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Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

Haiti Repowered | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of InspectorConcentrating Solar Power BasicsGermany: EnergyPower Finance Jump to: navigation,IncHaiti Repowered

2

Converting sugarcane waste into charcoal for Haiti  

E-Print Network [OSTI]

In Haiti, most families have traditionally relied on wood and wood-derived charcoal as their primary fuel source for indoor cooking. This resource has proven to be unsustainable, however, as over 90% of the Haitian countryside ...

Toussaint, Etienne Clement

2007-01-01T23:59:59.000Z

3

Economic feasibility of bagasse charcoal in Haiti  

E-Print Network [OSTI]

The economics of implementing bagasse-based charcoal manufacturing in Haiti was investigated. From these main inputs, three different manufacturing economic scenarios were modeled using a simple, dynamic excel spreadsheet. ...

Kamimoto, Lynn K. (Lynn Kam Oi)

2005-01-01T23:59:59.000Z

4

Haiti-Caribbean Community (CARICOM) Sustainable Energy Roadmap...  

Open Energy Info (EERE)

Caribbean Community (CARICOM) Sustainable Energy Roadmap and Strategy Jump to: navigation, search Name Haiti-Caribbean Community (CARICOM) Sustainable Energy Roadmap and Strategy...

5

Haiti: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti: Energy Resources

6

RAs  

National Nuclear Security Administration (NNSA)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartmentNationalRestart of the Review of theOFFICE OF CIVIL RIGHTS/%2A contractor6/%2A en

7

E-Print Network 3.0 - aids haiti relief Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Experience: Where research training meets the world Summary: . Current locations include Bangladesh, Botswana, Brazil, China, Haiti, India, Kenya, Malawi, Mali, Peru... of...

8

Children Are the Wealth of the Poor: Prevention of Mother-to-Child Transmission of HIV in Haiti  

E-Print Network [OSTI]

At roughly two percent, Haiti has one of the highest HIV prevalence rates in the Caribbean. This thesis examines HIV transmission in Haiti, specifically the transmission of HIV from mother to child during pregnancy, labor, ...

Denney, Rachel

2012-08-31T23:59:59.000Z

9

RAS FRIDAYS A Monthly Networking Meeting for FAS Research Administrators  

E-Print Network [OSTI]

RAS FRIDAYS A Monthly Networking Meeting for FAS Research Administrators RAS FRIDAY MEETING AGENDA to Research Administration Services (RAS) Friday Patrick Fitzgerald Associate Dean for Research Administration FAS Research Administration Services (RAS) 10:10 Office for Technology Development Updates Julie

10

Haiti-Facility for Environmentally Friendly Transport Technology and  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of InspectorConcentrating Solar Power BasicsGermany: EnergyPower Finance Jump to: navigation,IncHaiti

11

College of Health Sciences RAS Radiation Sciences  

E-Print Network [OSTI]

; excitation and ionization processes; selected nuclear reactions; basic radiation detection and dosimetry, and nuclear medical physics. Prereq or concur: RM/PHY 472G or consent of instructor. (Same as PHY/RM 546.) RAS 601 ADVANCED RADIATION DOSIMETRY. (2

MacAdam, Keith

12

E-Print Network 3.0 - activating ras mutations Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Collection: Biology and Medicine 3 R342 Dispatch Ras effectors: Buying shares in Ras plc Summary: of hamster fibroblast proliferation by mutated ras oncogenes is not mediated...

13

COMMENT: Don't fall for Washington's spin on Haiti By Jeffrey Sachs  

E-Print Network [OSTI]

(and perhaps current) CIA operatives, worked Washington to lobby against Mr Aristide. In 2000, Haiti is stunning. What has been the CIA's role among the anti-Aristide rebels? How much US money went from US

14

Design and implementation of a solar power system in rural Haiti  

E-Print Network [OSTI]

This paper describes the design and implementation of a solar power system for a school and health center in Petit-Anse, Haiti. The end-use applications are lighting via a set of fluorescent and incandescent bulbs, and a ...

Hussam, Shaheer M. (Shaheer Muqtasid), 1981-

2004-01-01T23:59:59.000Z

15

Design of a press for oil extraction from moringa seeds for Haiti  

E-Print Network [OSTI]

The project here presented focuses on the development of a harvesting tool for Haiti, a developing country, for the extraction of oil from the seeds of the moringa trees. Moringas have an extraordinarily nutritional potential ...

Sabelli, Alessandra Maria, 1976-

2004-01-01T23:59:59.000Z

16

Design of a bagasse charcoal briquette-making device for use in Haiti  

E-Print Network [OSTI]

Charcoal made from bagasse, the fibrous remains of sugarcane production, has the potential to serve as an alternate cooking fuel in Haiti, where the reliance on wood has led to severe deforestation. Current production ...

Vechakul, Jessica

2005-01-01T23:59:59.000Z

17

Analysis for the Design of a Sustainable Housing Complex in Haiti  

E-Print Network [OSTI]

is considered to be a modern day form of slavery by the Unite Nations[10]. Haiti also has limited energy resources. The country has no petroleum resources, little hydroelectricity potential, and rapidly diminishing supplies of wood fuels. Wood accounts...

Dinka, M.; Cho, S.

18

Opportunity in Haiti : women as agents of resilience in post-disaster reconstruction  

E-Print Network [OSTI]

The earthquake that struck Haiti on January 12, 2010, caused severe spatial and social disruption of many communities. Over the past sixteen months, as international and national institutions struggled to respond in an ...

Brickman Raredon, Anya

2011-01-01T23:59:59.000Z

19

E-Print Network 3.0 - activated ras signalling Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Collection: Biology and Medicine 5 R342 Dispatch Ras effectors: Buying shares in Ras plc Summary: . In this state, Ras is consti- tutively active and can transmit signals for...

20

The C-Terminus of H-Ras as a Target for the Covalent Binding of Reactive Compounds Modulating Ras-  

E-Print Network [OSTI]

´ficas, Madrid, Spain, 2 Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain, 3 Department of Organic Chemistry, Faculty of Sciences, University of Ma´laga, Ma´laga, Spain, 4 Microbiologi´a, Instituto de Salud Carlos III, Madrid, Spain Abstract Ras proteins are crucial players

Pompeu Fabra, Universitat

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Haiti: Feasibility of Waste-to-Energy Options at the Trutier Waste Site  

SciTech Connect (OSTI)

This report provides further analysis of the feasibility of a waste-to-energy (WTE) facility in the area near Port-au-Prince, Haiti. NREL's previous analysis and reports identified anaerobic digestion (AD) as the optimal WTE technology at the facility. Building on the prior analyses, this report evaluates the conceptual financial and technical viability of implementing a combined waste management and electrical power production strategy by constructing a WTE facility at the existing Trutier waste site north of Port-au-Prince.

Conrad, M. D.; Hunsberger, R.; Ness, J. E.; Harris, T.; Raibley, T.; Ursillo, P.

2014-08-01T23:59:59.000Z

22

Effects of oncogenic Ras and p38 mitogen-activated protein kinase on the adhesion of normal human cells  

E-Print Network [OSTI]

Activating mutations in RAS oncogenes commonly arise in human cancers. However, in experimental settings, oncogenic RAS has most often been studied at supraphysiological levels of expression. Importantly, work by others ...

Waldman, Lynne K

2010-01-01T23:59:59.000Z

23

Haiti Soil Fertility Analysis and Crop Interpretations for Principal Crops in the Five WINNER Watershed Zones of Intervention  

E-Print Network [OSTI]

Central Intelligence Agency (US-CIA), data 9.7 million Haitians live within the borders of the 27,750 km2. In contrast, only 3.4% of the Haitian population is 65 and 51% is 20 (US-CIA, 2011). Forty seven percent of the population of Haiti lives in urban areas according to recent data (US-CIA, 2011); however, the city of Port

Ma, Lena

24

Performance of Charcoal Cookstoves for Haiti Part 1: Results from the Water Boiling Test  

SciTech Connect (OSTI)

In April 2010, a team of scientists and engineers from Lawrence Berkeley National Lab (LBNL) and UC Berkeley, with support from the Darfur Stoves Project (DSP), undertook a fact-finding mission to Haiti in order to assess needs and opportunities for cookstove intervention. Based on data collected from informal interviews with Haitians and NGOs, the team, Scott Sadlon, Robert Cheng, and Kayje Booker, identified and recommended stove testing and comparison as a high priority need that could be filled by LBNL. In response to that recommendation, five charcoal stoves were tested at the LBNL stove testing facility using a modified form of version 3 of the Shell Foundation Household Energy Project Water Boiling Test (WBT). The original protocol is available online. Stoves were tested for time to boil, thermal efficiency, specific fuel consumption, and emissions of CO, CO{sub 2}, and the ratio of CO/CO{sub 2}. In addition, Haitian user feedback and field observations over a subset of the stoves were combined with the experiences of the laboratory testing technicians to evaluate the usability of the stoves and their appropriateness for Haitian cooking. The laboratory results from emissions and efficiency testing and conclusions regarding usability of the stoves are presented in this report.

Booker, Kayje; Han, Tae Won; Granderson, Jessica; Jones, Jennifer; Lsk, Kathleen; Yang, Nina; Gadgil, Ashok

2011-06-01T23:59:59.000Z

25

Eighty-eight historical and present-day maps of Saint-Domingue/Haiti, its sites, towns, and islands  

E-Print Network [OSTI]

. Mart ial 31 Col lege St. Louis 32 de Gonzague 33 Church of St. Anne Hotel Splendid 34 Church of Sacrd Coeur 35 Marche de Fer ( I r on Marke t ) Batterie St.Clair Hotel de France Banque Nat ionale Dan A l i ens Restaurant Fort D imanche Fort...Occasional Paper N 20 Bryant C. Freeman Eighty-Eight Historical and Present-Day Maps of Saint-Domingue/Haiti, its Sites, Towns, and Islands Institute of Haitian Studies University of Kansas Occasional Paper N 20 Bryant C. Freeman Eighty...

Freeman, Bryant C.

1999-01-01T23:59:59.000Z

26

Ocheretina O, Morose W, Gauthier M, Joseph P, D'Meza R, Escuyer VE, et al. Multidrug-resistant tuberculosis in Port-au-Prince, Haiti. Rev Panam Salud Publica. 2012;31(3):2214.  

E-Print Network [OSTI]

and hybridization assays are good screening tools for early detection of MDR-TB. Tuberculosis, multidrug resistant, the Bahamas, the United States of America, Canada, France, and other parts of the francophone world (2). Haiti

Boyer, Edmond

27

RAS Mutations Impact TNF-Induced Apoptosis in Colon Carcinoma Cells via ERK-Modulatory Negative and Positive Feedback Circuits along with non-ERK Pathway Effects  

E-Print Network [OSTI]

More than 40% of colon cancers have a mutation in K-RAS or N-RAS, GTPases that operate as central hubs for multiple key signaling pathways within the cell. Utilizing an isogenic panel of colon carcinoma cells with K-RAS ...

Lauffenburger, Douglas A.

28

The effect of sociocultural factors on the quality of relations of the United States with Hispaniola: analysis of the American military occupation of Haiti and the Dominican Republic (1915-1934)  

E-Print Network [OSTI]

THE EFFECT OF SOCIOCULTURAL FACTORS ON THE QUALITY OF RELATIONS OF THE UNITED STATES WITH HISPANIOLA: ANALYSIS OF THE AMERICAN MILITARY OCCUPATION OF HAITI AND THE DOMINICAN REPUBLIC (1915-1934) A Thesis By FAUSTO B. ALVAREZ Submitted... WITH HISPANIOLA: ANALYSIS OF THE AMERICAN MILITARY OCCUPATION OF HAITI AND THE DOMINICAN REPUBLIC (1915-1934) A Thesis by FAUSTO B. ALVAREZ Approved as to style and content by: C arrperson o Co ee) ames H. Copp (Member) Wm. Alex McIntosh (Member) James...

Alvarez, Fausto B.

1988-01-01T23:59:59.000Z

29

RAS Mutations Affect Tumor Necrosis FactorInduced Apoptosis in Colon Carcinoma Cells via ERK-Modulatory Negative and Positive Feedback Circuits Along with Non-ERK Pathway Effects  

E-Print Network [OSTI]

More than 40% of colon cancers have a mutation in K-RAS or N-RAS, GTPases that operate as central hubs for multiple key signaling pathways within the cell. Utilizing an isogenic panel of colon carcinoma cells with K-RAS ...

Kreeger, Pamela K.

30

The C. elegans class A synthetic multivulva genes inhibit ectopic RAS-mediated vulval development by tightly restricting expression of lin-3 EGF  

E-Print Network [OSTI]

The class A and B synthetic multivulva (synMuv) genes of C. elegans redundantly antagonize an EGF/Ras pathway to prevent ectopic vulval induction. The class B synMuv genes encode many proteins known to remodel chromatin ...

Saffer, Adam M

2011-01-01T23:59:59.000Z

31

Time-resolved FTIR spectroscopy for monitoring protein dynamics exemplified by functional studies of Ras protein bound to a lipid bilayer  

E-Print Network [OSTI]

bilayers can be investigated in near physiological con- ditions with the attenuated total reflection (ATR online 22 August 2011 Keywords: Infrared Time-resolved Difference spectroscopy Rapid scan Step scan GTPases GTP Caged-substances Ras Isotopic labeling Band assignment Global fit Attenuated total reflection

Gerwert, Klaus

32

Nutritional Analysis of Thomazeau, Haiti  

E-Print Network [OSTI]

for the designation as UNDERGRADUATE RESEARCH SCHOLAR Approved by: Research Advisor: Dr. Christine A. Tisone, PhD, MPH May 2013 Major: International Studies ! ! 1! ! ! TABLE OF CONTENTS Page CONTENTS... Vanderpool Department of International Studies Texas A&M University Research Advisor: Dr. Christine A Tisone, PhD, MPH Department of Health and Kinesiology The long-term health of populations who have suffered through natural or man-made disaster...

Vanderpool, John Mark

2013-02-04T23:59:59.000Z

33

Haiti earthquake survivor to speak  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickr FlickrGuided Self-Assembly of GoldHAWCHIGSSite H-Area

34

UNIVERSITY OF CALIFORNIA HAITI INITIATIVE Executive Committee  

E-Print Network [OSTI]

(UEH-UC Collaboration) is a broad- based collaboration among university community members (eg. Students remotely. Focus groups will be organized as the UEH Rectorat prioritizes but will likely be broad areas-cultural, multi-disciplinary environment. · Conversational in French and/or Haitian Kreyol #12;

35

Haiti-NREL Cooperation | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways | OpenDHabusHaesung Solar|

36

Land Tenure and Reform in Haiti Amber Bethell  

E-Print Network [OSTI]

the island of Hispaniola in 1492. The wealth of the colony came from gold exports. The original inhabitants was almost extinct. The French were given the western 1/3 of Hispaniola in 1697 because the gold was mostly

Onsrud, Harlan J.

37

The Politics and Culture in the Mouvman Rasin in Haiti  

E-Print Network [OSTI]

of people. . . were politically and socially marginalized due to the US Occupation and the resulting mulatto control of the country after 1934" (page 1, and reiterated page 10) appears to overlook that fact that the Mulatto control of the country became... politically and socially marginalized due to the US Occupation and the resulting mulatto control of the country after 1934. Despite a low level of violence perpetuated by him before and after the election, Duvalier enjoyed some amount of popular support...

Jayaram, Kiran C.

2004-01-01T23:59:59.000Z

38

Volunteers hope ORNL technology will speed Haiti's long quake recovery  

E-Print Network [OSTI]

and voluntarily serve in medical clinics in Port au Prince. Hale--who works in the Reactor Nuclear Reporter 1 anniversaries . . . . . . . . . . . . 4 Haire receives Seaborg Award . . . . 4 Book describes fusion's fun side

Pennycook, Steve

39

Haiti-Caribbean Community (CARICOM) Sustainable Energy Roadmap and Strategy  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways | OpenDHabusHaesung Solar|

40

Haiti-Regional Implementation Plan for CARICOM's Climate Change  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Haiti - Annual Average Wind Speed at 80 meters  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky9, 2010 The meeting wasEngineeringDepartment of Energy 74°

42

Haiti-IAEA Energy Planning | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of InspectorConcentrating Solar Power BasicsGermany: EnergyPower Finance Jump to: navigation,IncHaitidatabase-

43

Characterization of a putative novel Ras effector in Dictyostelium discoideum  

E-Print Network [OSTI]

pellet and supernatant samples were separated on SDS- PAGE and analyzed with Coomassie staining. Mass Production

Taylor, Natalie Marie

2008-01-01T23:59:59.000Z

44

assessment scale ras: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Kundur two area test system which exhibits an interarea oscillatory mode. Key words: Remedial action Venkatasubramanian, Mani V. 47 Self, Society, and Environment in the 21st...

45

Resilient Asymmetric Security (RAS) Salim Hariri, UA Director  

E-Print Network [OSTI]

services will revolutionize the way we do business, maintain our health, conduct education, and how secure self-*, i.e., autonomic operations. To address these challenges, we are developing a Resilient

46

Astrium Satellites UK Lunar Polar Lander meeting, RAS  

E-Print Network [OSTI]

Propulsion Systems Mechanisms ExoMars Rover Portsmouth: Radar Systems -> Landing Passive Microwave 2018 Under development In orbit Exosat 1983 Hipparcos 1989 Solar Orbiter Planetary Science SolarAstrium.Itshallnotbecommunicatedtothirdpartieswithoutpriorwrittenagreement.Itscontentshallnotbedisclosed. Concept Design Based on these trade-results 2 concepts have been selected for further design Option 1

Anand, Mahesh

47

automation society ras: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Engineering (T-ASE) February 2003: First Issue to appear in mid 2004. Executive Summary Automation plays an increasingly important role in the global economy and in our daily...

48

Aberrant Ras/MAPK signaling in skeletal development  

E-Print Network [OSTI]

The Mitogen-activated protein kinase(MAPK) signaling pathway has been studied intensively in the context of neoplastic transformation. Other studies have focused on the roles of this pathway during development and have ...

Nedelcu, Simona

2013-01-01T23:59:59.000Z

49

activated ras alters: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

in chronic human spinal cord injury Katherine M. Deutscha, b, T. George Hornbya, c, Brian D joint torques at the ankle, knee and hip. The results showed that SCI individuals...

50

In her RAS Presidential Address for 2005, Kathryn A Whaler  

E-Print Network [OSTI]

, the magnetic field source is sferics associated with thunderstorms; at longer periods, solar activity equipment loaned from the Nat- ural Environment Research Council's Geophys- ical Equipment Facility

51

DIGGING THE ROOTS or Resistance and identity politics of the mouvman rasin in Haiti  

E-Print Network [OSTI]

re going to uproot you Nou pa p gaz We dont fear tear gas Nou gen sitwon We have limes (to counteract it)72 This chant indicated that people no longer resigned themselves to be zonbi-s under the regime. They were willing to do what...

Jayaram, Kiran C.

2002-01-01T23:59:59.000Z

52

Two New Species of Amphisbaena (Reptilia: Squamata: Amphisbaenidae) from the Tiburon Peninsula of Haiti  

E-Print Network [OSTI]

@uprrp.edu ABSTRACT.--Hispaniola and its included islands of Ile de la Gonave and Grande Cayemite are currently not previ- ously reported for Antillean Amphisbaena. KEYWORDS.--Hispaniola, West Indies, Amphisbaenia), Hispaniola (five), and Puerto Rico (five). The genus is absent from Ja- maica, the Bahamas, and other island

Hedges, Blair

53

Woody and Herbaceous Plants Native to Haiti For use in Miami-Dade Landscapes1  

E-Print Network [OSTI]

occupies the western one third of the island of Hispaniola with the Dominican Republic the remainder. Of all the islands within the Caribbean basin Hispaniola possesses the most varied flora after

Jawitz, James W.

54

An extinct monkey from Haiti and the origins of the Greater Antillean primates  

E-Print Network [OSTI]

primate dentition yet recorded, demonstrating the likely coexistence of two primate species on Hispaniola other genera, each one confined to a different island, have since been reported: in Hispaniola to material from Hispaniola are 3,850 ± 135 (3) and 9,550 ± 150 (11). Insulacebus toussaintiana represents

Rosenberger, Alfred H.

55

Solar-driven humidification dehumidification desalination for potable use in Haiti  

E-Print Network [OSTI]

Worldwide water scarcity, especially in the developing world, provides the impetus for utilizing inexpensive desalination technologies on a wider scale to contribute to freshwater supply. Small-scale desalination technologies, ...

Liburd, Shannon Omari

2010-01-01T23:59:59.000Z

56

Properties of soils in a toposequence on Cap Rouge Plateau, Haiti  

E-Print Network [OSTI]

saturation, organic carbon, CEC and coarse fragment contents. They were classified as loamy-skeletal, carbonatic, isohyperthermic, shallow, Eutropeptic Rendoll and clay-skeletal, carbonatic, isohyperthermic, Lithic Rendoll, respectively. Interpretations... Carbonate Equivalent Cation Exchange Capacity (CEC) Echangeable Bases. Extractable Iron and Aluminum. 38 38 40 40 43 46 47 Soil Mineralogical Properties. S i 1 t Mine ra 1 ogy . Clay Mineralogy. Soil Micromorphology Classification of the Soils...

Louis, Pierre Antoine

1985-01-01T23:59:59.000Z

57

Haiti-Pilot Program for Climate Resilience (PPCR) | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways | OpenDHabusHaesung

58

Haiti-Designing and Communicating Low Carbon Energy Roadmaps for Small  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revision hasInformation Earth's Heat Jump to:Photon Place:Net JumpStrategy | OpenHackberry Windgateway |Island

59

Haiti-Low-Carbon Energy Roadmaps for the Greater Antilles | Open Energy  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revision hasInformation Earth's Heat Jump to:Photon Place:Net JumpStrategy | OpenHackberry Windgateway

60

E-Print Network 3.0 - arons inara logina Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

State University Collection: Environmental Sciences and Ecology 2 Land Tenure and Reform in Haiti Amber Bethell Summary: are among the toughest challenges facing Haiti's...

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

CX-008556: Categorical Exclusion Determination  

Broader source: Energy.gov [DOE]

Haiti Renewable Resource Study CX(s) Applied: A9, A11 Date: 07/23/2012 Location(s): Haiti Offices(s): Golden Field Office

62

Control and Intervention of Cholera Outbreaks in Refugee Camps  

E-Print Network [OSTI]

associated with epidemic in Hispaniola. Emergency Infectionscholera outbreaks in Hispaniola (Haiti and the Dominicanepidemic in the island of HispaniolaHaiti and the Dominican

Sim, Christianna

2013-01-01T23:59:59.000Z

63

Democracy as a Human Right: Raymond Joseph, Despotic Haiti, and the Translation of a Rights Discourse, 19651969  

E-Print Network [OSTI]

Ibid, p. 97. See also Amartya Sen, Development as Freedom (emerges a precursor to Amartya Sens notion of capability

Polyn, Millery

2013-01-01T23:59:59.000Z

64

Foundations on Sand: An Analysis of the First U.S. Occupation of Haiti, 1915-1934  

E-Print Network [OSTI]

of Haitian Studies Occasional Papers Bryant C. Freeman, Ph.D. - Series Editor N 1 - Konstitisvon Repiblik Ayiti, 29 mas 1987. 1994. Pp. vi-106. Haitian-language version (official orthography) of the present Constitution, as translated by Paul Dejean...

Bunce, Peter L.

2003-01-01T23:59:59.000Z

65

OAiC RiDGE NATIONAL LABORAl-ORY LKCKKBSP HAITI MANA%ED AND OPERATED BY  

Office of Legacy Management (LM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment ofDepartment ofof EnergyYou$0.C. 20545*.MSE Cores" _ ,' ,:.'' , /v-i

66

A comparison of perceived effectiveness of technology projects from viewpoints of external nongovernmental organizations and host country beneficiaries in Haiti  

E-Print Network [OSTI]

of the Study. Objectives. . . . . Theoretical Base Hypothesis. Delimitations. Limitations. Basic Assumptions. . II REVIEW OF LITERATURE. . . . . 1 3 3 3 6 6 6 7 III METHOD OF INVESTIGATION. 12 Sample Selection. Sampling Method. . Instrument..., Catholic Relief Services, and others initiate projects as "donors" within "host countries. " Many of these organizations are nongovernmental organizations (NGOs). They undertake these projects with the intent of fulfilling various aspects...

