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Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

An HIV Vaccine — Challenges and Prospects  

Science Journals Connector (OSTI)

...successful human vaccines, HIV quickly integrates itself into the DNA of the host cell, where, in some cells, it remains latent and essentially invisible to the immune system. Because latency is established very early — within days to weeks after infection — the window of opportunity wherein HIV... An HIV vaccine has thus far been elusive. Drs. Margaret Johnston and Anthony Fauci remain cautiously optimistic that a substantial increase in our understanding of HIV infection and disease will lead to creative ideas about how to design an effective HIV ...

Johnston M.I.; Fauci A.S.

2008-08-28T23:59:59.000Z

2

The Search for Effective HIV Vaccines  

Science Journals Connector (OSTI)

...to do with an evolving understanding of the routes of infection. Although many people become infected through the bloodstream, 90 percent of HIV infections are contracted through sexual transmission, with the virus crossing the mucosal tissues that line the genital tract, the rectum, and other body... As we continue to struggle to contain the pandemic of our age, scientists are exploring vaccines that do not prevent initial infection but may prevent or limit viral replication and delay disease progression. Dr. Howard Markel writes that when it comes to ...

Markel H.

2005-08-25T23:59:59.000Z

3

HIV immunity study could pave way for vaccine development  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Scientists among duke-led consortium HIV immunity study could pave way for vaccine development Two scientists are among the team recently funded to explore ways to create the...

4

The effects of HIV Tat DNA on regulating the immune response of HIV DNA vaccine in mice  

Science Journals Connector (OSTI)

HIV trans-activator protein (Tat) is the crucial factor to control HIV transcription, and is usually considered as an important immunogen for the design of HIV vaccine. Recent studies reported some special bio-ac...

Ye Liu; Fusheng Li; Zhi Qi; Yanling Hao; Kunxue Hong; Yong Liu…

2013-09-01T23:59:59.000Z

5

Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1  

Science Journals Connector (OSTI)

Femtosecond X-ray crystallography allows structural analysis of a difficult-to-crystallize fusion protein that is a potential component of a candidate HIV-1 subunit vaccine.

Lee, H.-H.

2014-08-20T23:59:59.000Z

6

Closer to HIV vaccine goal with new insight into viral factors  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Closer to HIV vaccine goal with new insight into viral factors Closer to HIV vaccine goal with new insight into viral factors New insight into viral factors that facilitate HIV transmission Understanding viral factors that facilitate transmission of HIV infection is critical to developing vaccines. February 14, 2012 Scientists work at the National Stable Isotope Resource LANL scientists found that the infected donor's predominant virus subpopulation in the genital tract differed from that in the blood. Comparing the HIV sequence population in each newly infected partner with that in the genital tract of the transmitting partner revealed that the transmitted variant was genetically distinct from the donor's predominant genital-tract variants. The results imply that a selective process, rather than a random one, determines the transmitted or founder virus.

7

Expanded breadth of the T-cell response to mosaic HIV-1 envelope DNA vaccination  

SciTech Connect (OSTI)

An effective AIDS vaccine must control highly diverse circulating strains of HIV-1. Among HIV -I gene products, the envelope (Env) protein contains variable as well as conserved regions. In this report, an informatic approach to the design of T-cell vaccines directed to HIV -I Env M group global sequences was tested. Synthetic Env antigens were designed to express mosaics that maximize the inclusion of common potential Tcell epitope (PTE) 9-mers and minimize the inclusion of rare epitopes likely to elicit strain-specific responses. DNA vaccines were evaluated using intracellular cytokine staining (ICS) in inbred mice with a standardized panel of highly conserved 15-mer PTE peptides. I, 2 and 3 mosaic sets were developed that increased theoretical epitope coverage. The breadth and magnitude ofT-cell immunity stimulated by these vaccines were compared to natural strain Env's; additional comparisons were performed on mutant Env's, including gpl60 or gpl45 with or without V regions and gp41 deletions. Among them, the 2 or 3 mosaic Env sets elicited the optimal CD4 and CD8 responses. These responses were most evident in CD8 T cells; the 3 mosaic set elicited responses to an average of 8 peptide pools compared to 2 pools for a set of3 natural Env's. Synthetic mosaic HIV -I antigens can therefore induce T-cell responses with expanded breadth and may facilitate the development of effective T -cell-based HIV -1 vaccines.

Korber, Bette [Los Alamos National Laboratory; Fischer, William [Los Alamos National Laboratory; Wallstrom, Timothy [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

8

For personal use. Only reproduce with permission from Elsevier Ltd. Most current candidate HIV vaccines seem to produce little  

E-Print Network [OSTI]

vaccines seem to produce little protection against infection, but reduce viral load and slow the decline the following question: could disease-modifying HIV vaccines cause population-level perversity (ie, increase--we show that disease- modifying vaccines that provide only a low degree of protection against infection

Blower, Sally

9

Evolving T-cell vaccine strategies for HIV, the virus with a thousand faces  

SciTech Connect (OSTI)

HIV's rapid global spread and the human suffering it has left in its wake have made AIDS a global heath priority for the 25 years since its discovery. Yet its capacity to rapidly evolve has made combating this virus a tremendous challenge. The obstacles to creating an effective HIV vaccine are formidable, but there are advances in the field on many fronts, in terms of novel vectors, adjuvants, and antigen design strategies. SIV live attenuated vaccine models are able to confer protection against heterologous challenge, and this continues to provide opportunities to explore the biological underpinnings of a protective effect (9). More indirect, but equally important, is new understanding regarding the biology of acute infection (43), the role of immune response in long-term non-progression (6,62, 81), and defining characteristics of broadly neutralizing antibodies (4). In this review we will focus on summarizing strategies directed towards a single issue, that of contending with HIV variation in terms of designing aT-cell vaccine. The strategies that prove most effective in this area can ultimately be combined with the best strategies under development in other areas, with the hope of ultimately converging on a viable vaccine candidate. Only two large HIV vaccine efficacy trials have been completed and both have failed to prevent infection or confer a benefit to infected individual (23,34), but there is ample reason to continue our efforts. A historic breakthrough came in 1996, when it was realized that although the virus could escape from a single antiretroviral (ARV) therapy, it could be thwarted by a combination of medications that simultaneously targeted different parts of the virus (HAART) (38). This revelation came after 15 years of research, thought, and clinical testing; to enable that vital progress the research and clinical communities had to first define and understand, then develop a strategy to counter, the remarkable evolutionary potential of the virus. HAART, for the first time, provided an effective treatment to help those with living with HIV stay healthy. Nonetheless, the treatment has limitations. People with HIV face a lifetime of expensive daily multi-drug regimens, often with side effects; drug resistance at the individual and population level are issues (56); and universal access, despite substantial progress, is a dream not yet realized for many of the millions of the world's poor who are living with HIV (68). These issues, combined with the growing numbers of people infected globally and impact of HIV on society, make the development of an HIV vaccine or a prophylactic prevention strategy a crucial if elusive goal. In some ways, the history of HIV vaccine deVelopment has paralleled the early stages of designing effective therapy. We had to test the simple strategies first, but meanwhile the story of the impact of diversity from an immunological perspective is still unfolding, and novel ideas countermeasures are being explored.

Korber, Bette [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

10

Research deciphers HIV attack plan  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

deciphers HIV attack plan Research deciphers HIV attack plan These findings will help inform vaccine design and interpretation of vaccine trials, and provide new insights...

11

E-Print Network 3.0 - anti-hiv drug regimens Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

body's natural anti-HIV immune... , there are no therapeutic HIV vaccines approved by the Food and DrugAdministration (FDA). However, therapeutic HIV vaccines... response, people...

12

Vaccine 29 (2011) 56115622 Contents lists available at ScienceDirect  

E-Print Network [OSTI]

antiviral immunity, the RM were immunized with multimeric HIV clade C (HIV-C) gp160 and HIV Tat. SIV Gag.elsevier.com/locate/vaccine Prime­boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 Replication-competent adenovirus Live oral vaccine HIV/AIDS vaccine Multimeric HIV clade C gp160 Prime

Lieberman, Judy

13

E-Print Network 3.0 - appreciating hiv-1 diversity Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

120 Vaccine to Prevent HIV-1 Infection The rgp120 HIV... virus type 1 (HIV-1) ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

14

E-Print Network 3.0 - attenuated candidate vaccine Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of effect... OF CANDIDATE HIV VACCINES The first 2 phase 3 trials of HIV ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

15

E-Print Network 3.0 - attenuated live-virus vaccine Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

virus (HIV) vaccines are unlikely to prevent acquisition of HIV in all Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

16

E-Print Network 3.0 - amastigotes enhance hiv-1 Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

120 Vaccine to Prevent HIV-1 Infection The rgp120 HIV... virus type 1 ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

17

Cattle Vaccines  

E-Print Network [OSTI]

Vaccines deliver antigens that stimulate the body's production of antibodies in response to disease. Cattle can be vaccinated with noninfectious or infectious vaccines. The types of vaccine products, proper handling of vaccines, and vaccination...

Faries Jr., Floron C.

2005-11-11T23:59:59.000Z

18

E-Print Network 3.0 - attenuated live vaccine Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of a live attenuated HIV... vaccine in macaques have clearly demonstrated the ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

19

E-Print Network 3.0 - assay chembio hiv Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

In... 654 JID 2005:191 (1 March) rgp120 HIV Vaccine Study Group M A ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

20

Design of HIV Vaccine Trials JID 2003:188 (15 July) 179 M A J O R A R T I C L E  

E-Print Network [OSTI]

Surrogate End Points in Phase 3 Trials Peter B. Gilbert,1 Victor G. DeGruttola,3 Michael G. Hudgens,1 Steven and Prevention, Fred Hutchinson Cancer Research Center, and 2 Department of Microbiology, University to L.C.). Reprints or correspondence: Dr. Peter Gilbert, Statistical Center for HIV/AIDS Research

Gilbert, Peter

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity  

Science Journals Connector (OSTI)

...either air or nitrogen gas. The immersion depth...mutant Fv4E10 binding drives conformational changes...NAb responses during natural infection (3, 19...antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine...

Hengyu Xu; Likai Song; Mikyung Kim; Margaret A. Holmes; Zane Kraft; George Sellhorn; Ellis L. Reinherz; Leonidas Stamatatos; Roland K. Strong

2009-11-11T23:59:59.000Z

22

Ebolavirus Vaccines  

Science Journals Connector (OSTI)

Ebolaviruses cause a severe hemorrhagic fever in humans and non-human primates, with case fatalities of up to 90%. There are currently no approved therapeutics or vaccines available for these viruses. However,...

Thomas Hoenen PhD

2013-01-01T23:59:59.000Z

23

Technical, economic, and clinical challenges to the development of new biomaterials-based vaccines  

E-Print Network [OSTI]

Research into novel vaccine methods is becoming increasingly important for the potential treatment of widespread diseases such as cancer, HIV, and malaria. Members of the Irvine laboratory have developed a hydrogel and ...

Huffman, Kathleen Renee

2005-01-01T23:59:59.000Z

24

E-Print Network 3.0 - adjuvanted hiv envelope Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

654 JID 2005:191 (1 March) rgp120 HIV Vaccine Study Group M A J O R A ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

25

Impact of Clade, Geography, and Age of the Epidemic on HIV-1 Neutralization by Antibodies  

Science Journals Connector (OSTI)

...glycoproteins: fusogens, antigens, and immunogens. Science 280 :1884-1888. doi: 10.1126/science.280.5371.1884 . 2. Hemelaar, J . 2013...HIV-1 vaccine development and therapy. Science 341 :1199-1204. doi: 10.1126/science...

Peter Hraber; Bette T. Korber; Alan S. Lapedes; Robert T. Bailer; Michael S. Seaman; Hongmei Gao; Kelli M. Greene; Francine McCutchan; Carolyn Williamson; Jerome H. Kim; Sodsai Tovanabutra; Beatrice H. Hahn; Ronald Swanstrom; Michael M. Thomson; Feng Gao; Linda Harris; Elena Giorgi; Nicholas Hengartner; Tanmoy Bhattacharya; John R. Mascola; David C. Montefiori

2014-08-20T23:59:59.000Z

26

Cancer vaccines: Material breach  

Science Journals Connector (OSTI)

... Willem Overwijk, a tumour immunologist who studies melanoma vaccines at MD Anderson Cancer Center in Houston, ...

Elie Dolgin

2013-12-18T23:59:59.000Z

27

Envelope Deglycosylation Enhances Antigenicity of HIV-1 gp41 Epitopes for Both Broad Neutralizing Antibodies and Their Unmutated Ancestor Antibodies  

E-Print Network [OSTI]

The HIV-1 gp41 envelope (Env) membrane proximal external region (MPER) is an important vaccine target that in rare subjects can elicit neutralizing antibodies. One mechanism proposed for rarity of MPER neutralizing antibody generation is lack...

Ma, Ben-Jiang; Alam, S. Munir; Go, Eden P.; Lu, Xiaozhi; Desaire, Heather; Tomaras, Georgia D.; Bowman, Cindy; Sutherland, Laura L.; Scearce, Richard M.; Santra, Sampa; Letivn, Norman L.; Kepler, Thomas B.; Liao, Hua-Xin; Haynes, Barton F.

2011-09-01T23:59:59.000Z

28

Distinct Mechanisms Regulate Exposure of Neutralizing Epitopes in the V2 and V3 Loops of HIV-1 Envelope  

Science Journals Connector (OSTI)

...donor reveal a new HIV-1 vaccine target. Science 326 :285-289. doi: 10.1126/science.1178746 . 10. Bonsignori, M , KK Hwang...glycosylated soluble cleaved HIV-1 envelope trimer. Science 342 :1484-1490. doi: 10.1126/science...

Chitra Upadhyay; Luzia M. Mayr; Jing Zhang; Rajnish Kumar; Miroslaw K. Gorny; Arthur Nádas; Susan Zolla-Pazner; Catarina E. Hioe

2014-08-27T23:59:59.000Z

29

Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors  

Science Journals Connector (OSTI)

...sequence, to trigger and drive the development of naive...antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine...Distance-scaled, finite ideal-gas reference state improves...be used to trigger and drive the development of memory...

Mattia Bonsignori; Kwan-Ki Hwang; Xi Chen; Chun-Yen Tsao; Lynn Morris; Elin Gray; Dawn J. Marshall; John A. Crump; Saidi H. Kapiga; Noel E. Sam; Faruk Sinangil; Marie Pancera; Yang Yongping; Baoshan Zhang; Jiang Zhu; Peter D. Kwong; Sijy O'Dell; John R. Mascola; Lan Wu; Gary J. Nabel; Sanjay Phogat; Michael S. Seaman; John F. Whitesides; M. Anthony Moody; Garnett Kelsoe; Xinzhen Yang; Joseph Sodroski; George M. Shaw; David C. Montefiori; Thomas B. Kepler; Georgia D. Tomaras; S. Munir Alam; Hua-Xin Liao; Barton F. Haynes

2011-07-27T23:59:59.000Z

30

Towards universal influenza vaccines?  

Science Journals Connector (OSTI)

...taking place in the field of vaccine biotechnology...development remarks production of seed strains...site-directed mutagenesis production platform use of...attenuated vaccines production of recombinant proteins...adjuvants use of oil-in-water adjuvants...Organization 2011 Cumulative number of confirmed...

2011-01-01T23:59:59.000Z

31

Neutron guide  

DOE Patents [OSTI]

A neutron guide in which lengths of cylindrical glass tubing have rectangular glass plates properly dimensioned to allow insertion into the cylindrical glass tubing so that a sealed geometrically precise polygonal cross-section is formed in the cylindrical glass tubing. The neutron guide provides easier alignment between adjacent sections than do the neutron guides of the prior art.

Greene, Geoffrey L. (Los Alamos, NM)

1999-01-01T23:59:59.000Z

32

Global Health: Designing Tomorrow's Vaccines  

Science Journals Connector (OSTI)

...million infections in the 20th century in the United States, but vaccines have since rendered them uncommon (Table 1). The success of this public health intervention emanates not only from the identification of effective vaccines but also from a robust infrastructure for vaccine manufacturing, regulatory... Vaccines are some of the most cost-effective treatments in medicine. This article reviews new strategies being applied to develop vaccines for diseases that have not been susceptible to this therapeutic approach.

Nabel G.J.

2013-02-07T23:59:59.000Z

33

Acquisition Guide  

Broader source: Energy.gov (indexed) [DOE]

_____Chapter 15.4-4 (July 2010) _____Chapter 15.4-4 (July 2010) GENERAL GUIDE FOR TECHNICAL ANALYSIS OF COST PROPOSALS FOR ACQUISITION CONTRACTS Acquisition Guide _____________________________________________________________ _______________________________________________________Chapter 15.4-4 (July 2010) TABLE OF CONTENT CHAPTER 1 - INTRODUCTION KEY CONCEPTS ........................................................................................1 LIST OF ACRONYMS...............................................................................1 RELATIONSHIP OF TECHNICAL ANALYSIS TO COST ANALYSIS ..................................2 RESPONSIBILITIES IN EVALUATING CONTRACTOR PROPOSALS ..................................2

34

Nonneutralizing Functional Antibodies: a New “Old” Paradigm for HIV Vaccines  

Science Journals Connector (OSTI)

...Souza, B Korber, R Koup, RT Bailer, JR Mascola, A Pinter...K Stanley, AG McNally, J Liu, P Abbink...Izulla, J Kimani, R Kaul, AS Fauci...M Pascuccio, R Gopaul, J McNally, CC Cruz, N Censoplano...Mathieson, M Marovich, JR Currier and JH Kim...

Jean-Louis Excler; Julie Ake; Merlin L. Robb; Jerome H. Kim; Stanley A. Plotkin

2014-06-11T23:59:59.000Z

35

Vaccines and global health  

Science Journals Connector (OSTI)

...been an appropriate, rational process for global priority setting...recs/acip/downloads/mtg-slides-oct10/02-3-mening-CostEffect...comparing choices is found, the process of new vaccine introduction...antigen through the complicated process from first identification to...

2011-01-01T23:59:59.000Z

36

Password Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Department of Energy (DOE) Guide provides detailed guidance to supplement DOE N 205.3, Password Generation, Protection, and Use. No cancellations. Canceled by DOE N 205.18

1999-11-23T23:59:59.000Z

37

Acquisition Guide  

Broader source: Energy.gov (indexed) [DOE]

Chapter 15.4-4 (December 2010) Chapter 15.4-4 (December 2010) GENERAL GUIDE FOR TECHNICAL ANALYSIS OF COST PROPOSALS FOR ACQUISITION CONTRACTS Acquisition Guide _____________________________________________________________ __________________________________________________Chapter 15.4-4 (November 2010) TABLE OF CONTENT CHAPTER 1 - INTRODUCTION KEY CONCEPTS ........................................................................................1 LIST OF ACRONYMS...............................................................................1 RELATIONSHIP OF TECHNICAL ANALYSIS TO COST ANALYSIS ..................................2 RESPONSIBILITIES IN EVALUATING CONTRACTOR PROPOSALS ..................................2 CHAPTER 2 - PREPARING TO EVALUATE A PROPOSAL

38

Candidate mosaic proteins for a pan-filoviral cytotoxic T-Cell lymphocyte vaccine  

SciTech Connect (OSTI)

The extremely high fatality rates of many filovirus (FILV) strains the recurrent but rarely identified origin of human epidemics, the only partly identified viral reservoirs and the continuing non-human primate epizootics in Africa make a broadly-protective filovirus vaccine highly desirable. Cytotoxic T-cells (CTL) have been shown to be protective in mice, guinea pigs and non-human primates. In murine models the cytotoxic T-cell epitopes that are protective against Ebola virus have been mapped and in non-human primates CTL-mediated protection between viral strains (John Dye: specify) has been demonstrated using two filoviral proteins, nucleoprotein (NP) and glycoprotein (GP). These immunological results suggest that the CTL avenue of immunity deserves consideration for a vaccine. The poorly-understood viral reservoirs means that it is difficult to predict what strains are likely to cause epidemics. Thus, there is a premium on developing a pan-filoviral vaccine. The genetic diversity of FILV is large, roughly the same scale as human immunodeficiency virus (HIV). This presents a serious challenge for the vaccine designer because a traditional vaccine aspiring to pan-filoviral coverage is likely to require the inclusion of many antigenic reagents. A recent method for optimizing cytotoxic T-cell lymphocyte epitope coverage with mosaic antigens was successful in improving potential CTL epitope coverage against HIV and may be useful in the context of very different viruses, such as the filoviruses discussed here. Mosaic proteins are recombinants composed of fragments of wild-type proteins joined at locations resulting in exclusively natural k-mers, 9 {le} k {le} 15, and having approximately the same length as the wild-type proteins. The use of mosaic antigens is motivated by three conjectures: (1) optimizing a mosaic protein to maximize coverage of k-mers found in a set of reference proteins will give better odds of including broadly-protective CTL epitopes in a vaccine than is possible with a wild-type protein, (2) reducing the number of low-prevalence k-mers minimizes the likelihood of undesirable immunodominance, and (3) excluding exogenous k-mers will result in mosaic proteins whose processing for presentation is close to what occurs with wild-type proteins. The first and second applications of the mosaic method were to HIV and Hepatitis C Virus (HCV). HIV is the virus with the largest number of known sequences, and consequently a plethora of information for the CTL vaccine designer to incorporate into their mosaics. Experience with HIV and HCV mosaics supports the validity of the three conjectures above. The available FILV sequences are probably closer to the minimum amount of information needed to make a meaningful mosaic vaccine candidate. There were 532 protein sequences in the National Institutes of Health GenPept database in November 2007 when our reference set was downloaded. These sequences come from both Ebola and Marburg viruses (EBOV and MARV), representing transcripts of all 7 genes. The coverage of viral diversity by the 7 genes is variable, with genes 1 (nucleoprotein, NP), 4 (glycoprotein, GP; soluble glycoprotein, sGP) and 7 (polymerase, L) giving the best coverage. Broadly-protective vaccine candidates for diverse viruses, such as HIV or Hepatitis C virus (HCV) have required pools of antigens. FILV is similar in this regard. While we have designed CTL mosaic proteins using all 7 types of filoviral proteins, only NP, GP and L proteins are reported here. If it were important to include other proteins in a mosaic CTL vaccine, additional sequences would be required to cover the space of known viral diversity.

Fenimore, Paul W [Los Alamos National Laboratory; Fischer, William M [Los Alamos National Laboratory; Kuiken, Carla [Los Alamos National Laboratory; Foley, Brian T [Los Alamos National Laboratory; Thurmond, J R [Los Alamos National Laboratory; Yusim, K [Los Alamos National Laboratory; Korber, B T [Los Alamos National Laboratory

2008-01-01T23:59:59.000Z

39

Influenza Cell-Culture Vaccine Production  

Science Journals Connector (OSTI)

Vaccine seed strains are distributed to the vaccine producers by WHO Influenza reference centers in order to evaluate their suitability for vaccine production. Factors such as yield when grown in cell...

Markus Hilleringmann PhD; Björn Jobst PhD; Barbara C. Baudner PhD

2014-01-01T23:59:59.000Z

40

User Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Guide Guide User Guide Print 1. Apply for Beam Time Submit a new proposal or a Beam Time Request (BTR) using an existing active proposal. 2. Establish a User Agreement Your institute must have a signed agreement with Berkeley Lab before you may do work at the ALS. 3. Complete Experiment Safety Documentation and Review Safety for Users Safety documentation must be completed and reviewed before your beam time. Experiments involving any biological material or radioactive material require more review steps so please allow several weeks for these. 4. Register with the User Office New and returning users need to register with the User Office TWO weeks before arriving at the ALS. Users arriving out of regular office hours must either have a valid Berkeley Lab ID badge, or have completed registration to be granted access to the ALS.

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Rapid selection of escape mutants by the first CD8 T cell responses in acute HIV-1 infection  

SciTech Connect (OSTI)

The recent failure of a vaccine that primes T cell responses to control primary HIV-1 infection has raised doubts about the role of CD8+ T cells in early HIV-1 infection. We studied four patients who were identified shortly after HIV-1 infection and before seroconversion. In each patient there was very rapid selection of multiple HIV-1 escape mutants in the transmitted virus by CD8 T cells, including examples of complete fixation of non-synonymous substitutions within 2 weeks. Sequencing by single genome amplification suggested that the high rate of virus replication in acute infection gave a selective advantage to virus molecules that contained simultaneous and gained sequential T cell escape mutations. These observations show that whilst early HIV-1 specific CD8 T cells can act against virus, rapid escape means that these T cell responses are unlikely to benefit the patient and may in part explain why current HIV-1 T cell vaccines may not be protective.

Korber, Bette Tina Marie [Los Alamos National Laboratory

2008-01-01T23:59:59.000Z

42

Twenty-first century vaccines  

Science Journals Connector (OSTI)

...not or are no longer dangerous. For example, many...to disruption of the health system in the former...vaccines are great but dangerous, and throughout the...perception that vaccines are dangerous and to be avoided...is no longer true. Health policy-makers should...

2011-01-01T23:59:59.000Z

43

A Job Seeker's Guide About this Guide  

E-Print Network [OSTI]

search. Write down all the jobs you applied to: include the title, company name, contact person & phoneA Job Seeker's Guide About this Guide This guide is designed to assist you in your job search. Included in this guide are many helpful tips that you can use throughout your job search process

Butler, Laurie J.

