Powered by Deep Web Technologies
Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

High-Throughput Screening Techniques  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Throughput Throughput Screening Techniques for Biomass Conversion Stephen R. Decker & Roman Brunecky & Melvin P. Tucker & Michael E. Himmel & Michael J. Selig Published online: 14 October 2009 # US Government 2009 Abstract High-throughput (HTP) screening of biomass or biomass-degrading enzymes, regardless of the desired outcome, is fraught with obstacles and challenges not typically faced in more traditional biotechnology. The enzyme systems are complex and synergistic and the substrate is highly heterogeneous, insoluble, and difficult to dispense. Digestions are often carried out for days at temperatures of 50°C or higher, leading to significant challenges regarding evaporation control in small well volumes. Furthermore, it is often desirable to condition or "pretreat" the biomass at extreme temperatures and/or pH to enhance enzyme digestibility.

2

High-Throughput Pretreatment and Hydrolysis Systems for Screening Biomass Species in Aqueous Pretreatment of Plant Biomass  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

High-throughput High-throughput Pretreatment and Hydrolysis Systems for Screening Biomass Species in Aqueous Pretreatment of Plant Biomass Jaclyn D. DeMartini 1,2,3,Ã and Charles E. Wyman 1,2,3 1 Department of Chemical and Environmental Engineering, University of California, Riverside, USA 2 Center for Environmental Research and Technology, University of California, Riverside, USA 3 BioEnergy Science Center, Oak Ridge, USA 22.1 Introduction: The Need for High-throughput Technologies The primary barrier to low-cost biological conversion of lignocellulosic biomass to renewable fuels and chemicals is plant recalcitrance, that is to say, resistance of cell walls to deconstruction by enzymes or microbes [1,2]. However, the discovery and use of biomass species with reduced recalcitrance, when com- bined with optimized pretreatment processes and enzyme mixtures, could potentially

3

High-Throughput and Combinatorial Screening of Hydrogen Storage...  

Broader source: Energy.gov (indexed) [DOE]

High-Throughput and Combinatorial Screening of Hydrogen Storage Materials (presentation) High-Throughput and Combinatorial Screening of Hydrogen Storage Materials (presentation)...

4

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Broader source: Energy.gov (indexed) [DOE]

UOP LLC. All rights reserved. High ThroughputCombinatorial Screening of Hydrogen Storage Materials: UOP Approaches High ThroughputCombinatorial Screening of Hydrogen Storage...

5

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Broader source: Energy.gov (indexed) [DOE]

High ThroughputCombinatorial Screening of Hydrogen Storage Materials (presentation) High ThroughputCombinatorial Screening of Hydrogen Storage Materials (presentation) Presented...

6

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Broader source: Energy.gov (indexed) [DOE]

ThroughputCombinatorial Screening of Hydrogen Storage Materials: UOP Approaches High ThroughputCombinatorial Screening of Hydrogen Storage Materials: UOP Approaches Presentation...

7

Engineering of a high-throughput screening system to identify cellulosic biomass, pretreatments, and enzyme formulations that enhance sugar release  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Engineering Engineering of a High-Throughput Screening System to Identify Cellulosic Biomass, Pretreatments, and Enzyme Formulations That Enhance Sugar Release Michael H. Studer, Jaclyn D. DeMartini, Simone Brethauer, Heather L. McKenzie, Charles E. Wyman Chemical and Environmental Engineering Department, Center for Environmental Research and Technology, Bourns College of Engineering, University of California Riverside, 1084 Columbia Avenue, Riverside, California 92507; telephone: þ951-781-5791; fax: þ951-781-5790; e-mail: charles.wyman@ucr.edu Received 7 April 2009; revision received 21 August 2009; accepted 31 August 2009 Published online 3 September 2009 in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/bit.22527 ABSTRACT: The recalcitrance of cellulosic biomass, the only abundant, sustainable feedstock for making liquid fuels, is a primary

8

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

Broader source: Energy.gov (indexed) [DOE]

Workshop HIGH THROUGHPUTCOMBINATORIAL SCREENING OF HYDROGEN STORAGE MATERIALS June 26, 2007 Tom Boussie Symyx Technologies Symyx develops and applies proprietary high-throughput...

9

Microfluidic Technologies for High-Throughput Screening Applications  

E-Print Network [OSTI]

Microfluidic Technologies for High-Throughput Screening Applications Thesis by Todd Thorsen, patiently giving me advice on a large variety of subjects, ranging from microfluidics to optics of microfluidic devices for high-throughput screening applications, such as mutant enzyme libraries expressed

Quake, Stephen R.

10

Development and optimization of high-throughput zebrafish screening platform  

E-Print Network [OSTI]

The high-throughput zebrafish screening platform is a revolutionary tool that enables subcellular precision in vivo whole animal screening of Danio Rerio. It can perform laser surgery and/or imaging in less than twenty ...

Koo, Bryan Kyo

2010-01-01T23:59:59.000Z

11

High-throughput vertebrate total analysis/screening platform  

E-Print Network [OSTI]

High-throughput screening (HTS) is seen as one of the most promising technologies to facilitate biomedical studies and pharmaceutical discoveries. Although large varieties of in vitro HTS technologies have opened great ...

Chang, Tsung-Yao, Ph. D. Massachusetts Institute of Technology

2012-01-01T23:59:59.000Z

12

High throughput chemical munitions treatment system  

SciTech Connect (OSTI)

A new High-Throughput Explosive Destruction System is disclosed. The new system is comprised of two side-by-side detonation containment vessels each comprising first and second halves that feed into a single agent treatment vessel. Both detonation containment vessels further comprise a surrounding ventilation facility. Moreover, the detonation containment vessels are designed to separate into two half-shells, wherein one shell can be moved axially away from the fixed, second half for ease of access and loading. The vessels are closed by means of a surrounding, clam-shell type locking seal mechanisms.

Haroldsen, Brent L. (Manteca, CA); Stofleth, Jerome H. (Albuquerque, NM); Didlake, Jr., John E. (Livermore, CA); Wu, Benjamin C-P (San Ramon, CA)

2011-11-01T23:59:59.000Z

13

High-Throughput Thin Film Approach for Screening of Temperature-Pressure-Composition Phase Space  

SciTech Connect (OSTI)

Many solar energy technologies, for example CIGS and CdTe photovoltaics, utilize materials in thin film form. The equilibrium phase diagrams for these and other more novel solar energy materials are not known or are irrelevant because of the non-equilibrium character of the thin film growth processes. We demonstrate a high-throughput thin film approach for screening of temperature-pressure-composition phase diagrams and phase spaces. The examples in focus are novel solar absorbers Cu-N, Cu-O and p-type transparent conductors in the Cr2O3-MnO system. The composition axis of the Cr2O3-MnO phase diagram was screened using a composition spread method. The temperature axis of the Mn-O phase diagram was screened using a temperature spread method. The pressure axes of the Cu-N and Cu-O phase diagrams were screened using rate spread method with the aid of non-equilibrium growth phenomena. Overall these three methods constitute an approach to high-throughput screening of inorganic thin film phase diagrams. This research is supported by U.S. Department of Energy as a part of two NextGen Sunshot projects and an Energy Frontier Research Center.

Zakutayev, A.; Subramaniyan, A.; Caskey, C. M.; Ndione, P. F.; Richards, R. M.; O'Hayre, R.; Ginley, D. S.

2013-01-01T23:59:59.000Z

14

Methods and technologies for high-throughput and high-content small animal screening  

E-Print Network [OSTI]

High-throughput and high-content screening (HTS and HCS) of whole animals requires their immobilization for high-resolution imaging and manipulation. Here we present methods to enable HTS and HCS of the nematode Caenorhabditis ...

Rohde, Christopher, 1979-

2012-01-01T23:59:59.000Z

15

Agenda from the U.S. Department of Energy's High Throughput Screening...  

Broader source: Energy.gov (indexed) [DOE]

Agenda from the U.S. Department of Energy's High Throughput Screening of Hydrogen Storage Materials Workshop on June 26, 2007 Agenda from the U.S. Department of Energy's High...

16

High throughput solar cell ablation system  

DOE Patents [OSTI]

A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.

Harley, Gabriel; Pass, Thomas; Cousins, Peter John; Viatella, John

2012-09-11T23:59:59.000Z

17

High throughput solar cell ablation system  

DOE Patents [OSTI]

A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.

Harley, Gabriel; Pass, Thomas; Cousins, Peter John; Viatella, John

2014-10-14T23:59:59.000Z

18

High Throughput Combinatorial Screening of Biometic Metal-Organic...  

Broader source: Energy.gov (indexed) [DOE]

Throughput Combinatorial Screening of Biometic Metal-Organic Materials for Military Hydrogen-Storage Materials (New Joint Miami UNREL DoDDLA Project) (presentation) High...

19

Laser-Induced Fluorescence Detection in High-Throughput Screening of Heterogeneous Catalysts and Single Cells Analysis  

SciTech Connect (OSTI)

Laser-induced fluorescence detection is one of the most sensitive detection techniques and it has found enormous applications in various areas. The purpose of this research was to develop detection approaches based on laser-induced fluorescence detection in two different areas, heterogeneous catalysts screening and single cell study. First, we introduced laser-induced imaging (LIFI) as a high-throughput screening technique for heterogeneous catalysts to explore the use of this high-throughput screening technique in discovery and study of various heterogeneous catalyst systems. This scheme is based on the fact that the creation or the destruction of chemical bonds alters the fluorescence properties of suitably designed molecules. By irradiating the region immediately above the catalytic surface with a laser, the fluorescence intensity of a selected product or reactant can be imaged by a charge-coupled device (CCD) camera to follow the catalytic activity as a function of time and space. By screening the catalytic activity of vanadium pentoxide catalysts in oxidation of naphthalene, we demonstrated LIFI has good detection performance and the spatial and temporal resolution needed for high-throughput screening of heterogeneous catalysts. The sample packing density can reach up to 250 x 250 subunits/cm{sub 2} for 40-{micro}m wells. This experimental set-up also can screen solid catalysts via near infrared thermography detection.

Hui Su

2001-05-01T23:59:59.000Z

20

Directed Enzyme Evolution and High-Throughput Screening  

E-Print Network [OSTI]

into a commercial process relies on the availability of those with high activity and stability under process optimization process, whereby the fittest variants are selected from an ensemble of mutants [3]. Directed for process scientists today. Choosing the appropriate methods of library generation and screening

Zhao, Huimin

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

High-Throughput Screening Technique for Biomass Conversion in Hot Compressed Water  

Science Journals Connector (OSTI)

High-Throughput Screening Technique for Biomass Conversion in Hot Compressed Water ... Formic acid is known to be converted completely to gaseous products, mainly CO2 and H2 at high temperatures. ... The Ru/TiO2 catalyst is able to convert WSIS (char) to gas, while leaving the oil product practically unaltered with respect to compn. ...

Pavlina Nanou; Wim P. M. van Swaaij; Sascha R. A. Kersten; Guus van Rossum

2012-01-17T23:59:59.000Z

22

Laser-Induced Fluorescence Detection in High-Throughput Screening of Heterogeneous Catalysts and Single Cells Analysis  

SciTech Connect (OSTI)

Laser-induced fluorescence detection is one of the most sensitive detection techniques and it has found enormous applications in various areas. The purpose of this research was to develop detection approaches based on laser-induced fluorescence detection in two different areas, heterogeneous catalysts screening and single cell study. First, the author introduced laser-induced imaging (LIFI) as a high-throughput screening technique for heterogeneous catalysts to explore the use of this high-throughput screening technique in discovery and study of various heterogeneous catalyst systems. This scheme is based on the fact that the creation or the destruction of chemical bonds alters the fluorescence properties of suitably designed molecules. By irradiating the region immediately above the catalytic surface with a laser, the fluorescence intensity of a selected product or reactant can be imaged by a charge-coupled device (CCD) camera to follow the catalytic activity as a function of time and space. By screening the catalytic activity of vanadium pentoxide catalysts in oxidation of naphthalene, they demonstrated LIFI has good detection performance and the spatial and temporal resolution needed for high-throughput screening of heterogeneous catalysts. The sample packing density can reach up to 250 x 250 subunits/cm{sup 2} for 40-{micro}m wells. This experimental set-up also can screen solid catalysts via near infrared thermography detection. In the second part of this dissertation, the author used laser-induced native fluorescence coupled with capillary electrophoresis (LINF-CE) and microscope imaging to study the single cell degranulation. On the basis of good temporal correlation with events observed through an optical microscope, they have identified individual peaks in the fluorescence electropherograms as serotonin released from the granular core on contact with the surrounding fluid.

Hui Su

2001-05-25T23:59:59.000Z

23

Development of Quantitative FRET Technology for SENP Enzyme Kinetics Determinations and High-Sensitive High-Throughput Screening Assay for Protease Inhibitor Discovery  

E-Print Network [OSTI]

chemical inhibitors as a high-throughput screening platform.platform, in which the disruption of SENP towards pre-SUMOs maturation by small chemical

Liu, Yan

2012-01-01T23:59:59.000Z

24

Discovery and High-Throughput Screening of Heteroleptic Iridium Complexes for Photoinduced Hydrogen Production  

E-Print Network [OSTI]

high-throughput photophysical techniques, to identify six potential photosensitizers for use researchers. Simple solar devices focus or collect sunlight, harnessing radiation in order to heat dwellings or drive turbines. Photovoltaic cells can convert solar radiation directly to electrical current

Bernhard, Stefan

25

Reading Dynamic Kinase Activity in Living Cells for High-Throughput Screening  

Science Journals Connector (OSTI)

Here, we describe a general method for high-throughput reading of dynamic kinase activities using ratiometric fluorescent sensors, and showcase an example of reading intracellular activities of protein kinase A (PKA) and the cyclic adenosine monophosphate (cAMP)/PKA pathway downstream of many G-protein coupled receptors (GPCRs). ... Kinases are crucial nodes in the signaling network and emerging drug targets of the 21st century (1). ...

Michael D. Allen; Lisa M. DiPilato; Meghdad Rahdar; Yunzhao R. Ren; Curtis Chong; Jun O. Liu; Jin Zhang

2006-07-21T23:59:59.000Z

26

Constant pressure high throughput membrane permeation testing system  

DOE Patents [OSTI]

The disclosure relates to a membrane testing system for individual evaluation of a plurality of planar membranes subjected to a feed gas on one side and a sweep gas on a second side. The membrane testing system provides a pressurized flow of a feed and sweep gas to each membrane testing cell in a plurality of membrane testing cells while a stream of retentate gas from each membrane testing cell is ported by a retentate multiport valve for sampling or venting, and a stream of permeate gas from each membrane testing cell is ported by a permeate multiport valve for sampling or venting. Back pressure regulators and mass flow controllers act to maintain substantially equivalent gas pressures and flow rates on each side of the planar membrane throughout a sampling cycle. A digital controller may be utilized to position the retentate and permeate multiport valves cyclically, allowing for gas sampling of different membrane cells over an extended period of time.

Albenze, Erik J.; Hopkinson, David P.; Luebke, David R.

2014-09-02T23:59:59.000Z

27

Automation of High?Throughput Crystal Screening and Data Collection at SSRL  

Science Journals Connector (OSTI)

A robotic system for auto?mounting crystals from liquid nitrogen is now operational on SSRL beamlines (Cohen et al. J. Appl. Cryst. (2002). 35 720726). The system uses a small industrial 4?axis robot with a custom built actuator. Once mounted automated alignment of the sample loop to the X?ray beam readies the crystal for data collection. After data collection samples are returned to the cassette. The beamline Dewar accommodates three compact sample cassettes (holding up to 96 samples each). During the past 4 months the system on beamline 11?1 has been used to screen over 1000 crystals. The system has reduced both screening time and manpower. Integration of the hardware components is accomplished in the Distributed Control System architecture developed at SSRL (McPhillips et al. J. Synchrotron Rad. (2002) 9 401406). A crystal?screening interface has been implemented in Blu?Ice. Sample details can be uploaded from an Excel spreadsheet. The JCSG generates these spreadsheets automatically from their tracking database using standard database tools (http://www.jcsg.org). New diffraction image analysis tools are being employed to aid in extracting results. Automation also permits tele?presence. For example samples have been changed during the night without leaving home and scientists have screened crystals 1600 miles from the beamline. The system developed on beamline 11?1 has been replicated onto 1?5 9?1 9?2 and 11?3 and is used by both general users and the JCSG.

Mitchell D. Miller; Linda S. Brinen; Aina Cohen; Ashley M. Deacon; Paul Ellis; Scott E. McPhillips; Timothy M. McPhillips; R. Paul Phizackerley; S. Michael Soltis; Henry van den Bedem; Gnter Wolf; Qingping Xu; Zepu Zhang

2004-01-01T23:59:59.000Z

28

High Throughput Screening of Biologically Functional Small Molecules for Modulating the Expression of FGFR1OP2/wit3.0 in Fibroblasts  

E-Print Network [OSTI]

chemical in our final high throughput assay platform.platform. High Throughput Assay Optimization Most chemicals

Cheng, William J.

2012-01-01T23:59:59.000Z

29

Droplet-based microfluidics for high-throughput screening of a metagenomic library for isolation of microbial enzymes  

Science Journals Connector (OSTI)

Abstract This paper proposes a high-throughput, function-based screening approach of a metagenomic library for isolating novel microbial enzymes by droplet-based microfluidics. We used gel microdroplets (GMDs) dispersed in oil as picoliter-volume reaction vessels for lipolytic enzyme by encapsulating cells in individual GMDs. Using this approach, we monitored the growth of individual cells encapsulated in \\{GMDs\\} and assessed the enzyme reaction activities at the level of an individual GMD. We then applied this method to screen lipolytic enzyme genes from the metagenomic library constructed from soil collected from a quercus serrate forest of Mount Tsukuba, Ibaraki, Japan. In the workflow presented in this study, metagenomic library clones were encapsulated in 100-pL \\{GMDs\\} with a fluorogenic reporter substrate. A total of 67,000 metagenomic library clones can be screened in only 24h with reduced consumption of reagents (i.e., microfluidic \\{GMDs\\} as an efficient tool for metagenomic library screening of industrially relevant enzymes with the potential of significantly reducing the cost and time factors involved in successful practical application of microbial enzymes.

Masahito Hosokawa; Yuri Hoshino; Yohei Nishikawa; Tomotada Hirose; Dong Hyun Yoon; Tetsushi Mori; Tetsushi Sekiguchi; Shuichi Shoji; Haruko Takeyama

2014-01-01T23:59:59.000Z

30

Getter sputtering system for high-throughput fabrication of composition spreads  

SciTech Connect (OSTI)

We describe a sputtering system that can deposit composition spreads in an effectively UHV environment but which does not require the high-throughput paradigm to be compromised by a long pump down each time a target is changed. The system deploys four magnetron sputter guns in a cryoshroud (getter sputtering) which allows elements such as Ti and Zr to be deposited with minimal contamination by oxygen or other reactive background gases. The system also relies on custom substrate heaters to give rapid heating and cool down. The effectiveness of the gettering technique is evaluated, and example results obtained for catalytic activity of a pseudoternary composition spread are presented.

Gregoire, John M.; Dover, R. B. van; Jin Jing; Di Salvo, Francis J.; Abruna, Hector D. [Department of Physics, Cornell University, Ithaca, New York 14853 (United States) and Cornell Fuel Cell Institute, Cornell University, Ithaca, New York 14853 (United States); Department of Materials Science and Engineering, Cornell University, Ithaca, New York 14853 (United States) and Cornell Fuel Cell Institute, Cornell University, Ithaca, New York 14853 (United States); Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853 (United States) and Cornell Fuel Cell Institute, Cornell University, Ithaca, New York 14853 (United States)

2007-07-15T23:59:59.000Z

31

High-Throughput Screen of Natural Product Libraries for Hsp90 Inhibitors  

E-Print Network [OSTI]

and negative controls to make the calculation. Robust statistics [32], which minimizes the effects of outliers on the statistical analysis, were used to calculate the median, robust standard deviation (rSD) and the robust percent coefficient of variance (%r....041 13 rSD). The Microsource compounds were part of a previously published screen [29] that had a Z-factor of 0.62 0.09. The Z-factors for the TimTec and Analyticon screens were 0.77 0.18 and 0.64 0.14, respectively. The %rCV for the screens...

Davenport, Jason; Blach, Maurie; Galam, Lakshmi; Girgis, Antwan; Hall, Jessica; Blagg, Brian S. J.; Matts, Robert L.

2014-03-03T23:59:59.000Z

32

High Throughput Combinatorial Screening of Biometic Metal-Organic Materials for Military Hydrogen-Storage Materials (New Joint Miami U/NREL DoD/DLA Project) (presentation)  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Miami University/NREL DoD/DLA Project Miami University/NREL DoD/DLA Project High throughput combinatorial screening of biomimetic metal-organic materials for military hydrogen-storage applications Philip Parilla - NREL Joe Zhou, Dan Zhao - Miami U, Ohio Jeff Blackburn, Kevin O'Neill, Lin Simpson, Mike Heben - NREL Outline * Miami/NREL Project - Synthesis (Miami) - High Throughput Characterization (NREL) - Other Characterization * Other High Throughput Activities (NREL) - Parallel Sieverts - Parallel Gravimetric * Final Comments Overview of Miami/NREL Project * Goals - Development of H 2 storage materials based on MOFs, targeting 15 kJ/mole binding energy and high density of H 2 sites - Development of optical-based detection of adsorbed H 2 allowing rapid screening of samples * Approach - Combinatorial MOFs synthesis involving 8

33

High-Throughput Chemical Screening for Antivirulence Developmental Phenotypes in Trypanosoma brucei  

Science Journals Connector (OSTI)

...S. A. 108 :10568-10573. doi: 10.1073/pnas.1105622108 . 13. ET Kamau , AR Srinivasan, MJ Brown, MG Fair, EJ Caraher, and JP Boyle. 2012. A focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii...

Paula MacGregor; Alasdair Ivens; Steven Shave; Iain Collie; David Gray; Manfred Auer; Keith R. Matthews

2014-01-17T23:59:59.000Z

34

Exploiting Domain Knowledge for Improved Quantitative High-Throughput Screening Curve Fitting  

Science Journals Connector (OSTI)

One popular measure of curve-fitting (or regression) performance obtained from the REC curve is its area over the curve (AOC):The AOC is the area between a curve and the horizontal line at unit accuracy; a smaller AOC is desirable. ... The AOC is a reasonable estimate of the mean absolute error (MAE). ... This scatter plot compares the AOC (eq 10) for the LS- and DK-fitter techniques for all 43 qHTS screens considered in this study. ...

Charles Bergeron; Gregory Moore; Michael Krein; Curt M. Breneman; Kristin P. Bennett

2011-10-14T23:59:59.000Z

35

Integrated microfluidic device for single-cell high throughput screening in dynamic gene expression analysis  

E-Print Network [OSTI]

P.J. , & Lee, L.P. , Microfluidics-based systems biology.T.M. & Quake, S.R. , Microfluidics: Fluid physics at theand applications of microfluidics in biology. Annu Rev

Hui, Lawrence Kwan Yeung

2008-01-01T23:59:59.000Z

36

Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System  

E-Print Network [OSTI]

This thesis presents the development of a high-throughput microfluidic impedance spectroscopy platform for electrically detecting analyzing impedance measurements of non-contact and label free microdroplets. This microfluidic impedance spectroscopy...

Sobahi, Nebras MohammedKamal A.

2014-07-22T23:59:59.000Z

37

A High-Throughput 3-D X-ray Microtomography System with Real-Time 3-D  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Throughput 3-D X-ray Microtomography System with Real-Time 3-D Throughput 3-D X-ray Microtomography System with Real-Time 3-D Reconstruction A high-throughput x-ray microtomography system (XMS) that can acquire, reconstruct, and interactively display rendered 3-D images of a sample at micrometer-scale resolution within minutes has been developed at Advanced Photon Source (APS) beamline 2-BM, which is managed by the Synchrotron Radiation Instrumentation Collaborative Access Team (SRI-CAT). This system could bring better understanding of an array of scientific and technological problems, ranging from failure in microelectronic devices to structures in biological samples. A rendered image from a three-dimensional tomographic reconstruction of a cricket, obtained with the x-ray microtomography system. The image has been digitally cut at different planes to show the internal structures of the cricket's head.

38

Development of High-throughput and Robust Microfluidic Live Cell Assay Platforms for Combination Drug and Toxin Screening  

E-Print Network [OSTI]

was a circular chamber with cell-trapping sieves. This 576-chamber microfluidic array was used to screen three cell types (BALB/3T3, HeLa, and bovine endothelial cells) against a panel of five toxins (digitonin, saponin, CoCl2, NiCl2, acrolein...

Wang, Han

2012-02-14T23:59:59.000Z

39

High Throughput Web Inspection System using Time-stretch Real-time Imaging  

E-Print Network [OSTI]

successfully report a dark-field web inspection system withsample substrate for our dark-field web inspection systemweb inspection system exploiting time- stretch and utilizing the merits coming from dark-

Kim, Chanju

2013-01-01T23:59:59.000Z

40

Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin  

Science Journals Connector (OSTI)

Abstract We aimed to develop a high-throughput screening (HTS) system for preliminary predictions of human skin permeability by using an artificial membrane that can mimic the permeation behaviour of lipophilic and hydrophilic compounds across the human skin. In this study, we synthesized a copolymer containing poly(dimethylsiloxane) (PDMS) and poly(ethylene glycol) (PEG) 6000 and impregnated it onto a supportive membrane filter to prepare a PDMS/PEG 6000 copolymer-impregnated membrane. In addition, we synthesized another polymer without PEG units and used it to prepare an impregnated membrane for determining the role of PEG 6000 units in the PDMS/PEG 6000 copolymer-impregnated membrane. The permeation characteristics of the impregnated membranes were evaluated on the basis of the permeability coefficients of 12 model compounds with different lipophilicities, by using a 2-chamber diffusion cell, and these permeability coefficients were compared with those across the human skin. We obtained a good correlation between the permeability coefficients across the PDMS/PEG 6000 copolymer-impregnated membrane and human skin. Further, we evaluated the permeation characteristics of a 96-well plate model of the PDMS/PEG 6000 copolymer by using 6 model compounds. We obtained an ideal correlation between the permeability coefficients across the PDMS/PEG 6000 copolymer using a 96-well plate and those across the human skin. Thus, the PDMS/PEG 6000 copolymer would be a good candidate for preliminary evaluation of the permeability of lipophilic and hydrophilic compounds across the human skin.

Ryotaro Miki; Yasuna Ichitsuka; Takumi Yamada; Soichiro Kimura; Yuya Egawa; Toshinobu Seki; Kazuhiko Juni; Hideo Ueda; Yasunori Morimoto

2015-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

High throughput optical scanner  

DOE Patents [OSTI]

A scanning apparatus is provided to obtain automated, rapid and sensitive scanning of substrate fluorescence, optical density or phosphorescence. The scanner uses a constant path length optical train, which enables the combination of a moving beam for high speed scanning with phase-sensitive detection for noise reduction, comprising a light source, a scanning mirror to receive light from the light source and sweep it across a steering mirror, a steering mirror to receive light from the scanning mirror and reflect it to the substrate, whereby it is swept across the substrate along a scan arc, and a photodetector to receive emitted or scattered light from the substrate, wherein the optical path length from the light source to the photodetector is substantially constant throughout the sweep across the substrate. The optical train can further include a waveguide or mirror to collect emitted or scattered light from the substrate and direct it to the photodetector. For phase-sensitive detection the light source is intensity modulated and the detector is connected to phase-sensitive detection electronics. A scanner using a substrate translator is also provided. For two dimensional imaging the substrate is translated in one dimension while the scanning mirror scans the beam in a second dimension. For a high throughput scanner, stacks of substrates are loaded onto a conveyor belt from a tray feeder.

Basiji, David A. (Seattle, WA); van den Engh, Gerrit J. (Seattle, WA)

2001-01-01T23:59:59.000Z

42

High-Throughput Screening for Functional Adenosine to Inosine RNA Editing Systems  

E-Print Network [OSTI]

and Peter A. Beal* Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah sequence changes to maintain an open reading frame and create a stop codon *Corresponding author, beal

Beal, Peter A.

43

494 IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS, VOL. 13, NO. 4, APRIL 2005 Memory Sub-Banking Scheme for High Throughput  

E-Print Network [OSTI]

decoding latency, and reduced memory energy consumption. Our contributions include deriva- tion, and energy consumption and provide a tradeoff analysis between the different parameters. The main implementations (both single port and dual port) of the SW SISO decoder that achieves high throughput, low

Kambhampati, Subbarao

44

High-Throughput and Combinatorial Screening  

E-Print Network [OSTI]

, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL Theory guidance: Monte Carlo (MC) technique provides minimum energy structures for subsequent enthalpy (Germany), Stockholm University (Sweden), IFE (Norway), SRNL (USA), U. Tohoku, AIST (Japan) #12;High

45

High Throughput Single Molecule Investigation of Transcription  

E-Print Network [OSTI]

genomic DNA based on single-molecule detection. Analyticalmapping: a novel, single- molecule approach to genomic2011). High-throughput single-molecule optofluidic analysis.

Kim, Soohong

2012-01-01T23:59:59.000Z

46

Graphene oxide-based micropatterns via high-throughput multiphoton-induced reduction and ablation  

Science Journals Connector (OSTI)

In this study, a developed temporal focusing-based femtosecond laser system provides high-throughput multiphoton-induced reduction and ablation of graphene oxide (GO) films. Integrated...

Li, Yi-Cheng; Yeh, Te-Fu; Huang, Hsin-Chieh; Chang, Hsin-Yu; Lin, Chun-Yu; Cheng, Li-Chung; Chang, Chia-Yuan; Teng, Hsisheng; Chen, Shean-Jen

2014-01-01T23:59:59.000Z

47

High-throughput Process Development  

E-Print Network [OSTI]

.2 Screening experiments in PreDictor plates vs small-scale columns....................................5 1 Chromatography Principles and Methods 18-1022-29 Antibody Purification Handbook 18-1037-46 Ion Exchange Protein Purification Handbook Principles and Methods 18-1142-75 Protein Purification Handbook 18

Lebendiker, Mario

48

Potential of High-Throughput Experimentation with Ammonia Borane...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Potential of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials (presentation) Potential of High-Throughput Experimentation with Ammonia Borane...

49

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

Broader source: Energy.gov (indexed) [DOE]

High-ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D (presentation) High-ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D (presentation)...

50

High-throughput metal nanoparticle catalysis by pulsed laser ablation Selim Senkan a,*, Michael Kahn a  

E-Print Network [OSTI]

High-throughput metal nanoparticle catalysis by pulsed laser ablation Selim Senkan a,*, Michael online 18 July 2006 Abstract A high-throughput pulsed laser ablation (HT-PLA) system was developed-TEM) and energy dispersive X-ray (EDX) spectroscopy, respectively. The supported nanoparticles created by HT

Senkan, Selim M.

51

A high-throughput infrastructure for density functional theory calculations Anubhav Jain, Geoffroy Hautier, Charles J. Moore, Shyue Ping Ong, Christopher C. Fischer,  

E-Print Network [OSTI]

A high-throughput infrastructure for density functional theory calculations Anubhav Jain, Geoffroy-throughput computation Density functional theory Materials screening GGA Formation enthalpies a b s t r a c t The use of high-throughput density functional theory (DFT) calculations to screen for new materials and conduct

Ceder, Gerbrand

52

Development of FRET-based Technologies for Dynamic and Quantitative Measurement of Protein-protein Interactions and High-throughput Screening of Small Chemical Inhibitors of the SUMO Pathway  

E-Print Network [OSTI]

throughput platform to screen small chemical compounds thatscreening platforms to look for small chemical inhibitorsplatform provides a new strategy to identify small chemical

Song, Yang

2011-01-01T23:59:59.000Z

53

Hydrogen Storage Materials Discovery via High Throughput Ball Milling and Gas Sorption  

Science Journals Connector (OSTI)

The lack of a high capacity hydrogen storage material is a major barrier to the implementation of the hydrogen economy. To accelerate discovery of such materials, we have developed a high-throughput workflow for screening of hydrogen storage materials in ...

Bin Li; Steven S. Kaye; Conor Riley; Doron Greenberg; Daniel Galang; Mark S. Bailey

2012-05-22T23:59:59.000Z

54

A microfluidic platform for high-throughput multiplexed protein quantitation  

E-Print Network [OSTI]

We present a high-throughput microfluidic platform capable of quantitating up to 384 biomarkers in 4 distinct samples by immunoassay. The microfluidic device contains 384 unit cells, which can be individually programmed with pairs of capture and detection antibody. Samples are quantitated in each unit cell by four independent MITOMI detection areas, allowing four samples to be analyzed in parallel for a total of 1,536 assays per device. We show that the device can be pre-assembled and stored for weeks at elevated temperature and we performed proof-of-concept experiments simultaneously quantitating IL-6, IL-1\\b{eta}, TNF-{\\alpha}, PSA, and GFP. Finally, we show that the platform can be used to identify functional antibody combinations by screening 64 antibody combinations requiring up to 384 unique assays per device.

Volpetti, Francesca; Maerkl, Sebastian

2014-01-01T23:59:59.000Z

55

Combinatorial Materials Research Applied to the Development of New Surface Coatings I:? A Multiwell Plate Screening Method for the High-Throughput Assessment of Bacterial Biofilm Retention on Surfaces  

Science Journals Connector (OSTI)

The screening process involves (1) multiwell plate modifications for coating deposition, (2) deposition of combinatorial coating libraries via an automated liquid dispensing robot, (3) coating thickness measurements of cured coatings, (4) preconditioning of coatings via immersion in deionized water, (5) bacterial incubation, (6) plate processing, and (7) data analysis for identification of promising candidates. ... This clearly perceptible increase recorded since 1982, may be attributable to the growing use of copper paints subsequent to the antifouling paint regulations adopted in 1982. ... that can be applied with both lethal and sublethal effect criteria for the detn. of toxic stress from leaches of painted surfaces. ...

Shane J. Stafslien; James A. Bahr; Jason M. Feser; Jonathan C. Weisz; Bret J. Chisholm; Thomas E. Ready; Philip Boudjouk

2005-12-31T23:59:59.000Z

56

High Throughput Operando Studies using Fourier Transform Infrared...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Throughput Operando Studies using Fourier Transform Infrared Imaging and Raman Spectroscopy. High Throughput Operando Studies using Fourier Transform Infrared Imaging and Raman...

57

Potential of High-Throughput Experimentation with Ammonia Borane...  

Broader source: Energy.gov (indexed) [DOE]

of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials Jonathan L. Male Pacific Northwest National Laboratory June 26, 2006 US Department of Energy...

58

ORIGINAL ARTICLE Combining high-throughput sequencing with fruit  

E-Print Network [OSTI]

ORIGINAL ARTICLE Combining high-throughput sequencing with fruit body surveys reveals contrasting communities were mostly confined to fruit bodies, whereas mycelial interactions were studied in the laboratory. Here we combine high-throughput sequencing with a fruit body inventory to study simultaneously mycelial

Bruns, Tom

59

High Throughput Combinatorial Screening of Biometic Metal-Organic...  

Broader source: Energy.gov (indexed) [DOE]

O O OH O HO OH O Co V 3+ Cr 3+ Mn 2+ Fe 2+ Co 2+ Ni 2+ Cu 2+ Ni Pd Pt SBU metal ions bare metal Carboxylate linkers Vibrational Spectroscopy of Hydrogen Raman *H 2 in gas...

60

High-Throughput and Combinatorial Screening of Hydrogen Storage...  

Broader source: Energy.gov (indexed) [DOE]

method The sintering technique is used by groups at: U. Geneva (Switzerland), MPI (Germany), Stockholm University (Sweden), IFE (Norway), SRNL (USA), U. Tohoku, AIST (Japan)...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

High Throughput/Combinatorial Screening of Hydrogen Storage Materials (presentation)  

Broader source: Energy.gov [DOE]

Presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

62

FastForward: High-Throughput Dual-Radio Streaming Gholamhossein Ekbatanifard  

E-Print Network [OSTI]

amount of data at high throughput and/or low latency. For example, structural health of the Golden Gate end-to-end throughput is limited to 1/2 the radio capacity. To bridge this performance gap we present Bridge was sampled at 1 KHz in [1]. Brimon, a railway monitoring system, generates about 7 KB in each

Kuzmanov, Georgi

63

Application of high-throughput computing in bioinformatics  

Science Journals Connector (OSTI)

...Issue New science from high-performance computing organized by Richard Catlow...bioinformatics database|high-performance computing| Application of high-throughput...bioinformatics database; high-performance computing 1. Introduction Organizing...

2002-01-01T23:59:59.000Z

64

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

Broader source: Energy.gov (indexed) [DOE]

Storage (New DoDDLA Project), Ali T-Raissi, University of Central Florida, Florida Solar Energy Center High-Throughput Methodology for Discovery of Metal-Organic Frameworks...

65

High-throughput routing for multi-hop wireless networks  

E-Print Network [OSTI]

The expected transmission count (ETX) metric is a new route metric for finding high-throughput paths in multi-hop wireless networks. The ETX of a path is the expected total number of packet transmissions (including ...

De Couto, Douglas S. J. (Douglas Seraphim James), 1975-

2004-01-01T23:59:59.000Z

66

High-Throughput Characterization of Porous Materials Using Graphics...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

High-Throughput Characterization of Porous Materials Using Graphics Processing Units Previous Next List J. Kim, R. L. Martin, O. Rubel, M. Haranczyk, and B. Smit, J. Chem. Theory...

67

Robust, High-Throughput Analysis of Protein Structures  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of even the simplest of organisms. Hura et al. have developed a high-throughput protein pipeline that could expedite protein analysis by trading atomic-level detail for speed and...

68

Robust, High-Throughput Analysis of Protein Structures  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Robust, High-Throughput Analysis of Protein Structures Print Robust, High-Throughput Analysis of Protein Structures Print Scientists have developed a fast and efficient way to determine the structure of proteins, shortening a process that often takes years into a matter of days. The Structurally Integrated BiologY for Life Sciences (SIBYLS) beamline at the ALS has implemented the world's highest-throughput biological-solution x-ray scattering beamline enabling genomic-scale protein-structure characterization. Coupling brilliant x rays from one of the superconducting bend magnets at the ALS to liquid-handling robotics has enabled the collection of 96 samples in 4 hours. Importantly, the sample format and the amount of material required are practical for most biological problems. The beamline's high-throughput capability is set to have a large impact on many fields that require genomic-scale information, such as Berkeley Lab's bioenergy efforts and cancer biology studies.

69

Hypercontraction and Drosophila : a model system for the study of human myopathies  

E-Print Network [OSTI]

Currently, there are no therapeutic interventions which fully alleviate the defects associated with muscular dystrophies and cardiomyopathies. Development of model systems in which to utilize high-throughput screens for ...

Montana, Enrico Sakai

2005-01-01T23:59:59.000Z

70

High Throughput Spectrum-aware Routing for Cognitive Radio Networks  

E-Print Network [OSTI]

High Throughput Spectrum-aware Routing for Cognitive Radio Networks Ashwin Sampath, Lei Yang, Lili, wireless nodes equipped with cognitive radios [11] do not operate on statically as- signed spectrum who own the spectrum, e.g. analog TV broadcast stations. Such flexibility means cognitive radios can

Zhao, Ben Y.

71

High Throughput Spectrumaware Routing for Cognitive Radio Networks  

E-Print Network [OSTI]

High Throughput Spectrum­aware Routing for Cognitive Radio Networks Ashwin Sampath, Lei Yang, Lili, wireless nodes equipped with cognitive radios [11] do not operate on statically as­ signed spectrum. Instead, they identify and use locally unused licensed spectrum while avoiding disruptions to legacy users

Zhao, Ben Y.

72

The JCSG high-throughput structural biology pipeline  

Science Journals Connector (OSTI)

The Joint Center for Structural Genomics high-throughput structural biology pipeline has delivered more than 1000 structures to the community over the past ten years and has made a significant contribution to the overall goal of the NIH Protein Structure Initiative (PSI) of expanding structural coverage of the protein universe.

Elsliger, M.-A.

2010-09-30T23:59:59.000Z

73

Abstract 3967: The Cancer Genome Project high throughput analysis pipeline  

Science Journals Connector (OSTI)

...Genome Project high throughput analysis pipeline Adam P. Butler 1 Jon W. Teague 1 Keiran...somatic changes. We have built an analysis pipeline to track and analyse large numbers of...externally available tools. The analysis pipeline is built around a 2,000 node compute...

