2 (TRP2) is an enzyme in- volved in an intermediate step

Cummings, Molly E.

423

Investigating hypoxic tumor physiology through gene expression patterns Nicholas C Denko*,1  

E-Print Network [OSTI]

, these physiologically driven hypoxic gene expression changes give us insight as to the poor outcome of patients energy production. Organisms that rely upon oxygen-dependent energy production suffer when oxygen falls of molecular mechanisms to regulate the cellular availability and usage of oxygen. The response to low

Raychaudhuri, Soumya

424

EIS-0447: Champlain Hudson Power Express Transmission Line Project, New York  

Broader source: Energy.gov [DOE]

This EIS evaluated the potential environmental impacts of a DOE proposal to grant a Presidential permit to Champlain Hudson Power Express, Inc., to construct, operate, maintain, and connect a new 1000-megawatt (MW) electric transmission system across the U.S.-Canada border in northeastern New York State. The proposed transmission line would run from the Canadian Province of Quebec to New York City.

425

GENETIC TRANSFORMATION AND HYBRIDIZATION Bacterial citrate synthase expression and soil aluminum tolerance  

E-Print Network [OSTI]

GENETIC TRANSFORMATION AND HYBRIDIZATION Bacterial citrate synthase expression and soil aluminum that were more aluminum-tolerant than the non-transgenic control, confirming that citrate synthase overexpression can be a useful tool to help achieve aluminum tolerance. Keywords Acid soils Á Aluminum toxicity Á

Parrott, Wayne

426

Victoria Arango, PhD NEURONAL TRYPTOPHAN HYDROXYLASE mRNA EXPRESSION IN THE HUMAN  

E-Print Network [OSTI]

-submitted to Neuropsychopharmacology, August 4, 2005 Running Title: TPH2 mRNA in depressed suicides #12;Victoria Arango, PhD 2 ABSTRACTVictoria Arango, PhD 1 NEURONAL TRYPTOPHAN HYDROXYLASE mRNA EXPRESSION IN THE HUMAN DORSAL. John Mann, MD 1,2 Victoria Arango, PhD 1,2 1 Department of Neuroscience, New York State Psychiatric

Sibille, Etienne

427

The General Education Program Request for Expression of Interest: Scholarship in Practice  

E-Print Network [OSTI]

1 The General Education Program Request for Expression of Interest: Scholarship in Practice Donna B. Hamilton, Dean for Undergraduate Studies August 23, 2010 The General Education Program passed by the Senate as for non-majors. Bearing in mind that implementation of the new General Education program is set for new

Milchberg, Howard

428

Genetic Background Modulates Gene Expression Profile Induced by Skin Irradiation in Ptch1 Mice  

SciTech Connect (OSTI)

Purpose: Ptch1 germ-line mutations in mice predispose to radiation-induced basal cell carcinoma of the skin, with tumor incidence modulated by the genetic background. Here, we examined the possible mechanisms underlying skin response to radiation in F1 progeny of Ptch1{sup neo67/+} mice crossed with either skin tumor-susceptible (Car-S) or -resistant (Car-R) mice and X-irradiated (3 Gy) at 2 days of age or left untreated. Methods and Materials: We conducted a gene expression profile analysis in mRNA samples extracted from the skin of irradiated or control mice, using Affymetrix whole mouse genome expression array. Confirmation of the results was done using real-time reverse-transcriptase polymerase chain reaction. Results: Analysis of the gene expression profile of normal skin of F1 mice at 4 weeks of age revealed a similar basal profile in the nonirradiated mice, but alterations in levels of 71 transcripts in irradiated Ptch1{sup neo67/+} mice of the Car-R cross and modulation of only eight genes in irradiated Ptch1{sup neo67/+} mice of the Car-S cross. Conclusions: These results indicate that neonatal irradiation causes a persistent change in the gene expression profile of the skin. The tendency of mice genetically resistant to skin tumorigenesis to show a more complex pattern of transcriptional response to radiation than do genetically susceptible mice suggests a role for this response in genetic resistance to basal cell tumorigenesis.

Galvan, Antonella; Noci, Sara [Department of Experimental Oncology and Laboratories, Fondazione IRCCS Istituto Nazionale Tumori, Milan (Italy); Mancuso, Mariateresa; Pazzaglia, Simonetta; Saran, Anna [ENEA Laboratories, Rome (Italy); Dragani, Tommaso A. [Department of Experimental Oncology and Laboratories, Fondazione IRCCS Istituto Nazionale Tumori, Milan (Italy)], E-mail: tommaso.dragani@istitutotumori.mi.it

2008-12-01T23:59:59.000Z

429

NANO EXPRESS Open Access Au/Pd core-shell nanoparticles with varied hollow  

E-Print Network [OSTI]

NANO EXPRESS Open Access Au/Pd core-shell nanoparticles with varied hollow Au cores for enhanced on hollow Au nanospheres. The unique nanoparticles were characterized by X-ray diffraction, X of the polycrystalline hollow Au nanospheres was reduced, and the structures became highly porous. After the Pd shell

Liu, Fuqiang

430

Systems for the expression of orthogonal translation components in eubacterial host cells  

DOE Patents [OSTI]

The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.

Ryu, Youngha (San Diego, CA); Schultz, Peter G. (La Jolla, CA)

2011-06-14T23:59:59.000Z

431

Tracking the Herd: Resynchronization Analysis of Cell-Cycle Gene Expression Data in Saccharomyces Cerevisiae  

E-Print Network [OSTI]

Tracking the Herd: Resynchronization Analysis of Cell-Cycle Gene Expression Data in Saccharomyces Cerevisiae Peng Qiu, Z. Jane Wang2, and K. J. Ray Liu Department of Electrical and Computer Engineering, University of Maryland, College Park, USA 2 Department of Electrical and Computer Engineering, University

Liu, K. J. Ray

432

OPEN CALL FOR EXPRESSIONS OF INTEREST For candidates for the position of  

E-Print Network [OSTI]

OPEN CALL FOR EXPRESSIONS OF INTEREST For candidates for the position of Nominee ITER Principal be an advantage. Languages: a thorough knowledge of English is essential and a working knowledge of French would programme. Interested candidates should send, either by e-mail or surface mail, their applications

433

NANO EXPRESS Open Access Ultrafast nano-oscillators based on interlayer-  

E-Print Network [OSTI]

NANO EXPRESS Open Access Ultrafast nano-oscillators based on interlayer- bridged carbon nanoscrolls nano-oscillators based on carbon nanoscrolls (CNSs) using molecular dynamics simulations. Initiated of gigahertz. We demonstrate an effective strategy to reduce the dissipation of the CNS-based nano

Li, Teng

434

NANO EXPRESS Open Access Resonant frequency of gold/polycarbonate hybrid  

E-Print Network [OSTI]

NANO EXPRESS Open Access Resonant frequency of gold/polycarbonate hybrid nano resonators fabricated on plastics via nano-transfer printing Edward Dechaumphai1 , Zhao Zhang1 , Nathan P Siwak2,3 , Reza Ghodssi2,3 , Teng Li1,4* Abstract We report the fabrication of gold/polycarbonate (Au/PC) hybrid nano resonators

Li, Teng

435

Module No: 420335Expression and legal draftingModule Title: Co-requisite:Pre-requisite  

E-Print Network [OSTI]

Hours Lecture Time Programme of Study: Daytime & Evening Study E-mailOffice Number Office Phone Academic rank Instructor Name E-mailOffice Number Office Phone Academic rank Module coordinator F legal research papers, articles and expressions in compliance with scientific methodology 3. enable

436

The expressiveness of CSP extended by priority A.W. Roscoe  

E-Print Network [OSTI]

The expressiveness of CSP extended by priority (draft) A.W. Roscoe Oxford University Department of Computer Science October 17, 2014 Abstract In previous work [27, 26] the author defined a notion of CSP with such an operational semantics can be translated into CSP and therefore has a semantics in every model of CSP

Oxford, University of

437

Research article Differential expression of heat shock protein genes in preconditioning  

E-Print Network [OSTI]

Research article Differential expression of heat shock protein genes in preconditioning February 2010 Keywords: GRP94 HSP70 Promoter analysis sHSP a b s t r a c t Heat shock proteins (HSPs) are induced not only under heat stress conditions but also under other environmental stresses such as water

Ramakrishnan, Naren

438

Invertebrate Neuroscience, 1, 341-349 (1996) Expression profiling of mRNA obtained from single  

E-Print Network [OSTI]

. COOPER 1, HAROLD L. ATWOOD 1 and DAVID R. HAMPSON Faculty of Pharmacy and Department of Physiology1, MRC in the levels of expression of known mRNAs in neurons that have been subjected to increased levels of electrical for the regulation of potentially interesting mRNks, under various experi- mental conditions, in species different

Cooper, Robin L.

