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Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

National Institute on Aging HIV, AIDS, and  

E-Print Network [OSTI]

-term memory loss. You can now also test your blood at home. The "Home Access Express HIV-1 Test System, a close family friend she had known for a long time, was starting to stay overnight more and more often HIV and AIDS. You may have thought that these diseases weren't your problem and that only younger

Levin, Judith G.

2

Successful cognitive aging in persons living with HIV infection  

E-Print Network [OSTI]

medical evaluations. Successful cognitive aging (SCA) wasby a battery of well- validated cognitive tests andself-endorsed cognitive com- plaints. Thirty-two percent of

2011-01-01T23:59:59.000Z

3

Feeding the periphery : modeling early Bronze Age economies and the cultural landscape of the Faynan District, Southern Jordan  

E-Print Network [OSTI]

Archaeology and Early Metallurgy at Khirbet Hamra Ifdan andSabanne 1989 Copper Metallurgy, Trade and the Urbanization2002 Early Bronze Age Metallurgy: A Newly Discovered Copper

Muniz, Adolfo A.

2007-01-01T23:59:59.000Z

4

Improved age control on early Homo fossils from the upper Burgi Member at Koobi Fora, Kenya  

E-Print Network [OSTI]

Improved age control on early Homo fossils from the upper Burgi Member at Koobi Fora, Kenya in Areas 105 and 131 on the Karari Ridge in the eastern Turkana Basin (Kenya). We identify the base

Utrecht, Universiteit

5

Improved age control on early Homo fossils from the upper Burgi Member at Koobi Fora, Kenya  

E-Print Network [OSTI]

1 Improved age control on early Homo fossils from the upper Burgi Member at Koobi Fora, Kenya in Areas 105 and 131 on the Karari Ridge in the eastern Turkana Basin (Kenya). We identify the base

Paris-Sud XI, Université de

6

Tackling Dyslexia at an Early Age esearchers at HMS and Boston Children's  

E-Print Network [OSTI]

Tackling Dyslexia at an Early Age R esearchers at HMS and Boston Children's Hospital who have been studying dyslexia in children have identified differences in the brain activity of at-risk children that very young children at risk for dyslexia could take part in early intervention programs that may help

Corey, David P.

7

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of apobec  

SciTech Connect (OSTI)

The pattern of viral diversification in newly infected individuals provides information about the host environment and immune responses typically experienced by the newly transmitted virus. For example, sites that tend to evolve rapidly across multiple early-infection patients could be involved in enabling escape from common early immune responses, represent adaptation for rapid growth in a newly infected host, or reversion from less fit forms of the virus that were selected for immune escape in previous hosts. Here we investigated the diversification of HIV -I env coding sequences in 81 very early B SUbtype infections previously shown to have resulted from transmission or expansion of single viruses (n=78) or two closely related viruses (n=3). In these cases the sequence of the infecting virus can be estimated accurately, enabling inference of both the direction of substitutions as well as distinction between insertion and deletion events. By integrating information across multiple acutely infected hosts, we find evidence of adaptive evolution of HIV-1 envand identified a subset of codon sites that diversified more rapidly than can be explained by a model of neutral evolution. Of 24 such rapidly diversifying sites, 14 were either (i) clustered and embedded in CTL epitopes that were verified experimentally or predicted based on the individual's HLA or (ii) in a nucleotide context indicative of APOBEC mediated G-to-A substitutions, despite having excluded heavily hypermutated sequences prior to the analysis. In several cases, a rapidly evolving site was both embedded in an APOBEC motif and in a CTL epitope, suggesting that APOBEC may facilitate early immune escape. Ten rapidly diversifying sites could not be explained by CTL escape or APOBEC hypermutation, including the most frequently mutated site, in the fusion peptide of gp4l. We also examined the distribution, extent, and sequence context of insertions and deletions and provide evidence that the length variation seen in hypervariable loop regions of the envelope glycoprotein is a consequence of selection and not mutational hotspots. These results provide a detailed view of the process of diversification of HIV-1 following transmission.

Korber, Bette [Los Alamos National Laboratory; Bhattacharya, Tanmoy [Los Alamos National Laboratory; Giorgi, Elena [Los Alamos National Laboratory; Gaschen, B [Los Alamos National Laboratory; Daniels, M [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

8

Evidence for kill-butchery events of early Upper Paleolithic age at Kostenki, Russia  

E-Print Network [OSTI]

Evidence for kill-butchery events of early Upper Paleolithic age at Kostenki, Russia John F, Universitetskaya nab., 1, 199034 St. Petersburg, Russia c Institute of the History of Material Culture, Russian Academy of Sciences, Dvortsovaya nab., 18, 191186 St. Petersburg, Russia d Kostenki Museum-Preserve, ul

Holliday, Vance T.

9

Keynote Paper, Shah, Page 1/13 HEALTH MONITORING OF EARLY AGE CONCRETE  

E-Print Network [OSTI]

relationship to the actual concrete in the structure. This calls for nondestructive test methods that offer potential for the application of nondestructive testing of concrete under field conditions. The resultsKeynote Paper, Shah, Page 1/13 HEALTH MONITORING OF EARLY AGE CONCRETE Thomas Voigt, Zhihui Sun

10

Protein Structure Could Lead to Better Treatments for HIV, Early Aging |  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedlesAdvanced Photon Source The Superpower behind Iron

11

Early Jurassic shale chemostratigraphy and UPb ages from the Neuqun Basin (Argentina): Implications for the Toarcian Oceanic Anoxic Event  

E-Print Network [OSTI]

Early Jurassic shale chemostratigraphy and U­Pb ages from the Neuquén Basin (Argentina shale section in the Neuquén Basin, Argentina, are presented in order to better constrain the triggering. Chemostratigraphy from a 65 m thick shale-dominated marine section of Late Pliensbachian to Early Toarcian age shows

Svensen, Henrik

12

Prediction of early-age cracking of UHPC materials and structures : a thremo-chemo-mechanics approach  

E-Print Network [OSTI]

Ultra-High Performance Concrete [UHPC] has remarkable performance in mechanical properties, ductility, economical benefit, etc., but early-age cracking of UHPC can become an issue during the manufacturing process due to ...

Shim, JongMin, 1975-

2005-01-01T23:59:59.000Z

13

An early Miocene age for a high-temperature event in gneisses from Zabargad Island (Red Sea, Egypt): mantle diapirism?  

E-Print Network [OSTI]

An early Miocene age for a high-temperature event in gneisses from Zabargad Island (Red Sea, Egypt outcropping on Zabargad Island (Red Sea, Egypt). This island, though of limited size (& 4 km2 ), has an almost

Demouchy, Sylvie

14

Atomic structure of Cu-10. 9 at % Be alloys in the early stages of aging  

SciTech Connect (OSTI)

Diffuse x-ray scattering was employed to investigate the local atomic structure and static strains in a single crystal of a Cu-10.9 at. % Be alloy in the early stages of aging. In addition to these experiments, neutron elastic and inelastic scattering were obtained to investigate the phonon properties in the as-quenched state of this alloy. In the as-quenched state, there is a nearly regular array of small ellipsoidal Be clusters aligned along <100> directions (This produces the tweed contrast seen in TEM). The density of these clusters is 7.5 x 10/sup 26//m/sup 3/. The diffuse streaks seen in electron diffraction patterns are due largely to thermal diffuse scattering. Phonon-dispersion curves show no large differences from those of pure copper, except at (xi xi xi)/sub T/ zone boundary, where there is softening. This difference may be due to a Kohn anomaly. The elastic anisotropy of this alloy increases considerably with alloying, which probably leads to the plate-like GP zone morphology in subsequent aging treatments. The structure of the GP zones is a mixture of Be-rich single- and multi-layered zones. As aging proceeds, the zones grow in thickness.

Koo, Y.M.

1987-01-01T23:59:59.000Z

15

PLANETARY-SCALE STRONTIUM ISOTOPIC HETEROGENEITY AND THE AGE OF VOLATILE DEPLETION OF EARLY SOLAR SYSTEM MATERIALS  

SciTech Connect (OSTI)

Isotopic anomalies in planetary materials reflect both early solar nebular heterogeneity inherited from presolar stellar sources and processes that generated non-mass-dependent isotopic fractionations. The characterization of isotopic variations in heavy elements among early solar system materials yields important insight into the stellar environment and formation of the solar system, and about initial isotopic ratios relevant to long-term chronological applications. One such heavy element, strontium, is a central element in the geosciences due to wide application of the long-lived {sup 87}Rb-{sup 87}Sr radioactive as a chronometer. We show that the stable isotopes of Sr were heterogeneously distributed at both the mineral scale and the planetary scale in the early solar system, and also that the Sr isotopic heterogeneities correlate with mass-independent oxygen isotope variations, with only CI chondrites plotting outside of this correlation. The correlation implies that most solar system material formed by mixing of at least two isotopically distinct components: a CV-chondrite-like component and an O-chondrite-like component, and possibly a distinct CI-chondrite-like component. The heterogeneous distribution of Sr isotopes may indicate that variations in initial {sup 87}Sr/{sup 86}Sr of early solar system materials reflect isotopic heterogeneity instead of having chronological significance, as interpreted previously. For example, given the differences in {sup 84}Sr/{sup 86}Sr between calcium aluminum inclusions and eucrites ({epsilon}{sup 84}Sr > 2), the difference in age between these materials would be {approx}6 Ma shorter than previously interpreted, placing the Sr chronology in agreement with other long- and short-lived isotope systems, such as U-Pb and Mn-Cr.

Moynier, Frederic; Podosek, Frank A. [Department of Earth and Planetary Science and McDonnell Center for Space Sciences, Washington University, St. Louis, MO 63130 (United States); Day, James M. D. [Geosciences Research Division, Scripps Institution of Oceanography, La Jolla, CA 92093-0244 (United States); Okui, Wataru; Yokoyama, Tetsuya [Department of Earth and Planetary Sciences, Tokyo Institute of Technology, Tokyo 152-8551 (Japan); Bouvier, Audrey [Department of Earth Sciences, University of Minnesota, Minneapolis, MN 55455-0231 (United States); Walker, Richard J., E-mail: moynier@levee.wustl.edu, E-mail: fap@levee.wustl.edu, E-mail: jmdday@ucsd.edu, E-mail: rjwalker@umd.edu, E-mail: okui.w.aa@m.titech.ac.jp, E-mail: tetsuya.yoko@geo.titech.ac.jp, E-mail: abouvier@umn.edu [Department of Geology, University of Maryland, College Park, MD 20742 (United States)

2012-10-10T23:59:59.000Z

16

In-situ early-age hydration study of sulfobelite cements by synchrotron powder diffraction  

SciTech Connect (OSTI)

Eco-friendly belite calcium sulfoaluminate (BCSA) cement hydration behavior is not yet well understood. Here, we report an in-situ synchrotron X-ray powder diffraction study for the first hours of hydration of BCSA cements. Rietveld quantitative phase analysis has been used to establish the degree of reaction (?). The hydration of a mixture of ye'elimite and gypsum revealed that ettringite formation (? ? 70% at 50 h) is limited by ye'elimite dissolution. Two laboratory-prepared BCSA cements were also studied: non-active-BCSA and active-BCSA cements, with ?- and ??{sub H}-belite as main phases, respectively. Ye'elimite, in the non-active-BCSA system, dissolves at higher pace (? ? 25% at 1 h) than in the active-BCSA one (? ? 10% at 1 h), with differences in the crystallization of ettringite (? ? 30% and ? ? 5%, respectively). This behavior has strongly affected subsequent belite and ferrite reactivities, yielding stratlingite and other layered phases in non-active-BCSA. The dissolution and crystallization processes are reported and discussed in detail. -- Highlights: Belite calcium sulfoaluminate cements early hydration mechanism has been determined. Belite hydration strongly depends on availability of aluminum hydroxide. Orthorhombic yeelimite dissolved at a higher pace than cubic one. Yeelimite larger reaction degree yields stratlingite formation by belite reaction. Rietveld method quantified gypsum, anhydrite and bassanite dissolution rates.

lvarez-Pinazo, G.; Cuesta, A.; Garca-Mat, M.; Santacruz, I.; Losilla, E.R. [Departamento de Qumica Inorgnica, Universidad de Mlaga, Campus Teatinos S/N., 29071 Mlaga (Spain)] [Departamento de Qumica Inorgnica, Universidad de Mlaga, Campus Teatinos S/N., 29071 Mlaga (Spain); Sanflix, S.G. [Unidad Tcnica de Investigacin de Materiales, AIDICO, Avda. Benjamn Franklin, 17 Paterna, Valencia (Spain)] [Unidad Tcnica de Investigacin de Materiales, AIDICO, Avda. Benjamn Franklin, 17 Paterna, Valencia (Spain); Fauth, F. [CELLS-Alba synchrotron, Carretera BP 1413, Km. 3.3, E-08290 Cerdanyola, Barcelona (Spain)] [CELLS-Alba synchrotron, Carretera BP 1413, Km. 3.3, E-08290 Cerdanyola, Barcelona (Spain); Aranda, M.A.G. [Departamento de Qumica Inorgnica, Universidad de Mlaga, Campus Teatinos S/N., 29071 Mlaga (Spain) [Departamento de Qumica Inorgnica, Universidad de Mlaga, Campus Teatinos S/N., 29071 Mlaga (Spain); CELLS-Alba synchrotron, Carretera BP 1413, Km. 3.3, E-08290 Cerdanyola, Barcelona (Spain); De la Torre, A.G., E-mail: mgd@uma.es [Departamento de Qumica Inorgnica, Universidad de Mlaga, Campus Teatinos S/N., 29071 Mlaga (Spain)

2014-02-15T23:59:59.000Z

17

Stellar age versus mass of early-type galaxies in the Virgo Cluster  

E-Print Network [OSTI]

The flux excess of elliptical galaxies in the far-ultraviolet can be reproduced by population synthesis models when accounting for the population of old hot helium-burning subdwarf stars. This has been achieved by Han and coworkers through a quantitative model of binary stellar evolution. Here, we compare the resulting evolutionary population synthesis model to the GALEX far-near ultraviolet colors (FUV-NUV) of Virgo cluster early-type galaxies that were published by Boselli and coworkers. FUV-NUV is reddest at about the dividing luminosity of dwarf and giant galaxies, and becomes increasingly blue for both brighter and fainter luminosities. This behavior can be easily explained by the binary model with a continuous sequence of longer duration and later truncation of star formation at lower galaxy masses. Thus, in contrast to previous conclusions, the GALEX data do not require a dichotomy between the stellar population properties of dwarfs and giants. Their apparently opposite behavior in FUV-NUV occurs naturally when the formation of hot subdwarfs through binary evolution is taken into account.

Thorsten Lisker; Zhanwen Han

2008-03-17T23:59:59.000Z

18

The Ages of Early-Type Stars: Str\\"omgren Photometric Methods Calibrated, Validated, Tested, and Applied to Hosts and Prospective Hosts of Directly Imaged Exoplanets  

E-Print Network [OSTI]

Age determination is undertaken for nearby early-type (BAF) stars, which constitute attractive targets for high-contrast debris disk and planet imaging surveys. Our analysis sequence consists of: acquisition of uvby{\\beta} photometry from catalogs, correction for the effects of extinction, interpolation of the photometry onto model atmosphere grids from which atmospheric parameters are determined, and finally, comparison to the theoretical isochrones from pre-main sequence through post-main sequence stellar evolution models, accounting for the effects of stellar rotation. We calibrate and validate our methods at the atmospheric parameter stage by comparing our results to fundamentally determined Teff and log g values. We validate and test our methods at the evolutionary model stage by comparing our results on ages to the accepted ages of several benchmark open clusters (IC 2602, {\\alpha} Persei, Pleiades, Hyades). Finally, we apply our methods to estimate stellar ages for 3493 field stars, including several w...

David, Trevor J

2015-01-01T23:59:59.000Z

19

Secondary state formation during the early iron age on the island of Sri Lanka : the evolution of a periphery  

E-Print Network [OSTI]

socio-political and economic process during early historica major socio- economic and political process that isthe socio-economic and political process in the hinterlands.

Karunaratne, Priyantha Padmalal

2010-01-01T23:59:59.000Z

20

Musicians' Enhanced Neural Differentiation of Speech Sounds Arises Early in Life: Developmental Evidence from Ages 3 to 30  

E-Print Network [OSTI]

Musicians' Enhanced Neural Differentiation of Speech Sounds Arises Early in Life: Developmental; this training may generalize to speech processing given that adult musicians have enhanced neural-Muniz et al. 2012). We recently reported enhanced subcortical distinction of similar speech sounds (e

Kraus, Nina

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

The Chachil Limestone (Pliensbachianeearliest Toarcian) Neuqun Basin, Argentina: UePb age calibration and its significance on the Early Jurassic  

E-Print Network [OSTI]

The Chachil Limestone (Pliensbachianeearliest Toarcian) Neuquén Basin, Argentina: UePb age Geológico Minero Argentino and CONICET, Av. Julio A. Roca 651, 1322 Buenos Aires, Argentina b Physics Geológicas, Universidad Nacional de la Plata, Calle 1 - # 644, 1900 La Plata, Argentina e Volcanic Basin

Mazzini, Adriano

22

aging aircraft nondestructive: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

at Early Ages An Experimental and Numerical Analysis by Dr for Nondestructive Testing of Cement-Based Materials at Early Ages - An Experi- mental and Numerical Analysis...

23

Design and expression of a short peptide as an HIV detection probe  

SciTech Connect (OSTI)

Highlights: We designed a short fusion peptide (FP-50) for in vivo expression. This peptide is a very promising component for detection of gp120 protein. The detectable level is about 20200 times lower than previously published methods. It is a novel probe to detect HIV-1 gp120 during early stages of HIV infection. -- Abstract: To explore a low-cost novel probe for HIV detection, we designed and prepared a 50-amino acid-length short fusion peptide (FP-50) via Escherichia coli in vivo expression. It was employed as a novel probe to detect HIV-1 gp120 protein. The detectable level of gp120 protein using the FP-50 peptide was approximately 20200 times lower than previously published methods that used a pair of monoclonal antibodies. Thus, this short peptide is a very promising component for detection of gp120 protein during early stages of HIV infection.

Lines, Jamie A.; Yu, Zhiqiang; Dedkova, Larisa M.; Chen, Shengxi, E-mail: shengxi.chen.1@asu.edu

2014-01-03T23:59:59.000Z

24

Please cite this article in press as: DiNapoli, V.A. et al., Early disruptions of the bloodbrain barrier may contribute to exacerbated neuronal damage and prolonged functional recovery following stroke in aged rats, Neurobiol Aging (2007),  

E-Print Network [OSTI]

­brain barrier may contribute to exacerbated neuronal damage and prolonged functional recovery following stroke may contribute to exacerbated neuronal damage and prolonged functional recovery following stroke the effects of age on stroke progression and outcome in order to explore the association between blood

25

The Evolution of the M_BH-sigma relation Inferred from the Age Distribution of Local Early-Type Galaxies and AGN Evolution  

E-Print Network [OSTI]

We utilize the local velocity dispersion function (VDF) of spheroids, together with their inferred age--distributions, to predict the VDF at higher redshifts (01.3 excluded at the 99% confidence level. A direct match between the characteristic BH mass in the VDF--based and quasar LF--based BH mass functions also yields a mean Eddington ratio of lambda ~ 0.5-1 that is roughly constant within 00.23 for alpha>1.5. abridged

Shankar, Francesco; Haiman, Zoltan

2008-01-01T23:59:59.000Z

26

Early Brain Response to Low-Dose Radiation Exposure Involves Molecular Networks and Pathways Associated with Cognitive Functions, Advanced Aging and Alzheimer's Disease  

SciTech Connect (OSTI)

Understanding the cognitive and behavioral consequences of brain exposures to low-dose ionizing radiation has broad relevance for health risks from medical radiation diagnostic procedures, radiotherapy, environmental nuclear contamination, as well as earth orbit and space missions. Analyses of transcriptome profiles of murine brain tissue after whole-body radiation showed that low-dose exposures (10 cGy) induced genes not affected by high dose (2 Gy), and low-dose genes were associated with unique pathways and functions. The low-dose response had two major components: pathways that are consistently seen across tissues, and pathways that were brain tissue specific. Low-dose genes clustered into a saturated network (p < 10{sup -53}) containing mostly down-regulated genes involving ion channels, long-term potentiation and depression, vascular damage, etc. We identified 9 neural signaling pathways that showed a high degree of concordance in their transcriptional response in mouse brain tissue after low-dose radiation, in the aging human brain (unirradiated), and in brain tissue from patients with Alzheimer's disease. Mice exposed to high-dose radiation did not show these effects and associations. Our findings indicate that the molecular response of the mouse brain within a few hours after low-dose irradiation involves the down-regulation of neural pathways associated with cognitive dysfunctions that are also down regulated in normal human aging and Alzheimer's disease.

Lowe, Xiu R; Bhattacharya, Sanchita; Marchetti, Francesco; Wyrobek, Andrew J.

2008-06-06T23:59:59.000Z

27

A new challenge? HIV/AIDS as a development issue  

E-Print Network [OSTI]

children have been infected with the HIV virus · 15 million children under age 18 have lost one or both parents to AIDS. More than 12 million are in sub-Saharan Africa · The chances of orphans going to school parents or go and make money · erosion of number of teachers #12;(b) health sector · new drugs are very

Glasgow, University of

28

american children ages: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

july 2004 Age-Specific Demography in Plantago: Uncovering Roach,. Deborah 17 Tackling Dyslexia at an Early Age esearchers at HMS and Boston Children's Biology and Medicine Websites...

29

Aging gauge  

DOE Patents [OSTI]

An aging gauge comprising a container having a fixed or a variable sized t opening with a cap which can be opened to control the sublimation rate of a thermally sublimational material contained within the container. In use, the aging gauge is stored with an item to determine total heat the item is subjected to and also the maximum temperature to which the item has been exposed. The aging gauge container contains a thermally sublimational material such as naphthalene or similar material which has a low sublimation rate over the temperature range from about 70.degree. F. to about 160.degree. F. The aging products determined by analyses of a like item aged along with the aging gauge for which the sublimation amount is determined is employed to establish a calibration curve for future aging evaluation. The aging gauge is provided with a means for determining the maximum temperature exposure (i.e., a thermally indicating material which gives an irreversible color change, Thermocolor pigment). Because of the relationship of doubling reaction rates for increases of 10.degree. C., equivalency of item used in accelerated aging evaluation can be obtained by referring to a calibration curve depicting storage temperature on the abscissa scale and multiplier on the ordinate scale.

Betts, Robert E. (Huntsville, AL); Crawford, John F. (Huntsville, AL)

1989-01-01T23:59:59.000Z

30

Molecular evidence of HIV-1 transmission in a criminal case  

E-Print Network [OSTI]

to characterize HIV-1-positive samples identif, Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109; and **Section of Integrative, the patient, and a local population sample of HIV-1-positive individuals showed the victim's HIV-1 sequences

Hillis, David

31

Relative Ages of Globular Clusters  

E-Print Network [OSTI]

Ages of extragalactic globular clusters can provide valuable insights into the formation and evolution of galaxies. In this contribution the photometric methods of age dating old globular cluster systems are summarised. The spectroscopic approach is reviewed with an emphasis of the right choice of age diagnostics. We present a new method of quantifying the relatively best age-sensitive spectroscopic index given the quality of a data set and a certain theoretical stellar synthesis model. The relatively best diagnostic plot is constructed from the set of Lick indices and used to age date globular clusters in several early-type galaxies which are part of a large spectroscopic survey of extragalactic globular cluster systems. We find that, independently of host galaxy, metal-poor ([Fe/H] 8 Gyr) and coeval. Metal-rich clusters show a wide range of ages from ~15 down to a few Gyr.

Thomas H. Puzia

2002-10-18T23:59:59.000Z

32

Cognitive Neuropsychology of HIV-Associated Neurocognitive Disorders  

E-Print Network [OSTI]

of HIV-associated cognitive impairment. The ClinicalRourke, B. P. (2003). Cognitive complaints, depression,predicts subjective cognitive complaints in HIV infection.

Woods, Steven Paul; Moore, David J.; Weber, Erica; Grant, Igor

2009-01-01T23:59:59.000Z

33

antiretroviral experienced hiv: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

virus (HIV) infectionpostpartum Vietnamese women with HIV experienced through their family and community relationships was a painful, daily reminder of their infection...

34

HIV virus spread and evolution studied through computer modeling  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HIV and evolution studied through computer modeling HIV virus spread and evolution studied through computer modeling This approach distinguishes between susceptible and infected...

35

age children group: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

surface area, and thickness measures were obtained. Anxiety symptoms were 22 Tackling Dyslexia at an Early Age esearchers at HMS and Boston Children's Biology and Medicine Websites...

36

aged children hbsc: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

surface area, and thickness measures were obtained. Anxiety symptoms were 13 Tackling Dyslexia at an Early Age esearchers at HMS and Boston Children's Biology and Medicine Websites...

37

age children preliminary: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

surface area, and thickness measures were obtained. Anxiety symptoms were 17 Tackling Dyslexia at an Early Age esearchers at HMS and Boston Children's Biology and Medicine Websites...

38

Earth: The Early Years We discuss ...  

E-Print Network [OSTI]

Earth: The Early Years We discuss ... · What happened to the Earth during the first few billion)? · What is the relationship to (early) life? #12;Age of Earth James Ussher (17th C) biblical account: 6: 20-40 m.y. (million years!) Charles Darwin evolution >300 m.y. Lord Kelvin (1880's) cooling Earth: 50

39

E-Print Network 3.0 - anti-hiv drug regimens Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

body's natural anti-HIV immune... , there are no therapeutic HIV vaccines approved by the Food and DrugAdministration (FDA). However, therapeutic HIV vaccines... response, people...

40

HIV-1 transmission linkage in an HIV-1 prevention clinical trial  

SciTech Connect (OSTI)

HIV-1 sequencing has been used extensively in epidemiologic and forensic studies to investigate patterns of HIV-1 transmission. However, the criteria for establishing genetic linkage between HIV-1 strains in HIV-1 prevention trials have not been formalized. The Partners in Prevention HSV/HIV Transmission Study (ClinicaITrials.gov NCT00194519) enrolled 3408 HIV-1 serodiscordant heterosexual African couples to determine the efficacy of genital herpes suppression with acyclovir in reducing HIV-1 transmission. The trial analysis required laboratory confirmation of HIV-1 linkage between enrolled partners in couples in which seroconversion occurred. Here we describe the process and results from HIV-1 sequencing studies used to perform transmission linkage determination in this clinical trial. Consensus Sanger sequencing of env (C2-V3-C3) and gag (p17-p24) genes was performed on plasma HIV-1 RNA from both partners within 3 months of seroconversion; env single molecule or pyrosequencing was also performed in some cases. For linkage, we required monophyletic clustering between HIV-1 sequences in the transmitting and seroconverting partners, and developed a Bayesian algorithm using genetic distances to evaluate the posterior probability of linkage of participants sequences. Adjudicators classified transmissions as linked, unlinked, or indeterminate. Among 151 seroconversion events, we found 108 (71.5%) linked, 40 (26.5%) unlinked, and 3 (2.0%) to have indeterminate transmissions. Nine (8.3%) were linked by consensus gag sequencing only and 8 (7.4%) required deep sequencing of env. In this first use of HIV-1 sequencing to establish endpoints in a large clinical trial, more than one-fourth of transmissions were unlinked to the enrolled partner, illustrating the relevance of these methods in the design of future HIV-1 prevention trials in serodiscordant couples. A hierarchy of sequencing techniques, analysis methods, and expert adjudication contributed to the linkage determination process.

Leitner, Thomas [Los Alamos National Laboratory; Campbell, Mary S [UNIV OF WASHINGTON; Mullins, James I [UNIV OF WASHINGTON; Hughes, James P [UNIV OF WASHINGTON; Wong, Kim G [UNIV OF WASHINGTON; Raugi, Dana N [UNIV OF WASHINGTON; Scrensen, Stefanie [UNIV OF WASHINGTON

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Design Evolution Study - Aging Options  

SciTech Connect (OSTI)

The purpose of this study is to identify options and issues for aging commercial spent nuclear fuel received for disposal at the Yucca Mountain Mined Geologic Repository. Some early shipments of commercial spent nuclear fuel to the repository may be received with high-heat-output (younger) fuel assemblies that will need to be managed to meet thermal goals for emplacement. The capability to age as much as 40,000 metric tons of heavy metal of commercial spent nuclear he1 would provide more flexibility in the design to manage this younger fuel and to decouple waste receipt and waste emplacement. The following potential aging location options are evaluated: (1) Surface aging at four locations near the North Portal; (2) Subsurface aging in the permanent emplacement drifts; and (3) Subsurface aging in a new subsurface area. The following aging container options are evaluated: (1) Complete Waste Package; (2) Stainless Steel inner liner of the waste package; (3) Dual Purpose Canisters; (4) Multi-Purpose Canisters; and (5) New disposable canister for uncanistered commercial spent nuclear fuel. Each option is compared to a ''Base Case,'' which is the expected normal waste packaging process without aging. A Value Engineering approach is used to score each option against nine technical criteria and rank the options. Open issues with each of the options and suggested future actions are also presented. Costs for aging containers and aging locations are evaluated separately. Capital costs are developed for direct costs and distributable field costs. To the extent practical, unit costs are presented. Indirect costs, operating costs, and total system life cycle costs will be evaluated outside of this study. Three recommendations for aging commercial spent nuclear fuel--subsurface, surface, and combined surface and subsurface are presented for further review in the overall design re-evaluation effort. Options that were evaluated but not recommended are: subsurface aging in a new subsurface area (high cost); surface aging in the complete waste package (risk to the waste package and impact on the Waste Handling Facility); and aging in the stainless steel liner (impact on the waste package design and new high risk operations added to the waste packaging process). The selection of a design basis for aging will be made in conjunction with the other design re-evaluation studies.

P. McDaniel

2002-04-05T23:59:59.000Z

42

Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins  

DOE Patents [OSTI]

The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Korber, Bette T. (Los Alamos, NM); Perkins, Simon (Los Alamos, NM); Bhattacharya, Tanmoy (Los Alamos, NM); Fischer, William M. (Los Alamos, NM); Theiler, James (Los Alamos, NM); Letvin, Norman (Boston, MA); Haynes, Barton F. (Durham, NC); Hahn, Beatrice H. (Birmingham, AL); Yusim, Karina (Los Alamos, NM); Kuiken, Carla (Los Alamos, NM)

2012-02-21T23:59:59.000Z

43

HIV-Encephalitis: Mechanisms for CXCL10 Induction in Astrocytes  

E-Print Network [OSTI]

With the prevalence of HIV-associated neurocognitive disorders (HAND) increasing, understanding the mechanisms by which HIV induces neuro-inflammation and subsequent neuronal damage is of paramount importance. We hypothesized ...

Williams, Rachel

2009-06-23T23:59:59.000Z

44

adapted hiv prevention: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

- sexual, blood borne and mother to child. However, fewer than one in five people at high risk for HIV have access Bushman, Frederic 2 PROVEN HIV PREVENTION METHODS We...

45

adapting hiv prevention: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

- sexual, blood borne and mother to child. However, fewer than one in five people at high risk for HIV have access Bushman, Frederic 2 PROVEN HIV PREVENTION METHODS We...

46

HIV genetic research to be discussed at Bradbury Science Museum...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

to be discussed Feb. 12 HIV genetic research to be discussed at Bradbury Science Museum lecture Feb. 12 Tanmoy Bhattacharya will talk about the Lab's research in HIV genetics...

47

Using the social ecological model to understand the contextual factors associated with HIV risk in commercial sex workers at high risk for contracting HIV  

E-Print Network [OSTI]

and the Perceived Risk of Contracting HIV in a Drug Usingsex workers at high risk for contracting HIV A dissertationsex workers at high risk for contracting HIV by Sandra Erika

Larios, Sandra Erika

2008-01-01T23:59:59.000Z

48

Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral therapy  

E-Print Network [OSTI]

Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral-time PCR assay in multiple samples per patient with a median (interquartile range) follow-up of 76 (45­102) weeks. Results: The median (range) baseline HIV-1 DNA load was 297 (, 10 to 3468) copies per 1 3 106

49

Evolving T-cell vaccine strategies for HIV, the virus with a thousand faces  

SciTech Connect (OSTI)

HIV's rapid global spread and the human suffering it has left in its wake have made AIDS a global heath priority for the 25 years since its discovery. Yet its capacity to rapidly evolve has made combating this virus a tremendous challenge. The obstacles to creating an effective HIV vaccine are formidable, but there are advances in the field on many fronts, in terms of novel vectors, adjuvants, and antigen design strategies. SIV live attenuated vaccine models are able to confer protection against heterologous challenge, and this continues to provide opportunities to explore the biological underpinnings of a protective effect (9). More indirect, but equally important, is new understanding regarding the biology of acute infection (43), the role of immune response in long-term non-progression (6,62, 81), and defining characteristics of broadly neutralizing antibodies (4). In this review we will focus on summarizing strategies directed towards a single issue, that of contending with HIV variation in terms of designing aT-cell vaccine. The strategies that prove most effective in this area can ultimately be combined with the best strategies under development in other areas, with the hope of ultimately converging on a viable vaccine candidate. Only two large HIV vaccine efficacy trials have been completed and both have failed to prevent infection or confer a benefit to infected individual (23,34), but there is ample reason to continue our efforts. A historic breakthrough came in 1996, when it was realized that although the virus could escape from a single antiretroviral (ARV) therapy, it could be thwarted by a combination of medications that simultaneously targeted different parts of the virus (HAART) (38). This revelation came after 15 years of research, thought, and clinical testing; to enable that vital progress the research and clinical communities had to first define and understand, then develop a strategy to counter, the remarkable evolutionary potential of the virus. HAART, for the first time, provided an effective treatment to help those with living with HIV stay healthy. Nonetheless, the treatment has limitations. People with HIV face a lifetime of expensive daily multi-drug regimens, often with side effects; drug resistance at the individual and population level are issues (56); and universal access, despite substantial progress, is a dream not yet realized for many of the millions of the world's poor who are living with HIV (68). These issues, combined with the growing numbers of people infected globally and impact of HIV on society, make the development of an HIV vaccine or a prophylactic prevention strategy a crucial if elusive goal. In some ways, the history of HIV vaccine deVelopment has paralleled the early stages of designing effective therapy. We had to test the simple strategies first, but meanwhile the story of the impact of diversity from an immunological perspective is still unfolding, and novel ideas countermeasures are being explored.

Korber, Bette [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

50

Quantifying factors determining the rate of CTL escape and reversion during acute and chronic phases of HIV infection  

SciTech Connect (OSTI)

Human immunodeficiency virus (HIV) often evades cytotoxic T cell (CTL) responses by generating variants that are not recognized by CTLs. However, the importance and quantitative details of CTL escape in humans are poorly understood. In part, this is because most studies looking at escape of HIV from CTL responses are cross-sectional and are limited to early or chronic phases of the infection. We use a novel technique of single genome amplification (SGA) to identify longitudinal changes in the transmitted/founder virus from the establishment of infection to the viral set point at 1 year after the infection. We find that HIV escapes from virus-specific CTL responses as early as 30-50 days since the infection, and the rates of viral escapes during acute phase of the infection are much higher than was estimated in previous studies. However, even though with time virus acquires additional escape mutations, these late mutations accumulate at a slower rate. A poor correlation between the rate of CTL escape in a particular epitope and the magnitude of the epitope-specific CTL response suggests that the lower rate of late escapes is unlikely due to a low efficacy of the HIV-specific CTL responses in the chronic phase of the infection. Instead, our results suggest that late and slow escapes are likely to arise because of high fitness cost to the viral replication associated with such CTL escapes. Targeting epitopes in which virus escapes slowly or does not escape at all by CTL responses may, therefore, be a promising direction for the development of T cell based HIV vaccines.

Ganusov, Vitaly V [Los Alamos National Laboratory; Korber, Bette M [Los Alamos National Laboratory; Perelson, Alan S [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

51

EARLY-AGE CRACKING REVIEW: MECHANISMS, MATERIAL PROPERTIES,  

E-Print Network [OSTI]

Nuclear Solutions Cooperative Research Agreement (CRADA) CR-08-001. Reference herein to any specific

Bentz, Dale P.

52

Early age delamination in concrete pavements made with gravel aggregates  

E-Print Network [OSTI]

of delamination in CRC paving. Three continuous days from November 16 th to 18 th were spent for paving of total ten sections. Field data has been collected through various techniques available to TTI, Texas Department of Transportation (TxDOT), University...

Liu, Juanyu

2009-06-02T23:59:59.000Z

53

Early usage of DO in children with and without Specific Language Impairment  

E-Print Network [OSTI]

This study examined the early uses of DO in the spontaneous language samples of 89 children, 37 with Specific Language Impairment, age 5;0-5;6, 37 age-equivalent control children, and 15 language-equivalent control children, ...

Blossom, Megan Stratton

2009-09-15T23:59:59.000Z

54

E-Print Network 3.0 - age management intervention Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Diploma in Specialist Teaching Summary: in early intervention range in age from birth to 5 years, and have special learning, development... Postgraduate Diploma in...

55

E-Print Network 3.0 - aged concrete structures Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

risk of premature corrosion deterioration in concrete structures exposed to aggressive salt- laden... is slightly lower at early ages than those of control concretes but exceeds...

56

E-Print Network 3.0 - ao hiv em Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Ex Vivo-Expanded Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Infusion in HIV-Infected Patients Summary: , Edwards lack of disease in HIV-1-infected...