44

Toward Effective Vaccine Deployment: A Systematic Study  

Science Journals Connector (OSTI)

Vaccination is a commonly-used epidemic control strategy based on direct antiviral immunization and indirect reduction of virus transmissibility. There exist three factors related to the efficacy of vaccine deployment; they are: (1) vaccine coverage, ... Keywords: Age-specific compartmental model, Epidemic control, H1N1 influenza, Vaccine deployment strategy

Jiming Liu; Shang Xia

2011-10-01T23:59:59.000Z

45

Acquisition Guide  

Broader source: Energy.gov (indexed) [DOE]

.4 (February 20 10) .4 (February 20 10) Source Evaluation Board (SEB) Secretariat and Knowledge Manager Guiding Principles P Establishment of a SEB Secretariat and Knowledge Management position will improve both the Department's procurement system and its management of knowledge attained by the Department's procurement personnel. REFERENCES Department of Energy (DOE) report on "Report on Reengineering the Business Clearance Process" issued November 2007 National Academy of Public Administration report on "Managing at the Speed of Light - Improving Mission Support Performance" issued July 2009 Government Accountability Office (GAO) report on "Better Performance Measures and Management Needed to Address Delays in Awarding Contracts (GAO-06-722)" issued June

46

Vaccine refrigerator testing. Final report  

SciTech Connect (OSTI)

For the Central American Health Clinic Project initiated in 1986, Sandia National Laboratories and the Florida Solar Energy Center recognized the need for a test and evaluation program for vaccine refrigeration systems. At the Florida Solar Energy Center, side-by-side testing of three photovoltaic powered vaccine refrigerators began in 1987. The testing was expanded in 1988 to include a kerosene absorption refrigerator. This report presents observations, conclusions, and recommendations derived from testing the four vaccine refrigeration systems. Information is presented pertaining to the refrigerators, photovoltaic arrays, battery subsystems, charge controllers, and user requirements. This report should be of interest to designers, manufacturers, installers, and users of photovoltaic-powered vaccine refrigeration systems and components.

Ventre, G.G. [Univ. of Central Florida, Orlando, FL (United States); Kilfoyle, D.; Marion, B. [Florida Solar Energy Center, Cape Canaveral, FL (United States)

1990-06-01T23:59:59.000Z

47

Toward Design of a Universal Flu Vaccine  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Toward Design of a Universal Flu Vaccine Print Toward Design of a Universal Flu Vaccine Print Worldwide, influenza causes substantial deaths and yearly economic burdens, but the highly changeable nature of the flu virus complicates the production of an effective vaccine. The Centers for Disease Control and Prevention (CDC) estimates that the effectiveness of this year's flu vaccine is about 62%. For comparison, this number for childhood vaccines is routinely well over 90%. One factor in determining the vaccine's effectiveness is how closely related the viruses used in the vaccine are to the viruses circulating that year. An international team of researchers, working at synchrotron facilities including the ALS, has solved the crystal structures of antibodies that protect against broad classes of influenza strains. Greater understanding of these antibody structures may aid in the eventual development of a universal vaccine, protecting against all types of influenza viruses and thus eliminating the guesswork that currently limits vaccine effectiveness.

48

Acquisition Guide  

Broader source: Energy.gov (indexed) [DOE]

Chapter 71.1 (June 2010) Chapter 71.1 (June 2010) 1 HEADQUARTERS BUSINESS CLEARANCE PROCESS Overview This guide chapter provides guidance regarding the policies and procedures governing the Headquarters Business Clearance Review (BCR) process, the process by which certain procurement actions (solicitations, contracts, major contract changes, etc.) are reviewed and approved by the DOE Senior Procurement Executive (SPE) as a condition precedent to executing them. This section does not apply to the National Nuclear Security Administration (NNSA). Separate NNSA coverage is in BOP-003 and BOP-304. Background A. The Flow of Procurement Authority within the Department of Energy (DOE) The Secretary of Energy designated the Director, Office of Procurement and Assistance

49

Acquisition Guide  

Broader source: Energy.gov (indexed) [DOE]

3.2 (November 2009) 3.2 (November 2009) PURCHASE ORDERS GUIDING PRINCIPLES J Purchase Orders should normally be issued on a fixed-price basis. J Modifications of Purchase Orders may be used for unpriced orders and for administrative matters on priced orders. J Purchase orders cannot exceed the simplified acquisition threshold. This section discusses the Department of Energy's (DOE) use of purchase orders as described in Federal Acquisition Regulation (FAR) 13.302 and the Department of Energy's Acquisition Regulation (DEAR) Section 91 3.304. Only contracting officers acting within the scope of their authority are empowered to execute purchase orders on behalf of DOE. Authority A. Federal Acquisition Regulation (FAR) Subpart 13.302. B. DEAR 913.307 Background When shouldpurchase orders be used? Due to the administrative cost of preparing and handling

50

Engineered microneedles for transcutaneous vaccine delivery  

E-Print Network [OSTI]

Immunization is a powerful approach for the prevention and control of infectious disease, however despite the successes of modem vaccine development, there remain several notable obstacles for the advancement of vaccine-mediated ...

DeMuth, Peter C. (Peter Charles)

2013-01-01T23:59:59.000Z

51

VISION 2008 User's Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

VISION 2008 User's Guide VISION 2008 User's Guide ANL-08/34 Energy Systems Division VISION 2008 User's Guide ANL-08/34 User's Guide by J. Ward Vehicle Technologies Program, U.S. Department of Energy, Energy Efficiency and Renewable Energy VISION model by A. Vyas and M. Singh Transportation Technology R&D Center, Argonne National Laboratory October 2008 VISION 2008 User's Guide October 2008 i Table of Contents Copyright Notification .............................................................................................................................. ii List of Abbreviations ................................................................................................................................ iii

52

Baseline Cellular HIV DNA Load Predicts HIV DNA Decline and Residual HIV Plasma Levels during Effective Antiretroviral Therapy  

Science Journals Connector (OSTI)

...significant predictive power, but published data on its correlation...correlated with HIV DNA load decrease until...cellular HIV DNA load predicts HIV DNA...significant predictive power, but published data on its correlation...correlated with HIV DNA load decrease until...

Saverio Giuseppe Parisi; Samantha Andreis; Carlo Mengoli; Renzo Scaggiante; Roberto Ferretto; Vinicio Manfrin; Mario Cruciani; Mario Giobbia; Caterina Boldrin; Monica Basso; Massimo Andreoni; Giorgio Palù; Loredana Sarmati

2011-11-30T23:59:59.000Z

53

ADVERTISING GUIDE 2014 Advertising Guide, 20141  

E-Print Network [OSTI]

ADVERTISING GUIDE 2014 #12;Advertising Guide, 20141 Dear Geo Outlook Advertiser: We care about youth anniversary, we are dropping advertising prices back to the 2010-2012 rates. Commit by January 13 and the potential to add embedded QR codes inside your ads. Enclosed is information about advertising opportunities

54

HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission  

Science Journals Connector (OSTI)

...1 cloned directly from uncultured human brain tissue: identification of replication-competent...Dangond, MF McLane, M Essex, and JD Brain. 2007. Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor...

Ruizhong Shen; Milan Raska; Diane Bimczok; Jan Novak; Phillip D. Smith

2014-10-01T23:59:59.000Z

55

HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission  

Science Journals Connector (OSTI)

...HIV-1 after heterosexual transmission. Science 303 :2019-2022. doi: 10.1126/science.1093137 . 9. Wei, X , JM Decker, S Wang...immunity in the acquired immune response. Science 272 :50-53. doi: 10.1126/science...

Ruizhong Shen; Milan Raska; Diane Bimczok; Jan Novak; Phillip D. Smith

2014-10-01T23:59:59.000Z

56

Dengue vaccination may be cost effective in Brazil  

Science Journals Connector (OSTI)

Even when considering the relatively low efficacy of dengue vaccine shown in recent phase 2b trials, age-targeted vaccination may still be cost effective in Brazil provided the total vaccination cost is sufficien...

2013-07-01T23:59:59.000Z

57

Developing a DNA vaccine to protect against brucellosis  

E-Print Network [OSTI]

Brucella are Gram-negative intracellular pathogenic bacteria, which represent a threat to human and animal health. Live vaccine strains are available to protect some animal species but no vaccines exist for human use. A DNA vaccine could potentially...

Owen, David Matthew

2013-02-22T23:59:59.000Z

58

Exploiting lymphatic transport and complement activation in nanoparticle vaccines  

E-Print Network [OSTI]

Exploiting lymphatic transport and complement activation in nanoparticle vaccines Sai T Reddy1 in vaccine development. Here we investigate whether nanoparticles can be used as a vaccine platform complement activation. After intradermal injection, interstitial flow transported ultra-small nanoparticles

Floreano, Dario

59

HQ Leave Guide  

Broader source: Energy.gov (indexed) [DOE]

Leave Guide Leave Guide Purpose of this Guide The purpose of this guide is to provide you, as a Headquarters employee, advice and guidance concerning issues related to hours of duty, time & attendance, and matters related to taking time off (e.g., annual and sick leave). However, this guide can not provide all encompassing guidance for all situations. In many cases, the answer is subject to office policy and/or supervisory judgment. For these reasons, any questions about how matters in this guide apply to you should first be discussed with your supervisor. If your supervisor is unable to answer your specific question or issue, you or your supervisor should contact the Headquarters Employee/Labor Relations Services Team on (202) 586-8731. Who is Covered by this Guide

60

Toward Design of a Universal Flu Vaccine  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Toward Design of a Universal Flu Toward Design of a Universal Flu Vaccine Toward Design of a Universal Flu Vaccine Print Wednesday, 30 January 2013 00:00 Worldwide, influenza causes substantial deaths and yearly economic burdens, but the highly changeable nature of the flu virus complicates the production of an effective vaccine. The Centers for Disease Control and Prevention (CDC) estimates that the effectiveness of this year's flu vaccine is about 62%. For comparison, this number for childhood vaccines is routinely well over 90%. One factor in determining the vaccine's effectiveness is how closely related the viruses used in the vaccine are to the viruses circulating that year. An international team of researchers, working at synchrotron facilities including the ALS, has solved the crystal structures of antibodies that protect against broad classes of influenza strains. Greater understanding of these antibody structures may aid in the eventual development of a universal vaccine, protecting against all types of influenza viruses and thus eliminating the guesswork that currently limits vaccine effectiveness.

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Development of polymeric nanoparticle vaccines for immunostimulation  

E-Print Network [OSTI]

Vaccines have revolutionized medicine by increasing the life expectancy of children and substantially decreasing the morbidity of multiple infectious diseases worldwide. Over several decades, we have acquired significant ...

Basto, Pamela A. (Pamela Antonia)

2013-01-01T23:59:59.000Z

62

Alternative Financing - New Acquisition Guide Subchapter | Department...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Alternative Financing - New Acquisition Guide Subchapter Alternative Financing - New Acquisition Guide Subchapter policy flash Alternative Financing - New Acquisition Guide...

63

Kuda Training Guide_053013 | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Kuda Training Guide053013 Kuda Training Guide053013 Kuda TrainingGuide053013.pdf More Documents & Publications NTERTraining Guides FY13 Budget Resources Energy Walkabout...

64

Current Status of Vaccines for Schistosomiasis  

Science Journals Connector (OSTI)

...McManus. 2004. The cytoskeleton and motor proteins of human schistosomes and their...Holmgren. 2004. Current status and future prospects for a vaccine against schistosomiasis...Hookworm vaccines-past, present and future. Lancet Infect. Dis. 6: 733-741...

Donald P. McManus; Alex Loukas

2008-01-01T23:59:59.000Z

65

Congo polio strain can resist vaccine  

Science Journals Connector (OSTI)

... The cause of an unusually severe outbreak of poliomyelitis that hit Congo in 2010 has been identified: a strain of poliovirus that sometimes resists the immune ... vaccine, which provides the strongest immunity, are  protected against the strain. Its spread in Congo was stopped by orally re-vaccinating the entire population of the surrounding areas. ...

Ed Yong

2014-08-20T23:59:59.000Z

66

Advanced Energy Guides  

Broader source: Energy.gov (indexed) [DOE]

Energy Guides Energy Guides Shanti Pless National Renewable Energy Laboratory shanti.pless@nrel.gov 303-384-6365 April 4 2013 2 | Building Technologies Office eere.energy.gov Advanced Energy Design Guides Provide prescriptive energy savings guidance and recommendations by building type and geographic location: * Design packages and strategies to help owners and designers achieve 50% site energy savings over Standard 90.1 * Two series: - 30% savings over 90.1-1999

67

Advanced Energy Guides  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Energy Guides Energy Guides Shanti Pless National Renewable Energy Laboratory shanti.pless@nrel.gov 303-384-6365 April 4 2013 2 | Building Technologies Office eere.energy.gov Advanced Energy Design Guides Provide prescriptive energy savings guidance and recommendations by building type and geographic location: * Design packages and strategies to help owners and designers achieve 50% site energy savings over Standard 90.1 * Two series: - 30% savings over 90.1-1999

68

Precision guided antiaircraft munition  

DOE Patents [OSTI]

A small diameter, 20 mm to 50 mm, guided projectile is used in antiaircraft defense. A pulsing laser designator illuminates the target aircraft. Energy reflected from the aircraft is received by the guided projectile. The guided projectile is fired from a standard weapon but the spining caused by the riflings are removed before active tracking and guidance occurs. The received energy is focused by immersion optics onto a bridge cell. AC coupling and gating removes background and allows steering signals to move extended vanes by means of piezoelectric actuators in the rear of the guided projectile.

Hirschfeld, Tomas B. (Livermore, CA)

1987-01-01T23:59:59.000Z

69

Change Control Management Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Guide provides a suggested approach and uniform guidance for managing project and contract changes through applying the requirements of DOE O 413.3B. No cancellation.

2011-07-29T23:59:59.000Z

70

Benchmarking Help Center Guide  

Broader source: Energy.gov [DOE]

Benchmarking Help Center Guide provides recommendations for establishing a benchmarking help center based on experiences and lessons learned in New York City and Seattle.

71

EERE Program Management Guide  

Office of Energy Efficiency and Renewable Energy (EERE)

Updated in December 2007, this guide is a comprehensive reference manual on EERE program management. The following documents are available as Adobe Acrobat PDFs.

72

Asset Protection Analysis Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Guide provides examples of the application of as set protection analysis to several common problems. Canceled by DOE N 251.80.

2008-08-21T23:59:59.000Z

73

FTCP Guiding Documents  

Broader source: Energy.gov [DOE]

Federal Technical Capability Program (FTCP) Guiding Documents includes Key FTCP Directives, Qualification Standards, Functional Area Qualification Standard (FAQS) Qualification Cards, and Technical Qualification Program (TQP) Accreditation.

74

Effective epidemic control via strategic vaccine deployment: a systematic approach  

Science Journals Connector (OSTI)

Vaccination is an effective way to control infectious disease spreading and epidemic by adjusting the composite structure of susceptible, infectious and vaccinated populations. There are three factors related to vaccine deployment arrangements; they ... Keywords: disease infection, epidemic spreading dynamics, vaccine deployment

Jiming Liu; Shang Xia

2010-11-01T23:59:59.000Z

75

Participant Guide Cover Sheet  

E-Print Network [OSTI]

Proposal Management ­ State Transition (diagram) 4 Page 2 #12;eRPM Workflow eRPM system workflow starts Management - State Transitions Page 4 #12;Proposal Management Reviewer Participant Guide Last updated: 03Proposal Management Reviewer Participant Guide Cover Sheet Last updated: 03/20/09 1 of 1 http

Shyy, Wei

76

Video Center Administrator Guide  

E-Print Network [OSTI]

LifeSize® Video Center Administrator Guide March 2011 LifeSize Video Center 2200 #12;LifeSize Video Center Adminstrator Guide 2 Administering LifeSize Video Center LifeSize Video Center is a network server that stores and streams video sent by LifeSize video communications systems enabled for recording. It can also

Eisen, Michael

77

E-Print Network 3.0 - abortus vaccine strain Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

BCG Vaccination* About the BCG Vaccine BCG vaccine... is used for infants and small children in countries where TB is common. BCG ... Source: Virginia Tech, Virginia...

78

E-Print Network 3.0 - aids vaccines Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Harvard University Collection: Biology and Medicine 69 Vaccine 21 (2003) 28622870 Optimising vaccination strategies in equine influenza Summary: -l vaccines. J AIDS...

79

E-Print Network 3.0 - annual influenza vaccination Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Collection: Environmental Sciences and Ecology 46 Vaccine 21 (2003) 28622870 Optimising vaccination strategies in equine influenza Summary: -unit vaccines. The datasheets...

80

E-Print Network 3.0 - attenuated recombinant vaccine Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

include subunit vaccines (9), naked DNA vaccines (10,11), and attenuated mycobacte- ria, including... of New Tuberculosis Vaccines 12;12. Horwitz MA, Harth G, Dillon BJ,...

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

UESC Contracting Guide  

Broader source: Energy.gov (indexed) [DOE]

Contracting Guide Contracting Guide Karen Thomas National Renewable Energy Laboratory Purpose of the UESC Guide * The UESC Contracting Guide will include: - Information, sample documents, and templates needed to implement a task order under the GSA Areawide * FEMP is developing this initial guide for DOE sites * Subsequent books will be developed for other agencies as requested Objectives * Define UESC * Provide the steps involved in developing a UESC * Provide objectives, strategies, samples, and templates * Provide best practices and lessons learned Frequently Asked Questions * What is a UESC? * Is it legal? * What is the maximum allowable contract term? * Can renewables be included in a UESC? * Can rebates be accepted and used in the project? * What is a utility?

82

Ethics to guide environmental action  

Science Journals Connector (OSTI)

Ethics to guide environmental action ... "Environmental Ethics: Choices for Concerned Citizens" is advertised as "a timely guide" for persons wanting "a balanced yet ecologically conscious life-style." ...

1980-12-08T23:59:59.000Z

83

Permitting Guides | Department of Energy  

Energy Savers [EERE]

Permitting Guides Permitting Guides Standardized procedures for permitting hydrogen technologies and systems are not yet well established. As a first step, DOE sponsored...

84

Fighting HIV — Lessons from Brazil  

Science Journals Connector (OSTI)

...people by the end of 2005. Yet Brazil's persistent and aggressive efforts to prevent new HIV infections have probably played an equal or greater role in slowing the spread of the virus and containing the country's epidemic. At the beginning of the 1990s, the epidemics in Brazil and South Africa, both ranked... Dr. Susan Okie writes that Brazil's persistent and aggressive efforts to prevent new HIV infections have played a major role in slowing the spread of the virus and containing the country's epidemic.

Okie S.

2006-05-11T23:59:59.000Z

85

Operations & Maintenance Best Practices Guide: Chapter 3  

Broader source: Energy.gov [DOE]

Guide describes chapter 3 of the Operations & Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

86

Backfit Analysis Desktop Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

G 231.1-2 G 231.1-2 Approved: 08-20-03 OCCURRENCE REPORTING CAUSAL ANALYSIS GUIDE [This Guide describes suggested nonmandatory approaches for meeting requirements. Guides are not requirements documents and are not to be construed as requirements in any audit or appraisal for compliance with the parent Policy, Order, Notice, or Manual.] U.S. DEPARTMENT OF ENERGY Office of Environment, Safety and Health DISTRIBUTION: INITIATED BY: All Departmental Elements Office of Environment, Safety and Health DOE G 231.1-2 Page i 08-20-03 CONTENTS 1. PURPOSE ............................................................................................................................1 2. REFERENCES ....................................................................................................................1

87

HIV classification using coalescent theory  

SciTech Connect (OSTI)

Algorithms for subtype classification and breakpoint detection of HIV-I sequences are based on a classification system of HIV-l. Hence, their quality highly depend on this system. Due to the history of creation of the current HIV-I nomenclature, the current one contains inconsistencies like: The phylogenetic distance between the subtype B and D is remarkably small compared with other pairs of subtypes. In fact, it is more like the distance of a pair of subsubtypes Robertson et al. (2000); Subtypes E and I do not exist any more since they were discovered to be composed of recombinants Robertson et al. (2000); It is currently discussed whether -- instead of CRF02 being a recombinant of subtype A and G -- subtype G should be designated as a circulating recombination form (CRF) nd CRF02 as a subtype Abecasis et al. (2007); There are 8 complete and over 400 partial HIV genomes in the LANL-database which belong neither to a subtype nor to a CRF (denoted by U). Moreover, the current classification system is somehow arbitrary like all complex classification systems that were created manually. To this end, it is desirable to deduce the classification system of HIV systematically by an algorithm. Of course, this problem is not restricted to HIV, but applies to all fast mutating and recombining viruses. Our work addresses the simpler subproblem to score classifications of given input sequences of some virus species (classification denotes a partition of the input sequences in several subtypes and CRFs). To this end, we reconstruct ancestral recombination graphs (ARG) of the input sequences under restrictions determined by the given classification. These restritions are imposed in order to ensure that the reconstructed ARGs do not contradict the classification under consideration. Then, we find the ARG with maximal probability by means of Markov Chain Monte Carlo methods. The probability of the most probable ARG is interpreted as a score for the classification. To our knowledge, this particular problem was not addressed up to now. The software package Lamarc Kuhner et al. (2000) allows for sampling ARGs, but it assumes that recombination events only involve one breakpoint. However, in HIV recombinants usually have more than one breakpoint. Moreover, Lamarc does not perform an explicit breakpoint detection, but tries to find them by chance. Although this approach is suitable for most situations, it will not lead to satisfying results in case of highly recombining viruses with multiple breakpoints.

Zhang, Ming [Los Alamos National Laboratory; Letiner, Thomas K [Los Alamos National Laboratory; Korber, Bette T [Los Alamos National Laboratory

2008-01-01T23:59:59.000Z

88

Dilated Cardiomyopathy in Transgenic Mice Expressing HIV Tat  

Science Journals Connector (OSTI)

Mechanisms responsible for HIV cardiomyopathy are unknown, but may include direct effects of HIV proteins on the heart. Transgenic mice (TG) expressing HIV Tat protein targeted to the myocardium, +/? Tat TG, have...

Qiujuan Fang; Hong Kan; William Lewis; Fangping Chen…

2009-03-01T23:59:59.000Z

89

Tuberculosis vaccines: beyond bacille Calmette–Guérin  

Science Journals Connector (OSTI)

...Sander, C. R., Keating, S. M., Gilbert, S. C., Huygen, K., Fletcher...H., Clark, S. O., Hatch, G., Gilbert, S. C., Hill, A. V. S. 2005 Boosting...immunology Mycobacterium Infections immunology microbiology prevention & control Tuberculosis Vaccines...

2011-01-01T23:59:59.000Z

90

GUIDE FOR APPLICANTS COLLABORATIVE PROJECT  

E-Print Network [OSTI]

i GUIDE FOR APPLICANTS NMP COLLABORATIVE PROJECT FP7-NMP-2010-EU-USA Further copies of this Guide-site: http://cordis.europa.eu/ #12;NMP Guide for Applicants: Collaborative projects FP7-NMP-2010-EU-USA i-stage submission procedures. The main part of this Guide (sections 1 to 5) is common to all such calls. Information

Milano-Bicocca, Università

91

REScheck Software User's Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

REScheck Software REScheck Software User's Guide Building Energy Codes Program Table Of Contents Overview ................................................................................... 1 Tutorials ................................................................................. 2 Table Columns and Rows ............................................................. 3 Rows ...................................................................................... 3 Columns ................................................................................. 5 Project Information ..................................................................... 7 Location.................................................................................. 7 Project Type (2006 IECC) ..........................................................

92

DUF6 Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

DUF6 Guide DUF6 Guide Depleted UF6 Guide An introduction to uranium and its compounds, depleted uranium, and depleted uranium hexafluoride (depleted UF6). Uranium has unique properties that make it valuable as an energy source, yet potentially hazardous to human health and the environment. The Guide provides basic information about the properties of uranium compounds and the uranium enrichment process that produces depleted UF6. This information will help you understand the unique challenges involved in managing DOE's inventory of depleted UF6 in a safe and efficient manner. Overview Presentation DUF6 Health Risks Uranium and Its Compounds DUF6 Environmental Risks Depleted Uranium DUF6 Videos Uranium Hexafluoride Uranium Quick Facts DUF6 Production and Handling

93

Help Guide for Applicants  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Careers at Brookhaven 1 Careers at Brookhaven 1 October 2012 Careers at Brookhaven Help Guide for Applicants Table of Contents Brookhaven National Laboratory ................................................................................... 2 Careers at Brookhaven ..................................................................................................... 2 Careers Home Page ........................................................................................................... 3 Latest Job Postings ........................................................................................................... 5 Register to Login ............................................................................................................... 8

94

DOE Acquisition Guide ...  

Broader source: Energy.gov (indexed) [DOE]

Guide Chapter 16.2R1 (June 2014) Performance Evaluation and Measurement Plans for Cost-Reimbursement, Non- Management and Operating Contracts Reference: FAR 6, FAR 16, FAR 22, FAR...

95

admission guide International  

E-Print Network [OSTI]

2015/ 2016 admission guide International First-Year Students #12;2 3 WORLDWIDE RECOGNITION (2008 and Digital Media Critical Studies* Integrated Critical Practice* Production* German Studies Global Economics Networks Computer Science Computer Science: Computer Game Design Electrical Engineering Communications

California at Santa Cruz, University of

96

Cost Estimating Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides uniform guidance and best practices that describe the methods and procedures that could be used in all programs and projects at DOE for preparing cost estimates. No cancellations.

2011-05-09T23:59:59.000Z

97

Technology Readiness Assessment Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Guide assists individuals and teams involved in conducting Technology Readiness Assessments (TRAs) and developing Technology Maturation Plans (TMPs) for the DOE capital asset projects subject to DOE O 413.3B. Cancels DOE G 413.3-4.

2011-09-15T23:59:59.000Z

98

Brush Busters Mixing Guide  

E-Print Network [OSTI]

This easy-to-use guide gives mixing instructions for sprays to control huisache, mesquite, redberry cedar, saltcedar, tallowtree and yucca and to treat hardwood cut stumps. It can easily be attached to a sprayer if desired...

McGinty, Allan; Ueckert, Darrell

2004-02-05T23:59:59.000Z

99

Risk Management Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides non-mandatory risk management approaches for implementing the requirements of DOE O 413.3B, Program and Project Management for the Acquisition of Capital Assets. Cancels DOE G 413.3-7.

2011-01-18T23:59:59.000Z

100

Corrective Action Program Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide was developed to assist the Department of Energy (DOE) organizations and contractors in the development, implementation, and followup of corrective action programs utilizing the feedback and improvement core safety function within DOE's Integrated Safety Management System. This Guide outlines some of the basic principles, concepts, and lessons learned that DOE managers and contractors might consider when implementing corrective action programs based on their specific needs. Canceled by DOE G 414.1-2B. Does not cancel other directives.

2006-03-02T23:59:59.000Z

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Steam System Survey Guide  

Broader source: Energy.gov [DOE]

This guide provides technical information for steam system operational personnel and plant energy managers on some of the major opportunities available to improve the energy efficiency and productivity of industrial steam systems. The guide covers five main areas of investigation: (1) profiling a steam system, (2) identifying steam properties for the steam system, (3) improving boiler operations, (4) improving resource utilization in the steam system, and (5) investigating energy losses in the steam distribution system.