May, Donald Ray

1998-01-01T23:59:59.000Z

67

Florida Arbovirus Surveillance Week 23: June 3-9, 2012  

E-Print Network [OSTI]

, Ecuador, Ghana, Guyana, Haiti (4), Jamaica, Mexico, Suriname, and Turks & Caicos. Counties reporting cases

Watson, Craig A.

68

Parallel worlds: empirical region and place  

E-Print Network [OSTI]

vegetation dynamics in Hispaniola: a comparison of Haiti andunits. The exceptions, Hispaniola and Saint Martin, are

Ford, Of The

2013-01-01T23:59:59.000Z

69

Department of African Languages and Literature University of Wisconsin-Madison  

E-Print Network [OSTI]

, Venezuela, Cuba, Trinidad, Tobago, Puerto Rico, and Haiti. Yoruba is of significant interest to linguists

Wisconsin at Madison, University of

70

RasMol v2.5 A Molecular Visualisation Program  

E-Print Network [OSTI]

Incorporated. Alchemy and Sybyl are trademarks of Tripos Associates Inc. VAX is a trademark of Digital&S workstations, DEC Alpha (OSF/1, OpenVMS and Windows NT), IBM RS/6000, Cray, Sequent, VAX VMS (under DEC windows

Meagher, Mary

71

activated h-ras-1 oncogene: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary: recently demonstrated that the oncogenic, constitutively kinase activated NPM-ALK protein was antiapoptotic identified as part of the NPM-ALK oncogenic fusion...

72

Introduction The kinase Raf is a key target of the Ras GTPase during both  

E-Print Network [OSTI]

substrates (Sontag et al., 1993; Alessi et al., 1995; Wassarman et al., 1996; Maixner et al., 1998; Ugi et al

Baillie, David

73

FLI-1 Flightless-1 and LET-60 Ras control germ line morphogenesis in C. elegans  

E-Print Network [OSTI]

Background: In the C. elegans germ line, syncytial germ line nuclei are arranged at the cortex of the germ line as they exit mitosis and enter meiosis, forming a nucleus-free core of germ line cytoplasm called the rachis. ...

Lu, Jiamiao; Dentler, William L., Jr; Lundquist, Erik A.

2008-05-16T23:59:59.000Z

74

Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis  

E-Print Network [OSTI]

wells containing either 40 ng/ml SDF-1 con- ditioned mediumor control medium lacking SDF-1 and incubated for 22 hours.and grown in the presence of SDF-1 (the ligand for the CXCR4

2010-01-01T23:59:59.000Z

75

1. PMU Based RAS for a Hybrid AC/DC System 1.1. Project Team  

E-Print Network [OSTI]

to minimize the impact of disturbances. It is also an integration of various areas related to CPS these wide area protection schemes. Such schemes are essential to the strategic plan in enabling robustness

Li, Husheng

76

Wild Rose SFH DNR's largest facility Total Replacement Project Engineering Study RAS Intensive Rearing  

E-Print Network [OSTI]

liquid oxygen tank #12;Remote controls for production wells in coldwater headtank building (HDR Senior 2,400 gpm 75 deg F 2-Stage Water Heating Heat Recovery Finish Heating #12;Moving Bed Biofilter & K1

77

Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras  

E-Print Network [OSTI]

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human malignancies. To investigate the cellular origin(s) of this cancer, we determined the effect of PDAC-relevant gene mutations in distinct cell types ...

Friedlander, Sharon Y. Gidekel

78

Improvement of kiln design and combustion/carbonization timing to produce charcoal from agricultural waste in Developing countries  

E-Print Network [OSTI]

Current economic conditions in third world countries like Haiti are so poor that the majority of the population has no access to energy sources that people in the first world take for granted. In Haiti the last two percent ...

Martinez, Jason A. (Jason Alexander)

2006-01-01T23:59:59.000Z

79

SIT Workshops 1995 2011 Page 1 of 17  

E-Print Network [OSTI]

Guyana Haiti Jamaica Saint Kitts and Nevis Saint Lucia Suriname Trinidad & Tobago 12. US-India Workshop

80

Are you interested in opportunities with the  

E-Print Network [OSTI]

, the Democratic Republic of Congo (Zaire), the Philippines, Romania, Haiti and ­ most recently ­ Senegal where he

Roy, Subrata

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Ethiopia and Eritrea During the Scramble for Africa: A Political Biography of Ras Alul, 1875-1897  

E-Print Network [OSTI]

and Faber, London, 1974. Ethiopia and Eritrea During thediplomatic and military history of contemporary Ethiopia.this crucial juncture, Ethiopia faced three well organized

Demissie, Fassil

1983-01-01T23:59:59.000Z

82

E-Print Network 3.0 - algeria cuba indonesia Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Guinea Guinea Bissau Guyana Haiti Afghanistan Albania Algeria Andorra Romania Russia Rwanda Samoa... Honduras Hungary Iceland India Indonesia Angola Antigua Argentina...

83

E-Print Network 3.0 - algeria bangladesh egypt Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Guinea Guinea Bissau Guyana Haiti Afghanistan Albania Algeria Andorra Romania Russia Rwanda Samoa... Sinapore Slovakia Jamaica Japan Jordan Kazakstan Kenya Bangladesh...

84

E-Print Network 3.0 - algeria bangladesh cuba Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Guinea Guinea Bissau Guyana Haiti Afghanistan Albania Algeria Andorra Romania Russia Rwanda Samoa... Sinapore Slovakia Jamaica Japan Jordan Kazakstan Kenya Bangladesh...

85

E-Print Network 3.0 - algeria australia austria Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Guinea Guinea Bissau Guyana Haiti Afghanistan Albania Algeria Andorra Romania Russia Rwanda Samoa Source: Alechina, Natasha - School of Computer Science, University of...

86

Parallel worlds: empirical region and place  

E-Print Network [OSTI]

Western) Guyana. - Suriname. - Brazil. - Bolivia. - Chile.intelligible except those of Suriname. Holm cites EdwardGuyana, Haiti, Jamaica, Suriname, and Trinidad and Tobago,

Ford, Of The

2013-01-01T23:59:59.000Z

87

International Student and Scholar Enrollment & Statistical Report  

E-Print Network [OSTI]

SURINAME 1 GUATEMALA AND36 SWAZIL 1 GUYANA 1 SWEDEN 16 HAITI 2 SWITZERLAND 2 HONDURAS 9 SYRIA 1 HONG KONG

Ginzel, Matthew

88

International Student and Scholar Enrollment & Statistical Report  

E-Print Network [OSTI]

SURINAM 1 GHANA 12 SWAZILAND 2 GREECE 21 SWEDEN 14 GUATEMALA ND22 SWITZERLA 6 GUYANA 1 SYRIA 1 HAITI 2

Ginzel, Matthew

89

E-Print Network 3.0 - asmara district eritrea Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

1, 2011) Summary: Colombia East Timor Eritrea Ethiopia Haiti Iran Iraq - Kurdish Region Ivory Coast Lebanon Libya Saudi Source: Warkentin, Ian G. - Department of Biology, Memorial...

90

Protecting Environmentally-Sensitive Areas and Promoting Tourism in "The Back Patio of the United States:" Thoughts about Shared Responsibilities in Ecosystem and Biodiversity Protection  

E-Print Network [OSTI]

1/3 of the island of Hispaniola, namely Haiti, nearly 90% ofonly on the island of Hispaniola, has been in existence for

Crawford, Colin

2006-01-01T23:59:59.000Z

91

Imagining Cultures: The Transnational Imaginary in Postrace America  

E-Print Network [OSTI]

arrival of Europeans on Hispaniola unleashed the fuk on thesister-nation on the island of Hispaniola, Haiti, fuk is a

Saldvar, Ramn

2012-01-01T23:59:59.000Z

92

Studying Fictional Representations of History in the L2 Classroom  

E-Print Network [OSTI]

of Haiti or the island of Hispaniola. In less than a week ofWar and the island of Hispaniola during the terror of

Tegmark, Mats

2012-01-01T23:59:59.000Z

93

Systematics and Ethnobotany of Salvia Subgenus Calosphace and Origins of the Hallucinogenic Sage, Salvia divinorum  

E-Print Network [OSTI]

endemic to the island of Hispaniola (10 spp), for which weupon the islands of Hispaniola (Haiti and the Dominicanendemic to the island of Hispaniola. Staminal Evolution in

Jenks, Aaron Allon

2008-01-01T23:59:59.000Z

94

Volunteer Day Countries Represented  

E-Print Network [OSTI]

Haiti Iran Korea Kuwait Russia Saudi Arabia Spain Taiwan Turkey Venezuela Vietnam Manners and Culture Q's warm-weather fashion, and we have a lot of warm w

Pilyugin, Sergei S.

95

Humanity Must Be Defended: War, Politics and Humanitarian Relief in Iraq, 1990-2004  

E-Print Network [OSTI]

Haiti, Somalia, Iraqi Kurdistan and Cambodia. A few oldprovinces into Iraqi Kurdistan in the wake of Operationsometimes called Iraqi Kurdistan). The NGO representatives

McIntyre, Adrian

2010-01-01T23:59:59.000Z

96

SAFETY SERIES No.75-INSAG-4 INTERNATIONAL ATOMIC ENERGY AGENCY...  

Broader source: Energy.gov (indexed) [DOE]

DENMARK DOMINICAN REPUBLIC ECUADOR EGYPT EL SALVADOR ETHIOPIA FINLAND FRANCE GABON GERMANY GHANA GREECE GUATEMALA HAITI HOLY SEE HUNGARY ICELAND INDIA INDONESIA IRAN, ISLAMIC...

97

DEVELOPING SAFETY CULTURE IN NUCLEAR ACTIVITIES Practical Suggestions  

Broader source: Energy.gov (indexed) [DOE]

REPUBLIC ECUADOR EGYPT EL SALVADOR ESTONIA ETHIOPIA FINLAND FRANCE GABON GEORGIA GERMANY GHANA GREECE GUATEMALA HAITI HOLY SEE HUNGARY ICELAND INDIA INDONESIA IRAN, ISLAMIC...

98

Readout of Secretary Chu's Bilateral Meetings at the Energy and...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

The United States appreciates the major commitments that Venezuela has made to help the people of Haiti recover, including ensuring the continued operation of critical power...

99

The Fear of French Negroes: Transcolonial Collaboration in the Revolutionary Americas  

E-Print Network [OSTI]

as Santiago de Cuba, Tampico, Campeche, the Floridas, Haiti,his followers had named Campeche, Laffite writes, Everyone15152 calypso, 156 Campeche, Mexico, 98 Campos Tavres,

Johnson, Sara E.

2012-01-01T23:59:59.000Z

100

President Obama Announces More Key Administration Posts | Department...  

Broader source: Energy.gov (indexed) [DOE]

as Russia, Zimbabwe, Iran, Cuba, China, Uganda, Haiti, the Philippines, El Salvador and Egypt. He also has been actively involved in promoting the rights of refugees and displaced...

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

CI-OFF Ex A (Rev. 0.2, 4/9/13) Exhibit A General Conditions  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Democratic Republic of Congo, Djibouti, East Timor, Equatorial Guinea, Eritrea, Ethiopia, Gambia, Guinea, Guinea-Bissau, Haiti, Kiribati, Laos, Lesotho, Liberia, Madagascar,...

102

NCIPO Ex A (Rev. 2.1, 4/9/13) Exhibit A General Conditions  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Democratic Republic of Congo, Djibouti, East Timor, Equatorial Guinea, Eritrea, Ethiopia, Gambia, Guinea, Guinea-Bissau, Haiti, Kiribati, Laos, Lesotho, Liberia, Madagascar,...

103

CHARLES WESLEY WOOD BIOGRAPHICAL SKETCH (http://www.linkedin.com/pub/wes-wood/71/499/230)  

E-Print Network [OSTI]

, Thailand, Honduras, Mexico, The Philippines, Haiti, and New Zealand. Wes served as Associate Editor Program. Consulting projects have included revegetation of coal mine refuse; monitoring nitrate movement

Jawitz, James W.

104

The Fogarty Scholars Experience: Where research training meets the world  

E-Print Network [OSTI]

. Current locations include Bangladesh, Botswana, Brazil, China, Haiti, India, Kenya, Malawi, Mali, Peru experiences at NIH-supported research centers in resource-limited settings. Program administration provided

Rhode Island, University of

105

E-Print Network 3.0 - allergy current research Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

at top-ranked, NIH-funded research centers abroad... . Current locations include Bangladesh, Botswana, Brazil, China, Haiti, India, Kenya, Malawi, Mali, Peru Source: Rhode...

106

Uganda Manafwa River early flood warning system development hydrologic watershed modeling using HEC-HMS, HEC-RAS, ArcGIS  

E-Print Network [OSTI]

The Manafwa River basin spans several districts in Eastern Uganda. Over the years, frequent floods have constantly posed a great threat to the local communities in these districts. The Uganda Red Cross Society (URCS) intends ...

Ma, Yan, M. Eng. Massachusetts Institute of Technology

2013-01-01T23:59:59.000Z

107

Tissue-specific interactions between oncogenic K-ras and the p19A?r?f?_p53 pathway determine susceptibility to transformation  

E-Print Network [OSTI]

Tumor development is a multi-step process driven by the collective action of gain-of-function mutations in oncogenes and loss-of-function alterations in tumor suppressor genes. The particular spectrum of mutations in a ...

Young, Nathan Price

2010-01-01T23:59:59.000Z

108

Constitutively Active Rap2 Transgenic Mice Display Fewer Dendritic Spines, Reduced Extracellular Signal-Regulated Kinase Signaling, Enhanced Long-Term Depression, and Impaired Spatial Learning and Fear Extinction  

E-Print Network [OSTI]

Within the Ras superfamily of GTPases, Rap1 and Rap2 are the closest homologs to Ras. In non-neural cells, Rap signaling can antagonize Ras signaling. In neurons, Rap also seems to oppose Ras in terms of synaptic function. ...

Ryu, Jubin

109

Registration Guide for the Fall Semester 2014-2015 Classes begin on Wednesday, September 3, 2014  

E-Print Network [OSTI]

, 2014 Ras Beirut branches of: Arab Bank, Bank Audi, Bank Mediterranee, HSBC, BLOM, and Western Union

Shihadeh, Alan

110

E-Print Network 3.0 - arabia senegal sudan Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Country: Alumni Country: Alumni Country: Alumni Summary: Austria 31 Guatemala 8 Russia 14 Bahamas 13 Haiti 4 Rwanda 1 Bangladesh 17 Honduras 3 Saudi Arabia 13... Barbados 3...

111

Malaria resurgence: a systematic review and assessment of its causes  

E-Print Network [OSTI]

for the; 2002. 134. PAHO: Suriname. Cartagena, Colombia: The1996 [131] Costa Rica Belize Suriname Ecuador Panama PacificNi Nicaragua P Peru Suriname P Panama Mexico Haiti Guyana

2012-01-01T23:59:59.000Z

112

Strategic relational communication in crisis : the humanitarian example  

E-Print Network [OSTI]

The discourse on Haiti is both vast and varied with public attention soaring when an earthquake hit the island in January 2010. Many questions have since been raised by global stakeholders as to how the situation was ...

Michaels, Olufunke

2013-01-01T23:59:59.000Z

113

Women playing a man's game : reconstructing ceremonial and ritual history of the Mesoamerican ballgame  

E-Print Network [OSTI]

that included La Hispaniola and El Rio de Orinoco inOrinoco (Venezuela) and La Hispaniola (Haiti). The earliesta Taino game in 1525 at La Hispaniola that was also called

Ramos, Maria Isabel

2012-01-01T23:59:59.000Z

114

RESEARCH ARTICLE Phylogeography and conservation of the endemic Hispaniolan  

E-Print Network [OSTI]

the Tiburon Peninsula's single primary forest reserve. Keywords Phaenicophilus Á Palm-Tanager Á Hispaniola Á Haiti Á Island Á Phylogeography Introduction Hispaniola, which supports more endemic bird species than

Townsend, Andrea

115

Phytologia (April 2008) 90(1) 103 THE EVOLUTION OF CARIBBEAN JUNIPERUS  

E-Print Network [OSTI]

, Cuba, Jamaica, likely extinct in Haiti), J. gracilior (endemic to Hispaniola), J. gracilior var. ekmanii (Florin) R. P. Adams (endemic to Hispaniola), J. gracilior var. urbaniana Pilger & Ekman) R. P

Adams, Robert P.

116

The feasibility of malaria elimination  

E-Print Network [OSTI]

The feasibility of malaria elimination on the island of Hispaniola, with a focus on Haiti........................................................................................................15 Malaria on the island of Hispaniola: context..........................................................................................17 Malaria on the island of Hispaniola: history of the response

Klein, Ophir

117

UNIVERSIT DEGLI STUDI La cooperazione internazionaLe  

E-Print Network [OSTI]

DELLA LUCE (Togo) AQUAPLUS - Acqua Energia per la Vita (Haiti) Lotta integrata al fitoplasma delle dei codici normalizzati OCSE per le prove dei trattori agricoli e forestali (Brasile) Biotecnologia da

De Cindio, Fiorella

118

Volume 130, Number 2 tech.mit.edu Friday, February 5, 2010 Oldest and Largest  

E-Print Network [OSTI]

skating event in the Johnson Ice Rink, where students gathered to brainstorm relief project ideas and the student-organized Haiti Re- lief Show, the MIT Chapter of Global Poverty Initiative held a charity ice

Ishii, Hiroshi

119

The UNIVERSITY of NORTH CAROLINA at CHARLOTTE An Equal Opportunity/Affirmative Action Employer  

E-Print Network [OSTI]

, Iran, Iraq, Lebanon, Former Liberian Regime of Charles Taylor, Libya, North Korea, Somalia, Sudan, Afghanistan, Democratic Republic of the Congo, Haiti, Libya, Vietnam, Somalia, and Sri Lanka. Please contact

Howitt, Ivan

120

Design of a crushing and agglomeration process for manufacturing bagasse charcoal  

E-Print Network [OSTI]

In Haiti, wood and wood charcoal are common fuels for cooking. This practice has contributed to deforestation, leading to erosion and fatal floods. The availability of charcoal made from a different source other than wood, ...

Fan, Victoria Y. (Victoria Yue-May)

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

In Leake, D., ed., 1996, Case-Based Reasoning: Experiences, Lessons, and Future Directions. Menlo Park: AAAI Press MIT Press, 1996.  

E-Print Network [OSTI]

in Bosnia, in Somalia, in Haiti. Ed Timms, Dallas Morning News Windows 95: Microsoft's Vietnam? Headline plan. The commentators who apply lessons of Vietnam to Bosnia, however, must do more subtle reasoning

Leake, David B.

122

E-Print Network 3.0 - alos satellite imagery Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3 12;4 Disaster Monitoring (Earthquake in Haiti, Jan 2010) ALOS AVNIR-2 ALOS PALSAR... Wind, SST , Water vapor Phase B Precipitation CO2, Methane GCOM-W2 GOSAT-2 ALOS-3...

123

Literacy Assessment Using  

E-Print Network [OSTI]

in Haiti is insufficient and doesn't give policy makers information to make and national ministries to optimize support. Globally, India and the east government and funder's policy actions. Such a model also aligns

Qian, Ning

124

Third-world folk beliefs and practices: Haitian medical anthropology  

E-Print Network [OSTI]

Voodoo Possession Wakes Water Weaning Western Medicine Wheelchair Whooping Cough Wi Womb Worms Wounds Yawning Yaws Zombis Appendix - 100 Haitian Proverbs on Health and Sickness: Aging Birthing Death Diet Eyes Forbearance Health... often causes the accident to be seen as having definitely been caused by a Voodoo-inspired curse. 13 ACHIEVEMENTS Notable medical advances in recent times in Haiti: eradication of yaws, yellow fever, and smallpox. Haiti has also become...

Freeman, Bryant C.

1998-01-01T23:59:59.000Z

125

Chapter 1 Purpose of and Need for Action  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

For the SOA path, BPA and other utilities have developed a non-wires measure called a remedial action scheme (RAS) that is carried out when needed. RAS uses a high-speed...

126

We constructed a simple mathematical model to examine the relative effectiveness  

E-Print Network [OSTI]

expression construct pFBE (10). tRe-Ras64BV12 was constructed by cloning the Ras64BV12 cDNA as an Eco RI

Desplan, Claude

127

Radiologist Assistant Professional Curriculum  

E-Print Network [OSTI]

Rotation Breast Imaging * Clinical Rotation Pediatric Radiology * Clinical Rotation Nuclear Medicine. RAS 7310 Radiologist Mentored Experience I 1 cr. Semester Total Credits: 10 RAS 7610 Radiologic. * Clinical Rotation Gastrointestinal Radiology * Clinical Rotation General Diagnostic Radiology * Clinical

Berdichevsky, Victor

128

E-Print Network 3.0 - application onleading hec Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

to assess its... capability in the U.S. Army Corps of Engineering HEC-RAS public domain software to the application... . Furthermore, this application of HEC-RAS to the Peace ......

129

Differentiation Self-renewal  

E-Print Network [OSTI]

Off state Ras Ras­GAP PI3K ERK1 ERK2 Differentiation SC1 SC1 Self-renewal Ras On state GDP GTP N NN the kinase enzyme Figure 1 | Chemically induced stem-cell self-renewal. Chen et al.2 have discovered, which promotes stem-cell self-renewal. Activated Ras also switches on the enzymes ERK1 and ERK2, which

Glyde, Henry R.

130

American University of Beirut Application for  

E-Print Network [OSTI]

to the applicant's name, to HSBC Bank Ras Beirut Branch, Bank Swift Code BBMELBBX, Bank Routing Number: 0070031

Shihadeh, Alan

131

Large Magnetoresistanceof a Dilute 2DHG in p-Si/SiGe/Si in a...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

F. Ioffe Physico-Technical Institute, RAS, 194021 St. Petersburg, Russia National High Magnetic Field Laboratory, Tallahassee, Florida 32310, USA Warwick SEMINANO, University of...

132

The dynamic interplay between adhesion signaling and the ERK MAP kinase pathway  

E-Print Network [OSTI]

Cancer Lett 149, 105-113. Ugi, S. , Imamura, T. , Ricketts,and the activation of Ras (Ugi et al. , 2002). A necessary

Haling, Jacob Robert

2010-01-01T23:59:59.000Z

133

Breaking a Pocket of Resistance in the Fight Against Cancer  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Rat Sarcoma, is a nucleotide binding protein that responds to chemical signals (nucleotides). When in the "on" state, RAS activates other proteins, resulting in a cascade of...

134

E-Print Network 3.0 - apoptosis limits dna Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

germ cell apoptosis... RasMAP-kinase signaling. CEP-1-dependent ... Source: Blackwell, Keith - Harvard University; Gartner, Anton - Wellcome Trust Centre for Gene Expression and...

135

10th International Conference on Chemometrics in Analytical Chemistry CHEMOMETRICS IN THE TROPICS  

E-Print Network [OSTI]

Russian: http://rcs.chph.ras.ru/rcsin.htm -in Croatian: http://www: Afrikaans: CHEMOMETRIE CHEMO- + -METRIE (60-90%) CHEMOMETRIKE CHEMO- + -METRIKA (10-40%) Croatian

Ferreira, Mrcia M. C.

136

E-Print Network 3.0 - anatomy pathophysiology neuroradiology...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Anatomy for Physician Assistants I PAS 7001 Anatomy for Physician Assistants Lab PAS 7070 Health Care... Issues PAS 7500 Pathophysiology RAS 7400 Patient Assessment Semester Total...

137

Supervisory Interdisciplinary Engineer (TECR)  

Broader source: Energy.gov [DOE]

This position provides leadership, monitoring, and technical expertise for the development, engineering, design, and implementation of RAS (Remedial Action Scheme) systems, data acquisition systems...

138

Molecular Ecology (2008) 17, 598610 doi: 10.1111/j.1365-294X.2007.03595.x 2007 The Authors  

E-Print Network [OSTI]

Quaternary climate change had a strong impact on the geographical distribution and demographic history Ecology, Ural Division of RAS, Yekaterinburg, Russia, World Museum of Mammoth, Yakutsk 677007, Russia

139

E-Print Network 3.0 - activate store-operated calcium Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Synaptic Summary: by Calcium Ions; is Activated by Ras-GTP All PLC Isoforms Perform the Same Reaction... Calcium Ions Play a Role in Muscle...