57

Whither India? Ten Lessons Learned from the HIV Epidemic in Africa  

E-Print Network [OSTI]

i31-9 Whither India? Lessons learned from the HIV epidemic139. Whither India? Lessons learned from the HIV epidemic in81. Whither India? Lessons learned from the HIV epidemic in

Potts, Malcolm; Walsh, Julia

2002-01-01T23:59:59.000Z

58

Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry  

E-Print Network [OSTI]

The analysis of HIV-1 envelope carbohydrates is critical to understanding their roles in HIV-1 transmission as well as in binding of envelope to HIV-1 antibodies. However, direct analysis of protein glycosylation by ...

Go, Eden P.; Hewawasam, Geetha; Lio, Hua-Xin; Chen, Haiyan; Ping, Li-Hua; Anderson, Jeffrey A.; Hua, David C.; Haynes, Barton F.; Desaire, Heather

2011-08-01T23:59:59.000Z

59

E-Print Network 3.0 - asia hiv observational Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

... Source: Ecole Polytechnique, Centre de mathmatiques Collection: Mathematics 3 Political Declaration on HIV and AIDS Intensifying Our Efforts to Eliminate HIV and AIDS...

60

Willingness to treat HIV-positive patients at different stages of medical education and experience.  

E-Print Network [OSTI]

patients and willingness to treat HIV-infected patients. Jprofessions students to treat patients with AIDS. Acad Medstu- dents' willingness to treat HIV-infected patients. Acad

Radecki, S; Shapiro, J; Thrupp, L D; Gandhi, S M; Sangha, S S; Miller, R B

1999-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

E-Print Network 3.0 - adolescent hiv infection Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Agents in HIV-1-Infected Adults and Adolescents (available at http:aidsinfo.nih.govguidelines). Summary: for the Use of Antiretroviral Agents in HIV-1-Infected Adults...

62

E-Print Network 3.0 - abuse hiv infection Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Agents in HIV-1-Infected Adults and Adolescents (available at http:aidsinfo.nih.govguidelines). Summary: for the Use of Antiretroviral Agents in HIV-1-Infected Adults...

63

Epidemiology of Malignant Tumors among HIV-infected Population in China  

E-Print Network [OSTI]

the HIV/AIDS Epidemic in China. 2010, Beijing. 21. RothmanCHINA. OF INCIDENT KAPOSI SARCOMA AMONG HIV/AIDS COHORT IN CHINA. (

Zhu, Weiming

2013-01-01T23:59:59.000Z

64

E-Print Network 3.0 - acyclovir delays hiv-1 Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary: 1 Transmission of HIV-1 minority resistant variants and response to first-line antiretroviral... : Transmission of minority resistant HIV-1 1 Table, 2 Figures Text...

65

E-Print Network 3.0 - appreciating hiv-1 diversity Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Strains in Newly- Summary: Cellular HIV-1 DNA Levels in Drug Sensitive Strains Are Equivalent to Those in Drug Resistant... , Leuven, Belgium Abstract Background: HIV-1...

66

E-Print Network 3.0 - adam hiv-1 non-nucleoside Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of HIV-1 Reverse Transcriptase Nonnucleoside Inhibitors: Correlation of Binding Energy with Biological Summary: HIV-1 non- nucleoside inhibitors from the HEPT and...

67

HIV-AIDS Information Resources from the NLM - ACIO  

SciTech Connect (OSTI)

As the treatment and management of HIV/AIDS continues to evolve with new scientific breakthroughs, treatment discoveries, and management challenges, it is difficult for people living with HIV/AIDS and those who care for them to keep up with the latest information on HIV/AIDS screening and testing, prevention, treatment, and research. The National Library of Medicine (NLM), of the National Institutes of Health, has a wealth of health information resources freely available on the Internet to address these needs.

Templin-Branner, W.

2010-10-01T23:59:59.000Z

68

Low dose rectal inoculation of rhesus macaques by SIV SME660 or SIV MAC251 recapitulates human mucosal infection by HIV-1  

SciTech Connect (OSTI)

Recently, we developed a novel approach to the identification of transmitted or early founder HIV -1 genomes in acutely infected humans based on single genome amplification and sequencing. Here we tested this approach in 18 acutely infected Indian rhesus macaques to determine the molecular features of SIV transmission. Animals were inoculated intrarectally (IR) or intravenously (IV) with stocks of SIVmac251 or SIVsmE660 that exhibited sequence diversity typical of early-chronic HIV -1 infection. 987 full-length SIV env sequences (median of 48 per animal) were determined from plasma virion RNA one to five weeks after infection. IR inoculation was followed by productive infection by one or few viruses (median 1; range 1-5) that diversified randomly with near star-like phylogeny and a Poisson distribution of mutations. Consensus viral sequences from ramp-up and peak viremia were identical to viruses found in the inocula or differed from them by only one or few nuc1eotides, providing direct evidence that early plasma viral sequences coalesce to transmitted/founder virus( es). IV infection was approximately 10,000-fold more efficient than IR infection, and viruses transmitted by either route represented the full genetic spectra of the inocula. These findings identify key similarities in mucosal transmission and early diversification between SIV and HIV -1.

Koraber, Bette [Los Alamos National Laboratory; Perelson, Alan [Los Alamos National Laboratory; Hraber, Peter [Los Alamos National Laboratory; Giorgi, E [Los Alamos National Laboratory; Bhattacharya, T [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

69

Early strawn biostratigraphy: What is the Caddo  

SciTech Connect (OSTI)

Caddo limestone is used to describe parts of the lower Strawn limestone on the Eastern shelf. The lower Strawn limestone as generally deposited on an eroded Ellenburger surface, but may overlie eroded Mississippian or even Atokan rocks preserved in topographic lows on the Ellenburger surface. Above the Caddo limestone is a sequence of clastics overlain by the Goen Limestone of early Strawn age. The Goen Limestone, in turn, is overlain by clastics which are overlain by the late Strawn Capps Limestone. As long as knowledge of fusulinid zonation was restricted to rocks of early Cherokee, late Cherokee, and Marmaton age, regional correlations of these carbonate units were manageable. With refinement of zonation, however, the Caddo, Goen, and Capps limestones can be subdivided into discrete units of different age. In each of these age zones, the units are further divisible on the basis of environments of deposition and subsequent diagenesis. Current results indicate that the early Strawn carbonates are cyclical and were deposited during numerous glacio-eustatic sea level fluctuations.

Reid, A.M.

1987-02-01T23:59:59.000Z

70

Early enlightenment in Istanbul  

E-Print Network [OSTI]

had emerged in medieval Konya, and ad- vocated thatearly age, mer moved to Konya, perhaps the most important

Kck, Bekir Harun

2012-01-01T23:59:59.000Z

71

Apply early! Limited enrollment.  

E-Print Network [OSTI]

volcano. Experience the culture and history of Hawaii, and the impact of human activitiesApply early! Limited enrollment. Environmental Science in the Hawaiian Islands Observe, research

72

ampliscreen hiv-1 test: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

ampliscreen hiv-1 test First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 The Fitness Landscape of HIV-1...

73

Identification of full-length transmitted/founder viruses and their progeny in primary HIV-1 infection  

SciTech Connect (OSTI)

Identification of transmitted/founder virus genomes and their progeny by is a novel strategy for probing the molecular basis of HIV-1 transmission and for evaluating the genetic imprint of viral and host factors that act to constrain or facilitate virus replication. Here, we show in a cohort of twelve acutely infected subjects (9 clade B; 3 clade C), that complete genomic sequences of transmitted/founder viruses could be inferred using single genome amplification of plasma viral RNA, direct amplicon sequencing, and a model of random virus evolution. This allowed for the precise identification, chemical synthesis, molecular cloning, and biological analysis of those viruses actually responsible for productive clinical infection and for a comprehensive mapping of sequential viral genomes and proteomes for mutations that are necessary or incidental to the establishment of HIV-1 persistence. Transmitted/founder viruses were CD4 and CCR5 tropic, replicated preferentially in activated primary T-Iymphocytes but not monocyte-derived macrophages, and were effectively shielded from most heterologous or broadly neutralizing antibodies. By 3 months of infection, the evolving viral quasispecies in three subjects showed mutational fixation at only 2-5 discreet genomic loci. By 6-12 months, mutational fixation was evident at 18-27 genomic loci. Some, but not all, of these mutations were attributable to virus escape from cytotoxic Tlymphocytes or neutralizing antibodies, suggesting that other viral or host factors may influence early HIV -1 fitness.

Korber, Bette [Los Alamos National Laboratory; Hraber, Peter [Los Alamos National Laboratory; Giorgi, Elena [Los Alamos National Laboratory; Bhattacharya, T [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

74

HIV transcription is induced with some forms of cell killing  

SciTech Connect (OSTI)

Using HeLa cells stably transfected with an HIV-LTR-CAT construct`, we demonstrated a peak in CAT induction that occurs in viable (but not necessarily cell-division-competent) cells 24 h following exposure to some cell-killing agents. {Gamma} rays were the only cell-killing agent which did not induce HIV transcription; this can be attributed to the fact that {gamma}-ray-induced apoptotic death requires function p53, which is missing in HeLa cells. For all other agents, HIV-LTR induction was dose-dependent and correlated with the amount of cell killing that occurred in the culture.

Woloschak, G.E. [Argonne National Lab., IL (United States); Schreck, S. [Argonne National Lab., IL (United States)][South Carolina Univ., Columbia, SC (United States). Dept. of Chemistry; Panozzo, J. [Loyola Univ. Medical Center, Maywood, IL (United States); Chang-Liu, C.-M. [Argonne National Lab., IL (United States); Libertin, C.R. [Loyola Univ. Medical Center, Maywood, IL (United States)

1996-11-01T23:59:59.000Z

75

Pioneering the nuclear age  

SciTech Connect (OSTI)

This paper reviews the historical aspects of nuclear physics. The scientific aspects of the early transuranium elements are discussed and arms control measures are reviewed. 11 refs., 14 figs. (LSP)

Seaborg, G.T.

1988-09-01T23:59:59.000Z

76

Parylene C Aging Studies.  

SciTech Connect (OSTI)

Parylene C is used in a device because of its conformable deposition and other advantages. Techniques to study Parylene C aging were developed, and %22lessons learned%22 that could be utilized for future studies are the result of this initial study. Differential Scanning Calorimetry yielded temperature ranges for Parylene C aging as well as post-deposition treatment. Post-deposition techniques are suggested to improve Parylene C performance. Sample preparation was critical to aging regimen. Short-term (~40 days) aging experiments with free standing and ceramic-supported Parylene C films highlighted %22lessons learned%22 which stressed further investigations in order to refine sample preparation (film thickness, single sided uniform coating, machine versus laser cutting, annealing time, temperature) and testing issues (%22necking%22) for robust accelerated aging of Parylene C.

Achyuthan, Komandoor; Sawyer, Patricia Sue.; Mata, Guillermo Adrian; White II, Gregory Von; Bernstein, Robert

2014-09-01T23:59:59.000Z

77

COOEE bitumen: chemical aging  

E-Print Network [OSTI]

We study chemical aging in "COOEE bitumen" using molecular dynamic simulations. The model bitumen is composed of four realistic molecule types: saturated hydrocarbon, resinous oil, resin, and asphaltene. The aging reaction is modelled by the chemical reaction: "2 resins $\\rightarrow$ 1 asphaltene". Molecular dynamic simulations of four bitumen compositions, obtained by a repeated application of the aging reaction, are performed. The stress autocorrelation function, the fluid structure, the rotational dynamics of the plane aromatic molecules, and the diffusivity of each molecule, are determined for the four different compositions. The aging reaction causes a significant dynamics slowdown, which is correlated to the aggregation of asphaltene molecules in larger and dynamically slower nanoaggregates. Finally, a detailed description of the role of each molecule types in the aggregation and aging processes is given.

Lemarchand, Claire A; Dyre, Jeppe C; Hansen, Jesper S

2013-01-01T23:59:59.000Z

78

Children Are the Wealth of the Poor: Prevention of Mother-to-Child Transmission of HIV in Haiti  

E-Print Network [OSTI]

At roughly two percent, Haiti has one of the highest HIV prevalence rates in the Caribbean. This thesis examines HIV transmission in Haiti, specifically the transmission of HIV from mother to child during pregnancy, labor, ...

Denney, Rachel

2012-08-31T23:59:59.000Z

79

AIDS. Author manuscript Early antiretroviral therapy of HIV-infected infants in resource-limited  

E-Print Network [OSTI]

: U897, Universit Victor Segalen - Bordeaux IIé , FR Pediatric, Adolescent, and Maternal AIDS Branch3 are receiving therapy . Barriers to pediatric treatment include lack of appropriate testing technology% [10 pediatric antiretroviral drug formulations, lack of personnel with health care expertise in treatment

Boyer, Edmond

80

Essays on HIV/AIDS in sub-Saharan Africa  

E-Print Network [OSTI]

HIV-1 Prenvetion SErvices in Dar Es Salaam, Tanzania: Thein Nairobi, Kenya and Dar Es Salaam, Tanzania. In bothurban Kenya (13-14%) and Dar es Salaam, Tanzania (10-12%) (

Gong, Erick Joseph

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Emerging nanotechnology approaches for HIV/AIDS treatment and prevention  

E-Print Network [OSTI]

Emerging nanotechnology approaches for HIV/AIDS treatment and prevention The emergence of AIDS effects and is ineffective in patients in whom the virus develops resistance. Nanotechnology of nanotechnology to provide more effective treatment and preven

von Andrian, Ulrich H.

82

antenatal hiv testing: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HIV Testing Day (NHTD) is June 27. NHTD is sponsored by the National Association of People with AIDS to encourage persons at risk to receive voluntary counseling and testing for...

83

Additivity in the Analysis and Design of HIV Protease Inhibitors  

E-Print Network [OSTI]

We explore the applicability of an additive treatment of substituent effects to the analysis and design of HIV protease inhibitors. Affinity data for a set of inhibitors with a common chemical framework were analyzed to ...

Jorissen, Robert N.

84

An age-structured model for the coupled dynamics of HIV and HSV-2  

E-Print Network [OSTI]

Profesor Asociado a la Facultad de Ingenieria y Ciencias de la Universidad Adolfo Ibanez, Santiago, Chile. Zhilan Feng. Department of Mathematics, Purdue

2014-12-24T23:59:59.000Z

85

The development of early terrestrial ecosystems  

E-Print Network [OSTI]

,575-599. Burgess, N.D. & Edwards, D. (1991). Classification of uppermost Ordovician to Lower Devonian tubular and filamentous macerals from the Anglo-Welsh Basin. Botanical Journal of the Linnean Society 106,41-66. Campbell, S.E. (1979). Soil stabilization...., Massa, D. & Boucot A J . (1982). Caradocian land plant microfossils from Libya. Geology 10.197-201. Gray, J., Theron, J.N. & Boucot, A J . (1986). Age of the Cedarberg Formation, South Africa and early land plant evolution. Geological Magazine 123...

Selden, Paul A.; Edwards, Dianne

1993-01-01T23:59:59.000Z

86

Impact of HIV/AIDS on the Agricultural Sector in Northern Namibia  

E-Print Network [OSTI]

In agrarian societies, HIV/AIDS extends far beyond the realm of healthcare into agricultural production and food security as well. Namibia is a developing country with a large portion of its population involved in agriculture; the average HIV...

Carter, Charles Russell

2011-02-22T23:59:59.000Z

87

E-Print Network 3.0 - aids-free hiv-1-infected patients Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

free hiv-1-infected patients Search Powered by Explorit Topic List Advanced Search Sample search results for: aids-free hiv-1-infected patients Page: << < 1 2 3 4 5 > >> 1 AIDS...

88

Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens  

DOE Patents [OSTI]

The present invention relates to mosaic clade M HIV-1 Env polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Korber, Bette T. (Los Alamos, NM); Fischer, William (Los Alamos, NM); Liao, Hua-Xin (Durham, NC); Haynes, Barton F. (Durham, NC); Letvin, Norman (Boston, MA); Hahn; Beatrice H. (Birmingham, AL)

2011-05-31T23:59:59.000Z

89

E-Print Network 3.0 - access hiv services Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HIV Summary: on the prevention of HIV and STIs to women who do not frequently access health care services. Although prenatal care... fees. Mother-infant pairs had access to...

90

Original article Response of Pinus pinaster Ait. provenances at early  

E-Print Network [OSTI]

. pinaster in response to water shortage. These physiological adaptations complement known morphologicalOriginal article Response of Pinus pinaster Ait. provenances at early age to water supply. I. Water evolution of tissue water relations was assessed in 1-year-old seedlings of four Pinus pinaster Ait. prove

Paris-Sud XI, Universit de

91

ORIGINAL PAPER Recognition of early Carboniferous alkaline granite  

E-Print Network [OSTI]

ORIGINAL PAPER Recognition of early Carboniferous alkaline granite in the southern Altai orogen for the Bulgen alkaline granite yield crystallization ages of 358 ± 4 Ma (SHRIMP) and 354 ± 4 Ma (LA-orogenic granitoids (460­375 Ma) in this region. The Bulgen granite has high SiO2, total alkalis, rare earth elements

Siebel, Wolfgang

92

New Age Teaching: Beyond Didactics  

E-Print Network [OSTI]

Age Teaching: Beyond Didactics TheScientificWorldJOURNAL (New age teaching: beyond didactics. TSW Urology 1, 7585.New Age Teaching: Beyond Didactics Peter D. Vlaovic and

Vlaovic, Peter D; McDougall, Elspeth M

2006-01-01T23:59:59.000Z

93

Development of Personality in Early and Middle Adulthood: Set Like Plaster or Persistent Change?  

E-Print Network [OSTI]

Development of Personality in Early and Middle Adulthood: Set Like Plaster or Persistent Change-factor theory proposes the plaster hypothesis: All personality traits stop changing by age 30. In contrast

Pillow, Jonathan

94

Predicting School Readiness for Low-Income Children With Disability Risks Identified Early.  

E-Print Network [OSTI]

This study examined school readiness at kindergarten entry for low-income children whose disability indicators were identified before age 3. Data were collected as part ofthe Early Head Start Research and Evaluation ...

Jeon, Hyun-Joo; Peterson, Carla A.; Wall, Shavaun; Carta, Judith J.; Gayle, Luze; Eshbaugh, Elaine M.; Swanson, Mark

2011-01-01T23:59:59.000Z

95

Bitcoin and The Age of Bespoke Silicon Michael Bedford Taylor  

E-Print Network [OSTI]

Bitcoin and The Age of Bespoke Silicon Michael Bedford Taylor University of California, San Diego ABSTRACT Recently, the Bitcoin cryptocurrency has been an interna- tional sensation. This paper tells the story of Bitcoin hard- ware: how a group of early-adopters self-organized and fi- nanced the creation

Wang, Deli

96

Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal  

E-Print Network [OSTI]

Health and Interventions to Reduce Perinatal HIV Transmission in the United States Developed by the HHS Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission--A Working: Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission

Levin, Judith G.

97

E-Print Network 3.0 - age distribution genetics Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

10.1534genetics.108.086801 Summary: across all ages. This result implies a genetic trade-off between the two traits in early lifeand may help... of environmental conditions on...

98

E-Print Network 3.0 - age-related white matter Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

white matter Search Powered by Explorit Topic List Advanced Search Sample search results for: age-related white matter Page: << < 1 2 3 4 5 > >> 1 Assessing Early Brain Development...

99

Counting Guns in Early America  

E-Print Network [OSTI]

Bang! Historian Explodes American Gun Myths, M INN . S TAR Tat 339-40 (1994). Counting Guns in Early America, Wm. & Maryto estimate levels of gun ownership in early America. This

Lindgren, James

2002-01-01T23:59:59.000Z

100

Aging in community  

E-Print Network [OSTI]

Baby Boomers are on the brink of retirement. According to U.S. Census Bureau projections, the number of people aged 65 and over will more than double in the coming decades, growing from 35 million in 2000 to 72 million in ...

Fay, Justin (Justin Thomas)

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Early Lessons Learned  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series toESnet4: Networking for the Future of DOE ScienceEarly EdisonLessons

102

SAARC J. TUBER. LUNG DIS. HIV/AIDS 2008 V (1)......... OPPORTUNISTIC INTESTINAL PROTOZOAN PARASITIC INFECTION IN HIV POSITIVE PATIENT IN JAMNAGAR, GUJARAT  

E-Print Network [OSTI]

The case definition of AIDS encompasses a spectrum of infections and malignancies, labelled as opportunistic infections. In recent years, numerous studies have outlined the emergence of opportunistic gastrointestinal protozoa that have caused diarrhoeal illness among HIV AIDS patients. Purpose of present study was to determine the prevalence of opportunistic intestinal protozoal parasites in HIV positive patients with or without diarrhoea. A total of 100 stool samples of HIV positive patients were examined for protozoal parasites by microscopy. Protozoal parasites were detected in 25 HIV positive patients; in 41.37 % of patients with diarrhoea and in 2.38 % of patients without diarrhoea. Isospora belli appeared to be a predominant parasite associated with diarrhoea among HIV patients. Cryptosporidium revealed of its asymptomatic carriage along with its association with acute and chronic diarrhoea. Prevalence of Microsporidia and Cyclospora cayetenensis was found to be very low. Key words: HIV, diarrhoea, opportunistic protozoa.

Gupta M; Sinha M; Raizada N

103

Concrete containment aging study  

SciTech Connect (OSTI)

In 1989, IAEA initiated a pilot study on the management of aging of nuclear power plant components. The Phase I and II studies of concrete containment are discussed. With the data base, plant owners will be able to review and enhance their existing programs. IAEA will analyze data provided by participating plants and the report is scheduled to be released by late 1994 (final report release mid-1995).

Pachner, J. [International Atomic Energy Agency, Vienna (Austria); Tai, T.M. [Bechtel National, Inc., Oak Ridge, TN (United States); Naus, D. [Oak Ridge National Lab., TN (United States)

1994-04-01T23:59:59.000Z

104

Wrapping up the bad news - HIV assembly and release  

E-Print Network [OSTI]

comprising four major subdomains Matrix (MA), Capsid (CA), Nucleocapsid (NC) and p6. Flanking NC are two small spacer peptides SP1 (p2) and SP2 (p1). The assembly of capsid like particles in HIV and other retroviruses can be achieved by the viral Gag pro... in HIV is now understood in remarkable detail; however, there are some notable unanswered questions. tic extended Gag assemblies with dimensions compa- rable to a wild type viral capsid can be formed in the presence of lipid membranes and nucleic acid...

Meng, Bo; Lever, Andrew ML

2013-01-10T23:59:59.000Z

105

Early Customer Involvement in Innovation.  

E-Print Network [OSTI]

?? The Front End of innovation (FEI) or early innovation presents one of the greatest opportunities for improving an entire innovation process in any firm. (more)

Penn, Sylvain Bienvenu

2011-01-01T23:59:59.000Z

106

receive DOE Early Career Award  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

hydrological controls on carbon cycling in flood plain ecosystems into Earth System Models (ESM). "The DOE Early Career Research Award represents both a significant honor...

107

access hiv-1 test: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

access hiv-1 test First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 REVIEW Open Access The macrophage in...

108

Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease  

SciTech Connect (OSTI)

Under drug selection pressure, emerging mutations render HIV-1 protease drug resistant, leading to the therapy failure in anti-HIV treatment. It is known that nine substrate cleavage site peptides bind to wild type (WT) HIV-1 protease in a conserved pattern. However, how the multidrug-resistant (MDR) HIV-1 protease binds to the substrate cleavage site peptides is yet to be determined. MDR769 HIV-1 protease (resistant mutations at residues 10, 36, 46, 54, 62, 63, 71, 82, 84, and 90) was selected for present study to understand the binding to its natural substrates. MDR769 HIV-1 protease was co-crystallized with nine substrate cleavage site hepta-peptides. Crystallographic studies show that MDR769 HIV-1 protease has an expanded substrate envelope with wide open flaps. Furthermore, ligand binding energy calculations indicate weaker binding in MDR769 HIV-1 protease-substrate complexes. These results help in designing the next generation of HIV-1 protease inhibitors by targeting the MDR HIV-1 protease.

Liu, Zhigang; Wang, Yong; Brunzelle, Joseph; Kovari, Iulia A.; Kovari, Ladislau C. (WSU-MED); (NWU)

2012-03-27T23:59:59.000Z

109

Early Entrance Coproduction Plant  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstocks. The objectives of Phase I were to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan for implementation in Phase II; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The work performed under Phase II will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and/or other carbonaceous feedstocks. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation.

Mushtaq Ahmed; John H. Anderson; Earl R. Berry; Troy Raybold; Lalit S. Shah; Kenneth A. Yackly

2004-01-26T23:59:59.000Z

110

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstocks. The objectives of Phase I were to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan for implementation in Phase II; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The work performed under Phase II will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and/or other carbonaceous feedstocks. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation.

Mushtaq Ahmed; John H. Anderson; Earl R. Berry; Troy Raybold; Lalit S. Shah; Kenneth A. Yackly

2003-12-16T23:59:59.000Z

111

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which produces at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstock. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site and to develop a Research, Development, and Testing Plan (RD and T) for implementation in Phase II. The objective of Phase II is to implement the RD and T as outlined in the Phase I RD and T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The project will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and other feedstocks. The objective of Phase III is to develop an engineering design package and a financing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information that will be needed to move the EECP forward to detailed design, construction, and operation by industry.

John S. Abughazaleh; Mushtaq Ahmed; Ashok Anand; John H. Anderson; Charles Benham; Fred D. Brent; Thomas E. Chance; William K. Davis; Raymond F. Drnevich; Larry Hall; Ming He; Stephen A. Lang; Jimmy O. Ong; Sarah J. Patel; George Potoczniak; Adela G. Sanchez; Charles H. Schrader; Lalit S. Shah; Phil J. Shires; Rae Song

2000-10-26T23:59:59.000Z

112

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which produces at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstocks. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site and to develop a Research, Development, and Testing Plan (RD and T) for implementation in Phase II. The objective of Phase II is to implement the RD and T as outlined in the Phase I RD and T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The project will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and/or other carbonaceous feedstocks. The objective of Phase III is to develop an engineering design package and a financing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information that will be needed to move the EECP forward to detailed design, construction, and operation by industry.

John S. Abughazaleh; Mushtaq Ahmed; Ashok Anand; John H. Anderson; Charles Benham; Fred D. Brent; Thomas E. Chance; William K. Davis; Raymond F. Drnevich; Larry Hall; Ming He; Stephen A. Lang; Jimmy O. Ong; Sarah J. Patel; George Potoczniak; Adela G. Sanchez; Charles H. Schrader; Lalit S. Shah; Phil J. Shires; Rae Song

2001-02-15T23:59:59.000Z

113

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three-phase development of an Early Entrance Coproduction Plant (EECP) that produces at least one product from at least two of the following three categories: Electric power (or heat); Fuels; and Chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or some other carbonaceous feedstock, such as petroleum coke. The objective of Phase I was to determine the feasibility and define the concept for the EECP located at a specific site and to develop a Research, Development, and Testing (RD and T) Plan for implementation in Phase II. This objective has now been accomplished. A specific site, Motiva Refinery in Port Arthur, Texas, has been selected as the location best suited for the EECP. The accomplishments of Phase I are discussed in detail in this Phase I Concept Report. A RD and T Plan and a preliminary project financing plan have been developed and are submitted separately from this report.

John S. Abughazaleh; Mushtaq Ahmed; Ashok Anand; John H. Anderson; Charles Benham; Fred D. Brent; Thomas E. Chance; William K. Davis; Raymond F. Drnevich; Larry Hall; Ming He; Stephen A. Lang; David Mintner; Wendy Moore; Jimmy O. Ong; George Potoczniak; Adela G. Sanchez; Charles H. Schrader; Lalit S. Shah; Kalapi D. Sheth; Phil J. Shires; Rae Song

2001-05-17T23:59:59.000Z

114

Tobacco use in HIV infected patients; Second Revised manuscript ID AVT-07-OA-0582 Living With HIV, Antiretroviral Treatment Experience  

E-Print Network [OSTI]

, Antiretroviral Treatment Experience and Tobacco Smoking: Results From a Multi-Site Cross-Sectional Study a Xavier-infected patient care were asked to complete a self-administered questionnaire, assessing smoking habits, dependence, cessation motivation, other substance abuse, socio-cultural characteristics, life with HIV

Paris-Sud XI, Université de

115

CHERRY: CHECKPOINTED EARLY RESOURCE RECYCLING  

E-Print Network [OSTI]

1 2 3 CHERRY: CHECKPOINTED EARLY RESOURCE RECYCLING Jos´e F. Mart´inez1 , Jose Renau2 Michael C. Huang3 , Milos Prvulovic2 , and Josep Torrellas2 #12;Cherry: Checkpointed Early Resource Recycling efficient use by aggressive recycling Opportunity: Resources reserved until retirement § ¦ ¤ ¥ Solution

Torrellas, Josep

116

Training for Early Career Researchers  

E-Print Network [OSTI]

Training for Early Career Researchers Research Management Training for 16 ­ 17 September 2014 training in an intensive, yet effective workshop form over two days. There is a strong emphasis on European Management Training for Early Career Researchers 16 ­ 17 September 2014 in Hamburg #12;

Greifswald, Ernst-Moritz-Arndt-Universität

117

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

As part of the Department of Energy's (DOE) Gasification Technologies and Transportation Fuels and Chemicals programs, DOE and Texaco are partners through Cooperative Agreement DE-FC26-99FT40658 to determine the feasibility of developing, constructing and operating an Early Entrance Coproduction Plant (EECP). The overall objective of the project is the three-phase development of an EECP that produces at least one product from at least two of the following three categories: Electric power (or heat); Fuels; and Chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or some other carbonaceous feedstock, such as petroleum coke. The objective of Phase I was to determine the feasibility and define the concept for the EECP located at a specific site and to develop a Research, Development, and Testing (RD and T) Plan for implementation in Phase II. This objective has now been accomplished. A specific site, Motiva Refinery in Port Arthur, Texas, has been selected as the location best suited for the EECP. The specific work requirements of Phase I included: Prepare an EECP Preliminary Concept Report covering Tasks 2-8 specified in the Cooperative Agreement; Develop a Research, Development, and Testing (RD and T) Plan as specified in Task 9 of the Cooperative Agreement for implementation in Phase II; and Develop a Preliminary Project Financing Plan for the EECP Project as specified in Task 10 of the Cooperative Agreement. This document is the Preliminary Project Financing Plan for the design, construction, and operation of the EECP at the Motiva Port Arthur Refinery.

John H. Anderson; William K. Davis; Thomas W. Sloop

2001-03-21T23:59:59.000Z

118

THE EFFECTS OF HIV INFECTION ON THE EXPRESSION OF THE DRUG EFFLUX PROTEINS P-GLYCOPROTEIN AND BREAST CANCER RESISTANCE PROTEIN IN A HUMAN INTESTINE MODEL  

E-Print Network [OSTI]

Background: Emerging evidence suggests poor antiretroviral penetration within human gastrointestinal (GI) tissues may contribute to HIV persistence within reservoirs despite effective therapy. We hypothesize that HIV ...

Ellis, Kelstan Lynch

2012-08-31T23:59:59.000Z

119

An audit of the standard of care received by HIV positive patients on ART at a community health centre in KZN.  

E-Print Network [OSTI]

??Introduction: South Africa has the highest number of HIV infected individuals in the world.2 The South African government has established National treatment guidelines for HIV (more)

Inderjeeth, Nishana.

2015-01-01T23:59:59.000Z

120

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. Each of the EECP subsystems was assessed for technical risks and barriers. A plan was developed to mitigate the identified risks (Phase II RD&T Plan, October 2000). The potential technical and economic risks to the EECP from Task 2.5 can be mitigated by demonstrating that the end-use products derived from the upgrading of the F-T synthesis total liquid product can meet or exceed current specifications for the manufacture of ethylene and propylene chemicals from F-T naphtha, for the generation of hydrogen from F-T naphtha to power fuel cells, for direct blending of F-T diesels into transportation fuels, for the conversion of F-T heavy product wax to transportation fuels, and the conversion of F-T Heavy product wax to a valuable high melting point food-grade specialty wax product. Product evaluations conducted under Task 2.5 of Phase II successfully mitigated the above technical and economic risks to the EECP with the development of product yields and product qualities for the production of chemicals, transportation fuels, and specialty food-grade waxes from the F-T synthesis products.

Fred D. Brent; Lalit Shah; Earl Berry; Charles H. Schrader; John Anderson; Ming He; James F. Stevens; Centha A. Davis; Michael Henley; Jerome Mayer; Harry Tsang; Jimell Erwin; Jennifer Adams; Michael Tillman; Chris Taylor; Marjan J. Roos; Robert F. Earhart

2004-01-27T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, Inc., GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. During Phase I, a design basis for the Fischer-Tropsch Synthesis section was developed based on limited experience with the specified feed gas and operating conditions. The objective of this Task in Phase II RD&T work was to confirm the performance of the F-T reactor at the set design conditions. Although much of the research, development, and testing work were done by TES outside of this project, several important issues were addressed in this phase of the project. They included Rejuvenation/Regeneration of the Fischer-Tropsch Catalyst, online Catalyst Withdrawal and Addition from the synthesis reactor, and the Fischer-Tropsch Design Basis Confirmation. In Phase III the results from these RD&T work will be incorporated in developing the engineering design package. This Topical Report documents the Phase II RD&T work that was completed for this task.

David Storm; Govanon Nongbri; Steve Decanio; Ming He; Lalit Shah; Charles Schrader; Earl Berry; Peter Ricci; Belma Demirel; Charles Benham; Mark Bohn

2004-01-12T23:59:59.000Z

122

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

In 1999, the U. S. Department of Energy (DOE) awarded a Cooperative Agreement to Texaco Energy Systems Inc. to provide a preliminary engineering design of an Early Entrance Coproduction Plant (EECP). Since the award, continuous and diligent work has been undertaken to achieve the design of an economical facility that makes strides toward attaining the goal of DOE's Vision 21 Program. The objective of the EECP is to convert coal and/or petroleum coke to power while coproducing transportation fuels, chemicals, and useful utilities such as steam. This objective is being pursued in a three-phase effort through the partnership of the DOE with prime contractor Texaco Energy Systems, LLC. (TES), the successor to Texaco Energy Systems, Inc. The key subcontractors to TES include General Electric (GE), Praxair, and Kellogg Brown and Root. ChevronTexaco provided gasification technology and Rentech Inc.'s Fischer-Tropsch (F-T) technology that has been developed for non-natural gas sources. GE provided gas turbine technology for the combustion of low energy content gas. Praxair provided air separation technology and KBR provided engineering to integrate the facility. A conceptual design was completed in Phase I and the report was accepted by the DOE in May 2001. The Phase I work identified risks and critical research, development, and testing that would improve the probability of technical success of the EECP. The objective of Phase II was to mitigate the risks by executing research, development, and testing. Results from the Phase II work are the subject of this report. As the work of Phase II concluded, it became evident that sufficient, but not necessarily complete, technical information and data would be available to begin Phase III - Preliminary Engineering Design. Work in Phase II requires additional technical development work to correctly apply technology at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The decision to proceed with Phase III centers on locating a new site and favorable commercial and economic factors.

John Anderson; Charles Schrader

2004-01-26T23:59:59.000Z

123

Living and Dying Abroad: Aspects of Egyptian Cultural Identity in Late Bronze Age and Early Iron Age Canaan  

E-Print Network [OSTI]

Encyclopedia of Ancient Egypt. Volume I. Oxford. 161-162.1994 Amulets of Ancient Egypt. London. Anzalda, G. 1987Encyclopedia of Ancient Egypt. Volume III. Oxford. 179-181.

Pierce, Krystal Victoria Lords

2013-01-01T23:59:59.000Z

124

Living and Dying Abroad: Aspects of Egyptian Cultural Identity in Late Bronze Age and Early Iron Age Canaan  

E-Print Network [OSTI]

on the doorjamb read k Htp r st=f n ( content in hison the doorjamb read k Htp r st=f n, meaning content inprescriptions of the Egyptian Htp di nsw (Holthoer 1977:

Pierce, Krystal Victoria Lords

2013-01-01T23:59:59.000Z

125

Aging and functional brain networks  

SciTech Connect (OSTI)

Aging is associated with changes in human brain anatomy and function and cognitive decline. Recent studies suggest the aging decline of major functional connectivity hubs in the 'default-mode' network (DMN). Aging effects on other networks, however, are largely unknown. We hypothesized that aging would be associated with a decline of short- and long-range functional connectivity density (FCD) hubs in the DMN. To test this hypothesis, we evaluated resting-state data sets corresponding to 913 healthy subjects from a public magnetic resonance imaging database using functional connectivity density mapping (FCDM), a voxelwise and data-driven approach, together with parallel computing. Aging was associated with pronounced long-range FCD decreases in DMN and dorsal attention network (DAN) and with increases in somatosensory and subcortical networks. Aging effects in these networks were stronger for long-range than for short-range FCD and were also detected at the level of the main functional hubs. Females had higher short- and long-range FCD in DMN and lower FCD in the somatosensory network than males, but the gender by age interaction effects were not significant for any of the networks or hubs. These findings suggest that long-range connections may be more vulnerable to aging effects than short-range connections and that, in addition to the DMN, the DAN is also sensitive to aging effects, which could underlie the deterioration of attention processes that occurs with aging.

Tomasi D.; Tomasi, D.; Volkow, N.D.

