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Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

High-Throughput Screening Techniques  

NLE Websites -- All DOE Office Websites (Extended Search)

Throughput Throughput Screening Techniques for Biomass Conversion Stephen R. Decker & Roman Brunecky & Melvin P. Tucker & Michael E. Himmel & Michael J. Selig Published online: 14 October 2009 # US Government 2009 Abstract High-throughput (HTP) screening of biomass or biomass-degrading enzymes, regardless of the desired outcome, is fraught with obstacles and challenges not typically faced in more traditional biotechnology. The enzyme systems are complex and synergistic and the substrate is highly heterogeneous, insoluble, and difficult to dispense. Digestions are often carried out for days at temperatures of 50°C or higher, leading to significant challenges regarding evaporation control in small well volumes. Furthermore, it is often desirable to condition or "pretreat" the biomass at extreme temperatures and/or pH to enhance enzyme digestibility.

2

High-throughput in vivo vertebrate screening  

E-Print Network (OSTI)

We demonstrate a high-throughput platform for cellular-resolution in vivo chemical and genetic screens on zebrafish larvae. The system automatically loads zebrafish from reservoirs or multiwell plates, and positions and ...

Pardo-Martin, Carlos

3

High-Throughput Pretreatment and Hydrolysis Systems for Screening Biomass Species in Aqueous Pretreatment of Plant Biomass  

NLE Websites -- All DOE Office Websites (Extended Search)

High-throughput High-throughput Pretreatment and Hydrolysis Systems for Screening Biomass Species in Aqueous Pretreatment of Plant Biomass Jaclyn D. DeMartini 1,2,3,Ã and Charles E. Wyman 1,2,3 1 Department of Chemical and Environmental Engineering, University of California, Riverside, USA 2 Center for Environmental Research and Technology, University of California, Riverside, USA 3 BioEnergy Science Center, Oak Ridge, USA 22.1 Introduction: The Need for High-throughput Technologies The primary barrier to low-cost biological conversion of lignocellulosic biomass to renewable fuels and chemicals is plant recalcitrance, that is to say, resistance of cell walls to deconstruction by enzymes or microbes [1,2]. However, the discovery and use of biomass species with reduced recalcitrance, when com- bined with optimized pretreatment processes and enzyme mixtures, could potentially

4

High throughput protein production screening  

DOE Patents (OSTI)

Methods, compositions, and kits for the cell-free production and analysis of proteins are provided. The invention allows for the production of proteins from prokaryotic sequences or eukaryotic sequences, including human cDNAs using PCR and IVT methods and detecting the proteins through fluorescence or immunoblot techniques. This invention can be used to identify optimized PCR and WT conditions, codon usages and mutations. The methods are readily automated and can be used for high throughput analysis of protein expression levels, interactions, and functional states.

Beernink, Peter T. (Walnut Creek, CA); Coleman, Matthew A. (Oakland, CA); Segelke, Brent W. (San Ramon, CA)

2009-09-08T23:59:59.000Z

5

Robust regression for high throughput drug screening  

Science Conference Proceedings (OSTI)

Effective analysis of high throughput screening (HTS) data requires automation of dose-response curve fitting for large numbers of datasets. Datasets with outliers are not handled well by standard non-linear least squares methods, and manual outlier ... Keywords: Agonist activity, Dose-response curve, HTS, IRLS, M-estimation, Robust regression

Igor Fomenko; Mark Durst; David Balaban

2006-04-01T23:59:59.000Z

6

Engineering of a high-throughput screening system to identify cellulosic biomass, pretreatments, and enzyme formulations that enhance sugar release  

NLE Websites -- All DOE Office Websites (Extended Search)

Engineering Engineering of a High-Throughput Screening System to Identify Cellulosic Biomass, Pretreatments, and Enzyme Formulations That Enhance Sugar Release Michael H. Studer, Jaclyn D. DeMartini, Simone Brethauer, Heather L. McKenzie, Charles E. Wyman Chemical and Environmental Engineering Department, Center for Environmental Research and Technology, Bourns College of Engineering, University of California Riverside, 1084 Columbia Avenue, Riverside, California 92507; telephone: þ951-781-5791; fax: þ951-781-5790; e-mail: charles.wyman@ucr.edu Received 7 April 2009; revision received 21 August 2009; accepted 31 August 2009 Published online 3 September 2009 in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/bit.22527 ABSTRACT: The recalcitrance of cellulosic biomass, the only abundant, sustainable feedstock for making liquid fuels, is a primary

7

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

NLE Websites -- All DOE Office Websites (Extended Search)

Workshop HIGH THROUGHPUTCOMBINATORIAL SCREENING OF HYDROGEN STORAGE MATERIALS June 26, 2007 Tom Boussie Symyx Technologies Symyx develops and applies proprietary high-throughput...

8

Development and optimization of high-throughput zebrafish screening platform  

E-Print Network (OSTI)

The high-throughput zebrafish screening platform is a revolutionary tool that enables subcellular precision in vivo whole animal screening of Danio Rerio. It can perform laser surgery and/or imaging in less than twenty ...

Koo, Bryan Kyo

2010-01-01T23:59:59.000Z

9

First principles high throughput screening of oxynitrides for water-splitting photocatalysts  

E-Print Network (OSTI)

In this paper, we present a first principles high throughput screening system to search for new water-splitting photocatalysts. We use the approach to screen through nitrides and oxynitrides. Most of the known photocatalytic ...

Wu, Yabi

2013-01-01T23:59:59.000Z

10

High-throughput vertebrate total analysis/screening platform  

E-Print Network (OSTI)

High-throughput screening (HTS) is seen as one of the most promising technologies to facilitate biomedical studies and pharmaceutical discoveries. Although large varieties of in vitro HTS technologies have opened great ...

Chang, Tsung-Yao, Ph. D. Massachusetts Institute of Technology

2012-01-01T23:59:59.000Z

11

Grid-enabled high throughput virtual screening  

Science Conference Proceedings (OSTI)

Large scale grids for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale virtual docking within the framework of the WISDOM initiative against ... Keywords: avian influenza, large scale grids, malaria, virtual screening

Nicolas Jacq; Vincent Breton; Hsin-Yen Chen; Li-Yung Ho; Martin Hofmann; Hurng-Chun Lee; Yannick Legr; Simon C. Lin; Astrid Maa; Emmanuel Medernach; Ivan Merelli; Luciano Milanesi; Giulio Rastelli; Matthieu Reichstadt; Jean Salzemann; Horst Schwichtenberg; Mahendrakar Sridhar; Vinod Kasam; Ying-Ta Wu; Marc Zimmermann

2007-01-01T23:59:59.000Z

12

High throughput optical sensor arrays for drug screening  

E-Print Network (OSTI)

In the world of drug discovery, high throughput whole cell assays are a critical step in discovering therapeutically relevant drug compounds [1]. This report details the development of several novel sensor systems capable ...

Harjes, Daniel I

2006-01-01T23:59:59.000Z

13

Directed Enzyme Evolution and High-Throughput Screening  

E-Print Network (OSTI)

3 Directed Enzyme Evolution and High-Throughput Screening Michael J. McLachlan,1 Ryan P. Sullivan2, the tailoring of an enzyme can still be accomplished through the second route: directed evolution. Biocatalysis John Wiley & Sons Asia (Pte) Ltd. ISBN: 978-0-470-82314-9 #12;Directed evolution is the general term

Zhao, Huimin

14

High Throughput Pretreatment and Enzyme Hydrolysis of Biomass: Screening Recalcitrance in Large Sample Populations (Presentation)  

DOE Green Energy (OSTI)

Presentation on the execution of the first high-throughput thermochemical pretreatment/enzyme digestion pipeline for screening biomass for recalcitrance.

Decker, S. R.

2010-10-01T23:59:59.000Z

15

Advances in High Throughput Screening of Biomass Recalcitrance (Poster)  

DOE Green Energy (OSTI)

This was a poster displayed at the Symposium. Advances on previous high throughput screening of biomass recalcitrance methods have resulted in improved conversion and replicate precision. Changes in plate reactor metallurgy, improved preparation of control biomass, species-specific pretreatment conditions, and enzymatic hydrolysis parameters have reduced overall coefficients of variation to an average of 6% for sample replicates. These method changes have improved plate-to-plate variation of control biomass recalcitrance and improved confidence in sugar release differences between samples. With smaller errors plant researchers can have a higher degree of assurance more low recalcitrance candidates can be identified. Significant changes in plate reactor, control biomass preparation, pretreatment conditions and enzyme have significantly reduced sample and control replicate variability. Reactor plate metallurgy significantly impacts sugar release aluminum leaching into reaction during pretreatment degrades sugars and inhibits enzyme activity. Removal of starch and extractives significantly decreases control biomass variability. New enzyme formulations give more consistent and higher conversion levels, however required re-optimization for switchgrass. Pretreatment time and temperature (severity) should be adjusted to specific biomass types i.e. woody vs. herbaceous. Desalting of enzyme preps to remove low molecular weight stabilizers and improved conversion levels likely due to water activity impacts on enzyme structure and substrate interactions not attempted here due to need to continually desalt and validate precise enzyme concentration and activity.

Turner, G. B.; Decker, S. R.; Tucker, M. P.; Law, C.; Doeppke, C.; Sykes, R. W.; Davis, M. F.; Ziebell, A.

2012-06-01T23:59:59.000Z

16

High-Throughput Thin Film Approach for Screening of Temperature-Pressure-Composition Phase Space  

SciTech Connect

Many solar energy technologies, for example CIGS and CdTe photovoltaics, utilize materials in thin film form. The equilibrium phase diagrams for these and other more novel solar energy materials are not known or are irrelevant because of the non-equilibrium character of the thin film growth processes. We demonstrate a high-throughput thin film approach for screening of temperature-pressure-composition phase diagrams and phase spaces. The examples in focus are novel solar absorbers Cu-N, Cu-O and p-type transparent conductors in the Cr2O3-MnO system. The composition axis of the Cr2O3-MnO phase diagram was screened using a composition spread method. The temperature axis of the Mn-O phase diagram was screened using a temperature spread method. The pressure axes of the Cu-N and Cu-O phase diagrams were screened using rate spread method with the aid of non-equilibrium growth phenomena. Overall these three methods constitute an approach to high-throughput screening of inorganic thin film phase diagrams. This research is supported by U.S. Department of Energy as a part of two NextGen Sunshot projects and an Energy Frontier Research Center.

Zakutayev, A.; Subramaniyan, A.; Caskey, C. M.; Ndione, P. F.; Richards, R. M.; O'Hayre, R.; Ginley, D. S.

2013-01-01T23:59:59.000Z

17

Methods and technologies for high-throughput and high-content small animal screening  

E-Print Network (OSTI)

High-throughput and high-content screening (HTS and HCS) of whole animals requires their immobilization for high-resolution imaging and manipulation. Here we present methods to enable HTS and HCS of the nematode Caenorhabditis ...

Rohde, Christopher, 1979-

2012-01-01T23:59:59.000Z

18

High throughput solar cell ablation system  

SciTech Connect

A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.

Harley, Gabriel; Pass, Thomas; Cousins, Peter John; Viatella, John

2012-09-11T23:59:59.000Z

19

Building a High Throughput Screening Facility in an Academic Setting  

E-Print Network (OSTI)

being developed in the biotechnology and pharmaceutical industries as means to speed the identification share some of the same goals as their counterparts in industry, their needs also differ in key ways. For example, most industry screening programs focus their efforts on a relatively small number of disease

Mitchison, Tim

20

High-Throughput Multiplex Screening of Biomolecule Samples ...  

A Berkeley Lab team of researchers led by Hoi-Ying Holman has invented a fast and elegant system for on-chip printing of picoliter-sized samples of plant cell-wall ...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

High-throughput screening assay of hepatitis C virus helicase inhibitors using fluorescence-quenching phenomenon  

Science Conference Proceedings (OSTI)

We have developed a novel high-throughput screening assay of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase inhibitors using the fluorescence-quenching phenomenon via photoinduced electron transfer between fluorescent dyes and guanine bases. We prepared double-stranded DNA (dsDNA) with a 5'-fluorescent-dye (BODIPY FL)-labeled strand hybridized with a complementary strand, the 3'-end of which has guanine bases. When dsDNA is unwound by helicase, the dye emits fluorescence owing to its release from the guanine bases. Our results demonstrate that this assay is suitable for quantitative assay of HCV NS3 helicase activity and useful for high-throughput screening for inhibitors. Furthermore, we applied this assay to the screening for NS3 helicase inhibitors from cell extracts of microorganisms, and found several cell extracts containing potential inhibitors.

Tani, Hidenori [Department of Life Science and Medical Bio-Science, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480 (Japan); Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 (Japan); Akimitsu, Nobuyoshi [Radioisotope Center, University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 (Japan); Fujita, Osamu; Matsuda, Yasuyoshi [Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 (Japan); Department of Life Science and Medical Bio-Science, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480 (Japan); Miyata, Ryo [Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 (Japan); Tsuneda, Satoshi [Department of Life Science and Medical Bio-Science, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480 (Japan); Igarashi, Masayuki [Microbial Chemistry Research Center, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan); Sekiguchi, Yuji [Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 (Japan); Noda, Naohiro [Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566 (Japan); Department of Life Science and Medical Bio-Science, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480 (Japan)], E-mail: noda-naohiro@aist.go.jp

2009-02-20T23:59:59.000Z

22

Design of a High-Throughput Plasma-Processing System  

DOE Green Energy (OSTI)

Sandia National Laboratories has demonstrated significant performance gains in crystalline silicon solar cell technology through the use of plasma-processing for the deposition of silicon nitride by Plasma Enhanced Chemical Vapor Deposition (PECVD), plasma-hydrogenation of the nitride layer, and reactive-ion etching of the silicon surface prior to the deposition to decrease the reflectivity of the surface. One of the major problems of implementing plasma processing into a cell production line is the batch configuration and/or low throughput of the systems currently available. This report describes the concept of a new in-line plasma processing system that could meet the industrial requirements for a high-throughput and cost effective solution for mass production of solar cells.

Darkazalli, Ghazi; Matthei, Keith; Ruby, Douglas S.

1999-07-20T23:59:59.000Z

23

High Throughput Screening for the Discovery of More Efficient Catalysts for Emissions Control  

DOE Green Energy (OSTI)

High-throughput synthesis and screening methods have been developed for the discovery of highly active catalysts for the control of emissions from stationary and mobile sources. Low temperature CO oxidation, CO methanation, NOx abatement and the destruction of Volatile Organic Compounds (VOCs) will be discussed. The discovery libraries for primary screening consisted of both 11x11 and 16x16 catalyst arrays on 3 inch and 4 inch quartz wafers, respectively. Catalysts were prepared by robotic liquid dispensing techniques and screened for catalytic activity in Symyx's Scanning Mass Spectrometer. The screening protocols encompassed mixed metal oxides, perovskites and supported base and noble metals. Active hits were further optimized in focus libraries using shallower compositional gradients. The ScanMS is a fast serial screening tool that uses flat wafer catalyst surfaces, local laser heating, a scanning/sniffing nozzle and a quadrupolar mass spectrometer to compare relative catalytic activities. The temperature range from 200C to 600C is accessible. Typically, 256 catalysts can be screened per day and about 100,000 experiments conducted annually.

Yaccato, Karin; Hagemeyer, Alfred; Volpe, Anthony; Weinberg, Henry

2004-03-31T23:59:59.000Z

24

The Materials genome : rapid materials screening for renewable energy using high-throughput density functional theory  

E-Print Network (OSTI)

This thesis relates to the emerging field of high-throughput density functional theory (DFT) computation for materials design and optimization. Although highthroughput DFT is a promising new method for materials discovery, ...

Jain, Anubhav, Ph.D. Massachusetts Institute of Technology

2011-01-01T23:59:59.000Z

25

Baculovirus expression system and method for high throughput expression of genetic material  

DOE Patents (OSTI)

The present invention provides novel recombinant baculovirus expression systems for expressing foreign genetic material in a host cell. Such expression systems are readily adapted to an automated method for expression foreign genetic material in a high throughput manner. In other aspects, the present invention features a novel automated method for determining the function of foreign genetic material by transfecting the same into a host by way of the recombinant baculovirus expression systems according to the present invention.

Clark, Robin (Benecia, CA); Davies, Anthony (Mill Valley, CA)

2001-01-01T23:59:59.000Z

26

Abstract--Design aspects of a minimally invasive high-throughput automation system for radiation biodosimetry are  

E-Print Network (OSTI)

for radiation exposure. Only those showing both internal and external contamination were examined usingAbstract--Design aspects of a minimally invasive high- throughput automation system for radiation was supported by grant number U19 AI067773, the Center for High-Throughput Minimally Invasive Radiation

27

DotDFS: A Grid-based high-throughput file transfer system  

Science Conference Proceedings (OSTI)

DotGrid platform is a Grid infrastructure integrated with a set of open and standard protocols recently implemented on the top of Microsoft .NET in Windows and MONO .NET in UNIX/Linux. DotGrid infrastructure along with its proposed protocols provides ... Keywords: Concurrent systems, Data grids, Event-driven architecture, File transfer protocols, Grid computing, Grid security, High throughput file transfer, Modeling parallel TCP throughput

Alireza Poshtkohi; M. B. Ghaznavi-Ghoushchi

2011-02-01T23:59:59.000Z

28

The Development of Microfabricated Microbial Fuel Cell Array as a High Throughput Screening Platform for Electrochemically Active Microbes  

E-Print Network (OSTI)

Microbial fuel cells (MFCs) are novel green technologies that convert chemical energy stored in biomass into electricity through microbial metabolisms. Both fossil fuel depletion and environmental concern have fostered significant interest in MFCs for both wastewater treatment and electricity generation. However, MFCs have not yet been used for practical applications due to their low power outputs and challenges associated with scale-up. High throughput screening devices for parallel studies are highly necessary to significantly improve and optimize MFC working conditions for future practical applications. Here in this research, microfabricated platforms of microbial fuel cell array as high throughput screening devices for MFC parallel studies have been developed. Their utilities were described with environmental sample screening to uncover electricigens with higher electrochemical activities. The first version of the MFC arrays is a batch-mode miniaturized 24-well MFC array using ferricyanide as catholyte. Several environmental species that showed higher electricity generation capabilities than Shewanella oneidensis MR-1 (SO) were uncovered using the developed MFC array, with one environmental electricigen, Shewanella sp. Hac353 (dq307734.1)(7Ca), showing 2.3-fold higher power output than SO. The second MFC array platform developed is an air-cathode MFC array using oxygen in air as electron acceptor, which is sustainable compared to ferricyanide that depletes over time. Environmental electricigen screenings were also conducted, showing parallel comparison capabilities of the developed array. The third MFC array platform is a microfluidic-cathode MFC array that enables long-term operations of miniature MFC arrays with improved power generation abilities. The capability of the microfluidic-cathode MFC array to support long-term parallel analysis was demonstrated by characterizing power generation of SO and 7Ca, proving extended operation time and improved power outputs compared to batch-mode MFC array. The fourth MFC array platform enables both catholyte and anolyte replenishments for long-term characterization of various carbon substrate performances. Finally, the 24-well microfluidic MFC array was further scaled up to 96 wells, which greatly increased the throughput of MFC parallel studies. The developed MFC arrays as high throughput screening platforms are expected to greatly impact how current MFC studies are conducted and ultimately lead to significant improvement in MFC power output.

Hou, Huijie

2011-12-01T23:59:59.000Z

29

High Throughput Combinatorial Screening of Biometic Metal-Organic Materials for Military Hydrogen-Storage Materials (New Joint Miami U/NREL DoD/DLA Project) (presentation)  

NLE Websites -- All DOE Office Websites (Extended Search)

Miami University/NREL DoD/DLA Project Miami University/NREL DoD/DLA Project High throughput combinatorial screening of biomimetic metal-organic materials for military hydrogen-storage applications Philip Parilla - NREL Joe Zhou, Dan Zhao - Miami U, Ohio Jeff Blackburn, Kevin O'Neill, Lin Simpson, Mike Heben - NREL Outline * Miami/NREL Project - Synthesis (Miami) - High Throughput Characterization (NREL) - Other Characterization * Other High Throughput Activities (NREL) - Parallel Sieverts - Parallel Gravimetric * Final Comments Overview of Miami/NREL Project * Goals - Development of H 2 storage materials based on MOFs, targeting 15 kJ/mole binding energy and high density of H 2 sites - Development of optical-based detection of adsorbed H 2 allowing rapid screening of samples * Approach - Combinatorial MOFs synthesis involving 8

30

Lobanov & Agrafiotis 1 Combinatorial Chemistry & High-Throughput Screening., in press  

E-Print Network (OSTI)

(Typical) #12;8 User Manual Advanced Lighting Systems The Frick Chemistry Lab was planned, designed lights in un- occupied areas. Also, using the daylight sensor, the system will read the amount of light 8 Environmental and Other Systems 12 Working Spaces Environmental Health and Safety Information 20

Agrafiotis, Dimitris K.

31

Lignocellulose Recalcitrance Screening by Integrated High Throughput Hydrothermal Pretreatment and Enzymatic Saccharification  

SciTech Connect

We report a novel 96-well multiplate reactor system for comparative analysis of lignocellulose recalcitrance via integrated hydrothermal pretreatment and enzymatic saccharification. The system utilizes stackable nickel/gold-plated 96-well aluminum reactor plates, a clamping device fit to a standard Parr reactor, and robotics for efficient liquids and solids handling. A capacity of 20 plates allows up to 1,920 separate hydrothermal reactions per run. Direct and rapid analysis of key end-products, glucose and xylose, is facilitated by the use of glucose oxidase/peroxidase and xylose dehydrogenase-linked assays. To demonstrate efficacy, a set of 755 poplar core samples from the US Department of Energy's BioEnergy Science Center was tested. Total sugar release ranged from 0.17 to 0.64 g/g of biomass and correlated strongly with the ratio of syringyl to guaiacyl lignins in the samples. Variance among sample replicates was sufficiently minimal to permit clear assignment of differences in recalcitrance throughout this large sample set.

Selig, M. J.; Tucker, M. P.; Sykes, R. W.; Reichel, K. L.; Brunecky, R.; Himmel, M. E.; Davis, M. F.; Decker, S. R.

2010-04-01T23:59:59.000Z

32

Automated high-throughput flow-through real-time diagnostic system  

DOE Patents (OSTI)

An automated real-time flow-through system capable of processing multiple samples in an asynchronous, simultaneous, and parallel fashion for nucleic acid extraction and purification, followed by assay assembly, genetic amplification, multiplex detection, analysis, and decontamination. The system is able to hold and access an unlimited number of fluorescent reagents that may be used to screen samples for the presence of specific sequences. The apparatus works by associating extracted and purified sample with a series of reagent plugs that have been formed in a flow channel and delivered to a flow-through real-time amplification detector that has a multiplicity of optical windows, to which the sample-reagent plugs are placed in an operative position. The diagnostic apparatus includes sample multi-position valves, a master sample multi-position valve, a master reagent multi-position valve, reagent multi-position valves, and an optical amplification/detection system.

Regan, John Frederick

2012-10-30T23:59:59.000Z

33

Application of high throughput pretreatment and cohydrolysis...  

NLE Websites -- All DOE Office Websites (Extended Search)

1 Biofuels and Environmental Biotechnology Biotechnology and Bioengineering DOI 10.1002bit.24951 Application of High Throughput Pretreatment and Co-Hydrolysis System to...

34

A High-Throughput 3-D X-ray Microtomography System with Real-Time 3-D  

NLE Websites -- All DOE Office Websites (Extended Search)

Throughput 3-D X-ray Microtomography System with Real-Time 3-D Throughput 3-D X-ray Microtomography System with Real-Time 3-D Reconstruction A high-throughput x-ray microtomography system (XMS) that can acquire, reconstruct, and interactively display rendered 3-D images of a sample at micrometer-scale resolution within minutes has been developed at Advanced Photon Source (APS) beamline 2-BM, which is managed by the Synchrotron Radiation Instrumentation Collaborative Access Team (SRI-CAT). This system could bring better understanding of an array of scientific and technological problems, ranging from failure in microelectronic devices to structures in biological samples. A rendered image from a three-dimensional tomographic reconstruction of a cricket, obtained with the x-ray microtomography system. The image has been digitally cut at different planes to show the internal structures of the cricket's head.

35

Design and fabrication of a microfluidies gradient generator system for high-throughput molecular interaction studies  

E-Print Network (OSTI)

Design and fabrication of a microfluidics system capable of generating reproducible and controlled micro-biochemical environments that can be used as a diagnostic assay and microreactor is important. Here, a simple technique ...

Chen, Guan-Jong, 1981-

2004-01-01T23:59:59.000Z

36

High throughput optical scanner  

SciTech Connect

A scanning apparatus is provided to obtain automated, rapid and sensitive scanning of substrate fluorescence, optical density or phosphorescence. The scanner uses a constant path length optical train, which enables the combination of a moving beam for high speed scanning with phase-sensitive detection for noise reduction, comprising a light source, a scanning mirror to receive light from the light source and sweep it across a steering mirror, a steering mirror to receive light from the scanning mirror and reflect it to the substrate, whereby it is swept across the substrate along a scan arc, and a photodetector to receive emitted or scattered light from the substrate, wherein the optical path length from the light source to the photodetector is substantially constant throughout the sweep across the substrate. The optical train can further include a waveguide or mirror to collect emitted or scattered light from the substrate and direct it to the photodetector. For phase-sensitive detection the light source is intensity modulated and the detector is connected to phase-sensitive detection electronics. A scanner using a substrate translator is also provided. For two dimensional imaging the substrate is translated in one dimension while the scanning mirror scans the beam in a second dimension. For a high throughput scanner, stacks of substrates are loaded onto a conveyor belt from a tray feeder.

Basiji, David A. (Seattle, WA); van den Engh, Gerrit J. (Seattle, WA)

2001-01-01T23:59:59.000Z

37

Data Management for High-Throughput Genomics  

E-Print Network (OSTI)

Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be automatically processed and made available to scientists for further analysis. This paper explores the potential and the limitations of using relational database systems as the data processing platform for high-throughput genomics. In particular, we are interested in the storage management for high-throughput sequence data and in leveraging SQL and user-defined functions for data analysis inside a database system. We give an overview of a database design for high-throughput genomics, how we used a SQL Server database in some unconventional ways to prototype this scenario, and we will discuss some initial findings about the scalability and performance of such a more database-centric approach.

Roehm, Uwe

2009-01-01T23:59:59.000Z

38

Review: Clustering of high throughput gene expression data  

Science Conference Proceedings (OSTI)

High throughput biological data need to be processed, analyzed, and interpreted to address problems in life sciences. Bioinformatics, computational biology, and systems biology deal with biological problems using computational methods. Clustering is ... Keywords: Bioinformatics, Clustering, Gene expression data, High throughput data, Microarrays

Harun Pirim; Burak Ek?Io?Lu; Andy D. Perkins; Etin YCeer

2012-12-01T23:59:59.000Z

39

High throughput 3-D tissue cytometry  

E-Print Network (OSTI)

This thesis presents the ongoing technological development of high throughput 3-D tissue cytometry.and its applications in biomedicine. 3-D tissue cytometry has been developed in our laboratory based on two-photon microscopy ...

Kwon, Hyuk-Sang, 1971-

2007-01-01T23:59:59.000Z

40

Area-efficient high-throughput MAP decoder architectures  

Science Conference Proceedings (OSTI)

Iterative decoders such as turbo decoders have become integral components of modern broadband communication systems because of their ability to provide substantial coding gains. A key computational kernel in iterative decoders is the maximum a posteriori ... Keywords: area efficient, block-interleaved pipelining, high throughput, parallel processing, pipeline, symbol-based decoding, turbo decoder, turbo equalizer

Seok-Jun Lee; Naresh R. Shanbhag; Andrew C. Singer

2005-08-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Co-hydrolysis of hydrothermal and dilute acid pretreated Populus slurries to support development of a high-throughput pretreatment system  

E-Print Network (OSTI)

system. Biotechnology for Biofuels 2011 Submit your nextStuder et al. Biotechnology for Biofuels 2011, 4:19 http://Studer et al. Biotechnology for Biofuels 2011, 4:19 http://

Studer, Michael H; Brethauer, Simone; DeMartini, Jaclyn D; McKenzie, Heather L; Wyman, Charles E

2011-01-01T23:59:59.000Z

42

High-Throughput Approaches to Optimization of Crystal ...  

high-throughput approaches to optimization of crystal silicon surface passivation and heterojunction solar cells qi wanga, matt page, yanfa yan, and ...

43

Potential of High-Throughput Experimentation with Ammonia Borane...  

NLE Websites -- All DOE Office Websites (Extended Search)

of High-Throughput Experimentation with Ammonia Borane Solid Hydrogen Storage Materials Jonathan L. Male Pacific Northwest National Laboratory June 26, 2006 US Department of Energy...

44

Novel System for Recalcitrance Screening Will Reduce Biofuels Production Costs; The Spectrum of Clean Energy Innovation (Fact Sheet)  

SciTech Connect

Fact sheet describes a high-throughput screening process, developed at NREL, that enables researchers to screen a large variety of biomass feedstocks for traits that indicate they would easily convert to fermentable sugars.

Not Available

2010-06-01T23:59:59.000Z

45

Applications of High-Throughput Screening Tools for Thermoelectric ...  

Science Conference Proceedings (OSTI)

Author(s), Winnie Wong-Ng, Makoto Otani, Joshua Martin, Evans L Thomas, Yonggao Yan, Martin L Green. On-Site Speaker (Planned), Winnie Wong-Ng.

46

High Throughput/Combinatorial Screening of Hydrogen Storage Materials...  

NLE Websites -- All DOE Office Websites (Extended Search)

DOE targets * Synthesis Methodology - Need: discrete, scalable sample preparation Ball milling predominant in literature Solvent approach of interest * Characterization Methodology...

47

High-Throughput and Combinatorial Screening of Hydrogen Storage...  

NLE Websites -- All DOE Office Websites (Extended Search)

for New Complex Metal Hydrides Established a synthesis route that combines high-energy milling (SPEX) followed by hot-sintering under high H 2 -pressures (in-house station) Normal...

48

High-Throughput/Combinatorial Techniques in Hydrogen Storage...  

NLE Websites -- All DOE Office Websites (Extended Search)

High-ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D Ned Stetson, Larry Blair 1 , Grace Ordaz, Carole Read, George Thomas 2 , and Sunita Satyapal Suite 900,...

49

Fuel Cell Technologies Office: High-Throughput/Combinatorial...  

NLE Websites -- All DOE Office Websites (Extended Search)

High-ThroughputCombinatorial Techniques in Hydrogen Storage Materials R&D On June 26, 2007 the Hydrogen Storage Program of the U.S. Department of Energy (DOE) held a one-day...

50

High Throughput, Continuous, Mass Production of Photovoltaic Modules  

DOE Green Energy (OSTI)

AVA Solar has developed a very low cost solar photovoltaic (PV) manufacturing process and has demonstrated the significant economic and commercial potential of this technology. This I & I Category 3 project provided significant assistance toward accomplishing these milestones. The original goals of this project were to design, construct and test a production prototype system, fabricate PV modules and test the module performance. The original module manufacturing costs in the proposal were estimated at $2/Watt. The objectives of this project have been exceeded. An advanced processing line was designed, fabricated and installed. Using this automated, high throughput system, high efficiency devices and fully encapsulated modules were manufactured. AVA Solar has obtained 2 rounds of private equity funding, expand to 50 people and initiated the development of a large scale factory for 100+ megawatts of annual production. Modules will be manufactured at an industry leading cost which will enable AVA Solar's modules to produce power that is cost-competitive with traditional energy resources. With low manufacturing costs and the ability to scale manufacturing, AVA Solar has been contacted by some of the largest customers in the PV industry to negotiate long-term supply contracts. The current market for PV has continued to grow at 40%+ per year for nearly a decade and is projected to reach $40-$60 Billion by 2012. Currently, a crystalline silicon raw material supply shortage is limiting growth and raising costs. Our process does not use silicon, eliminating these limitations.

Kurt Barth

2008-02-06T23:59:59.000Z

51

Robust, High-Throughput Analysis of Protein Structures  

NLE Websites -- All DOE Office Websites (Extended Search)

Robust, High-Throughput Analysis of Protein Structures Print Robust, High-Throughput Analysis of Protein Structures Print Scientists have developed a fast and efficient way to determine the structure of proteins, shortening a process that often takes years into a matter of days. The Structurally Integrated BiologY for Life Sciences (SIBYLS) beamline at the ALS has implemented the world's highest-throughput biological-solution x-ray scattering beamline enabling genomic-scale protein-structure characterization. Coupling brilliant x rays from one of the superconducting bend magnets at the ALS to liquid-handling robotics has enabled the collection of 96 samples in 4 hours. Importantly, the sample format and the amount of material required are practical for most biological problems. The beamline's high-throughput capability is set to have a large impact on many fields that require genomic-scale information, such as Berkeley Lab's bioenergy efforts and cancer biology studies.

52

Unstructured Data Analysis of Streaming Video Using Parallel, High-Throughput Algorithms  

Science Conference Proceedings (OSTI)

This paper describes the methods, algorithms, and implementation of high-throughput video processing.

Trease, Harold E.; Carlson, Timothy S.; Moony, Ryan; Farber, Robert M.; Trease, Lynn L.

2007-12-31T23:59:59.000Z

53

High throughput liquid absorption preconcentrator sampling instrument  

DOE Patents (OSTI)

A system for detecting trace concentrations of an analyte in air includes a preconcentrator for the analyte and an analyte detector. The preconcentrator includes an elongated tubular container comprising a wettable material. The wettable material is continuously wetted with an analyte-sorbing liquid which flows from one part of the container to a lower end. Sampled air flows through the container in contact with the wetted material with a swirling motion which results in efficient transfer of analyte vapors or aerosol particles to the sorbing liquid and preconcentration of traces of analyte in the liquid. The preconcentrated traces of analyte may be either detected within the container or removed therefrom for injection into a separate detection means or for subsequent analysis. 12 figs.

Zaromb, S.; Bozen, R.M.

1990-03-26T23:59:59.000Z

54

A GPU-based high-throughput image retrieval algorithm  

Science Conference Proceedings (OSTI)

With the development of Internet and cloud computing, multimedia data, such as images and videos, has become one of the most common data types being processed. As the scale of multimedia data being still increasing, it is vitally important to efficiently ... Keywords: GPU-based, SURF, high throughput, image retrieval

Feiwen Zhu; Peng Chen; Donglei Yang; Weihua Zhang; Haibo Chen; Binyu Zang

2012-03-01T23:59:59.000Z

55

Scaling up transit priority modelling using high-throughput computing  

Science Conference Proceedings (OSTI)

The optimization of Road Space Allocation (RSA) from a network perspective is computationally challenging. An analogue to the Network Design Problem (NDP), RSA can be classified NP-hard. In large-scale networks when the number of alternatives increases ... Keywords: genetic algorithm, high-performance computing, high-throughput computing, transport modelling

Mahmoud Mesbah, Majid Sarvi, Jefferson Tan, Fateme Karimirad

2012-01-01T23:59:59.000Z

56

High throughput lessons from the LHC experience.Johnston.TNC2013  

NLE Websites -- All DOE Office Websites (Extended Search)

high throughput in widely distributed data high throughput in widely distributed data management and analysis systems: Lessons from the LHC William E. Johnston ESnet, Lawrence Berkeley National Laboratory e-mail: wej@es.net Eli Dart ESnet, Lawrence Berkeley National Laboratory e-mail: dart@es.net Michael Ernst RHIC and ATLAS Computing Facility, Brookhaven National Laboratory e-mail: mernst@bnl.gov Brian Tierney ESnet, Lawrence Berkeley National Laboratory e-mail: bltierney@es.net Paper type Technical paper Abstract Today's large-scale science projects all involve world-wide collaborations that must routinely move 10s of petabytes per year between international sites in order to be successful. This is true for the two largest experiments at the Large Hadron Collider (LHC) at CERN - ATLAS and CMS - and for the climate science

57

High-Throughput Transfer Imprinting for Organic Semiconductors  

E-Print Network (OSTI)

Development of nanoimprint lithography(NIL) has enabled high-throughput and high-resolution patterning over the optical limitation. In recent years, thermal nanoimprint has been used to directly pattern functional materials such as organic semiconductors because heat and pressure used in thermal nanoimprint do not damage functional materials. However, issues such as residual layer removal and mold contamination still limit the application of nanoimprint for organic semiconductor patterning. In this work, nanoimprint-based transfer imprinting of organic semiconductor is studied. In the same time the suggested technique is simulated with COMSOL multi-physics simulator to understand its mechanism. This transfer printing technique utilize thermal nanoimprint scheme to enable residual-layer-free patterning of organic semiconductors without mold contamination. The transfer imprinting technique is amenable to roll-to-roll process for high-throughput patterning of organic semiconductors for low-cost organic electronic applications.

Choo, Gihoon

2013-08-01T23:59:59.000Z

58

Hypercontraction and Drosophila : a model system for the study of human myopathies  

E-Print Network (OSTI)

Currently, there are no therapeutic interventions which fully alleviate the defects associated with muscular dystrophies and cardiomyopathies. Development of model systems in which to utilize high-throughput screens for ...

Montana, Enrico Sakai

2005-01-01T23:59:59.000Z

59

NIST Study Finds a Decade of High-Payoff, High-Throughput ...  

Science Conference Proceedings (OSTI)

NIST Study Finds a Decade of High-Payoff, High-Throughput Research. For Immediate Release: May 20, 2009. ...

2013-06-12T23:59:59.000Z

60

Updating Interconnection Screens for PV System Integration  

DOE Green Energy (OSTI)

This white paper evaluates the origins and usefulness of the capacity penetration screen, offer short-term solutions which could effectively allow fast-track interconnection to many PV system applications, and considers longer-term solutions for increasing PV deployment levels in a safe and reliable manner while reducing or eliminating the emphasis on the penetration screen. Short-term and longer-term alternatives approaches are offered as examples; however, specific modifications to screening procedures should be discussed with stakeholders and must ultimately be adopted by state and federal regulatory bodies.

Coddington, M.; Mather, B.; Kroposki, B.; Lynn, K.; Razon, A.; Ellis, A.; Hill, R.; Key, T.; Nicole, K.; Smith, J.

2012-02-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

HIGH-THROUGHPUT/COMBINATORIAL TECHNIQUES IN HYDROGEN STORAGE MATERIALS R&D WORKSHOP  

E-Print Network (OSTI)

HIGH-THROUGHPUT/COMBINATORIAL TECHNIQUES IN HYDROGEN STORAGE MATERIALS R&D WORKSHOP U.S. Department of Energy Office of Hydrogen, Fuel Cells and Infrastructure Technologies June 26, 2007 Bethesda, MD On June 26, 2007, DOE's Hydrogen Storage Program held a one-day High- Throughput/Combinatorial Techniques

62

Anaerobic High-Throughput Cultivation Method for Isolation of Thermophiles Using Biomass-Derived Substrates  

Science Conference Proceedings (OSTI)

Flow cytometry (FCM) techniques have been developed for sorting mesophilic organisms, but the difficulty increases if the target microbes are thermophilic anaerobes. We demonstrate a reliable, high-throughput method of screening thermophilic anaerobic organisms using FCM and 96-well plates for growth on biomass-relevant substrates. The method was tested using the cellulolytic thermophiles Clostridium ther- mocellum (Topt = 55 C), Caldicellulosiruptor obsidiansis (Topt = 78 C) and the fermentative hyperthermo- philes, Pyrococcus furiosus (Topt = 100 C) and Thermotoga maritima (Topt = 80 C). Multi-well plates were incubated at various temperatures for approximately 72 120 h and then tested for growth. Positive growth resulting from single cells sorted into individual wells containing an anaerobic medium was verified by OD600. Depending on the growth substrate, up to 80 % of the wells contained viable cultures, which could be transferred to fresh media. This method was used to isolate thermophilic microbes from Rabbit Creek, Yellowstone National Park (YNP), Wyoming. Substrates for enrichment cultures including crystalline cellulose (Avicel), xylan (from Birchwood), pretreated switchgrass and Populus were used to cultivate organisms that may be of interest to lignocellulosic biofuel production.

Hamilton-Brehm, Scott [ORNL; Vishnivetskaya, Tatiana A [ORNL; Allman, Steve L [ORNL; Mielenz, Jonathan R [ORNL; Elkins, James G [ORNL

2012-01-01T23:59:59.000Z

63

Metal Organic Framework Research: High Throughput Discovery of Robust Metal Organic Framework for CO2 Capture  

Science Conference Proceedings (OSTI)

IMPACCT Project: LBNL is developing a method for identifying the best metal organic frameworks for use in capturing CO2 from the flue gas of coal-fired power plants. Metal organic frameworks are porous, crystalline compounds that, based on their chemical structure, vary considerably in terms of their capacity to grab hold of passing CO2 molecules and their ability to withstand the harsh conditions found in the gas exhaust of coal-fired power plants. Owing primarily to their high tunability, metal organic frameworks can have an incredibly wide range of different chemical and physical properties, so identifying the best to use for CO2 capture and storage can be a difficult task. LBNL uses high-throughput instrumentation to analyze nearly 100 materials at a time, screening them for the characteristics that optimize their ability to selectively adsorb CO2 from coal exhaust. Their work will identify the most promising frameworks and accelerate their large-scale commercial development to benefit further research into reducing the cost of CO2 capture and storage.

None

2010-08-01T23:59:59.000Z

64

Cell bioprinting as a potential high-throughput method for fabricating cell-based biosensors (CBBs)  

E-Print Network (OSTI)

Cell-based biosensors (CBBs) are becoming an important tool for biosecurity applications and rapid diagnostics. For current CBBs technology, cell immobilization and high throughput fabrication are the main challenges. To ...

Xu, F.