140

E-Print Network 3.0 - activity calcium signaling Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Calcium Levels... by Calcium Ions; is Activated by Ras-GTP All PLC Isoforms Perform the Same Reaction... Calcium Ions Play a Role in Muscle...

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

E-Print Network 3.0 - activates cyclic-amp response Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Receptor Mediated by Cyclic AMP and Summary: -coupled receptors can stimulate PLC- , apparently via formation of cyclic AMP and activation of the Ras- related... of PLC-...

142

S68 JUNE 2006| d. Central America and the Caribbean--E. K. Grover-Kopec31  

E-Print Network [OSTI]

S68 JUNE 2006| d. Central America and the Caribbean--E. K. Grover-Kopec31 I) TEMPERATURE Annual in the Caribbean, particularly in Jamaica, eastern Cuba, and western Haiti. Drought conditions, which have had of the Caribbean and Central American region is bimodal, with relative maxima occurring in May­June and September

143

STRATEGIC FOCUS: Sustainable Systems  

E-Print Network [OSTI]

to apply sustain- ability principles to building and design, transportation and other fields, to green, presented an ecologically-sustainable sanitation system developed for a small hospital in northern Haiti1010 STRATEGIC FOCUS: Sustainable Systems Biology doctoral student Tanya Lubansky uses quan

144

Croissance dmographique, pression foncire et insertion territoriale par les abattis en Guyane franaise  

E-Print Network [OSTI]

(Suriname, Brésil, Haïti, etc.). L'augmentation continue de la population entraîne une pression foncière et provenance notamment du Suriname s'appuient sur les abattis pour avoir un ancrage territorial afin de s neighbours (Surinam, Brazil, Haiti, etc). The continuous increase of population involves land pressure since

Boyer, Edmond

145

A NEW SPECIES OF MATELEA (APOCYNACEAE: ASCLEPIADOIDEAE) FROM HISPANIOLA  

E-Print Network [OSTI]

A NEW SPECIES OF MATELEA (APOCYNACEAE: ASCLEPIADOIDEAE) FROM HISPANIOLA Alexander Krings Herbarium_Krings@ncsu.edu ABSTRACT A new species of Matelea is described from Hispaniola, resulting from study of subtribe Hispaniola: Matelea pentactina Krings, sp. nov. (Fig. 1, A­B, E). TYPE: HAITI: Les Roseaux, Massif de la

Krings, Alexander

146

LETTERS | FOCUS PUBLISHED ONLINE: 24 OCTOBER 2010 | DOI: 10.1038/NGEO992  

E-Print Network [OSTI]

. This result is consistent with the long-term pattern of strain accumulation in Hispaniola. The unexpected.0 Haiti earthquake of 12 January 2010 is the largest event to strike the southern part of Hispaniola since yr-1 relative to the North American plate3,10 , implying oblique convergence between Hispaniola

Freed, Andrew

147

Phyllonycteris poeyi (Chiroptera: Phyllostomidae) CARLOS A. MANCINA  

E-Print Network [OSTI]

is endemic to the Greater Antilles and P. poeyi is endemic to Cuba and Hispaniola. P. poeyi is characterized and Natural Resources. DOI: 10.1644/852.1. Key words: Antilles, bat, Cuba, Cuban flower bat, Hispaniola-Recent skulls collected on Haiti (Hispaniola); he also differentiated Fig. 1.--Adult female Phyllonycteris poeyi

Hayssen, Virginia

148

Demographic and Social Predictors of Intimate Partner Violence in Colombia  

E-Print Network [OSTI]

Demographic and Social Predictors of Intimate Partner Violence in Colombia A Dyadic Power, and Colombia (Flake and Forste 2006). In Peru, low educational attainment and early union formation increase-dominant decision-making was associated with higher risk of IPV in Nicaragua, Haiti, and Colombia. The welter

Jones, James Holland

149

UNIVERSIT DEGLI STUDI tHe activities oF internationaL  

E-Print Network [OSTI]

's methodology of intervention in support of the cooperation (Sali) The cooperation is a challenge for the young people (Cinquanta) agriculture The strategies for the agricultural development (Bocchi) Project CITY OF LIGHT (Togo) AQUAPLUS - Water, Energy for Life (haiti) Integrated fight against the Phytoplasma

De Cindio, Fiorella

150

o encourage students to apply class-room learning and social responsibility  

E-Print Network [OSTI]

to Haiti to help earthquake victims. Another project converted a gas-powered vehicle into a gas-electric an autonomous electronic interface to facilitate three­way power flows between the electric vehicles, the solar in a home to generate electricity converted from the wind, ultimately reducing residential power costs

Wu, Shin-Tson

151

Accommodation & Accommodation & Commercial Services  

E-Print Network [OSTI]

is plumbed into the mains water supply, fed through a purification system and then decanted into branded in desperate need. Drop4drop provided funding for water purification kits, which were sent out to Haiti in the first instance to help with the shortage of clean drinking water. Each kit contained water purification

Oakley, Jeremy

152

Peacekeepers' Sex Scandals Linger, On Screen By NEIL MacFARQUHAR, 7 September 2011  

E-Print Network [OSTI]

senior United Nations officials in Bosnia are arguing about firing Kathy Bolkovac, an American police, a string of sex scandals from Bosnia to the Democratic Republic of Congo to Haiti involving peacekeeping in Bosnia. But Ms. Bolkovac says she has never been hired by another peacekeeping mission. (DynCorp issued

153

Effectiveness of a sports-based HIV prevention intervention in the Dominican Republic: a quasi-experimental study  

E-Print Network [OSTI]

Effectiveness of a sports-based HIV prevention intervention in the Dominican Republic: a quasi, and strenuous efforts to minimize loss-to-follow-up. Keywords: HIV; youth; sport; Dominican Republic; Caribbean living in Haiti and the Dominican Republic (DR) (PAHO, 2007; UNAIDS, 2008). In recent years, national

Vermont, University of

154

The effect of phosphorus on nitrogen fixation in three genotypes of cowpea (Vigna unguiculata (L.) Walp.)  

E-Print Network [OSTI]

. L, Cheaney, M. Taylor, M. C. Fuqua, and M. Villanueva. I am grateful to the concerned officials of the Departement de I'Agriculture, des Ressources Naturelles et du Developpement Rural of the Republic of Haiti for selecting me as the recipient...

Prophete, Emmanuel Hugues

1984-01-01T23:59:59.000Z

155

Saint Vincent and the Grenadines-Pilot Program for Climate Resilience...  

Open Energy Info (EERE)

Resilience (PPCR)1 Contents 1 Overview 2 Programs by Country 2.1 Bangladesh 2.2 Bolivia 2.3 Cambodia 2.4 Dominica 2.5 Grenada 2.6 Haiti 2.7 Jamaica 2.8 Mozambique 2.9 Nepal...

156

Asian Forum for Accelerators and Detectors 25 -26 February, 2013, Budker INP, Novosibirsk, Russia  

E-Print Network [OSTI]

, Russia 4th Asian Forum for Accelerators and Detectors (AFAD'13) will be hosted by Budker Institute of Nuclear Physics SB RAS, Novosibirsk, Russia, from February 25 to February 26, 2013. AFAD is the new name INP SB RAS, Lavrentiev av. 11, Novosibirsk 630090 Russia Meeting Web-site: http

157

Feb. 11, 2008 Advanced Fault Tolerance Solutions for High Performance Computing 1/47 Advanced Fault Tolerance Solutions  

E-Print Network [OSTI]

Feb. 11, 2008 Advanced Fault Tolerance Solutions for High Performance Computing 1/47 RAS RAS Advanced Fault Tolerance Solutions for High Performance Computing Christian Engelmann Oak Ridge National Solutions for High Performance Computing 2/47 · Nation's largest energy laboratory · Nation's largest

Engelmann, Christian

158

Ris-R-1240(EN) Isolated Systems with Wind Power  

E-Print Network [OSTI]

: Residential Area 9 Ras Sudr 9 Wadi Tal 10 2.4 Data screening 10 Hurghada: 3 Corner Village Hotel 10 Hurghada: 3 Corner Shopping Mall 23 Hurghada: Residential Area 36 Ras Sudr 48 Wadi Tal 61 3 Analysis of data

159

Quaternary Science Reviews 24 (2005) 533569 New insights into the Weichselian environment and climate of the  

E-Print Network [OSTI]

. The Bykovsky record shows how climate change, and the Last Glacial Maximum in particular, affected terrestrial and climate of the East Siberian Arctic, derived from fossil insects, plants, and mammals$ A.V. Shera,?, S Academy of Sciences (RAS), 33 Leninskiy Prospect, 119071 Moscow, Russia b Paleontological Institute, RAS

Ingólfsson, ?lafur

160

Liaison activities with the Institute of Physcial Chemistry of the Russian Academy of Sciences: Midyear report  

SciTech Connect (OSTI)

The task `IPC/RAS Liaison and Tank Waste Testing` is a program being conducted in fiscal year (FY) 1996 with the support of the U.S. Department of Energy (DOE) Office of Science and Technology, EM-53 Efficient Separations and Processing (ESP) Crosscutting Program, under the technical task plan (TTP) RLA6C342. The principal investigator is Cal Delegard of the Westinghouse Hanford Company. The task involves a technical liaison with the Institute of Physical Chemistry of the Russian Academy of Sciences (IPC/RAS) and their DOE-supported investigations into the fundamental and applied chemistry of the transuranium elements (primarily neptunium, plutonium, and americium) and technetium in @ine media. The task has three purposes: 1. Providing technical information and technical direction to the IPC/RAS. 2. Disseminating IPC/RAS data and information to the DOE technical community. 3. Verifying IPC/RAS results through laboratory testing and comparison with published data.

Delegard, C.H.

1996-05-29T23:59:59.000Z

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Workflow Behavior Auditing for Mission Centric Collaboration  

E-Print Network [OSTI]

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 6.2.2.3. Discovery Model Conformance . . . . . . . . . . . . . . . . . . . . . . . . . . 116 6.3. Structural Conformance with Timestamp Distortion . . . . . . . . . . . . . . . . . . 117 6.3.1. Footprint Matrix Conformance... and dispersing widely over the disaster area [10]. On January 12, 2010, the Haiti Earthquake initiated massive disaster relief 2 mission for DoD. Within a day, the US military was operating the Port-Au-Prince airport to coordinate relief efforts...

Pecarina, John Matthew

2013-10-25T23:59:59.000Z

162

South America, Central America, the Caribbean, and Mexico  

SciTech Connect (OSTI)

Summaries of oil and gas drillings, well completions, production, exploratory wells, exploration activity and wildcat drilling were given for South America, Central America, the Caribbean, and Mexico. The countries, islands, etc. included Argentina, Bahamas, Barbados, Belize, Bolivia, Brazil, Colombia, Costa Rica, Cuba, Dominican Republic, Ecuador, French Guiana, Guatemala, Guyana, Haiti, Honduras, Jamaica, Leeward and Windward Islands, Mexico, Netherlands Antilles, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, El Salvador, Surinam, Trinidad and Venezuela. 16 figures, 120 tables. (DP)

Deal, C.

1981-10-01T23:59:59.000Z

163

Halawa, Hawaii: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti: Energy

164

Hale County, Alabama: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti: Energy859102°,

165

Hale County, Texas: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti: Energy859102°,Hale

166

Haleakala Volcano Geothermal Area | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti:

167

Haleburg, Alabama: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti:Haleburg, Alabama:

168

Haleiwa, Hawaii: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti:Haleburg,

169

Halesite, New York: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: Energy Resources Jump to: navigation,Ohio:Greer County is a countyon State Highways |Haiti:Haleburg,Halesite,

170

Parallel Web Scripting with Reactive Constraints Thibaud Hottelier  

E-Print Network [OSTI]

Parallel Web Scripting with Reactive Constraints Thibaud Hottelier James Ide Doug Kimelman Ras Bodik Electrical Engineering and Computer Sciences University of California at Berkeley Technical Report to lists, requires prior specific permission. #12;Parallel Web Scripting with Reactive Constraints Thibaud

Bodik, Rastisla

171

Symmetric Active/Active High Availability for High-Performance Computing System Services  

E-Print Network [OSTI]

to understand problems, such as in climate dynam- ics, nuclear astrophysics, fusion energy, nanotechnology, and human genomics. Computer simulations of real-world and theoretical experiments exploiting multi software and scientific applications with respect to reliability, availability and serviceability (RAS

He, Xubin "Ben"

172

Order Module--DOE O 425.1D, VERIFICATION OF READINESS TO START...  

Broader source: Energy.gov (indexed) [DOE]

In the second section we will discuss 1) the requirements applicable to DOE ORRs and DOE RAs, and 2) the core requirements. In the third section we will discuss the 1)...

173

Identification of conserved chromatin-regulatory complexes among the class B synthetic multivulva proteins  

E-Print Network [OSTI]

The class A, B, and C synthetic Multivulva (synMuv) genes act redundantly to antagonize Ras-mediated vulval induction in C. elegans. Many of these genes encode proteins that are likely to function in transcriptional ...

Harrison, Melissa M

2006-01-01T23:59:59.000Z

174

Supporting Information Detailed Structure of the H2PO4  

E-Print Network [OSTI]

attacking water being necessary for hydrolysis. In total 28 atoms were described by the SCC with the CHARMM force field.12 The system for the substate GTP in the Ras·GAP was firstly pre-equilibrated for 500

Gerwert, Klaus

175

Information Systems 28 (2003) 241242 Special issue on data management in bioinformatics  

E-Print Network [OSTI]

, discusses the application of the array DBMS, RasDaMan, to the management of gene expression data in situ biological data, namely, the inherent complexity of biological data, domain knowledge barrier, the evolution

Zaki, Mohammed Javeed

176

Coordinated regulation by Shp2 tyrosine phosphatase of multiple signals controlling insulin biosynthesis in pancreatic beta-cells  

E-Print Network [OSTI]

mechanisms of the Helicobacter pylori CagA protein. Nat RevY. , et al. (2004). Helicobacter pylori CagA induces Ras-an intracellular target of Helicobacter pylori CagA protein.

Zhang, Sha

2008-01-01T23:59:59.000Z

177

Altered renal function and the development of angiotensin II-dependent hypertension  

E-Print Network [OSTI]

Inappropriate modulation of the renin angiotensin system (RAS) can lead to derangements of blood pressure homeostasis in humans. Cyp1a1-mRen2.F transgenic rats were used to define the renal mechanisms underlying the ...

Ashek, Ali

2011-07-05T23:59:59.000Z

178

Feasibility of Wholesale Electricity Competition in a Developing Country: Insights from Simulating a Market in Maharashtra State, India  

E-Print Network [OSTI]

India looking at 2 mt more LNG from RasGas. August 29 thhas planned for major LNG imports. Minimum flow constraintsbasis. Liquefied Natural Gas (LNG) Prices India is currently

Phadke, Amol

2007-01-01T23:59:59.000Z

179

Journal of Bioinformatics and Computational Biology Vol. 4, No. 2 (2006) 589596  

E-Print Network [OSTI]

. DANILOVA Institute for Problems of Information Transition RAS Bolshoi Karetnyi per. 19, Moscow, 127994 folding. 589 #12;590 L. V. Danilova et al. 1. Introduction RNA secondary structure prediction is a classic

Pervouchine, Dmitri D.

180

Office for Residential Life & Housing Services University of Rochester  

E-Print Network [OSTI]

Office for Residential Life & Housing Services University of Rochester RESIDENT ADVISOR POSITION DESCRIPTION Resident Advisors help build healthy and inclusive residential communities that complement and extend classroom learning. RAs are expected to create intellectually active residential environments

Cantlon, Jessica F.

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

684 NATURE PHYSICS | VOL 9 | NOVEMBER 2013 | www.nature.com/naturephysics Russian science in danger  

E-Print Network [OSTI]

President of the RAS, Vladimir E. Fortov, went to see the Russian President Vladimir V. Putin with a request to withdraw the bill. The answer was "no". After consultation with some other members of the Academy, Putin

Loss, Daniel

182

HER receptor-mediated dynamic signalling in breast cancer cells  

E-Print Network [OSTI]

The dynamics of cell signalling are critical to cell fate decisions. Human Epidermal growth factor Receptors (HERs)-mediated Ras/Raf/MEK/ERK and PI3K/Akt signalling cascades relay extracellular signals from the plasma ...

Hu, Huizhong

2011-07-05T23:59:59.000Z

183

Liaison activities with the institute of physical chemistry, Russian academy of sciences: FY 1996  

SciTech Connect (OSTI)

The task ``IPC/RAS Liaison and Tank Waste Testing`` is a program being conducted in fiscal year (FY) 1996 with the support of the U.S. Department of Energy (DOE) Office of Science and Technology, EM-53 Efficient Separations and Processing (ESP) Crosscutting Program, under the technical task plan RLA6C342. The principal investigator is Cal Delegard of the Westinghouse Hanford Company. The task involves a technical liaison with the Institute of Physical Chemistry of the Russian Academy of Sciences (IPC/RAS) and their DOE-supported investigations into the fundamental and applied chemistry of the transuranium elements (primarily neptunium, plutonium, and americium) and technetium in alkaline media. The task has three purposes: 1. Providing technical information and technical direction to the IPC/RAS. 2. Disseminating IPC/RAS data and information to the DOE technical community. 3. Verifying IPC/RAS results through laboratory testing and comparison with published data. This report fulfills the milestone ``Provide End-of-Year Report to Focus Area,`` due September 30, 1996.

Delegard, C.H.

1996-09-23T23:59:59.000Z

184

Ionospheric effects during first 2 hours after the Chelyabinsk meteorite impact  

E-Print Network [OSTI]

This paper presents the analysis of ionospheric effects in the region close to the Chelyabinsk meteorite explosion at 03:20UT 2013 February 15 from the Institute of Solar-Terrestrial Physics of Siberian Branch of Russian Academy of Sciences (ISTP SB RAS) EKB radar data, and from the Institute of Geophysics of Ural Branch of Russian Academy of Sciences (IG UB RAS) PARUS ionosonde data. Both instruments are located within the IG UB RAS Arti Observatory approximately 200 km northward from the estimated explosion site. According to the data obtained, the ionospheric disturbance caused by the meteorite flyby, explosion, and impact had high dynamics and amplitude. However, it obviously did not lead to a variation in the ionosphere mean parameters in the region above the disturbance center during the first 2 hours. Essential effects, however, were observed at more than 100-200 km from the explosion site and farther up to 1500 km.

Berngardt, O I; Zherebtsov, G A; Kusonski, O A; Grigorieva, S A

2013-01-01T23:59:59.000Z

185

Confirmation of intrinsic electron gap states at nonpolar GaN(1-100) surfaces combining photoelectron and surface optical spectroscopy  

SciTech Connect (OSTI)

The electronic structure of GaN(1100) surfaces is investigated in-situ by photoelectron spectroscopy (PES) and reflection anisotropy spectroscopy (RAS). Occupied surface states 3.1?eV below the Fermi energy are observed by PES, accompanied by surface optical transitions found in RAS around 3.3?eV, i.e., below the bulk band gap. These results indicate that the GaN(1100) surface band gap is smaller than the bulk one due to the existence of intra-gap states, in agreement with density functional theory calculations. Furthermore, the experiments demonstrate that RAS can be applied for optical surface studies of anisotropic crystals.

Himmerlich, M., E-mail: marcel.himmerlich@tu-ilmenau.de; Eisenhardt, A.; Shokhovets, S.; Krischok, S. [Institut fr Physik and Institut fr Mikro- und Nanotechnologien, TU Ilmenau, PF 100565, 98684 Ilmenau (Germany); Rthel, J.; Speiser, E.; Neumann, M. D.; Navarro-Quezada, A.; Esser, N. [Leibniz-Institut fr Analytische Wissenschaften - ISAS - e.V., Albert-Einstein-Strasse 9, 12489 Berlin (Germany)

2014-04-28T23:59:59.000Z

186

Refo?m nan Lajistis = Judicial reform  

E-Print Network [OSTI]

gen ase tribinal 2 Kdripsyon jij yo 2 Jij yo manke fmasyon 2 Lajistis ap mache kon tti 3 Kisa ki anpechc jij yo ft travay yo byen? 3 Sou kisa refm lajistis la dvve chita? 4 Poukisa refm administratif la enptan? . . . . 5 Poukisa dwe gen...-Language Books on Haiti. 1995 (Updated). Pp. 21. More than 150 entries, with brief description of each; special list of T o p Ten." Introduction and text in English. Updated periodically. No 4 - Strategy of Aristide Government for Social and Economic...

Seza, Mari Dyevela

1996-01-01T23:59:59.000Z

187

Si m pa rele: Annexes I et II, Si m pa rele: Annexe III  

E-Print Network [OSTI]

and text in English. Updated periodically. N 4 - Strategy of Aristide Government for Social and Economic Reconstruction (August 1994). 1994. Pp. iv-9. Official document setting forth recovery plan for Haiti. Introduction and text in English. N 5... Peyi Dayiti. 1995. Pp. v-71. Haitian-language version of N 5, in Pressoir-Faublas orthography. Introduction in English. N 7 - Samuel G. Perkins, "On the Margin of Vesuvius": Sketches of St. Domingo, 1785-1793. 1995. Pp. vi-75. First-hand account...

1998-01-01T23:59:59.000Z

188

Haitian-English Dictionary  

E-Print Network [OSTI]

.prop.n. inhabitant of Haut- Palmiste (Tortuga Island, Dept. North-West) palmye n. [Fr.] palm tree ~ a Iwil oil palm Palo prop.n. Palau (Western Pacific) paloud, palout n. clam (seafood) palpa conj. let alone, much less; even more, all the more palpab: prdv... to another) papiydt n. fine quality of paper (used in Haiti esp. in kite-making) papdt n. doorstep, threshold; doorway; front (of house) papou adj. full-feathered (bird); in need of a haircut paprika n. paprika (cf poud piman) papsis v. to fail, flop...

Freeman, Bryant C.

2010-01-01T23:59:59.000Z

189

1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLasDelivered‰PNG IHDR€ÍSolarReconstructionKathychangesimulate nanoscaleMimickinglightHaiti

190

Considerations for Contractile Electroactive Materials and Actuators  

SciTech Connect (OSTI)

Ras Labs produces electroactive polymer (EAP) based materials and actuators that bend, swell, ripple, and now contract (new development) with low electric input. In addition, Ras Labs produces EAP materials that quickly contract and expand, repeatedly, by reversing the polarity of the electric input. These recent developments are important attributes in the field of electroactivity because of the ability of contraction and contraction-expansion to produce biomimetric motion. The mechanism of contraction is not well understood. Radionuclide-labeled experiments were conducted to determine the mechanisms during contraction of these EAPs.

Lenore Rasmussen, David Schramm, Lewis D. Meixler, Charles A. Gentile, George Ascione, Carl Tilson, and Kelsey Pagdon

2010-02-19T23:59:59.000Z

191

Mon. Not. R. Astron. Soc. 000, 000000 (0000) Printed 4 July 2011 (MN LATEX style file v2.2) The SAURON Project -XIX. Optical and near-infrared scaling  

E-Print Network [OSTI]

galaxies J. Falc´on-Barroso,1,2,3 G. van de Ven,4,5 R. F. Peletier,6 M. Bureau,7 H. Jeong,8,9 R. Bacon,10 M of Astronomy, Yonsei University, Seoul 120-749, Korea 4 July 2011 c 0000 RAS #12;2 Falc´on-Barroso et al

Bureau, Martin

192

International Kimberlite Conference Long Abstract 1 CRATONIC CONDITIONS BENEATH ARKHANGELSK, RUSSIA  

E-Print Network [OSTI]

, RUSSIA: GARNET PERIDOTITES FROM THE GRIB KIMBERLITE Vladimir Malkovets1,2,3 , Lawrence Taylor2 , William , Konstantin Litasov6 1 Institute of Mineralogy and Petrography SB RAS, Russia; 2 Planetary Geoscience University, Australia; 4 Arkhangelskgeolrazvedka Ltd, Russia; 5 Arkhangelskgeoldobycha Ltd, Russia; 6

Taylor, Lawrence A.