2011-07-11T23:59:59.000Z

126

Proteomic Analysis of Saliva in HIV-positive Heroin Addicts Reveals Proteins Correlated with Cognition  

SciTech Connect (OSTI)

The prevalence of HIV-associated neurocognitive disorders (HAND) remains high despite effective antiretroviral therapies. Multiple etiologies have been proposed over the last few years to account for this phenomenon, including the neurotoxic effects of antiretrovirals and co-morbid substance abuse. However, no underlying molecular mechanism has been identified. Emerging evidence in several fields has linked the gut to brain diseases, but the effect of the gut on the brain during HIV infection has not been explored. Saliva is the most accessible gut biofluid, and is therefore of great scientific interest for diagnostic and prognostic purposes. This study presents a longitudinal, liquid chromatography-mass spectrometry-based quantitative proteomics study investigating saliva samples taken from 8 HIV-positive (HIV+) and 11 -negative (HIV-) heroin addicts. In the HIV+ group, 58 proteins were identified that show significant correlations with cognitive scores and that implicate disruption of protein quality control pathways by HIV. Notably, no proteins from the HIV- heroin addict cohort showed significant correlations with cognitive scores. In addition, the majority of correlated proteins have been shown to be associated with exosomes, allowing us to propose that the salivary glands and/or oral epithelium may modulate brain function during HIV infection through the release of discrete packets of proteins in the form of exosomes.

Dominy, Stephen; Brown, Joseph N.; Ryder, Mark I.; Gritsenko, Marina A.; Jacobs, Jon M.; Smith, Richard D.

2014-04-01T23:59:59.000Z

127

Living with HIV in Egypt : an analysis of needs and caregivers' burden and strain.  

E-Print Network [OSTI]

??As we enter the third decade of a devastating worldwide epidemic, much has been done to stem the flow of HIV/AIDS, in particular within North (more)

Lashein, Adel.

2008-01-01T23:59:59.000Z

128

E-Print Network 3.0 - anti-hiv activity evaluation Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Agents in HIV-1-Infected Adults and Adolescents (available at http:aidsinfo.nih.govguidelines). Summary: :aidsinfo.nih.govguidelines). What is treatment failure?...

129

E-Print Network 3.0 - architect hiv ag Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

article Pattern of neuropsychological performance among HIV positive patients in Uganda Kevin R Robertson... @jhmi.edu * Corresponding author Abstract Background: Few studies...

130

E-Print Network 3.0 - asymptomatic chronic hiv Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

article Pattern of neuropsychological performance among HIV positive patients in Uganda Kevin R Robertson... @jhmi.edu * Corresponding author Abstract Background: Few studies...

131

Script generation and multitasking in HIV-1 infection : implications for everyday functioning  

E-Print Network [OSTI]

Gagnon S. (2004). Script generation following frontal andGroup. (2005). Action (verb) generation in HIV-1 infection.Note. SG = Script Generation test; MT = Multitasking test. *

Scott, James Cobb

2009-01-01T23:59:59.000Z

132

E-Print Network 3.0 - acute hiv-1 infection Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

-matched seronegative controls. Of the HIV-1-infected individuals, 65 were stud- ied during the acute stage of ... Source: Collection: Biology and Medicine 25 JOURNAL OF...

133

DLM Early Childhood Express: Assessment in Early Childhood  

E-Print Network [OSTI]

DLM Early Childhood Express Assessment in Early Childhood Dr. Rafael Lara-Alecio a-lara@neo.tamu.edu Dr. Beverly J. Irby edu_bid@shsu.edu What principles guide assessment for effectively improving student learning? ? Assessment is inherently... a process of professional judgment. ? Assessment is based on separate but related principles of measurement evidence and evaluation. ? Assessment decision-making is influenced by a series of tensions. ? Assessment influences student motivation...

Lara-Alecio, Rafael; Irby, Beverly J.

2010-10-22T23:59:59.000Z

134

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. During Phase I the team identified several potential methods to reduce or minimize the environmental impact of the proposed EECP. The EECP Project Team identified F-T catalyst disposal, beneficial gasifier slag usage (other than landfill), and carbon dioxide recovery for the gas turbine exhaust for study under this task. Successfully completing the Task 2.10 RD&T provides additional opportunities for the EECP to meet the goals of DOE's Vision 21 Program. The gasification section offers several opportunities to maximize the environmental benefits of an EECP. The spent F-T catalyst can be sent to landfills or to the gasification section. Testing in Phase II shows that the spent F-T catalyst with a small wax coating can safely meet federal landfill requirements. As an alternative to landfilling, it has been proposed to mix the spent F-T catalyst with the petroleum coke and feed this mixture to the gasification unit. Based on ChevronTexaco's experience with gasification and the characteristics of the spent F-T catalyst this appears to be an excellent opportunity to reduce one potential waste stream. The slag from the gasification unit can be commercially marketed for construction or fuel (such as cement kiln fuel) uses. The technical and economic benefits of these options must be reviewed for the final EECP before incorporating a specific alternative into the design basis. Reducing greenhouse gas emissions, particularly carbon dioxide, is an important goal of the EECP. The Texaco gasification process provides opportunities to capture high purity streams of carbon dioxide. For Phase II, a carbon fiber composite molecular sieve (CFCMS) was tested to determine its potential to remove high purity carbon dioxide from the exhaust of a gas turbine. Testing on with a simulated gas turbine exhaust shows that the CFCMS is able to remove high purity carbon dioxide from the exhaust. However, more development is required to optimize the system.

John H. Anderson; Charles Benham; Earl R. Berry; Ming He; Charles H. Schrader; Lalit S. Shah; O.O. Omatete; T.D. Burchell

2004-01-12T23:59:59.000Z

135

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC (TES), a subsidiary of ChevronTexaco, General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, Inc. GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. Each of the EECP subsystems were assessed for technical risks and barriers. A plan was identified to mitigate the identified risks (Phase II RD&T Plan, October 2000). The RD&T Plan identified catalyst/wax separation as a potential technical and economic risk. To mitigate risks to the proposed EECP, Phase II RD&T included tests of an alternative (to Rentech's Dynamic Settler) primary catalyst/wax separation device and secondary catalyst/wax separation systems. The team evaluated multiple technologies for both primary and secondary catalyst/wax separation. Based on successful testing at Rentech (outside of DOE funding) and difficulties in finalizing a contract to demonstrate alternative primary catalyst/wax separation technology (using magnetic separation technology), ChevronTexaco has selected the Rentech Dynamic Settler for primary catalyst/wax separation. Testing has shown the Dynamic Settler is capable of producing filtrate exceeding the proposed EECP primary catalyst/wax separation goal of less than 0.1 wt%. The LCI Scepter{reg_sign} Microfiltration system appeared to be best suited for producing a filtrate that met the EECP secondary catalyst/wax separation standards of 10 parts per million (weight) [ppmw]. The other technologies, magnetic separation and electrostatic separation, were promising and able to reduce the solids concentrations in the filtrate. Additional RD&T will be needed for magnetic separation and electrostatic separation technologies to obtain 10 ppmw filtrate required for the proposed EECP. The Phase II testing reduces the technical and economic risks and provides the information necessary to proceed with the development of an engineering design for the EECP Fischer-Tropsch catalyst/wax separation system.

John Anderson; Mark Anselmo; Earl Berry; Mark Bohn; Roko Bujas; Ming He; Ken Kwik; Charles H. Schrader; Lalit Shah; Dennis Slater; Donald Todd; Don Wall

2003-08-21T23:59:59.000Z

136

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to its detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC (TES) (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR). The work was under cooperative agreements with the U.S. Department of Energy (DOE). TES is providing the gasification technology and the Fischer-Tropsch (F-T) technology developed by Rentech Inc., GE is providing the combustion turbine technology, Praxair is providing the air separation technology, and KBR is providing overall engineering. Each of the EECP's subsystems was assessed for technical risks and barriers in Phase I. A plan was identified to mitigate the identified risks (Phase II RD&T Plan, October 2000). The RD&T Plan identified catalyst/wax separation as a potential technical and economic risk. To mitigate risks to the proposed EECP concept, Phase II RD&T included tests for secondary catalyst/wax separation systems as part of Task 2.3--Catalyst/Wax Separation. The LCI Scepter{reg_sign} Microfiltration system was determined to be best suited for producing a filtrate that met the EECP secondary catalyst/wax separation standards of producing F-T wax containing less than10 ppmw solids. As part of task 2.3, micro-filtration removal efficiencies and production rates for two FT feeds, Rentech Inc. bubble column reactor (BCR) product and LaPorte Alternative Fuels Development Unit (AFDU) product, were evaluated. Based on comparisons between the performances of these two materials, the more readily available LaPorte AFDU material was judged an acceptable analog to the BCR material that would be produced in a larger-scale F-T synthesis. The present test was initiated to obtain data in an extended range of concentration for use in the scale-up design of the secondary catalyst/wax separation system that would be operating at the EECP capacity.

John Anderson; Mark Anselmo; Earl Berry; Mark Bohn; Ming He; Charles H. Schrader; Lalit Shah; Donald Todd; Robert Schavey

2004-01-12T23:59:59.000Z

137

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which produces at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using petroleum coke and ChevronTexaco's proprietary gasification technology. The objective of Phase I was to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC. (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). ChevronTexaco is providing gasification technology and Fischer-Tropsch technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology and KBR is providing engineering. Each of the EECP subsystems were assessed for technical risks and barriers. A plan was identified to mitigate the identified risks (Phase II RD&T Plan, October 2000). The RD&T Plan identified F-T reactor scale-up as a potential technical risk. The objective of Task 2.3 was to confirm engineering models that allow scale-up to commercial slurry phase bubble column (SPBC) reactors operating in the churn-turbulent flow regime. In developmental work outside the scope of this project, historical data, literature references, and a scale-up from a 1 1/2-in. (3.8 cm) to 6-ft (1.8 m) SPBC reactor have been reviewed. This review formed the background for developing scale-up models for a SPBC reactor operating in the churn-turbulent flow regime. The necessary fundamental physical parameters have been measured and incorporated into the mathematical catalyst/kinetic model developed from the SPBC and CSTR work outside the scope of this EECP project. The mathematical catalyst/kinetic model was used to compare to experimental data obtained at Rentech during the EECP Fischer-Tropsch Confirmation Run (Task 2.1; reported separately). The prediction of carbon monoxide (CO) conversion as a function of days on stream compares quite closely to the experimental data.

Randy Roberts

2003-04-25T23:59:59.000Z

138

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which produces at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. During Phase I the team identified the integration of the water produced in the F-T synthesis section with the gasification section as an area of potential synergy. By utilizing the F-T water in the petroleum coke slurry for the gasifier, the EECP can eliminate a potential waste stream and reduce capital costs. There is a low technical risk for this synergy, however, the economic risk, particularly in regards to the water, can be high. The economic costs include the costs of treating the water to meet the locally applicable environmental standards. This option may require expensive chemicals and treatment facilities. EECP Phase II included tests conducted to confirm the viability of integrating F-T water in the slurry feed for the gasifier. Testing conducted at ChevronTexaco's Montebello Technology Center (MTC) included preparing slurries made using petroleum coke with F-T water collected at the LaPorte Alternative Fuels Development Unit (AFDU). The work included bench scale tests to determine the slurry ability of the petroleum coke and F-T water. The results of the tests show that F-T water does not adversely affect slurries for the gasifier. There are a few cases where in fact the addition of F-T water caused favorable changes in viscosity of the slurries. This RD&T task was executed in Phase II and results are reported herein.

Abdalla H. Ali; Raj Kamarthi; John H. Anderson; Earl R. Berry; Charles H. Schrader; Lalit S. Shah

2003-04-16T23:59:59.000Z

139

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The 1999 U. S. Department of Energy (DOE) award to Texaco Energy Systems Inc. (presently Texaco Energy Systems LLC, a subsidiary of ChevronTexaco) was made to provide a Preliminary Engineering Design of an Early Entrance Coproduction Plant (EECP). Since the award presentation, work has been undertaken to achieve an economical concept design that makes strides toward the DOE Vision 21 goal. The objective of the EECP is to convert coal and/or petroleum coke to electric power plus transportation fuels, chemicals and useful utilities such as steam. The use of petroleum coke was added as a fuel to reduce the cost of feedstock and also to increase the probability of commercial implementation of the EECP concept. This objective has been pursued in a three phase effort through the partnership of the DOE with prime contractor Texaco Energy Systems LLC and subcontractors General Electric (GE), Praxair, and Kellogg Brown and Root (KBR). ChevronTexaco is providing gasification technology and Rentech's Fischer-Tropsch technology that has been developed for non-natural gas feed sources. GE is providing gas turbine technology for the combustion of low energy content gas. Praxair is providing air separation technology, and KBR is providing engineering to integrate the facility. The objective of Phase I was to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. Phase I Preliminary Concept Report was completed in 2000. The Phase I Preliminary Concept Report was prepared based on making assumptions for the basis of design for various technologies that are part of the EECP concept. The Phase I Preliminary Concept Report was approved by the DOE in May 2001. The Phase I work identified technical and economic risks and critical research, development, and testing that would improve the probability of the technical and economic success of the EECP. The Project Management Plan (Task 1) for Phase II was approved by the DOE in 2001. The results of RD&T efforts for Phase II are expected to improve the quality of assumptions made in Phase I for basis of design for the EECP concept. The RD&T work plan (Task 2 and 3) for Phase II has been completed. As the RD&T work conducted during Phase II concluded, it became evident that sufficient, but not necessarily complete, technical information and data would be available to begin Phase III - Basic Engineering Design. Also due to the merger of Chevron and Texaco, the proposed refinery site for the EECP was not available. It became apparent that some additional technical development work would be needed to correctly apply the technology at a specific site. The objective of Task 4 of Phase II is to update the concept basis of design produced during Phase I. As part of this task, items that will require design basis changes and are not site dependent have been identified. The team has qualitatively identified the efforts to incorporate the impacts of changes on EECP concept. The design basis has been modified to incorporate those changes. The design basis changes for those components of EECP that are site and feedstock dependent will be done as part of Phase III, once the site has been selected.

Charles Benham; Mark Bohn; John Anderson; Earl Berry; Fred Brent; Ming He; Randy Roberts; Lalit Shah; Marjan Roos

2003-09-15T23:59:59.000Z

140

Cost Analysis of an HIV/AIDS Prevention Project: A Case Study of the AIDS 3 Project in BENIN.  

E-Print Network [OSTI]

??HIV/AIDS Cost analysis The objective of this thesis is to undertake a cost analysis of an HIV/AIDS prevention programme targeting vulnerable groups in Benin. The (more)

Mito-Yobo, Kodjo Ferdinand

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Stigma trajectories among people living with HIV (PLHIV) embarking on a life time journey with antiretroviral drugs in Jinja, Uganda  

E-Print Network [OSTI]

therapy in Jinja, Uganda. Cult Health Sexuality 2011, 13(5):of HIV and AIDS in Rakai, Uganda. 19751990. Afr J AIDS Restested HIV negative in Uganda. Sociol Health Illn 2011, 36.

Mbonye, Martin; Nakamanya, Sarah; Birungi, Josephine; King, Rachel; Seeley, Janet; Jaffar, Shabbar

2013-01-01T23:59:59.000Z

142

AGING FACILITY WORKER DOSE ASSESSMENT  

SciTech Connect (OSTI)

The purpose of this calculation is to estimate radiation doses received by personnel working in the Aging Facility performing operations to transfer aging casks to the aging pads for thermal and logistical management, stage empty aging casks, and retrieve aging casks from the aging pads for further processing in other site facilities. Doses received by workers due to aging cask surveillance and maintenance operations are also included. The specific scope of work contained in this calculation covers both collective doses and individual worker group doses on an annual basis, and includes the contributions due to external and internal radiation from normal operation. There are no Category 1 event sequences associated with the Aging Facility (BSC 2004 [DIRS 167268], Section 7.2.1). The results of this calculation will be used to support the design of the Aging Facility and to provide occupational dose estimates for the License Application. The calculations contained in this document were developed by Environmental and Nuclear Engineering of the Design and Engineering Organization and are intended solely for the use of the Design and Engineering Organization in its work regarding facility operation. Yucca Mountain Project personnel from the Environmental and Nuclear Engineering should be consulted before use of the calculations for purposes other than those stated herein or use by individuals other than authorized personnel in Environmental and Nuclear Engineering.

R.L. Thacker

2005-03-24T23:59:59.000Z

143

Early lunar geology and geophysics  

E-Print Network [OSTI]

Despite a number of human and robotic missions to the Moon, there are still important unanswered questions about its early evolution, and how it came to be the object we observe today. Here we use observational, experimental, ...

Garrick-Bethell, Ian, 1980-

2009-01-01T23:59:59.000Z

144

Blind teen-age students' expectations Focus: school-age  

E-Print Network [OSTI]

Blind teen-age students' expectations Focus: school-age Topic: What are the changing demands disabled pupils, inclusion increased significantly, particularly in high schools. Blind learners, who used. For this lecture, I will present a few blind students' opinions, which will help building the items for the case

Paris-Sud XI, Universit de

145

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which produces at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. Each of the EECP subsystems were assessed for technical risks and barriers. A plan was identified to mitigate the identified risks (Phase II RD&T Plan, October 2000). The RD&T Plan identified petroleum coke characteristics as a potential technical risk. The composition of petroleum coke varies from one refinery to another. Petroleum coke characteristics are a function of the crude oil slate available at the refinery and the coker operating parameters. The specific petroleum coke characteristics at a refinery affect the design of the Gasification and Acid Gas Removal (AGR) subsystems. Knowing the petroleum coke composition provides the necessary data to proceed to the EECP Phase III engineering design of the gasification process. Based on ChevronTexaco's experience, the EECP team ranked the technical, economic, and overall risks of the petroleum coke composition related to the gasification subsystem as low. In Phase I of the EECP Project, the Motiva Port Arthur Refinery had been identified as the potential EECP site. As a result of the merger between Texaco and Chevron in October 2001, Texaco was required to sell its interest in the Motiva Enterprises LLC joint venture to Shell Oil Company and Saudi Refining Inc. To assess the possible impact of moving the proposed EECP host site to a ChevronTexaco refinery, samples of petroleum coke from two ChevronTexaco refineries were sent to MTC for bench-scale testing. The results of the analysis of these samples were compared to the Phase I EECP Gasification Design Basis developed for Motiva's Port Arthur Refinery. The analysis confirms that if the proposed EECP is moved to a new refinery site, the Phase I EECP Gasification Design Basis would have to be updated. The lower sulfur content of the two samples from the ChevronTexaco refineries indicates that if one of these sites were selected, the Sulfur Recovery Unit (SRU) might be sized smaller than the current EECP design. This would reduce the capital expense of the SRU. Additionally, both ChevronTexaco samples have a higher hydrogen to carbon monoxide ratio than the Motiva Port Arthur petroleum coke. The higher hydrogen to carbon monoxide ratio could give a slightly higher F-T products yield from the F-T Synthesis Reactor. However, the EECP Gasification Design Basis can not be updated until the site for the proposed EECP site is finalized. Until the site is finalized, the feedstock (petroleum coke) characteristics are a low risk to the EECP project.

Abdalla H. Ali; John H. Anderson; Earl R. Berry; Charles H. Schrader; Lalit S. Shah

2003-04-16T23:59:59.000Z

146

EARLY ENTRANCE COPRODUCTION PLANT  

SciTech Connect (OSTI)

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. Each of the EECP subsystems was assessed for technical risks and barriers. A plan was developed to mitigate the identified risks (Phase II RD&T Plan, October 2000). Phase II RD&T Task 2.6 identified as potential technical risks to the EECP the fuel/engine performance and emissions of the F-T diesel fuel products. Hydrotreating the neat F-T diesel product reduces potentially reactive olefins, oxygenates, and acids levels and alleviates corrosion and fuel stability concerns. Future coproduction plants can maximize valuable transportation diesel by hydrocracking the F-T Synthesis wax product to diesel and naphtha. The upgraded neat F-T diesel, hydrotreater F-T diesel, and hydrocracker F-T diesel products would be final blending components in transportation diesel fuel. Phase II RD&T Task 2.6 successfully carried out fuel lubricity property testing, fuel response to lubricity additives, and hot-start transient emission tests on a neat F-T diesel product, a hydrocracker F-T diesel product, a blend of hydrotreater and hydrocracker F-T diesel products, and a Tier II California Air Resources Board (CARB)-like diesel reference fuel. Only the neat F-T diesel passed lubricity inspection without additive while the remaining three fuel candidates passed with conventional additive treatment. Hot-start transient emission tests were conducted on the four fuels in accordance with the U.S. Environmental Protection Agency (EPA) Federal Test Procedure (FTP) specified in Code of Federal Regulations, Title 40, Part 86, and Subpart N on a rebuilt 1991 Detroit Diesel Corporation Series 60 heavy-duty diesel engine. Neat F-T diesel fuel reduced oxides of nitrogen (NO{sub x}), total particulate (PM), hydrocarbons (HC), carbon monoxide (CO), and the Soluble Organic Fraction (SOF) by 4.5%, 31%, 50%, 29%, and 35%, respectively, compared to the Tier II CARB-like diesel. The hydrocracker F-T diesel product and a blend of hydrocracker and hydrotreater F-T diesel products also reduced NO{sub x}, PM, HC, CO and SOF by 13%, 16% to 17%, 38% to 63%, 17% to 21% and 21% to 39% compared to the Tier II CARB-like diesel. The fuel/engine performance and emissions of the three F-T diesel fuels exceed the performance of a Tier II CARB-like diesel. Phase II RD&T Task 2.6 successfully met the lubricity property testing and F-T diesel fuel hot-start transient emissions test objectives. The results of the testing help mitigate potential economic risks on obtaining a premium price for the F-T diesel fuel

Fred D. Brent; Lalit Shah; Earl Berry; Charles H. Schrader; John Anderson; J. Erwin; Matthew G. Banks; Terry L. Ullman

2004-01-12T23:59:59.000Z

147

Age characteristics in a multidecadal Arctic sea ice simulation  

SciTech Connect (OSTI)

Results from adding a tracer for age of sea ice to a sophisticated sea ice model that is widely used for climate studies are presented. The consistent simulation of ice age, dynamics, and thermodynamics in the model shows explicitly that the loss of Arctic perennial ice has accelerated in the past three decades, as has been seen in satellite-derived observations. Our model shows that the September ice age average across the Northern Hemisphere varies from about 5 to 8 years, and the ice is much younger (about 2--3 years) in late winter because of the expansion of first-year ice. We find seasonal ice on average comprises about 5% of the total ice area in September, but as much as 1.34 x 10{sup 6} km{sup 2} survives in some years. Our simulated ice age in the late 1980s and early 1990s declined markedly in agreement with other studies. After this period of decline, the ice age began to recover, but in the final years of the simulation very little young ice remains after the melt season, a strong indication that the age of the pack will again decline in the future as older ice classes fail to be replenished. The Arctic ice pack has fluctuated between older and younger ice types over the past 30 years, while ice area, thickness, and volume all declined over the same period, with an apparent acceleration in the last decade.

Hunke, Elizabeth C [Los Alamos National Laboratory; Bitz, Cecllia M [UNIV. OF WASHINGTON

2008-01-01T23:59:59.000Z

148

J Bone Miner Res . Author manuscript Fracture risk prediction using BMD and clinical risk factors in early  

E-Print Network [OSTI]

,651 peri- and early post-menopausal women (mean age ( SD): 54 4 yr) with a mean follow-up period of 13 Density ; Female ; Fractures, Bone ; etiology ; Humans ; Middle Aged ; Osteoporosis, Postmenopausal definition of osteoporosis ( ), i.e. a bone mineral density (BMD) value less than 2.5 standard deviations

Paris-Sud XI, Universit de

149

HIV and Its Treatment Is My Treatment Regimen Working? Is My Treatment Regimen Working?  

E-Print Network [OSTI]

viral load, it's important to closely follow your treatment regimen. Poor treatment adherence can also blood tests to monitor your HIV treatment: CD4 count and viral load test. The results of the tests need a CD4 count only once every 6 to 12 months. What is a viral load test? Preventing HIV from

Levin, Judith G.

150

Universal Access to HIV Treatment versus Universal `Test and Treat': Transmission, Drug Resistance & Treatment  

E-Print Network [OSTI]

Universal Access to HIV Treatment versus Universal `Test and Treat': Transmission, Drug Resistance a universal `test and treat' (T&T) strategy to try to eliminate HIV in SA; treatment reduces infectivity in need or not. This would require treating 5 million individuals almost immediately and providing

Blower, Sally

151

Solid-State Nuclear Magnetic Resonance Measurements of HIV Fusion Peptide 13  

E-Print Network [OSTI]

Solid-State Nuclear Magnetic Resonance Measurements of HIV Fusion Peptide 13 CO to Lipid 31 P ABSTRACT: Fusion of the human immunodeficiency virus (HIV) membrane and the host cell membrane is an initial step of infection of the host cell. Fusion is catalyzed by gp41, which is an integral membrane

Weliky, David

152

Computational structure-based methods to anticipate HIV drug resistance evolution and accelerate inhibitor discovery  

E-Print Network [OSTI]

energy results from large-scale virtual screening identi?es representative wild-wild-type structure, speci?c amino acid substitutions are modeled, followed by energywild?type HIV?1 mutant HIV?2 Ligand Protease Figure 6.2: Speci?c energy

Chang, Max W.

2008-01-01T23:59:59.000Z

153

Single-Molecule Study of DNA Polymerization Activity of HIV-1 Reverse Transcriptase on DNA Templates  

E-Print Network [OSTI]

Single-Molecule Study of DNA Polymerization Activity of HIV-1 Reverse Transcriptase on DNA unwinding protein, such as a helicase. In order to understand the mechanism of polymerization through secondary structures, we investigated the DNA polymerization activity of HIV-1 RT on long ssDNA templates

Xie, Xiaoliang Sunney

154

Women Who Know: The Relationship Between Gender, Risk, Race, and HIV Testing  

E-Print Network [OSTI]

My main focus of interest in this dissertation is to evaluate the relationship between known risk factor for HIV and HIV testing behavior, with a particular interest in women. Utilizing data from the National Survey of Family Growth, I conduct both...

Howden, Lindsay M.

2010-07-14T23:59:59.000Z

155

AGING SYSTEM DESIGN DEVELOPMENT STRATEGY  

SciTech Connect (OSTI)

This plan provides an overview, work to date, and the path forward for the design development strategy of the Aging cask for aging commercial spent nuclear fuel (CSNF) at the Yucca Mountain Project (YMP) repository site. Waste for subsurface emplacement at the repository includes US Department of Energy (DOE) high-level radioactive waste (HLW), DOE SNF, commercial fuel in dual-purpose canisters (DPCs), uncanistered bare fuel, naval fuel, and other waste types. Table 1-1 lists the types of radioactive materials that may be aged at YMP, and those materials that will not be placed in an aging cask or module. This plan presents the strategy for design development of the Aging system. The Aging system will not handle naval fuel, DOE HLW, MCOs, or DOE SNF since those materials will be delivered to the repository in a state and sequence that allows them to be placed into waste packages for emplacement. Some CSNF from nuclear reactors, especially CSNF that is thermally too hot for emplacement underground, will need to be aged at the repository.

J. Beesley

2005-02-07T23:59:59.000Z

156

Cell Senescence: Aging and Cancer  

ScienceCinema (OSTI)

Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown how a natural process for fighting cancer in younger persons can actually promote cancer in older individuals.

Campisi, Judith

2013-05-29T23:59:59.000Z

157

Malcolm Guite Poets in Age  

E-Print Network [OSTI]

Malcolm Guite Poets in Age or A Study of Reading Habits At first I used to wish that I were Keats passing bell is rung. But now I need the poets who grew old And wore the bottoms of their trousers rolled of pure gold. I need the poets now, who match my age, Like Coleridge I could become a sage, And I bet I

Robertson, Stephen

158

Early English Books on microfilm  

E-Print Network [OSTI]

search term in one box, or two if you are combining or excluding terms. You can leave the Search Three. In the next search box, enter the words early english books. Leave the other defaults alone. Now access the catalog (libcat.wichita.edu), change the default to Advanced Search: Step Two. Place your

159

Visualising Early Product Development Information  

E-Print Network [OSTI]

screws store energy Electricity Supply Screw User Force couple screw & PSD Installed Screw Waste Energy System Bit Bit Screw Screw Electricity Supply Waste Energy User Force Activation System User Input Architecture Systems Design Design Schematics for visualisation of early product information Light

Salustri, Filippo A.

160

Equal Access Initiative HIV/AIDS Information Resources from NLM  

SciTech Connect (OSTI)

The Equal Access Initiative: HIV/AIDS Information Resources from the National Library of Medicine training is designed specifically for the National Minority AIDS Council 2010 Equal Access Initiative (EAI) Computer Grants Program awardees to provide valuable health information resources from the National Library of Medicine and other reliable sources to increase awareness of the wealth of treatment information and educational materials that are available on the Internet and to improve prevention and treatment education for their clients. These resources will also meet the needs of community-based

Templin-Branner W. and N. Dancy

2010-09-11T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

HIV immunity study could pave way for vaccine development  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuided Self-Assembly of GoldHAWCHIGS flux performanceHIV

162

New global HIV vaccine design shows promise in monkeys  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas Conchas recoveryLaboratory | NationalJohn CyberNeutrons usedDOENewNewNew global HIV vaccine

163

THE AGE OF PLASTIC INGENUITY + RESPONSIBILITY  

E-Print Network [OSTI]

THE AGE OF PLASTIC INGENUITY + RESPONSIBILITY An Interdisciplinary Symposium Stone Age, Bronze Age, Iron Age...and now the Age of Plastic. The Smithsonian Institution is leveraging its collections--arguably the world's greatest repository of plastic material culture--to investigate the significance of plastic, its

Mathis, Wayne N.

164

A review of "Early Modern French Thought: The Age of Suspicion." by Michael Moriarty  

E-Print Network [OSTI]

?oise Lavocat. La Syrinx au b?cher. Pan et les satyres ? la Renaissance et ? l??ge baroque. Geneva: Droz, 2005. 536 pp. + 62 illus. CHF 140.00. Review by FRAN?OIS RIGOLOT, PRINCETON UNIVERSITY. This is a well-researched and amply documented book...

Todd Janke

2006-01-01T23:59:59.000Z

165

Timing of the Early Triassic carbon cycle perturbations inferred from new UPb ages and ammonoid biochronozones  

E-Print Network [OSTI]

and Mineral Resources, Jiangzheng Road 1, 530023 Nanning, China Received 13 October 2006; received in revised significance for global correlations and for carbon cycle modeling. This calibration indicates that the most

Gilli, Adrian

166

EARLY-AGE CONCRETE STRENGTH ESTIMATION TECHNIQUE USING EMBEDDED PIEZOELECTRIC SELF-SENSING IMPEDANCE  

E-Print Network [OSTI]

-746 shparkpc@skku.edu ABSTRACT Recently, demands for the construction of Nuclear Power Plants (NPP) using high strength concrete (HSC) with a low W/C ratio and high compressive strength for construction NPP structures if the curing process is inadequate. To prevent unexpected collapse during and after the construction of HSC

Paris-Sud XI, Université de

167

Defining "Foreignness" in the Early Iron Age Mediterranean Program (subject to revision)  

E-Print Network [OSTI]

, and Administrator and Editor, Melammu Project Website and Database 2:40 Persis Berlekamp, Department of Art History Department of Art History and Humanities Institute, Northwestern University 9:35 Catherine Saint of Tartessos #12;12:15-2:00 Lunch 2:00 Johannes Haubold, Classics and Ancient History, Durham University 2

Shahriar, Selim

168

Modeling the Effect of Curing on Early Age Distress Potential of Concrete Pavement  

E-Print Network [OSTI]

in concrete structure. The results indicated that the constructability index was able to capture and demonstrate the effect of different parameters mentioned above on the constructability of rigid pavement/overlay projects....

Bari, Muhammad Ehsanul

2014-04-11T23:59:59.000Z

169

Guang Ye, Characterization of cement paste at early age, 1 of 11 Fax: +31 15 2785895  

E-Print Network [OSTI]

with the progress of the hydration process. The physical properties of concrete can be detected by, for example the speed of an ultrasonic pulse propagating through the concrete [1-6]. Researchers have shown [8] According to Bergman and Kantor [9] the stiffness of a porous material can be expressed

170

Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and  

E-Print Network [OSTI]

in parallel to the decline in glucose transport suggesting lactate did not serve as an alternative fuel as an alternative fuel. In the 3xTgAD brain, utilization of ketone bodies as an alternative fuel was evident in mitochondrial function. The adaptive shift to the ketogenic system as an alternative fuel coincided with decline

Brinton, Roberta Diaz

171

Mechanisms of Mating-Behavior Deterioration in Early Aging Male C. elegans  

E-Print Network [OSTI]

into their hermaphrodite mates. Through Ca^(2+) imaging, I found that the genital sex muscles are hyper-contracted during sperm transfer. This hyper-contraction blocks the vas deferens and obstructs sperm release. Furthermore, through qPCR, measurements of metabolites...

Guo, Xiaoyan

2014-08-06T23:59:59.000Z

172

Concrete Plant International (2008) REACT: Reducing Early-Age Cracking Today  

E-Print Network [OSTI]

construction. As is usually the case, the truth likely lies between these two extremes, perhaps humidity, wind speed, and concrete temperature to the evaporation rate from a water surface. Recently

Bentz, Dale P.

173

Houses for early weaned piglets : influence of rearing on the floor or in batteries,  

E-Print Network [OSTI]

Houses for early weaned piglets : influence of rearing on the floor or in batteries, temperature groups in order to determine the influence of rearing conditions (housing, room temperature) and feeding on the animals performances between weaning at 36 3 days and 70 days of age. Housing characteristics were

Paris-Sud XI, Universit de

174

Detrital geochronology and geochemistry of CretaceousEarly Miocene strata of Nepal: implications for timing and  

E-Print Network [OSTI]

Detrital geochronology and geochemistry of Cretaceous­Early Miocene strata of Nepal: implications of the southern Lesser Himalayan zone of central Nepal. The Cretaceous­ Paleocene(?) Amile Formation is dominated documented by the U­Pb zircon ages. The fact that middle Eocene strata in Nepal were derived from

Najman, Yani

175

MAGNETOSTRATIGRAPHY OF THE EARLY CRETACEOUS WEALDEN GROUP, ISLE OF WIGHT Conall Mac Niocaill, & Stephen Hesselbo  

E-Print Network [OSTI]

available database. The goal of this project is to obtain high-precision estimates of the intensity wetlands and have recently yielded important data on Early Cretaceous atmospheric carbon dioxide content and carbon-isotopic composition. Being non-marine, however, the age of the succession is imprecisely known

Niocaill, Conall Mac

176

Multipath Probabilistic Early Response TCP  

E-Print Network [OSTI]

: Chair of Committee, A. L. Narasimha Reddy Committee Members, Riccardo Bettati Srinivas Shakottai Head of Department, Costas N. Georghiades August 2012 Major Subject: Computer Engineering iii ABSTRACT Multipath Probabilistic Early Response TCP.... (August 2012) Ankit Singh, B.Tech., Indian Institute of Technology, Guwahati Chair of Advisory Committee: Dr. A. L. Narasimha Reddy Many computers and devices such as smart phones, laptops and tablet devices are now equipped with multiple network...

Singh, Ankit

2012-10-19T23:59:59.000Z

177

Early Exercise Option Valuation 00000001111111  

E-Print Network [OSTI]

Early Exercise Option Valuation 0 0 1 1 00000001111111 s T 0 0s K Mm+1m t 0 With V (tM , S(tM)) = E. Computational Finance (Summerschool) Hitotsubashi University August 2009 2 / 51 #12;The CONV method (Carr-Madan extended) The main premise of the CONV method is that f (y|x) depends on x and y via f (y|x) = f (y - x

Oosterlee, Cornelis W. "Kees"

178

Deactivation of Accelerated Engine-Aged and Field-Aged SCR Catalysts...  

Broader source: Energy.gov (indexed) [DOE]

Deactivation of Accelerated Engine-Aged and Field-Aged SCR Catalysts and the Role of the DOC Deactivation of Accelerated Engine-Aged and Field-Aged SCR Catalysts and the Role of...

179

Transportation, Aging and Disposal Canister System Performance...  

Office of Environmental Management (EM)

specifications for selected system components of the Transportation, Aging and Disposal (TAD) canister-based system. Transportation, Aging and Disposal Canister System Performance...

180

Cross gender-age trabecular texture analysis in cone beam computed tomography  

E-Print Network [OSTI]

osteoporosis screening tools in the jaws. Keywords: cone-beam computed tomography, osteoporosis, radiology, osteoporosis afflicts 55% of Americans aged 50 and above.1 Early diagnosis of osteoporosis is very important to prevent more serious complications such as hip fracture. The current gold standard for osteoporosis

Ling, Haibin

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

WHOLE-ROCK 87Sr/86Sr COMPOSITION AND APPARENT STRONTIUM ISOTOPIC AGE OF LIMESTONES FROM SITE 1118, WOODLARK RIFT BASIN, SOUTHWEST PACIFIC (OCEAN DRILLING PROGRAM LEG 180)  

E-Print Network [OSTI]

Limestone from Unit VI (857.1859.15 meters below seafloor) collected at Site 1118 contains a planktonic foraminiferal fauna indicating a latest Miocene to early Pliocene age. Globorotalia tumida is recorded in Sample ...