65

An instrument for high-throughput measurements of fiber mechanical properties  

E-Print Network (OSTI)

In this thesis, an instrument is designed and constructed for the purpose of measuring the mechanical properties of single fibers. The instrument is intended to provide high throughput measurement of single fiber geometric ...

Kristofek, Grant William, 1980-

2005-01-01T23:59:59.000Z

66

Screen payback on cogeneration-system options  

SciTech Connect

Presented here are charts that provide a quick look at the relationship among the primary variables that affect the viability of a cogeneration project. The graphs are not intended to be complete feasibility studies, but rather screening aids for understanding the important interrelationships. Use of the charts will enable engineers to compare the predominant system options: gas turbine with heat-recovery steam generator (HRSG), diesel engine with HRSG, and fired boiler with steam turbine. The three options are presented separately because of differing capital costs and heat balances.

Wilson, F.

1984-06-01T23:59:59.000Z

67

Miniaturized Analytical Platforms From Nanoparticle Components: Studies in the Construction, Characterization, and High-Throughput Usage of These Novel Architectures  

Science Conference Proceedings (OSTI)

The scientific community has recently experienced an overall effort to reduce the physical size of many experimental components to the nanometer size range. This size is unique as the characteristics of this regime involve aspects of pure physics, biology, and chemistry. One extensively studied example of a nanometer sized experimental component, which acts as a junction between these three principle scientific theologies, is deoxyribonucleic acid (DNA) or ribonucleic acid (RNA). These biopolymers not only contain the biological genetic guide to code for the production of life-sustaining materials, but are also being probed by physicists as a means to create electrical circuits and furthermore as controllable architectural and sensor motifs in the chemical disciplines. Possibly the most common nano-sized component between these sciences are nanoparticles composed of a variety of materials. The cross discipline employment of nanoparticles is evident from the vast amount of literature that has been produced from each of the individual communities within the last decade. Along these cross-discipline lines, this dissertation examines the use of several different types of nanoparticles with a wide array of surface chemistries to understand their adsorption properties and to construct unique miniaturized analytical and immunoassay platforms. This introduction will act as a literature review to provide key information regarding the synthesis and surface chemistries of several types of nanoparticles. This material will set the stage for a discussion of assembling ordered arrays of nanoparticles into functional platforms, architectures, and sensors. The introduction will also include a short explanation of the atomic force microscope that is used throughout the thesis to characterize the nanoparticle-based structures. Following the Introduction, four research chapters are presented as separate manuscripts. Chapter 1 examines the self-assembly of polymeric nanoparticles exhibiting a variety of surface chemistries and attempts to deconvolute general adsorption rules for their assembly on various substrates. Chapter 2 extends the usage of self-assembly of polymeric nanoparticles through a layer-by-layer deposition concept and photolithography methodologies to create analytical platforms with a vertical height controlled within the nanometer regime. This platform is then furthered in Chapter 3 by employing this integrated concept as a bio-recognition platform, with the extension of the method to a high-throughput screening system explored. Chapter 4 exploits two different types of nanoparticles, silica and gold, as multiplexed, self-assembled immunoassay sensors. This final research chapter is followed by a general summation and future prospectus section that concludes the dissertation.

Andrew David Pris

2003-08-05T23:59:59.000Z

68

A search model for topological insulators with high-throughput robustness descriptors  

Science Conference Proceedings (OSTI)

Topological insulators (TI) are becoming one of the most studied classes of novel materials because of their great potential for applications ranging from spintronics to quantum computers. To fully integrate TI materials in electronic devices, high-quality epitaxial single-crystalline phases with sufficiently large bulk bandgaps are necessary. Current efforts have relied mostly on costly and time-consuming trial-and-error procedures. Here we show that by defining a reliable and accessible descriptor {cflx X}TI, which represents the topological robustness or feasibility of the candidate, and by searching the quantum materials repository aflowlib.org, we have automatically discovered 28 TIs (some of them already known) in five different symmetry families. These include peculiar ternary halides, Cs{l_brace}Sn,Pb,Ge{r_brace}{l_brace}Cl,Br,I{r_brace}{sub 3}, which could have been hardly anticipated without high-throughput means. Our search model, by relying on the significance of repositories in materials development, opens new avenues for the discovery of more TIs in different and unexplored classes of systems.

Yang, Kesong; Setyawan, Wahyu; Wang, Shidong; Nardelli, Marco B.; Curtarolo, Stephano

2012-05-13T23:59:59.000Z

69

Generalized Schemes for High Throughput Manipulation of the Desulfovibrio vulgaris Hildenborough Genome.  

Science Conference Proceedings (OSTI)

The ability to conduct advanced functional genomic studies of the thousands of 38 sequenced bacteria has been hampered by the lack of available tools for making high39 throughput chromosomal manipulations in a systematic manner that can be applied across 40 diverse species. In this work, we highlight the use of synthetic biological tools to 41 assemble custom suicide vectors with reusable and interchangeable DNA parts to 42 facilitate chromosomal modification at designated loci. These constructs enable an array 43 of downstream applications including gene replacement and creation of gene fusions with 44 affinity purification or localization tags. We employed this approach to engineer 45 chromosomal modifications in a bacterium that has previously proven difficult to 46 manipulate genetically, Desulfovibrio vulgaris Hildenborough, to generate a library of 47 662 strains. Furthermore, we demonstrate how these modifications can be used for 48 examining metabolic pathways, protein-protein interactions, and protein localization. The 49 ubiquity of suicide constructs in gene replacement throughout biology suggests that this 50 approach can be applied to engineer a broad range of species for a diverse array of 51 systems biological applications and is amenable to high-throughput implementation.

Chhabra, Swapnil [Lawrence Berkeley National Laboratory (LBNL); Butland, Gareth [Lawrence Berkeley National Laboratory (LBNL); Elias, Dwayne A [ORNL; Chandonia, John-Marc [Lawrence Berkeley National Laboratory (LBNL); Fok, Olivia [Lawrence Berkeley National Laboratory (LBNL); Juba, tom [University of Missouri; Gorur, A. [Lawrence Berkeley National Laboratory (LBNL); Allen, S. [University of California, San Francisco; Leung, C. M. [Lawrence Berkeley National Laboratory (LBNL); Keller, Kim [University of Missouri; Reveco, S. [Lawrence Berkeley National Laboratory (LBNL); Zane, Mr. Grant M. [University of Missouri, Columbia; Semkiw, Elizabeth M. [University of Missouri; Prathapam, R. [Lawrence Berkeley National Laboratory (LBNL); Gold, B. [Lawrence Berkeley National Laboratory (LBNL); Singer, Mary [Lawrence Berkeley National Laboratory (LBNL); Ouellet, M. [Lawrence Berkeley National Laboratory (LBNL); Sazakal, E. D. [University of California, San Francisco; Jorgens, Dominique [Lawrence Berkeley National Laboratory (LBNL); Price, Morgan N. [Lawrence Berkeley National Laboratory (LBNL); Witkowska, Ewa [University of California, San Francisco; Beller, Harry R. [Lawrence Berkeley National Laboratory (LBNL); Hazen, Terry [Lawrence Berkeley National Laboratory (LBNL); Biggin, Mark D. [Lawrence Berkeley National Laboratory (LBNL); Auer, Dr. Manfred [Lawrence Berkeley National Laboratory (LBNL); Wall, Judy D. [University of Missouri; Keasling, Jay [Lawrence Berkeley National Laboratory (LBNL)

2011-01-01T23:59:59.000Z

70

Synthesis and characterization of four new metal 5-phosphonoisophthalates discovered by high-throughput experimentation  

SciTech Connect

A new ligand, 5-diethylphosphonoisophthalic acid ((HOOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3}(C{sub 2}H{sub 5}){sub 2}, H{sub 2}Et{sub 2}L), for the hydrothermal synthesis of inorganic-organic hybrid compounds was prepared and characterized by NMR-spectroscopy. Its in situ hydrolysis leads to the corresponding 5-phosphonoisophthalic acid ((HOOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3}H{sub 2}, H{sub 4}L). Applying high-throughput methods, different di- and trivalent metal salts for the synthesis of crystalline metal phosphonates based on H{sub 2}Et{sub 2}L have been screened. From the resulting discovery library, single-crystals of four new compounds, [Sm{sub 2}(H{sub 2}O){sub 4}(H(OOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3}){sub 2}].2H{sub 2}O (1), [Cu{sub 3}(H{sub 2}O)(H(OOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3}){sub 2}].2H{sub 2}O (2), Ca{sub 2}(H{sub 2}O)[H(OOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3}H]{sub 2} (3), and Ba{sub 2}(H{sub 2}O){sub 3}(OOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3} (4), have been isolated. The single-crystal structure determination of the title compounds shows H{sub 4}L to be a versatile ligand, exhibiting different types of coordination modes between the functional groups and the metal ions. A comparison of the structural features of the title compounds shows a varying degree of M-O-M connectivities. Thus, isolated metal-oxygen clusters (compounds 1 and 2), infinite M-O-M chains (compound 3), and infinite M-O-M layers (compound 4) are observed. The title compounds 1, 2, and 3 were further characterized by IR-spectroscopy, TG-, EDX-, and elemental chemical analysis. - Graphical abstract: Applying high-throughput methods, the new ligand 5-diethylphosphonoisophtalic acid, (HOOC){sub 2}C{sub 6}H{sub 3}-PO{sub 3}(C{sub 2}H{sub 5}){sub 2} (H{sub 2}Et{sub 2}L), was reacted with several di- and trivalent metal salts under hydrothermal conditions. Single-crystals of four new inorganic-organic hybrid compounds were isolated from the discovery library. The single-crystal structure analysis shows a varying M-O-M connectivity.

Bauer, Sebastian [Institute of Inorganic Chemistry, Christian-Albrechts-University, Otto-Hahn-Platz 6/7, D 24098 Kiel (Germany); Stock, Norbert [Institute of Inorganic Chemistry, Christian-Albrechts-University, Otto-Hahn-Platz 6/7, D 24098 Kiel (Germany)], E-mail: stock@ac.uni-kiel.de

2007-11-15T23:59:59.000Z

71

High-Throughput identification of chemistry in life science texts  

Science Conference Proceedings (OSTI)

OSCAR3 is an open extensible system for the automated annotation of chemistry in scientific articles, which can process thousands of articles per hour. This XML annotation supports applications such as interactive browsing and chemically-aware searching, ...

Peter Corbett; Peter Murray-Rust

2006-09-01T23:59:59.000Z

72

High throughput screen for cells with high extracellular metabolite consumption--secretion rates using microfluidic droplets  

E-Print Network (OSTI)

Metabolic engineering has contributed significantly to the improvement of strains for the industrial production of various compounds. Traditionally, enzymatic steps closely associated with the product-forming pathway have ...

Wang, Benjamin L. (Benjamin Lu chen)

2009-01-01T23:59:59.000Z

73

A High-throughput Screening Approach Identifies Selective Regulators of Il12b Transcription  

E-Print Network (OSTI)

TLR4, in contrast to NF-kB and AP-1, whose activities aresignaling pathways, such as NF-kB and MAP kinase pathways,

Doty, Kevin Richard

2012-01-01T23:59:59.000Z

74

Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)  

Science Conference Proceedings (OSTI)

We present an efficient pipeline enabling high-throughput analysis of protein structure in solution with small angle X-ray scattering (SAXS). Our SAXS pipeline combines automated sample handling of microliter volumes, temperature and anaerobic control, rapid data collection and data analysis, and couples structural analysis with automated archiving. We subjected 50 representative proteins, mostly from Pyrococcus furiosus, to this pipeline and found that 30 were multimeric structures in solution. SAXS analysis allowed us to distinguish aggregated and unfolded proteins, define global structural parameters and oligomeric states for most samples, identify shapes and similar structures for 25 unknown structures, and determine envelopes for 41 proteins. We believe that high-throughput SAXS is an enabling technology that may change the way that structural genomics research is done.

Hura, Greg L.; Menon, Angeli L.; Hammel, Michal; Rambo, Robert P.; Poole II, Farris L.; Tsutakawa, Susan E.; Jenney Jr, Francis E.; Classen, Scott; Frankel, Kenneth A.; Hopkins, Robert C.; Yang, Sungjae; Scott, Joseph W.; Dillard, Bret D.; Adams, Michael W. W.; Tainer, John A.

2009-07-20T23:59:59.000Z

75

High-throughput data mined prediction of inorganic compounds and computational discovery of new lithium-ion battery cathode materials  

E-Print Network (OSTI)

The ability to computationally predict the properties of new materials, even prior to their synthesis, has been made possible due to the current accuracy of modern ab initio techniques. In some cases, high-throughput ...

Hautier, Geoffroy (Geoffroy T. F.)

2011-01-01T23:59:59.000Z

76

Evaluation of Tavorite-Structured Cathode Materials for Lithium-Ion Batteries Using High-Throughput Computing  

E-Print Network (OSTI)

Cathode materials with structure similar to the mineral tavorite have shown promise for use in lithium-ion batteries, but this class of materials is relatively unexplored. We use high-throughput density-functional-theory ...

Mueller, Tim

77

High Throughput Plasmid Sequencing with Illumina and CLC Bio (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)  

Science Conference Proceedings (OSTI)

Ajay Athavale (Monsanto) presents "High Throughput Plasmid Sequencing with Illumina and CLC Bio" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

Athavale, Ajay [Monsanto

2012-06-01T23:59:59.000Z

78

High Throughput Computing Impact on Meta Genomics (Metagenomics Informatics Challenges Workshop: 10K Genomes at a Time)  

Science Conference Proceedings (OSTI)

This presentation includes a brief background on High Throughput Computing, correlating gene transcription factors, optical mapping, genotype to phenotype mapping via QTL analysis, and current work on next gen sequencing.

Gore, Brooklin [Morgridge Institute for Research

2011-10-12T23:59:59.000Z

79

Coev2Net: a computational framework for boosting confidence in high-throughput protein-protein interaction datasets  

E-Print Network (OSTI)

Improving the quality and coverage of the protein interactome is of tantamount importance for biomedical research, particularly given the various sources of uncertainty in high-throughput techniques. We introduce a ...

Hosur, Raghavendra

80

Advances in high-throughput speed, low-latency communication for embedded instrumentation ( 7th Annual SFAF Meeting, 2012)  

Science Conference Proceedings (OSTI)

Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Jordan, Scott [Physik Instrumente

2012-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

High-Throughput Asynchronous Pipelines for Fine-Grain Dynamic Datapaths  

E-Print Network (OSTI)

This paper introduces several new asynchronous pipeline designs which offer high throughput as well as low latency. The designs target dynamic datapaths, both dualrail as well as single-rail. The new pipelines are latchfree and therefore are particularly well-suited for fine-grain pipelining, i.e., where each pipeline stage is only a single gate deep. The pipelines employ new control structures and protocols aimed at reducing the handshaking delay, the principal impediment to achieving high throughput in asynchronous pipelines. As a test vehicle, a 4-bit FIFO was designed using 0.6 micron technology. The results of careful HSPICE simulations of the FIFO designs are very encouraging. The dualrail designs deliver a throughput of up to 860 million data items per second. This performance represents an improvement by a factor of 2 over a widely-used comparable approach by Williams [16]. The new single-rail designs deliver a throughput of up to 1208 million data items per second.

Montek Singh; Steven M. Nowick

2000-01-01T23:59:59.000Z

82

Development of a high-throughput microfluidic integrated microarray for the detection of chimeric bioweapons.  

SciTech Connect

The advancement of DNA cloning has significantly augmented the potential threat of a focused bioweapon assault, such as a terrorist attack. With current DNA cloning techniques, toxin genes from the most dangerous (but environmentally labile) bacterial or viral organism can now be selected and inserted into robust organism to produce an infinite number of deadly chimeric bioweapons. In order to neutralize such a threat, accurate detection of the expressed toxin genes, rather than classification on strain or genealogical decent of these organisms, is critical. The development of a high-throughput microarray approach will enable the detection of unknowns chimeric bioweapons. The development of a high-throughput microarray approach will enable the detection of unknown bioweapons. We have developed a unique microfluidic approach to capture and concentrate these threat genes (mRNA's) upto a 30 fold concentration. These captured oligonucleotides can then be used to synthesize in situ oligonucleotide copies (cDNA probes) of the captured genes. An integrated microfluidic architecture will enable us to control flows of reagents, perform clean-up steps and finally elute nanoliter volumes of synthesized oligonucleotides probes. The integrated approach has enabled a process where chimeric or conventional bioweapons can rapidly be identified based on their toxic function, rather than being restricted to information that may not identify the critical nature of the threat.

Sheppod, Timothy; Satterfield, Brent; Hukari, Kyle W.; West, Jason A. A.; Hux, Gary A.

2006-10-01T23:59:59.000Z

83

Managing System of Systems Requirements with a Requirements Screening Group  

SciTech Connect

Figuring out an effective and efficient way to manage not only your Requirements Baseline, but also the development of all your individual requirements during a Programs/Projects Conceptual and Development Life Cycle Stages can be both daunting and difficult. This is especially so when you are dealing with a complex and large System of Systems (SoS) Program with potentially thousands and thousands of Top Level Requirements as well as an equal number of lower level System, Subsystem and Configuration Item requirements that need to be managed. This task is made even more overwhelming when you have to add in integration with multiple requirements development teams (e.g., Integrated Product Development Teams (IPTs)) and/or numerous System/Subsystem Design Teams. One solution for tackling this difficult activity on a recent large System of Systems Program was to develop and make use of a Requirements Screening Group (RSG). This group is essentially a Team made up of co-chairs from the various Stakeholders with an interest in the Program of record that are enabled and accountable for Requirements Development on the Program/Project. The RSG co-chairs, often with the help of individual support team, work together as a Program Board to monitor, make decisions on, and provide guidance on all Requirements Development activities during the Conceptual and Development Life Cycle Stages of a Program/Project. In addition, the RSG can establish and maintain the Requirements Baseline, monitor and enforce requirements traceability across the entire Program, and work with other elements of the Program/Project to ensure integration and coordination.

Ronald R. Barden

2012-07-01T23:59:59.000Z

84

Screening Pumping Systems for Energy Savings Opportunities  

E-Print Network (OSTI)

In most industrial settings, energy consumed by pumping systems is responsible for a major part of the overall electricity bill. In some cases, the energy is used quite efficiently; in others, it is not. Facility operators may be very familiar with pumping system equipment controllability, reliability, and availability, but only marginally aware of system efficiency. But there are some good reasons to increase that awareness: 1) As budgets shrink and the intensity of both domestic and international competition increases, the pressure to find additional ways of reducing costs will grow. 2) The reliability of pumps correlates with pump efficiency; that is, pumps operated near the design, or best efficiency point, will tend to perform more reliably and with greater availability. 3) The questions of whether global warming is truly occurring, and if it is, whether humankind's activities play a significant role may both be debatable. But there is no debating the fact that there are finite energy resources, particularly of the fossil fuel variety, on the earth. If we are to be counted as good stewards, then careful, if not frugal resource use is important. The cost of energy consumed by pumps usually dominates the pump life cycle cost. But many end users, already stretched to support day-to-day facility operations, lack the time and resources to perform a methodical engineering study of, in some cases, hundreds of pumps within their facilities to understand the energy costs and the potential opportunity for reduction. Under the auspices of the Department of Energy's (DOE) Motor Challenge Program, prescreening guidance documents and a computer program called PSAT (Pumping System Assessment Tool) have been developed to help end users, consultants, and equipment distributors recognize, both qualitatively and quantitatively, pumping system efficiency improvement opportunities. This paper describes the general methodologies employed and shows case study examples of the prescreening and software application.

Casada, D.

1999-05-01T23:59:59.000Z

85

High throughput low power decoder architectures for low density parity check codes  

E-Print Network (OSTI)

A high throughput scalable decoder architecture, a tiling approach to reduce the complexity of the scalable architecture, and two low power decoding schemes have been proposed in this research. The proposed scalable design is generated from a serial architecture by scaling the combinational logic; memory partitioning and constructing a novel H matrix to make parallelization possible. The scalable architecture achieves a high throughput for higher values of the parallelization factor M. The switch logic used to route the bit nodes to the appropriate checks is an important constituent of the scalable architecture and its complexity is high with higher M. The proposed tiling approach is applied to the scalable architecture to simplify the switch logic and reduce gate complexity. The tiling approach generates patterns that are used to construct the H matrix by repeating a fixed number of those generated patterns. The advantages of the proposed approach are two-fold. First, the information stored about the H matrix is reduced by onethird. Second, the switch logic of the scalable architecture is simplified. The H matrix information is also embedded in the switch and no external memory is needed to store the H matrix. Scalable architecture and tiling approach are proposed at the architectural level of the LDPC decoder. We propose two low power decoding schemes that take advantage of the distribution of errors in the received packets. Both schemes use a hard iteration after a fixed number of soft iterations. The dynamic scheme performs X soft iterations, then a parity checker cHT that computes the number of parity checks in error. Based on cHT value, the decoder decides on performing either soft iterations or a hard iteration. The advantage of the hard iteration is so significant that the second low power scheme performs a fixed number of iterations followed by a hard iteration. To compensate the bit error rate performance, the number of soft iterations in this case is higher than that of those performed before cHT in the first scheme.

Selvarathinam, Anand Manivannan

2005-08-01T23:59:59.000Z

86

PIPA: A High-Throughput Pipeline for Protein Function Annotation Chenggang Yu, Valmik Desai, Nela Zavaljevski, and Jaques Reifman  

E-Print Network (OSTI)

PIPA: A High-Throughput Pipeline for Protein Function Annotation Chenggang Yu, Valmik Desai, Nela of multisource predictions. We developed Pipeline for Protein Annotation (PIPA), a genome-wide protein function annotation pipeline that runs in a high-performance computing environment. PIPA integrates different tools

87

PIPELINED PARALLEL ARCHITECTURE FOR HIGH THROUGHPUT MAP DETECTORS Ruwan Ratnayake, Gu-Yeon Wei and Aleksandar Kavcic  

E-Print Network (OSTI)

PIPELINED PARALLEL ARCHITECTURE FOR HIGH THROUGHPUT MAP DETECTORS Ruwan Ratnayake, Gu-Yeon Wei performance close to the channel capacity limits. Deep pipelined architecture for the forward only method, where as FB-BCJR only allow sequential state metric computations. Parallelism facilitates pipelining, re

Kavcic, Aleksandar

88

PIP: a connection-oriented, multi-hop, multi-channel TDMA-based MAC for high throughput bulk transfer  

Science Conference Proceedings (OSTI)

In this paper, we consider the goal of achieving high throughput in a wireless sensor network. Our work is set in the context of those wireless sensor network applications which collect and transfer bulk data. We present PIP (Packets in Pipe), a MAC ... Keywords: MAC, TDMA, bulk data transfer, pipelining, throughput optimization, wireless sensor network applications

Bhaskaran Raman; Kameswari Chebrolu; Sagar Bijwe; Vijay Gabale

2010-11-01T23:59:59.000Z

89

High-throughput Characterization of Porous Materials Using Graphics Processing Units  

Science Conference Proceedings (OSTI)

We have developed a high-throughput graphics processing units (GPU) code that can characterize a large database of crystalline porous materials. In our algorithm, the GPU is utilized to accelerate energy grid calculations where the grid values represent interactions (i.e., Lennard-Jones + Coulomb potentials) between gas molecules (i.e., CH$_{4}$ and CO$_{2}$) and material's framework atoms. Using a parallel flood fill CPU algorithm, inaccessible regions inside the framework structures are identified and blocked based on their energy profiles. Finally, we compute the Henry coefficients and heats of adsorption through statistical Widom insertion Monte Carlo moves in the domain restricted to the accessible space. The code offers significant speedup over a single core CPU code and allows us to characterize a set of porous materials at least an order of magnitude larger than ones considered in earlier studies. For structures selected from such a prescreening algorithm, full adsorption isotherms can be calculated by conducting multiple grand canonical Monte Carlo simulations concurrently within the GPU.

Kim, Jihan; Martin, Richard L.; Ruebel, Oliver; Haranczyk, Maciej; Smit, Berend

2012-03-19T23:59:59.000Z

90

High-throughput liquid-absorption air-sampling apparatus and methods  

DOE Patents (OSTI)

A portable high-throughput liquid-absorption air sampler [PHTLAAS] has an asymmetric air inlet through which air is drawn upward by a small and light-weight centrifugal fan driven by a direct current motor that can be powered by a battery. The air inlet is so configured as to impart both rotational and downward components of motion to the sampled air near said inlet. The PHTLAAS comprises a glass tube of relatively small size through which air passes at a high rate in a swirling, highly turbulent motion, which facilitates rapid transfer of vapors and particulates to a liquid film covering the inner walls of the tube. The pressure drop through the glass tube is <10 cm of water, usually <5 cm of water. The sampler's collection efficiency is usually >20% for vapors or airborne particulates in the 2-3.mu. range and >50% for particles larger than 4.mu.. In conjunction with various analyzers, the PHTLAAS can serve to monitor a variety of hazardous or illicit airborne substances, such as lead-containing particulates, tritiated water vapor, biological aerosols, or traces of concealed drugs or explosives.

Zaromb, Solomon (95706 William Dr., Hinsdale, IL 60521)

2000-01-01T23:59:59.000Z

91

A new implementation of high-throughput five-dimensional clone pooling strategy for BAC library screening  

E-Print Network (OSTI)

PP), column super-pools (CSP), and row super-pools (RSP) isa positive plate RSP, plate CSP, clone RP and clone CP forof plate RSP and plate CSP in the super pool 2-D design

You, Frank M; Luo, Ming-Cheng; Xu, Kenong; Deal, Karin R; Anderson, Olin D; Dvorak, Jan

2010-01-01T23:59:59.000Z

92

DOVIS: A Tool for High-throughput Virtual Screening Xiaohui Jiang, Kamal Kumar, Anders Wallqvist, and Jaques Reifman  

E-Print Network (OSTI)

on and capture the top percentage of high-scoring ligands are high performance computing (HPC) platforms

93

Optimization of density functional tight-binding and classical reactive molecular dynamics for high-throughput simulations of carbon materials  

Science Conference Proceedings (OSTI)

Carbon materials and nanostructures (fullerenes, nanotubes) are promising building blocks of nanotechnology. Potential applications include optical and electronic devices, sensors, and nano-scale machines. The multiscale character of processes related ... Keywords: ACM proceedings, BLAS, Cray XT5, LAPACK, advanced materials, density-functional tight binding, high-throughput, linear algebra, material science, molecular dynamics, multiscale-modeling, quantum chemistry, scientific libraries, scientific-computing

Jacek Jakowski; Bilel Hadri; Steven J. Stuart; Predrag Krstic; Stephan Irle; Dulma Nugawela; Sophya Garashchuk

2012-07-01T23:59:59.000Z

94

Integrated crystal mounting and alignment system for high-throughput biological crystallography  

DOE Patents (OSTI)

A method and apparatus for the transportation, remote and unattended mounting, and visual alignment and monitoring of protein crystals for synchrotron generated x-ray diffraction analysis. The protein samples are maintained at liquid nitrogen temperatures at all times: during shipment, before mounting, mounting, alignment, data acquisition and following removal. The samples must additionally be stably aligned to within a few microns at a point in space. The ability to accurately perform these tasks remotely and automatically leads to a significant increase in sample throughput and reliability for high-volume protein characterization efforts. Since the protein samples are placed in a shipping-compatible layered stack of sample cassettes each holding many samples, a large number of samples can be shipped in a single cryogenic shipping container.

Nordmeyer, Robert A. (San Leandro, CA); Snell, Gyorgy P. (Richmond, CA); Cornell, Earl W. (Antioch, CA); Kolbe, William F. (Moraga, CA); Yegian, Derek T. (Oakland, CA); Earnest, Thomas N. (Berkeley, CA); Jaklevich, Joseph M. (Lafayette, CA); Cork, Carl W. (Walnut Creek, CA); Santarsiero, Bernard D. (Chicago, IL); Stevens, Raymond C. (La Jolla, CA)

2007-09-25T23:59:59.000Z

95

A titer plate-based polymer microfluidic platform for high throughput nucleic acid purification  

E-Print Network (OSTI)

SPRI reactor SPRI technologies are a solid-phase capture approach, so maximizing the extraction bed. Chem. 74 (12), 2623 (2002) Society for Biomolecular Screening (SBS), Microplate Standards Development Committee, ANSI/SBS 1-2004 (SBS, Microplate Standards Development Committee, Danbury, CT, 2004) F.M. White

Lee, Jeong-Bong

96

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage  

E-Print Network (OSTI)

low volume, energy efficient hydrogen storage system if fuelof Energy (DOE) for on-board hydrogen storage. However,hydrogen storage system as defined by the Department of Energy.

Barcelo, Steven James

2009-01-01T23:59:59.000Z

97

System Architectures Enabling Reconfigurable Laboratory-Automation Systems  

Science Conference Proceedings (OSTI)

As many biopharma companies fill their drug-discovery pipeline with new blockbuster candidates every year, the integration techniques employed become more critical. In the biopharma industry, high throughput screening (HTS) is an essential function to ...

H. Ozgur Unver

2011-11-01T23:59:59.000Z

98

Research Leading to High Throughput Manufacturing of Thin-Film CdTe PV Modules: Annual Technical Report, September 2003-September 2004  

DOE Green Energy (OSTI)

First Solar is actively commercializing CdTe-based thin-film photovoltaics. During the past year, major additions of production capability have been completed, as well as process improvements to achieve higher throughput and efficiency and greater durability. This report presents the results of Phase II of the subcontract, entitled ''Research Leading to High Throughput Manufacturing of Thin-Film CdTe PV Modules.'' The subcontract supports several important aspects needed for high-volume manufacturing of high-efficiency modules, including exploration of large-area advanced front-contact window layers, improvements of the semiconductor deposition system, advancement in understanding of post-deposition processing steps and accelerated life testing methods, and progress in the environmental, health and safety programs. Work under this subcontract contributes to the overall manufacturing operation. During Phase II, average module efficiency (total area) on the production line was improved from 7.9% to 8.6% due primarily to process optimization. At the same, time production volume for commercial sales increased from 2.5 MW in 2003 to an estimated 6 MW in 2004. Much of the new 25 MW/yr production line has been qualified, and production volume is steadily increasing.

Powell, R. C.

2004-12-01T23:59:59.000Z

99

Real-time statistical saliency using high throughput circuit design and its applications in psychophysical study  

E-Print Network (OSTI)

Using low level video data, features can be extracted from images to predict search time and statistical saliency in a way that models the human visual system. The statistical saliency model helps explain how visual search ...

Blau, David A

2007-01-01T23:59:59.000Z

100

High-Throughput Proteomics Using High Efficiency Multiple-Capillary Liquid Chromatography With On-Line High-Performance ESI FTICR Mass Spectrometry  

Science Conference Proceedings (OSTI)

We report on the design and application of a high-efficiency multiple-capillary liquid chromatography (LC) system for high-throughput proteome analysis. The multiple-capillary LC system was operated at the pressure of 10,000 psi using commercial LC pumps to deliver the mobile phase and newly developed passive feedback valves to switch the mobile phase flow and introduce samples. The multiple-capillary LC system was composed of several serially connected dual-capillary column devices. The dual-capillary column approach was designed to eliminate the time delay for regeneration (or equilibrium) of the capillary column after its use under the mobile phase gradient condition (i.e. one capillary column was used in separation and the other was washed using mobile phase A). The serially connected dual-capillary columns and ESI sources were operated independently, and could be used for either''backup'' operation or with other mass spectrometer(s). This high-efficiency multiple-capillary LC system uses switching valves for all operations and is highly amenable to automation. The separations efficiency of dual-capillary column device, optimal capillary dimensions (column length and packed particle size), suitable mobile phases for electrospray, and the capillary re-generation were investigated. A high magnetic field (11.5 tesla) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer was coupled on-line with this high-efficiency multiple-capillary LC system through an electrospray ionization source. The capillary LC provided a peak capacity of {approx}600, and the 2-D capillary LC-FTICR provided a combined resolving power of > 6 x 10 7 polypeptide isotopic distributions. For yeast cellular tryptic digests, > 100,000 polypeptides were typically detected, and {approx}1,000 proteins can be characterized in a single run.

Shen, Yufeng (BATTELLE (PACIFIC NW LAB)); Tolic, Nikola (BATTELLE (PACIFIC NW LAB)); Zhao, Rui (ASSOC WESTERN UNIVERSITY); Pasa Tolic, Ljiljana (BATTELLE (PACIFIC NW LAB)); Li, Lingjun (Illinois Univ Of-Urbana/Champa); Berger, Scott J. (ASSOC WESTERN UNIVERSITY); Harkewicz, Richard (BATTELLE (PACIFIC NW LAB)); Anderson, Gordon A. (BATTELLE (PACIFIC NW LAB)); Belov, Mikhail E. (BATTELLE (PACIFIC NW LAB)); Smith, Richard D. (BATTELLE (PACIFIC NW LAB))

2000-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Versatile refresh: low complexity refresh scheduling for high-throughput multi-banked eDRAM  

Science Conference Proceedings (OSTI)

Multi-banked embedded DRAM (eDRAM) has become increasingly popular in high-performance systems. However, the data retention problem of eDRAM is exacerbated by the larger number of banks and the high-performance environment in which it is deployed: The ... Keywords: embedded DRAM, memory refresh scheduling, multi-banked

Mohammad Alizadeh; Adel Javanmard; Shang-Tse Chuang; Sundar Iyer; Yi Lu

2012-06-01T23:59:59.000Z

102

Optima MDxt: A high throughput 335 keV mid-dose implanter  

SciTech Connect

The continuing demand for both energy purity and implant angle control along with high wafer throughput drove the development of the Axcelis Optima MDxt mid-dose ion implanter. The system utilizes electrostatic scanning, an electrostatic parallelizing lens and an electrostatic energy filter to produce energetically pure beams with high angular integrity. Based on field proven components, the Optima MDxt beamline architecture offers the high beam currents possible with singly charged species including arsenic at energies up to 335 keV as well as large currents from multiply charged species at energies extending over 1 MeV. Conversely, the excellent energy filtering capability allows high currents at low beam energies, since it is safe to utilize large deceleration ratios. This beamline is coupled with the >500 WPH capable endstation technology used on the Axcelis Optima XEx high energy ion implanter. The endstation includes in-situ angle measurements of the beam in order to maintain excellent beam-to-wafer implant angle control in both the horizontal and vertical directions. The Optima platform control system provides new generation dose control system that assures excellent dosimetry and charge control. This paper will describe the features and technologies that allow the Optima MDxt to provide superior process performance at the highest wafer throughput, and will provide examples of the process performance achievable.

Eisner, Edward; David, Jonathan; Justesen, Perry; Kamenitsa, Dennis; McIntyre, Edward; Rathmell, Robert; Ray, Andrew; Rzeszut, Richard [Axcelis Technologies, Inc., 108 Cherry Hill Drive, Beverly, MA 01915 (United States)

2012-11-06T23:59:59.000Z

103

Conversion of forest residues to a methane-rich gas in a high-throughput gasifier  

DOE Green Energy (OSTI)

Research was conducted in a process research unit to develop an entrained bed gasifier which is supplied heat by recirculating a stream of sand between a separate combustion vessel and the gasifier. The char remaining after gasification of the wood provides the fuel for the combustor. The research program was conducted in two phases. In the first phase, a 6 in. I.D. gasifier was used to establish the feasibility of the concept for a wide variety of biomass feeds. The second phase of the program was conducted with a 10 in. I.D. gasifier, and a fully automated feeder system, to evaluate gasifier performance at very high feed rates. The experimental results were used to develop design parameters and detailed energy and material balances for a conceptual plant. A preliminary cost analysis is presented in the report based on the conceptual design. 5 refs., 24 figs., 13 tabs.

Feldmann, H.F.; Paisley, M.A.; Appelbaum, H.R.; Taylor, D.R.

1988-05-01T23:59:59.000Z

104

Research Leading to High Throughput Processing of Thin-Film CdTe PV Module: Phase I Annual Report, October 2003 (Revised)  

DOE Green Energy (OSTI)

Work under this subcontract contributes to the overall manufacturing operation. During Phase I, average module efficiency on the line was improved from 7.1% to 7.9%, due primarily to increased photocurrent resulting from a decrease in CdS thickness. At the same time, production volume for commercial sale increased from 1.5 to 2.5 MW/yr. First Solar is committed to commercializing CdTe-based thin-film photovoltaics. This commercialization effort includes a major addition of floor space and equipment, as well as process improvements to achieve higher efficiency and greater durability. This report presents the results of Phase I of the subcontract entitled''Research Leading to High Throughput Processing of Thin-Film CdTe PV Modules.'' The subcontract supports several important aspects needed to begin high-volume manufacturing, including further development of the semiconductor deposition reactor, advancement of accelerated life testing methods and understanding, and improvements to th e environmental, health, and safety programs. Progress in the development of the semiconductor deposition reactor was made in several areas. First, a new style of vapor transport deposition distributor with simpler operational behavior and the potential for improved cross-web uniformity was demonstrated. Second, an improved CdS feed system that will improve down-web uniformity was developed. Third, the core of a numerical model of fluid and heat flow within the distributor was developed, including flow in a 3-component gas system at high temperature and low pressure and particle sublimation.

Powell, R. C.; Meyers, P. V.

2004-02-01T23:59:59.000Z

105

Technology Support for High-Throughput Processing of Thin-Film CdTe PV Modules: Final Technical Report, April 1998 - October 2001  

DOE Green Energy (OSTI)

This report describes the significant progress made in four areas of this subcontract: process and equipment development; efficiency improvement; characterization and analysis; and environmental, health, and safety. As part of the process and equipment development effort, vapor-transport deposition (VTD) was implemented first on a 60-cm-web pilot-production system, then on a 120-cm-web high-throughput coater. Deposition of CdS and CdTe films at a throughput of 3 m2/min was demonstrated, and more than 56,000 plates (each 0.72 m2) were coated -- 16 times the total number coated prior to the start of the contract. Progress was also made in the conversion efficiency and yield of both standard and next-generation modules, with data from more than 3000 sequentially deposited modules having an average total-area conversion efficiency of 7% and next-generation modules produced with efficiency as high as 9.3% (10.15% aperture-area efficiency as measured by NREL). Successful implementation o f in-situ CdS thickness measurements was important to progress in thickness uniformity and control. Net CdTe material utilization of 82% was demonstrated. The ability to raise the utilization further was shown with the demonstration of inherent CdS and CdTe material utilizations of over 90%. Post-CdTe-deposition process development, which included process space exploration and problem diagnosis, was an important part of advances in efficiency and yield. As part of the efficiency-improvement task, research was done on cells and modules with reduced CdS thickness to increase photocurrent.

Rose, D. H.; Powell, R. C.

2002-04-01T23:59:59.000Z

106

High-Throughput Genetic Identification of Functionally Important Regions of the Yeast DEAD-Box Protein Mss116p  

Science Conference Proceedings (OSTI)

The Saccharomyces cerevisiae DEAD-box protein Mss116p is a general RNA chaperone that functions in splicing mitochondrial group I and group II introns. Recent X-ray crystal structures of Mss116p in complex with ATP analogs and single-stranded RNA show that the helicase core induces a bend in the bound RNA, as in other DEAD-box proteins, while a C-terminal extension (CTE) induces a second bend, resulting in RNA crimping. Here, we illuminate these structures by using high-throughput genetic selections, unigenic evolution, and analyses of in vivo splicing activity to comprehensively identify functionally important regions and permissible amino acid substitutions throughout Mss116p. The functionally important regions include those containing conserved sequence motifs involved in ATP and RNA binding or interdomain interactions, as well as previously unidentified regions, including surface loops that may function in protein-protein interactions. The genetic selections recapitulate major features of the conserved helicase motifs seen in other DEAD-box proteins but also show surprising variations, including multiple novel variants of motif III (SAT). Patterns of amino acid substitutions indicate that the RNA bend induced by the helicase core depends on ionic and hydrogen-bonding interactions with the bound RNA; identify a subset of critically interacting residues; and indicate that the bend induced by the CTE results primarily from a steric block. Finally, we identified two conserved regions - one the previously noted post II region in the helicase core and the other in the CTE - that may help displace or sequester the opposite RNA strand during RNA unwinding.

Mohr, Georg; Del Campo, Mark; Turner, Kathryn G.; Gilman, Benjamin; Wolf, Rachel Z.; Lambowitz, Alan M. (Texas)

2012-03-15T23:59:59.000Z

107

A NOVEL LOW THERMAL BUDGET THIN-FILM POLYSILICON FABRICATION PROCESS FOR LARGE-AREA, HIGH-THROUGHPUT SOLAR CELL PRODUCTION  

DOE Green Energy (OSTI)

methods. The poly-Si solar cell structure and the performance have been examined. In principle, the new process is potentially applicable to produce large-area thin-film poly-Si solar cells at a high throughput and low cost. A critical issue in this process is to prevent the excessive dopant diffusion during crystallization. Process parameters and the cell structure have to be optimized to achieve the production goal.

Yue Kuo

2010-08-15T23:59:59.000Z

108

Abstract--Design aspects of a minimally invasive high-throughput automation system for radiation biodosimetry are  

E-Print Network (OSTI)

observed in exposed individuals following the incidents at Chernobyl [13] and Goiânia [14]. In this assay evaluation of immigrents from the vicinity of Chernobyl. International Journal of Radiation Biology, 1997. 72

109

High-Throughput Intermodal Container Terminals: Technical and Economic Analysis of a New Direct-Transfer System  

E-Print Network (OSTI)

storage or handling is required at the remote rail yard.remote rail yard. They include the capital costs for me handling

De Castilho, Bernardo J.

1992-01-01T23:59:59.000Z

110

High-Throughput Intermodal Container Terminals: Technical and Economic Analysis of a New Direct-Transfer System  

E-Print Network (OSTI)

interest in port and rail research Computer simulations have5.2.1. Microscopic-Level Research Topics Rail Technology Theor operates the rail yard. In this research, we do not make

De Castilho, Bernardo J.