102

VOLTTRON: User Guide  

SciTech Connect (OSTI)

This document is a user guide for the deployment of the Transactional Network platform and agent/application development within the VOLTTRON. The intent of this user guide is to provide a description of the functionality of the Transactional Network Platform. This document describes how to deploy the platform, including installation, use, guidance, and limitations. It also describes how additional features can be added to enhance its current functionality.

Lutes, Robert G.; Katipamula, Srinivas; Akyol, Bora A.; Tenney, Nathan D.; Haack, Jereme N.; Monson, Kyle E.; Carpenter, Brandon J.

2014-04-24T23:59:59.000Z

103

Cognitive Neuropsychology of HIV-Associated Neurocognitive Disorders  

E-Print Network [OSTI]

of HIV-associated cognitive impairment. The ClinicalRourke, B. P. (2003). Cognitive complaints, depression,predicts subjective cognitive complaints in HIV infection.

Woods, Steven Paul; Moore, David J.; Weber, Erica; Grant, Igor

2009-01-01T23:59:59.000Z

104

A Citizen's Guide  

Broader source: Energy.gov (indexed) [DOE]

Citizen's Guide Citizen's Guide to the NEPA Having Your Voice Heard d e c e m b e r 2 0 0 7 c o u n c i l o n e n v i r o n m e n t a l q u a l i t y e x e c u t i v e o f f i c e o f t h e p r e s i d e n t A Citizen's Guide to the NEPA Having Your Voice Heard d e c e m b e r 2 0 0 7 c o u n c i l o n e n v i r o n m e n t a l q u a l i t y e x e c u t i v e o f f i c e o f t h e p r e s i d e n t This guide is based on research and consultations undertaken by the Council on Environmental Quality (CEQ) concerning the need for a Citizen's Guide to the National Environmental Policy Act (NEPA). Participants in the NEPA Regional Roundtables held in 2003-2004 clearly voiced the need for an guide that provides an explanation of NEPA, how it is implemented, and how people outside the Federal government - individual citizens, private sector applicants, members of organized groups, or representatives of Tribal, State,

105

HIV Co-receptor Usage in HIV-related Non-Hodgkin's Lymphoma  

E-Print Network [OSTI]

Access HIV Co-receptor usage in HIV-related non- hodgkin’stested for HIV co- receptor usage and SDF1 3’A polymorphism.CXCR4 and 8 (88.9%) with CCR5 usage, even though most of the

Reid, Erin; Morris, Sheldon R

2012-01-01T23:59:59.000Z

106

Methamphetamine and HIV-1 Tat Down Regulate ?-catenin Signaling: Implications for Methampetamine Abuse and HIV-1 Co-morbidity  

Science Journals Connector (OSTI)

Methamphetamine (Meth) abuse exacerbates HIV-1-associated neurocognitive disorders (HAND). The ... clear but likely involves cooperation between Meth and HIV-1 virotoxins, such as the transactivator of transcript...

Amit Sharma; Xiu-Ti Hu; T. Celeste Napier…

2011-12-01T23:59:59.000Z

107

Print the Fuel Economy Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Print the Fuel Economy Guide Print the Fuel Economy Guide 2014 Fuel Economy Guide 2014 Fuel Economy Guide Adobe Acrobat Icon MPG data updated December 19, 2013 The annual fuel cost estimates in the 2008-2014 electronic fuel economy guides are updated weekly to match EIA's current national average prices for gasoline and diesel fuel. Order a printed copy: Order Note that the published guides may not be as up-to-date at the downloadable version. View vehicles from 1984 to the present: Go to Find-a-Car Unlike the annual guides which cover only one model year, Find-a-Car provides the most up-to-date fuel economy information for vehicles from model year 1984 to the present, along with environmental and safety data. Find a Car Developer Tools 2013 Fuel Economy Guide 2013 Fuel Economy Guide Adobe Acrobat Icon

108

A Systematic Review of Psychological Functioning of Children Exposed to HIV: Using Evidence to Plan for Tomorrow’s HIV Needs  

Science Journals Connector (OSTI)

Prevention of mother to child transmission of HIV can virtually eliminate paediatric HIV infection. Studies are needed to understand child development outcomes for children exposed to HIV in utero but born HIV...

Lorraine Sherr; Natasha Croome; Katherine Parra Castaneda…

2014-11-01T23:59:59.000Z

109

NPS Quick Reference Guide | Open Energy Information  

Open Energy Info (EERE)

Reference GuideLegal Abstract NPS Quick Reference Guide, current through August 13, 2014. Published NA Year Signed or Took Effect 2014 Legal Citation NPS Quick Reference Guide...

110

Residential Retrofit Program Design Guide Overview Transcript...  

Broader source: Energy.gov (indexed) [DOE]

Residential Retrofit Program Design Guide Overview Transcript.doc Residential Retrofit Program Design Guide Overview Transcript.doc Residential Retrofit Program Design Guide...

111

OPAM Policy Acquisition Guides | Department of Energy  

Energy Savers [EERE]

Policy Acquisition Guides Acquisition Guides OPAM Policy Acquisition Guides More Documents & Publications Weighted Guidelines Weighted Guidelines Microsoft Word - Final MR AL.doc...

112

Structural health monitoring by ultrasonic guided waves  

E-Print Network [OSTI]

E. (2005) “Modeling guided wave propagation with applicationMultiple Guided Ultrasonic Wave Features,” ASME Journal ofto-spar joints using guided waves and macro fiber composite

Bartoli, Ivan

2007-01-01T23:59:59.000Z

113

Design and manufacture of low cost vaccine cooler  

E-Print Network [OSTI]

Vaccines are very sensitive to temperature, needing to be held between 2 and 80°C to maintain potency. In developing countries where electricity and fuel supplies are unreliable, many vaccines are ruined due to thermal ...

Panas, Cynthia Dawn Walker.

2007-01-01T23:59:59.000Z

114

The Ethics and Politics of Compulsory HPV Vaccination  

Science Journals Connector (OSTI)

...as safe as experts claim, and conviction that children receive more shots than are good for them. Laws making vaccination compulsory raise unique ethical and policy issues. High levels of herd immunity protect all members of the community, including those who cannot receive vaccines because of medical... On September 12, Michigan lawmakers became the first to propose that vaccination against human papillomavirus be compulsory for girls entering sixth grade. Dr. James Colgrove writes that laws making vaccination compulsory raise unique ethical and policy ...

Colgrove J.

2006-12-07T23:59:59.000Z

115

Relocation Guide, Human Resources  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Relocation Information Guide Relocation Information Guide The Human Resources Division is providing this Information Guide to you to help ease the transition of relocating to Long Island. Relocating to a new place can be an exciting as well as stressful time. We have compiled information that can be very helpful with the many issues you may face. You may also seek assistance from the recruiter you work with in Human Resources. Service Disclaimer - This web page contains links to other Internet sites. These links are not endorsements of any products or services and no information in such site has been endorsed or approved by Brookhaven National Laboratory or the Human Resources Division. Here are some of the issues: Cost of living Buying or renting a home Schools in the area

116

Unveiling the Implementation Guide  

Broader source: Energy.gov (indexed) [DOE]

Oak Ridge National Laboratory www.ornl.gov Oak Ridge National Laboratory www.ornl.gov Unveiling the Implementation Guide October 11, 2011 Michaela Martin Program Manager Residential, Commercial, and Industrial Energy Efficiency Oak Ridge National Laboratory 2 | Oak Ridge National Laboratory www.ornl.gov Guiding Principles for Successfully Implementing Industrial Energy Assessment Recommendations * New resource for industry * Identifies key principles and actions that lead to successful implementation of energy assessment recommendations * Connects readers with a variety of trusted resources * Simple tools for supporting energy management programs and continuous energy performance improvement efforts * Available in hard copy and on the web Implementation Guide Overview 3 | Oak Ridge National Laboratory www.ornl.gov

117

E-Print Network 3.0 - anti hiv-1 activity Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

to Prevent HIV-1 Infection The rgp120 HIV... virus type 1 (HIV-1) infection. ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

118

Mechanisms of HIV-associated neurotoxicity: Tat-induced synapse loss and recovery.  

E-Print Network [OSTI]

??HIV infection is a worldwide pandemic. A debilitating neurological consequence of HIV infection is progressive cognitive decline, known as HIV-associated neurocognitive disorders (HAND). HAND afflicts… (more)

Brunner, Angela Haijung

2013-01-01T23:59:59.000Z

119

Imitation dynamics of vaccination behaviour on social networks  

Science Journals Connector (OSTI)

...particular the SIR model, which tracks populations...or epidemic. Such models have been used...of vaccines or to predict whether a vaccination...24,25]. Our model captures the strategic...such as influenza. Flu vaccines are typically...prior to a predicted outbreak and are effective...

2011-01-01T23:59:59.000Z

120

Fuel Guide Economy  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

1 1 MODEL YEAR 2000 FUEL ECONOMY LEADERS IN POPULAR VEHICLE CLASSES Listed below are the vehicles with the highest fuel economy for the most popular classes, including both automatic and manual transmissions and gasoline and diesel vehicles. Please be aware that many of these vehicles come in a range of engine sizes and trim lines, resulting in different fuel economy values. Check the fuel economy guide or the fuel economy sticker on new vehicles to find the values for a particular version of a vehicle. CONTENTS MODEL YEAR 2000 FUEL ECONOMY LEADERS ................. 1 HOW TO USE THIS GUIDE ..................................................... 2 FUEL ECONOMY AND YOUR ANNUAL FUEL COSTS .......... 3 WHY FUEL ECONOMY IS IMPORTANT .................................

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

EIA Writing Style Guide  

Gasoline and Diesel Fuel Update (EIA)

EIA Writing Style Guide EIA Writing Style Guide U.S. Energy Information Administration Office of Communications This publication is available on the EIA employee intranet and at: www.eia.gov/eiawritingstyleguide.pdf U.S. government publications are not subject to copyright protection, but you should acknowledge EIA as the source if you use or reproduce this content. November 2012 Contents Introduction .................................................................................................................................................. 1 Quick Tips-Style, Writing, and Grammar Tips ............................................................................................ 5 Chapter 1. Editorial Voice and Words and Phrases To Avoid ....................................................................... 7

122

Quality Assurance REFERENCE GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Quality Assurance Quality Assurance Qualification Standard DOE-STD-1150-2002 July 2012 Reference Guide The Functional Area Qualification Standard References Guides are developed to assist operators, maintenance personnel, and the technical staff in the acquisition of technical competence and qualification within the Technical Qualification Program. Please direct your questions or comments related to this document to the Office of Leadership and Career Management, Technical Qualification Program (TQP) Manager, Albuquerque Complex. This page is intentionally blank. Table of Contents i FIGURES ....................................................................................................................................... ii TABLES ........................................................................................................................................ iii

123

Manifold tool guide  

DOE Patents [OSTI]

A tool guide is described that makes possible the insertion of cleaning and/or inspection tools into a manifold pipe that will dislocate and extract the accumulated sediment in such manifold pipes. The tool guide basically comprises a right angled tube (or other angled tube as required) which can be inserted in a large tube and locked into a radially extending cross pipe by adjustable spacer rods and a spring-loaded cone, whereby appropriate cleaning tools can be inserted into the cross pipe for cleaning, inspection, etc. 3 figs.

Djordjevic, A.

1983-12-27T23:59:59.000Z

124

Manifold tool guide  

DOE Patents [OSTI]

A tool guide that makes possible the insertion of cleaning and/or inspection tools into a manifold pipe that will dislocate and extract the accumulated sediment in such manifold pipes. The tool guide basically comprises a right angled tube (or other angled tube as required) which can be inserted in a large tube and locked into a radially extending cross pipe by adjustable spacer rods and a spring-loaded cone, whereby appropriate cleaning tools can be inserted into to cross pipe for cleaning, inspection, etc.

Djordjevic, A.

1982-07-08T23:59:59.000Z

125

Manifold tool guide  

DOE Patents [OSTI]

A tool guide that makes possible the insertion of cleaning and/or inspection tools into a manifold pipe that will dislocate and extract the accumulated sediment in such manifold pipes. The tool guide basically comprises a right angled tube (or other angled tube as required) which can be inserted in a large tube and locked into a radially extending cross pipe by adjustable spacer rods and a spring-loaded cone, whereby appropriate cleaning tools can be inserted into to cross pipe for cleaning, inspection, etc.

Djordjevic, Aleksandar (Thousand Oaks, CA)

1983-12-27T23:59:59.000Z

126

Seismic Safety Guide  

SciTech Connect (OSTI)

This guide provides managers with practical guidelines for administering a comprehensive earthquake safety program. The Guide is comprehensive with respect to earthquakes in that it covers the most important aspects of natural hazards, site planning, evaluation and rehabilitation of existing buildings, design of new facilities, operational safety, emergency planning, special considerations related to shielding blocks, non-structural elements, lifelines, fire protection and emergency facilities. Management of risk and liabilities is also covered. Nuclear facilities per se are not dealt with specifically. The principles covered also apply generally to nuclear facilities but the design and construction of such structures are subject to special regulations and legal controls.

Eagling, D.G. (ed.)

1983-09-01T23:59:59.000Z

127

Relationships between HIV spread and evolution examined  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3 » 3 » November » Relationships between HIV spread and evolution examined Relationships between HIV spread and evolution examined Thomas Leitner of LANL and collaborators are investigating the development of HIV from the point of contraction onwards. November 14, 2013 Scanning electron micrograph of HIV-1 budding (in green) from cultured lymphocytes. The image has been colored to highlight important features. Photo credit: C. Goldsmith, Centers for Disease Control and Prevention. Scanning electron micrograph of HIV-1 budding (in green) from cultured lymphocytes. The image has been colored to highlight important features. Photo credit: C. Goldsmith, Centers for Disease Control and Prevention. They are examining the relationships between the spread of the virus in a

128

Rainbow trapping of guided waves  

E-Print Network [OSTI]

Rainbow trapping of guided waves Javier Polanco and Rosa M.the propagation of a wave packet that is a superpositionof three s-polarized guided waves with different frequencies

Polanco, Javier; Fitzgerald, Rosa M; Leskova, Tamara A; Maradudin, Alexei A

2011-01-01T23:59:59.000Z

129

2009 Coal Age Buyers Guide  

SciTech Connect (OSTI)

The buyers guide lists more than 1200 companies mainly based in the USA, that provide equipment and services to US coal mines and coal preparation plants. The guide is subdivided by product categories.

NONE

2009-07-15T23:59:59.000Z

130

2008 Coal Age buyers guide  

SciTech Connect (OSTI)

The buyers guide lists more than 1200 companies mainly based in the USA, that provide equipment and services to US coal mines and coal preparation plants. The guide is subdivided by product categories.

NONE

2008-07-15T23:59:59.000Z

131

H2 Educate! Student Guide  

Fuel Cell Technologies Publication and Product Library (EERE)

H2 Educate! Teacher and Student Guides - These new guides were developed by the National Energy Education Development (NEED) Project's Teacher Advisory Board for the DOE Hydrogen Program. Sentech, Inc

132

H2 Educate! Teacher Guide  

Fuel Cell Technologies Publication and Product Library (EERE)

H2 Educate! Teacher and Student Guides - These new guides were developed by the National Energy Education Development (NEED) Project's Teacher Advisory Board for the DOE Hydrogen Program. Sentech, Inc

133

Ebola Vaccine — An Urgent International Priority  

Science Journals Connector (OSTI)

...unknown. Because of the small numbers of participants in these trials, they will provide data only on common adverse events. The cAd3 vaccine is being tested in both bivalent (ClinicalTrials.gov number, NCT02231866) and monovalent (NCT02240875) forms; the monovalent form is based on the Zaire strain of Ebola... With the Ebola epidemic in West Africa continuing to grow, the World Health Organization (WHO) convened an urgent meeting on September 29 and 30 to assess the efforts under way to evaluate and produce safe and effective Ebola vaccines as soon as possible....

2014-10-07T23:59:59.000Z

134

Selective Induction of Host Genes by MVA-B, a Candidate Vaccine against HIV/AIDS  

Science Journals Connector (OSTI)

...Bennink, V. M. Hirsch, S. Goldstein, W. R. Elkins, T. R. Fuerst, J. D. Lifson, M. Piatak, N. P. Restifo, W. Overwijk, R. Chamberlain, S. A. Rosenberg, and G. Sutter. 1996. Host range restricted, non-replicating vaccinia virus vectors...

Susana Guerra; José Manuel González; Núria Climent; Hugh Reyburn; Luis A. López-Fernández; José L. Nájera; Carmen E. Gómez; Felipe García; José M. Gatell; Teresa Gallart; Mariano Esteban

2010-06-09T23:59:59.000Z

135

Installation Guide 1. PREFACE .................................................................................................................................................... 3  

E-Print Network [OSTI]

AoC Installation Guide #12;Contents 1. PREFACE....................................................................................................................................................... 4 3.2 AOC............................................................................................................................................................. 4 3.3 AOC ADMIN

Natvig, Lasse

136

Business Model Guide Executive Summary  

Broader source: Energy.gov [DOE]

The Business Model Guide Executive Summary by the U.S. Department of Energy's Better Buildings Neighborhood Program.

137

Berea College Graphics Style Guide  

E-Print Network [OSTI]

, and its brand image. This Graphics Style Guide will help you with the technical aspects of representing

Baltisberger, Jay H.

138

HIV-1 Tat Is a Natively Unfolded Protein THE SOLUTION CONFORMATION AND DYNAMICS OF REDUCED HIV-1 Tat-(172)  

E-Print Network [OSTI]

HIV-1 Tat Is a Natively Unfolded Protein THE SOLUTION CONFORMATION AND DYNAMICS OF REDUCED HIV-1 (transactivation response element (TAR)) formed by the first 59 nucleotides of the HIV-1 RNA (4). Tat stimulates of HIV-dementia (15). A molecular understanding of Tat activity requires a determination of its structure

O'Neil, Joe

139

Operations & Maintenance Best Practices Guide: Chapter 9  

Broader source: Energy.gov [DOE]

Guide describes chapter 9 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

140

Operations & Maintenance Best Practices Guide: Front Matter  

Broader source: Energy.gov [DOE]

Guide describes the front matter of the Operations and Maintenance Best Practices: a Guide to Achieving Operational Efficiency.

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Operations & Maintenance Best Practices Guide: Appendix c  

Broader source: Energy.gov [DOE]

Guide describes Appendix C of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

142

Operations & Maintenance Best Practices Guide: Chapter 7  

Broader source: Energy.gov [DOE]

Guide describes chapter 7 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

143

Operations & Maintenance Best Practices Guide: Chapter 5  

Broader source: Energy.gov [DOE]

Guide describes chapter 5 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

144

Operations & Maintenance Best Practices Guide: Chapter 8  

Broader source: Energy.gov [DOE]

Guide describes chapter 8 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

145

Better Buildings Neighborhood Program Business Models Guide:...  

Broader source: Energy.gov (indexed) [DOE]

Guide: HVAC Contractor Business Model Better Buildings Neighborhood Program Business Models Guide: HVAC Contractor Business Model HVAC contractor business model...

146

Operations & Maintenance Best Practices Guide: Chapter 10  

Broader source: Energy.gov [DOE]

Guide describes chapter 10 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

147

Operations & Maintenance Best Practices Guide: Chapter 6  

Broader source: Energy.gov [DOE]

Guide describes chapter 6 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

148

Project Management Guide | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Management Structure projects Project Management Guide More Documents & Publications DOE Work Breakdown Structure Handbook PROJECT PLANNING TEMPLATE NDIAPMSCEVMSIntentGuide...

149

Better Buildings Neighborhood Program Business Models Guide:...  

Broader source: Energy.gov (indexed) [DOE]

Guide: Utility Program Administrator Market Better Buildings Neighborhood Program Business Models Guide: Utility Program Administrator Market Utility program administrator market...

150

Operations & Maintenance Best Practices Guide: Appendix a  

Broader source: Energy.gov [DOE]

Guide describes Appendix A of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

151

Guide to Workforce Planning  

Broader source: Energy.gov [DOE]

This guide provides supporting information that will help us align human resources processes to create short and long-term solutions for current and future human capital issues and provide a means of integrating and giving meaning to many areas of human resources initiatives that are at times over looked.

152

Transition Implementation Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide was prepared to aid in the development, planning, and implementation of requirements and activities during the transition phase at Department of Energy (DOE) facilities that have been declared or are forecast to become excess to any future mission requirements.

2001-04-24T23:59:59.000Z

153

International Student Guide Mathematics  

E-Print Network [OSTI]

International Student Guide Mathematics www.swansea.ac.uk/maths www.swansea.ac.uk/science/international #12;Reasons to study at Swansea University Mathematics at Swansea University Established in 1920, 36th and more Over 15,000 students / Over 2,000 International students Strongest in Wales for Mathematics

Harman, Neal.A.

154

Nonresident Alien Reference Guide  

E-Print Network [OSTI]

- 1 - Nonresident Alien Reference Guide #12;- 2 - Definition Nonresident Alien (NRA) is defined as any employee who is NOT a United States Citizen or a Permanent Resident (Resident Alien or Green Card status. These are NOT Immigration categories. United States Citizen Permanent Resident Alien Resident

Adali, Tulay

155

(Nonresident Alien) Reference Guide  

E-Print Network [OSTI]

- 1 - NRA (Nonresident Alien) Reference Guide #12;- 2 - UMBC'S OFFICES ASSISTING THE NONRESIDENT ALIEN (NRA) Office of International Education Administration Building 2nd floor Arlene Wergin Ext: 5 - Definition Nonresident Alien (NRA) is defined as any employee who is NOT a United States Citizen

Adali, Tulay

156

Information Security Guide  

E-Print Network [OSTI]

Information Security Guide For Government Executives Pauline Bowen Elizabeth Chew Joan Hash #12; Table of Contents Introduction 1 Why do I need to invest in information security? 2 Where do I need to focus my attention in accomplishing critical information security goals? 4 What are the key activities

157

Registration Guide Summer Sessions  

E-Print Network [OSTI]

Anchorage published in the Student Handbook, UAA Catalog and this Registration Guide. The Student Handbook affirmative action to achieve that end. The university does not discriminate in its educational and employ orientation, veteran status, physical or mental disability, marital status, pregnancy, or parenthood

Pantaleone, Jim

158

Registration Guide Classes start*  

E-Print Network [OSTI]

and regulations of the University of Alaska Anchorage published in the Student Handbook, UAA Catalog and this Registration Guide. The Student Handbook can be found at www to achieve that end. The university does not discriminate in its educational and employ- ment programs

Pantaleone, Jim

159

Mail Services User's Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides information on using Department of Energy (DOE) mail services in accordance with U.S. Postal Service, General Services Administration (GSA), and DOE regulations. Cancels DOE M 573.1-1. Canceled by DOE N 251.89.

2005-10-03T23:59:59.000Z

160

Quality Assurance Program Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides information on principles, requirements, and practices used to establish and implement an effective Quality Assurance Program. Cancels DOE G 414.1-2A, DOE G 414.1-3 and DOE G 414.4-5. Admin Chg 1, dated 9-27-11. Admin Chg 2, dated 5-8-13.

2011-08-16T23:59:59.000Z

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Quality Assurance Program Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides information on principles, requirements, and practices used to establish and implement an effective Quality Assurance Program. Cancels DOE G 414.1-2A, DOE G 414.1-3 and DOE G 414.1-5. Admin Chg 1, dated 9-27-11. Admin Chg 2, dated 5-8-13.

2011-08-16T23:59:59.000Z

162

International guide: blasthole drills  

SciTech Connect (OSTI)

This survey is a comprehensive quick reference guide for surface mine operators. It details rotary blasthole drill rigs that are available around the world. More than 60 drills, each with a pulldown of about 125 kN, are included in the survey.

Chadwick, J.R.

1982-01-01T23:59:59.000Z

163

Sensor Characteristics Reference Guide  

SciTech Connect (OSTI)

The Buildings Technologies Office (BTO), within the U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), is initiating a new program in Sensor and Controls. The vision of this program is: • Buildings operating automatically and continuously at peak energy efficiency over their lifetimes and interoperating effectively with the electric power grid. • Buildings that are self-configuring, self-commissioning, self-learning, self-diagnosing, self-healing, and self-transacting to enable continuous peak performance. • Lower overall building operating costs and higher asset valuation. The overarching goal is to capture 30% energy savings by enhanced management of energy consuming assets and systems through development of cost-effective sensors and controls. One step in achieving this vision is the publication of this Sensor Characteristics Reference Guide. The purpose of the guide is to inform building owners and operators of the current status, capabilities, and limitations of sensor technologies. It is hoped that this guide will aid in the design and procurement process and result in successful implementation of building sensor and control systems. DOE will also use this guide to identify research priorities, develop future specifications for potential market adoption, and provide market clarity through unbiased information

Cree, Johnathan V.; Dansu, A.; Fuhr, P.; Lanzisera, Steven M.; McIntyre, T.; Muehleisen, Ralph T.; Starke, M.; Banerjee, Pranab; Kuruganti, T.; Castello, C.

2013-04-01T23:59:59.000Z

164

Risk Management Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides a framework for identifying and managing key technical, schedule, and cost risks through applying the requirements of DOE O 413.3A, Program and Project Management for the Acquisition of Capital Assets, dated 7-28-06. Canceled by DOE G 413.3-7A, dated 1-12-11. Does not cancel other directives.

2008-09-16T23:59:59.000Z

165

Information Technology Project Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides Department of Energy recommended guidelines to ensure that the acquisition of information technology capital assets is performed in compliance with DOE O 413.3A, Program and Project Management for the Acquisition of Capital Assets, dated 7-28-06. Canceled by DOE N 251.105.