Allan, Tony; Robertson, Alastair H F; Sharp, Timothy R; Trotter, Julie

2001-01-01T23:59:59.000Z

182

!anspace age esa SP-1150  

E-Print Network [OSTI]

.2 Solar Wind 3.3 Role of Europe 3.4 Conclusions and Recommendations 4. High-Energy Physics 4.8 Role of Europe 5.9 Conclusions and Recommendations 6. Exploitation of the Moon 6.1 Power Generation!anspace age #12;esa SP-1150 June 1992 MISSIONto the MOON Europe's Priorities

Rathbun, Julie A.

183

Kentucky Cheese: Coming of Age  

E-Print Network [OSTI]

i The FoodIssue Kentucky Cheese: Coming of Age pg. 7 Kentucky is Apple-icious A Taste for Success and does not imply approval to the exclusion of other suitable products or firms. Kentucky Cheese: Coming, and approved by UK's Food Systems Innovation Center. Kentucky is Apple-icious Let those northern and western

Hayes, Jane E.

184

Aging, tumor suppression and cancer: High-wire act!  

SciTech Connect (OSTI)

Evolutionary theory holds that aging is a consequence of the declining force of natural selection with age. We discuss here the evidence that among the causes of aging in complex multicellular organisms, such as mammals, is the antagonistically pleiotropic effects of the cellular responses that protect the organism from cancer. Cancer is relatively rare in young mammals, owing in large measure to the activity of tumor suppressor mechanisms. These mechanisms either protect the genome from damage and/or mutations, or they elicit cellular responses--apoptosis or senescence--that eliminate or prevent the proliferation of somatic cells at risk for neoplastic transformation.We focus here on the senescence response, reviewing its causes, regulation and effects. In addition, we describe recent data that support the idea that both senescence and apoptosis may indeed be the double-edged swords predicted by the evolutionary hypothesis of antagonistic pleiotropy--protecting organisms from cancer early in life, but promoting aging phenotypes, including late life cancer, in older organisms.

Campisi, Judith

2004-08-15T23:59:59.000Z

185

Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission  

E-Print Network [OSTI]

Vaccination and the application of a vaginal microbicide have traditionally been considered independent methods to prevent the sexual transmission of HIV-1 to women. Both techniques can be effective in macaque models, and ...

Klasse, Per Johan

186

E-Print Network 3.0 - antiretroviral-treated hiv-infected patients...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

by carotid intima-media thickness in patients with HIV infection. Circulation 2004; 109:1603-8. 10. Lebech AM... . Jerico C, Knobel H, Calvo N et al. Subclinical carotid ......

187

Regulatory T Cells Expanded from Hiv-1-Infected Individuals Maintain Phenotype, Tcr Repertoire and Suppressive Capacity  

E-Print Network [OSTI]

While modulation of regulatory T cell (Treg) function and adoptive Treg transfer are being explored as therapeutic modalities in the context of autoimmune diseases, transplantation and cancer, their role in HIV-1 pathogenesis ...

Angin, Mathieu

188

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys  

E-Print Network [OSTI]

Human immunodeficiency virus type 1 (HIV-1)-specific monoclonal antibodies with extraordinary potency and breadth have recently been described. In humanized mice, combinations of monoclonal antibodies have been shown to ...

Barouch, Dan H.

189

Engineering of HIV gp120 by yeast surface display for neutralizing antibody characterization and immunogen design  

E-Print Network [OSTI]

The sequence diversity of glycoprotein gp120 of the envelope spike of Human Immunodeficiency Virus (HIV) allows the virus to escape from antibody selection pressure. Certain conserved epitopes, like the CD4 binding site, ...

Mata-Fink, Jordi

2013-01-01T23:59:59.000Z

190

E-Print Network 3.0 - apobec3g drives hiv-1 Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Adaptive Evolution of the Primate Antiviral DNA-Editing Summary: , Schrofelbauer B, Navarro F, Konig R, et al. (2003) Species- specific exclusion of APOBEC3G from HIV-1...

191

E-Print Network 3.0 - anti-hiv-1 hammerhead ribozyme Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

hammerhead ribozyme Search Powered by Explorit Topic List Advanced Search Sample search results for: anti-hiv-1 hammerhead ribozyme Page: << < 1 2 3 4 5 > >> 1 Structure and...

192

E-Print Network 3.0 - acquired paediatric hiv Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

: (5 ) 1620 - 1626 Gaillard P... on prevention of mother-to-child HIV-1 transmission in Dar Es Salaam, Tanzania . JAIDS. Journal of Acquired... Soc Sci Med . Author manuscript...

193

Economic growth, convergence and the HIV/AIDS epidemic: a cross-country panel data analysis  

E-Print Network [OSTI]

This thesis presents an analysis of the dynamic process of economic growth, national welfare and the HIV/AIDS epidemic. An assessment of the methodological designs of applied growth research is undertaken in order to ...

Smith, Joel Benjamin Edmund

2011-07-05T23:59:59.000Z

194

E-Print Network 3.0 - acquired hiv infection Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Abidjan, Cte d'Ivoire 1997-2005 Summary: factors for incident HIV infection in rural Uganda. J Acquir Immune Defic Syndr 2000;23:418-25. 14... : minga.albert@yahoo.fr e-mail 2 :...

195

58 International Family Planning Perspectives The number of HIV infections in central and eastern Eu-  

E-Print Network [OSTI]

29.11 Unfortunately, little research exists on the sexu- al risk-taking behavior of Croatian young people. A 1989 of sexual behaviors and HIV/AIDS-related knowl- edge and attitudes among Croatian young adults. Using data

196

Efficient on-chip isolation of HIV subtypes ShuQi Wang,a  

E-Print Network [OSTI]

are living with HIV-1 worldwide, with Sub- Saharan Africa accounting for 67% of the infected population.1 on the microchannel surface with an elevated antibody density and uniform antibody orientation using a Protein G

Demirci, Utkan

197

Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins  

DOE Patents [OSTI]

The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.

Haynes, Barton F. (Durham, NC); Gao, Feng (Durham, NC); Korber, Bette T. (Los Alamos, NM); Hahn, Beatrice H. (Birmingham, AL); Shaw, George M. (Birmingham, AL); Kothe, Denise (Birmingham, AL); Li, Ying Ying (Hoover, AL); Decker, Julie (Alabaster, AL); Liao, Hua-Xin (Chapel Hill, NC)

2011-12-06T23:59:59.000Z

198

AEO2014 Early Release Overview  

Gasoline and Diesel Fuel Update (EIA)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) " ,"Click worksheet9,1,50022,3,,,,6,1,,781Title: Telephone:short version)ecTotalnerr g0@3 Early Release

199

LANL exceeds Early Recovery Act  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFunInfraredJeffersonJonathanMultimaterial2 J.N. Shadid,aSecurityexceeds Early

200

Miller wins Early Career Award  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: VegetationEquipment SurfacesResource Program PreliminaryA3, 1999ofMikeAdministrationMiller wins Early

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Early Edison Users Deliver Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series toESnet4: Networking for the Future of DOE ScienceEarly Edison Users

202

CASL OLCF Early Science Award  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed New Substation Sites Proposed Route Segments (notCAMDL2 Milestone VRI.P7.01OLCF Early

203

Miller wins Early Career Award  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas Conchas recovery challenge fundProject8 -3Eutectic CompositesMikeSpouseMiller wins Early

204

June 17, 2013 Symposium on Aging  

E-Print Network [OSTI]

to forestall and treat diseases of aging such as diabetes, cancer, Alzheimer's and heart disease. Today

Church, George M.

205

Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda  

E-Print Network [OSTI]

with HIV Initiating ART in Uganda Judith A. Hahn Mwebesaantiretroviral therapy in Uganda. Almost seven percent (persons initi- ating ART in Uganda. J. A. Hahn (&) J. N.

Hahn, Judith A.; Bwana, Mwebesa B.; Javors, Martin A.; Martin, Jeffrey N.; Emenyonu, Nneka I.; Bangsberg, David R.

2010-01-01T23:59:59.000Z

206

advancing paternal age: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

In most animals, advancing age is accompanied by the deteriorative process of aging (senescence). Aging is the main cause of severe illness and death in humans aging is...

207

advanced paternal age: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

In most animals, advancing age is accompanied by the deteriorative process of aging (senescence). Aging is the main cause of severe illness and death in humans aging is...

208

Chelation: A Fundamental Mechanism of Action of AGE Inhibitors...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications. Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE...

209

A Design Guide for Early-Market Electrochromic Windows  

E-Print Network [OSTI]

Guide for Early-Market Electrochromic Windows. CaliforniaGuide for Early-Market Electrochromic Windows. CaliforniaGUIDE FOR EARLY-MARKET ELECTROCHROMIC WINDOWS Prepared For:

2006-01-01T23:59:59.000Z

210

Hickam Air Force Base Fuel Cell Vehicles: Early Implementation...  

Broader source: Energy.gov (indexed) [DOE]

Hickam Air Force Base Fuel Cell Vehicles: Early Implementation Experience Hickam Air Force Base Fuel Cell Vehicles: Early Implementation Experience This report sumarizes early...

211

Nanostructured Optical Photonic Crystal Biosensor for HIV Viral Load Measurement  

E-Print Network [OSTI]

Detecting and quantifying biomarkers and viruses in biological samples have broad applications in early disease diagnosis and treatment monitoring. We have demonstrated a label-free optical sensing mechanism using ...

Shafiee, Hadi

212

The effect of Abstinence, Being faithful to one partner, and Condom use (ABC) messages on HIV infection among youth in Uganda  

E-Print Network [OSTI]

of Health (MOH) [Uganda] and ORC Macro Uganda HIV/AIDS Sero-USA: Ministry of Health and ORC Macro, 2006. 7. Harrison A,of Health (MOH) [Uganda] and ORC Macro Uganda HIV/AIDS Sero-

Ekwaru, John Paul

2012-01-01T23:59:59.000Z

213

The effect of Abstinence, Being faithful to one partner, and Condom use (ABC) messages on HIV infection among youth in Uganda  

E-Print Network [OSTI]

intervention on HIV incidence in Masaka, Uganda. AIDSpopulation-based cohort, Uganda. AIDS 1998;12:226-8. 10.HIV/AIDS prevention in Uganda: why has it worked? Postgrad

Ekwaru, John Paul

2012-01-01T23:59:59.000Z

214

Side effects : the new age of AIDS in America  

E-Print Network [OSTI]

When the cocktail of AIDS drugs called highly active antiretroviral therapy (HAART) was introduced in 1997, it radically changed the picture of HIV and AIDS in the U.S. Deaths from AIDS plummeted by two-thirds. Now, far ...

Humphries, Courtney (Courtney Elizabeth)

2004-01-01T23:59:59.000Z

215

EARLY EVOLUTION OF PRESTELLAR CORES  

SciTech Connect (OSTI)

Prestellar cores are approximated by singular polytropic spheres. Their early evolution is studied analytically with a Bondi-like scheme. The considered approximation is meaningful for polytropic exponents {gamma} between 0 and 6/5, implying radial power-law density profiles between r {sup -1} and r {sup -2.5}. Gravitationally unstable Jeans and Bonnor-Ebert masses differ at most by a factor of 3.25. Tidally stable prestellar cores must have a mean density contrast {approx}> 8 with respect to the external parent cloud medium. The mass-accretion rate relates to the cube of equivalent sound speed, as in Shu's seminal paper. The prestellar masses accreted over 10{sup 5} years cover the whole stellar mass spectrum; they are derived in simple closed form, depending only on the polytropic equation of state. The stellar masses that can be formed via strict conservation of angular momentum are at most of the order of a brown dwarf.

Horedt, G. P., E-mail: g.horedt@online.de [Kronwinkler 50, D-81245, Munich (Germany)

2013-08-20T23:59:59.000Z

216

Aging of Pentaerythritol Tetranitrate (PETN)  

SciTech Connect (OSTI)

Pentaerythritol tetranitrate (PETN) is a relatively sensitive explosive used in many electroexplosive devices as well as in medicine. Of primary interest to LLNL is its use in items such as exploding bridgewire (EBW) detonators and exploding bridge foil initiators (EFI). In these devices the crystalline powder is pressed into a granular, low-density compact that can be initiated by an exploding wire or foil. The long-term stability of this pressed compact is of interest to weapon stockpile lifetime prediction studies. Key points about potential aging mechanisms can be summarized as follows: (1) There are a number of factors that can contribute to PETN instability. These include particle size, polymorphic phase transitions, crystal structure, impurities, moisture, occlusions, chemical incompatibility and biological (microorganism) action. of these factors the most important for long-term aging of high surface area powders used in detonators appears to be that of particle size growth. (2) There is a great deal of literature on the thermal degradation kinetics of PETN, unfortunately much of it with little bearing on ambient temperature aging during long-term storage. PETN is very stable with respect to thermal decomposition. Low-temperature thermal studies have not revealed evidence of chemical degradation products in archived PETN. Data extrapolated to 30 C predicts a half-life of 12 million years. (3) Moisture seems to lower the activation energy for and accelerate the decomposition of PETN. (4) External drivers affecting stability include temperature, moisture, radiation fields, and stress, while internal drivers include residual solvents, and impurities. Temperature affects kinetic processes of crystal growth such as adsorption, desorption, and diffusion rates of molecules on the surface of PETN crystals. A low-level radiation field may induce unexpected changes in the chemical makeup of PETN and its homologue impurities. Stress at high pressure points caused by crystalline surface irregularities may cause a decrease in surface area over time due to smoothing of contact points and sintering. PETN has been found to contain a number of impurities, including homologues, pentaerythryl ethers with a mixture of hydroxyl and nitrate functional groups, and organic salts, that can alter its physical and chemical properties. (5) The processes of sublimation/recrystallization and surface diffusion are important processes that can cause changes in PETN crystal morphology, particle size distribution and specific surface area. Sublimation feeds a process called Ostwald ripening, which involves the spontaneous growth of larger crystals from those of smaller size. This process proceeds with age regardless of storage conditions unless the crystals are treated to retard growth. The coarsening mechanisms include Ostwald ripening, 'sintering', and surface diffusion. The latter has not been experimentally observed, but a molecular modeling approach has attempted to investigate this phenomenon theoretically. (6) Threshold test fire, particle size distribution, specific surface area, thermal analysis, chemical analysis, powder compact specific surface area and density are approaches that have been used in the attempt to assess changes attributable to aging of PETN, with varying results. The biggest problem lies in the aging mechanism itself, which likely influences small changes in morphology, both internal and external, and particle size distribution changes on a scale too small to reliably monitor. Other aspects, such as subtle changes in density profiles within pressed powder compacts, may be beyond the capability of current technology to assess. Crystal growth significant enough to affect the PETN particle size distribution is expected to impact detonator performance. (7) Factors relevant to stabilizing particle size growth include crystal morphology, powder surface area and particle size distribution; crystal density and internal defects; and powder compact density and density gradients.

Foltz, M F

2009-04-22T23:59:59.000Z

217

SNF AGING SYSTEM DESCRIPTION DOCUMENT  

SciTech Connect (OSTI)

The purpose of this system description document (SDD) is to establish requirements that drive the design of the spent nuclear fuel (SNF) aging system and associated bases, which will allow the design effort to proceed. This SDD will be revised at strategic points as the design matures. This SDD identifies the requirements and describes the system design, as it currently exists, with emphasis on attributes of the design provided to meet the requirements. This SDD is an engineering tool for design control; accordingly, the primary audience and users are design engineers. This SDD is part of an iterative design process. It leads the design process with regard to the flow down of upper tier requirements onto the system. Knowledge of these requirements is essential in performing the design process. The SDD follows the design with regard to the description of the system. The description provided in the SDD reflects the current results of the design process. Throughout this SDD, the term aging cask applies to vertical site-specific casks and to horizontal aging modules. The term overpack is a vertical site-specific cask that contains a dual-purpose canister (DPC) or a disposable canister. Functional and operational requirements applicable to this system were obtained from ''Project Functional and Operational Requirements'' (F&OR) (Curry 2004 [DIRS 170557]). Other requirements that support the design process were taken from documents such as ''Project Design Criteria Document'' (PDC) (BSC 2004 [DES 171599]), ''Site Fire Hazards Analyses'' (BSC 2005 [DIRS 172174]), and ''Nuclear Safety Design Bases for License Application'' (BSC 2005 [DIRS 171512]). The documents address requirements in the ''Project Requirements Document'' (PRD) (Canori and Leitner 2003 [DIRS 166275]). This SDD includes several appendices. Appendix A is a Glossary; Appendix B is a list of key system charts, diagrams, drawings, lists and additional supporting information; and Appendix C is a list of procedures that will be used to operate the system.

L.L. Swanson

2005-04-06T23:59:59.000Z

218

High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function  

E-Print Network [OSTI]

The dissemination of HIV from an initial site of infection is facilitated by motile HIV-infected CD4+ T-cells. However, the impact of infected target cell migration on antigen recognition by HIV-specific CD8+ T-cells is ...

Foley, Maria Hottelet

219

Solid-State Nuclear Magnetic Resonance Measurements of HIV Fusion Peptide to Lipid Distances Reveal the Intimate Contact of Strand Peptide with Membranes  

E-Print Network [OSTI]

Solid-State Nuclear Magnetic Resonance Measurements of HIV Fusion Peptide to Lipid Distances Reveal 23, 2007 ABSTRACT: Human immunodeficiency virus (HIV) infection begins with fusion between viral and host cell membranes and is catalyzed by the HIV gp41 fusion protein. The 20 N-terminal apolar residues

Weliky, David

220

Safety of Autologous, Ex Vivo-Expanded Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Infusion in HIV-Infected Patients  

E-Print Network [OSTI]

-Lymphocyte Infusion in HIV-Infected Patients By Judy Lieberman, Paul R. Skolnik, G. Robert Parkerson III, Jessica A. Fabry, Bernard Landry, James Bethel, Jonathan Kagan, and the DATRI 006 Study Team We infused six human after the infusion suggests that antiviral CTLs of diverse specificities do not play a significant role

Lieberman, Judy

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Early dynamics of transversally thermalized matter  

E-Print Network [OSTI]

We argue that the idea that the parton system created in relativistic heavy-ion collisions is formed in a state with transverse momenta close to thermodynamic equilibrium and its subsequent dynamics at early times is dominated by pure transverse hydrodynamics of the perfect fluid is compatible with the data collected at RHIC. This scenario of early parton dynamics may help to solve the problem of early equilibration.

A. Bialas; M. Chojnacki; W. Florkowski

2008-04-28T23:59:59.000Z

222

Dark Energy in the Dark Ages  

E-Print Network [OSTI]

LBNL- 61876 Dark Energy in the Dark Ages Eric V. LinderUniversity of California. Dark Energy in the Dark Ages Eric2008) Non-negligible dark energy density at high redshifts

Linder, Eric V.

2009-01-01T23:59:59.000Z

223

Utah Commission on Aging June 6, 2007  

E-Print Network [OSTI]

Institutions Norma Matheson Chair Anne Peterson University of Utah Mayor JoAnn Seghini Midvale City Sara to the Commission for consideration. Aging SMART: Denise Brooks distributed Aging SMART Sourcebook. Website is up

Tipple, Brett

224

Atlas of Chiefdoms and Early States  

E-Print Network [OSTI]

file published with the Atlas has variable names and valuein subsequent editions of this Atlas the simple dichotomythe title suggests, this is an atlas of chiefdoms and early

Wright, Henry T.

2006-01-01T23:59:59.000Z

225

Dry aging beef for the retail channel  

E-Print Network [OSTI]

Koohmaraie, & Goll, 1995). The Z-line is one myofibrillar structure clearly altered by proteases in the postmortem aging of beef (Goll, Otsuka, Nagainis, Shannon, Sathe, & Muguruma, 1983). However, Z-disk degradation does not occur to any significant... and humidity is said to be dry aged. Practically all beef is vacuumed packaged at the packer level. However, many believe 3 that wet aging does not produce the enhanced palatability characteristics associated with dry aged beef. This process can...

Smith, Robert David

2007-09-17T23:59:59.000Z

226

Library versus Library Recognition and Inhibition of the HIV-1 Nef Allelome Allison Olszewski and Gregory A. Weiss*,,  

E-Print Network [OSTI]

Library versus Library Recognition and Inhibition of the HIV-1 Nef Allelome Allison Olszewski resistance. Targeting HIV Nef with small molecules screened against a combinatorial library of Nef variants studies. We asked whether a library versus library approach could simultaneously uncover structure

Weiss, Gregory A.

227

A fluid approach to HIV A readable anthropological account of social networks in South Africa and Uganda explains differences in  

E-Print Network [OSTI]

and Uganda explains differences in the spread of sexually transmitted diseases in those countries, finds, but it was a "ritualistic act of cleansing and strengthening", says Thornton. Uganda's HIV story offers a more pleasant in its fight against the virus. Uganda reduced HIV prevalence by two- thirds during the 1990s. Causes

Cai, Long

228

Effectiveness of a sports-based HIV prevention intervention in the Dominican Republic: a quasi-experimental study  

E-Print Network [OSTI]

Effectiveness of a sports-based HIV prevention intervention in the Dominican Republic: a quasi, and strenuous efforts to minimize loss-to-follow-up. Keywords: HIV; youth; sport; Dominican Republic; Caribbean living in Haiti and the Dominican Republic (DR) (PAHO, 2007; UNAIDS, 2008). In recent years, national

Vermont, University of

229

Prophylactic antiretroviral regimens for prevention of mother-to-child transmission of HIV in resource-limited settings  

E-Print Network [OSTI]

in resource-limited settings Arrive Elise * , Dabis Francois Epidemiologie, sante publique et developpement international mobilization against HIV/AIDS, more HIV-infected people in resource-limited settings have access ; Resource-limited settings ; Prophylactic antiretroviral regimens ; Single-dose nevirapine ; Breastfeeding

Paris-Sud XI, Université de

230

Expanded breadth of the T-cell response to mosaic HIV-1 envelope DNA vaccination  

SciTech Connect (OSTI)

An effective AIDS vaccine must control highly diverse circulating strains of HIV-1. Among HIV -I gene products, the envelope (Env) protein contains variable as well as conserved regions. In this report, an informatic approach to the design of T-cell vaccines directed to HIV -I Env M group global sequences was tested. Synthetic Env antigens were designed to express mosaics that maximize the inclusion of common potential Tcell epitope (PTE) 9-mers and minimize the inclusion of rare epitopes likely to elicit strain-specific responses. DNA vaccines were evaluated using intracellular cytokine staining (ICS) in inbred mice with a standardized panel of highly conserved 15-mer PTE peptides. I, 2 and 3 mosaic sets were developed that increased theoretical epitope coverage. The breadth and magnitude ofT-cell immunity stimulated by these vaccines were compared to natural strain Env's; additional comparisons were performed on mutant Env's, including gpl60 or gpl45 with or without V regions and gp41 deletions. Among them, the 2 or 3 mosaic Env sets elicited the optimal CD4 and CD8 responses. These responses were most evident in CD8 T cells; the 3 mosaic set elicited responses to an average of 8 peptide pools compared to 2 pools for a set of3 natural Env's. Synthetic mosaic HIV -I antigens can therefore induce T-cell responses with expanded breadth and may facilitate the development of effective T -cell-based HIV -1 vaccines.

Korber, Bette [Los Alamos National Laboratory; Fischer, William [Los Alamos National Laboratory; Wallstrom, Timothy [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

231

Identification of a D-amino acid decapeptide HIV-1 entry inhibitor  

SciTech Connect (OSTI)

Entry of human immunodeficiency virus type 1 (HIV-1) virion into host cells involves three major steps, each being a potential target for the development of entry inhibitors: gp120 binding to CD4, gp120-CD4 complex interacting with a coreceptor, and gp41 refolding to form a six-helix bundle. Using a D-amino acid decapeptide combinatorial library, we identified peptide DC13 as having potent HIV-1 fusion inhibitory activity, and effectively inhibiting infection by several laboratory-adapted and primary HIV-1 strains. While DC13 did not block binding of gp120 to CD4, nor disrupt the gp41 six-helix bundle formation, it effectively blocked the binding of an anti-CXCR4 monoclonal antibody and chemokine SDF-1{alpha} to CXCR4-expressing cells. However, because R5-using primary viruses were also neutralized, the antiviral activity of DC13 implies additional mode(s) of action. These results suggest that DC13 is a useful HIV-1 coreceptor antagonist for CXCR4 and, due to its biostability and simplicity, may be of value for developing a new class of HIV-1 entry inhibitors.

Boggiano, Cesar [Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121 (United States); Jiang Shibo [Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10021 (United States); Lu Hong [Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10021 (United States); Zhao Qian [Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10021 (United States); Liu Shuwen [Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10021 (United States); Binley, James [Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121 (United States); Blondelle, Sylvie E. [Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121 (United States)]. E-mail: sylvieb@burnham.org

2006-09-08T23:59:59.000Z

232

aged rat erectile: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

98504-3144 An age-length key (ALK) is the tra- ditional method for estimating age-stage length samples for relatively costly age determination (age subsamplel. Age...

233

aged interleukin-18 deficient: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

98504-3144 An age-length key (ALK) is the tra- ditional method for estimating age-stage length samples for relatively costly age determination (age subsamplel. Age...

234

age stratigraphic relationships: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

98504-3144 An age-length key (ALK) is the tra- ditional method for estimating age-stage length samples for relatively costly age determination (age subsamplel. Age...

235

Noncommutativity in the early Universe  

E-Print Network [OSTI]

In the present work, we study the noncommutative version of a quantum cosmology model. The model has a Friedmann-Robertson-Walker geometry, the matter content is a radiative perfect fluid and the spatial sections have zero constant curvature. In this model the scale factor takes values in a bounded domain. Therefore, its quantum mechanical version has a discrete energy spectrum. We compute the discrete energy spectrum and the corresponding eigenfunctions. The energies depend on a noncommutative parameter $\\beta$. We compute the scale factor expected value ($\\left$) for several values of $\\beta$. For all of them, $\\left$ oscillates between maxima and minima values and never vanishes. It gives an initial indication that those models are free from singularities, at the quantum level. The $\\left$ behavior, for the present model, is a drastic modification of the $\\left$ behavior in the corresponding commutative version of the present model. There, $\\left$ grows without limits with the time variable. Therefore, if the present model may represent the early stages of the Universe, the results of the present paper give an indication that $\\left$ may have been, initially, bounded due to noncommutativity.

G. Oliveira-Neto; M. Silva de Oliveira; G. A. Monerat; E. V. Corra Silva

2014-12-18T23:59:59.000Z

236

Bone-derived mesenchymal stromal cells from HIV transgenic mice exhibit altered proliferation, differentiation capacity and paracrine functions along with impaired therapeutic potential in kidney injury  

SciTech Connect (OSTI)

Mesenchymal stem cells (MSCs) secrete paracrine factors that could be cytoprotective and serve roles in immunoregulation during tissue injury. Although MSCs express HIV receptors, and co-receptors, and are susceptible to HIV infection, whether HIV-1 may affect biological properties of MSCs needs more study. We evaluated cellular proliferation, differentiation and paracrine functions of MSCs isolated from compact bones of healthy control mice and Tg26 HIV-1 transgenic mice. The ability of MSCs to protect against cisplatin toxicity was studied in cultured renal tubular cells as well as in intact mice. We successfully isolated MSCs from healthy mice and Tg26 HIV-1 transgenic mice and found the latter expressed viral Nef, Vpu, NL4-3 and Vif genes. The proliferation and differentiation of Tg26 HIV-1 MSCs was inferior to MSCs from healthy mice. Moreover, transplantation of Tg26 HIV-1 MSCs less effectively improved outcomes compared with healthy MSCs in mice with acute kidney injury. Also, Tg26 HIV-1 MSCs secreted multiple cytokines, but at significantly lower levels than healthy MSCs, which resulted in failure of conditioned medium from these MSCs to protect cultured renal tubular cells from cisplatin toxicity. Therefore, HIV-1 had adverse biological effects on MSCs extending to their proliferation, differentiation, function, and therapeutic potential. These findings will help in advancing mechanistical insight in renal injury and repair in the setting of HIV-1 infection. -- Highlights: MSCs isolated from HIV mice displayed HIV genes. MSCs isolated from HIV mice exhibited attenuated growth and paracrine functions. AKI mice with transplanted HIV-MSC displayed poor outcome. HIV-1 MSC secreted multiple cytokines but at a lower level.

Cheng, Kang; Rai, Partab; Lan, Xiqian; Plagov, Andrei; Malhotra, Ashwani [Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhassett, NY (United States); Gupta, Sanjeev [Departments of Medicine and Pathology, Marion Bessin Liver Research Center, Diabetes Center, Cancer Center, Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Institute for Clinical and Translational Research, Albert Einstein College of Medicine, Bronx, NY (United States); Singhal, Pravin C., E-mail: psinghal@nshs.edu [Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhassett, NY (United States)

2013-08-15T23:59:59.000Z

237

3, 221247, 2007 Modelling the Early  

E-Print Network [OSTI]

CPD 3, 221247, 2007 Modelling the Early Weichselian Eurasian Ice Sheets V. Peyaud et al. Title of the Past Modelling the Early Weichselian Eurasian Ice Sheets: role of ice shelves and influence of ice Weichselian Eurasian Ice Sheets V. Peyaud et al. Title Page Abstract Introduction Conclusions References

Boyer, Edmond

238

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing  

SciTech Connect (OSTI)

Antibody VRC01 is a human immunoglobulin that neutralizes about 90% of HIV-1 isolates. To understand how such broadly neutralizing antibodies develop, we used x-ray crystallography and 454 pyrosequencing to characterize additional VRC01-like antibodies from HIV-1-infected individuals. Crystal structures revealed a convergent mode of binding for diverse antibodies to the same CD4-binding-site epitope. A functional genomics analysis of expressed heavy and light chains revealed common pathways of antibody-heavy chain maturation, confined to the IGHV1-2*02 lineage, involving dozens of somatic changes, and capable of pairing with different light chains. Broadly neutralizing HIV-1 immunity associated with VRC01-like antibodies thus involves the evolution of antibodies to a highly affinity-matured state required to recognize an invariant viral structure, with lineages defined from thousands of sequences providing a genetic roadmap of their development.

Wu, Xueling; Zhou, Tongqing; Zhu, Jiang; Zhang, Baoshan; Georgiev, Ivelin; Wang, Charlene; Chen, Xuejun; Longo, Nancy S.; Louder, Mark; McKee, Krisha; O’ Dell, Sijy; Perfetto, Stephen; Schmidt, Stephen D.; Shi, Wei; Wu, Lan; Yang, Yongping; Yang, Zhi-Yong; Yang, Zhongjia; Zhang, Zhenhai; Bonsignori, Mattia; Crump, John A.; Kapiga, Saidi H.; Sam, Noel E.; Haynes, Barton F.; Simek, Melissa; Burton, Dennis R.; Koff, Wayne C.; Doria-Rose, Nicole A.; Connors, Mark; Mullikin, James C.; Nabel, Gary J.; Roederer, Mario; Shapiro, Lawrence; Kwong, Peter D.; Mascola, John R. (Tumaini); (NIH); (Duke); (Kilimanjaro Repro.); (IAVI)

2013-03-04T23:59:59.000Z

239

HIV/AIDS Information Resources from the National Library of Medicine-STOP  

SciTech Connect (OSTI)

The HIV/AIDS Information Resources from the National Library of Medicine training is designed specifically for the UNCFSP HBCU Screening, Testing, Outreach, and Prevention (STOP) HIV/AIDS Program project members to provide valuable health information resources from the National Library of Medicine and other reliable sources to increase awareness of the wealth of treatment information and educational materials that are available on the Internet and to improve prevention and treatment education for their clients. These resources will also meet the needs of community-based organizations

Templin-Branner, W. and N. Dancy

2010-06-15T23:59:59.000Z

240

aged korean adults: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AGING & SOCIETY Engineering Websites Summary: DEPARTMENT OF HEALTH, AGING & SOCIETY Monthly Speaker Series Dr. Ellen B. Ryan DATE TIME ROOM Department of Health, Aging, &...

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Materials Research in the Information Age  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Materials Research in the Information Age Accelerating Advanced Material Development NERSC Science Gateway a 'Google of Material Properties' October 31, 2011 | Tags: Materials...

242

Igneous processes of the early solar system  

E-Print Network [OSTI]

Experimental, petrographic and numerical methods are used to explore the igneous evolution of the early solar system. Chapters 1 and 2 detail the results of petrographic and experimental studies of a suite of primitive ...

Singletary, Steven J. (Steven James), 1973-

2004-01-01T23:59:59.000Z

243

Haptic holography : an early computational plastic  

E-Print Network [OSTI]

This dissertation introduces haptic holography, a combination of computational modeling and multimodal spatial display, as an early computationalplastic In this work, we combine various holographic displays with a force ...

Plesniak, Wendy J. (Wendy Jean)

2001-01-01T23:59:59.000Z

244

Early Detection Saves Lives | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Low-dose image scanner In 2000, the WHPP added low-dose CT scanning for early lung cancer detection to the medical screening on a pilot basis at a limited number of DOE sites,...

245

Paleoenvironmental implications of novel C[sub 30] steranes in Precambrian to Cenozoic age petroleum and bitumen  

SciTech Connect (OSTI)

Petroleums and bitumens from Early Proterozoic ([approx] 1800 Ma) to Miocene ([approx] 15 Ma) age marine strata contain 24-isopropylcholestanes, a novel group of C[sub 30] steroids. The abundance of these compounds, relative to 24-n-propylcholestanes, varies with source rock age. Late Proterozoic (Vendian) and Early Cambrian oils and/or bitumens from Siberia, the Urals, Oman, Australia, and India have a high ratio of 24-isopropylcholestanes to 24-n-propylcholestanes ([ge] 1), while younger and older samples have a low ratio ([le]0.4). Temporal changes in this parameter may reflect the relative abundance of certain Porifera (sponges) and certain Marine algae through time. Geochemical indicators such as this, which can constrain the source rock age of a migrated oil, are useful in source rock identification during petroleum exploration.

McCaffrey, M.A.; Lipton, P.A. (Chevron Petroleum Technology Company, La Habra, CA (United States)); Moldowan, J.M. (Cheveron Petroleum Technology Company, Richmond, CA (United States) Stanford Univ., CA (United States)); Summons, R.E. (Australian Geological Survey Organization, Canberra City (Australia)); Peters, K.E. (Chevron Overseas Petroleum Inc., San Ramon, CA (United States) Mobil Exploration and Producing Technical Center, Dallas, TX (United States)); Jeganathan, A.; Watt, D.S. (Univ. of Kentucky, Lexington, KY (United States))

1994-01-01T23:59:59.000Z

246

Grandmothers' Productivity and the HIV/AIDS Pandemic in Sub-Saharan Africa  

E-Print Network [OSTI]

, and in a population of a 1.3 million there are nearly 50,000 children who have lost one or both parents to HIV of extended families take on the parenting responsibilities for children orphaned by AIDS or whose parents are too sick to parent them (Ntozi 1997, Williams and Tumwekwase 2001, Monasch and Boerma 2004). Children

Bock, John

247

Extreme Genomics By Scouring the Genomes of 50 HIV-Resistant People, Study  

E-Print Network [OSTI]

Extreme Genomics By Scouring the Genomes of 50 HIV-Resistant People, Study Takes Aim at Rare Gene Genome Variation, and his colleagues think that the complete genome sequences of those fortunate few against the viral strain that usually infects humans. That's because the CCR5 protein is Extreme Genomics

Dolbow, John

248

VPR.A3A CHIMERA INHIBITS HIV REPLICATION Renato S. Aguiar1  

E-Print Network [OSTI]

1 VPR.A3A CHIMERA INHIBITS HIV REPLICATION Renato S. Aguiar1 , Nika Lovsin2 , Amilcar Tanuri3. Indeed, the Vpr.A3A chimera but not A3A was found abundantly in the viral core. It also restricted

Soloveichik, David

249

HIV-1-infected macrophages induce astrogliosis by SDF-1{alpha} and matrix metalloproteinases  

SciTech Connect (OSTI)

Brain macrophages/microglia and astrocytes are known to be involved in the pathogenesis of HIV-1-associated dementia (HAD). To clarify their interaction and contribution to the pathogenesis, HIV-1-infected or uninfected macrophages were used as a model of brain macrophages/microglia, and their effects on human astrocytes in vitro were examined. The culture supernatants of HIV-1-infected or uninfected macrophages induced significant astrocyte proliferation, which was annihilated with a neutralizing antibody to stromal cell-derived factor (SDF)-1{alpha} or a matrix metalloproteinase (MMP) inhibitor. In these astrocytes, CXCR4, MMP, and tissue inhibitors of matrix metalloproteinase mRNA expression and SDF-1{alpha} production were significantly up-regulated. The supernatants of infected macrophages were always more effective than those of uninfected cells. Moreover, the enhanced production of SDF-1{alpha} was suppressed by the MMP inhibitor. These results indicate that the activated and HIV-1-infected macrophages can indirectly induce astrocyte proliferation through up-regulating SDF-1{alpha} and MMP production, which implies a mechanism of astrogliosis in HAD.

Okamoto, Mika [Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544 (Japan); Wang, Xin [Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544 (Japan); Baba, Masanori [Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544 (Japan)]. E-mail: baba@m.kufm.kagoshima-u.ac.jp

2005-11-04T23:59:59.000Z

250

Structural properties of the histidine-containing loop in HIV-1RNase H  

SciTech Connect (OSTI)

The isolated HIV-1 RNase H domain is inactive. This inactivity has been linked to the lack of structure in the C-terminus of the isolated domain. His539 residing in a loop preceding the C-terminal Helix was studies by NMR to determine the stability and conformational properties of this region.