1992-01-01T23:59:59.000Z

111

Screening study on high temperature energy transport systems  

SciTech Connect

The purpose of the study described in this document is to identify the options for transporting thermal energy over long distances. The study deals specifically and exclusively with high temperature (> 400/sup 0/C(752/sup 0/F)) energy for industrial use. Energy transport is seen as a potential solution to: high unit cost of small coal and nuclear steam generators, and opposition to siting of coal or nuclear plants near populated areas. The study is of a preliminary nature but covers many options including steam, molten salts, organics, and chemical heat pipes. The development status and potential problems of these and other energy transport methods are discussed. Energy transport concepts are compared on a fundamental level based on physical properties and also are subjected to an economic study. The economic study indicated that the chemical heat pipe, under a specific set of circumstances, appeared to be the least expensive for distances greater than about 32 km (20 miles). However, if the temperature of the energy was lowered, the heat transfer salt (sodium nitrate/nitrite) system would apparently be a better economic choice for less than about 80 km (50 miles). None of the options studied appear to be more attractive than small coal-fired boilers when the transport distance is over about 64 km (40 miles). Several recommendations are made for refining the analysis.

Graves, R.L.

1980-10-01T23:59:59.000Z

112

Hypertension screening Influenza immunization  

E-Print Network (OSTI)

Preventive services that providers and care systems must assess the need for and offer to each patient. These have the highest priority value (see Table 1) Alcohol abuse; hazardous and harmful drinking screening and brief counseling Aspirin chemoprophylaxis counseling Breast cancer screening Cervical cancer screening Chlamydia screening Colorectal cancer screening

S Ystems Improvement; Level I; Lipid Screening; Pneumococcal Immunization

2009-01-01T23:59:59.000Z

113

Environmental Measurement-While-Drilling System for Real-Time Field Screening of Contaminants  

SciTech Connect

Sampling during environmental drilling is essential to fully characterize the spatial distribution and migration of near surface contaminants. However, analysis of the samples is expensive and time-consuming: off-site laboratory analysis can take weeks or months. An alternative screening technology, Environmental Measurement-While-Drilling (EMWD), could save money and valuable time by quickly distinguishing between contaminated and uncontaminated areas. Real time measurements provided by an EMWD system enable on-the-spot decisions to be made regarding sampling strategies. The system also enhances worker safety and provides the added flexibility of being able to steer a drill bit in or out of hazardous zones.

Bishop, L.B.; Lockwood, G.J.; Normann, R.A.; Selph, M.M.; Williams, C.V.

1999-02-22T23:59:59.000Z

114

The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data  

E-Print Network (OSTI)

The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor system in mammalian cells, and it also has become a popular example for employing mathematical modeling to cellular signaling ...

Sorger, Peter K.

115

Modeling formalisms in Systems Biology  

E-Print Network (OSTI)

Systems Biology has taken advantage of computational tools and high-throughput experimental data to model several biological processes. These include signaling, gene regulatory, and metabolic networks. However, most of ...

Machado, Daniel

116

A NOVEL LOW THERMAL BUDGET THIN-FILM POLYSILICON FABRICATION PROCESS FOR LARGE-AREA, HIGH-THROUGHPUT SOLAR CELL PRODUCTION  

SciTech Connect

A novel thin-film poly-Si fabrication process has been demonstrated. This low thermal budget process transforms the single- and multi-layer amorphous silicon thin films into a poly-Si structure in one simple step over a pulsed rapid thermal annealing process with the enhancement of an ultrathin Ni layer. The complete poly-Si solar cell was fabricated in a short period of time without deteriorating the underneath glass substrate. The unique vertical crystallization process including the mechanism is discussed. Influences of the dopant type and process parameters on crystal structure will be revealed. The poly-Si film structure has been proved using TEM, XRD, Raman, and XPS methods. The poly-Si solar cell structure and the performance have been examined. In principle, the new process is potentially applicable to produce large-area thin-film poly-Si solar cells at a high throughput and low cost. A critical issue in this process is to prevent the excessive dopant diffusion during crystallization. Process parameters and the cell structure have to be optimized to achieve the production goal.

Yue Kuo

2010-08-15T23:59:59.000Z

117

HIV-1 entry inhibition by small-molecule CCR5 antagonists: A combined molecular modeling and mutant study using a high-throughput assay  

Science Conference Proceedings (OSTI)

Based on the attrition rate of CCR5 small molecule antagonists in the clinic the discovery and development of next generation antagonists with an improved pharmacology and safety profile is necessary. Herein, we describe a combined molecular modeling, CCR5-mediated cell fusion, and receptor site-directed mutagenesis approach to study the molecular interactions of six structurally diverse compounds (aplaviroc, maraviroc, vicriviroc, TAK-779, SCH-C and a benzyloxycarbonyl-aminopiperidin-1-yl-butane derivative) with CCR5, a coreceptor for CCR5-tropic HIV-1 strains. This is the first study using an antifusogenic assay, a model of the interaction of the gp120 envelope protein with CCR5. This assay avoids the use of radioactivity and HIV infection assays, and can be used in a high throughput mode. The assay was validated by comparison with other established CCR5 assays. Given the hydrophobic nature of the binding pocket several binding models are suggested which could prove useful in the rational drug design of new lead compounds.

Labrecque, Jean [Department of Biology, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States); Metz, Markus [Department of Chemistry, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States); Lau, Gloria; Darkes, Marilyn C.; Wong, Rebecca S.Y. [Department of Biology, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States); Bogucki, David; Carpenter, Bryon; Chen Gang; Li Tongshuang; Nan, Susan [Department of Chemistry, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States); Schols, Dominique [Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000, Leuven (Belgium); Bridger, Gary J. [Department of Chemistry, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States); Fricker, Simon P. [Department of Biology, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States); Skerlj, Renato T., E-mail: renato.skerlj@genzyme.co [Department of Chemistry, AnorMED Inc. now Genzyme Corporation, 500 Kendall Street, Cambridge, MA 02142 (United States)

2011-05-10T23:59:59.000Z

118

HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage  

NLE Websites -- All DOE Office Websites (Extended Search)

FLORIDA SOLAR ENERGY CENTER FLORIDA SOLAR ENERGY CENTER Creating Energy Independence Since 1975 A Research Institute of the University of Central Florida HT Combinatorial Screening of HT Combinatorial Screening of Novel Materials for High Capacity Novel Materials for High Capacity Hydrogen Storage Hydrogen Storage Ali T Ali T - - Raissi Raissi Director, Hydrogen & Fuel Cell R&D Director, Hydrogen & Fuel Cell R&D Division Division High Throughput/Combinatorial Analysis of Hydrogen Storage High Throughput/Combinatorial Analysis of Hydrogen Storage Materials Workshop, Bethesda, MD Materials Workshop, Bethesda, MD 26 June 2007 26 June 2007 This presentation does not contain any proprietary or confidential information 2 Objectives Objectives Develop (i.e. design, build, test and verify) a high

119

Novel System for Recalcitrance Screening Will Reduce Biofuels Production Costs, The Spectrum of Clean Energy Innovation (Fact Sheet)  

NLE Websites -- All DOE Office Websites (Extended Search)

This new system will allow researchers to much more rapidly screen large numbers of samples This new system will allow researchers to much more rapidly screen large numbers of samples and identify the most promising biomass feedstocks for higher efficiency and lower cost bio- fuels conversion processes. NREL will be screening thousands of variants of different biomass feedstocks to link genetic traits with environmental factors that can enhance biomass conver- sion efficiencies. Identifying the genes controlling the anatomical, chemical, and morphologi- cal features of biomass is essential to develop the next generation of low-cost, easily convert- ible biomass feedstocks. To identify superior performing biomass feedstocks using approaches that account for natural diversity and randomness, researchers must measure the cell wall chemistry and recalcitrance

120

Reproducible, High-Throughput Synthesis  

NLE Websites -- All DOE Office Websites (Extended Search)

J. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 10917-10921. (9) Han, G.; Mokari, T.; Ajo-Franklin, C.; Cohen, B. E. J. Am. Chem. Soc. 2008, 130, 15811-15813. (10) Colvin, V. L.;...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Use of Time-Aggregated Data in Economic Screening Analyses of Combined Heat and Power Systems  

Science Conference Proceedings (OSTI)

Combined heat and power (CHP) projects (also known as cogeneration projects) usually undergo a series of assessments and viability checks before any commitment is made. A screening analysis, with electrical and thermal loads characterized on an annual basis, may be performed initially to quickly determine the economic viability of the proposed project. Screening analyses using time-aggregated data do not reflect several critical cost influences, however. Seasonal and diurnal variations in electrical and thermal loads, as well as time-of-use utility pricing structures, can have a dramatic impact on the economics. A more accurate economic assessment requires additional detailed data on electrical and thermal demand (e.g., hourly load data), which may not be readily available for the specific facility under study. Recent developments in CHP evaluation tools, however, can generate the needed hourly data through the use of historical data libraries and building simulation. This article utilizes model-generated hourly load data for four potential CHP applications and compares the calculated cost savings of a CHP system when evaluated on a time-aggregated (i.e., annual) basis to the savings when evaluated on an hour-by-hour basis. It is observed that the simple, aggregated analysis forecasts much greater savings (i.e., greater economic viability) than the more detailed hourly analysis. The findings confirm that the simpler tool produces results with a much more optimistic outlook, which, if taken by itself, might lead to erroneous project decisions. The more rigorous approach, being more reflective of actual requirements and conditions, presents a more accurate economic comparison of the alternatives, which, in turn, leads to better decision risk management.

Hudson II, Carl Randy [ORNL

2004-09-01T23:59:59.000Z

122

Environmental Measurement While Drilling System for Real-Time Field Screening of Contaminants  

Science Conference Proceedings (OSTI)

Sampling during environmental drilling is essential to fully characterize the spatial distribution and migration of subsurface contaminants. However, analysis of the samples is expensive and time-consuming: off-site laboratory analysis can take weeks or months. Real-time information on environmental conditions, drill bit location and temperature during drilling is valuable in many environmental restoration operations. This type of information can be used to provide field screening data and improved efficiency of site characterization activities. The Environmental Measurement-While-Drilling (EMWD) System represents an innovative blending of new and existing technology in order to obtain real-time data during drilling. The system consists of two subsystems. The down-hole subsystem (at the drill bit) consists of sensors, a power supply, a signal conditioning and transmitter board, and a radio-frequency (RF) coaxial cable. The up-hole subsystem consists of a battery pack/coil, pickup coil, receiver, and personal computer. The system is compatible with fluid miser drill pipe, a directional drilling technique that uses minimal drilling fluids and generates little to no secondary waste. In EMWD, downhole sensors are located behind the drill bit and linked by a high-speed data transmission system to a computer at the surface. Sandia-developed Windows{trademark}-based software is used for data display and storage. As drilling is conducted, data is collected on the nature and extent of contamination, enabling on-the-spot decisions regarding drilling and sampling strategies. Initially, the downhole sensor consisted of a simple gamma radiation detector, a Geiger-Mueller tube (GMT). The design includes data assurance techniques to increase safety by reducing the probability of giving a safe indication when an unsafe condition exists. The EMWD system has been improved by the integration of a Gamma Ray Spectrometer (GRS) in place of the GMT. The GRS consists of a sodium iodide-thallium activated crystal coupled to a photomultiplier tube (PMT). The output of the PMT goes to a multichannel analyzer (MCA).The MCA data is transmitted to the surface via a signal conditioning and transmitter board similar to that used with the GMT. The EMWD system is described and the results of the GRS field tests and field demonstration are presented.

Lockwood, G.J.; Normann, R.A.; Williams, C.V.

1999-02-22T23:59:59.000Z

123

Plasma Screen Floating Mount  

Engineers at the Savannah River National Laboratory (SRNL) have invented a new mounting system for flat panel video technology. The plasma screen floating mount is a mounting system proven to eliminate vibration and dampen shock for mobile uses of ...

124

Co-hydrolysis of hydrothermal and dilute acid pretreated Populus slurries to support development of a high-throughput pretreatment system  

E-Print Network (OSTI)

Abstract Background: The BioEnergy Science Center (BESC)production. Background The BioEnergy Science Center (BESC)abbreviations used BESC: BioEnergy Science Center; HT: high-

Studer, Michael H; Brethauer, Simone; DeMartini, Jaclyn D; McKenzie, Heather L; Wyman, Charles E

2011-01-01T23:59:59.000Z

125

Screening Analysis : Volume 2, Impact Results (Columbia River System Operation Review).  

DOE Green Energy (OSTI)

Detailed results from all of the work groups are presented in this chapter. Ninety alternatives were analyzed during the screening process. Three of the alternative represent various base cases and are used for comparison purposes. The other 87 alternatives represent a wide variety of operational possibilities ranging from current operations to emphasizing a single river use to compromise operations that attempt to accommodate the multiple uses. Every possible alternative suggested during the screening phase was considered. Each alternative was given an abbreviated name, a number and assigned by ROSE to either the Corps (C) or BPA (B) for hydroregulation modeling. A list of the alternatives with its number and hydroregulation assignment is given below. The results in this chapter are presented in numerical order. The first 3 letters in the name identify which work group suggested the alternative. The format for the results includes a brief description of each alternative, a tabulation of the screening calculations organized by work group, and observations/comments on the alternative by the work groups. The description summarizes the key operational requirements for the alternative and was taken directly from the instructions given to the hydroregulation modelers.

Not Available

1992-06-01T23:59:59.000Z

126

Investigating the Operational Capabilities of Custom and Pedestrian Portal Monitoring Systems for Screening Livestock for Radioactive Contamination  

E-Print Network (OSTI)

Livestock and companion animals are valuable economically and emotionally in the economy of many states and to their citizens. In a radiological emergency situation, the loss of a large amount of livestock could be devastating to a state or national economy. If such an event occurred, there are currently no screening and decontamination protocols for the handling of livestock. This research investigated current policies and procedures for monitoring and decontamination of livestock and companion animals, as well as testing pedestrian portal monitors and a newly designed livestock portal capable of radionuclide identification. It was discovered that only ten states addressed companion animals or livestock anywhere in their emergency planning. Of the ten, only North Carolina, Washington, and a Massachusetts K9 unit had detailed decontamination procedures to report for companion animals. None of the states included detailed procedures for livestock. To address livestock screening, three pedestrian portal monitoring systems were tested in the field and lab trials the Johnson AM801, TSA TPM903A, and Ludlum 52-1-1. The systems were tested for position and count rate sensitivity with 1 and 5 Ci 137Cs sources placed on four locations on a steer. Factors such as operability and ease of use were also considered. All three systems would alarm when a 5 Ci 137Cs source was used and the occupancy sensor was triggered. The Johnson AM801 system was determined to be the most appropriate for use in livestock screening due to sensitive alarm algorithms, greater position discrimination with four detectors, and ease of adjustment for agricultural purposes. The last phase of this project included designing and constructing a portal system that included radionuclide identification capabilities. An array of six sodium iodide detectors was mounted on a panel and field-tested beside a cattle chute and in a walkway. The custom portal, the Bovine Screening Portal (BSP), observed increased count rates (>10?) from a 5 Ci 137Cs source in live time. The BSP demonstrated better detection and localization of the source and spectral identification capabilities compared to the commercially available pedestrian systems.

Erchinger, Jennifer

2013-05-01T23:59:59.000Z

127

Plant Phenotype Characterization System  

DOE Green Energy (OSTI)

This report is the final scientific report for the DOE Inventions and Innovations Project: Plant Phenotype Characterization System, DE-FG36-04GO14334. The period of performance was September 30, 2004 through July 15, 2005. The project objective is to demonstrate the viability of a new scientific instrument concept for the study of plant root systems. The root systems of plants are thought to be important in plant yield and thus important to DOE goals in renewable energy sources. The scientific study and understanding of plant root systems is hampered by the difficulty in observing root activity and the inadequacy of existing root study instrumentation options. We have demonstrated a high throughput, non-invasive, high resolution technique for visualizing plant root systems in-situ. Our approach is based upon low-energy x-ray radiography and the use of containers and substrates (artificial soil) which are virtually transparent to x-rays. The system allows us to germinate and grow plant specimens in our containers and substrates and to generate x-ray images of the developing root system over time. The same plant can be imaged at different times in its development. The system can be used for root studies in plant physiology, plant morphology, plant breeding, plant functional genomics and plant genotype screening.

Daniel W McDonald; Ronald B Michaels

2005-09-09T23:59:59.000Z

128

Phenotype Prediction Using Regularized Regression on Genetic Data in the DREAM5 Systems Genetics B Challenge  

E-Print Network (OSTI)

A major goal of large-scale genomics projects is to enable the use of data from high-throughput experimental methods to predict complex phenotypes such as disease susceptibility. The DREAM5 Systems Genetics B Challenge ...

Loh, Po-Ru

129

Development & Optimization of Materials and Processes for a Cost Effective Photoelectrochemical Hydrogen Production System  

DOE Green Energy (OSTI)

The overall project objective was to apply high throughput experimentation and combinatorial methods together with novel syntheses to discover and optimize efficient, practical, and economically sustainable materials for photoelectrochemical production of bulk hydrogen from water. Automated electrochemical synthesis and photoelectrochemical screening systems were designed and constructed and used to study a variety of new photoelectrocatalytic materials. We evaluated photocatalytic performance in the dark and under illumination with or without applied bias in a high-throughput manner and did detailed evaluation on many materials. Significant attention was given to ?-Fe2O3 based semiconductor materials and thin films with different dopants were synthesized by co-electrodeposition techniques. Approximately 30 dopants including Al, Zn, Cu, Ni, Co, Cr, Mo, Ti, Pt, etc. were investigated. Hematite thin films doped with Al, Ti, Pt, Cr, and Mo exhibited significant improvements in efficiency for photoelectrochemical water splitting compared with undoped hematite. In several cases we collaborated with theorists who used density functional theory to help explain performance trends and suggest new materials. The best materials were investigated in detail by X-ray diffraction (XRD), scanning electron microscopy (SEM), ultraviolet-visual spectroscopy (UV-Vis), X-ray photoelectron spectroscopy (XPS). The photoelectrocatalytic performance of the thin films was evaluated and their incident photon

Eric W. McFarland

2011-01-17T23:59:59.000Z

130

Exploring flexible strategies in engineering systems using screening models : applications to offshore petroleum projects  

E-Print Network (OSTI)

Engineering Systems, such as offshore petroleum exploration and production systems, generally require a significant amount of capital investment under various technical and market uncertainties. Choosing appropriate designs ...

Lin, Jijun, Ph. D. Massachusetts Institute of Technology

2009-01-01T23:59:59.000Z

131

Screening Analysis for the Environmental Risk Evaluation System Fiscal Year 2011 Report Environmental Effects of Offshore Wind Energy  

SciTech Connect

Potential environmental effects of offshore wind (OSW) energy development are not well understood, and yet regulatory agencies are required to make decisions in spite of substantial uncertainty about environmental impacts and their long-term consequences. An understanding of risks associated with interactions between OSW installations and avian and aquatic receptors, including animals, habitats, and ecosystems, can help define key uncertainties and focus regulatory actions and scientific studies on interactions of most concern. During FY 2011, Pacific Northwest National Laboratory (PNNL) scientists adapted and applied the Environmental Risk Evaluation System (ERES), first developed to examine the effects of marine and hydrokinetic energy devices on aquatic environments, to offshore wind development. PNNL scientists conducted a risk screening analysis on two initial OSW cases: a wind project in Lake Erie and a wind project off the Atlantic coast of the United States near Atlantic City, New Jersey. The screening analysis revealed that top-tier stressors in the two OSW cases were the dynamic effects of the device (e.g., strike), accidents/disasters, and effects of the static physical presence of the device, such as alterations in bottom habitats. Receptor interactions with these stressors at the highest tiers of risk were dominated by threatened and endangered animals. Risk to the physical environment from changes in flow regime also ranked high. Peer review of this process and results will be conducted during FY 2012. The ERES screening analysis provides an assessment of the vulnerability of environmental receptors to stressors associated with OSW installations; a probability analysis is needed to determine specific risk levels to receptors. As more data become available that document effects of offshore wind farms on specific receptors in U.S. coastal and Great Lakes waters, probability analyses will be performed.

Copping, Andrea E.; Hanna, Luke A.

2011-11-01T23:59:59.000Z

132

Some potential material supply constraints in the deployment of photovoltaic solar electric systems. (A preliminary screening to identify critical materials)  

DOE Green Energy (OSTI)

The objectives of this study are to: (1) identify potential material supply constraints which could seriously impede the large scale installation of photovoltaic (PV) systems; (2) provide a functional description of materials used in the construction of selected photovoltaic systems in computerized format suitable for interactive updating in workshops or for future reviews; (3) provide a data base of statistics and production processes in machine accessible format for making this assessment and supporting future PV assessments; and (4) show the sensitivity of potential shortages to the size of the PV implementation scenario. The scope of the study includes the screening of 13 photovoltaic cells in a total of 15 system designs. Some cells are also included in concentrating systems at 500 suns and 30 suns. The systems all are based on the substitutions of various cells and concentrator devices into designs based on the Meade, Nebraska 25 kW installation. The system designs all include energy storage but the effect of deleting energy storage is also examined. The study methodology, results, and recommendations are presented in detail. (WHK)

Watts, R.L.; Gurwell, W.E.; Bloomster, C.H.; Smith, S.A.; Nelson, T.A.; Pawlewicz, W.W.

1978-09-01T23:59:59.000Z

133

Design, construction and commissioning of the Thermal Screen Control System for the CMS Tracker detector at CERN  

E-Print Network (OSTI)

The CERN (European Organization for Nuclear Research) laboratory is currently building the Large Hadron Collider (LHC). Four international collaborations have designed (and are now constructing) detectors able to exploit the physics potential of this collider. Among them is the Compact Muon Solenoid (CMS), a general purpose detector optimized for the search of Higgs boson and for physics beyond the Standard Model of fundamental interactions between elementary particles. This thesis presents, in particular, the design, construction, commissioning and test of the control system for a screen that provides a thermal separation between the Tracker and ECAL (Electromagnetic CALorimeter) detector of CMS (Compact Muon Solenoid experiment). Chapter 1 introduces the new challenges posed by these installations and deals, more in detail, with the Tracker detector of CMS. The size of current experiments for high energy physics is comparable to that of a small industrial plant: therefore, the techniques used for controls a...

Carrone, E; Tsirou, A

134

Estimation of Thermal Resistance from Room Temperature Electrical Resistance Measurements for Different LHC Beam Screen Support Systems  

E-Print Network (OSTI)

In this note the thermal resistance between the LHC beam screen and cold bore is estimated from room temperature electrical resistance measurements. The results indicate that the beam screen without supports should have a comparable, if not better, thermal performance than the one with the existing spring supports. This prediction from electrical resistance measurements is confirmed by recent preliminary thermal measurements.

Jenninger, B

1999-01-01T23:59:59.000Z

135

M2 priority screening system for near-term activities: Project documentation. Final report December 11, 1992--May 31, 1994  

Science Conference Proceedings (OSTI)

From May through August, 1993, the M-2 Group within M Division at LANL conducted with the support of the LANL Integration and Coordination Office (ICO) and Applied Decision Analysis, Inc. (ADA), whose purpose was to develop a system for setting priorities among activities. This phase of the project concentrated on prioritizing near-tenn activities (i.e., activities that must be conducted in the next six months) necessary for setting up this new group. Potential future project phases will concentrate on developing a tool for setting priorities and developing annual budgets for the group`s operations. The priority screening system designed to address the near-term problem was developed, applied in a series of meeting with the group managers, and used as an aid in the assignment of tasks to group members. The model was intended and used as a practical tool for documenting and explaining decisions about near-term priorities, and not as a substitute for M-2 management judgment and decision-making processes.

NONE

1993-08-12T23:59:59.000Z

136

High-throughput manufacturing of thin-film CdS/CdTe photovoltaic modules. Annual subcontract report, 16 September 1996--15 January 1998  

DOE Green Energy (OSTI)

Cadmium telluride (CdTe) is recognized as one of the leading materials for low-cost photovoltaic modules. Solar Cells, Inc., has developed this technology and is scaling its pilot production capabilities to a multi-megawatt level. The Photovoltaic Manufacturing Technology (PVMaT) subcontract supports these efforts. Activities during the third phase of the program concentrated on process development, equipment design and testing, quality assurance, ES and H programs, and large-scale next-generation coating-system prototype development. These efforts broadly addressed the issues of the manufacturing process for producing thin-film, monolithic CdS/CdTe photovoltaic modules.

Sandwisch, D.W. [Solar Cells, Inc., Toledo, OH (United States)

1998-08-01T23:59:59.000Z

137

Technology support for initiation of high-throughput processing of thin-film CdTe PV modules. Phase 1 technical report, March 14, 1995--March 13, 1996  

DOE Green Energy (OSTI)

Progress has been made in the important areas of stability, advanced deposition techniques, efficiency, the back contact, no-contact film diagnostics (photoluminescence) and Cd waste control. The progress in stability has been in both the demonstration of devices maintaining at least 90% of the initial efficiency for over 19,000 hours of continuous light soak and the development of methods which can accurately predict long term behavior based on the first 5,000--10,000 hours of life. Experiments were conducted to determine if device behavior could be accelerated with thermal or voltage stresses. Notable achievements in deposition technology include depositing CdTe on a 3,600 cm{sup 2} substrate at 600 torr and designing and fabricating a new deposition feed system with a remote semiconductor source. The efficiency has been increased on small area devices to 13.3% by decreasing the thickness of the CdS and of the glass substrate. Work also focused on using a high resistivity SnO{sub 2} buffer layer between the TCO and thin CdS to help preserve the open-circuit voltage while increasing the current-density. The back contacting process has been simplified by replacing the wet post-deposition etch with a vapor Te deposition step on small area devices. Results show that the devices perform comparably in efficiency but better in stability under light-soaking and open-circuit conditions. Preliminary studies of the correlation between CdS photoluminescence after the chloride treatment and the final device efficiency have shown a positive correlation which may be applicable for in-line quality control. The final area of progress was through the successful demonstration of preventing at least 99.9% of all incoming Cd from leaving in an uncontrolled manner through the land, air or water.

Sasala, R.; Powell, R.; Dorer, G. [Solar Cells, Inc., Toledo, OH (United States)

1996-06-01T23:59:59.000Z

138

Some potential material supply constraints in solar systems for heating and cooling of buildings and process heat. (A preliminary screening to identify critical materials)  

DOE Green Energy (OSTI)

Nine Solar Heating and Cooling of Buildings (SHACOB) designs and three Agricultural and Industrial Process Heat (AIPH) designs have been studied to identify potential future material constraints to their large scale installation and use. The nine SHACOB and three AIPH systems were screened and found to be free of serious future material constraints. The screening was carried out for each individual system design assuming 500 million m/sup 2/ of collector area installed by the year 2000. Also, two mixed design scenarios, containing equal portions of each system design, were screened. To keep these scenarios in perspective, note that a billion m/sup 2/ containing a mixture of the nine SHACOB designs will yield an annual solar contribution of about 1.3 Quads or will displace about 4.2 Quads of fossil fuel used to generate electricity. For AIPH a billion square meters of the mixed designs will yield about 2.8 Quads/year. Three materials were identified that could possibly restrain the deployment of solar systems in the specific scenarios investigated. They are iron and steel, soda lime glass and polyvinyl fluoride. All three of these materials are bulk materials. No raw material supply constraints were found.

Watts, R.L.; Gurwell, W.E.; Nelson, T.A.; Smith, S.A.

1979-06-01T23:59:59.000Z

139

Reliable high-throughput FPGA interconnect using  

E-Print Network (OSTI)

Department, University of South Carolina Columbia, SC 29208, pollocpj@engr.sc.edu ABSTRACT Pipelines WITH EMBEDDED PIEZOELECTRIC WAFER ACTIVE SENSORS FOR CRITICAL PIPELINE HEALTH MONITORING. Lingyu Yu, PhD Mechanical Engineering Department, University of South Carolina Columbia, SC 29208, yu3@engr.sc.edu Victor

Lemieux, Guy

140

Available Technologies: Real Time High Throughput Isotopic ...  

Space exploration; Any scientific research involving the tracking of isotopic labels, as in: Solar power; Scintillators (deuterated, 10 B, 6 Li, 3 He) Batteries (doping)

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Constant Pressure High Throughput Membrane Permeation Testing...  

NLE Websites -- All DOE Office Websites (Extended Search)

plant flue gas or in natural gas sweetening, and the separation of methane from other biogas components. Membranes can be made from a vast array of organic or inorganic materials...

142

High-throughput (Combinatorial) "Foundry" for Inorganic ...  

Science Conference Proceedings (OSTI)

... heat into useful energy are desirable for applications such as automotive engine waste heat recovery, where their use improves fuel efficiency and ...

2013-07-01T23:59:59.000Z

143

A high-throughput distributed DNA  

E-Print Network (OSTI)

from de- lays of up to several seconds while memory is being reclaimed. We take the approach that one programming. In Proceedings of the 1992 IEEE International Confer- ence on Robotics and Automation. 7] Erann

Weller, Jennifer Walsh

144

Application of high throughput pretreatment and cohydrolysis...  

NLE Websites -- All DOE Office Websites (Extended Search)

et al., 2005), is recognized as a sustainable source of sugars that can be converted to biofuels and other biomaterials by a number of routes (Himmel et al., 2007). To produce...

145

Available Technologies: High Throughput Purification and ...  

APPLICATIONS OF TECHNOLOGY: Biomedical research, drug design; Biofuels; Biodecontamination; ADVANTAGES: More efficient than target affinity purification

146

High-throughput proteomics : optical approaches.  

SciTech Connect

Realistic cell models could greatly accelerate our ability to engineer biochemical pathways and the production of valuable organic products, which would be of great use in the development of biofuels, pharmaceuticals, and the crops for the next green revolution. However, this level of engineering will require a great deal more knowledge about the mechanisms of life than is currently available. In particular, we need to understand the interactome (which proteins interact) as it is situated in the three dimensional geometry of the cell (i.e., a situated interactome), and the regulation/dynamics of these interactions. Methods for optical proteomics have become available that allow the monitoring and even disruption/control of interacting proteins in living cells. Here, a range of these methods is reviewed with respect to their role in elucidating the interactome and the relevant spatial localizations. Development of these technologies and their integration into the core competencies of research organizations can position whole institutions and teams of researchers to lead in both the fundamental science and the engineering applications of cellular biology. That leadership could be particularly important with respect to problems of national urgency centered around security, biofuels, and healthcare.

Davidson, George S.

2008-09-01T23:59:59.000Z

147

High Throughput Single Molecule Investigation of Transcription  

E-Print Network (OSTI)

Binding Proteins. Angewandte Chemie International Edition,Binding Proteins. Angewandte Chemie International Edition,a methyltransferase. Angewandte Chemie 37, 2888-2891 (1998).

Kim, Soohong

2012-01-01T23:59:59.000Z

148

High-throughput and in situ EDXRD investigation on the formation of two new metal aminoethylphosphonates - Ca(O{sub 3}PC{sub 2}H{sub 4}NH{sub 2}) and Ca(OH)(O{sub 3}PC{sub 2}H{sub 4}NH{sub 3}){center_dot}2H{sub 2}O  

SciTech Connect

The system Ca{sup 2+}/2-aminoethylphosphonic acid/H{sub 2}O/NaOH was systematically investigated using high-throughput methods. The experiments led to one new compound Ca(O{sub 3}PC{sub 2} H{sub 4}NH{sub 2}) (1) and the crystal structure was determined using in house X-ray powder diffraction data (monoclinic, P2{sub 1}/c, a=9.7753(3), b=6.4931(2), c=8.4473(2) A, {beta}=106.46(2) Degree-Sign , V=514.20(2) A{sup 3}, Z=4). The formation of 1 was investigated by in situ energy dispersive X-ray diffraction measurements (EDXRD) at beamline F3 at HASYLAB (light source DORIS III), DESY, Hamburg. An intermediate, Ca(OH)(O{sub 3}PC{sub 2}H{sub 4}NH{sub 3}){center_dot}2H{sub 2}O (2), was observed and could be isolated from the reaction mixture at ambient temperatures by quenching the reaction. The crystal structure of 2 was determined from XRPD data using synchrotron radiation (monoclinic, P2{sub 1}/m, a=11.2193(7), b=7.1488(3), c=5.0635(2) A, {beta}=100.13(4) Degree-Sign , V=399.78(3) A{sup 3}, Z=2). - Graphical abstarct: The detailed in situ energy dispersive X-ray diffraction (EDXRD) investigation on the formation of the new inorganic-organic hybrid compound Ca(O{sub 3}PC{sub 2}H{sub 4}NH{sub 2}) leads to the discovery of a new crystalline intermediate phase. Both crystal structures were elucidated using X-ray powder diffraction data. Highlights: Black-Right-Pointing-Pointer High-throughput investigation led to new metal aminoethylphosphonate Ca(O{sub 3}PC{sub 2}H{sub 4}NH{sub 2}). Black-Right-Pointing-Pointer The formation of Ca(O{sub 3}PC{sub 2}H{sub 4}NH{sub 2}) was followed by in situ EDXRD measurements. Black-Right-Pointing-Pointer The crystalline intermediate Ca(O{sub 3}PC{sub 2}H{sub 4}NH{sub 3})(OH){center_dot}2H{sub 2}O was discovered. Black-Right-Pointing-Pointer Isolation of Ca(O{sub 3}PC{sub 2}H{sub 4}NH{sub 3})(OH){center_dot}2H{sub 2}O was accomplished by quenching experiments. Black-Right-Pointing-Pointer The structures were determined using X-ray powder diffraction data.

Schmidt, Corinna; Feyand, Mark [Institut fuer Anorganische Chemie, Christian-Albrechts-Universitaet, Max-Eyth Strasse 2, D 24118 Kiel (Germany); Rothkirch, Andre [HASYLAB, DESY Hamburg, Notkestrasse 85, 22607 Hamburg (Germany); Stock, Norbert, E-mail: stock@ac.uni-kiel.de [Institut fuer Anorganische Chemie, Christian-Albrechts-Universitaet, Max-Eyth Strasse 2, D 24118 Kiel (Germany)

2012-04-15T23:59:59.000Z

149

Shock waves in capillary collapse of colloids: a model system for two--dimensional screened Newtonian gravity  

E-Print Network (OSTI)

Using Brownian dynamics simulations, density functional theory, and analytical perturbation theory we study the collapse of a patch of interfacially trapped, micrometer-sized colloidal particles, driven by long-ranged capillary attraction. This attraction {is formally analogous} to two--dimensional (2D) screened Newtonian gravity with the capillary length \\hat{\\lambda} as the screening length. Whereas the limit \\hat{\\lambda} \\to \\infty corresponds to the global collapse of a self--gravitating fluid, for finite \\hat{\\lambda} we predict theoretically and observe in simulations a ringlike density peak at the outer rim of a disclike patch, moving as an inbound shock wave. Possible experimental realizations are discussed.

J. Bleibel; S. Dietrich; A. Dominguez; M. Oettel

2011-05-06T23:59:59.000Z

150

Recall the diagrams we saw before: Screen1Screen1  

E-Print Network (OSTI)

Customer EnterOrder customers orders buttons · When we trace through the diagram there are a number of keyX-machines · Recall the diagrams we saw before: Start Customers Orders Screen1Screen1 Screen2 Customers Screen Screen2 Customers Screen Screen3 Orders Screen Screen3 Orders Screen ClickCustomer Click

Holcombe, Mike

151

BCHP Screening Tool | Open Energy Information  

Open Energy Info (EERE)

BCHP Screening Tool BCHP Screening Tool Jump to: navigation, search Tool Summary LAUNCH TOOL Name: BCHP Screening Tool Agency/Company /Organization: Oak Ridge National Laboratory Sector: Energy Focus Area: Buildings, Industry Phase: Determine Baseline, Develop Goals Resource Type: Software/modeling tools, Guide/manual User Interface: Desktop Application Website: www.coolingheatingpower.org/about/bchp-screening-tool.php References: http://www.coolingheatingpower.org/about/bchp-screening-tool.php Logo: BCHP Screening Tool The BCHP Screening Tool is software that can be used to estimate the energy consumption and economics of CHP systems in commercial buildings. The BCHP Screening Tool is software that can be used to estimate the energy consumption and economics of CHP systems in commercial buildings. This tool

152

Latent Impingement Mortality Assessment of the Geiger Multi-DiscTM Screening System at the Potomac River Generating Station  

Science Conference Proceedings (OSTI)

This report presents the results of a field study evaluating the injury and survival of fish exposed to a Geiger Multi-Disc (Geiger) modified traveling water screen designed to protect juvenile and adult fish. The study was conducted at the Potomac River Generating Station owned by Mirant Potomac River, LLC. Information in this report provides the first performance database for this technology. Also, for the species tested, the data presented provide a basis on which to estimate the potential biological ...

2007-07-23T23:59:59.000Z

153

Toward loosely coupled programming on petascale systems  

Science Conference Proceedings (OSTI)

We have extended the Falkon lightweight task execution framework to make loosely coupled programming on petascale systems a practical and useful programming model. This work studies and measures the performance factors involved in applying this approach ... Keywords: Blue Gene, Falkon, Swift, high throughput computing, loosely coupled applications, many task computing, petascale

Ioan Raicu; Zhao Zhang; Mike Wilde; Ian Foster; Pete Beckman; Kamil Iskra; Ben Clifford

2008-11-01T23:59:59.000Z

154

Lectures on Screened Modified Gravity  

E-Print Network (OSTI)

The acceleration of the expansion of the Universe has led to the construction of Dark Energy models where a light scalar field may have a range reaching up to cosmological scales. Screening mechanisms allow these models to evade the tight gravitational tests in the solar system and the laboratory. I will briefly review some of the salient features of screened modified gravity models of the chameleon, dilaton or symmetron types using $f(R)$ gravity as a template.

Philippe Brax

2012-11-22T23:59:59.000Z

155

A system dynamics model for the screening-level long-term assessment of human health risks at contaminated sites  

Science Conference Proceedings (OSTI)

For the design of sustainable and cost-effective management strategies for contaminated sites, decision makers need appropriate tools, i.e. environmental decision support systems to assist them in the planning, assessment, selection and optimisation ... Keywords: Contaminated sites, EDSS, Human health risk assessment, Monitored natural attenuation, Risk-based land management, System dynamics, Uncertainty, Vensim

Ursula S. Mcknight; Michael Finkel

2013-02-01T23:59:59.000Z

156

An hourly-based performance comparison of an integrated micro-structural perforated shading screen with standard shading systems  

E-Print Network (OSTI)

protection with sun-shading systems, Solar Energy 69 (Suppl.total solar energy transmittance of the CFSs with sun pathbecause the sun altitude is also higher. The solar gains can

Appelfeld, David

2013-01-01T23:59:59.000Z

157

An hourly-based performance comparison of an integrated micro-structural perforated shading screen with standard shading systems  

E-Print Network (OSTI)

complex fenestration systems, Solar Energy, submitted foron prismatic glazing, Solar Energy 74 (2003) 157173. [13]of glazings and windows, Solar Energy 69 (Suppl. 16) (2000)

Appelfeld, David

2013-01-01T23:59:59.000Z

158

CLAD DEGRADATION - FEPS SCREENING ARGUMENTS  

Science Conference Proceedings (OSTI)

The purpose of this report is to evaluate and document the screening of the clad degradation features, events, and processes (FEPs) with respect to modeling used to support the Total System Performance Assessment-License Application (TSPA-LA). This report also addresses the effect of certain FEPs on both the cladding and the commercial spent nuclear fuel (CSNF), DOE-owned spent nuclear fuel (DSNF), and defense high-level waste (DHLW) waste forms, as appropriate to address the effects on multiple materials and both components (FEPs 2.1.09.09.0A, 2.1.09.11.0A, 2.1.11.05.0A, 2.1.12.02.0A, and 2.1.12.03.0A). These FEPs are expected to affect the repository performance during the postclosure regulatory period of 10,000 years after permanent closure. Table 1-1 provides the list of cladding FEPs, including their screening decisions (include or exclude). The primary purpose of this report is to identify and document the analysis, screening decision, and TSPA-LA disposition (for included FEPs) or screening argument (for excluded FEPs) for these FEPs related to clad degradation. In some cases, where a FEP covers multiple technical areas and is shared with other FEP reports, this report may provide only a partial technical basis for the screening of the FEP. The full technical basis for shared FEPs is addressed collectively by the sharing FEP reports. The screening decisions and associated TSPA-LA dispositions or screening arguments from all of the FEP reports are cataloged in a project-specific FEPs database.

R. Schreiner

2004-10-21T23:59:59.000Z

159

Cell rolling and adhesion on surfaces in shear flow. A model for an antibody-based microfluidic screening system  

Science Conference Proceedings (OSTI)

Here we present a model and an experimental investigation to study cell bound to the floor of a microfluidic system and the flow induced detachment. The experimental investigation has been performed by a microfluidic assay biofunctionalized with specific ... Keywords: Cell rolling, Microfluidic assay, Numerical model

G. Simone; G. Perozziello; E. Battista; F. De Angelis; P. Candeloro; F. Gentile; N. Malara; A. Manz; E. Carbone; P. Netti; E. Di Fabrizio

2012-10-01T23:59:59.000Z

160

Preliminary screening of thermal storage concepts for water/steam and organic fluid solar thermal receiver systems  

DOE Green Energy (OSTI)

A preliminary comparison of thermal storage concepts for solar thermal applications was done generically for large and small solar systems with sensible and latent heat and two-stage storage concepts. Concepts were ranked based on the cost of delivered energy. A +- 20% uncertainty in subsystem cost was included in the analysis. Water/steam and organic fluid collector/receivers were studied separately. For the water/steam concept, Barstow technology (100 MW/sub e/) was examined. A nitrite/nitrate salt with a low-cost solid medium was best for buffer storage; for diurnal storage, the two-stage draw salt/low-cost media and oil/rock concept was best. Phase change concepts require improvements on the concept analyzed to be attractive. For the organic fluid system, a Shenandoah total energy system was examined. The Syltherm trickle charge taconite concept was the most favorable and may be improved by replacing the taconite with a lower-cost oil-compatible medium. Salt concepts can be competitive with this system only if there is a low-cost solid medium that is compatible with the salt and the end use requires a large amount of storage. The phase change concept examined was found to be quite poor for this total energy application.