193

The Astrophysical Journal, 757:92 (6pp), 2012 September 20 doi:10.1088/0004-637X/757/1/92 C 2012. The American Astronomical Society. All rights reserved. Printed in the U.S.A.  

E-Print Network [OSTI]

. INTRODUCTION Sporadic energy releases on the Sun can accelerate solar ener- getic particles (SEPs. The American Astronomical Society. All rights reserved. Printed in the U.S.A. OCCURRENCE OF EXTREME SOLAR-90014 Oulu, Finland; ilya.usoskin@oulu.fi 2 Ioffe Physical-Technical Institute of RAS, 194021 St

Usoskin, Ilya G.

194

Scale dependence of native and alien species richness in North American floras  

E-Print Network [OSTI]

Scale dependence of native and alien species richness in North American floras Vliv mítka studia na of native and alien species richness in North American flo- ras. ­ Preslia 78: 427­436. I analyzed data from and alien diversity vary as a function of spatial grain. Moving window multi- ple regression revealed

Minnesota, University of

195

Isotopes Environ. Health Stud., 2003, Vol. 39(1), pp. 4152 TREE SPECIES OF THE CENTRAL AMAZON AND  

E-Print Network [OSTI]

AND SOIL MOISTURE ALTER STABLE ISOTOPE COMPOSITION OF NITROGEN AND OXYGEN IN NITROUS OXIDE EVOLVED FROM SB RAS, Krasnoyarsk, Russia; b Department of Biological Sciences and Merriam-Powell Center; Oxygen 18; Tree species; Tropical soils INTRODUCTION The increase in the atmospheric concentration

Lehmann, Johannes

196

RUSSIAN ACADEMY OF SCIENCES BUDKER INSTITUTE OF NUCLEAR PHYSICS  

E-Print Network [OSTI]

RUSSIAN ACADEMY OF SCIENCES BUDKER INSTITUTE OF NUCLEAR PHYSICS SIBERIAN BRANCH Compiled by A.V. Zaytseva,b a Budker Institute of Nuclear Physics, 630090 Novosibirsk, Russia b Novosibirsk State University, 630090 Novosibirsk, Russia c Budker Institute of Nuclear Physics, SB RAS #12; Preface 5 1 General surveys

197

RUSSIAN ACADEMY OF SCIENCES BUDKER INSTITUTE OF NUCLEAR PHYSICS  

E-Print Network [OSTI]

RUSSIAN ACADEMY OF SCIENCES BUDKER INSTITUTE OF NUCLEAR PHYSICS SIBERIAN BRANCH V.S. Fadin, R of colours V.S. Fadina , R. Fioreb a Budker Institute of Nuclear Physics, and Novosibirsk State University of Nuclear Physics, SB RAS #12;. 1 Introduction In the BFKL approach [1], impact factors appear

198

College of Medicine RM Radiation Medicine  

E-Print Network [OSTI]

processes; selected nuclear reactions; basic radiation detection and dosimetry. Prereq: PHY 213 or 232; MA, and nuclear medical physics. Prereq or concur: RM/PHY 472G or consent of instructor. (Same as PHY/RAS 546.) RM 601 ADVANCED RADIATION DOSIMETRY. (2

MacAdam, Keith

199

Super-Elastic and Plastic Shock Waves Generated by Lasers N.A. Inogamov a,1  

E-Print Network [OSTI]

Super-Elastic and Plastic Shock Waves Generated by Lasers N.A. Inogamov a,1 , V.V. Zhakhovsky b,3 fortov@ihed.ras.ru, i oleynik@usf.edu Keywords: Femtosecond laser-matter interactions, elastic-plastic there is an elastic shock wave (SW), which propagates before the strong plastic shock with plastic pressures of up

Fominov, Yakov

200

C16C29 homologous series of monomethylalkanes in the pyrolysis products of a Holocene microbial mat  

E-Print Network [OSTI]

products of kerogen isolated from a Holocene microbial mat collected in Abu Dhabi (United Arab Emirates assemblage sampled from the Abu Dhabi sabkha (United Arab Emirates) are analysed for MMAs. The carbon number was collected in Abu Dhabi (United Arab Emirates) along a section of the Ras al Khaf channel (Kenig, 1991

Kenig, Fabien

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Mon. Not. R. Astron. Soc. 000, 127 (2011) Printed 7 January 2011 (MN LATEX style file v2.2) The ATLAS3D  

E-Print Network [OSTI]

.2) The ATLAS3D project ­ I. A volume-limited sample of 260 nearby early-type galaxies: science goals, PO Box 1312, D-85478 Garching, Germany 12Space Telescope European Coordinating Facility, European November 2 c 2011 RAS #12;2 M. Cappellari et al. ABSTRACT The ATLAS3D project is a multi-wavelength survey

Bureau, Martin

202

Mon. Not. R. Astron. Soc. 000, 130 (2011) Printed 18 February 2011 (MN LATEX style file v2.2) The ATLAS3D  

E-Print Network [OSTI]

.2) The ATLAS3D project ­ II. Morphologies, kinemetric features and alignment between photometric and kinematic Facility, European Southern Observatory, Karl-Schwarzschild-Str 2, 85748 Garching, Germany 9 Gemini, Socorro, NM 87801, USA 18 February 2011 c 2011 RAS #12;2 Davor Krajnovi´c et al. ABSTRACT We use the ATLAS

Bureau, Martin

203

U.S. Department of the Interior November 2013 U.S. Geological Survey  

E-Print Network [OSTI]

(t/yr) at its 270,000-t/yr Hannibal smelter. A decision by the Public Utilities Commission of Ohio/yr smelter in Ras al Khair, Saudi Arabia. Potline instability was cited as the reason for the shutdown least efficient smelters in Russia, citing high costs. The Ural, Volgograd, and Volkhov smelters were

204

RELIABILITY, AVAILABILITY, AND SERVICEABILITY FOR PETASCALE HIGH-END COMPUTING AND BEYOND  

SciTech Connect (OSTI)

Our project is a multi-institutional research effort that adopts interplay of RELIABILITY, AVAILABILITY, and SERVICEABILITY (RAS) aspects for solving resilience issues in highend scientific computing in the next generation of supercomputers. results lie in the following tracks: Failure prediction in a large scale HPC; Investigate reliability issues and mitigation techniques including in GPGPU-based HPC system; HPC resilience runtime & tools.

Chokchai "Box" Leangsuksun

2011-05-31T23:59:59.000Z

205

Proceedings of EARSeL-SIG-Workshop LIDAR, Dresden/FRG, June 16 17, 2000 EARSeL eProceedings No. 1 148  

E-Print Network [OSTI]

-06-3048-6038 ABSTRACT The development of sensing subsystems is crucial to the operation of highly autonomous robots performance laser range finder. The sensor will be installed on an autonomous rover (RAS), lodged surfaces and from the poor transparency of the atmos- phere caused by wind-driven ice microcrystals

Oldenburg, Carl von Ossietzky Universität

206

The Role of Magnesium for Geometry and Charge in GTP Hydrolysis, Revealed by Quantum Mechanics/Molecular Mechanics Simulations  

E-Print Network [OSTI]

The Role of Magnesium for Geometry and Charge in GTP Hydrolysis, Revealed by Quantum Mechanics, People's Republic of China ABSTRACT The coordination of the magnesium ion in proteins by triphosphates conversion. For example, in Ras the magnesium ion contributes to the catalysis of GTP hydrolysis

Gerwert, Klaus

207

ing delivery of shipment. For  

E-Print Network [OSTI]

of Food arid . Fluid Intake Edited by Edward M. Stricker Univmity oj Pittsburgh Pittsburgh, Pennsylvania living. The same fact, that most free-living omnivores live in r~.as in which no single food provides,-contributed to relatively independent literatures, and employed r- ferent theoretical perspectives. " In a landmark series

Galef Jr., Bennett G.

208

Matthew K. MacDonald 401 Crew Building, Kings Buildings  

E-Print Network [OSTI]

: hydrometeorology, snow hydrology, land surface modelling, micrometeorology Education: Ph.D. School of Geo-RAS, MESH Other software: R, MATLAB, ArcGIS, Loggernet Instrumentation: Campbell Scientific meteorologicalDonald MK, DeBeer CM, Brown T. 2013. Multi-variable evaluation of hydrological model predictions

209

Elevator Pitches University of Birmingham  

E-Print Network [OSTI]

, Cyber Security, Telecoms, Unified Messaging, CRM (ACT), Storage Solutions, Disaster Recovery, Document;#12;#12;Thank You! Next Pitch #12;Software Tools to Program large distributed infrastructures such as Cloud, Cloud, security What we do - 9 PhD students and RAs -Worked at HP, BT and IBM Resulted in - software

Birmingham, University of

210

Blognoon: Exploring a Topic in the Blogosphere Maria Grineva  

E-Print Network [OSTI]

Programming of RAS. Copyright is held by the International World Wide Web Conference Com- mittee (IW3C2. The technology behind Blognoon leverages Wikipedia as the world biggest resource of human knowledge that contain Clean tech concept and also relevant concepts such as Renewable energy and Biofuel. Clean tech

Tomkins, Andrew

211

Selective hydrolysis of wastewater sludge Part 1, September 2007  

E-Print Network [OSTI]

Report Selective hydrolysis of wastewater sludge Part 1, September 2007 Model calculations and cost "Selective hydrolysis of wastewater sludge" is supported by EnergiNet.DK under the PSO-F&U projects having National Laboratory, Rambøll, the Estate of Overgaard and SamRas. The wastewater treatment plant Esbjerg

212

Coupling Water and Smoke to Thin Deformable and Rigid Shells Eran Guendelman  

E-Print Network [OSTI]

boundary conditions for the fluid. Although this often used method works well for problems where the solid). Abstract We present a novel method for solid/fluid coupling that can treat infinitesimally thin solids modeled by a lower dimensional triangu- lated surface. Since classical solid/fluid coupling algorithms ras

Stanford University

213

RASRAFMEK-dependent oxidative cell death involving voltage-dependent anion channels  

E-Print Network [OSTI]

LETTERS RASRAFMEK-dependent oxidative cell death involving voltage-dependent anion channels J. Fridman1 , Adam J. Wolpaw1 , Inese Smukste1 , John M. Peltier3 , J. Jay Boniface3 , Richard Smith that discriminate between the genetic makeup of normal cells and tumour cells are valuable for treating and under

Stockwell, Brent R.

214

Overarching Hypothesis of Antarctic RIMEOverarching Hypothesis of Antarctic RIME ""The Ross Sea region is critical in the exchange ofThe Ross Sea region is critical in the exchange of  

E-Print Network [OSTI]

the complexity of these processes in the vicinity of Ross Island. The boundary layer wind, which is influenced by the RAS, is strongly modified by the topography, as is the precipitation distribution. The current generation of atmospheric models gives an incomplete depiction of the profiles of momentum and moisture near

Howat, Ian M.

215

Volume 182. number 5 CHEMICAL PHYSICSLETTERS 9August I99 I Synthesis and characterization  

E-Print Network [OSTI]

Goodman Department o/Chemistry, Te.ras A&M Universit~~,College Station, TX 77843-3255, USA Received IO May with domains that coexist wtth metallic Mg particles. The heat of sublimation of three-dimensional MgO Islands

Goodman, Wayne

216

RUSSIAN ACADEMY OF SCIENCES BUDKER INSTITUTE OF NUCLEAR PHYSICS  

E-Print Network [OSTI]

RUSSIAN ACADEMY OF SCIENCES BUDKER INSTITUTE OF NUCLEAR PHYSICS SIBERIAN BRANCH D.S. Gurov, P.V. Martyshkin, V.V. Petrov, V.V. Zuev Budker Institute of Nuclear Physics 630090, Novosibirsk, Russia M are included. @ Budker Institute of Nuclear Physics SB RAS #12

217

Atmos. Chem. Phys., 14, 69536965, 2014 www.atmos-chem-phys.net/14/6953/2014/  

E-Print Network [OSTI]

, as in the case of sand, but with opposite slopes. 1 Introduction Studies of climate change are of enormous. Tzanis1, and A. V. Vasilyev4 1Climate Research Group, Division of Environmental Physics and Meteorology RAS), Russian Academy of Sciences, St. Petersburg, Russia 3Division of Electronic Engineering

Pierce, Jeffrey

218

Long-Term Climate Change Commitment and Reversibility: An EMIC Intercomparison KIRSTEN ZICKFELD,a  

E-Print Network [OSTI]

Long-Term Climate Change Commitment and Reversibility: An EMIC Intercomparison KIRSTEN ZICKFELD. Obukhov Institute of Atmospheric Physics, RAS, Moscow, Russia f Potsdam Institute for Climate Impact of Intermediate Complexity (EMICs) undertaken in support of the Intergovernmental Panel on Climate Change (IPCC

Matsumoto, Katsumi

219

Hydrol. Earth Syst. Sci., 11, 18311841, 2007 www.hydrol-earth-syst-sci.net/11/1831/2007/  

E-Print Network [OSTI]

System Modeling, Pacific Institute of Geography, FEB RAS, Russia 2Delft University of Technology, Faculty by statistically significant changes in such monthly teleconnection indices, as the Arctic and North Pacific by Thomp- son and Wallace (1998, 2000). Another well known climate decennial-scale phenomenon, named

Paris-Sud XI, Université de

220

Recent Climate Changes in Precipitable Water in the Global Tropics as Revealed in NCEP/NCAR Reanalysis  

E-Print Network [OSTI]

1 Recent Climate Changes in Precipitable Water in the Global Tropics as Revealed in NCEP: 1 (808) 956-2877 Email: chu@hawaii.edu #12;2 Abstract For the first time, long-term climate changes/NCAR Reanalysis Igor I. Zveryaev and Pao-Shin Chu* P.P. Shirshov Institute of Oceanology, RAS, Moscow, Russia

Hawai'i at Manoa, University of

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Color-Dependent Conductance of Graphene with Adatoms J. Schelter,1  

E-Print Network [OSTI]

of Technology, 76021 Karlsruhe, Germany 3 L. D. Landau Institute for Theoretical Physics RAS, 119334 Moscow of Wu¨rzburg, 97074 Wu¨rzburg, Germany 2 Institut fu¨r Nanotechnologie, Karlsruhe Institute of 3­14 eV [3] in sharp contrast to clean graphene, which has a gapless excitation spectrum [4

Fominov, Yakov

222

Over the past several years, Lyon Arboretum staff along  

E-Print Network [OSTI]

and her students for furnishing us with Chinese, Japanese, and Korean language translations, and Ras important to her. I recorded many stories about the early stages in her de- veloping the Ethnobotanical was the first woman in her home state of Arkansas to be accepted in the Peace Corps and was sent to the Philip

223

Acute ethanol intake induces superoxide anion generation and mitogen-activated protein kinase phosphorylation in rat aorta: A role for angiotensin type 1 receptor  

SciTech Connect (OSTI)

Ethanol intake is associated with increase in blood pressure, through unknown mechanisms. We hypothesized that acute ethanol intake enhances vascular oxidative stress and induces vascular dysfunction through reninangiotensin system (RAS) activation. Ethanol (1 g/kg; p.o. gavage) effects were assessed within 30 min in male Wistar rats. The transient decrease in blood pressure induced by ethanol was not affected by the previous administration of losartan (10 mg/kg; p.o. gavage), a selective AT{sub 1} receptor antagonist. Acute ethanol intake increased plasma renin activity (PRA), angiotensin converting enzyme (ACE) activity, plasma angiotensin I (ANG I) and angiotensin II (ANG II) levels. Ethanol induced systemic and vascular oxidative stress, evidenced by increased plasma thiobarbituric acid-reacting substances (TBARS) levels, NAD(P)H oxidase?mediated vascular generation of superoxide anion and p47phox translocation (cytosol to membrane). These effects were prevented by losartan. Isolated aortas from ethanol-treated rats displayed increased p38MAPK and SAPK/JNK phosphorylation. Losartan inhibited ethanol-induced increase in the phosphorylation of these kinases. Ethanol intake decreased acetylcholine-induced relaxation and increased phenylephrine-induced contraction in endothelium-intact aortas. Ethanol significantly decreased plasma and aortic nitrate levels. These changes in vascular reactivity and in the end product of endogenous nitric oxide metabolism were not affected by losartan. Our study provides novel evidence that acute ethanol intake stimulates RAS activity and induces vascular oxidative stress and redox-signaling activation through AT{sub 1}-dependent mechanisms. These findings highlight the importance of RAS in acute ethanol-induced oxidative damage. -- Highlights: ? Acute ethanol intake stimulates RAS activity and vascular oxidative stress. ? RAS plays a role in acute ethanol-induced oxidative damage via AT{sub 1} receptor activation. ? Translocation of p47phox and MAPKs phosphorylation are downstream effectors. ? Acute ethanol consumption increases the risk for acute vascular injury.

Yogi, Alvaro; Callera, Glaucia E. [Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario (Canada)] [Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario (Canada); Mecawi, Andr S. [Department of Physiology, Faculty of Medicine of Ribeiro Preto, University of So Paulo (USP), Ribeiro Preto, SP (Brazil)] [Department of Physiology, Faculty of Medicine of Ribeiro Preto, University of So Paulo (USP), Ribeiro Preto, SP (Brazil); Batalho, Marcelo E.; Carnio, Evelin C. [Department of General and Specialized Nursing, College of Nursing of Ribeiro Preto, USP, So Paulo (Brazil)] [Department of General and Specialized Nursing, College of Nursing of Ribeiro Preto, USP, So Paulo (Brazil); Antunes-Rodrigues, Jos [Department of Physiology, Faculty of Medicine of Ribeiro Preto, University of So Paulo (USP), Ribeiro Preto, SP (Brazil)] [Department of Physiology, Faculty of Medicine of Ribeiro Preto, University of So Paulo (USP), Ribeiro Preto, SP (Brazil); Queiroz, Regina H. [Department of Clinical, Toxicological and Food Science Analysis, Faculty of Pharmaceutical Sciences, USP, So Paulo (Brazil)] [Department of Clinical, Toxicological and Food Science Analysis, Faculty of Pharmaceutical Sciences, USP, So Paulo (Brazil); Touyz, Rhian M. [Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario (Canada)] [Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario (Canada); Tirapelli, Carlos R., E-mail: crtirapelli@eerp.usp.br [Department of Psychiatric Nursing and Human Sciences, Laboratory of Pharmacology, College of Nursing of Ribeiro Preto, USP, Ribeiro Preto, SP (Brazil)

2012-11-01T23:59:59.000Z

224

Regmi Research Series ,Year 16, December 31, 1984  

E-Print Network [OSTI]

not be maje 311'd.i1able. CJ:herwise, he ordered, the duties shOJld b\\:;l coll~cted thro.lgh gorernment employees on amanat b.:l8is. siddhi Lal, a r.as1dent of Nhaikantala in K;j;.hrnatklu, then o ffEQtd . to raise th~ amount by y~ another 5 Percent. Naib... not be maje 311'd.i1able. CJ:herwise, he ordered, the duties shOJld b\\:;l coll~cted thro.lgh gorernment employees on amanat b.:l8is. siddhi Lal, a r.as1dent of Nhaikantala in K;j;.hrnatklu, then o ffEQtd . to raise th~ amount by y~ another 5 Percent. Naib...

Regmi, Mahesh C

1984-01-01T23:59:59.000Z

225

Considerations for Contractile Electroactive Materials and Actuators  

SciTech Connect (OSTI)

Ras Labs produces contractile electroactive polymer (EAP) based materials and actuators that bend, swell, ripple, and contract (new development) with low electric input. In addition, Ras Labs produces EAP materials that quickly contract and expand, repeatedly, by reversing the polarity of the electric input, which can be cycled. This phenomenon was explored using molecular modeling, followed by experimentation. Applied voltage step functions were also investigated. High voltage steps followed by low voltage steps produced a larger contraction followed by a smaller contraction. Actuator control by simply adjusting the electric input is extremely useful for biomimetic applications. Muscles are able to partially contract. If muscles could only completely contract, nobody could hold an egg, for example, without breaking it. A combination of high and low voltage step functions could produce gross motor function and fine manipulation within the same actuator unit. Plasma treated electrodes with various geometries were investigated as a means of providing for more durable actuation.

Lenore Rasmussen, David Schramm, Paul Rasmussen, Kevin Mullaly, Ras Labs, LLC, Intelligent Materials for Prosthetics & Automation, Lewis D. Meixler, Daniel Pearlman and Alice Kirk

2011-05-23T23:59:59.000Z

226

Waveguide detection of right-angle-scattered light in flow cytometry  

DOE Patents [OSTI]

A transparent flow cell is used as an index-guided optical waveguide. A detector for the flow cell but not the liquid stream detects the Right-Angle-Scattered (RAS) Light exiting from one end of the flow cell. The detector(s) could view the trapped RAS light from the flow cell either directly or through intermediate optical light guides. If the light exits one end of the flow cell, then the other end of the flow cell can be given a high-reflectivity coating to approximately double the amount of light collected. This system is more robust in its alignment than the traditional flow cytometry systems which use imaging optics, such as microscope objectives.

Mariella, Jr., Raymond P. (Danville, CA)

2000-01-01T23:59:59.000Z

227

Seismic and source characteristics of large chemical explosions. Final report  

SciTech Connect (OSTI)

From the very beginning of its arrangement in 1947, the Institute for Dynamics of the Geospheres RAS (former Special Sector of the Institute for physics of the Earth, RAS) was providing scientific observations of effects of nuclear explosions, as well as large-scale detonations of HE, on environment. This report presents principal results of instrumental observations obtained from various large-scale chemical explosions conducted in the Former-Soviet Union in the period of time from 1957 to 1989. Considering principal aim of the work, tamped and equivalent chemical explosions have been selected with total weights from several hundreds to several thousands ton. In particular, the selected explosions were aimed to study scaling law from excavation explosions, seismic effect of tamped explosions, and for dam construction for hydropower stations and soil melioration. Instrumental data on surface explosions of total weight in the same range aimed to test military technics and special objects are not included.

Adushkin, V.V.; Kostuchenko, V.N.; Pernik, L.M.; Sultanov, D.D.; Zcikanovsky, V.I.

1995-01-01T23:59:59.000Z

228

4 Science $ervj.ce Feature ? IVHY THE \\iEA'L?;IER  

E-Print Network [OSTI]

there been uncomfortable and expensive water shortage, but also frlrest fires have been un- Usually the water stored i n the Sier- ras at the end of the winter was the least i n u?ry ;YC"R'~~S. iSot only has juicy oranges have of water this tdnter ! (Tomorrav: Cold Vave Outposts) All rights reserved by Science

229

Marginal Cost of Steam and Power from Cogeneration Systems Using a Rational Value-Allocation Procedure  

E-Print Network [OSTI]

-Gwaiz, BS EE Energy Conservation Engineer Saudi Aramco, Ras Tanura, Saudi Arabia majid.gwaiz@aramco.com ABSTRACT The problem of pricing steam and power from cogeneration systems has confounded engineers, economists, and accountants for a very... MARGINAL COST OF STEAM AND POWER FROM COGENERATION SYSTEMS USING A RATIONAL VALUE-ALLOCATION PROCEDURE Jimmy D Kumana, MS ChE Energy Conservation Specialist Saudi Aramco, Dhahran, Saudi Arabia jimmy.kumana@aramco.com Majid M Al...

Kumana, J. D.; Al-Gwaiz, M. M.

2004-01-01T23:59:59.000Z

230

A&A manuscript no. (will be inserted by hand later)  

E-Print Network [OSTI]

are approximately solar above [Fe/H] ;2:2 where they decrease rapidly by 0.5 - 0.6 dex. The direct method based offprint requests to: L. Mashonkina, e-mail: ml@astro.ksu.ras.ru ? Based on observations at the German- citation energy of 0:7 eV) these Ba II lines can be detected even in extremely metal-poor stars. Two types

Gehren, Thomas

231

Notes 14. Experimental identification of bearing force coefficients  

E-Print Network [OSTI]

An example of system parameter identification (Hybrid Brush Seal) Luis San Andr?s (lecturer) Thanks to Adolfo Delgado, Jos? Baker (RAs) & support from Siemens Power Generation MEEN 617 - April 2008 Structural parameters K shaft = 243 lbf/in (42...Notes 14. IDENTIFICATION OF BEARING FORCE COEFFICIENTS. ? Dr. Luis San Andr?s (2009) 1 Handout # 14 (MEEN 626) Application example Experimental identification of bearing force coefficients Experimental identification of the dynamic force...