Kern, G.; Pelton, J.; Marqusee, S.; Kern, D.

2001-01-02T23:59:59.000Z

251

Effects of main-sequence mass loss on the turnoff ages of globular clusters  

SciTech Connect (OSTI)

Willson, Bowen, and Struck-Marcell have proposed that globular cluster main-sequence turnoff ages can be reconciled with the lower ages of the Galaxy and universe deduced from other methods by incorporating an epoch of early main-sequence mass-loss by stars of spectral types A through early-F. The proposed mass loss is pulsation-driven, and facilitated by rapid rotation. This paper presents stellar evolution calculations of Pop. II (Z = 0.001) mass-losing stars of initial mass 0.8 to 1.6 M/sub /circle dot//, with exponentially-decreasing mass loss rates of e-folding times 0.5 to 2.0 Gyr, evolving to a final mass of 0.7 M/sub /circle dot//. The calculations indicate that a globular cluster with apparent turnoff age 18 Gyr could have an actual age as low as /approximately/12 Gyr. Observational implications that may help to verify the hypothesis, e.g. low C/N abundance ratios among red giants following first dredge-up, blue stragglers, red giant deficiencies, and signatures in cluster mass/luminosity functions, are also discussed.25 refs., 4 figs., 3 tabs.

Guzik, J.A.

1989-01-01T23:59:59.000Z

252

Incorporating safety risk in early system architecture trade studies  

E-Print Network [OSTI]

Ideally, safety should be a part of the early decision making used in conceptual system design. However, effectively evaluating safety risk3 early enough to inform the early trade studies is not possible with current ...

Dulac, Nicholas

253

UNDEREMPLOYMENT AMONG MATURE AGE WORKERS IN AUSTRALIA  

E-Print Network [OSTI]

1 UNDEREMPLOYMENT AMONG MATURE AGE WORKERS IN AUSTRALIA * Jinjing Li1 , Alan Duncan2 and Riyana Miranti1 1 NATSEM, University of Canberra, Australia 2 Bankwest Curtin Economics Centre, Curtin University of underemployment for mature aged workers in Australia, and seeks in particular to determine the principal factors

254

6, 39453963, 2006 Methanol inside aged  

E-Print Network [OSTI]

. The oxidation of methane (and other hydrocarbons) can also produce methanol primarily via the self reactionACPD 6, 3945­3963, 2006 Methanol inside aged tropical biomass burning plumes G. Dufour et al. Title Chemistry and Physics Discussions First space-borne measurements of methanol inside aged tropical biomass

255

New age constraints on the Middle Stone Age occupations of Kharga Oasis, Western Desert, Egypt  

E-Print Network [OSTI]

New age constraints on the Middle Stone Age occupations of Kharga Oasis, Western Desert, Egypt rocks, or tufas, exposed along the flanks of the Libyan Plateau near Kharga Oasis, Western Desert, Egypt

Asmerom, Yemane

256

Deactivation of Accelerated Engine-Aged and Field-Aged SCR Catalysts...  

Broader source: Energy.gov (indexed) [DOE]

of Accelerated Engine-Aged and Field-Aged SCR Catalysts and the Role of the DOC Adam Foster and Ke Nguyen University of Tennessee - Knoxville Bruce G. Bunting and Todd J. Toops Oak...

257

Children's Development of Social Competences in Early Childhood Education.  

E-Print Network [OSTI]

??In this Master's thesis early environmental influences on childrens development of social competences were explored and an early childhood education programme aimed at fostering this (more)

Kristiansen, Mikkel Bjelke

2015-01-01T23:59:59.000Z

258

A Solution NMR Investigation into the Early Events of Amelogenin...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Solution NMR Investigation into the Early Events of Amelogenin Nanosphere Self-Assembly Initiated with Sodium Chloride or A Solution NMR Investigation into the Early Events of...

259

An agent-based approach to HIV/AIDS epidemic modeling : a case study of Papua New Guinea  

E-Print Network [OSTI]

Since AIDS was first discovered, mathematical models of the transmission dynamics of HIV have been developed to determine the drivers of the epidemic. It has become apparent that the most profound factor in the proliferation ...

Rhee, Alisa Joy

2006-01-01T23:59:59.000Z

260

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies  

E-Print Network [OSTI]

Broadly neutralizing HIV antibodies (bnAbs) are typically highly somatically mutated, raising doubts as to whether they can be elicited by vaccination. We used 454 sequencing and designed a novel phylogenetic method to ...

Sok, Devin

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Maybe his blood is still strong: a qualitative study among HIV-sero-discordant couples on ART in rural Uganda  

E-Print Network [OSTI]

of HIV-discordant couples in Uganda. AIDS Care 2005, 17:999couples receiving care in Uganda. BMC Public Health 2010,and their partners in rural Uganda. BMC Public Health 2011,

King, Rachel; Wamai, Nafuna; Khana, Kenneth; Johansson, Eva; Lindkvist, Pille; Bunnell, Rebecca

2012-01-01T23:59:59.000Z

262

Morbidity from HIV-associated neurocognitive disorders (HAND) continues to be a medical concern despite effective HAART.  

E-Print Network [OSTI]

+ lymphocyte cell count, APOE 4 genotype, fasting lipid profile, fasting plasma glucose, and 2-hour oral, current antiviral therapy, height, weight, waist circumference, blood pressure, plasma HIV viral load, CD4

Thompson, Paul

263

Case management to improve adherence for HIV-infected patients receiving antiretroviral therapy in Ethiopia: A micro-costing study  

E-Print Network [OSTI]

Factsheet. 2005. 4. PEPFAR Country Profiles: Ethiopia. [www.pepfar.gov/countries/ ethiopia/index.htm]. 5. ZwillichHospital. 2007, I-TECH Ethiopia. 14. Monthly HIV Care and

2011-01-01T23:59:59.000Z

264

Maturation of the viral core enhances the fusion of HIV-1 particles with primary human T cells and monocyte-derived macrophages  

SciTech Connect (OSTI)

HIV-1 infection requires fusion of viral and cellular membranes in a reaction catalyzed by the viral envelope proteins gp120 and gp41. We recently reported that efficient HIV-1 particle fusion with target cells is linked to maturation of the viral core by an activity of the gp41 cytoplasmic domain. Here, we show that maturation enhances the fusion of a variety of recombinant viruses bearing primary and laboratory-adapted Env proteins with primary human CD4{sup +} T cells. Overall, HIV-1 fusion was more dependent on maturation for viruses bearing X4-tropic envelope proteins than for R5-tropic viruses. Fusion of HIV-1 with monocyte-derived macrophages was also dependent on particle maturation. We conclude that the ability to couple fusion to particle maturation is a common feature of HIV-1 Env proteins and may play an important role during HIV-1 replication in vivo.

Jiang Jiyang [Department of Microbiology and Immunology, Vanderbilt University School of Medicine, A-5301 Medical Center North, Nashville, TN 37232-2363 (United States); Aiken, Christopher [Department of Microbiology and Immunology, Vanderbilt University School of Medicine, A-5301 Medical Center North, Nashville, TN 37232-2363 (United States)]. E-mail: chris.aiken@vanderbilt.edu

2006-03-15T23:59:59.000Z

265

Computational Age Dating of Special Nuclear Materials  

SciTech Connect (OSTI)

This slide-show presented an overview of the Constrained Progressive Reversal (CPR) method for computing decays, age dating, and spoof detecting. The CPR method is: Capable of temporal profiling a SNM sample; Precise (compared with known decay code, such a ORIGEN); Easy (for computer implementation and analysis). ? We have illustrated with real SNM data using CPR for age dating and spoof detection. If SNM is pure, may use CPR to derive its age. If SNM is mixed, CPR will indicate that it is mixed or spoofed.

None

2012-06-30T23:59:59.000Z

266

Early Fasting Is Long Lasting: Differences in Early Nutritional Conditions Reappear under Stressful  

E-Print Network [OSTI]

lead to differences in growth, reproductive success and survival. Yet, under natural conditions shorterEarly Fasting Is Long Lasting: Differences in Early Nutritional Conditions Reappear under Stressful Conditions in Adult Female Zebra Finches E. Tobias Krause1 *, Mariam Honarmand1 , Jennifer Wetzel1 , Marc

Richner, Heinz

267

Early Adopter PDC AtEarly Adopter PDC At Washington and LeeWashington and Lee  

E-Print Network [OSTI]

Early Adopter ­ PDC AtEarly Adopter ­ PDC At Washington and LeeWashington and Lee Four-year Liberal with and manipulation of collections of stuff.manipulation of collections of stuff. · PDC applications: sorting, recursive treePDC applications: sorting, recursive tree structures, image processing,...structures, image

Stough, Joshua

268

Energy density fluctuations in early universe  

SciTech Connect (OSTI)

The primordial nucleosinthesys of the element can be influenced by the transitions of phase that take place after the Big Bang, such as the QCD transition. In order to study the effect of this phase transition, in this work we compute the time evolution of thermodynamical quantities of the early universe, focusing on temperature and energy density fluctuations, by solving the relevant equations of motion using as input the lattice QCD equation of state to describe the strongly interacting matter in the early universe plasma. We also study the effect of a primordial strong magnetic field by means of a phenomenological equation of state. Our results show that small inhomogeneities of strongly interacting matter in the early Universe are moderately damped during the crossover.

Guardo, G. L.; Ruggieri, M. [Department of Physics and Astronomy, University of Catania, Catania (Italy); Greco, V. [Department of Physics and Astronomy, University of Catania, Catania, Italy and INFN - Laboratori Nazionali del Sud, Catania (Italy)

2014-05-09T23:59:59.000Z

269

Virgo Early-Type Dwarfs in ALFALFA  

E-Print Network [OSTI]

Early-type dwarf galaxies dominate cluster populations, but their formation and evolutionary histories are poorly understood. The ALFALFA (Arecibo Legacy Fast ALFA) survey has completed observations of the Virgo Cluster in the declination range of 6 - 16 degrees. Less than 2% of the early-type dwarf population is detected, a significantly lower fraction than reported in previous papers based on more limited samples. In contrast ~30 of the irregular/BCD dwarf population is detected. The detected early-type galaxies tend to be located in the outer regions of the cluster, with a concentration in the direction of the M Cloud. Many show evidence for ongoing/recent star formation. Galaxies such as these may be undergoing morphological transition due to cluster environmental effects.

Koopmann, Rebecca A

2007-01-01T23:59:59.000Z

270

Virgo Early-Type Dwarfs in ALFALFA  

E-Print Network [OSTI]

Early-type dwarf galaxies dominate cluster populations, but their formation and evolutionary histories are poorly understood. The ALFALFA (Arecibo Legacy Fast ALFA) survey has completed observations of the Virgo Cluster in the declination range of 6 - 16 degrees. Less than 2% of the early-type dwarf population is detected, a significantly lower fraction than reported in previous papers based on more limited samples. In contrast ~30 of the irregular/BCD dwarf population is detected. The detected early-type galaxies tend to be located in the outer regions of the cluster, with a concentration in the direction of the M Cloud. Many show evidence for ongoing/recent star formation. Galaxies such as these may be undergoing morphological transition due to cluster environmental effects.

Rebecca A. Koopmann

2007-07-22T23:59:59.000Z

271

Viral persistence, latent reservoir, and blips: a review on HIV-1 dynamics and modeling during HAART and related treatment implications  

SciTech Connect (OSTI)

HIV-1 eradication from infected individuals has not been achieved with the use of highly active antiretroviral therapy (HAART) for a prolonged period of time. The cellular reservoir for HIV-1 in resting memory CD4{sup +} T cells remains a major obstacle to viral elimination. The reservoir does not decay significantly over long periods of time as is able to release replication competent HIV-1 upon cell activation. Residual ongoing viral replication may likely occur in many patients because low levels of virus can be detected in plasma by sensitive assays and transient episodes of viremia, or HIV-1 blips, are often observed in patients even with successful viral suppression for many years. Here we review our current knowledge of the factors contributing to viral persistence, the latent reservoir, and blips, and mathematical models developed to explore them and their relationships. We show how mathematical modeling can help improve our understanding of HIV-1 dynamics in patients on HAART and the quantitative events underlying HIV-1 latency, reservoir stability, low-level viremic persistence, and emergence of intermittent viral blips. We also discuss treatment implications related to these studies.

Rong, Libin [Los Alamos National Laboratory; Perelson, Alan [Los Alamos National Laboratory

2008-01-01T23:59:59.000Z

272

Supersymmetry in the Very Early Universe  

E-Print Network [OSTI]

Supersymmetric flat directions can have a number of important consequences in the very early universe. Depending on the form of the SUSY breaking potential arising from the finite energy density at early times, coherent production of scalar condensates can result along such directions. This leads a cosmological disaster for Polonyi type flat directions with only Planck suppressed couplings, but can give rise to the baryon asymmetry for standard model flat directions. Flat directions are also natural candidates to act as inflatons. Achieving density fluctuations of the correct magnitude generally requires an additional hidden SUSY breaking sector.

Scott Thomas

1995-06-24T23:59:59.000Z

273

Early Science Program | Argonne Leadership Computing Facility  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series toESnet4: Networking for the Future of DOE ScienceEarly EdisonLessonsEarly

274

Early planning for construction of Y-12  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed NewcatalystNeutronEnvironmentZIRKLE FRUIT reducesEarly Career: Emergent... Early

275

THE INITIAL MASS FUNCTION OF EARLY-TYPE GALAXIES  

SciTech Connect (OSTI)

We determine an absolute calibration of the initial mass function (IMF) of early-type galaxies, by studying a sample of 56 gravitational lenses identified by the Sloan Lenses ACS Survey. Under the assumption of standard Navarro, Frenk, and White dark matter halos, a combination of lensing, dynamical, and stellar population synthesis models is used to disentangle the stellar and dark matter contribution for each lens. We define an 'IMF mismatch' parameter alphaident toM {sup LD}{sub *,Ein}/M {sup SPS}{sub *,Ein} as the ratio of stellar mass inferred by a joint lensing and dynamical model (M {sup LD}{sub *,Ein}) to the current stellar mass inferred from stellar populations synthesis models (M {sup SPS}{sub *,Ein}). We find that a Salpeter IMF provides stellar masses in agreement with those inferred by lensing and dynamical models ((log alpha) = -0.00 +- 0.03 +- 0.02), while a Chabrier IMF underestimates them ((log alpha) = 0.25 +- 0.03 +- 0.02). A tentative trend is found, in the sense that alpha appears to increase with galaxy velocity dispersion. Taken at face value, this result would imply a non-universal IMF, perhaps dependent on metallicity, age, or abundance ratios of the stellar populations. Alternatively, the observed trend may imply non-universal dark matter halos with inner density slope increasing with velocity dispersion. While the degeneracy between the two interpretations cannot be broken without additional information, the data imply that massive early-type galaxies cannot have both a universal IMF and universal dark matter halos.

Treu, Tommaso; Auger, Matthew W.; Gavazzi, Raphael; Marshall, Philip J. [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Koopmans, Leon V. E. [Kapteyn Institute, P.O. Box 800, 9700AV Groningen (Netherlands); Bolton, Adam S., E-mail: tt@physics.ucsb.ed, E-mail: mauger@physics.ucsb.ed, E-mail: pjm@physics.ucsb.ed, E-mail: koopmans@astro.rug.n, E-mail: gavazzi@iap.f, E-mail: bolton@ifa.hawaii.ed, E-mail: bolton@physics.utah.ed [Institute for Astronomy, University of Hawai'i, 2680 Woodlawn Dr., Honolulu, HI 96822 (United States)

2010-02-01T23:59:59.000Z

276

HYGROTHERMAL AGING OF POLYIMIDE MATRIX COMPOSITE LAMINATES  

E-Print Network [OSTI]

. The time to initiate water-induced microcracks, tm, (in minutes), was log .t T m = + 3423 1 35 (1) #12-ply laminates and supplied to us by the Boeing Company. For hygrothermal aging experiments, a series

Nairn, John A.

277

Aging of polymeric composites : a literature review  

E-Print Network [OSTI]

Due to their increased use in today's society, an extensive survey was undertaken in this report to condense what's been, thus far, discovered as to the effects of aging on polymeric composites. Special emphasis was placed ...

Trevio-Garrido, Margie N

2013-01-01T23:59:59.000Z

278

QUANTITY SEX AGE WEIGHT WITH: VENDOR  

E-Print Network [OSTI]

QUANTITY SEX AGE WEIGHT NUMBER/ CAGE WITH: VENDOR: REFERENCE No: PO No: FACILITY: RECEIVED ON PLACED BY: DATE: SUGGESTED VENDOR: AUP No: USER's PHONE No: USER's NAME: USER's EMAIL: ANIMAL REQUEST

Arnold, Jonathan

279

June 18, 2012 Symposium on Aging  

E-Print Network [OSTI]

, anemia, muscular dystrophy, and diabetes. The reasons for accelerating research into the molecular diseases of aging such as diabetes, cancer, Alzheimer's and heart disease. Today's attendees come not only

Church, George M.

280

Applications of a single-molecule detection in early disease diagnosis and enzymatic reaction study  

SciTech Connect (OSTI)

Various single-molecule techniques were utilized for ultra-sensitive early diagnosis of viral DNA and antigen and basic mechanism study of enzymatic reactions. DNA of human papilloma virus (HPV) served as the screening target in a flow system. Alexa Fluor 532 (AF532) labeled single-stranded DNA probes were hybridized to the target HPV-16 DNA in solution. The individual hybridized molecules were imaged with an intensified charge-coupled device (ICCD) in two ways. In the single-color mode, target molecules were detected via fluorescence from hybridized probes only. This system could detect HPV-16 DNA in the presence of human genomic DNA down to 0.7 copy/cell and had a linear dynamic range of over 6 orders of magnitude. In the dual-color mode, fluorescence resonance energy transfer (FRET) was employed to achieve zero false-positive count. We also showed that DNA extracts from Pap test specimens did not interfere with the system. A surface-based method was used to improve the throughput of the flow system. HPV-16 DNA was hybridized to probes on a glass surface and detected with a total internal reflection fluorescence (TIRF) microscope. In the single-probe mode, the whole genome and target DNA were fluorescently labeled before hybridization, and the detection limit is similar to the flow system. In the dual-probe mode, a second probe was introduced. The linear dynamic range covers 1.44-7000 copies/cell, which is typical of early infection to near-cancer stages. The dual-probe method was tested with a crudely prepared sample. Even with reduced hybridization efficiency caused by the interference of cellular materials, we were still able to differentiate infected cells from healthy cells. Detection and quantification of viral antigen with a novel single-molecule immunosorbent assay (SMISA) was achieved. Antigen from human immunodeficiency virus type 1(HIV-1) was chosen to be the target in this study. The target was sandwiched between a monoclonal capture antibody and a polyclonal detector antibody. The capture antibody was covalently immobilized on modified glass slides. The detector antibody was conjugated with AF532 labeled secondary antibody prior to being used as probe for the antigen. Imaging was performed with a TIRF system. This technique is demonstrated for detecting HIV-1 p24 antigen down to 0.1 pg/mL with a dynamic range of over 4 orders of magnitude. A Langmuir isotherm fit the molecule count dependence on the target concentration. The results also showed that neither sensitivity nor dynamic range was affected by the biological matrix. SMISA is therefore a promising approach for the early diagnosis of virus-induced diseases. Single-molecule enzymatic kinetics and enantioselectivity were monitored in real time by using TIRF microscopy. AF532 labeled poly-L-lysine (PLL) or poly-D-lysine (PDL) was covalently immobilized on a dithiobis (succinimidyl undecanoate) self-assembled monolayer (DSU SAM). Chain shortening due to enzymatic hydrolysis resulted in the reduction of the individual fluorescence intensities. A broad distribution was obtained when 100 single-molecule half-lives were analyzed. However, the detailed hydrolysis process involved also a long-lived component and an induction period that varied significantly among molecules. Charge and steric heterogeneity at the surface are responsible for these features.

Li, Jiangwei

2008-10-15T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Journal of Climate EARLY ONLINE RELEASE  

E-Print Network [OSTI]

investigate the climate dynamic feedbacks during a transition from the present climate7 to the extremely coldJournal of Climate EARLY ONLINE RELEASE This is a preliminary PDF of the author-produced manuscript. Hu, 2011: The initiation of modern "soft Snowball" and "hard Snowball" climates in CCSM3. Part II

Hu, Yongyun

282

Heart Disease and Early Heart Attack Care  

E-Print Network [OSTI]

Heart Disease and Early Heart Attack Care Pamela Kostic, RN, CCCC, Chest Pain Coordinator, Stony Risk Factors · EHAC & Prevention #12;Heart disease includes a number of problems affecting the heart and the blood vessels in the heart. #12;Types of heart disease include: · Coronary artery disease (CAD) · Angina

Ohta, Shigemi

283

Early diagenetic transformations of peat Original research  

E-Print Network [OSTI]

Early diagenetic transformations of peat Original research Organic matter sources and decay;KEY WORDS: bioindicators - carbohydrates - labile organic matter - peat botanical composition to the fate of organic matter (OM) in the underlying peat. Our aims were to determine how moisture conditions

Paris-Sud XI, Universit de

284

Preserving the Colors of Early Cinema  

E-Print Network [OSTI]

Preserving the Colors of Early Cinema through the Davide Turconi Film Frame Collection Joshua of Chicago 4pm Wed, Sept. 27 Auditorium of the Center for Imaging Science While most surviving silent films as well as Kinetoscope films were colored. Color has thus existed in the cinema since its inception, yet

Zanibbi, Richard

285

Evolution of self-incompatibility: Early Views  

E-Print Network [OSTI]

Evolution of self-incompatibility: Early Views: Whitehouse (1950): 1. Sudden rise of angiosperms by Whitehouse (1950). Isolation of components of the self-incompatibilities paved the way to study the evolution of SIs Matton et al. (1994): Molecular data supports Bateman. Three self-incompatibility systems

Bhattacharyya, Madan Kumar

286

Protein conformational dynamics in the mechanism of HIV-1 protease catalysis  

SciTech Connect (OSTI)

We have used chemical protein synthesis and advanced physical methods to probe dynamics-function correlations for the HIV-1 protease, an enzyme that has received considerable attention as a target for the treatment of AIDS. Chemical synthesis was used to prepare a series of unique analogues of the HIV-1 protease in which the flexibility of the 'flap' structures (residues 37-61 in each monomer of the homodimeric protein molecule) was systematically varied. These analogue enzymes were further studied by X-ray crystallography, NMR relaxation, and pulse-EPR methods, in conjunction with molecular dynamics simulations. We show that conformational isomerization in the flaps is correlated with structural reorganization of residues in the active site, and that it is preorganization of the active site that is a rate-limiting factor in catalysis.

Torbeev, Vladimir Yu.; Raghuraman, H.; Hamelberg, Donald; Tonelli, Marco; Westler, William M.; Perozo, Eduardo; Kent, Stephen B.H. (GSU); (UW); (UC)

2013-09-17T23:59:59.000Z

287

Misalignment between cold gas and stellar components in early-type galaxies  

E-Print Network [OSTI]

Recent work suggests blue ellipticals form in mergers and migrate quickly from the blue cloud of star-forming galaxies to the red sequence of passively evolving galaxies, perhaps as a result of black hole feedback. Such rapid reddening of stellar populations implies that large gas reservoirs in the pre-merger star-forming pair must be depleted on short time scales. Here we present pilot observations of atomic hydrogen gas in four blue early-type galaxies that reveal increasing spatial offsets between the gas reservoirs and the stellar components of the galaxies, with advancing post-starburst age. Emission line spectra show associated nuclear activity in two of the merged galaxies, and in one case radio lobes aligned with the displaced gas reservoir. These early results suggest that a kinetic process (possibly feedback from black hole activity) is driving the quick truncation of star formation in these systems, rather than a simple exhaustion of gas supply.

Wong, O Ivy; Jzsa, G I G; Urry, C M; Lintott, C J; Simmons, B D; Kaviraj, S; Masters, K L

2015-01-01T23:59:59.000Z

288

Structural and Functional Studies of the Receptor-binding and Glycosaminogly-canbinding Mechanisms of a Viral Chemokine Analog vMIP-II and Rational Design of Chemokine-based Highly Potent HIV-1 Entry Inhibitors  

E-Print Network [OSTI]

............................................................................................... 82 Table 4.1 Anti-HIV activities of the chimeric inhibitors in R5 cell-cell fusion assay ................................................................................................... 102 Table 4.2 Anti-HIV activities of the chimeric... assay ......... 106 Table 4.6 Anti-HIV activities of the chimeric inhibitors in X4 cell-cell fusion assay ................................................................................................... 106 Table 4.7 Anti-HIV activities of 5P...

Zhao, Bo

2012-07-16T23:59:59.000Z

289

An HIV Feedback-Resistor: Auto-Regulatory Circuit Deactivator and Noise Buffer  

E-Print Network [OSTI]

Many viruses have the cunning ability to enter a hibernative or off state, termed latency or lysogeny. When in a latent state, the virus is unable to replicate, and its gene expression program is largely shut down. This facility for lying dormant typically ensures lifelong persistence of the virus in the host; it is also a particularly problematic obstacle in the treatment of HIV. For most viruses, the molecular regulation of entry into latency is not completely understood, but it is believed that viral gene expression must be deactivated in some way. In this study, we introduce a new regulatory motif, the feedback resistor, that enables a genetic circuit to shut off without the need for an active repressor molecule. We first show that many animal viruses might encode feedback resistors in their regulatory circuits. Then, by using a combination of mathematical theory and single-cell real-time imaging experiments, we show that a feedback resistor in the HIV Tat transcriptional circuit likely allows the HIV virus to enter into latency. We postulate that feedback resistors may give increased stability and control in the complex noisy signaling environment of the cell.

Leor S. Weinberger; Thomas Shenk

2007-01-09T23:59:59.000Z

290

E-Print Network 3.0 - aging society aging Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of two different aging techniques. ... Source: South Dakota State University, Climate Change and Prairie Wetlands Program Collection: Environmental Sciences and Ecology ;...

291

E-Print Network 3.0 - age gestational age Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Collection: Energy Storage, Conversion and Utilization 25 Pregnancy ComplicationsHealth Problems Complication Explanation Summary: her gestational age. (Sometimes referred to as...

292

Two-step build-up of a thermoreversible polymer network: From early local to late collective dynamics  

E-Print Network [OSTI]

We probe the mechanisms at work in the build-up of thermoreversible gel networks, with the help of hybrid gelatin gels containing a controlled density of irreversible, covalent crosslinks (CL), which we quench below the physical gelation temperature. The detailed analysis of the dependence on covalent crosslink density of both the shear modulus and optical activity evolutions with time after quench enables us to identify two stages of the physical gelation process, separated by a temperature dependent crossover modulus: (i) an early nucleation regime during which rearrangements of the triple-helix CL play a negligible role, (ii) a late, logarithmic aging one, which is preserved, though slowed down, in the presence of irreversible CL. We show that aging is fully controlled by rearrangements and discuss the implication of our results in terms of the switch from an early, local dynamics to a late, cooperative long-range one.

H. Souguir; O. Ronsin; C. Caroli; T. Baumberger

2015-03-05T23:59:59.000Z

293

Restructuring and aging in a capillary suspension  

E-Print Network [OSTI]

The rheological properties of capillary suspensions, suspensions with small amounts of an added immiscible fluid, are dramatically altered with the addition of the secondary fluid. We investigate a capillary suspension to determine how the network ages and restructures at rest and under applied external shear deformation. The present work uses calcium carbonate suspended in silicone oil (11 % solids) with added water as a model system. Aging of capillary suspensions and their response to applied oscillatory shear is distinctly different from particulate gels dominated by the van der Waals forces. The suspensions dominated by the capillary force are very sensitive to oscillatory flow, with the linear viscoelastic regime ending at a deformation of only 0.1 % and demonstrating power-law aging behavior. This aging persists for long times at low deformations or for shorter times with a sudden decrease in the strength at higher deformations. This aging behavior suggests that the network is able to rearrange and even rupture. This same sensitivity is not demonstrated in shear flow where very high shear rates are required to rupture the agglomerates returning the apparent viscosity of capillary suspensions to the same viscosity as for the pure vdW suspension. A transitional region is also present at intermediate water contents wherein the material response depends very strongly on the type, strength, and duration of the external forcing.

Erin Koos; Wolfgang Kannowade; Norbert Willenbacher

2014-10-16T23:59:59.000Z

294

Globular Cluster Ages and Stromgren CCD Photometry  

E-Print Network [OSTI]

Stromgren uvby CCD photometry can be used in a variety of ways to constrain the absolute and relative ages of globular clusters. The reddening corrected (v-y, c1) diagram offers the means to derive ages that are completely independent of distance. Very precise differential ages for clusters of the same chemical composition may also be determined from such 2-color plots, or from measurements of the magnitude difference, Delta_u, between the subgiant and horizontal branches on the $u-y, u$ plane (where both of these features are flat and well-defined, even for clusters like M13 that have extremely blue HBs on the (B-V, V) diagram). Based on high-quality photometry we find that: (1) M92 is 15 Gyr old, (2) M3 and M13 differ in age by < 1 Gyr, and (3) NGC 288, NGC 362, and NGC 1851 are coeval to within ~1.5 Gyr. These results strongly suggest that age cannot be the only ``second parameter''. Finally, we suggest that the observed variations in c1 among giant branch stars in all the metal-poor clusters that we have studied so far are likely due to star-to-star C and N abundance variations, and potentially indicate that most (if not all) globular clusters have ``primordial'' variations in at least these elements.

Frank Grundahl

1999-09-23T23:59:59.000Z

295

Early-age concrete temperature and moisture relative to curing effectiveness and projected effects on selected aspects of slab behavior  

E-Print Network [OSTI]

-desiccation. A full scale concrete pavement test study was conducted at the FAA National Airport Pavement Test Facility (NAPTF) near Atlantic City, New Jersey. In this study, the material properties, i.e. thermal conductivity and moisture diffusivity, were...

Ye, Dan

2009-05-15T23:59:59.000Z

296

Does the early frog catch the worm? Disentangling potential drivers of a parasite age-intensity relationship in tadpoles  

E-Print Network [OSTI]

species in individual tad- poles, regardless of which wasencystment rates in late-stage tad- poles were also observeddevelopmental stagesbetween tad- poles identified as first-

Raffel, TR; Lloyd-Smith, JO; Sessions, SK; Hudson, PJ; Rohr, JR

2011-01-01T23:59:59.000Z

297

Feeding the periphery : modeling early Bronze Age economies and the cultural landscape of the Faynan District, Southern Jordan  

E-Print Network [OSTI]

and desertification in Wadi Faynan. Levant 32, 32:27-52.and Land Use in the Wadi Faynan, Southern Jordan: The Thirdand Desertification in the Wadi Faynan: The Fourth (1999)

Muniz, Adolfo A.

2007-01-01T23:59:59.000Z

298

Innovative practices in early childhood classrooms: what makes a teacher an early adopter?  

E-Print Network [OSTI]

This basic qualitative research study focused on the internal constructions of ten early childhood education teachers who take new information acquired from workshops, coursework, or other educational venues and quickly incorporate...

Marshall, Ellen

2004-09-30T23:59:59.000Z

299

Bulk Flows and End of the Dark Ages with the SKA  

E-Print Network [OSTI]

The early Universe is a precious probe of the birth of primordial objects, first star formation events and consequent production of photons and heavy elements. Higher-order corrections to the cosmological linear perturbation theory predicts the formation of coherent supersonic gaseous streaming motions at decoupling time. These bulk flows impact the gas cooling process and determine a cascade effect on the whole baryon evolution. By analytical estimates and N-body hydrodynamical chemistry numerical simulations including atomic and molecular evolution, gas cooling, star formation, feedback effects and metal spreading for individual species from different stellar populations according to the proper yields and lifetimes, we discuss the role of these primordial bulk flows at the end of the dark ages and their detectable impacts during the first Gyr in view of the upcoming SKA mission. Early bulk flows can inhibit molecular gas cooling capabilities, suppressing star formation, metal spreading and the abundance of ...

Maio, Umberto; Koopmans, Leon V E

2015-01-01T23:59:59.000Z

300

A review of "Conscience on Stage: The Comedia as Casuistry in Early Modern Spain" by Hillaire Kallendorf  

E-Print Network [OSTI]

, social and cultural historians? (20). Hilaire Kallendorf. Conscience on Stage: The Comedia as Casuistry in Early Modern Spain. Toronto: University of Toronto Press, 2007. x + 299 pp. $65. Review by elizabeth r. wright, university of georgia. Spain?s... playwrights. Yet a miniscule proportion of plays have attracted careful and sustained scholarly scrutiny or are performed regularly in repertories. This book reports on one scholar?s project to widen the lens through which we view Spain?s ?Golden Age...

Wright, Elizabeth

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

A review of "Dictionaries in Early Modern Europe: Lexicography and the Making of Heritage" by John Considine  

E-Print Network [OSTI]

reviews 1 John Considine. Dictionaries in Early Modern Europe: Lexicography and the Making of Heritage. Cambridge: Cambridge University Press, 2008. xiv + 393 pp. $99.00. Review by eugene d. hill, mount holyoke college. John Considine?s fine... account is given of him. His important and influential work Donne at Sermons: A Christian Existen- tial World (1972), however, is a presence that hovers over the whole volume. But his last work, a collaboration with James D. Hardy, Jr., Age of Iron...

Hill, Eugene D.

2010-01-01T23:59:59.000Z

302

Journal of the Geological Society, London, Vol. 163, 2006, pp. 291301. Printed in Great Britain. Early Silurian maficultramafic and granitic plutonism in contemporaneous flysch,  

E-Print Network [OSTI]

. 291 Early Silurian mafic­ultramafic and granitic plutonism in contemporaneous flysch, Magerøy and regional metamorphism and were intruded by a mafic­ultramafic complex and various granitic plutons. U granite and 437.7 ? 1.6 Ma for the Finnvik granite coincide within error with the age of deposition

Andersen, Torgeir Bjørge

303

Early modern human settlement of Europe north of the Alps occurred 43,500 years ago in a cold steppe-type environment  

E-Print Network [OSTI]

. White M, Pettitt P (2012) Ancient Digs and Modern Myths: The Age and Context of the Kent's Cavern 4 Maxilla and the Earliest Homo sapiens Specimens in Europe. European Journal of Archaeology 15:392420. 12. Hublin JJ (2013) The Makers of the Early Upper...

Nigst, Philip R.; Haesaerts, Paul; Damblon, Freddy; Frank-Fellner, Christa; Mallol, Carolina; Gtzinger, Michael; Niven, Laura; Trnka, Gerhard; Hublin, Jean-Jacques

2014-09-22T23:59:59.000Z

304

Predicting the future: A fish story. Prokaryotic genetics has an illustrious past. In its early days, it helped us learn how  

E-Print Network [OSTI]

Predicting the future: A fish story. Prokaryotic genetics has an illustrious past. In its early. But first the fish story...... A fish story - Once upon a time, some very bright and ambitious fishermen set out to catch the very biggest fish of their age ­ the hereditary material, mutation, replication

California at Davis, University of

305

A survey of early warning technologies  

SciTech Connect (OSTI)

This paper presents a survey of technologies useful in providing early warning in physical security systems. Early warning is important in virtually all types of security systems whether they are used for temporary (tactical, portable, or semi-permanent) applications, border warning, fixed-site detection, or standoff surveillance detection. With the exception of the standoff surveillance detection systems, all systems discussed in this paper usually involve a moving target. The fact that a person(s) to be detected in a standoff surveillance scenario is not moving presents challenging problems and requires different applications of technology. The technologies commonly used to detect moving targets and some suggestions for detection of stationary targets are addressed in this paper.

Smith, G.D.; Arlowe, H.D.; Williams, J.D.

1995-07-01T23:59:59.000Z

306

Photochemical Escape of Oxygen from Early Mars  

E-Print Network [OSTI]

Photochemical escape is an important process for oxygen escape from present Mars. In this work, a 1-D Monte-Carlo Model is developed to calculate escape rates of energetic oxygen atoms produced from O2+ dissociative recombination reactions (DR) under 1, 3, 10, and 20 times present solar XUV fluxes. We found that although the overall DR rates increase with solar XUV flux almost linearly, oxygen escape rate increases from 1 to 10 times present solar XUV conditions but decreases when increasing solar XUV flux further. Analysis shows that atomic species in the upper thermosphere of early Mars increases more rapidly than O2+ when increasing XUV fluxes. While the latter is the source of energetic O atoms, the former increases the collision probability and thus decreases the escape probability of energetic O. Our results suggest that photochemical escape be a less important escape mechanism than previously thought for the loss of water and/or CO2 from early Mars.

Zhao, Jinjin

2015-01-01T23:59:59.000Z

307

Early Standard Model measurements with ATLAS  

E-Print Network [OSTI]

The measurement of Standard Model processes will be an important first step towards exploiting the discovery potential of the Large Hadron Collider, the highest energy accelerator ever built that will begin operation in the fall 2009. This paper presents a summary of the early physics analyses for understanding the performance of the detector as well as the Standard Model at the ATLAS experiment at 14 TeV centre of mass energy.