Copeland, R.J.; Karpuk, M.E.; Ullman, J.L.

1980-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Screening study for evaluation of the potential for system 80+ to consume excess plutonium - Volume 2. Final report  

Science Conference Proceedings (OSTI)

As part of the U.S. effort to evaluate technologies offering solutions for the safe disposal or utilization of surplus nuclear materials, the fiscal year 1993 Energy and Water Appropriations legislation provided the Department of Energy (DOE) the necessary funds to conduct multi-phased studies to determine the technical feasibility of using reactor technologies for the triple mission of burning weapons grade plutonium, producing tritium for the existing smaller weapons stockpile, and generating commercial electricity. DOE limited the studies to five advanced reactor designs. Among the technologies selected is the ABB-Combustion Engineering (ABB-CE) System 80+. The DOE study, currently in Phase ID, is proceeding with a more detailed evaluation of the design`s capability for plutonium disposition.

Not Available

1994-04-30T23:59:59.000Z

162

Biomarkers of acute respiratory allergen exposure: Screening for sensitization potential  

Science Conference Proceedings (OSTI)

Effective hazard screening will require the development of high-throughput or in vitro assays for the identification of potential sensitizers. The goal of this preliminary study was to identify potential biomarkers that differentiate the response to allergens vs non-allergens following an acute exposure in naive individuals. Female BALB/c mice received a single intratracheal aspiration exposure to Metarhizium anisopliae crude antigen (MACA) or bovine serum albumin (BSA) in Hank's Balanced Salt Solution (HBSS) or HBSS alone. Mice were terminated after 1, 3, 6, 12, 18 and 24 h. Bronchoalveolar lavage fluid (BALF) was evaluated to determine total and differential cellularity, total protein concentration and LDH activity. RNA was isolated from lung tissue for microarray analysis and qRT-PCR. MACA administration induced a rapid increase in BALF neutrophils, lymphocytes, eosinophils and total protein compared to BSA or HBSS. Microarray analysis demonstrated differential expression of genes involved in cytokine production, signaling, inflammatory cell recruitment, adhesion and activation in 3 and 12 h MACA-treated samples compared to BSA or HBSS. Further analyses allowed identification of approx 100 candidate biomarker genes. Eleven genes were selected for further assessment by qRT-PCR. Of these, 6 demonstrated persistently increased expression (Ccl17, Ccl22, Ccl7, Cxcl10, Cxcl2, Saa1), while C3ar1 increased from 6-24 h. In conclusion, a single respiratory exposure of mice to an allergenic mold extract induces an inflammatory response which is distinct in phenotype and gene transcription from the response to a control protein. Further validation of these biomarkers with additional allergens and irritants is needed. These biomarkers may facilitate improvements in screening methods.

Pucheu-Haston, Cherie M., E-mail: Pucheu-Haston.Cherie@epa.go [Curriculum in Toxicology, University of North Carolina-Chapel Hill, CB 7270, Chapel Hill, NC 27599-7270 (United States); Copeland, Lisa B.; Vallanat, Beena; Boykin, Elizabeth; Ward, Marsha D.W. [National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711 (United States)

2010-04-15T23:59:59.000Z

163

Screening | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Screening Screening Screening October 16, 2013 - 5:17pm Addthis Screening is typically performed by an outside party or an independent renewable energy expert or team. It is a review of the possible technology options that identifies dead-ends and further narrows the list to probable technologies for the project. A screening provides a preliminary assessment of how much energy could be produced by various renewable energy technologies and conducts a high-level analysis of expected costs and savings, utility considerations, and potential incentives. Federal agencies can analyze specific sites or conduct an agency-wide screening across properties to decide which areas have the greatest renewable energy potential. When conducted in conjunction with a new construction project or major renovation, an agency should get results from

164

Rapid Isotopic Screening  

Science Conference Proceedings (OSTI)

... Cameca IMS-1270 is a high sensitivity large ... the capability to screen the enrichment levels of ... a test run of 100 particles of highly enriched uranium. ...

2012-10-02T23:59:59.000Z

165

Medical Screening Former Worker Medical Screening Program (FWP)  

Energy.gov (U.S. Department of Energy (DOE))

Medical Screening: Provide medical screening exams that are designed to check for health conditions related to occupational exposures to former workers who choose to participate in the program, including a re-screen exam every three years.

166

Catalyst Screening and Kinetic Studies Using Microchannel Reactors  

SciTech Connect

A multi-parallel microchannel reactor system is described, as related to catalyst screening and discovery for heat-intensive heterogeneous catalytic reactions. Example systems are detailed, in which the rapid heat transfer of the screening device is utilized to maintain isothermal operation in multiple channels for catalyst screening as well as kinetic investigations. The advantages of the system and pertinent results are discussed, specifically for Fischer-Tropsch synthesis, methanol oxidation to formaldehyde, and methanol steam reforming.

Cao, Chunshe; Palo, Daniel R.; Tonkovich, Annalee Y.; Wang, Yong

2007-07-15T23:59:59.000Z

167

Pinellas, Former Production Workers Screening Projects | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Pinellas, Former Production Workers Screening Projects Pinellas, Former Production Workers Screening Projects Project Name: National Supplemental Screening Program Covered DOE...

168

Clad Degradation - FEPs Screening Arguments  

Science Conference Proceedings (OSTI)

The purpose of this report is to document the screening of the cladding degradation features, events, and processes (FEPs) for commercial spent nuclear fuel (CSNF). This report also addresses the effect of some FEPs on both the cladding and the CSNF, DSNF, and HLW waste forms where it was considered appropriate to address the effects on both materials together. This report summarizes the work of others to screen clad degradation FEPs in a manner consistent with, and used in, the Total System Performance Assessment-License Application (TSPA-LA). This document was prepared according to ''Technical Work Plan for Waste Form Degradation Modeling, Testing, and Analyses in Support of LA'' (BSC 2004a [DIRS 167796]).

E. Siegmann

2004-03-17T23:59:59.000Z

169

Algorithm for Screening Phasor Measurement Unit Data for Power System Events and Categories and Common Characteristics for Events Seen in Phasor Measurement Unit Relative Phase-Angle Differences and Frequency Signals  

SciTech Connect

A network of multiple phasor measurement units (PMU) was created, set up, and maintained at the University of Texas at Austin to obtain actual power system measurements for power system analysis. Power system analysis in this report covers a variety of time ranges, such as short- term analysis for power system disturbances and their effects on power system behavior and long- term power system behavior using modal analysis. The first objective of this report is to screen the PMU data for events. The second objective of the report is to identify and describe common characteristics extracted from power system events as measured by PMUs. The numerical characteristics for each category and how these characteristics are used to create selection rules for the algorithm are also described. Trends in PMU data related to different levels and fluctuations in wind power output are also examined.

Allen, A.; Santoso, S.; Muljadi, E.

2013-08-01T23:59:59.000Z

170

Assimilation of Screen-Level Variables in ECMWFs Integrated Forecast System: A Study on the Impact on the Forecast Quality and Analyzed Soil Moisture  

Science Conference Proceedings (OSTI)

In many operational numerical weather prediction applications, the soil moisture analysis is based on the modeled first-guess and screen-level variables; that is, 2-m temperature and 2-m relative humidity. A set of two global 61-day analysis/...

Matthias Drusch; Pedro Viterbo

2007-02-01T23:59:59.000Z

171

Technology support for initiation of high-throughput processing of thin-film CdTe PV modules. Phase 3 final technical report, 14 March 1997--1 April 1998  

SciTech Connect

Thin-film PV devices based on cadmium telluride have been identified as one of the candidates for high-performance, low-cost source of renewable electrical energy. Roadblocks to their becoming a part of the booming PV market growth have been a low rate of production and high manufacturing cost caused by several rate-limiting process steps. Solar Cells Inc. has focused on the development of manufacturing processes that will lead to high volume and low-cost manufacturing of solar cells and on increasing the performance of the present product. The process research in Phase 3 was concentrated on further refinement of a newly developed vapor transport deposition (VTD) process and its implementation into the manufacturing line. This development included subsystems for glass substrate transport, continuous feed of source materials, generation of source vapors, and uniform deposition of the semiconductor layers. As a result of this R and D effort, the VTD process has now achieved a status in which linear coating speeds in excess of 8 ft/min have been achieved for the semiconductor, equal to about two modules per minute, or 144 kW per 24 hour day. The process has been implemented in a production line, which is capable of round-the-clock continuous production of coated substrates 120 cm x 60 cm in size at a rate of 1 module every four minutes, equal to 18 kW/day. Currently the system cycle time is limited by the rate of glass introduction into the system and glass heating, but not by the rate of the semiconductor deposition. A new SCI record efficiency of 14.1% has been achieved for the cells.

Powell, R.C.; Dorer, G.L.; Jayamaha, U.; Hanak, J.J. [Solar Cells, Inc., Toledo, OH (United States)

1998-09-01T23:59:59.000Z

172

Screening Risk Evaluation methodology  

Science Conference Proceedings (OSTI)

The Screening Risk Evaluation (SRE) Guidance document is a set of guidelines provided for the uniform implementation of SREs performed on D&D facilities. These guidelines are designed specifically for the completion of the second (semi-quantitative screening) phase of the D&D Risk-Based Process. The SRE Guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the risk to human health and the environment from ongoing or probable releases within a one year time period. The Worker Exposure Index (WEI) calculates the risk to workers, occupants, and visitors in D&D facilities of contaminant exposure. The Future Release Index (FRI) calculates the risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risk-to human health due to factors other than that of contaminants. The index of Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, determined on a project by project basis. The SRE is the first and most important step in the overall D&D project level decision making process.

Hopper, K.M. [Midwest Technical, Inc., Oak Ridge, TN (United States)

1994-06-01T23:59:59.000Z

173

Preliminary Screening Analysis for the Environmental Risk Evaluation System: Task 2.1.1: Evaluating Effects of Stressors Fiscal Year 2010 Progress Report: Environmental Effects of Marine and Hydrokinetic Energy  

Science Conference Proceedings (OSTI)

Possible environmental effects of marine and hydrokinetic (MHK) energy development are not well understood, and yet regulatory agencies are required to make decisions in spite of substantial uncertainty about environmental impacts and their long-term effects. An understanding of risk associated with likely interactions between MHK installations and aquatic receptors, including animals, habitats, and ecosystems, can help reduce the level of uncertainty and focus regulatory actions and scientific studies on interactions of most concern. As a first step in developing the Pacific Northwest National Laboratory (PNNL) Environmental Risk Evaluation System (ERES), PNNL scientists conducted a preliminary risk screening analysis on three initial MHK cases - a tidal project in Puget Sound using Open Hydro turbines, a wave project off the coast of Oregon using Ocean Power Technologies point attenuator buoys, and a riverine current project in the Mississippi River using Free Flow turbines. Through an iterative process, the screening analysis revealed that top-tier stressors in all three cases were the effects of the dynamic physical presence of the device (e.g., strike), accidents, and effects of the static physical presence of the device (e.g., habitat alteration). Receptor interactions with these stressors at the four highest tiers of risk were dominated by marine mammals (cetaceans and pinnipeds) and birds (diving and non-diving); only the riverine case (Free Flow) included different receptors in the third tier (fish) and the fourth tier (benthic invertebrates). Although this screening analysis provides a preliminary analysis of vulnerability of environmental receptors to stressors associated with MHK installations, probability analysis, especially of risk associated with chemical toxicity and accidents such as oil spills or lost gear, will be necessary to further understand high-priority risks. Subject matter expert review of this process and results is required and is planned for the first quarter of FY11. Once expert review is finalized, the screening analysis phase of ERES will be complete.

Anderson, Richard M.; Copping, Andrea E.; Van Cleve, Frances B.

2010-11-15T23:59:59.000Z

174

A model for the evaluation of fault tolerance in the FERMI system  

Science Conference Proceedings (OSTI)

Experiments of high energy physics planned at the Large Hadron Collider (LHC) at CERN (CH) require digital data acquisition systems with high throughput. Such systems need also be fault tolerant to the permanent and transient faults induced by radiation, ... Keywords: FERMI microsystem, Large Hadron Collider, VLSI, VLSI devices, data acquisition, digital data acquisition system, fault tolerance, fault tolerant computing, high energy physics, high energy physics instrumentation computing, model, nuclear electronics, radiation effects

A. Antola; L. Breveglieri

1995-11-01T23:59:59.000Z

175

Screening Analysis : Volume 1, Description and Conclusions.  

DOE Green Energy (OSTI)

The SOR consists of three analytical phases leading to a Draft EIS. The first phase Pilot Analysis, was performed for the purpose of testing the decision analysis methodology being used in the SOR. The Pilot Analysis is described later in this chapter. The second phase, Screening Analysis, examines all possible operating alternatives using a simplified analytical approach. It is described in detail in this and the next chapter. This document also presents the results of screening. The final phase, Full-Scale Analysis, will be documented in the Draft EIS and is intended to evaluate comprehensively the few, best alternatives arising from the screening analysis. The purpose of screening is to analyze a wide variety of differing ways of operating the Columbia River system to test the reaction of the system to change. The many alternatives considered reflect the range of needs and requirements of the various river users and interests in the Columbia River Basin. While some of the alternatives might be viewed as extreme, the information gained from the analysis is useful in highlighting issues and conflicts in meeting operating objectives. Screening is also intended to develop a broad technical basis for evaluation including regional experts and to begin developing an evaluation capability for each river use that will support full-scale analysis. Finally, screening provides a logical method for examining all possible options and reaching a decision on a few alternatives worthy of full-scale analysis. An organizational structure was developed and staffed to manage and execute the SOR, specifically during the screening phase and the upcoming full-scale analysis phase. The organization involves ten technical work groups, each representing a particular river use. Several other groups exist to oversee or support the efforts of the work groups.

Bonneville Power Administration; Corps of Engineers; Bureau of Reclamation

1992-08-01T23:59:59.000Z

176

Algorithms for high-throughput disk-to-disk sorting  

Science Conference Proceedings (OSTI)

In this paper, we present a new out-of-core sort algorithm, designed for problems that are too large to fit into the aggregate RAM available on modern supercomputers. We analyze the performance including the cost of IO and demonstrate the fastest (to ... Keywords: asynchronous methods, distributed-memory parallelism, hypercube, out-of-core algorithms, parallel algorithms, quicksort, samplesort, shared-memory parallelism, sorting

Hari Sundar, Dhairya Malhotra, Karl W. Schulz

2013-11-01T23:59:59.000Z

177

High-throughput sequencing of cytosine methylation in plant DNA  

E-Print Network (OSTI)

to that in flowering plants around repeat regions [15]. The green algae Chlorella sp. NC64A and Volvox carteri show very little methylation in non-CpG contexts in genes, and greatly reduced or absent non-CpG methylation at repetitive regions, with Volvox carteri... showing greatly reduced methylation in all contexts compared to other plant species [15]. Similarly, the distributions of methyla- tion in the green algae Chlamydomonas, while not wholly divergent from those in flowering plants [49], show much lower levels...

Hardcastle, Thomas J

2013-06-07T23:59:59.000Z

178

High-throughput Synthesis and Metrology of Graphene Materials  

E-Print Network (OSTI)

24 2.5 Demonstration of PGN based Supercapacitor2-11 (a) CV curves of supercapacitor based on as-grown PGNFigure 2-12 CV curves of supercapacitor based on HNO3 acid

Ghazinejad, Maziar Ghazinejad

2012-01-01T23:59:59.000Z

179

High-Throughput Dry Processes for Large-Area Devices  

DOE Green Energy (OSTI)

In October 1996, an interdisciplinary team began a three-year LDRD project to study the plasma processes of reactive ion etching and plasma-enhanced chemical vapor deposition on large-area silicon devices. The goal was to develop numerical models that could be used in a variety of applications for surface cleaning, selective etching, and thin-film deposition. Silicon solar cells were chosen as the experimental vehicle for this project because an innovative device design was identified that would benefit from immediate performance improvement using a combination of plasma etching and deposition processes. This report presents a summary of the technical accomplishments and conclusions of the team.

BUSS,RICHARD J.; HEBNER,GREGORY A.; RUBY,DOUGLAS S.; YANG,PIN

1999-11-01T23:59:59.000Z

180

Algorithms for Next-Generation High-Throughput Sequencing Technologies  

E-Print Network (OSTI)

Batzoglou, Whole- genome sequencing and assembly with high-this promise of whole genome sequencing to fruition, severalcerevisiae whole-genome sequencing dataset, we discover that

Kao, Wei-Chun

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Microchip Technology for High-Throughput Cancer Pathology  

E-Print Network (OSTI)

Sequencing in Cancer Research . . . . 80 Appendix A: High-the Warburg Effect. Cancer Research, 2006. 66(18): p. 8927-Breast Cancer Risk. Cancer Research, 2007. 67(10): p. 4687-

Duberow, Jr, David Paul

2009-01-01T23:59:59.000Z

182

Low inlet gas velocity high throughput biomass gasifier  

DOE Patents (OSTI)

The present invention discloses a novel method of operating a gasifier for production of fuel gas from carbonaceous fuels. The process disclosed enables operating in an entrained mode using inlet gas velocities of less than 7 feet per second, feedstock throughputs exceeding 4000 lbs/ft.sup.2 -hr, and pressures below 100 psia.

Feldmann, Herman F. (Worthington, OH); Paisley, Mark A. (Upper Arlington, OH)

1989-01-01T23:59:59.000Z

183

Leveraging high-throughput datasets for studies of gene regulation  

E-Print Network (OSTI)

In this thesis, I leveraged computational methods on biological data to better understand gene regulation and development of the human body, as well as of the model organisms mouse and yeast. Firstly, I tackled biological ...

Yen, Angela

2011-01-01T23:59:59.000Z

184

High-Throughput Nanofabrication of Infrared Plasmonic Nanoantenna Arrays for  

E-Print Network (OSTI)

are used with calcium fluoride and barium fluoride filters to separate the atomic oxygen 130.4 nm line from A has a calcium fluoride (CaF2) filter placed in front of the detector and channel B has a barium. The hardware, software and procedures used for ground testing will be re-used during on-orbit operations

185

Operational streamlining in a high-throughput genome sequencing center  

E-Print Network (OSTI)

Advances in medicine rely on accurate data that is rapidly provided. It is therefore critical for the Genome Sequencing platform of the Broad Institute of MIT and Harvard to continually strive to reduce cost, improve ...

Person, Kerry P. (Kerry Patrick)

2006-01-01T23:59:59.000Z

186

Improved Algae-based Biorefining and High-throughput Vaccine ...  

measurements, in conjunction with photosynthesis and lipid assays. Vaccine for Prevention and Treatment of Autoimmune Diseases Page 1 of 1 IP Status: Available for

187

Computational Methods for Learning Bayesian Networks from High-Throughput  

E-Print Network (OSTI)

of the analysis thus far has focused on identifying differential measurements, which form the basis of biomarker being measured. The holy grail of such techniques is the robust identification of causal models measurements of cellular activity. Specifically, we will sur- vey computational methods for learning Bayesian

Subramanian, Devika

188

Microchip Technology for High-Throughput Cancer Pathology  

E-Print Network (OSTI)

ribosomal RNA RTD . . . . . . . . . . . . . . . . . . . . .temperature detectors (RTDs) patterned directly onto the

Duberow, Jr, David Paul

2009-01-01T23:59:59.000Z

189

High Throughput Quantification of Grain Boundary Segregation by ...  

Science Conference Proceedings (OSTI)

... by Correlative Transmission Electron Microscopy and Atom Probe Tomography ... Line Tension of Grain Boundary Triple Junctions in the Copper Tricrystals.

190

High-?Throughput and Ab IniYo Molecular Dynamics ...  

Science Conference Proceedings (OSTI)

... Addigon of phonons for a empt frequencies, thermal expansion (See Chelsea Zacherl talk for efficient ... vacancy requires the handling of two extra ...

2012-10-01T23:59:59.000Z

191

Integrated microbioreactor arrays for high-throughput experimentation  

E-Print Network (OSTI)

Bioprocesses with microbial cells play an important role in producing biopharmaceuticals such as human insulin and human growth hormone, and other products such as amino acids and biopolymers. Because bioprocesses involve ...

Lee, Harry, 1976-

2006-01-01T23:59:59.000Z

192

Former Worker Medical Screening Program  

Energy.gov (U.S. Department of Energy (DOE))

The Former Worker Medical Screening Program (FWP) provides ongoing medical screening examinations, at no cost, to all former DOE Federal, contractor, and subcontractor workers who may be at risk for occupational diseases.

193

X-ray Security Screening  

Science Conference Proceedings (OSTI)

National and International Standards for X-ray Security Screening Applications. Summary: The primary objective of this ...

2013-03-13T23:59:59.000Z

194

Scientific Analysis Cover Sheet for Radionuclide Screening  

Science Conference Proceedings (OSTI)

The waste forms under consideration for disposal in the proposed repository at Yucca Mountain contain scores of radionuclides (Attachments V and VI). It would be impractical and highly inefficient to model all of these radionuclides in a total system performance assessment (TSPA). Thus, the purpose of this radionuclide screening analysis is to remove from further consideration (screen out) radionuclides that are unlikely to significantly contribute to radiation dose to the public from the proposed nuclear waste repository at Yucca Mountain. The remaining nuclides (those screened in) are recommended for consideration in TSPA modeling for license application. This analysis also covers radionuclides that are not screened in based on dose, but need to be included in TSPA modeling for other reasons. For example, U.S. Environmental Protection Agency (EPA) and U.S. Nuclear Regulatory Commission (NRC) regulations require consideration of the combined activity of Ra-226 and Ra-228 in groundwater (40 CFR 197.30, 10 CFR 63.331). Also, Cm-245, Pu-241, and U-235 decay indirectly to potentially important radionuclides, and are not identified by the screening analysis as important. The radionuclide screening analysis separately considers two different postclosure time periods: the 10,000-y regulatory period for the proposed repository at Yucca Mountain and the period after 10,000 y up to 1 million y after emplacement. The incremental effect of extending the screening for the regulatory period to 20,000 y is also addressed. Four release scenarios are considered: (1) the nominal scenario, which entails long-term degradation of disposal containers and waste forms, (2) a human-intrusion scenario, (3) an intrusive igneous event, and (4) an eruptive igneous event. Because the first three scenarios require groundwater transport, they are called groundwater scenarios below. The screening analysis considers the following waste forms: spent boiling water reactor (BWR) fuel, spent pressurized water reactor (PWR) fuel, U.S. Department of Energy (DOE) spent nuclear fuel (DSNF), and high-level waste (HLW). Average and outlying (high burnup, high initial enrichment, low age, or otherwise exceptional) forms of each waste-form type are considered. This analysis has been prepared in accordance with a technical work plan (BSC 2002c). In a review of Revision 00 of this radionuclide screening analysis, the NRC found that ''processes that affect transport in the biosphere, such as uptake by plants and bioaccumulation are not accounted for'' and that ''the direct exposure pathway is not accounted for'' (Beckman 2001, Section 5.3.2.1). The NRC also found that the solubility and sorption classes were too broadly defined, noting, for example, that Se is in the same solubility and sorptivity groups as Np and U, yet is ''more soluble than Np and U by several orders of magnitude'' (Beckman 2001, Section 5.3.2.1). This revision seeks to build upon the strengths of the earlier screening method while responding to the specific concerns raised by the NRC and other reviewers. In place of simple inhalation and ingestion dose conversion factors, the revised radionuclide screening uses screening factors that also take into account soil accumulation, uptake by plants, exposure to contaminated ground, and other features of the biosphere that were neglected in the previous screening. Whereas the previous screening analysis allowed only two solubility classes (soluble and insoluble), the revised screening introduces an intermediate solubility class to better segregate the radionuclides into transport groups.

G. Ragan

2002-08-09T23:59:59.000Z

195

National Supplemental Screening Program | Argonne National Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

National Supplemental Screening Program The National Supplemental Screening Program (NSSP) offers medical screenings at no charge for former U.S. Department of Energy (DOE) site...

196

Hanford, Former Production Workers Screening Projects | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Hanford, Former Production Workers Screening Projects Hanford, Former Production Workers Screening Projects Project Name: National Supplemental Screening Program Covered DOE Site:...

197

GPU Computational Screening  

NLE Websites -- All DOE Office Websites (Extended Search)

GPU GPU Computational Screening of Carbon Capture Materials J. Kim 1 , A Koniges 1 , R. Martin 1 , M. Haranczyk 1 , J. Swisher 2 , and B. Smit 1,2 1 Lawrence Berkeley National Laboratory, Berkeley, CA 94720 2 Department of Chemical Engineering, University of California, Berkeley, Berkeley, CA 94720 E-mail: jihankim@lbl.gov Abstract. In order to reduce the current costs associated with carbon capture technologies, novel materials such as zeolites and metal-organic frameworks that are based on microporous networks are being studied. We have developed a GPU code that can characterize and screen a large database of zeolite structures and help identify the most e cient structures for carbon capture. The interactions between the atoms that constitute the zeolite structures and the gas molecules such as carbon dioxide and methane are described by the Lennard-Jones and Coulomb potentials.

198

John Day Fish Passage and Screening; 2001 Annual Report.  

Science Conference Proceedings (OSTI)

The accomplishments of the John Day, Umatilla, and Walla Walla Fish Passage and Screening Programs include the following: Operation and maintenance of 364 existing fish screening devices (see Table 4), replacement of 18 outdated fish screening devices that totaled 31 rotary drums (some were multiple drum systems), 4 new screens at unscreened diversions, 26 pump intake fish screens, fabrication of components for 16 additional fish screens for the Rogue basin, construction of two fish passage structures, and participation in other activities. After the replacement or construction of 22 fish screening devices during 2001, we now have 108 screening devices that meet NMFS criteria. Funding for these projects was attained from BPA, NMFS and OWEB. The John Day Fish Passage and Screening Program focused construction efforts into new and replacement fish screening devices for these various programs throughout the state of Oregon. The program also continued to develop and implement innovative designs to meet the diverse and expanding needs for the state of Oregon. Projects completed during this report period meet the current National Marine Fisheries Service (NMFS) criteria. Fish species targeted for protection include ESA Listed Mid-Columbia steelhead, Columbia basin bull trout, anadromous and resident salmonids, and numerous non-game fish species. Priority project locations have been identified as the upper reaches of the Middle Fork, North Fork, South Fork and the Mainstem of the John Day River and their tributaries. These upper reaches contain critical salmon and steelhead spawning and rearing habitat.

Allen, Steve (Oregon Department of Fish and Wildlife, John Day, OR)

2002-03-26T23:59:59.000Z

199

Glossary of Screen Labels for PARS II V1  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Glossary 1 Glossary 1 Glossary of Screen Labels for PARS II V1.0.0 Goal The primary goal of this glossary is to help PARS II end users understand the items of data that they are viewing or entering on their PARS II application screens. It does not provide technical information on the schema of the PARS II database. A separate PARS II Data Dictionary document is being provided for PARS II users who need such technical information. Overview This document consists of a table defining each data label displayed on PARS II screens. It is divided into sections by PARS II screen title. To find the meaning of a data item, first find the section describing the relevant screen, then find the particular screen label description. The sections are listed in order of the major functional area of the PARS II System:

200

Natural convection in a vertical enclosure with internal permeable screen  

SciTech Connect

This paper documents the thermal insulation effect of a screen installed inside a vertical rectangular enclosure (e.g., double-glazed window). The screen is a venetian blind system made out of horizontal strips that can be rotated. The focus is on the closed position, where the strips almost touch. The effect of this permeable screen on the temperature field, the flow field, and the overall heat transfer rate is determined numerically. The study shows that there exists a ceiling (critical) conductance for the air leakage through the screen, above which the screen does not cause a significant drop in the overall heat transfer rate. A numerical example shows how this critical conductance can be used to calculate the critical spacing that can be tolerated between two consecutive strips in the screen.

Zhang, Z.; Bejan, A.; Lage, J.L. (Duke Univ., Durham, NC (USA))

1991-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Medical Screening | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Program Program Implementation » Medical Screening Medical Screening Medical Screening: Provide medical screening exams that are designed to check for health conditions related to occupational exposures to former workers who choose to participate in the program, including a re-screen exam every three years. Conventional Medical Screening Program Medical screening is a strategy used to identify diseases or conditions in a select population at an early stage, often before signs and symptoms develop, and to refer individuals with suspicious findings to their personal physician or a specialist for further testing, diagnosis, and treatment. The program is not intended to serve as a substitute for routine medical exams through an individual's personal physician. Early Lung Cancer Detection Program

202

DYNAMIC SCREENING IN SOLAR PLASMA  

Science Conference Proceedings (OSTI)

In the hot, dense plasma of solar and stellar interiors, Coulomb potentials are screened, resulting in increased nuclear reaction rates. Although Salpeter's approximation for static screening is widely accepted and used in stellar modeling, the question of screening in nuclear reactions has been revisited. In particular, the issue of dynamic effects has been raised by Shaviv and Shaviv who apply the techniques of molecular dynamics to the conditions in the Sun's core in order to numerically determine the effect of screening. By directly calculating the motion of ions and electrons due to Coulomb interactions, the simulations are used to compute the effect of screening without the mean field assumption inherent in Salpeter's approximation. In this paper, we reproduce their numerical analysis of the screening energy in the plasma of the solar core and conclude that the effects of dynamic screening are relevant and should be included when stellar nuclear reaction rates are computed.

Mao, Dan; Daeppen, Werner [Department of Physics and Astronomy, University of Southern California, Los Angeles, CA 90089 (United States); Mussack, Katie [Institute of Astronomy, University of Cambridge, Cambridge CB3 0HA (United Kingdom)], E-mail: mussack@ast.cam.ac.uk

2009-08-20T23:59:59.000Z

203

Dynamic screening in solar plasma  

E-Print Network (OSTI)

In the hot, dense plasma of solar and stellar interiors, Coulomb potentials are screened, resulting in increased nuclear reaction rates. Although Salpeter's approximation for static screening is widely accepted and used in stellar modeling, the question of screening in nuclear reactions has been revisited. In particular the issue of dynamic effects has been raised by Shaviv and Shaviv who apply the techniques of molecular dynamics to the conditions in the Sun's core in order to numerically determine the effect of screening. By directly calculating the motion of ions and electrons due to Coulomb interactions, the simulations are used to compute the effect of screening without the mean-field assumption inherent in Salpeter's approximation. In this paper we reproduce their numerical analysis of the screening energy in the plasma of the solar core and conclude that the effects of dynamic screening are relevant and should be included when stellar nuclear reaction rates are computed.

Mao, Dan; Dppen, Werner

2009-01-01T23:59:59.000Z

204

Mallinckrodt Chemical Co., Former Construction Worker Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Mallinckrodt Chemical Co., Former Construction Worker Screening Projects Mallinckrodt Chemical Co., Former Construction Worker Screening Projects Project Name: Building Trades...

205

Screening Analysis for the Environmental Risk Evaluation System Task 2.1.1.2: Evaluating Effects of Stressors Fiscal Year 2011 Progress Report - Environmental Effects of Marine and Hydrokinetic Energy  

SciTech Connect

Potential environmental effects of marine and hydrokinetic (MHK) energy development are not well understood, and yet regulatory agencies are required to make decisions in spite of substantial uncertainty about environmental impacts and their long-term consequences. An understanding of risks associated with interactions between MHK installations and aquatic receptors, including animals, habitats, and ecosystems, can help define key uncertainties and focus regulatory actions and scientific studies on interactions of most concern. As a first step in developing the Pacific Northwest National Laboratory (PNNL) Environmental Risk Evaluation System (ERES), PNNL scientists conducted a preliminary risk screening analysis on three initial MHK cases. During FY 2011, two additional cases were added: a tidal project in the Gulf of Maine using Ocean Renewable Power Company TidGenTM turbines and a wave project planned for the coast of Oregon using Aquamarine Oyster surge devices. Through an iterative process, the screening analysis revealed that top-tier stressors in the two FY 2011 cases were the dynamic effects of the device (e.g., strike), accidents/disasters, and effects of the static physical presence of the device (e.g., habitat alteration). Receptor interactions with these stressors at the highest tiers of risk were dominated by threatened and endangered animals. Risk to the physical environment from changes in flow regime also ranked high. Peer review of this process and results will be conducted in early FY 2012. The ERES screening analysis provides an analysis of vulnerability of environmental receptors to stressors associated with MHK installations, probability analysis is needed to determine specific risk levels to receptors. Risk has two components: (1) The likelihood, or probability, of the occurrence of a given interaction or event, and (2) the potential consequence if that interaction or event were to occur. During FY 2011, the ERES screening analysis focused primarily on the second component of risk, consequence, with focused probability analysis for interactions where data was sufficient for probability modeling. Consequence analysis provides an assessment of vulnerability of environmental receptors to stressors associated with MHK installations. Probability analysis is needed to determine specific risk levels to receptors and requires significant data inputs to drive risk models. During FY 2011, two stressor-receptor interactions were examined for the probability of occurrence. The two interactions (spill probability due to an encounter between a surface vessel and an MHK device; and toxicity from anti-biofouling paints on MHK devices) were seen to present relatively low risks to marine and freshwater receptors of greatest concern in siting and permitting MHK devices. A third probability analysis was scoped and initial steps taken to understand the risk of encounter between marine animals and rotating turbine blades. This analysis will be completed in FY 2012.

Copping, Andrea E.; Blake, Kara M.; Anderson, Richard M.; Zdanski, Laura C.; Gill, Gary A.; Ward, Jeffrey A.

2011-09-01T23:59:59.000Z

206

Updating Technical Screens for PV Interconnection: Preprint  

DOE Green Energy (OSTI)

Solar photovoltaics (PV) is the dominant type of distributed generation (DG) technology interconnected to electric distribution systems in the United States, and deployment of PV systems continues to increase rapidly. Considering the rapid growth and widespread deployment of PV systems in United States electric distribution grids, it is important that interconnection procedures be as streamlined as possible to avoid unnecessary interconnection studies, costs, and delays. Because many PV interconnection applications involve high penetration scenarios, the process needs to allow for a sufficiently rigorous technical evaluation to identify and address possible system impacts. Existing interconnection procedures are designed to balance the need for efficiency and technical rigor for all DG. However, there is an implicit expectation that those procedures will be updated over time in order to remain relevant with respect to evolving standards, technology, and practical experience. Modifications to interconnection screens and procedures must focus on maintaining or improving safety and reliability, as well as accurately allocating costs and improving expediency of the interconnection process. This paper evaluates the origins and usefulness of the capacity penetration screen, offers potential short-term solutions which could effectively allow fast-track interconnection to many PV system applications, and considers longer-term solutions for increasing PV deployment levels in a safe and reliable manner while reducing or eliminating the emphasis on the penetration screen.

Coddington, M.; Ellis, A.; Lynn, K.; Razon, A.; Key, T.; Kroposki, B.; Mather, B.; Hill, R.; Nicole, K.; Smith, J.

2012-08-01T23:59:59.000Z

207

9:20 5 Novel Approaches to Increasing Selectivity, Peak Capacity, and Resolution in Chromatographic and  

E-Print Network (OSTI)

9:50 6 High-Throughput Electrophoresis and Application to Screening, Protein Analysis, and In-Vivo Sensing,

Chemometrics For Process Underst; Romtauler Idaea-csic; Honoring Prof; Luis A. Coln; Suny Buffalo; Electrophoretic Separations; Joe Foley; Adam Socia; Donna M. Blackney; Detector Platform; Frank V. Bright; I E. Deuro

2012-01-01T23:59:59.000Z

208

Preliminary Screening | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Preliminary Screening Preliminary Screening Preliminary Screening October 16, 2013 - 5:12pm Addthis The first step in assessing renewable energy options is to conduct a preliminary screening to decide which technologies are worth investigating and which can be eliminated immediately. Preliminary screening involves using resource maps and other basic tools to choose technologies to pursue further. This should occur in the planning phase and can be completed at the agency level with some simple training. There should be no need to hire an outside consultant at this stage. When narrowing technology options during this phase of assessment, a range of factors are considered, such as: Available Renewable Resources Ability to Connect to the Grid Available Renewable Resources Renewable energy resources refer to the amount of energy that can be

209

A TCL/TK widget for display of MEDM screens.  

Science Conference Proceedings (OSTI)

A new Tcl/Tk widget has been created to display MEDM screens inside a Tcl/Tk application. Tcl/Tk parses the MEDM input files and the appropriate widgets are created and linked to the associated process variables. One advantage of this approach is that an X-Windows emulator is not required to view and manipulate the MEDM screen under a Windows operating system. Another benefit is that the MEDM screen can now be tightly integrated into a scripting language to attach higher-level logic to various process variable manipulations. Further details and examples of the new widget will be discussed.

Soliday, R.; APS Operations Division

2005-01-01T23:59:59.000Z

210

Former Worker Medical Screening Program | Department of Energy  

NLE Websites -- All DOE Office Websites (Extended Search)

Former Worker Medical Screening Program Former Worker Medical Screening Program The Former Worker Medical Screening Program (FWP) provides ongoing medical screening examinations,...

211

Mixed Alcohol Synthesis Catalyst Screening  

DOE Green Energy (OSTI)

National Renewable Energy Laboratory (NREL) and Pacific Northwest National Laboratory (PNNL) are conducting research to investigate the feasibility of producing mixed alcohols from biomass-derived synthesis gas (syngas). PNNL is tasked with obtaining commercially available or preparing promising mixed-alcohol catalysts and screening them in a laboratory-scale reactor system. Commercially available catalysts and the most promising experimental catalysts are provided to NREL for testing using a slipstream from a pilot-scale biomass gasifier. From the standpoint of producing C2+ alcohols as the major product, it appears that the rhodium catalyst is the best choice in terms of both selectivity and space-time yield (STY). However, unless the rhodium catalyst can be improved to provide minimally acceptable STYs for commercial operation, mixed alcohol synthesis will involve significant production of other liquid coproducts. The modified Fischer-Tropsch catalyst shows the most promise for providing both an acceptable selectivity to C2+ alcohols and total liquid STY. However, further optimization of the Fischer-Tropsch catalysts to improve selectivity to higher alcohols is highly desired. Selection of a preferred catalyst will likely entail a decision on the preferred coproduct slate. No other catalysts tested appear amenable to the significant improvements needed for acceptable STYs.

Gerber, Mark A.; White, James F.; Stevens, Don J.

2007-09-03T23:59:59.000Z

212

NRC LICENSE RENEWAL SCOPING/SCREENING INSPECTION  

E-Print Network (OSTI)

Dear Mr. Nazar: On May 21, 2004, the NRC completed an inspection regarding the application for license renewal for the D. C Cook Nuclear Plant. The enclosed report documents the inspection results, which were discussed with members of your staff. The purpose of this inspection was an examination of activities that support the application for a renewed license for D. C. Cook. The inspection consisted of a selected examination of procedures and representative records, and interviews with personnel regarding the process of scoping and screening plant equipment to select equipment subject to an aging management review. The inspection concluded that the scoping and screening portion of license renewal activities was conducted as described in the License Renewal Application and that documentation supporting the application is in an auditable and retrievable form. With the exception of the items identified in this report, your scoping and screening process was successful in identifying those systems, structures, and components required to be considered for aging management. In accordance with 10 CFR 2.390 of the NRCs "Rules of Practice, " a copy of this letter and its enclosure will be available electronically for public inspection in the NRC Public Document Room or from the Publicly Available Records (PARS) component of NRCs document system (ADAMS). ADAMS is accessible from the NRC Web site at

Cynthia D. Pederson; M. Finissi; Plant Manager; G. White; Michigan Public; Service Commission

2004-01-01T23:59:59.000Z

213

Former Worker Medical Screening Program - Battelle Laboratories...  

NLE Websites -- All DOE Office Websites (Extended Search)

West Jefferson Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Battelle...

214

Former Worker Medical Screening Program - Portsmouth Gaseous...  

NLE Websites -- All DOE Office Websites (Extended Search)

Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Portsmouth Worker Population...

215

Former Worker Medical Screening Program - Battelle Laboratories...  

NLE Websites -- All DOE Office Websites (Extended Search)

King Avenue Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Battelle...

216

Former Worker Medical Screening Program Implementation | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Former Worker Medical Screening Program Implementation Former Worker Medical Screening Program Implementation Program implementation focuses on four specific activities, which are:...

217

Former Worker Medical Screening Program - Brookhaven National...  

NLE Websites -- All DOE Office Websites (Extended Search)

Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Brookhaven National Laboratory...

218

Former Worker Medical Screening Program - Mallinckrodt Chemical...  

NLE Websites -- All DOE Office Websites (Extended Search)

Mallinckrodt Chemical Co. Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE...

219

Brookhaven National Laboratory, Former Production Workers Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Workers Screening Projects Brookhaven National Laboratory, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site:...

220

Nevada, Former Production Workers Screening Projects | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Nevada, Former Production Workers Screening Projects Nevada, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site: NNSS and...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Pantex Former Workers, Construction Worker Screening Project...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Pantex Former Workers, Construction Worker Screening Project Pantex Former Workers, Construction Worker Screening Project Project Name: Former Pantex Worker Medical Surveillance...

222

Former Worker Medical Screening Program - Related Documents ...  

NLE Websites -- All DOE Office Websites (Extended Search)

Workers at Los Alamos National Laboratory Former Worker Medical Screening Program for the Ames Laboratory and the Iowa Army Ammunition Plant National Supplemental Screening Program...