Adam P. Butler; Jon W. Teague; Keiran M. Raine; Andrew Menzies; David Jones; John Marshall; Jon Hinton; Serge Dronov; John Gamble; Lucy Stebbings; Alagu Jayakumar; Catherine Leroy; Ultan McDermott; Michael R. Stratton; Peter Campbell; Andy Futreal

2012-06-04T23:59:59.000Z

74

High throughput liquid absorption preconcentrator sampling instrument  

DOE Patents [OSTI]

A system for detecting trace concentrations of an analyte in air includes a preconcentrator for the analyte and an analyte detector. The preconcentrator includes an elongated tubular container comprising a wettable material. The wettable material is continuously wetted with an analyte-sorbing liquid which flows from one part of the container to a lower end. Sampled air flows through the container in contact with the wetted material with a swirling motion which results in efficient transfer of analyte vapors or aerosol particles to the sorbing liquid and preconcentration of traces of analyte in the liquid. The preconcentrated traces of analyte may be either detected within the container or removed therefrom for injection into a separate detection means or for subsequent analysis. 12 figs.

Zaromb, S.; Bozen, R.M.

1992-12-22T23:59:59.000Z

75

High throughput lessons from the LHC experience.Johnston.TNC2013  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

high throughput in widely distributed data high throughput in widely distributed data management and analysis systems: Lessons from the LHC William E. Johnston ESnet, Lawrence Berkeley National Laboratory e-mail: wej@es.net Eli Dart ESnet, Lawrence Berkeley National Laboratory e-mail: dart@es.net Michael Ernst RHIC and ATLAS Computing Facility, Brookhaven National Laboratory e-mail: mernst@bnl.gov Brian Tierney ESnet, Lawrence Berkeley National Laboratory e-mail: bltierney@es.net Paper type Technical paper Abstract Today's large-scale science projects all involve world-wide collaborations that must routinely move 10s of petabytes per year between international sites in order to be successful. This is true for the two largest experiments at the Large Hadron Collider (LHC) at CERN - ATLAS and CMS - and for the climate science

76

Updating Interconnection Screens for PV System Integration  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Abraham Ellis, Roger Hill Sandia National Laboratories Tom Key, Kristen Nicole, Jeff Smith Electric Power Research Institute Updating Interconnection Screens for PV System...

77

A review of the theory, methods and recent applications of high-throughput single-cell droplet microfluidics  

Science Journals Connector (OSTI)

Most cell biology experiments are performed in bulk cell suspensions where cell secretions become diluted and mixed in a contiguous sample. Confinement of single cells to small, picoliter-sized droplets within a continuous phase of oil provides chemical isolation of each cell, creating individual microreactors where rare cell qualities are highlighted and otherwise undetectable signals can be concentrated to measurable levels. Recent work in microfluidics has yielded methods for the encapsulation of cells in aqueous droplets and hydrogels at kilohertz rates, creating the potential for millions of parallel single-cell experiments. However, commercial applications of high-throughput microdroplet generation and downstream sensing and actuation methods are still emerging for cells. Using fluorescence-activated cell sorting (FACS) as a benchmark for commercially available high-throughput screening, this focused review discusses the fluid physics of droplet formation, methods for cell encapsulation in liquids and hydrogels, sensors and actuators and notable biological applications of high-throughput single-cell droplet microfluidics.

Todd P Lagus; Jon F Edd

2013-01-01T23:59:59.000Z

78

Macromolecular Crystallography conventional and high-throughput methods  

SciTech Connect (OSTI)

High-throughput data collection requires the seamless interoperation of various hardware components. User-supplied descriptions of protein crystals must also be directly linked with the diffraction data. Such linkages can be achieved efficiently with computer databases. A database that tracks production of the protein samples, crystallization, and diffraction from the resultant crystals serves as the glue that holds the entire gene-to-structure process together. This chapter begins by discussing data collection processes and hardware. It then illustrates how a well-constructed database ensures information flow through the steps of data acquisition. Such a database allows synchrotron beamline measurements to be directly and efficiently integrated into the process of protein crystallographic structure determination.

Wasserman, Stephen R.; Smith, David W.; D'Amico, Kevin L.; Koss, John W.; Morisco, Laura L.; Burley, Stephen K.

2007-09-27T23:59:59.000Z

79

Updating Interconnection Screens for PV System Integration  

SciTech Connect (OSTI)

This white paper evaluates the origins and usefulness of the capacity penetration screen, offer short-term solutions which could effectively allow fast-track interconnection to many PV system applications, and considers longer-term solutions for increasing PV deployment levels in a safe and reliable manner while reducing or eliminating the emphasis on the penetration screen. Short-term and longer-term alternatives approaches are offered as examples; however, specific modifications to screening procedures should be discussed with stakeholders and must ultimately be adopted by state and federal regulatory bodies.

Coddington, M.; Mather, B.; Kroposki, B.; Lynn, K.; Razon, A.; Ellis, A.; Hill, R.; Key, T.; Nicole, K.; Smith, J.

2012-02-01T23:59:59.000Z

80

A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay  

SciTech Connect (OSTI)

The National Research Council has outlined the need for non-mammalian toxicological models to test the potential health effects of a large number of chemicals while also reducing the use of traditional animal models. The nematode Caenorhabditis elegans is an attractive alternative model because of its well-characterized and evolutionarily conserved biology, low cost, and ability to be used in high-throughput screening. A high-throughput method is described for quantifying the reproductive capacity of C. elegans exposed to chemicals for 48 h from the last larval stage (L4) to adulthood using a COPAS Biosort. Initially, the effects of exposure conditions that could influence reproduction were defined. Concentrations of DMSO vehicle {<=} 1% did not affect reproduction. Previous studies indicated that C. elegans may be influenced by exposure to low pH conditions. At pHs greater than 4.5, C. elegans reproduction was not affected; however below this pH there was a significant decrease in the number of offspring. Cadmium chloride was chosen as a model toxicant to verify that automated measurements were comparable to those of traditional observational studies. EC{sub 50} values for cadmium for automated measurements (176-192 {mu}M) were comparable to those previously reported for a 72-h exposure using manual counting (151 {mu}M). The toxicity of seven test toxicants on C. elegans reproduction was highly correlative with rodent lethality suggesting that this assay may be useful in predicting the potential toxicity of chemicals in other organisms.

Boyd, Windy A. [Biomolecular Screening Branch, National Toxicology Program, Research Triangle Park, NC 27709 (United States); McBride, Sandra J.; Rice, Julie R.; Snyder, Daniel W. [Biomolecular Screening Branch, National Toxicology Program, Research Triangle Park, NC 27709 (United States); Freedman, Jonathan H., E-mail: freedma1@niehs.nih.go [Biomolecular Screening Branch, National Toxicology Program, Research Triangle Park, NC 27709 (United States); Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709 (United States)

2010-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide.  

E-Print Network [OSTI]

??Abstract Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide by Dennis Pleskot Master of Science, Graduate Program in Materials Science and Engineering University (more)

Pleskot, Dennis

2013-01-01T23:59:59.000Z

82

The high-throughput protein-to-structure pipeline at SECSG  

Science Journals Connector (OSTI)

The high-throughput crystal structure determination pipeline at Southeast Collaboratory for Structural Genomics, a pilot center of the National Institutes of Health Protein Structure Initiative, is described.

Liu, Z.-J.

2005-05-26T23:59:59.000Z

83

High-Throughput Microfluidics and Ultrafast Optics for in vivo Compound/Genetic Discoveries  

Science Journals Connector (OSTI)

We developed microfluidic and ultrafast optical technologies that enable high-throughput whole-animal neural regeneration studies. These technologies allow automated and rapid...

Rohde, Chris; Gilleland, Cody; Samara, Chrysanthi; Yanik, Mehmet F

84

Test bed for a high throughput supersonic chemical oxygen - iodine laser  

SciTech Connect (OSTI)

The paper reports the development of a test bed for a chemical oxygen - iodine laser based on a high throughput jet flow singlet oxygen generator (JSOG). The system provides vertical singlet oxygen extraction followed by horizontal orientation of subsequent subsystems. This design enables the study of flow complexities and engineering aspects of a distributed weight system as an input for mobile and other platform-mounted systems developed for large scale power levels. The system under consideration is modular and consists of twin SOGs, plenum and supersonic nozzle modules, with the active medium produced in the laser cavity. The maximal chlorine flow rate for the laser is {approx}1.5 mole s{sup -1} achieving a typical chemical efficiency of about 18%. (lasers)

Singhal, Gaurav; Mainuddin; Rajesh, R; Varshney, A K; Dohare, R K; Kumar, Sanjeev; Singh, V K; Kumar, Ashwani; Verma, Avinash C; Arora, B S; Chaturvedi, M K; Tyagi, R K; Dawar, A L

2011-05-31T23:59:59.000Z

85

Abstract 5143: From sequencing data to mutation spectra: a high throughput analysis pipeline.  

Science Journals Connector (OSTI)

...spectra: a high throughput analysis pipeline. David Jones Adam P. Butler Jon W...developed a high throughput analysis pipeline utilising a suite of analysis software...development is focussed on converting the pipeline to produce and store VCF output, incorporate...

David Jones; Adam P. Butler; Jon W. Teague; Keiran M. Raine; Andrew Menzies; John Marshall; Jonathan Hinton; Serge Dronov; Lucy Stebbings; Alagu Jayakumar; Catherine Leroy; Jorge Zamora; Manasa Ramakrishna; Elli Papaemmanuil; Helen Davies; Susanna L. Cooke; Serena Nik-Zainal; Ultan McDermott; Michael R. Stratton; Peter Campbell

2013-08-14T23:59:59.000Z

86

HIGH-THROUGHPUT/COMBINATORIAL TECHNIQUES IN HYDROGEN STORAGE MATERIALS R&D WORKSHOP  

E-Print Network [OSTI]

HIGH-THROUGHPUT/COMBINATORIAL TECHNIQUES IN HYDROGEN STORAGE MATERIALS R&D WORKSHOP U.S. Department 26, 2007, DOE's Hydrogen Storage Program held a one-day High- Throughput/Combinatorial Techniques in Hydrogen Storage Materials R&D meeting to identify how to better implement high

87

Grid Workflow Software for a High-Throughput Proteome Annotation Pipeline  

E-Print Network [OSTI]

Grid Workflow Software for a High-Throughput Proteome Annotation Pipeline Adam Birnbaum1 , James-Throughput Proteome 69 Protein Data Bank [9]. Despite the advent of high throughput crystallization pipelines [25 Annotation Pipeline (iGAP) [28]. iGAP, which incorporates a number of well established bioinformatics

Bourne, Philip E.

88

High-throughput full-automatic synchrotron-based tomographic microscopy  

SciTech Connect (OSTI)

At the TOMCAT (TOmographic Microscopy and Coherent rAdiology experimenTs) beamline of the Swiss Light Source with an energy range of 8-45 keV and voxel size from 0.37 {micro}m to 7.4 {micro}m, full tomographic datasets are typically acquired in 5 to 10 min. To exploit the speed of the system and enable high-throughput studies to be performed in a fully automatic manner, a package of automation tools has been developed. The samples are automatically exchanged, aligned, moved to the correct region of interest, and scanned. This task is accomplished through the coordination of Python scripts, a robot-based sample-exchange system, sample positioning motors and a CCD camera. The tools are suited for any samples that can be mounted on a standard SEM stub, and require no specific environmental conditions. Up to 60 samples can be analyzed at a time without user intervention. The throughput of the system is dependent on resolution, energy and sample size, but rates of four samples per hour have been achieved with 0.74 {micro}m voxel size at 17.5 keV. The maximum intervention-free scanning time is theoretically unlimited, and in practice experiments have been running unattended as long as 53 h (the average beam time allocation at TOMCAT is 48 h per user). The system is the first fully automated high-throughput tomography station: mounting samples, finding regions of interest, scanning and reconstructing can be performed without user intervention. The system also includes many features which accelerate and simplify the process of tomographic microscopy.

Mader, Kevin; Marone, Federica; Hintermller, Christoph; Mikuljan, Gordan; Isenegger, Andreas; Stampanoni, Marco (SLS)

2011-08-16T23:59:59.000Z

89

Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi  

E-Print Network [OSTI]

Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG).

David Abdurachmanov; Brian Bockelman; Peter Elmer; Giulio Eulisse; Robert Knight; Shahzad Muzaffar

2014-10-10T23:59:59.000Z

90

Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi  

E-Print Network [OSTI]

Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG).

Abdurachmanov, David; Elmer, Peter; Eulisse, Giulio; Knight, Robert; Muzaffar, Shahzad

2014-01-01T23:59:59.000Z

91

Towards Chip Scale Liquid Chromatography and High Throughput Immunosensing  

SciTech Connect (OSTI)

This work describes several research projects aimed towards developing new instruments and novel methods for high throughput chemical and biological analysis. Approaches are taken in two directions. The first direction takes advantage of well-established semiconductor fabrication techniques and applies them to miniaturize instruments that are workhorses in analytical laboratories. Specifically, the first part of this work focused on the development of micropumps and microvalves for controlled fluid delivery. The mechanism of these micropumps and microvalves relies on the electrochemically-induced surface tension change at a mercury/electrolyte interface. A miniaturized flow injection analysis device was integrated and flow injection analyses were demonstrated. In the second part of this work, microfluidic chips were also designed, fabricated, and tested. Separations of two fluorescent dyes were demonstrated in microfabricated channels, based on an open-tubular liquid chromatography (OT LC) or an electrochemically-modulated liquid chromatography (EMLC) format. A reduction in instrument size can potentially increase analysis speed, and allow exceedingly small amounts of sample to be analyzed under diverse separation conditions. The second direction explores the surface enhanced Raman spectroscopy (SERS) as a signal transduction method for immunoassay analysis. It takes advantage of the improved detection sensitivity as a result of surface enhancement on colloidal gold, the narrow width of Raman band, and the stability of Raman scattering signals to distinguish several different species simultaneously without exploiting spatially-separated addresses on a biochip. By labeling gold nanoparticles with different Raman reporters in conjunction with different detection antibodies, a simultaneous detection of a dual-analyte immunoassay was demonstrated. Using this scheme for quantitative analysis was also studied and preliminary dose-response curves from an immunoassay of a mo del antigen were obtained. Simultaneous detection of several analytes at the same address can potentially increase the analysis speed, and can further expand the analysis capability of a microarray chip.

Ni, J.

2000-09-21T23:59:59.000Z

92

Metal Organic Framework Research: High Throughput Discovery of Robust Metal Organic Framework for CO2 Capture  

SciTech Connect (OSTI)

IMPACCT Project: LBNL is developing a method for identifying the best metal organic frameworks for use in capturing CO2 from the flue gas of coal-fired power plants. Metal organic frameworks are porous, crystalline compounds that, based on their chemical structure, vary considerably in terms of their capacity to grab hold of passing CO2 molecules and their ability to withstand the harsh conditions found in the gas exhaust of coal-fired power plants. Owing primarily to their high tunability, metal organic frameworks can have an incredibly wide range of different chemical and physical properties, so identifying the best to use for CO2 capture and storage can be a difficult task. LBNL uses high-throughput instrumentation to analyze nearly 100 materials at a time, screening them for the characteristics that optimize their ability to selectively adsorb CO2 from coal exhaust. Their work will identify the most promising frameworks and accelerate their large-scale commercial development to benefit further research into reducing the cost of CO2 capture and storage.

None

2010-08-01T23:59:59.000Z

93

A microfluidic device for high throughput bacterial biofilm studies Jeongyun Kim,a  

E-Print Network [OSTI]

A microfluidic device for high throughput bacterial biofilm studies Jeongyun Kim,a Manjunath Hegde of biofilm community formation. Here, we describe the development of a PDMS-based two-layer microfluidic flow

Wood, Thomas K.

94

E-Print Network 3.0 - alphascreen high-throughput assay Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Session Chair: James F. Leary 3:20-4:05 James F. Leary, "High throughput cell analysis... French and Jiyan Chen Long Lifetime Measurements in High ... Source: Xu, X. Nancy -...

95

High-Throughput/Combinatorial Techniques in Hydrogen Storage Materials R&D  

Broader source: Energy.gov [DOE]

On June 26, 2007 the Hydrogen Storage Program of the U.S. Department of Energy (DOE) held a one-day meeting to identify how to better implement high-throughput/combinatorial techniques to benefit...

96

An instrument for high-throughput measurements of fiber mechanical properties  

E-Print Network [OSTI]

In this thesis, an instrument is designed and constructed for the purpose of measuring the mechanical properties of single fibers. The instrument is intended to provide high throughput measurement of single fiber geometric ...

Kristofek, Grant William, 1980-

2005-01-01T23:59:59.000Z

97

Engineering a single cell microarray platform for high throughput DNA damage and repair analysis  

E-Print Network [OSTI]

DNA damage contributes to cancer, aging, and heritable diseases. Ironically, DNA damaging agents are also commonly used in current cancer treatment. We therefore need robust, high throughput, and inexpensive tools for ...

Weingeist, David McGregor

2012-01-01T23:59:59.000Z

98

Microelectroporation device for genomic screening  

DOE Patents [OSTI]

We have developed an microelectroporation device that combines microarrays of oligonucleotides, microfluidic channels, and electroporation for cell transfection and high-throughput screening applications (e.g. RNA interference screens). Microarrays allow the deposition of thousands of different oligonucleotides in microscopic spots. Microfluidic channels and microwells enable efficient loading of cells into the device and prevent cross-contamination between different oligonucleotides spots. Electroporation allows optimal transfection of nucleic acids into cells (especially hard-to-transfect cells such as primary cells) by minimizing cell death while maximizing transfection efficiency. This invention has the advantage of a higher throughput and lower cost, while preventing cross-contamination compared to conventional screening technologies. Moreover, this device does not require bulky robotic liquid handling equipment and is inherently safer given that it is a closed system.

Perroud, Thomas D.; Renzi, Ronald F.; Negrete, Oscar; Claudnic, Mark R.

2014-09-09T23:59:59.000Z

99

Generalized Schemes for High Throughput Manipulation of the Desulfovibrio vulgaris Hildenborough Genome.  

SciTech Connect (OSTI)

The ability to conduct advanced functional genomic studies of the thousands of 38 sequenced bacteria has been hampered by the lack of available tools for making high39 throughput chromosomal manipulations in a systematic manner that can be applied across 40 diverse species. In this work, we highlight the use of synthetic biological tools to 41 assemble custom suicide vectors with reusable and interchangeable DNA parts to 42 facilitate chromosomal modification at designated loci. These constructs enable an array 43 of downstream applications including gene replacement and creation of gene fusions with 44 affinity purification or localization tags. We employed this approach to engineer 45 chromosomal modifications in a bacterium that has previously proven difficult to 46 manipulate genetically, Desulfovibrio vulgaris Hildenborough, to generate a library of 47 662 strains. Furthermore, we demonstrate how these modifications can be used for 48 examining metabolic pathways, protein-protein interactions, and protein localization. The 49 ubiquity of suicide constructs in gene replacement throughout biology suggests that this 50 approach can be applied to engineer a broad range of species for a diverse array of 51 systems biological applications and is amenable to high-throughput implementation.

Chhabra, Swapnil [Lawrence Berkeley National Laboratory (LBNL); Butland, Gareth [Lawrence Berkeley National Laboratory (LBNL); Elias, Dwayne A [ORNL; Chandonia, John-Marc [Lawrence Berkeley National Laboratory (LBNL); Fok, Olivia [Lawrence Berkeley National Laboratory (LBNL); Juba, tom [University of Missouri; Gorur, A. [Lawrence Berkeley National Laboratory (LBNL); Allen, S. [University of California, San Francisco; Leung, C. M. [Lawrence Berkeley National Laboratory (LBNL); Keller, Kim [University of Missouri; Reveco, S. [Lawrence Berkeley National Laboratory (LBNL); Zane, Mr. Grant M. [University of Missouri, Columbia; Semkiw, Elizabeth M. [University of Missouri; Prathapam, R. [Lawrence Berkeley National Laboratory (LBNL); Gold, B. [Lawrence Berkeley National Laboratory (LBNL); Singer, Mary [Lawrence Berkeley National Laboratory (LBNL); Ouellet, M. [Lawrence Berkeley National Laboratory (LBNL); Sazakal, E. D. [University of California, San Francisco; Jorgens, Dominique [Lawrence Berkeley National Laboratory (LBNL); Price, Morgan N. [Lawrence Berkeley National Laboratory (LBNL); Witkowska, Ewa [University of California, San Francisco; Beller, Harry R. [Lawrence Berkeley National Laboratory (LBNL); Hazen, Terry [Lawrence Berkeley National Laboratory (LBNL); Biggin, Mark D. [Lawrence Berkeley National Laboratory (LBNL); Auer, Dr. Manfred [Lawrence Berkeley National Laboratory (LBNL); Wall, Judy D. [University of Missouri; Keasling, Jay [Lawrence Berkeley National Laboratory (LBNL)

2011-01-01T23:59:59.000Z

100

A. Ford and H. Flynn: Statistical Screening of Models 273 Statistical screening of system dynamics  

E-Print Network [OSTI]

in the information spectrum in Figure 1. Hard sources include physical laws and the results of controlled experimentsA. Ford and H. Flynn: Statistical Screening of Models 273 Statistical screening of system dynamics models Andrew Forda * and Hilary Flynnb Abstract This paper describes a pragmatic method of searching

Ford, Andrew

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

A comprehensive insight into bacterial virulence in drinking water using 454 pyrosequencing and Illumina high-throughput sequencing  

Science Journals Connector (OSTI)

Abstract In order to comprehensively investigate bacterial virulence in drinking water, 454 pyrosequencing and Illumina high-throughput sequencing were used to detect potential pathogenic bacteria and virulence factors (VFs) in a full-scale drinking water treatment and distribution system. 16S rRNA gene pyrosequencing revealed high bacterial diversity in the drinking water (441586 operational taxonomic units). Bacterial diversity decreased after chlorine disinfection, but increased after pipeline distribution. ?-Proteobacteria was the most dominant taxonomic class. Alignment against the established pathogen database showed that several types of putative pathogens were present in the drinking water and Pseudomonas aeruginosa had the highest abundance (over 11 of total sequencing reads). Many pathogens disappeared after chlorine disinfection, but P. aeruginosa and Leptospira interrogans were still detected in the tap water. High-throughput sequencing revealed prevalence of various pathogenicity islands and virulence proteins in the drinking water, and translocases, transposons, Clp proteases and flagellar motor switch proteins were the predominant VFs. Both diversity and abundance of the detectable \\{VFs\\} increased after the chlorination, and decreased after the pipeline distribution. This study indicates that joint use of 454 pyrosequencing and Illumina sequencing can comprehensively characterize environmental pathogenesis, and several types of putative pathogens and various \\{VFs\\} are prevalent in drinking water.

Kailong Huang; Xu-Xiang Zhang; Peng Shi; Bing Wu; Hongqiang Ren

2014-01-01T23:59:59.000Z

102

Salvage and storage of infectious disease protein targets in the SSGCID high-throughput crystallization pathway using microfluidics  

Science Journals Connector (OSTI)

SSGCID protein crystals were salvaged and stored using the MPCS Plug Maker and CrystalCards when high-throughput traditional sitting-drop vapor diffusion initially failed.

Christensen, J.

2011-08-13T23:59:59.000Z

103

High-Throughput Computational Screening of thermal conductivity, Debye temperature and Gruneisen parameter  

E-Print Network [OSTI]

thermal properties such as the Debye temperature and the thermal conductivity of materials. We demonstrate studied for the past few decades6 . Low thermal conductivity mate- rials constitute the basis of a new and predict the thermal conductivity of differ- ent materials8,9,11­16 . Such evaluation of the higher

Curtarolo, Stefano

104

Integrated microfluidic device for single-cell high throughput screening in dynamic gene expression analysis  

E-Print Network [OSTI]

programs (e.g. AutoCAD, Autodesk Inc. or Adobe Illustrator,such as AutoCAD 2005 (Autodesk Inc. ), and printed at 20,000Adobe) and AutoCAD (Autodesk Inc. ), printed on transparent

Hui, Lawrence Kwan Yeung

2008-01-01T23:59:59.000Z

105

Characterization of Diversity in Toxicity Mechanism Using in Vitro Cytotoxicity Assays in Quantitative High Throughput Screening  

Science Journals Connector (OSTI)

Rat renal proximal tubule cells were freshly isolated from the kidneys of six male Harlan SpragueDawley rats at age of 5660 days and weight of 220250 g by In Vitro ADMET Laboratories, LLC (Rockville, MD). ... The overall active rate for the caspase assays is significantly lower than that of the cell viability assays, which ranged from 4 to 11% for class 1a, 1b, and 2a compounds (720% for class 13). ...

Ruili Huang; Noel Southall; Ming-Hsuang Cho; Menghang Xia; James Inglese; Christopher P. Austin

2008-02-19T23:59:59.000Z

106

Using Clustering Techniques to Improve Hit Selection in High-Throughput Screening  

E-Print Network [OSTI]

control. This makes the correct identification of active compounds quite difficult. The incoherencies and Makarenkov,7 and Makarenkov et al.8,9 Another factor that influences the identification of active compounds plate or in the bulk of the data). This method is not statistically justified and can lead to some

Makarenkov, Vladimir

107

Learning from the Data:? Mining of Large High-Throughput Screening Databases  

Science Journals Connector (OSTI)

We developed a data mining approach based on an algorithm called ontology-based pattern identification (OPI) and applied it to our in-house HTS database. ... In an effort to derive relationships between anticancer compounds and biological targets, Weinstein and colleagues employed a clustered image map (CIM) approach based on compound and activity profile clustering. ...

S. Frank Yan; Frederick J. King; Yun He; Jeremy S. Caldwell; Yingyao Zhou

2006-09-28T23:59:59.000Z

108

High-Throughput in vivo Genetic and Drug Screening Using Femtosecond Laser Microsurgery and Microfluidics  

Science Journals Connector (OSTI)

We developed microfluidic devices, imaging algorithms and femtosecond laser microsurgery technologies to manipulate large numbers of small-animals on a single chip for sub-cellular...

Rohde, Christopher B; Zeng, Fei; Gilleland, Coddy; Gonzalez-Rubio, Ricardo; Angel, Matthew; Yanik, Mehmet F

109

Integrated microfluidic device for single-cell high throughput screening in dynamic gene expression analysis.  

E-Print Network [OSTI]

??Over the past decade, interest in microfluidics has surged as applications have trended towards novel biological assays. Specifically, the ability of microfluidics to parallelize cellular (more)

Hui, Lawrence Kwan Yeung

2008-01-01T23:59:59.000Z

110

PDMS-based microfluidic platforms for chemical analysis and high-throughput screening.  

E-Print Network [OSTI]

??Microfluidics, as a new interdisciplinary field, holds the promise to offer better solutionsfor analytical chemistry, bioscience, and material science etc. However, microfluidics is still in (more)

Zhou, Jianhua

2011-01-01T23:59:59.000Z

111

NSF ITR Project ABSTRACTION HIERARCHY MODELING OF HIGH-THROUGHPUT SCREENING  

E-Print Network [OSTI]

that are also integrated in the HTS line), this equipment has no proprietary control #12;software. The labeling/configuration" dialogs presented through an assay method programming application/interface used to control the entire AUTOMATION David B.Kaber & Steffen Junginger Overview: This document presents abstraction hierarchy (AH

Kaber, David B.

112

High-Throughput and Combinatorial Screening of Hydrogen Storage Materials (presentation)  

Broader source: Energy.gov [DOE]

Presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

113

An apparatus for high throughput muscle cell experimentation  

E-Print Network [OSTI]

The cardiac ventricular muscle cell (myocyte) is a key experimental system for exploring the mechanical properties of the diseased and healthy heart. The myocyte experimental model provides a higher level of physiological ...

Garcia-Webb, Michael G. (Michael Gregory)

2006-01-01T23:59:59.000Z

114

High-throughput methods for characterizing the immune repertoire  

E-Print Network [OSTI]

The adaptive immune system is one of the primary mediators in almost every major human disease, including infections, cancer, autoimmunity, and inflammation-based disorders. It fundamentally functions as a molecular ...

Laserson, Uri

2013-01-01T23:59:59.000Z

115

HIGH-THROUGHPUT COOPERATIVE TRANSMISSIONS USING ADAPTIVE COMPLEX-FIELD NETWORK CODING  

E-Print Network [OSTI]

HIGH-THROUGHPUT COOPERATIVE TRANSMISSIONS USING ADAPTIVE COMPLEX-FIELD NETWORK CODING Guobing Li1 , Alfonso Cano2 , and Georgios B. Giannakis2 1 School of Elect. and Info. Engr., Xi'an Jiaotong University. In this pa- per, a novel cooperation protocol is developed based on adap- tive complex-field wireless network

Pleite, Alfonso Cano

116

ORIGINAL ARTICLE GeoChip 3.0 as a high-throughput tool for analyzing  

E-Print Network [OSTI]

significantly changed with the plant species diversity. As expected, GeoChip 3.0 is a high-throughput powerful Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA and 8 Virtual Institute Keywords: microarray; functional genes; microbial community; plant diversity Introduction Microorganisms

Hazen, Terry

117

ORIGINAL ARTICLE GeoChip 3.0 as a high-throughput tool for analyzing  

E-Print Network [OSTI]

significantly changed with the plant species diversity. As expected, GeoChip 3.0 is a high-throughput powerful Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA and 8 Virtual Institute in microbial ecology Keywords: microarray; functional genes; microbial community; plant diversity Introduction

Weiblen, George D

118

Treatability studies on different refinery wastewater samples using high-throughput microbial electrolysis cells (MECs)  

E-Print Network [OSTI]

, 2005), brewery (Feng et al., 2008), animal (Min et al., 2005) and paper recycling wastewaters (HuangTreatability studies on different refinery wastewater samples using high-throughput microbial, University Park, PA 16802, USA h i g h l i g h t s Refinery wastewaters were tested as fuels in MECs

119

Sample collection for high throughput radiation biodosimetry , H.C. Turner1  

E-Print Network [OSTI]

fingerstick-derived blood samples, either to estimate past radiation dose, or to sort individuals exposed, there will be a major need to assess, within a few days, the radiation doses received by tens or hundreds of thousandsSample collection for high throughput radiation biodosimetry G. Garty1 , H.C. Turner1 , Y. Chen2

Simaan, Nabil

120

WebPSN: a web server for high-throughput investigation of structural communication in biomacromolecules  

Science Journals Connector (OSTI)

......brief-report Applications Note WebPSN: a web server for high-throughput investigation...implemented WebPSN, a freely available web server that allows the user to easily setup...the method was therefore implemented in a web server (WebPSN) that provides the user......

Michele Seeber; Angelo Felline; Francesco Raimondi; Simona Mariani; Francesca Fanelli

2014-11-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

High-throughput imaging of heterogeneous cell organelles with an X-ray laser  

DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

Preprocessed detector images that were used for the paper "High-throughput imaging of heterogeneous cell organelles with an X-ray laser". The CXI file contains the entire recorded data - including both hits and blanks. It also includes down-sampled images and LCLS machine parameters. Additionally, the Cheetah configuration file is attached that was used to create the pre-processed data.

Hantke, Max, F.

122

High-throughput analysis of thin-film stresses using arrays of micromachined cantilever beams  

E-Print Network [OSTI]

High-throughput analysis of thin-film stresses using arrays of micromachined cantilever beams Hyun-throughput residual stress measurements on thin films by means of micromachined cantilever beams and an array of parallel laser beams. In this technique, the film of interest is deposited onto a silicon substrate

123

High-throughput single-molecule fluorescence spectroscopy using parallel detection  

E-Print Network [OSTI]

High-throughput single-molecule fluorescence spectroscopy using parallel detection X. Michalet Solution-based single-molecule fluorescence spectroscopy is a powerful new experimental approach in rare burst-like events corresponding to the transit of a single-molecule. Those events are accumulated

Michalet, Xavier

124

Determination of Monomethylhydrazine with a High-Throughput, All-Fiber Near-Infrared  

E-Print Network [OSTI]

Determination of Monomethylhydrazine with a High-Throughput, All-Fiber Near-Infrared Spectrometer-throughput near-infrared spectrophotometer has been successfully constructed by synergistic use of this integrated and wide spectral band- width in the near-infrared region from 1500 to 1600 nm. This spectral region

Reid, Scott A.

125

High-throughput liquid-absorption preconcentrator sampling methods  

DOE Patents [OSTI]

A system for detecting trace concentrations of an analyte in air includes a preconcentrator for the analyte and an analyte detector. The preconcentrator includes an elongated tubular container comprising a wettable material. The wettable material is continuously wetted with an analyte-sorbing liquid which flows from one part of the container to a lower end. Sampled air flows through the container in contact with the wetted material with a swirling motion which results in efficient transfer of analyte vapors or aerosol particles to the sorbing liquid and preconcentration of traces of analyte in the liquid. The preconcentrated traces of analyte may be either detected within the container or removed therefrom for injection into a separate detection means or for subsequent analysis. 12 figs.

Zaromb, S.

1994-07-12T23:59:59.000Z

126

High-Throughput Mode Liquid Microjunction Surface Sampling Probe  

SciTech Connect (OSTI)

A simple and automated spot sampling operation mode for a liquid microjunction surface sampling probe/electrospray ionization mass spectrometry (LMJ-SSP/ESI-MS) system is reported. Prior manual and automated spot sampling methods with this probe relied on a careful, relatively slow alignment of the probe and surface distance (<20 m spacing) to form the probe-to-surface liquid microjunction critical to successful surface sampling. Moreover, sampling multiple spots required retraction of the surface from the probe and a repeat of this careful probe-to-surface distance alignment at the next sampling position. With the method described here, the probe was not positioned as close to the surface, the exact probeto-surface positioning was found to be less critical (spanning distances from about 100-300 m), and this distance was not altered during the sampling of an entire array of sample spots. With the probe positioned within the appropriate distance from the surface, the liquid microjunction was formed by letting the liquid from the sampling end of the probe extend out from the probe to the surface. This was accomplished by reducing the selfaspiration liquid flow rate of the probe to a value less than the volume flow rate pumped into the probe. When the self-aspiration rate of the probe was subsequently increased, analytes on the surface that dissolved at the liquid microjunction were aspirated back into the probe with the liquid that created the liquid microjunction and electrosprayed. Presented here are the basics of this new sampling mode, as well as data that illustrate the potential analytical capabilities of the device to conduct highthroughput quantitative analysis.

Van Berkel, Gary J [ORNL; Kertesz, Vilmos [ORNL; King, Richard C. [PharmaCadence

2009-01-01T23:59:59.000Z

127

Screening  

Broader source: Energy.gov [DOE]

Screening is typically performed by an outside party or an independent renewable energy expert or team. It is a review of the possible technology options that identifies dead-ends and further...

128

A Whole-Cell Phenotypic Screening Platform for Identifying Methylerythritol Phosphate Pathway-Selective Inhibitors as Novel Antibacterial Agents  

Science Journals Connector (OSTI)

...IPTG. For screening chemical libraries, the platform is capable of evaluating...is activated. The platform is a simple, robust...We developed the platform using 96-well plates...high-throughput screening of chemical collections. Both...

Charles A. Testa; L. Jeffrey Johnson

2012-07-09T23:59:59.000Z

129

High-throughput data mined prediction of inorganic compounds and computational discovery of new lithium-ion battery cathode materials  

E-Print Network [OSTI]

The ability to computationally predict the properties of new materials, even prior to their synthesis, has been made possible due to the current accuracy of modern ab initio techniques. In some cases, high-throughput ...

Hautier, Geoffroy (Geoffroy T. F.)

2011-01-01T23:59:59.000Z

130

Advances in high-throughput speed, low-latency communication for embedded instrumentation ( 7th Annual SFAF Meeting, 2012)  

SciTech Connect (OSTI)

Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Jordan, Scott [Physik Instrumente] [Physik Instrumente

2012-06-01T23:59:59.000Z

131

Advances in high-throughput speed, low-latency communication for embedded instrumentation ( 7th Annual SFAF Meeting, 2012)  

ScienceCinema (OSTI)

Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Jordan, Scott [Physik Instrumente

2013-02-11T23:59:59.000Z

132

High Throughput Plasmid Sequencing with Illumina and CLC Bio (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)  

ScienceCinema (OSTI)

Ajay Athavale (Monsanto) presents "High Throughput Plasmid Sequencing with Illumina and CLC Bio" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

Athavale, Ajay [Monsanto

2013-01-25T23:59:59.000Z

133

Screening system and method of using same  

SciTech Connect (OSTI)

An integrated apparatus and method for screening an object for a target material is provided. The integrated apparatus comprises a housing and an integrated screener. The housing is positionable adjacent the object, and has a channel therethrough. The integrated screener is positionable in the housing, and comprises a fan, at least one filter, a heater and an analyzer. The fan is for drawing air carrying particles and vapor through the channel of the housing. The filter(s) is/are positionable in the channel of the housing for passage of the air therethrough. The filter(s) comprise(s) at least one metal foam having a plurality of pores therein for collecting and adsorbing a sample from the particles and vapor passing therethrough. The heater is for applying heat to the at least one metal foam whereby the collected sample is desorbed from the metal foam. The analyzer detects the target material from the desorbed sample.

Jones, David A; Gresham, Christopher A; Basiliere, Marc L; Spates, James J; Rodacy, Philip J

2014-04-15T23:59:59.000Z

134

Nano-chemo-mechanical sensor array platform for high-throughput chemical analysis  

Science Journals Connector (OSTI)

We have developed a 2-D multiplexed cantilever array platform for high-throughput nanomechanical chemical sensing and analysis. After coating the cantilevers with alkane thiols having different functional end groups, we have performed vapor phase chemical sensing experiments with toluene and water vapor as targets. To overcome non-uniform responses caused by fabrication and imaging issues, the chemical response of each cantilever is self-calibrated using the thermal response of each cantilever. From these experiments, we could observe chemically induced nanoscale motion of cantilevers for various humidity or vapor concentration levels, and response differentiation with different functional end groups of thiols.

Si-Hyung Shawn Lim; Digvijay Raorane; Srinath Satyanarayana; Arunava Majumdar

2006-01-01T23:59:59.000Z

135

SMART SCREENING SYSTEM (S3) IN TACONITE PROCESSING  

SciTech Connect (OSTI)

The conventional vibrating machines used in processing plants have had undesirable high noise and vibration levels. They also have had unsatisfactorily low screening efficiency, high energy consumption, high maintenance cost, low productivity, and poor worker safety. These conventional vibrating machines have been used in most every processing plant. Most of the current material separation technology uses heavy and inefficient electric motors with an unbalance rotating mass to generate the shaking. In addition to being excessively noisy, inefficient, high-maintenance, these vibrating machines are often the bottleneck in the entire process. Furthermore, these motors along with the vibrating machines and supporting structure shake other machines and structure in the vicinity. The latter increases maintenance costs while reducing worker health and safety. The conventional vibrating fine screens at taconite processing plants have had the same problems as those listed above. This has resulted in lower screening efficiency, higher energy and maintenance cost, and lower productivity and workers safety concerns. The focus of this work is on the design of a high performance screening machine suitable for taconite processing plants. SmartScreens{trademark} technology uses miniaturized motors, based on smart materials, to generate the shaking. The underlying technologies are Energy Flow Control{trademark} and Vibration Control by Confinement{trademark}. These concepts are used to direct energy flow and confine energy efficiently and effectively to the screen function. The SmartScreens{trademark} technology addresses problems related to noise and vibration, screening efficiency, productivity, and maintenance cost and worker safety. Successful development of SmartScreens{trademark} technology will bring drastic changes to the screening and physical separation industry. The conceptual designs for key components of the SmartScreens{trademark} have been developed. These key components include: smart motors and resonators. It is shown that the smart motors have a good life and performance. The resonators are utilized to amplify motion generated by smart motors. Resonator designs are selected based on the final system requirement and vibration characteristics. In addition, a tabletop demo unit was developed and demonstrated during a conference in 2003. This demo is reviewed in this report. The concept has shown promise and the program is on schedule.