San Andres, Luis

2009-01-01T23:59:59.000Z

232

Percutaneous Embolization of Transhepatic Tracks for Biliary Intervention  

SciTech Connect (OSTI)

Significant pain can occur after removing transhepatic catheters from biliary access tracks, after percutaneous biliary drainage (PBD) or stenting. We undertook a randomized prospective study to ascertain whether track embolization decreases the amount of pain or analgesic requirement after PBD. Fifty consecutive patients (M:F, 22:28; age range:29-85 years; mean age: 66.3 years) undergoing PBD were randomized to receive track embolization or no track embolization after removal of biliary drainage catheters. A combination of Lipoidol and n-butyl cyanoacrylate were used to embolize transhepatic tracks using an 8F dilator. The patients who did not have track embolization performed had biliary drainage catheters removed over a guide wire. A visual analog scoring (VAS) system was used to grade pain associated with catheter removal, 24 h afterward. A required analgesic score (RAS) was devised to tabulate the analgesia required. No analgesia had a score of 0, oral or rectal nonopiate analgesics had a score of 1, oral opiates had a score of 2, and parenteral opiates had a score of 3. The average VAS and RAS for both groups were calculated and compared.Seven patients were excluded for various reasons, leaving 43 patients in the study group. Twenty-one patients comprised the embolization group and 22 patients comprised the nonembolization group. The mean biliary catheter dwell time was not significantly different (p > 0.05) between the embolization group and nonembolization (mean: 5.4 days vs 6.9 days, respectively). In the nonembolization group, the mean VAS was 3.4. Eight patients required parenteral opiates, three patients required oral opiates, and five patients required oral or rectal analgesics, yielding a mean RAS of 1.6. In the embolization group, the mean VAS was 0.9. No patient required parenteral opiates, six patients required oral opiates, and two patients had oral analgesia. The average RAS was 0.6. Both the VAS and the RAS were significantly lower in the embolization group compared with the nonembolization group (p < 0.0023 and p < 0.002, respectively). No complications were seen related to track embolization. Percutaneous track embolization after removal of biliary drainage catheters decreases patient's perception of pain and decreases the amount of required analgesia. In particular, the amount of opiate analgesia required is considerably less.

Lyon, Stuart M.; Terhaar, Olaf; Given, Mark F.; O'Dwyer, Helena M.; McGrath, Frank P.; Lee, Michael J. [Beaumont Hospital, Department of Academic Radiology (Ireland)], E-mail: mlee@rcsi.ie

2006-12-15T23:59:59.000Z

233

No-arbitrage of second kind in countable markets with proportional transaction costs  

E-Print Network [OSTI]

Motivated by applications to bond markets, we propose a multivariate framework for discrete time financial markets with proportional transaction costs and a countable infinite number of tradable assets. We show that the no-arbitrage of second kind property (NA2 in short), introduced by \\cite{ras09} for finite dimensional markets, allows to provide a closure property for the set of attainable claims in a very natural way, under a suitable efficient friction condition. We also extend to this context the equivalence between NA2 and the existence of multiple (strictly) consistent price systems.

Bouchard, Bruno

2010-01-01T23:59:59.000Z

234

"Skinny Milky Way please", says Sagittarius  

E-Print Network [OSTI]

that we do not tie the circular speed at the Solar radius to the fitted halo model as this induces a bias at small Galactocentric radii of the order of 10%. c 2014 RAS, MNRAS 000, 116 Skinny Milky Way, says Sagittarius. 3 Figure 1. The formation of a... tidal stream in the energy and angular momentum space. Each of the three panels show snapshots of an N-body simulation in E and L space at different time steps along the progenitors orbit, namely at pericentre (left), between pericentre and apocentre...

Gibbons, S. L. J.; Belokurov, V.; Evans, N. W.

2014-01-01T23:59:59.000Z

235

Analysis on the energy efficiency of variable-frequency air conditioners (Hitachi models as an example) Jim Jr-Min Lin 2014.09.26  

E-Print Network [OSTI]

Analysis on the energy efficiency of variable-frequency air conditioners (Hitachi models (Max) Energy Efficiency @min load Energy Efficiency @Max load kW kW kW kW W/W W/W RAS-22NB 1.00 3.20 0 Efficiency @min load Energy Efficiency @Max load kW kW kW kW W/W W/W RAM-5FNS(B) - 12.5 - 2.91 - 4.3 RAM-6FNS

236

Compositions and methods for detecting Noonan syndrome  

DOE Patents [OSTI]

Diagnostic and therapeutic applications for Noonan Syndrome are described. The diagnostic and therapeutic applications are based on certain mutations in a RAS-specific guanine nucleotide exchange factor gene SOS1 or its expression product. The diagnostic and therapeutic applications are also based on certain mutations in a serine/threonine protein kinase gene RAF1 or its expression product thereof. Also described are nucleotide sequences, amino acid sequences, probes, and primers related to RAF1 or SOS1, and variants thereof, as well as host cells expressing such variants.

Gelb, Bruce D. (New York, NY); Tartaglia, Marco (Rome, IT); Pennacchio, Len (Walnut Creek, CA)

2012-07-17T23:59:59.000Z

237

The El Salvadoran refugee move to Belize: a geographic study of refugee migration  

E-Print Network [OSTI]

information on the individual refugee not alluded to in the schedule-based survey, was available through the United States Agency for International Development (USAID). Their study, entitled El Salvad r: A ricul- tural ect r Asses en 1 77 (1977), provides... use and ownership of the land by the majority rural poor are central to the future political and economic life of El Salvador. Thomas R Anderson's T e W r of he Di e Hond ras nd E~ll 968 (l981) * i I gi 1 dit' *' I ' Fl S I 4 that resulted...

McElroy, Charles Scott

1986-01-01T23:59:59.000Z

238

Merging as a key to reforming of disk and AGN triggering in Sy galaxy Mrk334  

E-Print Network [OSTI]

We have studied the kinematics of the ionized gas and stellar component in Mrk334 using methods of panoramic (3D) spectroscopy. The observations were performed at the prime focus of the SAO RAS 6-m telescope with the integral-field spectrograph MPFS (Afanasiev et al. 2001) and with a scanning Fabry-Perot interferometer (FPI), installed on the multimode device SCORPIO (Afanasiev & Moiseev 2005). Based on these data, the monochromatic maps and velocity fields in different emission lines of the ionized gas were constructed. The diagnostic diagrams have been made based on the emission lines ratios.

A. A. Smirnova; A. V. Moiseev

2008-01-10T23:59:59.000Z

239

Furrow Diking and Subsoiling Studies in the Rolling Plains.  

E-Print Network [OSTI]

TDOC Z TA245.7 9873 NO.1585 8-1585 ~ ...-------------. Furrow Diking and Subsoiling Studies in the Rolling Plains -LIBR~R I JAN?198s r~as ~&4I . _____ __ -'U'J"!!II~.s: THE TEXAS AGRICULTURAL EXPERIMENT STATION/Neville P. Clarke... 1195a 900a 1602a 1556a 1847a 1481a 1778a 1585a 1936a 1327 1672 1984 Ibs/A 2266a 2056a 2500a 2323a 2649a 2568a 2682a 2408a 2675a 2380a 2554 2347 1985 Ibs/A 3342 3202 3344 3578 2934 3079 3555 3646 3147 3638 3264 3429 Average 1036a...

Gerard, C.J.

1987-01-01T23:59:59.000Z

240

Annotated bibliography of coal in the Caribbean region. [Lignite  

SciTech Connect (OSTI)

The purpose of preparing this annotated bibliography was to compile information on coal localities for the Caribbean region used for preparation of a coal map of the region. Also, it serves as a brief reference list of publications for future coal studies in the Caribbean region. It is in no way an exhaustive study or complete listing of coal literature for the Caribbean. All the material was gathered from published literature with the exception of information from Cuba which was supplied from a study by Gordon Wood of the US Geological Survey, Branch of Coal Resources. Following the classification system of the US Geological Survey (Wood and others, 1983), the term coal resources has been used in this report for reference to general estimates of coal quantities even though authors of the material being annotated may have used the term coal reserves in a similar denotation. The literature ranges from 1857 to 1981. The countries listed include Colombia, Mexico, Venezuela, Cuba, the Dominican Republic, Haiti, Jamaica, Puerto Rico, and the countries of Central America.

Orndorff, R.C.

1985-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

TBC-Domain GAPs for Rab GTPases Accelerate GTP Hydrolysis by a Dual-Finger Mechanism  

SciTech Connect (OSTI)

Rab GTPases regulate membrane trafficking by cycling between inactive (GDP-bound) and active (GTP-bound) conformations. The duration of the active state is limited by GTPase-activating proteins (GAPs), which accelerate the slow intrinsic rate of GTP hydrolysis. Proteins containing TBC (Tre-2, Bub2 and Cdc16) domains are broadly conserved in eukaryotic organisms and function as GAPs for Rab GTPases as well as GTPases that control cytokinesis. An exposed arginine residue is a critical determinant of GAP activity in vitro and in vivo. It has been expected that the catalytic mechanism of TBC domains would parallel that of Ras and Rho family GAPs. Here we report crystallographic, mutational and functional analyses of complexes between Rab GTPases and the TBC domain of Gyp1p. In the crystal structure of a TBC-domain-Rab-GTPase-aluminium fluoride complex, which approximates the transition-state intermediate for GTP hydrolysis, the TBC domain supplies two catalytic residues in trans, an arginine finger analogous to Ras/Rho family GAPs and a glutamine finger that substitutes for the glutamine in the DxxGQ motif of the GTPase. The glutamine from the Rab GTPase does not stabilize the transition state as expected but instead interacts with the TBC domain. Strong conservation of both catalytic fingers indicates that most TBC-domain GAPs may accelerate GTP hydrolysis by a similar dual-finger mechanism.

Pan,X.; Eathiraj, S.; Lambright, D.

2006-01-01T23:59:59.000Z

242

Calcination/dissolution chemistry development Fiscal year 1995  

SciTech Connect (OSTI)

The task {open_quotes}IPC Liaison and Chemistry of Thermal Reconstitution{close_quotes} is a $300,000 program that was conducted in Fiscal Year (FY) 1995 with U.S. Department of Energy (DOE) Office of Research and Development (EM-53) Efficient Separations and Processing Crosscutting Program supported under technical task plan (TTP) RL4-3-20-04. The principal investigator was Cal Delegard of the Westinghouse Hanford Company (WHC). The task encompassed the following two subtasks related to the chemistry of alkaline Hanford Site tank waste: (1) Technical Liaison with the Institute of Physical Chemistry of the Russian Academy of Science (IPC/RAS) and its research into the chemistry of transuranic elements (TRU) and technetium (Tc) in alkaline media. (2) Laboratory investigation of the chemistry of calcination/dissolution (C/D) (or thermal reconstitution) as an alternative to the present reference Hanford Site tank waste pretreatment flowsheet, Enhanced Sludge Washing (ESW). This report fulfills the milestone for the C/D subtask to {open_quotes}Provide End-of-Year Report on C/D Laboratory Test Results{close_quotes} due 30 September 1995. A companion report, fulfilling the milestone to provide an end-of-year report on the IPC/RAS liaison, also has been prepared.

Delegard, C.H.

1995-09-01T23:59:59.000Z

243

Remedial action plan and site design for stabilization of the inactive uranium processing site at Naturita, Colorado. Remedial Action Selection Report, Appendix B of Attachment 2: Geology report, Final  

SciTech Connect (OSTI)

The uranium processing site near Naturita, Colorado, is one of 24 inactive uranium mill sites designated to be cleaned up by the US Department of Energy (DOE) under the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA), 42 USC {section} 7901 et seq. Part of the UMTRCA requires that the US Nuclear Regulatory Commission (NRC) concur with the DOE`s remedial action plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the US Environmental Protection Agency (EPA). Included in the RAP is this Remedial Action Selection Report (RAS), which describes the proposed remedial action for the Naturita site. An extensive amount of data and supporting information has been generated and evaluated for this remedial action. These data and supporting information are not incorporated into this single document but are included or referenced in the supporting documents. The RAP consists of this RAS and four supporting documents or attachments. This Attachment 2, Geology Report describes the details of geologic, geomorphic, and seismic conditions at the Dry Flats disposal site.

Not Available

1994-03-01T23:59:59.000Z

244

Activation of the MAP Kinase Cascade by Exogenous Calcium-Sensing Receptor  

SciTech Connect (OSTI)

In Rat-1 fibroblasts and ovarian surface epithelial cells, extracellular calcium induces a proliferative response which appears to be mediated by the G-protein coupled Calcium-sensing Receptor (CaR), as expression of the non-functional CaR-R795W mutant inhibits both thymidine incorporation and activation of the extracellular-regulated kinase (ERK) in response to calcium. In this report we utilized CaR-transfected HEK293 cells to demonstrate that functional CaR is necessary and sufficient for calcium-induced ERK activation. CaR-dependent ERK activation was blocked by co-expression of the Ras dominant-negative mutant, Ras N17, and by exposure to the phosphatidyl inositol 3' kinase inhibitors wortmannin and LY294002. In contrast to Rat-1 fibroblasts, CaR-mediated in vitro kinase activity of ERK2 was unaffected by tyrosine kinase inhibitor herbimycin in CaR-transfected HEK293 cells. These results suggest that usage of distinct pathways downstream of the CaR varies in a cell-type specific manner, suggesting a potential mechanism by which activation of the CaR could couple to distinct calcium-dependent responses.

Hobson, Susan A.; Wright, Jay W.; Lee, Fred; Mcneil, Scott; Bilderback, Tim R.; Rodland, Karin D.

2003-02-01T23:59:59.000Z

245

Soil Management Plan for the Oak Ridge Y-12 National Security Complex Oak Ridge, Tennessee  

SciTech Connect (OSTI)

This Soil Management Plan applies to all activities conducted under the auspices of the National Nuclear Security Administration (NNSA) Oak Ridge Y-12 National Security Complex (Y-12) that involve soil disturbance and potential management of waste soil. The plan was prepared under the direction of the Y-12 Environmental Compliance Department of the Environment, Safety, and Health Division. Soil disturbances related to maintenance activities, utility and building construction projects, or demolition projects fall within the purview of the plan. This Soil Management Plan represents an integrated, visually oriented, planning and information resource tool for decision making involving excavation or disturbance of soil at Y-12. This Soil Management Plan addresses three primary elements. (1) Regulatory and programmatic requirements for management of soil based on the location of a soil disturbance project and/or the regulatory classification of any contaminants that may be present (Chap. 2). Five general regulatory or programmatic classifications of soil are recognized to be potentially present at Y-12; soil may fall under one or more these classifications: (a) Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) pursuant to the Oak Ridge Reservation (ORR) Federal Facilities Agreement; (b) Resource Conservation and Recovery Act (RCRA); (c) RCRA 3004(u) solid waste managements units pursuant to the RCRA Hazardous and Solid Waste Amendments Act of 1984 permit for the ORR; (d) Toxic Substances and Control Act-regulated soil containing polychlorinated biphenyls; and (e) Radiologically contaminated soil regulated under the Atomic Energy Act review process. (2) Information for project planners on current and future planned remedial actions (RAs), as prescribed by CERCLA decision documents (including the scope of the actions and remedial goals), land use controls implemented to support or maintain RAs, RCRA post-closure regulatory requirements for former waste management units, legacy contamination source areas and distribution of contamination in soils, and environmental infrastructure (e.g., caps, monitoring systems, etc.) that is in place or planned in association with RAs. (3) Regulatory considerations and processes for management and disposition of waste soil upon generation, including regulatory drivers, best management practices (BMPs), waste determination protocols, waste acceptance criteria, and existing waste management procedures and BMPs for Y-12. This Soil Management Plan provides information to project planners to better coordinate their activities with other organizations and programs with a vested interest in soil disturbance activities at Y-12. The information allows project managers and maintenance personnel to evaluate and anticipate potential contaminant levels that may be present at a proposed soil disturbance site prior to commencement of activities and allows a more accurate assessment of potential waste management requirements.

None

2005-03-02T23:59:59.000Z

246

Ran GTPase protein promotes human pancreatic cancer proliferation by deregulating the expression of Survivin and cell cycle proteins  

SciTech Connect (OSTI)

Highlights: Overexpression of Ran in pancreatic cancer was correlated with histological grade. Downregulation of Ran could induce cell apoptosis and inhibit cell proliferation. The effects were mediated by cell cycle proteins, Survivin and cleaved Caspase-3. -- Abstract: Ran, a member of the Ras GTPase family, has important roles in nucleocytoplasmic transport. Herein, we detected Ran expression in pancreatic cancer and explored its potential role on tumour progression. Overexpressed Ran in pancreatic cancer tissues was found highly correlated with the histological grade. Downregulation of Ran led to significant suppression of cell proliferation, cell cycle arrest at the G1/S phase and induction of apoptosis. In vivo studies also validated that result. Further studies revealed that those effects were at least partly mediated by the downregulation of Cyclin A, Cyclin D1, Cyclin E, CDK2, CDK4, phospho-Rb and Survivin proteins and up regulation of cleaved Caspase-3.

Deng, Lin [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China) [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China); Department of Oncology, Tangdu Hospital, Fourth Military Medical University, Xian, Shaanxi 710038 (China); Lu, Yuanyuan; Zhao, Xiaodi; Sun, Yi; Shi, Yongquan; Fan, Hongwei; Liu, Changhao; Zhou, Jinfeng; Nie, Yongzhan; Wu, Kaichun [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China)] [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China); Fan, Daiming, E-mail: daimingfan@fmmu.edu.cn [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China)] [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China); Guo, Xuegang, E-mail: xuegangguo@126.com [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China)] [State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, Shaanxi 710032 (China)

2013-10-18T23:59:59.000Z

247

Net energy for production of feed mixtures containing various levels of cottonseed hulls and coastal bermudagrass hay  

E-Print Network [OSTI]

!'er 16&]966) I3zeT(s'1! 2d I' f. lect r I !, cve1 o Cotto'i. ee ' Hu]! I r v!1s on Dai ly Yr'crl In I ai:u (d!i . 13 t o 0c tone 10 & 19r&6) Br. e&r le, Te;ras ?5 fir:eac ariel Cl aclraLic Ile irr . sion for id!e Ef tc;!ts of travel of li &ur&hage re...!ci sc o&1s 'or tji. 6 f -;!! s of (oas! r!I Be& ai!d; . ass Bay I rvel or! Inc. gy 6 . i! Cos Treat&!, ent Gi oiips (du e 13 ? Ceto! er . ' 6. 1966 ? Ber v' i Le) . B5 IC! I&i!se!r e&nr! Clued&cetic Renre. , sions fo" tlie Eff acts of Cot& t...

Mark, William Howard

2012-06-07T23:59:59.000Z

248

Fiscal Year 2007 Phased Construction Completion Report for the Zone 2 Soils, Slabs, and Subsurface Structures at East Tennessee Technology Park, Oak Ridge, Tennessee  

SciTech Connect (OSTI)

The purpose of this Phased Construction Completion Report (PCCR) is to present the fiscal year (FY) 2007 results of characterization activities and recommended remedial actions (RAs) for 11 exposure units (EUs) in Zone 2 (Z2-01, Z2-03, Z2-08, Z2-23, Z2-24, Z2-28, Z2-34, Z2-37, Z2-41, Z2-43, and Z2-44) at the East Tennessee Technology Park (ETTP), which is located in the northwest corner of the U.S. Department of Energy (DOE) Oak Ridge Reservation in Oak Ridge, Tennessee (Fig. 1). ETTP encompasses a total land area of approximately 5000 acres that has been subdivided into three zones--Zone 1 ({approx}1400 acres), Zone 2 ({approx}800 acres), and the Boundary Area ({approx}2800 acres). Zone 2, which encompasses the highly industrialized portion of ETTP shown in Fig. 1, consists of all formerly secured areas of the facility, including the large processing buildings and direct support facilities; experimental laboratories and chemical and materials handling facilities; materials storage and waste disposal facilities; secure document records libraries; and shipping and receiving warehouses. The Zone 2 Record of Decision for Soil, Buried Waste, and Subsurface Structure Actions in Zone 2, East Tennessee Technology Park, Oak Ridge, Tennessee (DOE 2005) (Zone 2 ROD) specifies the future end use for Zone 2 acreage as uncontrolled industrial for the upper 10 ft of soils. Characterization activities in these areas were conducted in compliance with the Zone 2 ROD and the Dynamic Verification Strategy (DVS) and data quality objectives (DQOs) presented in the Remedial Design Report/Remedial Action Work Plan for Zone 2 Soils, Slabs, and Subsurface Structures, East Tennessee Technology Park, Oak Ridge, Tennessee (DOE 2007) (Zone 2 RDR/RAWP). The purpose of this PCCR is to address the following: (1) Document DVS characterization results for the accessible EUs in FY 2007; (2) Describe and document the risk evaluation for each EU, and determine if the EU met the Zone 2 ROD requirements for unrestricted industrial use to 10 ft bgs; (3) Identify additional areas not defined in the Zone 2 ROD that require remediation based on the DVS evaluation results; and (4) Describe the RAs performed in Zone 2. The Zone 2 ROD divided the Zone 2 area into 7 geographic areas and 44 EUs. To facilitate the DQOs of the DVS process, the Zone 2 RDR/RAWP regrouped the 44 EUs into 12 DQO scoping EU groups. These groups facilitated the DQO process by placing similar facilities and their support facilities together and allowed identification of data gaps. The EU groups were no longer pertinent after DQO planning was completed, and characterization was conducted as areas became accessible. As the opportunity to complete characterization became available, the planned DVS program was executed and completed in FY 2007 for the 11 EUs addressed in this document. The main body of this report describes both the DVS process and scope of work performed and the RAs completed. The scope and approach for performing DVS activities performed in FY 2007 that lead to action/no further action decisions are presented in Sects. 2 through 4. RAs performed in FY 2007 are presented in Sects. 5 through 10. Future land use is described in Sect. 11, and the status of all Zone 2 EUs as of this PCCR is presented in Sect. 12.

RSI

2008-03-01T23:59:59.000Z

249

A novel histone deacetylase inhibitor Chidamide induces apoptosis of human colon cancer cells  

SciTech Connect (OSTI)

Many studies have demonstrated that histone deacetylase (HDAC) inhibitors induce various tumor cells to undergo apoptosis, and such inhibitors have been used in different clinical trials against different human cancers. In this study, we designed and synthesized a novel HDAC inhibitor, Chidamide. We showed that Chidamide was able to increase the acetylation levels of histone H3 and to inhibit the PI3K/Akt and MAPK/Ras signaling pathways, which resulted in arresting colon cancer cells at the G1 phase of the cell cycle and promoting apoptosis. As a result, the proliferation of colon cancer cells was suppressed in vitro. Our data support the potential application of Chidamide as an anticancer agent in treating colon cancer. Future studies are needed to demonstrate its in vivo efficacy.

Liu, Lin [Department of Oncology, Zhong-Da Hospital of Southeast University, Nanjing 210009, Jiangsu (China)] [Department of Oncology, Zhong-Da Hospital of Southeast University, Nanjing 210009, Jiangsu (China); Chen, Baoan, E-mail: wenyu811@126.com [Department of Oncology, Zhong-Da Hospital of Southeast University, Nanjing 210009, Jiangsu (China)] [Department of Oncology, Zhong-Da Hospital of Southeast University, Nanjing 210009, Jiangsu (China); Qin, Shukui [Chinese PLA Cancer Center, The 81st PLA Hospital, Nanjing 210002, Jiangsu (China)] [Chinese PLA Cancer Center, The 81st PLA Hospital, Nanjing 210002, Jiangsu (China); Li, Suyi; He, Xiangming [Department of Oncology, Zhong-Da Hospital of Southeast University, Nanjing 210009, Jiangsu (China)] [Department of Oncology, Zhong-Da Hospital of Southeast University, Nanjing 210009, Jiangsu (China); Qiu, Shaomin; Zhao, Wei; Zhao, Hong [Department of Internal Medicine, Nanjing Municipal Cancer Hospital, Nanjing 210003, Jiangsu (China)] [Department of Internal Medicine, Nanjing Municipal Cancer Hospital, Nanjing 210003, Jiangsu (China)

2010-02-05T23:59:59.000Z

250

Land use and macroclimate in Presidio County, Texas  

E-Print Network [OSTI]

in 'igg0 "rom cire 13ex, r District arid; =-. formally or ger:ised. In 1875. 'I'hc?o(ee is derived !rem P -esidio dc-. . l N rte, as it r!as c;el I ed 'cy the Spani=h cxplorers, meaning gateuey on. Rio Craiide. 'I'hc county is loc:i, i. cl in the Trar... completion o. two major higtways. Cne of these routes, FN 170 or El Carnino del Rio, nas been completed. from Presidio to the Big Bend National Park. Money has beer acorcpriated to complete thi- road to El Paso, thereby pzoviding a. I'ighway from t'?e west...