223

Interpretation of screen factor measurements  

SciTech Connect

Screen viscometer measurements give different information about polymer molecular weight and molecular weight distribution than intrinsic viscosity or relative viscosity measurements. This study shows that conventional screen viscometers measure elongation flow properties of solutions, and that for flexible polymers such as polyacrylamides, a sharp transition in conformation from a coiled to a stretched state is observed, which occurs at a Deborah number of 0.5. Conventional screen viscometers operate just above this critical Deborah number. Evidence for this transition in polymer conformation comes from measurements on a modified screen viscometer, from extensive work by Durst and Interhal on the sudden pressure jumps during flow of polyacrylamide solutions through porous media, and from polymer kinetic theory modeling of molecular deformation in flow. ll references.

Lim, T.; Uhl, J.T.; Prud'Homme, R.K.

1983-08-01T23:59:59.000Z

224

Light-scattering properties of a woven shade-screen material used for daylighting and solar heat-gain control  

E-Print Network (OSTI)

thermal and daylighting impacts of shading systems. Theseglazing the system. Modern energy and daylighting analysissystem. In this paper a shade screen used in the LBNL daylighting

Jonsson, Jacob C.

2008-01-01T23:59:59.000Z

225

Ames Laboratory, Former Production Workers Screening Projects...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Laboratory, Former Production Workers Screening Projects Ames Laboratory, Former Production Workers...

226

Argonne National Laboratory, Former Production Workers Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Former Production Workers Screening Projects Argonne National Laboratory, Former Production Workers...

227

Sandia National Laboratory (NM), Former Production Workers Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

, Former Production Workers Screening Projects Sandia National Laboratory (NM), Former Production Workers Screening Projects...

228

Hadronic Screening in Improved Taste  

E-Print Network (OSTI)

We present our results on meson and nucleon screening masses in finite temperature two flavour QCD using smeared staggered valence quarks and staggered thin-link sea quarks with different lattice spacings and quark masses. We investigate optimization of smearing by observing its effects on the infrared (IR) and ultraviolet (UV) components of gluon and quark fields. The application of smearing to screening at finite temperature also provides a transparent window into the mechanism of the interplay of smearing and chiral symmetry. The improved hadronic operators show that above the finite temperature cross over, T_c, screening masses are consistent with weak-coupling predictions. There is also evidence for a rapid opening up of a spectral gap of the Dirac operator immediately above T_c.

Sourendu Gupta; Nikhil Karthik

2013-02-20T23:59:59.000Z

229

Document Control Template-Instruction_Screen Shot  

NLE Websites -- All DOE Office Websites (Extended Search)

3_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 1 of 6 3_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 1 of 6 EOTA - Business Instruction Document Title: Document Control Template - Instruction-Screen Shot Document Number: F-003 Rev. A Document Owner: Elizabeth Sousa Backup Owner: Melissa Otero Approver(s): Melissa Otero Parent Document: P-001, Document Control Process Notify of Changes: EOTA Employees Referenced Document(s): N/A F-003_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 2 of 6 Revision History: Rev. Description of Change A Initial Release B C D E F-003_ADocument Control Template - Instruction_Screen Shot.doc_Screen ShotPage 3 of 6 EOTA - Business Instruction Document Title: DocTitle Document Number:

230

Walla Walla River Basin Fish Screens Evaluations, 2006 Annual Report.  

DOE Green Energy (OSTI)

Pacific Northwest National Laboratory evaluated Gardena Farms, Little Walla Walla, and Garden City/Lowden II Phase II fish screen facilities and provided underwater videography beneath a leaking rubber dam in the Walla Walla River basin in 2006. Evaluations of the fish screen facilities took place in early May 2006, when juvenile salmonids are generally outmigrating. At the Gardena Farms site, extended high river levels caused accumulations of debris and sediment in the forebay. This debris covered parts of the bottom drum seals, which could lead to early deterioration of the seals and drum screen. Approach velocities were excessive at the upstream corners of most of the drums, leading to 14% of the total approach velocities exceeding 0.4 feet per second (ft/s). Consequently, the approach velocities did not meet National Marine Fisheries Service (NMFS) design criteria guidelines for juvenile fish screens. The Little Walla Walla site was found to be in good condition, with all approach, sweep, and bypass velocities within NMFS criteria. Sediment buildup was minor and did not affect the effectiveness of the screens. At Garden City/Lowden II, 94% of approach velocities met NMFS criteria of 0.4 ft/s at any time. Sweep velocities increased toward the fish ladder. The air-burst mechanism appears to keep large debris off the screens, although it does not prevent algae and periphyton from growing on the screen face, especially near the bottom of the screens. In August 2006, the Gardena Farm Irrigation District personnel requested that we look for a leak beneath the inflatable rubber dam at the Garden City/Lowden II site that was preventing water movement through the fish ladder. Using our underwater video equipment, we were able to find a gap in the sheet piling beneath the dam. Erosion of the riverbed was occurring around this gap, allowing water and cobbles to move beneath the dam. The construction engineers and irrigation district staff were able to use the video footage to resolve the problem within a couple weeks. We had hoped to also evaluate the effectiveness of modifications to louvers behind the Nursery Bridge screens when flows were higher than 350 cubic feet per second, (cfs) but were unable to do so. Based on the one measurement made in early 2006 after the modified louvers were set, it appears the modified louvers may help reduce approach velocities. The auxiliary supply water system gates also control water through the screens. Evaluating the effect of different combinations of gate and louver positions on approach velocities through the screens may help identify optimum settings for both at different river discharges.

Chamness, Mickie; Abernethy, Scott; Tunnicliffe, Cherylyn [Pacific Northwest National Laboratory

2007-01-01T23:59:59.000Z

231

DOE: Former Worker Medical Screening Program (FWP)  

Energy.gov (U.S. Department of Energy (DOE))

FWP provides no-cost medical screenings to all former DOE Federal, contractor and subcontractor employees. The screening exams are offered by third party providers from universities, labor unions,...

232

DOE: Former Worker Medical Screening Program (FWP) | Department...  

NLE Websites -- All DOE Office Websites (Extended Search)

Former Worker Medical Screening Program (FWP) DOE: Former Worker Medical Screening Program (FWP) Addthis Description FWP provides no-cost medical screenings to all former DOE...

233

Rocky Flats, Former Production Workers Screening Projects | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Flats, Former Production Workers Screening Projects Rocky Flats, Former Production Workers Screening Projects Project Name: National Supplemental Screening Program Covered DOE...

234

Kansas City Plant, Construction Worker Screening Projects | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Kansas City Plant, Construction Worker Screening Projects Kansas City Plant, Construction Worker Screening Projects Project Name: Building Trades National Medicl Screening Program...

235

Kansas City Plant, Former Production Workers Screening Projects...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Kansas City Plant, Former Production Workers Screening Projects Kansas City Plant, Former Production Workers Screening Projects Project Name: National Supplemental Screening...

236

Distribution Screening for Distributed Generation  

Science Conference Proceedings (OSTI)

As the deployment of renewable distributed generation increases, the need for traditional energy providers to interact with these resources increases. Detailed modeling and simulation of the distribution and distributed resources is a critical element to better analyze, understand and predict these interactions. EPRI has developed a tool for such analysis called OpenDSS. In addition, as part of the renewable integration program an applet was created for screening distributed generation (DG). This report ...

2009-12-23T23:59:59.000Z

237

Demand Response Screening Assessment Tool Version 1.0  

Science Conference Proceedings (OSTI)

The Demand Response Screeing Tool for Distribution Planners identifies opportunities for using demand response as a distribution resource. It serves as a screening tool to assist distribution planners to ascertain situations where demand response may be a cost45effective alternative to making distribution system asset investments. WindowsXP, Excel (MS Office 2003)

2010-12-06T23:59:59.000Z

238

Coal storage hopper with vibrating screen agitator  

DOE Patents (OSTI)

The present invention is directed to a vibrating screen agitator in a coal storage hopper for assuring the uniform feed of coal having sufficient moisture content to effect agglomeration and bridging thereof in the coal hopper from the latter onto a conveyor mechanism. The vibrating screen agitator is provided by a plurality of transversely oriented and vertically spaced apart screens in the storage hopper with a plurality of vertically oriented rods attached to the screens. The rods are vibrated to effect the vibration of the screens and the breaking up of agglomerates in the coal which might impede the uniform flow of the coal from the hopper onto a conveyer.

Daw, Charles S. (Knoxville, TN); Lackey, Mack E. (Oak Ridge, TN); Sy, Ronald L. (Clinton, TN)

1984-01-01T23:59:59.000Z

239

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion  

E-Print Network (OSTI)

, Changchun 130000, China; d Department of Ophthalmology, Harbin Medical University, The Second Affiliated Hospital, Harbin, Heilongjiang 150086, China; e National Center for Advancing Translational Sciences targets for the development of neuroprotective drugs, we developed a high-throughput RNA in- terference

Dong, Xinzhong

240

Reverberatory screen for a radiant burner  

DOE Patents (OSTI)

The present invention relates to porous mat gas fired radiant burner panels utilizing improved reverberatory screens. The purpose of these screens is to boost the overall radiant output of the burner relative to a burner using no screen and the same fuel-air flow rates. In one embodiment, the reverberatory screen is fabricated from ceramic composite material, which can withstand higher operating temperatures than its metallic equivalent. In another embodiment the reverberatory screen is corrugated. The corrugations add stiffness which helps to resist creep and thermally induced distortions due to temperature or thermal expansion coefficient differences. As an added benefit, it has been unexpectedly discovered that the corrugations further increase the radiant efficiency of the burner. In a preferred embodiment, the reverberatory screen is both corrugated and made from ceramic composite material.

Gray, Paul E. (North East, MD)

1999-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
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they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Conventional Medical Screening Program | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Conventional Medical Screening Program Conventional Medical Screening Program Conventional Medical Screening Program Medical screening is a strategy used to identify diseases or conditions in a select population at an early stage, often before signs and symptoms develop, and to refer individuals with suspicious findings to their personal physician or a specialist for further testing, diagnosis, and treatment. The program is not intended to serve as a substitute for routine medical exams through an individual's personal physician. The medical screening exam offered by the FWP evaluates an employee's health as it relates to their potential occupational exposures to hazardous agents. The FWP uses a customized medical screening protocol that was developed by a team of independent physicians specializing in occupational

242

Amchitka Former Workers, Construction Worker Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Amchitka Former Workers, Construction Worker Screening Projects Amchitka Former Workers, Construction Worker Screening Projects Amchitka Former Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Amchitka Worker Population Served: All workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

243

Automated imaging system for single molecules  

SciTech Connect

There is provided a high throughput automated single molecule image collection and processing system that requires minimal initial user input. The unique features embodied in the present disclosure allow automated collection and initial processing of optical images of single molecules and their assemblies. Correct focus may be automatically maintained while images are collected. Uneven illumination in fluorescence microscopy is accounted for, and an overall robust imaging operation is provided yielding individual images prepared for further processing in external systems. Embodiments described herein are useful in studies of any macromolecules such as DNA, RNA, peptides and proteins. The automated image collection and processing system and method of same may be implemented and deployed over a computer network, and may be ergonomically optimized to facilitate user interaction.

Schwartz, David Charles; Runnheim, Rodney; Forrest, Daniel

2012-09-18T23:59:59.000Z

244

Former Worker Medical Screening Program - Lawrence Livermore...  

NLE Websites -- All DOE Office Websites (Extended Search)

Livermore National Laboratory Former Workers Former Worker Medical Screening Program (FWP) Project Name: Worker Health Protection Program Covered DOE Site: LLNL...

245

Improving Screening Strategies for Prostate Cancer.  

E-Print Network (OSTI)

??Th is thesis describes research on screening for prostate cancer. To improve understanding of the thesis, some background information will be provided in this introduction. (more)

Wolters, T.

2010-01-01T23:59:59.000Z

246

Preliminary Screening for Project Feasibility and Applications...  

NLE Websites -- All DOE Office Websites (Extended Search)

Best Practices Preliminary Screening for Project Feasibility and Applications for Geothermal Heat Pump Retrofit Projects GHPs Should Always be Considered for Federal Sites...

247

Beryllium Vender Screening Program | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Worker » Former Worker Program » Beryllium Worker » Former Worker Program » Beryllium Vender Screening Program Beryllium Vender Screening Program In February 2005, DOE expanded the beryllium screening program to include former employees of defunct DOE beryllium vendors who were employed with these companies while they performed work for DOE. This change was made to ensure that workers who no longer have an employer to turn to for beryllium disease testing could receive this important screening. DOE will offer these individuals a blood test at no cost to check for beryllium sensitization. DOE will pay for both the costs of drawing the blood and the analysis of the blood. If a screened individual receives an abnormal test for beryllium sensitization, they can receive medical monitoring for beryllium disease

248

Production Worker Screening Projects | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Production Worker Screening Projects Production Worker Screening Projects Sites listed below are the primary DOE sites served. Production workers from DOE sites not listed below are covered by the National Supplemental Screening Program (NSSP). Additional information regarding NSSP can be found on their website or by calling 1-866-812-6703. California: Lawrence Berkeley National Laboratory Lawrence Livermore National Laboratory Sandia National Laboratories (Livermore, CA) Colorado: Rocky Flats Florida: Pinellas Idaho: Argonne National Laboratory-West Idaho National Laboratory Illinois: Argonne National Laboratory Fermi National Accelerator Laboratory Iowa: Ames Laboratory Iowa Army Ammunition Plant Kentucky: Paducah Gaseous Diffusion Plant Missouri: Kansas City Plant Nevada:

249

Construction Worker Screening Projects | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Worker » Former Worker Program » Worker » Former Worker Program » Construction Worker Screening Projects Construction Worker Screening Projects Sites listed below are the primary DOE sites served. Construction workers from DOE sites not listed below are covered by the Building Trades National Medical Screening Program (BTMed). Additional information regarding BTMed can be found on their website or by calling 1-800-866-9663. Alaska: Amchitka California: Lawrence Berkeley National Laboratory Lawrence Livermore National Laboratory Sandia National Laboratories (Livermore, CA) Colorado: Rocky Flats Florida: Pinellas Idaho: Argonne National Laboratory-West Idaho National Laboratory Illinois: Argonne National Laboratory Fermi National Accelerator Laboratory Iowa: Ames Laboratory Iowa Army Ammunition Plant

250

An Improved Beam Screen for the LHC Injection Kickers  

E-Print Network (OSTI)

The two LHC injection kicker magnet systems must produce a kick of 1.3 T.m with a flattop duration variable up to 7860 ns, and rise and fall times of less than 900 ns and 3000 ns, respectively. Each system is composed of two resonant charging power supplies (RCPSs) and four 5 WW transmission line kicker magnets with matched terminating resistors and pulse forming networks (PFNs). A beam screen is placed in the aperture of the magnets: the screen consists of a ceramic tube with conductors on the inner wall. The conductors provide a path for the image current of the, high intensity, LHC beam and screen the ferrite against Wake fields. The conductors initially used gave adequately low beam coupling impedance however inter-conductor discharges occurred during pulsing of the magnet: an alternative design was discharge free at the nominal operating voltage but the impedance was too high for the ultimate LHC beam. This paper presents the results of a new development undertaken to meet the often conflicting requireme...

Barnes, M J; Ducimetire, L; Garrel, N; Kroyer, T

2007-01-01T23:59:59.000Z

251

Validation of Density Functional Theory for Materials  

Science Conference Proceedings (OSTI)

... One of the the crucial aspects in high-throughput computational screening of metal-organic frameworks (MOFs) for carbon capture and other ...

2013-07-18T23:59:59.000Z

252

Former Worker Medical Screening Program - Pinellas Former Construction...  

NLE Websites -- All DOE Office Websites (Extended Search)

Pinellas Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Pinellas...

253

Former Worker Medical Screening Program - Mound Former Construction...  

NLE Websites -- All DOE Office Websites (Extended Search)

Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Mound Worker Population...

254

Former Worker Medical Screening Program - Brush Luckey Plant...  

NLE Websites -- All DOE Office Websites (Extended Search)

Brush Luckey Plant Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site:...

255

Former Worker Medical Screening Program - Weldon Spring Plant...  

NLE Websites -- All DOE Office Websites (Extended Search)

Weldon Spring Plant Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site:...

256

Former Worker Medical Screening Program - Amchitka Former Workers  

NLE Websites -- All DOE Office Websites (Extended Search)

Amchitka Former Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Amchitka Worker Population...

257

Former Worker Medical Screening Program - Pinellas Former Production...  

NLE Websites -- All DOE Office Websites (Extended Search)

Production Workers Former Worker Medical Screening Program (FWP) Project Name: National Supplemental Screening Program Covered DOE Site: Pinellas Worker Population Served:...

258

Former Worker Medical Screening Program - Savannah River Site...  

NLE Websites -- All DOE Office Websites (Extended Search)

Production Workers Former Worker Medical Screening Program (FWP) Project Name: National Supplemental Screening Program Covered DOE Site: SRS Worker Population Served: Production...

259

Former Worker Medical Screening Program - Paducah Gaseous Diffusion...  

NLE Websites -- All DOE Office Websites (Extended Search)

Paducah Gaseous Diffusion Plant Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE...

260

Former Worker Medical Screening Program - Fernald Former Construction...  

NLE Websites -- All DOE Office Websites (Extended Search)

Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Fernald Worker Population...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Former Worker Medical Screening Program - Savannah River Site...  

NLE Websites -- All DOE Office Websites (Extended Search)

Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: SRS Worker Population Served:...

262

Former Worker Medical Screening Program - Oak Ridge Reservation...  

NLE Websites -- All DOE Office Websites (Extended Search)

Reservation Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medical Screening Program Covered DOE Site: Oak Ridge K-25...

263

Waste Isolation Pilot Plant, Former Production Workers Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Workers Screening Projects Waste Isolation Pilot Plant, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site:...

264

Former Worker Medical Screening Program - Kansas City Plant Former...  

NLE Websites -- All DOE Office Websites (Extended Search)

Kansas City Plant Former Construction Workers Former Worker Medical Screening Program (FWP) Project Name: Building Trades National Medicl Screening Program Covered DOE Site: Kansas...

265

Joint Outreach Task Group Former Workers Screening Program |...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Joint Outreach Task Group Former Workers Screening Program Joint Outreach Task Group Former Workers Screening Program The Joint Outreach Task Group (JOTG) includes representatives...

266

Argonne National Laboratory-West, Former Production Workers Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Workers Screening Projects (now known as the Idaho National Laboratory) Argonne National Laboratory-West, Former Production Workers Screening Projects (now known as...

267

Sandia National Laboratory (CA), Former Production Workers Screening...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

, Former Production Workers Screening Projects Sandia National Laboratory (CA), Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered...

268

Agency-Wide Screening | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Agency-Wide Screening Agency-Wide Screening Agency-Wide Screening October 16, 2013 - 4:36pm Addthis Federal agencies face energy-related requirements on new construction projects and major renovations. These Federal requirements range from reductions in fossil-fuel use to specifying the use of certain renewable energy technologies. As some agencies have already found out, not all sites or construction projects are created equal. Because many of the requirements are agency-wide, an effective and efficient way to meet these requirements is to consider and identify appropriate locations for these technologies across all agency land and building assets. FEMP can help Federal agencies conduct a renewable energy screening at all of its sites, or just at all of its upcoming construction project

269

Smart Screen Management on Mobile Phones  

E-Print Network (OSTI)

an energy management strategy that uses the history of userthe energy consumed by the deterministic schedules historyenergy pro?le of a mobile phone screen, and the usage history

Falaki, Hossein; Govindan, Ramesh; Estrin, D

2009-01-01T23:59:59.000Z

270

Design of the CTX diagnostics screen room  

DOE Green Energy (OSTI)

The design of a shielded enclosure (or screen room) to house data acquisition equipment in an area in which substantial, time varying magnetic fields are present and capable of producing significant interference is described.

Chandler, G.I. II

1981-01-01T23:59:59.000Z

271

Sensors for Screening and Surveillance  

SciTech Connect

Much attention, in fact an entire session at this conference, is being devoted to protecting the United States against human threats--individuals who may pose a danger by their mere presence on US soil. However, tomorrow's terrorists will employ weapons in their attacks, and we must also be diligent in preventing these weapons from reaching their targets. Sensors can play an important role in detecting these weapons before they achieve their desired effects. A sensor system can best be understood as a way of automating search techniques that would normally be carried out by a human's touch and vision senses, or by a dog's sniffing capabilities. The list of potential threats is long, including nuclear, biological, chemical and radiological weapons, and each presents its own challenges. However, any effective system must meet the following requirements: (1) Sensor systems must be operationally practical. Delays must be kept to a minimum. The systems must be safe to operate. Individual privacy and corporate proprietary information must be protected. The systems must be part of a viable concept of operations; i.e., they must provide information that can enable effective, preemptive actions to be taken. (2) Sensors systems must be highly sensitive, providing a low probability of missed detections (false negatives). Our adversaries will conceal their device from detection, and they will likely probe our defenses for any weaknesses. Our systems must be robust against these techniques. (3) Sensor systems must give a low probability of false alarms (false positives). Our response to the detection of such a weapon will marshal substantial resources and, in many scenarios, be highly disruptive to the general population. Thus a system that gives frequent false alarms will soon be ignored.

Dye, D.H.

2002-03-05T23:59:59.000Z

272

New mammography screen/film combinations: Imaging characteristics and radiation dose  

Science Conference Proceedings (OSTI)

Five types of film (Kodak OM, Kodak OM-SO177, Konica CM, Dupont Microvision, and Fuji MiMa) exposed in combination with seven different intensifying screens (Min R, Min R Medium, Siemens Orthox MA, Kyokka HR Mammo Fine, Agfa Gevaert Detail S (old and new), and Konica Monarch) were processed for either 90 sec (at 33.3{degrees}C) or 3 min (at 35.0 degrees C). The films imaged a Computerized Imaging Reference System phantom with additional detail test objects placed on its surface to produce four groups of objects with which to evaluate resolution and contrast. For objects that tested resolution, the Kyokka HR Mammo Fine (Fuji) screen was statistically significantly superior; for objects that tested contrast, the Konica Monarch screen was statistically significantly superior. Extended processing did not affect Dupont and Kodak OM film as much as it affected the other films. It did affect contrast for the other films tested. The mean glandular doses from gridless exposures ranged from 32 to 80 mrad (0.32-0.80 mGy) over all film/screen/processing combinations for a 4.5-cm-thick test object. Several new film/screen combinations can provide images superior to the Kodak Min R/OM combination at a reduced radiation dose. The Kyokka HR Mammo Fine (Fuji) screen was found statistically superior in radiographic resolution of mammographic test objects and the Konica Monarch screen was found to be superior in defining contrast.

Kimme-Smith, C.; Bassett, L.W.; Gold, R.H.; Zheutlin, J.; Gornbein, J.A. (Iris Cantor Center for Breast Imaging, CA (USA))

1990-04-01T23:59:59.000Z

273

Washington Phase II Fish Diversion Screen Evaluations in the Yakima River Basin, 1997 Annual Report.  

DOE Green Energy (OSTI)

The Pacific Northwest National Laboratory evaluated 19 Phase II screen sites in the Yakima River Basin at least three times each between April 30 and August 22, 1997. The sites were examined to determine if they were being effectively operated and maintained to provide fish a safe, efficient return to the river. Data were collected to determine if velocities in front of the screens and in the bypass met current NMFS criteria and promoted timely fish bypass, if fish were protected from injury due to impingement, entrainment, and predation, and whether bypass outfall conditions allowed fish to safely return to the river. A bi-directional flow meter and underwater video system were essential in completing the investigation. In general, water velocity conditions at the screen sites were acceptable by NMFS standards. High approach velocities and slow bypass flow were the most common problems noted. Although velocities often fluctuated from one sampling location to the next, average sweep and approach velocities were very good. In general, fish should not be impinged or experience delays in returning to the river under normal operating conditions. Most screens were properly sealed to prevent fish entrainment and injury, although potential problems were identified at several screen sites. Three sites had gap openings from the forebay to the aftbay, allowing fish to be entrained. Other sites had spaces larger than 3/32 inch where small fish could become trapped. Some drum screens had flat spots but these were not been confirmed as underwater gaps, primarily because of siltation. On rare occasions, seals were intact, but cracked or turned under. Submergence levels at the drum screen sites exceeded 85% for one third of our evaluations. Eight of 12 drum screen sites experienced high water levels during at least one evaluation. Only one operating site's submergence was measured at less than 65% submergence. Two flat plate screen sites were completely overtopped with water during one evaluation each. Although 1997 was an extreme high-water year, these overtopping events point out that some screens do not completely protect fish under the full range of potential operating conditions. Water depths at the outfall pipe were acceptable at all but four sites. Generally, water depths were low near the end of the irrigation season due to low river flows. Rock removal around the outfall pipe or pipe extension would improve the situation. We gauged the potential for predation by qualitatively measuring the types and amount of cover provided for predators in front of the screens and by recording random observations of fish large enough to be considered predators in the forebay. Predation was more likely to occur at drum screen sites than at flat plate screen sites. Drum sites provide more predator hiding places because greater amounts of woody debris accumulate under the drums and against the concrete walls that divide one screen bay from the next. Four sites had both woody debris and large fish present. These four sites were considered most likely to experience juvenile salmonid loss to predation. Periodic removal of woody debris from underneath the curvature of drum screens would decrease the likelihood of predation at these sites. Screens were generally well maintained. Automated cleaning brushes functioned properly, chains and other moving parts were well greased, and inoperative and algae-covered drum screens were eventually repaired and cleaned. However, removal of sediment build-up and accumulated woody debris are areas where improvement should be considered. Maintenance checks should include observation of bypass outfalls on a regular basis, as conditions at the end of the bypass pipe are likely to change seasonally, especially in streams with high gradients or unstable gravel. Post-season evaluations were conducted at 11 sites in November to try and confirm seal and drum screen defects, and locations of excessive sedimentation. This proved effective in several cases, but the winterization process eliminated some of the evidence. Severa

Blanton, S.; Neitzel, C.; Abernethy, C. (Pacific Northwest National Laboratory)

1998-02-01T23:59:59.000Z

274

The First Extrasolar Planet Discovered with a New Generation High Throughput Doppler Instrument  

E-Print Network (OSTI)

We report the detection of the first extrasolar planet, ET-1 (HD 102195b), using the Exoplanet Tracker (ET), a new generation Doppler instrument. The planet orbits HD 102195, a young star with solar metallicity that may be part of the local association. The planet imparts radial velocity variability to the star with a semiamplitude of $63.4\\pm2.0$ m s$^{-1}$ and a period of 4.11 days. The planetary minimum mass ($m \\sin i$) is $0.488\\pm0.015$ $M_J$.

Jian Ge; Julian van Eyken; Suvrath Mahadevan; Curtis DeWitt; Stephen R. Kane; Roger Cohen; Andrew Vanden Heuvel; Scott W. Fleming; Pengcheng Guo; Gregory W. Henry; Donald P. Schneider; Lawrence W. Ramsey; Robert A. Wittenmyer; Michael Endl; William D. Cochran; Eric B. Ford; Eduardo L. Martin; Garik Israelian; Jeff Valenti; David Montes

2006-05-10T23:59:59.000Z

275

High Throughput Ab initio Modeling of Charge Transport for Bio-Molecular-Electronics  

E-Print Network (OSTI)

1.2.2 Bio-Assembled CNT Field Effect Transistors . . . .nanotube - peptide nucleic acid bio conjugates for molecularmetallization for conductive bio-inorganic interfaces in

Bruque, Nicolas A.

2009-01-01T23:59:59.000Z

276

SAFA: Semi-automated footprinting analysis software for high-throughput quantification of nucleic acid  

E-Print Network (OSTI)

inspection is frequently sufficient for a qualitative analysis, quantification of the relative propor- tions. 1979; Ackers et al. 1982; Celander and Cech 1990, 1991), the timescales for folding events (Sclavi et

Herschlag, Dan

277

High-throughput Characterization of Porous Materials Using Graphics Processing Units  

E-Print Network (OSTI)

is supported by the Office of Science of the U.S. Departmentby the Director, Office of Science, Advanced ScientificDepartment of Energy, Office of Science, Office of Basic

Kim, Jihan

2013-01-01T23:59:59.000Z

278

Treatability studies on different refinery wastewater samples using high-throughput microbial electrolysis cells (MECs)  

E-Print Network (OSTI)

for the first time. Bioelectrochemical treatability was evaluated relative to oxygen demand. MECs were-oiled refinery wastewater sample from one site (DOW1) produced the best results, with 2.1 ± 0.2 A/m2 (maximum current density), 79% chemical oxygen demand removal, and 82% headspace biological oxygen demand removal

279

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity  

E-Print Network (OSTI)

Institute of Biochemical Sciences, National Taiwan University, Taipei, 106, Taiwan, Republic of China developed resistance towards current drugs, new inhibitors that prevent viral replication through differ prophylactics for controlling influenza infections. Other prophylactic and therapeutic antiviral drugs

Tsai, Ming-Daw

280

Network-based classification of recurrent endometrial cancers using high-throughput DNA methylation data  

Science Conference Proceedings (OSTI)

DNA methylation, a well-studied mechanism of epigenetic regulation, plays important roles in cancer. Increased levels of global DNA methylation is observed in primary solid tumors including endometrial carcinomas and is generally associated with silencing ... Keywords: DNA methylation, Steiner tree, cancer recurrence, classification, protein-protein interaction network, random walk

Jianhua Ruan; Md. Jamiul Jahid; Fei Gu; Chengwei Lei; Yi-Wen Huang; Ya-Ting Hsu; David G. Mutch; Chun-Liang Chen; Nameer B. Kirma; Tim H. Huang

2012-10-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Ultra-high-aspect-ratio nanofluidic channels for high-throughput biological applications  

E-Print Network (OSTI)

The development of micro/nanofluidics is expected to be the enabling technology for sample preparation of proteomic biosamples, which has been the bottleneck in proteomics. Most microfabricated nanofluidic channels, such ...

Mao, Pan

2009-01-01T23:59:59.000Z

282

High throughput lessons from the LHC experience.Johnston.TNC2013  

NLE Websites -- All DOE Office Websites (Extended Search)

transmission is the "C" band, which is 1530 nm to 1565 nm. (The optical spectrum of human vision is about 380 nm - 700 nm, and so 1530 nm is well into the infrared.) In...

283

Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray  

E-Print Network (OSTI)

Atomic force microscopy has been applied to an acrylate polymer microarray to achieve a full topographic characterisation. This process discovered a small number of hydro-responsive materials created from monomers with ...

Hook, Andrew L.

284

Categorizing Biases in High-Confidence High-Throughput Protein-Protein Interaction  

E-Print Network (OSTI)

A to serotonin, followed by product and then CoA The S5/S6 loop creates one wall of a narrow canyon- release., Nilges, M., Pannu, N.S., and Read, Shales, D., Shimizu, K., and Shaw, K.J. (1997). The most frequent R

285

Operations capability improvement of a molecular biology laboratory in a high throughput genome sequencing center  

E-Print Network (OSTI)

The Broad Institute is a research collaboration of MIT, Harvard University and affiliated hospitals, and the Whitehead Institute for Biomedical Research. Its scientific mission is to "(1) create tools for genomic medicine ...

Vokoun, Matthew R. (Matthew Richard)

2005-01-01T23:59:59.000Z

286

Empirical Bayesian analysis of paired high-throughput sequencing data with a beta-binomial distribution  

E-Print Network (OSTI)

-throughput sequencing experiments. We examine the performance of this method on simulated and real data in a variety of scenarios. Our methods are implemented as part of the RbaySeq package (versions 1.11.6 and greater) available from Bioconductor (http...

Hardcastle, Thomas J; Kelly, Krystyna A

2013-04-23T23:59:59.000Z

287

Analysis of High-Throughput Sequencing and Annotation Strategies for Phage Genomes  

E-Print Network (OSTI)

Background: Bacterial viruses (phages) play a critical role in shaping microbial populations as they influence both host mortality and horizontal gene transfer. As such, they have a significant impact on local and global ...

Chisholm, Sallie (Penny)

288

High-Throughput Compression of FASTQ Data with SeqDB  

Science Conference Proceedings (OSTI)

Compression has become a critical step in storing next-generation sequencing (NGS) data sets because of both the increasing size and decreasing costs of such data. Recent research into efficiently compressing sequence data has focused largely on improving ... Keywords: Throughput,Arrays,Bandwidth,Libraries,Bioinformatics,Instruction sets,Genomics,FASTQ,Compression,data storage,next-generation sequencing

Mark Howison

2013-01-01T23:59:59.000Z

289

Data structures and compression algorithms for high-throughput sequencing technologies  

E-Print Network (OSTI)

applications ranging from genome sequencing and resequencingthe point where human genome sequencing will be a commodity.questions, from genome sequencing to transcription fac- tor

Daily, Kenny; Rigor, Paul; Christley, Scott; Xie, Xiaohui; Baldi, Pierre

2010-01-01T23:59:59.000Z

290

The Development of a High-throughput Microdroplet Bioreactor Device for Microbial Studies  

E-Print Network (OSTI)

Microdroplet microfluidics has gained much interested in the past decade due to its ability to conduct a wide variety of biological and microfluidic experiments with extremely high repeatability on a mass scale. In particular the ability to culture multiple batches of cells by creating microdroplets with a single encapsulated cell and observe their growth overtime allows for specific conditioning of cells. In addition, when conducting co-culture experiment the induction of a certain stimulus may provide observational rare differences in growth that may be characterized by harnessing a single batch of cells out of thousands of samples. This thesis first presents a variety of microdroplet microfluidic devices that use specific techniques to sufficiently produce, synchronize, merge, and analyze microdroplets. Although many of the devices are capable of producing stable droplets and somewhat efficient synchronization, the overall merging efficiency for most passive or active merging methods alone is lacking. Improvements on such methods and the incorporation of multiple merging methods can lead to a higher overall merging efficiency and greater droplet stability. Also, multiple droplet detection methods can be employed to analyze cellular growth under different conditions, while passive or active sorting methods can be used to acquire particular microdroplet samples downstream. The work presented in this thesis entails the characterization and detailed analysis of all aspects of microdroplet microfluidics necessary to adequately produce a microdroplet co-culture device for microbial studies. This includes the incorporation of multiple microdroplet generators for the production of water droplets immersed in oil serving as bio-reactors for cell culture experiments. In addition, multiple microdroplet synchronization devices were tested to sufficiently align multiple trains of droplets for downstream merging using a variety of passive, active, or combination merging methods. In particular, the use of an electric field can cause destabilization of the surfactant surrounding a microdroplet and allow for the formation of a liquid bridge. The formation of this liquid bridge in conjunction with passive merging methods can lead to droplet electrocoalescence. The incorporation of a more uniform electric field that reduces the angle between the droplet dipole moment and E-field can lead to better droplet merging while reducing voltage and frequency requirements observed in previously publications. The testing, observation, and optimization of such aspects of microdroplet microfluidics are crucial for the advancement and production of sound microdroplet culture devices for a variety of applications including the analysis of dangerous pathogenic substances, drug testing or delivery, and genetic studies.

Guzman, Adrian

2012-08-01T23:59:59.000Z

291

Encoded hydrogel microparticles for high-throughput molecular diagnostics and personalized medicine  

E-Print Network (OSTI)

The ability to accurately detect and quantify biological molecules in complex mixtures is crucial in basic research as well as in clinical settings. Advancements in genetic analysis, molecular diagnostics, and patient-tailored ...

Chapin, Stephen Clifford

2012-01-01T23:59:59.000Z

292

Examination of mammalian microRNAs by high-throughput sequencing  

E-Print Network (OSTI)

Small non-coding RNAs play an important role in a wide range of cellular events. MicroRNAs (miRNAs) are an abundant class of small RNAs that post-transcriptionally repress expression of their target genes. Since miRNA ...

Chiang, HyoJin Rosaria

2011-01-01T23:59:59.000Z

293

Novel CdTe Cell Fabrication Process with Potential for Low Cost and High Throughput  

DOE Green Energy (OSTI)

There are several production disadvantages inherent in the conventional SnO(2)/CdS/CdTe manufacturing processes. In this paper, we report a novel manufacturing process for fabrication of polycrystalline Cd(2)SnO(4)/Zn(2)/SnO(4)/CdS/CdTe thin-film solar cells that yielded a CdS/CdTe device with an NREL-confirmed efficiency of 14.0%.

Wu, X.; Sheldon, P.

2000-01-01T23:59:59.000Z

294

High-throughput microfluidic living cell arrays for spatiotemporal gene expression profiling  

E-Print Network (OSTI)

The cellular microenvironment is remarkably complex. In the small space near each cell, growth factors are liberated from extracellular matrix, cytokines are secreted from neighboring cells, and hormones arrive from distant ...

King, Kevin R. (Kevin Robert), 1976-

2008-01-01T23:59:59.000Z

295

HiCT: High Throughput Protocols For CPE Cloning And Transformation  

E-Print Network (OSTI)

The purpose of this RFC is to provide instructions for a rapid and cost efficient cloning and transformation method which allows for the manufacturing of multi-fragment plasmid constructs in a parallelized manner: High ...

Beer, Ralf

2013-10-04T23:59:59.000Z

296

Characterization and High Throughput Analysis of Metal Hydrides for Hydrogen Storage  

E-Print Network (OSTI)

L. Schlapbach, Ed. , Hydrogen as a Future Energy Carrier .M.S. Dresselhaus, Int. J. Hydrogen Energy 33 (2008) 4122-Kojima, T. Haga, Int. J. Hydrogen Energy 28 9 (2003) 989-993

Barcelo, Steven James

2009-01-01T23:59:59.000Z

297

High-throughput Characterization of Porous Materials Using Graphics Processing Units  

E-Print Network (OSTI)

A.E. ; Purcell, T. Computer Graphics Forum 2007, 26(1), 80-of Porous Materials Using Graphics Processing Units Jihanof Porous Materials Using Graphics Processing Units Jihan

Kim, Jihan

2013-01-01T23:59:59.000Z

298

High-throughput, single-worm tracking and analysis in Caenorhabditis elegans  

E-Print Network (OSTI)

felt lost, he led me back on course to complete the work herein. There is so much more I would love to mention, regarding my thanks for his instruction, but there is insufficient space and I would not even know where to begin. I am forever indebted... , which later led to focused investigation of the underlying mutated genes and eventual elucidation of their function. Numerous examples come as a result of Sydney Benners classic work. One particularly early example is the discovery of a gene function...

Yemini, Eviatar

2013-01-08T23:59:59.000Z

299

Application of phage display to high throughput antibody generation and characterisation  

E-Print Network (OSTI)

, moderate staining of spermatid tails observed#7;Present in murine spermatogenesis (Maekawa M, Suzuki-Toyota F, Toyama Y et al. Arch Histol Cytol, 1998, 61: 405). The staining patterns match those described by Nakai M, Chen L, Nowak RA. Annat Record, 2006...

Schofield, Darren J; Pope, Anthony R; Clementel, Veronica; Buckell, Jenny; Chapple, Susan D J; Clarke, Kay F; Conquer, Jennie S; Crofts, Anna M; Crowther, Sandra R E; Dyson, Michael R; Flack, Gillian; Griffin, Gareth J; Hooks, Yvette; Howat, William J; Kolb-Kokocinski, Anja; Kunze, Susan; Martin, Cecile D; Maslen, Gareth L; Mitchell, Joanne N; O'Sullivan, Maureen; Perera, Rajika L; Roake, Wendy; Shadbolt, S Paul; Vincent, Karen J; Warford, Anthony; Wlson, Wendy E; Xie, Jane; Young, Joyce L; McCafferty, John

2007-11-29T23:59:59.000Z

300

Bayesian Model Selection for High-dimensional High-throughput Data  

E-Print Network (OSTI)

Bayesian methods are often criticized on the grounds of subjectivity. Furthermore, misspecified priors can have a deleterious effect on Bayesian inference. Noting that model selection is effectively a test of many hypotheses, Dr. Valen E. Johnson sought to eliminate the need of prior specification by computing Bayes' factors from frequentist test statistics. In his pioneering work that was published in the year 2005, Dr. Johnson proposed using so-called local priors for computing Bayes? factors from test statistics. Dr. Johnson and Dr. Jianhua Hu used Bayes' factors for model selection in a linear model setting. In an independent work, Dr. Johnson and another colleage, David Rossell, investigated two families of non-local priors for testing the regression parameter in a linear model setting. These non-local priors enable greater separation between the theories of null and alternative hypotheses. In this dissertation, I extend model selection based on Bayes' factors and use nonlocal priors to define Bayes' factors based on test statistics. With these priors, I have been able to reduce the problem of prior specification to setting to just one scaling parameter. That scaling parameter can be easily set, for example, on the basis of frequentist operating characteristics of the corresponding Bayes' factors. Furthermore, the loss of information by basing a Bayes' factors on a test statistic is minimal. Along with Dr. Johnson and Dr. Hu, I used the Bayes' factors based on the likelihood ratio statistic to develop a method for clustering gene expression data. This method has performed well in both simulated examples and real datasets. An outline of that work is also included in this dissertation. Further, I extend the clustering model to a subclass of the decomposable graphical model class, which is more appropriate for genotype data sets, such as single-nucleotide polymorphism (SNP) data. Efficient FORTRAN programming has enabled me to apply the methodology to hundreds of nodes. For problems that produce computationally harder probability landscapes, I propose a modification of the Markov chain Monte Carlo algorithm to extract information regarding the important network structures in the data. This modified algorithm performs well in inferring complex network structures. I use this method to develop a prediction model for disease based on SNP data. My method performs well in cross-validation studies.