439

Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc  

E-Print Network [OSTI]

Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein processes. Infusions of the -adrenoreceptor agonist, clen- buterol, into the BLA immediately after training increased Arc protein levels in the dorsal hippocampus. Additionally, posttraining intra-BLA infusions

O'Toole, Alice J.

440

Expression and Trans-Specific Polymorphism of Self-Incompatibility RNases in Coffea (Rubiaceae)  

E-Print Network [OSTI]

Expression and Trans-Specific Polymorphism of Self- Incompatibility RNases in Coffea (Rubiaceae Recherche ``Re´sistance des Plantes aux Bioagresseurs'', Montpellier, France Abstract Self-incompatibility understory trees in which the vast majority of diploid species utilize a mechanism of gametophytic self-incompatibility

Yoder, Anne

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Novel regulatory cascades controlling expression of nitrogen-fixation genes in Geobacter sulfurreducens  

E-Print Network [OSTI]

in these environments. Moreover, Geobacter species show promise for harvesting electricity from waste organic matterNovel regulatory cascades controlling expression of nitrogen-fixation genes in Geobacter Geobacter species often play an important role in bioremediation of environments contaminated with metals

Lovley, Derek

442

Enhanced Expression and Hydrogen Peroxide Dependence of Lignin Peroxidase from Streptomyces viridosporus T7A  

E-Print Network [OSTI]

Enhanced Expression and Hydrogen Peroxide Dependence of Lignin Peroxidase from Streptomyces of Streptomyces viridosporus T7A lignin peroxidase isoform ALiP-P3 were increased by formulating a novel corn analysis. In addition, the lignin peroxidase activity was found to be highly dependent upon

Wood, Thomas K.

443

EXPRESSION OF BRUCELLA GENES REQUIRED FOR LIPOPOLYSACCARIDE PRODUCTION UNDER THE CONTROL OF ARAC AND PTAC PROMOTERS  

E-Print Network [OSTI]

virulence mechanism in Brucella. The main objective of this project was to design an inducible system that would allow or prevent the expression of LPS using the manBA genes which encode components of LPS through the regulation of different promoters, p...

Han, Shuo

2006-08-16T23:59:59.000Z

444

Systems for the expression of orthogonal translation components eubacterial host cells  

DOE Patents [OSTI]

The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.

Ryu, Youngha (San Diego, CA); Schultz, Peter G. (La Jolla, CA)

2012-06-12T23:59:59.000Z

445

Protein Expression: freshly transform pInt DNA into BL21 strain  

E-Print Network [OSTI]

Protein Expression: freshly transform pInt DNA into BL21 strain pick an isolated colony which facilitates easy transfer transfer to a 30mL homogenizer (glass mortar and teflon pestle type at 45,000 rpm for 45 minutes at 4C transfer supernatant to new tube quick freeze in dry ice/EtOH bath

Segall, Anca

446

Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitus  

SciTech Connect (OSTI)

Chronic exposure to high concentrations of arsenic in drinking water is associated with an increased risk for developing type 2 diabetes. The present revision focuses on the effect of arsenic on tissues that participate directly in glucose homeostasis, integrating the most important published information about the impairment of the expression of genes related to type 2 diabetes by arsenic as one of the possible mechanisms by which it leads to the disease. Many factors are involved in the manner in which arsenic contributes to the occurrence of diabetes. The reviewed studies suggest that arsenic might increase the risk for type 2 diabetes via multiple mechanisms, affecting a cluster of regulated events, which in conjunction trigger the disease. Arsenic affects insulin sensitivity in peripheral tissue by modifying the expression of genes involved in insulin resistance and shifting away cells from differentiation to the proliferation pathway. In the liver arsenic disturbs glucose production, whereas in pancreatic beta-cells arsenic decreases insulin synthesis and secretion and reduces the expression of antioxidant enzymes. The consequences of these changes in gene expression include the reduction of insulin secretion, induction of oxidative stress in the pancreas, alteration of gluconeogenesis, abnormal proliferation and differentiation pattern of muscle and adipocytes as well as peripheral insulin resistance.

Diaz-Villasenor, Andrea [Department of Genomic Medicine and Environmental Toxicology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Circuito Escolar, Cd. Universitaria, Coyoacan 04510 Mexico, DF (Mexico)], E-mail: andreadv@biomedicas.unam.mx; Burns, Anna L. [Department of Genomic Medicine and Environmental Toxicology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Circuito Escolar, Cd. Universitaria, Coyoacan 04510 Mexico, DF (Mexico); Facultad de Medicina, Universidad Nacional Autonoma de Mexico (Mexico); Hiriart, Marcia [Department of Biophysics, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico (Mexico); Cebrian, Mariano E. [Seccion Externa de Toxicologia, CINVESTAV, IPN (Mexico); Ostrosky-Wegman, Patricia [Department of Genomic Medicine and Environmental Toxicology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Circuito Escolar, Cd. Universitaria, Coyoacan 04510 Mexico, DF (Mexico)

2007-12-01T23:59:59.000Z

447

Limitations and Trade-offs in Gene Expression due to Competition for Shared Cellular Resources  

E-Print Network [OSTI]

Limitations and Trade-offs in Gene Expression due to Competition for Shared Cellular Resources- lational resources in the cell. The fact that these common resources are available only in limited amounts, and surprisingly, as activators to each other, purely due to the limited availability of shared cellular resources

Del Vecchio, Domitilla

448

A Maximum Entropy Algorithm for Rhythmic Analysis of Genome-Wide Expression Patterns  

E-Print Network [OSTI]

A Maximum Entropy Algorithm for Rhythmic Analysis of Genome-Wide Expression Patterns Christopher James Langmead C. Robertson McClung Bruce Randall Donald ,,,§,¶ Abstract We introduce a maximum entropy-based spectral analysis, maximum entropy spectral reconstruction is well suited to signals of the type generated

Richardson, David

449

Systems for the expression of orthogonal translation components in eubacterial host cells  

DOE Patents [OSTI]

The invention related to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural acids at genetically-programmed positions.

Ryu, Youngha; Schultz, Peter G.

2013-01-22T23:59:59.000Z

450

Transcriptional and Posttranscriptional Regulation of Arabidopsis TCH4 Expression by Diverse Stimuli.  

E-Print Network [OSTI]

-1, respectively. Plants are sensitive to a number of abiotic environ- mental stimuli including light, wind in response to light stimuli (Ma et al., 2001), others that show elevated expression in extreme heat (Sung et- tion pathways are utilized in response to alterations in light and different temperature extremes

Braam, Janet

451

Expression of Ethanol-Induced Behavioral Sensitization Is Associated with Alteration of Chromatin Remodeling in  

E-Print Network [OSTI]

Expression of Ethanol-Induced Behavioral Sensitization Is Associated with Alteration of Chromatin), Amiens, France Abstract Background: Ethanol-induced behavioral sensitization (EIBS) is proposed to play in the development and the persistence of ethanol-related behaviors, we explored the involvement of epigenetic

Boyer, Edmond

452

Activation of calcium-sensing receptor increases TRPC3 expression in rat cardiomyocytes  

SciTech Connect (OSTI)

Research highlights: {yields} Calcium-sensing receptor (CaR) activation stimulates TRP channels. {yields} CaR promoted transient receptor potential C3 (TRPC3) expression. {yields} Adult rat ventricular myocytes display capacitative calcium entry (CCE), which was operated by TRPCs. {yields} TRPC channels activation induced by CaR activator sustained the increased [Ca{sup 2+}]{sub i} to evoke cardiomyocytes apoptosis. -- Abstract: Transient receptor potential (TRP) channels are expressed in cardiomyocytes, which gate a type of influx of extracellular calcium, the capacitative calcium entry. TRP channels play a role in mediating Ca{sup 2+} overload in the heart. Calcium-sensing receptors (CaR) are also expressed in rat cardiac tissue and promote the apoptosis of cardiomyocytes by Ca{sup 2+} overload. However, data about the link between CaR and TRP channels in rat heart are few. In this study, reverse transcriptase polymerase chain reaction (RT-PCR) and Western blotting were used to examine the expression of the TRP canonical proteins TRPC1 and TRPC3 in adult and neonatal rat cardiomyocytes. Laser scan confocal microscopy was used to detect intracellular [Ca{sup 2+}]{sub i} levels in isolated adult rat ventricular myocytes. The results showed that, in adult rat cardiomyocytes, the depletion of Ca{sup 2+} stores in the endoplasmic/sarcoplasmic reticulum (ER/SR) by thapsigargin induced a transient increase in [Ca{sup 2+}]{sub i} in the absence of [Ca{sup 2+}]{sub o} and the subsequent restoration of [Ca{sup 2+}]{sub o} sustained the increased [Ca{sup 2+}]{sub i} for a few minutes, whereas, the persisting elevation of [Ca{sup 2+}]{sub i} was reduced in the presence of the TRPC inhibitor SKF96365. The stimulation of CaR by its activator gadolinium chloride (GdCl{sub 3}) or spermine also resulted in the same effect and the duration of [Ca{sup 2+}]{sub i} increase was also shortened in the absence of [Ca{sup 2+}]{sub o}. In adult and neonatal rat cardiomyocytes, GdCl{sub 3} increased the expression of TRPC3 mRNA and protein, which were reversed by SKF96365 but not by inhibitors of the L-type channels and the Na{sup +}/Ca{sup 2+} exchangers. However, GdCl{sub 3} had no obvious effect on the expression of TRPC1 protein. These results suggested that CaR stimulation induced activation of TRP channels and promoted the expression of TRPC3, but not TRPC1, that sustained the increased [Ca{sup 2+}]{sub i}.