Ellermeier, Duane Carl

1970-01-01T23:59:59.000Z

251

Cost of Cotton Production and Profit Per Acre.  

E-Print Network [OSTI]

'lie seconcl (So. 2) showing results of Jlr. Clarlr'a c~iterprising son Homer, on another piece of land, without ulanurc, :111cl with ordinary "short staple" cotton in 3 1-2 foot ram : STATE~IEXT So. 1. iF7. A. Clnrl:, Temple, Beil Co., Te.ras, lS92. OSE.... and sometime;: after plowingaroundclose uptocot,ton with do;l,le phorel ~tnck; with two 12 inch buzzard win2 sWe:ps att,achecl. Chop twice, averaging four ac:di p2r d.sy; cojt" cents p-r ax? ea:h time, total SOc. "Plow two or th~,ee times, owing t:, season...

Curtis, Geo. W.; Carson, J. W.

1893-01-01T23:59:59.000Z

252

An investigation of the applicability of the photo-electric cell to the determination of solubility  

E-Print Network [OSTI]

, sad silver chromato solutioas on ths intensity of light. Those 4sts sre represented bp ourvos in Charts II XVc VIy VIXI ~ YARIATIOE OF INTENSITY OF LIGHT WITS TIME FOR VARIOUS CONCl9lTRATIOMS OF SILVER CRLORmE 1. 00 x 10 aols A801 yor Kiter lo80... of RasGrOa mole 9or liter iisf lost isa soalo sivisisas Coassatrat ioa of Na, Cr0, mole psr liter Dsf loot ioa seals divisioas 0. 5 x 10"6 Qed X 10 O Oe9 x 10 0, 8 x10 Oe9x106 leOz105 l. lx106 12xlQ 1. 8 x 10-6 le4 x 10 led z 10 led x...

Nordsieck, Herbert Henry

1936-01-01T23:59:59.000Z

253

Positive Feedback Regulation Results in Spatial Clustering and Fast Spreading of Active Signaling Molecules on a Cell Membrane  

E-Print Network [OSTI]

Positive feedback regulation is ubiquitous in cell signaling networks, often leading to binary outcomes in response to graded stimuli. However, the role of such feedbacks in clustering, and in spatial spreading of activated molecules, has come to be appreciated only recently. We focus on the latter, using a simple model developed in the context of Ras activation with competing negative and positive feedback mechanisms. We find that positive feedback, in the presence of slow diffusion, results in clustering of activated molecules on the plasma membrane, and rapid spatial spreading as the front of the cluster propagates with a constant velocity (dependent on the feedback strength). The advancing fronts of the clusters of the activated species are rough, with scaling consistent with the Kardar-Parisi-Zhang (KPZ) equation in one dimension. Our minimal model is general enough to describe signal transduction in a wide variety of biological networks where activity in the membrane-proximal region is subject to feedback regulation.

Jayajit Das; Mehran Kardar; Arup K. Chakraborty

2009-06-29T23:59:59.000Z

254

Large Scale Structures a Gradient Lines: the case of the Trkal Flow  

E-Print Network [OSTI]

A specific asymptotic expansion at large Reynolds numbers (R)for the long wavelength perturbation of a non stationary anisotropic helical solution of the force less Navier-Stokes equations (Trkal solutions) is effectively constructed of the Beltrami type terms through multi scaling analysis. The asymptotic procedure is proved to be valid for one specific value of the scaling parameter,namely for the square root of the Reynolds number (R).As a result large scale structures arise as gradient lines of the energy determined by the initial conditions for two anisotropic Beltrami flows of the same helicity.The same intitial conditions determine the boundaries of the vortex-velocity tubes, containing both streamlines and vortex lines

Libin, Alexander S

2010-01-01T23:59:59.000Z

255

Large Scale Structures a Gradient Lines: the case of the Trkal Flow  

E-Print Network [OSTI]

A specific asymptotic expansion at large Reynolds numbers (R)for the long wavelength perturbation of a non stationary anisotropic helical solution of the force less Navier-Stokes equations (Trkal solutions) is effectively constructed of the Beltrami type terms through multi scaling analysis. The asymptotic procedure is proved to be valid for one specific value of the scaling parameter,namely for the square root of the Reynolds number (R).As a result large scale structures arise as gradient lines of the energy determined by the initial conditions for two anisotropic Beltrami flows of the same helicity.The same intitial conditions determine the boundaries of the vortex-velocity tubes, containing both streamlines and vortex lines

Alexander S. Libin

2010-07-13T23:59:59.000Z

256

Nested methylation-specific polymerase chain reaction cancer detection method  

DOE Patents [OSTI]

A molecular marker-based method for monitoring and detecting cancer in humans. Aberrant methylation of gene promoters is a marker for cancer risk in humans. A two-stage, or "nested" polymerase chain reaction method is disclosed for detecting methylated DNA sequences at sufficiently high levels of sensitivity to permit cancer screening in biological fluid samples, such as sputum, obtained non-invasively. The method is for detecting the aberrant methylation of the p16 gene, O 6-methylguanine-DNA methyltransferase gene, Death-associated protein kinase gene, RAS-associated family 1 gene, or other gene promoters. The method offers a potentially powerful approach to population-based screening for the detection of lung and other cancers.

Belinsky, Steven A. (Albuquerque, NM); Palmisano, William A. (Edgewood, NM)

2007-05-08T23:59:59.000Z

257

General and Versatile Autoinhibition of PLC Isozymes  

SciTech Connect (OSTI)

Phospholipase C (PLC) isozymes are directly activated by heterotrimeric G proteins and Ras-like GTPases to hydrolyze phosphatidylinositol 4,5-bisphosphate into the second messengers diacylglycerol and inositol 1,4,5-trisphosphate. Although PLCs play central roles in myriad signaling cascades, the molecular details of their activation remain poorly understood. As described here, the crystal structure of PLC-{beta}2 illustrates occlusion of the active site by a loop separating the two halves of the catalytic TIM barrel. Removal of this insertion constitutively activates PLC-{beta}2 without ablating its capacity to be further stimulated by classical G protein modulators. Similar regulation occurs in other PLC members, and a general mechanism of interfacial activation at membranes is presented that provides a unifying framework for PLC activation by diverse stimuli.

Hicks, Stephanie N.; Jezyk, Mark R.; Gershburg, Svetlana; Seifert, Jason P.; Harden, T. Kendall; Sondek, John (UNC)

2008-10-31T23:59:59.000Z

258

Computational chemistry in Argonne`s Reactor Analysis Division  

SciTech Connect (OSTI)

Roughly 3 years ago work on Argonne`s Integral Fast Reactor ({open_quotes}IFR{close_quotes}) was terminated and at that time, ANL funding was redirected to a number of alternative programs. One such alternative was waste management and, since disposal of spent fuel from ANL`s EBR-II reactor presents some special problems, this seemed an appropriate area for ANL work. Methods for the treatment and disposal of spent fuel (particularly from EBR-II but also from other sources) are now under very active investigation at ANL. The very large waste form development program is mainly experimental at this point, but within the Reactor Analysis ({open_quotes}RA{close_quotes}) Division a small computational chemistry program is underway, designed to supplement the experimental program. One of the most popular proposals for the treatment of much of our high-level wastes is vitrification. As noted below, this approach has serious drawbacks for EBR-II spent fuel. ANL has proposed, instead, that spent fuel first be pretreated by a special metallurgical process which produces, as waste, chloride salts of the various fission products; these salts would then be adsorbed in zeolite A, which is subsequently bonded with glass to produce a waste form suitable for disposal. So far it has been the main mission of RA`s computational chemistry program to study the process by which leaching occurs when the glass-bonded zeolite waste form is exposed to water. It is the purpose of this paper to describe RA`s computational chemistry program, to discuss the computational techniques involved in such a program, and in general to familiarize the M. and C. Division with a computational area which is probably unfamiliar to most of its member. 11 refs., 2 figs.

Gelbard, E.; Agrawal, R.; Fanning, T.

1997-08-01T23:59:59.000Z

259

Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: Possible involvement of angiotensin-converting enzyme-2  

SciTech Connect (OSTI)

Chronic cigarette smoking induces pulmonary arterial hypertension (PAH) by largely unknown mechanisms. Renin-angiotensin system (RAS) is known to function in the development of PAH. Losartan, a specific angiotensin II receptor antagonist, is a well-known antihypertensive drug with a potential role in regulating angiotensin-converting enzyme-2 (ACE2), a recently found regulator of RAS. To determine the effect of losartan on smoke-induced PAH and its possible mechanism, rats were daily exposed to cigarette smoke for 6 months in the absence and in the presence of losartan. Elevated right ventricular systolic pressure (RVSP), thickened wall of pulmonary arteries with apparent medial hypertrophy along with increased angiotensin II (Ang II) and decreased ACE2 levels were observed in smoke-exposed-only rats. Losartan administration ameliorated pulmonary vascular remodeling, inhibited the smoke-induced RVSP and Ang II elevation and partially reversed the ACE2 decrease in rat lungs. In cultured primary pulmonary artery smooth muscle cells (PASMCs) from 3- and 6-month smoke-exposed rats, ACE2 levels were significantly lower than in those from the control rats. Moreover, PASMCs from 6-month exposed rats proliferated more rapidly than those from 3-month exposed or control rats, and cells grew even more rapidly in the presence of DX600, an ACE2 inhibitor. Consistent with the in vivo study, in vitro losartan pretreatment also inhibited cigarette smoke extract (CSE)-induced cell proliferation and ACE2 reduction in rat PASMCs. The results suggest that losartan may be therapeutically useful in the chronic smoking-induced pulmonary vascular remodeling and PAH and ACE2 may be involved as part of its mechanism. Our study might provide insight into the development of new therapeutic interventions for PAH smokers.

Han Suxia; He Guangming; Wang Tao; Chen Lei; Ning Yunye; Luo Feng; An Jin; Yang Ting; Dong Jiajia; Liao Zenglin; Xu Dan [Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, and Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041 (China); Wen Fuqiang, E-mail: wenfuqiang.scu@gmail.co [Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, and Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041 (China)

2010-05-15T23:59:59.000Z

260

Report on the research conducted under the funding of the Sloan foundation postdoctoral fellowship in Computational Molecular Biology [Systematic study of protein-protein complexes] Final report  

SciTech Connect (OSTI)

A central question in molecular biology is what structural features are common at protein-protein interfaces and what energetic factors define the affinity and specificity of protein-protein association. Analysis of structural and mutational data on protein-protein interfaces revealed that protein-protein interfaces of different functional classes contain many more energetically important charged and polar residues than was previously thought. Since, in the context of protein folding studies, polar interactions are believed to destabilize the folded proteins, this observation raised the question as to the forces that determine the stability of protein complexes. To investigate this issue in detail, the authors developed a number of partitioning schemes that allowed them to investigate the role of selected residues, ion pairs, and networks of polar interactions in protein-protein association. The methods developed were applied to the analysis of four different protein-protein interfaces: the ribonuclease barnase and its inhibitor barstar, the human growth hormone and its receptor, subtype N9 influenze virus neuraminidase and NC41 antibody, and the Ras Binding Domain of kinase cRaf and a Ras homologue Rap1A. The calculations revealed a surprising variability in how polar interactions affect the stability of different complexes. The finding that positions of charged and polar residues on protein-protein interfaces are optimized with respect to electrostatic interactions suggests that this property can be employed for the discrimination between native conformations and trial complexes generated by a docking algorithm. Analysis indicated the presence of SH2 domains in Janus family of non-receptor protein tyrosine kinases.

Sheinerman, Felix

2001-06-01T23:59:59.000Z

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261

Chronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells  

SciTech Connect (OSTI)

Cadmium is a known human lung carcinogen. Here, we attempt to develop an in vitro model of cadmium-induced human lung carcinogenesis by chronically exposing the peripheral lung epithelia cell line, HPL-1D, to a low level of cadmium. Cells were chronically exposed to 5 ?M cadmium, a noncytotoxic level, and monitored for acquired cancer characteristics. By 20 weeks of continuous cadmium exposure, these chronic cadmium treated lung (CCT-LC) cells showed marked increases in secreted MMP-2 activity (3.5-fold), invasion (3.4-fold), and colony formation in soft agar (2-fold). CCT-LC cells were hyperproliferative, grew well in serum-free media, and overexpressed cyclin D1. The CCT-LC cells also showed decreased expression of the tumor suppressor genes p16 and SLC38A3 at the protein levels. Also consistent with an acquired cancer cell phenotype, CCT-LC cells showed increased expression of the oncoproteins K-RAS and N-RAS as well as the epithelial-to-mesenchymal transition marker protein Vimentin. Metallothionein (MT) expression is increased by cadmium, and is typically overexpressed in human lung cancers. The major MT isoforms, MT-1A and MT-2A were elevated in CCT-LC cells. Oxidant adaptive response genes HO-1 and HIF-1A were also activated in CCT-LC cells. Expression of the metal transport genes ZNT-1, ZNT-5, and ZIP-8 increased in CCT-LC cells culminating in reduced cadmium accumulation, suggesting adaptation to the metal. Overall, these data suggest that exposure of human lung epithelial cells to cadmium causes acquisition of cancer cell characteristics. Furthermore, transformation occurs despite the cell's ability to adapt to chronic cadmium exposure. - Highlights: Chronic cadmium exposure induces cancer cell characteristics in human lung cells. This provides an in vitro model of cadmium-induced human lung cell transformation. This occurred with general and lung specific changes typical for cancer cells. These findings add insight to the relationship between cadmium and lung cancer.

Person, Rachel J.; Tokar, Erik J.; Xu, Yuanyuan; Orihuela, Ruben; Ngalame, Ntube N. Olive; Waalkes, Michael P., E-mail: waalkes@niehs.nih.gov

2013-12-01T23:59:59.000Z

262

Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines  

SciTech Connect (OSTI)

The reninangiotensin system (RAS) in the brain is involved in the pathogenesis of hypertension. We hypothesized that inhibition of angiotensin-converting enzyme (ACE) in the hypothalamic paraventricular nucleus (PVN) attenuates angiotensin II (ANG II)-induced hypertension via restoring neurotransmitters and cytokines. Rats underwent subcutaneous infusions of ANG II or saline and bilateral PVN infusions of ACE inhibitor enalaprilat (ENL, 2.5 ?g/h) or vehicle for 4 weeks. ANG II infusion resulted in higher mean arterial pressure and cardiac hypertrophy as indicated by increased whole heart weight/body weight ratio, whole heart weight/tibia length ratio, left ventricular weight/tibia length ratio, and mRNA expressions of cardiac atrial natriuretic peptide and beta-myosin heavy chain. These ANG II-infused rats had higher PVN levels of glutamate, norepinephrine, tyrosine hydroxylase, pro-inflammatory cytokines (PICs) and the chemokine monocyte chemoattractant protein-1, and lower PVN levels of gamma-aminobutyric acid, interleukin (IL)-10 and the 67-kDa isoform of glutamate decarboxylase (GAD67), and higher plasma levels of PICs, norepinephrine and aldosterone, and lower plasma IL-10, and higher renal sympathetic nerve activity. However, PVN treatment with ENL attenuated these changes. PVN microinjection of ANG II induced increases in IL-1? and IL-6, and a decrease in IL-10 in the PVN, and pretreatment with angiotensin II type 1 receptor (AT1-R) antagonist losartan attenuated these changes. These findings suggest that ANG II infusion induces an imbalance between excitatory and inhibitory neurotransmitters and an imbalance between pro- and anti-inflammatory cytokines in the PVN, and PVN inhibition of the RAS restores neurotransmitters and cytokines in the PVN, thereby attenuating ANG II-induced hypertension and cardiac hypertrophy. - Highlights: Chronic ANG II infusion results in sympathetic hyperactivity and cardiac hypertrophy. PVN inhibition of ACE attenuates ANG II-induced hypertension and cardiac hypertrophy. PVN inhibition of ACE attenuates ANG II-induced imbalance of PVN neurotransmitters. PVN inhibition of ACE attenuates ANG II-induced imbalance of cytokines in the PVN. PVN blockade of AT1-R attenuates ANG II-induced imbalance of cytokines in the PVN.

Kang, Yu-Ming, E-mail: ykang@mail.xjtu.edu.cn [Department of Physiology and Pathophysiology, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an Jiaotong University School of Medicine, Xi'an 710061 (China); Zhang, Dong-Mei [Department of Physiology, Dalian Medical University, Dalian 116044 (China); Yu, Xiao-Jing; Yang, Qing; Qi, Jie; Su, Qing [Department of Physiology and Pathophysiology, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an Jiaotong University School of Medicine, Xi'an 710061 (China); Suo, Yu-Ping [Department of Obstetrics and Gynecology, Shanxi Provincial People's Hospital, Taiyuan 030012 (China); Yue, Li-Ying [Department of Physiology and Pathophysiology, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an Jiaotong University School of Medicine, Xi'an 710061 (China); Zhu, Guo-Qing [Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Physiology, Nanjing Medical University, Nanjing 210029 (China); Qin, Da-Nian, E-mail: dnqin@stu.edu.cn [Department of Physiology, Shantou University Medical College, Shantou 515041 (China)

2014-02-01T23:59:59.000Z

263

Cross-talk between non-genomic and genomic signalling pathways - Distinct effect profiles of environmental estrogens  

SciTech Connect (OSTI)

Estrogen receptor (ER) transcriptional cross-talk after activation by 17{beta}-estradiol (E2) has been studied in considerable detail, but comparatively little is known about the ways in which synthetic estrogen-like chemicals, so-called xenoestrogens, interfere with these signalling pathways. E2 can stimulate rapid, non-genomic signalling events, such as activation of the Src/Ras/Erk signalling pathway. We investigated how activation of this pathway by E2, the estrogenic environmental contaminants o,p'-DDT, {beta}-HCH and p,p'-DDE, and epidermal growth factor (EGF) influences the expression of ER target genes, such as TFF1, ER, PR, BRCA1 and CCND1, and the proliferation of breast cancer cells. Despite commonalities in their estrogenicity as judged by cell proliferation assays, the environmental contaminants exhibited striking differences in their non-genomic and genomic signalling. The gene expression profiles of o,p'-DDT and {beta}-HCH resembled the effects observed with E2. In the case of {beta}-HCH this is surprising, considering its reported lack of affinity to the 'classical' ER. The expression profiles seen with p,p'-DDE showed some similarities with E2, but overall, p,p'-DDE was a fairly weak transcriptional inducer of TFF1, ER, PR, BRCA1 and CCND1. We observed distinct differences in the non-genomic signalling of the tested compounds. p,p'-DDE was unable to stimulate Src and Erk1/Erk2 activations. The effects of E2 on Src and Erk1/Erk2 phosphorylation were transient and weak when compared to EGF, but {beta}-HCH induced strong and sustained activation of all tested kinases. Transcription of TFF1, ER, PR and BRCA1 by E2, o,p'-DDT and {beta}-HCH could be suppressed partially by inhibiting the Src/Ras/Erk pathway with PD 98059. However, this was not seen with p,p'-DDE. Our investigations show that the cellular activities of estrogens and xenoestrogens are the result of a combination of extranuclear (non-genomic) and nuclear (genomic) events and highlight the need to take non-genomic effects and signalling cross-talk into consideration, when screening for environmental estrogens. Otherwise, chemicals devoid of ER affinity, such as {beta}-HCH, but with an effect profile otherwise similar to estrogens might be overlooked in safety testing.

Silva, Elisabete, E-mail: elisabete.silva@pharmacy.ac.u [Centre for Toxicology, School of Pharmacy, University of London, 29-39 Brunswick Square, London, WC1N 1AX (United Kingdom); Kabil, Alena; Kortenkamp, Andreas [Centre for Toxicology, School of Pharmacy, University of London, 29-39 Brunswick Square, London, WC1N 1AX (United Kingdom)

2010-06-01T23:59:59.000Z

264

The oncogenic action of ionizing radiation on rat skin. Final progress report, May 1, 1990--April 30, 1992  

SciTech Connect (OSTI)

The multistage theory of carcinogenesis specifies that cells progress to cancer through a series of discrete, irreversible genetic alterations, but data on radiation-induced cancer incidence in rat skin suggests that an intermediate repairable alteration may occur. Data are presented on cancer induction in rat skin exposed to an electron beam (LET=0.34 keV/{mu}), a neon ion beam (LET=45) or an argon ion beam (LET=125). The rats were observed for tumors at least 78 weeks with squamous and basal cell carcinomas observed. The total cancer yield was fitted by the quadratic equation, and the equation parameters were estimated by linear regression for each type of radiation. Analysis of the DNA from the electron-induced carcinomas indicated that K-ras and/or c-myc oncogenes were activated. In situ hybridization indicated that the cancers contain subpopulations of cells with differing amounts of c-myc and H-ras amplification. The results are consistent with the idea that ionizing radiation produces stable, carcinogenically relevant lesions via 2 repairable events at low LET and via a non-repairable linked event pathway at high LET; either pathway may advance the cell by 1 stage. The proliferative response of rat epidermis following exposure to ionizing radiation was quantified by injection of {sup 14}C-thymidine. The return of these cells to S-phase a second time was detected by a second label ({sup 3}H). When the labeled cells were in G1-phase, the dorsal skin was irradiated with X-rays. All labeling indices were determined. The {sup 14}C labeling index was constant and unaffected by the radiation. The proportion of all cells entering S-phase averaged 3.5% at 18 hr and increased after 44, 52 and 75 hr to average levels of 11.8%, 5. 3%, and 6.6% at 0, 10 and 25 Gy respectively. The proportion of S-phase cells labeled with {sup 14}C increased after 42 hr and remained relatively constant thereafter.

Burns, F.J.; Garte, S.J.

1992-12-31T23:59:59.000Z

265

The oncogenic action of ionizing radiation on rat skin  

SciTech Connect (OSTI)

The multistage theory of carcinogenesis specifies that cells progress to cancer through a series of discrete, irreversible genetic alterations, but data on radiation-induced cancer incidence in rat skin suggests that an intermediate repairable alteration may occur. Data are presented on cancer induction in rat skin exposed to an electron beam (LET=0.34 keV/[mu]), a neon ion beam (LET=45) or an argon ion beam (LET=125). The rats were observed for tumors at least 78 weeks with squamous and basal cell carcinomas observed. The total cancer yield was fitted by the quadratic equation, and the equation parameters were estimated by linear regression for each type of radiation. Analysis of the DNA from the electron-induced carcinomas indicated that K-ras and/or c-myc oncogenes were activated. In situ hybridization indicated that the cancers contain subpopulations of cells with differing amounts of c-myc and H-ras amplification. The results are consistent with the idea that ionizing radiation produces stable, carcinogenically relevant lesions via 2 repairable events at low LET and via a non-repairable linked event pathway at high LET; either pathway may advance the cell by 1 stage. The proliferative response of rat epidermis following exposure to ionizing radiation was quantified by injection of [sup 14]C-thymidine. The return of these cells to S-phase a second time was detected by a second label ([sup 3]H). When the labeled cells were in G1-phase, the dorsal skin was irradiated with X-rays. All labeling indices were determined. The [sup 14]C labeling index was constant and unaffected by the radiation. The proportion of all cells entering S-phase averaged 3.5% at 18 hr and increased after 44, 52 and 75 hr to average levels of 11.8%, 5. 3%, and 6.6% at 0, 10 and 25 Gy respectively. The proportion of S-phase cells labeled with [sup 14]C increased after 42 hr and remained relatively constant thereafter.