Joshi, Adarsh

2010-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Journal of Power Sources 158 (2006) 6068 High throughput evaluation of perovskite-based anode catalysts  

E-Print Network (OSTI)

.R. Narayanan, E. Vamos, H. Frank, G. Halpert, A. LaConti, J. Kosek, G.K. Surya Prakash, G.A. Olah, J. Power

Mukasyan, Alexander

302

Inch-Scale High Throughput Metrology of Graphene and Patterned Graphene Oxide  

E-Print Network (OSTI)

Strength of Monolayer Graphene Science 2008 321, 385-388. 5.Novoselov, K. S. The rise of graphene Nature 2007 6 183-191.A. Thermal properties of graphene and nanostructured carbon

Pleskot, Dennis

2013-01-01T23:59:59.000Z

303

Development and implementation of high-throughput SNP genotyping in barley  

E-Print Network (OSTI)

knowledge of the marker order than does a linear map derivedthat this does not guar- antee that the marker order in the

2009-01-01T23:59:59.000Z

304

High Throughput Ab initio Modeling of Charge Transport for Bio-Molecular-Electronics  

E-Print Network (OSTI)

the contacts. The potential energy matrix U represents the? U 0,0 ] ?1 . The self-energy matrices are calculated fromand adding the self-energy matrices ? and ? r onto the new

Bruque, Nicolas A.

2009-01-01T23:59:59.000Z

305

High-throughput analysis of chromosome translocations and other genome rearrangements in epithelial cancers  

E-Print Network (OSTI)

, 448:561-566. 5. Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM... . Howarth KD, Blood KA, Ng BL, Beavis JC, Chua Y, Cooke SL, Raby S, Ichimura K, Collins VP, Carter NP, Edwards PA: Array painting reveals a high frequency of balanced translocations in breast cancer cell lines that break in cancer- relevant genes. Oncogene...

Newman, Scott; Edwards, Paul A W

2010-03-17T23:59:59.000Z

306

High Throughput Ab initio Modeling of Charge Transport for Bio-Molecular-Electronics  

E-Print Network (OSTI)

resonant tunneling diode (RTD) for electronic circuitstructure to perform as an RTD. A resonant level lies closecharacteristics of an RTD. The I-V has a peak magnitude of 4

Bruque, Nicolas A.

2009-01-01T23:59:59.000Z

307

Evaluation of a New Remote Handling Design for High Throughput Annular Centrifugal Contactors  

Science Conference Proceedings (OSTI)

Advanced designs of nuclear fuel recycling plants are expected to include more ambitious goals for aqueous based separations including; higher separations efficiency, high-level waste minimization, and a greater focus on continuous processes to minimize cost and footprint. Therefore, Annular Centrifugal Contactors (ACCs) are destined to play a more important role for such future processing schemes. Previous efforts defined and characterized the performance of commercial 5 cm and 12.5 cm single-stage ACCs in a cold environment. The next logical step, the design and evaluation of remote capable pilot scale ACCs in a hot or radioactive environment was reported earlier. This report includes the development of remote designs for ACCs that can process the large throughput rates needed in future nuclear fuel recycling plants. Novel designs were developed for the remote interconnection of contactor units, clean-in-place and drain connections, and a new solids removal collection chamber. A three stage, 12.5 cm diameter rotor module has been constructed and evaluated for operational function and remote handling in highly radioactive environments. This design is scalable to commercial CINC ACC models from V-05 to V-20 with total throughput rates ranging from 20 to 650 liters per minute. The V-05R three stage prototype was manufactured by the commercial vendor for ACCs in the U.S., CINC mfg. It employs three standard V-05 clean-in-place (CIP) units modified for remote service and replacement via new methods of connection for solution inlets, outlets, drain and CIP. Hydraulic testing and functional checks were successfully conducted and then the prototype was evaluated for remote handling and maintenance suitability. Removal and replacement of the center position V-05R ACC unit in the three stage prototype was demonstrated using an overhead rail mounted PaR manipulator. This evaluation confirmed the efficacy of this innovative design for interconnecting and cleaning individual stages while retaining the benefits of commercially reliable ACC equipment for remote applications in the nuclear industry. Minor modifications and suggestions for improved manual remote servicing by the remote handling specialists were provided but successful removal and replacement was demonstrated in the first prototype.

David H. Meikrantz; Troy G. Garn; Jack D. Law; Lawrence L. Macaluso

2009-09-01T23:59:59.000Z

308

High-throughput Characterization of Porous Materials Using Graphics Processing Units  

E-Print Network (OSTI)

Science, Advanced Scientific Computing Research, of the U.S.the Office of Advanced Scientific Computing Research throughScience, Advanced Scientific Computing Research, of the U.S.

Kim, Jihan

2013-01-01T23:59:59.000Z

309

High-throughput Evaluation of Crystallization Temperature of Pd-Cu ...  

Science Conference Proceedings (OSTI)

Temperature and Magnetic Field Dependence of Electrical Resistance in Trilayer and Fourlayer Graphene ... Tool Failure Criteria while Drilling Titanium Alloys.

310

Development of a high throughput 3D perfused liver tissue bioreactor  

E-Print Network (OSTI)

This thesis describes the development of a device designed for culturing liver tissue in a 3D perfused environment. Cells form tissue inside miniature channels of a scaffold, and the tissue is perfused with culture medium ...

Inman, Samuel Walker

2006-01-01T23:59:59.000Z

311

An ultra-high throughput mutational spectrometer for human genetic diagnostics  

E-Print Network (OSTI)

Discovering the genetic causes of common diseases may require scanning for mutations in all of the genes in a million people, a significant undertaking. Such discoveries would revolutionize biotechnology, potentially ...

Forest, Craig Richard, 1978-

2007-01-01T23:59:59.000Z

312

NMAC Circulating and Service Water Intake Screens and Debris Removal Equipment Maintenance Guide  

Science Conference Proceedings (OSTI)

Power plants use many different types of equipment to remove trash, debris, and aquatic material at the intake structures for circulating and service water systems. Commonly used equipment includes rotating and stationary screens, trash racks, debris filters, service water strainers, and debris disposal systems.

2004-12-15T23:59:59.000Z

313

CHEMICAL SENSOR AND FIELD SCREENING TECHNOLOGY DEVELOPMENT: FUELS IN SOILS FIELD SCREENING METHOD VALIDATION  

DOE Green Energy (OSTI)

A new screening method for fuel contamination in soils was recently developed as American Society for Testing and Materials (ASTM) Method D-583 1-95, Standard Test Method for Screening Fuels in Soils. This method uses low-toxicity chemicals and can be used to screen organic-rich soils. In addition, it is fast, easy, and inexpensive to perform. The screening method calls for extracting a sample of soil with isopropyl alcohol following treatment with calcium oxide. The resulting extract is filtered, and the ultraviolet absorbance of the extract is measured at 254 nm. Depending on the available information concerning the contaminant fuel type and availability of the contaminant fuel for calibration, the method can be used to determine the approximate concentration of fuel contamination, an estimated value of fuel contamination, or an indication of the presence or absence of fuel contamination. Fuels containing aromatic compounds, such as diesel fuel and gasoline, as well as other aromatic-containing hydrocarbon materials, such as motor oil, crude oil, and coal oil, can be determined. The screening method for fuels in soils was evaluated by conducting a collaborative study on the method and by using the method to screen soil samples at an actual field site. In the collaborative study, a sand and an organic soil spiked with various concentrations of diesel fuel were tested. Data from the collaborative study were used to determine the reproducibility (between participants) and repeatability (within participant) precision of the method for screening the test materials. The collaborative study data also provide information on the performance of portable field equipment versus laboratory equipment for performing the screening method and a comparison of diesel concentration values determined using the screening method versus a laboratory method. Data generated using the method to screen soil samples in the field provide information on the performance of the method in atypical real-world application.

Susan S. Sorini; John F. Schabron

1997-04-01T23:59:59.000Z

314

RENEWABLE ENERGY SCREENING FOR ALL ESPCs  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RENEWABLE ENERGY SCREENING FOR ALL ESPCs RENEWABLE ENERGY SCREENING FOR ALL ESPCs The Department of Energy's (DOE) Federal Energy Management Program (FEMP) Energy Savings Performance Contracts (ESPC) program has funded DOE National Laboratories to support agencies with increasing use of renewable energy technologies required per EPACT 2005 and Executive Order 13423. To utilize the no-cost support, the National Laboratories require some easily accessible high-level site and related energy data to conduct pre- screening analysis. The objective is to identify the economic feasibility of renewable technologies - wind, solar, and biomass power generation applications - that could be considered as Energy Conservation Measures (ECMs) in your ESPC. The National Laboratories commit to turning around

315

Dainippon Screen Mfg Co | Open Energy Information  

Open Energy Info (EERE)

Dainippon Screen Mfg Co Dainippon Screen Mfg Co Jump to: navigation, search Name Dainippon Screen Mfg Co Place Kyoto, Kyoto, Japan Sector Solar Product Japan-based company engaged in the manufacture and sale of electronic equipment and image information processing and solar PV product production equipment Coordinates 35.098129°, 135.718933° Loading map... {"minzoom":false,"mappingservice":"googlemaps3","type":"ROADMAP","zoom":14,"types":["ROADMAP","SATELLITE","HYBRID","TERRAIN"],"geoservice":"google","maxzoom":false,"width":"600px","height":"350px","centre":false,"title":"","label":"","icon":"","visitedicon":"","lines":[],"polygons":[],"circles":[],"rectangles":[],"copycoords":false,"static":false,"wmsoverlay":"","layers":[],"controls":["pan","zoom","type","scale","streetview"],"zoomstyle":"DEFAULT","typestyle":"DEFAULT","autoinfowindows":false,"kml":[],"gkml":[],"fusiontables":[],"resizable":false,"tilt":0,"kmlrezoom":false,"poi":true,"imageoverlays":[],"markercluster":false,"searchmarkers":"","locations":[{"text":"","title":"","link":null,"lat":35.098129,"lon":135.718933,"alt":0,"address":"","icon":"","group":"","inlineLabel":"","visitedicon":""}]}

316

Dynamic Scheduling of Skippable Periodic Tasks with Energy Efficiency in Weakly Hard Real-Time System  

E-Print Network (OSTI)

Energy consumption is a critical design issue in real-time systems, especially in battery- operated systems. Maintaining high performance, while extending the battery life between charges is an interesting challenge for system designers. Dynamic Voltage Scaling (DVS) allows a processor to dynamically change speed and voltage at run time, thereby saving energy by spreading run cycles into idle time. Knowing when to use full power and when not, requires the cooperation of the operating system scheduler. Usually, higher processor voltage and frequency leads to higher system throughput while energy reduction can be obtained using lower voltage and frequency. Instead of lowering processor voltage and frequency as much as possible, energy efficient real-time scheduling adjusts voltage and frequency according to some optimization criteria, such as low energy consumption or high throughput, while it meets the timing constraints of the real-time tasks. As the quantity and functional complexity of battery powered porta...

Baskaran, Santhi

2010-01-01T23:59:59.000Z

317

Water Velocity Measurements on a Vertical Barrier Screen at the Bonneville Dam Second Powerhouse  

Science Conference Proceedings (OSTI)

Fish screens at hydroelectric dams help to protect rearing and migrating fish by preventing them from passing through the turbines and directing them towards the bypass channels by providing a sweeping flow parallel to the screen. However, fish screens may actually be harmful to fish if they become impinged on the surface of the screen or become disoriented due to poor flow conditions near the screen. Recent modifications to the vertical barrier screens (VBS) at the Bonneville Dam second powerhouse (B2) intended to increase the guidance of juvenile salmonids into the juvenile bypass system (JBS) have resulted in high mortality and descaling rates of hatchery subyearling Chinook salmon during the 2008 juvenile salmonid passage season. To investigate the potential cause of the high mortality and descaling rates, an in situ water velocity measurement study was conducted using acoustic Doppler velocimeters (ADV) in the gatewell slot at Units 12A and 14A of B2. From the measurements collected the average approach velocity, sweep velocity, and the root mean square (RMS) value of the velocity fluctuations were calculated. The approach velocities measured across the face of the VBS varied but were mostly less than 0.3 m/s. The sweep velocities also showed large variances across the face of the VBS with most measurements being less than 1.5 m/s. This study revealed that the approach velocities exceeded criteria recommended by NOAA Fisheries and Washington State Department of Fish and Wildlife intended to improve fish passage conditions.

Hughes, James S.; Deng, Zhiqun; Weiland, Mark A.; Martinez, Jayson J.; Yuan, Yong

2011-11-22T23:59:59.000Z

318

Virtual screening on large scale grids  

Science Conference Proceedings (OSTI)

Large scale grids for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale virtual docking within the framework of the WISDOM initiative against ... Keywords: Avian influenza, Large scale grids, Malaria, Virtual screening

Nicolas Jacq; Vincent Breton; Hsin-Yen Chen; Li-Yung Ho; Martin Hofmann; Vinod Kasam; Hurng-Chun Lee; Yannick Legr; Simon C. Lin; Astrid Maa; Emmanuel Medernach; Ivan Merelli; Luciano Milanesi; Giulio Rastelli; Matthieu Reichstadt; Jean Salzemann; Horst Schwichtenberg; Ying-Ta Wu; Marc Zimmermann

2007-05-01T23:59:59.000Z

319

Sharing the viewing experience through second screens  

Science Conference Proceedings (OSTI)

Despite the ever expanding forms of digital entertainment and the emergence of consumer recording facilities, allowing viewers to time shift their TV viewing habits, there are still certain TV shows and events that create an audience desire to be part ... Keywords: interactive, mobile, narrative, performance, second screen, shared experience, television, twitter

Mark Lochrie; Paul Coulton

2012-07-01T23:59:59.000Z

320

Former Worker Medical Screening Program Brochure | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Medical Screening Program Brochure Medical Screening Program Brochure Former Worker Medical Screening Program Brochure June 2012 The FWP brochure provides important information to inform former and current DOE Federal, contractor, and subcontractor employees about the benefits and services offered under the DOE Former Worker Medical Screening Program. Some of the topics described in the brochure include: a description of the program, how it is implemented, who is eligible to participate, what tests are offered, where exams are conducted, and what organizations provide the exams. Former Worker Medical Screening Program Brochure More Documents & Publications Former Worker Program Brochure Former Worker Program Summary of Services 2012 Former Worker Medical Screening Program Annual Report

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

D & D screening risk evaluation guidance  

SciTech Connect

The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D&D) facilities. Although this method has been developed for D&D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D&D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis.

Robers, S.K.; Golden, K.M.; Wollert, D.A.

1995-09-01T23:59:59.000Z

322

Light-scattering properties of a woven shade-screen material used for  

NLE Websites -- All DOE Office Websites (Extended Search)

Light-scattering properties of a woven shade-screen material used for Light-scattering properties of a woven shade-screen material used for daylighting and solar heat-gain control Title Light-scattering properties of a woven shade-screen material used for daylighting and solar heat-gain control Publication Type Conference Paper LBNL Report Number LBNL-828E Year of Publication 2008 Authors Jonsson, Jacob C., Eleanor S. Lee, and Michael D. Rubin Conference Name SPIE Optics+Photonics Date Published 08/2008 Conference Location San Diego, CA Call Number LBNL-828E Abstract Shade-screens are widely used in commercial buildings as a way to limit the amount of direct sunlight that can disturb people in the building. The shade screens also reduce the solar heat-gain through glazing the system. Modern energy and daylighting analysis software such as EnergyPlus and Radiance require complete scattering properties of the scattering materials in the system.

323

1  

NLE Websites -- All DOE Office Websites (Extended Search)

Global health response more accurate Global health response more accurate with automated influenza surveillance January 31, 2011 LANL to certify automated influenza surveillance A compact, self-contained, automated system for surveillance and screening of potential pandemic strains of influenza and other deadly infectious diseases is a step closer to reality, thanks to an agreement between Los Alamos National Laboratory, the University of California Los Angeles School of Public Health, and HighRes Biosolutions of Boston, Massachussets. Researchers from LANL and the UCLA School of Public Health will test and certify a critical component of the High-Throughput Laboratory Network (HTLN) to be built by HighRes Biosolutions. The company will design the automated high-throughput extraction and screening system for a prototype Global Bio Lab-a compact, modular

324

Site-specific waste management instruction - radiological screening facility  

DOE Green Energy (OSTI)

This Site-Specific Waste Management Instruction provides guidance for managing waste generated from radiological sample screening operations conducted to support the Environmental Restoration Contractor`s activities. This document applies only to waste generated within the radiological screening facilities.

G. G. Hopkins

1997-12-31T23:59:59.000Z

325

Microfluidic in vivo screen identifies compounds enhancing neuronal  

E-Print Network (OSTI)

Compound screening is a powerful tool to identify new therapeutic targets, drug leads, and elucidate the fundamental mechanisms of biological processes. We report here the results of the first in vivo small-molecule screens ...

Haggarty, Stephen

326

Laboratory Evaluation of Fine-mesh Traveling Water Screens  

Science Conference Proceedings (OSTI)

This report presents final results of four years of laboratory evaluations on performance of fine-mesh traveling water screens to protect larval fish at cooling water intake structures (CWISs). Prior to this study, the biological effectiveness of fine-mesh screens was uncertain because performance data from the few existing facilities that use fine-mesh screens have been highly variable. This project is producing additional data necessary to determine biological efficacy of fine-mesh screens.

2010-12-21T23:59:59.000Z

327

Guidance for Developing Ecological Soil Screening Levels  

NLE Websites -- All DOE Office Websites (Extended Search)

Developing Developing Ecological Soil Screening Levels OSWER Directive 9285.7-55 U.S. Environmental Protection Agency Office of Solid Waste and Emergency Response 1200 Pennsylvania Avenue, N.W. Washington, DC 20460 November 2003 This Page Intentionally Left Blank EXECUTIVE SUMMARY This document describes the process used to derive a set of risk-based ecological soil screening levels (Eco-SSLs) for many of the soil contaminants that are frequently of ecological concern for plants and animals at hazardous waste sites and provides guidance for their use. The Eco-SSL derivation process represents the group effort of a multi-stakeholder workgroup consisting of federal, state, consulting, industry, and academic participants led by the U.S. Environmental Protection Agency Office of Superfund Remediation and Technology Innovation (OSRTI). The

328

The interpretation of screen-factor measurements  

SciTech Connect

Screen-factor (SF) measurements are widely used in the petroleum industry to characterize polymer solutions. The measurements are easy to perform and provide information that is different from solution-viscosity measurements. However, there has been no quantitative explanation of what solution property is being measured by SF. The authors show that SF measures the elongational viscosity of a polymer solution. Experiments on a modified commercial screen viscometer show the relationship between SF measurements and elongational-flow measurements performed by Durst and coworkers. Durst has shown that the elongational flow field in a packed bed of spheres triggers a transition in the conformation of a flexible polymer molecule, such as polyacrylamide, from a coiled to a stretched state. This transition in conformation is accompanied by a jump in the resistance to flow by an order of magnitude. They show that conventional screen viscometers operate in the regime where the molecules are in the highly stretched state. On the basis of Durst's work, it is calculated that the SF measurement is sensitive to high-molecular-weight tails in the polymer molecular-weight distribution.

Lim, T.; Uhl, J.T.; Prud'homme, R.K.

1986-05-01T23:59:59.000Z

329

The Usage of Screen-Level Parameters and Microwave Brightness Temperature for Soil Moisture Analysis  

Science Conference Proceedings (OSTI)

This study focuses on testing two different soil moisture analysis systems based on screen-level parameters (2-m temperature T2m, 2-m relative humidity RH2m) and 1.4-GHz passive microwave brightness temperatures TB. First, a simplified extended ...

G. Seuffert; H. Wilker; P. Viterbo; M. Drusch; J-F. Mahfouf

2004-06-01T23:59:59.000Z

330

A supplement to the european guidelines for quality assurance in breast cancer screening and diagnosis  

Science Conference Proceedings (OSTI)

In 2006 the fourth edition of the European Guidelines for Breast Cancer Screening and Diagnosis was published by the European Commission Due to the fast developments in the field of digital mammography and the experience with digital mammography systems ... Keywords: mammography, quality control

Ruben E van Engen; Kenneth C. Young; Hilde Bosmans; Barbara Lazzari; Stephan Schopphoven; Patrice Heid; Martin Thijssen

2010-06-01T23:59:59.000Z

331

Drum Screen Filtration of Cooling Water in Fossil-Fired and Nuclear Power Plants: The Electricite de France (EDF) Experience  

Science Conference Proceedings (OSTI)

This document presents a summary of the lessons learned from operating the drum screen filtration systems used for the last three decades in lectricit de Frances (EDFs) nuclear and fossil-fired power plants, both in terms of the technological aspects of filtration and with regard to the prevention of clogging risks and the prevention of damage to the living organisms impinged on the drum screens and entrained into the cooling ...

2012-11-21T23:59:59.000Z

332

The Application of Monochromatic Energies to Investigate Multiphase Porous Media Systems using Synchrotron X-ray Tomography  

SciTech Connect

X-ray computed tomography (CT) is becoming a useful tool for nondestructive imaging of many geoenvironmental and geotechnical systems. Conventional X-ray CT systems typically utilize a polychromatic X-ray beam. While providing a high throughput of photons, the use of polychromatic energy can make quantifying material concentrations, densities or composition very difficult or impossible without appropriate standards. Synchrotron X-rays have an extremely small angular divergence, thus permitting spatial resolution that is only limited by the optical components of the system. In addition, the ability to tune to a monochromatic X-ray energy allows better phase contrast by reducing beam hardening and allowing for elemental discrimination. In this work we will show how monochromatic energy can be used to provide high-quality images allowing for phase separation several different porous media systems thus improving our ability to quantify a range of processes and phenomena.

Ham, Kyungmin; Willson, Clinton S. (LSU)

2006-01-31T23:59:59.000Z

333

Savannah River Site, Former Production Workers Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Site, Former Production Workers Screening Projects Site, Former Production Workers Screening Projects Savannah River Site, Former Production Workers Screening Projects Project Name: National Supplemental Screening Program Covered DOE Site: SRS Worker Population Served: Production Workers Principal Investigator: Donna Cragle, PhD Toll-free Telephone: (866) 812-6703 Website: http://www.orau.org/nssp/ This project is conducted by the Oak Ridge Associated Universities (ORAU), as a component of its National Supplemental Screening Program. ORAU has teamed with its partners, Comprehensive Health Services, National Jewish Health, the University of Colorado Denver, and Axion Health, to run the program. Construction Worker Screening Projects Construction Worker Projects, Former Worker Medical Screening Program (FWP)

334

Walkthrough screening evaluation field guide. Natural phenomena hazards at Department of Energy facilities: Revision 2  

SciTech Connect

The US Department of Energy (DOE) has a large inventory of existing facilities. Many of these facilities were not designed and constructed to current natural phenomena hazard (NPH) criteria. The NPH events include earthquakes, extreme winds and tornadoes, and floods. DOE Order 5480.28 establishes policy and requirements for NPH mitigation for DOE facilities. DOE is conducting a multiyear project to develop evaluation guidelines for assessing the condition and determining the need for upgrades at DOE facilities. One element of the NPH evaluation guidelines` development involves the existing systems and components at DOE facilities. This effort is described in detail in a cited reference. In the interim period prior to availability of the final guidelines, DOE facilities are encouraged to implement an NPH walk through screening evaluation process by which systems and components that need attention can be rapidly identified. Guidelines for conducting the walk through screening evaluations are contained herein. The result of the NPH walk through screening evaluation should be a prioritized list of systems and components that need further action. Simple and inexpensive fixes for items identified in the walk through as marginal or inadequate should be implemented without further study. By implementing an NPH walk through screening evaluation, DOE facilities may realize significant reduction in risk from NPH in the short term.

Eder, S.J. [EQE Engineering Consultants, San Francisco, CA (United States); Eli, M.W. [Lawrence Livermore National Lab., CA (United States); Salmon, M.W. [EQE Engineering Consultants, Irvine, CA (United States)

1993-11-01T23:59:59.000Z

335

Screening analysis of solar thermochemical hydrogen concepts.  

DOE Green Energy (OSTI)

A screening analysis was performed to identify concentrating solar power (CSP) concepts that produce hydrogen with the highest efficiency. Several CSP concepts were identified that have the potential to be much more efficient than today's low-temperature electrolysis technology. They combine a central receiver or dish with either a thermochemical cycle or high-temperature electrolyzer that operate at temperatures >600 C. The solar-to-hydrogen efficiencies of the best central receiver concepts exceed 20%, significantly better than the 14% value predicted for low-temperature electrolysis.

Diver, Richard B., Jr.; Kolb, Gregory J.

2008-03-01T23:59:59.000Z

336

Use of fish larva morphometry to predict exclusion capabilities of small-mesh screens at cooling-water intakes  

SciTech Connect

A relationship between total lengths and body depths of certain fish larvae was used to predict the effectiveness of small-mesh screens in limiting entrainment of fish larvae at cooling-water intakes. Total length-body depth regressions were linear for eight species (293 larvae) common to Lake Michigan near the J. H. Campbell Power Plant at Port Sheldon, Michigan. Regressions indicated that 35 to 100% (depending on species) of the fish larvae that had been entrained by the J. H. Campbell Plant in 1978 would have been excluded if 0.5-mm mesh screening had been employed in the plant's cooling water intake system instead of 9.5-mm bar mesh vertical traveling screens. These calculations do not take into consideration approach velocities of intake water, larva avoidance behavior, or mortality due to impingement on or extrusion through the screens.

Schneeberger, P.J.; Jude, D.J.

1981-03-01T23:59:59.000Z

337

Impact of Screening on Behavior During Storage and Cost of Ground Small-Diameter Pine Trees: A Case Study  

DOE Green Energy (OSTI)

Whole comminuted trees are known to self-heat and undergo quality changes during storage. Trommel screening after grinding is a process that removes fines from the screened material and removes a large proportion of high-ash, high-nutrient material. In this study, the trade-off between an increase in preprocessing cost from trommel screening and an increase in quality of the screened material was examined. Fresh lodgepole pine (Pinus contorta) was comminuted using a drum grinder with a 10-cm screen, and the resulting material was distributed into separate fines and overs piles. A third pile of unscreened material, the unsorted pile, was also examined. The three piles exhibited different characteristics during a 6-week storage period. The overs pile was much slower to heat. The overs pile reached a maximum temperature of 56.88 degrees C, which was lower than the maximum reached by the other two piles (65.98 degrees C and 63.48 degrees C for the unsorted and fines, respectively). The overs also cooled faster and dried to a more uniform moisture content and had a lower ash content than the other two piles. Both piles of sorted material exhibited improved airflow and more drying than the unsorted material. Looking at supply system costs from preprocessing through in-feed into thermochemical conversion, this study found that trommel screening reduced system costs by over $3.50 per dry matter ton and stabilized material during storage.

Erin Searcy; Brad D Blackwelder; Mark E Delwiche; Allison E Ray; Kevin L Kenney

2011-10-01T23:59:59.000Z

338

FIELD SCREENING FOR HALOGENATED VOLATILE ORGANIC COMPOUNDS: THE NEW X-WAND HVOC SCREENING DEVICE  

SciTech Connect

Western Research Institute (WRI) has developed new methodology and a test kit to screen soil or water samples for halogenated volatile organic compounds (HVOCs) in the field. The technology has been designated the X-Wand{trademark} screening tool. The new device uses a heated diode sensor that is commonly used to detect leaks of refrigerants from air conditioners, freezers, and refrigerators. This sensor is selective to halogens. It does not respond to volatile aromatic hydrocarbons, such as those in gasoline, and it is not affected by high humidity. In the current work, the heated diode leak detectors were modified further to provide units with rapid response and enhanced sensitivity. The limit of detection for trichloroethylene TCE in air is 0.1 mg/m{sup 3} (S/N = 2). The response to other HVOCS relative to TCE is similar. Variability between sensors and changes in a particular sensor over time can be compensated for by normalizing sensor readings to a maximum sensor reading at 1,000 mg/m{sup 3} TCE. The soil TCE screening method was expanded to include application to water samples. Assuming complete vaporization, the detection limit for TCE in soil is about 1 ug/kg (ppb) for a 25-g sample in an 8-oz jar. The detection limit for TCE in water is about 1 ug/L (ppb) for a 25-mL sample in an 8-oz jar. This is comparable to quantitation limits of EPA GC/MS laboratory methods. A draft ASTM method for screening TCE contaminated soils using a heated diode sensor was successfully submitted for concurrent main committee and subcommittee balloting in ASTM Committee D 34 on Waste Management. The method was approved as ASTM D 7203-05, Standard Test Method for Screening Trichloroethylene (TCE)-Contaminated Soil Using a Heated Diode Sensor.

John F. Schabron; Susan S. Sorini; Joseph F. Rovani Jr

2006-03-01T23:59:59.000Z

339

NEPA SCREENING FORM I Document Number: DOE/CX-00029 I-:::--=---:-------~----'-~---  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

SCREENING FORM SCREENING FORM I Document Number: DOE/CX-00029 I-:::--=---:-------~----'-~--- I. Project Title: Project L-691, 200 West Area Sanitary Sewage Lagoon n. Project Description and Location (including time period over which proposed action will occur and project dimensions - e.g., acres displaced/disturbed, excavation length/depth, etc.): Project L-691 will construct a sanitary sewage lagoon system near the 200 West Area of the Hanford Site. This sanitary sewage lagoon system will include a septage dump station, a multi-cell sewage lagoon plant, a septage stabilization facility, and an intermittent filter system with an evaporative lagoon. Current plans are to locate the new facility directly north of the 200 West Area perimeter fence line; near

340

Weldon Spring Plant, Former Construction Workers Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Workers Screening Projects Workers Screening Projects Weldon Spring Plant, Former Construction Workers Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Weldon Spring Plant Worker Population Served: Construction workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

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341

Hanford Former Workers, Construction Worker Screening Projects | Department  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Hanford Former Workers, Construction Worker Screening Projects Hanford Former Workers, Construction Worker Screening Projects Hanford Former Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Hanford Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Local Outreach Office: Sherry Gosseen 3021 W. Clearwater Ave., Ste. 204 Kennewick, WA 99336 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

342

Weldon Spring Plant, Former Construction Worker Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Weldon Spring Plant, Former Construction Worker Screening Projects Weldon Spring Plant, Former Construction Worker Screening Projects Weldon Spring Plant, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Weldon Spring Plant Worker Population Served: Construction workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

343

Former Worker Medical Screening Program Implementation | Department of  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Former Former Worker Medical Screening Program Implementation Former Worker Medical Screening Program Implementation Program implementation focuses on four specific activities, which are: Outreach: Identify and notify eligible DOE workers about FWP medical screening services. Medical Screening: Provide medical screening exams that are designed to check for health conditions related to occupational exposures to former workers who choose to participate in the program, including a re-screen exam every three years. Communicating Results: Provide exam results to participants, as well as information regarding any conditions that may require follow-up medical care with their personal physicians or specialists, and provide information regarding possible compensation for work-related illnesses. Follow-up care

344

2012 Former Worker Medical Screening Program Annual Report | Department of  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Information Center » Worker » Former Worker Program » 2012 Information Center » Worker » Former Worker Program » 2012 Former Worker Medical Screening Program Annual Report 2012 Former Worker Medical Screening Program Annual Report February 2013 The 2012 Annual Report presents a detailed overview of the accomplishments, progress, and future endeavors of the U.S. Department of Energy Former Worker Medical Screening Program. The report describes how the program is implemented, what organizations are involved in the medical screening efforts, and what the medical findings have been to date. 2012 Former Worker Medical Screening Program Annual Report More Documents & Publications Former Worker Program Medical Protocol Former Worker Medical Screening Program Brochure Former Worker Program Brochure DOE Technical Standards Program

345

Bush Administration to Expand Beryllium Disease Screening Program |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Bush Administration to Expand Beryllium Disease Screening Program Bush Administration to Expand Beryllium Disease Screening Program Bush Administration to Expand Beryllium Disease Screening Program February 23, 2005 - 10:27am Addthis Former employees of DOE vendors eligible for free screening WASHINGTON, DC - U.S. Secretary of Energy Samuel W. Bodman today announced the Department of Energy (DOE) will expand a beryllium screening program to include former employees of now-defunct DOE beryllium vendor companies across the country. Beryllium is a component used in nuclear weapons built by the Department of Energy. "Through no fault of their own, these Cold Warriors were left out in the cold when their former employers went out of business. By expanding this screening program, President Bush and the Department of Energy honor these

346

Paducah Gaseous Diffusion Plant, Construction Worker Screening Project |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Paducah Gaseous Diffusion Plant, Construction Worker Screening Paducah Gaseous Diffusion Plant, Construction Worker Screening Project Paducah Gaseous Diffusion Plant, Construction Worker Screening Project Project Name: Building Trades National Medical Screening Program Covered DOE Site: Paducah Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (888) 464-0009 Local Outreach Office: Joe Hudson 1930 North 13th Street Paducah, KY 42001 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

347

Federal Renewable Energy Screening Assistant | Open Energy Information  

Open Energy Info (EERE)

Federal Renewable Energy Screening Assistant Federal Renewable Energy Screening Assistant Jump to: navigation, search Tool Summary Name: Federal Renewable Energy Screening Assistant (FRESA) Agency/Company /Organization: NREL Sector: Energy Focus Area: Biomass, Solar, Wind Topics: Implementation Resource Type: Software/modeling tools Website: analysis.nrel.gov/fresa/ OpenEI Keyword(s): EERE tool, FRESA, Federal Renewable Energy Screening Assistant References: FRESA homepage [1] Logo: Federal Renewable Energy Screening Assistant (FRESA) FRESA, is designed to help identify which renewable energy technologies are appropriate for implementation at both the facility and building scale. The Federal Renewable Energy Screening Assistant, or FRESA, is designed to help identify which renewable energy technologies are appropriate for

348

Oak Ridge Reservation Former Workers, Construction Worker Screening  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Oak Ridge Reservation Former Workers, Construction Worker Screening Oak Ridge Reservation Former Workers, Construction Worker Screening Projects Oak Ridge Reservation Former Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Oak Ridge K-25 Gaseous Diffusion Plant, Y-12, Oak Ridge National Laboratory (ORNL or X-10) Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPh, MHA, MPH Toll-free Telephone: (888) 464-0009 Local Outreach Office: Kim Cranford, RN 708 South Illinois Avenue, Suite E103 Oak Ridge, TN 37830 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos,

349

Fernald, Former Construction Worker Screening Projects | Department of  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Fernald, Former Construction Worker Screening Projects Fernald, Former Construction Worker Screening Projects Fernald, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Fernald Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: 1-888-464-0009 Local Outreach Office: Lou Doll 1550 Chase Avenue Cincinnati, OH 45223 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

350

Waste Isolation Pilot Plant, Former Construction Worker Screening Projects  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Construction Worker Screening Construction Worker Screening Projects Waste Isolation Pilot Plant, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: WIPP Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPh, MHA, MPH Toll-free Telephone: (800) 866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

351

Brush Luckey Plant, Former Construction Worker Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Brush Luckey Plant, Former Construction Worker Screening Projects Brush Luckey Plant, Former Construction Worker Screening Projects Brush Luckey Plant, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Brush Luckey Plant Worker Population Served: Construction workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: 1-888-464-0009 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by CPWR - The Center for Construction Research and Training, an applied

352

Former Worker Program - Defunct Beryllium Vendor Screening Program  

NLE Websites -- All DOE Office Websites (Extended Search)

Defunct Beryllium Vendor Screening Program Defunct Beryllium Vendor Screening Program Former Worker Medical Screening Program (FWP) In February 2005, DOE expanded the beryllium screening program to include former employees of defunct DOE beryllium vendors who were employed with these companies while they performed work for DOE. This change was made to ensure that workers who no longer have an employer to turn to for beryllium disease testing could receive this important screening. DOE will offer these individuals a blood test at no cost to check for beryllium sensitization. DOE will pay for both the costs of drawing the blood and the analysis of the blood. If a screened individual receives an abnormal test for beryllium sensitization, they can receive medical monitoring for beryllium disease through DOL's EEOICP.

353

Bound Electron Screening Corrections to Reactions in Hydrogen Burning Processes  

E-Print Network (OSTI)

How important would be a precise assessment of the electron screening effect, on determining the bare astrophysical $S$-factor ($S_b(E)$) from experimental data? We compare the $S_b(E)$ obtained using different screening potentials, (1) in the adiabatic limit, (2) without screening corrections, and (3) larger than the adiabatic screening potential in the PP-chain reactions. We employ two kinds of fitting procedures: the first is by the conventional polynomial expression and the second includes explicitly the contribution of the nuclear interaction and based on a statistical model. Comparing bare $S$-factors that are obtained by using different screening potentials, all $S_b(E)$ are found to be in accord within the standard errors for most of reactions investigated, as long as the same fitting procedure is employed. $S_b(E)$ is, practically, insensitive to the magnitude of the screening potential.

Sachie Kimura; Aldo Bonasera

2006-11-20T23:59:59.000Z

354

Fuel Cell Technologies Office: HT Combinatorial Screening of Novel  

NLE Websites -- All DOE Office Websites (Extended Search)

HT Combinatorial HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) to someone by E-mail Share Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Facebook Tweet about Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Twitter Bookmark Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Google Bookmark Fuel Cell Technologies Office: HT Combinatorial Screening of Novel Materials for High Capacity Hydrogen Storage Video (Text Alternative) on Delicious Rank Fuel Cell Technologies Office: HT Combinatorial Screening of

355

Savannah River Site, Former Construction Worker Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Savannah River Site, Former Construction Worker Screening Projects Savannah River Site, Former Construction Worker Screening Projects Savannah River Site, Former Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: SRS Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Local Outreach Office: Charles Jernigan 1250 A Reynolds Street Augusta, GA 30901 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

356

Pinellas Former Construction Worker, Construction Worker Screening Projects  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Pinellas Former Construction Worker, Construction Worker Screening Pinellas Former Construction Worker, Construction Worker Screening Projects Pinellas Former Construction Worker, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Pinellas Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: 1-800-866-9663 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica and/or solvents. The project is being carried out by a large group led by

357

Hardware Accelerator for MIMO Wireless Systems  

E-Print Network (OSTI)

Ever increasing demand for higher data rates and better Quality of Service (QoS) for a growing number of users requires new transceiver algorithms and architectures to better exploit the available spectrum and to efficiently counter the impairments of the radio channel. Multiple-Input Multiple-Output (MIMO) communication systems employ multiple antennas at both transmitter and at the receiver to meet the requirements of next-generation wireless systems. It is a promising technology to provide increased data rates while not involving an equivalent increase in the spectral requirements. However, practical implementation of MIMO detectors poses a significant challenge and has been consistently identified as the major bottleneck for realizing the full potential that multiple antenna systems promise. Furthermore, in order to make judicious use of the available bandwidth, the baseband units have to dynamically adapt to different modes (modulation schemes, code rates etc) of operations. Flexibility and high throughput requirements often place conflicting demands on the Very Large Scale Integration (VLSI) system designer. The major focus of this dissertation is to present efficient VLSI architectures for configurable MIMO detectors that can serve as accelerators to enable the realization of next generation wireless devices feasible. Both, hard output and soft output detector architectures are considered.

Bhagawat, Pankaj

2011-12-01T23:59:59.000Z

358

Walla Walla River Basin Fish Screen Evaluations, 2003: Nursery Bridge Fishway and Garden City-Lowden II  

DOE Green Energy (OSTI)

The Pacific Northwest National Laboratory (PNNL) evaluated the fish screens at the Nursery Bridge Fishway and at the newly constructed Garden City-Lowden II site west of Walla Walla, Washington in the Walla Walla River Basin during the spring and summer of 2003. Both fish screen facilities were examined to determine if they were being effectively operated and maintained to provide for safe fish passage. At the Nursery Bridge Fishway, the screens were evaluated specifically to determine whether the louvers that aid in controlling water flow from behind the screens could be adjusted so that the screens would meet fish protection criteria. Data were collected to determine whether velocities in front of the screens and in the bypasses met current National Oceanic and Atmospheric Administration Fisheries ((NOAA Fisheries), formerly National Marine Fisheries Service (NMFS)) criteria to promote safe and timely fish passage before and after changing the louver settings. Rock weirs downstream of the dam were also evaluated to determine whether they might impede upstream migration of juvenile salmonids during low flow conditions. At the Garden City-Lowden II site, data were collected to establish a baseline for operating conditions and to determine whether any changes in the baffle settings were needed. Based on the results of our studies in 2003, we concluded: Nursery Bridge Site: (1) 68% of the initial velocity measurements on the west screen exceeded the NOAA Fisheries criteria of 0.4 ft/s for approach velocity; (2) A simple adjustment of the existing louvers was not sufficient to fix the problem; (3) The sediment and debris load in the river upstream of the screens exceeded the design criteria for the site, which had frequent breakdowns in the screen cleaning systems; and (4) The rock weirs downstream of the dam would not be expected to impede upstream movement of juvenile fish during low flow conditions. Garden City-Lowden II: (1) The flat inclined-plate screen design appeared to be efficiently protecting juvenile fish from entrainment, impingement and migration delay; (2) Approach velocities met the NMFS criteria of less than 0.4 ft/s in June, and no change in baffle settings was needed; (3) Sweep velocities were generally lower than approach velocities and did not increase toward the downstream end of the site; and (4) The automated cleaning system at the Garden City-Lowden II site works adequately when sediment loads are low, though its effectiveness at cleaning the screens decreases as sediment and debris loads and algal growth increase.

Vucelick, Jessica A.; McMichael, Geoffrey A.

2003-11-01T23:59:59.000Z

359

Light-scattering properties of a woven shade-screen material used for daylighting and solar heat-gain control  

Science Conference Proceedings (OSTI)

Shade-screens are widely used in commercial buildings as a way to limit the amount of direct sunlight that can disturb people in the building. The shade screens also reduce the solar heat-gain through glazing the system. Modern energy and daylighting analysis software such as EnergyPlus and Radiance require complete scattering properties of the scattering materials in the system. In this paper a shade screen used in the LBNL daylighting testbed is characterized using a photogoniometer and a normal angle of incidence integrating sphere. The data is used to create a complete bi-directional scattering distribution function (BSDF) that can be used in simulation programs. The resulting BSDF is compared to a model BADFs, both directly and by calculating the solar heat-gain coefficient for a dual pane system using Window 6.