2008-09-12T23:59:59.000Z

166

GUIDE FOR APPLICANTS COLLABORATIVE PROJECT  

E-Print Network [OSTI]

i GUIDE FOR APPLICANTS HEALTH COLLABORATIVE PROJECT FP7-HEALTH-2010-single-stage Further copies the following web-site: http://cordis.europa.eu/ #12;Theme: HEALTH Guide for Applicants: Collaborative projects for Applicants for calls using single-stage submission procedures. The main part of this Guide (sections 1 to 5

Milano-Bicocca, Università

167

GUIDE FOR APPLICANTS COLLABORATIVE PROJECT  

E-Print Network [OSTI]

i GUIDE FOR APPLICANTS HEALTH COLLABORATIVE PROJECT Call identifier: FP7-HEALTH-2010-Alternative: Collaborative projects FP7-HEALTH-2010-Alternative-Testing i About this Guide This is version number 4 of the FP7 Guide for Applicants for calls using single-stage submission procedures. The main part

Milano-Bicocca, Università

168

GUIDE FOR APPLICANTS COLLABORATIVE PROJECT  

E-Print Network [OSTI]

i GUIDE FOR APPLICANTS NMP COLLABORATIVE PROJECT FP7-NMP-2010-EU-Mexico Further copies the following web-site: http://cordis.europa.eu/ #12;NMP Guide for Applicants: Collaborative projects FP7-NMP using single-stage submission procedures. The main part of this Guide (sections 1 to 5) is common to all

Milano-Bicocca, Università

169

HPV Vaccination Mandates — Lawmaking amid Political and Scientific Controversy  

Science Journals Connector (OSTI)

...Robust public health evidence supports the effectiveness of vaccination mandates in achieving high rates of vaccination coverage. However, proposals for coercive measures may trigger backlash — perhaps for reasons largely unrelated to the merits of the particular proposal. This danger underscores the... In 2006 and 2007, legislation to include the human papillomavirus (HPV) vaccine among the vaccines required for school entry was introduced in 24 states; only two bills were adopted. The factors that impeded the adoption of mandates included the newness of the vaccine, the sexually transmitted nature of HPV, the manufacturer's involvement in policymaking, and antivaccination activism.

Colgrove J.Abiola S.Mello M.M.

2010-08-19T23:59:59.000Z

170

Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases  

Science Journals Connector (OSTI)

...to the life expectancy of children who were born in the vaccine era. Yet vaccines today generate more controversy than praise, and they remain an invisible resource to the public, hanging in a precarious balance between success in the realm of public health and financial failure in the private sector... Vaccines topped the list of the most important public health achievements in the United States at the close of the 20th century and contributed decades to the life expectancy of children who were born in the vaccine era. Yet vaccines today generate more ...

Maldonado Y.

2007-10-25T23:59:59.000Z

171

Vaccinating High-Risk Children with the Intranasal Live-Attenuated Influenza Vaccine: the Quebec Experience  

Science Journals Connector (OSTI)

Summary Given the burden of illness associated with influenza, vaccination is recommended for individuals at high risk of complications. The live-attenuated influenza vaccine (LAIV) is administered by intranasal spray, thus directly stimulating mucosal immunity. In this review, we aimed to provide evidence for its efficacy and safety in different paediatric populations. We also share the Quebec experience of LAIV use through a publicly funded vaccination program for children with chronic, high-risk conditions. Results from randomized controlled trials in healthy children and in asthmatics have demonstrated superior efficacy of LAIV over the injectable vaccine (IIV). LAIV is well tolerated: its administration is associated with runny nose and nasal congestion, but not with asthma exacerbations and is well tolerated in children with cystic fibrosis, when compared to IIV. The vaccine is well accepted by children and parents and can easily be part of vaccination clinics in paediatric tertiary care centres targeting children with chronic, high-risk conditions, not leading to immunosuppression.

Caroline Quach

2014-01-01T23:59:59.000Z

172

Cancer vaccines: Trafficking of tumor-specific T cells to tumor after therapeutic vaccination  

Science Journals Connector (OSTI)

Abstract Cancer vaccines can induce robust activation of tumor-specific CD8+ T cells that can destroy tumors. Understanding the mechanism by which cancer vaccines work is essential in designing next-generation vaccines with more potent therapeutic activity. We recently reported that short peptides emulsified in poorly biodegradable, Incomplete Freund's Adjuvant (IFA) primed CD8+ T cells that did not localize to the tumor site but accumulated at the persisting, antigen-rich vaccination site. The vaccination site eventually became a T cell graveyard where T cells responded to chronically released gp100 peptide by releasing cytokines, including interferon-? (IFN-?), which in turn upregulated Fas ligand (FasL) on host cells, causing apoptosis of Fas+ T cells. T cells that escaped apoptosis rapidly became exhausted, memory formation was poor, and therapeutic impact was minimal. Replacing the non-biodegradable IFA-based formulation with water-based, short-lived formulation in the presence of immunostimulatory molecules allowed T cells to traffic to tumors, causing their regression. In this review, we discuss recent advances in immunotherapeutic approaches that could enhance vaccine-primed immune cells fitness and render the tumor microenvironment more accessible for immune cell infiltration.

Yared Hailemichael; Willem W. Overwijk

2014-01-01T23:59:59.000Z

173

tat Exon 1 Exhibits Functional Diversity during HIV-1 Subtype C Primary Infection  

Science Journals Connector (OSTI)

...immunodeficiency virus type 1 (HIV-1) Tat is a mediator of viral transcription...However, associations between HIV-1 Tat diversity and functional effects...study to genetically characterize HIV-1 tat during primary HIV-1C infection...

Raabya Rossenkhan; Iain J. MacLeod; Theresa K. Sebunya; Eduardo Castro-Nallar; Mary Fran McLane; Rosemary Musonda; Berhanu A. Gashe; Vlad Novitsky; M. Essex

2013-03-13T23:59:59.000Z

174

E-Print Network 3.0 - african hiv programme Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

3 Sexual prevention of HIV within the couple after prenatal HIV-testing in West Africa Summary: of sexual transmission of HIV occur within stable relationships in high HIV...

175

Veterinary and human vaccine evaluation methods  

Science Journals Connector (OSTI)

...tongue. Animals are observed for foot lesions. From these data...can improve the statistical power when sample size is small...2013 The economic impacts of foot and mouth disease-what are...S . 2009 Vaccination against foot-and-mouth disease virus...

2014-01-01T23:59:59.000Z

176

Vaccine approaches with Edinburgh Infectious Diseases  

E-Print Network [OSTI]

Vaccine approaches with Edinburgh Infectious Diseases Alexander Corbishley #12;The technology approaches to knowledge exchange · October 2013: three technology scouts seconded for 12 months, to identify Congress 2014 (Washington DC) · Local partnering meetings with SMEs · Discussions with Open Innovation

Maizels, Rick

177

Vaccines and future global health needs  

Science Journals Connector (OSTI)

...eradication. The new strategic plan calls for completion by 2013, but both pre-eradication...polio vaccine two weeks apart around the index case works well in re-infected countries...eradication. The new strategic plan calls for completion by 2013, but both pre-eradication...

2011-01-01T23:59:59.000Z

178

Subterranean well pipe guiding apparatus  

SciTech Connect (OSTI)

A pipe guiding apparatus is described for vertically aligning pipe section joints in a derrick having a worktable and an elevator for vertically suspending at least one pipe section above the worktable. The apparatus is comprised of a rotary axle for horizontal attachment in the derrick, a frame attached to the rotary axle, a power cylinder for rotating the rotary axle, a pair of guide jaws pivotally attached to the forward end of the frame, and a cylinder for moving the guide jaws between open and closed positions. The power cylinder for rotating the axle and the cylinder for moving the guide jaws between open and closed positions. The power cylinder for rotating the axle and the cylinder for moving the guide jaws are remotely operated so that the frame can be selectively moved to a position whereby the guide jaws are adjacent a vertically suspended pipe section and the guide jaws thereafter are closed on the pipe section. 6 claims.

Scaggs, O.C.

1981-06-23T23:59:59.000Z

179

Regulation of HIV-1 gene expression  

SciTech Connect (OSTI)

The quantity and quality of HIV-1 gene expression is temporally controlled by a cascade of sequential regulatory interactions. basal HIV-1 transcription is determined by interaction of cellular regulatory proteins with specific DNA target sequences within the HIV-1 long-terminal repeat. The most notable of these protein: DNA interactions involves NF-{aleph}B, a transcription factor that plays a pivotal role in the activation of genes important for cellular responses to infection and inflammation. A second level of control involves the virally encoded Tat trans-activator. Tat, in combination with as yet unidentified cellular proteins, activates HIV-1 gene expression through a specific interaction with the viral TAR RNA stem-loop target sequence. A final level of regulation is mediated by the viral Rev protein. Rev acts posttranscriptionally to induce the expression of HIV-1 structural proteins and thereby commits HIV-1 to the late, cytopathic phase of the viral replication cycle. Rev activity appears to require a critical, threshold level of Rev protein expression, thus preventing entry into this late phase in cells that are unable to support efficient HIV-1 gene expression. In total, this cascade of regulatory levels allow the HIV-1 provirus to respond appropriately to the intracellular milieu present in each infected cell. In activated cells, the combination of Tat and Rev can stimulate a very high level of viral gene expression and replication. In quiescent or resting cells, in contrast, these same regulatory proteins are predicted to maintain the HIV-1 provirus in a latent or nonproductive state.

Cullen, B.R. (Duke Univ., Durham, NC (United States))

1991-07-01T23:59:59.000Z

180

Guide to Chemistry Dept  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Guide to the Chemistry Building Guide to the Chemistry Building The main Chemistry building (Building 555) has been designed to make adequate facilities available for research and to provide an informal atmosphere for free exchange among Department members. There are public areas, shared laboratories, shared office space, and privately assigned places. A newcomer to the building should become familiar with locations of the key areas. Stairs and Elevators - Building 555 The central main staircase and a passenger elevator are for personnel traffic only. Each wing has a staircase. There is a rear staircase for traffic directly to service areas. The building has a freight elevator at the rear core. Flammable material, chemicals, solvents, gas cylinders, etc. can be transported in the freight elevator but not in the passenger elevator. Do not ride with gas cylinders or dewars charged with cryogens as the presence of these in a confined space introduces a suffocation hazard.

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Environmental Compliance Guide  

SciTech Connect (OSTI)

The Guide is intended to assist Department of Energy personnel by providing information on the NEPA process, the processes of other environmental statutes that bear on the NEPA process, the timing relationships between the NEPA process and these other processes, as well as timing relationships between the NEPA process and the development process for policies, programs, and projects. This information should be helpful not only in formulating environmental compliance plans but also in achieving compliance with NEPA and various other environmental statutes. The Guide is divided into three parts with related appendices: Part I provides guidance for developing environmental compliance plans for DOE actions; Part II is devoted to NEPA with detailed flowcharts depicting the compliance procedures required by CEQ regulations and Department of Energy NEPA Guidelines; and Part III contains a series of flowcharts for other Federal environmental requirements that may apply to DOE projects.

None

1981-02-01T23:59:59.000Z

182

Hydrogen Technologies Safety Guide  

SciTech Connect (OSTI)

The purpose of this guide is to provide basic background information on hydrogen technologies. It is intended to provide project developers, code officials, and other interested parties the background information to be able to put hydrogen safety in context. For example, code officials reviewing permit applications for hydrogen projects will get an understanding of the industrial history of hydrogen, basic safety concerns, and safety requirements.

Rivkin, C.; Burgess, R.; Buttner, W.

2015-01-01T23:59:59.000Z

183

Building Energy Code Resource Guide: Air Leakage Guide | Building Energy  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Air Leakage Guide Air Leakage Guide The U.S. Department of Energy (DOE) recognizes the enormous potential that exists for improving the energy efficiency, safety and comfort of homes. The 2012 International Energy Conservation Code (IECC) sets the bar for energy efficiency, and air sealing requirements are one of the key provisions. This guide is a resource for understanding the air leakage requirements in the 2012 IECC and suggestions on how these measures can be met. It also provides information from Building America's Air Sealing Guide, best Practices and case studies on homes that are currently meeting the provisions. The 2012 IECC and a few International Residential Code requirements are referenced throughout the guide. Publication Date: Friday, September 30, 2011 BECP_Buidling Energy Code Resource Guide Air Leakage

184

Cellular Cofactors for HIV-1 Transcription  

Science Journals Connector (OSTI)

Several host cell factors, the chromatin structure of the viral LTR promoter, and the RNA-binding Tat transactivator regulate the transcription of the integrated HIV-1 genome. Transcriptional latency of the pr...

Mauro Giacca

2014-09-01T23:59:59.000Z

185

Neurosyphilis in HIV-infected patients  

Science Journals Connector (OSTI)

To determine the prevalence and the clinical and serological findings of neurosyphilis in HIV-infected patients,Treponema pallidum hemagglutination (TPHA) tests, CD4+ lymphocyte counts and determination of rapid ...

J. Bordón; C. Martinez-Vázquez; M. Alvarez…

1995-10-01T23:59:59.000Z

186

How HIV Infects Cells | Advanced Photon Source  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Simulating Deep Earthquakes in the Laboratory Simulating Deep Earthquakes in the Laboratory A "Sponge" Path to Better Catalysts and Energy Materials Metal Model Mimics Metalloenzymes New Physics in a Copper-Iridium Compound A Key Target for Diabetes Drugs Science Highlights Archives: 2013 | 2012 | 2011 | 2010 2009 | 2008 | 2007 | 2006 2005 | 2004 | 2003 | 2002 2001 | 2000 | 1998 | Subscribe to APS Science Highlights rss feed How HIV Infects Cells September 26, 2013 Bookmark and Share The structure of the CCR5 cell surface receptor, which most strains of HIV use to enter human immune cells. This image shows the HIV drug maraviroc grabbing hold of CCR5 in an inactive conformation that prevents HIV from using the receptor to enter cells. (Image by Katya Kadyshevskaya, The Scripps Research Institute)

187

Natural Gas Study Guide - High School | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

High School Natural Gas Study Guide - High School Natural Gas Study Guide - High School Natural Gas Study Guide - High School More Documents & Publications Natural Gas Study Guide...

188

Residential Retrofit Design Guide Overview | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Residential Retrofit Design Guide Overview Residential Retrofit Design Guide Overview Residential Retrofit Design Guide Overview Webinar. Res Retro Design Guide Webinar 5-3-11...

189

Coal Study Guide - High School | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

High School Coal Study Guide - High School Coal Study Guide - High School More Documents & Publications Coal Study Guide - Middle School Coal Study Guide for Elementary School...

190

Coal Study Guide - Middle School | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Middle School Coal Study Guide - Middle School Coal Study Guide - Middle School More Documents & Publications Coal Study Guide for Elementary School Coal Study Guide - High School...

191

Epidemiological consequences of an ineffective Bordetella pertussis vaccine  

E-Print Network [OSTI]

The recent increase in Bordetella pertussis incidence (whooping cough) presents a challenge to global health. Recent studies have called into question the effectiveness of acellular B. pertussis vaccination in reducing transmission. Here we examine the epidemiological consequences of an ineffective B. pertussis vaccine. Using a dynamic transmission model, we find that: 1) an ineffective vaccine can account for the observed increase in B. pertussis incidence; 2) asymptomatic infections can bias surveillance and upset situational awareness of B. pertussis; and 3) vaccinating individuals in close contact with infants too young to receive vaccine (so called "cocooning" unvaccinated children) may be ineffective. Our results have important implications for B. pertussis vaccination policy and paint a complicated picture for achieving herd immunity and possible B. pertussis eradication.

Althouse, Benjamin M

2014-01-01T23:59:59.000Z

192

Building Technologies Office: Advanced Energy Retrofit Guides  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Energy Energy Retrofit Guides to someone by E-mail Share Building Technologies Office: Advanced Energy Retrofit Guides on Facebook Tweet about Building Technologies Office: Advanced Energy Retrofit Guides on Twitter Bookmark Building Technologies Office: Advanced Energy Retrofit Guides on Google Bookmark Building Technologies Office: Advanced Energy Retrofit Guides on Delicious Rank Building Technologies Office: Advanced Energy Retrofit Guides on Digg Find More places to share Building Technologies Office: Advanced Energy Retrofit Guides on AddThis.com... About Take Action to Save Energy Activities 179d Tax Calculator Advanced Energy Design Guides Advanced Energy Retrofit Guides Building Energy Data Exchange Specification Buildings Performance Database Data Centers Energy Asset Score

193

Autodesk MapGuide Working with Resources  

E-Print Network [OSTI]

Autodesk MapGuide® Enterprise Working with Resources Autodesk MapGuide® Enterprise software has and the resource service API in Autodesk MapGuide Enterprise. The information in this paper is applicable to both the MapGuide Open Source and Autodesk MapGuide Enterprise versions of the platform. #12;AUTODESK MAPGUIDE

Ahmad, Sajjad

194

Residential Retrofit Program Design Guide  

Broader source: Energy.gov [DOE]

This Residential Retrofit Program Design Guide focuses on the key elements and design characteristics of building and maintaining a successful residential retrofit program.

195

FAQS Reference Guide- Aviation Manager  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the January 2010 edition of DOE-STD-1164-2003 Chg 1, Aviation Safety Officer Functional Area Qualification Standard.

196

FAQS Reference Guide – Criticality Safety  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the April 2009 edition of DOE-STD-1173-2009, Criticality Safety Functional Area Qualification Standard.

197

Acquisition Guide | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Samples - forms and other useful documentation. The Guide is intended to serve as a primer on various acquisition issues, and may not present lengthy discussion on every...

198

FAQS Reference Guide- Chemical Processing  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the February 2010 edition of DOE-STD-1176-2010, Chemical Processing Functional Area Qualification Standard.

199

FAQS Reference Guide – Emergency Management  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the January 2004 edition of DOE-STD-1177-2004, Emergency Management Functional Area Qualification Standard.

200

DOE eGuide Lite  

Broader source: Energy.gov [DOE]

The DOE eGuide Lite teaches organizations the basics of better energy management. This includes understanding what kinds of energy they use, how they use it and how much of it they use. The eGuide Lite will also help organizations improve their understanding of energy costs and increase their awareness of options to reduce energy consumption. The eGuide Lite is based on the "learn-by-doing" model, and organizations who use this module will be guided through the steps of implementing basic energy management. The goal is that organizations who use this module will identify, plan and initiate sustainable energy improvements on an ongoing basis.

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Thermodynamics Student Guide (6 Activities)  

Broader source: Energy.gov (indexed) [DOE]

to you by the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy. THfRMODYNAMICS Student Guide TABL Of CONTNTS Introduction......

202

FAQS Reference Guide – Industrial Hygiene  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the November 2007 edition of DOE-STD-1138-2007, Industrial Hygiene Functional Area Qualification Standard.

203

FAQS Reference Guide – Facility Representative  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the October 2010 edition of DOE-STD-1151-2010, Facility Representative Functional Area Qualification Standard.

204

Management and Independent Assessments Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The Guide reflects updated standards for assessment practices, international standards, and changes in DOE expectations related to quality assurance (QA). Cancels DOE G 414.1-1B.

2014-03-27T23:59:59.000Z

205

Development of a receptor model for efficient in silico screening of HIV-1 integrase inhibitors  

Science Journals Connector (OSTI)

Abstract Integrase (IN) is a key viral enzyme for the replication of the type-1 human immunodeficiency virus (HIV-1), and as such constitutes a relevant therapeutic target for the development of anti-HIV agents. However, the lack of crystallographic data of HIV IN complexed with the corresponding viral DNA has historically hindered the application of modern structure-based drug design techniques to the discovery of new potent IN inhibitors (INIs). Consequently, the development and validation of reliable HIV IN structural models that may be useful for the screening of large databases of chemical compounds is of particular interest. In this study, four HIV-1 IN homology models were evaluated respect to their capability to predict the inhibition potency of a training set comprising 36 previously reported \\{INIs\\} with IC50 values in the low nanomolar to the high micromolar range. Also, 9 inactive structurally related compounds were included in this training set. In addition, a crystallographic structure of the IN-DNA complex corresponding to the prototype foamy virus (PFV) was also evaluated as structural model for the screening of inhibitors. The applicability of high throughput screening techniques, such as blind and ligand-guided exhaustive rigid docking was assessed. The receptor models were also refined by molecular dynamics and clustering techniques to assess protein sidechain flexibility and solvent effect on inhibitor binding. Among the studied models, we conclude that the one derived from the X-ray structure of the PFV integrase exhibited the best performance to rank the potencies of the compounds in the training set, with the predictive power being further improved by explicitly modeling five water molecules within the catalytic side of IN. Also, accounting for protein sidechain flexibility enhanced the prediction of inhibition potencies among the studied compounds. Finally, an interaction fingerprint pattern was established for the fast identification of potent IN inhibitors. In conclusion, we report an exhaustively validated receptor model if IN that is useful for the efficient screening of large chemical compounds databases in the search of potent HIV-1 IN inhibitors.

Mario A. Quevedo; Sergio R. Ribone; Margarita C. Briñón; Wim Dehaen

2014-01-01T23:59:59.000Z

206

Guide to Good Horsekeeping  

E-Print Network [OSTI]

Horsekeeping A Guide to Good Benefits for your horses, your land, and you EM-107 2010 Author: Emily Moench Texas AgriLife Extension Assistant January 14, 2008 Reviewers: Dr. Joe Paschal District 11 AgriLife Extension Animal Science... by the implementation of the TMDL and can be a combination of landown- ers, business owners, and government representatives. The decisions made in your watershed have a direct impact on you and your business and there are many reasons for you to get involved...

Moench, Emily K.

207

RACORO Data Guide  

SciTech Connect (OSTI)

This document provides an overview to the five-month RACORO Campaign. There are many details in such an extensive program that this document cannot capture; therefore, it should be thought of as a guide for acquainting yourself with the program and you are encouraged to contact the members involved. In particular, users of the data are strongly urged to contact instrument principal investigators (PIs) about use of the data. Further, it is highly recommended that studies using the data be done in collaboration with the instrument PIs, since they are in the best position to provide insights and or caveats associated with the data that should be considered.

Vogelmann, A

2010-10-12T23:59:59.000Z

208

Transmission Dynamics of an Influenza Model with Vaccination and ...  

E-Print Network [OSTI]

Jun 30, 2009 ... promised if drug-resistant strains arise. In this paper, we develop a mathematical model to explore the impact of vaccination and antiviral ...

2010-01-15T23:59:59.000Z

209

MapGuide Open Source 2.0 Developer's Guide  

E-Print Network [OSTI]

MapGuide Open Source 2.0 Developer's Guide January 2008 #12;Copyright© 2006­2008 Autodesk, Inc license shall not apply to, any of Autodesk's or a third party's trademarks used in this document. AUTODESK, INC., MAKES NO WARRANTY, EITHER EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO ANY IMPLIED

Ahmad, Sajjad

210

AOC-by-Self-discovery Modeling and Simulation for HIV  

Science Journals Connector (OSTI)

Among HIV, immune cell and drug, exhibit interactions that are usually not well understood and as a result, cannot be accurately modeled. In this paper, Modeling by AOC is to understand the dynamics of HIV infect...

Chunxiao Zhao; Ning Zhong; Ying Hao

2007-01-01T23:59:59.000Z

211

Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins  

DOE Patents [OSTI]

The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Korber, Bette T. (Los Alamos, NM); Perkins, Simon (Los Alamos, NM); Bhattacharya, Tanmoy (Los Alamos, NM); Fischer, William M. (Los Alamos, NM); Theiler, James (Los Alamos, NM); Letvin, Norman (Boston, MA); Haynes, Barton F. (Durham, NC); Hahn, Beatrice H. (Birmingham, AL); Yusim, Karina (Los Alamos, NM); Kuiken, Carla (Los Alamos, NM)

2012-02-21T23:59:59.000Z

212

HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?  

Science Journals Connector (OSTI)

The Tat protein of HIV-1 is a powerful activator of viral ... expression. Besides this essential function at the HIV-1 promoter, the protein also exerts a...Retrovirology...provide possible molecular mechanisms f...

Mauro Giacca

2005-02-01T23:59:59.000Z

213

RNAs selected in vitro by the HIV-2 tat protein  

Science Journals Connector (OSTI)

The Tat proteins of human immunodeficiency virus types 1 (HIV-1) and 2 (HIV-2), termed Tat-1 and Tat-2, respectively, are essential for efficient viral replication. Tat proteins activate viral transcription by bi...

Hyangshuk Rhim; Andrew P. Rice

214

The Role of HIV-1 Proteins in Alzheimer's Disease Pathology.  

E-Print Network [OSTI]

??Prevalence of HIV-associated cognitive impairment is rising, the worst form of which is HIV-associated dementia (HAD). The disease is fuiled by a chronic innate type… (more)

Giunta, Brian Nelson

2011-01-01T23:59:59.000Z

215

E-Print Network 3.0 - anti tb vaccine Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

7 Developing effective tuberculosis (TB) vaccines is a high priority. We use mathematical models to predict the Summary: Developing effective tuberculosis (TB) vaccines is a high...

216

E-Print Network 3.0 - adenoviral vaccine boost Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Developing effective tuberculosis (TB) vaccines is a high priority. We use mathematical models to predict the Summary: pro- vided nearly 83 million in grants to boost TB vaccine...

217

E-Print Network 3.0 - adoption polio vaccines Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Public Perceptions and Stability in Vaccine Uptake Summary: of endemic measles Jansen et al., 2003. Similarly, rumors that the polio vaccine could cause sterility... and...

218

E-Print Network 3.0 - antigen-based malaria vaccine Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

vaccine efficacy trial, Alonso et... is given by a malaria vaccine trial ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

219

E-Print Network 3.0 - antigen vaccine protects Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

antigen of B. parapertussis and its inclusion can substantially improve whooping cough vaccine... ). These vaccines contain only B. pertussis-derived antigens and confer...

220

E-Print Network 3.0 - anti-pneumococcal vaccine era Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of Delaware Collection: Materials Science ; Biotechnology 30 e-publishing Whooping cough Summary: : the pre- vaccine era (from 1983 to 1986, inclusive) and the post-vaccine...

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

E-Print Network 3.0 - anthrax vaccine dead Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

THERE A VACCINE? There is a vaccine available for anthrax, however... FREQUENTLY ASKED QUESTIONS ABOUT ANTHRAX Photos of anthrax from Textbook of Military Medicine... about...

222

NDEP BMP Guide | Open Energy Information  

Open Energy Info (EERE)

BMP Guide Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- OtherOther: NDEP BMP GuideLegal Abstract Nevada Contractors Field Guide for...