Feng, Shan-Li [Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086 (China)] [Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086 (China); Sun, Ming-Rui [Department of Pharmacology, Qiqihaer Medical College, Qiqihaer 160001 (China)] [Department of Pharmacology, Qiqihaer Medical College, Qiqihaer 160001 (China); Li, Ting-Ting; Yin, Xin [Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086 (China)] [Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086 (China); Xu, Chang-Qing [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China)] [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Sun, Yi-Hua, E-mail: syh200415@126.com [Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086 (China)] [Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086 (China)

2011-03-11T23:59:59.000Z

453

Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice  

SciTech Connect (OSTI)

Clinical hypothyroidism affects various metabolic processes including drug metabolism. CYP2B and CYP3A are important cytochrome P450 drug metabolizing enzymes that are regulated by the xenobiotic receptors constitutive androstane receptor (CAR, NR1I3) and pregnane X receptor (PXR, NR1I2). We evaluated the regulation of the hepatic expression of CYPs by CAR and PXR in the hypothyroid state induced by a low-iodine diet containing 0.15% propylthiouracil. Expression of Cyp3a11 was suppressed in hypothyroid C57BL/6 wild type (WT) mice and a further decrement was observed in hypothyroid CAR{sup ?/?} mice, but not in hypothyroid PXR{sup ?/?} mice. In contrast, expression of Cyp2b10 was induced in both WT and PXR{sup ?/?} hypothyroid mice, and this induction was abolished in CAR{sup ?/?} mice and in and CAR{sup ?/?} PXR{sup ?/?} double knockouts. CAR mRNA expression was increased by hypothyroidism, while PXR expression remained unchanged. Carbamazepine (CBZ) is a commonly used antiepileptic that is metabolized by CYP3A isoforms. After CBZ treatment of normal chow fed mice, serum CBZ levels were highest in CAR{sup ?/?} mice and lowest in WT and PXR{sup ?/?} mice. Hypothyroid WT or PXR{sup ?/?} mice survived chronic CBZ treatment, but all hypothyroid CAR{sup ?/?} and CAR{sup ?/?} PXR{sup ?/?} mice died, with CAR{sup ?/?}PXR{sup ?/?} mice surviving longer than CAR{sup ?/?} mice (12.3 ± 3.3 days vs. 6.3 ± 2.1 days, p = 0.04). All these findings suggest that hypothyroid status affects xenobiotic metabolism, with opposing responses of CAR and PXR and their CYP targets that can cancel each other out, decreasing serious metabolic derangement in response to a xenobiotic challenge. -- Highlights: ? Hypothyroid status activates CAR in mice and induces Cyp2b10 expression. ? Hypothyroid status suppresses PXR activity in mice and represses Cyp3a11 expression. ? These responses balance each other out in normal mice. ? Hypothyroidism sensitizes CAR null mice to toxic effects of carbamazepine.

Park, Young Joo [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of) [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of); Seoul National University Bundang Hospital, Seoul (Korea, Republic of); Lee, Eun Kyung [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of)] [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of); Lee, Yoon Kwang [Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (United States)] [Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (United States); Park, Do Joon; Jang, Hak Chul [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of)] [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of); Moore, David D., E-mail: moore@bcm.edu [Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (United States)

2012-09-01T23:59:59.000Z

454

Real-Time Gene Expression Profiling of Live Shewanella Oneidensis Cells  

SciTech Connect (OSTI)

The overall objective of this proposal is to make real-time observations of gene expression in live Shewanella oneidensis cells with high sensitivity and high throughput. Gene expression, a central process to all life, is stochastic because most genes often exist in one or two copies per cell. Although the central dogma of molecular biology has been proven beyond doubt, due to insufficient sensitivity, stochastic protein production has not been visualized in real time in an individual cell at the single-molecule level. We report the first direct observation of single protein molecules as they are generated, one at a time in a single live E. coli cell, yielding quantitative information about gene expression [Science 2006; 311: 1600-1603]. We demonstrated a general strategy for live-cell single-molecule measurements: detection by localization. It is difficult to detect single fluorescence protein molecules inside cytoplasm - their fluorescence is spread by fast diffusion to the entire cell and overwhelmed by the strong autofluorescence. We achieved single-molecule sensitivity by immobilizing the fluorescence protein on the cell membrane, where the diffusion is much slowed. We learned that under the repressed condition protein molecules are produced in bursts, with each burst originating from a stochastically-transcribed single messenger RNA molecule, and that protein copy numbers in the bursts follow a geometric distribution. We also simultaneously published a paper reporting a different method using ?-glactosidase as a reporter [Nature 440, 358 (2006)]. Many important proteins are expressed at low levels, inaccessible by previous proteomic techniques. Both papers allowed quantification of protein expression with unprecedented sensitivity and received overwhelming acclaim from the scientific community. The Nature paper has been identified as one of the most-cited papers in the past year [http://esi-topics.com/]. We have also an analytical framework describing the steady-state distribution of protein concentration in live cells, considering that protein production occurs in random bursts with an exponentially distributed number of molecules. This model allows for the extraction of kinetic parameters of gene expression from steady-state distributions of protein concentration in a cell population, which are available from single cell data obtained by fluorescence microscopy. [Phys. Rev. Lett. 97, 168302 (2006)]. A major objective in the Genome to Life (GtL) program is to monitor and understand the gene expression profile of a complete bacterial genome. We developed genetic and imaging methods for sensitive protein expression profiling in individual S. oneidensis cell. We have made good progress in constructing YFP-library with several hundred chromosomal fusion proteins and studied protein expression profiling in living Shewanella oneidensis cells. Fluorescence microscopy revealed the average abundance of specific proteins, as well as their noise in gene expression level across a population. We also explored ways to adapt our fluorescence measurement for other growth conditions, such as anaerobic growth.

Xiaoliang Sunney Xie

2009-03-30T23:59:59.000Z

455

Nucleic and amino acid sequences relating to a novel transketolase, and methods for the expression thereof  

DOE Patents [OSTI]

cDNAs encoding 1-deoxyxylulose-5-phosphate synthase from peppermint (Mentha piperita) have been isolated and sequenced, and the corresponding amino acid sequences have been determined. Accordingly, isolated DNA sequences (SEQ ID NO:3, SEQ ID NO:5, SEQ ID NO:7) are provided which code for the expression of 1-deoxyxylulose-5-phosphate synthase from plants. In another aspect the present invention provides for isolated, recombinant DXPS proteins, such as the proteins having the sequences set forth in SEQ ID NO:4, SEQ ID NO:6 and SEQ ID NO:8. In other aspects, replicable recombinant cloning vehicles are provided which code for plant 1-deoxyxylulose-5-phosphate synthases, or for a base sequence sufficiently complementary to at least a portion of 1-deoxyxylulose-5-phosphate synthase DNA or RNA to enable hybridization therewith. In yet other aspects, modified host cells are provided that have been transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence encoding a plant 1-deoxyxylulose-5-phosphate synthase. Thus, systems and methods are provided for the recombinant expression of the aforementioned recombinant 1-deoxyxylulose-5-phosphate synthase that may be used to facilitate its production, isolation and purification in significant amounts. Recombinant 1-deoxyxylulose-5-phosphate synthase may be used to obtain expression or enhanced expression of 1-deoxyxylulose-5-phosphate synthase in plants in order to enhance the production of 1-deoxyxylulose-5-phosphate, or its derivatives such as isopentenyl diphosphate (BP), or may be otherwise employed for the regulation or expression of 1-deoxyxylulose-5-phosphate synthase, or the production of its products.