Jonsson, Jacob; Jonsson, Jacob C.; Lee, Eleanor S.; Rubin, Mike

2008-08-01T23:59:59.000Z

360

Former Worker Medical Screening Program 2012 Annual Report  

NLE Websites -- All DOE Office Websites (Extended Search)

bureaus. Lou Doll, BTMed local outreach coordinator, participating at the Cincinnati AFL-CIO Labor Day Picnic. 6 * 2012 Former Worker Medical Screening Program However, from the...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Former Worker Medical Screening Program - Lawrence Berkeley National...  

NLE Websites -- All DOE Office Websites (Extended Search)

Berkeley National Laboratory Former Workers Former Worker Medical Screening Program (FWP) Project Name: Worker Health Protection Program Covered DOE Site: LBNL...

362

Former Worker Medical Screening Program - Nevada Former Workers  

NLE Websites -- All DOE Office Websites (Extended Search)

Nevada Former Workers Former Worker Medical Screening Program (FWP) Project Name: Worker Health Protection Program Covered DOE Site: NNSS and other DOE locations in Las Vegas...

363

Former Worker Medical Screening Program - Mound Former Production...  

NLE Websites -- All DOE Office Websites (Extended Search)

Production Workers Former Worker Medical Screening Program (FWP) Project Name: Worker Health Protection Program Covered DOE Site: Mound Worker Population Served: Production Workers...

364

Former Worker Medical Screening Program - Pantex Former Workers  

NLE Websites -- All DOE Office Websites (Extended Search)

Pantex Former Workers Former Worker Medical Screening Program (FWP) Project Name: Former Pantex Worker Medical Surveillance Program Covered DOE Site: Pantex Worker Population...

365

Former Worker Medical Screening Program - Sandia National Laboratory...  

NLE Websites -- All DOE Office Websites (Extended Search)

CA) Former Workers Former Worker Medical Screening Program (FWP) Project Name: Worker Health Protection Program Covered DOE Site: SNL (CA) Worker Population Served: All workers...

366

Former Worker Medical Screening Program - Oak Ridge Y-12 and...  

NLE Websites -- All DOE Office Websites (Extended Search)

Y-12 and Oak Ridge National Laboratory Former Production Workers Former Worker Medical Screening Program (FWP) Project Name: Worker Health Protection Program Covered DOE Site: Y-12...

367

Roof screening for underground coal mines: recent developments  

Science Conference Proceedings (OSTI)

The use of screens to control falls of the immediate roof or roof skin (that is between the installed primary and secondary roof supports) is described. 5 figs.

Compton, C.S.; Gallagher, S.; Molinda, G.M.; Mark, C.; Wilson, G.

2008-06-15T23:59:59.000Z

368

Former Worker Medical Screening Program - Kansas City Plant Former...  

NLE Websites -- All DOE Office Websites (Extended Search)

(FWP) Project Name: National Supplemental Screening Program Covered DOE Site: Kansas City Plant Worker Population Served: Production workers Principal Investigator: Donna...

369

Handheld Touch Screen Device May Lead to Mobile ...  

Science Conference Proceedings (OSTI)

Handheld Touch Screen Device May Lead to Mobile Fingerprint ID. ... rescue teams lug around to aid in their anti-terrorism efforts, and this led to NIST ...

2010-10-08T23:59:59.000Z

370

Coal storage hopper with vibrating-screen agitator  

DOE Patents (OSTI)

The present invention is directed to a vibrating screen agitator in a coal storage hopper for assuring the uniform feed of coal having sufficient moisture content to effect agglomeration and bridging thereof in the coal hopper from the latter onto a conveyer mechanism. The vibrating scrren agitator is provided by a plurality of transversely oriented and vertically spaced apart screens in the storage hopper with a plurality of vertically oriented rods attached to the screens. The rods are vibrated to effect the vibration of the screens and the breaking up of agglomerates in the coal which might impede the uniform flow of the coal from the hopper onto a conveyer.

Daw, C.S.; Lackey, M.E.; Sy, R.L.

1982-04-27T23:59:59.000Z

371

Free film screening at Bradbury Science Museum September 7  

NLE Websites -- All DOE Office Websites (Extended Search)

Free Film Screening At Bradbury Science Museum Community Connections: Our link to Northern New Mexico Communities Latest Issue:Dec. 2013 - Jan. 2014 All Issues submit Free film...

372

Former Worker Medical Screening Program - Argonne National Laboratory...  

NLE Websites -- All DOE Office Websites (Extended Search)

Supplemental Screening Program. ORAU has teamed with its partners, Comprehensive Health Services, National Jewish Health, the University of Colorado Denver, and Axion Health,...

373

Former Worker Medical Screening Program - Princeton Plasma Physics...  

NLE Websites -- All DOE Office Websites (Extended Search)

Supplemental Screening Program. ORAU has teamed with its partners, Comprehensive Health Services, National Jewish Health, the University of Colorado Denver, and Axion Health,...

374

Implications of Cost Effectiveness Screening Practices in a Low...  

NLE Websites -- All DOE Office Websites (Extended Search)

Implications of Cost Effectiveness Screening Practices in a Low Natural Gas Price Environment: Case Study of a Midwestern Residential Energy Upgrade Program NOTICE Due to the...

375

A Basic Overview of the Former Worker Medical Screening Program...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

to the privacy rights, the rights and welfare of any participant in former worker medical screening or research performed under DOE authorities is of prime importance to...

376

Virtual Screening of Materials for Gaseous Fuel Storage  

Science Conference Proceedings (OSTI)

Presentation Title, Virtual Screening of Materials for Gaseous Fuel Storage .... Numerical Study on Behavior of Top-Blown Supersonic Jets and Their Interaction ...

377

2012 Former Worker Medical Screening Program Annual Report  

Energy.gov (U.S. Department of Energy (DOE))

The 2012 Annual Report presents a detailed overview of the accomplishments, progress, and future endeavors of the U.S. Department of Energy Former Worker Medical Screening Program.

378

Former Worker Medical Screening Program - Iowa Army Ammunition...  

NLE Websites -- All DOE Office Websites (Extended Search)

Former Worker Medical Screening Program (FWP) Project Name: Medical Monitoring of Former Atomic Weapons Workers at the Iowa Army Ammunition Plant (IAAP) in Burlington, Iowa...

379

Method of Rapidly Screening Buffer Layers in Photovoltaics  

ORNL 2010-G0647/jcn UT-B ID 200902275 Method of Rapidly Screening Buffer Layers in Photovoltaics Technology Summary This ORNL invention offers a new method to ...

380

SUPPLEMENTAL GUIDANCE FOR DEVELOPING SOIL SCREENING LEVELS FOR...  

NLE Websites -- All DOE Office Websites (Extended Search)

Solid Waste and Environmental Protection Emergency Response December 2002 Agency OSWER 9355.4-24 Superfund SUPPLEMENTAL GUIDANCE FOR DEVELOPING SOIL SCREENING LEVELS FOR SUPERFUND...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Former Worker Medical Screening Program - Ames Laboratory Former...  

NLE Websites -- All DOE Office Websites (Extended Search)

Ames Laboratory Former Workers Former Worker Medical Screening Program (FWP) Project Name: Medical Monitoring of Former Workers at the Ames National Laboratory Covered DOE Site:...

382

Laboratory Evaluation of the Beaudrey Water Intake Protection Screen for Protecting Early Life Stages of Fish at Cooling Water Intak e Structures  

Science Conference Proceedings (OSTI)

This report presents the final results of laboratory evaluations on the performance of a fine-mesh (2.0 mm) water intake protection (WIP) screen manufactured by Beaudrey to protect larval and early juvenile fish at cooling water intake structures (CWISs). This screening technology relies on the use of a vacuum system to collect organisms from the surface of the screen and transport them to a fish return system. This is the first study to investigate the survival of larval and early juvenile fish that hav...

2011-05-09T23:59:59.000Z

383

Medical Screening Protocol for the Former Worker Medical Screening Program U.S. Department of Energy, April 16, 2013  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

4/16/13 4/16/13 MEDICAL SCREENING PROTOCOL FOR THE FORMER WORKER MEDICAL SCREENING PROGRAM U.S. DEPARTMENT OF ENERGY General Principles: 1) The purpose of the medical evaluation component of the U.S. Department of Energy (DOE) Former Worker Medical Screening Program (FWP) is to provide interested former workers with targeted testing to screen for selected adverse health effects potentially related to their work in DOE operations. The program does not test for all potentially work-related conditions; for example, screening for work- related musculoskeletal conditions is not included in the medical evaluation. 2) The following table is intended to identify work-related health outcomes of relevance to DOE workers for which there are screening tests that are reasonably likely to be effective and beneficial to program

384

Medical Screening Protocol for the Former Worker Medical Screening Program U.S. Department of Energy, April 16, 2013  

NLE Websites -- All DOE Office Websites (Extended Search)

4/16/13 4/16/13 MEDICAL SCREENING PROTOCOL FOR THE FORMER WORKER MEDICAL SCREENING PROGRAM U.S. DEPARTMENT OF ENERGY General Principles: 1) The purpose of the medical evaluation component of the U.S. Department of Energy (DOE) Former Worker Medical Screening Program (FWP) is to provide interested former workers with targeted testing to screen for selected adverse health effects potentially related to their work in DOE operations. The program does not test for all potentially work-related conditions; for example, screening for work- related musculoskeletal conditions is not included in the medical evaluation. 2) The following table is intended to identify work-related health outcomes of relevance to DOE workers for which there are screening tests that are reasonably likely to be effective and beneficial to program

385

Apparatus and method for radioactive waste screening  

DOE Patents (OSTI)

An apparatus and method relating to screening radioactive waste are disclosed for ensuring that at least one calculated parameter for the measurement data of a sample falls within a range between an upper limit and a lower limit prior to the sample being packaged for disposal. The apparatus includes a radiation detector configured for detecting radioactivity and radionuclide content of the of the sample of radioactive waste and generating measurement data in response thereto, and a collimator including at least one aperture to direct a field of view of the radiation detector. The method includes measuring a radioactive content of a sample, and calculating one or more parameters from the radioactive content of the sample.

Akers, Douglas W.; Roybal, Lyle G.; Salomon, Hopi; Williams, Charles Leroy

2012-09-04T23:59:59.000Z

386

Reservoir screening criteria for underbalanced drilling  

Science Conference Proceedings (OSTI)

Properly designed and executed underbalanced drilling operations can eliminate or significantly reduce formation damage, mud or drill solids invasion, lost circulation, fluid entrainment and trapping effects, and potential adverse reactions of drilling fluids with the reservoir matrix or in-situ reservoir fluids. The key to selecting appropriate reservoir candidates is achieving a balance of technical, safety and economic factors. Not every reservoir is an ideal candidate for an underbalanced drilling operation and in some cases distinct disadvantages may exist in trying to execute an underbalanced drilling operation in comparison to a simpler more conventional overbalanced application. Extensive field experience has played an important role in determining the following key criteria and design considerations that should be examined when evaluating a well. Screening criteria are also provided to help operators ascertain if a given formation is, in fact, a viable underbalanced drilling candidate.

Bennion, D.B. [Hycal Energy Research Labs. Ltd., Calgary, Alberta (Canada)

1997-02-01T23:59:59.000Z

387

STATEMENT OF CONSIDERATIONS REQUEST BY A123 SYSTEMS, INC. FOR AN ADVANCE WAIVER OF DOMESTIC AND  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

1187, W(A)-2011-038, CH-1616 1187, W(A)-2011-038, CH-1616 The Petitioner, A123 Systems, Inc (A123) was awarded this cooperative agreement for the performance of work entitled, "High Throughput Fabrication of 10-Year PHEV Battery Electrodes". The purpose of the agreement is to develop advanced manufacturing technology for high-energy lithium ion batteries suitable for PHEV applications. This effort focuses speCifically on several unit operations used in electrode fabrication. By increasing the solids loading and stability of electrode slurry of the fabrication process, the electrode cost will be reduced through the decrease of drying time and the elimination of solvent emissions. Controlling the moisture content will primarily benefit electrode cycle life. Increasing the throughput of the coating/drying operation, this objective will

388

Former Worker Medical Screening Program 2012 Annual Report  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Published February 2013 Published February 2013 Pu Pu Publ b blis s ishe he hed d d Fe Fe Febr br brua ua u ry ry 2 201 013 3 FORMER WORKER MEDICAL SCREENING PROGRAM ANNUAL REPORT ANNUAL REPORT 2 0 1 2 STC STONETURN CONSULTANTS 2012 Former Worker Medical Screening Program * i Table of Contents Abbreviations ............................................................................................................................................iii Foreword .................................................................................................................................................... v Executive Summary .................................................................................................................................

389

A pilot study of four cultural touch-screen games  

Science Conference Proceedings (OSTI)

Four simple single-player games (based on the "Four Arts" of traditional Chinese culture) have been designed in Flash for a touch-screen display. The aim is to allow players to experience a digital interactive recreation of traditional Chinese culture, ... Keywords: Chinese, Daoism, Flash, Four Arts, calligraphy, cultural heritage, go, interactive games, music, touch screen

Li Wang; Erik Champion

2011-07-01T23:59:59.000Z

390

Screening criteria help select formations for underbalanced drilling  

Science Conference Proceedings (OSTI)

Certain laboratory screening procedures can help determine the effectiveness of underbalanced drilling in a specific application. These screening criteria can help in analyzing the types of reservoirs which present good applications for underbalanced drilling technology. This paper discusses the types of information that should be obtained for any reservoir prior to designing the underbalanced drilling program for optimum performance.

Bennion, D.B. [Hycal Energy Research Labs. Ltd., Calgary, Alberta (Canada)

1996-01-08T23:59:59.000Z

391

Rocky Flats Former Construction Workers, Construction Worker Screening  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Rocky Flats Former Construction Workers, Construction Worker Rocky Flats Former Construction Workers, Construction Worker Screening Projects Rocky Flats Former Construction Workers, Construction Worker Screening Projects Project Name: Building Trades National Medical Screening Program Covered DOE Site: Rocky Flats Worker Population Served: Construction Workers Principal Investigator: Knut Ringen, DrPH, MHA, MPH Toll-free Telephone: (800) 866-9663 Local Outreach Office: Dwayne Adkins 7510 W. Mississippi Ave., Suite 230 Lakewood, CO 80226 Website: http://www.btmed.org This project is intended to provide free medical screening to former workers in the building trades (construction workers). The screening targets health problems resulting from exposures, including asbestos, beryllium, cadmium, chromium, lead, mercury, noise, radiation, silica

392

Former Worker Medical Screening Program | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Former Worker Medical Screening Former Worker Medical Screening Program Former Worker Medical Screening Program The Former Worker Medical Screening Program (FWP) provides ongoing medical screening examinations, at no cost, to all former DOE Federal, contractor, and subcontractor workers who may be at risk for occupational diseases. The FWP is supported by the U.S. Department of Energy's (DOE) Office of Health, Safety and Security (HSS) and reflects our commitment to the health and safety of all DOE workers - past and present - who have served the Nation in its National security and other missions. The FWP was established following the issuance of the National Defense Authorization Act for Fiscal Year 1993 (PL 102-484), which called for DOE to assist workers with determining whether they had health issues related

393

One piece microwave container screens for electrodeless lamps  

DOE Patents (OSTI)

A microwave powered electrodeless lamp includes an improved screen unit having mesh and solid sections with an internal reflector to reflect light into a light-transmitting chamber defined in the lamp microwave cavity by the reflector and the mesh section. A discharge envelope of a bulb is disposed in the light-transmitting chamber. Light emitted from the envelope is prevented by the reflector from entering the cavity portion bounded by the solid section of the screen. Replacing mesh material by solid metal material as part of the screen unit significantly reduces leakage of microwave energy from the lamp. The solid section has multiple compliant fingers defined therein for engaging the periphery of a flange on the waveguide unit so that a hose clamp can easily secure the screen to the assembly. Screen units of this type having different mesh section configurations can be interchanged in the lamp assembly to produce different respective illumination patterns.

Turner, Brian (Myersville, MD); Ury, Michael (Bethesda, MD)

1998-01-01T23:59:59.000Z

394

High-Solids Enzymatic Saccharification Screening Method for Lignocellulosic Biomass (Poster)  

DOE Green Energy (OSTI)

The ability to screen new biomass pretreatments and advanced enzyme systems at process-relevant conditions is key to developing economically viable lignocellulosic ethanol. While much research is being invested in developing pretreatment technologies and enzyme systems that will more efficiently convert cellulosic biomass to sugars, the current standard reactor vessel, a shake flask, that is used for screening enzymatic saccharification of cellulosic biomass is inadequate at high-solids conditions. Shake flasks do not provide adequate mixing at high solids conditions. In this work, a roller bottle reactor was identified as a small-scale high-solids saccharification reaction vessel, and a method was developed for use in screening both pretreated biomass and enzyme systems at process-relevant conditions. This new method addresses mixing issues observed in high-solids saccharifications. In addition, yield calculations from sugar concentrations on a mass basis were used to account for the two-phase nature of the saccharification slurry, which eliminates discontinuities in comparing high-solids to low-solids saccharifications that occur when using concentrations on a volume basis. The roller bottle reactors out-performed the shake flasks by 5% for an initial insoluble solids loading of 15% and 140% for an initial soluble solids loading of 30%. The reactor system and method was compared at bench and floor scales and determined to be scalable for initial insoluble solids loading in the range of 15% to 30%. Pretreatment and enzyme screening results indicate that mid severity pretreated biomass is more digestible than the low and high severity biomass and GC220 is a superior enzyme to Spezyme CP.

Roche, C. M.; Stickel, J. J.

2009-05-01T23:59:59.000Z

395

Systems  

E-Print Network (OSTI)

Abstract Developing usable and robust mixed reality systems requires unique humancomputer interaction techniques and customized hardware systems. The design of the hardware is directed by the requirements of the rich 3D interactions that can be performed using immersive mobile MR systems. Geometry modeling and capture, navigational annotations, visualizations, and training simulations are all enhanced using augmented computer graphics. We present the design guidelines that have led us through 10 years of evolving mobile outdoor MR hardware systems.

Benjamin Avery; Ross T. Smith; Wayne Piekarski; Bruce H. Thomas

2009-01-01T23:59:59.000Z

396

Federal Renewable Energy Screening Assistant User's Manual  

Science Conference Proceedings (OSTI)

The FRESA computer program, Version 2.1 provides an easy way to collect and process building and facility data to indicate opportunities for renewable energy applications in federal facilities and buildings. The purpose of this analytic tool is to focus feasibility study efforts on those applications most likely to prove cost-effective. The program is a supplement to energy and water conservation audits, which must be completed for all federal buildings and will flag renewable energy opportunities by facilitating the evaluation and ranking process. FRESA results alone are generally not sufficient to establish project feasibility. Software location: http://www.eren.doe.gov/femp/techassist/softwaretools/softwaretools.html. The FRESA User's Manual provides instruction on getting started; an overview of the FRESA program structure; an explanation of the screening process; detailed information on using the functions of Facility/Building Info, Building/Facility Analysis, Input/Output, and We ather Data or Adding a Zip Code; troubleshooting, and archiving data. Appendices include Algorithms Used in FRESA Prescreening, Excel Spread sheets for FRESA Inputs, Other Useful Information, and Acronyms and Abbreviations.

Brown, T.; Tapia, D.; Mas, C.

1999-05-17T23:59:59.000Z

397

Screening criteria for microbial for processes  

SciTech Connect

The National Institute for Petroleum and Energy Research (NIPER) has maintained a microbial enhanced oil recovery (MEOR) field project data base since 1985. One of the major goals of this data base is to continue to document characteristics of reservoirs used for MEOR field projects and to assist the US Department of Energy by revising published screening criteria for MEOR processes. Since the last update of this data base in 1987, the number of MEOR field projects entered has increased from 39 to 65. Microbial EOR has been recognized as a potentially cost-effective method, particularly for stripper well production. Stripper wells are particularly in need of cost-effective EOR because independent operators produce about 40% of the total oil recovered, but cannot conduct needed EOR research. Microbial methods for improving oil recovery are potentially cost-effective and particularly well suited to be applied in today's economic climate. The lower price of crude oil as well as a more general acceptance of use of biotechnological processes has probably contributed to this increase. Although in some instances information was unavailable or not reported for each element of the data base, there exists adequate data to demonstrate both the viability and variety of options for using microbial technology for improved oil production. this report updates the data base and provides summary of several of the more important MEOR field experiments conducted during the 1970s and 1980s. 19 refs., 1 fig., 11 tabs.

Bryant, R.S.

1990-12-01T23:59:59.000Z

398

FEPs Screening of Processes and Issues in Drip Shield and Waste Package Degradation  

Science Conference Proceedings (OSTI)

The purpose of this report is to evaluate and document the inclusion or exclusion of features, events and processes (FEPs) with respect to drip shield and waste package modeling used to support the Total System Performance Assessment for License Application (TSPA-LA). Thirty-three FEPs associated with the waste package and drip shield performance have been identified (DTN: MO0407SEPFEPLA.000 [DIRS 170760]). A screening decision, either ''included'' or ''excluded,'' has been assigned to each FEP, with the technical bases for screening decisions, as required by the Nuclear Regulatory Commission (NRC) in 10 CFR 63.114 (d, e, and f) [DIRS 156605]. The FEPs analyses in this report address issues related to the degradation and potential failure of the drip shield and waste package over the post closure regulatory period of 10,000 years after permanent closure. For included FEPs, this report summarizes the disposition of the FEP in TSPA-LA. For excluded FEPs, this report provides the technical bases for the screening arguments for exclusion from TSPA-LA. The analyses are for the TSPA-LA base-case design (BSC 2004 [DIRS 168489]), where a drip shield is placed over the waste package without backfill over the drip shield (BSC 2004 [DIRS 168489]). Each FEP includes one or more specific issues, collectively described by a FEP name and description. The FEP description encompasses a single feature, event, or process, or a few closely related or coupled processes, provided the entire FEP can be addressed by a single specific screening argument or TSPA-LA disposition. The FEPs were assigned to associated Project reports, so the screening decisions reside with the relevant subject-matter experts.

K. Mon

2004-10-11T23:59:59.000Z

399

Human portable preconcentrator system  

DOE Patents (OSTI)

A preconcentrator system and apparatus suited to human portable use wherein sample potentially containing a target chemical substance is drawn into a chamber and through a pervious screen. The screen is adapted to capture target chemicals and then, upon heating, to release those chemicals into the chamber. Chemicals captured and then released in this fashion are then carried to a portable chemical detection device such as a portable ion mobility spectrometer. In the preferred embodiment, the means for drawing sample into the chamber comprises a reversible fan which, when operated in reverse direction, creates a backpressure that facilitates evolution of captured target chemicals into the chamber when the screen is heated.

Linker, Kevin L. (Albuquerque, NM); Bouchier, Francis A. (Albuquerque, NM); Hannum, David W. (Albuquerque, NM); Rhykerd, Jr., Charles L. (Albuquerque, NM)

2003-01-01T23:59:59.000Z

400

How much is a health insurer willing to pay for colorectal cancer screening tests?  

Science Conference Proceedings (OSTI)

Colorectal Cancer (CRC) screening tests have proven to be cost-effective in preventing cancer incidence. Yet, as recent studies have shown, CRC screening tests are noticeably underutilized. Among the factors influencing CRC screening test utilization, ...

Reza Yaesoubi; Stephen D. Roberts

2008-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Glossary of Screen Labels for PARS II V1 | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Glossary of Screen Labels for PARS II V1 Glossary of Screen Labels for PARS II V1 Glossary of Screen Labels for PARS II V1 More Documents & Publications PARS II Standard Operating...

402

Former Worker Medical Screening Program Related Documents & Links |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Former Former Worker Medical Screening Program Related Documents & Links Former Worker Medical Screening Program Related Documents & Links Related Documents & Links Beryllium Information-ORISE Chronic Beryllium Disease Information-National Jewish Health Department of Energy Human Subjects Protection Program DOE Covered Facilities Database Department of Labor Energy Employees Occupational Illness Compensation Program (EEOICP) Department of Labor EEOICP - Upcoming Events Department of Labor Office of the Ombudsman for EEOICPA NIOSH Advisory Board and Public Meetings NIOSH Division of Compensation Analysis and Support Project Websites Building Trades National Medical Screening Program Medical Exam Program for Former Workers at Los Alamos National Laboratory

403

Beryllium Vender Screening Program | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

(Springdale, CT); Gerity-Michigan Corporation (Adrian, MI); Revere Copper and Brass (Detroit, MI); Speedring Systems, Inc. (Detroit, MI); Wolverine Tube Division...

404

Smallscale and automatable highthroughput compositional analysis of biomass  

NLE Websites -- All DOE Office Websites (Extended Search)

Small-Scale Small-Scale and Automatable High-Throughput Compositional Analysis of Biomass Jaclyn D. DeMartini, Michael H. Studer, Charles E. Wyman Center for Environmental Research and Technology, Bourns College of Engineering, University of California Riverside, 1084 Columbia Avenue, Riverside, California 92507; telephone: 951-781-5703; fax: 951-781-5790; e-mail: charles.wyman@ucr.edu Received 26 May 2010; revision received 26 August 2010; accepted 3 September 2010 Published online 9 September 2010 in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/bit.22937 ABSTRACT: Conventional wet chemistry methods to deter- mine biomass composition are labor- and time-intensive and require larger amounts of biomass (300 mg) than is often available. To overcome these limitations and to sup- port a high-throughput pretreatment and hydrolysis (HTPH) screening system,

405

Global health response more accurate with automated influenza surveillance  

NLE Websites -- All DOE Office Websites (Extended Search)

Global health response more accurate with automated influenza Global health response more accurate with automated influenza surveillance Global health response more accurate with automated influenza surveillance Public health officials will be able to determine whether an outbreak of an infectious disease comes from a pandemic strain or one less virulent. January 31, 2011 Lance Green of LANL tests an earlier version of a modular laboratory like the ones that will be part of the High-Throughput Laboratory Network Lance Green of LANL tests an earlier version of a modular laboratory like the ones that will be part of the High-Throughput Laboratory Network-a series of compact, self-contained, automated systems for surveillance and screening of potential pandemic strains of influenza and other deadly infectious diseases.

406

Renewable Energy Resource Maps and Screening Tools | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Resource Maps Resource Maps and Screening Tools Renewable Energy Resource Maps and Screening Tools October 7, 2013 - 9:42am Addthis Renewable energy resources are available across the United States but vary greatly depending on exact location and micro-climate. This page outlines renewable energy resource maps and screening tools to help Federal agencies assess the viability of on-site renewable energy projects. Before initiating a project, resources in your area must be measured and verified. Resource maps and screening tools are a good start, but it is important to consult an expert for a professional evaluation before implementing renewable energy projects. Resource Maps The U.S. Department of Energy (DOE) and its National Renewable Energy Laboratory compiled the following renewable energy resource maps.

407

Outreach (Former Worker Medical Screening Program (FWP) | Department of  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Outreach (Former Worker Medical Screening Program (FWP) Outreach (Former Worker Medical Screening Program (FWP) Outreach (Former Worker Medical Screening Program (FWP) Outreach: Identify and Notify Eligible DOE Workers About FWP Medical Screening Services All former DOE Federal, contractor, and subcontractor employees from all facilities are eligible to participate in the program. Although the historical best estimate for the population of former workers who are entitled to receive medical evaluations under the FWP is upwards of 600,000 individuals, the precise number of workers remains unknown. Most of the FWP projects use multiple outreach methods to increase the visibility of the program in communities surrounding DOE sites and to notify potentially eligible DOE workers about the availability of FWP services. These methods are three-fold: 1) roster-based, 2)

408

Pantex, Former Production Workers Screening Projects | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Pantex, Former Production Workers Screening Projects Pantex, Former Production Workers Screening Projects Pantex, Former Production Workers Screening Projects Project Name: Former Pantex Worker Medical Surveillance Program Covered DOE Site: Pantex Worker Population Served: All Workers Principal Investigator: Arthur Frank, MD, MPH Toll-free Telephone: (888) 378-8939 Local Medical Clinics: WTAMU Health Partners Clinic 4400 S. Washington Street Amarillo, TX 79110 Texas Diagnostic Imaging Center (X-rays only) 1000 Coulter Drive Amarillo, TX 79106 Former workers at risk from exposures while working at Pantex are offered a free medical screening. This project is carried out by Drexel University School of Public Health in conjunction with the University of Texas Health Science Center at Tyler. Workers from this site who do not live in close proximity to the above

409

Iowa Army Ammunition Plant, Former Production Workers Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Plant, Former Production Workers Screening Plant, Former Production Workers Screening Projects Iowa Army Ammunition Plant, Former Production Workers Screening Projects Project Name: Medical Monitoring of Former Atomic Weapons Workers at the Iowa Army Ammunition Plant (IAAP) in Burlington, Iowa Covered DOE Site: IAAP Worker Population Served: All Line 1/Division B Workers Principal Investigator: Laurence Fuortes, MD Toll-free Telephone: (866) 282-5818 Local Medical Clinics: University of Iowa Hospitals and Clinics 200 Hawkins Drive Iowa City, IA 52242 Henry County Health Center 407 South White Street Mt. Pleasant, IA 62641 Great River Medical Center 1221 S. Gear Avenue West Burlington, IA 52655 Website: http://cph.uiowa.edu/iowafwp/ This project is intended to screen for occupational health conditions among

410

Magnetic and electric screening masses from Polyakov-loop correlations  

E-Print Network (OSTI)

Screening properties of the quark gluon plasma are studied from Polyakov-loop correlation in lattice QCD simulations with two flavors of improved Wilson quarks at temperatures $T/\\Tpc \\simeq 1$--4 where $\\Tpc$ is the pseudocritical temperature. Using the Euclidean-time reflection symmetry and the charge conjugation symmetry, we introduce various types of Polyakov-loop correlation functions and extract screening masses in magnetic and electric sectors. We find that the temperature dependence of the screening masses are well described by the weak coupling expansion. We also find that a ratio of the screening masses in the electric sector to the magnetic sector shows qualitative agreement with a prediction from the dimensionally-reduced effective field theory and the N=4 supersymmetric Yang-Mills theory at $1.3 < T/\\Tpc < 3$.

Y. Maezawa; S. Aoki; S. Ejiri; T. Hatsuda; N. Ishii; K. Kanaya; N. Ukita; T. Umeda

2008-11-04T23:59:59.000Z

411

Automatic Misregistration Testing Apparatus for Line Screen Color CRT'S  

Science Conference Proceedings (OSTI)

Optimum color CRT performance requires that the electron beam impinge on the screen at the proper phosphor stripe. The extent to which the beam fails to strike the intended phosphor stripe is referred to as misregistration. Misregistration leads to loss ...

Allan D. Kautz

1983-08-01T23:59:59.000Z

412

Stochastic dominance for project screening and selection under uncertainty  

E-Print Network (OSTI)

At any given moment, engineering and chemical companies have a host of projects that they are either trying to screen to advance to the next stage of research or select from for implementation. These choices could range ...

Adeyemo, Adekunle M

2013-01-01T23:59:59.000Z

413

NETL: News Release - NETL Receives Blue Pencil and Gold Screen...  

NLE Websites -- All DOE Office Websites (Extended Search)

The honor was awarded at the NAGC Blue Pencil and Gold Screen Awards Reception and Banquet on Monday, May 17,2010, in Bethesda, Md., during the 2010 NAGC Communications School....

414

Bush Administration to Expand Beryllium Disease Screening Program  

Energy.gov (U.S. Department of Energy (DOE))

WASHINGTON, DC U.S. Secretary of Energy Samuel W. Bodman today announced the Department of Energy (DOE) will expand a beryllium screening program to include former employees of now-defunct DOE...

415

John Day Fish Passage and Screening; 2003 Annual Report.  

DOE Green Energy (OSTI)

The primary goal of the Oregon Screens Project was to implement 20 replacement screens projects in the John Day sub-basin and any projects identified in the Umatilla and Walla Walla sub-basins. A secondary goal is to complete a passage project, if one is identified, in any of the above sub-basins. Mid-Columbia ESU listed steelhead and USF&W listed bull trout inhabit these sub-basins and are present at most locations, along with a variety of resident fish species. We also provide assistance to our Enterprise Screen Shop, in the Grande Ronde/Imnaha sub-basins, if needed. All projects were designed and implemented under current National Marine Fisheries Service screening and passage criteria.

Allen, Steve (Oregon Department of Fish and Wildlife, John Day, OR)

2004-02-01T23:59:59.000Z

416

John Day Fish Passage and Screening; 2004 Annual Report.  

DOE Green Energy (OSTI)

The primary goal of the Oregon Screens Project was to implement 20 replacement screens projects in the John Day sub-basin and any projects identified in the Umatilla and Walla Walla sub-basins. A secondary goal is to complete a passage project, if one is identified, in any of the above sub-basins. Mid-Columbia ESU listed steelhead and USF&W listed bull trout inhabit these sub-basins and are present at most locations, along with a variety of resident fish species. We also provide assistance to our Enterprise Screen Shop, in the Grande Ronde/Imnaha subbasins, if needed. All projects were designed and implemented under current National Marine Fisheries Service screening and passage criteria.

Allen, Steve (Oregon Department of Fish and Wildlife, John Day, OR)

2005-02-01T23:59:59.000Z

417

Improved screen-bowl centrifuge recovery using polymer injection technology  

Science Conference Proceedings (OSTI)

The paper reports the improved screen-bowl centrifuge recovery process using polymer injection technology. Field test and economic analysis are also included in the paper. 3 refs., 3 figs., 1 tab.

Burchett, R.T.; McGough, K.M.; Luttrell, G.H.

2006-08-15T23:59:59.000Z

418

FREE FILM SCREENING AND DISCUSSION Abstract from Jezebel Productions  

E-Print Network (OSTI)

FREE FILM SCREENING AND DISCUSSION Abstract from Jezebel Productions: "No Dinosaurs in Heaven charge: free and open to the public. THURSDAY OCTOBER 27, 2011 7:00 PM Mackey Auditorium Ruby Gerontology

de Lijser, Peter

419

Screening China : China in popular geopolitics, 2000-2009.  

E-Print Network (OSTI)

??Looking at global box-office winners from the years 2000-2009, this paper finds that the China we encounter on the silver screen, is rarely an antagonist. (more)

Braastad, J. Steffen

2010-01-01T23:59:59.000Z

420

Combinatorial screening for the identification of Mg-based destabilize...  

NLE Websites -- All DOE Office Websites (Extended Search)

Combinatorial screening for the identification of Mg-based destabilized hydrogen storage materials Speaker(s): Robin Gremaud Date: October 16, 2006 - 12:00pm Location: 90-3122...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

www.mdpi.com/journal/jlpea/ Multi-Functional Micro Projection Device as Screen Substitute for Low Power Consumption Computing  

E-Print Network (OSTI)

Abstract: One of the major power consuming components in a computer is its display unit. On average the screen consumes ten times more power than the DSP processor itself. Thus, reducing the power consumption should be one of the most important tasks in the development of low power consumption computing systems. In this paper we present one possible solution involving micro projection device based upon lasers and a digital light processing (DLP) matrix which is a matrix of electrically controllable mirrors capable of translating electrical signal to a time varying projected image. It can serve to substitute a screen and consume ten times less power than a conventional screen. The described device is a multifunctional highly efficient customized DLP light engine being capable of serving as an image projector and simultaneously to support range and topography estimation measurements.

Low Power Electronics; Yuval Kapellner; Zeev Zalevsky

2012-01-01T23:59:59.000Z

422

AVIAN AND BAT SCREENING ANALYSIS AND HABITAT CHARACTERIZATION  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

AVIAN AND BAT SCREENING ANALYSIS AVIAN AND BAT SCREENING ANALYSIS AND HABITAT CHARACTERIZATION Barr Engineering Company UMore Park Research Wind Turbine Dakota County, Minnesota June 2010 Prepared For: Barr Engineering Company 4700 West 77 th St. Minneapolis, MN 55435 Prepared By: 1900 Wazee Street, Suite 200 Denver, Colorado 80202 Phone: (720) 330-7280 Fax: (303) 458-5701 www.nrcdifference.com NRC Project # 0010-0110-01

423

Pacific Northwest Laboratory`s Lighting Technology Screening Matrix  

SciTech Connect

Pacific Northwest Laboratory has developed the Lighting Technology Screening Matrix (LTSM), a software tool to evaluate alternative lighting retrofit technologies according to life-cycle cost. The LTSM can be used to evaluate retrofits for most configurations of fluorescent, incandescent, high- and low-pressure sodium, metal halide, mercury vapor, and exit lighting systems for any level of operation, electricity price, discount rate, and utility rebate. This tool was developed, in support of the Federal Relighting Initiative as part of the Department of Energy`s Office of Federal Energy Management Program (DOE/FEMP) to assist federal government facilities in their efforts to comply with the 10 CFR 436 mandated life-cycle costing for energy equipment investments. The LTSM has been used in the course of seven site modernization projects. These projects consisted of determining the cost-effective, energy-efficiency potential at military installations. Each project treated the entire military installation as an integrated system, proposed a large number of potential efficiency projects affecting all end-uses and fuel types, and analyzed the cost-effectiveness of each project. The LTSM was used for the lighting portion of these projects. Lighting was, overall, one of the major areas of potential efficiency improvements, accounting for over 30% of the cost-effective resource. Altogether over $43 million worth of cost-effective efficiency investments were identified, worth an estimated $6 million annually in energy, demand, and operations and maintenance (O&M) savings. This paper describes the LTSM and demonstrates its application in a case study at one of the federal installations analyzed.

Harris, L.R. [USDOE, Washington, DC (United States); Stucky, D.J.; Dirks, J.A.; Schultz, R.W.; Shankle, S.A.; Richman, E.E.; Purcell, C.W. [Pacific Northwest Lab., Richland, WA (United States)

1994-04-01T23:59:59.000Z

424

Conservation screening curves to compare efficiency investments to power plants  

SciTech Connect

This paper describes a simplified methodology to compare supply and demand-side resources. The screening curve approach supplements with load shape information the data contained in a supply curve of conserved energy. In addition, a screening curve contains information on competing supply technologies, such as annualized capital costs, variable costs, and cost per delivered kWh. The information in the screening curve allows policymakers to promptly and conveniently compare the relevant parameters affecting supply and demand-side investment decisions. While many sophisticated computer models have evolved to account for the load shape impacts of energy efficiency investments, this sophistication has, by and large, not trickled down to spreadsheet-level or back-of-the-envelope analyses. This methodology allows a simple summary of load shape characteristics based on the output of the more complicated models. It offers many advantages, principal of which is clarity in analyzing supply and demand-side investment choices. This paper first describes how supply-side screening curves have been used in the past, and develops the conceptual tools needed to apply integrated supply/demand screening curves in the least-cost utility planning process. It then presents examples of supply and demand-side technologies and plots them on a representative screening curve. 12 refs., 3 figs., 3 tabs.

Koomey, J.; Rosenfeld, A.H.; Gadgil, A.

1989-10-01T23:59:59.000Z

425

Movement of Fall Chinook Salmon Fry Oncorhynchus Tshawytscha : A Comparison of Approach Angles for Fish Bypass in a Modular Rotary Drum Fish Screen.  

DOE Green Energy (OSTI)

The Pacific Northwest National Laboratory (PNNL) performed tests to determine whether a significant difference in fish passage existed between a 6-ft screening facility built perpendicularly to canal flow and an identical screening facility with the screen mounted at a 45-degree angle to the approach channel. A modular drum screen built by the Washington Department of Fish and Wildlife was installed at PNNL`s Aquatic Ecology research laboratory in Richland, Washington. Fall chinook salmon fry were introduced into the test system, and their movements were monitored. A total of 14 tests (400 fish per test) that lasted 20 hours were completed during April and May, 1996. There was no significant difference in fish passage rate through the two approach configurations. Attraction flow to the bypass across the face of the screen was more evident for the angled approach, although this did not appear to play a significant role in attracting fish to the bypass. Approach velocities at the face of the screen did not exceed the 0.4 fps criteria for either approach configuration and posed not threat to fish. No fish passed over, around, or through the drum screen during any test.

Neitzel, D.A.; Blanton, S.L.; Abernethy, C. Scott; Daly, D.S. [Pacific Northwest National Laboratory, Richland, WA (United States)

1996-08-01T23:59:59.000Z

426

HVAC Chiller Plant Screening Case Studies  

Science Conference Proceedings (OSTI)

EPRI's ChillerCalc software program is a useful tool for analyzing first-order comparative studies of chiller plant energy use, environmental performance, and economics. Hybrid cooling systems, which combine gas-fired and electric-driven chilling equipment, are emerging as a strategy to reduce central plant-related energy and demand costs. Although originally designed to analyze one-fuel type chillers at a time, ChillerCalc's capabilities were stretched to analyze hybrid systems. This report details the ...

2000-12-14T23:59:59.000Z

427

New Paradigm for Macromolecular Crystallography Experiments at SSRL: Automated Crystal Screening And Remote Data Collection  

Science Conference Proceedings (OSTI)

Complete automation of the macromolecular crystallography experiment has been achieved at Stanford Synchrotron Radiation Lightsource (SSRL) through the combination of robust mechanized experimental hardware and a flexible control system with an intuitive user interface. These highly reliable systems have enabled crystallography experiments to be carried out from the researchers' home institutions and other remote locations while retaining complete control over even the most challenging systems. A breakthrough component of the system, the Stanford Auto-Mounter (SAM), has enabled the efficient mounting of cryocooled samples without human intervention. Taking advantage of this automation, researchers have successfully screened more than 200 000 samples to select the crystals with the best diffraction quality for data collection as well as to determine optimal crystallization and cryocooling conditions. These systems, which have been deployed on all SSRL macromolecular crystallography beamlines and several beamlines worldwide, are used by more than 80 research groups in remote locations, establishing a new paradigm for macromolecular crystallography experimentation.