223

4-H Meat Goat Guide  

E-Print Network [OSTI]

4-H Meat Goat Guide AS 3-4.060 10 /06 H H H H 1 8 U S C 70 7 #24; 4-H Meat Goat Guide Frank Craddock and Ross Stultz* C ompetition in the show arena is increasing every year as 4-H mem- bers are discovering that goats are an excellent choice...

Craddock, Frank; Stultz, Ross

2006-10-30T23:59:59.000Z

224

Your Health! A Guide for  

E-Print Network [OSTI]

TakeTake Charge o f Your Health! A Guide for Teenagers! #12;#12;A GuideT fe oen r TakeTake agers! Charge Your o f Health! Does your life move at a hectic pace? You may feel stressed from school, after, buy lunch from vending machines, and grab whatever is in the refrigerator for dinner when you get home

Rau, Don C.

225

December 2010 | 23 GUIDED WAVES  

E-Print Network [OSTI]

December 2010 | 23 GUIDED WAVES Tuning Wave Dispersion in Resonant Networks Eyal Feigenbaum with meta-atoms. Resonant guided wave networks (RGWNs) are a new class of artificial photonic material,5 distinct from photonic crystals and metamateri- als, in which localized waves resonate in closed paths

Atwater, Harry

226

Nuclear Engineering A Guide for  

E-Print Network [OSTI]

Nuclear Engineering A Guide for Undergraduate Majors Last modified Fall 2014 This guide applies-7451, Internet: www.engr.wisc.edu/ep/ #12;1 Introduction The Nuclear Engineering Program is administered to provide Nuclear Engineering undergraduate students with information that will facilitate their studies

Schulte, Mike

227

Effects of HIV Tat on HPV-containing oral keratinocytes.  

Science Journals Connector (OSTI)

...Res, Volume 46, 2005 Effects of HIV Tat on HPV-containing oral keratinocytes...combined effect of high risk HPV and HIV Tat on malignant cell transformation of...with retrovirus capable of expressing HIV Tat. Expression of Tat in this cell line...

Ji Min Yochim; Reuben Kim; Mo-Kwan Kang; Ki-Hyuk Shin; and No-Hee Park

2005-05-01T23:59:59.000Z

228

Click Dimers To Target HIV TAR RNA Conformation Sunil Kumar,  

E-Print Network [OSTI]

toward HIV TAR RNA, when compared to the fluorescent Tat peptide, and show increased selectivity over acid protein) and regulates the level of transcription of HIV.4,5 The cooperative interaction of TatClick Dimers To Target HIV TAR RNA Conformation Sunil Kumar, Patrick Kellish, W. Edward Robinson

Stuart, Steven J.

229

Cell Host & Microbe HIV Evades RNA Interference Directed at TAR  

E-Print Network [OSTI]

in a sequence-specific manner using shRNAs targeting the viral genome. HIV gag, pol, tat, rev, env, vif, and nefCell Host & Microbe Article HIV Evades RNA Interference Directed at TAR by an Indirect Compensatory@berkeley.edu DOI 10.1016/j.chom.2008.09.008 SUMMARY HIV can rapidly evolve when placed under selective pressure

Schaffer, David V.

230

Using the social ecological model to understand the contextual factors associated with HIV risk in commercial sex workers at high risk for contracting HIV  

E-Print Network [OSTI]

and the Perceived Risk of Contracting HIV in a Drug Usingsex workers at high risk for contracting HIV A dissertationsex workers at high risk for contracting HIV by Sandra Erika

Larios, Sandra Erika

2008-01-01T23:59:59.000Z

231

Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator.  

Science Journals Connector (OSTI)

...long terminal repeat and the HIV- 1 Tat transactivator V Desai-Yajnik...H)- one], which inhibits Tat-mediated transactivation of HIV-1, also inhibits the functional...long terminal repeat and the HIV-1 Tat transactivator. | Thyroid hormone...

V Desai-Yajnik; E Hadzic; P Modlinger; S Malhotra; G Gechlik; H H Samuels

1995-08-01T23:59:59.000Z

232

Discussions of adolescent sexuality in news media coverage of the HPV vaccine  

Science Journals Connector (OSTI)

Abstract Given the sexually transmitted nature of human papillomavirus (HPV), some worry the HPV vaccine will create a false sense of security and promote adolescent sexual activity. Media coverage of vaccines can influence social norms, parental attitudes, and vaccine acceptance; in this paper we examine U.S. news media messages related to sexuality and HPV vaccination. Drawing on a structured analysis of 447 articles published during 2005–2009, we qualitatively analyzed a purposive sample of 49 articles discussing adolescent health behaviors related to HPV vaccination. Commonly, articles discussed vaccination in the context of abstinence-only versus comprehensive sexual health education; cited research findings to support vaccination or sex education; argued against connecting vaccination to promiscuous behavior; but included fear-inducing messages. Media messages concerning health behaviors related to HPV vaccination tended to support government and parental involvement in sex education, and dismiss concerns linking vaccination to sexual activity, while also presenting the vaccine as lifesaving.

Dana M. Casciotti; Katherine C. Smith; Amy Tsui; Ann C. Klassen

2014-01-01T23:59:59.000Z

233

New User Guide | Argonne Leadership Computing Facility  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Documentation Feedback Please provide feedback to help guide us as we continue to build documentation for our new computing resource. Feedback Form New User Guide USER TIP:...

234

UESC Contracting Guide | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

UESC Contracting Guide UESC Contracting Guide Presentation-given at the Fall 2011 Federal Utility Partnership Working Group (FUPWG) meeting-provides guidance on utility energy...

235

Caltrans Encroachment Permit Application Guide | Open Energy...  

Open Energy Info (EERE)

Permit Application Guide Jump to: navigation, search OpenEI Reference LibraryAdd to library PermittingRegulatory Guidance - GuideHandbook: Caltrans Encroachment Permit...

236

Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral therapy  

E-Print Network [OSTI]

Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral-time PCR assay in multiple samples per patient with a median (interquartile range) follow-up of 76 (45­102) weeks. Results: The median (range) baseline HIV-1 DNA load was 297 (, 10 to 3468) copies per 1 3 106

237

Surveillance Guides - Continous Improvement  

Broader source: Energy.gov (indexed) [DOE]

CONTINUOUS IMPROVEMENT CONTINUOUS IMPROVEMENT 1.0 Objective The objective of this surveillance is to verify that contractor personnel are effectively managing environment, safety, and health issues in a manner that fosters continuous improvement. The activities included in this surveillance help the Facility Representative determine whether safety issues identified through internal contractor, and external DOE or Defense Nuclear Facilities Safety Board evaluation programs are resolved consistent with the level of safety importance. 2.0 References 2.1 DOE O 414.1, Quality Assurance 2.2 DOE O 232.1, Occurrence Reporting and Processing of Operations Information 2.3 DOE-STD-1045-93, Guide to Good Practices for Notifications and Investigations of Abnormal Events 2.4 48 CFR 1970.5204, Department of Energy Acquisition

238

Source Selection Guide  

Broader source: Energy.gov (indexed) [DOE]

32.1 (October 2011) 32.1 (October 2011) 1 Reviewing and Approving Contract Invoices References FAR Part 31 - Contract Cost Principles and Procedures FAR Part 32 - Contract Financing FAR Part 42 - Contract Administration and Audit Services FAR Subpart 52.232 - Contract Clauses DEAR Part 931 - Contract Cost Principles and Procedures DEAR Part 932 - Contract Financing DEAR Part 942 - Contract Administration DOE O 361.1B - Acquisition Career Management Program DOE O 541.1B - Appointment of Contracting Officers and Contracting Officer Representatives Overview The purpose of this Guide Chapter is to provide guidance for ensuring that invoices/vouchers are properly reviewed and analyzed prior to making any payments to contractors (for the purposes of

239

users-guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Contents Contents Contents Contents ARGONNE NATIONAL LABORATORY 9700 South Cass Avenue Argonne, IL 60439 in ANL/MCS-TM-234 Users Guide for ROMIO: A High-Performance, Portable MPI-IO Implementation by Rajeev Thakur, Robert Ross, Ewing Lusk, William Gropp, Robert Latham Mathematics and Computer Science Division Technical Memorandum No. 234 Revised May 2004, November 2007, April 2010 This work was supported by the Mathematical, Information, and Computational Sciences Division subprogram of the Office of Advanced Scientific Computing Research, U.S. Department of Energy, under Contract W-31-109-Eng-38; and by the Scalable I/O Initiative, a multiagency project funded by the Defense Advanced Research Projects Agency (Contract DABT63-94-C-0049), the Department of Energy, the National Aeronautics and Space Administration,

240

Source Selection Guide  

Broader source: Energy.gov (indexed) [DOE]

------------------ Chapter 31.4 (April 2013) ------------------ Chapter 31.4 (April 2013) Allowability of Incurred Costs References FAR Part 31 Contract Cost Principles and Procedures DEAR Subpart 970.31 Contract Cost Principles and Procedures DEAR Part 931 Contract Cost Principles and Procedures I. Overview This guide chapter discusses determining the allowability of incurred costs, emphasizing the five FAR requirements, especially the reasonableness requirement. The chapter requires Contracting Officers, when reviewing current advance agreements or establishing new advance agreements, to ensure they: (1) neither provide that a cost unallowable per FAR Part 31 or applicable DOE cost principles is allowable nor agree to any other treatment of costs inconsistent with FAR Part 31 or applicable DOE cost principles; and (2) emphasize that

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Small caliber guided projectile  

DOE Patents [OSTI]

A non-spinning projectile that is self-guided to a laser designated target and is configured to be fired from a small caliber smooth bore gun barrel has an optical sensor mounted in the nose of the projectile, a counterbalancing mass portion near the fore end of the projectile and a hollow tapered body mounted aft of the counterbalancing mass. Stabilizing strakes are mounted to and extend outward from the tapered body with control fins located at the aft end of the strakes. Guidance and control electronics and electromagnetic actuators for operating the control fins are located within the tapered body section. Output from the optical sensor is processed by the guidance and control electronics to produce command signals for the electromagnetic actuators. A guidance control algorithm incorporating non-proportional, "bang-bang" control is used to steer the projectile to the target.

Jones, James F. (Albuquerque, NM); Kast, Brian A. (Albuquerque, NM); Kniskern, Marc W. (Albuquerque, NM); Rose, Scott E. (Albuquerque, NM); Rohrer, Brandon R. (Albuquerque, NM); Woods, James W. (Albuquerque, NM); Greene, Ronald W. (Albuquerque, NM)

2010-08-24T23:59:59.000Z

242

Radiation Protection Programs Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide amplifies the regulatory requirements of 10 CFR 835 and provides explanations and examples of the basic requirements for implementing the requirements of 10 CFR 835. Cancels DOE G 441.1-1A, DOE G 441.1-2, DOE G 441.1-3A, DOE G 441.1-4A, DOE G 441.1-5, DOE G 441.1-6, DOE G 441.1-7, DOE G 441.1-8, DOE G 441.1-9, DOE G 441.1-10, DOE G 441.1-11, DOE G 441.1-12, DOE G 441.1-13. Canceled by DOE G 441.1-1C.

2007-03-01T23:59:59.000Z

243

Tank characterization reference guide  

SciTech Connect (OSTI)

Characterization of the Hanford Site high-level waste storage tanks supports safety issue resolution; operations and maintenance requirements; and retrieval, pretreatment, vitrification, and disposal technology development. Technical, historical, and programmatic information about the waste tanks is often scattered among many sources, if it is documented at all. This Tank Characterization Reference Guide, therefore, serves as a common location for much of the generic tank information that is otherwise contained in many documents. The report is intended to be an introduction to the issues and history surrounding the generation, storage, and management of the liquid process wastes, and a presentation of the sampling, analysis, and modeling activities that support the current waste characterization. This report should provide a basis upon which those unfamiliar with the Hanford Site tank farms can start their research.

De Lorenzo, D.S.; DiCenso, A.T.; Hiller, D.B.; Johnson, K.W.; Rutherford, J.H.; Smith, D.J. [Los Alamos Technical Associates, Kennewick, WA (United States); Simpson, B.C. [Westinghouse Hanford Co., Richland, WA (United States)

1994-09-01T23:59:59.000Z

244

The influence of altruism on influenza vaccination decisions  

Science Journals Connector (OSTI)

...figure 3). For an outbreak with a cumulative...a major influenza outbreak with a cumulative...60 per cent, our model predicted that 52...combinations for the flu season. J. Econ...susceptible-infected epidemic model with voluntary vaccinations...Imitation dynamics predict vaccinating behaviour...

2012-01-01T23:59:59.000Z

245

Impact of Varicella Vaccine on Varicella-Zoster Virus Dynamics  

Science Journals Connector (OSTI)

...study of vaccinated children in Japan showed that VZV titers were...illness were twice as common for household contacts rather than hospital...FRET, fluorescence resonance energy transfer. TABLE 2. Studies...varicella in vaccinated cases: a household contact study. JAMA 292...

D. Scott Schmid; Aisha O. Jumaan

2010-01-01T23:59:59.000Z

246

Fractional Doses of Inactivated Poliovirus Vaccine in Oman  

Science Journals Connector (OSTI)

...paracetamol, and instructions were given to parents to administer 50 mg every 8 hours for 3 days. Infants were evaluated for adverse events through home visits conducted at 24 hours after each vaccination by qualified medical staff members who were aware of the study-vaccination assignments. In addition... Determining an economically sustainable way to deliver the poliovirus vaccine remains a challenge and a priority. In this article, investigators in Oman show that with a one-fifth dose of the inactivated poliovirus vaccine given intradermally, the seroconversion rates at 7 months of age to all three poliovirus serotypes were equivalent to the rates with the standard full-dose vaccine given intramuscularly. However the median antibody titers were lower with the fractional dose than with the full dose.

Mohammed A.J.; AlAwaidy S.; Bawikar S.

2010-06-24T23:59:59.000Z

247

Self-Guided Quantum Tomography  

Science Journals Connector (OSTI)

We introduce a self-learning tomographic technique in which the experiment guides itself to an estimate of its own state. Self-guided quantum tomography uses measurements to directly test hypotheses in an iterative algorithm which converges to the true state. We demonstrate through simulation on many qubits that Self-guided quantum tomography is a more efficient and robust alternative to the usual paradigm of taking a large amount of informationally complete data and solving the inverse problem of postprocessed state estimation.

Christopher Ferrie

2014-11-07T23:59:59.000Z

248

Decreased T-Cell Responses to Influenza Vaccination in Patients with Heart Failure  

E-Print Network [OSTI]

Decreased T-Cell Responses to Influenza Vaccination in Patients with Heart Failure Orly Vardeny vaccination in patients with chronic heart failure (CHF) are less vigorous than the responses of healthy strategies for influenza vaccination. Key Words: chronic heart failure, CHF, influenza vaccination, immune

Wisconsin at Madison, University of

249

Technical Standards, Style Guide- August 1, 2000  

Broader source: Energy.gov [DOE]

Style Guide for the Preparation of DOE Technical Standards (Standards, Handbooks, and Technical Standards Lists)

250

CALIFORNIA ENERGY Small HVAC System Design Guide  

E-Print Network [OSTI]

CALIFORNIA ENERGY COMMISSION Small HVAC System Design Guide DESIGNGUIDELINES October 2003 500;#12;Small HVAC System Design Guide Acknowledgements i Acknowledgements The products and outcomes presented; Darren Goody, PECI, Design Guide review. #12;Small HVAC System Design Guide Preface ii Preface The Small

251

CEQ NEPA & EMS Guide  

Broader source: Energy.gov (indexed) [DOE]

National Environmental Policy Act Processes with Environmental Management Systems c o u n c i l o n e n v i r o n m e n t a l q u a l i t y A Guide for NEPA and EMS Practitioners a p r i l 2 0 0 7 Preface This guide builds on research and consultations undertaken by the Council on Environmental Quality (CEQ) on the complementary aspects of the National Environmental Policy Act (NEPA) and Environmental Management Systems (EMS). It introduces issues and provides information on how NEPA and EMS can be aligned. This guide does not establish new requirements, does not constitute formal CEQ guidance, and its recommendations should not be considered legally binding. A Guide for NEPA and EMS Practitioners  Aligning National Environmental Policy Act Processes with Environmental Management Systems

252

CCD Astronomy Software User's Guide  

E-Print Network [OSTI]

CCDSoft CCD Astronomy Software User's Guide Version 5 Revision 1.11 Copyright © 1992­2006 SantaSky Astronomy Software, and AutomaDome are trademarks of Software Bisque. WindowsTM is a trademark of Microsoft

253

FAQS Reference Guide –Radiation Protection  

Broader source: Energy.gov [DOE]

This reference guide has been developed to address the competency statements in the December 2003 edition of DOE-STD-1174-2003, Radiation Protection Functional Area Qualification Standard.

254

FAQS Reference Guide – Occupational Safety  

Broader source: Energy.gov [DOE]

This reference guide has been developed to address the competency statements in the July 2011 version of DOE-STD-1160-2011, Occupational Safety Functional Area Qualification Standard.

255

Regulatory Facility Guide for Tennessee  

SciTech Connect (OSTI)

This guide provides detailed compilations of international, federal, and state transportation related regulations applicable to shipments originating at or destined to Tennessee facilities. Information on preferred routes is also given.

Anderson, S.S.; Bock, R.E.; Francis, M.W.; Gove, R.M.; Johnson, P.E.; Kovac, F.M.; Mynatt, J.O. [Oak Ridge National Lab., TN (United States); Rymer, A.C. [Transportation Consulting Services, Knoxville, TN (United States)

1994-02-28T23:59:59.000Z

256

Model Fire Protection Assessment Guide  

Broader source: Energy.gov [DOE]

This Assessment guide covers the implementation of the DOE's responsibility of assuring that DOE and the DOE Contractors have established Fire Protection Programs that are at the level required for the area being assessed.

257

Staffing Guide for Project Management  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide provides an approach to determining the appropriate level and type of federal personnel needed to effectively plan, direct, and oversee project execution. Admin Chg 1, dated 10-12-11, cancels DOE G 413.3-19.

2010-06-03T23:59:59.000Z

258

Data Contribution Best Practices Guide  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Data Contribution Best Practices Guide Step 1. Decide Which Data to Contribute. If you already have data, the LBNL team strives to make it as easy as possible to contribute it....

259

FAQS Reference Guide – Quality Assurance  

Broader source: Energy.gov [DOE]

This reference guide has been developed to address the competency statements in the April 2002 edition of DOE-Standard (STD)-1150-2002, Quality Assurance Functional Area Qualification Standard.

260

Solid-State Lighting: Product Performance Guides  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Product Performance Guides to Product Performance Guides to someone by E-mail Share Solid-State Lighting: Product Performance Guides on Facebook Tweet about Solid-State Lighting: Product Performance Guides on Twitter Bookmark Solid-State Lighting: Product Performance Guides on Google Bookmark Solid-State Lighting: Product Performance Guides on Delicious Rank Solid-State Lighting: Product Performance Guides on Digg Find More places to share Solid-State Lighting: Product Performance Guides on AddThis.com... Conferences & Meetings Presentations Publications Postings Articles Program Fact Sheets Technology Fact Sheets CALiPER Reports GATEWAY Reports LED Lighting Facts Reports Project Reports Studies and Reports Technology Roadmaps Product Performance Guides Webcasts Videos Tools Product Performance Guides

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Exploring the Roles of Geographic and Neighborhood Level Factors on HPV Vaccine Access and Uptake among Low-income Populations in Los Angeles County  

E-Print Network [OSTI]

2008). "Health and economic implications of HPV vaccination2008). "Health and economic implications of HPV vaccination2008). "Health and economic implications of HPV vaccination

Tsui, Jennifer

2012-01-01T23:59:59.000Z

262

Norwegian petroleum guide  

SciTech Connect (OSTI)

This is about the comprehensive guide to Norwegian oil and gas activities, very useful to anyone in the industry. Material includes political guidelines, control institutions, work possibilities and licenses, working environment law, employer and employee organizations, national insurance, taxes, communication, rescue operations and standby. Contents: Oil and the economy; Petroleum technology research; Responsibilities of different authorities; The Labour Inspection Directorate; The Health Directorate Offshore Office; The Coastal Directorate; Helicopter traffic; The Norwegian Petroleum Directorate; The Maritime Directorate; Det norske Veritas; The Norwegian Waterways and Electricity Board; The State Institute for Radiation Hygiene; The State Explosive Inspection; Work possibilities in the North Sea; Working environment legislation on the Continental Shelf; Collective bargaining agreements, labor conflicts and the right to organize; Taxation Rules; National health insurance and the petroleum activity; Occupational injuries on the Norwegian Continental Shelf; Company insurances; The private pension scheme; Other types of insuracne common among oil companies; The rescue service in Norway; Oganizations within the oil industry offshore and onshore; and Law of aliens admission to the Kindgom.

Christie, H.B.

1984-01-01T23:59:59.000Z

263

Fatigue monitoring desktop guide  

SciTech Connect (OSTI)

The development of a program for managing material aging (MMG) in the nuclear industry requires a new and different perspective. The classical method for MMG is cycle counting, which has been shown to have limited success. The classical method has been successful in satisfying the ductile condition per the America Society of Mechanical Engineers' (ASME) design criteria. However, the defined material failure mechanism has transformed from through-wall cracking and leakage (ASME) to crack initiation (NUREG-6909). This transformation is based on current industry experience with material degradation early in plant life and can be attributed to fabrication issues and environment concerns where cycle counting has been unsuccessful. This new perspective provides a different approach to cycle counting that incorporates all of the information about the material conditions. This approach goes beyond the consideration of a static analysis and includes a dynamic assessment of component health, which is required for operating plants. This health definition should consider fabrication, inspections, transient conditions and industry operating experience. In addition, this collection of information can be transparent to a broader audience that may not have a full understanding of the system design or the potential causes of early material degradation. This paper will present the key points that are needed for a successful fatigue monitoring desktop guide. (authors)

Woods, K. [InnoTech Engineering Solutions, LLC (United States); Thomas, K. [Nebraska Public Power District (United States)

2012-07-01T23:59:59.000Z

264

UAL USER GUIDE.  

SciTech Connect (OSTI)

The Unified Accelerator Libraries (UAL) provide a modularized environment for applying diverse accelerator simulation codes. Development of UAL is strongly prejudiced toward1 importing existing codes rather than developing new ones. This guide provides instructions for using this environment. This includes instructions for acquiring and building the codes, then for launching and interpreting some of the examples included with the distribution. In some cases the examples are general enough to be applied to different accelerators by mimicking input files and input parameters. The intention is to provide just enough computer language discussion (C++ and Perl) to support the use and understanding of the examples and to help the reader gain a general understanding of the overall architecture. Otherwise the manual is ''documentation by example.'' Except for an appendix concerning maps, discussion of physics is limited to comments accompanying the numerous code examples. Importation of codes into UAL is an ongoing enterprise and when a code is said to have been Imported it does not necessarily mean that all features are supported. Other than this, the original documentation remains applicable (and is not duplicated here.)

MALITSKY,N.; TALMAN,R.

2003-01-09T23:59:59.000Z

265

Table of Contents for Desk Guide  

Broader source: Energy.gov (indexed) [DOE]

Real Estate Desk Guide Real Estate Desk Guide Revised May, 2013 U. S. Department of Energy - Real Estate Desk Guide Revised 2013 Real Estate Desk Guide Table of Contents Chapter 1-- Purpose of Desk Guide ........................................................................ 1 Chapter 2-- Introduction ......................................................................................... 3 Chapter 3-- Planning Policy .................................................................................... 7 Chapter 4-- Real Estate Function ......................................................................... 10 Chapter 5-- Acquisition of Interests in Real Property ........................................ 14 Chapter 6-- Acquisition by Lease ......................................................................... 34

266

Model Year 1999 Fuel Economy Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

FUEL FUEL ECONOMY GUIDE MODEL YEAR 1999 DOE/EE-0178 Fuel Economy Estimates October 1998 1 CONTENTS PAGE Purpose of the Guide ..................................................... 1 Interior Volume ................................................................ 1 How the Fuel Economy Estimates are Obtained ........... 1 Factors Affecting MPG .................................................... 2 Fuel Economy and Climate Change ............................... 2 Gas Guzzler Tax ............................................................. 2 Vehicle Classes Used in This Guide. .............................. 2 Annuel Fuel Costs .......................................................... 3 How to Use the Guide .................................................... 4 Where to Re-order Guides

267

Table of Contents for Desk Guide  

Broader source: Energy.gov (indexed) [DOE]

Real Estate Desk Guide Real Estate Desk Guide Revised May, 2013 U. S. Department of Energy - Real Estate Desk Guide Revised 2013 Real Estate Desk Guide Table of Contents Chapter 1-- Purpose of Desk Guide ........................................................................ 1 Chapter 2-- Introduction ......................................................................................... 3 Chapter 3-- Planning Policy .................................................................................... 7 Chapter 4-- Real Estate Function ......................................................................... 10 Chapter 5-- Acquisition of Interests in Real Property ........................................ 14 Chapter 6-- Acquisition by Lease ......................................................................... 34

268

Evaluation of a computer-based system using cell phones for hiv positive people in peru  

Science Journals Connector (OSTI)

HIV is one of the biggest infectious killers worldwide. To prevent disease progression and avoid development of resistant strains to HIV, people living with HIV must adhere to complicated antiretroviral therapy (ART). Yet, in Peru, where ART has recently ...

Walter H. Curioso / Wanda Pratt

2012-01-01T23:59:59.000Z

269

E-Print Network 3.0 - ao hiv em Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Ex Vivo-Expanded Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Infusion in HIV-Infected Patients Summary: , Edwards lack of disease in HIV-1-infected...

270

Liver histopathology in patients with concurrent chronic hepatitis C and HIV infection  

Science Journals Connector (OSTI)

To investigate the influence of human immunodeficiency virus (HIV) coinfection on preexisting long-term chronic C hepatitis (HCV) 68 liver biopsies from 22 HIV/HCV-coinfected, 13 HIV and 33 HCV-monoinfected pa...