T. Ince; for the ATLAS collaboration

2009-05-28T23:59:59.000Z

308

Early B-physics at ATLAS  

E-Print Network [OSTI]

The B-physics program at the ATLAS experiment, which covers the mid-rapidity region, complements that at the dedicated LHCb experiment, which covers the forward rapidity region. At the early stage of the LHC operation, the program concentrated on understanding of detector performance and measurements of quarkonia and D mesons. This article presents recent results of the B-physics program at ATLAS.

S. Oda; on behalf of the ATLAS Collaboration

2010-10-18T23:59:59.000Z

309

Early Events in Ionic Liquid Radiation Chemistry  

SciTech Connect (OSTI)

Ionic liquids are interesting and useful materials whose solvation time scales are up to thousands of times longer than in conventional solvents. The extended lifetimes of pre-solvated electrons and other energetic species in ionic liquids has profound consequences for the radiolytic product distributions and reactivity patterns. We use a newly developed, multiplexed variation of pulse-probe spectroscopy to measure the kinetics of the early dynamical and reactive events in ionic liquids.

Wishart, J.F.; Cook, A.; Rimmer, R.D.; Gohdo, M.

2010-09-14T23:59:59.000Z

310

Died suddenly under age 50 Heart disease  

E-Print Network [OSTI]

­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­ _____________________________________________________________ Student cell phone Current email address (for contact over the summer) Persons to contact in case _________________________________________________ _________________________________________________ Home phone Business phone Cell phone Home phone Business phone Cell phone State of Age at Age Health _________________________________________________ _________________________________________________ City State Zip Code Nation (if not US) Home phone

Smith, Marc L.

311

aging tumor growth: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

1983), provide valuable data on the age 85 AGE AND GROWTH OF SKIPJACK TUNA, KATSUWONUS PELAMIS, AND YELLOWFIN TUNA, THUNNUS ALBACARES, AS INDICATED Environmental Sciences and...

312

Diagnostic and Prognostic Analysis of Battery Performance & Aging...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

and Prognostic Analysis of Battery Performance & Aging based on Kinetic and Thermodynamic Principles Diagnostic and Prognostic Analysis of Battery Performance & Aging based on...

313

Rapid Aging Protocols for Diesel Aftertreatment Devices: NOx...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Rapid Aging Protocols for Diesel Aftertreatment Devices: NOx Abatement Catalysts Rapid Aging Protocols for Diesel Aftertreatment Devices: NOx Abatement Catalysts Poster...

314

Accelerated Aging of Roofing Surfaces | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Accelerated Aging of Roofing Surfaces Accelerated Aging of Roofing Surfaces Emerging Technologies Project for the 2013 Building Technologies Office's Program Peer Review...

315

THYROID HORMONE REVERSES AGING-INDUCED MYOCARDIAL FATTY ACID...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

occurs during aging in humans and mice and may contribute to development of heart failure. Aging also impairs myocardial fatty acid oxidation, causing increased...

316

Review: Glut: Mastering Information throughout the Ages by Alex Wright  

E-Print Network [OSTI]

In positing his proposal, Wright has provided the literaturethrough the Ages by Alex Wright. Washington: Joseph Henrythrough the Ages, Alex Wright may have uncovered one such

Haley, Dan

2008-01-01T23:59:59.000Z

317

Solid-State Nuclear Magnetic Resonance Evidence for Parallel and Antiparallel Strand Arrangements in the Membrane-Associated HIV-1 Fusion Peptide  

E-Print Network [OSTI]

Solid-State Nuclear Magnetic Resonance Evidence for Parallel and Antiparallel Strand Arrangements in the Membrane-Associated HIV-1 Fusion Peptide Jun Yang and David P. Weliky* Department of Chemistry, Michigan 7, 2003 ABSTRACT: The HIV-1 fusion peptide serves as a useful model system for understanding viral

Weliky, David

318

Effects of CCR5-32, CCR2-64I, and SDF-1 3 A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of  

E-Print Network [OSTI]

Effects of CCR5- 32, CCR2-64I, and SDF-1 3 A Alleles on HIV-1 Disease Progression: An International seroconverters and seroprevalent patients. In contrast, SDF-1 3 A homozygotes showed no decreased risk for AIDS of HIV-1 infection, but SDF-1 3 A homozygosity carried no such protection. Ann Intern Med. 2001

319

Effect of non-ageing and ageing ceria nanoparticles suspensions on fresh water micro-algae  

E-Print Network [OSTI]

Effect of non-ageing and ageing ceria nanoparticles suspensions on fresh water micro-algae Manier nanoparticle (nCeO2) suspensions, towards freshwater micro-algae assessing the effect nCeO2 suspensions microscopy (TEM). In addition, the interaction between NPs and algae were investigated using flow

Boyer, Edmond

320

Utah Commission on Aging June 16, 2009  

E-Print Network [OSTI]

is focusing on fall prevention, end of life care, and elder abuse issues, all of which fall under the auspices Cherie Brunker Health Care Shauna O'Neil Area Agencies on Aging Robert Archuleta Ethnic Minorities Helen-Michele Church Department of Human Services Kent Alderman Legal Profession Gary Kelso Long-Term Care Jo

Tipple, Brett

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

7, 1365313697, 2007 Global mean age of  

E-Print Network [OSTI]

ACPD 7, 13653­13697, 2007 Global mean age of air from MIPAS G. P. Stiller et al. Title Page measurements G. P. Stiller 1 , T. von Clarmann 1 , M. H¨opfner 1 , N. Glatthor 1 , U. Grabowski 1 , S. Kellmann Correspondence to: G. P. Stiller (gabriele.stiller@imk.fzk.de) 13653 #12;ACPD 7, 13653­13697, 2007 Global mean

Paris-Sud XI, Université de

322

Bitcoin and the Age of Bespoke Silicon  

E-Print Network [OSTI]

Bitcoin and the Age of Bespoke Silicon Michael B. Taylor Associate Professor University of California, San Diego #12;This Talk Introduction An Overview of the Bitcoin Cryptocurrency Bitcoin's Computing Evolution Bespoke Silicon #12;Interesting Facts about Bitcoin The most successful digital

Wang, Deli

323

Aging and Place: Building Health Promotion into  

E-Print Network [OSTI]

Aging and Place: Building Health Promotion into Long-Term Care IHRP Brownbag May 21, 2013 Naoko-being in social contexts. ­ To improve quality of services by building health promotion into long-term care. #12 ­ U.S. 3. Building health promotion into long-term care ­ Why important? ­ Challenges

Illinois at Chicago, University of

324

Stone Age Distributed Computing (Extended Abstract)  

E-Print Network [OSTI]

on the first page. Copyrights for components of this work owned by others than ACM must be honored. AbstractingStone Age Distributed Computing (Extended Abstract) Yuval Emek Distributed Computing Group ETH wattenhofer@ethz.ch ABSTRACT A new model that depicts a network of randomized finite state machines operating

325

Aging assessment of auxiliary feedwater systems  

SciTech Connect (OSTI)

A study of Pressurized Water Reactor Auxiliary Feedwater (AFW) Systems has been conducted by Oak Ridge National Laboratory (ORNL) under the auspices of the Nuclear Regulatory Commission's Nuclear Plant Aging Research Program. The study has reviewed historical failure experience and current monitoring practices for the AFW System. This paper provides an overview of the study approach and results. 7 figs.

Casada, D.A. (Oak Ridge National Lab., TN (USA))

1989-01-01T23:59:59.000Z

326

Eligibility: Cancer Survivor ages 35-75  

E-Print Network [OSTI]

Eligibility: · Cancer Survivor ages 35-75 · Patient has completed treatment within last two years for non-metastic solid tumor · Patient's cancer is currently considered stable or in remission · At least. Please contact Missy Buchanan 415-353-7019 for more information. Helen Diller Family Comprehensive Cancer

Walter, Peter

327

Metabolic reprogramming, caloric restriction and aging  

E-Print Network [OSTI]

metabolic response to changes in nutrient availability, energetic demand or redox status. The fact that many the response to altered nutri- ent availability with CR and how the pathways they regulate can retard the aging and has the potential to reveal cellular pathways that are important in directing

Sheridan, Jennifer

328

Increasing Creel Interview Efficiency Through Early Survey Termination  

E-Print Network [OSTI]

Increasing Creel Interview Efficiency Through Early Survey Termination HAL R. OSBURN and MIKE G were terminated early when no angler interviews were con ducted by a specified time. Using this method, terminating

329

Designing CPV Receivers With Reliability: Early Evaluation of Components  

E-Print Network [OSTI]

. Everett, A. Blakers Centre for Sustainable Energy Systems, The Australian National University, Canberra: Early detection of performance issues allows more rapid & reliable design optimisation. Thermal. Ultra light-weight Fresnel mirror enclosed system. DESIGN RELIABILITY PRODUCTION Early detection

330

Economic Impacts of Early Care and Education in California  

E-Print Network [OSTI]

Economic Impacts of Early Care and Education in California by Jenifer MacGillvary and Laurel Lucia August 2011 #12;#12;Economic Impacts of Early Care and Education in California by Jenifer Mac Siciliano 2 | Economic Impacts of Early Care and Education in California #12;Jenifer MacGillvary and Laurel

Militzer, Burkhard

331

The 2006 Harvard / Paul F. Glenn Symposium on Aging  

E-Print Network [OSTI]

diseases of aging, such as diabetes, cancer, Alzheimer's and heart disease. A recent study1 concluded

Church, George M.

332

Nucleosynthesis in Early Neutrino Driven Winds  

SciTech Connect (OSTI)

Two recent issues related to nucleosynthesis in early proton-rich neutrino winds are investigated. In the first part we investigate the effect of nuclear physics uncertainties on the synthesis of {sup 92}Mo and {sup 94}Mo. Based on recent experimental results, we find that the proton rich winds of the model investigated here can not be the only source of the solar abundance of {sup 92}Mo and {sup 94}Mo. In the second part we investigate the nucleosynthesis from neutron rich bubbles and show that they do not contribute to the nucleosynthesis integrated over both neutron and proton-rich bubbles and proton-rich winds.

Hoffman, R; Fisker, J; Pruet, J; Woosley, S; Janka, H; Buras, R

2008-01-09T23:59:59.000Z

333

Seeing Sound Waves in the Early Universe  

E-Print Network [OSTI]

Temperature and polarization power spectra of the cosmic microwave background can provide essentially incontrovertible evidence for coherent acoustic oscillations in the early universe. A simple model calculation demonstrates explicitly how polarization couples to velocities at the surface of last scatter and is nearly independent of gravitational or density perturbations. For coherent acoustic oscillations, peaks in the temperature and polarization power spectra are precisely interleaved. If observed, such a signal would provide strong support for initial density perturbations on scales larger than the horizon, and thus for inflation.

Arthur Kosowsky

1998-11-10T23:59:59.000Z

334

Quantum Statistical Processes in the Early Universe  

E-Print Network [OSTI]

We show how the concept of quantum open system and the methods in non-equilibrium statistical mechanics can be usefully applied to studies of quantum statistical processes in the early universe. We first sketch how noise, fluctuation, dissipation and decoherence processes arise in a wide range of cosmological problems. We then focus on the origin and nature of noise in quantum fields and spacetime dynamics. We introduce the concept of geometrodynamic noise and suggest a statistical mechanical definition of gravitational entropy. We end with a brief discussion of the theoretical appropriateness to view the physical universe as an open system.

B. L. Hu

1993-02-22T23:59:59.000Z

335

Early Internal and External Dose Magnitude Estimation  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series toESnet4: Networking for the Future of DOE ScienceEarly Edison

336

Early Station Costs Questionnaire | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:YearRound-UpHeat PumpRecord ofESPC ENABLE: ECM Summary ECM Included NotFederal4 - InMaterialEarly

337

EIA - Annual Energy Outlook 2014 Early Release  

Gasoline and Diesel Fuel Update (EIA)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) " ,"Click worksheet9,1,50022,3,,,,6,1,,781 2,328 2,683Diesel prices increaseAEO2014 Early Release Overview

338

EIA - Annual Energy Outlook 2014 Early Release  

Gasoline and Diesel Fuel Update (EIA)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) " ,"Click worksheet9,1,50022,3,,,,6,1,,781 2,328 2,683Diesel prices increaseAEO2014 Early Release

339

Early Childhood Experiences Conference on October 30  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed NewcatalystNeutronEnvironmentZIRKLE FRUIT reducesEarly Career: Emergent Atomic

340

Early steps in the Cold War  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed NewcatalystNeutronEnvironmentZIRKLE FRUIT reducesEarly Career: Emergent...steps in

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Business Model Change in Early-Stage Entrepreneurial Firms Facing High Uncertainty BUSINESS MODEL CHANGE IN EARLY-STAGE ENTREPRENEURIAL  

E-Print Network [OSTI]

Business Model Change in Early-Stage Entrepreneurial Firms Facing High Uncertainty 1 BUSINESS MODEL Business School, U.K. Changing business models is inevitable for early-stage entrepreneurial firms striving in elements of business models in a set of eight early-stage university spin-offs. Findings suggest

Mottram, Nigel

342

Continuous Commissioning in an Aged Office Building  

E-Print Network [OSTI]

ICEBO2005 Cui and Liu Continuous Commissioning SM in an Aged Office Building Y. Cui, Ph.D. Energy Systems Laboratory Architectural Engineering Department University of Nebraska-Lincoln Omaha, NE 68182 cuiy@unomaha.edu Mingsheng Liu, Ph... and Liu Units (AHUs). Among these, 7 AHUs serve the Main Building and Executive Wing areas: one AHU, called Primary AHU, for the perimeter of the Main Building and Executive Wing areas, and six AHUs, called Interior AHUs, for the interior of Main...

Cui, Y.; Liu, M.

2005-01-01T23:59:59.000Z

343

The Sizes of Early-type Galaxies  

E-Print Network [OSTI]

In this letter we present a study of the size luminosity relation of 475 early-type galaxies in the Virgo Cluster with Sloan Digital Sky Survey imaging data. The analysis of our homogeneous, model-independent data set reveals that giant and dwarf early-type galaxies do not form one common sequence in this relation. The dwarfs seem to show weak or no dependence on luminosity, and do not fall on the extension of the rather steep relation of the giants. Under the assumption that the light profile shape varies continuously with magnitude, a curved relation of size and magnitude would be expected. While the galaxies do roughly follow this trend overall, we find that the dwarf galaxies are significantly larger and the low-luminosity giants are significantly smaller than what is predicted. We come to the conclusion that in this scaling relation there is not one common sequence from dwarfs to giants, but a dichotomy which can not be resolved by varying profile shapes. The comparison of our data to a semi-analytic model supports the idea of a physical origin of this dichotomy.

Joachim Janz; Thorsten Lisker

2008-11-20T23:59:59.000Z

344

Critical Dynamics in the Early Universe  

E-Print Network [OSTI]

Methods and concepts for the study of phase transitions mediated by a time-dependent order-parameter field in curved spacetimes are discussed. A practical example is the derivation of an effective (quasi-)potential for the description of `slow-roll' inflation in the early universe. We first summarize our early results on viewing the symmetry behavior of constant background fields in curved but static spacetimes as finite size effect, and the use of derivative expansions for constructing effective actions for slowly-varying background fields. We then introduce the notion of dynamical finite size effect to explain how an exponential expansion of the scale factor imparts a finite size to the system and how the symmetry behavior in de Sitter space can be understood qualitatively in this light. We reason why the exponential inflation can be described equivalently by a scale transformation, thus rendering this special class of dynamics as effectively static. Finally we show how, in this view, one can treat the class of `slow-roll' inflation as a dynamic perturbation off the effectively static class of exponential inflation and understand it as a dynamical critical phenomenon in cosmology.

B. L. Hu

1993-02-22T23:59:59.000Z

345

AGES: THE AGN AND GALAXY EVOLUTION SURVEY  

SciTech Connect (OSTI)

The AGN and Galaxy Evolution Survey (AGES) is a redshift survey covering, in its standard fields, 7.7 deg{sup 2} of the Booetes field of the NOAO Deep Wide-Field Survey. The final sample consists of 23,745 redshifts. There are well-defined galaxy samples in 10 bands (the B{sub W} , R, I, J, K, IRAC 3.6, 4.5, 5.8, and 8.0 {mu}m, and MIPS 24 {mu}m bands) to a limiting magnitude of I < 20 mag for spectroscopy. For these galaxies, we obtained 18,163 redshifts from a sample of 35,200 galaxies, where random sparse sampling was used to define statistically complete sub-samples in all 10 photometric bands. The median galaxy redshift is 0.31, and 90% of the redshifts are in the range 0.085 < z < 0.66. Active galactic nuclei (AGNs) were selected as radio, X-ray, IRAC mid-IR, and MIPS 24 {mu}m sources to fainter limiting magnitudes (I < 22.5 mag for point sources). Redshifts were obtained for 4764 quasars and galaxies with AGN signatures, with 2926, 1718, 605, 119, and 13 above redshifts of 0.5, 1, 2, 3, and 4, respectively. We detail all the AGES selection procedures and present the complete spectroscopic redshift catalogs and spectral energy distribution decompositions. Photometric redshift estimates are provided for all sources in the AGES samples.

Kochanek, C. S. [Department of Astronomy, Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Eisenstein, D. J.; Caldwell, N.; Jones, C.; Murray, S. S.; Forman, W. R.; Green, P. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Cool, R. J. [Department of Astrophysical Sciences, Princeton University, Peyton Hall, Princeton, NJ 08544 (United States); Assef, R. J.; Eisenhardt, P.; Stern, D. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Jannuzi, B. T.; Dey, A. [NOAO, 950 North Cherry Avenue, Tucson, AZ 85719 (United States); Brown, M. J. I. [School of Physics, Monash University, Clayton, Victoria 3800 (Australia); Gonzalez, A. H. [Department of Astronomy, Bryant Space Science Center, University of Florida, Gainesville, FL 32611 (United States)

2012-05-01T23:59:59.000Z

346

Age-dependent decay in the landscape  

E-Print Network [OSTI]

The picture of the "multiverse" arising in diverse cosmological scenarios involves transitions between metastable vacuum states. It was pointed out by Krauss and Dent that the transition rates decrease at very late times, leading to a dependence of the transition probability between vacua on the age of each vacuum region. I investigate the implications of this non-Markovian, age-dependent decay on the global structure of the spacetime in landscape scenarios. I show that the fractal dimension of the eternally inflating domain is precisely equal to 3, instead of being slightly below 3 in scenarios with purely Markovian, age-independent decay. I develop a complete description of a non-Markovian landscape in terms of a nonlocal master equation. Using this description I demonstrate by an explicit calculation that, under some technical assumptions about the landscape, the probabilistic predictions of our position in the landscape are essentially unchanged, regardless of the measure used to extract these predictions. I briefly discuss the physical plausibility of realizing non-Markovian vacuum decay in cosmology in view of the possible decoherence of the metastable quantum state.

Sergei Winitzki

2007-12-14T23:59:59.000Z

347

THE INTERACTING EARLY-TYPE BINARY V382 Cyg  

SciTech Connect (OSTI)

We analyze photometric and spectroscopic data and study the orbital period of the early-type interacting binary system V382 Cyg by using all the available data. We obtain a simultaneous light and radial velocity curve solution. The derived physical parameters of the primary and secondary stellar components are M{sub 1} = 27.9(5) M{sub Sun }, M{sub 2} = 20.8(4) M{sub Sun }, R{sub 1} = 9.7(2) R{sub Sun }, R{sub 2} = 8.5(2) R{sub Sun }, log ({sub 1}/L{sub Sun }) = 5.152(20), and log (L{sub 2}/L{sub Sun }) = 4.954(19) while the separation of the components is a = 23.4 R{sub Sun }. Newly obtained parameters yield the distance of the system to be 1466(76) pc. Analyses of the mid-eclipse times indicate a period increase of dP/dt = 4.2(1) Multiplication-Sign 10{sup -7} days yr{sup -1} that can be interpreted in terms of the high-mass transfer (dM/dt 6.1(5) Multiplication-Sign 10{sup -6} M{sub Sun} yr{sup -1}) from the less massive component to the more massive component. Finally, we model the evolution of the components using non-conservative codes and discuss the results obtained. The age of the binary system is estimated to be 3.85 Myr.

Yasarsoy, B.; Yakut, K. [Department of Astronomy and Space Sciences, University of Ege, 35100 Bornova-Izmir (Turkey)

2013-01-01T23:59:59.000Z

348

Central stellar populations of early-type galaxies in low-density environments  

E-Print Network [OSTI]

We have investigated the properties of a volume and magnitude limited sample of nearby early type galaxies that were carefully selected from the AAO two degree field galaxy redshift survey. We used images from the DSS to confirm the E/S0 morphologies, and augmented this sample with field galaxies from Colbert et al. 2001. We present spectroscopic observations of 22 galaxies from the combined sample, from which central velocity dispersions and the Lick stellar population indices were measured. After carefully correcting the spectra for nebular emission we derived luminosity-weighted ages, metallicities, and alpha-element abundance ratios. We compare these isolated galaxies with samples of early-type galaxies in the Virgo and Coma clusters, and also with the sample of galaxies in low-density regions of Kuntschner et al. (2002). We find that galaxies in low-density environments are younger and have a greater spread of ages compared to cluster galaxies. They also show a wider range of metallicities at a given velocity dispersion than cluster galaxies, which display only super-solar metallicities. On average cluster, as well as, isolated galaxies show non-solar abundance ratios in alpha-elements, suggesting that, independent of galactic environment, star formation occurred on short time-scales. We reason that early-type galaxies in low-density environments experienced merging-induced star-formation episodes over a longer and more recent period of time compared to a cluster environment, and speculate that a considerable fraction of their stars formed out of low-metallicity halo gaseous material during the slow growth of a stellar disk between merging events.

M. Collobert; M. Sarzi; R. L. Davies; H. Kuntschner; Matthew Colless

2006-05-24T23:59:59.000Z

349

E-Print Network 3.0 - apobec3g restricts early Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

complex is then able to ubiquitinate the APOBEC3G factor bound to Vif by its N... HIV Research (2008) 6, 91-99. Key ... Source: Ecole Polytechnique, Centre de mathmatiques...

350

Discovering colorons at the early stage LHC  

SciTech Connect (OSTI)

Prospects are investigated for the discovery of massive hypergluons using data from the early runs of the Large Hadron Collider. A center of mass energy of 7 TeV and an integrated luminosity of 1 fb{sup -1} or 5 fb{sup -1} are assumed. A phenomenological Lagrangian is adopted to evaluate the cross section of a pair of colored vector bosons (colorons, {rho}-tilde) decaying into four colored scalar resonances (hyperpions, {pi}-tilde), which then decay into eight gluons. The dominant eight-jet background from the production of 8g, 7g1q, 6g2q, and 5g3q is included. We find an abundance of signal events and that realistic cuts reduce the background enough to establish a 5{sigma} signal for the coloron mass of up to 733 GeV with 1 fb{sup -1} or 833 GeV with 5 fb{sup -1}.

Dicus, Duane A. [Center for Particles and Fields and Texas Cosmology Center, University of Texas, Austin, Texas 78712 (United States); Kao, Chung; Sayre, Joshua [Homer L. Dodge Department of Physics and Astronomy and Oklahoma Center for High Energy Physics, University of Oklahoma, Norman, Oklahoma 73019 (United States); Nandi, S. [Department of Physics and Oklahoma Center for High Energy Physics, Oklahoma State University, Stillwater, Oklahoma 74078 (United States)

2011-05-01T23:59:59.000Z

351

Preserving Alaska's early Cold War legacy.  

SciTech Connect (OSTI)

The US Air Force owns and operates numerous facilities that were constructed during the Cold War era. The end of the Cold War prompted many changes in the operation of these properties: missions changed, facilities were modified, and entire bases were closed or realigned. The widespread downsizing of the US military stimulated concern over the potential loss of properties that had acquired historical value in the context of the Cold War. In response, the US Department of Defense in 1991 initiated a broad effort to inventory properties of this era. US Air Force installations in Alaska were in the forefront of these evaluations because of the role of the Cold War in the state's development and history and the high interest on the part of the Alaska State Historic Preservation Officer (SHPO) in these properties. The 611th Air Support Group (611 ASG) owns many of Alaska's early Cold War properties, most were associated with strategic air defense. The 611 ASG determined that three systems it operates, which were all part of the integrated defense against Soviet nuclear strategic bomber threat, were eligible for the National Register of Historic Places (NRHP) and would require treatment as historic properties. These systems include the Aircraft Control and Warning (AC&W) System, the Distant Early Warning (DEW) Line, and Forward Operating Bases (FOBs). As part of a massive cleanup operation, Clean Sweep, the 611 ASG plans to demolish many of the properties associated with these systems. To mitigate the effects of demolition, the 611 ASG negotiated agreements on the system level (e.g., the DEW Line) with the Alaska SHPO to document the history and architectural/engineering features associated with these properties. This system approach allowed the US Air Force to mitigate effects on many individual properties in a more cost-effective and efficient manner.

Hoffecker, J.; Whorton, M.

1999-03-08T23:59:59.000Z

352

Breast health problems are rare in both HIV-infected and uninfected women supported to exclusively breastfeed in South Africa  

E-Print Network [OSTI]

to exclusively breastfeed in South Africa RM Bland1,2 , R Becquet1,3,4 , NC Rollins5 , A Coutsoudis5 , HM, Somkhele, South Africa 2 Division of Developmental Medicine, University of Glasgow, UK 3 INSERM, Unité 593Zulu Natal, South Africa 6 Centre for HIV/AIDS Networking, University of KwaZulu Natal, South Africa 7 Centre

Boyer, Edmond

353

Improving the Anti-HIV Potency of Different Compounds through Synergy and Covalent Linkage: Dimerization Studies of CXCL8  

E-Print Network [OSTI]

In the first part of my dissertation we focused on the development of covalently linking compounds that bind gp120 with those that bind gp41 in order to block HIV fusion. We used griffithsin or CD4M33, that both bind to gp120, covalently linked...

Kagiampakis, Ioannis

2011-10-21T23:59:59.000Z

354

Supplementary data for HIV-1 Tat membrane interaction probed using X-ray and neutron scattering, CD, and MD simulations  

E-Print Network [OSTI]

1 Supplementary data for HIV-1 Tat membrane interaction probed using X-ray and neutron scattering- spacing are linearly related. Figure S3. Neutron scattering from stacks of DOPC:DOPE (3:1)/Tat, x=0 of Physics, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, NY 12180, 3 NIST Center for Neutron

Nagle, John F.

355

HIV-1 Tat membrane interactions probed using X-ray and neutron scattering, CD spectroscopy and MD simulations  

E-Print Network [OSTI]

HIV-1 Tat membrane interactions probed using X-ray and neutron scattering, CD spectroscopy and MD translocation, were provided by wide-angle X-ray scattering (WAXS) and neutron scattering. CD spectroscopy for Neutron Research, 100 Bureau Drive, Stop 6102, Gaithersburg, MD 20899, United States d CHESS, Cornell

Nagle, John F.

356

original article The American Society of Gene & Cell Therapy The continued spread of HIV underscores the need to  

E-Print Network [OSTI]

underscores the need to interrupt transmission. One attractive strategy, in the absence of an effectiveCs) targeting the HIV coreceptor CCR5, gag, and vif protected humanized mice from sexual transmission. In nonCs against CCR5 or gag/vif performed as well as a cock- tail in humanized mice. Transmission was completely

Lieberman, Judy

357

Free Energy Component Analysis for Drug Design: A Case Study of HIV-1 Protease-Inhibitor Binding  

E-Print Network [OSTI]

Free Energy Component Analysis for Drug Design: A Case Study of HIV-1 Protease-Inhibitor Binding energy component analysis that conveys information on the physicochemical forces driving the protein for a specific protein target if not in the general case. It is here that the free energy component analysis

Jayaram, Bhyravabotla

358

QSAR de alguns inibidores peptdicos da enzima HIV-1 protease utilizando "a priori" descritores moleculares e molecular graphics  

E-Print Network [OSTI]

moleculares e molecular graphics Rudolf Kiralj (PQ), Márcia Miguel Castro Ferreira (PQ) rudolf-calculator count/calculation using only 1D and 2D chemical formula). A work on COMBINE (COMparative BINding Energy of molecular graphics, are discussed in terms both of the a priori approach and of the HIV-1 protease inhibitor

Ferreira, Márcia M. C.

359

For personal use. Only reproduce with permission from Elsevier Ltd. Most current candidate HIV vaccines seem to produce little  

E-Print Network [OSTI]

vaccines seem to produce little protection against infection, but reduce viral load and slow the decline the following question: could disease-modifying HIV vaccines cause population-level perversity (ie, increase--we show that disease- modifying vaccines that provide only a low degree of protection against infection

Blower, Sally

360

The star formation history of early-type galaxies as a function of mass and environment  

E-Print Network [OSTI]

Using the third data release of the Sloan Digital Sky Survey (SDSS) we have rigorously defined a volume limited sample of early-type galaxies in the redshift range z environment for each galaxy using a method which takes account of the redshift bias introduced by survey boundaries if traditional methods are used. At luminosities greater than our absolute r-band magnitude cutoff of -20.45 the mean density of environment shows no trend with redshift. We calculate the Lick indices for the entire sample and correct for aperture effects and velocity dispersion in a model independent way. Although we find no dependence of redshift or luminosity with environment we do find that the mean velocity dispersion, sigma, of early-type galaxies in dense environments tends to be higher than in low density environments. Taking account of this effect we find that several indices show small but very significant trends with environment that are not the result of the correlation between indices and velocity dispersion. The statistical significance of the data is sufficiently high to reveal that models accounting only for alpha-enhancement struggle to produce a consistent picture of age and metallicity of the sample galaxies, whereas a model that also includes carbon enhancement fares much better. We find that early-type galaxies in the field are younger than those in environments typical of clusters but that neither metallicity, alpha-enhancement nor carbon enhancement are influenced by the environment. The youngest early-type galaxies in both field and cluster environments are those with the lowest sigma. However, there is some evidence that the objects with the largest sigma are slightly younger, especially in denser environments.

M. S. Clemens; A. Bressan; B. Nikolic; P. Alexander; F. Annibali; R. Rampazzo

2006-05-17T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

On the seismic age of the Sun  

E-Print Network [OSTI]

We use low-degree acoustic modes obtained by the BiSON to estimate the main-sequence age $t_\\odot$ of the Sun. The calibration is accomplished by linearizing the deviations from a standard solar model the seismic frequencies of which are close to those of the Sun. Formally, we obtain the preliminary value $t_\\odot=4.68\\pm0.02 $Gy, coupled with an initial heavy-element abundance $Z=0.0169\\pm0.0005$. The quoted standard errors, which are not independent, are upper bounds implied under the assumption that the standard errors in the observed frequencies are independent.

G. Houdek; D. O. Gough

2007-10-03T23:59:59.000Z

362

Rock of Ages | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revisionEnvReviewNonInvasiveExplorationUT-g Grant ofRichardton Abbey Wind Farm It is classified asOpenAges Jump

363

AGE UFMG Incubator | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 NoPublic Utilities Address: 160 East 300 SouthWater Rights,Information OfOpen EnergyEnergyAGE UFMG Incubator Jump

364

Detection of erythrocytes influenced by aging and type 2 diabetes using atomic force microscope  

SciTech Connect (OSTI)

The pathophysiological changes of erythrocytes are detected at the molecular scale, which is important to reveal the onset of diseases. Type 2 diabetes is an age-related metabolic disorder with high prevalence in elderly (or old) people. Up to now, there are no treatments to cure diabetes. Therefore, early detection and the ability to monitor the progression of type 2 diabetes are very important for developing effective therapies. Type 2 diabetes is associated with high blood glucose in the context of insulin resistance and relative insulin deficiency. These abnormalities may disturb the architecture and functions of erythrocytes at molecular scale. In this study, the aging- and diabetes-induced changes in morphological and biomechanical properties of erythrocytes are clearly characterized at nanometer scale using atomic force microscope (AFM). The structural information and mechanical properties of the cell surface membranes of erythrocytes are very important indicators for determining the healthy, diseased or aging status. So, AFM may potentially be developed into a powerful tool in diagnosing diseases.

Jin, Hua; Xing, Xiaobo [Chemistry Department, Jinan University, Guangzhou 510632 (China)] [Chemistry Department, Jinan University, Guangzhou 510632 (China); Zhao, Hongxia [Chemistry Department, Jinan University, Guangzhou 510632 (China) [Chemistry Department, Jinan University, Guangzhou 510632 (China); Faculty of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510090 (China); Chen, Yong [Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330031 (China)] [Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330031 (China); Huang, Xun [Chemistry Department, Jinan University, Guangzhou 510632 (China)] [Chemistry Department, Jinan University, Guangzhou 510632 (China); Ma, Shuyuan [Chemistry Department, Jinan University, Guangzhou 510632 (China) [Chemistry Department, Jinan University, Guangzhou 510632 (China); The First Affiliated Hospital, Jinan University, Guangzhou 510632 (China); Ye, Hongyan [Chemistry Department, Jinan University, Guangzhou 510632 (China)] [Chemistry Department, Jinan University, Guangzhou 510632 (China); Cai, Jiye, E-mail: tjycai@jnu.edu.cn [Chemistry Department, Jinan University, Guangzhou 510632 (China)] [Chemistry Department, Jinan University, Guangzhou 510632 (China)

2010-01-22T23:59:59.000Z

365

Microstructural Features in Aged Erbium Tritide Foils  

SciTech Connect (OSTI)

Aged erbium tritide foil specimens are found to contain five distinctly different microstructural features. The general structure was of large columnar grains of ErT2. But on a fine scale, precipitates believed to be erbium oxy-tritides and helium bubbles could be identified. The precipitate size was in the range of ~10 nm and the bubbles were of an unusual planar shape on {111} planes with an invariant thickness of ~1 nm and a diameter on the order of 10 nm. Also, an outer layer containing no fine precipitate structure and only a few helium bubbles was present on foils. This layer is best described as a denuded zone which probably grew during aging in air. Finally, large embedded Er2O3 particles were found at low density and non-uniformly distributed, but sometimes extending through the thickness of the foil. A failure mechanism allowing the helium to escape is suggested by observed cracking between bubbles closer to end of life.

Gelles, David S.; Brewer, L. N.; Kotula, Paul G.; Cowgill, Donald F.; Busick, C. C.; Snow, C. S.

2008-01-01T23:59:59.000Z

366

SEECAL: Program to calculate age-dependent  

SciTech Connect (OSTI)

This report describes the computer program SEECAL, which calculates specific effective energies (SEE) to specified target regions for ages newborn, 1 y, 5 y, 10 y, 15 y, a 70-kg adult male, and a 58-kg adult female. The dosimetric methodology is that of the International Commission on Radiological Protection (ICRP) and is generally consistent with the schema of the Medical Internal Radiation Dose committee of the US Society of Nuclear Medicine. Computation of SEEs is necessary in the computation of equivalent dose rate in a target region, for occupational or public exposure to radionuclides taken into the body. Program SEECAL replaces the program SEE that was previously used by the Dosimetry Research Group at Oak Ridge National Laboratory. The program SEE was used in the dosimetric calculations for occupational exposures for ICRP Publication 30 and is limited to adults. SEECAL was used to generate age-dependent SEEs for ICRP Publication 56, Part 1. SEECAL is also incorporated into DCAL, a radiation dose and risk calculational system being developed for the Environmental Protection Agency. Electronic copies of the program and data files and this report are available from the Radiation Shielding Information Center at Oak Ridge National Laboratory.

Cristy, M.; Eckerman, K.F.

1993-12-01T23:59:59.000Z

367

Age Dating of Mixed SNM--Preliminary Investigations  

SciTech Connect (OSTI)

Recently we investigated the nuclear forensics problem of age determination for mixed special nuclear material (SNM). Through limited computational mixing experiments and interactive age analysis, it was observed that age dating results are generally affected by the mixing of samples with different assays or even by small radioactive material contamination. The mixing and contamination can be detected through interactive age analysis, a function provided by the Decay Interaction, Visualization and Analysis (DIVA) software developed by NSTec. It is observed that for mixed SNM with two components, the age estimators typically fall into two distinct clusters on the time axis. This suggests that averaging or other simple statistical methods may not always be suitable for age dating SNM mixtures. Instead, an interactive age analysis would be more suitable for age determination of material components of such SNM mixtures. This work was supported by the National Center for Nuclear Security (NCNS).

Yuan, D., Guss, P. P., Yfantis, E., Klingensmith, A., Emer, D.

2011-12-01T23:59:59.000Z

368

Managing Aging Effects on Dry Cask Storage Systems for Extended...  

Office of Environmental Management (EM)

Managing Aging Effects on Dry Cask Storage Systems for Extended Long Term Storage and Transportation of Used Fuel Rev0 Managing Aging Effects on Dry Cask Storage Systems for...

369

Characterization of thermal aging of duplex stainless steel by SQUID  

SciTech Connect (OSTI)

Thermal aging is a growing concern for long-term-aged duplex stainless steel piping in nuclear power plants. Superconducting QUantum Interference Device (SQUID) was used for the detection of thermal aging of SUS329 rolled duplex stainless steel and SCS16 cast duplex stainless steel. It was found that the SQUID output signal pattern in the presence of AC magnetic field applied to the specimen was sensitive to the changes in electromagnetic properties due to thermal aging.