Daryoush Allaei; Asim Syed Mohammed

2004-04-01T23:59:59.000Z

136

A high throughput platform for understanding the influence of excipients on physical and chemical stability  

Science Journals Connector (OSTI)

The present study puts forward a miniaturized high-throughput platform to understand influence of excipient selection and processing on the stability of a given drug compound. Four model drugs (sodium naproxen, theophylline, amlodipine besylate and nitrofurantoin) and ten different excipients were selected. Binary physical mixtures of drug and excipient were transferred to a 96-well plate followed by addition of water to simulate aqueous granulation environment. The plate was subjected for XRPD measurements followed by drying and subsequent XRPD and HPLC measurements of the dried samples. Excipients with different water sorbing potential were found to influence distinctly on the phase transformation behaviour of each drug. Moreover, the amount of water addition was also a critical factor affecting phase transformation behaviour. HPLC analysis revealed one of the drug:excipient pairs with a tendency for chemical degradation. The proposed high-throughput platform can be used during early drug development to simulate typical processing induced stress in a small scale and to understand possible phase transformation behaviour and influence of excipients on this.

Dhara Raijada; Claus Cornett; Jukka Rantanen

2013-01-01T23:59:59.000Z

137

Smart Screening System (S3) In Taconite Processing  

SciTech Connect (OSTI)

The conventional vibrating machines used in processing plants have had undesirable high noise and vibration levels. They also have had unsatisfactorily low screening efficiency, high energy consumption, high maintenance cost, low productivity, and poor worker safety. These conventional vibrating machines have been used in most every processing plant. Most of the current material separation technology uses heavy and inefficient electric motors with an unbalance rotating mass to generate the shaking. In addition to being excessively noisy, inefficient, and high-maintenance, these vibrating machines are often the bottleneck in the entire process. Furthermore, these motors, along with the vibrating machines and supporting structure, shake other machines and structures in the vicinity. The latter increases maintenance costs while reducing worker health and safety. The conventional vibrating fine screens at taconite processing plants have had the same problems as those listed above. This has resulted in lower screening efficiency, higher energy and maintenance cost, and lower productivity and workers safety concerns. The focus of this work is on the design of a high performance screening machine suitable for taconite processing plants. SmartScreens{trademark} technology uses miniaturized motors, based on smart materials, to generate the shaking. The underlying technologies are Energy Flow Control{trademark} and Vibration Control by Confinement{trademark}. These concepts are used to direct energy flow and confine energy efficiently and effectively to the screen function. The SmartScreens{trademark} technology addresses problems related to noise and vibration, screening efficiency, productivity, and maintenance cost and worker safety. Successful development of SmartScreens{trademark} technology will bring drastic changes to the screening and physical separation industry. The final designs for key components of the SmartScreens{trademark} have been developed. The key components include smart motor and associated electronics, resonators, and supporting structural elements. It is shown that the smart motors have an acceptable life and performance. Resonator (or motion amplifier) designs are selected based on the final system requirement and vibration characteristics. All the components for a fully functional prototype are fabricated. The system is assembled and tested under laboratory and field conditions. The lab results are promising and the field test resulted in system performance drop due to plant structure not able to provide the required stiffness. The PZT-based Smart Motors performed better than expected. None of the Smart Motors failed during testing and the results were very encouraging. The development program is on schedule. Supporting structure was modified to improve system rigidity and integrity to help improve overall system performance. The improved supporting structure was fabricated and tested in the lab and in field. Results showed a significant improvement in reducing undesirable supporting structure vibration, better system performance and ease of installation. We plan to work on system installation sensitivity to relax plant structure foundation requirement. This would be necessary for the PZT-based system to perform better and not loose energy into the plant structure.

Daryoush Allaei; Asim Syed Mohammed; David Tarnowski

2004-09-01T23:59:59.000Z

138

Image-Based Chemical Screening Identifies Drug Efflux Inhibitors in Lung Cancer Cells  

Science Journals Connector (OSTI)

...ICR's basic science and have invested heavily in high-throughput screening robotics, crystallography, and high-performance computing for integrative genomics and chemobiology. Crucially, we're all under one roof, co-located with the...

Xiaofeng Xia; Jian Yang; Fuhai Li; Ying Li; Xiaobo Zhou; Yue Dai; Stephen T.C. Wong

2010-10-01T23:59:59.000Z

139

High-throughput manufacturing of thin-film CdTe photovoltaic modules  

Science Journals Connector (OSTI)

The main obstacle to the wide spread use of photovoltaics as a major source of renewable energy has been cost. The key to lowering the cost of photovoltaic generated energy to the levels of conventional sources of energy lays in the development of low cost high throughput manufacturing processes. Solar Cells Inc. (SCI) believes this can be achieved for CdTe based modules by integrating its PV fabrication processes with a modern glass plant. That is sand in finished module out. It is also necessary to have a stable end product in order to gain wide acceptance. SCI has been working at producing large-area CdS/CdTe photovoltaic (PV) modules and the processes developed at SCI can be scaled to achieve high production levels at cost-effective rates.

Alan McMaster; Steve Johnson

1999-01-01T23:59:59.000Z

140

Nanoelectrospray ion generation for high-throughput mass spectrometry using a micromachined ultrasonic ejector array  

SciTech Connect (OSTI)

Ultrasonic electrospray ionization (ESI) for high-throughput mass spectrometry is demonstrated using a silicon micromachined microarray. The device uses a micromachined ultrasonic atomizer operating in the 900 kHz-2.5 MHz range for droplet generation and a metal electrode in the fluid cavity for ionization. Since the atomization and ionization processes are separated, the ultrasonic ESI source shows the potential for operation at low voltages with a wide range of solvents in contrast with conventional capillary ESI technology. This is demonstrated using the ultrasonic ESI microarray to obtain the mass spectrum of a 10 {mu}M reserpine sample on a time of flight mass spectrometer with 197:1 signal-to-noise ratio at an ionization potential of 200 V.

Aderogba, S.; Meacham, J.M.; Degertekin, F.L.; Fedorov, A.G.; Fernandez, F.M. [G.W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States)

2005-05-16T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

High-throughput Accurate-wavelength Lens-based Visible Spectrometera  

SciTech Connect (OSTI)

A scanning visible spectrometer has been prototyped to complement fixed-wavelength transmission grating spectrometers for charge exchange recombination spectroscopy. Fast f/1.8 200 mm commercial lenses are used with a large 2160 mm-1 grating for high throughput. A stepping-motor controlled sine drive positions the grating, which is mounted on a precision rotary table. A high-resolution optical encoder on the grating stage allows the grating angle to be measured with an absolute accuracy of 0.075 arcsec, corresponding to a wavelength error ? 0.005 . At this precision, changes in grating groove density due to thermal expansion and variations in the refractive index of air are important. An automated calibration procedure determines all relevant spectrometer parameters to high accuracy. Changes in bulk grating temperature, atmospheric temperature and pressure are monitored between the time of calibration and the time of measurement to insure a persistent wavelength calibration

Ronald E. Belll and Filippo Scotti

2010-06-04T23:59:59.000Z

142

Bench-Top Engine System for Fast Screening of Alternative Fuels...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

System for Fast Screening of Alternative Fuels and Fuel Additives A bench-top engine testing system was used to fast screen the efficiency of fuel additives or fuel blends on NOx...

143

A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor  

SciTech Connect (OSTI)

The telomere-associated protein tankyrase 1 is a poly(ADP-ribose) polymerase and is considered to be a promising target for cancer therapy, especially for BRCA-associated cancers. However, an efficient assay system for inhibitor screening has not been established, mainly due to the difficulty of efficient preparation of the enzyme and its substrate. Here, we report a cell-based assay system for detecting inhibitory activity against tankyrase 1. We found that overexpression of the human tankyrase 1 gene causes a growth defect in the fission yeast Schizosaccharomyces pombe. Chemicals that restore the growth defect phenotype can be identified as potential tankyrase 1 inhibitors. We performed a high-throughput screen using this system, and identified flavone as a compound that restores the growth of yeast cells overexpressing tankyrase 1. Indeed, flavone inhibited poly(ADP-ribosyl)ation of proteins caused by overexpression of tankyrase 1 in yeast cells. This system allows rapid identification of inhibitory activity against tankyrase 1 and is amenable to high-throughput screening using robotics.

Yashiroda, Yoko, E-mail: ytyy@riken.jp [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan)] [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Okamoto, Reika [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan) [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Japan Biological Informatics Consortium (JBIC), Koto-ku, Tokyo 135-8073 (Japan); Hatsugai, Kaori [Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Koto-ku, Tokyo 135-8550 (Japan) [Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Koto-ku, Tokyo 135-8550 (Japan); Division of Chemotherapy, Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo 105-8512 (Japan); Takemoto, Yasushi [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan)] [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Goshima, Naoki [National Institute of Advanced Industrial Science and Technology, Koto-ku, Tokyo 135-0064 (Japan)] [National Institute of Advanced Industrial Science and Technology, Koto-ku, Tokyo 135-0064 (Japan); Saito, Tamio [Chemical Biology Core Facility/Antibiotics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan)] [Chemical Biology Core Facility/Antibiotics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Hamamoto, Makiko [Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa 214-8571 (Japan)] [Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa 214-8571 (Japan); Sugimoto, Yoshikazu [Division of Chemotherapy, Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo 105-8512 (Japan)] [Division of Chemotherapy, Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo 105-8512 (Japan); Osada, Hiroyuki [Chemical Biology Core Facility/Antibiotics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan)] [Chemical Biology Core Facility/Antibiotics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Seimiya, Hiroyuki [Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Koto-ku, Tokyo 135-8550 (Japan)] [Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Koto-ku, Tokyo 135-8550 (Japan); Yoshida, Minoru [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan) [Chemical Genomics Research Group/Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); CREST Research Project, Japan Science and Technology Corporation, Saitama 332-0012 (Japan)

2010-04-09T23:59:59.000Z

144

PIPA: A High-Throughput Pipeline for Protein Function Annotation Chenggang Yu, Valmik Desai, Nela Zavaljevski, and Jaques Reifman  

E-Print Network [OSTI]

PIPA: A High-Throughput Pipeline for Protein Function Annotation Chenggang Yu, Valmik Desai, Nela of multisource predictions. We developed Pipeline for Protein Annotation (PIPA), a genome-wide protein function annotation pipeline that runs in a high-performance computing environment. PIPA integrates different tools

145

PIPELINED PARALLEL ARCHITECTURE FOR HIGH THROUGHPUT MAP DETECTORS Ruwan Ratnayake, Gu-Yeon Wei and Aleksandar Kavcic  

E-Print Network [OSTI]

PIPELINED PARALLEL ARCHITECTURE FOR HIGH THROUGHPUT MAP DETECTORS Ruwan Ratnayake, Gu-Yeon Wei performance close to the channel capacity limits. Deep pipelined architecture for the forward only method, where as FB-BCJR only allow sequential state metric computations. Parallelism facilitates pipelining, re

Kavcic, Aleksandar

146

A High-Throughput Study of PtNiZr Catalysts for Application in PEM Fuel Cells  

SciTech Connect (OSTI)

The effects of adding Zr to PtNi oxygen reduction reaction (ORR) electrocatalyst alloys were examined in a study aimed at probing the possibility of creating catalysts with enhanced resistance to corrosion in a PEM fuel cell environment. Samples consisting of pure Pt or PtNiZr alloys with a range of compositions (not exceeding 11 at.% Zr) were fabricated using co-sputter deposition. A high-throughput fabrication approach was used wherein 18 distinct thin film catalyst alloy samples with varying compositions were deposited onto a large-area substrate with individual Au current collector structures. A multi-channel pseudo-potentiostat allowed for the simultaneous quantitative study of catalytic activity for all 18 electrodes in a single test bath, a first for the study of ORR electrocatalysts. A properly stirred oxygenated 1 M H{sub 2}SO{sub 4} electrolyte solution was used to provide each electrode with a steady-state flow of reactants during electrochemical evaluation. The onset potentials, absolute current density values, and Tafel analysis data obtained using this technique were compared with literature reports. The analyses showed that most PtNiZr alloys tested offered improvements over pure Pt, however those surfaces with a high mole fraction (>4 at.%) of Zr exhibited reduced activity that was roughly inversely correlated to the amount of Zr present. Film composition, morphology, and crystallographic properties were examined using X-ray energy dispersive spectroscopy (XEDS), X-ray photoelectron spectroscopy (XPS), SEM, and synchrotron X-ray diffraction. These data were then correlated with electrochemical data to elucidate the relationships between composition, structure, and relative performance for this ternary system.

Whitacre, J.F.; Valdez, T.I.; Narayanan, S.R.

2009-05-26T23:59:59.000Z

147

PHYSICAL REVIEW B 90, 174107 (2014) High-throughput computational screening of thermal conductivity, Debye temperature, and  

E-Print Network [OSTI]

for the past few decades [6]. Low thermal conductivity materials constitute the basis of a new generation such as the Debye temperature and the thermal conductivity of materials. We demonstrate that the AGL method, which ranking of the thermal conductivity for several different classes of semiconductor materials

Curtarolo, Stefano

148

Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library  

Science Journals Connector (OSTI)

...copy of the compound library and retested in triplicate...is a critical global public health priority. Leishmania...small-molecule chemical library of 80,000 drug-like...design of the chemical library being that lead-like...better cover diversity space. We have commented in...

Kurt Lackovic; John P. Parisot; Nerida Sleebs; Jonathan B. Baell; Laurent Debien; Keith G. Watson; Joan M. Curtis; Emanuela Handman; Ian P. Street; Lukasz Kedzierski

2010-02-16T23:59:59.000Z

149

PHYSICAL REVIEW B 84, 014103 (2011) Screening for high-performance piezoelectrics using high-throughput density functional theory  

E-Print Network [OSTI]

-throughput density functional theory Rickard Armiento,1 Boris Kozinsky,2 Marco Fornari,3 and Gerbrand Ceder1 1-scale density functional theory (DFT) investigation of the ABO3 chemical space in the perovskite crystal-throughput density functional theory19,20 calculations. The last decades have seen a rapid increase of computational

Ceder, Gerbrand

150

High-Throughput Screen Identifies Novel Inhibitors of Cancer Biomarker ?-Methylacyl Coenzyme A Racemase (AMACR/P504S)  

Science Journals Connector (OSTI)

...opposite stereoisomer after diastereomeric separation using either gas chromatography (GC) or high-performance liquid chromatography...Biochim Biophys Acta 1997;1347:62-8. 26. Carnell AJ , Hale I, Denis S, Wanders RJ, Isaacs WB, Wilson BA, et alDesign...

Brice A.P. Wilson; Haofan Wang; Benjamin A. Nacev; Ronnie C. Mease; Jun O. Liu; Martin G. Pomper; and William B. Isaacs

2011-05-01T23:59:59.000Z

151

The Development of Microfabricated Microbial Fuel Cell Array as a High Throughput Screening Platform for Electrochemically Active Microbes  

E-Print Network [OSTI]

: Illustration of the 24-well air-cathode MFC array. (1) Anode layer, (2) anode chamber layer, (3) air-cathode layer (PEM/carbon cloth assembly), (4) air-cathode interface. B: Air-cathode interface microfabrication steps. (1) Au/Ti deposited PMMA substrate...

Hou, Huijie

2012-02-14T23:59:59.000Z

152

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus  

E-Print Network [OSTI]

was assessed using Cell Titer Glo.factors greater than 0.8 (0.82 0.02), however, the CV Figure 3 Dose response of ribavirin. HEp-2 cells were plated in 384-well black tissue culture plates at 2,000 cells per well. Ribavirin or carrier control (DMSO) were... The positive control drug for this assay, ribavirin (MP Biomedicals, Solon, OH) was solubilized in DMSO, diluted and added to the assay plates as described for Chung et al. Virology Journal 2013, 10:19 Page 10 of 12 http://www.virologyj.com/content/10/1/19test...

Chung, Dong-Hoon; Moore, Blake P.; Matharu, Daljit S.; Golden, Jennifer E.; Maddox, Clinton; Rasmussen, Lynn; Sosa, Melinda I.; Ananthan, Subramaniam; White, E. Lucile; Jia, Fuli; Jonsson, Colleen B.; Severson, William E.

2013-01-10T23:59:59.000Z

153

Development of High-Throughput Screens to Target SAM-I Riboswitches (2014 DOE JGI Genomics of Energy & Environment Meeting)  

SciTech Connect (OSTI)

Scott Hickey of the University of California Berkeley speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Hickey, Scott [UC Berkely

2014-03-19T23:59:59.000Z

154

Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway  

E-Print Network [OSTI]

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that induces a battery of cytoprotective genes involved in antioxidant defense through binding to Antioxidant Response Elements (ARE) located in the promoter regions...

Wu, Kai Connie; McDonald, Peter R.; Liu, Jie Jerry; Chaguturu, Rathnam; Klaassen, Curtis D.

2012-10-08T23:59:59.000Z

155

A Cell-Based High-Throughput Screen for Novel Chemical Inducers of Fetal Hemoglobin for Treatment of Hemoglobinopathies  

E-Print Network [OSTI]

treatment for sickle cell disease (SCD) is increased fetal hemoglobin (HbF). Identification of a drug specific for inducing c-globin expression in pediatric and adult patients, with minimal off-target effects, continues to be an elusive goal. One hurdle has..., Kansas, United States of America c Current address: SRI International, Harrisonburg, Virginia, United States of America Introduction Sickle cell disease (SCD) is the most common monogenetic disease diagnosed in the United States, affecting approximately...

Peterson, Kenneth R.; Costa, Flá via C.; Fedosyuk, Halyna; Neades, Renee Y.; Chazelle, Allen M.; Zelenchuk, Lesya; Fonteles, Andrea H.; Dalal, Parmita; Roy, Anuradha; Chaguturu, Rathnam; Li, Biaoru; Pace, Betty S.

2014-09-16T23:59:59.000Z

156

High-Throughput Screening of Mg-Functionalized Metal-Organic Frameworks for Hydrogen Storage near Room Temperature  

E-Print Network [OSTI]

The hydrogen storage capabilities of 18,383 porous crystalline structures possessing various degrees of Mg functionalization and diverse physical properties were assessed through combined grand canonical Monte Carlo (GCMC) and quantum mechanical...

Coln, Yamil J.; Fairen-Jimenez, David; Wilmer, Christopher E.; Snurr, Randall Q.

2014-01-01T23:59:59.000Z

157

High Throughput Software for Powder Diffraction and its Application to Heterogeneous Catalysis  

E-Print Network [OSTI]

In this thesis we investigate high throughput computational methods for processing large quantities of data collected from synchrotrons and their application to spectral analysis of powder diffraction data. We also present the main product of this PhD programme, specifically a software called 'EasyDD' developed by the author. This software was created to meet the increasing demand on data processing and analysis capabilities as required by modern detectors which produce huge quantities of data. Modern detectors coupled with the high intensity X-ray sources available at synchrotrons have led to the situation where datasets can be collected in ever shorter time scales and in ever larger numbers. Such large volumes of datasets pose a data processing bottleneck which augments with current and future instrument development. EasyDD has achieved its objectives and made significant contributions to scientific research. It can also be used as a model for more mature attempts in the future. EasyDD is currently in use by a number of researchers in a number of academic and research institutions to process high-energy diffraction data. These include data collected by different techniques such as Energy Dispersive Diffraction, Angle Dispersive Diffraction and Computer Aided Tomography. EasyDD has already been used in a number of published studies, and is currently in use by the High Energy X-Ray Imaging Technology project. The software was also used by the author to process and analyse datasets collected from synchrotron radiation facilities. In this regard, the thesis presents novel scientific research involving the use of EasyDD to handle large diffraction datasets in the study of alumina-supported metal oxide catalyst bodies. These data were collected using Tomographic Energy Dispersive Diffraction Imaging and Computer Aided Tomography techniques.

Taha Sochi

2010-12-20T23:59:59.000Z

158

Development of a multiplexed microbioreactor system for high-throughput bioprocessing  

E-Print Network [OSTI]

. However, this is a challenge with current bioreactor technology. The high cost and labor required and fluidic connectors, their sterilization, and disassembly and cleaning. While some fermentation parameters), for example, operates six reactors in parallel, and the ``Fedbatch-Pro'' (DASGIP AG, Germany) includes up

Sinskey, Anthony J.

159

Application of High Throughput Pretreatment and Co-Hydrolysis System to Thermochemical  

E-Print Network [OSTI]

and growing energy demands, as well as to reduce the environmental impacts associated with production to biofuels and other biomaterials by a number of routes (Himmel et al., 2007). To produce biofuels. Wyman Contract grant sponsor: Office of Biological and Environmental Research Contract grant sponsor

California at Riverside, University of

160

Integrated crystal mounting and alignment system for high-throughput biological crystallography  

DOE Patents [OSTI]

A method and apparatus for the transportation, remote and unattended mounting, and visual alignment and monitoring of protein crystals for synchrotron generated x-ray diffraction analysis. The protein samples are maintained at liquid nitrogen temperatures at all times: during shipment, before mounting, mounting, alignment, data acquisition and following removal. The samples must additionally be stably aligned to within a few microns at a point in space. The ability to accurately perform these tasks remotely and automatically leads to a significant increase in sample throughput and reliability for high-volume protein characterization efforts. Since the protein samples are placed in a shipping-compatible layered stack of sample cassettes each holding many samples, a large number of samples can be shipped in a single cryogenic shipping container.

Nordmeyer, Robert A. (San Leandro, CA); Snell, Gyorgy P. (Richmond, CA); Cornell, Earl W. (Antioch, CA); Kolbe, William F. (Moraga, CA); Yegian, Derek T. (Oakland, CA); Earnest, Thomas N. (Berkeley, CA); Jaklevich, Joseph M. (Lafayette, CA); Cork, Carl W. (Walnut Creek, CA); Santarsiero, Bernard D. (Chicago, IL); Stevens, Raymond C. (La Jolla, CA)

2007-09-25T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Application of High Throughput Pretreatment and Co-Hydrolysis System to Thermochemical  

E-Print Network [OSTI]

and enzymatic hydrolysis conditions. Although hydrothermal pretreatment is currently being employed in most high were compared to results from hydrothermal pretreatments, providing new insights in understanding their recalcitrance and consolidating processing of enzymes and microorganisms to overcome biomass recalci- trance

California at Riverside, University of

162

Bench-Top Engine System for Fast Screening of Alternative Fuels and Fuel Additives  

Broader source: Energy.gov [DOE]

A bench-top engine testing system was used to fast screen the efficiency of fuel additives or fuel blends on NOx reduction

163

New Challenges of the Computation of Multiple Sequence Alignments in the High-Throughput Era (2010 JGI/ANL HPC Workshop)  

ScienceCinema (OSTI)

Cedric Notredame from the Centre for Genomic Regulation gives a presentation on "New Challenges of the Computation of Multiple Sequence Alignments in the High-Throughput Era" at the JGI/Argonne HPC Workshop on January 26, 2010.

Notredame, Cedric [Centre for Genomic Regulation

2011-06-08T23:59:59.000Z

164

Trial of a Bacterial Screening System for Rapid Detection of Mutagens and Carcinogens  

Science Journals Connector (OSTI)

...of a Bacterial Screening System for Rapid Detection of Mutagens and Carcinogens...Missouri 63103 A bacterial test system for detection of mutagens and carcinogens...SUMMARY A bacterial test system for detection of mutagens and carcinogens...

Daniel S. Longnecker; Thomas J. Curphey; Susan T. James; Douglas S. Daniel; and Nicholas J. Jacobs

1974-07-01T23:59:59.000Z

165

Screening for Colorectal Cancer in a Safety-Net Health Care System: Access to Care Is Critical and Has Implications for Screening Policy  

Science Journals Connector (OSTI)

...Cancer in a Safety-Net Health Care System: Access to Care Is Critical and Has Implications for Screening Policy...cancer in a safety-net health care system: access to care is critical and has implications for screening policy...sparse for safety-net health systems. A retrospective...

Samir Gupta; Liyue Tong; James E. Allison; Elizabeth Carter; Mark Koch; Don C. Rockey; Paula Anderson; Chul Ahn; Keith Argenbright; and Celette Sugg Skinner

2009-09-01T23:59:59.000Z

166

Scalable Parallel Screening of Catalyst Activity at the Single-Particle Level and Subdiffraction Resolution  

E-Print Network [OSTI]

Scalable Parallel Screening of Catalyst Activity at the Single-Particle Level and Subdiffraction ABSTRACT: High-throughput and quantitative screening of catalyst activity is crucial for guiding the work cycles of catalyst improvements and optimizations. For nanoparticle catalysts, their inherent

Chen, Peng

167

High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization  

Science Journals Connector (OSTI)

Abstract Microfluidics has recently emerged as a new method of manufacturing liposomes, which allows for reproducible mixing in miliseconds on the nanoliter scale. Here we investigate microfluidics-based manufacturing of liposomes. The aim of these studies was to assess the parameters in a microfluidic process by varying the total flow rate (TFR) and the flow rate ratio (FRR) of the solvent and aqueous phases. Design of experiment and multivariate data analysis were used for increased process understanding and development of predictive and correlative models. High FRR lead to the bottom-up synthesis of liposomes, with a strong correlation with vesicle size, demonstrating the ability to in-process control liposomes size; the resulting liposome size correlated with the FRR in the microfluidics process, with liposomes of 50nm being reproducibly manufactured. Furthermore, we demonstrate the potential of a high throughput manufacturing of liposomes using microfluidics with a four-fold increase in the volumetric flow rate, maintaining liposome characteristics. The efficacy of these liposomes was demonstrated in transfection studies and was modelled using predictive modeling. Mathematical modelling identified FRR as the key variable in the microfluidic process, with the highest impact on liposome size, polydispersity and transfection efficiency. This study demonstrates microfluidics as a robust and high-throughput method for the scalable and highly reproducible manufacture of size-controlled liposomes. Furthermore, the application of statistically based process control increases understanding and allows for the generation of a design-space for controlled particle characteristics.

Elisabeth Kastner; Randip Kaur; Deborah Lowry; Behfar Moghaddam; Alexander Wilkinson; Yvonne Perrie

2014-01-01T23:59:59.000Z

168

Synthesis and Screening of Thin Films in the CeCl3-CeBr3 System...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Screening of Thin Films in the CeCl3-CeBr3 System for Scintillator Applications. Synthesis and Screening of Thin Films in the CeCl3-CeBr3 System for Scintillator Applications....

169

High-throughput identification of off-targets for the mechanistic study of severe adverse drug reactions induced by analgesics  

SciTech Connect (OSTI)

Drugs may induce adverse drug reactions (ADRs) when they unexpectedly bind to proteins other than their therapeutic targets. Identification of these undesired protein binding partners, called off-targets, can facilitate toxicity assessment in the early stages of drug development. In this study, a computational framework was introduced for the exploration of idiosyncratic mechanisms underlying analgesic-induced severe adverse drug reactions (SADRs). The putative analgesic-target interactions were predicted by performing reverse docking of analgesics or their active metabolites against human/mammal protein structures in a high-throughput manner. Subsequently, bioinformatics analyses were undertaken to identify ADR-associated proteins (ADRAPs) and pathways. Using the pathways and ADRAPs that this analysis identified, the mechanisms of SADRs such as cardiac disorders were explored. For instance, 53 putative ADRAPs and 24 pathways were linked with cardiac disorders, of which 10 ADRAPs were confirmed by previous experiments. Moreover, it was inferred that pathways such as base excision repair, glycolysis/glyconeogenesis, ErbB signaling, calcium signaling, and phosphatidyl inositol signaling likely play pivotal roles in drug-induced cardiac disorders. In conclusion, our framework offers an opportunity to globally understand SADRs at the molecular level, which has been difficult to realize through experiments. It also provides some valuable clues for drug repurposing. - Highlights: A novel computational framework was developed for mechanistic study of SADRs. Off-targets of drugs were identified in large scale and in a high-throughput manner. SADRs like cardiac disorders were systematically explored in molecular networks. A number of ADR-associated proteins were identified.

Pan, Jian-Bo [Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005 (China); Ji, Nan; Pan, Wen; Hong, Ru [State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102 (China); Wang, Hao [Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005 (China); Ji, Zhi-Liang, E-mail: appo@xmu.edu.cn [State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102 (China); Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005 (China)

2014-01-01T23:59:59.000Z

170

High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury  

SciTech Connect (OSTI)

Many environmental chemicals and drugs negatively affect human health through deleterious effects on mitochondrial function. Currently there is no chemical library of mitochondrial toxicants, and no reliable methods for predicting mitochondrial toxicity. We hypothesized that discrete toxicophores defined by distinct chemical entities can identify previously unidentified mitochondrial toxicants. We used a respirometric assay to screen 1760 compounds (5 ?M) from the LOPAC and ChemBridge DIVERSet libraries. Thirty-one of the assayed compounds decreased uncoupled respiration, a stress test for mitochondrial dysfunction, prior to a decrease in cell viability and reduced the oxygen consumption rate in isolated mitochondria. The mitochondrial toxicants were grouped by chemical similarity and two clusters containing four compounds each were identified. Cheminformatic analysis of one of the clusters identified previously uncharacterized mitochondrial toxicants from the ChemBridge DIVERSet. This approach will enable the identification of mitochondrial toxicants and advance the prediction of mitochondrial toxicity for both drug discovery and risk assessment. - Highlights: Respirometric assay conducted in RPTC to create mitochondrial toxicant database. Chemically similar mitochondrial toxicants aligned as mitochondrial toxicophores Mitochondrial toxicophore identifies five novel mitochondrial toxicants.

Wills, Lauren P. [MitoHealth Inc., Charleston, SC 29403 (United States); Beeson, Gyda C.; Trager, Richard E.; Lindsey, Christopher C. [Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425 (United States); Beeson, Craig C. [MitoHealth Inc., Charleston, SC 29403 (United States); Peterson, Yuri K. [Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425 (United States); Schnellmann, Rick G., E-mail: schnell@musc.edu [Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425 (United States); Ralph H. Johnson VA Medical Center, Charleston, SC 29401 (United States)

2013-10-15T23:59:59.000Z

171

Pathway-centric approaches to the analysis of high-throughput genomics data.  

E-Print Network [OSTI]

??In the last decade, molecular biology has expanded from a reductionist view to a systems-wide view that tries to unravel the complex interactions of cellular (more)

Hnzelmann, Sonja, 1981-

2012-01-01T23:59:59.000Z

172

A microfluidics approach towards high-throughput pathogen removal from blood using margination  

E-Print Network [OSTI]

Sepsis is an adverse systemic inflammatory response caused by microbial infection in blood. This paper reports a simple microfluidic approach for intrinsic, non-specific removal of both microbes and inflammatory cellular ...

Hou, Han Wei

173

Database Requirements for Workflow Management in a HighThroughput Genome Laboratory 1  

E-Print Network [OSTI]

Database Requirements for Workflow Management in a High­Throughput Genome Laboratory 1 Anthony J and operationally efficient. A key component of this software is a database management system (DBMS) for controlling constitutes an audit trail, or event history, and has much the same function as a laboratory notebook

Bonner, Anthony

174

A WiMAX/LTE Compliant FPGA Implementation of a High-Throughput Low-Complexity 4x4 64-QAM Soft MIMO Receiver  

E-Print Network [OSTI]

of antennas and constellation order. Therefore, it is suitable for LTE-Advanced and IEEE 802.16m broadband must be scalable as the number of antennas and the constellation order increase in order to meet high, an appropriate VLSI archi- tecture is required to yield high-throughput, energy- efficient implementation

Gulak, P. Glenn

175

Asynchronous Progression through the Lytic Cascade and Variations in Intracellular Viral Loads Revealed by High-Throughput Single-Cell Analysis of Kaposi's Sarcoma-Associated Herpesvirus Infection  

Science Journals Connector (OSTI)

...microscopy with the statistical power of high-throughput traditional...cytometry. We collected data on infected HeLa cells...assess intracellular viral load in individual cells...12, 20, 21). Our data indicate that the automated...correlates with the viral load in individual cells...

Laura A. Adang; Christopher H. Parsons; Dean H. Kedes

2006-10-15T23:59:59.000Z

176

Exploring Flexible Strategies in Engineering Systems Using Screening Models Applications to Offshore Petroleum Projects  

E-Print Network [OSTI]

to Offshore Petroleum Projects by Jijun Lin B.E., Mechanical Engineering, Beijing University of Aeronautics Flexible Strategies in Engineering Systems Using Screening Models Applications to Offshore Petroleum, such as offshore petroleum exploration and production systems, generally require a significant amount of capital

de Weck, Olivier L.

177

On-the-fly machine-learning for high-throughput experiments: search for rare-earth-free permanent magnets  

SciTech Connect (OSTI)

Advanced materials characterization techniques with ever-growing data acquisition speed and storage capabilities represent a challenge in modern materials science, and new procedures to quickly assess and analyze the data are needed. Machine learning approaches are effective in reducing the complexity of data and rapidly homing in on the underlying trend in multi-dimensional data. Here, we show that by employing an algorithm called the mean shift theory to a large amount of diffraction data in high-throughput experimentation, one can streamline the process of delineating the structural evolution across compositional variations mapped on combinatorial libraries with minimal computational cost. Data collected at a synchrotron beamline are analyzed on the fly, and by integrating experimental data with the inorganic crystal structure database (ICSD), we can substantially enhance the accuracy in classifying the structural phases across ternary phase spaces. We have used this approach to identify a novel magnetic phase with enhanced magnetic anisotropy which is a candidate for rare-earth free permanent magnet.

Kusne, Aaron Gilad [University of Maryland; Gao, Tieren [University of Maryland; Mehta, Apurva [SLAC National Accelerator Laboratory; Ke, Liqin [Ames Laboratory; Nguyen, Manh Cuong [Ames Laboratory; Ho, Kai-Ming [Ames Laboratory; Antropov, Vladimir [Ames Laboratory; Wang, Cai-Zhuang [Ames Laboratory; Kramer, Matthew J [Ames Laboratory; Long, Christian [University of Maryland; Takeuchi, Ichiro [University of Maryland

2014-09-15T23:59:59.000Z

178

High-Throughput Hacking of the Methylation Patterns in Breast Cancer by In vitro Transcription and Thymidine-Specific Cleavage Mass Array on MALDI-TOF Silico-Chip  

Science Journals Connector (OSTI)

...Research Article Cancer Genes and Genomics High-Throughput Hacking of the Methylation Patterns in Breast Cancer by In vitro Transcription...Supplement: Supplementary Data Supplementary Data High-throughput hacking of the methylation patterns in breast cancer by in vitro transcription...

Ramin Radpour; Mahdi Montazer Haghighi; Alex Xiu-Cheng Fan; Peyman Mohammadi Torbati; Sinuhe Hahn; Wolfgang Holzgreve; Xiao Yan Zhong

2008-11-01T23:59:59.000Z

179

In vivo robotics: the automation of neuroscience and other intact-system biological fields  

E-Print Network [OSTI]

Robotic and automation technologies have played a huge role in in vitro biological science, having proved critical for scientific endeavors such as genome sequencing and high-throughput screening. Robotic and automation ...

Forest, Craig R.

180

Scheduling screening inspections for replaceable and non-replaceable systems  

E-Print Network [OSTI]

This dissertation focuses on developing inspection schedules to detect non-self- announcing events which can only detected by inspections. Failures of protective sys- tems ,such as electronic equipments, alarms and stand-by systems, incipient...

Aral, Bahadir

2009-05-15T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Ionospheric Threat Mitigation by Geometry Screening in Ground-Based Augmentation Systems  

E-Print Network [OSTI]

Ionospheric Threat Mitigation by Geometry Screening in Ground-Based Augmentation Systems Jiyun Lee observed during severe ionospheric storms pose potential threats to the integrity of the Ground threats, because ionospheric gradients are not observable to the ground monitor if they impact

Stanford University

182

Screening reactor steam/water piping systems for water hammer  

SciTech Connect (OSTI)

A steam/water system possessing a certain combination of thermal, hydraulic and operational states, can, in certain geometries, lead to a steam bubble collapse induced water hammer. These states, operations, and geometries are identified. A procedure that can be used for identifying whether an unbuilt reactor system is prone to water hammer is proposed. For the most common water hammer, steam bubble collapse induced water hammer, six conditions must be met in order for one to occur. These are: (1) the pipe must be almost horizontal; (2) the subcooling must be greater than 20 C; (3) the L/D must be greater than 24; (4) the velocity must be low enough so that the pipe does not run full, i.e., the Froude number must be less than one; (5) there should be void nearby; (6) the pressure must be high enough so that significant damage occurs, that is the pressure should be above 10 atmospheres. Recommendations on how to avoid this kind of water hammer in both the design and the operation of the reactor system are made.

Griffith, P. [Massachusetts Inst. of Tech., Cambridge, MA (United States)

1997-09-01T23:59:59.000Z

183

A High-Throughput Fatty Acid Profiling Screen Reveals Novel Variations in Fatty Acid Biosynthesis in Chlamydomonas reinhardtii and Related Algae  

Science Journals Connector (OSTI)

...H2 for carrier gas and FID fuel and zero-grade air were provided...A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution...variation in the unicellular, green alga Chlamydomonas reinhardtii. PLoS...

Erin L. Pflaster; Michael J. Schwabe; Joyanne Becker; Melissa S. Wilkinson; Ashley Parmer; Thomas E. Clemente; Edgar B. Cahoon; Wayne R. Riekhof

2014-09-19T23:59:59.000Z

184

Abstract 5390: Development of a high-throughput screening assay to identify UHRF1 inhibitors via time-resolved fluorescence resonance energy transfer (TR-FRET)  

Science Journals Connector (OSTI)

...Association for Cancer Research April 15, 2013 meeting-abstract Immunology Poster...with a positive energy balance. Januaria...energy balance. [abstract]. In: Proceedings...Association for Cancer Research; 2013 Apr 6-10...

David A. Walker; Nicolas Wyhs; Hugh Giovinazzo; Srinivasan Yegnasubramanian; and William G. Nelson

2014-10-01T23:59:59.000Z

185

Combinatorial Chemistry & High Throughput Screening, 2007, 10, 111-119 111 1386-2073/07 $50.00+.00 2007 Bentham Science Publishers Ltd.  

E-Print Network [OSTI]

chemicals and intermediates [1]. For example, propylene can be converted into acrolein and acrylic acid carbons are weaker, propylene readily is oxidized to acrolein and to acrylic acid rather than

Senkan, Selim M.

186

Agenda from the U.S. Department of Energy's High Throughput Screening of Hydrogen Storage Materials Workshop on June 26, 2007  

Broader source: Energy.gov [DOE]

Agenda from the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

187

Advances in High-Throughput Screening for Drug Discovery The UIC Center for Clinical and Translational Science is sponsoring a translational technology symposium on  

E-Print Network [OSTI]

the Harvard/MIT Broad Institute, Sam Michael, from the NIH Chemical Genomics Center, Annie Mak, from the Genomics Institute of the Novartis Research Foundation, and Marcie Glicksman, from the Harvard Neuro-Scanning-Coupled Microscopy Sam Michael, Group Leader, Automation and Compound Management, NIH Chemical Genomics Center 11

Illinois at Chicago, University of

188

Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay  

Science Journals Connector (OSTI)

...for the repair of topoisomerase I-mediated DNA lesions. DNA Repair (Amst) 2003;2:1087-100. 8 El-Khamisy SF, Saifi GM, Weinfeld M, et al. Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1...

Christophe Marchand; Wendy A. Lea; Ajit Jadhav; Thomas S. Dexheimer; Christopher P. Austin; James Inglese; Yves Pommier; Anton Simeonov

2009-01-01T23:59:59.000Z

189

Apparatus for combinatorial screening of electrochemical materials  

DOE Patents [OSTI]

A high throughput combinatorial screening method and apparatus for the evaluation of electrochemical materials using a single voltage source (2) is disclosed wherein temperature changes arising from the application of an electrical load to a cell array (1) are used to evaluate the relative electrochemical efficiency of the materials comprising the array. The apparatus may include an array of electrochemical cells (1) that are connected to each other in parallel or in series, an electronic load (2) for applying a voltage or current to the electrochemical cells (1), and a device (3), external to the cells, for monitoring the relative temperature of each cell when the load is applied.

A high throughput combinatorial screening method and apparatus for the evaluation of electrochemical materials using a single voltage source (2) is disclosed wherein temperature changes arising from the application of an electrical load to a cell array (1) are used to evaluate the relative electrochemical efficiency of the materials comprising the array. The apparatus may include an array of electrochemical cells (1) that are connected to each other in parallel or in series, an electronic load (2) for applying a voltage or current to the electrochemical cells (1), and a device (3), external to the cells, for monitoring the relative temperature of each cell when the load is applied.