Croteau, Rodney Bruce (Pullman, WA); Wildung, Mark Raymond (Colfax, WA); Lange, Bernd Markus (Pullman, WA); McCaskill, David G. (Pullman, WA)

2001-01-01T23:59:59.000Z

456

The Express  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched Ferromagnetism in Layered NbS2 and NbSe2Different ImpactsThe EnergyRC25406LACED

457

IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS--II: EXPRESS BRIEFS, VOL. 55, NO. 4, APRIL 2008 297 Guest Editorial  

E-Print Network [OSTI]

IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS--II: EXPRESS BRIEFS, VOL. 55, NO. 4, APRIL 2008 297 Guest of multiple standards, indi- cates a great opportunity for adoption of wireless technology at a mass-market TRANSACTIONS ON CIRCUITS AND SYSTEMS--II: EXPRESS BRIEFS for their efforts in creating this Special Issue. We

Serdijn, Wouter A.

458

Expressing a Tensor Permutation Matrix $p^{\\otimes n}$ in Terms of the Generalized Gell-Mann Matrices  

E-Print Network [OSTI]

We have shown how to express a tensor permutation matrix $p^{\\otimes n}$ as a linear combination of the tensor products of the $p\\times p$-Gell-Mann matrices. We have given the expression of a tensor permutation matrix $2\\otimes 2 \\otimes 2$ as a linear combination of the tensor products of the Pauli matrices.

Rakotonirina Christian

2006-03-30T23:59:59.000Z

459

MicroRNAs Function as Cis- and Trans- Acting Modulators of Clock Gene Expression in SCN and Peripheral Circadian Oscillators  

E-Print Network [OSTI]

RNAs) predicted to target Bmal1. We profiled the temporal expression of miR-142-3p in the mouse SCN in vivo and in an immortalized SCN cell line and observed robust circadian rhythms in its expression in the SCN. Following luciferase-reporter and site...

Shende, Vikram Ravindra 1982-

2012-11-15T23:59:59.000Z

460

Expressive language in male adolescents with fragile X syndrome with and without comorbid autismjir_1255 246..265  

E-Print Network [OSTI]

-specificity of the expressive language impairment of both groups of those with FXS was assessed in relation to Down syndrome with FXS without autism (n = 20), comorbid FXS and autism (n = 8), and Down syndrome (n = 16). Syntactic by the context in which their talk occurs. Keywords fragile X syndrome, Down Syndrome, autism, expressive

Nguyen, Danh

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Silencing of SPC2 Expression Using an Engineered Ribozyme in the Mouse TC-3 Endocrine Cell Line*  

E-Print Network [OSTI]

Silencing of SPC2 Expression Using an Engineered Ribozyme in the Mouse TC-3 Endocrine Cell Line the distinct roles of a member of this family (SPC2), gene silencing in cultured cells is an ideal approach to establish TC-3 stable cell lines expressing the chimeric tRNAVal - ribozyme transcript targeting SPC2 m

Perreault, Jean-Pierre

462

ETUDE DE L'INFLUENCE DES POLYMORPHISMES GENETIQUES SUR LE PROFIL D'EXPRESSION DES GNES PAR DES MTHODES  

E-Print Network [OSTI]

polymorphismes) pour tester les liens entre patrimoine génétique et les différences phénotypiques à l expression level to make the search for large scale genotypic effect easier. The proposed method relies on the unsupervised extraction of relevant patterns using independent component analysis and the search for expression

Paris-Sud XI, Université de

463

Structure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence for the existence of  

E-Print Network [OSTI]

Structure and expression of the maize (Zea mays L.) SUN- domain protein gene family: evidence for the existence of two divergent classes of SUN proteins in plants Murphy et al. Murphy et al. BMC Plant Biology Access Structure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence

Bass, Hank W.

464

Expression and function of phospholipase A2 in brain Mar|a A. Balboa1;2  

E-Print Network [OSTI]

by Edward A. Dennis, Isabel Varela-Nieto and Alicia Alonso Abstract Phospholipase A2 (PLA2) appears to play a funda- mental role in cell injury in the central nervous system. We have investigated PLA2 expression in the astrocytoma cell line 1231N1, and found that GIVA, GIVB, GIVC and GVI PLA2 messages are expressed. PLA2

Dennis, Edward A.

465

Phosphatidylinositol 4-Phosphate 5-Kinase Reduces Cell Surface Expression of the Epithelial Sodium Channel (ENaC)  

E-Print Network [OSTI]

Phosphatidylinositol 4-Phosphate 5-Kinase Reduces Cell Surface Expression of the Epithelial Sodium levels and reduced apical surface expression of ENaC in CCD cells, down-regulating amiloride- sensitive Channel (ENaC) in Cultured Collecting Duct Cells* Received for publication,May 14, 2007, and in revised

Weisz, Ora A.

466

Voice quality and f0 cues for affect expression: implications for synthesis Irena Yanushevskaya, Christer Gobl & Ailbhe N Chasaide  

E-Print Network [OSTI]

variation in both voice quality and affect-related f0 contours. A total of 15 stimuli were rated for 12Voice quality and f0 cues for affect expression: implications for synthesis Irena Yanushevskaya-of-voice ­ voice quality and fundamental frequency ­ are involved in the expression of affect. Listeners were

Hirschberg, Julia

467

Selective effect of the metallocarcinogen beryllium on hormonal regulation of gene expression in cultured cells  

SciTech Connect (OSTI)

Effects of the metallocarcinogen beryllium on regulation of gene expression were assessed by analysis of hormonal regulation of synthesis of tyrosine aminotransferase in beryllium-treated hepatoma cell cultures. Cell growth was not affected by exposure of the cells to 1 ..mu..M BeSO/sub 4/ throughout their 4- to 5-day growth cycle. In cells pretreated in this way, the induction by glucocorticoids was specifically impaired, the extent of induced enzyme synthesis being reduced about 50%. Inductions by insulin or cyclic adenosine 3':5'-monophosphate were not influenced by the metal. The results suggest that low concentrations of beryllium selectively interfere with regulatory mechanisms controlling transcriptional events in gene expression.

Perry, S.T.; Kulkarni, S.B.; Lee, K.L.; Kenney, F.T.

1982-02-01T23:59:59.000Z

468

Design and expression of a short peptide as an HIV detection probe  

SciTech Connect (OSTI)

Highlights: •We designed a short fusion peptide (FP-50) for in vivo expression. •This peptide is a very promising component for detection of gp120 protein. •The detectable level is about 20–200 times lower than previously published methods. •It is a novel probe to detect HIV-1 gp120 during early stages of HIV infection. -- Abstract: To explore a low-cost novel probe for HIV detection, we designed and prepared a 50-amino acid-length short fusion peptide (FP-50) via Escherichia coli in vivo expression. It was employed as a novel probe to detect HIV-1 gp120 protein. The detectable level of gp120 protein using the FP-50 peptide was approximately 20–200 times lower than previously published methods that used a pair of monoclonal antibodies. Thus, this short peptide is a very promising component for detection of gp120 protein during early stages of HIV infection.

Lines, Jamie A.; Yu, Zhiqiang; Dedkova, Larisa M.; Chen, Shengxi, E-mail: shengxi.chen.1@asu.edu

2014-01-03T23:59:59.000Z

469

Process and genes for expression and overexpression of active [FeFe] hydrogenases  

DOE Patents [OSTI]

A process for expression of active [FeFe]-hydrogenase in a host organism that does not contain either the structural gene(s) for [FeFe]-hydrogenases and/or homologues for the maturation genes HydE, HydF and HyG, comprising: cloning the structural hydrogenase gene(s) and/or the maturation genes HydE, HydF and HydG from an organisms that contains these genes into expression plasmids; transferring the plasmids into an organism that lacks a native [FeFe]-hydrogenase or that has a disrupted [FeFe]-hydrogenase and culturing it aerobically; and inducing anaerobiosis to provide [FeFe] hydrogenase biosynthesis and H?2#191 production.