Isobe, Y.; Kamimura, A.; Aoki, K.; Nakayasu, F. [Nuclear Fuel Industries, Ltd., Osaka (Japan)

1995-08-01T23:59:59.000Z

370

AGE: a distributed environment for creating interactive animations of graphs  

E-Print Network [OSTI]

com- munication domain. Standard routines, which we shall refer to as the AGE client primitives, that read snd write AGE messages to and from the socket, and routines that create and interpret AGE messages have been developed and are available... for use by those wishing to code a client program (refer to Appendix C). While most requirements for the environment desired are fulfilled by the AGE server, itself, some facilities are supplied by clients, namely, scripts, view broadcasting...

Veatch, Timothy Richard

1990-01-01T23:59:59.000Z

371

The 2008 Harvard / Paul F. Glenn Symposium on Aging  

E-Print Network [OSTI]

of aging such as diabetes, cancer, Alzheimer's and heart disease. Thus, a major goal in the coming years

Church, George M.

372

The 2007 Harvard / Paul F. Glenn Symposium on Aging  

E-Print Network [OSTI]

are regulated, leading to novel medicines to forestall and treat diseases of aging such as diabetes, cancer

Church, George M.

373

The 2009 Harvard / Paul F. Glenn Symposium on Aging  

E-Print Network [OSTI]

of aging such as diabetes, cancer, Alzheimer's and heart disease. Thus, a major goal in the coming years

Church, George M.

374

COMFEN Early Design Tool for Commercial Facades and Fenestration Systems  

E-Print Network [OSTI]

COMFEN ­ Early Design Tool for Commercial Facades and Fenestration Systems Stephen Selkowitz Sustainable IQ, Inc. Building Technologies Department Environmental Energy Technologies Division CEC PIER

375

Economy and Rhetoric of Exchange in Early Modern Spain  

E-Print Network [OSTI]

Elliott, J. H. Imperial Spain 1469-1716. London: Penguin,2002. ---. Spain and its World 1500-1700. New Haven andin Early Seventeenth- Century Spain. Lewisburg: Bucknell UP,

Ruiz, Eduardo German

2010-01-01T23:59:59.000Z

376

Predictors of Help Seeking Among Early Adolescents: Stages and Factors.  

E-Print Network [OSTI]

??The present study examined mental health help seeking among early adolescents. Drawing from past research (Andersen & Newman, 1973; Andersen, 1995; Srebnik, Cauce, & Baydar, (more)

Bates, Lindsay

2010-01-01T23:59:59.000Z

377

Reflective Terahertz Imaging for early diagnosis of skin burn severity  

E-Print Network [OSTI]

the brand area is also visualized in the THz images of thebrand shape is discernible as early as the post burn THz image.

TEWARI, PRIYAMVADA

2013-01-01T23:59:59.000Z

378

adenovirus early gene: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors CiteSeer Summary: Systemic application of...

379

adenovirus early antigens: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors CiteSeer Summary: Systemic application of...

380

Fission track evidence for widespread early to Middle miocene...  

Open Energy Info (EERE)

and Range province Jump to: navigation, search OpenEI Reference LibraryAdd to library Conference Proceedings: Fission track evidence for widespread early to Middle miocene...

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Virtual Age: Enabling Technologies and Trends Hamid Mahmoodi 1  

E-Print Network [OSTI]

. This much-needed breakthrough manifested itself in the form of the industrial revolution. Industrial revolution signaled the end of the Agricultural Age and moved the human society forward towards the Industrial Age which lasted for about 500 years. In this age, great inventions, such as, the steam engine

Mahmoodi, Hamid

382

FUNCTIONAL ESTIMATION FOR A MULTICOMPONENT AGE REPLACEMENT MODEL  

E-Print Network [OSTI]

1 FUNCTIONAL ESTIMATION FOR A MULTICOMPONENT AGE REPLACEMENT MODEL Pierre L'Ecuyer, Benoit Martin, controlled by a replacement rule based on age thresholds. We show how to estimate the expected cost­ generative simulation, maintenance models, age replacement policies. #12; 2 L'ECUYER, MARTIN, AND V ' AZQUEZ

L'Ecuyer, Pierre

383

FUNCTIONAL ESTIMATION FOR A MULTICOMPONENT AGE REPLACEMENT MODEL  

E-Print Network [OSTI]

FUNCTIONAL ESTIMATION FOR A MULTICOMPONENT AGE REPLACEMENT MODEL Pierre L'Ecuyer, Benoit Martin, controlled by a replacement rule based on age thresholds. We show how to estimate the expected cost­ generative simulation, maintenance models, age replacement policies. #12; L'ECUYER, MARTIN, AND V ' AZQUEZ

Vázquez-Abad, Felisa J.

384

Risky Subjectivity : : The Effects of Cultural Discourses of Addiction on Methamphetamine Using HIV+ Men Who Have Sex with Men in San Diego  

E-Print Network [OSTI]

27, 2013. Burroway, Jim Is MRSA The New Gay Plague? Nothttp://www.boxturtlebulletin.com/is-mrsa-the-new-gay-plague.s HIV- based motives, the MRSA outbreaks in the mid 2000s (

Gideonse, Theodore Karwoski

385

Young peoples perspectives on the adoption of preventive measures for HIV/AIDS, malaria and family planning in South-West Uganda: focus group study  

E-Print Network [OSTI]

Abstract Background Despite the possibility of preventing many cases of HIV, malaria and unplanned pregnancy, protective measures are often not taken by those at risk in Uganda. The study aim was to explore young peoples perspectives...

Graffy, Jonathan; Goodhart, Clare; Sennett, Karen; Kamusiime, Gloria; Tukamushaba, Herbert

2012-11-22T23:59:59.000Z

386

Use of retroviral peptide libraries for the identification of novel cellular targets of HIV-1 and the discovery of novel inhibitors  

E-Print Network [OSTI]

of PR, inserted between the DBD and TAD domains inhibits GFPtrans-activation domain (TAD) separated by HIV-1 PR underfusion, separating the DBD and TAD domains, both of which

Stotland, Aleksandr Borisovich; Stotland, Aleksandr Borisovich

2012-01-01T23:59:59.000Z

387

POLICY ON HIV DISEASE AND AIDS It is the intent of this policy to ensure that those individuals living with the Human Immunodeficiency  

E-Print Network [OSTI]

POLICY ON HIV DISEASE AND AIDS It is the intent of this policy to ensure that those individuals who feels discriminated against or who has a policy related question should contact the Office

Bolding, M. Chad

388

What makes some campaigns more effective than others?: An analysis of three mass media PSI HIV/AIDS campaigns in Kenya.  

E-Print Network [OSTI]

This study included interviews with campaign planners at a major social marketing organization in Kenya and an examination of three comprehensive HIV/AIDS health campaigns produced by the planners. Thematic and qualitative content analysis...

Mabachi, Natabhona Marianne

2008-12-15T23:59:59.000Z

389

Mechanism study of a small molecule F18 as a novel anti-HIV-1 non-nucleoside reverse transcriptase inhibitor.  

E-Print Network [OSTI]

???Non-nucleoside reverse transcriptase inhibitor (NNRTI) is one of the key components of antiretroviral drug regimen against human immunodeficiency virus type-1 (HIV-1) replication. However, the low (more)

???.

2012-01-01T23:59:59.000Z

390

EARLY EMISSION FROM TYPE Ia SUPERNOVAE  

SciTech Connect (OSTI)

A unique feature of deflagration-to-detonation (DDT) white dwarf explosion models of supernovae of type Ia is the presence of a strong shock wave propagating through the outer envelope. We consider the early emission expected in such models, which is produced by the expanding shock-heated outer part of the ejecta and precedes the emission driven by radioactive decay. We expand on earlier analyses by considering the modification of the pre-detonation density profile by the weak shocks generated during the deflagration phase, the time evolution of the opacity, and the deviation of the post-shock equation of state from that obtained for radiation pressure domination. A simple analytic model is presented and shown to provide an acceptable approximation to the results of one-dimensional numerical DDT simulations. Our analysis predicts a {approx}10{sup 3} s long UV/optical flash with a luminosity of {approx}1 to {approx}3 Multiplication-Sign 10{sup 39} erg s{sup -1}. Lower luminosity corresponds to faster (turbulent) deflagration velocity. The luminosity of the UV flash is predicted to be strongly suppressed at t > t{sub drop} {approx} 1 hr due to the deviation from pure radiation domination.

Rabinak, Itay; Waxman, Eli [Department of Particle Physics and Astrophysics, Weizmann Institute of Science, Rehovot 76100 (Israel); Livne, Eli, E-mail: itay.rabinak@weizmann.ac.il [Racah Institute of Physics, Hebrew University, Jerusalem (Israel)

2012-09-20T23:59:59.000Z

391

Dark Energy in the Dark Ages  

E-Print Network [OSTI]

Non-negligible dark energy density at high redshifts would indicate dark energy physics distinct from a cosmological constant or ``reasonable'' canonical scalar fields. Such dark energy can be constrained tightly through investigation of the growth of structure, with limits of \\la2% of total energy density at z\\gg1 for many models. Intermediate dark energy can have effects distinct from its energy density; the dark ages acceleration can be constrained to last less than 5% of a Hubble e-fold time, exacerbating the coincidence problem. Both the total linear growth, or equivalently \\sigma_8, and the shape and evolution of the nonlinear mass power spectrum for zenergy behavior over the entire range z=0-1100.

Eric V. Linder

2006-04-11T23:59:59.000Z

392

Ageing of Natural Rubber under Stress  

E-Print Network [OSTI]

We report a dynamical-mechanical study of stress relaxation at small deformation in a natural (polyisoprene) rubber well above its glass transition temperature Tg. We find that an almost complete relaxation of stress takes place over very long periods of time, even though the elastic network integrity is fully retained. The relaxation rate and the long-time equilibrium modulus are sensitive functions of temperature which do not follow time-temperature superposition. Many characteristic features of non-ergodic ageing response are apparent at both short and very long times. We interpret the observed behaviour in terms of the properties of rubber crosslinks, capable of isomerisation under stress, and relate the results to recent models of soft glassy rheology.

S. M. Clarke; F. Elias; E. M. Terentjev

2000-05-04T23:59:59.000Z

393

Evaluation of aging degradation of structural components  

SciTech Connect (OSTI)

Irradiation embrittlement of the neutron shield tank (NST) A212 Grade B steel from the Shippingport reactor, as well as thermal embrittlement of CF-8 cast stainless steel components from the Shippingport and KRB reactors, has been characterized. Increases in Charpy transition temperature (CTT), yield stress, and hardness of the NST material in the low-temperature low-flux environment are consistent with the test reactor data for irradiations at < 232{degrees}C. The shift in CTT is not as severe as that observed in surveillance samples from the High Flux Isotope Reactor (HFIR): however, it shows very good agreement with the results for HFIR A212-B steel irradiated in the Oak Ridge Research Reactor. The results indicate that fluence rate has not effect on radiation embrittlement at rates as low as 2 {times} 10{sup 8} n/cm{sup 2}{center_dot}s at the low operating temperature of the Shippingport NST, i.e., 55{degrees}C. This suggest that radiation damage in Shippingport NST and HFIR surveillance samples may be different because of the neutron spectra and/or Cu and Ni content of the two materials. Cast stainless steel components show relatively modest decreases in fracture toughness and Charpy-impact properties and a small increase in tensile strength. Correlations for estimating mechanical properties of cast stainless steels predict accurate or slightly conservative values for Charpy-impact energy, tensile flow stress, fracture toughness J-R curve, and J{sub IC} of the materials. The kinetics of thermal embrittlement and degree of embrittlement at saturation, i.e., the minimum impact energy achieved after long-term aging, were established from materials that were aged further in the laboratory. The results were consistent with the estimates. The correlations successfully predict the mechanical properties of the Ringhals 2 reactor hot- and crossover-leg elbows (CF-8M steel) after service of {approx}15 y.

Chopra, O.K.; Shack, W.J.

1992-03-01T23:59:59.000Z

394

Evaluation of aging degradation of structural components  

SciTech Connect (OSTI)

Irradiation embrittlement of the neutron shield tank (NST) A212 Grade B steel from the Shippingport reactor, as well as thermal embrittlement of CF-8 cast stainless steel components from the Shippingport and KRB reactors, has been characterized. Increases in Charpy transition temperature (CTT), yield stress, and hardness of the NST material in the low-temperature low-flux environment are consistent with the test reactor data for irradiations at < 232{degrees}C. The shift in CTT is not as severe as that observed in surveillance samples from the High Flux Isotope Reactor (HFIR): however, it shows very good agreement with the results for HFIR A212-B steel irradiated in the Oak Ridge Research Reactor. The results indicate that fluence rate has not effect on radiation embrittlement at rates as low as 2 {times} 10{sup 8} n/cm{sup 2}{center dot}s at the low operating temperature of the Shippingport NST, i.e., 55{degrees}C. This suggest that radiation damage in Shippingport NST and HFIR surveillance samples may be different because of the neutron spectra and/or Cu and Ni content of the two materials. Cast stainless steel components show relatively modest decreases in fracture toughness and Charpy-impact properties and a small increase in tensile strength. Correlations for estimating mechanical properties of cast stainless steels predict accurate or slightly conservative values for Charpy-impact energy, tensile flow stress, fracture toughness J-R curve, and J{sub IC} of the materials. The kinetics of thermal embrittlement and degree of embrittlement at saturation, i.e., the minimum impact energy achieved after long-term aging, were established from materials that were aged further in the laboratory. The results were consistent with the estimates. The correlations successfully predict the mechanical properties of the Ringhals 2 reactor hot- and crossover-leg elbows (CF-8M steel) after service of {approx}15 y.

Chopra, O.K.; Shack, W.J.

1992-03-01T23:59:59.000Z

395

aging management guideline: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

lack adequate early- and late-seral forest habitat to meet this goal. Sustainable forestry practices can provide earlyseral forest habitat while addressing increasing societal...

396

Aging management guideline for commercial nuclear power plants - heat exchangers  

SciTech Connect (OSTI)

This Aging Management Guideline (AMG) describes recommended methods for effective detection and mitigation of age-related degradation mechanisms in commercial nuclear power plant heat exchangers important to license renewal. The intent of this AMG is to assist plant maintenance and operations personnel in maximizing the safe, useful life of these components. It also supports the documentation of effective aging management programs required under the License Renewal Rule 10 CFR 54. This AMG is presented in a manner that allows personnel responsible for performance analysis and maintenance to compare their plant-specific aging mechanisms (expected or already experienced) and aging management program activities to the more generic results and recommendations presented herein.

Booker, S.; Lehnert, D.; Daavettila, N.; Palop, E.

1994-06-01T23:59:59.000Z

397

Early Termination in Sparse Interpolation Erich Kaltofen a  

E-Print Network [OSTI]

Early Termination in Sparse Interpolation Algorithms Erich Kaltofen a , Wen-shin Lee b a termination, enables different interpolation algo- rithms to adapt to the degree or the number of terms this strategy in sparse interpolation algorithms. Based on early termination, racing algorithms execute

Kaltofen, Erich

398

ORIGINAL ARTICLE Early Brain Overgrowth in Autism Associated  

E-Print Network [OSTI]

ORIGINAL ARTICLE Early Brain Overgrowth in Autism Associated With an Increase in Cortical Surface, PhD; Chad Chappell, MA; Rachel Gimpel Smith, BA; Clement Vachet, MS; Joseph Piven, MD Context: Brain. Objective: To investigate early growth trajectories in brain volume and cortical thickness. Design

Utah, University of

399

Early Solar System Chronology K.D. McKeegan  

E-Print Network [OSTI]

, and to a first approximation can be thought of as ``hand samples'' of the condensable portion of the solar nebula1.16 Early Solar System Chronology K.D. McKeegan University of California, Los Angeles, CA, USA Meteorites as Probes of Early Solar System Evolution 2 1.16.1.2 Short-Lived Radioactivity at the Origin

Reiners, Peter W.

400

Directory of Early Michigan Photographers David V. Tinder  

E-Print Network [OSTI]

Directory of Early Michigan Photographers David V. Tinder Edited by Clayton A. Lewis Copyright, University of Michigan, Ann Arbor Online edition updated December 2013. #12;The Directory of Early Michigan for directories of this type. While a dearth of information has kept some entries brief, the lives of many have

Edwards, Paul N.

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

2011 ECTC Proceedings ASME Early Career Technical Conference  

E-Print Network [OSTI]

2011 ECTC Proceedings ASME Early Career Technical Conference Hosted by ASME District E and University of Arkansas Support Provided by the ASME Old Guard and the Committee on Early Career Development and power industries. The two phase flow has been proven economical in the laying of the oil and natural gas

Ghajar, Afshin J.

402

On the Early Tension between String Theory and Phenomenology  

E-Print Network [OSTI]

On the Early Tension between String Theory and Phenomenology L. Clavelli Department of Physics noticeable tension between string theory and phenomenology in particle physics. It is interesting to muse theory and phenomenology is more easily understandable than that of the early days. Today it is primarily

Clavelli, Louis J.

403

Ecological Energetics in Early Homo Author(s): Herman Pontzer  

E-Print Network [OSTI]

Ecological Energetics in Early Homo Author(s): Herman Pontzer Reviewed work(s): Source: Current new forms of scholarship. For more information about JSTOR, please contact support.00. DOI: 10.1086/667402 Ecological Energetics in Early Homo by Herman Pontzer CA Online-Only Material

Pontzer, Herman

404

A Review of "New World Gold: Cultural Anxiety and Monetary Disorder in Early Modern Spain" by Elvira Vilches  

E-Print Network [OSTI]

) and the Dominican Tom?s Mercado?s Suma de tratos y contratos (Guide to negotiations and contracts, 1569). Not unlike the bumper crop of books on personal finance that have ap- peared since our own economic meltdown of 2008, the proliferation of such texts... of Columbus?s travel log or Cort?s?s ?Letters from Mexico.? Whether read in parts or as a whole, Vilches?s book offers the reader a layered and insightful examination of early modern Spain?s ?Golden Age,? attune to all the contradictions that follow from...

Wright, Elizabeth R.

2011-01-01T23:59:59.000Z

405

Rapid prototyping is coming of age  

SciTech Connect (OSTI)

This article examines how, by accelerating the design process and speeding tooling development, rapid prototyping technology helps manufacturers cut new product cycle times and costs. During the last decade, a class of technologies has emerged by which a computer-aided design file of an object can be converted into a physical model through special sintering, layering, or deposition techniques. Called rapid prototyping (RP), or solid free-form fabrication, the major application for this technology has been early verification of product designs and quick production of prototypes for testing. Multiple prototypes can now be reproduced more economically by using the RP master as a pattern for creating molded or soft tooling. Interest in desktop (or more accurately, office) rapid prototyping for visualization and design verification is growing, but it is not yet easy to cost-justify. Recently, the fabrication of patterns for limited-run production tooling has become more common. Today, the most popular rapid tooling options are silicone rubber (RTV) molding and epoxy and spray metal tooling. For metal part production, the choices are investment, plaster, spin, and sand casting.

Ashley, S.

1995-07-01T23:59:59.000Z

406

Element Abundances through the Cosmic Ages  

E-Print Network [OSTI]

The horizon for studies of element abundances has expanded dramatically in the last ten years. Once the domain of astronomers concerned chiefly with stars and nearby galaxies, this field has now become a key component of observational cosmology, as technological advances have made it possible to measure the abundances of several chemical elements in a variety of environments at redshifts up to z = 4, when the universe was in its infancy. In this series of lectures I summarise current knowledge on the chemical make-up of distant galaxies observed directly in their starlight, and of interstellar and intergalactic gas seen in absorption against the spectra of bright background sources. The picture which is emerging is one where the universe at z = 3 already included many of the constituents of today's galaxies-even at these early times we see evidence for Population I and II stars, while the `smoking gun' for Population III objects may be hidden in the chemical composition of the lowest density regions of the intergalactic medium, yet to be deciphered.

Max Pettini

2003-03-12T23:59:59.000Z

407

IS ACTIVE REGION CORE VARIABILITY AGE DEPENDENT?  

SciTech Connect (OSTI)

The presence of both steady and transient loops in active region cores has been reported from soft X-ray and extreme-ultraviolet observations of the solar corona. The relationship between the different loop populations, however, remains an open question. We present an investigation of the short-term variability of loops in the core of two active regions in the context of their long-term evolution. We take advantage of the nearly full Sun observations of STEREO and Solar Dynamics Observatory spacecraft to track these active regions as they rotate around the Sun multiple times. We then diagnose the variability of the active region cores at several instances of their lifetime using EIS/Hinode spectral capabilities. We inspect a broad range of temperatures, including for the first time spatially and temporally resolved images of Ca XIV and Ca XV lines. We find that the active region cores become fainter and steadier with time. The significant emission measure at high temperatures that is not correlated with a comparable increase at low temperatures suggests that high-frequency heating is viable. The presence, however, during the early stages, of an enhanced emission measure in the ''hot'' (3.0-4.5 MK) and ''cool'' (0.6-0.9 MK) components suggests that low-frequency heating also plays a significant role. Our results explain why there have been recent studies supporting both heating scenarios.

Ugarte-Urra, Ignacio [College of Science, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States); Warren, Harry P. [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States)

2012-12-10T23:59:59.000Z

408

Stabilizing Soybean Production in Northeast Texas with Early Planting of Early-Maturing Soybean Varieties.  

E-Print Network [OSTI]

a pro longed hot, dry period in July and August, coinciding with the blooming and seed-filling periods of Maturity Groups (MG) V, VI, and VII soybean varieties planted in Mayor early June, which are harvested in October. This traditional soybean... systems/ North east Texas/ yield. rizes the results [rom a 3-year study comparing the agro nom.ic ~rformance of MG III and IV varieties planted in Apnl WIth MG V, VI, and VII varieties planted in May. Materials and Methods Test plots were located...

Bowers, G.R. Jr; Nelson, L.R.; Finch, G.A. III

1990-01-01T23:59:59.000Z

409

Early Detection of Steel Rebar Corrosion by Acoustic Emission Monitoring Early Detection of Steel Rebar Corrosion by Acoustic Emission  

E-Print Network [OSTI]

Early Detection of Steel Rebar Corrosion by Acoustic Emission Monitoring Early Detection of Steel Rebar Corrosion by Acoustic Emission Monitoring Alan D. Zdunek and David Prine BIRL Industrial Research, Evanston, IL 60201 Paper No. 547 presented at CORROSION95, the NACE International Annual Conference

410

ICES/PICES Early Career Scientists Symposium Marine science with global vision: creating a place for early career  

E-Print Network [OSTI]

the 2007 Early Career Scientists Conference. ­ ICES Journal of Marine Science, 66: 334­335. Received 30 as the international organizations tasked with fostering marine science and applying it to the wise stewardship of their results to the international com- munity. The Early Career Scientists Conference (ECSC) "New Frontiers

North, Elizabeth W.

411

Integrated Diagnostic and Prognostic Tools for Residual Life Estimation in Aging Nuclear Power Plant Components  

SciTech Connect (OSTI)

Recent events in Japan have focused renewed attention on the safe operation of light water reactor (LWR) nuclear power plants (NPPs). A central issue in safe, long-term operations of existing and planned NPPs is the early detection and monitoring of significant materials degradation. Materials aging and degradation in passive components is expected to be the key factor in determining the operational life of an NPP and may limit long-term operations in the current LWR fleet. Methods for detecting and assessing the degradation state in NPP structural materials, followed by approaches to estimate the remaining useful life (RUL) of the component, are therefore necessary for safe, long-term operations. This paper explores advanced diagnostic and prognostic approaches to detecting material degradation, and then determining RUL given the current material state.

Ramuhalli, Pradeep; Meyer, Ryan M.; Bond, Leonard J.; Griffin, Jeffrey W.; Henager, Charles H.

2011-06-01T23:59:59.000Z

412

Early Market TRL/MRL Analysis  

SciTech Connect (OSTI)

he focus of this report is TRL/MRL analysis of hydrogen storage; it documents the methodology and results of an effort to identify hydrogen storage technologies technical and manufacturing readiness for early market motive and non-motive applications and to provide a path forward toward commercialization. Motive applications include materials handling equipment (MHE) and ground support equipment (GSE), such as forklifts, tow tractors, and specialty vehicles such as golf carts, lawn mowers and wheel chairs. Non-motive applications are portable, stationary or auxiliary power units (APUs) and include portable laptops, backup power, remote sensor power, and auxiliary power for recreational vehicles, hotels, hospitals, etc. Hydrogen storage technologies assessed include metal hydrides, chemical hydrides, sorbents, gaseous storage, and liquid storage. The assessments are based on a combination of Technology Readiness Level (TRL) and Manufacturing Readiness Level (MRL) designations that enable evaluation of hydrogen storage technologies at varying levels of development. The manufacturing status could be established from eight risk elements: Technical Maturity, Design, Materials, Cost & Funding, Process Capability, Personnel, Facilities and Manufacturing Planning. This approach provides a logical methodology and roadmap to enable the identification of hydrogen storage technologies, their advantages/disadvantages, gaps and R&D needs on an unbiased and transparent scale that is easily communicated to interagency partners. This technology readiness assessment (TRA) report documents the process used to conduct the TRA/MRA (technology and manufacturing readiness assessment), reports the TRL and MRL for each assessed technology and provides recommendations based on the findings. To investigate the state of the art and needs to mature the technologies, PNNL prepared a questionnaire to assign TRL and MRL for each hydrogen storage technology. The questionnaire was sent to identified hydrogen storage technology developers and manufacturers who were asked to perform a self-assessment. We included both domestic and international organizations including U.S. national laboratories, U.S. companies, European companies and Japanese companies. PNNL collected the data and performed an analysis to deduce the level of maturity and to provide program recommendations.

Ronnebro, Ewa; Stetson, Ned

2013-12-01T23:59:59.000Z

413

LIGA microsystems aging : evaluation and mitigation.  

SciTech Connect (OSTI)

The deployment of LIGA structures in DP applications requires a thorough understanding of potential long term physical and chemical changes that may occur during service. While these components are generally fabricated from simple metallic systems such as copper, nickel and nickel alloys, the electroplating process used to form them creates microstructural features which differ from those found in conventional (e.g. ingot metallurgy) processing of such materials. Physical changes in non-equilibrium microstructures may occur due to long term exposure to temperatures sufficient to permit atomic and vacancy mobility. Chemical changes, particularly at the surfaces of LIGA parts, may occur in the presence of gaseous chemical species (e.g. water vapor, HE off-gassing compounds) and contact with other metallic structures. In this study, we have characterized the baseline microstructure of several nickel-based materials that are used to fabricate LIGA structures. Solute content and distribution was found to have a major effect on the electroplated microstructures. Microstructural features were correlated to measurements of hardness and tensile strength. Dormancy testing was conducted on one of the baseline compositions, nickel-sulfamate. Groups of specimens were exposed to controlled thermal cycles; subsequent examinations compared properties of 'aged' specimens to the baseline conditions. Results of our testing indicate that exposure to ambient temperatures (-54 C to 71 C) do not result in microstructural changes that might be expected to significantly effect mechanical performance. Additionally, no localized changes in surface appearance were found as a result of contact between electroplated parts.

Cadden, Charles H.; Yang, Nancy Y. C.; San Marchi, Christopher W.

2003-12-01T23:59:59.000Z

414

Aging and weathering of cool roofing membranes  

SciTech Connect (OSTI)

Aging and weathering can reduce the solar reflectance of cool roofing materials. This paper summarizes laboratory measurements of the solar spectral reflectance of unweathered, weathered, and cleaned samples collected from single-ply roofing membranes at various sites across the United States. Fifteen samples were examined in each of the following six conditions: unweathered; weathered; weathered and brushed; weathered, brushed and then rinsed with water; weathered, brushed, rinsed with water, and then washed with soap and water; and weathered, brushed, rinsed with water, washed with soap and water, and then washed with an algaecide. Another 25 samples from 25 roofs across the United States and Canada were measured in their unweathered state, weathered, and weathered and wiped. We document reduction in reflectivity resulted from various soiling mechanisms and provide data on the effectiveness of various cleaning approaches. Results indicate that although the majority of samples after being washed with detergent could be brought to within 90% of their unweathered reflectivity, in some instances an algaecide was required to restore this level of reflectivity.

Akbari, Hashem; Berhe, Asmeret A.; Levinson, Ronnen; Graveline,Stanley; Foley, Kevin; Delgado, Ana H.; Paroli, Ralph M.

2005-08-23T23:59:59.000Z

415

A crossfield literature review of the HIV and AIDS impacts on the Ugandan workforce through the HRD lens  

E-Print Network [OSTI]

, INGO effectiveness assessments, development of instruments for measuring outputs upon the workforce environment, and workforce development. 7 Under President Yoweri Museveni?s leadership, economic development could be jump started by the national...-accessible text data; 2) to understand what the workforce demographics are after 30 years of HIV and AIDS activities from mainly INGOs, FBOs, and CBOs; 3) to determine what change agents (ABC National AIDS program, INGOs, FBOs, CBOs), leaderships (clergy...

Howard, Debra Mayes

2005-02-17T23:59:59.000Z

416

E-Print Network 3.0 - aging glassy systems Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

shear melting and aging experiments... was the first to term this phenomenon as phy- sical aging 26, 29, 30. Aging in glassy materials contin- ues... at that tempera-...

417

Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications  

SciTech Connect (OSTI)

Advanced glycation or glycoxidation end-products (AGE) increase in tissue proteins with age, and their rate of accumulation is increased in diabetes, nephropathy and inflammatory diseases. AGE inhibitors include a range of compounds that are proposed to act by trapping carbonyl and dicarbonyl intermediates in AGE formation. However, some among the newer generation of AGE inhibitors lack reactive functional groups that would trap reaction intermediates, indicating an alternative mechanism of action. We propose that AGE inhibitors function primarily as chelators, inhibiting metal-catalyzed oxidation reactions. The AGE-inhibitory activity of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers is also consistent with their chelating activity. Finally, compounds described as AGE breakers, or their hydrolysis products, also have strong chelating activity, suggesting that these compounds also act through their chelating activity. We conclude that chelation is the common, and perhaps the primary, mechanism of action of AGE inhibitors and breakers, and that chronic, mild chelation therapy should prove useful in treatment of diabetes and age-related diseases characterized by oxidative stress, inflammation and increased chemical modification of tissue proteins by advanced glycoxidation and lipoxidation end-products.

Nagai, Rhoji; Murray, David B.; Metz, Thomas O.; Baynes, John

2012-03-01T23:59:59.000Z

418

Localized or Systemic {italic In Vivo} Heat-Inactivation of Human Immunodeficiency Virus (HIV): A Mathematical Analysis  

SciTech Connect (OSTI)

Temperatures as low as 42 C, maintained for a little as 25 minutes, inactivate {approx}25% of HIV. Furthermore, human immunodeficiency virus (HIV)-infected T-cells are more sensitive to heat than healthy lymphocytes and susceptibility increases when the cells are pre-sensitized by exposure to tumor necrosis factor. Thus, induction of a whole-body hyperthermia, or hyperthermia specifically limited to tissues having a high viral load, are potential antiviral therapies for acquired immunodeficiency disease (AIDS). Accordingly, we incorporated therapeutic hyperthermia into an existing mathematical model which evaluates the interaction between HIV and CD4{sup +} T cells. Given the assumptions and limitations of this model, the results indicate that a daily therapy, reducing the population of actively infected cells by 40% or infectious virus by 50%, would effectively reverse the depletion of T cells. In contrast, a daily reduction of 20% of either actively infected cells or infectious virus would have a marginal effect. However, reduction by 20% of both actively infected cells and infectious virus could restore T cell numbers, assuming that permanent damage had not been inflicted on the thymus. Whole-body hyperthermia seems unlikely to be clinically useful, unless it can be induced non-invasively without general anesthesia. In contrast, heating directed specifically to areas of viral concentration may be effective and have a suitable risk/benefit ratio.

Pennypacker, Carl R.; Perelson, A.S.; Nys, N.; Nelson, G.; Sessler, D.I.

1993-12-15T23:59:59.000Z

419

age tumor size: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

alternate body arches, fin cartilage 422 AGE AND GROWTH OF SKIPJACK TUNA, KATSUWONUS PELAMIS, AND YELLOWFIN TUNA, THUNNUS ALBACARES, AS INDICATED Environmental Sciences and...

420

Influence of Aging and Environment on Nanoparticle Chemistry...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of cerium in cerium oxide nanoparticles is studied in detail. The influence of synthesis medium, aging time and local environment on the oxidation state switching, between +3 and...

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

aged patients usefulness: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

(6-month old, 12-month old, and adult) based on auditory event-related potentials Reilly, James P. 34 USING OBJECTIVE CRITERIA AND MULTIPLE REGRESSION MODELS FOR AGE...

422

accelerated aging studies: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the nominal one, increasing background and pile-up event probability. This requires detector performances which are currently under study in intensive R&D activities. Aging is...

423

age spectrum epidemiology: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of a young supernova. We associate this break with the phenomenon of synchrotron aging of radiating electrons. From the break in the spectrum we calculate the magnetic field...

424

age experimental analysis: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Websites Summary: , by improving the seismic hazard evaluation using probabilistic seismic hazard assessment (PSHA) methodsSeismic vulnerability assessment to slight dam- age...

425

The Work of Art in the Age of Deindustrialization  

E-Print Network [OSTI]

Deindustrialization By Jasper Quentin Bernes A dissertationof Deindustrialization by Jasper Quentin Bernes Doctor ofAge of Deindustrialization Jasper Bernes i Acknowledgments

Bernes, Jasper

2012-01-01T23:59:59.000Z

426

An Accelerated Aging Method for Diesel Exhaust Aftertreatment...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

for Diesel Aftertreatment Devices Impact of Fuel Metal Impurities on Diesel Exhaust Catalysts Rapid Aging Protocols for Diesel Aftertreatment Devices: NOx Abatement Catalysts...

427

Empowering Communities in the Age of E-Government | Department...  

Broader source: Energy.gov (indexed) [DOE]

in the Age of E-Government (March 2006) More Documents & Publications Technology Transfer for Brownfields Redevelopment Project Environmental Justice and Public...

428

Strategy for Aging Tests of Fuel Cell Membranes (Presentation...  

Broader source: Energy.gov (indexed) [DOE]

Aging Tests Advanced Post Mortem Analysis Concluding Remarks Radiation Grafted Fuel Cell Membranes Lorenz Gubler, Paul Scherrer Institut, 2007 HTWG Meeting @ 212th ECS...

429

aged adults: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

The "Aging in Place" project strives to delay taking that first step away from the family home. Through the careful placement of technological support we believe older...

430

age shetland implications: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

initial pricing of this program are not included--see below; all land and water transportation; airport Rowley, Clarence W. 111 Supercomputing Comes of Age Computer Technologies...

431

Aging Impairs Myocardial Fatty Acid and Ketone Oxidation and...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

that aging modifies substrate utilization and alters insulin sensitivity in mouse heart when provided multiple substrates. In vivo cardiac function was measured with...

432

Microsoft Word - CASS_Aging-LWRS_5YR_Plan  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

LTR-2012440 Light Water Reactor Sustainability Cast Stainless Steel Aging Research Plan September 2012 Prepared by: T. S. Byun and J. T. Busby Oak Ridge National Laboratory This...

433

Investigation of Aging Mechanisms in Lean NOx Traps  

Broader source: Energy.gov (indexed) [DOE]

Annual Merit Review 1 Investigation of Aging Mechanisms in Lean NOx Traps Mark Crocker Center for Applied Energy Research, University of Kentucky May 20, 2009 This presentation...

434

aging colloidal glass: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Matter (arXiv) Summary: We use confocal microscopy to directly visualize the dynamics of aging colloidal glasses. We prepare a colloidal suspension at high density, a...

435

Application of RIMS to the Study of Beryllium ChronologyApplication of RIMS to the Study of Beryllium Chronology in Early Solar System Condensatesin Early Solar System Condensates  

E-Print Network [OSTI]

- tion events from the first days of the early solar system. SIMS analyses use large analytical spot of Beryllium Chronology in Early Solar System Condensatesin Early Solar System Condensates K. B. Knight1 of Be decay products shows potential for addressing early solar system events.Resonant Ionization (RIMS

Grossman, Lawrence

436

ENERGY FEEDBACK FROM X-RAY BINARIES IN THE EARLY UNIVERSE  

SciTech Connect (OSTI)

X-ray photons, because of their long mean-free paths, can easily escape the galactic environments where they are produced, and interact at long distances with the intergalactic medium, potentially having a significant contribution to the heating and reionization of the early universe. The two most important sources of X-ray photons in the universe are active galactic nuclei (AGNs) and X-ray binaries (XRBs). In this Letter we use results from detailed, large scale population synthesis simulations to study the energy feedback of XRBs, from the first galaxies (z ? 20) until today. We estimate that X-ray emission from XRBs dominates over AGN at z ?> 6-8. The shape of the spectral energy distribution of the emission from XRBs shows little change with redshift, in contrast to its normalization which evolves by ?4 orders of magnitude, primarily due to the evolution of the cosmic star-formation rate. However, the metallicity and the mean stellar age of a given XRB population affect significantly its X-ray output. Specifically, the X-ray luminosity from high-mass XRBs per unit of star-formation rate varies an order of magnitude going from solar metallicity to less than 10% solar, and the X-ray luminosity from low-mass XRBs per unit of stellar mass peaks at an age of ?300 Myr and then decreases gradually at later times, showing little variation for mean stellar ages ?> 3 Gyr. Finally, we provide analytical and tabulated prescriptions for the energy output of XRBs, that can be directly incorporated in cosmological simulations.