2009-12-15T23:59:59.000Z

190

Comparative evaluation of the sensitometric properties of screen-film systems and conventional dental receptors for intraoral radiography  

SciTech Connect (OSTI)

This investigation determined the sensitometric properties of 27 rare-earth screen-film combinations and compared them to E- and D-speed films and xeroradiography, the current standards for intraoral radiography. A series of exposures from base plus fog to film saturation were made to determine the Hurter and Driffield curve of each image receptor. The base plus fog, film saturation, speed, gamma, average gradient, and resolution were determined. When dental receptors and screen-film systems are compared on the basis of radiographic quality (contrast and resolution), many screen-film systems have similar resolution (greater than 10 line pairs/mm), significantly greater contrast (greater than 2.0), and a substantial speed advantage (greater than 10). Thus selected screen-film systems may be an alternative to conventional dental receptors for intraoral radiography.

Kircos, L.T.; Staninec, M.; Chou, L.

1989-12-01T23:59:59.000Z

191

HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

FLORIDA SOLAR ENERGY CENTER FLORIDA SOLAR ENERGY CENTER Creating Energy Independence Since 1975 A Research Institute of the University of Central Florida HT Combinatorial Screening of HT Combinatorial Screening of Novel Materials for High Capacity Novel Materials for High Capacity Hydrogen Storage Hydrogen Storage Ali T Ali T - - Raissi Raissi Director, Hydrogen & Fuel Cell R&D Director, Hydrogen & Fuel Cell R&D Division Division High Throughput/Combinatorial Analysis of Hydrogen Storage High Throughput/Combinatorial Analysis of Hydrogen Storage Materials Workshop, Bethesda, MD Materials Workshop, Bethesda, MD 26 June 2007 26 June 2007 This presentation does not contain any proprietary or confidential information 2 Objectives Objectives Develop (i.e. design, build, test and verify) a high

192

Charge screening and magnetic anisotropy in metallic rare-earth systems  

Science Journals Connector (OSTI)

The calculation of magnetic anisotropy constants is performed beyond the point-charge model for a continuous charge-density distribution of screening conduction electrons. An important role of the nonuniform electron density, in particular, of the Friedel oscillations, in the formation of crystal field is demonstrated. Such effects can modify strongly the effective ion (impurity) charge and even change its sign. This enables one to justify the anion model, which is often used for discussing experimental data on hydrogen-containing systems. Possible applications to the pure rare-earth metals and RCo5 (R=rare earth) compounds are discussed. The deformation of magnetic structure near the interstitial positive muon owing to the strong local anisotropy, and the corresponding contribution to the dipole field at the muon are considered.

V. Yu. Irkhin and Yu. P. Irkhin

1998-02-01T23:59:59.000Z

193

Novel System for Recalcitrance Screening Will Reduce Biofuels Production Costs, The Spectrum of Clean Energy Innovation (Fact Sheet)  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

This new system will allow researchers to much more rapidly screen large numbers of samples This new system will allow researchers to much more rapidly screen large numbers of samples and identify the most promising biomass feedstocks for higher efficiency and lower cost bio- fuels conversion processes. NREL will be screening thousands of variants of different biomass feedstocks to link genetic traits with environmental factors that can enhance biomass conver- sion efficiencies. Identifying the genes controlling the anatomical, chemical, and morphologi- cal features of biomass is essential to develop the next generation of low-cost, easily convert- ible biomass feedstocks. To identify superior performing biomass feedstocks using approaches that account for natural diversity and randomness, researchers must measure the cell wall chemistry and recalcitrance

194

Use of Time-Aggregated Data in Economic Screening Analyses of Combined Heat and Power Systems  

SciTech Connect (OSTI)

Combined heat and power (CHP) projects (also known as cogeneration projects) usually undergo a series of assessments and viability checks before any commitment is made. A screening analysis, with electrical and thermal loads characterized on an annual basis, may be performed initially to quickly determine the economic viability of the proposed project. Screening analyses using time-aggregated data do not reflect several critical cost influences, however. Seasonal and diurnal variations in electrical and thermal loads, as well as time-of-use utility pricing structures, can have a dramatic impact on the economics. A more accurate economic assessment requires additional detailed data on electrical and thermal demand (e.g., hourly load data), which may not be readily available for the specific facility under study. Recent developments in CHP evaluation tools, however, can generate the needed hourly data through the use of historical data libraries and building simulation. This article utilizes model-generated hourly load data for four potential CHP applications and compares the calculated cost savings of a CHP system when evaluated on a time-aggregated (i.e., annual) basis to the savings when evaluated on an hour-by-hour basis. It is observed that the simple, aggregated analysis forecasts much greater savings (i.e., greater economic viability) than the more detailed hourly analysis. The findings confirm that the simpler tool produces results with a much more optimistic outlook, which, if taken by itself, might lead to erroneous project decisions. The more rigorous approach, being more reflective of actual requirements and conditions, presents a more accurate economic comparison of the alternatives, which, in turn, leads to better decision risk management.

Hudson II, Carl Randy [ORNL

2004-09-01T23:59:59.000Z

195

Economic Screening of Geologic Sequestration Options in the United States with a Carbon Management Geographic Information System  

SciTech Connect (OSTI)

Developing a carbon management strategy is a formidable task for nations as well as individual companies. It is often difficult to understand what options are available, let alone determine which may be optimal. In response to the need for a better understanding of complex carbon management options, Battelle has developed a state-of-the-art Geographic Information System (GIS) model with economic screening capability focused on carbon capture and geologic sequestration opportunities in the United States. This paper describes the development of this GIS-based economic screening model and demonstrates its use for carbon management analysis.

Dahowski, Robert T. (BATTELLE (PACIFIC NW LAB)); Dooley, James J. (BATTELLE (PACIFIC NW LAB)); Brown, Daryl R. (BATTELLE (PACIFIC NW LAB)); Stephan, Alex J. (BATTELLE (PACIFIC NW LAB)); Badie I. Morsi

2001-10-19T23:59:59.000Z

196

High-Throughput Plasmonic Nanolithography  

E-Print Network [OSTI]

Some of the materials allow reversible phase change and areto change the phase for a semispherical material volume withto change the phase for a semispherical material volume of

Pan, Liang

2010-01-01T23:59:59.000Z

197

High throughput reproducible cantilever functionalization  

DOE Patents [OSTI]

A method for functionalizing cantilevers is provided that includes providing a holder having a plurality of channels each having a width for accepting a cantilever probe and a plurality of probes. A plurality of cantilever probes are fastened to the plurality of channels of the holder by the spring clips. The wells of a well plate are filled with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels. Each cantilever probe that is fastened within the plurality of channels of the holder is applied to the functionalization solution that is contained in the wells of the well plate.

Evans, Barbara R; Lee, Ida

2014-01-21T23:59:59.000Z

198

High-Throughput Plasmonic Nanolithography  

E-Print Network [OSTI]

by a thin layer of Perfluoropolyether (PFPE) as a lubricant2-nm thick lubricant Perfluoropolyether (PFPE) was also dip-

Pan, Liang

2010-01-01T23:59:59.000Z

199

High-Throughput Plasmonic Nanolithography  

E-Print Network [OSTI]

gap between the flying PL arrays and disk surface. (a) (b) (gap between the flying PL arrays and disk surface. As shown3 N 4 overcoats. Both disks and flying heads were examined

Pan, Liang

2010-01-01T23:59:59.000Z

200

Plant Phenotype Characterization System  

SciTech Connect (OSTI)

This report is the final scientific report for the DOE Inventions and Innovations Project: Plant Phenotype Characterization System, DE-FG36-04GO14334. The period of performance was September 30, 2004 through July 15, 2005. The project objective is to demonstrate the viability of a new scientific instrument concept for the study of plant root systems. The root systems of plants are thought to be important in plant yield and thus important to DOE goals in renewable energy sources. The scientific study and understanding of plant root systems is hampered by the difficulty in observing root activity and the inadequacy of existing root study instrumentation options. We have demonstrated a high throughput, non-invasive, high resolution technique for visualizing plant root systems in-situ. Our approach is based upon low-energy x-ray radiography and the use of containers and substrates (artificial soil) which are virtually transparent to x-rays. The system allows us to germinate and grow plant specimens in our containers and substrates and to generate x-ray images of the developing root system over time. The same plant can be imaged at different times in its development. The system can be used for root studies in plant physiology, plant morphology, plant breeding, plant functional genomics and plant genotype screening.

Daniel W McDonald; Ronald B Michaels

2005-09-09T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Development of a trace explosives detection portal for personnel screening  

SciTech Connect (OSTI)

The authors discuss the development, design, and operation of a walk-through trace detection portal designed to screen personnel for explosives. Developed at Sandia National Laboratories (SNL) with primary funding from the Federal Aviation Administration (FAA) and additional support from the Department of Energy office of Safeguards and Security, this portal is intended primarily for use in airport terminals and in other localities where a very high throughput of pedestrian traffic is combined with stringent security requirements. The portal is capable of detecting both vapor and particulate contamination, with the collection of explosive material being based upon the entrainment of that material in air flows over the body of the person being screened. This portal is capable of detecting most types of common high explosives of interest to the FAA. The authors discuss the results of field testing of the portal in the Albuquerque International Airport in September, 1997 and more recent steps towards commercialization of the portal.

Parmeter, J.E.; Linker, K.L.; Rhykerd, C.L. Jr.; Bouchier, F.A.; Hannum, D.W.

1998-08-01T23:59:59.000Z

202

From screen to structure with a harvestable microfluidic device  

SciTech Connect (OSTI)

Advances in automation have facilitated the widespread adoption of high-throughput vapor-diffusion methods for initial crystallization screening. However, for many proteins, screening thousands of crystallization conditions fails to yield crystals of sufficient quality for structural characterization. Here, the rates of crystal identification for thaumatin, catalase and myoglobin using microfluidic Crystal Former devices and sitting-drop vapour-diffusion plates are compared. It is shown that the Crystal Former results in a greater number of identified initial crystallization conditions compared with vapor diffusion. Furthermore, crystals of thaumatin and lysozyme obtained in the Crystal Former were used directly for structure determination both in situ and upon harvesting and cryocooling. On the basis of these results, a crystallization strategy is proposed that uses multiple methods with distinct kinetic trajectories through the protein phase diagram to increase the output of crystallization pipelines.

Stojanoff V.; Jakonic, J.; Oren, D.A.; Nagarajan, V.; Navarro Poulsen, J.C.; Adams-Cioaba, M.A.; Bergfors, T. and Sommer, M.O.A.

2011-06-21T23:59:59.000Z

203

A fluorescent screening platform for the rapid evaluation of chemicals in cellular reprogramming  

Science Journals Connector (OSTI)

Current strategies to monitor reprogramming into induced pluripotent stem cells (iPSCs) are limited in that they rely on the recognition of advanced stage biomarkers or they involve the transduction of genetically-modified cells. These limitations are particularly problematic in high-throughput screenings where cell availability, low cost and a rapid experimental protocol are critical issues. Herein we report the application of a pluripotent stem cell fluorescent probe (i.e. CDy1) as a reporter for the rapid screening of chemicals in reprogramming iPSCs. \\{CDy1\\} stains early-stage iPSCs at 7dpi as well as matured iPSCs; hence it can partially overcome the slow kinetics of the reprogramming process. As a proof of concept, we employed a CDy1-based screening in 384 well-plates to examine the effect of newly synthesized hydroxamic acid derivatives in reprogramming mouse fibroblasts transduced with Oct4, Sox2 and Klf-4 without c-Myc. One compound (126) was identified as a reprogramming enhancer by 2.5-fold and we confirmed that 126 behaves as a histone deacetylase (HDAC) inhibitor. The successful identification of novel small molecules enhancing the generation of iPSCs by means of a rapid and simple protocol demonstrates the suitability of this CDy1-based screening platform for the large scale and high-throughput evaluation of iPSC modulators.

Marc Vendrell; Sung-Jin Park; Yogeswari Chandran; Chi-Lik Ken Lee; Hyung-Ho Ha; Nam-Young Kang; Seong-Wook Yun; Young-Tae Chang

2012-01-01T23:59:59.000Z

204

A screening model to explore planning decisions in automotive manufacturing systems under demand uncertainty  

E-Print Network [OSTI]

Large-scale, complex engineering systems, as for automotive manufacturing, often require significant capital investment and resources for systems configuration. Furthermore, these systems operate in environments that are ...

Yang, Yingxia

2009-01-01T23:59:59.000Z

205

Preliminary Screening  

Broader source: Energy.gov [DOE]

The first step in assessing renewable energy options is to conduct a preliminary screening to decide which technologies are worth investigating and which can be eliminated immediately. Preliminary...

206

Exploring flexible strategies in engineering systems using screening models : applications to offshore petroleum projects  

E-Print Network [OSTI]

Engineering Systems, such as offshore petroleum exploration and production systems, generally require a significant amount of capital investment under various technical and market uncertainties. Choosing appropriate designs ...

Lin, Jijun, Ph. D. Massachusetts Institute of Technology

2009-01-01T23:59:59.000Z

207

Objective: Determine the energy use of two greenhouse insulation technologies (a bubble insulation system and an energy/shade screen) retrofitted into plastic covered greenhouses, and compare the  

E-Print Network [OSTI]

compared to the unimproved house. The bubble insulation system was more energy efficient than the other two roughly twice the savings stated above. Novel Approaches to Improve Energy Efficiency in Northern New system and an energy/shade screen) retrofitted into plastic covered greenhouses, and compare

Vermont, University of

208

Screening of mixed surfactant systems: Phase behavior studies and CT imaging of surfactant-enhanced oil recovery experiments  

SciTech Connect (OSTI)

A systematic chemical screening study was conducted on selected anionic-nonionic and nonionic-nonionic systems. The objective of the study was to evaluate and determine combinations of these surfactants that would exhibit favorable phase behavior and solubilization capacity. The effects of different parameters including (a) salinity, (b) temperature, (c) alkane carbon number, (c) hydrophilic/lipophilic balance (HLB) of nonionic component, and (d) type of surfactant on the behavior of the overall chemical system were evaluated. The current work was conducted using a series of ethoxylated nonionic surfactants in combinations of several anionic systems with various hydrocarbons. Efforts to correlate the behavior of these mixed systems led to the development of several models for the chemical systems tested. The models were used to compare the different systems and provided some guidelines for formulating them to account for variations in salinity, oil hydrocarbon number, and temperature. The models were also evaluated to determine conformance with the results from experimental measurements. The models provided good agreement with experimental results. X-ray computed tomography (CT) was used to study fluid distributions during chemical enhanced oil recovery experiments. CT-monitored corefloods were conducted to examine the effect of changing surfactant slug size injection on oil bank formation and propagation. Reducing surfactant slug size resulted in lower total oil production. Oil recovery results, however, did not correlate with slug size for the low-concentration, alkaline, mixed surfactant system used in these tests. The CT measurements showed that polymer mobility control and core features also affected the overall oil recovery results.

Llave, F.M.; Gall, B.L.; Lorenz, P.B.; Cook, I.M.; Scott, L.J.

1993-11-01T23:59:59.000Z

209

Identification of a Broad-Spectrum Antiviral Small Molecule against Severe Acute Respiratory Syndrome Coronavirus and Ebola, Hendra, and Nipah Viruses by Using a Novel High-Throughput Screening Assay  

Science Journals Connector (OSTI)

...processing of the Hendra virus fusion protein. J. Virol. 79 :12714-12720...fusogenic form of the Nipah virus fusion protein requires proteolytic...Jin, T Van Phan, ML Smythe, HF White, and SW Oliver. 1993...syndrome coronavirus class I fusion protein upstream of rather than...

Hatem A. Elshabrawy; Jilao Fan; Christine S. Haddad; Kiira Ratia; Christopher C. Broder; Michael Caffrey; Bellur S. Prabhakar

2014-02-05T23:59:59.000Z

210

Biochemical Screening of Pyrimidine Antimetabolites: I. Systems with Oxidative Energy Source  

Science Journals Connector (OSTI)

...Systems with Oxidative Energy Source* JOSEPHE. STONEANDVANR...to the uridine nucleo tides. Normal rat liver cytoplasm...furnished the source of energy for the reactions. A...of an agent upon the energy source, the absolute...ics to uridine nucleo- tides, could be used for production...

Joseph E. Stone and Van R. Potter

1956-12-01T23:59:59.000Z

211

System and method for generating and/or screening potential metal-organic frameworks  

DOE Patents [OSTI]

A system and method for systematically generating potential metal-organic framework (MOFs) structures given an input library of building blocks is provided herein. One or more material properties of the potential MOFs are evaluated using computational simulations. A range of material properties (surface area, pore volume, pore size distribution, powder x-ray diffraction pattern, methane adsorption capability, and the like) can be estimated, and in doing so, illuminate unidentified structure-property relationships that may only have been recognized by taking a global view of MOF structures. In addition to identifying structure-property relationships, this systematic approach to identify the MOFs of interest is used to identify one or more MOFs that may be useful for high pressure methane storage.

Wilmer, Christopher E; Leaf, Michael; Snurr, Randall Q; Farha, Omar K; Hupp, Joseph T

2014-12-02T23:59:59.000Z

212

Energy Efficient Nanoelectronic System Design  

E-Print Network [OSTI]

Throughput ... Power Hungry !! Battery Hungry !! 05/21/2013 4 #12;Electronic System: Many Others (Same Story) Smarter ... Faster ... High Throughput ... Power Hungry !! Battery Hungry !! 05/21/2013 5 #12;Battery://www.newairplane.com One 787 Battery: 12 Cells / 32 V DC 05/21/2013 6 #12;Why Energy Efficient Design ? Environmental

Mohanty, Saraju P.

213

Screening in multilayer graphene  

Science Journals Connector (OSTI)

In this paper, we study the static polarization in ABC-stacked multilayer graphene. Since the density of states diverges for these systems if the number of layers exceeds three, screening effects are expected to be important. In the random phase approximation, screening can be included through the polarization. We derive an analytical integral expression for the polarization in both the full-band model and an effective two-band model. Numerical evaluation of these integrals is very time consuming in the full-band model. Hence, for ABC-stacked trilayer graphene, we use the two-band model to calculate the low momentum part of the polarization. The results for the two-band model are universal, i.e., independent of doping. The high momentum part is linear and is determined by calculating two points, such that we can determine the slope. For ABC stacked trilayer graphene, the slope is given by three times the monolayer value. We compare our results to previous ones in the literature and discuss the similarities and discrepancies. Our results can be used to include screening in ABC-stacked multilayer systems in a way that all the characteristics of the polarization function are included. The numerical results for the polarization of trilayer graphene are used to sketch the screened potential.

Ralph van Gelderen; Richard Olsen; C. Morais Smith

2013-09-09T23:59:59.000Z

214

BCHP Screening Tool | Open Energy Information  

Open Energy Info (EERE)

BCHP Screening Tool BCHP Screening Tool Jump to: navigation, search Tool Summary LAUNCH TOOL Name: BCHP Screening Tool Agency/Company /Organization: Oak Ridge National Laboratory Sector: Energy Focus Area: Buildings, Industry Phase: Determine Baseline, Develop Goals Resource Type: Software/modeling tools, Guide/manual User Interface: Desktop Application Website: www.coolingheatingpower.org/about/bchp-screening-tool.php References: http://www.coolingheatingpower.org/about/bchp-screening-tool.php Logo: BCHP Screening Tool The BCHP Screening Tool is software that can be used to estimate the energy consumption and economics of CHP systems in commercial buildings. The BCHP Screening Tool is software that can be used to estimate the energy consumption and economics of CHP systems in commercial buildings. This tool

215

Projection screen having reduced ambient light scattering  

DOE Patents [OSTI]

An apparatus and method for improving the contrast between incident projected light and ambient light reflected from a projection screen are described. The efficiency of the projection screen for reflection of the projected light remains high, while permitting the projection screen to be utilized in a brightly lighted room. Light power requirements from the projection system utilized may be reduced.

Sweatt, William C. (Albuquerque, NM)

2010-05-11T23:59:59.000Z

216

Wafer screening device and methods for wafer screening  

DOE Patents [OSTI]

Wafer breakage is a serious problem in the photovoltaic industry because a large fraction of wafers (between 5 and 10%) break during solar cell/module fabrication. The major cause of this excessive wafer breakage is that these wafers have residual microcracks--microcracks that were not completely etched. Additional propensity for breakage is caused by texture etching and incomplete edge grinding. To eliminate the cost of processing the wafers that break, it is best to remove them prior to cell fabrication. Some attempts have been made to develop optical techniques to detect microcracks. Unfortunately, it is very difficult to detect microcracks that are embedded within the roughness/texture of the wafers. Furthermore, even if such detection is successful, it is not straightforward to relate them to wafer breakage. We believe that the best way to isolate the wafers with fatal microcracks is to apply a stress to wafers--a stress that mimics the highest stress during cell/module processing. If a wafer survives this stress, it has a high probability of surviving without breakage during cell/module fabrication. Based on this, we have developed a high throughput, noncontact method for applying a predetermined stress to a wafer. The wafers are carried on a belt through a chamber that illuminates the wafer with an intense light of a predetermined intensity distribution that can be varied by changing the power to the light source. As the wafers move under the light source, each wafer undergoes a dynamic temperature profile that produces a preset elastic stress. If this stress exceeds the wafer strength, the wafer will break. The broken wafers are separated early, eliminating cost of processing into cell/module. We will describe details of the system and show comparison of breakage statistics with the breakage on a production line.

Sopori, Bhushan; Rupnowski, Przemyslaw

2014-07-15T23:59:59.000Z

217

Characterization of aqueous two phase systems by combining lab-on-a-chip technology with robotic liquid handling stations  

Science Journals Connector (OSTI)

Abstract Over the last decade, the use of design of experiment approaches in combination with fully automated high throughput (HTP) compatible screenings supported by robotic liquid handling stations (LHS), adequate fast analytics and data processing has been developed in the biopharmaceutical industry into a strategy of high throughput process development (HTPD) resulting in lower experimental effort, sample reduction and an overall higher degree of process optimization. Apart from HTP technologies, lab-on-a-chip technology has experienced an enormous growth in the last years and allows further reduction of sample consumption. A combination of LHS and lab-on-a-chip technology is highly desirable and realized in the present work to characterize aqueous two phase systems with respect to tie lines. In particular, a new high throughput compatible approach for the characterization of aqueous two phase systems regarding tie lines by exploiting differences in phase densities is presented. Densities were measured by a standalone micro fluidic liquid density sensor, which was integrated into a liquid handling station by means of a developed generic Tip2World interface. This combination of liquid handling stations and lab-on-a-chip technology enables fast, fully automated, and highly accurate density measurements. The presented approach was used to determine the phase diagram of \\{ATPSs\\} composed of potassium phosphate (pH 7) and polyethylene glycol (PEG) with a molecular weight of 300, 400, 600 and 1000Da respectively in the presence and in the absence of 3% (w/w) sodium chloride. Considering the whole ATPS characterization process, two complete \\{ATPSs\\} could be characterized within 24h, including four runs per ATPS for binodal curve determination (less than 45min/run), and tie line determination (less than 45min/run for ATPS preparation and 8h for density determination), which can be performed fully automated over night without requiring man power. The presented methodology provides a cost, time and material effective approach for characterization of ATPS phase diagram on base on highly accurate and comprehensive data. By this means the derived data opens the door for a more detailed description of ATPS towards generating mechanistic based models, since molecular approaches such as MD simulations or molecular descriptions along the line of QSAR heavily rely on accurate and comprehensive data.

Sven Amrhein; Marie-Luise Schwab; Marc Hoffmann; Jrgen Hubbuch

2014-01-01T23:59:59.000Z

218

DfX for Nanoelectronic Embedded Systems  

E-Print Network [OSTI]

of nanoscale devices. Gate Gate Gate Source D rain Graphene Layer High-K nano-CMOS Triple Gate Graphene Systems: Common Story Smarter ... Faster ... High Throughput ... Power Hungry !! Battery Hungry !! 12/18/2013 25 #12;Battery Dependency: Not Overstated Boeing 787's across the globe were grounded in early 2013

Mohanty, Saraju P.

219

High Throughput Materials Characterization John M. Gregoire  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and groups where these activities take place are listed in the red boxes in the diagram above. A truly productive HiTp materials discovery pipeline, not unlike a structural...

220

A high-throughput distributed DNA  

E-Print Network [OSTI]

of royalty provided that (1) each reproduction is done without alteration and (2) the Journal reference, of this paper may be copied or distributed royalty free without further permission by computer-based and other

Weller, Jennifer Walsh

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

High-throughput hyperdimensional vertebrate phenotyping  

E-Print Network [OSTI]

Most gene mutations and biologically active molecules cause complex responses in animals that cannot be predicted by cell culture models. Yet animal studies remain too slow and their analyses are often limited to only a ...

Pardo-Martin, Carlos

222

High Throughput Single Molecule Investigation of Transcription  

E-Print Network [OSTI]

Dots. Nano Letters 9, 15981603. 4. Ebenstein, Y. , Gassman,Dots. Nano Letters 9, 1598-1603 (2009). Ebenstein, Y. ,

Kim, Soohong

2012-01-01T23:59:59.000Z

223

High Throughput Single Molecule Investigation of Transcription  

E-Print Network [OSTI]

Single Molecule Protein Folding in a Coaxial Mixer. Biophys.Kinetic Studies of Protein Folding. Anal. Chem. 76, 7169-Molecule Measurement of Protein Folding Kinetics . Science

Kim, Soohong

2012-01-01T23:59:59.000Z

224

Approaches to High Throughput Physical Organic Chemistry  

E-Print Network [OSTI]

compounds, using positive electrospray MS as the sole analytical tool. A version of the construct allowed HT reactivity profiling to be carried out on a range of ten carboxylic acids, ten aldehydes and ten isonitriles in the Ugi 4-component condensation...

Portal, Christophe

2008-01-01T23:59:59.000Z

225

Optimal Assembly for High Throughput Shotgun Sequencing  

E-Print Network [OSTI]

suf- ficient conditions for success in terms of repeat-between the sufficient condition guaranteeing the success ofby a read). Condition (a) K > ? interleaved for success of

Bresler, Guy; Bresler, Ma'ayan; Tse, David

2013-01-01T23:59:59.000Z

226

High Throughput Single Molecule Investigation of Transcription.  

E-Print Network [OSTI]

??RNA Polymerase (RNAP) is a crucial protein molecule that decodes the information stored in DNA as base pair sequences, through a process called transcription. The (more)

Kim, Soohong

2012-01-01T23:59:59.000Z

227

High-throughput proteomics : optical approaches.  

SciTech Connect (OSTI)

Realistic cell models could greatly accelerate our ability to engineer biochemical pathways and the production of valuable organic products, which would be of great use in the development of biofuels, pharmaceuticals, and the crops for the next green revolution. However, this level of engineering will require a great deal more knowledge about the mechanisms of life than is currently available. In particular, we need to understand the interactome (which proteins interact) as it is situated in the three dimensional geometry of the cell (i.e., a situated interactome), and the regulation/dynamics of these interactions. Methods for optical proteomics have become available that allow the monitoring and even disruption/control of interacting proteins in living cells. Here, a range of these methods is reviewed with respect to their role in elucidating the interactome and the relevant spatial localizations. Development of these technologies and their integration into the core competencies of research organizations can position whole institutions and teams of researchers to lead in both the fundamental science and the engineering applications of cellular biology. That leadership could be particularly important with respect to problems of national urgency centered around security, biofuels, and healthcare.

Davidson, George S.

2008-09-01T23:59:59.000Z

228

The Harvard Clean Energy Project: Large-Scale Computational Screening and Design of Organic Photovoltaics on the World Community Grid  

Science Journals Connector (OSTI)

The Harvard Clean Energy Project: Large-Scale Computational Screening and Design of Organic Photovoltaics on the World Community Grid ... The Clean Energy Project stands out from other computational materials science approaches as it combines conventional modeling with strategies from modern drug discovery:(54-61) CEP features an automated, high-throughput infrastructure for a systematic screening of millions of OPV candidates at a first-principles electronic structure level. ... We have developed four new functionals that overcome the above-mentioned difficulties: (a) M06, a hybrid meta functional, is a functional with good accuracy "across-the-board" for transition metals, main group thermochem., medium-range correlation energy, and barrier heights; (b) M06-2X, another hybrid meta functional, is not good for transition metals but has excellent performance for main group chem., predicts accurate valence and Rydberg electronic excitation energies, and is an excellent functional for arom.-arom. ...

Johannes Hachmann; Roberto Olivares-Amaya; Sule Atahan-Evrenk; Carlos Amador-Bedolla; Roel S. Sa?nchez-Carrera; Aryeh Gold-Parker; Leslie Vogt; Anna M. Brockway; Ala?n Aspuru-Guzik

2011-08-22T23:59:59.000Z

229

Erkitinib, a novel EGFR tyrosine kinase inhibitor screened using a ProteoChip system from a phytochemical library  

SciTech Connect (OSTI)

Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer. Therefore PTK inhibitors are currently under intensive investigation as potential drug candidates. Herein, we report on a ProteoChip-based screening of an epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor, Erkitinibs, from phytochemical libraries. PLC-{gamma}-1 was used as a substrate immobilized on a ProteoChip and incubated with an EGFR kinase to phosphorylate tyrosine residues of the substrate, followed by a fluorescence detection of the substrate recognized by a phospho-specific monoclonal antibody. Erkitinibs inhibited HeLa cell proliferation in a dose-dependent manner. In conclusion, these data suggest that Erkitinibs can be a specific inhibitor of an EGFR kinase and can be further developed as a potent anti-tumor agent.

Kim, Eung-Yoon; Choi, Young-Jin [Biochip Research Center, Hoseo University, Asan 336-795 (Korea, Republic of) [Biochip Research Center, Hoseo University, Asan 336-795 (Korea, Republic of); Innopharmascreen, Inc., Asan 336-795 (Korea, Republic of); Park, Chan-Won [Biochip Research Center, Hoseo University, Asan 336-795 (Korea, Republic of) [Biochip Research Center, Hoseo University, Asan 336-795 (Korea, Republic of); Dept. of Biological Science, Hoseo University, Asan 336-795 (Korea, Republic of); Kang, In-Cheol, E-mail: ickang@hoseo.edu [Biochip Research Center, Hoseo University, Asan 336-795 (Korea, Republic of) [Biochip Research Center, Hoseo University, Asan 336-795 (Korea, Republic of); Dept. of Biological Science, Hoseo University, Asan 336-795 (Korea, Republic of); Innopharmascreen, Inc., Asan 336-795 (Korea, Republic of)

2009-11-20T23:59:59.000Z

230

Digital Measures screen changes 1 Digital Measures screen changes 2  

E-Print Network [OSTI]

Digital Measures screen changes 1 #12; Digital Measures screen changes 2 #12; Digital Measures screen changes 3 #12; Digital Measures screen changes 4 #12; Digital Measures screen changes 5 #12; Digital Measures screen changes 6 #12; Digital Measures screen changes 7 #12

Barrash, Warren

231

DfX for Nanoelectronic Circuits and Systems  

E-Print Network [OSTI]

of nanoscale devices. Gate Gate Gate Source D rain Graphene Layer High-K nano-CMOS Triple Gate Graphene Systems: Common Story Smarter ... Faster ... High Throughput ... Power Hungry !! Battery Hungry !! 12/23/2013 25 #12;Battery Dependency: Not Overstated Boeing 787's across the globe were grounded in early 2013

Mohanty, Saraju P.

232

Reverse Ecology: From Systems to Environments and Back  

E-Print Network [OSTI]

Chapter 15 Reverse Ecology: From Systems to Environments and Back Roie Levy and Elhanan Borenstein the environments in which they evolved and are adapted to. Re- verse Ecology--an emerging new frontier's ecology. The Reverse Ecology framework facilitates the translation of high-throughput genomic data

Borenstein, Elhanan

233

Breast-Cancer Screening  

Science Journals Connector (OSTI)

....79 to 0.99) for death from breast cancer, the USPSTF previously recommended routine screening mammography for women in this age group. Since it had been argued that the benefit of screening women in their 40s could largely be attributed to the detection of cancers after the age of 50 years in women... This article reviews current recommendations for breast-cancer screening and the supporting evidence, including the controversy regarding mammographic screening of women in their 40s.

Warner E.

2011-09-15T23:59:59.000Z

234

Screening | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Screening Screening Screening October 16, 2013 - 5:17pm Addthis Screening is typically performed by an outside party or an independent renewable energy expert or team. It is a review of the possible technology options that identifies dead-ends and further narrows the list to probable technologies for the project. A screening provides a preliminary assessment of how much energy could be produced by various renewable energy technologies and conducts a high-level analysis of expected costs and savings, utility considerations, and potential incentives. Federal agencies can analyze specific sites or conduct an agency-wide screening across properties to decide which areas have the greatest renewable energy potential. When conducted in conjunction with a new construction project or major renovation, an agency should get results from

235

Screening study for evaluation of the potential for system 80+ to consume excess plutonium - Volume 2. Final report  

SciTech Connect (OSTI)

As part of the U.S. effort to evaluate technologies offering solutions for the safe disposal or utilization of surplus nuclear materials, the fiscal year 1993 Energy and Water Appropriations legislation provided the Department of Energy (DOE) the necessary funds to conduct multi-phased studies to determine the technical feasibility of using reactor technologies for the triple mission of burning weapons grade plutonium, producing tritium for the existing smaller weapons stockpile, and generating commercial electricity. DOE limited the studies to five advanced reactor designs. Among the technologies selected is the ABB-Combustion Engineering (ABB-CE) System 80+. The DOE study, currently in Phase ID, is proceeding with a more detailed evaluation of the design`s capability for plutonium disposition.

Not Available

1994-04-30T23:59:59.000Z

236

Medical Screening Protocol for the Former Worker Medical Screening...  

Office of Environmental Management (EM)

Medical Screening Program (FWP) is to provide interested former workers with targeted testing to screen for selected adverse health effects potentially related to their work in...

237

Clad Degradation - FEPs Screening Arguments  

SciTech Connect (OSTI)

The purpose of this report is to document the screening of the cladding degradation features, events, and processes (FEPs) for commercial spent nuclear fuel (CSNF). This report also addresses the effect of some FEPs on both the cladding and the CSNF, DSNF, and HLW waste forms where it was considered appropriate to address the effects on both materials together. This report summarizes the work of others to screen clad degradation FEPs in a manner consistent with, and used in, the Total System Performance Assessment-License Application (TSPA-LA). This document was prepared according to ''Technical Work Plan for Waste Form Degradation Modeling, Testing, and Analyses in Support of LA'' (BSC 2004a [DIRS 167796]).

E. Siegmann

2004-03-17T23:59:59.000Z

238

Solar Site Screening Decision Tree  

Broader source: Energy.gov [DOE]

The solar site screening decision tree guides users through a process for screening sites for their suitability for future redevelopment with solar photovoltaic energy. EPA encourages the...

239

THOMPSON ET AL.: RAPID SPECTRAL CLOUD SCREENING 1 Rapid spectral cloud screening onboard aircraft and  

E-Print Network [OSTI]

--Imaging Spectroscopy, Lossy Compression, Cloud Screening, Pattern Recognition, Real Time Systems I. INTRODUCTION FUTURE NASA Earth science missions will face unprece- dented data volumes. Data product sizes and produc- tion

240

GPU Computational Screening  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GPU Computational Screening of Carbon Capture Materials J. Kim 1 , A Koniges 1 , R. Martin 1 , M. Haranczyk 1 , J. Swisher 2 , and B. Smit 1,2 1 Lawrence Berkeley National...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Electrostatic screening by semiconductors  

E-Print Network [OSTI]

Electrostatic screening by semiconductors is studied, hics. applying the Thomas-Fermi theory. The semiconductor is treated as a medium with dielectric constant e due to vocalizable atoms, with force charge due to electrons. Two models...

Krcmar, Maja

2012-06-07T23:59:59.000Z

242

Algorithm for Screening Phasor Measurement Unit Data for Power System Events and Categories and Common Characteristics for Events Seen in Phasor Measurement Unit Relative Phase-Angle Differences and Frequency Signals  

SciTech Connect (OSTI)

A network of multiple phasor measurement units (PMU) was created, set up, and maintained at the University of Texas at Austin to obtain actual power system measurements for power system analysis. Power system analysis in this report covers a variety of time ranges, such as short- term analysis for power system disturbances and their effects on power system behavior and long- term power system behavior using modal analysis. The first objective of this report is to screen the PMU data for events. The second objective of the report is to identify and describe common characteristics extracted from power system events as measured by PMUs. The numerical characteristics for each category and how these characteristics are used to create selection rules for the algorithm are also described. Trends in PMU data related to different levels and fluctuations in wind power output are also examined.

Allen, A.; Santoso, S.; Muljadi, E.

2013-08-01T23:59:59.000Z

243

Image-Based Chemical Screening Identifies Drug Efflux Inhibitors in Lung Cancer Cells  

Science Journals Connector (OSTI)

...high-throughput studies using the SP technique. On the other hand, recently, automated image analysis aided by high-performance computing has enabled rapid advances in the development of high-throughput image-based assays (19-22). Considering...

Xiaofeng Xia; Jian Yang; Fuhai Li; Ying Li; Xiaobo Zhou; Yue Dai; Stephen T.C. Wong

2010-10-01T23:59:59.000Z

244

Preliminary Screening Analysis for the Environmental Risk Evaluation System: Task 2.1.1: Evaluating Effects of Stressors Fiscal Year 2010 Progress Report: Environmental Effects of Marine and Hydrokinetic Energy  

SciTech Connect (OSTI)

Possible environmental effects of marine and hydrokinetic (MHK) energy development are not well understood, and yet regulatory agencies are required to make decisions in spite of substantial uncertainty about environmental impacts and their long-term effects. An understanding of risk associated with likely interactions between MHK installations and aquatic receptors, including animals, habitats, and ecosystems, can help reduce the level of uncertainty and focus regulatory actions and scientific studies on interactions of most concern. As a first step in developing the Pacific Northwest National Laboratory (PNNL) Environmental Risk Evaluation System (ERES), PNNL scientists conducted a preliminary risk screening analysis on three initial MHK cases - a tidal project in Puget Sound using Open Hydro turbines, a wave project off the coast of Oregon using Ocean Power Technologies point attenuator buoys, and a riverine current project in the Mississippi River using Free Flow turbines. Through an iterative process, the screening analysis revealed that top-tier stressors in all three cases were the effects of the dynamic physical presence of the device (e.g., strike), accidents, and effects of the static physical presence of the device (e.g., habitat alteration). Receptor interactions with these stressors at the four highest tiers of risk were dominated by marine mammals (cetaceans and pinnipeds) and birds (diving and non-diving); only the riverine case (Free Flow) included different receptors in the third tier (fish) and the fourth tier (benthic invertebrates). Although this screening analysis provides a preliminary analysis of vulnerability of environmental receptors to stressors associated with MHK installations, probability analysis, especially of risk associated with chemical toxicity and accidents such as oil spills or lost gear, will be necessary to further understand high-priority risks. Subject matter expert review of this process and results is required and is planned for the first quarter of FY11. Once expert review is finalized, the screening analysis phase of ERES will be complete.

Anderson, Richard M.; Copping, Andrea E.; Van Cleve, Frances B.

2010-11-15T23:59:59.000Z

245

Hydropower Potential Screening Study  

E-Print Network [OSTI]

Hydropower Potential Screening Study Gillian Charles GRAC 5/28/14 #12;Latest Hydropower Potential Study Creating a Buzz 2014 DOE study on undeveloped stream reaches 84.7 GW undeveloped hydropower in undeveloped stream reaches hydropower in the PNW #12;Studies at both National

246

Glossary of Screen Labels for PARS II V1  

Broader source: Energy.gov (indexed) [DOE]

Glossary 1 Glossary 1 Glossary of Screen Labels for PARS II V1.0.0 Goal The primary goal of this glossary is to help PARS II end users understand the items of data that they are viewing or entering on their PARS II application screens. It does not provide technical information on the schema of the PARS II database. A separate PARS II Data Dictionary document is being provided for PARS II users who need such technical information. Overview This document consists of a table defining each data label displayed on PARS II screens. It is divided into sections by PARS II screen title. To find the meaning of a data item, first find the section describing the relevant screen, then find the particular screen label description. The sections are listed in order of the major functional area of the PARS II System:

247

GPU Computational Screening  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

GPU GPU Computational Screening of Carbon Capture Materials J. Kim 1 , A Koniges 1 , R. Martin 1 , M. Haranczyk 1 , J. Swisher 2 , and B. Smit 1,2 1 Lawrence Berkeley National Laboratory, Berkeley, CA 94720 2 Department of Chemical Engineering, University of California, Berkeley, Berkeley, CA 94720 E-mail: jihankim@lbl.gov Abstract. In order to reduce the current costs associated with carbon capture technologies, novel materials such as zeolites and metal-organic frameworks that are based on microporous networks are being studied. We have developed a GPU code that can characterize and screen a large database of zeolite structures and help identify the most e cient structures for carbon capture. The interactions between the atoms that constitute the zeolite structures and the gas molecules such as carbon dioxide and methane are described by the Lennard-Jones and Coulomb potentials.