Seibert, Michael; King, Paul W; Ghirardi, Maria Lucia; Posewitz, Matthew C; Smolinski, Sharon L

2014-09-16T23:59:59.000Z

470

Computational processes of evolution and the gene expression messy genetic algorithm  

SciTech Connect (OSTI)

This paper makes an effort to project the theoretical lessons of the SEARCH (Search Envisioned As Relation and Class Hierarchizing) framework introduced elsewhere (Kargupta, 1995b) in the context of natural evolution and introduce the gene expression messy genetic algorithm (GEMGA) -- a new generation of messy GAs that directly search for relations among the members of the search space. The GEMGA is an O({vert_bar}{Lambda}{vert_bar}{sup k}({ell} + k)) sample complexity algorithm for the class of order-k delineable problems (Kargupta, 1995a) (problems that can be solved by considering no higher than order-k relations) in sequence representation of length {ell} and alphabet set {Lambda}. Unlike the traditional evolutionary search algorithms, the GEMGA emphasizes the computational role of gene expression and uses a transcription operator to detect appropriate relations. Theoretical conclusions are also substantiated by experimental results for large multimodal problems with bounded inappropriateness of representation.

Kargupta, H. [Los Alamos National Lab., NM (United States). Computational Science Methods Div.

1996-05-01T23:59:59.000Z

471

Entanglement-assisted Enhanced Information Transmission Over a Quantum Channel with Correlated Noise; A General Expression  

E-Print Network [OSTI]

Entanglement and entanglement-assisted are useful resources to enhance the mutual information of the Pauli channels, when the noise on consecutive uses of the channel has some partial correlations. In this paper, We study quantum communication channels with correlated noise and derive a general expression for the mutual information of quantum channel, for the product, maximally entangled state coding and entanglement-assisted systems with correlated noise in the Pauli quantum channels. Hence, we suggest more efficient coding in the entanglement-assisted systems for the transmission of classical information and derive a general expression for the entanglement-assisted classical capacity. Our results show that in the presence of memory, a higher amount of classical information is transmitted by two or four consecutive uses of entanglement-assisted systems.

A. Fahmi

2006-05-04T23:59:59.000Z

472

Expression of lip genes during growth in soil and oxidation of anthracene by Phanerochaete chrysosporium  

SciTech Connect (OSTI)

mRNA extraction from soil and quantitation by competitive reverse transcription-PCR were combined to study the expression of the 10 known lignin peroxidase (lip) genes in anthracene-transforming soil cultures of Phanerochaete chrysosporium. Levels of extractable lipA transcript and protein (LiP H8) were well correlated, although they were separated by a 2-day lag period. The patterns of transcript abundance over time in soil-grown P. chrysosporium varied among the nine lip mRNAs detected; comparison with lip gene expression under different liquid culture conditions suggested an early phase of carbon limitation for the cultures as a whole, which was followed by a transition to nitrogen starvation. Anthracene transformation occurred through-out the 25-day course of the experiment and, therefore, likely involves mechanisms distinct from those involved in oxidation of non-LiP substrate polycyclic aromatic hydrocarbons. 54 refs., 6 figs.

Bogan, B.W. [Univ. of Wisconsin, Madison, WI (United States); Schoenike, B.; Lamar, R.T.; Cullen, D. [Inst. for Microbial and Biochemical Technology, Madison, WI (United States)

1996-10-01T23:59:59.000Z

473

Express Letter Fullerene-like carbon nanostructures in the Allende meteorite  

E-Print Network [OSTI]

Express Letter Fullerene-like carbon nanostructures in the Allende meteorite P.J.F. Harris aY *, R 0 1 2 - 8 2 1 X ( 0 0 ) 0 0 2 7 7 - 6 * Corresponding author. E-mail: p.j.f.harris@rdg.ac.uk Earth. Higher magni¢cation image showing structure of carbon. P.J.F. Harris et al. / Earth and Planetary Science

Harris, Peter J F

474

Uterine Biology of the Pig: Gene Expression for Establishment of Pregnancy  

E-Print Network [OSTI]

collection Uteri obtained from sexually mature female pigs (gilts) were obtained on Days 11, 13, 15 and 17 of pregnancy and the estrous cycle was used for this experiment. The samples were obtained from the United States Department of Agriculture Meat... and pregnancy status on expression of oxytocin and oxytocin receptors in uteri of pregnant and cyclic gilts. The gilts were oophorectomize- hysterectomized on Day 11, 13, 15 or 17 of the estrous cycle and Day 11, 13, 15 or 17 of pregnancy...

Brown, Gladys

2013-09-25T23:59:59.000Z

475

Creativity, expression, and healing: an empirical study using mandalas within the written disclosure paradigm  

E-Print Network [OSTI]

CREATIVITY, EXPRESSION, AND HEALING: AN EMPIRICAL STUDY USING MANDALAS WITHIN THE WRITTEN DISCLOSURE PARADIGM A Thesis by PATTI GAIL HENDERSON Submitted to the Office of Graduate Studies of Texas A&M University... DISCLOSURE PARADIGM A Thesis by PATTI GAIL HENDERSON Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved by: Chair...

Henderson, Patti Gail

2009-05-15T23:59:59.000Z

476

Expression of Candidate Genes for Horn Growth in Early Bovine Development  

E-Print Network [OSTI]

of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved by: Co-hairs of Committee, Clare A. Gill Penny K. Riggs Committee Member James O. Sanders Head of Department,Gary Acuff December... EXPRESSION OF CANDIDATE GENES FOR HORN GROWTH IN EARLY BOVINE DEVELOPMENT A Thesis by SARAH M. VITANZA Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements...

Vitanza, Sarah M.

2011-02-22T23:59:59.000Z

477

Pubertal changes in the expression of fertility associated antigen in Bos indicus and Bos taurus bulls  

E-Print Network [OSTI]

PUBERTAL CHANGES IN THE EXPRESSION OF FERTILITY ASSOCIATED ANTIGEN IN BOS INDICUS AND BOS TAURUS BULLS A Thesis by AARON M. NOVOSAD Submitted to the Office of Graduate Studies of Texas A&M University in partial... TAURUS BULLS A Thesis by AARON M. NOVOSAD Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved by: Co...

Novosad, Aaron M.

2007-04-25T23:59:59.000Z

478

Changes in protein expression in maturing equine testis: a quantitative DIGE analysis  

E-Print Network [OSTI]

in -80 o C while awaiting mass spectrometric analysis. LC/MS/MS analysis and database search Nanospray LC/MS/MS was performed on an LCQ DecaXP 3D Ion Trap Mass Spectrometer (ThermoFinnigan, San Jose, CA). Extracted peptides were concentrated... CHANGES IN PROTEIN EXPRESSION IN MATURING EQUINE TESTIS: A QUANTITATIVE DIGE ANALYSIS Major: Genetics April 2009 Submitted to the Office of Undergraduate Research Texas A&M University in partial fulfillment...

Roper-Foo, Pilar

2011-01-11T23:59:59.000Z

479

Disruption of DNA methylation induces genome-specific changes in gene expression in Arabidopsis allotetraploids  

E-Print Network [OSTI]

the contrib- uted genomes of the new polyploid are meiotically recombinant or nonrecombinant, re- spectively, where the meiotic behavior reflects genome ?divergence?. Polyploidy is a prominent phenomenon among plants. 1Around 95% of angiosperms and 70... that govern gene expression in polyploids. The subspecies Arabidopsis thaliana and A. arenosa diverged from each other ~5.8 Mya and share more than 95% similarity in genomic sequence (Koch et al., 2001). Interspecific hybridization can occur between...

Chen, Meng

2007-04-25T23:59:59.000Z

480

Neurosciences Eddie Smith  

E-Print Network [OSTI]

Ambulatory Care Thurston Bowles Neurosciences MBRB Carolina Inn Paul Green Graham Davis Lib Eddie Smith Field

Lieb, Jason

Note: This page contains sample records for the topic "holiday inn express" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Message from Dean A new semester and a new year are upon us. The transition from the quiet holiday season campus to the hustle and bustle of  

E-Print Network [OSTI]

all our buildings as well as attention to new facility needs across the College to create a 21st in sustaining and enhancing natural resources, the environment and human well being." We look forward to you as Geographic Analogs: Testing, Training and Sustainability Considerations for Worldwide Operating Environments

482

Better Buildings Residential Network Driving Demand Peer Exchange Call Series: Leveraging Holidays and Other Events Call Slides and Discussion Summary, November 7, 2013  

Broader source: Energy.gov (indexed) [DOE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists' ResearchTheMarketing,Energy and NaturalBethel Valley

483

Nonspecific transcription factor binding reduces variability in transcription factor and target protein expression  

E-Print Network [OSTI]

Transcription factors (TFs) interact with a multitude of binding sites on DNA and partner proteins inside cells. We investigate how nonspecific binding/unbinding to such decoy binding sites affects the magnitude and time-scale of random fluctuations in TF copy numbers arising from stochastic gene expression. A stochastic model of TF gene expression, together with decoy site interactions is formulated. Distributions for the total (bound and unbound) and free (unbound) TF levels are derived by analytically solving the chemical master equation under physiologically relevant assumptions. Our results show that increasing the number of decoy binding sides considerably reduces stochasticity in free TF copy numbers. The TF autocorrelation function reveals that decoy sites can either enhance or shorten the time-scale of TF fluctuations depending on model parameters. To understand how noise in TF abundances propagates downstream, a TF target gene is included in the model. Intriguingly, we find that noise in the expression of the target gene decreases with increasing decoy sites for linear TF-target protein dose-responses, even in regimes where decoy sites enhance TF autocorrelation times. Moreover, counterintuitive noise transmissions arise for nonlinear dose-responses. In summary, our study highlights the critical role of molecular sequestration by decoy binding sites in regulating the stochastic dynamics of TFs and target proteins at the single-cell level.