Burns, F.J.; Garte, S.J.

1992-01-01T23:59:59.000Z

266

Molecular Dynamics - Solvated Interaction Energy Studies of Protein-Protein Interactions; The MP1-p14 Scaffolding Complex  

SciTech Connect (OSTI)

Using the MP1-p14 scaffolding complex from the mitogen-activated protein kinase signaling pathway as model system, we explored a structure-based computational protocol to probe and characterize binding affinity hot spots at protein-protein interfaces. Hot spots are located by virtual alanine-scanning consensus predictions over three different energy functions and two different single-structure representations of the complex. Refined binding affinity predictions for select hot-spot mutations are carried out by applying first-principle methods such as the molecular mechanics generalized Born surface area (MM-GBSA) and solvated interaction energy (SIE) to the molecular dynamics (MD) trajectories for mutated and wild-type complexes. Here, predicted hot-spot residues were actually mutated to alanine, and crystal structures of the mutated complexes were determined. Two mutated MP1-p14 complexes were investigated, the p14(Y56A)-mutated complex and the MP1(L63A, L65A)-mutated complex. Alternative ways to generate MD ensembles for mutant complexes, not relying on crystal structures for mutated complexes, were also investigated. The SIE function, fitted on protein-ligand binding affinities, gave absolute binding affinity predictions in excellent agreement with experiment and outperformed standard MM-GBSA predictions when tested on the MD ensembles of Ras-Raf and Ras-RalGDS protein-protein complexes. For wild-type and mutant MP1-p14 complexes, SIE predictions of relative binding affinities were supported by a yeast two-hybrid assay that provided semiquantitative relative interaction strengths. Results on the MP1-mutated complex suggested that SIE predictions deteriorate if mutant MD ensembles are approximated by just mutating the wild-type MD trajectory. The SIE data on the p14-mutated complex indicated feasibility for generating mutant MD ensembles from mutated wild-type crystal structure, despite local structural differences observed upon mutation. For energetic considerations, this would circumvent costly needs to produce and crystallize mutated complexes. The sensitized protein-protein interface afforded by the p14(Y56A) mutation identified here has practical applications in screening-based discovery of first-generation small-molecule hits for further development into specific modulators of the mitogen-activated protein kinase signaling pathway.

Cui,Q.; Sulea, T.; Schrag, J.; Munger, C.; Hung, M.; Naim, M.; Cygler, M.; Purisima, E.

2008-01-01T23:59:59.000Z

267

2010 Remediation Effectiveness Report for the U.S. Department of Energy Oak Ridge Reservation, Oak Ridge, Tennessee - Data and Evaluations  

SciTech Connect (OSTI)

Under the requirements of the Oak Ridge Reservation (ORR) Federal Facility Agreement (FFA) established between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency, (EPA) and the Tennessee Department of Environment and Conservation (TDEC) in 1992, all environmental restoration activities on the ORR are performed in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Since the 1990s, the environmental restoration activities have experienced a gradual shift from characterization to remediation. As this has occurred, it has been determined that the assessment of the individual and cumulative performance of all ORR CERCLA remedial actions (RAs) is most effectively tracked in a single document. The Remediation Effectiveness Report (RER) is an FFA document intended to collate all ORR CERCLA decision requirements, compare pre- and post-remediation conditions at CERCLA sites, and present the results of any required post-decision remediation effectiveness monitoring. First issued in 1997, the RER has been reissued annually to update the performance histories of completed actions and to add descriptions of new CERCLA actions. Monitoring information used in the 2010 RER to assess remedy performance was collected and/or compiled by DOE's Water Resources Restoration Program (WRRP). Only data used to assess performance of completed actions are provided. In addition to collecting CERCLA performance assessment data, the WRRP also collects baseline data to be used to gauge the effectiveness of future actions once implemented. These baseline data are maintained in the Oak Ridge Environmental Information System and will be reported in future RERs, as necessary, once the respective actions are completed. However, when insufficient data exist to assess the impact of the RAs, e.g., when the RA was only recently completed, a preliminary evaluation is made of early indicators of effectiveness at the watershed scale, such as contaminant trends at surface water integration points (IPs). Long-term stewardship (LTS) information used in this report is collected, compiled, and tracked by the WRRP in conjunction with the Bechtel Jacobs Company LLC (BJC) Surveillance and Maintenance (S&M) program, the BJC Radiation Protection Organization at East Tennessee Technology Park (ETTP), and the ETTP Environmental Compliance Program. Additionally, documentation verifying the implementation of administrative land use controls (LUCs) [i.e., property record restrictions, property record notices, zoning notices, and excavation/penetration permit (EPP) program] is also obtained from many sources throughout the fiscal year (FY), including County Register of Deeds offices for property record restrictions and property record notices, City Planning Commission for zoning notices, and BJC project engineers for EPP program verification. Copies of this documentation are obtained by the WRRP and maintained with the project RER files.

Bechtel Jacobs

2010-09-01T23:59:59.000Z

268

Guide to ground water remediation at CERCLA response action and RCRA corrective action sites  

SciTech Connect (OSTI)

This Guide contains the regulatory and policy requirements governing remediation of ground water contaminated with hazardous waste [including radioactive mixed waste (RMW)], hazardous substances, or pollutants/contaminants that present (or may present) an imminent and substantial danger. It was prepared by the Office of Environmental Policy and Assistance, RCRA/CERCLA Division (EH-413), to assist Environmental Program Managers (ERPMs) who often encounter contaminated ground water during the performance of either response actions under CERCLA or corrective actions under Subtitle C of RCRA. The Guide begins with coverage of the regulatory and technical issues that are encountered by ERPM`s after a CERCLA Preliminary Assessment/Site Investigation (PA/SI) or the RCRA Facility Assessment (RFA) have been completed and releases into the environment have been confirmed. It is based on the assumption that ground water contamination is present at the site, operable unit, solid waste management unit, or facility. The Guide`s scope concludes with completion of the final RAs/corrective measures and a determination by the appropriate regulatory agencies that no further response action is necessary.

NONE

1995-10-01T23:59:59.000Z

269

Remedial Action Plan and site design for stabilization of the inactive uranium mill tailings site at Falls City, Texas. Remedial action selection report: Attachment 2, Geology report; Attachment 3, Groundwater hydrology report; Attachment 4, Water resources protection strategy: Final report  

SciTech Connect (OSTI)

The uranium processing site near Falls City, Texas, was one of 24 inactive uranium mill sites designated to be remediated by the US Department of Energy (DOE) under Title I of the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA). The UMTRCA requires that the US Nuclear Regulatory Commission (NRC) concur with the DOE`s remedial action plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the US Environmental Protection Agency (EPA). The RAP, which includes this summary remedial action selection report (RAS), serves a two-fold purpose. First, it describes the activities proposed by the DOE to accomplish long-term stabilization and control of the residual radioactive materials at the inactive uranium processing site near Falls City, Texas. Second, this document and the remainder of the RAP, upon concurrence and execution by the DOE, the State of Texas, and the NRC, becomes Appendix B of the Cooperative Agreement between the DOE and the State of Texas.

Chernoff, A.R. [USDOE Albuquerque Field Office, NM (United States). Uranium Mill Tailings Remedial Action Project Office; Lacker, D.K. [Texas State Dept. of Health, Austin, TX (United States). Bureau of Radiation Control

1992-09-01T23:59:59.000Z

270

Remedial action plan and site design for stabilization of the inactive uranium mill tailings site at Falls City, Texas. Remedial action selection report, attachment 2, geology report; attachment 3, groundwater hydrology report; and attachment 4, water resources protection strategy. Final report  

SciTech Connect (OSTI)

The uranium processing site near Falls City, Texas, was one of 24 inactive uranium mill sites designated to be remediated by the U.S. Department of Energy (DOE) under Title I of the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA). The UMTRCA requires that the U.S. Nuclear Regulatory Commission (NRC) concur with the DOE`s remedial action plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the U.S. Environmental Protection Agency (EPA). The RAP, which includes this summary remedial action selection report (RAS), serves a two-fold purpose. First, it describes the activities proposed by the DOE to accomplish long-term stabilization and control of the residual radioactive materials at the inactive uranium processing site near Falls City, Texas. Second, this document and the remainder of the RAP, upon concurrence and execution by the DOE, the State of Texas, and the NRC, becomes Appendix B of the Cooperative Agreement between the DOE and the State of Texas.

NONE

1992-09-01T23:59:59.000Z

271

Remedial Action Plan and site design for stabilization of the inactive uranium mill tailings site at Falls City, Texas. [Uranium Mill Tailings Remedial Action (UMTRA) Project  

SciTech Connect (OSTI)

The uranium processing site near Falls City, Texas, was one of 24 inactive uranium mill sites designated to be remediated by the US Department of Energy (DOE) under Title I of the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA). The UMTRCA requires that the US Nuclear Regulatory Commission (NRC) concur with the DOE's remedial action plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the US Environmental Protection Agency (EPA). The RAP, which includes this summary remedial action selection report (RAS), serves a two-fold purpose. First, it describes the activities proposed by the DOE to accomplish long-term stabilization and control of the residual radioactive materials at the inactive uranium processing site near Falls City, Texas. Second, this document and the remainder of the RAP, upon concurrence and execution by the DOE, the State of Texas, and the NRC, becomes Appendix B of the Cooperative Agreement between the DOE and the State of Texas.

Chernoff, A.R. (USDOE Albuquerque Field Office, NM (United States). Uranium Mill Tailings Remedial Action Project Office); Lacker, D.K. (Texas State Dept. of Health, Austin, TX (United States). Bureau of Radiation Control)

1992-09-01T23:59:59.000Z

272

Remedial Action Plan and site design for stabilization of the inactive uranium mill tailings site at Durango, Colorado: Remedial action selection report. Revised final report  

SciTech Connect (OSTI)

The uranium mill tailings site near Durango, Colorado, was one of 24 inactive uranium mill sites designated to be remediated by the US Department of Energy (DOE) under the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA). Part of the UMTRCA requires that the US Nuclear Regulatory Commission (NRC) concur with the DOE`s Remedial Action Plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the US Environmental Protection Agency (EPA). Included in the RAP is this Remedial Action Selection Report (RAS), which has been developed to serve a two-fold purpose. First, it describes the activities that have been conducted by the DOE to accomplish remediation and long-term stabilization and control of the radioactive materials at the inactive uranium mill processing site near Durango, Colorado. Secondly, this document and the rest of the RAP, upon concurrence and execution by the DOE, the State of Colorado, and the NRC, become Appendix B of the Cooperative Agreement between the DOE and the State of Colorado.

Not Available

1991-12-01T23:59:59.000Z

273

Remedial Action Plan and site design for stabilization of the inactive uranium mill tailings site at Durango, Colorado: Remedial action selection report  

SciTech Connect (OSTI)

The uranium mill tailings site near Durango, Colorado, was one of 24 inactive uranium mill sites designated to be remediated by the US Department of Energy (DOE) under the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA). Part of the UMTRCA requires that the US Nuclear Regulatory Commission (NRC) concur with the DOE's Remedial Action Plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the US Environmental Protection Agency (EPA). Included in the RAP is this Remedial Action Selection Report (RAS), which has been developed to serve a two-fold purpose. First, it describes the activities that have been conducted by the DOE to accomplish remediation and long-term stabilization and control of the radioactive materials at the inactive uranium mill processing site near Durango, Colorado. Secondly, this document and the rest of the RAP, upon concurrence and execution by the DOE, the State of Colorado, and the NRC, become Appendix B of the Cooperative Agreement between the DOE and the State of Colorado.

Not Available

1991-12-01T23:59:59.000Z

274

Time-dependent restricted-active-space self-consistent-field singles method for many-electron dynamics  

E-Print Network [OSTI]

The time-dependent restricted-active-space self-consistent-field singles (TD-RASSCF-S) method is presented for investigating TD many-electron dynamics in atoms and molecules. Adopting the SCF notion from the muticonfigurational TD Hartree-Fock (MCTDHF) method and the RAS scheme (single-orbital excitation concept) from the TD configuration-interaction singles (TDCIS) method, the TD-RASSCF-S method can be regarded as a hybrid of them. We prove that, for closed-shell $N_{\\rm e}$-electron systems, the TD-RASSCF-S wave function can be fully converged using only $N_{\\rm e}/2+1\\le M\\le N_{\\rm e}$ spatial orbitals. Importantly, based on the TD variational principle, the converged TD-RASSCF-S wave function with $M= N_{\\rm e}$ is more accurate than the TDCIS wave function. The accuracy of the TD-RASSCF-S approach over the TDCIS is illustrated by the calculation of high-order harmonic generation spectra for one-dimensional models of atomic helium, beryllium, and carbon in an intense laser pulse. The electronic dynamics during the process is investigated by analyzing the behavior of electron density and orbitals. The TD-RASSCF-S method is accurate, numerically tractable, and applicable for large systems beyond the capability of the MCTDHF method.

Haruhide Miyagi; Lars Bojer Madsen

2014-05-21T23:59:59.000Z

275

Optical and infrared emission of H II complexes as a clue to PAHs lifecycle  

E-Print Network [OSTI]

We present an analysis of optical spectroscopy and infrared aperture photometry of more than 100 H II complexes in nine galaxies. Spectra obtained with the 6-m telescope of SAO RAS are used along with archival data from Spitzer and several ground-based telescopes to infer a strength of polycyclic aromatic hydrocarbon (PAH) emission, age, properties of the UV radiation field, and metallicity of studied H II complexes. Physical properties (age, radiation field parameters, metallicity) are related to the $F_{8}/F_{24}$ ratio used as a proxy for the PAH abundance in order to reveal factors that may influence the PAH evolution in H II complexes. The well-known correlation between the $F_{8}/F_{24}$ ratio and metallicity is confirmed in the studied complexes. The infrared flux ratio also correlates with the [O III]$\\lambda 5007/\\mathrm{H\\beta}$ ratio which is often considered as an indicator of the radiation field hardness, but this correlation seems to be a mere reflection of a correlation between [O III]$\\lambda ...

Khramtsova, M S; Lozinskaya, T A; Egorov, O V

2014-01-01T23:59:59.000Z

276

Rap G protein signal in normal and disordered lymphohematopoiesis  

SciTech Connect (OSTI)

Rap proteins (Rap1, Rap2a, b, c) are small molecular weight GTPases of the Ras family. Rap G proteins mediate diverse cellular events such as cell adhesion, proliferation, and gene activation through various signaling pathways. Activation of Rap signal is regulated tightly by several specific regulatory proteins including guanine nucleotide exchange factors and GTPase-activating proteins. Beyond cell biological studies, increasing attempts have been made in the past decade to define the roles of Rap signal in specific functions of normal tissue systems as well as in cancer. In the immune and hematopoietic systems, Rap signal plays crucial roles in the development and function of essentially all lineages of lymphocytes and hematopoietic cells, and importantly, deregulated Rap signal may lead to unique pathological conditions depending on the affected cell types, including various types of leukemia and autoimmunity. The phenotypical studies have unveiled novel, even unexpected functional aspects of Rap signal in cells from a variety of tissues, providing potentially important clues for controlling human diseases, including malignancy.

Minato, Nagahiro, E-mail: minato@imm.med.kyoto-u.ac.jp

2013-09-10T23:59:59.000Z

277

Fiscal Year 2008 Phased Construction Completion Report for EU Z2-33 in Zone 2, East Tennessee Technology Park, Oak Ridge, Tennessee  

SciTech Connect (OSTI)

The Record of Decision for Soil, Buried Waste, and Subsurface Structure Actions in Zone 2, East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2161&D2) (Zone 2 ROD) acknowledged that most of the 800 acres in Zone 2 were contaminated, but that sufficient data to confirm the levels of contamination were lacking. The Zone 2 ROD further specified that a sampling strategy for filling the data gaps would be developed. The Remedial Design Report/Remedial Action Work Plan for Zone 2 Soils, Slabs, and Subsurface Structures, East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2224&D3) (Zone 2 RDR/RAWP) defined the sampling strategy as the Dynamic Verification Strategy (DVS), generally following the approach used for characterization of the Zone 1 exposure units (EUs). The Zone 2 ROD divided the Zone 2 area into seven geographic areas and 44 EUs. To facilitate the data quality objectives (DQOs) of the DVS process, the Zone 2 RDR/RAWP regrouped the 44 EUs into 12 DQO scoping EU groups. These groups facilitated the DQO process by placing similar facilities and their support facilities together and allowing identification of data gaps. The EU groups were no longer pertinent after DQO planning was completed and characterization was conducted as areas became accessible. As the opportunity to complete characterization became available, the planned DVS program and remedial actions (RAs) were completed for EU Z2-33. Remedial action was also performed at two additional areas in adjacent EU Z2-42 because of their close proximity and similar nature to a small surface soil RA in EU Z2-33. Remedial actions for building slabs performed in EU Z2-33 during fiscal year (FY) 2007 were reported in the Fiscal Year 2007 Phased Construction Completion Report for the Zone 2 Soils, Slabs, and Subsurface Structures at East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2723&D1). Recommended RAs for EU Z2-42 were described in the Fiscal Year 2006 Phased Construction Completion Report for the Zone 2 Soils, Slabs, and Subsurface Structures at East Tennessee Technology Park, Oak Ridge, Tennessee (DOE/OR/01-2317&D2). Remedial actions performed in the Balance of Site (BOS) Laboratory Area of EU Z2-33 and two small areas in EU Z2-42 are described in Sects. 5 through 10 of this Phased Construction Completion Report (PCCR). The purpose of this PCCR is to address the following: (1) Document DVS characterization results for EU Z2-33; (2) Describe and document the risk evaluation and determine if the EU meets the Zone 2 ROD requirements for unrestricted industrial use to 10 ft bgs; (3) Identify additional areas not defined in the Zone 2 ROD that require remediation based on the DVS evaluation results; and (4) Describe RAs performed in the EU Z2-33 BOS Laboratory Area and two small areas in EU Z2-42. Approximately 18 acres in EU Z2-33 are addressed in this PCCR. Based on the results of the DVS evaluation and RAs performed, all 18 acres are recommended for unrestricted industrial use to 10 ft bgs. Three Federal Facility Agreement sites are addressed and recommended for no further action within this acreage, including: (1) K-1004-L Recirculating Cooling Water Lines Leak Sites; (2) K-1044 Heavy Equipment Repair Shop; and (3) K-1015-A Laundry Pit. Remedial actions for EU Z2-33 were developed in response to DVS characterization results described in the EU Z2-33 Technical Memorandum (Appendix A) and to support reindustrialization of the East Tennessee Technology Park as a commercial industrial park. Remediation criteria were designed for the protection of a future industrial worker who normally would not have the potential for exposure to soil below 10ft bgs. Accordingly, the Zone 2 ROD required land use controls to prevent disturbance of soils below 10 ft deep and to restrict future land use to industrial/commercial activities. In response to stakeholder comments, the U.S. Department of Energy agreed to re-evaluate the need for such land use restrictions. This document includes a screening evaluation to determine the likel

Bechtel Jacobs

2008-09-11T23:59:59.000Z

278

A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer We validate the use of specific anti-Nf1 antibodies for immunofluorescence studies. Black-Right-Pointing-Pointer We detect Nf1 in the cytoplasm and nucleus of CCF cells. Black-Right-Pointing-Pointer We demonstrate that Nf1 partially colocalizes with PML nuclear bodies. Black-Right-Pointing-Pointer We demonstrate that there is a direct interaction between a fraction of Nf1 and the PML bodies. -- Abstract: Neurofibromatosis type 1 is a common genetic disease that causes nervous system tumors, and cognitive deficits. It is due to mutations within the NF1 gene, which encodes the Nf1 protein. Nf1 has been shown to be involved in the regulation of Ras, cAMP and actin cytoskeleton dynamics. In this study, using immunofluorescence experiments, we have shown a partial nuclear localization of Nf1 in the astrocytoma cell line: CCF and we have demonstrated that Nf1 partially colocalizes with PML (promyelocytic leukemia) nuclear bodies. A direct interaction between Nf1 and the multiprotein complex has further been demonstrated using 'in situ' proximity ligation assay (PLA).

Godin, Fabienne; Villette, Sandrine; Vallee, Beatrice; Doudeau, Michel; Morisset-Lopez, Severine [Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique (CNRS), UPR 4301, Universite d'Orleans et INSERM, rue Charles Sadron, 45071 Orleans Cedex 2 (France)] [Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique (CNRS), UPR 4301, Universite d'Orleans et INSERM, rue Charles Sadron, 45071 Orleans Cedex 2 (France); Ardourel, Maryvonne; Hevor, Tobias [Laboratoire de Neurobiologie, Universite d'Orleans, BP 6759, 45067 Orleans Cedex 2 (France)] [Laboratoire de Neurobiologie, Universite d'Orleans, BP 6759, 45067 Orleans Cedex 2 (France); Pichon, Chantal [Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique (CNRS), UPR 4301, Universite d'Orleans et INSERM, rue Charles Sadron, 45071 Orleans Cedex 2 (France)] [Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique (CNRS), UPR 4301, Universite d'Orleans et INSERM, rue Charles Sadron, 45071 Orleans Cedex 2 (France); Benedetti, Helene, E-mail: helene.benedetti@cnrs-orleans.fr [Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique (CNRS), UPR 4301, Universite d'Orleans et INSERM, rue Charles Sadron, 45071 Orleans Cedex 2 (France)] [Centre de Biophysique Moleculaire, Centre National de la Recherche Scientifique (CNRS), UPR 4301, Universite d'Orleans et INSERM, rue Charles Sadron, 45071 Orleans Cedex 2 (France)

2012-02-24T23:59:59.000Z

279

Molecular genetics in affective illness  

SciTech Connect (OSTI)

Genetic transmission in manic depressive illness (MDI) has been explored in twins, adoption, association, and linkage studies. The X-linked transmission hypothesis has been tested by using several markers on chromosome X: Xg blood group, color blindness, glucose-6-phosphate dehydrogenase (G6PD), factor IX (hemophilia B), and DNA probes such as DXS15, DXS52, F8C, ST14. The hypothesis of autosomal transmission has been tested by association studies with the O blood group located on chromosome 9, as well as linkage studies on chromosome 6 with the Human Leucocyte Antigens (HLA) haplotypes and on Chromosome 11 with DNA markers for the following genes: D2 dopamine receptor, tyrosinase, C-Harvey-Ras-A (HRAS) oncogene, insuline (ins), and tyrosine hydroxylase (TH). Although linkage studies support the hypothesis of a major locus for the transmission of MDI in the Xq27-28 region, several factors are limiting the results, and are discussed in the present review. 105 refs., 1 fig., 2 tabs.

Mendlewicz, J.; Sevy, S.; Mendelbaum, K. (Erasme Univ. Hospital, Brussels (Belgium))

1993-01-01T23:59:59.000Z

280

3D Spectroscopy in the Virtual Observatory: Current Status  

E-Print Network [OSTI]

Three cornerstones for the 3D data support in the Virtual Observatory are: (1) data model to describe them, (2) data access services providing access to fully-reduced datasets, and (3) client applications which can deal with 3D data. Presently all these components became available in the VO. We demonstrate an application of the IVOA Characterisation data model to description of IFU and Fabry-Perot datasets. Two services providing SSA-like access to 3D-spectral data and Characterisation metadata have been implemented by us: ASPID-SR at SAO RAS for accessing IFU and Fabry-Perot data from the Russian 6-m telescope, and the Giraffe Archive at the VO Paris portal for the VLT FLAMES-Giraffe datasets. We have implemented VO Paris Euro3D Client, handling Euro3D FITS format, that interacts with CDS Aladin and ESA VOSpec using PLASTIC to display spatial and spectral cutouts of 3D datasets. Though the prototype we are presenting is yet rather simple, it demonstrates how 3D spectroscopic data can be fully integrated into the VO infrastructure.