248

Medical Screening | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Program Program Implementation » Medical Screening Medical Screening Medical Screening: Provide medical screening exams that are designed to check for health conditions related to occupational exposures to former workers who choose to participate in the program, including a re-screen exam every three years. Conventional Medical Screening Program Medical screening is a strategy used to identify diseases or conditions in a select population at an early stage, often before signs and symptoms develop, and to refer individuals with suspicious findings to their personal physician or a specialist for further testing, diagnosis, and treatment. The program is not intended to serve as a substitute for routine medical exams through an individual's personal physician. Early Lung Cancer Detection Program

249

Screen Electrode Materials & Cell Chemistries and Streamlining...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Screen Electrode Materials & Cell Chemistries and Streamlining Optimization of Electrode Screen Electrode Materials & Cell Chemistries and Streamlining Optimization of Electrode...

250

Dynamic Screening and Thermonuclear Reaction Rates  

E-Print Network [OSTI]

We show that there are no dynamic screening corrections to the Salpeter's enhancement factor in the weak-screening limit.

Andrei V. Gruzinov

1997-02-06T23:59:59.000Z

251

Precision and recall estimates for two-hybrid screens  

Science Journals Connector (OSTI)

......provides a superior fit. Analysis of protein interaction...for assessment of the reliability of high throughput observations...Eisenberg D , et al. Analysis of membrane and surface...high-density picolitre reactors. Nature (2005) 437...split-ubiquitin for the analysis of interactions between......

Hailiang Huang; Joel S. Bader

2009-02-01T23:59:59.000Z

252

Computational tools for high-throughput discovery in biology  

E-Print Network [OSTI]

Towards creating a compute power grid. Cluster Computing andfor all data processing: the power grid. With a well-frameddevelopers. Since this Power Grid analogy has more or less

Jones, Neil Christopher

2007-01-01T23:59:59.000Z

253

High-Throughput Detection of West Nile Virus RNA  

Science Journals Connector (OSTI)

...increased the amplification efficiency. However, we found...increase the amplification efficiency in assays targeting...Forster Zwischenmolekulare energy-wanderung und fluoreszenz...France . J. R. Lakowicz Energy transfer . R. S. Lanciotti...Isolation from human sera in Egypt of a virus apparently...

Pei-Yong Shi; Elizabeth B. Kauffman; Ping Ren; Andy Felton; Jennifer H. Tai; Alan P. Dupuis II; Susan A. Jones; Kiet A. Ngo; David C. Nicholas; Joseph Maffei; Gregory D. Ebel; Kristen A. Bernard; Laura D. Kramer

2001-04-01T23:59:59.000Z

254

High-Throughput Transfer Imprinting for Organic Semiconductors  

E-Print Network [OSTI]

focused infrared laser heats stamping layer(PMMA) up to glass transition temperature within very short time. And the pressure applied through the roller presses the flat mold and the pattern is imprinted on the PMMA layer. This method can imprint... with higher speed and achieved wider area of imprinting than conventional imprint method. [17] MOLD Substrate PMMA IR Roller Figure 8 Concept of roller imprinting based on focus infrared heating. 17 CHAPTER II PROBLEM STATEMENT...

Choo, Gihoon

2013-08-06T23:59:59.000Z

255

Computational tools for high-throughput discovery in biology  

E-Print Network [OSTI]

approach of a Service Oriented Architecture, where softwaredescribed as a service oriented architecture. Several ofWhile a Service Oriented Architecture (usually implemented

Jones, Neil Christopher

2007-01-01T23:59:59.000Z

256

High-throughput single-microparticle imaging flow analyzer  

Science Journals Connector (OSTI)

...using standard replica mold-ing methods (Fig. S1) (1). Our previously reported channels (2) were drawn in AutoCAD (Autodesk, Inc.). The design was printed as a photolithography transparency mask at 20,000 dots per inch (dpi). A negative photoresist...

Keisuke Goda; Ali Ayazi; Daniel R. Gossett; Jagannath Sadasivam; Cejo K. Lonappan; Elodie Sollier; Ali M. Fard; Soojung Claire Hur; Jost Adam; Coleman Murray; Chao Wang; Nora Brackbill; Dino Di Carlo; Bahram Jalali

2012-01-01T23:59:59.000Z

257

Erythrocyte deformation in high-throughput optical stretchers  

Science Journals Connector (OSTI)

Optical stretchers can be used to quantify elastic and homeostatic properties of cells. Because they can apply forces to cells without requiring direct contact, they may noninvasively measure mechanical properties related to cell and membrane health. Present-day optical stretchers are, however, limited to measurements on individual stationary cells, limiting throughput. To overcome this limitation and allow study of variations in cell populations, we recently developed and tested a microfluidic chamber that measures optical stretching parameters for erythrocytes under dynamic flowing conditions. The method uses a single linear diode laser bar and permitted measurements at low flow rates and higher throughput. Here, we numerically investigate the feasibility of further increasing the measurement rates of the optical stretcher in parameter domains where hydrodynamic and optical forces are of comparable magnitude. To do this we couple a recently implemented dynamic optical ray-tracing technique with a fluid-structure interaction solver to simulate the deformation of osmotically swollen erythrocytes in fluid flow of variable rate. Our results demonstrate that a detectable steady-state stretch is induced at nominal optical powers and flow rates. In addition, we find that flow rates can be increased significantly with no major effect on net cell stretch showing the feasibility of application of this technique at greatly increased throughputs.

Ihab Sraj; Alex C. Szatmary; Sanjay A. Desai; David W. M. Marr; Charles D. Eggleton

2012-04-30T23:59:59.000Z

258

Optical Multiplexing for High-Throughput Spectroscopic Analysis.  

E-Print Network [OSTI]

in optical biosensor testing as it provides greater throughput and scalability while being an economical and compact solution. v NOMENCLATURE MFPF Multi Frequency Phase Fluorometer MUX Multiplexer LED Light Emitting Diode DIO Digital Input... oxidase in hybrid silicate microsphere that is coated with nanofilm and reference dye (RITC) (Fig. 1) [2]. The phosphorescent dye is excited by a green light from a LED (light emitting diode) to emit luminescence, the intensity of which is dependent...

Ahmed, Saadiah

2012-05-03T23:59:59.000Z

259

Mixing in Unbaffled High-Throughput Experimentation Reactors  

Science Journals Connector (OSTI)

Use of unbaffled vessels is essential because of the automation of the unit responsible for loading, sampling, discharging, and cleaning the vessel; such tasks are easier for a robot to perform on unbaffled vessels because material can be trapped around baffle plates, especially when viscous materials are involved. ... The impellers were painted with matte black paint to prevent reflection of incident laser radiation and also to seal the impeller surface. ...

Jonathan F. Hall; Mostafa Barigou; Mark J. H. Simmons; E. Hugh Stitt

2004-06-09T23:59:59.000Z

260

Integrated microbioreactor arrays for high-throughput experimentation  

E-Print Network [OSTI]

Bioprocesses with microbial cells play an important role in producing biopharmaceuticals such as human insulin and human growth hormone, and other products such as amino acids and biopolymers. Because bioprocesses involve ...

Lee, Harry, 1976-

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Systematic reconstruction of RNA functional motifs with high throughput microfluidics  

E-Print Network [OSTI]

-quarters of the human genome is capable of being transcribed1. Because only ~1.5% of the genome encodes for protein, non specificities and enriches interpretation of phylogenetic data. The ENCODE project has shown that three-coding RNAs (ncRNAs) may be a highly abundant output of genetic information. ncRNAs can exert epigenetic

Quake, Stephen R.

262

Low inlet gas velocity high throughput biomass gasifier  

DOE Patents [OSTI]

The present invention discloses a novel method of operating a gasifier for production of fuel gas from carbonaceous fuels. The process disclosed enables operating in an entrained mode using inlet gas velocities of less than 7 feet per second, feedstock throughputs exceeding 4000 lbs/ft.sup.2 -hr, and pressures below 100 psia.

Feldmann, Herman F. (Worthington, OH); Paisley, Mark A. (Upper Arlington, OH)

1989-01-01T23:59:59.000Z

263

Operational streamlining in a high-throughput genome sequencing center  

E-Print Network [OSTI]

Advances in medicine rely on accurate data that is rapidly provided. It is therefore critical for the Genome Sequencing platform of the Broad Institute of MIT and Harvard to continually strive to reduce cost, improve ...

Person, Kerry P. (Kerry Patrick)

2006-01-01T23:59:59.000Z

264

METHODOLOGY Open Access High throughput quantitative phenotyping of  

E-Print Network [OSTI]

is not sensitive to environmental light variations and provides single-channel images prone to a segmentation Horticulture et Semences, Beaucouzé F-49071, France 2 UMR1345 Institut de Recherche en Horticulture et Semences

Paris-Sud XI, Université de

265

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

Broader source: Energy.gov (indexed) [DOE]

ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D Ned Stetson, Larry Blair 1 , Grace Ordaz, Carole Read, George Thomas 2 , and Sunita Satyapal Suite 900, 7475...

266

Vectorized AES core for high-throughput secure environments  

E-Print Network [OSTI]

`odul D6 Campus Nord, 08034 Barcelona, Spain Phone: +34 934 017 001, Fax: +34 934 017 055 mpericas the evaluation of an encryption core capable of handling multiple data streams. The de- sign is oriented towards cryptographic engines with multiple streams to better exploit the available bandwidth. Several specific cases

Kuzmanov, Georgi

267

Approaches and problems in high-throughput genotyping.  

Science Journals Connector (OSTI)

...probes; 4) DNA hybridization, e.g., microarrays, electronic DNA chips, molecular beacons, and dynamic allele-specific...Amplification. Beyond chemistries and platforms, one more fundamental thing to understand about SNP genotyping is the issue of...

Anthony J. Brookes

2004-04-01T23:59:59.000Z

268

Updating Technical Screens for PV Interconnection: Preprint  

SciTech Connect (OSTI)

Solar photovoltaics (PV) is the dominant type of distributed generation (DG) technology interconnected to electric distribution systems in the United States, and deployment of PV systems continues to increase rapidly. Considering the rapid growth and widespread deployment of PV systems in United States electric distribution grids, it is important that interconnection procedures be as streamlined as possible to avoid unnecessary interconnection studies, costs, and delays. Because many PV interconnection applications involve high penetration scenarios, the process needs to allow for a sufficiently rigorous technical evaluation to identify and address possible system impacts. Existing interconnection procedures are designed to balance the need for efficiency and technical rigor for all DG. However, there is an implicit expectation that those procedures will be updated over time in order to remain relevant with respect to evolving standards, technology, and practical experience. Modifications to interconnection screens and procedures must focus on maintaining or improving safety and reliability, as well as accurately allocating costs and improving expediency of the interconnection process. This paper evaluates the origins and usefulness of the capacity penetration screen, offers potential short-term solutions which could effectively allow fast-track interconnection to many PV system applications, and considers longer-term solutions for increasing PV deployment levels in a safe and reliable manner while reducing or eliminating the emphasis on the penetration screen.

Coddington, M.; Ellis, A.; Lynn, K.; Razon, A.; Key, T.; Kroposki, B.; Mather, B.; Hill, R.; Nicole, K.; Smith, J.

2012-08-01T23:59:59.000Z

269

Medical Screening | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

for routine medical exams through an individual's personal physician. Early Lung Cancer Detection Program Since 2000, DOE has made screening for occupational lung cancer with...

270

Impurity screening in carbon nanotubes  

Science Journals Connector (OSTI)

Nanotube geometry determines electronic structure and thus impurity screening. A metallic carbon nanotube could effectively screen a charged impurity, while a semiconducting carbon nanotube could not. The ability to screen a long-range Coulomb field is mainly determined by whether there are free carriers in the subbands nearest the Fermi level. The detailed screening properties are sensitive to the impurity position, and the tubular structure (such as radius and chiral angle). Strong, short-wavelength Friedel oscillations at long distances are found to exist only in metallic armchair nanotubes. They are relatively obvious for a smaller armchair nanotube, and could survive at room temperature.

M. F. Lin and D. S. Chuu

1997-08-15T23:59:59.000Z

271

Comments on Gaugino Screening  

SciTech Connect (OSTI)

Gauge mediated models of supersymmetry breaking often exhibit 'gaugino screening,' where to leading order in F, gaugino masses are unaffected by higher dimensional Kahler potential interactions between the supersymmetry breaking spurion and the messengers. We provide a derivation of this phenomenon which utilizes the gaugino counterterm originally proposed in the context of anomaly mediation by Dine and Seiberg. We argue that this counterterm is present when there are non-zero messenger F-terms, and can cancel the leading order Feynman diagram contribution to the gaugino mass. We provide a nontrivial check of the regulator independence of our results by performing the computation using both dimensional reduction and Pauli-Villars. This analysis reconciles an apparent contradiction between diagrammatics and analytic continuation into superspace.

Cohen, Timothy; Hook, Anson; Wecht, Brian

2012-02-15T23:59:59.000Z

272

Electron screening in nickel  

SciTech Connect (OSTI)

In order to further investigate electron screening phenomenon we studied proton induced nuclear reactions over an energy range from 1.35 to 3.08 MeV for different environments: Ni metal and NiO insulator. The measurements were based on observation of the {gamma}-ray yields of {sup 59,61,63,64,65}Cu and {sup 58,60,62}Ni. Also, we have studied the decay of {sup 61}Cu produced in the reaction {sup 60}Ni(p,{gamma}), in order to find a possible decay rate perturbation by atomic electrons and found a small difference in half-life for metallic compared to oxide environment, respectively. The present results clearly show that the metallic environment affects the fusion reactions at low energy and that it might also affect the decay rate.

Gajevic, Jelena; Lipoglavsek, Matej; Petrovic, Toni; Pelicon, Primoz [Jozef Stefan Institute, Jamova cesta 39, Ljubljana (Slovenia); Jozef Stefan Institute, Jamova cesta 39, Ljubljana (Slovenia) and Cosylab d.d, Teslova ulica 30, Ljubljana (Slovenia); Jozef Stefan Institute, Jamova cesta 39, Ljubljana (Slovenia)

2012-11-20T23:59:59.000Z

273

Development of a receptor model for efficient in silico screening of HIV-1 integrase inhibitors  

Science Journals Connector (OSTI)

Abstract Integrase (IN) is a key viral enzyme for the replication of the type-1 human immunodeficiency virus (HIV-1), and as such constitutes a relevant therapeutic target for the development of anti-HIV agents. However, the lack of crystallographic data of HIV IN complexed with the corresponding viral DNA has historically hindered the application of modern structure-based drug design techniques to the discovery of new potent IN inhibitors (INIs). Consequently, the development and validation of reliable HIV IN structural models that may be useful for the screening of large databases of chemical compounds is of particular interest. In this study, four HIV-1 IN homology models were evaluated respect to their capability to predict the inhibition potency of a training set comprising 36 previously reported \\{INIs\\} with IC50 values in the low nanomolar to the high micromolar range. Also, 9 inactive structurally related compounds were included in this training set. In addition, a crystallographic structure of the IN-DNA complex corresponding to the prototype foamy virus (PFV) was also evaluated as structural model for the screening of inhibitors. The applicability of high throughput screening techniques, such as blind and ligand-guided exhaustive rigid docking was assessed. The receptor models were also refined by molecular dynamics and clustering techniques to assess protein sidechain flexibility and solvent effect on inhibitor binding. Among the studied models, we conclude that the one derived from the X-ray structure of the PFV integrase exhibited the best performance to rank the potencies of the compounds in the training set, with the predictive power being further improved by explicitly modeling five water molecules within the catalytic side of IN. Also, accounting for protein sidechain flexibility enhanced the prediction of inhibition potencies among the studied compounds. Finally, an interaction fingerprint pattern was established for the fast identification of potent IN inhibitors. In conclusion, we report an exhaustively validated receptor model if IN that is useful for the efficient screening of large chemical compounds databases in the search of potent HIV-1 IN inhibitors.

Mario A. Quevedo; Sergio R. Ribone; Margarita C. Brin; Wim Dehaen

2014-01-01T23:59:59.000Z

274

Preliminary Screening | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Preliminary Screening Preliminary Screening Preliminary Screening October 16, 2013 - 5:12pm Addthis The first step in assessing renewable energy options is to conduct a preliminary screening to decide which technologies are worth investigating and which can be eliminated immediately. Preliminary screening involves using resource maps and other basic tools to choose technologies to pursue further. This should occur in the planning phase and can be completed at the agency level with some simple training. There should be no need to hire an outside consultant at this stage. When narrowing technology options during this phase of assessment, a range of factors are considered, such as: Available Renewable Resources Ability to Connect to the Grid Available Renewable Resources Renewable energy resources refer to the amount of energy that can be

275

Personal Navigation Increases Colorectal Cancer Screening Uptake  

Science Journals Connector (OSTI)

...the participants' preferred screening test (colonoscopy or stool blood testing...and no record of a recent CRC screening test were identified at the Group Health Centre...performance of the preferred screening test. Multivariate analyses were conducted...

Paul G. Ritvo; Ronald E. Myers; Lawrence F. Paszat; Jill M. Tinmouth; Joshua McColeman; Brian Mitchell; Mardie Serenity; Linda Rabeneck

276

DOD - Preliminary Screening Tool | Open Energy Information  

Open Energy Info (EERE)

Screening Tool Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: DOD - Preliminary Screening Tool Abstract This webpage contains the DOD preliminary...

277

Screening of quark-monopole in N=4 plasma  

E-Print Network [OSTI]

We study a quark-monopole bound system moving in N=4 SYM plasma with a constant velocity by the AdS/CFT correspondence. The screening length of this system is calculated, and is smaller than that of the quark-antiquark bound state.

Wei-shui Xu; Ding-fang Zeng

2014-09-08T23:59:59.000Z

278

Document Control Template-Instruction_Screen Shot  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 1 of 6 3_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 1 of 6 EOTA - Business Instruction Document Title: Document Control Template - Instruction-Screen Shot Document Number: F-003 Rev. A Document Owner: Elizabeth Sousa Backup Owner: Melissa Otero Approver(s): Melissa Otero Parent Document: P-001, Document Control Process Notify of Changes: EOTA Employees Referenced Document(s): N/A F-003_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 2 of 6 Revision History: Rev. Description of Change A Initial Release B C D E F-003_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 3 of 6 EOTA - Business Instruction Document Title: DocTitle Document Number:

279

Walla Walla River Basin Fish Screens Evaluations, 2006 Annual Report.  

SciTech Connect (OSTI)

Pacific Northwest National Laboratory evaluated Gardena Farms, Little Walla Walla, and Garden City/Lowden II Phase II fish screen facilities and provided underwater videography beneath a leaking rubber dam in the Walla Walla River basin in 2006. Evaluations of the fish screen facilities took place in early May 2006, when juvenile salmonids are generally outmigrating. At the Gardena Farms site, extended high river levels caused accumulations of debris and sediment in the forebay. This debris covered parts of the bottom drum seals, which could lead to early deterioration of the seals and drum screen. Approach velocities were excessive at the upstream corners of most of the drums, leading to 14% of the total approach velocities exceeding 0.4 feet per second (ft/s). Consequently, the approach velocities did not meet National Marine Fisheries Service (NMFS) design criteria guidelines for juvenile fish screens. The Little Walla Walla site was found to be in good condition, with all approach, sweep, and bypass velocities within NMFS criteria. Sediment buildup was minor and did not affect the effectiveness of the screens. At Garden City/Lowden II, 94% of approach velocities met NMFS criteria of 0.4 ft/s at any time. Sweep velocities increased toward the fish ladder. The air-burst mechanism appears to keep large debris off the screens, although it does not prevent algae and periphyton from growing on the screen face, especially near the bottom of the screens. In August 2006, the Gardena Farm Irrigation District personnel requested that we look for a leak beneath the inflatable rubber dam at the Garden City/Lowden II site that was preventing water movement through the fish ladder. Using our underwater video equipment, we were able to find a gap in the sheet piling beneath the dam. Erosion of the riverbed was occurring around this gap, allowing water and cobbles to move beneath the dam. The construction engineers and irrigation district staff were able to use the video footage to resolve the problem within a couple weeks. We had hoped to also evaluate the effectiveness of modifications to louvers behind the Nursery Bridge screens when flows were higher than 350 cubic feet per second, (cfs) but were unable to do so. Based on the one measurement made in early 2006 after the modified louvers were set, it appears the modified louvers may help reduce approach velocities. The auxiliary supply water system gates also control water through the screens. Evaluating the effect of different combinations of gate and louver positions on approach velocities through the screens may help identify optimum settings for both at different river discharges.

Chamness, Mickie; Abernethy, Scott; Tunnicliffe, Cherylyn [Pacific Northwest National Laboratory

2007-01-01T23:59:59.000Z

280

Screening Pumping Systems for Energy Savings Opportunities  

E-Print Network [OSTI]

for Operating parameters: Operating traction ~h.ooo II Electric power, kWe I 154.0 II 151.5 II 108.2 I background information Electricily cost cents/kwhr ~15.40 'I' Annual energy, MWhr ) 1349.0 II 1327.3 II 947.41 Measured or required conditions: . Annual... for Operating parameters: Operating traction ~h.ooo II Electric power, kWe I 154.0 II 151.5 II 108.2 I background information Electricily cost cents/kwhr ~15.40 'I' Annual energy, MWhr ) 1349.0 II 1327.3 II 947.41 Measured or required conditions: . Annual...

Casada, D.

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Dynamical screening in bilayer graphene  

Science Journals Connector (OSTI)

We calculate one-loop polarization in bilayer graphene in the four-band approximation for arbitrary values of frequency, momentum, and doping. At low and high energy our results reduce to the polarization functions calculated in the two-band approximation and in the case of single-layer graphene, respectively. The special cases of static screening and plasmon modes are analyzed.

O. V. Gamayun

2011-08-22T23:59:59.000Z

282

Chemical compatibility screening test results  

SciTech Connect (OSTI)

A program for evaluating packaging components that may be used in transporting mixed-waste forms has been developed and the first phase has been completed. This effort involved the screening of ten plastic materials in four simulant mixed-waste types. These plastics were butadiene-acrylonitrile copolymer rubber, cross-linked polyethylene (XLPE), epichlorohydrin rubber, ethylene-propylene rubber (EPDM), fluorocarbon (Viton or Kel-F), polytetrafluoroethylene, high-density polyethylene (HDPE), isobutylene-isoprene copolymer rubber (butyl), polypropylene, and styrene-butadiene rubber (SBR). The selected simulant mixed wastes were (1) an aqueous alkaline mixture of sodium nitrate and sodium nitrite; (2) a chlorinated hydrocarbon mixture; (3) a simulant liquid scintillation fluid; and (4) a mixture of ketones. The testing protocol involved exposing the respective materials to 286,000 rads of gamma radiation followed by 14-day exposures to the waste types at 60{degrees}C. The seal materials were tested using vapor transport rate (VTR) measurements while the liner materials were tested using specific gravity as a metric. For these tests, a screening criterion of 0.9 g/hr/m{sup 2} for VTR and a specific gravity change of 10% was used. Based on this work, it was concluded that while all seal materials passed exposure to the aqueous simulant mixed waste, EPDM and SBR had the lowest VTRs. In the chlorinated hydrocarbon simulant mixed waste, only Viton passed the screening tests. In both the simulant scintillation fluid mixed waste and the ketone mixture simulant mixed waste, none of the seal materials met the screening criteria. For specific gravity testing of liner materials, the data showed that while all materials with the exception of polypropylene passed the screening criteria, Kel-F, HDPE, and XLPE offered the greatest resistance to the combination of radiation and chemicals.

Nigrey, P.J.; Dickens, T.G.

1997-12-01T23:59:59.000Z

283

DOE: Former Worker Medical Screening Program (FWP)  

Broader source: Energy.gov [DOE]

FWP provides no-cost medical screenings to all former DOE Federal, contractor and subcontractor employees. The screening exams are offered by third party providers from universities, labor unions,...

284

Generalized charge-screening in relativistic ThomasFermi model  

SciTech Connect (OSTI)

In this paper, we study the charge shielding within the relativistic Thomas-Fermi model for a wide range of electron number-densities and the atomic-number of screened ions. A generalized energy-density relation is obtained using the force-balance equation and taking into account the Chandrasekhar's relativistic electron degeneracy pressure. By numerically solving a second-order nonlinear differential equation, the Thomas-Fermi screening length is investigated, and the results are compared for three distinct regimes of the solid-density, warm-dense-matter, and white-dwarfs (WDs). It is revealed that our nonlinear screening theory is compatible with the exponentially decaying Thomas-Fermi-type shielding predicted by the linear response theory. Moreover, the variation of relative Thomas-Fermi screening length shows that extremely dense quantum electron fluids are relatively poor charge shielders. Calculation of the total number of screening electrons around a nucleus shows that there is a position of maximum number of screening localized electrons around the screened nucleus, which moves closer to the point-like nucleus by increase in the plasma number density but is unaffected due to increase in the atomic-number value. It is discovered that the total number of screening electrons, (N{sub s}?r{sub TF}{sup 3}/r{sub d}{sup 3} where r{sub TF} and r{sub d} are the Thomas-Fermi and interparticle distance, respectively) has a distinct limit for extremely dense plasmas such as WD-cores and neutron star crusts, which is unique for all given values of the atomic-number. This is equal to saying that in an ultrarelativistic degeneracy limit of electron-ion plasma, the screening length couples with the system dimensionality and the plasma becomes spherically self-similar. Current analysis can provide useful information on the effects of relativistic correction to the charge screening for a wide range of plasma density, such as the inertial-confined plasmas and compact stellar objects.

Akbari-Moghanjoughi, M. [Department of Physics, Faculty of Sciences, Azarbaijan Shahid Madani University, 51745-406 Tabriz, Iran and International Centre for Advanced Studies in Physical Sciences and Institute for Theoretical Physics, Ruhr University Bochum, D-44780 Bochum (Germany)

2014-10-15T23:59:59.000Z

285

MR SCREENING FORM FOR RESEARCH STAFF Page 1 of 2  

E-Print Network [OSTI]

MR SCREENING FORM FOR RESEARCH STAFF Page 1 of 2 (PLEASE PRINT) NAME DATE: Before entering the MR environment or MR system room, you must remove all metallic objects including hearing aids, dentures, partial may be advised or required to wear earplugs or other hearing protection during the MR procedure

286

Euclid, NERSC's Sunfire Shared Memory Analytics System  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

High Throughput Job Carver seriallong queue, or Hopper Hight Throughput Queue Large Memory Batch MPP Code Carver Extra-large memory noderegxlmem queue Large Memory Interactive...

287

An Empirical Study on the Smallest Comfortable Button/Icon Size on Touch Screen  

Science Journals Connector (OSTI)

For the convenience of firefighters decision-making and operation, touch screen display was chosen as the preferred interface for a fire information display system. Few studies were conducted to determine comfor...

Xianghong Sun; Tom Plocher; Weina Qu

2007-01-01T23:59:59.000Z

288

Conventional Medical Screening Program | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Conventional Medical Screening Program Conventional Medical Screening Program Conventional Medical Screening Program Medical screening is a strategy used to identify diseases or conditions in a select population at an early stage, often before signs and symptoms develop, and to refer individuals with suspicious findings to their personal physician or a specialist for further testing, diagnosis, and treatment. The program is not intended to serve as a substitute for routine medical exams through an individual's personal physician. The medical screening exam offered by the FWP evaluates an employee's health as it relates to their potential occupational exposures to hazardous agents. The FWP uses a customized medical screening protocol that was developed by a team of independent physicians specializing in occupational

289

Reverberatory screen for a radiant burner  

DOE Patents [OSTI]

The present invention relates to porous mat gas fired radiant burner panels utilizing improved reverberatory screens. The purpose of these screens is to boost the overall radiant output of the burner relative to a burner using no screen and the same fuel-air flow rates. In one embodiment, the reverberatory screen is fabricated from ceramic composite material, which can withstand higher operating temperatures than its metallic equivalent. In another embodiment the reverberatory screen is corrugated. The corrugations add stiffness which helps to resist creep and thermally induced distortions due to temperature or thermal expansion coefficient differences. As an added benefit, it has been unexpectedly discovered that the corrugations further increase the radiant efficiency of the burner. In a preferred embodiment, the reverberatory screen is both corrugated and made from ceramic composite material.

Gray, Paul E. (North East, MD)

1999-01-01T23:59:59.000Z

290

Amchitka Former Workers, Construction Worker Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Amchitka Former Workers, Construction Worker Screening Projects Amchitka Former Workers, Construction Worker Screening Projects Amchitka Former Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Amchitka Worker Population Served: All workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

291

Screening masses in thermal and dense medium  

E-Print Network [OSTI]

Screening masses of different hadronic states are studied in thermal and dense medium on lattice. It has been found that screening masses increase with the temperature. In deconfinement phase, chemical potential enhances the screening masses. We use the normalization with respect to lowest Matsubara frequency to characterize dissolving of hadronic bound states at high temperatures. It has been found that different hadronic states have different dissolving temperatures and their survivals are considerably improved at finite chemical potentials.

A. Tawfik

2006-05-29T23:59:59.000Z

292

Improving Screening Strategies for Prostate Cancer.  

E-Print Network [OSTI]

??abstractTh is thesis describes research on screening for prostate cancer. To improve understanding of the thesis, some background information will be provided in this introduction. (more)

T. Wolters (Tineke)

2010-01-01T23:59:59.000Z

293

Information, Planning, and Conservation (IPAC) online screening...  

Open Energy Info (EERE)

Information, Planning, and Conservation (IPAC) online screening tool Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- OtherOther: Information,...

294

Beryllium Vender Screening Program | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

through DOL's EEOICP. Former workers interested in medical screening can contact the Oak Ridge Institute of Science and Education at 1-866-219-3442. DOE beryllium vendor...

295

Phase Behavior of Pseudobinary Precious Metal?Carbide Systems  

SciTech Connect (OSTI)

Transition metal carbides exhibit a variety of interesting material properties, including electrochemical stability. When combined with precious metals, Ta and W carbides have shown promise as fuel cell electrode materials; yet, the phase behavior of these precious metal?carbide systems is largely unexplored. We investigated P-M-C phase behavior with P = Pt, Pd, and Ru and M = Ta and W using composition spread thin films. We attained limited control of the deposited carbide phase through variation of the sputter atmosphere and demonstrated decreased corrosion of W?C materials with increasing C content. A high-throughput X-ray diffraction and X-ray fluorescence experiment was employed for thin film characterization, which revealed solubility of Pt, Pd, and Ru in cubic WC. Density functional calculations of the lattice parameter dependence on carbon concentration enabled the determination of carbon concentration from the X-ray data as a function of transition metal stoichiometry. Our measurement of variations in the C stoichiometry and evolution of thin film texture with transition metal composition yielded surprising results. We detail how the combination of the composition spread technique, the high-throughput thin film characterization, and the density functional modeling of ternary carbide alloys provided a deep understanding of the chemical systems.

Gregoire, John M.; Tague, Michele E.; Smith, Eva H.; Dale, Darren; DiSalvo, Francis J.; Abrua, Hctor D.; Hennig, Richard G.; van Dover, R. Bruce

2010-01-01T23:59:59.000Z

296

Screening in gated bilayer graphene  

Science Journals Connector (OSTI)

The tight-binding model of a graphene bilayer is used to find the gap between the conduction and valence bands, as a function of both the gate voltage and as the doping by donors or acceptors. The total Hartree energy is minimized and the equation for the gap is obtained. This equation for the ratio of the gap to the chemical potential is determined only by the screening constant. Thus the gap is strictly proportional to the gate voltage or the carrier concentration in the absence of donors or acceptors. In the opposite case, where the donors or acceptors are present, the gap demonstrates the asymmetrical behavior on the electron and hole sides of the gate bias.

L. A. Falkovsky

2009-09-30T23:59:59.000Z

297

Fusion Protein Products Screen Purify Detect Cleave  

E-Print Network [OSTI]

Fusion Protein Products · Screen · Purify · Detect · Cleave Fusion Protein Products · Screen researchers look to plasmid vectors to express fusion proteins, they find themselves in need of methods proteins is also included for those fusion proteins that may have an inaccessible tag. Pierce offers a host

Lebendiker, Mario

298

Beryllium Vender Screening Program | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Worker » Former Worker Program » Beryllium Worker » Former Worker Program » Beryllium Vender Screening Program Beryllium Vender Screening Program In February 2005, DOE expanded the beryllium screening program to include former employees of defunct DOE beryllium vendors who were employed with these companies while they performed work for DOE. This change was made to ensure that workers who no longer have an employer to turn to for beryllium disease testing could receive this important screening. DOE will offer these individuals a blood test at no cost to check for beryllium sensitization. DOE will pay for both the costs of drawing the blood and the analysis of the blood. If a screened individual receives an abnormal test for beryllium sensitization, they can receive medical monitoring for beryllium disease

299

Proximal surface caries detection with direct-exposure and rare earth screen/film imaging  

SciTech Connect (OSTI)

This laboratory study compared five imaging systems for their diagnostic accuracy in detection of proximal surface dental caries. Ten viewers provided data on radiographic detectability of carious lesions. The diagnostic accuracy of each system was determined with receiver operating characteristic (ROC) curves by comparing viewer data with the true state of the teeth as determined microscopically. D-speed film marginally outperformed the other four systems, but the three screen/film systems matched the diagnostic accuracy of E-speed film. Radiation reductions between 62% and 92% were achieved with the screen/film systems when compared to the two conventional dental films. The feasibility of designing a screen/film bite-wing cassette was shown, but the poor diagnostic accuracy of the present bite-wing system indicated a need for a new technology in caries detection.

Lundeen, R.C.; McDavid, W.D.; Barnwell, G.M.

1988-12-01T23:59:59.000Z

300

Pre-Screening for Solar Projects on Federal Sites | Department...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Pre-Screening for Solar Projects on Federal Sites Pre-Screening for Solar Projects on Federal Sites Photo of a solar array. Conducting an agency-wide solar energy pre-screening is...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Spatially Resolved Seebeck Coefficient Measurements  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

in new materials (holeselectrons) and can do high-throughput screening of optoelectronic and thermoelectric materials. Research Details Design Feature: Steady-state...

302

E-Print Network 3.0 - anti-arrhythmic anti-hypertensiveanti...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Chemistry & High-Throughput Screening., in press Summary: on the reductive amination and Ugi reactions using as queries a known anti-arrhythmic agent and a product inhibitor...

303

Production Worker Screening Projects | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Production Production Worker Screening Projects Production Worker Screening Projects Sites listed below are the primary DOE sites served. Production workers from DOE sites not listed below are covered by the National Supplemental Screening Program (NSSP). Additional information regarding NSSP can be found on their website or by calling 1-866-812-6703. California: Lawrence Berkeley National Laboratory Lawrence Livermore National Laboratory Sandia National Laboratories (Livermore, CA) Colorado: Rocky Flats Florida: Pinellas Idaho: Argonne National Laboratory-West Idaho National Laboratory Illinois: Argonne National Laboratory Fermi National Accelerator Laboratory Iowa: Ames Laboratory Iowa Army Ammunition Plant Kentucky: Paducah Gaseous Diffusion Plant Missouri: Kansas City Plant Nevada:

304

Construction Worker Screening Projects | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Worker » Former Worker Program » Worker » Former Worker Program » Construction Worker Screening Projects Construction Worker Screening Projects Sites listed below are the primary DOE sites served. Construction workers from DOE sites not listed below are covered by the Building Trades National Medical Screening Program (BTMed). Additional information regarding BTMed can be found on their website or by calling 1-800-866-9663. Alaska: Amchitka California: Lawrence Berkeley National Laboratory Lawrence Livermore National Laboratory Sandia National Laboratories (Livermore, CA) Colorado: Rocky Flats Florida: Pinellas Idaho: Argonne National Laboratory-West Idaho National Laboratory Illinois: Argonne National Laboratory Fermi National Accelerator Laboratory Iowa: Ames Laboratory Iowa Army Ammunition Plant

305

Renewable Energy Screening for All ESPCs | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Renewable Energy Screening for All ESPCs Renewable Energy Screening for All ESPCs Document helps Federal agencies provide data national laboratories need to conduct prescreening...

306

Korea's Thyroid-Cancer Epidemic Screening and Overdiagnosis  

Science Journals Connector (OSTI)

The Republic of Korea has provided national health insurance to its 50 million citizens since the 1980s. Although health care expenditures in South Korea's single-payer system are relatively low accounting for 7.6% of the country's gross domestic product the system is technologically intensive... In 2011, the rate of thyroid-cancer diagnoses in the Republic of Korea was 15 times that observed in 1993, yet thyroid-cancer mortality remains stable a combination that suggests that the problem is overdiagnosis attributable to widespread thyroid-cancer screening.

Ahn H.S.Kim H.J.Welch H.G.

2014-11-06T23:59:59.000Z

307

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline  

Science Journals Connector (OSTI)

Automated data collection for macromolecular crystallography at beamlines with protocols for automatic instrumentation improves the efficient use of available beamtime. These developments were a result of a collaboration between the main partners of SPINE and members of other similar European and national initiatives.

Beteva, A.

2006-09-19T23:59:59.000Z

308

Agency-Wide Screening | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Agency-Wide Screening Agency-Wide Screening Agency-Wide Screening October 16, 2013 - 4:36pm Addthis Federal agencies face energy-related requirements on new construction projects and major renovations. These Federal requirements range from reductions in fossil-fuel use to specifying the use of certain renewable energy technologies. As some agencies have already found out, not all sites or construction projects are created equal. Because many of the requirements are agency-wide, an effective and efficient way to meet these requirements is to consider and identify appropriate locations for these technologies across all agency land and building assets. FEMP can help Federal agencies conduct a renewable energy screening at all of its sites, or just at all of its upcoming construction project

309

Former Worker Medical Screening Program Brochure  

Broader source: Energy.gov [DOE]

The FWP brochure provides important information to inform former and current DOE Federal, contractor, and subcontractor employees about the benefits and services offered under the DOE Former Worker Medical Screening Program.

310

Preventive Health Screenings | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

leave year Preventive Health Screenings Responsible Contacts Bruce Murray HR Policy Advisor E-mail bruce.murray@hq.doe.gov Phone 202-586-3372 More Documents & Publications DOE...

311

Laser perforation of screen vacuum thermal insulation  

Science Journals Connector (OSTI)

This paper presents the results of the process of laser perforation of screen vacuum thermal insulation and shows that it has high efficiency. The use of various types of IR lasers...

Sysoev, V K; Vyatlev, P A; Zakharchenko, A V

2007-01-01T23:59:59.000Z

312

Screening citrus rootstocks for alkalinity tolerance  

E-Print Network [OSTI]

SCREENING CITRUS ROOTSTOCKS FOR ALKALINITY TOLERANCE A Thesis by SUDAHONO Submitted to the Office of Graduate Studies of Texas ALM University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE August 1991 Major... Subject: Horticulture SCREENING CITRUS ROOTSTOCKS FOR ALKALINITY TOLERANCE A Thesis by SUDAHONO Approved as to style and content by: David H. yr (Chair of Com ttee) Robert E. Rouse (Member) ~. Err. tg~i ~PI. ~~ Frank M. Hone (Member) Calvin G...

Sudahono

2012-06-07T23:59:59.000Z

313

Screening of a hypercritical charge in graphene  

Science Journals Connector (OSTI)

Screening of a large external charge in graphene is studied. The charge is assumed to be displaced away or smeared over a finite region of the graphene plane. The initial decay of the screened potential with distance is shown to follow the 3?2 power. It gradually changes to the Coulomb law outside of a hypercritical core whose radius is proportional to the external charge.