Mohammad Soltani; Pavol Bokes; Zachary Fox; Abhyudai Singh

2015-04-14T23:59:59.000Z

484

Gene expression profiling--Opening the black box of plant ecosystem responses to global change  

SciTech Connect (OSTI)

The use of genomic techniques to address ecological questions is emerging as the field of genomic ecology. Experimentation under environmentally realistic conditions to investigate the molecular response of plants to meaningful changes in growth conditions and ecological interactions is the defining feature of genomic ecology. Since the impact of global change factors on plant performance are mediated by direct effects at the molecular, biochemical and physiological scales, gene expression analysis promises important advances in understanding factors that have previously been consigned to the 'black box' of unknown mechanism. Various tools and approaches are available for assessing gene expression in model and non-model species as part of global change biology studies. Each approach has its own unique advantages and constraints. A first generation of genomic ecology studies in managed ecosystems and mesocosms have provided a testbed for the approach and have begun to reveal how the experimental design and data analysis of gene expression studies can be tailored for use in an ecological context.

Leakey, A.D.B.; Ainsworth, E.A.; Bernard, S.M.; Markelz, R.J.C.; Ort, D.R.; Placella, S.A.P.; Rogers, A.; Smith, M.D.; Sudderth, E.A.; Weston, D.J.; Wullschleger, S.D.; Yuan, S.

2009-11-01T23:59:59.000Z

485

Expression of aquaporin8 in human astrocytomas: Correlation with pathologic grade  

SciTech Connect (OSTI)

Highlights: •AQP8 is mainly distributed in the cytoplasm of human astrocytoma cells. •AQP8 over-expressed in human astrocytomas, especially glioblastoma. •The up-regulation of AQP8 is related to the pathological grade of human astrocytomas. •AQP8 may contribute to the growth and proliferation of astrocytomas. -- Abstract: Aquaporin8 (AQP8), a member of the aquaporin (AQP) protein family, is weakly distributed in mammalian brains. Previous studies on AQP8 have focused mainly on the digestive and the reproductive systems. AQP8 has a pivotal role in keeping the fluid and electrolyte balance. In this study, we investigated the expression changes of AQP8 in 75 cases of human brain astrocytic tumors using immunohistochemistry, Western blotting, and reverse transcription polymerase chain reaction. The results demonstrated that AQP8 was mainly distributed in the cytoplasm of astrocytoma cells. The expression levels and immunoreactive score of AQP8 protein and mRNA increased in low-grade astrocytomas, and further increased in high-grade astrocytomas, especially in glioblastoma. Therefore, AQP8 may contribute to the proliferation of astrocytomas, and may be a biomarker and candidate therapy target for patients with astrocytomas.

Zhu, Shu-juan; Wang, Ke-jian; Gan, Sheng-wei; Xu, Jin; Xu, Shi-ye; Sun, Shan-quan, E-mail: sunsq2151@cqmu.edu.cn

2013-10-11T23:59:59.000Z

486

Expression of HPV16 E5 produces enlarged nuclei and polyploidy through endoreplication  

SciTech Connect (OSTI)

Anogenital cancers and head and neck cancers are causally associated with infection by high-risk human papillomavirus (HPV). The mechanism by which high-risk HPVs contribute to oncogenesis is poorly understood. HPV16 encodes three genes (HPV16 E5, E6, and E7) that can transform cells when expressed independently. HPV16 E6 and E7 have well-described roles causing genomic instability and unregulated cell cycle progression. The role of HPV16 E5 in cell transformation remains to be elucidated. Expression of HPV16 E5 results in enlarged, polyploid nuclei that are dependent on the level and duration of HPV16 E5 expression. Live cell imaging data indicate that these changes do not arise from cell-cell fusion or failed cytokinesis. The increase in nuclear size is a continual process that requires DNA synthesis. We conclude that HPV16 E5 produces polyploid cells by endoreplication. These findings provide insight into how HPV16 E5 can contribute to cell transformation.

Hu Lulin [Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Potapova, Tamara A. [Cell Cycle and Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK (United States); Li Shibo [Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Rankin, Susannah; Gorbsky, Gary J. [Cell Cycle and Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK (United States); Angeletti, Peter C. [Nebraska Center for Virology, University of Nebraska, Lincoln, NE (United States); Ceresa, Brian P., E-mail: brian-ceresa@oushc.ed [Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)

2010-09-30T23:59:59.000Z

487

Tocopherol Succinate: Modulation of Antioxidant Enzymes and Oncogene Expression, and Hematopoietic Recovery  

SciTech Connect (OSTI)

Purpose: A class of naturally occurring isoforms of tocopherol (tocols) was shown to have varying degrees of protection when administered before radiation exposure. We recently demonstrated that {alpha}-tocopherol succinate (TS) is a potential radiation prophylactic agent. Our objective in this study was to further investigate the mechanism of action of TS in mice exposed to {sup 60}Co {gamma}-radiation. Methods and Materials: We evaluated the effects of TS on expression of antioxidant enzymes and oncogenes by quantitative RT-PCR in bone marrow cells of {sup 60}Co {gamma}-irradiated mice. Further, we tested the ability of TS to rescue and repopulate hematopoietic stem cells by analyzing bone marrow cellularity and spleen colony forming unit in spleen of TS-injected and irradiated mice. Results: Our results demonstrate that TS modulated the expression of antioxidant enzymes and inhibited expression of oncogenes in irradiated mice at different time points. TS also increased colony forming unit-spleen numbers and bone marrow cellularity in irradiated mice. Conclusions: Results provide additional support for the observed radioprotective efficacy of TS and insight into mechanisms.

Singh, Vijay K., E-mail: singh@afrri.usuhs.mi [Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD (United States); Parekh, Vaishali I.; Brown, Darren S.; Kao, Tzu-Cheg [Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD (United States); Mog, Steven R. [Veterinary Sciences Department, Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD (United States)

2011-02-01T23:59:59.000Z

488

Fluctuations in Species-Level Protein Expression Occur during Element and Nutrient Cycling in the Subsurface  

SciTech Connect (OSTI)

While microbial activities in environmental systems play a key role in the utilization and cycling of essential elements and compounds, microbial activity and growth frequently fluctuates in response to environmental stimuli and perturbations. To investigate these fluctuations within a saturated aquifer system, we monitored a carbon-stimulated in situ Geobacter population while iron reduction was occurring, using 16S rRNA abundances and high-resolution tandem mass spectrometry proteome measurements. Following carbon amendment, 16S rRNA analysis of temporally separated samples revealed the rapid enrichment of Geobacter-like environmental strains with strong similarity to G. bemidjiensis. Tandem mass spectrometry proteomics measurements suggest high carbon flux through Geobacter respiratory pathways, and the synthesis of anapleurotic four carbon compounds from acetyl-CoA via pyruvate ferredoxin oxidoreductase activity. Across a 40-day period where Fe(III) reduction was occurring, fluctuations in protein expression reflected changes in anabolic versus catabolic reactions, with increased levels of biosynthesis occurring soon after acetate arrival in the aquifer. In addition, localized shifts in nutrient limitation were inferred based on expression of nitrogenase enzymes and phosphate uptake proteins. These temporal data offer the first example of differing microbial protein expression associated with changing geochemical conditions in a subsurface environment.

Wilkins, Michael J.; Wrighton, Kelly C.; Nicora, Carrie D.; Williams, Kenneth H.; McCue, Lee Ann; Handley, Kim M.; Miller, C. S.; Giloteaux, L.; Montgomery, A. P.; Lovley, Derek R.; Banfield, Jillian F.; Long, Philip E.; Lipton, Mary S.