Igor Chilingarian; Francois Bonnarel; Mireille Louys; Ivan Zolotukhin; Frederic Royer; Isabelle Jegouzo; Pierre Le Sidaner; Pierre Fernique; Thomas Boch

2007-11-02T23:59:59.000Z

Note: This page contains sample records for the topic "haiti hondu ras" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Time-dependent restricted-active-space self-consistent-field singles method for many-electron dynamics  

SciTech Connect (OSTI)

The time-dependent restricted-active-space self-consistent-field singles (TD-RASSCF-S) method is presented for investigating TD many-electron dynamics in atoms and molecules. Adopting the SCF notion from the muticonfigurational TD Hartree-Fock (MCTDHF) method and the RAS scheme (single-orbital excitation concept) from the TD configuration-interaction singles (TDCIS) method, the TD-RASSCF-S method can be regarded as a hybrid of them. We prove that, for closed-shell N{sub e}-electron systems, the TD-RASSCF-S wave function can be fully converged using only N{sub e}/2 + 1 ? M ? N{sub e} spatial orbitals. Importantly, based on the TD variational principle, the converged TD-RASSCF-S wave function with M = N{sub e} is more accurate than the TDCIS wave function. The accuracy of the TD-RASSCF-S approach over the TDCIS is illustrated by the calculation of high-order harmonic generation spectra for one-dimensional models of atomic helium, beryllium, and carbon in an intense laser pulse. The electronic dynamics during the process is investigated by analyzing the behavior of electron density and orbitals. The TD-RASSCF-S method is accurate, numerically tractable, and applicable for large systems beyond the capability of the MCTDHF method.

Miyagi, Haruhide; Bojer Madsen, Lars [Department of Physics and Astronomy, Aarhus University, 8000 Aarhus C (Denmark)] [Department of Physics and Astronomy, Aarhus University, 8000 Aarhus C (Denmark)

2014-04-28T23:59:59.000Z

282

ErbB receptors in the biology and pathology of the aerodigestive tract  

SciTech Connect (OSTI)

The most common sites of malignancies in the aerodigestive tract include the lung, head and neck and the esophagus. Esophageal adenocarcinomas (EA), esophageal squamous cell carcinomas (ESCC), and squamous cell carcinomas of the head and neck (SCCHN) are the primary focus of this review. Traditional treatment for aerodigestive tract cancers includes primary chemoradiotherapy (CRT) or surgical resection followed by radiation (or CRT). Recent developments in treatment have focused increasingly on molecular targeting strategies including cetuximab (a monoclonal antibody against epidermal growth factor receptor (EGFR)). Cetuximab was FDA approved in 2006 for treatment of SCCHN, underscoring the importance of understanding the biology of these malignancies. EGFR is a member of the ErbB family of growth factor receptor tyrosine kinases. The major pathways activated by ErbB receptors include Ras/Raf/MAPK; PI3K/AKT; PLC{gamma} and STATs, all of which lead to the transcription of target genes that may contribute to aerodigestive tumor progression. This review explores the expression of ErbB receptors in EA, ESCC and SCCHN and the signaling pathways of EGFR in SCCHN.

Morgan, Sarah [Department of Otolaryngology, University of Pittsburgh School of Medicine, 200 Lothrop Street (United States); Suite 500, Pittsburgh, PA 15213 (United States); Grandis, Jennifer R. [Department of Otolaryngology, University of Pittsburgh School of Medicine, 200 Lothrop Street (United States); Suite 500, Pittsburgh, PA 15213 (United States)], E-mail: jgrandis@pitt.edu

2009-02-15T23:59:59.000Z

283

Remedial action plan and site design for stabilization of the inactive uranium processing site at Naturita, Colorado. Remedial action selection report, Attachment 2, Geology report: Preliminary final  

SciTech Connect (OSTI)

The uranium processing site near Naturita, Colorado, is one of 24 inactive uranium mill sites designated to be cleaned up by the US Department of Energy (DOE) under the Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA), Public Law 95-604. Part of the UMTRCA requires that the US Nuclear Regulatory Commission (NRC) concur with the DOE`s remedial action plan (RAP) and certify that the remedial action conducted at the site complies with the standards promulgated by the US Environmental Protection Agency (EPA). Included in the RAP is this Remedial Action Selection Report (RAS), which serves two purposes. First, it describes the activities that are proposed by the DOE to accomplish remediation and long-term stabilization and control of the radioactive materials at the inactive uranium processing site near Naturita, Colorado. Second, this document and the rest of the RAP, upon concurrence and execution by the DOE, the state of Colorado, and the NRC, become Appendix B of the cooperative agreement between the DOE and the State of Colorado.

Not Available

1993-08-01T23:59:59.000Z

284

2011 Remediation Effectiveness Report for the U.S. Department of Energy Oak Ridge Reservation, Oak Ridge, Tennessee - Data and Evaluations  

SciTech Connect (OSTI)

Under the requirements of the Oak Ridge Reservation (ORR) Federal Facility Agreement (FFA) established between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency, (EPA) and the Tennessee Department of Environment and Conservation (TDEC) in 1992, all environmental restoration activities on the ORR are performed in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Since the 1990s, the environmental restoration activities have experienced a gradual shift from characterization to remediation. As this has occurred, it has been determined that the assessment of the individual and cumulative performance of all ORR CERCLA remedial actions (RAs) is most effectively tracked in a single document. The Remediation Effectiveness Report (RER) is an FFA document intended to collate all ORR CERCLA decision requirements, compare pre- and post-remediation conditions at CERCLA sites, and present the results of any required post-decision remediation effectiveness monitoring. First issued in 1997, the RER has been reissued annually to update the performance histories of completed actions and to add descriptions of new CERCLA actions. Monitoring information used in the 2011 RER to assess remedy performance was collected and/or compiled by DOE's Water Resources Restoration Program (WRRP). Only data used to assess performance of completed actions are provided. In addition to collecting CERCLA performance assessment data, the WRRP also collects baseline data to be used to gauge the effectiveness of future actions once implemented. These baseline data are maintained in the Oak Ridge Environmental Information System and will be reported in future RERs, as necessary, once the respective actions are completed. However, when insufficient data exist to assess the impact of the RAs, e.g., when the RA was only recently completed, a preliminary evaluation is made of early indicators of effectiveness at the watershed scale, such as contaminant trends at surface water integration points (IFs). Long-term stewardship (LTS) information used in this report is collected, compiled, and tracked by the WRRP in conjunction with the Bechtel Jacobs Company LLC (BJC) Surveillance and Maintenance (S&M) program, the BJC Radiation Protection Organization at East Tennessee Technology Park (ETTP), ETTP Environmental Compliance Program, B&W Y-12 Liquid Waste Treatment Operations, and UT Battelle Facilities Management Division. Additionally, documentation verifying the implementation of administrative land use controls (LUCs) [i.e., property record restrictions, property record notices, zoning notices, and excavation/penetration permit (EPP) program] is also obtained from many sources throughout the fiscal year (FY), including County Register of Deeds offices for property record restrictions and property record notices, City Planning Commission for zoning notices, and BJC project engineers for EPP program verification. Copies of this documentation are obtained by the WRRP and maintained with the project RER files.

Bechtel Jacobs

2011-03-01T23:59:59.000Z

285

Delphinidin inhibits cell proliferation and invasion via modulation of Met receptor phosphorylation  

SciTech Connect (OSTI)

The HGF/Met signaling pathway is deregulated in majority of cancers and is associated with poor prognosis in breast cancer. Delphinidin, present in pigmented fruits and vegetables possesses potent anti-oxidant, anti-inflammatory and anti-angiogenic properties. Here, we assessed the anti-proliferative and anti-invasive effects of delphinidin on HGF-mediated responses in the immortalized MCF-10A breast cell line. Treatment of cells with delphinidin prior to exposure to exogenous HGF resulted in the inhibition of HGF-mediated (i) tyrosyl-phosphorylation and increased expression of Met receptor, (ii) phosphorylation of downstream regulators such as FAK and Src and (iii) induction of adaptor proteins including paxillin, Gab-1 and GRB-2. In addition, delphinidin treatment resulted in significant inhibition of HGF-activated (i) Ras-ERK MAPKs and (ii) PI3K/AKT/mTOR/p70S6K pathways. Delphinidin was found to repress HGF-activated NF{kappa}B transcription with a decrease in (i) phosphorylation of IKK{alpha}/{beta} and I{kappa}B{alpha}, and (ii) activation and nuclear translocation of NF{kappa}B/p65. Inhibition of HGF-mediated membrane translocation of PKC{alpha} as well as decreased phosphorylation of STAT3 was further observed in delphinidin treated cells. Finally, decreased cell viability of Met receptor expressing breast cancer cells treated with delphinidin argues for a potential role of the agent in the prevention of HGF-mediated activation of various signaling pathways implicated in breast cancer.

Syed, Deeba N.; Afaq, Farrukh; Sarfaraz, Sami; Khan, Naghma; Kedlaya, Rajendra; Setaluri, Vijayasaradhi [Department of Dermatology, University of Wisconsin, Madison (United States); Mukhtar, Hasan [Department of Dermatology, University of Wisconsin, Madison (United States)], E-mail: hmukhtar@wisc.edu

2008-08-15T23:59:59.000Z

286

Unique Structural and Nucleotide Exchange Features of the Rho1 GTPase of Entamoeba histolytica  

SciTech Connect (OSTI)

The single-celled human parasite Entamoeba histolytica possesses a dynamic actin cytoskeleton vital for its intestinal and systemic pathogenicity. The E. histolytica genome encodes several Rho family GTPases known to regulate cytoskeletal dynamics. EhRho1, the first family member identified, was reported to be insensitive to the Rho GTPase-specific Clostridium botulinum C3 exoenzyme, raising the possibility that it may be a misclassified Ras family member. Here, we report the crystal structures of EhRho1 in both active and inactive states. EhRho1 is activated by a conserved switch mechanism, but diverges from mammalian Rho GTPases in lacking a signature Rho insert helix. EhRho1 engages a homolog of mDia, EhFormin1, suggesting a role in mediating serum-stimulated actin reorganization and microtubule formation during mitosis. EhRho1, but not a constitutively active mutant, interacts with a newly identified EhRhoGDI in a prenylation-dependent manner. Furthermore, constitutively active EhRho1 induces actin stress fiber formation in mammalian fibroblasts, thereby identifying it as a functional Rho family GTPase. EhRho1 exhibits a fast rate of nucleotide exchange relative to mammalian Rho GTPases due to a distinctive switch one isoleucine residue reminiscent of the constitutively active F28L mutation in human Cdc42, which for the latter protein, is sufficient for cellular transformation. Nonconserved, nucleotide-interacting residues within EhRho1, revealed by the crystal structure models, were observed to contribute a moderating influence on fast spontaneous nucleotide exchange. Collectively, these observations indicate that EhRho1 is a bona fide member of the Rho GTPase family, albeit with unique structural and functional aspects compared with mammalian Rho GTPases.

Bosch, Dustin E.; Wittchen, Erika S.; Qiu, Connie; Burridge, Keith; Siderovski, David P. (UNC)

2012-08-10T23:59:59.000Z

287

2,3,7,8-Tetrachlorodibenzo-p-dioxin causes increases in expression of c-erb-A and levels of protein-tyrosine kinases in selected tissues of responsive mouse strains  

SciTech Connect (OSTI)

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) administered in vivo causes drastic reduction in the weight of the mouse thymus at low doses the reduction becoming statistically significant after 2 days. To understand the cause for such thymic involution TCDD-evoked changes in various biochemical parameters in this tissue were examined. The most noticeable change was observed in the increased activity of specific protein-tyrosine kinases and protein kinase C and an increased level of p21{sup ras}-associated binding of ({sup 3}H)GTP. The above changes appear to be a selective effect on these special classes of proteins. It has become apparent that the rise in protein-tyrosine kinase activities becomes significant within 24 hr, whereas the rise in protein kinase C does not become significant until 48 hr. In view of similarities between TCDD and thyroid hormones in causing thymic involution, the levels of c-erb-A expression were assessed in the liver by using avian {sup 32}P-labeled v-erb-A probe and RNA transfer blot hybridization technique. The results clearly indicate that TCDD has the property to elevate levels of mRNA bearing homology to v-erb-A. Based on such observations a hypothesis has been proposed that TCDD owes its potency to its ability to stimulate the expression of one of a family of DNAs bearing homology to v-erb-A and that one of the major consequences of such an action is stimulation of various tyrosine kinases.

Bombick, D.W.; Jankun, J.; Tullis, K.; Matsumura, F. (Michigan State Univ., East Lansing (USA))

1988-06-01T23:59:59.000Z

288

US DOE-EM On-Site Disposal Cell Working Group - Fostering Communication On Performance Assessment Challenges  

SciTech Connect (OSTI)

On-site disposal cells are in use and being considered at several U.S. Department of Energy (USDOE) sites as the final disposition for large amounts of waste associated with cleanup of contaminated areas and facilities. These facilities are typically developed with regulatory oversight from States and/or the US Environmental Protection Agency (USEPA) in addition to USDOE. The facilities are developed to meet design standards for disposal of hazardous waste as well as the USDOE performance based standards for disposal of radioactive waste. The involvement of multiple and different regulators for facilities across separate sites has resulted in some differences in expectations for performance assessments and risk assessments (PA/RA) that are developed for the disposal facilities. The USDOE-EM Office of Site Restoration formed a working group to foster improved communication and sharing of information for personnel associated with these Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) disposal cells and work towards more consistent assumptions, as appropriate, for technical and policy considerations related to performance and risk assessments in support of a Record of Decision and Disposal Authorization Statement. The working group holds teleconferences, as needed, focusing on specific topics of interest. The topics addressed to date include an assessment of the assumptions used for performance assessments and risk assessments (PA/RAs) for on-site disposal cells, requirements and assumptions related to assessment of inadvertent intrusion, DOE Manual 435.1-1 requirements, and approaches for consideration of the long-term performance of liners and covers in the context of PAs. The working group has improved communication among the staff and oversight personnel responsible for onsite disposal cells and has provided a forum to identify and resolve common concerns.

Seitz, Roger R. [Savannah River Site (SRS), Aiken, SC (United States); Suttora, Linda C. [U.S. Department of Energy, Office of Site Restoration, Germantown, MD (United States); Phifer, Mark [Savannah River Site (SRS), Aiken, SC (United States)

2014-03-01T23:59:59.000Z

289

The RERTR Program : a status report.  

SciTech Connect (OSTI)

This paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners since its inception in 1978. A brief summary of the results that the program had attained by the end of 1997 is followed by a detailed review of the major events, findings, and activities that took place in 1998. The past year was characterized by exceptionally important accomplishments and events for the RERTR program. Four additional shipments of spent fuel from foreign research reactors were accepted by the U.S. Altogether, 2,231 spent fuel assemblies from foreign research reactors have been received by the U.S. under the acceptance policy. Fuel development activities began to yield solid results. Irradiations of the first two batches of microplates were completed. Preliminary postirradiation examinations of these microplates indicate excellent irradiation behavior of some of the fuel materials that were tested. These materials hold the promise of achieving the pro am goal of developing LEU research reactor fuels with uranium density in the 8-9 g /cm{sup 3} range. Progress was made in the Russian RERTR program, which aims to develop and demonstrate the technical means needed to convert Russian-supplied research reactors to LEU fuels. Feasibility studies for converting to LEU fuel four Russian-designed research reactors (IR-8 in Russia, Budapest research reactor in Hungary, MARIA in Poland, and WWR-SM in Uzbekistan) were completed. A new program activity began to study the feasibility of converting three Russian plutonium production reactors to the use of low-enriched U0{sub 2}-Al dispersion fuel, so that they can continue to produce heat and electricity without producing significant amounts of plutonium. The study of an alternative LEU core for the FRM-II design has been extended to address, with favorable results, the transient performance of the core under hypothetical accident conditions. A major milestone was accomplished in the development of a process to produce molybdenum-99 from fission targets utilizing LEU instead of HEU. Targets containing LEU metal foils were irradiated in the RAS-GAS reactor at BATAN, Indonesia, and molybdenum-99 was successfully extracted through the ensuing process. These are exciting times for the program and for all those involved in it, and last year's successes augur well for the future. However, as in the past, the success of the RERTR program will depend on the international friendship and cooperation that have always been its trademark.

Travelli, A.

1998-10-19T23:59:59.000Z

290

Progress of the RERTR program in 2001.  

SciTech Connect (OSTI)

This paper describes the 2001 progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners. Postirradiation examinations of microplates have continued to reveal excellent irradiation behavior of U-Mo dispersion fuels in a variety of compositions and irradiating conditions. Irradiation of two new batches of miniplates of greater sizes was completed in the ATR to investigate the swelling behavior of these fuels under prototypic conditions. These materials hold the promise of achieving the program goal of developing LEU research reactor fuels with uranium densities in the 8-9 g/cm{sup 3} range. Qualification of the U-Mo dispersion fuels has been delayed by a patent issue involving KAERI. Test fuel elements with uranium density of 6 g/cm{sup 3} are being fabricated by BWXT and are expected to begin undergoing irradiation in the HFR-Petten reactor around March 2003, with a goal of qualifying this fuel by mid-2005. U-Mo fuel with uranium density of 8-9 g/cm{sup 3} is expected to be qualified by mid-2007. Final irradiation tests of LEU {sup 99}Mo targets in the RAS-GAS reactor at BATAN, in Indonesia, had to be postponed because of the 9/11 attacks, but the results collected to date indicate that these targets will soon be ready for commercial production. Excellent cooperation is also in progress with the CNEA in Argentina, MDSN/AECL in Canada, and ANSTO in Australia. Irradiation testing of five WWR-M2 tube-type fuel assemblies fabricated by the NZChK and containing LEU UO{sub 2} dispersion fuel was successfully completed within the Russian RERTR program. A new LEU U-Mo pin-type fuel that could be used to convert most Russian-designed research reactors has been developed by VNIINM and is ready for testing. Four additional shipments containing 822 spent fuel assemblies from foreign research reactors were accepted by the U.S. by September 30, 2001. Altogether, 4,562 spent fuel assemblies from foreign research reactors had been received by that date by the U.S. under the FRR SNF acceptance policy. The RERTR program is aggressively pursuing qualification of high-density LEU U-Mo dispersion fuels, with the dual goal of enabling further conversions and of developing a substitute for LEU silicide fuels that can be more easily disposed of after expiration of the U.S. FRR SNF Acceptance Program. As in the past, the success of the RERTR program will depend on the international friendship and cooperation that has always been its trademark.

Travelli, A.

2002-03-07T23:59:59.000Z

291

Status and progress of the RERTR program in the year 2000.  

SciTech Connect (OSTI)

This paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners during the year 2000 and discusses the main activities planned for the year 2001. The past year was characterized by important accomplishments and events for the RERTR program. Four additional shipments containing 503 spent fuel assemblies from foreign research reactors were accepted by the U.S. Altogether, 3,740 spent fuel assemblies from foreign research reactors have been received by the U.S. under the acceptance policy. Postirradiation examinations of three batches of microplates have continued to reveal excellent irradiation behavior of U-MO dispersion fuels in a variety of compositions and irradiating conditions. h-radiation of two new batches of miniplates of greater sizes is in progress in the ATR to investigate me swelling behavior of these fuels under prototypic conditions. These materials hold the promise of achieving the program goal of developing LEU research reactor fuels with uranium densities in the 8-9 g /cm{sup 3} range. Qualification of the U-MO dispersion fuels is proceeding on schedule. Test fuel elements with 6 gU/cm{sup 3} are being fabricated by BWXT and are scheduled to begin undergoing irradiation in the HFR-Petten in the spring of 2001, with a goal of qualifying this fuel by the end of 2003. U-Mo with 8-9 gU/cm{sup 3} is planned to be qualified by the end of 2005. Joint LEU conversion feasibility studies were completed for HFR-Petten and for SAFARI-1. Significant improvements were made in the design of LEU metal-foil annular targets that would allow efficient production of fission {sup 99}Mo. Irradiations in the RAS-GAS reactor showed that these targets can formed from aluminum tubes, and that the yield and purity of their product from the acidic process were at least as good as those from the HEU Cintichem targets. Progress was made on irradiation testing of LEU UO{sub 2} dispersion fuel and on LEU conversion feasibility studies in the Russian RERTR program. Conversion of the BER-11reactor in Berlin, Germany, was completed and conversion of the La Reins reactor in Santiago, Chile, began. These are exciting times for the program. In the fuel development area, the RERTR program is aggressively pursuing qualification of high-density LEU U-Mo dispersion fuels, with the dual goal of enabling fi.uther conversions and of developing a substitute for LEU silicide fuels that can be more easily disposed of after expiration of the FRR SNF Acceptance Program. The {sup 99}Mo effort has reached the point where it appears feasible for all the {sup 99}Mo producers of the world to agree jointly to a common course of action leading to the elimination of HEU use in their processes. As in the past, the success of the RERTR program will depend on the international friendship and cooperation that has always been its trademark.

Travelli, A.

2000-09-28T23:59:59.000Z

292

Assssment and Mapping of the Riverine Hydrokinetic Resource in the Continental United States  

SciTech Connect (OSTI)

The U.S. Department of Energy (DOE) funded the Electric Power Research Institute and its collaborative partners, University of Alaska ? Anchorage, University of Alaska ? Fairbanks, and the National Renewable Energy Laboratory, to provide an assessment of the riverine hydrokinetic resource in the continental United States. The assessment benefited from input obtained during two workshops attended by individuals with relevant expertise and from a National Research Council panel commissioned by DOE to provide guidance to this and other concurrent, DOE-funded assessments of water based renewable energy. These sources of expertise provided valuable advice regarding data sources and assessment methodology. The assessment of the hydrokinetic resource in the 48 contiguous states is derived from spatially-explicit data contained in NHDPlus ?a GIS-based database containing river segment-specific information on discharge characteristics and channel slope. 71,398 river segments with mean annual flow greater than 1,000 cubic feet per second (cfs) mean discharge were included in the assessment. Segments with discharge less than 1,000 cfs were dropped from the assessment, as were river segments with hydroelectric dams. The results for the theoretical and technical resource in the 48 contiguous states were found to be relatively insensitive to the cutoff chosen. Raising the cutoff to 1,500 cfs had no effect on estimate of the technically recoverable resource, and the theoretical resource was reduced by 5.3%. The segment-specific theoretical resource was estimated from these data using the standard hydrological engineering equation that relates theoretical hydraulic power (Pth, Watts) to discharge (Q, m3 s-1) and hydraulic head or change in elevation (??, m) over the length of the segment, where ? is the specific weight of water (9800 N m-3): ??? = ? ? ?? For Alaska, which is not encompassed by NPDPlus, hydraulic head and discharge data were manually obtained from Idaho National Laboratory?s Virtual Hydropower Prospector, Google Earth, and U.S. Geological Survey gages. Data were manually obtained for the eleven largest rivers with average flow rates greater than 10,000 cfs and the resulting estimate of the theoretical resource was expanded to include rivers with discharge between 1,000 cfs and 10,000 cfs based upon the contribution of rivers in the latter flow class to the total estimate in the contiguous 48 states. Segment-specific theoretical resource was aggregated by major hydrologic region in the contiguous, lower 48 states and totaled 1,146 TWh/yr. The aggregate estimate of the Alaska theoretical resource is 235 TWh/yr, yielding a total theoretical resource estimate of 1,381 TWh/yr for the continental US. The technically recoverable resource in the contiguous 48 states was estimated by applying a recovery factor to the segment-specific theoretical resource estimates. The recovery factor scales the theoretical resource for a given segment to take into account assumptions such as minimum required water velocity and depth during low flow conditions, maximum device packing density, device efficiency, and flow statistics (e.g., the 5 percentile flow relative to the average flow rate). The recovery factor also takes account of ?back effects? ? feedback effects of turbine presence on hydraulic head and velocity. The recovery factor was determined over a range of flow rates and slopes using the hydraulic model, HEC-RAS. In the hydraulic modeling, presence of turbines was accounted for by adjusting the Manning coefficient. This analysis, which included 32 scenarios, led to an empirical function relating recovery factor to slope and discharge. Sixty-nine percent of NHDPlus segments included in the theoretical resource estimate for the contiguous 48 states had an estimated recovery factor of zero. For Alaska, data on river slope was not readily available; hence, the recovery factor was estimated based on the flow rate alone. Segment-specific estimates of the theoretical resource were multiplied by the corresponding recovery factor to estimate

Jacobson, Paul T. [Electric Power Research Institute; Ravens, Thomas M. [University of Alaska Anchorage; Cunningham, Keith W. [University of Alaska Fairbanks; Scott, George [National Renewable Energy Laboratory

2012-12-14T23:59:59.000Z