E. Bierhoff; H. -P. Fischer; E. Willsch; J. Rockstroh; U. Spengler…

1997-04-01T23:59:59.000Z

271

Jembrana Disease Virus Tat Can Regulate Human Immunodeficiency Virus (HIV) Long Terminal Repeat-Directed Gene Expression and Can Substitute for HIV Tat in Viral Replication  

Science Journals Connector (OSTI)

...Expression and Can Substitute for HIV Tat in Viral Replication Hexin Chen Jun...virus (HIV) LTR. In contrast, HIV Tat cannot reciprocally activate the JDV...to but not the same as that of the HIV Tat. To further study the similarity...

Hexin Chen; Jun He; Steven Fong; Graham Wilcox; Charles Wood

2000-03-01T23:59:59.000Z

272

HIV-1 TAT IS A NATIVELY UNFOLDED PROTEIN: THE SOLUTION CONFORMATION AND DYNAMICS OF REDUCED HIV-1 TAT1-72 BY NMR  

E-Print Network [OSTI]

1 HIV-1 TAT IS A NATIVELY UNFOLDED PROTEIN: THE SOLUTION CONFORMATION AND DYNAMICS OF REDUCED HIV-1 59 nucleotides of the HIV-1 RNA (4). Tat stimulates elongation of full-length transcripts implicated in HIV-1 latency (1). Tat may also be involved in derepression of heterochromatin, transcription

O'Neil, Joe

273

EERE Program Management Guide - Appendix H  

Broader source: Energy.gov (indexed) [DOE]

H H Model Senior Executive Services Performance Appraisal H-1 December 2007 http://www1.eere.energy.gov/ba/prog_mgmt_guide.html SAMPLE EERE Program Management Guide Appendix H-Model Senior Executive Service Performance Appraisal December 2007 http://www1.eere.energy.gov/ba/prog_mgmt_guide.html SAMPLE H-2 EERE Program Management Guide Appendix H-Model Senior Executive Service Performance Appraisal December 2007 http://www1.eere.energy.gov/ba/prog_mgmt_guide.html SAMPLE H-3 EERE Program Management Guide Appendix H-Model Senior Executive Service Performance Appraisal December 2007 http://www1.eere.energy.gov/ba/prog_mgmt_guide.html SAMPLE H-4 EERE Program Management Guide Appendix H-Model Senior Executive Service Performance Appraisal December 2007 http://www1.eere.energy.gov/ba/prog_mgmt_guide.html

274

Building Technologies Office: Advanced Energy Design Guides  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Energy Design Energy Design Guides to someone by E-mail Share Building Technologies Office: Advanced Energy Design Guides on Facebook Tweet about Building Technologies Office: Advanced Energy Design Guides on Twitter Bookmark Building Technologies Office: Advanced Energy Design Guides on Google Bookmark Building Technologies Office: Advanced Energy Design Guides on Delicious Rank Building Technologies Office: Advanced Energy Design Guides on Digg Find More places to share Building Technologies Office: Advanced Energy Design Guides on AddThis.com... About Take Action to Save Energy Activities 179d Tax Calculator Advanced Energy Design Guides Advanced Energy Retrofit Guides Building Energy Data Exchange Specification Buildings Performance Database Data Centers Energy Asset Score Energy Modeling Software

275

Wave guide impedance matching method and apparatus  

DOE Patents [OSTI]

A technique for modifying the end portion of a wave guide, whether hollow or solid, carrying electromagnetic, acoustic or optical energy, to produce a gradual impedance change over the length of the end portion, comprising the cutting of longitudinal, V-shaped grooves that increase in width and depth from beginning of the end portion of the wave guide to the end of the guide so that, at the end of the guide, no guide material remains and no surfaces of the guide as modified are perpendicular to the direction of energy flow. For hollow guides, the grooves are cut beginning on the interior surface; for solid guides, the grooves are cut beginning on the exterior surface. One or more resistive, partially conductive or nonconductive sleeves can be placed over the exterior of the guide and through which the grooves are cut to smooth the transition to free space.

Kronberg, James W. (Beech Island, SC)

1990-01-01T23:59:59.000Z

276

E-Print Network 3.0 - access hiv-1 test Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Strains in Newly- Summary: Cellular HIV-1 DNA Levels in Drug Sensitive Strains Are Equivalent to Those in Drug Resistant... , Leuven, Belgium Abstract Background: HIV-1...

277

E-Print Network 3.0 - antiretroviral hiv post-exposure Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HIV in Summary: EDITORIAL REVIEW The antiretroviral rollout and drug-resistant HIV in Africa: insights from... of this plan is to provide antiretroviral treatment to millions of...

278

Solar Water Heating: SPECIFICATION, CHECKLIST AND GUIDE | Department...  

Energy Savers [EERE]

Solar Water Heating: SPECIFICATION, CHECKLIST AND GUIDE Solar Water Heating: SPECIFICATION, CHECKLIST AND GUIDE Solar Water Heating: SPECIFICATION, CHECKLIST AND GUIDE, from the...

279

Water Management Guide - Building America Top Innovation | Department...  

Energy Savers [EERE]

Water Management Guide - Building America Top Innovation Water Management Guide - Building America Top Innovation Cover of the EEBA Water Management Guide. As energy codes and...

280

Natural Gas Study Guide - Middle School | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Middle School Natural Gas Study Guide - Middle School Natural Gas Study Guide - Middle School More Documents & Publications Natural Gas Study Guide - High School What is shale gas?...

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Procuring Solar Energy Guide Contacts | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Procuring Solar Energy Guide Contacts Procuring Solar Energy Guide Contacts Contact information for the Procuring Solar Energy: A Guide for Federal Facility Decision Makers is...

282

Guide to Federal Financing for Energy Efficiency and Clean Energy...  

Energy Savers [EERE]

Guide to Federal Financing for Energy Efficiency and Clean Energy Deployment Guide to Federal Financing for Energy Efficiency and Clean Energy Deployment Editor's note: This guide...

283

A Design Guide for Early-Market Electrochromic Windows  

E-Print Network [OSTI]

Guide for Early-Market Electrochromic Windows. CaliforniaGuide for Early-Market Electrochromic Windows. CaliforniaGUIDE FOR EARLY-MARKET ELECTROCHROMIC WINDOWS Prepared For:

2006-01-01T23:59:59.000Z

284

Software Quality: A Guide to Responsibilities and Resources,...  

Office of Environmental Management (EM)

Software Quality: A Guide to Responsibilities and Resources, SQAS Software Quality: A Guide to Responsibilities and Resources, SQAS This Guide provides guidance to the software...

285

Council on Environmental Quality - A Citizen's Guide to the NEPA...  

Open Energy Info (EERE)

to library PermittingRegulatory Guidance - GuideHandbook: Council on Environmental Quality - A Citizen's Guide to the NEPAPermittingRegulatory GuidanceGuideHandbook Abstract...

286

Protocol, Test Inspectors Guide - March 2008 | Department of...  

Broader source: Energy.gov (indexed) [DOE]

Test Inspectors Guide - March 2008 Protocol, Test Inspectors Guide - March 2008 March 2008 Emergency Management Limited Scope Performance Test Inspectors Guide This Emergency...

287

Oil Study Guide - Middle School | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Middle School Oil Study Guide - Middle School Oil Study Guide - Middle School More Documents & Publications Oil Study Guide - High School evaluationegstech2008.pdf A History of...

288

AIDS Vaccination Studies Using an Ex Vivo Feline Immunodeficiency Virus Model: Detailed Analysis of the Humoral Immune Response to a Protective Vaccine  

Science Journals Connector (OSTI)

...time interval between completion of vaccination and challenge...in vitro-measurable indices of protective immunity...challenged 4 months after completion of the primary vaccination...various times after completion of primary vaccination...wells. A conformation index was calculated for each...

Paola Mazzetti; Simone Giannecchini; Daniela Del Mauro; Donatella Matteucci; Pietro Portincasa; Antonio Merico; Carlo Chezzi; Mauro Bendinelli

1999-01-01T23:59:59.000Z

289

Ebola Virus Pathogenesis: Implications for Vaccines and Therapies  

Science Journals Connector (OSTI)

...American Society for Microbiology MINIREVIEW Ebola Virus Pathogenesis: Implications for Vaccines...Institutes of Health, Bethesda, Maryland Ebola virus is an aggressive pathogen that causes...nonhuman primates. First recognized near the Ebola River valley during an outbreak in Zaire...

Nancy Sullivan; Zhi-Yong Yang; Gary J. Nabel

2003-09-01T23:59:59.000Z

290

Membrane Vesicles as a Vaccine Platform For Salmonella  

E-Print Network [OSTI]

. Current vesicle vaccine platforms include inactivated, non-replicating, or synthetic liposomes which do not produce a robust immune response because they lack foreign distinctness and complexity. Membrane vesicles (MVs), released in a conserved process...

Hinkley, Megan L

2012-07-11T23:59:59.000Z

291

Implications of a Circulating Vaccine-Derived Poliovirus in Nigeria  

Science Journals Connector (OSTI)

Since 1988, when the World Health Assembly resolved to eradicate poliovirus, the annual incidence of paralytic poliomyelitis has fallen by more than 99%. However, the annual number of cases reported for the years 2003 through mid-2009 has remained relatively constant, and continued transmission in endemic... Reversion of live attenuated oral poliovirus vaccine strains to a virulent phenotype is a rare but significant occurrence. In Nigeria, at least one vaccine-derived clone of type 2 poliovirus developed virulence, leading to ongoing transmission networks and many cases of paralysis. In this report, the characteristics of polio-associated disease and attack rates for this vaccine-derived clone are compared with circulating wild-type polioviruses 1 and 3. Increased vaccination efforts have significantly contributed to the control of all three serotypes. Implications for the global effort to eradicate polio are considered.

Jenkins H.E.; Aylward R.B.; Gasasira A.

2010-06-24T23:59:59.000Z

292

SOVIET VIABLE PASTEURELLA TULARENSIS VACCINES A REVIEW OF SELECTED ARTICLES  

Science Journals Connector (OSTI)

...basis for the present operating specification in production...culture media and selection of colonies a new...prophylaxis, inadequate training for medical personnel, and insufficient...vaccination of all personnel and revacci- nation...

W. D. Tigertt

1962-09-01T23:59:59.000Z

293

Standing Orderfor Tdap Vaccine OR Declination Consent and Administration of  

E-Print Network [OSTI]

and it covers Pertussis (\\\\!hooping cough). Tdap normally has a two year interval between a Td and this vaccine (whooping cough), I am at risk ofacquiring Pertussis, a serious disease and could potentially infect others

Leistikow, Bruce N.

294

Program: Self-Guided Tours  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Self-Guided Tours Self-Guided Tours Description: The following options are currently available to visitors who do not plan to take a guided tour. Wilson Hall If permitted by the current security conditions, visitors to the laboratory are welcome to visit the ground floor and atrium of Wilson Hall, the 16-story administrative building. The atrium offers an exhibit, a cafeteria and an information desk. The floors 2 to 16 are closed to the public. To take a tour of the 15th-floor viewing area, please sign up for a guided tour (see information above). Prairie Trails and Buffalo Viewing If permitted by the current security conditions, visitors to the lab can walk along a couple of prairie trails near the Pine Street entrance (west side of the lab) including the Margaret Pearson Interpretive Trail, a quarter mile self-guiding nature trail through a portion of Fermilab's restored prairie. Located on the north side of the Pine Street exit of the site, the trail is open to the public daily from 6:00 AM to 8 PM.

295

HIV-AIDS Information Resources from the NLM - ACIO  

SciTech Connect (OSTI)

As the treatment and management of HIV/AIDS continues to evolve with new scientific breakthroughs, treatment discoveries, and management challenges, it is difficult for people living with HIV/AIDS and those who care for them to keep up with the latest information on HIV/AIDS screening and testing, prevention, treatment, and research. The National Library of Medicine (NLM), of the National Institutes of Health, has a wealth of health information resources freely available on the Internet to address these needs.

Templin-Branner, W.

2010-10-01T23:59:59.000Z

296

Effects of Vaccination on Invasive Pneumococcal Disease in South Africa  

Science Journals Connector (OSTI)

...through December 2012. Duplicate isolates cultured within 21 days after the initial positive culture were excluded. Serotyping and Susceptibility Testing. Pneumococci were serotyped with the use of the quellung reaction (Statens Serum Institut). Serotype 6C was distinguished from 6A throughout. We determined... Invasive pneumococcal disease is an important cause of severe illness. In South Africa, a national program to vaccinate children with the conjugated pneumococcal vaccine resulted in a substantial decline in invasive pneumococcal disease countrywide, including in adults.

von Gottberg A.; de Gouveia L.; Tempia S.

2014-11-13T23:59:59.000Z

297

Vaccine to control the viral infection of fish  

DOE Patents [OSTI]

Subunit vaccines and their use for immunizing fish against infection by viruses are disclosed. In particular, plasmid pG8 is constructed by joining, with the plasmid pUC8, DNA which encodes the glycoprotein of infectious hematopoietic necrosis virus (IHNV). E. coli cells are transformed by pG8, whereby pure viral antigen is produced to provide a vaccine for the control of IHNV in fish.

Leong, Jo-Ann C. (Albany, OR)

1994-10-11T23:59:59.000Z

298

Vaccine to Control the Viral Infection of Fish.  

DOE Patents [OSTI]

Subunit vaccines and their use for immunizing fish against infection by viruses are disclosed. In particular, plasmid pG8 is constructed by joining, with the plasmid pUC8, DNA which encodes the glycoprotein of infectious hematopoietic necrosis virus (IHNV). E. coli cells are transformed by pG8, whereby pure viral antigen is produced to provide a vaccine for the control of IHNV in fish. 10 figs.

Leong, JoAnn Ching

1994-10-11T23:59:59.000Z

299

Australia's Green Vehicle Guide | Open Energy Information  

Open Energy Info (EERE)

Australia's Green Vehicle Guide Australia's Green Vehicle Guide Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Australia's Green Vehicle Guide Agency/Company /Organization: Commonwealth of Australia Focus Area: Vehicles, Fuel Efficiency Topics: Analysis Tools, Market Analysis Website: www.greenvehicleguide.gov.au/GVGPublicUI/home.aspx Equivalent URI: cleanenergysolutions.org/content/australias-green-vehicle-guide,http:/ Language: English Policies: Regulations Regulations: Fuel Efficiency Standards The Green Vehicle Guide provides information about the environmental performance of new light-duty vehicles sold in Australia, including carbon dioxide (CO2) emissions and fuel consumption. The Guide includes resources such as a fuel calculator, electric vehicle information and a truck buyers

300

FTCP Guiding Documents | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Guiding Documents Guiding Documents FTCP Guiding Documents Key FTCP Directives and Guidance DOE Order 426.1 Chg 1, Federal Technical Capability DOE Order 360.1C, Federal Employee Training DOE Guide 226.1-2, Federal Line Management Oversight of Department of Energy Nuclear Facilities FTCP Assessment Guidance and Criteria, 1998 FTCP and TQP Assessment CRADs, 2012 Qualification Standards and Related Information Functional Area Qualification Standards - TEMPLATE - FAQS Training Course Evaluation Guide - Review Process for Technical Standards FAQS Qualification Cards FAQS Gap Analysis Qualification Cards FAQS Reference Guides FAQS Job Task Analyses - Job Task Analyses Form Qualifying Official Training Approaches Sponsors & Recognized Experts for FAQS HFE Supplemental Competencies

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Emergence of HIV-1 Drug Resistance During Antiretroviral Treatment  

E-Print Network [OSTI]

Bulletin of Mathematical Biology (2007). DOI 10.1007/s11538-007-9203-3. ORIGINAL ARTICLE. Emergence of HIV-1 Drug Resistance During Antiretroviral.

2007-08-22T23:59:59.000Z

302

CAPITAL PROGRAMMING GUIDE (PART 7)  

Broader source: Energy.gov (indexed) [DOE]

CAPITAL PROGRAMMING GUIDE CAPITAL PROGRAMMING GUIDE V 2.0 SUPPLEMENT TO OFFICE OF MANAGEMENT AND BUDGET CIRCULAR A-11, PART 7: PLANNING, BUDGETING, AND ACQUISITION OF CAPITAL ASSETS JUNE 2006 CAPITAL PROGRAMMING GUIDE LIST OF ABBREVIATIONS LIST OF ABBREVIATIONS ACP Agency Capital Plan CI Commercial Items COTS Commercial-off-the-shelf ESPC Energy Savings Performance Contract EVM Earned Value Management FAR Federal Acquisition Regulation FARA Federal Acquisition Reform Act (Clinger-Cohen Act) of 1996 1 (Division D of Pub. L. No. 104-106) FASA Federal Acquisition Streamlining Act of 1994 (Pub. L. No. 103-355) FRPC Federal Real Property Council GAO Government Accountability Office GPRA Government Performance and Results Act of 1993 (Pub. L. No. 103-62)

303

Accelerating introduction of new vaccines: barriers to introduction and lessons learned from the recent Haemophilus influenzae type b vaccine experience  

Science Journals Connector (OSTI)

...and policy staff within the Sri Lankan government facilitated...Another example comes from Sri Lanka, where shortly after...communities, vaccine manufacturers, international agencies, donors and more...organization & administration International Cooperation Public-Private...

2011-01-01T23:59:59.000Z

304

HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment  

E-Print Network [OSTI]

mechanism inhibits HIV-1 and Ebola virus particle releasebudding is antagonized by the Ebola glycoprotein. Proc NatlKG, Oldenburg J, Cannon PM: Ebola glycoprotein counteracts

2010-01-01T23:59:59.000Z

305

IT Administrator's Guide to Using Windows Vista  

E-Print Network [OSTI]

IT Administrator's Guide to Using Windows Vista® for Sustainable IT Success Published: February Administrator's Guide to Using Windows Vista for Sustainable IT Success Contents Executive Summary ................................................................................................ 3 Sustainable IT Goals

Narasayya, Vivek

306

BOISE STATE UNIVERSITY THE INVENTOR'S GUIDE  

E-Print Network [OSTI]

to funding from private foundations and commercial sponsors. The invention disclosure process is the first the most common questions regarding inventions, patents and technology commercialization. The guide with industry. For the purposes of this guide, however, technology transfer ("commercialization") refers

Barrash, Warren

307

Guide on Federal Employee Occupational Medical Programs  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide supplements the requirements and responsibilities specified in DOE O 341.1, Federal Employee Health Services, dated 12-1-03. This Guide provides preferred implementing methods and procedures. Canceled by DOE G 341.1-1A.

2003-12-01T23:59:59.000Z

308

Guide to Minimizing Compress-based Cooling  

Broader source: Energy.gov [DOE]

Guide describes best practices for reducing energy use and total-cost-of-ownership for data center cooling systems.

309

EERE Program Management Guide- Appendix P  

Office of Energy Efficiency and Renewable Energy (EERE)

Appendix P provides a comprehensive listing of the references used to formulate the different chapters of this guide.

310

Functional Area Qualification Standard Reference Guides  

Broader source: Energy.gov [DOE]

The reference guides have been developed to address the competency statements in DOE Functional Area Qualification Standard.

311

ENERGY STAR Guide to Retro-Commissioning  

Broader source: Energy.gov [DOE]

ENERGY STAR Guide to Retro-Commissioning gives an overview of RCx and provides detailed project guidance.

312

EERE Program Management Guide- Chapter 1  

Office of Energy Efficiency and Renewable Energy (EERE)

Chapter 1 of this guide provides a background on DOE's and EERE's mission, vision, priorities, and strategies.

313

Pro/INTRALINK Users Guide NCSX-GUID-PRO/INTR-00  

E-Print Network [OSTI]

: ______________________________________ ______________________________________ T Brown, NCSX Design Integration J. Chrzanowski, Mechanical Design Manager Branch HeadNCSX Pro/INTRALINK Users Guide NCSX-GUID-PRO/INTR-00 May 4, 2005 Prepared by:52:43 -04'00' #12;NCSX Pro/INTRALINK Users Guide Pro/INTRALINK Users Guide Revision 0 i Record of Revisions

Princeton Plasma Physics Laboratory

314

Operations & Maintenance Best Practices Guide: Release 3.0  

Broader source: Energy.gov [DOE]

Guide covers version 3.0 of the Operations and Maintenance Best Practices: A Guide to Achieving Operational Efficiency.

315

DOE VPN Client User Guide  

Broader source: Energy.gov (indexed) [DOE]

VPN Client VPN Client User Guide November 2013 U.S. Department of Energy Table of Contents Introduction ................................................................... 3 System Requirements ................................................... 3 Microsoft Windows ........................................................ 3 Mac OS X...................................................................... 4 Windows ......................................................................... 5 Installation for the Cisco AnyConnect Client ................... 5 Disconnecting from the Cisco AnyConnect Client ........... 8 Reconnecting to the Cisco AnyConnect Client ................ 9 Mac OS X ...................................................................... 10

316

Engineering Science Undergraduate Program Guide  

E-Print Network [OSTI]

Engineering Science Undergraduate Program Guide 2011-2012 The Pennsylvania State University Dept. of Engineering Science and Mechanics 212 Earth-Engineering Sciences Building University Park, PA 16802-1401 814 of Engineering Science and Mechanics. The Pennsylvania State University is committed to the policy that all

Demirel, Melik C.

317

RECREATION GUIDE University of Pennsylvania  

E-Print Network [OSTI]

RECREATION GUIDE University of Pennsylvania Department of Recreation 2013-2014 #12;15 14 Amy Wagner Director of Recreation wagneram@pobox.upenn.edu PROGRAMS Christian Bosch Associate Director, Programs@upenn.edu Tricia DePoe Associate Director, Facilities tdepoe@upenn.edu Dan Bradley Assistant Director, Recreation

Plotkin, Joshua B.

318

Guide to the Library Locations  

E-Print Network [OSTI]

Guide to the Libraries #12;Library Locations W.E.B. DU BOIS LIBRARY www.library.umass.edu 154 Hicks Way (413) 545-0150, (413) 545-2622 The Du Bois Library is the primary location for resources machine, and a fax machine. Quiet study space is located on Floors 2 and 3 and throughout the upper floors

Massachusetts at Amherst, University of

319

LOCUS User's Guide Steve Scott  

E-Print Network [OSTI]

LOCUS User's Guide Steve Scott March, 2005 Last updated November 22, 2005 LOCUS is a database of the listed options, e.g. `Y' to define the variable to be plotted on the y-axis or `PL' to plot the data of items, e.g. a list of constraints, entering a semi-colon (";") terminates the list. For example, SET? X

Princeton Plasma Physics Laboratory

320

INLAND PORT TRANSPORTATION EVALUATION GUIDE  

E-Print Network [OSTI]

INLAND PORT TRANSPORTATION EVALUATION GUIDE by Robert Harrison, Center for Transportation Research Transportation Institute, The Texas A&M University System; and Jolanda Prozzi, Center for Transportation Research, The University of Texas at Austin CENTER FOR TRANSPORTATION RESEARCH Bureau of Engineering Research

Texas at Austin, University of

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Photo Upload Photo Selection Guide  

E-Print Network [OSTI]

Photo Upload Photo Selection Guide It is important that your photo is suitable for use on your College Card so please ensure that you follow this guidance when selecting a photo to upload. Technical Requirements Photo height: Between 400 and 1280 pixels Photo width: Between 300 and 960

Royal Holloway, University of London

322

STRATEGY AND GUIDING Prepared for  

E-Print Network [OSTI]

Grid) o The Security Team including resources from Consumers Energy, EnerNex Corporation, In for the Smart Grid (ASAP-SG) in an effort to provide security guidelines for smart grid applications in how the documents fit together to improve smart grid security and the thinking that guided

323

Computed-tomographic-guided minithoracotomy  

SciTech Connect (OSTI)

A simple computed tomographic method, using precise surface localization, to locate small subpleural nodules or pulmonary lesions is described. This permits a guided minithoracotomy for chest lesions which are not visible on plain radiographs or are considered inaccessible by percutaneous or transbronchoscopic biopsy.

Daly, B.D.; Pugatch, R.D.; Faling, L.J.; Jung-Legg, Y.; Gale, M.E.; Snider, G.L.

1983-02-01T23:59:59.000Z

324

ADMINISTRATIVE GUIDE TO STUDENT ACCOUNTS  

E-Print Network [OSTI]

ADMINISTRATIVE GUIDE TO STUDENT ACCOUNTS UNIVERSITY CASHIER'S OFFICE 2005 Harris Hall 515-2986 http://www.fis-2985 Tuition Waivers ......................................................... 513-4264 Cashier's Office: http://www.fis.ncsu.edu/cashier/ Billing Calendars: http://www.fis.ncsu.edu/cashier/billing/billsched.asp Sponsored Students: http://www.fis

325

Geisel Library Self-Guided  

E-Print Network [OSTI]

Geisel Library Self-Guided Tour UC San Diego Libraries 9500 Gilman Drive #0175 La Jolla, CA 92093 modern libraries, the futuristic concrete and glass Geisel Library building was designed by world in as much natural light as is found on the upper floors. Welcome to UC San Diego's Geisel Library! This self

Tsien, Roger Y.

326

2009 coal preparation buyer's guide  

SciTech Connect (OSTI)

The guide contains brief descriptions and contact details of 926 US companies supplying coal preparation equipment who exhibited at the 26th annual Coal Prep exhibition and conference, 28-30 April - May 2009, in Lexington, KY, USA. An index of categories of equipment available from the manufacturers is included.

NONE

2009-04-15T23:59:59.000Z

327

Integrated Safety Management System Guide  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The guide provide DOE line management information useful for implementing the provisions of DOE P 450.4A and the requirements and responsibilities of DOE O 450.2. Cancels and supersedes DOE G 450.4-1B and DOE G 450.3-3.

2011-09-29T23:59:59.000Z

328

Document Supply Services Quick Guide  

E-Print Network [OSTI]

, phrase, ISBN/ISSN in the Search Term field (other options are available in the dropdown menu). Note1 Document Supply Services Quick Guide The DSS Portal makes requesting easy! Search for your item and password. If you are having difficulty please read the login help on the main DSS webpage. 2. Enter a word

329

Quickstart Guide | Open Energy Information  

Open Energy Info (EERE)

Quickstart Guide Quickstart Guide Jump to: navigation, search OpenEI.jpg Contents 1 OpenEI Quick-Start Guide 1.1 Creating and Editing OpenEI Pages 1.1.1 Core content policies 1.1.2 Creating an account 1.1.3 Creating and editing pages 1.1.4 Spanish-language page tracking 1.1.5 Help 1.1.6 OpenEI Discussion Group 1.2 Monitoring OpenEI Pages 1.2.1 Monitoring new pages and page changes 1.2.2 Managing a Wiki Watchlist 1.3 Participating in the OpenEI Community OpenEI Quick-Start Guide Creating and Editing OpenEI Pages Core content policies Before you begin creating or editing pages, please review the OpenEI core content policies. In brief, OpenEI content should meet the following guidelines: Neutral Point of View: Content added must give a neutral, unbiased viewpoint. Verifiability: Content must give attribution back to its source.