2013-03-05T23:59:59.000Z

489

Regulating expression of cell and tissue-specific genes by modifying transcription  

SciTech Connect (OSTI)

Transcriptional regulation is the primary step to control gene expression, therefore function. Such regulation is achieved primarily via a combination of the activities of the promoter cis regulatory DNA elements and trans regulatory proteins that function through binding to these DNA elements. Rice bZIP transcription factors RF2a, RF2b and RLP1 play key roles in regulating the activity of a vascular tissue specific promoter isolated from Rice Tungro Bacilliform Virus (RTBV), through their interactions with the Box II essential cis element located in the promoter (Dai et al., 2006., Dai et al., 2004., Yin et al., 1997). RF2a, RF2b and RLP1 possess multiple regulatory domains. Functional characterization reveals that those domains can activate or repress the activity of the RTBV promoter. It is equally as important to recognize that these proteins control plant development by regulating differentiation and/or function of the vascular tissues. Studies of transcriptional regulation of the RTBV promoter by this group of bZIP proteins will not only provide insights about gene expression in the vascular tissue, but also insights about general mechanisms of transcription activation and repression. The knowledge gained from this research will also enable us to develop a well-described set of tools that can be used to control expression of multiple genes in transgenic plants. We have proposed characterize the function domains of RF2a, RF2b and RLP1 and explore the biological function of the transcription repressor RLP1.

Beachy, Roger N; Dai, Shunhong

2010-06-14T23:59:59.000Z

490

Mechanosensitivity of human osteosarcoma cells and phospholipase C {beta}2 expression  

SciTech Connect (OSTI)

Bone adapts to mechanical load by osteosynthesis, suggesting that osteoblasts might respond to mechanical stimuli. We therefore investigated cell proliferation and phospholipase C (PLC) expression in osteoblasts. One Hertz uniaxial stretching at 4000 {mu}strains significantly increased the proliferation rates of human osteoblast-like osteosarcoma cell line MG-63 and primary human osteoblasts. However, U-2/OS, SaOS-2, OST, and MNNG/HOS cells showed no significant changes in proliferation rate. We investigated the expression pattern of different isoforms of PLC in these cell lines. We were able to detect PLC {beta}1, {beta}3, {gamma}1, {gamma}2, and {delta}1 in all cells, but PLC {beta}2 was only detectable in the mechanosensitive cells. We therefore investigated the possible role of PLC {beta}2 in mechanotransduction. Inducible antisense expression for 24 h inhibited the translation of PLC {beta}1 in U-2/OS cells by 35% and PLC {beta}2 in MG-63 by 29%. Fluid shear flow experiments with MG-63 lacking PLC {beta}2 revealed a significantly higher level of cells losing attachment to coverslips and a significantly lower number of cells increasing intracellular free calcium.

Hoberg, M. [Department of Orthopaedics, University of Tuebingen (Germany)]. E-mail: Maik.Hoberg@med.uni-tuebingen.de; Gratz, H.-H. [Experimental Orthopaedics and Biomechanics, Phillips-University of Marburg (Germany); Noll, M. [Experimental Orthopaedics and Biomechanics, Phillips-University of Marburg (Germany); Jones, D.B. [Experimental Orthopaedics and Biomechanics, Phillips-University of Marburg (Germany)

2005-07-22T23:59:59.000Z

491

High expression of arachidonate 15-lipoxygenase and proinflammatory markers in human ischemic heart tissue  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer We found a 17-fold upregulation of ALOX15 in the ischemic heart. Black-Right-Pointing-Pointer Incubation of human muscle cells in hypoxia showed a 22-fold upregulation of ALOX15. Black-Right-Pointing-Pointer We observed increased levels of proinflammatory markers in ischemic heart tissue. Black-Right-Pointing-Pointer Suggesting a link between ischemia and inflammation in ischemic heart biopsies. -- Abstract: A common feature of the ischemic heart and atherosclerotic plaques is the presence of hypoxia (insufficient levels of oxygen in the tissue). Hypoxia has pronounced effects on almost every aspect of cell physiology, and the nuclear transcription factor hypoxia inducible factor-1{alpha} (HIF-1{alpha}) regulates adaptive responses to low concentrations of oxygen in mammalian cells. In our recent work, we observed that hypoxia increases the proinflammatory enzyme arachidonate 15-lipoxygenase (ALOX15B) in human carotid plaques. ALOX15 has recently been shown to be present in the human myocardium, but the effect of ischemia on its expression has not been investigated. Here we test the hypothesis that ischemia of the heart leads to increased expression of ALOX15, and found an almost 2-fold increase in HIF-1{alpha} mRNA expression and a 17-fold upregulation of ALOX15 mRNA expression in the ischemic heart biopsies from patients undergoing coronary bypass surgery compared with non ischemic heart tissue. To investigate the effect of low oxygen concentration on ALOX15 we incubated human vascular muscle cells in hypoxia and showed that expression of ALOX15 increased 22-fold compared with cells incubated in normoxic conditions. We also observed increased mRNA levels of proinflammatory markers in ischemic heart tissue compared with non-ischemic controls. In summary, we demonstrate increased ALOX15 in human ischemic heart biopsies. Furthermore we demonstrate that hypoxia increases ALOX15 in human muscle cells. Our results yield important insights into the underlying association between hypoxia and inflammation in the human ischemic heart disease.

Magnusson, Lisa U.; Lundqvist, Annika [Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg (Sweden)] [Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg (Sweden); Asp, Julia [Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg (Sweden)] [Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg (Sweden); Synnergren, Jane [Systems Biology Research Center, School of Life Sciences, University of Skoevde, Skoevde (Sweden)] [Systems Biology Research Center, School of Life Sciences, University of Skoevde, Skoevde (Sweden); Johansson, Cecilia Thalen [Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg (Sweden)] [Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg (Sweden); Palmqvist, Lars [Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg (Sweden)] [Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg (Sweden); Jeppsson, Anders [Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg (Sweden)] [Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg (Sweden); Hulten, Lillemor Mattsson, E-mail: Lillemor.Mattsson@wlab.gu.se [Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg (Sweden)

2012-07-27T23:59:59.000Z

492

Effect of metallothionein 2A gene polymorphism on allele-specific gene expression and metal content in prostate cancer  

SciTech Connect (OSTI)

Metallothioneins (MTs) are highly conserved, small molecular weight, cysteine rich proteins. The major physiological functions of metallothioneins include homeostasis of essential metals Zn and Cu and protection against cytotoxicity of heavy metals. The aim of this study was to determine whether there is an association between the ? 5 A/G single nucleotide polymorphism (SNP; rs28366003) in core promoter region and expression of metallothionein 2A (MT2A) gene and metal concentration in prostate cancer tissues. MT2A polymorphism was determined by the polymerase chain reaction–restriction fragment length polymorphism technique (PCR–RFLP) using 412 prostate cancer tissue samples. MT2A gene expression analysis was performed by real-time RT-PCR method. A significant association between rs28366003 genotype and MT2A expression level was found. The average mRNA level was found to be lower among minor allele carriers (the risk allele) than average expression among homozygotes for the major allele. Metal levels were analyzed by flamed atomic absorption spectrometer system. Highly statistically significant associations were detected between the SNP and Cd, Zn, Cu and Pb levels. The results of Spearman's rank correlation showed that the expressions of MT2A and Cu, Pb and Ni concentrations were negatively correlated. On the basis of the results obtained in this study, we suggest that SNP polymorphism may affect the MT2A gene expression in prostate and this is associated with some metal accumulation. - Highlights: • MT2A gene expression and metal content in prostate cancer tissues • Association between SNP (rs28366003) and expression of MT2A • Significant associations between the SNP and Cd, Zn, Cu and Pb levels • Negative correlation between MT2A gene expression and Cu, Pb and Ni levels.