M. M. Fogler; D. S. Novikov; B. I. Shklovskii

2007-12-05T23:59:59.000Z

314

Cost-Effectiveness of CT Screening in the National Lung Screening Trial  

Science Journals Connector (OSTI)

Lung cancer is the leading cause of cancer-related deaths in the United States; however, until recently, no method of screening had been shown to reduce mortality from lung cancer. The National Lung Screening Trial (NLST) showed that screening with low-dose helical computed tomography (CT) of the... The screening of persons at risk for lung cancer may reduce lung-cancer mortality by 20%. Although cost-effectiveness estimates vary widely depending on assumptions, a careful analysis indicates that the cost is $81,000 per quality-adjusted life-year.

Black W.C.; Gareen I.F.; Soneji S.S.

2014-11-06T23:59:59.000Z

315

Species for the screening assessment. Columbia River Comprehensive Impact Assessment  

SciTech Connect (OSTI)

Because of past nuclear production operations along the Columbia River, there is intense public and tribal interest in assessing any residual Hanford Site related contamination along the river from the Hanford Reach to the Pacific Ocean. The Columbia River Comprehensive Impact Assessment was proposed to address these concerns. The assessment of the Columbia River is being conducted in phases. The initial phase is a screening assessment of the risk, which addresses current environmental conditions for a range of potential uses. One component of the screening assessment estimates the risk from contaminants in the Columbia River to the environment. The objective of the ecological risk assessment is to determine whether contaminants from the Columbia River pose a significant threat to selected receptor species that exist in the river and riparian communities of the study area. This report (1) identifies the receptor species selected for the screening assessment of ecological risk and (2) describes the selection process. The species selection process consisted of two tiers. In Tier 1, a master species list was developed that included many plant and animal species known to occur in the aquatic and riparian systems of the Columbia River between Priest Rapids Dam and the Columbia River estuary. This master list was reduced to 368 species that occur in the study area (Priest Rapids Dam to McNary Dam). In Tier 2, the 181 Tier 1 species were qualitatively ranked based on a scoring of their potential exposure and sensitivity to contaminants using a conceptual exposure model for the study area.

Becker, J.M.; Brandt, C.A.; Dauble, D.D.; Maughan, A.D.; O`Neil, T.K.

1996-03-01T23:59:59.000Z

316

Ecological Screening Values for Surface Water, Sediment, and Soil  

SciTech Connect (OSTI)

This document provides a comprehensive listing of ecological screening values for surface water, sediment, and soil.

Friday, G. P.

1999-03-15T23:59:59.000Z

317

HUD CHP GUIDE #2- FEASIBILITY SCREENING FOR CHP IN MULTIFAMILY HOUSING, May 2009  

Broader source: Energy.gov [DOE]

Guide shows the screens for the feasibility screening tool, computer software prepared for HUD by ORNL

318

Steady-State Screening-Photovoltaic Spatial Solitons in the  

Science Journals Connector (OSTI)

The theory of the screening-photovoltaic solitons is improved in biased photorefractive-photovoltaic crystals. When the photovoltaic effect is negligible, the screening-photovoltaic solitons are the screening ones, and their space-charge field is the space-charge field of the screening solitons. If the external field is absent, the screening-photovoltaic solitons are the photovoltaic ones on the open- and closed-circuit conditions, and their space-charge field is of the photovoltaic solitons. We also show theoretically that the screening and the photovoltaic solitons on the open- and closed-circuit conditions may be studies together as the screening-photovoltaic solitons.

Lu Ke-Qing; Zhang Yan-Peng; Tang Tian-Tong; Lu Zhi-Xian; Liu Lin

2001-01-01T23:59:59.000Z

319

Pooled ORF Expression Technology (POET) USING PROTEOMICS TO SCREEN POOLS OF OPEN READING FRAMES FOR PROTEIN EXPRESSION*S  

E-Print Network [OSTI]

are greatly simplified. Small scale expression and purification of 12 positive clones identified by POET from as much protein as 12 negative clones. Larger scale expression and purification of six of the positive attempted (4). In the standard approach to high throughput protein ex- pression and purification used

320

CHEMICAL SENSOR AND FIELD SCREENING TECHNOLOGY DEVELOPMENT: FUELS IN SOILS FIELD SCREENING METHOD VALIDATION  

SciTech Connect (OSTI)

A new screening method for fuel contamination in soils was recently developed as American Society for Testing and Materials (ASTM) Method D-583 1-95, Standard Test Method for Screening Fuels in Soils. This method uses low-toxicity chemicals and can be used to screen organic-rich soils. In addition, it is fast, easy, and inexpensive to perform. The screening method calls for extracting a sample of soil with isopropyl alcohol following treatment with calcium oxide. The resulting extract is filtered, and the ultraviolet absorbance of the extract is measured at 254 nm. Depending on the available information concerning the contaminant fuel type and availability of the contaminant fuel for calibration, the method can be used to determine the approximate concentration of fuel contamination, an estimated value of fuel contamination, or an indication of the presence or absence of fuel contamination. Fuels containing aromatic compounds, such as diesel fuel and gasoline, as well as other aromatic-containing hydrocarbon materials, such as motor oil, crude oil, and coal oil, can be determined. The screening method for fuels in soils was evaluated by conducting a collaborative study on the method and by using the method to screen soil samples at an actual field site. In the collaborative study, a sand and an organic soil spiked with various concentrations of diesel fuel were tested. Data from the collaborative study were used to determine the reproducibility (between participants) and repeatability (within participant) precision of the method for screening the test materials. The collaborative study data also provide information on the performance of portable field equipment versus laboratory equipment for performing the screening method and a comparison of diesel concentration values determined using the screening method versus a laboratory method. Data generated using the method to screen soil samples in the field provide information on the performance of the method in atypical real-world application.

Susan S. Sorini; John F. Schabron

1997-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Dainippon Screen Mfg Co | Open Energy Information  

Open Energy Info (EERE)

Dainippon Screen Mfg Co Dainippon Screen Mfg Co Jump to: navigation, search Name Dainippon Screen Mfg Co Place Kyoto, Kyoto, Japan Sector Solar Product Japan-based company engaged in the manufacture and sale of electronic equipment and image information processing and solar PV product production equipment Coordinates 35.098129°, 135.718933° Loading map... {"minzoom":false,"mappingservice":"googlemaps3","type":"ROADMAP","zoom":14,"types":["ROADMAP","SATELLITE","HYBRID","TERRAIN"],"geoservice":"google","maxzoom":false,"width":"600px","height":"350px","centre":false,"title":"","label":"","icon":"","visitedicon":"","lines":[],"polygons":[],"circles":[],"rectangles":[],"copycoords":false,"static":false,"wmsoverlay":"","layers":[],"controls":["pan","zoom","type","scale","streetview"],"zoomstyle":"DEFAULT","typestyle":"DEFAULT","autoinfowindows":false,"kml":[],"gkml":[],"fusiontables":[],"resizable":false,"tilt":0,"kmlrezoom":false,"poi":true,"imageoverlays":[],"markercluster":false,"searchmarkers":"","locations":[{"text":"","title":"","link":null,"lat":35.098129,"lon":135.718933,"alt":0,"address":"","icon":"","group":"","inlineLabel":"","visitedicon":""}]}

322

RENEWABLE ENERGY SCREENING FOR ALL ESPCs  

Broader source: Energy.gov (indexed) [DOE]

RENEWABLE ENERGY SCREENING FOR ALL ESPCs RENEWABLE ENERGY SCREENING FOR ALL ESPCs The Department of Energy's (DOE) Federal Energy Management Program (FEMP) Energy Savings Performance Contracts (ESPC) program has funded DOE National Laboratories to support agencies with increasing use of renewable energy technologies required per EPACT 2005 and Executive Order 13423. To utilize the no-cost support, the National Laboratories require some easily accessible high-level site and related energy data to conduct pre- screening analysis. The objective is to identify the economic feasibility of renewable technologies - wind, solar, and biomass power generation applications - that could be considered as Energy Conservation Measures (ECMs) in your ESPC. The National Laboratories commit to turning around

323

Screening Cargo Containers to Remove a Terrorist Threat  

SciTech Connect (OSTI)

Each year some 48 million cargo containers move between the world's ports. More than 6 million of these enter the U.S., but only about 2 percent are opened and inspected when they arrive at U.S. seaports. The West Coast ports of Los Angeles-Long Beach, Oakland, and Seattle alone process 11,000 containers per day, or about 8 containers per minute. Because of this high traffic volume, U.S. seaports are especially vulnerable to a terrorist attack. Illicit radioactive materials could be hidden in any one of the cargo-filled containers that arrive at U.S. ports. Yet, searching every shipment would be bring legitimate commercial activities to a halt. Improving security at U.S. ports is thus one of the nation's most difficult technical and practical challenges because the systems developed for screening cargo must operate in concert with ongoing seaport activities. Working at this intersection of commerce and national security, Lawrence Livermore researchers are applying their expertise in radiation science and detection to develop improved technologies for detecting hidden radioactive materials. One new technology being designed and tested at the Laboratory is a neutron interrogation system for cargo containers. This system will quickly screen incoming shipments to ensure that nuclear materials such as plutonium and highly enriched uranium (HEU) are not smuggled into the U.S.

Hazi, A

2005-09-20T23:59:59.000Z

324

Water Velocity Measurements on a Vertical Barrier Screen at the Bonneville Dam Second Powerhouse  

SciTech Connect (OSTI)

Fish screens at hydroelectric dams help to protect rearing and migrating fish by preventing them from passing through the turbines and directing them towards the bypass channels by providing a sweeping flow parallel to the screen. However, fish screens may actually be harmful to fish if they become impinged on the surface of the screen or become disoriented due to poor flow conditions near the screen. Recent modifications to the vertical barrier screens (VBS) at the Bonneville Dam second powerhouse (B2) intended to increase the guidance of juvenile salmonids into the juvenile bypass system (JBS) have resulted in high mortality and descaling rates of hatchery subyearling Chinook salmon during the 2008 juvenile salmonid passage season. To investigate the potential cause of the high mortality and descaling rates, an in situ water velocity measurement study was conducted using acoustic Doppler velocimeters (ADV) in the gatewell slot at Units 12A and 14A of B2. From the measurements collected the average approach velocity, sweep velocity, and the root mean square (RMS) value of the velocity fluctuations were calculated. The approach velocities measured across the face of the VBS varied but were mostly less than 0.3 m/s. The sweep velocities also showed large variances across the face of the VBS with most measurements being less than 1.5 m/s. This study revealed that the approach velocities exceeded criteria recommended by NOAA Fisheries and Washington State Department of Fish and Wildlife intended to improve fish passage conditions.

Hughes, James S.; Deng, Zhiqun; Weiland, Mark A.; Martinez, Jayson J.; Yuan, Yong

2011-11-22T23:59:59.000Z

325

Former Worker Medical Screening Program Brochure | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Medical Screening Program Brochure Medical Screening Program Brochure Former Worker Medical Screening Program Brochure June 2012 The FWP brochure provides important information to inform former and current DOE Federal, contractor, and subcontractor employees about the benefits and services offered under the DOE Former Worker Medical Screening Program. Some of the topics described in the brochure include: a description of the program, how it is implemented, who is eligible to participate, what tests are offered, where exams are conducted, and what organizations provide the exams. Former Worker Medical Screening Program Brochure More Documents & Publications Former Worker Program Brochure Former Worker Program Summary of Services 2012 Former Worker Medical Screening Program Annual Report

326

Suppression of color screening at large N  

Science Journals Connector (OSTI)

In large-N QCD, deconfinement by color screening is suppressed. The adjoint string tension is twice the fundamental string tension. Consequences for models of confinement are discussed, and a simple model of a confining large-N master field is given.

J. Greensite and M. B. Halpern

1983-05-15T23:59:59.000Z

327

D & D screening risk evaluation guidance  

SciTech Connect (OSTI)

The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D&D) facilities. Although this method has been developed for D&D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D&D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis.

Robers, S.K.; Golden, K.M.; Wollert, D.A.

1995-09-01T23:59:59.000Z

328

Light-scattering properties of a woven shade-screen material used for  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Light-scattering properties of a woven shade-screen material used for Light-scattering properties of a woven shade-screen material used for daylighting and solar heat-gain control Title Light-scattering properties of a woven shade-screen material used for daylighting and solar heat-gain control Publication Type Conference Paper LBNL Report Number LBNL-828E Year of Publication 2008 Authors Jonsson, Jacob C., Eleanor S. Lee, and Michael D. Rubin Conference Name SPIE Optics+Photonics Date Published 08/2008 Conference Location San Diego, CA Call Number LBNL-828E Abstract Shade-screens are widely used in commercial buildings as a way to limit the amount of direct sunlight that can disturb people in the building. The shade screens also reduce the solar heat-gain through glazing the system. Modern energy and daylighting analysis software such as EnergyPlus and Radiance require complete scattering properties of the scattering materials in the system.

329

1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Global health response more accurate Global health response more accurate with automated influenza surveillance January 31, 2011 LANL to certify automated influenza surveillance A compact, self-contained, automated system for surveillance and screening of potential pandemic strains of influenza and other deadly infectious diseases is a step closer to reality, thanks to an agreement between Los Alamos National Laboratory, the University of California Los Angeles School of Public Health, and HighRes Biosolutions of Boston, Massachussets. Researchers from LANL and the UCLA School of Public Health will test and certify a critical component of the High-Throughput Laboratory Network (HTLN) to be built by HighRes Biosolutions. The company will design the automated high-throughput extraction and screening system for a prototype Global Bio Lab-a compact, modular

330

National Security Science and Technology Initiative: Air Cargo Screening  

SciTech Connect (OSTI)

The non-intrusive inspection (NII) of consolidated air cargo carried on commercial passenger aircraft continues to be a technically challenging, high-priority requirement of the Department of Homeland Security's Science and Technology Directorate (DHS S&T), the Transportation Security Agency and the Federal Aviation Administration. The goal of deploying a screening system that can reliably and cost-effectively detect explosive threats in consolidated cargo without adversely affecting the flow of commerce will require significant technical advances that will take years to develop. To address this critical National Security need, the Battelle Memorial Institute (Battelle), under a Cooperative Research and Development Agreement (CRADA) with four of its associated US Department of Energy (DOE) National Laboratories (Oak Ridge, Pacific Northwest, Idaho, and Brookhaven), conducted a research and development initiative focused on identifying, evaluating, and integrating technologies for screening consolidated air cargo for the presence of explosive threats. Battelle invested $8.5M of internal research and development funds during fiscal years 2007 through 2009. The primary results of this effort are described in this document and can be summarized as follows: (1) Completed a gap analysis that identified threat signatures and observables, candidate technologies for detection, their current state of development, and provided recommendations for improvements to meet air cargo screening requirements. (2) Defined a Commodity/Threat/Detection matrix that focuses modeling and experimental efforts, identifies technology gaps and game-changing opportunities, and provides a means of summarizing current and emerging capabilities. (3) Defined key properties (e.g., elemental composition, average density, effective atomic weight) for basic commodity and explosive benchmarks, developed virtual models of the physical distributions (pallets) of three commodity types and three explosive benchmarks combinations, and conducted modeling and simulation studies to begin populating the matrix of commodities, threats, and detection technologies. (4) Designed and fabricated basic (homogeneous) commodity test pallets and fabricated inert stimulants to support experiments and to validate modeling/simulation results. (5) Developed/expanded the team's capabilities to conduct full-scale imaging (neutron and x-ray) experiments of air cargo commodities and explosive benchmarks. (6) Conducted experiments to improve the collection of trace particles of explosives from a variety of surfaces representative of air cargo materials by means of mechanical (air/vibration/pressure), thermal, and electrostatic methods. Air cargo screening is a difficult challenge that will require significant investment in both research and development to find a suitable solution to ensure the safety of passengers without significantly hindering the flow of commodities. The initiative funded by Battelle has positioned this group to make major contributions in meeting the air cargo challenge by developing collaborations, developing laboratory test systems, improving knowledge of the challenges (both technical and business) for air cargo screening, and increasing the understanding of the capabilities for current inspection methods (x-ray radiography, x-ray backscatter, etc.) and potential future inspection methods (neutron radiography, fusion of detector modalities, advanced trace detection, etc.). Lastly, air cargo screening is still an issue that will benefit from collaboration between Department of Energy Laboratories and Battelle. On January 7, 2010, DHS Secretary Napolitano joined White House Press Secretary Robert Gibbs and Assistant to the President for Counterterrorism and Homeland Security John Brennan to announce several recommendations DHS has made to the President for improving the technology and procedures used to protect air travel from acts of terrorism. (This announcement followed the 25 Dec'09 Delta/Northwest Airlines Flight 253 terror attack.) Secretary Napolitano out

Bingham, Philip R [ORNL; White, Tim [Pacific Northwest National Laboratory (PNNL); Cespedes, Ernesto [Idaho National Laboratory (INL); Bowerman, Biays [Brookhaven National Laboratory (BNL); Bush, John [Battelle

2010-11-01T23:59:59.000Z

331

'ELECTRIC FISH SCREEN By F. O. McMILLAN  

E-Print Network [OSTI]

'ELECTRIC FISH SCREEN .:f- By F. O. McMILLAN Associate Professor of Electrical Engineering, Oregon ~ '~ ' Electric screen ,_, _ Acknowledgments , , , _ Problems investigated ~ ~ ~ _ Experimentaldata -------- _ Observations after electrical tests ~ ~ _ Influence of water .lsistivity on the paralysis-voltage gradient

332

Screened Hybrid and DFT + U Studies of the Structural, Electronic...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Screened Hybrid and DFT + U Studies of the Structural, Electronic, and Optical Properties of U3O8. Screened Hybrid and DFT + U Studies of the Structural, Electronic, and Optical...

333

Weakly screened thermonuclear reactions in astrophysical plasmas: Improving Salpeter's model  

E-Print Network [OSTI]

This paper presents a detailed study of the electron degeneracy and nonlinear screening effects which play a crucial role in the validity of Salpeter's weak-screening model. The limitations of that model are investigated and an improved one is proposed which can take into account nonlinear screening effects. Its application to the solar pp reaction derives an accurate screening enhancement factor and provides a very reliable estimation of the associated neutrino flux uncertanties.

Theodore E. Liolios

2003-06-23T23:59:59.000Z

334

The Usage of Screen-Level Parameters and Microwave Brightness Temperature for Soil Moisture Analysis  

Science Journals Connector (OSTI)

This study focuses on testing two different soil moisture analysis systems based on screen-level parameters (2-m temperature T2m, 2-m relative humidity RH2m) and 1.4-GHz passive microwave brightness temperatures TB. First, a simplified extended ...

G. Seuffert; H. Wilker; P. Viterbo; M. Drusch; J-F. Mahfouf

2004-06-01T23:59:59.000Z

335

Screening of Receptor Antagonists Using Agonist-Activated Patch Clamp Detection in  

E-Print Network [OSTI]

Screening of Receptor Antagonists Using Agonist-Activated Patch Clamp Detection in Chemical 96 Go¨teborg, Sweden We present a capillary electrophoresis-patch clamp detection system optimized-spectrum glutamate receptor antagonist, were separated and detected by kainate-activated patch- clamped interneurons

Zare, Richard N.

336

A Screening Technique for Joint Chance-Constrained Programming for Air-Quality Management  

Science Journals Connector (OSTI)

This technical note presents a screening technique for using chance-constrained programming to achieve overall system (i.e., joint) reliability when there is statistical dependence between constraints representing an ambient air-quality requirement at ... Keywords: air quality control, environment, joint chance constraint, programming

Hyunhee An; J. Wayland Eheart

2007-07-01T23:59:59.000Z

337

Cobalt Precursors for High-Throughput Discovery of Base Metal Asymmetric Alkene Hydrogenation Catalysts  

Science Journals Connector (OSTI)

...earth-abundant elements such as iron and cobalt are attractive because...precursor, Co(acac) 3 (acac, acetylacetonate). A selection of commercially available...12515512 22 B. Plietker, Ed., Iron Catalysis in Organic Chemistry...

Max R. Friedfeld; Michael Shevlin; Jordan M. Hoyt; Shane W. Krska; Matthew T. Tudge; Paul J. Chirik

2013-11-29T23:59:59.000Z

338

PVD synthesis and high-throughput property characterization of Ni?Fe?Cr alloy libraries  

SciTech Connect (OSTI)

Three methods of alloy library synthesis, thick-layer deposition followed by interdiffusion, composition-spread codeposition and electron-beam melting of thick deposited layers, have been applied to Ni-Fe-Cr ternary and Ni-Cr binary alloys. Structural XRD mapping and mechanical characterization by means of nanoindentation have been used to characterize the properties of the libraries. The library synthesis methods are compared from the point of view of the structural and mechanical information they can provide.

Rar, A.; Frafjord, J.J.; Fowlkes, Jason D.; Specht, E.D.; Rack, P.D.; Santella, M.L.; Bei, H.; George, E.P.; Pharr, G.M. (Tennessee-K); (Tennessee-K); (ORNL)

2010-11-10T23:59:59.000Z

339

High-throughput film-densitometry: An efficient approach to generate large data sets  

SciTech Connect (OSTI)

A film-handling machine (robot) has been built which can, in conjunction with a commercially available film densitometer, exchange and digitize over 300 electron micrographs per day. Implementation of robotic film handling effectively eliminates the delay and tedium associated with digitizing images when data are initially recorded on photographic film. The modulation transfer function (MTF) of the commercially available densitometer is significantly worse than that of a high-end, scientific microdensitometer. Nevertheless, its signal-to-noise ratio (S/N) is quite excellent, allowing substantial restoration of the output to ''near-to-perfect'' performance. Due to the large area of the standard electron microscope film that can be digitized by the commercial densitometer (up to 10,000 x 13,680 pixels with an appropriately coded holder), automated film digitization offers a fast and inexpensive alternative to high-end CCD cameras as a means of acquiring large amounts of image data in electron microscopy.

Typke, Dieter; Nordmeyer, Robert A.; Jones, Arthur; Lee, Juyoung; Avila-Sakar, Agustin; Downing, Kenneth H.; Glaeser, Robert M.

2004-07-14T23:59:59.000Z

340

Technology assessment and feasibility study of high-throughput single cell force spectroscopy  

E-Print Network [OSTI]

In the last decade, the field of single cell mechanics has emerged with the development of high resolution experimental and computational methods, providing significant amount of information about individual cells instead ...

Cheng, He, M. Eng. Massachusetts Institute of Technology

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

High-Throughput 3D Homology Detection via NMR Resonance Assignment  

E-Print Network [OSTI]

-ray crystallography or Nuclear Magnetic Resonance (NMR), is very costly and time-consuming. Consequently protein and c is the maximum edge weight in an integer- weighted bipartite graph. Our experiments on real experimental data. Abbreviations used: NMR, nuclear magnetic resonance; RDC, residual dipolar coupling; 3D

Langmead, Christopher James

342

High-Throughput 3D Structural Homology Detection via NMR Resonance Christopher James Langmead  

E-Print Network [OSTI]

's structure experimentally, via X-ray crystallography or Nuclear Magnetic Resonance (NMR), is very costly bipartite graph. Our experiments on real NMR data from 3 different proteins against a database of 4-646-3173. Fax: 603-646-1672. Email: brd@cs.dartmouth.edu Abbreviations used: NMR, nuclear magnetic resonance

Richardson, David

343

High-throughput synthesis and characterization of vanadium mixed metal oxide pigments using synchroton radiation.  

E-Print Network [OSTI]

??UNA range of inorganic vanadium mixed metal oxides, with potential applications as inorganic pigments, have been synthesised and characterised in terms of their crystal structure, (more)

Russu, Sergio

2008-01-01T23:59:59.000Z

344

SUPPLEMENTAL INFORMATION Treatability of Complex Effluents in High-Throughput and Bench Scale Microbial  

E-Print Network [OSTI]

. The efficiency was calculated using only recovered hydrogen and combined hydrogen and methane, using the heat of combustion to calculate the energy contained in the gas. Figure S13. Open circuit gas production and COD

345

High throughput parallel backside contacting and periodic texturing for high-efficiency solar cells  

SciTech Connect (OSTI)

Disclosed are configurations of long-range ordered features of solar cell materials, and methods for forming same. Some features include electrical access openings through a backing layer to a photovoltaic material in the solar cell. Some features include textured features disposed adjacent a surface of a solar cell material. Typically the long-range ordered features are formed by ablating the solar cell material with a laser interference pattern from at least two laser beams.

Daniel, Claus; Blue, Craig A.; Ott, Ronald D.

2014-08-19T23:59:59.000Z

346

Analysis of High-Throughput Sequencing and Annotation Strategies for Phage Genomes  

E-Print Network [OSTI]

Background: Bacterial viruses (phages) play a critical role in shaping microbial populations as they influence both host mortality and horizontal gene transfer. As such, they have a significant impact on local and global ...

Chisholm, Sallie (Penny)

347

Potential of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials (presentation)  

Broader source: Energy.gov [DOE]

Presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

348

High-Throughput Methods To Assess Lipophilic and Hydrophilic Antioxidant Capacity of Food Extracts in Vitro  

Science Journals Connector (OSTI)

Assays comprising three probes for different mechanisms of antioxidant activity in food products have been modified to allow better comparison of the contributions of the different mechanisms to antioxidant capacity (AOC). ... The mixture was incubated at 50 C for 15 min, and the absorbance was measured at 760 nm (UV?vis spectrophotometer Lambda 12, Perkin-Elmer AG). ...

D. Jimenez-Alvarez; F. Giuffrida; F. Vanrobaeys; P. A. Golay; C. Cotting; A. Lardeau; Brendan J. Keely

2008-04-24T23:59:59.000Z

349

High-Throughput Program for the Discovery of NOx Reduction Catalysts...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

2004deerblint.pdf More Documents & Publications WA02042GENERALMOTORSPOWERTRAINDIVWaiverofDomestic.pdf Heavy-Duty NOx Emissions Control: Reformer-Assisted vs....

350

E-Print Network 3.0 - automated high throughput Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Engineering, Cornell University Collection: Chemistry ; Engineering 35 THE RABIT: A RAPID AUTOMATED BIODOSIMETRY TOOL FOR RADIOLOGICAL TRIAGE Summary: goals, and describe...

351

Bayesian Model Selection for High-dimensional High-throughput Data  

E-Print Network [OSTI]

(d + 2i) [ ??C?11? n? ]k ??C?11 ? ? 1 2 (2pin?) d 2 exp [ ? ??C?11? 2n? ] , (2.16) which leads to a Bayes? factor for testing hypothesis in equation (2.12) versus (2.13) that can be expressed as 15 BFM(2|1) = ??k k?1? i=0 (d... (d + 2i) [ ??C?11? n? ]k ??C?11 ? ? 1 2 (2pin?) d 2 exp [ ? ??C?11? 2n? ] , (2.16) which leads to a Bayes? factor for testing hypothesis in equation (2.12) versus (2.13) that can be expressed as 15 BFM(2|1) = ??k k?1? i=0 (d...

Joshi, Adarsh

2012-07-16T23:59:59.000Z

352

High-Throughput Methodology for Discovery of Metal-Organic Frameworks with a High  

E-Print Network [OSTI]

of California, Berkeley Lily Ackerman and Thomas R. Boussie Symyx Technologies, Inc. #12;A Tetrazolate

353

High-Throughput In Situ Parametric Studies of Cytochrome P450 Catalysis  

E-Print Network [OSTI]

of data quality in pharmaceutical industry, J Chromatogr Agenerally useful to pharmaceutical industries to facilitateimportance to the pharmaceutical industry in the metabolic

Traylor, Matthew John

2010-01-01T23:59:59.000Z

354

Antibody-functionalized nanoporous surfaces enable high throughput specific cell capture  

E-Print Network [OSTI]

Adhesion-based cell capture on surfaces in microfluidic devices forms the basis of numerous biomedical diagnostics and in vitro assays. Solid surface microfluidic platforms have been widely explored for biomedical diagnostics ...

Mittal, Sukant

2012-01-01T23:59:59.000Z

355

Low-damage high-throughput grazing-angle sputter deposition on graphene  

SciTech Connect (OSTI)

Despite the prevalence of sputter deposition in the microelectronics industry, it has seen very limited applications for graphene electronics. In this letter, we report systematic investigation of the sputtering induced damages in graphene and identify the energetic sputtering gas neutrals as the primary cause of graphene disorder. We further demonstrate a grazing-incidence sputtering configuration that strongly suppresses fast neutral bombardment and retains graphene structure integrity, creating considerably lower damage than electron-beam evaporation. Such sputtering technique yields fully covered, smooth thin dielectric films, highlighting its potential for contact metals, gate oxides, and tunnel barriers fabrication in graphene device applications.

Chen, C.-T.; Gajek, M.; Raoux, S. [IBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598 (United States); Casu, E. A. [IBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598 (United States); Politecnico di Torino, Turin 10129 (Italy)

2013-07-15T23:59:59.000Z

356

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage.  

E-Print Network [OSTI]

??Efficient hydrogen storage is required for fuel cell vehicles to be competitive with those driven by internal combustion engines. Current methods of storage such as (more)

Barcelo, Steven James

2009-01-01T23:59:59.000Z

357

High-throughput microfluidic single-cell RT-qPCR  

Science Journals Connector (OSTI)

...1, 2). Planar silicon molds were defined by photolithography, using photomasks designed with CAD software (AutoCAD, Autodesk Inc.) and printed on transparency films at a resolution of 20,000 dots per inch (CAD/Art services). The "control...

Adam K. White; Michael VanInsberghe; Oleh I. Petriv; Mani Hamidi; Darek Sikorski; Marco A. Marra; James Piret; Samuel Aparicio; Carl L. Hansen

2011-01-01T23:59:59.000Z

358

Dynamic analysis of MAPK signaling using a high-throughput microfluidic single-cell imaging platform  

Science Journals Connector (OSTI)

...steps are used to realize monolithic multilayer devices. Photolithography masks were designed by using AutoCAD software (Autodesk) and used to generate high-resolution (20,000 dpi) transparency masks (CAD/Art Services). Molds were fabricated...

R. J. Taylor; D. Falconnet; A. Niemist; S. A. Ramsey; S. Prinz; I. Shmulevich; T. Galitski; C. L. Hansen

2009-01-01T23:59:59.000Z

359

High-Throughput, High-Precision Hot Testing Tool for High-Brightness...  

Broader source: Energy.gov (indexed) [DOE]

Light-Emitting Diode Testing More Documents & Publications 2014 Solid-State Lighting Project Portfolio A Practical Primer to LED Technology LED Color Characteristics...

360

E-Print Network 3.0 - antileishmanial high-throughput drug Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

antileishmanial and antitrypanosomal Source: Redi, Peter - Institute of Organic Chemistry, Universitt Zrich Collection: Chemistry 14 FUTURE PROSPECTS FOR CHAGAS' DISEASE...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Attendees list from the U.S. Department of Energy's High Throughput...  

Broader source: Energy.gov (indexed) [DOE]

Larry Blair DOE Tom Boussie Symyx Technologies Bob Bowman JPL Larry Cook NIST Alan Cooper Air Products Kristin Deason Sentech Pete DeSanto Air Products R. Greg Downing NIST Mike...

362

Nanomolar-scale high-throughput chemistry for the synthesis of complex molecules  

Science Journals Connector (OSTI)

...Kuvelkar R. Hodgson R. Hyde L. A. Cox K. Favreau L. Parker E. M. Greenlee W. J. , Discovery of an orally available, brain penetrant BACE1 inhibitor that affords robust CNS A{beta} reduction . ACS Med. Chem. Lett. 3 , 897 902 ( 2012...

Alexander Buitrago Santanilla; Erik L. Regalado; Tony Pereira; Michael Shevlin; Kevin Bateman; Louis-Charles Campeau; Jonathan Schneeweis; Simon Berritt; Zhi-Cai Shi; Philippe Nantermet; Yong Liu; Roy Helmy; Christopher J. Welch; Petr Vachal; Ian W. Davies; Tim Cernak; Spencer D. Dreher

363

Evaluation of a New Remote Handling Design for High Throughput Annular Centrifugal Contactors  

SciTech Connect (OSTI)

Advanced designs of nuclear fuel recycling plants are expected to include more ambitious goals for aqueous based separations including; higher separations efficiency, high-level waste minimization, and a greater focus on continuous processes to minimize cost and footprint. Therefore, Annular Centrifugal Contactors (ACCs) are destined to play a more important role for such future processing schemes. Previous efforts defined and characterized the performance of commercial 5 cm and 12.5 cm single-stage ACCs in a cold environment. The next logical step, the design and evaluation of remote capable pilot scale ACCs in a hot or radioactive environment was reported earlier. This report includes the development of remote designs for ACCs that can process the large throughput rates needed in future nuclear fuel recycling plants. Novel designs were developed for the remote interconnection of contactor units, clean-in-place and drain connections, and a new solids removal collection chamber. A three stage, 12.5 cm diameter rotor module has been constructed and evaluated for operational function and remote handling in highly radioactive environments. This design is scalable to commercial CINC ACC models from V-05 to V-20 with total throughput rates ranging from 20 to 650 liters per minute. The V-05R three stage prototype was manufactured by the commercial vendor for ACCs in the U.S., CINC mfg. It employs three standard V-05 clean-in-place (CIP) units modified for remote service and replacement via new methods of connection for solution inlets, outlets, drain and CIP. Hydraulic testing and functional checks were successfully conducted and then the prototype was evaluated for remote handling and maintenance suitability. Removal and replacement of the center position V-05R ACC unit in the three stage prototype was demonstrated using an overhead rail mounted PaR manipulator. This evaluation confirmed the efficacy of this innovative design for interconnecting and cleaning individual stages while retaining the benefits of commercially reliable ACC equipment for remote applications in the nuclear industry. Minor modifications and suggestions for improved manual remote servicing by the remote handling specialists were provided but successful removal and replacement was demonstrated in the first prototype.

David H. Meikrantz; Troy G. Garn; Jack D. Law; Lawrence L. Macaluso

2009-09-01T23:59:59.000Z

364

High Throughput Identification, Purification and Structural Characterization of Water Soluble Protein Complexes in Desulfovibrio vulgaris  

SciTech Connect (OSTI)

Our scheme for the tagless purification of water soluble complexes. 10 g of protein from a crude bacterial extract is first fractionated by ammonium sulfate precipitation and then by a series of chromatographic steps: anion exchange (IEX), hydrophobic interaction (HIC), and finally size exclusion (Gel Filtration). Fractions from the last chromatography step are trypsin digested and peptides labeled with iTRAQ reagents to allow multiplexing and quantitation during mass spectrometric analysis. Elution profiles of identified proteins are then subjected to clustering analysis.

Dong,, Ming; Han, Bong-Gyoon; Liu, Hui-Hai; Malik, J.; Geller, Jil; Yang, Li; Choi, M.; Chandonia, John-Marc; Arbelaez, Pablo; Sterling, H. J.; Typke, Dieter; Shatsky, Max; Brenner, Steve; Fisher, Susan; Williams, Evan; Szakal, Evelin; Allen, S.; Hall, S. C.; Hazen, Terry; Witkowska, H. E.; Jin, Jiming; Glaeser, Robert; Biggin, Mark

2010-05-17T23:59:59.000Z

365

Development of a high throughput 3D perfused liver tissue bioreactor  

E-Print Network [OSTI]

This thesis describes the development of a device designed for culturing liver tissue in a 3D perfused environment. Cells form tissue inside miniature channels of a scaffold, and the tissue is perfused with culture medium ...

Inman, Samuel Walker

2006-01-01T23:59:59.000Z

366

Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-Throughput Microarrays  

Science Journals Connector (OSTI)

...Microarrays 1 Norihiro Sato Noriyoshi Fukushima Anirban Maitra Hiroyuki Matsubayashi...5-CTCTGTTTAGCACTGATAATG-3 (forward) and 5-TTTATTAGACTTGAGCTGATTC-3...5-CGGGAGATCAAGCAGAATG-3 (forward) and 5-AACGGCCTCGTTGTACTTG-3...61: 8540-8546, 2001. 5 Fukushima N., Sato N., Ueki T...

Norihiro Sato; Noriyoshi Fukushima; Anirban Maitra; Hiroyuki Matsubayashi; Charles J. Yeo; John L. Cameron; Ralph H. Hruban; and Michael Goggins

2003-07-01T23:59:59.000Z

367

Interfacing Capillary Electrophoresis and 2D-Infrared Spectroscopy for High Throughput Proteomics  

E-Print Network [OSTI]

and parameters defining the wettability of the substrate plate such as buffer conductivity, applied electric efficiency, the sample therefore needs to be concentrated onto an area while a linear motor stage is translating the substrate plate beneath. A high analyte area Optical

Rosso, Lula

368

E-Print Network 3.0 - aureus strains high-throughput Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

has been... . Staphylococcus aureus is a major human pathogen, and with ... Source: Buckling, Angus - Department of Zoology, University of Oxford Collection: Biology and Medicine...

369

Predicting gene function through systematic analysis and quality assessment of high-throughput data  

Science Journals Connector (OSTI)

......Fraser, A.G., Dong, Y., Poulin, G., Durbin, R., Gotta...concentration was then adjus-ted to approximately 1 106cells...locations had been permit-ted, the IC of the localization...Fraser,A.G., Dong,Y., Poulin,G., Durbin,R., Gotta......

Patrick Kemmeren; Thessa T. J. P. Kockelkorn; Theo Bijma; Rogier Donders; Frank C. P. Holstege

2005-04-01T23:59:59.000Z

370

WHAM: A High-throughput Sequence Alignment Method Yinan Li Allison Terrell Jignesh M. Patel  

E-Print Network [OSTI]

-1-4503-0661-4/11/06 ...$10.00. only a small portion (called a "read") of the genome. The human genome project delivered its anniversary of the sequencing of the first human genome [1, 21]. This key scientific discovery has been to drug discovery and drug design for personal- ized medicine. A crucial part of this first human genome

Patel, Jignesh

371

MCAM: Multiple Clustering Analysis Methodology for Deriving Hypotheses and Insights from High-Throughput Proteomic Datasets  

E-Print Network [OSTI]

Advances in proteomic technologies continue to substantially accelerate capability for generating experimental data on protein levels, states, and activities in biological samples. For example, studies on receptor tyrosine ...

Naegle, Kristen Marie

372

Air-stable ink for scalable, high-throughput layer deposition  

DOE Patents [OSTI]

A method for producing and depositing air-stable, easily decomposable, vulcanized ink on any of a wide range of substrates is disclosed. The ink enables high-volume production of optoelectronic and/or electronic devices using scalable production methods, such as roll-to-roll transfer, fast rolling processes, and the like.

Weil, Benjamin D; Connor, Stephen T; Cui, Yi

2014-02-11T23:59:59.000Z

373

High-throughput microfluidic single-cell RT-qPCR  

Science Journals Connector (OSTI)

...showed that on-chip analysis provides improved sensitivity...evaluated the efficiency and reliability of on-chip cell processing...followed by washing and analysis using a chemical lysis...creating isolated reactors combining the cell-capture...For mRNA digital PCR analysis cells were washed...

Adam K. White; Michael VanInsberghe; Oleh I. Petriv; Mani Hamidi; Darek Sikorski; Marco A. Marra; James Piret; Samuel Aparicio; Carl L. Hansen

2011-01-01T23:59:59.000Z

374

Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide  

E-Print Network [OSTI]

Strength of Monolayer Graphene Science 2008 321, 385-388. 5.Novoselov, K. S. The rise of graphene Nature 2007 6 183-191.A. Thermal properties of graphene and nanostructured carbon

Pleskot, Dennis

2013-01-01T23:59:59.000Z

375

Ultra-high-aspect-ratio nanofluidic channels for high-throughput biological applications  

E-Print Network [OSTI]

The development of micro/nanofluidics is expected to be the enabling technology for sample preparation of proteomic biosamples, which has been the bottleneck in proteomics. Most microfabricated nanofluidic channels, such ...

Mao, Pan

2009-01-01T23:59:59.000Z

376

Polymer microfluidic device for high-throughput single-cell encapsulation, lysis, and biological assay  

E-Print Network [OSTI]

rheology through microfluidics, Advanced Materials, vol.Berthier and P. Silberzan, Microfluidics for Biotechnology.A. P. Lee, Droplet microfluidics, Lab on a Chip, vol. 8,

Brackbill, Timothy Peter

2012-01-01T23:59:59.000Z

377

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage  

E-Print Network [OSTI]

Metal Hydrides for Hydrogen Storage by Steven James BarceloMetal Hydrides for Hydrogen Storage by Steven James BarceloCo-chair Efficient hydrogen storage is required for fuel

Barcelo, Steven James

2009-01-01T23:59:59.000Z

378

High-Throughput/Combinatorial Techniques in Hydrogen Storage Materials R&D (presentation)  

Broader source: Energy.gov [DOE]

Meeting Background, Purpose and Agenda presented at the U.S. Department of Energy's Hydrogen Storage Meeting held June 26, 2007 in Bethesda, Maryland.