330

Mobile Device Guide Google Android based devices  

E-Print Network [OSTI]

Mobile Device Guide ­ Google Android based devices CSUF Date Last Revised: 1/20/11 Page 1 of 3;Mobile Device Guide ­ Google Android based devices CSUF Date Last Revised: 1/20/11 Page 2 of 3 2. Under' with your campus username and enter your password (case sensitive). 4. Tap `next'. #12;Mobile Device Guide

de Lijser, Peter

331

GUIDE FOR APPLICANTS COORDINATION AND SUPPORT ACTION  

E-Print Network [OSTI]

@epss-fp7.org IPR help desk http://www.ipr-helpdesk.org Ethics help desk http://cordis.europa.eu/fp7/get on Audit Certification Guide for beneficiaries Guide to Financial Issues · Guide to IPR · Checklist

De Cindio, Fiorella

332

"Enabling the Mission" A Practical Guide to  

E-Print Network [OSTI]

"Enabling the Mission" A Practical Guide to Federal Service Oriented Architecture Version 1.1 June Practical Guide to Federal Service Oriented Architecture The Federal CIO Council Architecture-SIG) Presents: A Practical Guide to Federal Service Oriented Architecture Version 1.1 - June 2008 June 30, 2008

333

AOC-by-self-discovery modeling and simulation for HIV  

Science Journals Connector (OSTI)

Among HIV, immune cell and drug, exhibit interactions that are usually not well understood and as a result, cannot be accurately modeled. In this paper, Modeling by AOC is to understand the dynamics of HIV infection and treatment. The use of AOC-by-self-discovery ...

Chunxiao Zhao; Ning Zhong; Ying Hao

2007-09-01T23:59:59.000Z

334

Iron chelators ICL670 and 311 inhibit HIV-1 transcription  

SciTech Connect (OSTI)

HIV-1 replication is induced by an excess of iron and iron chelation by desferrioxamine (DFO) inhibits viral replication by reducing proliferation of infected cells. Treatment of cells with DFO and 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone (311) inhibit expression of proteins that regulate cell-cycle progression, including cycle-dependent kinase 2 (CDK2). Our recent studies showed that CDK2 participates in HIV-1 transcription and viral replication suggesting that inhibition of CDK2 by iron chelators might also affect HIV-1 transcription. Here we evaluated the effect of a clinically approved orally effective iron chelator, 4-[3,5-bis-(hydroxyphenyl)-1,2,4-triazol-1-yl]-benzoic acid (ICL670) and 311 on HIV-1 transcription. Both ICL670 and 311 inhibited Tat-induced HIV-1 transcription in CEM-T cells, 293T and HeLa cells. Neither ICL670 nor 311 induced cytotoxicity at concentrations that inhibited HIV-1 transcription. The chelators decreased cellular activity of CDK2 and reduced HIV-1 Tat phosphorylation by CDK2. Neither ICL670A or 311 decreased CDK9 protein level but significantly reduced association of CDK9 with cyclin T1 and reduced phosphorylation of Ser-2 residues of RNA polymerase II C-terminal domain. In conclusion, our findings add to the evidence that iron chelators can inhibit HIV-1 transcription by deregulating CDK2 and CDK9. Further consideration should be given to the development of iron chelators for future anti-retroviral therapeutics.

Debebe, Zufan; Ammosova, Tatyana [Center for Sickle Cell Disease, Howard University College of Medicine, 520 W. St., N.W., Washington, DC 20060 (United States); Jerebtsova, Marina [Children's National Medical Center, CRI Center for Cancer and Immunology, 111 Michigan Ave., N.W., Washington, DC 20060 (United States); Kurantsin-Mills, Joseph [Department of Biophysics and Physiology, Howard University College of Medicine, 520 W. St., N.W., Washington, DC 20060 (United States); Niu, Xiaomei; Charles, Sharroya [Center for Sickle Cell Disease, Howard University College of Medicine, 520 W. St., N.W., Washington, DC 20060 (United States); Richardson, Des R. [Iron Metabolism and Chelation Program, Department of Pathology, Blackburn Building (D06), University of Sydney, Sydney, New South Wales, 2006 Australia (Australia); Ray, Patricio E. [Children's National Medical Center, CRI Center for Cancer and Immunology, 111 Michigan Ave., N.W., Washington, DC 20060 (United States); Gordeuk, Victor R. [Center for Sickle Cell Disease, Howard University College of Medicine, 520 W. St., N.W., Washington, DC 20060 (United States); Nekhai, Sergei [Center for Sickle Cell Disease, Howard University College of Medicine, 520 W. St., N.W., Washington, DC 20060 (United States); Department of Biochemistry and Molecular Biology, Howard University College of Medicine, 520 W. St., N.W., Washington, DC 20060 (United States)], E-mail: snekhai@howard.edu

2007-10-25T23:59:59.000Z

335

RESEARCH Open Access HIV-1 Tat protein binds to TLR4-MD2 and signals  

E-Print Network [OSTI]

RESEARCH Open Access HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF- and IL-10 Nawal in a TLR4 dependent manner. Conclusions: Collectively, our data showed for the first time that, HIV-1 Tat progression. Keywords: HIV-1, TLR4, Tat, IL-10, TNF- Background HIV-1 infects numerous cells of the immune

Boyer, Edmond

336

HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold  

E-Print Network [OSTI]

HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold Seemay for review October 2, 2012) The HIV-1 Tat protein stimulates viral gene expression by recruiting human genome, HIV infection is hypersensitive to elongation defects. The HIV-1 Tat protein recruits active P

Martin, Gail

337

Regulation of the Human Endogenous Retrovirus K (HML-2) Transcriptome by the HIV-1 Tat Protein  

Science Journals Connector (OSTI)

...HML-2) Transcriptome by the HIV-1 Tat Protein Marta J. Gonzalez-Hernandez...endogenous retroviral sequences. As the HIV-1 Tat protein activates the overall expression...with HIV-1, in part due to the HIV-1 Tat protein. The findings reported...

Marta J. Gonzalez-Hernandez; James D. Cavalcoli; Maureen A. Sartor; Rafael Contreras-Galindo; Fan Meng; Manhong Dai; Derek Dube; Anjan K. Saha; Scott D. Gitlin; Gilbert S. Omenn; Mark H. Kaplan; David M. Markovitz

2014-05-28T23:59:59.000Z

338

E-Print Network 3.0 - anti-pathology vaccine development Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

are vaccinated by January 14, 2011. The first of three drawings for an i... Pad will be held on Monday, November 22, 2010, so don't hesitate to be vaccinated. The earlier an...

339

School Nurses' Role as Opinion Leaders Regarding the HPV Vaccine for Youth  

E-Print Network [OSTI]

opinion leaders regarding the HPV vaccine. The purpose of this study was to: (1) explain how the Diffusion of Innovations (DOI) theory explains school nurses' roles as opinion leaders regarding the HPV vaccine; (2) document current literature regarding...

Rosen, Brittany Leigh

2013-06-17T23:59:59.000Z

340

Cancer Research UK eGMS Applicant Guide Cancer Research UK (eGMS) applicant guide June 2012 Page 1  

E-Print Network [OSTI]

Cancer Research UK eGMS Applicant Guide Cancer Research UK (eGMS) applicant guide June 2012 Page 1 2012 INTERNAL USER GUIDE A Guide to the Cancer Research UK electronic Grants Management System (e://egms.cancerresearchuk.org #12;Cancer Research UK eGMS Applicant Guide Cancer Research UK (eGMS) applicant guide June 2012 Page 2

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Turbine nozzle stage having thermocouple guide tube  

DOE Patents [OSTI]

A guide tube is fixed adjacent opposite ends in outer and inner covers of a nozzle stage segment. The guide tube is serpentine in shape between the outer and inner covers and extends through a nozzle vane. An insert is disposed in the nozzle vane and has apertures to accommodate serpentine portions of the guide tube. Cooling steam is also supplied through chambers of the insert on opposite sides of a central insert chamber containing the guide tube. The opposite ends of the guide tube are fixed to sleeves, in turn fixed to the outer and inner covers.

Schotsch, Margaret Jones (Greer, SC); Kirkpatrick, Francis Lawrence (late of Galway, NY); Lapine, Eric Michael (Northwood, NH)

2002-01-01T23:59:59.000Z

342

DOE interpretations Guide to OSH standards. Update to the Guide  

SciTech Connect (OSTI)

Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued its support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal interpretation letters written by OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

Not Available

1994-03-31T23:59:59.000Z

343

DOE interpretations Guide to OSH standards. Update to the Guide  

SciTech Connect (OSTI)

Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued it`s support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal in letter written by OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

Not Available

1994-03-31T23:59:59.000Z

344

DOE interpretations Guide to OSH standards. Update to the Guide  

SciTech Connect (OSTI)

Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued its support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal interpretation letters written OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

Not Available

1994-03-31T23:59:59.000Z

345

E-Print Network 3.0 - antifungal vaccine derived Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of vaccines, ... Source: Virginia Tech, Virginia Bioinformatics Institute, Influenze Outbreak Project Collection: Biology and Medicine ; Computer Technologies and Information...

346

E-Print Network 3.0 - ah1n1v influenza vaccine Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

vaccines (subunit and virosomes) incorporated in sugar glass can... for the production of stabilized influenza ... Source: Groningen, Rijksuniversiteit - Centre for...

347

E-Print Network 3.0 - attenuated vaccine development Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

to pathogenic... the population of vaccine regimens' considered. Preclinical ... Source: Gilbert, Peter - Fred Hutchinson Cancer Research Center & Department of Biostatistics,...

348

E-Print Network 3.0 - anthrax vaccines bridging Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

effectively to subsequent challenge. Vaccines Source: Starnbach, Michael - Department of Microbiology and Molecular Genetics, Harvard University Collection: Biology and Medicine...

349

HQ Leave Guide | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

HQ Leave Guide HQ Leave Guide HQ Leave Guide The purpose of this guide is to provide you, as a Headquarters employee, advice and guidance concerning issues related to hours of duty, time & attendance, and matters related to taking time off (e.g., annual and sick leave). However, this guide can not provide all encompassing guidance for all situations. In many cases, the answer is subject to office policy and/or supervisory judgment. For these reasons, any questions about how matters in this guide apply to you should first be discussed with your supervisor. HQ Leave Guide Responsible Contacts Myron Alston Human Resources Specialist (Labor & Employee Relations) E-mail myron.alston@hq.doe.gov Phone 202-586-8734 More Documents & Publications DOE Handbook on Leave and Absence

350

Advanced Energy Retrofit Guides | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Retrofit Guides Retrofit Guides Advanced Energy Retrofit Guides Photo of the cover of the Advanced Energy Retrofit Guide for Healthcare Facilities. The Advanced Energy Retrofit Guides (AERGs) were created to help decision makers plan, design, and implement energy improvement projects in their facilities. With energy managers in mind, they present practical guidance for kick-starting the process and maintaining momentum throughout the project life cycle. These guides are primarily reference documents, allowing energy managers to consult the particular sections that address the most pertinent topics.. Useful resources are also cited throughout the guides for further information. Each AERG is tailored specifically to the needs of a specific building type, with an emphasis on the most effective

351

Co-infecção HIV-1/Tripanossomatídeos em macrófagos humanos: efeito da infecção pelo HIV-1 e da proteína Tat do HIV-1 sobre a replicação parasitária.  

E-Print Network [OSTI]

??Protozoários parasitos aparecem como co-patógenos em infecções pelo vírus da imunodeficiência humana (HIV)-1, resultando em um aumento mútuo na replicação viral e parasitária, e facilitando… (more)

Victor Barreto de Souza Brasil Silva

2009-01-01T23:59:59.000Z

352

Solar Ready Buildings Planning Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

78 78 December 2009 Solar Ready Buildings Planning Guide L. Lisell, T. Tetreault, and A. Watson National Renewable Energy Laboratory 1617 Cole Boulevard, Golden, Colorado 80401-3393 303-275-3000 * www.nrel.gov NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency and Renewable Energy Operated by the Alliance for Sustainable Energy, LLC Contract No. DE-AC36-08-GO28308 Technical Report NREL/TP-7A2-46078 December 2009 Solar Ready Buildings Planning Guide L. Lisell, T. Tetreault, and A. Watson Prepared under Task No. PVC9.92DA NOTICE This report was prepared as an account of work sponsored by an agency of the United States government. Neither the United States government nor any agency thereof, nor any of their employees, makes any

353

Solar Ready Buildings Planning Guide  

Broader source: Energy.gov (indexed) [DOE]

6078 6078 December 2009 Solar Ready Buildings Planning Guide L. Lisell, T. Tetreault, and A. Watson National Renewable Energy Laboratory 1617 Cole Boulevard, Golden, Colorado 80401-3393 303-275-3000 * www.nrel.gov NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency and Renewable Energy Operated by the Alliance for Sustainable Energy, LLC Contract No. DE-AC36-08-GO28308 Technical Report NREL/TP-7A2-46078 December 2009 Solar Ready Buildings Planning Guide L. Lisell, T. Tetreault, and A. Watson Prepared under Task No. PVC9.92DA NOTICE This report was prepared as an account of work sponsored by an agency of the United States government. Neither the United States government nor any agency thereof, nor any of their employees, makes any

354

Facility Representative Program: Surveillance Guides  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Assessment Tools Assessment Tools CRADs Manager's Guide for Safety and Health Walkthroughs Surveillance Guides CMS 3.1 Configuration Management Implementation CMS 3.2 Change Control CMS 3.3 Verification of System Configuration and Operations CMS 3.4 Temporary Changes CPS 8.1 Hoisting and Rigging CPS 8.2 Trenching and Excavation EMS 21.1 Emergency Preparedness ENS 7.1 Definition of Design Requirements ERS 14.1 Satellite Accumulation Ares (RCRA Compliance) ERS 14.2 Emmissions Monitoring ERS 14.3 Underground and Above Ground Diesel Fuel Storage Tanks FPS 12.1 Life Safety FPS 12.2 Fire Protection and Prevention MAS 10.1 Maintenance Activities MAS 10.2 Control of Measuring and Test Equipment MAS 10.3 Seasonal Preparation MSS 1.1 Corrective Action/Issue Management NSS 18.1 Criticality Safety

355

Energy Efficiency Best Practice Guide©  

E-Print Network [OSTI]

capital and maintenance expenditure through the identification and elimination of oversized or redundant equipment. Unlike other disciplines, energy efficiency is usually not measured at the business unit level. The difficulty is that energy use... of the Energy Efficiency Best Practice Guide is to help business units meet and exceed their energy efficiency targets through continuous improvement using seven key criteria. The objectives are threefold: to provide an easy to use structure for measuring...

Rouse, S.

356

Video through a light guide  

Science Journals Connector (OSTI)

Demonstrations are discussed to illustrate some basic principles of television transmission and reception. The aim of these demonstrations is to promote student understanding of how a picture is converted into an electrical signal sent to a remote receiver and correctly reproduced there. The demonstration setup includes a video camera a light emitting diode a light guide a photodiode and a video monitor. Electrical production of visual images is also discussed.

Yaakov Kraftmakher

2008-01-01T23:59:59.000Z

357

Regulatory facility guide for Ohio  

SciTech Connect (OSTI)

The Regulatory Facility Guide (RFG) has been developed for the DOE and contractor facilities located in the state of Ohio. It provides detailed compilations of international, federal, and state transportation-related regulations applicable to shipments originating at destined to Ohio facilities. This RFG was developed as an additional resource tool for use both by traffic managers who must ensure that transportation operations are in full compliance with all applicable regulatory requirements and by oversight personnel who must verify compliance activities.

Anderson, S.S.; Bock, R.E.; Francis, M.W.; Gove, R.M.; Johnson, P.E.; Kovac, F.M.; Mynatt, J.O. [Oak Ridge National Lab., TN (United States); Rymer, A.C. [Transportation Consulting Services, Knoxville, TN (United States)

1994-02-28T23:59:59.000Z

358

REC Tracking Systems Design Guide  

SciTech Connect (OSTI)

OAK-B135 The Design Guide is presented in three parts. Section II describes the need for REC tracking, the two principal tracking methods available, and, in simple terms, the operation of certificate-based systems. Section III presents the major issues in the design of certificate-based tracking systems and discusses the advantages and disadvantages of alternative solutions. Finally, Section IV offers design principles or recommendations for most of these issues.

Meredith Wingate

2004-02-03T23:59:59.000Z

359

Cavitation guide for control valves  

SciTech Connect (OSTI)

This guide teaches the basic fundamentals of cavitation to provide the reader with an understanding of what causes cavitation, when it occurs, and the potential problems cavitation can cause to a valve and piping system. The document provides guidelines for understanding how to reduce the cavitation and/or select control valves for a cavitating system. The guide provides a method for predicting the cavitation intensity of control valves, and how the effect of cavitation on a system will vary with valve type, valve function, valve size, operating pressure, duration of operation and details of the piping installation. The guide defines six cavitation limits identifying cavitation intensities ranging from inception to the maximum intensity possible. The intensity of the cavitation at each limit Is described, including a brief discussion of how each level of cavitation influences the valve and system. Examples are included to demonstrate how to apply the method, including making both size and pressure scale effects corrections. Methods of controlling cavitation are discussed providing information on various techniques which can be used to design a new system or modify an existing one so it can operate at a desired level of cavitation.

Tullis, J.P. [Tullis Engineering Consultants, Logan, UT (United States)

1993-04-01T23:59:59.000Z

360

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator  

SciTech Connect (OSTI)

An important point of regulation in the reproductive growth and latency of the human and simian immunodeficiency viruses (HIV and SIV, respectively) is provided by virally encoded trans-activators (tat), proteins capable of dramatically increasing viral gene expression. The mechanism of this autostimulatory pathway has remained unclear, however, with substantial effects having been reported at the level of either mRNA accumulation, translational efficiency, or both. The authors' previous findings indicated that trans-activation results primarily from induction of RNA levels but could not distinguish between the roles of transcriptional rate, RNA stabilization, and RNA transport in this event. In addition, the boundaries of tat-responding elements, which would be valuable in elucidating the mode of tat action, are not precisely known. In this study, HIV-1 and HIV-2 long terminal repeat-directed expression was characterized by using in an vitro nuclear transcription assay to clarify this mechanism, and a detailed mutational analysis was undertaken to localize precisely the sequences participating in this process. Two key findings were revealed: an increased transcription rate was the primary event in tat-mediated activation of HIV-1 and HIV-2, and trans-activation was impaired by mutations in two regions, the TATA box and sequences between +19 to +42, a region lacking enhancer activity. These results implicate a discrete 3' regulatory element in the transcriptional activation of the HIVs.

Jakobovits, A.; Smith, D.H.; Jakobovits, E.B.; Capon, D.J.

1988-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Computer analysis of HIV epitope sequences  

SciTech Connect (OSTI)

Phylogenetic tree analysis provide us with important general information regarding the extent and rate of HIV variation. Currently we are attempting to extend computer analysis and modeling to the V3 loop of the type 2 virus and its simian homologues, especially in light of the prominent role the latter will play in animal model studies. Moreover, it might be possible to attack the slightly similar V4 loop by this approach. However, the strategy relies very heavily upon natural'' information and constraints, thus there exist severe limitations upon the general applicability, in addition to uncertainties with regard to long-range residue interactions. 5 refs., 3 figs.

Gupta, G.; Myers, G.

1990-01-01T23:59:59.000Z

362

Effectiveness of Pneumococcal Polysaccharide Vaccine in Older Adults  

Science Journals Connector (OSTI)

...years of age or older. Methods. Study Cohort. The study population consisted of members of the Group Health Cooperative, a health maintenance organization (HMO) in Washington State, who were at least 65 years of age on March 1, 1998 (the date of the start of the study) and who had been enrolled for... This population-based, retrospective study of more than 47,000 older persons assessed the effectiveness of pneumococcal vaccination. Vaccination was associated with a significant reduction in the risk of pneumococcal bacteremia, but over three years of follow-up there was no reduction in the risk of community-acquired pneumonia (hazard ratio, 1.07).

Jackson L.A.; Neuzil K.M.; Yu O.

2003-05-01T23:59:59.000Z

363

Priming after a Fractional Dose of Inactivated Poliovirus Vaccine  

Science Journals Connector (OSTI)

...each vaccination, the infants were monitored for 60 minutes for immediate adverse events and were also evaluated by qualified medical staff during home visits at 24 and 48 hours. Adverse events were classified as minor, moderate, or severe in intensity and as serious or not serious in consequence. No... Post-polio eradication planning is under way. In this randomized trial, a fractional dose (one fifth) of the inactivated polio vaccine given intradermally in 4-month-old infants in Cuba induced priming and seroconversion in more than 90% of infants.

Resik S.; Tejeda A.; Sutter R.W.

2013-01-31T23:59:59.000Z

364

HIV-1 Tat C-mediated regulation of tumor necrosis factor receptor-associated factor-3 by microRNA 32 in human microglia  

Science Journals Connector (OSTI)

HIV-1 Tat protein is known to be associated with ... develops in almost half of patients infected with HIV-1. HIV-1 Tat can alter glial neuroprotective functions, leading to neurotoxicity within the CNS. HIV-1 Tat

Ritu Mishra; Chintan Chhatbar; Sunit Kumar Singh

2012-06-01T23:59:59.000Z

365

Health Care Provider Attitudes and Beliefs About People Living with HIV: Initial Validation of the Health Care Provider HIV/AIDS Stigma Scale (HPASS)  

Science Journals Connector (OSTI)

HIV stigma is a pressing concern for people living with HIV, and particularly when it is perpetuated by health care providers, as it may affect quality of life and access to health care services. The current s...

Anne C. Wagner; Trevor A. Hart; Kelly E. McShane; Shari Margolese…

2014-12-01T23:59:59.000Z

366

Effects of protein or zinc deficiency on cellular immunity in vaccinated and non-vaccinated guinea pigs with experimentally induced pulmonary listeriosis  

E-Print Network [OSTI]

EFFECTS OF PROTEIN OR ZINC DEFICIENCY ON CELLULAR IMMUNITY IN VACCINATED AND NON-VACCINATED GUINEA PIGS WITH EXPERIMENTALLY INDUCED PULMONARY LISTERIOS I 8 A Thesi s by LEZLEE HELAINE GRAHAM COGHLAN Submitted to the Graduate College of Texas... animals were vaccinated on day 23, and all received aerosol challenge on day 33 and were killed 4 days later. Both zinc and protein deficiency resulted in animals that were clinically abnormal in growth patterns, hematology, ability to mount a delayed...

Coghlan, Lezlee Helaine Graham

1984-01-01T23:59:59.000Z

367

Electron Beam As A Next Generation Vaccine Platform: Microbiological And Immunological Characterization Of An Electron Beam Based Vaccine Against Salmonella Typhimurium  

E-Print Network [OSTI]

of Salmonella are currently being considered as live vaccine candidates as they are capable of inducing humoral as well as cellular immune responses (Mittrucker et al., 2000). Studies have revealed that live vaccines are more effective than killed or non-replicating... is “attenuated” or “weakened” by different methods which reduces its ability to cause disease, but retains the ability to replicate and produce immune response (CDC, 2012). There are different approaches used for generating live attenuated vaccines. One...

Praveen, Chandni

2014-04-16T23:59:59.000Z

368

PEPFAR in Transition — Implications for HIV Care in South Africa  

Science Journals Connector (OSTI)

...anniversary of the creation of the President's Emergency Plan for AIDS Relief (PEPFAR), widely considered the most ambitious and successful global public health program since smallpox eradication. Over the past decade, PEPFAR has funded HIV–AIDS treatment for more than 5 million people in resource-limited... With the U.S. government halving the budget for the President's Emergency Plan for AIDS Relief in South Africa by 2017, the country is transitioning to full ownership of its HIV program. Will the move jeopardize the health of 1.7 million South Africans being treated for HIV?

Katz I.T.Bassett I.V.Wright A.A.

2013-10-10T23:59:59.000Z

369

Manager's Guide for Safety and Health Walkthroughs  

Broader source: Energy.gov (indexed) [DOE]

Manager's Guide Manager's Guide for Safety and Health Walkthroughs Page 2 of 23 ABOUT THIS GUIDE This Guide can serve as a tool in observing activities and conducting interviews of personnel during the walkthroughs. This Guide contains both general and discipline specific "lines of inquiry" for areas of safety and health. It is intended to act as a guide in promoting discussions with workers on various safety and health issues as well as to initiate a more focused observation of activities and conditions on site. The "Lines of Inquiry" are based on requirements and guidelines from a variety of references such as: Department of Energy Orders Department of Energy Standards Department of Energy Radiological Control Manual Code of Federal Regulations, Title 29, Part 1910, Occupational

370

Cell, Vol. 122, 147155, July 29, 2005, Copyright 2005 by Elsevier Inc. of HIV-1. Their aim was to determine whether HIV-1 lat-  

E-Print Network [OSTI]

Adams and the physiologically low levels of Tat expression upon initial entry of HIV-1 into the host cell. In the model, lowCell, Vol. 122, 147­155, July 29, 2005, Copyright ©2005 by Elsevier Inc. Previews of HIV-1. Their aim was to determine whether HIV-1 lat- And the Noise Played On: ency can be explained

Collins, James J.

371

Tat Protein Induces Human Immunodeficiency Virus Type 1 (HIV-1) Coreceptors and Promotes Infection with both Macrophage-Tropic and T-Lymphotropic HIV-1 Strains  

Science Journals Connector (OSTI)

...respectively. Here we demonstrate that HIV-1 Tat protein, a potent viral transactivator...results define a novel role for Tat in HIV-1 pathogenesis that promotes the...immunodeficiency virus type 1 (HIV-1) Tat protein, a potent viral transactivator...