Krze?lak, Anna; Forma, Ewa [Department of Cytobiochemistry, University of ?ód?, Pomorska 141/143, 90-236 ?ód? (Poland); Chwatko, Gra?yna [Department of Environmental Chemistry, University of ?ód?, Pomorska 163, 90-236 ?ód? (Poland); Jó?wiak, Pawe?; Szymczyk, Agnieszka [Department of Cytobiochemistry, University of ?ód?, Pomorska 141/143, 90-236 ?ód? (Poland); Wilkosz, Jacek; Ró?a?ski, Waldemar [2nd Department of Urology, Medical University of ?ód?, Pabianicka 62, 93-513 ?ód? (Poland); Bry?, Magdalena, E-mail: zreg@biol.uni.lodz.pl [Department of Cytobiochemistry, University of ?ód?, Pomorska 141/143, 90-236 ?ód? (Poland)

2013-05-01T23:59:59.000Z

493

Differential transcriptional regulation of IL-8 expression by human airway epithelial cells exposed to diesel exhaust particles  

SciTech Connect (OSTI)

Exposure to diesel exhaust particles (DEP) induces inflammatory signaling characterized by MAP kinase-mediated activation of NFkB and AP-1 in vitro and in bronchial biopsies obtained from human subjects exposed to DEP. NFkB and AP-1 activation results in the upregulation of genes involved in promoting inflammation in airway epithelial cells, a principal target of inhaled DEP. IL-8 is a proinflammatory chemokine expressed by the airway epithelium in response to environmental pollutants. The mechanism by which DEP exposure induces IL-8 expression is not well understood. In the current study, we sought to determine whether DEP with varying organic content induces IL-8 expression in lung epithelial cells, as well as, to develop a method to rapidly evaluate the upstream mechanism(s) by which DEP induces IL-8 expression. Exposure to DEP with varying organic content differentially induced IL-8 expression and IL-8 promoter activity human airway epithelial cells. Mutational analysis of the IL-8 promoter was also performed using recombinant human cell lines expressing reporters linked to the mutated promoters. Treatment with a low organic-containing DEP stimulated IL-8 expression by a mechanism that is predominantly NFkB-dependent. In contrast, exposure to high organic-containing DEP induced IL-8 expression independently of NFkB through a mechanism that requires AP-1 activity. Our study reveals that exposure to DEP of varying organic content induces proinflammatory gene expression through multiple specific mechanisms in human airway epithelial cells. The approaches used in the present study demonstrate the utility of a promoter-reporter assay ensemble for identifying transcriptional pathways activated by pollutant exposure.

Tal, Tamara L. [Curriculum in Toxicology, University of North Carolina, Chapel Hill (United States); Simmons, Steven O. [Integrated Systems Toxicology, National Health and Environmental Effects Research Laboratory, U.S. EPA (United States); Silbajoris, Robert; Dailey, Lisa [Environmental and Public Health, National Health and Environmental Effects Research Laboratory, U.S. EPA (United States); Cho, Seung-Hyun [Air Pollution Prevention Control Division, National Risk Management Research Laboratory, U.S. EPA (United States); Research Participation Program, Oak Ridge Institute for Science and Education, Oak Ridge (United States); Ramabhadran, Ram [Curriculum in Toxicology, University of North Carolina, Chapel Hill (United States); Integrated Systems Toxicology, National Health and Environmental Effects Research Laboratory, U.S. EPA (United States); Linak, William [Air Pollution Prevention Control Division, National Risk Management Research Laboratory, U.S. EPA (United States); Reed, William; Bromberg, Philip A. [Center for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill (United States); Samet, James M., E-mail: samet.james@epa.go [Curriculum in Toxicology, University of North Carolina, Chapel Hill (United States); Environmental and Public Health, National Health and Environmental Effects Research Laboratory, U.S. EPA (United States)

2010-02-15T23:59:59.000Z

494

Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells  

SciTech Connect (OSTI)

Vascular smooth muscle cell (VSMC) proliferation remains a major cause of veno-arterial graft failure. We hypothesised that exposure of venous SMCs to arterial pressure would increase KLF5 expression and that of cell cycle genes. Porcine jugular veins were perfused at arterial or venous pressure in the absence of growth factors. The KLF5, c-myc, cyclin-D and cyclin-E expression were elevated within 24 h of perfusion at arterial pressure but not at venous pressure. Arterial pressure also reduced the decline in SM-myosin heavy chain expression. These data suggest a role for KLF5 in initiating venous SMCs proliferation in response to arterial pressure.

Amirak, Emre [Section of Molecular Medicine, National Heart and Lung Institute, Imperial College London, Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ (United Kingdom)] [Section of Molecular Medicine, National Heart and Lung Institute, Imperial College London, Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ (United Kingdom); Zakkar, Mustafa; Evans, Paul C. [Cardiovascular Sciences, Bywaters Center for Vascular Inflammation, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London W12 ONN (United Kingdom)] [Cardiovascular Sciences, Bywaters Center for Vascular Inflammation, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London W12 ONN (United Kingdom); Kemp, Paul R., E-mail: p.kemp@imperial.ac.uk [Section of Molecular Medicine, National Heart and Lung Institute, Imperial College London, Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ (United Kingdom)

2010-01-01T23:59:59.000Z

495

#2340 -$10.00 US Received August 25, 1997; Revised November 5, 1997 (C) 1997 OSA 10 November 1997 / Vol. 1, No. 10 / OPTICS EXPRESS 293  

E-Print Network [OSTI]

/ Vol. 1, No. 10 / OPTICS EXPRESS 293 #12;#2340 - $10.00 US Received August 25, 1997; Revised November 5, 1997 (C) 1997 OSA 10 November 1997 / Vol. 1, No. 10 / OPTICS EXPRESS 294 #12;#2340 - $10.00 US Received August 25, 1997; Revised November 5, 1997 (C) 1997 OSA 10 November 1997 / Vol. 1, No. 10 / OPTICS EXPRESS

Walsworth, Ronald L.

496

Two Residues in the T-loop of GlnK Determine NifL-dependent Nitrogen Control of nif Gene Expression*  

E-Print Network [OSTI]

Two Residues in the T-loop of GlnK Determine NifL-dependent Nitrogen Control of nif Gene Expression NifL-mediated inhibition of NifA activity in response to the nitrogen status, and GlnB, when expressed heterologous system, in which K. pneumoniae nifLA is expressed in E. coli, to investigate the impor- tance

Merrick, Mike

497

Using the Cre-loxP system to randomize target gene expression states and generate diverse phenotypes  

E-Print Network [OSTI]

Modifying the expression of multiple genes enables both deeper understanding of their function and the engineering of complex multigenic cellular phenotypes. However, deletion or overexpression of multiple genes is typically ...

Niesner, Bradley (Bradley Joseph)

2013-01-01T23:59:59.000Z

498

Expression of the bovine DNA (cytosine 5) methyltransferase family during preimplantation development and aberrations induced by somatic cell nuclear transfer  

E-Print Network [OSTI]

is that the genomic hypermethylation and improper epigenetic reprogramming reported in studies of bovine nuclear transfer, are in large part due to abnormal expression and regulation of the DNA methyltransferase proteins. Bovine Dnmt mRNAs display strong sequence...

Golding, Michael Cameron

2005-02-17T23:59:59.000Z

499

Functional expression of P-glycoprotein in primary cultures of human cytotrophoblasts and BeWo cells  

E-Print Network [OSTI]

The objective of this study was to investigate the functional expression of the efflux transporter, P-glycoprotein (P-gp), in primary cultures of human cytotrophoblasts and BeWo cell monolayers. Uptake studies with primary ...

Utoguchi, Naoki; Chandorkar, Gurudatt A.; Avery, Michael; Audus, Kenneth L.

2000-01-01T23:59:59.000Z

500

Dual expression of hTERT and VEGF prolongs life span and enhances angiogenic ability of aged BMSCs  

SciTech Connect (OSTI)

Highlights: •Expression of hTERT and VEGF changed the lifespan and morphology of hBMSCs. •The expression of VEGF and hTRET promoted angiogenesis in vitro and in vivo. •The expression of VEGF and hTRET in hBMSCs had few effects on tumorigenicity. -- Abstract: Previous studies have confirmed the therapeutic effects of bone marrow stromal cells (BMSCs) transplantation on cerebral ischemia. However, the proliferative, differentiative, and homing capacity of BMSC from the elderly are significantly reduced, especially after several passages expansion in vitro. In this study, by introducing lentivirus-mediated hTERT and VEGF genes to modify human BMSCs from aged donors, we observed extended lifespan, promoted angiogenic capacity while less enhanced tumorigenicity of the genetically engineering BMSCs. These results therefore suggest that the modification of aged BMSCs by dual expression of hTERT and VEGF may be used for autologous cell replacement for ischemic cerebrovascular disease in elderly patients.

Tang, Hao [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China) [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China); Department of Neurosurgery, Affiliated Bayi Brain Hospital, The Military General Hospital of Beijing PLA, Beijing (China); Xiang, Yongsheng [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China) [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China); Department of Neurosurgery, First Affiliated Hospital of Jinan University, Guangzhou (China); Jiang, Xiaodan; Ke, Yiquan; Xiao, Zongyu; Guo, Yang; Wang, Qiujing; Du, Mouxuan; Qin, Linsha; Zou, Yuxi; Cai, Yingqian [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China)] [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China); Chen, Zhenzhou, E-mail: czz1020@163.com [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China)] [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China); Xu, Ruxiang, E-mail: zjxuruxiang@163.com [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China) [Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou (China); Department of Neurosurgery, Affiliated Bayi Brain Hospital, The Military General Hospital of Beijing PLA, Beijing (China)

2013-11-01T23:59:59.000Z