379

High-throughput experimental and computational tools for exploring immunity and the microbiome  

E-Print Network [OSTI]

Humans live in association with trillions of microbes and yet we know remarkably little about their symbiotic relationship. The role these microorganisms have in humans has been characterized only in the case of few bacteria ...

Papa, Eliseo

2012-01-01T23:59:59.000Z

380

Weighted poolingpractical and cost-effective techniques for pooled high-throughput sequencing  

Science Journals Connector (OSTI)

......Sophisticated pooling designs require belief-propagation...compressed sensing design remains an open one...strategies is based on crossing information between...problem along the pipeline does not influence...a first step in a road that may eventually utilize more complex designs to a greater benefit......

David Golan; Yaniv Erlich; Saharon Rosset

2012-06-15T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

ADAPTIVE MATRIX METRICS FOR ATTRIBUTE DEPENDENCE ANALYSIS IN DIFFERENTIAL HIGH-THROUGHPUT DATA  

E-Print Network [OSTI]

. Corresponding author email: stricker@ipk-gatersleben.de ABSTRACT Data-driven metric adaptation is proposed descent method [7]. 2. METHOD ­ MATRIX LEARNING As input q-dimensional row vectors x R1?q are as- sumed

Biehl, Michael

382

Investigation of Extra-Large Pore Zeolite Synthesis by a High-Throughput Approach  

Science Journals Connector (OSTI)

A.C. thanks the project consolider Ingenio MULTICAT for financial support. ... Klein, J.; Lehmann, C. W.; Schmidt, H. W.; Maier, W. F. Angew. ...

Jiuxing Jiang; Yan Xu; Peng Cheng; Qiming Sun; Jihong Yu; Avelino Corma; Ruren Xu

2011-10-12T23:59:59.000Z

383

The Development of a High-throughput Microdroplet Bioreactor Device for Microbial Studies  

E-Print Network [OSTI]

Current PCR Polymerase Chain Reaction MOS-FET Metal-Oxide-Semiconductor Field-Effect Transistor BSA Bovine Serum Albumin GFP Green Fluorescent Protein RFP Red Fluorescent Protein LED Light Emitting Diode PMT Photomultiplier Tubes...

Guzman, Adrian

2012-10-19T23:59:59.000Z

384

Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray  

E-Print Network [OSTI]

Atomic force microscopy has been applied to an acrylate polymer microarray to achieve a full topographic characterisation. This process discovered a small number of hydro-responsive materials created from monomers with ...

Hook, Andrew L.

385

Development of a high-throughput fermentation assay using colorimetric measurement of gas production.  

E-Print Network [OSTI]

??Typical methods for determining ethanol production from biomass feedstocks involve the use of High Performance Liquid Chromatography (HPLC) or Gas Chromatography (GC). Such methods require (more)

Bly, Steven

2008-01-01T23:59:59.000Z

386

Applications of high throughput (combinatorial) methodologies to electronic, magnetic, optical, and energy-related materials  

E-Print Network [OSTI]

materials science for electronic, magnetic, optical, and energy-related materials. It is expected that high, and energy-related materials Martin L. Green, Ichiro Takeuchi, and Jason R. Hattrick-Simpers Citation: J) methodologies to electronic, magnetic, optical, and energy-related materials Martin L. Green,1 Ichiro Takeuchi,2

Rubloff, Gary W.

387

VLPW: The Very Long Packet Window Architecture for High Throughput Network-On-Chip Router Designs  

E-Print Network [OSTI]

throughput. With the VLPW architecture, we propose two scheduling schemes: Global Fairness and Global Diversity. Our simulation results show that the VLPW router achieves more than 20% throughput improvement without negative effects on zero-load latency....

Gu, Haiyin

2012-10-19T23:59:59.000Z

388

A Warm Near-Infrared High-Resolution Spectrograph with Very High Throughput (WINERED)  

E-Print Network [OSTI]

WINERED is a newly built high-efficiency (throughput$ > 25-30\\%$) and high-resolution spectrograph customized for short NIR bands at 0.9-1.35 ${\\rm \\mu}$m. WINERED is equipped with ambient temperature optics and a cryogenic camera using a 1.7 ${\\rm \\mu}$m cut-off HgCdTe HAWAII-2RG array detector. WINERED has two grating modes: one with a conventional reflective echelle grating (R$\\sim$28,300), which covers 0.9-1.35 $\\mu$m simultaneously, the other with ZnSe or ZnS immersion grating (R$\\sim$100,000). We have completed the development of WINERED except for the immersion grating, and started engineering and science observations at the Nasmyth platform of the 1.3 m Araki Telescope at Koyama Astronomical Observatory of Kyoto-Sangyo University in Japan. We confirmed that the spectral resolution ($R\\sim$ 28,300) and the throughput ($>$ 40\\% w/o telescope/atmosphere/array QE) meet our specifications. We measured ambient thermal backgrounds (e.g., 0.06 ${\\rm [e^{-}/sec/pixel]}$ at 287 K), which are roughly consistent ...

Kondo, Sohei; Kobayashi, Naoto; Yasui, Chikako; Mito, Hiroyuki; Fukue, Kei; Nakanishi, Kenshi; Kawanishi, Takafumi; Nakaoka, Tetsuya; Otsubo, Shogo; Kinoshita, Masaomi; Kitano, Ayaka; Hamano, Satoshi; Mizumoto, Misaki; Yamamoto, Ryo; Izumi, Natsuko; Matsunaga, Noriyuki; Kawakita, Hideyo

2015-01-01T23:59:59.000Z

389

Generation of expression vectors for high-throughput functional analysis of target genes in Schizosaccharomyces pombe  

Science Journals Connector (OSTI)

An immediate challenge in the post-genomic era is to assign a biological functions to proteins unraveled by genome analysis. This report is based on studies conducted using Schizosaccharomyces pombe, a simple mod...

Jiwon Ahn; Chung-Hae Choi; Chang-Mo Kang; Chun-Ho Kim

2009-12-01T23:59:59.000Z

390

High-throughput Characterization of Porous Materials Using Graphics Processing Units  

E-Print Network [OSTI]

framework atoms. Using a parallel flood fill CPU algorithm,segmentation using a parallel flood fill (also known as seeddescribed in Ref. 39 Flood fill is a recursive algorithm to

Kim, Jihan

2013-01-01T23:59:59.000Z

391

Outbreak Investigation Using High-Throughput Genome Sequencing within a Diagnostic Microbiology Laboratory  

Science Journals Connector (OSTI)

...positive culture to the completion of sequencing (prior...bioMerieux). Aside from the index case, three out of...BPH0532, BPH0657 [index case], and BPH0658...culture to sequence completion (prior to data analysis...positive culture to completion of sequencing (prior...

Norelle L. Sherry; Jessica L. Porter; Torsten Seemann; Andrew Watkins; Timothy P. Stinear; Benjamin P. Howden

2013-02-13T23:59:59.000Z

392

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage  

E-Print Network [OSTI]

affect the fundamental changes to electronic structure thatunderstood. A fundamental study of the electronic structure

Barcelo, Steven James

2009-01-01T23:59:59.000Z

393

Guidance for Developing Ecological Soil Screening Levels  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Developing Developing Ecological Soil Screening Levels OSWER Directive 9285.7-55 U.S. Environmental Protection Agency Office of Solid Waste and Emergency Response 1200 Pennsylvania Avenue, N.W. Washington, DC 20460 November 2003 This Page Intentionally Left Blank EXECUTIVE SUMMARY This document describes the process used to derive a set of risk-based ecological soil screening levels (Eco-SSLs) for many of the soil contaminants that are frequently of ecological concern for plants and animals at hazardous waste sites and provides guidance for their use. The Eco-SSL derivation process represents the group effort of a multi-stakeholder workgroup consisting of federal, state, consulting, industry, and academic participants led by the U.S. Environmental Protection Agency Office of Superfund Remediation and Technology Innovation (OSRTI). The

394

Color screening in cold quark matter  

E-Print Network [OSTI]

We compute color screening at finite quark chemical potentials cold quark matter at the one-loop level, comparing the normal, BCS paired U(1)_em, or Higgs, and a singlet phase with color-singlet condensate near the Fermi surface. The latter phase is computed in the example of two-color QCD with a color singlet diquark condensate. In contrast to the normal and Higgs phases, neither electric nor magnetic screening masses appear in the singlet phase. The absence of a magnetic mass, within a perturbative framework, is a consequence of proper treatment of gauge invariance. While at large momenta the gluon self-energies approach those in the normal phase, the medium contributions to the infrared region below a scale of the mass gap are substantially suppressed. Infrared gluons at low quark density in the singlet phase appear protected from medium effects, unless the quark-gluon vertices are significantly enhanced in the infrared.

Kojo, Toru

2014-01-01T23:59:59.000Z

395

Surfactant screening of diesel-contaminated soil  

SciTech Connect (OSTI)

At one installation, approximately 60,000 gal of No. 2 diesel fuel leaked into the subsurface environment, with contamination at depths of 6 to 34 m below the surface. Argonne National Laboratory was contracted to perform treatability studies for site remediation. The treatability studies focused on four separate phases: (1) leachability studies on the various contaminated soil borings, (2) air stripping studies, (3) bioremediation studies, and (4) surfactant screening/surfactant flooding studies. This paper summarizes the fourth phase of the research program in which twenty-one surfactants were screened for possible use to mobilize the organics from the contaminated soil prior to bioremediation. Anionic surfactants resulted in the greatest degree of diesel mobilization. The most promising surfactants will be employed on actual contaminated soil samples obtained from the site. 18 refs., 16 figs., 1 tab.

Peters, R.W.; Montemagno, C.D.; Shem, L. (Argonne National Lab., IL (USA)); Lewis, B.A. (Northwestern Univ., Evanston, IL (USA). Dept. of Civil Engineering)

1990-01-01T23:59:59.000Z

396

Screening current effects in Josephson junction arrays  

E-Print Network [OSTI]

The purpose of this work is to compare the dynamics of arrays of Josephson junctions in presence of magnetic field in two different frameworks: the so called XY frustrated model with no self inductance and an approach that takes into account the screening currents (considering self inductances only). We show that while for a range of parameters the simpler model is sufficiently accurate, in a region of the parameter space solutions arise that are not contained in the XY model equations.

A. Petraglia; G. Filatrella; G. Rotoli

1995-07-28T23:59:59.000Z

397

Screening technology reduces ash in spiral circuits  

SciTech Connect (OSTI)

In 2006, the James River Coal Co. selected the Stack Sizer to remove the minus 100 mesh high ash clay fraction from the clean coal spiral product circuits at the McCoy-Elkhorn Bevins Branch prep plant and at the Blue Diamond Leatherwood prep plant in Kentucky. The Stack Sizer is a multi-deck, high-frequency vibrating screen capable of separations as fine as 75 microns when fitted with Derrick Corp.'s patented high open area urethane screen panels. Full-scale lab tests and more than 10 months of continuous production have confirmed that the Stack Sizer fitted with Derrick 100 micron urethane screen panels consistently produces a clean coal fraction that ranges from 8 to 10% ash. Currently, each five-deck Stack Sizer operating at the Bevins Branch and Leatherwood prep plants is producing approximately 33 tons per hour of clean coal containing about 9% ash. This represents a clean coal yield of about 75% and an ash reduction of about 11% from the feed slurry. 3 figs. 2 tabs.

Brodzik, P. [Derrick Corp., Buffalo, NY (United States)

2007-05-15T23:59:59.000Z

398

Radiation Tolerant Programmable Power Supply for the LHC Beam Screen Heaters  

E-Print Network [OSTI]

For the next LHC run, it is required to install 200W of heating capacity per LHC beam screen heater to regenerate the beam screen by desorption of gas trapped on its walls. In the LHC, there are 272 beam screen heaters and the associated electronics limit presently the heating capacity to 25W. Those electronics are, for the most part, installed inside the LHC tunnel and exposed to its radiation environment. This paper describes the development of a new programmable power supply card that will be integrated into the existing LHC radiation tolerant electronic infrastructure used by the cryogenic system. Radiation tests were undertaken to qualify a power switch capable of coping with the 230Vrms grid voltage and an analog signal multiplexer; these components are required respectively for satisfying the higher power requirements and for reducing the overall cost by using a single analog to digital converter to sample all the signals.

Casas, J

2014-01-01T23:59:59.000Z

399

Savannah River Site, Former Production Workers Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Site, Former Production Workers Screening Projects Site, Former Production Workers Screening Projects Savannah River Site, Former Production Workers Screening Projects Project Name: National Supplemental Screening Program Covered DOE Site: SRS Worker Population Served: Production Workers Principal Investigator: Donna Cragle, PhD Toll-free Telephone: (866) 812-6703 Website: http://www.orau.org/nssp/ This project is conducted by the Oak Ridge Associated Universities (ORAU), as a component of its National Supplemental Screening Program. ORAU has teamed with its partners, Comprehensive Health Services, National Jewish Health, the University of Colorado Denver, and Axion Health, to run the program. Construction Worker Screening Projects Construction Worker Projects, Former Worker Medical Screening Program (FWP)

400

Electrical interactions in the cell: Asymmetric screening in a watery antiverse  

Science Journals Connector (OSTI)

The problem of electrostatics in biomolecular systems presents an excellent opportunity for cross-disciplinary science and a context in which fundamental physics is called for to answer complex questions. Due to the large density in biological cells of charged biomacromolecules such as protein factors and DNA it is challenging to understand quantitatively the electric forces in these systems. Two questions are especially puzzling. First how is it that such a dense system of charged molecules does not simply aggregate in random and non-functional ways? Second since some mechanism apparently prevents such aggregation how is it that binding of biomolecules still occurs so reliably? Recognizing the role of water as a universal solvent in living systems is key to understanding these questions. We present a simplified physical model in which water is regarded as a medium of high dielectric constant that nevertheless exhibits the key features essential for answering the two questions presented. The answer to the first question lies in the strong screening ability of water which reduces the energy scale of the electrostatic interactions. Furthermore our model reveals the existence of asymmetric screening a pronounced asymmetry between the screening for a system with like charges and that for a system with opposite charges and this provides an answer to the second question.

T. P. Doerr

2014-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Screened Coulomb interactions in metallic alloys. ??II.?Screening beyond the single-site and atomic-sphere approximations  

Science Journals Connector (OSTI)

A quantitative description of the configurational part of the total energy of metallic alloys with substantial atomic size difference cannot be achieved in the atomic-sphere approximation: It needs to be corrected at least for the multipole-moment interactions in the Madelung part of the one-electron potential and energy. In the case of a random alloy such interactions can be accounted for only by lifting the atomic-sphere and single-site approximations, in order to include the polarization due to local environment effects. Nevertheless, a simple parametrization of the screened Coulomb interactions for the ordinary single-site methods, including the generalized perturbation method, is still possible. We obtained such a parametrization for bulk and surface NiPt alloys, which allows one to obtain quantitatively accurate effective interactions in this system.

A. V. Ruban; S. I. Simak; P. A. Korzhavyi; H. L. Skriver

2002-06-26T23:59:59.000Z

402

Abstract B54: Latina farmworkers: Relationships between Pap screening behaviors, acculturation, and cultural cancer screening scales  

Science Journals Connector (OSTI)

...screening behavior and intent to undergo Pap tests among Mexican farmworker women in South...specified 1) Mexican immigrant, 2) no Pap test in over 2 years, 3) 20 women who lived...assessed using the Kruskal-Wallis rank test. When the test was statistically significant...

Lisa C. Watson; Yelena Tarasenko; Moya Alfonso; Claudia Reyes-Garcia; John S. Luque

2014-11-01T23:59:59.000Z

403

NEPA SCREENING FORM I Document Number: DOE/CX-00029 I-:::--=---:-------~----'-~---  

Broader source: Energy.gov (indexed) [DOE]

SCREENING FORM SCREENING FORM I Document Number: DOE/CX-00029 I-:::--=---:-------~----'-~--- I. Project Title: Project L-691, 200 West Area Sanitary Sewage Lagoon n. Project Description and Location (including time period over which proposed action will occur and project dimensions - e.g., acres displaced/disturbed, excavation length/depth, etc.): Project L-691 will construct a sanitary sewage lagoon system near the 200 West Area of the Hanford Site. This sanitary sewage lagoon system will include a septage dump station, a multi-cell sewage lagoon plant, a septage stabilization facility, and an intermittent filter system with an evaporative lagoon. Current plans are to locate the new facility directly north of the 200 West Area perimeter fence line; near

404

Non-equilibrium thermodynamics of gravitational screens  

E-Print Network [OSTI]

We study the Einstein gravity equations projected on a timelike surface, which represents the time evolution of what we call a gravitational screen. We show that such a screen possesses a surface tension and an internal energy, and that the Einstein equations reduce to the thermodynamic equations of a viscous bubble. We also provide a complete dictionary between gravitational and thermodynamical variables. In the non-viscous cases there are three thermodynamic equations which characterise a bubble dynamics: These are the first law, the Marangoni flow equation and the Young-Laplace equation. In all three equations the surface tension plays a central role: In the first law it appears as a work term per unit area, in the Marangoni flow its gradient drives a force, and in the Young-Laplace equation it contributes to a pressure proportional to the surface curvature. The gravity equations appear as a natural generalization of these bubble equations when the bubble itself is viscous and dynamical. In particular, it shows that the mechanism of entropy production for the viscous bubble is mapped onto the production of gravitational waves. We also review the relationship between surface tension and temperature, and discuss the usual black-hole thermodynamics from this point of view.

Laurent Freidel; Yuki Yokokura

2014-05-19T23:59:59.000Z

405

Color screening in cold quark matter  

E-Print Network [OSTI]

We compute---at finite quark chemical potentials---the color screening of cold quark matter at the one-loop level, comparing the normal, BCS-paired U(1)em (or Higgs) phase and a singlet phase with color-singlet condensate near the Fermi surface. The latter phase is computed using the example of two-color QCD with a color-singlet diquark condensate. In contrast to the normal and Higgs phases, neither electric nor magnetic screening masses appear in the singlet phase. The absence of a magnetic mass, within a perturbative framework, is a consequence of the proper treatment of gauge invariance. While at large momenta the gluon self-energies approach those in the normal phase, the medium contributions to the infrared region below a scale of the mass gap are substantially suppressed. Infrared gluons at low quark density in the singlet phase appear protected from medium effects, unless the quark-gluon vertices are significantly enhanced in the infrared.

Toru Kojo; Gordon Baym

2014-04-04T23:59:59.000Z

406

FIELD SCREENING FOR HALOGENATED VOLATILE ORGANIC COMPOUNDS  

SciTech Connect (OSTI)

Western Research Institute (WRI) initiated exploratory work towards the development of new field screening methodology and a test kit to measure halogenated volatile organic compounds (VOCs) in the field. Heated diode and corona discharge sensors are commonly used to detect leaks of refrigerants from air conditioners, freezers, and refrigerators. They are both selective to the presence of carbon-halogen bonds. Commercially available heated diode and corona discharge leak detectors were procured and evaluated for halogenated VOC response. The units were modified to provide a digital readout of signal related to VOC concentration. Sensor response was evaluated with carbon tetrachloride and tetrachloroethylene (perchloroethylene, PCE), which represent halogenated VOCs with and without double bonds. The response characteristics were determined for the VOCs directly in headspace in Tedlar bag containers. Quantitation limits in air were estimated. Potential interferences from volatile hydrocarbons, such as toluene and heptane, were evaluated. The effect of humidity was studied also. The performance of the new devices was evaluated in the laboratory by spiking soil samples and monitoring headspace for halogenated VOCs. A draft concept of the steps for a new analytical method was outlined. The results of the first year effort show that both devices show potential utility for future analytical method development work towards the goal of developing a portable test kit for screening halogenated VOCs in the field.

John F. Schabron; Joseph F. Rovani Jr.; Theresa M. Bomstad

2002-06-01T23:59:59.000Z

407

Infrared-Based Screening System Oak Ridge National Laboratory  

E-Print Network [OSTI]

) sensors or cameras, video images, and vehicle position sensors, and are generically known as infrared in enforcement was confirmed. Background -- Since 2007, ORNL has been involved in data collection efforts

408

Preliminary ecotoxicity assessment thresholds: Setting screening values for terrestrial systems  

SciTech Connect (OSTI)

How does one address the question of what level of environmental contamination causes adverse effects in plants and wildlife based solely on information from the ecotoxicology literature? One is confronted with a database derived from studies conducted in different laboratories, with different protocols, on different species that address different toxicity endpoints. Rarely will this information be directly applicable to the species of interest. How then are priorities set to sort the literature data in order of relevance to needs? Using decision analysis theory in an analytical hierarchy procedure the authors queried a panel of experts to define which components of a study make it more or less applicable to determining toxicity thresholds for organisms in their natural environment. A questionnaire guided them through a series of pairwise comparisons that enabled them to rank the importance of study duration, endpoint, and other reported variables. Each study from the literature can then be ranked according to the relative weights given to each of the categories and its usefulness determined for setting threshold values for a species of interest.

Fairbrother, A.; Kapustka, L.A.; Anderson, S.A. [Ecological Planning and Toxicology, Inc., Corvallis, OR (United States)

1994-12-31T23:59:59.000Z

409

Weldon Spring Plant, Former Construction Workers Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Workers Screening Projects Workers Screening Projects Weldon Spring Plant, Former Construction Workers Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Weldon Spring Plant Worker Population Served: Construction workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

410

Hanford Former Workers, Construction Worker Screening Projects | Department  

Broader source: Energy.gov (indexed) [DOE]

Hanford Former Workers, Construction Worker Screening Projects Hanford Former Workers, Construction Worker Screening Projects Hanford Former Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Hanford Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Local Outreach Office: Sherry Gosseen 3021 W. Clearwater Ave., Ste. 204 Kennewick, WA 99336 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

411

Weldon Spring Plant, Former Construction Worker Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Weldon Spring Plant, Former Construction Worker Screening Projects Weldon Spring Plant, Former Construction Worker Screening Projects Weldon Spring Plant, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Weldon Spring Plant Worker Population Served: Construction workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

412

Fuel Cell Technologies Office: HT Combinatorial Screening of Novel  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HT Combinatorial HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) to someone by E-mail Share Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Facebook Tweet about Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Twitter Bookmark Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Google Bookmark Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Delicious Rank Fuel Cell Technologies Office: HT Combinatorial Screening of

413

Savannah River Site, Former Construction Worker Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Savannah River Site, Former Construction Worker Screening Projects Savannah River Site, Former Construction Worker Screening Projects Savannah River Site, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: SRS Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Local Outreach Office: Charles Jernigan 1250 A Reynolds Street Augusta, GA 30901 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

414

Former Worker Medical Screening Program Implementation | Department of  

Broader source: Energy.gov (indexed) [DOE]

Former Former Worker Medical Screening Program Implementation Former Worker Medical Screening Program Implementation Program implementation focuses on four specific activities, which are: Outreach: Identify and notify eligible DOE workers about FWP medical screening services. Medical Screening: Provide medical screening exams that are designed to check for health conditions related to occupational exposures to former workers who choose to participate in the program, including a re-screen exam every three years. Communicating Results: Provide exam results to participants, as well as information regarding any conditions that may require follow-up medical care with their personal physicians or specialists, and provide information regarding possible compensation for work-related illnesses. Follow-up care

415

2012 Former Worker Medical Screening Program Annual Report | Department of  

Broader source: Energy.gov (indexed) [DOE]

Information Center » Worker » Former Worker Program » 2012 Information Center » Worker » Former Worker Program » 2012 Former Worker Medical Screening Program Annual Report 2012 Former Worker Medical Screening Program Annual Report February 2013 The 2012 Annual Report presents a detailed overview of the accomplishments, progress, and future endeavors of the U.S. Department of Energy Former Worker Medical Screening Program. The report describes how the program is implemented, what organizations are involved in the medical screening efforts, and what the medical findings have been to date. 2012 Former Worker Medical Screening Program Annual Report More Documents & Publications Former Worker Program Medical Protocol Former Worker Medical Screening Program Brochure Former Worker Program Brochure DOE Technical Standards Program

416

Bush Administration to Expand Beryllium Disease Screening Program |  

Broader source: Energy.gov (indexed) [DOE]

Bush Administration to Expand Beryllium Disease Screening Program Bush Administration to Expand Beryllium Disease Screening Program Bush Administration to Expand Beryllium Disease Screening Program February 23, 2005 - 10:27am Addthis Former employees of DOE vendors eligible for free screening WASHINGTON, DC - U.S. Secretary of Energy Samuel W. Bodman today announced the Department of Energy (DOE) will expand a beryllium screening program to include former employees of now-defunct DOE beryllium vendor companies across the country. Beryllium is a component used in nuclear weapons built by the Department of Energy. "Through no fault of their own, these Cold Warriors were left out in the cold when their former employers went out of business. By expanding this screening program, President Bush and the Department of Energy honor these

417

Paducah Gaseous Diffusion Plant, Construction Worker Screening Project |  

Broader source: Energy.gov (indexed) [DOE]

Paducah Gaseous Diffusion Plant, Construction Worker Screening Paducah Gaseous Diffusion Plant, Construction Worker Screening Project Paducah Gaseous Diffusion Plant, Construction Worker Screening Project Project Name: Building Trades National Medical Screening Program Covered DOE Site: Paducah Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (888) 464-0009 Local Outreach Office: Joe Hudson 1930 North 13th Street Paducah, KY 42001 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

418

Federal Renewable Energy Screening Assistant | Open Energy Information  

Open Energy Info (EERE)

Federal Renewable Energy Screening Assistant Federal Renewable Energy Screening Assistant Jump to: navigation, search Tool Summary Name: Federal Renewable Energy Screening Assistant (FRESA) Agency/Company /Organization: NREL Sector: Energy Focus Area: Biomass, Solar, Wind Topics: Implementation Resource Type: Software/modeling tools Website: analysis.nrel.gov/fresa/ OpenEI Keyword(s): EERE tool, FRESA, Federal Renewable Energy Screening Assistant References: FRESA homepage [1] Logo: Federal Renewable Energy Screening Assistant (FRESA) FRESA, is designed to help identify which renewable energy technologies are appropriate for implementation at both the facility and building scale. The Federal Renewable Energy Screening Assistant, or FRESA, is designed to help identify which renewable energy technologies are appropriate for

419

Oak Ridge Reservation Former Workers, Construction Worker Screening  

Broader source: Energy.gov (indexed) [DOE]

Oak Ridge Reservation Former Workers, Construction Worker Screening Oak Ridge Reservation Former Workers, Construction Worker Screening Projects Oak Ridge Reservation Former Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Oak Ridge K-25 Gaseous Diffusion Plant, Y-12, Oak Ridge National Laboratory (ORNL or X-10) Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPh, MHA, MPH Toll-free Telephone: (888) 464-0009 Local Outreach Office: Kim Cranford, RN 708 South Illinois Avenue, Suite E103 Oak Ridge, TN 37830 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos,

420

Fernald, Former Construction Worker Screening Projects | Department of  

Broader source: Energy.gov (indexed) [DOE]

Fernald, Former Construction Worker Screening Projects Fernald, Former Construction Worker Screening Projects Fernald, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Fernald Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: 1-888-464-0009 Local Outreach Office: Lou Doll 1550 Chase Avenue Cincinnati, OH 45223 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Waste Isolation Pilot Plant, Former Construction Worker Screening Projects  

Broader source: Energy.gov (indexed) [DOE]

Construction Worker Screening Construction Worker Screening Projects Waste Isolation Pilot Plant, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: WIPP Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPh, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

422

Brush Luckey Plant, Former Construction Worker Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Brush Luckey Plant, Former Construction Worker Screening Projects Brush Luckey Plant, Former Construction Worker Screening Projects Brush Luckey Plant, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Brush Luckey Plant Worker Population Served: Construction workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: 1-888-464-0009 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

423

Strong plasma screening in thermonuclear reactions: Electron drop model  

Science Journals Connector (OSTI)

We analyze enhancement of thermonuclear fusion reactions due to strong plasma screening in dense matter using a simple electron drop model. In the model we assume fusion in a potential that is screened by an effective electron cloud around colliding nuclei (extended Salpeter ion-sphere model). We calculate the mean-field screened Coulomb potentials for atomic nuclei with equal and nonequal charges, appropriate astrophysical S factors, and enhancement factors of reaction rates. As a byproduct, we study the analytic behavior of the screening potential at small separations between the reactants. In this model, astrophysical S factors depend not only on nuclear physics but on plasma screening as well. The enhancement factors are in good agreement with calculations by other methods. This allows us to formulate a combined, pure analytic model of strong plasma screening in thermonuclear reactions. The results can be useful for simulating nuclear burning in white dwarfs and neutron stars.

P. A. Kravchuk and D. G. Yakovlev

2014-01-09T23:59:59.000Z

424

Strong plasma screening in thermonuclear reactions: Electron drop model  

E-Print Network [OSTI]

We analyze enhancement of thermonuclear fusion reactions due to strong plasma screening in dense matter using a simple electron drop model. The model assumes fusion in a potential that is screened by an effective electron cloud around colliding nuclei (extended Salpeter ion-sphere model). We calculate the mean field screened Coulomb potentials for atomic nuclei with equal and nonequal charges, appropriate astrophysical S factors, and enhancement factors of reaction rates. As a byproduct, we study analytic behavior of the screening potential at small separations between the reactants. In this model, astrophysical S factors depend not only on nuclear physics but on plasma screening as well. The enhancement factors are in good agreement with calculations by other methods. This allows us to formulate the combined, pure analytic model of strong plasma screening in thermonuclear reactions. The results can be useful for simulating nuclear burning in white dwarfs and neutron stars.

Kravchuk, P A

2014-01-01T23:59:59.000Z

425

Strong plasma screening in thermonuclear reactions: Electron drop model  

E-Print Network [OSTI]

We analyze enhancement of thermonuclear fusion reactions due to strong plasma screening in dense matter using a simple electron drop model. The model assumes fusion in a potential that is screened by an effective electron cloud around colliding nuclei (extended Salpeter ion-sphere model). We calculate the mean field screened Coulomb potentials for atomic nuclei with equal and nonequal charges, appropriate astrophysical S factors, and enhancement factors of reaction rates. As a byproduct, we study analytic behavior of the screening potential at small separations between the reactants. In this model, astrophysical S factors depend not only on nuclear physics but on plasma screening as well. The enhancement factors are in good agreement with calculations by other methods. This allows us to formulate the combined, pure analytic model of strong plasma screening in thermonuclear reactions. The results can be useful for simulating nuclear burning in white dwarfs and neutron stars.

P. A. Kravchuk; D. G. Yakovlev

2014-01-11T23:59:59.000Z

426

Former Worker Program - Defunct Beryllium Vendor Screening Program  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Defunct Beryllium Vendor Screening Program Defunct Beryllium Vendor Screening Program Former Worker Medical Screening Program (FWP) In February 2005, DOE expanded the beryllium screening program to include former employees of defunct DOE beryllium vendors who were employed with these companies while they performed work for DOE. This change was made to ensure that workers who no longer have an employer to turn to for beryllium disease testing could receive this important screening. DOE will offer these individuals a blood test at no cost to check for beryllium sensitization. DOE will pay for both the costs of drawing the blood and the analysis of the blood. If a screened individual receives an abnormal test for beryllium sensitization, they can receive medical monitoring for beryllium disease through DOL's EEOICP.

427

Pinellas Former Construction Worker, Construction Worker Screening Projects  

Broader source: Energy.gov (indexed) [DOE]

Pinellas Former Construction Worker, Construction Worker Screening Pinellas Former Construction Worker, Construction Worker Screening Projects Pinellas Former Construction Worker, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Pinellas Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: 1-800-866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

428

FIELD SCREENING FOR HALOGENATED VOLATILE ORGANIC COMPOUNDS: THE NEW X-WAND HVOC SCREENING DEVICE  

SciTech Connect (OSTI)

Western Research Institute (WRI) has developed new methodology and a test kit to screen soil or water samples for halogenated volatile organic compounds (HVOCs) in the field. The technology has been designated the X-Wand{trademark} screening tool. The new device uses a heated diode sensor that is commonly used to detect leaks of refrigerants from air conditioners, freezers, and refrigerators. This sensor is selective to halogens. It does not respond to volatile aromatic hydrocarbons, such as those in gasoline, and it is not affected by high humidity. In the current work, the heated diode leak detectors were modified further to provide units with rapid response and enhanced sensitivity. The limit of detection for trichloroethylene TCE in air is 0.1 mg/m{sup 3} (S/N = 2). The response to other HVOCS relative to TCE is similar. Variability between sensors and changes in a particular sensor over time can be compensated for by normalizing sensor readings to a maximum sensor reading at 1,000 mg/m{sup 3} TCE. The soil TCE screening method was expanded to include application to water samples. Assuming complete vaporization, the detection limit for TCE in soil is about 1 ug/kg (ppb) for a 25-g sample in an 8-oz jar. The detection limit for TCE in water is about 1 ug/L (ppb) for a 25-mL sample in an 8-oz jar. This is comparable to quantitation limits of EPA GC/MS laboratory methods. A draft ASTM method for screening TCE contaminated soils using a heated diode sensor was successfully submitted for concurrent main committee and subcommittee balloting in ASTM Committee D 34 on Waste Management. The method was approved as ASTM D 7203-05, Standard Test Method for Screening Trichloroethylene (TCE)-Contaminated Soil Using a Heated Diode Sensor.

John F. Schabron; Susan S. Sorini; Joseph F. Rovani Jr

2006-03-01T23:59:59.000Z

429

Lung-Cancer Screening with Low-Dose Computed Tomography  

Science Journals Connector (OSTI)

...but complications of invasive testing were not. Across all three rounds of screening, 39% of the participants in the low-dose CT group had at least one positive result; more than 95% of these findings were falsely positive. Most patients with positive screening-test results required follow-up imaging... A large randomized trial showed that low-dose CT screening reduced the risk of lung-cancer death by 20% among long-time smokers. Recent guidelines support consideration of screening but with attention to the possibility of false positive results and associated risks.

Gould M.K.

2014-11-06T23:59:59.000Z

430

Combining in vivo and in silico screening for protein stability  

E-Print Network [OSTI]

Implications for the Protein Folding Code". Biochemistry 44(Proteolytic selection for protein folding using filamentousin vivo screening for protein folding and increased protein

Barakat, Nora Hisham

2007-01-01T23:59:59.000Z

431

Electric and Magnetic Screening Masses around the Deconfinement Transition  

E-Print Network [OSTI]

We report on the status of our study of gluon propagators and screening masses around the de- confining transition for pure SU(2) gauge theory in Landau gauge.

Attilio Cucchieri; Tereza Mendes

2012-01-29T23:59:59.000Z

432

HUD CHP GUIDE #2 - FEASIBILITY SCREENING FOR CHP IN MULTIFAMILY...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

(HUD's) 2002 Energy Action Plan includes an initiative to promote the use of combined heat and power (CHP) in multifamily housing. This 2009 guide "Feasibility Screening for...

433

Free film screening at Bradbury Science Museum September 7  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Free Film Screening At Bradbury Science Museum Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue: Dec. 2014 - Jan. 2015...

434

Health Fairs and Screenings - HPMC Occupational Health Services  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Wellness > Health Fairs and Screenings Health Education & Wellness Downloads & Patient Materials Health & Productivity Health Calculators & Logs Health Coaching Health Fairs and...

435

Crystallization screening: the influence of history on current practice  

Science Journals Connector (OSTI)

The rich history of crystallization and how that history influences current practices is described. The tremendous impact of crystallization screens on the field is discussed.

Luft, J.R.

2014-06-27T23:59:59.000Z

436

Screening effects in the electronoptical-phonon interaction  

Science Journals Connector (OSTI)

We show that recently reported [Alexandrov and Schrieffer, Phys. Rev. B 56, 13 731 (1997)] unusual hardening of optical phonons renormalized by the electron-phonon interaction is due to the neglect of screening effects. When the electron-ion interaction is properly screened, optical phonons soften in three dimensions. It is important that for short-wavelength optical phonons screening is static, while for long-wavelength optical phonons screening is dynamic. In two-dimensional and one-dimensional cases due to crossing of the nonperturbed optical mode with gapless plasmons, the spectrum of renormalized optical phononplasmon mode shows split momentum dependence.

Michael Reizer

2000-01-01T23:59:59.000Z

437

Medical Screening Protocol for the Former Worker Medical Screening Program U.S. Department of Energy, April 16, 2013  

Broader source: Energy.gov (indexed) [DOE]

4/16/13 4/16/13 MEDICAL SCREENING PROTOCOL FOR THE FORMER WORKER MEDICAL SCREENING PROGRAM U.S. DEPARTMENT OF ENERGY General Principles: 1) The purpose of the medical evaluation component of the U.S. Department of Energy (DOE) Former Worker Medical Screening Program (FWP) is to provide interested former workers with targeted testing to screen for selected adverse health effects potentially related to their work in DOE operations. The program does not test for all potentially work-related conditions; for example, screening for work- related musculoskeletal conditions is not included in the medical evaluation. 2) The following table is intended to identify work-related health outcomes of relevance to DOE workers for which there are screening tests that are reasonably likely to be effective and beneficial to program

438

Medical Screening Protocol for the Former Worker Medical Screening Program U.S. Department of Energy, April 16, 2013  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

4/16/13 4/16/13 MEDICAL SCREENING PROTOCOL FOR THE FORMER WORKER MEDICAL SCREENING PROGRAM U.S. DEPARTMENT OF ENERGY General Principles: 1) The purpose of the medical evaluation component of the U.S. Department of Energy (DOE) Former Worker Medical Screening Program (FWP) is to provide interested former workers with targeted testing to screen for selected adverse health effects potentially related to their work in DOE operations. The program does not test for all potentially work-related conditions; for example, screening for work- related musculoskeletal conditions is not included in the medical evaluation. 2) The following table is intended to identify work-related health outcomes of relevance to DOE workers for which there are screening tests that are reasonably likely to be effective and beneficial to program

439

FIELD SCREENING FOR HALOGENATED VOLATILE ORGANIC COMPOUNDS  

SciTech Connect (OSTI)

Western Research Institute (WRI) is continuing work toward the development of new screening methodology and a test kit to measure halogenated volatile organic compounds (VOCs) in the field. Heated diode and corona discharge sensors are commonly used to detect leaks of refrigerants from air conditioners, freezers, and refrigerators. They are both selective to the presence of halogens. In prior work, the devices were tested for response to carbon tetrachloride, heptane, toluene, and water vapors. In the current work, sensor response was evaluated with sixteen halogenated VOCs relative to carbon tetrachloride. The results show that the response of the various chlorinated VOCs is within an order of magnitude of the response to carbon tetrachloride for each of the sensors. Thus, for field screening a single response factor can be used. Both types of leak detectors are being further modified to provide an on-board LCD signal readout, which is related to VOC concentration. The units will be fully portable and will operate with 115-V line or battery power. Signal background, noise level, and response data on the Bacharach heated diode detector and the TIF corona discharge detector show that when the response curves are plotted against the log of concentration, the plot is linear to the upper limit for the particular unit, with some curvature at lower levels. When response is plotted directly against concentration, the response is linear at the low end and is curved at the high end. The dynamic ranges for carbon tetrachloride of the two devices from the lower detection limit (S/N=2) to signal saturation are 4-850 vapor parts per million (vppm) for the corona discharge unit and 0.01-70 vppm for the heated diode unit. Additional circuit modifications are being made to lower the detection limit and increase the dynamic response range of the corona discharge unit. The results indicate that both devices show potential utility for future analytical method development work toward the goal of developing a portable test kit for screening halogenated VOCs in the field.