Soltis, S.M.; Cohen, A.E.; Deacon, A.; Eriksson, T.; Gonzalez, A.; McPhillips, S.; Chui, H.; Dunten, P.; Hollenbeck, M.; Mathews, I.; Miller, M.; Moorhead, P.; Phizackerley, R.P.; Smith, C.; Song, J.; Bedem, H.van dem; Ellis, P.; Kuhn, P.; McPhillips, T.; Sauter, N.; Sharp, K.

2009-05-26T23:59:59.000Z

428

NREL: Hydrogen and Fuel Cells Research - Fuel Cell System Contaminants...  

NLE Websites -- All DOE Office Websites (Extended Search)

Fuel Cell System Contaminants Material Screening Data NREL designed this interactive material selector tool to help fuel cell developers and material suppliers explore the results...

429

Development of new tools and applications for high-throughput sequencing of microbiomes in environmental or clinical samples  

E-Print Network (OSTI)

Novel sequencing technologies are rapidly advancing studies of microbial community structure and diversity. Sequencing platforms like the Illumina Genome Analyzer II (GAI1) and the Applied Biosystems SOLiD enable experiments ...

Blackburn, Matthew Christopher

2010-01-01T23:59:59.000Z

430

Methods and devices for fabricating and assembling DNA and protein arrays for high-throughput analyses [electronic resource] /  

E-Print Network (OSTI)

between the glass slide and top block to create leak-freebetween the glass slide and the polycarbonate block usingpolycarbonate block with fluidic ports; b) glass slide with

Barbee, Kristopher David

2010-01-01T23:59:59.000Z

431

Wide-scale population genomics of Atlantic bluefin tuna (Thunnus thynnus) inferred by novel high-throughput technology.  

E-Print Network (OSTI)

??My PhD project was focused on Atlantic bluefin tuna, Thunnus thynnus, a fishery resource overexploited in the last decades. For a better management of stocks, (more)

Pintus, Eleonora and#60;1980and#62

2013-01-01T23:59:59.000Z

432

PHYSICAL REVIEW B 84, 214110 (2011) Ordered phases in ruthenium binary alloys from high-throughput first-principles calculations  

E-Print Network (OSTI)

JAHN ´ATEK et al. PHYSICAL REVIEW B 84, 214110 (2011) and Monte Carlo simulation. Using these methods. Benarchid, N. David, J. M. Fiorani, M. Vilasi, and T. Benlaharche, Thermochim. Acta 482, 39 (2009). 50 A. A¨uller, Modell. Simul. Mater. Sci. Eng. 17, 055003 (2009). 113 A. van de Walle and G. Ceder, Rev. Mod. Phys. 74

Curtarolo, Stefano

433

'Sifting the significance from the data' - the impact of high-throughput genomic technologies on human genetics and health care  

E-Print Network (OSTI)

be particularly high for common diseases. Mapping the polygenes Krawczak also discussed the limitations of the available strategies for mapping the loci which contribute to the common, complex disorders. The power of the affected sib pair (ASP) linkage approach... , Latimer C, Dicks E, Menzies A, Stephens P, Blow M, Greenman C, Xue Y, Tyler- Smith C, Thompson D, Gray K, Andrews J, Barthorpe S, Buck G, Cole J, Dunmore R, Jones D, Maddison M, Mironenko T, Turner R, Turrell K, Varian J, West S, Widaa S, et al: A...

Clarke, Angus J; Cooper, David N; Krawczak, Michael; Tyler-Smith, Chris; Wallace, Helen M; Wilkie, Andrew O M; Raymond, Frances L; Chadwick, Ruth; Craddock, Nick; John, Ros; Gallacher, John; Chiano, Mathias

2012-08-02T23:59:59.000Z

434

Methods and devices for fabricating and assembling DNA and protein arrays for high-throughput analyses [electronic resource] /  

E-Print Network (OSTI)

Y.J. , Chen, Z. et al. Genome sequencing in microfabricatedal. Accurate whole human genome sequencing using reversibleY.J. , Chen, Z. et al. Genome sequencing in microfabricated

Barbee, Kristopher David

2010-01-01T23:59:59.000Z

435

BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data  

E-Print Network (OSTI)

DNA copy number alterations (CNA), which are amplifications and deletions of certain regions in the genome, play an important role in the pathogenesis of cancer and have been shown to be associated with other diseases such ...

Xi, Ruibin

436

Manufacturing improvement and thermal property characterization of the frame structure of an Ultra-high Throughput Mutational Spectrometer  

E-Print Network (OSTI)

Constant denaturant capillary electrophoresis (CDCE) is a DNA separation technique that allows the detection of mutants at a fraction of 10???. CDCE uses a region of constant temperature and constant denaturant concentration ...

Lin, Jiengju J. (Jiengju James)

2005-01-01T23:59:59.000Z

437

Methods and devices for fabricating and assembling DNA and protein arrays for high-throughput analyses [electronic resource] /  

E-Print Network (OSTI)

J. Anodic corrosion of indium tin oxide films induced by thecoverslip coated with indium-tin oxide, which serves as thecoverslip coated with indium-tin oxide (ITO), which serves

Barbee, Kristopher David

2010-01-01T23:59:59.000Z

438

Development of High-Throughput and Real-Time Methods for the Detection of Infectious Enteric Viruses  

E-Print Network (OSTI)

Melvin. 2005. Quenching of CdSe quantum dot emission, a new2000. Self-assembly of CdSe-ZnS quantum dot bioconjugates2000. Self-assembly of CdSe-ZnS quantum dot bioconjugates

YEH, HSIAO-YUN

2010-01-01T23:59:59.000Z

439

High Throughput, Low Toxic Processing of Very Thin, High Efficiency CIGSS Solar Cells: Final Report, December 2008  

DOE Green Energy (OSTI)

The work carried out during this project presents the use of diethylselenium or other organometallic precursors as low-toxicity alternative selenium sources for preparing a high-quality absorber.

Dhere, N. G.

2009-04-01T23:59:59.000Z

440

Abstract--Most high-throughput experimental results of protein-protein interactions (PPIs) are seemingly inconsistent  

E-Print Network (OSTI)

Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Evaluation of the Industrial Source Complex Screen2 for regulatory purposes  

E-Print Network (OSTI)

Air dispersion modeling is becoming a significant part of the regulatory process in many states. Most states require all new facilities to obtain a permit prior to construction. Part of this permit application is to demonstrate that once the facility is in operation it will be in compliance with air quality standards for all regulated pollutants. Since it is impossible to measure air quality impacts of a future source, air dispersion modeling is used. In addition to being used in the initial permitting process, modeling could also be used to determine the impact of sources that wish to amend their abatement system, if this amendment will result in increased emissions. Also, any facility that receives a complaint will be evaluated to determine whether they are in violation of the air quality standards. At this point, the regulator could use air dispersion modeling to determine if the facility is in compliance. For all of these cases, it is essential to have a model that will accurately predict the concentration of pollutants downwind from the source. One particular model being used for this purpose is the Industrial Source Complex (ISC) Screen2. However, the use of Screen2 results in inaccurate predictions of downwind concentrations. Therefore, a model that will accurately predict downwind concentrations when compared to ISC Screen2 is sought. This paper will describe a dispersion model that more accurately predicts downwind concentrations of particulate from agricultural operations. Both ISC Screen2 and the proposed model, Classical Gaussian Dispersion (CGD), are based upon the Gaussian diffusion equations.

Williams, Linda Mendez

1996-01-01T23:59:59.000Z

442

Small Distributed Generation Applications in the Industrial Sector: A Screening Assessment  

Science Conference Proceedings (OSTI)

This report documents a screening assessment of small distributed generation applications in the industrial sector.

2001-12-04T23:59:59.000Z

443

Suggested guidelines for anti-islanding screening.  

DOE Green Energy (OSTI)

As increasing numbers of photovoltaic (PV) systems are connected to utility systems, distribution engineers are becoming increasingly concerned about the risk of formation of unintentional islands. Utilities desire to keep their systems secure, while not imposing unreasonable burdens on users wishing to connect PV. However, utility experience with these systems is still relatively sparse, so distribution engineers often are uncertain as to when additional protective measures, such as direct transfer trip, are needed to avoid unintentional island formation. In the absence of such certainty, utilities must err on the side of caution, which in some cases may lead to the unnecessary requirement of additional protection. The purpose of this document is to provide distribution engineers and decision makers with guidance on when additional measures or additional study may be prudent, and also on certain cases in which utilities may allow PV installations to proceed without additional study because the risk of an unintentional island is extremely low. The goal is to reduce the number of cases of unnecessary application of additional protection, while giving utilities a basis on which to request additional study in cases where it is warranted.

Ellis, Abraham; Ropp, Michael

2012-02-01T23:59:59.000Z

444

Yakima River Basin Phase II Fish Screen Evaluations, 2002  

DOE Green Energy (OSTI)

In 2002, the Pacific Northwest National Laboratory evaluated 23 Phase II fish screen sites in the Yakima River Basin as part of a multi-year project for the Bonneville Power Administration on the effectiveness of fish screening devices. Pacific Northwest National Laboratory collected data to determine whether velocities in front of the screens and in the bypasses met National Marine Fisheries Service criteria to promote safe and timely fish passage and whether bypass outfall conditions allowed fish to safely return to the river. In addition, Pacific Northwest National Laboratory conducted underwater video surveys to evaluate the environmental and operational conditions of the screen sites with respect to fish passage. Based on evaluations in 2002, PNNL concluded that: (1) In general, water velocity conditions at the screen sites met fish passage criteria set by the National Marine Fisheries Service. (2) Conditions at most facilities would be expected to provide for safe juvenile fish passage. (3) Conditions at some facilities indicate that operation and/or maintenance should be modified to increase safe juvenile fish passage. (4) Automated cleaning brushes generally functioned properly; chains and other moving parts were typically well greased and operative. (5) Removal of sediment buildup and accumulated leafy and woody debris should be improved at some sites.

Carter, Jessica A.; McMichael, Geoffrey A.; Chamness, Mickie A.

2003-03-01T23:59:59.000Z

445

Yakima River Basin Phase II Fish Screen Evaluations, 2003  

DOE Green Energy (OSTI)

In 2003, the Pacific Northwest National Laboratory (PNNL) evaluated 23 Phase II fish screen sites in the Yakima River Basin as part of a multi-year project for the Bonneville Power Administration on the effectiveness of fish screening devices. PNNL collected data to determine whether velocities in front of the screens and in the bypasses met the Nation Oceanic and Atmospheric Administration Fisheries (NOAA Fisheries, formerly the National Marine Fisheries Service (NMFS)) criteria to promote safe and timely fish passage. In addition, PNNL conducted underwater video surveys to evaluate the environmental and operational conditions of the screen sites with respect to fish passage. Based on evaluations in 2003, PNNL concluded that: (1) In general, water velocity conditions at the screen sites met fish passage criteria set by the National Oceanic and Atmospheric Administration Fisheries. (2) Conditions at most facilities would be expected to provide for safe juvenile fish passage. (3) Conditions at some facilities indicate that operation and/or maintenance should be modified to improve juvenile fish passage conditions. (4) Automated cleaning brushes generally functioned properly; chains and other moving parts were typically well greased and operative. (5) Removal of sediment buildup and accumulated leafy and woody debris could be improved at some sites.

Vucelick, Jessica A.; McMichael, Geoffrey A.; Chamness, Mickie A.

2004-05-01T23:59:59.000Z

446

Paducah Gaseous Diffusion Plant, Production Workers Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Workers Screening Production Workers Screening Projects Paducah Gaseous Diffusion Plant, Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site: Paducah Worker Population Served: Production Workers Principal Investigator: Jim Frederick Co-Principal Investigator: Steven Markowitz, MD Toll-free Telephone: (888) 241-1199 Local Outreach Office: James Harbison 2525 Cairo Road Paducah, KY 42001 Website: http://www.worker-health.org/ This project is conducted by the United Steelworkers in conjunction with Queens College of the City University of New York. The program is being offered as a service to both former and current workers. Free of charge, eligible workers can receive a medical exam, including chest X-ray and breathing test, and an educational workshop. This program also offers CT

447

Laboratory to change vehicle traffic-screening regimen at vehicle  

NLE Websites -- All DOE Office Websites (Extended Search)

Changes to vehicle traffic-screening Changes to vehicle traffic-screening Laboratory to change vehicle traffic-screening regimen at vehicle inspection station Lanes two through five will be open 24 hours a day and won't be staffed by a Laboratory protective force officer. September 1, 2009 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials. Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials.

448

Idaho National Laboratory, Former Production Workers Screening Projects |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Idaho National Laboratory, Former Production Workers Screening Idaho National Laboratory, Former Production Workers Screening Projects Idaho National Laboratory, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site: INL Worker Population Served: Production Workers Principal Investigator: Jim Frederick Co-Principal Investigator: Steven Markowitz, MD Toll-free Telephone: (888) 241-1199 Local Outreach Office: David Fry 1055 Austin Avenue Idaho Falls, ID 83404 Community Care 2725 Channing Way Idaho Falls, ID 83404 Website: http://www.worker-health.org/ This project is conducted by the United Steelworkers, in conjunction with Queens College of the City University of New York. Free of charge, eligible workers can receive a medical exam, including chest X-ray and breathing

449

Beryllium Screening - Informed Choice Document | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Beryllium Screening - Informed Choice Document Beryllium Screening - Informed Choice Document Beryllium Screening - Informed Choice Document January 2007 Cases of chronic beryllium disease (CBD), a legacy of the Department of Energy's (DOE) role in weapons production, have been increasing across the DOE complex. This trend has sparked increased concern about this serious occupational illness. In a national effort to identify current and former workers who have CBD or are sensitized to beryllium and to better understand the illness, DOE has set up a number of medical surveillance and research programs for both current and former workers. The way that workers enroll in the programs and the information that they are given prior to participating in the beryllium lymphocyte proliferation testing (Be-LPT) vary depending on where and when the worker was employed in a DOE

450

Co-benefits Risk Assessment (COBRA) Screening Model | Open Energy  

Open Energy Info (EERE)

Co-benefits Risk Assessment (COBRA) Screening Model Co-benefits Risk Assessment (COBRA) Screening Model Jump to: navigation, search Tool Summary Name: Co-benefits Risk Assessment (COBRA) Screening Model Agency/Company /Organization: United States Environmental Protection Agency Sector: Climate Complexity/Ease of Use: Moderate Website: www.epa.gov/statelocalclimate/resources/cobra.html Cost: Free Related Tools Tool for Selecting CDM Methods & Technologies Modular Applied General Equilibrium Tool (MAGNET) COMMUTER Model ... further results Find Another Tool FIND DEVELOPMENT IMPACTS ASSESSMENT TOOLS Automated tool that can be downloaded from the website. Converts emissions reductions into air quality improvements, estimates annual adverse health impacts avoided, and monetizes the value of these. Approach COBRA converts emissions reductions into air quality improvements, and

451

Fernald, Former Production Workers Screening Projects | Department of  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Workers Screening Projects Production Workers Screening Projects Fernald, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site: Fernald Worker Population Served: Production Workers Principal Investigator: Steven Markowitz, MD Toll-free Telephone: (888) 241-1199 Local Outreach Office Ray Beatty and Mooch Callaway 1150 Harrison Ave., Suite 106 Harrison, OH 45030 Website: http://www.worker-health.org/ This project is being conducted by Queens College of the City University of New York. Free of charge, eligible workers can receive a medical exam, including chest X-ray and breathing test. This program also offers CT scans for early lung cancer detection to workers who have an elevated risk of lung cancer as a result of a combination of occupational exposures, age,

452

Mound, Former Production Workers Screening Projects | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Production Workers Screening Projects Production Workers Screening Projects Mound, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site: Mound Worker Population Served: Production Workers Principal Investigator: Jim Frederick Co-Principal Investigator: Steven Markowitz, MD Toll-free Telephone: 1-877-866-6802 Local Outreach Office Eric Parker, Paige Gibson and Mike Ball 113 East Central Avenue W. Carrollton, OH 45449 Website: http://www.worker-health.org/ This project is being conducted by the United Steelworkers, in conjunction with Queens College of the City University of New York. Free of charge, eligible workers can receive a medical exam, including chest X-ray and breathing test, and an educational workshop. This program also offers CT

453

Project Screening and Design Toolkit | Open Energy Information  

Open Energy Info (EERE)

Screening and Design Toolkit Screening and Design Toolkit (Redirected from Gateway:International/Project Screening and Design) Jump to: navigation, search Stage 2 LEDS Home Introduction to Framework Assess current country plans, policies, practices, and capacities Develop_BAU Stage 4: Prioritizing and Planning for Actions Begin execution of implementation plans 1.0. Organizing the LEDS Process 1.1. Institutional Structure for LEDS 1.2. Workplan to Develop the LEDS 1.3. Roles and responsibilities to develop LEDS 2.1. Assess current country plans, policies, practices, and capacities 2.2. Compile lessons learned and good practices from ongoing and previous sustainable development efforts in the country 2.3. Assess public and private sector capacity to support initiatives 2.4. Assess and improve the national GHG inventory and other

454

Method for manufacturing a well production and sand screen assembly  

SciTech Connect

A method for forming and assembling a well production and sand screen assembly in a well having a screen therein forming an outer annulus and a wash pipe internally of the screen forming an inner annulus comprising further (A) mounting a high pressure fluid pump means and a valve means on each wash pipe, inner annulus, and outer annulus, and (B) connecting the valve means in fluid communication with the high pressure fluid pump means for controlling the ingress and egress of the high pressure fluids and removed formation material for forming a sand pack in the well and simultaneously for applying and maintaining a positive fluid pressure against the overburden during work in the well for preventing cave-ins and sloughing of the unconsolidated formation well walls until the sand pack is formed.

Widmyer, R.H.

1982-10-12T23:59:59.000Z

455

Gauss-Codazzi thermodynamics on the timelike screen  

Science Conference Proceedings (OSTI)

It is a known result by Jacobson that the flux of energy matter through a local Rindler horizon is related with the expansion of the null generators in a way that mirrors the first law of thermodynamics. We extend such a result to a timelike screen of observers with finite acceleration. Since timelike curves have more freedom than null geodesics, the construction is more involved than Jacobson's and few geometrical constraints need to be imposed: the observers' acceleration has to be constant in time and everywhere orthogonal to the screen. Moreover, at any given time, the extrinsic curvature of the screen has to be flat. The latter requirement can be weakened by asking that the extrinsic curvature, if present at the beginning, evolves in time like on a cone and just rescales proportionally to the expansion.

Piazza, Federico [Perimeter Institute for Theoretical Physics, Waterloo, Ontario, N2L 2Y5 (Canada)

2010-10-15T23:59:59.000Z

456

Walla Walla River Basin Screening, Annual Report 2002.  

DOE Green Energy (OSTI)

In order to meet the need for protective fish screening, the Walla Walla County Conservation District (WWCCD) and the Washington Department of Fish and Wildlife (WDFW) formed a partnership to implement the WDFW Cooperative Compliance Review and Cost-Share Program. The program provides technical and financial assistance to irrigators in order to bring existing surface water diversions into compliance with state and federal juvenile fish screen criteria. The Walla Walla basin has two priority salmonid species currently listed as threatened under the Endangered Species Act, the Bull Trout and Mid-Columbia Basin Steelhead. Other partners in this effort include the Washington Department of Ecology, National Marine Fisheries Service, US Fish and Wildlife Service, and the Walla Walla Community College Irrigation Department. A Screening Oversight Committee of representatives from these agencies sets policy and resolves issues.

Ahmann, Audrey; Jones, Rick

2003-02-01T23:59:59.000Z

457

Simplified economic screening models for enhanced oil recovery processes  

Science Conference Proceedings (OSTI)

The effective screening of reservoirs for implementation of enhanced oil recovery processes is critical to the financial success of a proposed project. Screening techniques that have been used in the past normally consisted of comparing individual reservoir and fluid properties with tables of the preferred values of these properties. The shortcoming of this procedure is that it does not account for interactions among the technical parameters, nor does it provide a measure of the economic attractiveness of the project. Intercomp has developed, under the sponsorship of the Bartlesville Energy Technology Center of DOE, a set of economic screening models for micellar-polymer, steam drive and CO/sub 2/ miscible EOR processes. These models include accurate oil production predictive algorithms and routines which provide measures of economic attractiveness based on time value of money economics. The formulation of these models is presented with examples of their use.

Paul, G.W.; Ford, M.

1982-08-01T23:59:59.000Z

458

Iowa Army Ammunition Plant Former Workers, Construction Worker Screening  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Iowa Army Ammunition Plant Former Workers, Construction Worker Iowa Army Ammunition Plant Former Workers, Construction Worker Screening Projects Iowa Army Ammunition Plant Former Workers, Construction Worker Screening Projects Project Name: Medical Monitoring of Former Atomic Weapons Workers at the Iowa Army Ammunition Plant (IAAP) in Burlington, Iowa Covered DOE Site: IAAP Worker Population Served: All Line 1/Division B Workers Principal Investigator: Laurence Fuortes, MD Toll-free Telephone: (866) 282-5818 Local Medical Clinics: University of Iowa Hospitals and Clinics 200 Hawkins Drive Iowa City, IA 52242 Henry County Health Center 407 South White Street Mt. Pleasant, IA 62641 Great River Medical Center 1221 S. Gear Avenue West Burlington, IA 52655 Website: http://cph.uiowa.edu/iowafwp/ This project is intended to screen for occupational health conditions among

459

Morphology-guided graph search for untangling objects: C. elegans analysis  

Science Conference Proceedings (OSTI)

We present a novel approach for extracting cluttered objects based on their morphological properties. Specifically, we address the problem of untangling Caenorhabditis elegans clusters in high-throughput screening experiments. We represent the skeleton ...

Tammy Riklin Raviv; V. Ljosa; A. L. Conery; F. M. Ausubelc; A. E. Carpenter; P. Golland; C. Whlby

2010-09-01T23:59:59.000Z

460

F  

NLE Websites -- All DOE Office Websites (Extended Search)

o r P e e r R e v i e w Journal Name: http:mc.manuscriptcentral.comindbiotech Lignocellulose Recalcitrance Screening by Integrated High Throughput Hydrothermal Pretreatment and...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Microsoft PowerPoint - Effective Exploration of New_Zhao [Compatibilit...  

NLE Websites -- All DOE Office Websites (Extended Search)

phases through high-throughput exploration together with computational thermodynamics. * Cost-effective steels for AUSC clean coal systems. Fe Ni Al, Nb, Ti, Si, Ta,...

462

Dynamic 3-D Digital Structure: Program Overview  

Science Conference Proceedings (OSTI)

High-Speed Fracture Phenomena of Glass Bottle by Underwater Shock Wave High-throughput Evaluation of Crystallization Temperature of Pd-Cu-Si System...

463

Derivation of the New Pressurized Thermal Shock Screening Criteria  

Science Conference Proceedings (OSTI)

As a result of a multi-year, multi-disciplinary effort on the part of the United States Nuclear Regulatory Commission (USNRC), its contractors, and the nuclear industry, a technical basis has been established to support a risk-informed revision to pressurized thermal shock (PTS) regulations originally promulgated in the mid-1980s. The revised regulations provide alternative (optional) reference-temperature (RT)-based screening criteria, which is codified in 10 CFR 50.61(a). How the revised screening criteria were determined from the results of the probabilistic fracture mechanics (PFM) analyses will be discussed in this paper.

Dickson, Terry L [ORNL; Yin, Shengjun [ORNL; Kirk, Mark [NRC; Chou, Hsuing-Wei [Institute of Nuclear Energy Research, Taiwan

2011-01-01T23:59:59.000Z

464

B133 Facility Screening Report (SCR)  

Science Conference Proceedings (OSTI)

B133 is located in the southwest quadrant inside the 1 square mile site of Lawrence Livermore National Laboratory. The property is about 250 meters from the nearest boundary along Vasco Road. Building 133 is a 1 story steel framed building constructed in 1994 with stainless steel sidings. The facility covers 5,631 gross square feet of space. The building is used to house equipment to heat and cool buildings 132N and 132S. A 1380 volts electrical substation is located outside on the northeast corner, along with 2 diesel generators and a 1000 gallons diesel fuel tank. An evaporative cooling tower is located to the south of B133 to dissipate heat from the chillers located in B133. The inside of the facility is divided into three main rooms housing the cooling system units, the boilers, and the electrical distribution panels. The facility has an automatic sprinkler system installed through out and a Freon alarm located in room 1000. Building 133 is used to supply electrical power, chilled water, and hot water to Bldgs 132 N & S. Primary activities include servicing and maintaining chillers, boilers, and electrical distribution equipment.

Cooper, G

2007-01-26T23:59:59.000Z

465

Mixed Alcohol Synthesis Catalyst Screening 2007 Progress Report  

DOE Green Energy (OSTI)

Pacific Northwest National Laboratory (PNNL) and National Renewable Energy Laboratory (NREL) are researching the feasibility of producing mixed alcohols from biomass-derived synthesis gas (syngas). PNNL is obtaining commercially available mixed alcohol or preparing promising mixed-alcohol catalysts and screening them in a laboratory-scale reactor system. The most promising catalysts are provided to NREL for testing using a slipstream from a pilot-scale biomass gasifier. After a review of the literature in 2006 and conversations with companies that produce catalysts, it was determined that no commercial mixed-alcohol synthesis catalysts were available. One manufacturer supplied a modified methanol catalyst that was tested in the PNNL laboratory-scale system and provided to NREL for further testing. PNNL also prepared and tested the behavior of 10 other catalysts representing the distinct catalyst classes for mixed alcohol syntheses. Based on those results,testing in 2007 focused on the performance of the rhodium-based catalysts. The effects of adding promoters to the rhodium catalysts in addition to the manganese already being used were examined. The iron and rhenium promoters both stood out as achieving higher carbon selectivities , followed by Cu. Iridium and Li, on the other hand, had low carbon selectivity ratios of 0.27 and 0.22, respectively. Although testing of candidate promoters is not complete, it appears that Ir and Li promoters warrant further optimization and possibly combination to further improve STYs and carbon selectivities to C2+ oxygenates. However, using these promoters, it will be necessary to incorporate a separate hydrogenation catalyst to improve the yield of C2+ alcohols with respect to the other oxygenates. Fe, Re, and Cu stand out as possible candidates in this respect, but additional research is needed to examine whether they can be combined with the other promoters on the Rh-based catalyst or need to be optimized on a separate catalyst support that is either physically mixed or used in series with the promoted Rh-based catalyst.

Gerber, Mark A.; White, J. F.; Gray, Michel J.; Stevens, Don J.

2007-11-01T23:59:59.000Z

466

Screening of nuclear pairing in nuclear and neutron matter  

E-Print Network (OSTI)

The screening potential in the $^1S_0$ and $^3S_1$ pairing channels in neutron and nuclear matter in different approximations is discussed. It is found that the vertex corrections to the potential are much stronger in nuclear matter than in neutron matter.

Caiwan Shen; Umberto Lombardo; Peter Schuck

2005-03-03T23:59:59.000Z

467

Colon Cancer Screening The Good, the Bad, and the Ugly  

E-Print Network (OSTI)

older than 50 years. There are sev- eral recommended CRC screening tests, including fecal occult blood- vasiveness, discomfort, and accuracy.2 Fecal occult blood testing is the least expensive intrusive test, whereas colo- noscopy is the most accurate but also the most invasive test. Fecal occult blood testing

Ottino, Julio M.

468

Electron Screening in 7Be + p --> 8B + photon reaction  

E-Print Network (OSTI)

We evaluate the effect of screening by bound electron in (7Be,e) + p --> (8B,e) + photon transition in the framework of the adiabatic representation of the three particle problem. Comparison with two approaches (united nucleus and static) is presented. We discuss possible applications of this effect both for Solar Neutrinos and low energy fusion experiments.

V. B. Belyaev; D. E. Monakhov; D. V. Naumov; F. M. Penkov

1998-03-02T23:59:59.000Z

469

Is Screening Cargo Containers for Smuggled Nuclear Threats Worthwhile?  

Science Conference Proceedings (OSTI)

In recent years, Customs and Border Protection has installed radiation sensors to screen cargo containers entering the United States. They are concerned that terrorists could use containers to smuggle radiological material into the country and carry ... Keywords: applications, multiple-objective decision analysis, probability, terrorism

Jason R. W. Merrick; Laura A. McLay

2010-06-01T23:59:59.000Z

470

Fatigue failure of regenerator screens in a high frequency Stirling engine  

DOE Green Energy (OSTI)

Failure of Stirling Space Power Demonstrator Engine (SPDE) regenerator screens was investigated. After several hours of operation the SPDE was shut down for inspection and upon removal of the regenerator screens, debris of an unknown origin was discovered along with considerable cracking of the screens in localized areas. Metallurgical analysis of the debris determined it to be cracked-off-deformed pieces of the 41 pm thickness Type 304 stainless steel wire screen. Scanning electron microscopy of the cracked screens revealed failures occurring at wire crossovers and fatigue striations on the fracture surface of the wires. Thus, the screen failure can be characterized as a fatigue failure of the wires. The crossovers were determined to contain a 30 percent reduction in wire thickness and a highly worked microstructure occurring from the manufacturing process of the wire screens. Later it was found that reduction in wire thickness occurred because the screen fabricator had subjected the screen to a light cold-roll process after weaving. Installation of this screen left a clearance in the regenerator allowing the screens to move. The combined effects of the reduction in wire thickness, stress concentration (caused by screen movement), and highly worked microstructure at the wire crossovers led to the fatigue failure of the screens.

Hull, D.R.; Alger, D.L.; Moore, T.J.; Sheuermann, C.M.

1987-03-01T23:59:59.000Z

471

Survey and screening of intermediate-size photovoltaic total energy and electric applications  

DOE Green Energy (OSTI)

One of the principal objectives of this photovoltaic mission analysis effort has been to identify and evaluate applications for photovoltaic solar energy conversion that could lead to significant contributions to the national energy supply and that would provide attractive opportunities for application experiments aimed at stimulating the adoption of photovoltaic technology. The scope of the study has included applications both for electric-only photovoltaic (PV) systems and for photovoltaic total energy systems (PTES), i.e., systems that provide both photovoltaic electricity and solar thermal energy to meet all or part of the energy demand at a single load point or a group of related load points. In either case, both flat-plate and concentrating systems have been considered and it has been assumed that the thermal energy is collected in and transported by the fluid used in an active cooling system for the photovoltaic cells. Because the efficiency of photovoltaic devices decreases rapidly with increasing temperature and because the operational lifetime of such devices is reduced by prolonged operation at elevated temperatures, a practical upper limit of about 200/sup 0/C (400/sup 0/F) was assumed for the temperature at which arrays can be allowed to be operated. This limitation, in turn, places an upper bound on the temperature at which solar thermal energy is available in PTES applications. An initial screening aimed at identifying the most promising applications has therefore been required, with the expectation that detailed evaluation will be made of only the higher-ranking candidates. A description of the screening procedure that was adopted and a discussion of the results are presented.

Rattin, E.J.

1978-08-01T23:59:59.000Z

472

Using the Domain Name System to Thwart Automated Client-Based Attacks  

SciTech Connect

On the Internet, attackers can compromise systems owned by other people and then use these systems to launch attacks automatically. When attacks such as phishing or SQL injections are successful, they can have negative consequences including server downtime and the loss of sensitive information. Current methods to prevent such attacks are limited in that they are application-specific, or fail to block attackers. Phishing attempts can be stopped with email filters, but if the attacker manages to successfully bypass these filters, then the user must determine if the email is legitimate or not. Unfortunately, they often are unable to do so. Since attackers have a low success rate, they attempt to compensate for it in volume. In order to have this high throughput, attackers take shortcuts and break protocols. We use this knowledge to address these issues by implementing a system that can detect malicious activity and use it to block attacks. If the client fails to follow proper procedure, they can be classified as an attacker. Once an attacker has been discovered, they will be isolated and monitored. This can be accomplished using existing software in Ubuntu Linux applications, along with our custom wrapper application. After running the system and seeing its performance on three popular Web browsers Chromium, Firefox and Internet Explorer as well as two popular email clients, Thunderbird and Evolution, we found that not only is this system conceivable, it is effective and has low overhead.

Taylor, Curtis R [ORNL; Shue, Craig A [ORNL

2011-09-01T23:59:59.000Z

473

Advanced polymer PV system: PVMaT 4A1 annual report, September 1995--September 1996  

DOE Green Energy (OSTI)

Purpose of this subcontract was to produce lower module and systems costs through the innovative use of polymeric materials. The Innovative Mounting System (IMS) was developed and testing begun during the first year of this contract. IMS reduces the cost of installed PV systems by reducing labor and materials costs both in the factory and in field installation. It incorporates several advances in polymers, processing methods and product design. An advanced backskin material permits elimination of the conventional Al perimeter frame by protecting and sealing the edge and by direct bonding of multifunctional mounting bars. Electrical interconnection is easier and more reliable with a new junction box. Feasibility of a non-vacuum, high-throughput lamination method was also demonstrated, involving a novel transparent encapsulant with UV stabilization package that can be laminated in air and which should lead to longer field life than conventional designs. The first-year program culminated in the fielding of prototype products with the new encapsulant, backskin, junction box, frameless edge seal, and IMS. Feedback and marketing information from potential customers were solicited. Result promises a $0.50/watt manufacturing and system cost reductions as well as increased system lifetime. The second year will complete refinement and test of the encapsulant and backskin, complete the new lamination method, and refine product designs.

Hanoka, J.; Chleboski, R.; Farber, M.; Fava, J.; Kane, P.; Martz, J. [Evergreen Solar, Inc., Waltham, MA (United States)

1997-06-01T23:59:59.000Z

474

The development of a drug discovery virtual screening application on Taiwan unigrid  

Science Conference Proceedings (OSTI)

This paper describes the development of an in silico virtual screening application on Taiwan Unigrid. In silico virtual screening is one of the most promising approach to accelerate the drug development process. This pilot application implementation ...

Li-Yung Ho; Pangfeng Liu; Chien-Min Wang; Jan-Jan Wu

2008-05-01T23:59:59.000Z

475

Cost-Effectiveness of a Mailed Educational Reminder to Increase Colorectal Cancer Screening  

E-Print Network (OSTI)

controlled trial of faecal-occult-blood screening forcancer with faecal-occult-blood test. Lancet 1996, 348:1467-by screening for fecal occult blood. Minnesota Colon Cancer

Lee, Jeffrey K; Groessl, Erik J; Ganiats, Theodore G; Ho, Samuel B

2011-01-01T23:59:59.000Z

476

A Pilot Study of Lay Health Worker Outreach and Colorectal Cancer Screening Among Chinese Americans  

E-Print Network (OSTI)

by screening for fecal occult blood. Minnesota Colon Cancercontrolled trial of faecal-occult-blood screening forat baseline to 55.7% for fecal occult blood tests, 7.1% for

2010-01-01T23:59:59.000Z

477

In vivo boron-10 analysis for the pre-screening of compounds for BNCS  

E-Print Network (OSTI)

An in vivo boron-10 screening technique was developed to analyze the boron biodistribution in a rabbit knee for the pre-screening of compounds for Boron Neutron Capture Synovectomy (BNCS). Three approaches were investigated: ...

Zhu, Xuping, 1970-

2004-01-01T23:59:59.000Z

478

Velocity Measurements at Three Fish Screening Facilities in the Yakima Basin, Washington : Summer 1989 Annual Report.  

DOE Green Energy (OSTI)

The Pacific Northwest Laboratory (PNL) measured the velocity conditions at three fish screening facilities in the Yakima River Basin: Wapato, Chandler, and Easton Screens. The measurement objectives were different at the three screens. At Wapato, approach and sweep velocities were measured to evaluate the effect of rearing pens in the screen forebay. A complete survey was performed at the Chandler Screens. At Easton, velocity was measured behind the screens to provide information for the installation of porosity boards to balance flow through the screens. Salmon-rearing pens used at the Wapato Canal had a minimal effect on the magnitude of approach and sweep velocities at the face of the drum screens, although the pens caused increased turbulence and variability in water velocities. The net pens did not appear to affect flows through the three fish bypasses. 8 refs., 17 figs., 5 tabs.

Abernethy, C. Scott; Neitzel, Duane A.; Lusty, E. William

1990-09-01T23:59:59.000Z

479

Environmental Impact Assesment in the Baltic Countries and Poland -- Screening and Quality Control  

E-Print Network (OSTI)

In The Baltic Countries And Poland - Screening And QualityIn The Baltic Countries And Poland - Screening And QualityLatvia, Lithuania and Poland. All four of these countries

Marriott, A.; Doughty, M.

1997-01-01T23:59:59.000Z

480

A Screening Method for Guiding R&D Decisions: Pilot Application...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

A Screening Method for Guiding R&D Decisions: Pilot Application to Nuclear Fuel Cycle Options A Screening Method for Guiding R&D Decisions: Pilot Application to Nuclear Fuel Cycle...

Note: This page contains sample records for the topic "high-throughput screening system" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Circulating Fluid-Bed Technology for Advanced Power Systems  

Science Conference Proceedings (OSTI)

Circulating fluid bed technology offers the advantages of a plug flow, yet well-mixed, and high throughput reactor for power plant applications. The ability to effectively scale these systems in size, geometry, and operating conditions is limited because of the extensive deviation from ideal dilute gas-solids flow behavior (Monazam et al., 2001; Li, 1994). Two fluid computations show promise of accurately simulating the hydrodynamics in the riser circulating fluid bed; however, validation tests for large vessels with materials of interest to the power industry are lacking (Guenther et al., 2002). There is little available data in reactors large enough so that geometry (i.e. entrance, exit, and wall) effects do not dominate the hydrodynamics, yet with sufficiently large particle sizes to allow sufficiently large grid sizes to allow accurate and timely hydrodynamic simulations. To meet this need experimental tests were undertaken with relatively large particles of narrow size distribution in a large enough unit to reduce the contributions of wall effects and light enough to avoid geometry effects. While computational fluid dynamic calculations are capable of generating detailed velocity and density profiles, it is believed that the validation and model development begins with the ability to simulate the global flow regime transitions. The purpose of this research is to generate well-defined test data for model validation and to identify and measure critical parameters needed for these simulations.

Shadle, Lawrence J.; Ludlow, J. Christopher; Mei, Joseph S. (U.S. DOE National Energy Technology Laboratory); Guenther, Christopher (Fluent, Inc.)

2001-11-06T23:59:59.000Z

482

Combinatorial screening for the identification of Mg-based destabilized  

NLE Websites -- All DOE Office Websites (Extended Search)

Combinatorial screening for the identification of Mg-based destabilized Combinatorial screening for the identification of Mg-based destabilized hydrogen storage materials Speaker(s): Robin Gremaud Date: October 16, 2006 - 12:00pm Location: 90-3122 Limited energy resources and increasing pollution associated with the use of fossil resources have stimulated the search for cleaner, cheaper and more efficient energy technologies. One promising technology involves hydrogen that can be used in fuel cells and is stored in metal hydrides. However, for replacing existing technologies, still a large number of problems have to be solved, demanding for extensive fundamental research in the field of material science. Our experimental strategy, aimed at finding of novel (complex) hydrides is to carry out systematic experiments for various light-weight metal-hydrides. In the standard approach followed so

483

Portsmouth Gaseous Diffusion Plant, Former Production Workers Screening  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Portsmouth Gaseous Diffusion Plant, Former Production Workers Portsmouth Gaseous Diffusion Plant, Former Production Workers Screening Projects Portsmouth Gaseous Diffusion Plant, Former Production Workers Screening Projects Project Name: Worker Health Protection Program Covered DOE Site: Portsmouth Worker Population Served: Production Workers Principal Investigator: Jim Frederick Co-Principal Investigator: Steven Markowitz, MD Toll-free Telephone: (888) 241-1199 Local Outreach Office: Jeanne Cisco 2288 Wakefield Mound Road Piketon, OH 45661 Website: http://www.worker-health.org/ This project is conducted by the Unitedsteel Workers in conjunction with Queens College of the City University of New York. The program is being offered as a service to both former and current workers. Free of charge, eligible workers can receive a medical exam, including chest X-ray and

484

Argonne National Laboratory-West, Former Production Workers Screening  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

West, Former Production Workers West, Former Production Workers Screening Projects (now known as the Idaho National Laboratory) Argonne National Laboratory-West, Former Production Workers Screening Projects (now known as the Idaho National Laboratory) Project Name: Worker Health Protection Program Covered DOE Site: Argonne National Laboratory-West Worker Population Served: Production Workers Principal Investigator: Jim Frederick Co-Principal Investigator: Steven Markowitz, MD Toll-free Telephone: (888) 241-1199 Local Outreach Office: David Fry 1055 Austin Avenue Idaho Falls, ID 83404 Website: http://www.worker-health.org/ This project is conducted by the United Steelworkers, in partnership with Queens College of the City University of New York. Free of charge, eligible workers can receive a medical exam, including chest X-ray and breathing

485

Joint Outreach Task Group Former Workers Screening Program | Department of  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Joint Joint Outreach Task Group Former Workers Screening Program Joint Outreach Task Group Former Workers Screening Program The Joint Outreach Task Group (JOTG) includes representatives from HSS, Department of Labor (DOL), the National Institute for Occupational Safety and Health (NIOSH), the Offices of the Ombudsman for DOL and NIOSH, and the DOE-funded FWP projects. The JOTG was established in 2009 under the premise that agencies/programs with common goals can work together by combining resources and coordinating outreach efforts. Each involved agency has a different mission, but the missions are complementary. By working together, the agencies are better able to serve the DOE workforce. The JOTG focuses on educating the former workers on the programs and resources available to them.