Fragos, T.; Zezas, A. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)] [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Lehmer, B. D. [The Johns Hopkins University, Homewood Campus, Baltimore, MD 21218 (United States)] [The Johns Hopkins University, Homewood Campus, Baltimore, MD 21218 (United States); Naoz, S. [Institute for Theory and Computation, Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)] [Institute for Theory and Computation, Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Basu-Zych, A., E-mail: tfragos@cfa.harvard.edu [NASA Goddard Space Flight Centre, Code 662, Greenbelt, MD 20771 (United States)

2013-10-20T23:59:59.000Z

437

Data Analysis for ARRA Early Fuel Cell Market Demonstrations (Presentation)  

SciTech Connect (OSTI)

Presentation about ARRA Early Fuel Cell Market Demonstrations, including an overview of the ARRE Fuel Cell Project, the National Renewable Energy Laboratory's data analysis objectives, deployment composite data products, and planned analyses.

Kurtz, J.; Wipke, K.; Sprik, S.; Ramsden, T.

2010-05-01T23:59:59.000Z

438

Data Analysis of Early Fuel Cell Market Demonstrations (Presentation)  

SciTech Connect (OSTI)

Presentation about early fuel cell markets, the National Renewable Energy Laboratory's Hydrogen Secure Data Center and its role in data analysis and demonstrations, and composite data products, and results reported to multiple stakeholders.

Kurtz, J.; Ramsden, T.; Wipke, K.; Sprik, S.

2009-11-17T23:59:59.000Z

439

Arnold Schwarzenegger A DESIGN GUIDE FOR EARLY-MARKET  

E-Print Network [OSTI]

Arnold Schwarzenegger Governor A DESIGN GUIDE FOR EARLY-MARKET ELECTROCHROMIC WINDOWS Project Advisory Committee for taking the time to provide insightful technical and market-related input SAGE Electrochromics, Inc. Micheal Myser SAGE Electrochromics, Inc. John Durschinger Skidmore, Owings

440

The early planning and development of Oklahoma City  

E-Print Network [OSTI]

An analysis of the planning, development, and implementation of Oklahoma City's Grand Boulevard. In the early days of 1909, a plan emerged to build an expansive parks and boulevard system to encircle Oklahoma City. Such ...

Humphreys, Blair D. (Blair David)

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Sweden -Holy Roman Empire Early Modern Cultural and Legal  

E-Print Network [OSTI]

Sweden - Holy Roman Empire Early Modern Cultural and Legal Transfer in a wider European Perspective to explore issues related to transfer processes between Sweden and the Holy Ro- man Empire. The topics

Kallenrode, May-Britt

442

aspects early stages: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Ryblewski 2012-07-03 104 A three stage model for the inner engine of Gamma Ray Burst: Prompt emission and early afterglow Astrophysics (arXiv) Summary: We propose a new model...

443

albicans early stage: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Last Page Topic Index 101 A three stage model for the inner engine of Gamma Ray Burst: Prompt emission and early afterglow Astrophysics (arXiv) Summary: We propose a new model...

444

amp inducible early: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

shows the Bode magnitude plots for both VoVi and A (j). The figure shows Leach Jr.,W. Marshall 125 Original article Role of the uterus in early regression of corpora lutea...

445

The Construction of Early Modernity in Spanish Film  

E-Print Network [OSTI]

themselves around some of most representative subjects in early modernity: the Monarchy and Nobility, and the Spanish Inquisition. Studied also is the most expensive Spanish period film, Alatriste (2006). Through the analysis of artistic, industrial...

Zarate Casanova, Miguel Angel

2011-10-21T23:59:59.000Z

446

Structured Regions of Alpha-synuclein Fibrils Include the Early...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

diseases. Three single point mutations in the AS gene, as well as multiplication of the wild-type (WT) AS allele, have been previously identified in families with early-onset PD....

447

LANL, LLNL researchers among Early Career Research Program award...  

National Nuclear Security Administration (NNSA)

Urban Right photo: LLNL's Yuan Ping stands next to the target chamber in the Europa laser bay, part of the Jupiter Laser Facility. LANL, LLNL researchers among Early Career...

448

Early Islamic architecture in Iran (637-1059)  

E-Print Network [OSTI]

This thesis discusses the architecture of early Islamic Iran (16-450/637-1059). To better understand the architectural history of this period, it is necessary to specify in detail how it took shape and to describe its ...

Anisi, Alireza

2008-01-01T23:59:59.000Z

449

Growing Up in Scotland: Pregnancy, Birth and Early Parenting  

E-Print Network [OSTI]

The Growing Up in Scotland study ( GUS) is an important new longitudinal research project aimed at tracking the lives of a cohort of Scottish children from the early years, through childhood and beyond. Its principal aim is to provide information...

Government, Scottish

2007-01-08T23:59:59.000Z

450

Early remodeling of the neocortex upon episodic memory encoding  

E-Print Network [OSTI]

Understanding the mechanisms by which long-term memories are formed and stored in the brain represents a central aim of neuroscience. Prevailing theory suggests that long-term memory encoding involves early plasticity ...

Ericsson, M.

451

8.286 The Early Universe, Spring 2004  

E-Print Network [OSTI]

The Early Universe provides an introduction to modern cosmology. The first half deals with the development of the big-bang theory from 1915 to 1980, and latter half with recent impact of particle theory.

Guth, Alan

452

Early experience improving the provisioning process to enhance scientific collaborations  

E-Print Network [OSTI]

1 Early experience improving the provisioning process to enhance scientific implemented to improve the provisioning process for researchers? We describe an approach for significantly improving the provisioning process based on Software

Tennessee, University of

453

Superstring dominated early universe and epoch dependent gauge coupling  

E-Print Network [OSTI]

We have explored the possibility that the universe at very early stage was dominated by (macroscopic) heterotic strings. We have found that the dimensionless parameter $G\\mu$ for the heterotic strings varies from $10^{-2}$ to $10^{-4}$ as the universe evolve from the matter dominance to radiation dominance. This led to the interesting consequence of epoch dependent gauge coupling constant. The gauge coupling constant at early times was found to be much stronger than the present strong interaction.

A. K. Chaudhuri

1997-06-13T23:59:59.000Z

454

Theoretical foundation for measuring the groundwater age distribution.  

SciTech Connect (OSTI)

In this study, we use PFLOTRAN, a highly scalable, parallel, flow and reactive transport code to simulate the concentrations of 3H, 3He, CFC-11, CFC-12, CFC-113, SF6, 39Ar, 81Kr, 4He and themean groundwater age in heterogeneous fields on grids with an excess of 10 million nodes. We utilize this computational platform to simulate the concentration of multiple tracers in high-resolution, heterogeneous 2-D and 3-D domains, and calculate tracer-derived ages. Tracer-derived ages show systematic biases toward younger ages when the groundwater age distribution contains water older than the maximum tracer age. The deviation of the tracer-derived age distribution from the true groundwater age distribution increases with increasing heterogeneity of the system. However, the effect of heterogeneity is diminished as the mean travel time gets closer the tracer age limit. Age distributions in 3-D domains differ significantly from 2-D domains. 3D simulations show decreased mean age, and less variance in age distribution for identical heterogeneity statistics. High-performance computing allows for investigation of tracer and groundwater age systematics in high-resolution domains, providing a platform for understanding and utilizing environmental tracer and groundwater age information in heterogeneous 3-D systems. Groundwater environmental tracers can provide important constraints for the calibration of groundwater flow models. Direct simulation of environmental tracer concentrations in models has the additional advantage of avoiding assumptions associated with using calculated groundwater age values. This study quantifies model uncertainty reduction resulting from the addition of environmental tracer concentration data. The analysis uses a synthetic heterogeneous aquifer and the calibration of a flow and transport model using the pilot point method. Results indicate a significant reduction in the uncertainty in permeability with the addition of environmental tracer data, relative to the use of hydraulic measurements alone. Anthropogenic tracers and their decay products, such as CFC11, 3H, and 3He, provide significant constraint oninput permeability values in the model. Tracer data for 39Ar provide even more complete information on the heterogeneity of permeability and variability in the flow system than the anthropogenic tracers, leading to greater parameter uncertainty reduction.

Gardner, William Payton; Arnold, Bill Walter

2014-01-01T23:59:59.000Z

455

E-Print Network 3.0 - age structured equations Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

ageing may result in biases in stock assessments and Summary: recapture and known-age data. As with Equation 1, for a given true age b, the bias (b) of the observed age... to...

456

Challenges for Lithuania: Ignalina NPP Early Closure  

SciTech Connect (OSTI)

As a condition of accession into the European Union (EU), Lithuania is committed to the closure and decommissioning of Ignalina NPP comprising two RBMK-1500 reactor units (Fig. 1). It was agreed in a special protocol to the Accession Treaty that, in return for adequate EU financial assistance, Unit 1 would be closed before 2005 and Unit 2 by the end of 2009. The first unit was duly shut down on December 31, 2004. Lithuania, which has borders with Russia (Kaliningrad territory), Poland, Latvia and Belarus, spent fifty years as part of the Soviet Union and was deeply integrated into its economy and electrical infrastructure. At the break-up of the USSR, Lithuania inherited electricity generating capacity designed to supply the north-west region including ownership of Ignalina NPP located in the north-east of the country. Ignalina NPP Unit 1 was commissioned in 1983, Unit 2 in 1987; the planned lifespan of each unit was 30 years. Construction of a third unit was started but never completed. Since Lithuania became independent in 1990, Ignalina NPP has typically contributed more than 70% of national power supply. The town of Visaginas (population approx. 30,000) was purpose built to serve the plant and staff were brought in from throughout the USSR. With 3200 direct employees, Ignalina NPP remains by far the largest employer. Although there are pockets of Russian-language speakers in communities throughout Lithuania, Visaginas is the only example on a whole-town scale. Thus closure of Ignalina NPP within the restricted timescale required by the EU Accession Treaty commitment set an exceptional challenge to Lithuania. However, since the preparatory phase of decommissioning started in 2000, notable progress has been made, experience gained and lessons learnt. At present Unit 1 remains partially fueled in a state of care and maintenance. Partly burnt fuel is being transferred from Unit 1 to Unit 2 for further irradiation in order to minimize the commitment of new fuel thereby reducing operating costs and the final quantity of spent fuel. Design and construction of the facilities for spent fuel storage, waste processing and free-release is ongoing. The siting of the Near Surface Repository is now in the final stages of approval and construction of the landfill facility is under tendering. In order to facilitate the approval process and minimize the transport of waste, both disposal facilities will be within the boundary of the NPP site. Approximately 450 staff are employed at the shutdown Unit 1 for the safe maintenance of essential systems. The total staffing level at the plant is currently being reduced by around 200 each year, with a larger release to take place at the closure of Unit 2. It is envisaged that 2000 staff will be required for the dismantling operations. Although Ignalina NPP is still in the early stages of closure and decommissioning, some important lessons have already been learnt: Firstly, the importance considering social and financial issues as well as technical factors in deciding the decommissioning strategy. This should be done before the preparation is started of the FDP. The same broad consideration should also be given to the economic restructuring of the local area. Consultation is necessary with local and national authorities, and other stakeholders up to ensure a common vision. At Ignalina NPP it was considered essential to staff morale and the maintenance of a strong safety culture to guarantee the special social and employment benefits to dismissed staff in law [9]. At the same time, measures were also adopted to encourage certain key personnel to remain at the plant until closure. The case of Lithuania, which at independence had no legislative framework or management infrastructure for radioactive waste, may be exceptional; however, for all decommissioning projects it is necessary to have, from the outset, a clear strategy on waste storage and disposal. Finally, coordination at all levels must be assured, especially with the involvement of the nuclear regulators and other regulatory authorities, t

Teskeviciene, Birute [Ministry of Economy, Gedimino pr. 38/2, Vilnius, LT-01104 (Lithuania); Harrison, Peter [Central Project Management Agency, S. Konarskio 13, Vilnius, LT-03109 (Lithuania)

2008-01-15T23:59:59.000Z

457

The Cognitive Aging and Neuroimaging (CAN) Lab The Cognitive Aging and Neuroimaging (CAN)Lab investigates the development of both cognitive and neural processes associated  

E-Print Network [OSTI]

The Cognitive Aging and Neuroimaging (CAN) Lab Overview: The Cognitive Aging and Neuroimaging (CAN)Lab investigates the development of both cognitive and neural processes associated with aging -with a focus on ageMRI to elucidate the cognitive and neural processes underlying age-related differences in cognitive control

Bjørnstad, Ottar Nordal

458

Colored figures Franke & Gaser (2012): Longitudinal changes in individual BrainAGE in healthy aging, mild cognitive impairment, and Alzheimer's disease  

E-Print Network [OSTI]

Colored figures Franke & Gaser (2012): Longitudinal changes in individual BrainAGE in healthy aging, mild cognitive impairment, and Alzheimer's disease Figure 1: Depiction of the BrainAGE concept. A: The model of healthy brain aging is trained with the chronological age and preprocessed structural MRI data

Gaser, Christian

459

The effect of chrome adhesion layer on quartz resonator aging.  

SciTech Connect (OSTI)

This SAND report documents a late start LDRD designed to determine the possible aging effects of a quartz resonator gold adhesion layer. Sandia uses quartz resonators for applications. These applications require a very stable frequency source with excellent aging (low drift) characteristics. These parts are manufactured by one of our qualified vendors outside Sandia Laboratories, Statek Corp. Over the years we, Sandia and the vendor, have seen aging variations that have not been completely explained by the typical mechanisms known in the industry. One theory was that the resonator metallization may be contributing to the resonator aging. This LDRD would allow us to test and analyze a group of resonators with known differentiating metallization and via accelerated aging determine if a chrome adhesion layer used to accept the final gold plating may contribute to poor aging. We worked with our main vendor to design and manufacture a set of quartz resonators with a wide range of metallization thickness ratios between the chrome and gold that will allow us determine the cause of this aging and which plating thickness ratios provide the best aging performance while not degrading other key characteristics.

Wessendorf, Kurt O.; Ohlhausen, James Anthony

2011-03-01T23:59:59.000Z

460

Communicating Coastal Risk Analysis in an Age of Climate Change  

E-Print Network [OSTI]

Communicating Coastal Risk Analysis in an Age of Climate Change TR-11-04 Brian Blanton, John Mc in an Age of Climate Change Brian Blanton, John McGee, Oleg Kapeljushnik Renaissance Computing Institute of climate change complicates matters further. An immersive visualization environment integrating data from

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

aging materials: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

aging materials First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Ageing and Rheology in Soft Materials...

462

International Trade in Natural Gas: Golden Age of LNG?  

E-Print Network [OSTI]

International Trade in Natural Gas: Golden Age of LNG? Yichen Du and Sergey Paltsev Report No. 271;1 International Trade in Natural Gas: Golden Age of LNG? Yichen Du* and Sergey Paltsev* Abstract The introduction of liquefied natural gas (LNG) as an option for international trade has created a market for natural gas where

Gabrieli, John

463

Revised isotopic (40 Ar) age for the lamproite volcano of  

E-Print Network [OSTI]

Revised isotopic (40 Ar/39 Ar) age for the lamproite volcano of Cabezos Negros, Fortuna Basin (lamproites) of the Fortuna Basin in southeast Spain. This age is significantly older than earlier reported K. Because the volcanic rocks are intercalated in the stratigraphic sequence of the Fortuna Basin directly

Utrecht, Universiteit

464

THE ROLE OF AGING AND ONCE-THROUGH-COOLED POWER  

E-Print Network [OSTI]

CALIFORNIA ENERGY COMMISSION THE ROLE OF AGING AND ONCE-THROUGH-COOLED POWER PLANTS IN CALIFORNIA Nyberg, Darryl Metz, Connie Leni. 2009. The Role of Aging and Once-Through-Cooled Power Plants .......................................9 The Performance of Once-Through-Cooled Power Plants 2002

465

Microscopic histochemical changes associated with aging in the feline kidney  

E-Print Network [OSTI]

, 13). This activity increased at one year of age to a moderate level and at 3 years to a high level of activity. A slight non-significant increase in activity was apparent from 5. 5 to 7. 5 years of age (Fig. 14). Aldolase N*-* tive l~omo t...

Kaler, Lawrence William

1975-01-01T23:59:59.000Z

466

Preserved lignin structures in Miocene-aged lignite lithotypes, Bulgaria  

E-Print Network [OSTI]

Preserved lignin structures in Miocene-aged lignite lithotypes, Bulgaria M. Stefanova, O. Maman, B, Orleans Cedex 2, France Abstract Contents of preserved lignin structures in Miocene-aged lignite lithotypes were determined. Phenol aldehydes, ketones and acids released from lignin by CuO oxidative

Paris-Sud XI, Université de

467

Aging management guideline for commercial nuclear power plants-pumps  

SciTech Connect (OSTI)

This Aging Management Guideline (AMG) describes recommended methods for effective detection and mitigation of age-related degradation mechanisms in BWR and PWR commercial nuclear power plant pumps important to license renewal. The intent of this AMG is to assist plant maintenance and operations personnel in maximizing the safe, useful life of these components. It also supports the documentation of effective aging management programs required under the License Renewal Rule 10 CFR Part 54. This AMG is presented in a manner that allows personnel responsible for performance analysis and maintenance to compare their plant-specific aging mechanisms (expected or already experienced) and aging management program activities to the more generic results and recommendations presented herein.

Booker, S.; Katz, D.; Daavettila, N.; Lehnert, D. [MDC-Ogden Environmental and Energy Services, Southfield, MI (United States)

1994-03-01T23:59:59.000Z

468

Readings in Common: Assimilation and Interpretive Authority in Early Modern Spain  

E-Print Network [OSTI]

Practice in Early Modern Spain. Minneapolis: University of1993. Harvey, L. P. Muslims in Spain, 1500-1614. Chicago:of Religion in Early Modern Spain. Princeton: Princeton

Kimmel, Seth Ross

2010-01-01T23:59:59.000Z

469

Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease  

SciTech Connect (OSTI)

Highlights: Inhibitors against MDR HIV-1 protease were designed, synthesized and evaluated. Lead peptide (6a) showed potent inhibition (IC{sub 50}: 4.4 nM) of MDR HIV-1 protease. (6a) Showed favorable binding isotherms against NL4-3 and MDR proteases. (6a) Induced perturbations in the {sup 15}N-HSQC spectrum of MDR HIV-1 protease. Molecular modeling suggested that (6a) may induce total flap closure inMDR protease. -- Abstract: Multidrug-resistant (MDR) clinical isolate-769, human immunodeficiency virus type-1 (HIV-1) protease (PDB ID: (1TW7)), was shown to exhibit wide-open flaps and an expanded active site cavity, causing loss of contacts with protease inhibitors. In the current study, the expanded active site cavity of MDR769 HIV-1 protease was screened with a series of peptide-inhibitors that were designed to mimic the natural substrate cleavage site, capsid/p2. Scanning Ala/Phe chemical mutagenesis approach was incorporated into the design of the peptide series to mimic the substrate co-evolution. Among the peptides synthesized and evaluated, a lead peptide (6a) with potent activity (IC{sub 50}: 4.4 nM) was identified against the MDR769 HIV-1 protease. Isothermal titration calorimetry data showed favorable binding profile for 6aagainst both wild type and MDR769 HIV-1 protease variants. Nuclear magnetic resonance spectrum of {sup 15}N-labeled MDR769 HIV-1 protease in complex with 6a showed some major perturbations in chemical shift, supporting the peptide induced conformational changes in protease. Modeling analysis revealed multiple contacts between 6a and MDR769 HIV-1 protease. The lead peptide-inhibitor, 6a, with high potency and good binding profile can be used as the basis for developing potent small molecule inhibitors against MDR variants of HIV.

Yedidi, Ravikiran S. [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States)] [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States); Muhuhi, Joseck M. [Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States)] [Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States); Liu, Zhigang [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States)] [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States); Bencze, Krisztina Z. [Department of Chemistry, Fort Hays State University, Hays, KS 67601 (United States)] [Department of Chemistry, Fort Hays State University, Hays, KS 67601 (United States); Koupparis, Kyriacos [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States) [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States); Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States); OConnor, Carrie E.; Kovari, Iulia A. [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States)] [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States); Spaller, Mark R. [Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States)] [Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States); Kovari, Ladislau C., E-mail: kovari@med.wayne.edu [Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201 (United States)

2013-09-06T23:59:59.000Z

470

The first million years of the Sun: A calculation of formation and early evolution of a solar-mass star  

E-Print Network [OSTI]

We present the first coherent dynamical study of the cloud fragmentation-phase, collapse and early stellar evolution of a solar mass star. We determine young star properties as the consequence of the parent cloud evolution. Mass, luminosity and effective temperature in the first million years of the proto-Sun result from gravitational fragmentation of a molecular cloud region that produces a cluster of prestellar clumps. We calculate the global dynamical behavior of the cloud using isothermal 3D hydrodynamics and follow the evolution of individual protostars in detail using a 1D radiation-fluid-dynamic system of equations that comprises a correct standard solar model solution, as a limiting case. We calculate the pre-main sequence (PMS) evolutionary tracks of a solar mass star in a dense stellar cluster environment and compare it to one that forms in isolation. Up to an age of 950.000 years differences in the accretion history lead to significantly different temperature and luminosity evolution. As accretion fades and the stars approach their final masses the two dynamic PMS tracks converge. After that the contraction of the quasi-hydrostatic stellar interiors dominate the overall stellar properties and proceed in very similar ways. Hence the position of a star in the Hertzsprung-Russell diagram becomes a function of age and mass only. However, our quantitative description of cloud fragmentation, star formation and early stellar evolution predicts substantial corrections to the classical, i.e. hydrostatic and initially fully convective models: At an age of 1 million years the proto-Sun is twice as bright and 500 Kelvin hotter than according to calculations that neglect the star formation process.

G. Wuchterl; R. Klessen

2001-09-04T23:59:59.000Z

471

Jews, Ethnicity and Identity in Early Modern Hamburg  

E-Print Network [OSTI]

the Late Middle Ages (1286-1603) (New York, 1978), 160-61.the English and the Dutch. 18 In 1603 some Hamburg burgherswere expressed in the 1603 synod of German Jews that met in

Bell, Dean P

2007-01-01T23:59:59.000Z

472

Combined modality therapy for HIV-infected patients with squamous cell carcinoma of the anus: Outcomes and toxicities  

SciTech Connect (OSTI)

Purpose: We report toxicity and survival data of human immunodeficiency virus (HIV)-infected men with anal carcinoma treated with combined modality therapy (CMT) of radiotherapy and concurrent chemotherapy. Methods and Materials: A retrospective review was performed on the records of 17 HIV-positive patients with anal squamous cell carcinoma treated with CMT at our institution between 1991 and 2004. Radiotherapy consisted of 30.6 to 45 Gy to the pelvis, total dose of 50.4 to 59.4 Gy to initial gross disease, at 1.8 Gy/fraction. Chemotherapy consisted of 5-fluorouracil and either mitomycin C or cisplatin. The mean follow-up was 25.6 months (median, 15.6 months; range, 4.6-106 months). Results: Significant acute skin and hematologic toxicity developed in 8 of 17 and 9 of 17 patients, respectively. One patient died 12 days after treatment of progressive disease and sepsis. Significant late toxic sequelae developed in 3 patients: 1 anorectal ulcer, 2 dermatologic (perianal ulceration, hemorrhagic perineal sores and suspected fissure). Fourteen of 15 patients with Stage I-III disease had a complete response; 2 complete responders subsequently had a relapse in the anorectum. For all patients, actuarial 18-month survival was 67%. For patients with Stage I-III disease, survival at last follow-up by low CD4 count (<200) vs. high count (>200) was 4 of 7 vs. 7 of 8, respectively; significant acute toxicities developed in 4 of 8 vs. 6 of 9, respectively. Conclusion: For HIV patients with anal carcinoma, CMT yields reasonable local control with significant acute complications. Survival is lower than in the general population, attributable more to the underlying infection than to the malignancy.

Edelman, Scott [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States)]. E-mail: scotte@radonc.emory.org; Johnstone, Peter [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States)

2006-09-01T23:59:59.000Z

473

Early Oak Ridge Trailer Homes | Y-12 National Security Complex  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation Proposed NewcatalystNeutronEnvironmentZIRKLE FRUIT reducesEarly Career: Emergent... Early Oak

474

Users, technology and space in libraries in the digital age  

E-Print Network [OSTI]

This thesis is a user research study of emerging issues in the use of libraries as public spaces and as information repositories in the digital age. Till recently strong physicality was attached to the library with the ...

G-Chandorkar, Tripti (Gore-Chandorkar)

2005-01-01T23:59:59.000Z

475

Aging effects on oil-contaminated Kuwaiti sand  

SciTech Connect (OSTI)

Large quantities of oil-contaminated sands resulted from the destruction of oil wells and the formation of oil lakes in Kuwait at the end of the Gulf Wa/r. A laboratory testing program was carried out to determine the geotechnical properties of this material and the effect of aging on their properties. Tests included direct shear, triaxial, and consolidation tests on clean and contaminated sand at the same relative density. The influence of aging was examined by testing uncontaminated sand after aging for one, three, and six months in natural environmental conditions. The results indicated increased strength and stiffness due to aging and a reduction of the oil content due to evaporation of volatile compounds. The factors that influence the depth of oil penetration in compacted sand columns were also examined including the type of oil, relative density, and the amount of fines.

Al-Sanad, H.A.; Ismael, N.F. [Kuwait Univ., Safat (Kuwait). Dept. of Civil Engineering

1997-03-01T23:59:59.000Z

476

Enzyme Structure Provides Insights into Cancer and Aging  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Enzyme Structure Provides Insights into Cancer and Aging Print XPD helicase is an enzyme that unwinds the DNA double helix; it is one component of an essential repair mechanism...

477

administration normative aging: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

U.S:pr.aoa.dhhs.govaoastatsaging21demography.html . Administration on Aging. 1999. Profile of Older Americans: 1999. U.S. Department:pr.aoa.dhhs.govaoastatsprofile...

478

Health, Ageing and Ethnicity: A Retrospective and Prospects  

E-Print Network [OSTI]

Health, Ageing and Ethnicity: A Retrospective and Prospects Naina Patel, PhD. Dr. Patel called Minority Elderly Care (MEC) under the EC 5th Framework Research Programme. Formerly the UK

479

Figure 2. Stratigraphic Summary of Ages, Names and Rock Types...  

Gasoline and Diesel Fuel Update (EIA)

2. Stratigraphic Summary of Ages, Names and Rock Types in the ANWR 1002 and Coastal Plain Area of the Alaska North Slope. Potentially Productive Reservoirs and Plays Assessed by...

480

Cognitive training in schizophrenia: golden age or wild west?  

E-Print Network [OSTI]

Golden Age or Wild West? Sophia Vinogradov, Melissa Fisher,Address correspondence to Sophia Vinogradov, M.D. , 116AFrancisco, CA 94121; E-mail: sophia. vinogradov@ucsf.edu.

Vinogradov, Sophia

2013-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "hiv early aging" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

age infant sex: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

old, 12-month old, and adult) based on auditory event-related potentials Reilly, James P. 13 RESEARCH ARTICLE Open Access Sex-related differences and age of peak Physics...

482

advancing age potential: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

old, 12-month old, and adult) based on auditory event-related potentials Reilly, James P. 10 Paradoxical down?regulation of p16 INK4a mRNA with advancing age in Acute...

483

aging decreases expression: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

interacting sensory stimuli... Duncan, Nikki 2013-03-13 35 Analysis of Telomere Length in the Aged mdx Diaphragm with and without Transgenic IGF-I Expression CiteSeer...

484

The Effects of Ageing on Memory and Thinking  

E-Print Network [OSTI]

The main aim of the present study is to examine the effects of ageing on memory and thinking by examining verbal fluency performance. More specifically looking at the differences between older and younger people, to ...

Ford, Amanda

2007-01-01T23:59:59.000Z

485

Determining Remaining Useful Life of Aging Cables in Nuclear...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3624 Determining Remaining Useful Life of Aging Cables in Nuclear Power Plants - Interim Status for FY2014 Milestone Report M3LW-140R04022 September 2014 KL Simmons AM Jones LS...

486

ageing electronic systems: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

a time, due to changes in the load current and due to ageing. The calorimeter light emitting diode (LED) monitoring system has been developed to monitor the PMT gain over time...

487

r Journalof Geology LATE ARCHEAN ZIRCON AGES 419  

E-Print Network [OSTI]

sows t at t e popu a Ion 0 zIrcons in the banded granulite Ch Zr I, which record ages 238UfO6Pb at 2622

Mojzsis, Stephen J.

488

Space-Age Ceramics Get Their Toughest Test  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

operational temperatures projected for hypersonic jet and next-generation gas-turbine engines, but real-time analysis of the mechanical properties of these space-age materials at...

489

System to estimate ages and redshifts for radio galaxies  

E-Print Network [OSTI]

The system allowing a user to operate with simulated curves of spectral energy distribution (SED) and to estimate ages and redshifts by photometric data at server {\\bf sed.sao.ru} is described.

O. V. Verkhodanov; A. I. Kopylov; N. V. Verkhodanova; O. P. Zhelenkova; V. N. Chernenkov; Yu. N. Parijskij; N. S. Soboleva; A. V. Temirova

2001-12-06T23:59:59.000Z

490

Solar System impact rates measured from lunar spherule ages  

E-Print Network [OSTI]

. The samples were irradiated with fast neutrons for 100 hours at the Oregon State University Reactor. Each measured using a MAP 215-C noble gas mass spectrometer. Spherule ages were determined using the 40 Ar/39 Ar

Muller, Richard A.

491

ageing seed pools: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of the methods, expense, and logistics of sample collection. The ability to inventory wild populations would be greatly expanded if pooled adult age-class data (e.g.,...

492

arabian iron age: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

iron deficiency should be the goal of nutritional intervention programs. In the United States, approximately 5 % of children from 1-5 years of age suffer from iron deficiency...

493

ageing study bhas: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Growing-Stock Study at Age 401 William W. Oliver2 Abstract in the southwestern United States (Oliver and Ryker 1990). Throughout this vast area ponderosa pine is one of the most...

494

aging study bhas: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Growing-Stock Study at Age 401 William W. Oliver2 Abstract in the southwestern United States (Oliver and Ryker 1990). Throughout this vast area ponderosa pine is one of the most...

495

Renal Tumors: Technical Success and Early Clinical Experience with Radiofrequency Ablation of 18 Tumors  

SciTech Connect (OSTI)

Purpose. To evaluate the feasibility, safety, and technical efficacy of image-guided radiofrequency ablation (RFA) for the treatment of small peripheral renal tumors and to report our early results with this treatment modality. Methods. Twenty-two RFA sessions for 18 tumors were performed in 11 patients with renal tumors. Indications included coexistent morbidity, high surgical or anesthetic risk, solitary kidney, and hereditary predisposition to renal cell carcinoma. Ten patients had CT-guided percutaneous RFA performed on an outpatient basis. One patient had open intraoperative ultrasound-guided RFA. Technical success was defined as elimination of areas that enhanced at imaging within the entire tumor. With the exception of one patient with renal insufficiency who required gadolinium-enhanced MRI, the remaining patients underwent contrast-enhanced CT for post-treatment follow-up assessment. Follow-up was performed after 2-4 weeks and then at 3, 6, 12 months, and every 12 months thereafter. Results. Fourteen (78%) of 18 tumors were successfully ablated with one session. Three of the remaining four tumors required two sessions for successful ablation. One tumor will require a third session for areas of persistent enhancement. Mean patient age was 72.82 {+-} 10.43 years. Mean tumor size was 1.95 {+-} 0.79 cm. Mean follow-up time was 10.91 months. All procedures were performed without any major complications. Conclusions. Our early experience with percutaneous image-guided radiofrequency ablation demonstrates it to be a feasible, safe, noninvasive, and effective treatment of small peripheral renal tumors.

Sabharwal, Rohan, E-mail: rohan50000@yahoo.com; Vladica, Philip [Westmead Hospital, Department of Radiology (Australia)

2006-04-15T23:59:59.000Z

496

Helena Petrovna Blavatsky: missionary to the gilded age  

E-Print Network [OSTI]

HELENA PETROVNA BLAVATSKY: MISSIONARY TO THE GILDED AGE A Thesis by MARJORIE JO NEELY Submitted to the Graduate College of Texas AiM Vniversity in partial fulfillment of the requirement for the degree of MASTER OF ARTS August 1977 Major... Subject: History HELENA PETROVNA BLAVATSKY: MISSIONARY TO THE GILDED AGE A Thesis MARJORIE JO NEELY Approved as to style and content by: Cha rman o Commit ee H o epar en Mem er m er August 1977 ABSTRACT Helena Petrovna Blavatsky: Missionary...

Neely, Marjorie Jo

1977-01-01T23:59:59.000Z

497

Evidence of aging effects on certain safety-related components  

SciTech Connect (OSTI)

In response to interest shown by the Nuclear Energy Agency (NEA), Principal Working Group I (PWG- 1) of the Committee on the Safety of Nuclear Installations (CSNI) conducted a generic study on the effects of aging of active components in nuclear power plants. (This focus on active components is consistent with PWG-l`s mandate; passive components are primarily within the mandate of PWG-3.) Representatives from France, Sweden, Finland, Japan, the United States, and the United Kingdom participated in the study by submitting reports documenting aging studies performed in their countries. This report consists of summaries of those reports, along with a comparison of the various statistical analysis methods used in the studies. The studies indicate that with some exceptions, active components generally do not present a significant aging problem in nuclear power plants. Design criteria and effective preventative maintenance programs, including timely replacement of components, are effective in mitigating potential aging problems. However, aging studies (such as qualitative and statistical analyses of failure modes and maintenance data) are an important part of efforts to identify and solve potential aging problems. Solving these problems typically includes such strategies as replacing suspect components with improved components, and implementing improved maintenance programs.

Magleby, H.L.; Atwood, C.L.; MacDonald, P.E.; Edson, J.L.; Bramwell, D.L. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)

1996-01-01T23:59:59.000Z

498

Aging study of boiling water reactor high pressure injection systems  

SciTech Connect (OSTI)

The purpose of high pressure injection systems is to maintain an adequate coolant level in reactor pressure vessels, so that the fuel cladding temperature does not exceed 1,200{degrees}C (2,200{degrees}F), and to permit plant shutdown during a variety of design basis loss-of-coolant accidents. This report presents the results of a study on aging performed for high pressure injection systems of boiling water reactor plants in the United States. The purpose of the study was to identify and evaluate the effects of aging and the effectiveness of testing and maintenance in detecting and mitigating aging degradation. Guidelines from the United States Nuclear Regulatory Commission`s Nuclear Plant Aging Research Program were used in performing the aging study. Review and analysis of the failures reported in databases such as Nuclear Power Experience, Licensee Event Reports, and the Nuclear Plant Reliability Data System, along with plant-specific maintenance records databases, are included in this report to provide the information required to identify aging stressors, failure modes, and failure causes. Several probabilistic risk assessments were reviewed to identify risk-significant components in high pressure injection systems. Testing, maintenance, specific safety issues, and codes and standards are also discussed.

Conley, D.A.; Edson, J.L.; Fineman, C.F. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)

1995-03-01T23:59:59.000Z

499

Age determination of the HR8799 planetary system using asteroseismology  

E-Print Network [OSTI]

Discovery of the first planetary system by direct imaging around HR8799 has made the age determination of the host star a very important task. This determination is the key to derive accurate masses of the planets and to study the dynamical stability of the system. The age of this star has been estimated using different procedures. In this work we show that some of these procedures have problems and large uncertainties, and the real age of this star is still unknown, needing more observational constraints. Therefore, we have developed a comprehensive modeling of HR8799, and taking advantage of its gamma Doradus-type pulsations, we have estimated the age of the star using asteroseismology. The accuracy in the age determination depends on the rotation velocity of the star, and therefore an accurate value of the inclination angle is required to solve the problem. Nevertheless, we find that the age estimate for this star previously published in the literature ([30,160] Myr) is unlikely, and a more accurate value ...

Moya, A; Barrado, D; Hernndez, A Garca; Aberasturi, M; Montesinos, B; Aceituno, F

2010-01-01T23:59:59.000Z

500

Near-Infrared Observations of Globular Clusters in NGC 4472, NGC 4594, NGC 3585 and NGC 5813 and Implications for their Ages and Metallicities  

E-Print Network [OSTI]

We present near-infrared photometry of the globular cluster systems of the early-type galaxies NGC 4472, NGC 4594, NGC 3585, and NGC 5813. We combine these near-infrared data, obtained with PANIC at the Magellan Baade 6.5m telescope, with archival optical HST and FORS/VLT data, and use the optical to near-infrared colors to constrain the ages and metallicities of the globular clusters around the target galaxies. For NGC 4472 we have the most extensive near-infrared and optical photometric dataset. These colors show that the NGC 4472 globular cluster system has a broad metallicity distribution and that the clusters are predominantly old (i.e. ages of about 10 Gyr or more). This result agrees well with earlier spectroscopic work on NGC 4472, and is evidence that the combination of optical to near-infrared colors can identify predominantly old systems and distinguish these from systems with a substantial intermediate age component. Based on the smaller sample of combined optical and near-infrared data NGC 4594 and NGC 3585 appear to have predominantly old globular cluster systems, while that of NGC 5813 may have a more significant age spread. We also match our sample of globular clusters with near-infrared and optical photometry to Chandra X-ray source detections in these galaxies, and discuss how the probability that a globular cluster hosts a low-mass X-ray binary depends on metallicity and age.

Maren Hempel; Steve Zepf; Arunav Kundu; Doug Geisler; Thomas J. Maccarone

2007-02-19T23:59:59.000Z