John F. Schabron; Joseph F. Rovani, Jr.; Theresa M. Bomstad

2003-07-01T23:59:59.000Z

440

Electron Screening Effect on Stellar Thermonuclear Fusion  

E-Print Network [OSTI]

Key words Dense matter, stellar nucleosynthesis. We study the impact of plasma correlation effects on nonresonant thermonuclear reactions for various stellar objects, namely in the liquid envelopes of neutron stars, and the interiors of white dwarfs, low-mass stars, and substellar objects. We examine in particular the effect of electron screening on the enhancement of thermonuclear reactions in dense plasmas within and beyond the linear mixing rule approximation as well as the corrections due to quantum effects at high density. In addition, we examine some recent unconventional theoretical results on stellar thermonuclear fusions and show that these scenarios do not apply to stellar conditions. c ? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 1

K. -h. Spatschek; M. Bonitz; T. Klinger; U. Ebert; C. Franck; A. V. Keudell; D. Naujoks; M. Dewitz; A. Y. Potekhin; G. Chabrier

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Apparatus and method for radioactive waste screening  

SciTech Connect (OSTI)

An apparatus and method relating to screening radioactive waste are disclosed for ensuring that at least one calculated parameter for the measurement data of a sample falls within a range between an upper limit and a lower limit prior to the sample being packaged for disposal. The apparatus includes a radiation detector configured for detecting radioactivity and radionuclide content of the of the sample of radioactive waste and generating measurement data in response thereto, and a collimator including at least one aperture to direct a field of view of the radiation detector. The method includes measuring a radioactive content of a sample, and calculating one or more parameters from the radioactive content of the sample.

Akers, Douglas W.; Roybal, Lyle G.; Salomon, Hopi; Williams, Charles Leroy

2012-09-04T23:59:59.000Z

442

Cooling air duct and screen arrangement for an air cooled engine  

SciTech Connect (OSTI)

This patent describes a cooling air duct and screen arrangement for an air cooled engine which includes an improved cooling air system for ensuring a supply of relatively clean air for ingestion by the cooling shroud, which consists of: a vertical transverse baffle mounted to the frame and fitting closely against a forward top portion of the shroud and having an edge shaped complementary to and disposed at least closely adjacent the hood. An air duct is mounted to the frame and has an upright rear wall seated against the front of the shroud in an area surrounding the inlet. The air duct further has an upright front wall and a connecting wall joining respective side and bottom edges of the front and rear walls and cooperating therewith to define an upwardly facing opening. A screen is located forwardly of the baffle and has a top and front joined by opposite sides with the top and opposite sides having rear edges mounted against the baffle and with the opposite sides and front having bottom edges engaged with the air duct about the upwardly facing opening wherein the screen is mounted solely to the baffle by connection means including a vertical guide means provided on the forward side of the baffle and flange means formed on the screen and being vertically slidably received in the guide means.

Hoch, J.J.; Stricker, D.K.

1986-03-04T23:59:59.000Z

443

Screened thermonuclear reactions and predictive stellar evolution of detached double-lined eclipsing binaries  

E-Print Network [OSTI]

The low energy fusion cross sections of charged-particle nuclear reactions (and the respective reaction rates) in stellar plasmas are enhanced due to plasma screening effects. We study the impact of those effects on predictive stellar evolution simulations for detached double-lined eclipsing binaries. We follow the evolution of binary systems (pre-main sequence or main sequence stars) with precisely determined radii and masses from 1.1Mo to 23Mo (from their birth until their present state). The results indicate that all the discrepancies between the screened and unscreened models (in terms of luminosity, stellar radius, and effective temperature) are within the observational uncertainties. Moreover, no nucleosynthetic or compositional variation was found due to screening corrections. Therefore all thermonuclear screening effects on the charged-particle nuclear reactions that occur in the binary stars considered in this work (from their birth until their present state) can be totally disregarded. In other words, all relevant charged-particle nuclear reactions can be safely assumed to take place in a vacuum, thus simplifying and accelerating the simulation processes.

Theodore Liolios; Theocharis Kosmas

2005-07-06T23:59:59.000Z

444

STATEMENT OF CONSIDERATIONS REQUEST BY A123 SYSTEMS, INC. FOR AN ADVANCE WAIVER OF DOMESTIC AND  

Broader source: Energy.gov (indexed) [DOE]

1187, W(A)-2011-038, CH-1616 1187, W(A)-2011-038, CH-1616 The Petitioner, A123 Systems, Inc (A123) was awarded this cooperative agreement for the performance of work entitled, "High Throughput Fabrication of 10-Year PHEV Battery Electrodes". The purpose of the agreement is to develop advanced manufacturing technology for high-energy lithium ion batteries suitable for PHEV applications. This effort focuses speCifically on several unit operations used in electrode fabrication. By increasing the solids loading and stability of electrode slurry of the fabrication process, the electrode cost will be reduced through the decrease of drying time and the elimination of solvent emissions. Controlling the moisture content will primarily benefit electrode cycle life. Increasing the throughput of the coating/drying operation, this objective will

445

Former Worker Medical Screening Program 2012 Annual Report  

Broader source: Energy.gov (indexed) [DOE]

Published February 2013 Published February 2013 Pu Pu Publ b blis s ishe he hed d d Fe Fe Febr br brua ua u ry ry 2 201 013 3 FORMER WORKER MEDICAL SCREENING PROGRAM ANNUAL REPORT ANNUAL REPORT 2 0 1 2 STC STONETURN CONSULTANTS 2012 Former Worker Medical Screening Program * i Table of Contents Abbreviations ............................................................................................................................................iii Foreword .................................................................................................................................................... v Executive Summary .................................................................................................................................

446

Printing Your Monthly PTA Maintenance Screen Shannon Monahan Page 1  

E-Print Network [OSTI]

Printing Your Monthly PTA Maintenance Screen Shannon Monahan Page 1 Office of Postdoctoral Maintenance Screen. All starting points begin before the popup menu comes up. In Internet Explorer the Orientation to Landscape, and click OK. Print as needed to either your printer or to Adobe PDF (only works

Kay, Mark A.

447

2013 Former Worker Medical Screening Program Annual Report  

Broader source: Energy.gov [DOE]

The 2013 Annual Report presents a detailed overview of the accomplishments, progress, and future endeavors of the U.S. Department of Energy Former Worker Medical Screening Program. The report describes how the program is implemented, what organizations are involved in the medical screening efforts, and what the medical findings have been to date.

448

New algebraic constructions for pooling design in DNA library screening  

Science Journals Connector (OSTI)

Pooling design is an important mathematical tool in DNA library screening. It has been showed that using pooling design, the number of tests in DNA library screening can be greatly reduced. In this paper, we present some new algebraic constructions for pooling design.

Zengti Li; Suogang Gao; Hongjie Du; Yan Shi; Weili Wu

2010-01-01T23:59:59.000Z

449

Results of the material screening program of the NEXT experiment  

E-Print Network [OSTI]

The 'Neutrino Experiment with a Xenon TPC (NEXT)', intended to investigate neutrinoless double beta decay, requires extremely low background levels. An extensive material screening and selection process to assess the radioactivity of components is underway combining several techniques, including germanium gamma-ray spectrometry performed at the Canfranc Underground Laboratory; recent results of this material screening program are presented here.

Dafni, T; Bandac, I; Bettini, A; Borges, F I G M; Camargo, M; Carcel, S; Cebrian, S; Cervera, A; Conde, C A N; Diaz, J; Esteve, R; Fernandes, L M P; Fernandez, M; Ferrario, P; Ferreira, A L; Freitas, E D C; Gehman, V M; Goldschmidt, A; Gomez, H; Gomez-Cadenas, J J; Gonzalez-Diaz, D; Gutierrez, R M; Hauptman, J; Morata, J A Hernando; Herrera, D C; Iguaz, F J; Irastorza, I G; Labarga, L; Laing, A; Liubarsky, I; Lorca, D; Losada, M; Luzon, G; Mari, A; Martin-Albo, J; Martinez, A; Martinez-Lema, G; Miller, T; Monrabal, F; Monserrate, M; Monteiro, C M B; Mora, F J; Moutinho, L M; Vidal, J Munoz; Nebot-Guinot, M; Nygren, D; Oliveira, C A B; Perez, J; Aparicio, J L Perez; Renner, J; Ripoll, L; Rodriguez, A; Rodriguez, J; Santos, F P; Santos, J M F dos; Segui, L; Serra, L; Shuman, D; Simon, A; Sofka, C; Sorel, M; Toledo, J F; Torrent, J; Tsamalaidze, Z; Veloso, J F C A; Villar, J A; Webb, R C; White, J T; Yahlali, N

2014-01-01T23:59:59.000Z

450

Rocky Flats Former Construction Workers, Construction Worker Screening  

Broader source: Energy.gov (indexed) [DOE]

Rocky Flats Former Construction Workers, Construction Worker Rocky Flats Former Construction Workers, Construction Worker Screening Projects Rocky Flats Former Construction Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Rocky Flats Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Local Outreach Office: Dwayne Adkins 7510 W. Mississippi Ave., Suite 230 Lakewood, CO 80226 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica

451

Holographic screens in ultraviolet self-complete quantum gravity  

E-Print Network [OSTI]

In this paper we study the geometry and the thermodynamics of a holographic screen in the framework of the ultraviolet self-complete quantum gravity. To achieve this goal we construct a new static, neutral, non-rotating black hole metric, whose outer (event) horizon coincides with the surface of the screen. The space-time admits an extremal configuration corresponding to the minimal holographic screen and having both mass and radius equalling the Planck units. We identify this object as the space-time fundamental building block, whose interior is physically unaccessible and cannot be probed even during the Hawking evaporation terminal phase. In agreement with the holographic principle, relevant processes take place on the screen surface. The area quantization leads to a discrete mass spectrum. An analysis of the entropy shows that the minimal holographic screen can store only one byte of information while in the thermodynamic limit the area law is corrected by a logarithmic term.

Piero Nicolini; Euro Spallucci

2014-03-04T23:59:59.000Z

452

Screening in Thermonuclear Reaction Rates in the Sun  

E-Print Network [OSTI]

We evaluate the effect of electrostatic screening by ions and electrons on low-Z thermonuclear reactions in the sun. We use a mean field formalism and calculate the electron density of the screening cloud using the appropriate density matrix equation of quantum statistical mechanics. Because of well understood physical effects that are included for the first time in our treatment, the calculated enhancement of reaction rates does not agree with the frequently used interpolation formulae. Our result does agree, within small uncertainties, with Salpeter's weak screening formula. If weak screening is used instead of the commonly employed screening prescription of Graboske et al., the predicted $^8$B neutrino flux is increased by 7% and the predicted chlorine rate is increased by 0.4 SNU.

Andrei V. Gruzinov; John N. Bahcall

1998-01-20T23:59:59.000Z

453

Former Worker Medical Screening Program | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Former Worker Medical Screening Former Worker Medical Screening Program Former Worker Medical Screening Program The Former Worker Medical Screening Program (FWP) provides ongoing medical screening examinations, at no cost, to all former DOE Federal, contractor, and subcontractor workers who may be at risk for occupational diseases. The FWP is supported by the U.S. Department of Energy's (DOE) Office of Health, Safety and Security (HSS) and reflects our commitment to the health and safety of all DOE workers - past and present - who have served the Nation in its National security and other missions. The FWP was established following the issuance of the National Defense Authorization Act for Fiscal Year 1993 (PL 102-484), which called for DOE to assist workers with determining whether they had health issues related

454

High Performance Interconnect System Design for Future Chip Multiprocessors  

E-Print Network [OSTI]

constraints of power and area, and provide ultra low latencies and high throughput. In this research, we explore different techniques to design high performance NOC. First, existing NOCs mostly use Dimension Order Routing (DOR) to determine the route taken...

Wang, Lei

2013-05-02T23:59:59.000Z

455

Secure and Scalable Systems for Research Data Management  

E-Print Network [OSTI]

Recent years have witnessed extraordinary advancement in the data generation capacity of research tools such as mass spectrometry, genomic sequencing, digital imaging and other high throughput technologies. This has led to an enormous increase...

Walsh, Paul

2014-08-26T23:59:59.000Z

456

Coulomb screening in graphene with topological defects  

E-Print Network [OSTI]

We analyze the screening of an external Coulomb charge in gapless graphene cone, which is taken as a prototype of a topological defect. In the subcritical regime, the induced charge is calculated using both the Green's function and the Friedel sum rule. The dependence of the polarization charge on the Coulomb strength obtained from the Green's function clearly shows the effect of the conical defect and indicates that the critical charge itself depends on the sample topology. Similar analysis using the Friedel sum rule indicates that the two results agree for low values of the Coulomb charge but differ for the higher strengths, especially in the presence of the conical defect. For a given subcritical charge, the transport cross-section has a higher value in the presence of the conical defect. In the supercritical regime we show that the coefficient of the power law tail of polarization charge density can be expressed as a summation of functions which vary log periodically with the distance from the Coulomb imp...

Chakraborty, Baishali; Sen, Siddhartha

2015-01-01T23:59:59.000Z

457

Coulomb screening in graphene with topological defects  

E-Print Network [OSTI]

We analyze the screening of an external Coulomb charge in gapless graphene cone, which is taken as a prototype of a topological defect. In the subcritical regime, the induced charge is calculated using both the Green's function and the Friedel sum rule. The dependence of the polarization charge on the Coulomb strength obtained from the Green's function clearly shows the effect of the conical defect and indicates that the critical charge itself depends on the sample topology. Similar analysis using the Friedel sum rule indicates that the two results agree for low values of the Coulomb charge but differ for the higher strengths, especially in the presence of the conical defect. For a given subcritical charge, the transport cross-section has a higher value in the presence of the conical defect. In the supercritical regime we show that the coefficient of the power law tail of polarization charge density can be expressed as a summation of functions which vary log periodically with the distance from the Coulomb impurity. The period of variation depends on the conical defect. In the presence of the conical defect, the Fano resonances begin to appear in the transport cross-section for a lower value of the Coulomb charge. For both sub and supercritical regime we derive the dependence of LDOS on the conical defect. The effects of generalized boundary condition on the physical observables are also discussed.

Baishali Chakraborty; Kumar S. Gupta; Siddhartha Sen

2015-02-16T23:59:59.000Z

458

Preparation and screening of crystalline inorganic materials  

DOE Patents [OSTI]

Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc. Once prepared, these materials can be screened for useful properties including, for example, electrical, thermal, mechanical, morphological, optical, magnetic, chemical, or other properties. Thus, the present invention provides methods for the parallel synthesis and analysis of novel materials having useful properties.

Schultz, Peter G. (La Jolla, CA); Xiang, Xiaodong (Danville, CA); Goldwasser, Isy (Palo Alto, CA); Brice{hacek over (n)}o, Gabriel (Baldwin Park, CA); Sun, Xiao-Dong (Fremont, CA); Wang, Kai-An (Cupertino, CA)

2008-10-28T23:59:59.000Z

459

Combinatorial screening of inorganic and organometallic materials  

DOE Patents [OSTI]

Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc. Once prepared, these materials can be screened for useful properties including, for example, electrical, thermal, mechanical, morphological, optical, magnetic, chemical, or other properties. Thus, the present invention provides methods for the parallel synthesis and analysis of novel materials having useful properties.

Schultz, Peter G. (Oakland, CA); Xiang, Xiaodong (Alameda, CA); Goldwasser, Isy (Alameda, CA)

2002-01-01T23:59:59.000Z

460

Unified description of screened modified gravity  

Science Journals Connector (OSTI)

We consider modified gravity models driven by a scalar field whose effects are screened in high density regions due to the presence of nonlinearities in its interaction potential and/or its coupling to matter. Our approach covers chameleon, f(R) gravity, dilaton and symmetron models and allows a unified description of all these theories. We find that the dynamics of modified gravity are entirely captured by the time variation of the scalar field mass and its coupling to matter evaluated at the cosmological minimum of its effective potential, where the scalar field has sat since an epoch prior to big bang nucleosynthesis. This new parametrization of modified gravity allows one to reconstruct the potential and coupling to matter and therefore to analyze the full dynamics of the models, from the scale dependent growth of structures at the linear level to nonlinear effects requiring N-body simulations. This procedure is illustrated with explicit examples of reconstruction for chameleon, dilaton, f(R) and symmetron models.

Philippe Brax; Anne-Christine Davis; Baojiu Li; Hans A. Winther

2012-08-08T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Development of a screening method for drought tolerance in cotton seedlings  

E-Print Network [OSTI]

The key to an efficient screening method is the ability to screen large amounts of plant material in the shortest time possible. Unfortunately, due to the complexity of drought tolerance, a quick and effective screen for this trait has yet...

Longenberger, Polly Suzanne

2007-04-25T23:59:59.000Z

462

Simple Method for Screening Candida Species Isolates for the Presence of Secreted Proteinases: a Tool for the Prediction of Successful Inhibitory Treatment  

Science Journals Connector (OSTI)

...developed a screening system based on a solid...indicator. Using this system, we assessed...an appropriate tool for the rapid and reliable assessment of Sap production...the Auxacolor system [Bio-Rad...4 or 4.5. A steam-sterilizable...

Ji Dostl; Petr Hamal; Libue Pavl?kov; Milan Sou?ek; Tom Ruml; Iva Pichov; Olga Hrukov-Heidingsfeldov

2003-02-01T23:59:59.000Z

463

Global health response more accurate with automated influenza surveillance  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Global health response more accurate with automated influenza Global health response more accurate with automated influenza surveillance Global health response more accurate with automated influenza surveillance Public health officials will be able to determine whether an outbreak of an infectious disease comes from a pandemic strain or one less virulent. January 31, 2011 Lance Green of LANL tests an earlier version of a modular laboratory like the ones that will be part of the High-Throughput Laboratory Network Lance Green of LANL tests an earlier version of a modular laboratory like the ones that will be part of the High-Throughput Laboratory Network-a series of compact, self-contained, automated systems for surveillance and screening of potential pandemic strains of influenza and other deadly infectious diseases.

464

Smallscale and automatable highthroughput compositional analysis of biomass  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Small-Scale Small-Scale and Automatable High-Throughput Compositional Analysis of Biomass Jaclyn D. DeMartini, Michael H. Studer, Charles E. Wyman Center for Environmental Research and Technology, Bourns College of Engineering, University of California Riverside, 1084 Columbia Avenue, Riverside, California 92507; telephone: 951-781-5703; fax: 951-781-5790; e-mail: charles.wyman@ucr.edu Received 26 May 2010; revision received 26 August 2010; accepted 3 September 2010 Published online 9 September 2010 in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/bit.22937 ABSTRACT: Conventional wet chemistry methods to deter- mine biomass composition are labor- and time-intensive and require larger amounts of biomass (300 mg) than is often available. To overcome these limitations and to sup- port a high-throughput pretreatment and hydrolysis (HTPH) screening system,

465

Former Worker Medical Screening Program Related Documents & Links |  

Broader source: Energy.gov (indexed) [DOE]

Former Former Worker Medical Screening Program Related Documents & Links Former Worker Medical Screening Program Related Documents & Links Related Documents & Links Beryllium Information-ORISE Chronic Beryllium Disease Information-National Jewish Health Department of Energy Human Subjects Protection Program DOE Covered Facilities Database Department of Labor Energy Employees Occupational Illness Compensation Program (EEOICP) Department of Labor EEOICP - Upcoming Events Department of Labor Office of the Ombudsman for EEOICPA NIOSH Advisory Board and Public Meetings NIOSH Division of Compensation Analysis and Support Project Websites Building Trades National Medical Screening Program Medical Exam Program for Former Workers at Los Alamos National Laboratory

466

Screening model for nanowire surface-charge sensors in liquid  

E-Print Network [OSTI]

The conductance change of nanowire field-effect transistors is considered a highly sensitive probe for surface charge. However, Debye screening of relevant physiological liquid environments challenge device performance due to competing screening from the ionic liquid and nanowire charge carriers. We discuss this effect within Thomas-Fermi and Debye-Huckel theory and derive analytical results for cylindrical wires which can be used to estimate the sensitivity of nanowire surface-charge sensors. We study the interplay between the nanowire radius, the Thomas-Fermi and Debye screening lengths, and the length of the functionalization molecules. The analytical results are compared to finite-element calculations on a realistic geometry.

Martin H. Sorensen; Niels Asger Mortensen; Mads Brandbyge

2007-08-17T23:59:59.000Z

467

E-Print Network 3.0 - applied cancer screening Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

cancer screening Search Powered by Explorit Topic List Advanced Search Sample search results for: applied cancer screening Page: << < 1 2 3 4 5 > >> 1 Summer Internship Results...

468

E-Print Network 3.0 - acsrb cancer screening Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

cancer screening Search Powered by Explorit Topic List Advanced Search Sample search results for: acsrb cancer screening Page: << < 1 2 3 4 5 > >> 1 Summer Internship Results...

469

E-Print Network 3.0 - anti glare screens Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HEALTH & SAFETY PROCEDURE USE OF DISPLAY SCREEN EQUIPMENT Summary: ) to reduce glare vi. software appropriate for the tasks performed vii. screen: stable image, adjustable... NERC...

470

E-Print Network 3.0 - attend cervical screening Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

screenings for women described... Newborns Screening for hearing loss, hypothyroidism, sickle cell disease and phenylketonuria (PKU Source: Ghajar, Afshin J. - School of...

471

E-Print Network 3.0 - alternative screening devices Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

blindness, mobile devices, touch screens, multi-touch interaction... in touch screen interfaces, as seen in ... Source: Anderson, Richard - Department of Computer Science and...

472

Discovery of Photocatalysts for Hydrogen Production  

SciTech Connect (OSTI)

This project for DOE was designed to address these materials-related issues through a combination of high-throughput screening of semiconductor candidates and theoretical modeling of nanostructures. High-throughput screening is an effective and economical way to examine a large number of candidates and identify those worthy of further study. Unfortunately, in the course of this project, we discovered no semiconductor candidates that can meet the DOEs stringent requirements for an economically feasible photoelectrochemical process. However, some of our results indicated that several systems may have potential if further optimized. In particular, the published theoretical modeling work indicates that core-shell nanorod structures, if properly engineered, have the potential to overcome the shortfalls of current semiconductors. Although the synthesis of the designed core-shell nanorod structures proved to be beyond the current capabilities of our laboratories, recent advances in the synthesis of core-shell nanorod structures imply that the designed structures can be synthesized. SRI is confident that once these materials are made they will validate our models and lead to economical and environmentally friendly hydrogen from sunlight and water. The high-throughput photolysis analysis module developed at SRI will also have utility in applications such as identifying catalysts for photo-assisted chemical detoxification, as well as non-photolytic applications such as hydrogen storage, which can take advantage of the ability of the analysis module to monitor pressure over time.

D. Brent MacQueen

2006-10-01T23:59:59.000Z

473

Screening-level approach for estimating contaminant export from tributaries  

SciTech Connect (OSTI)

The in-place pollutant export model (IPX) is a screening-level model for estimating contaminant export from tributaries with contaminated sediments to receiving waterbodies. IPX is a modified version of the USEPA`s WASP4 modeling framework. IPX synthesizes sediment transport processes for sediment aging, decreased sediment resuspendability with increasing age, and resuspension of freshly deposited sediments as a function of water velocity, into an expanded WASP4 contaminant transport and fate chassis while retaining the computational flexibility of the original framework. These process descriptions are needed to accurately simulate contaminant transport and substantially improve the framework for application to tributary systems subject to significant deposition and resuspension events. The potential for applying IPX is broad; water quality impairments attributable to contaminated sediments are widespread due to discharges from industry, agriculture, and mining and ore processing. IPX has been successfully applied to the upper and lower Fox River in Wisconsin, and the Buffalo and Oswego Rivers in New York, all impaired by contaminated sediments.

Velleux, M. [Wisconsin Dept. of Natural Resources, Madison, WI (United States); Gailani, J. [Army Corps of Engineers, Vicksburg, MS (United States); Endicott, D. [EPA Large Lakes Research Station, Grosse Ile, MI (United States)

1996-06-01T23:59:59.000Z

474

Renewable Energy Resource Maps and Screening Tools | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Resource Maps Resource Maps and Screening Tools Renewable Energy Resource Maps and Screening Tools October 7, 2013 - 9:42am Addthis Renewable energy resources are available across the United States but vary greatly depending on exact location and micro-climate. This page outlines renewable energy resource maps and screening tools to help Federal agencies assess the viability of on-site renewable energy projects. Before initiating a project, resources in your area must be measured and verified. Resource maps and screening tools are a good start, but it is important to consult an expert for a professional evaluation before implementing renewable energy projects. Resource Maps The U.S. Department of Energy (DOE) and its National Renewable Energy Laboratory compiled the following renewable energy resource maps.

475

Outreach (Former Worker Medical Screening Program (FWP) | Department of  

Broader source: Energy.gov (indexed) [DOE]

Outreach (Former Worker Medical Screening Program (FWP) Outreach (Former Worker Medical Screening Program (FWP) Outreach (Former Worker Medical Screening Program (FWP) Outreach: Identify and Notify Eligible DOE Workers About FWP Medical Screening Services All former DOE Federal, contractor, and subcontractor employees from all facilities are eligible to participate in the program. Although the historical best estimate for the population of former workers who are entitled to receive medical evaluations under the FWP is upwards of 600,000 individuals, the precise number of workers remains unknown. Most of the FWP projects use multiple outreach methods to increase the visibility of the program in communities surrounding DOE sites and to notify potentially eligible DOE workers about the availability of FWP services. These methods are three-fold: 1) roster-based, 2)

476

Pantex, Former Production Workers Screening Projects | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Pantex, Former Production Workers Screening Projects Pantex, Former Production Workers Screening Projects Pantex, Former Production Workers Screening Projects Project Name: Former Pantex Worker Medical Surveillance Program Covered DOE Site: Pantex Worker Population Served: All Workers Principal Investigator: Arthur Frank, MD, MPH Toll-free Telephone: (888) 378-8939 Local Medical Clinics: WTAMU Health Partners Clinic 4400 S. Washington Street Amarillo, TX 79110 Texas Diagnostic Imaging Center (X-rays only) 1000 Coulter Drive Amarillo, TX 79106 Former workers at risk from exposures while working at Pantex are offered a free medical screening. This project is carried out by Drexel University School of Public Health in conjunction with the University of Texas Health Science Center at Tyler. Workers from this site who do not live in close proximity to the above

477

In silico screening of carbon-capture materials | Center for...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

In silico screening of carbon-capture materials Previous Next List L.-C. Lin, A. H. Berger, R. L. Martin, J. Kim, J. A. Swisher, K. Jariwala, C. H. Rycroft, A. S. Bhown, M. W....

478

DNA Library Screening, Pooling Design and Unitary Spaces  

Science Journals Connector (OSTI)

Pooling design is an important research topic in bio- informatics due to its wide applications in molecular biology, especially DNA library screening. In this paper, with unitary spaces over finite fields, we pre...

Suogang Gao; Zengti Li; Jiangchen Yu

2009-01-01T23:59:59.000Z

479

Magnetic and electric screening masses from Polyakov-loop correlations  

E-Print Network [OSTI]

Screening properties of the quark gluon plasma are studied from Polyakov-loop correlation in lattice QCD simulations with two flavors of improved Wilson quarks at temperatures $T/\\Tpc \\simeq 1$--4 where $\\Tpc$ is the pseudocritical temperature. Using the Euclidean-time reflection symmetry and the charge conjugation symmetry, we introduce various types of Polyakov-loop correlation functions and extract screening masses in magnetic and electric sectors. We find that the temperature dependence of the screening masses are well described by the weak coupling expansion. We also find that a ratio of the screening masses in the electric sector to the magnetic sector shows qualitative agreement with a prediction from the dimensionally-reduced effective field theory and the N=4 supersymmetric Yang-Mills theory at $1.3 < T/\\Tpc < 3$.

Y. Maezawa; S. Aoki; S. Ejiri; T. Hatsuda; N. Ishii; K. Kanaya; N. Ukita; T. Umeda

2008-11-04T23:59:59.000Z

480

2013 Former Worker Medical Screening Program Annual Report  

Broader source: Energy.gov [DOE]

2013 Former Worker Medical Screening Program (FWP) Annual Report highlighting the accomplishments of this program, which provides critical services to those who served and sacrificed through their work in the Department and its predecessor agencies.

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Accelerator-Driven Neutron Source for Cargo Screening  

E-Print Network [OSTI]

Accelerator-Driven Neutron Source for Cargo Screening 1 B.A.The design of an accelerator-driven neutron source isQuadrupole (RFQ) accelerator and a neutron production gas

2006-01-01T23:59:59.000Z

482

Stochastic dominance for project screening and selection under uncertainty  

E-Print Network [OSTI]

At any given moment, engineering and chemical companies have a host of projects that they are either trying to screen to advance to the next stage of research or select from for implementation. These choices could range ...

Adeyemo, Adekunle M

2013-01-01T23:59:59.000Z

483

FREE FILM SCREENING AND DISCUSSION Abstract from Jezebel Productions  

E-Print Network [OSTI]

FREE FILM SCREENING AND DISCUSSION Abstract from Jezebel Productions: "No Dinosaurs in Heaven charge: free and open to the public. THURSDAY OCTOBER 27, 2011 7:00 PM Mackey Auditorium Ruby Gerontology

de Lijser, Peter

484

Appendix SCR: Feature, Event, and Process Screening for PA  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary of New Information SCR-4.1.3.1.1.3 Screening Argument SCR-4.1.3.2 Fracture Development SCR-4.1.3.2.1 FEP Number: N8 FEP Title: Formation of Fractures...

485

Iowa Army Ammunition Plant, Former Production Workers Screening Projects |  

Broader source: Energy.gov (indexed) [DOE]

Plant, Former Production Workers Screening Plant, Former Production Workers Screening Projects Iowa Army Ammunition Plant, Former Production Workers Screening Projects Project Name: Medical Monitoring of Former Atomic Weapons Workers at the Iowa Army Ammunition Plant (IAAP) in Burlington, Iowa Covered DOE Site: IAAP Worker Population Served: All Line 1/Division B Workers Principal Investigator: Laurence Fuortes, MD Toll-free Telephone: (866) 282-5818 Local Medical Clinics: University of Iowa Hospitals and Clinics 200 Hawkins Drive Iowa City, IA 52242 Henry County Health Center 407 South White Street Mt. Pleasant, IA 62641 Great River Medical Center 1221 S. Gear Avenue West Burlington, IA 52655 Website: http://cph.uiowa.edu/iowafwp/ This project is intended to screen for occupational health conditions among

486

AVIAN AND BAT SCREENING ANALYSIS AND HABITAT CHARACTERIZATION  

Broader source: Energy.gov (indexed) [DOE]

AVIAN AND BAT SCREENING ANALYSIS AVIAN AND BAT SCREENING ANALYSIS AND HABITAT CHARACTERIZATION Barr Engineering Company UMore Park Research Wind Turbine Dakota County, Minnesota June 2010 Prepared For: Barr Engineering Company 4700 West 77 th St. Minneapolis, MN 55435 Prepared By: 1900 Wazee Street, Suite 200 Denver, Colorado 80202 Phone: (720) 330-7280 Fax: (303) 458-5701 www.nrcdifference.com NRC Project # 0010-0110-01

487

Systematic quantum corrections to screening in thermonuclear fusion  

E-Print Network [OSTI]

We develop a series expansion of the plasma screening length away from the classical limit in powers of $\\hbar^{2}$. It is shown that the leading order quantum correction increases the screening length in solar conditions by approximately 2% while it decreases the fusion rate by approximately $ 0.34%$. We also calculate the next higher order quantum correction which turns out to be approximately 0.05%.

Chitanvis, S M

2006-01-01T23:59:59.000Z

488

A procedure to screen cucumber for salt tolerance  

E-Print Network [OSTI]

A PROCEDURE TO SCREEN CUCUMBER FOR SALT TOLERANCE A Thesis by LEONARD FRANK YOURMAN Submitted to the Graduate College of Texas A1IM University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE August 1979 Major... Subject: Horticulture A PROCEDURE TO SCREEN CUCUMBER FOR SALT TOLERANCE A Thesis by LEONARD FRANK VOURMAN Approved as to style and content by: (Chairman of Committee) (Head of Department) (Member) (Member) 0ugust 1979 ABSTRACT A Procedure...

Yourman, Leonard Frank

2012-06-07T23:59:59.000Z

489

A screening technique for salt tolerance in onion  

E-Print Network [OSTI]

A SCREENING TECHNIQUE FOR SALT TOLERANCE IN ONION A Thesis by MARY JORDAN WANNAMAKER Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE August 1985 Major... Subject: Horticulture A SCREENING TECHNIQUE FOR SALT TOLERANCE IN ONION A Thesis by NARY JORDAN WANNAMAKER Approved as to style and content by: Leonard M. Pike (Chairma f Cp 'ttee) 'eg C. Cobb (Member) Ron Newton (Member) . Grant Vest (Head...

Wannamaker, Mary Jordon

2012-06-07T23:59:59.000Z

490

Systematic quantum corrections to screening in thermonuclear fusion  

E-Print Network [OSTI]

We develop a series expansion of the plasma screening length away from the classical limit in powers of $\\hbar^{2}$. It is shown that the leading order quantum correction increases the screening length in solar conditions by approximately 2% while it decreases the fusion rate by approximately $ 0.34%$. We also calculate the next higher order quantum correction which turns out to be approximately 0.05%.

Shirish M. Chitanvis

2006-06-13T23:59:59.000Z

491

Pacific Northwest Laboratory`s Lighting Technology Screening Matrix  

SciTech Connect (OSTI)

Pacific Northwest Laboratory has developed the Lighting Technology Screening Matrix (LTSM), a software tool to evaluate alternative lighting retrofit technologies according to life-cycle cost. The LTSM can be used to evaluate retrofits for most configurations of fluorescent, incandescent, high- and low-pressure sodium, metal halide, mercury vapor, and exit lighting systems for any level of operation, electricity price, discount rate, and utility rebate. This tool was developed, in support of the Federal Relighting Initiative as part of the Department of Energy`s Office of Federal Energy Management Program (DOE/FEMP) to assist federal government facilities in their efforts to comply with the 10 CFR 436 mandated life-cycle costing for energy equipment investments. The LTSM has been used in the course of seven site modernization projects. These projects consisted of determining the cost-effective, energy-efficiency potential at military installations. Each project treated the entire military installation as an integrated system, proposed a large number of potential efficiency projects affecting all end-uses and fuel types, and analyzed the cost-effectiveness of each project. The LTSM was used for the lighting portion of these projects. Lighting was, overall, one of the major areas of potential efficiency improvements, accounting for over 30% of the cost-effective resource. Altogether over $43 million worth of cost-effective efficiency investments were identified, worth an estimated $6 million annually in energy, demand, and operations and maintenance (O&M) savings. This paper describes the LTSM and demonstrates its application in a case study at one of the federal installations analyzed.

Harris, L.R. [USDOE, Washington, DC (United States); Stucky, D.J.; Dirks, J.A.; Schultz, R.W.; Shankle, S.A.; Richman, E.E.; Purcell, C.W. [Pacific Northwest Lab., Richland, WA (United States)

1994-04-01T23:59:59.000Z

492

Calcining process emission screening test for polychlorinated dibenzodioxins  

SciTech Connect (OSTI)

Since 1963, the Idaho Chemical Processing Plant (ICPP) at the Idaho National Engineering Laboratory has been using fluidized-bed technology to convert high-level radioactive liquid waste into a granular solid for interim storage before eventual long-term storage. The calcining process uses kerosene, oxygen, air and a cooling jacket to maintain the temperature of the fluidized bed at approximately 400 C. The solids are moved to storage bins and the combustion gases and fine particles are swept from the bed to an atmospheric protection system. This atmospheric protection system includes a cyclone to collect larger particles; a nitric acid scrubber to cool gases and collect small particles; a condenser to reduce water content; silica gel beds to adsorb volatile ruthenium, water, and hydrocarbons; and a series of high efficiency particulate air (HEPA) filters to collect minute particles. The calcination process solidifies waste solutions containing molar levels of acid, nitrate, fluoride, zirconium, aluminum, iron, boron, and cadmium; minor levels (<0.1%) of various fission products and organics; and trace levels (<50 ppm) of chloride and sulfate. Because the process burns kerosene in the presence of other organics and chloride salts; the calciner was considered a potential production source of polychlorinated dibenzo-p-dioxins (PCDD). Therefore, it was necessary to determine if PCDD were being released from the calcination process. Because a gas chromatograph mass spectrometer (GC-MS) and PCDD standards were not available, a screening procedure using two gas chromatographs with electron capture detectors and no PCDD calibration standards was developed.

Hartenstein, S.D.

1993-08-01T23:59:59.000Z

493

Power System Extreme Event Detection: The Vulnerability Frontier  

E-Print Network [OSTI]

Contingencies in Electric Power Networks, proceedings ofthe North American Power Symposium, Ames, IA, OctoberScreening in Electric Power Systems, submitted to the IEEE

Lesieutre, Bernard C.; Pinar, Ali; Roy, Sandip

2007-01-01T23:59:59.000Z

494

National Depression Screening Day: October 10th Come to National Depression Screening Day (NDSD) on Thursday, October 10th from  

E-Print Network [OSTI]

. If necessary, appropriate referrals can be made, and participants may also find information on depression, and provides individuals with feedback, referrals, and resources upon completion. KSU's online screening can

Khan, Javed I.

495

Distributed PV Interconnection Screening Procedures and Online...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and has been involved in a variety of removable technologies including load hydro, landfill gas, floor air conditioning, and sterling systems. We also have Jeff Healion who is the...

496

Screening for metabolic syndrome risk factors in mestizo, tarahumara and mennonite scholars from Chihuahua Mexico  

Science Journals Connector (OSTI)

To screen for MS risk factors among mestizo, tarahumara and mennonite teenagers from Chihuahua, Mexico.

I Leal-Berumen; V Santana-Rodriguez; P Hernndez-Rodrguez

2012-06-01T23:59:59.000Z

497

Van der Meulen and Brandsma Februari 2007 Thermometer Screen Intercomparison in De Bilt (the  

E-Print Network [OSTI]

conditions during a 6- year field experiment in De Bilt (the Netherlands). The comparison comprised two versions of an aspi- rated Young screen, 4 naturally ventilated round-shaped multi-plate screens (KNMI, Vaisala, Young, Socrima), a slightly aspirated version of the KNMI screen, a synthetic Stevenson screen

Haak, Hein

498

HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage  

Broader source: Energy.gov [DOE]

Presentation for the high temperature combinatorial screening for high capacity hydrogen storage meeting

499

John Day Fish Passage and Screening; 2002 Annual Report.  

SciTech Connect (OSTI)

This project is necessary to insure that replacement of fish screening devices and fishways meet current NMFS design criteria for the protection of all salmonid life stages. The mission of the fish passage program in Northeast Oregon is to protect and enhance fish populations by assisting private landowners, public landowners, irrigation districts and others by maintaining fish screening devices and fishways. These facilities reduce or eliminate fish loss associated with irrigation withdrawals, and as a result insure fish populations are maintained for enjoyment by present and future generations. Assistance is provided through state and federal programs. This can range from basic technical advice to detailed construction, fabrication and maintenance of screening and passage facilities. John Day screens personnel identified 50 sites for fish screen replacement, and one fish passage project. These sites are located in critical spawning, rearing and migration areas for spring chinook, summer steelhead and bull trout. All projects were designed and implemented to meet current NMFS criteria. It is necessary to have a large number of sites identified due to changes in weather, landowner cooperation and access issues that come up as we try and implement our goal of 21 completed projects.

Hartlerode, Ray; Dabashinsky, Annette (Oregon Department of Fish and Wildlife, Portland, OR); Allen, Steve (Oregon Department of Fish and Wildlife, John Day, OR)

2003-01-28T23:59:59.000Z

500

Yakima River Basin Phase II Fish Screen Evaluations, 2003  

SciTech Connect (OSTI)

In 2003, the Pacific Northwest National Laboratory (PNNL) evaluated 23 Phase II fish screen sites in the Yakima River Basin as part of a multi-year project for the Bonneville Power Administration on the effectiveness of fish screening devices. PNNL collected data to determine whether velocities in front of the screens and in the bypasses met the Nation Oceanic and Atmospheric Administration Fisheries (NOAA Fisheries, formerly the National Marine Fisheries Service (NMFS)) criteria to promote safe and timely fish passage. In addition, PNNL conducted underwater video surveys to evaluate the environmental and operational conditions of the screen sites with respect to fish passage. Based on evaluations in 2003, PNNL concluded that: (1) In general, water velocity conditions at the screen sites met fish passage criteria set by the National Oceanic and Atmospheric Administration Fisheries. (2) Conditions at most facilities would be expected to provide for safe juvenile fish passage. (3) Conditions at some facilities indicate that operation and/or maintenance should be modified to improve juvenile fish passage conditions. (4) Automated cleaning brushes generally functioned properly; chains and other moving parts were typically well greased and operative. (5) Removal of sediment buildup and accumulated leafy and woody debris could be improved at some sites.

Vucelick, Jessica A.; McMichael, Geoffrey A.; Chamness, Mickie A.

2004-05-01T23:59:59.000Z