Lili Huang; Irene Bosch; Wolfgang Hofmann; Joseph Sodroski; Arthur B. Pardee

1998-11-01T23:59:59.000Z

372

Children Are the Wealth of the Poor: Prevention of Mother-to-Child Transmission of HIV in Haiti  

E-Print Network [OSTI]

At roughly two percent, Haiti has one of the highest HIV prevalence rates in the Caribbean. This thesis examines HIV transmission in Haiti, specifically the transmission of HIV from mother to child during pregnancy, labor, ...

Denney, Rachel

2012-08-31T23:59:59.000Z

373

Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes and Transfer to TAR RNA  

Science Journals Connector (OSTI)

...Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes...bacteriophage lambda N protein, c-Myc, and HIV Tat (14, 16, 60, 84, 86). Studies of HIV Tat, which regulates elongation of the...

Iván D'Orso; Gwendolyn M. Jang; Alexander W. Pastuszak; Tyler B. Faust; Elizabeth Quezada; David S. Booth; Alan D. Frankel

2012-09-24T23:59:59.000Z

374

HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study  

Science Journals Connector (OSTI)

How HIV-1 enter into the eyes remains obscure. We postulated that HIV-1 Tat protein can alter the expression of specific ... the blood retinal barrier, and contributes to HIV trafficking into the eyes. This study...

Ling Bai; Zhenping Zhang; Hui Zhang; Xiumei Li; Qiurong Yu…

2008-06-01T23:59:59.000Z

375

Transfer Guide: Philosophy: General Philosophy Concentration Revised: 1 December 2009 TRANSFER GUIDE AND PLANNING WORKSHEET  

E-Print Network [OSTI]

Transfer Guide: Philosophy: General Philosophy Concentration Revised: 1 December 2009 TRANSFER Degree ­ Philosophy general philosophy concentration This planning worksheet represents a guide for community college students transferring to Colorado State University and majoring in Philosophy: general

376

Guide to good practices for communications  

SciTech Connect (OSTI)

The purpose of this Guide to Good Practices is to provide Department of Energy (DOE) contractors with information that can be used to validate and/or modify existing programs relative to Conduct of Operations. This Guide to Good Practices is part of a series of guides designed to enhance the guidelines set forth in DOE Order 5480.19, Conduct of Operations Requirements for DOE Facilities.''

Not Available

1992-12-01T23:59:59.000Z

377

Guide to good practices for logkeeping  

SciTech Connect (OSTI)

The purpose of this Guide to Good Practices is to provide Department of Energy (DOE) contractors with information that can be used to validate and/or modify existing programs relative to Conduct of Operations. This Guide to Good Practices is part of a series of guides designed to enhance the guidelines set forth in DOE Order 5480. 19, ``Conduct of Operations Requirement for DOE Facilities.`` (JDB)

Not Available

1993-03-01T23:59:59.000Z

378

Guide to good practices for logkeeping  

SciTech Connect (OSTI)

The purpose of this Guide to Good Practices is to provide Department of Energy (DOE) contractors with information that can be used to validate and/or modify existing programs relative to Conduct of Operations. This Guide to Good Practices is part of a series of guides designed to enhance the guidelines set forth in DOE Order 5480. 19, Conduct of Operations Requirement for DOE Facilities.'' (JDB)

Not Available

1993-03-01T23:59:59.000Z

379

Guide to good practices for communications  

SciTech Connect (OSTI)

The purpose of this Guide to Good Practices is to provide Department of Energy (DOE) contractors with information that can be used to validate and/or modify existing programs relative to Conduct of Operations. This Guide to Good Practices is part of a series of guides designed to enhance the guidelines set forth in DOE Order 5480.19, ``Conduct of Operations Requirements for DOE Facilities.``

Not Available

1992-12-01T23:59:59.000Z

380

Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics  

Science Journals Connector (OSTI)

Following CD4 receptor binding to the HIV-1 envelope spike (Env), the conserved N-heptad repeat (NHR) region of gp41 forms a coiled-coil that is a precursor to the fusion reaction. Although it has been a target of drug and vaccine design, there are few monoclonal antibody (mAb) tools with which to probe the antigenicity and immunogenicity specifically of the NHR coiled-coil. Here, we have rescued HIV-1-neutralizing anti-NHR mAbs from immune phage display libraries that were prepared (i) from b9 rabbits immunized with a previously described mimetic of the NHR coiled-coil, N35CCG-N13, and (ii) from an HIV-1 infected individual. We describe a rabbit single-chain Fv fragment (scFv), 8K8, and a human Fab, DN9, which specifically recognize NHR coiled-coils that are unoccupied by peptide corresponding to the C-heptad repeat or CHR region of gp41 (e.g. C34). The epitopes of 8K8 and DN9 were found to partially overlap with that of a previously described anti-NHR mAb, IgG D5; however, 8K8 and DN9 were much more specific than D5 for unoccupied NHR trimers. The mAbs, including a whole IgG 8K8 molecule, neutralized primary HIV-1 of clades B and C in a pseudotyped virus assay with comparable, albeit relatively modest potency. Finally, a human Fab T3 and a rabbit serum (both non-neutralizing) were able to block binding of D5 and 8K8 to a gp41 NHR mimetic, respectively, but not the neutralizing activity of these mAbs. We conclude from these results that NHR coiled-coil analogs of HIV-1 gp41 elicit many Abs during natural infection and through immunization, but that due to limited accessibility to the corresponding region on fusogenic gp41 few can neutralize. Caution is therefore required in targeting the NHR for vaccine design. Nevertheless, the mAb panel may be useful as tools for elucidating access restrictions to the NHR of gp41 and in designing potential improvements to mimetics of receptor-activated Env.

Josh D. Nelson; Heather Kinkead; Florence M. Brunel; Dan Leaman; Richard Jensen; John M. Louis; Toshiaki Maruyama; Carole A. Bewley; Katherine Bowdish; G. Marius Clore; Philip E. Dawson; Shana Frederickson; Rose G. Mage; Douglas D. Richman; Dennis R. Burton; Michael B. Zwick

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

1  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Antibody evolution could guide HIV Antibody evolution could guide HIV vaccine development April 4, 2013 LOS ALAMOS, N. M., April 4, 2013-Observing the evolution of a particular type of antibody in an infected HIV-1 patient, a study spearheaded by Duke University, including analysis from Los Alamos National Laboratory, has provided insights that will enable vaccination strategies that mimic the actual antibody development within the body. The kind of antibody studied is called a broadly cross-reactive neutralizing antibody, and details of its generation could provide a blueprint for effective vaccination, according to the study's authors. In a paper published online in Nature this week, the team reported on the isolation, evolution and structure of a broadly neutralizing antibody from an

382

EMERGENCY MANAGEMENT QUALIFICATION STANDARD REFERENCE GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Emergency Emergency Management Qualification Standard Reference Guide JUNE 2009 Table of Contents i LIST OF FIGURES ...................................................................................................................... ii LIST OF TABLES ........................................................................................................................ ii ACRONYMS .................................................................................................................................. i PURPOSE...................................................................................................................................... 1 SCOPE ...........................................................................................................................................

383

FACILITY MAINTENANCE MANAGEMENT QUALIFICATION STANDARD REFERENCE GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Facility Facility Maintenance Management Qualification Standard Reference Guide NOVEMBER 2009 Table of Contents i FIGURES...................................................................................................................................... iv TABLES........................................................................................................................................ iv ACRONYMS ................................................................................................................................. v PURPOSE...................................................................................................................................... 1 SCOPE ...........................................................................................................................................

384

ENVIRONMENTAL COMPLIANCE QUALIFICATION STANDARD REFERENCE GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Environmental Environmental Compliance Qualification Standard Reference Guide DECEMBER 2011 Table of Contents i LIST OF FIGURES ..................................................................................................................... iii LIST OF TABLES ....................................................................................................................... iii ACRONYMS ................................................................................................................................ iv PURPOSE ...................................................................................................................................... 1 SCOPE ........................................................................................................................................... 1

385

ENVIRONMENTAL RESTORATION QUALIFICATION STANDARD REFERENCE GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Restoration Qualification Standard Reference Guide NOVEMBER 2009 i Table of Contents i FIGURES...................................................................................................................................... iv TABLES........................................................................................................................................ iv ACRONYMS ................................................................................................................................. v PURPOSE...................................................................................................................................... 1 SCOPE ...........................................................................................................................................

386

CRITICALITY SAFETY QUALIFICATION STANDARD REFERENCE GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Criticality Criticality Safety Qualification Standard Reference Guide APRIL 2011 This page is intentionally blank. Table of Contents i FIGURES ...................................................................................................................................... iii PURPOSE ...................................................................................................................................... 1 SCOPE ........................................................................................................................................... 1 PREFACE ...................................................................................................................................... 1 ACKNOWLEDGEMENTS ......................................................................................................... 2

387

FAQS Reference Guide – Safeguards and Security  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the May 2009 edition of DOE-STD-1171-2009, Safeguards and Security Functional Area Qualification Standard.

388

FAQS Reference Guide – Technical Program Manager  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the February 2004 edition of DOE-STD-1178-2004, Technical Program Manager Functional Area Qualification Standard.

389

EERE Program Management Guide- Appendix O  

Office of Energy Efficiency and Renewable Energy (EERE)

Appendix O provides a comprehensive list of acronyms for the different EERE programs/program offices, terms, facilities, procedures, and processes discussed throughout the guide.

390

Service Center Evaluation Guide | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Evaluation Guide (November 1999) More Documents & Publications Selected Bibliography on Electric Motor Repair Motor Repair Tech Brief Model Repair Specifications for Low Voltage...

391

Water Management Guide- Building America Top Innovation  

Broader source: Energy.gov [DOE]

This Top Innovation highlights the DOE-sponsored Water Management Guide, which has proven to be a highly effective tool for disseminating much needed best practices.

392

FAQS Reference Guide – NNSA Package Certification Engineer  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the February 2009 edition of DOE-STD-1026-2009, NNSA Package Certification Engineer Functional Area Qualification Standard.

393

EERE Program Management Guide- Chapter 2  

Office of Energy Efficiency and Renewable Energy (EERE)

Chapter 2 of this guide provides information on EERE programs and subprograms, roles and responsibilities, program management, and strategic management systems.

394

User Guides | Argonne Leadership Computing Facility  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

MiraCetusVesta Tukey Policies Documentation Feedback Please provide feedback to help guide us as we continue to build documentation for our new computing resource. Feedback...

395

FAQS Reference Guide – General Technical Base  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the December 2007 edition of DOE-STD-1146-2007, General Technical Base Functional Area Qualification Standard.

396

FAQS Reference Guide – Facility Maintenance Management  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the April 2014 edition of DOE Standard DOE-STD-1181-2014, Facility Maintenance Management Functional Area Qualification Standard.

397

Advanced Energy Retrofit Guide Retail Buildings  

SciTech Connect (OSTI)

The Advanced Energy Retrofit Guide for Retail Buildings is a component of the Department of Energy’s Advanced Energy Retrofit Guides for Existing Buildings series. The aim of the guides is to facilitate a rapid escalation in the number of energy efficiency projects in existing buildings and to enhance the quality and depth of those projects. By presenting general project planning guidance as well as financial payback metrics for the most common energy efficiency measures, these guides provide a practical roadmap to effectively planning and implementing performance improvements for existing buildings.

Liu, Guopeng; Liu, Bing; Zhang, Jian; Wang, Weimin; Athalye, Rahul A.; Moser, Dave; Crowe, Eliot; Bengtson, Nick; Effinger, Mark; Webster, Lia; Hatten, Mike

2011-09-19T23:59:59.000Z

398

Summer Research Project Guide 2010 Calendar  

E-Print Network [OSTI]

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12/02/09 SRP Guide Available Online on SRP website prior to check release) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7/05/10 Research Seminar #4: Preparing your SRP Presentation

Das, Soma

399

FAQS Reference Guide – Transportation and Traffic Management  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the September 2002 edition of DOE-STD-1155-2002, Transportation and Traffic Functional Area Qualification Standard.

400

Experiment Design and Analysis Guide - Neutronics & Physics  

SciTech Connect (OSTI)

The purpose of this guide is to provide a consistent, standardized approach to performing neutronics/physics analysis for experiments inserted into the Advanced Test Reactor (ATR). This document provides neutronics/physics analysis guidance to support experiment design and analysis needs for experiments irradiated in the ATR. This guide addresses neutronics/physics analysis in support of experiment design, experiment safety, and experiment program objectives and goals. The intent of this guide is to provide a standardized approach for performing typical neutronics/physics analyses. Deviation from this guide is allowed provided that neutronics/physics analysis details are properly documented in an analysis report.

Misti A Lillo

2014-06-01T23:59:59.000Z

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Guide on Federal Employee Assistance Programs  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

This Guide supplements the requirements and responsibilities specified in DOE O 341.1A. Cancels DOE G 341.1-2.

2007-10-18T23:59:59.000Z

402

Advanced Energy Design Guides | Department of Energy  

Energy Savers [EERE]

& Publications Advanced Energy Guides State and Local Code Implementation: Southwest Region - 2014 BTO Peer Review Multi-Year Program Plan, Building Regulatory Programs: 2010-2015...

403

GIS DEVELOPMENT GUIDE Table of Contents  

E-Print Network [OSTI]

GIS DEVELOPMENT GUIDE Volume II Table of Contents SURVEY OF AVAILABLE DATA Introduction ...................................................................................13 EVALUATING GIS HARDWARE AND SOFTWARE Introduction ...................................................................................14 Sources of Information About GIS......................................................14 GIS

Ghelli, Giorgio

404

2009 Industry-Wide Buyer's Guide  

SciTech Connect (OSTI)

The guide lists US companies supplying equipment and services to coal mining and coal preparation operations. An index by product category is included.

NONE

2009-10-15T23:59:59.000Z

405

EERE Program Management Guide- Chapter 6  

Office of Energy Efficiency and Renewable Energy (EERE)

Chapter 6 of this guide includes general concepts on program implementation such as identifying work to be performed, field input, funding work, and procurement, and financial assistance.

406

Guide to Financing EnergySmart Schools  

Office of Energy Efficiency and Renewable Energy (EERE)

This guide addresses barriers to and methods of financing energy-efficient schools, and makes a business case for high-performance design.

407

FAQS Reference Guide – Weapon Quality Assurance  

Broader source: Energy.gov [DOE]

This reference guide addresses the competency statements in the August 2008 edition of DOE-STD-1025-2008, Weapon Quality Assurance Functional Area Qualification Standard.

408

Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV  

Science Journals Connector (OSTI)

In 2008, 25 years after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti-HIV compounds have been formally approved for clinical use in the treatment of AIDS. These compounds fall into six categories: nucleoside reverse transcriptase inhibitors (NRTIs: zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine); nucleotide reverse transcriptase inhibitors (NtRTIs: tenofovir); non-nucleoside reverse transcriptase inhibitors (NNRTIs: nevirapine, delavirdine, efavirenz and etravirine); protease inhibitors (PIs: saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir); cell entry inhibitors [fusion inhibitors (FIs: enfuvirtide) and co-receptor inhibitors (CRIs: maraviroc)]; and integrase inhibitors (INIs: raltegravir). These compounds should be used in drug combination regimens to achieve the highest possible benefit, tolerability and compliance and to diminish the risk of resistance development.

Erik De Clercq

2009-01-01T23:59:59.000Z

409

Factors Predicting Completion of the Human Papillomavirus Vaccine Series  

Science Journals Connector (OSTI)

Purpose This study identified factors associated with completion of the three dose quadrivalent human papillomavirus vaccine (HPV4) series by female adolescents. Methods Between February and September 2008, we prospectively surveyed 11- to 26-year-old female members of an integrated managed care organization shortly after their first HPV4 dose to identify factors that predicted series completion. We used regression analyses to assess whether self-reported experiences at the index visit, knowledge/attitudes about HPV and HPV4, and medical record data on adverse events, demographic characteristics, care-utilization frequency, and visit characteristics, were associated with vaccine series completion within one year of the first HPV4 dose. Results Of 899 survey respondents (27% of 3347 survey recipients), 786 (87%) maintained continuous enrollment in the health plan in the year following the first HPV4 dose. Fifty percent (n = 393) completed the vaccine series within that year. In multivariate analyses of survey respondents, only respondents’ ability to correctly identify the number of shots required for series completion was significantly associated with series completion. Reported bruising was associated with decreased likelihood of completion, and the clinician stating that future shots were required was associated with increased likelihood, but both were of borderline significance. Females ages 16–20 had the lowest series completion. Conclusions Improving HPV4 completion will require targeted efforts. Our results suggest that providers may help by stressing the need for additional doses of vaccine, and confirming that patients understand this information. Special attention should be given to females ages 16–20. Future randomized trials should assess the effect on vaccine completion of these simple, low-cost interventions.

Rachel Gold; Allison Naleway; Karen Riedlinger

2013-01-01T23:59:59.000Z

410

LANL researchers use computer modeling to study HIV | National Nuclear  

National Nuclear Security Administration (NNSA)

researchers use computer modeling to study HIV | National Nuclear researchers use computer modeling to study HIV | National Nuclear Security Administration Our Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Continuing Management Reform Countering Nuclear Terrorism About Us Our Programs Our History Who We Are Our Leadership Our Locations Budget Our Operations Media Room Congressional Testimony Fact Sheets Newsletters Press Releases Speeches Events Social Media Video Gallery Photo Gallery NNSA Archive Federal Employment Apply for Our Jobs Our Jobs Working at NNSA Blog Home > NNSA Blog > LANL researchers use computer modeling to study HIV LANL researchers use computer modeling to study HIV Posted By Office of Public Affairs Los Alamos National Laboratory researchers are investigating the complex

411

Fragment Screen against HIV Protease: Discovery of Two Allosteric...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Y., Moisi, D., Oliveira, M., Turner, D., Wainberg, M. A. & co-investigators of the Quebec Primary Infection Study. (2004) Persistence of multidrug-resistant HIV-1 in primary...

412

Additivity in the Analysis and Design of HIV Protease Inhibitors  

E-Print Network [OSTI]

We explore the applicability of an additive treatment of substituent effects to the analysis and design of HIV protease inhibitors. Affinity data for a set of inhibitors with a common chemical framework were analyzed to ...

Jorissen, Robert N.

413

Decision making in the HIV/AIDS supply chain  

E-Print Network [OSTI]

During the first two decades of HIV/AIDS awareness, the U.S. and foreign governments responded slowly to the crisis. In contrast today, as the pandemic continues, initiatives of nonprofit organizations have dramatically ...

Cao, Elaine Phu

2007-01-01T23:59:59.000Z

414

Emerging nanotechnology approaches for HIV/AIDS treatment and prevention  

E-Print Network [OSTI]

Emerging nanotechnology approaches for HIV/AIDS treatment and prevention The emergence of AIDS effects and is ineffective in patients in whom the virus develops resistance. Nanotechnology of nanotechnology to provide more effective treatment and preven

von Andrian, Ulrich H.

415

Essays on HIV/AIDS in sub-Saharan Africa  

E-Print Network [OSTI]

HIV-1 Prenvetion SErvices in Dar Es Salaam, Tanzania: Thein Nairobi, Kenya and Dar Es Salaam, Tanzania. ” In bothurban Kenya (13-14%) and Dar es Salaam, Tanzania (10-12%) (

Gong, Erick Joseph

2011-01-01T23:59:59.000Z

416

Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

LIBXSIF, LIBXSIF, a Library for Parsing the Extended Standard Input Format of Accelerator Beamlines P. Tenenbaum LCC-Note-0060 14-Jun-2001 Abstract We describe LIBXSIF, a standalone library for parsing the Extended Standard Input Format of accelerator beamlines. Included in the description are: documentation of user commands; full description of permitted accelerator elements and their attributes; the construction of beamline lists; the mechanics of adding LIBXSIF to an existing program; and "under the hood" details for users who wish to modify the library or are merely morbidly curious. Contents 1 Version Information 3 2 Introduction 3 3 General Syntax 4 3.1 More on Names . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.2 Named Parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.3 Elements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.4 Beamlines . . . . . .

417

Unraveling the paradoxes of HIV-associated psoriasis: A review of T-cell subsets and cytokine profiles  

E-Print Network [OSTI]

8. PubMed 28. Mallon E, Bunker CB. HIV-associated psoriasis.Easterbrook PJ, Newson R, Bunker CB. HLA-Cw*0602 and HIV-

Fife, Douglas J; Waller, Jeanette M; Jeffes, Edward W; Koo, John YM

2007-01-01T23:59:59.000Z

418

Mother- to - Child Transmission of HIV and congenital syphilis: A snapshot of an Epidemic in the Republic of Panama.  

E-Print Network [OSTI]

??ABSTRACT Background: Worldwide HIV is going through a feminization and rejuvenation as more women are living with HIV/AIDS, increasing the risk of vertical transmission. Despite… (more)

Jenkins, Lorna Elizabeth

2013-01-01T23:59:59.000Z

419

Alaska APDES Enforcement Response Guide | Open Energy Information  

Open Energy Info (EERE)

search OpenEI Reference LibraryAdd to library PermittingRegulatory Guidance - GuideHandbook: Alaska APDES Enforcement Response GuidePermittingRegulatory GuidanceGuideHandbook...

420

Montana Stream Permitting Guide Webpage | Open Energy Information  

Open Energy Info (EERE)

Guide Webpage Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Montana Stream Permitting Guide Webpage Abstract Provides a guide to required stream...

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Bureau of Land Management - NEPA Web Guide | Open Energy Information  

Open Energy Info (EERE)

Guide Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Bureau of Land Management - NEPA Web Guide Abstract The NEPA Web Guide includes links to official...

422

Special Publication 800-86 Guide to Integrating Forensic  

E-Print Network [OSTI]

Special Publication 800-86 Guide to Integrating Forensic Techniques into Incident ResponseDang #12;#12;Guide to Integrating Forensic Techniques into Incident Response Recommendations A. Jeffrey, Director #12;GUIDE TO INTEGRATING FORENSIC TECHNIQUES INTO INCIDENT RESPONSE Reports

423

Complex adenovirus-vectored vaccine protects guinea pigs from three strains of Marburg virus challenges  

SciTech Connect (OSTI)

The Marburg virus (MARV), an African filovirus closely related to the Ebola virus, causes a deadly hemorrhagic fever in humans, with up to 90% mortality. Currently, treatment of disease is only supportive, and no vaccines are available to prevent spread of MARV infections. In order to address this need, we have developed and characterized a novel recombinant vaccine that utilizes a single complex adenovirus-vectored vaccine (cAdVax) to overexpress a MARV glycoprotein (GP) fusion protein derived from the Musoke and Ci67 strains of MARV. Vaccination with the cAdVaxM(fus) vaccine led to efficient production of MARV-specific antibodies in both mice and guinea pigs. Significantly, guinea pigs vaccinated with at least 5 x 10{sup 7} pfu of cAdVaxM(fus) vaccine were 100% protected against lethal challenges by the Musoke, Ci67 and Ravn strains of MARV, making it a vaccine with trivalent protective efficacy. Therefore, the cAdVaxM(fus) vaccine serves as a promising vaccine candidate to prevent and contain multi-strain infections by MARV.

Wang Danher [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Hevey, Michael [Virology Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, MD 21702-5011 (United States); Juompan, Laure Y. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Trubey, Charles M. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Raja, Nicholas U. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Deitz, Stephen B. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Woraratanadharm, Jan [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Luo Min [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Yu Hong [Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Ave., BSB 201, Charleston, SC 29403 (United States); Swain, Benjamin M. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Moore, Kevin M. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States); Dong, John Y. [Division of Bio-defense Vaccines, GenPhar Inc., 871 Lowcountry Blvd., Mount Pleasant, SC 29464 (United States) and Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Ave., BSB 201, Charleston, SC 29403 (United States)]. E-mail: dongj@genphar.com

2006-09-30T23:59:59.000Z

424

How HIV infects cells | Argonne National Laboratory  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Science Science Computing, Environment & Life Sciences Energy Engineering & Systems Analysis Photon Sciences Physical Sciences & Engineering Energy Frontier Research Centers Science Highlights Postdoctoral Researchers The brightness and energy of X-ray beams are critical properties for research. The APS Upgrade will make our X-ray beams brighter, meaning more X-rays can be focused onto a smaller, laser-like spot, allowing researchers to gather more data in greater detail in less time. How HIV infects cells October 10, 2013 Tweet EmailPrint In a long-awaited finding, an international team of scientists using high-brightness x-rays from the U.S. Department of Energy Office of Science's Advanced Photon Source at Argonne National Laboratory has determined the high-resolution atomic structure of a cell-surface receptor

425

Advanced Notification of Awards (ANA) User Guide  

Broader source: Energy.gov (indexed) [DOE]

2 2 U.S. Department of Energy Advanced Notification of Awards (ANA) User Guide A service of iManage ANA User Guide Page 2 Table of Contents Introduction ............................................................................. 3 Approval Process Overview ...................................................... 3 Role Descriptions ..................................................................... 3 Accessing the ANA system ....................................................... 5 Approving Notifications ........................................................... 8 Rejecting Notifications ........................................................... 11 Additional System Tools: Document History .......................... 15 Manual Submission: ............................................................... 16

426

Solar Photovoltaic SPECIFICATION, CHECKLIST AND GUIDE  

Broader source: Energy.gov (indexed) [DOE]

Photovoltaic Photovoltaic SPECIFICATION, CHECKLIST AND GUIDE Renewable Energy Ready Home Renewable Energy Ready Home SOLAR PHOTOVOLTAIC SPECIFICATION, CHECKLIST AND GUIDE i Table of Contents About the Renewable Energy Ready Home Specifications Assumptions of the RERH Solar Photovoltaic Specification .............................................................................. 1 Builder and Specification Limitations ............................................................................................................. 2

427

Advanced Notification of Awards (ANA) User Guide  

Broader source: Energy.gov (indexed) [DOE]

Advanced Notification of Awards Advanced Notification of Awards (ANA) User Guide A service of iManage ANA User Guide Page 2 Table of Content: Introduction........................................................................... 3 Approval Process Overview.................................................... 3 Role Descriptions................................................................... 3 Accessing the ANA system..................................................... 5 Termination Guidelines.......................................................... 9 Approving Notifications......................................................... 9 Rejecting Notifications........................................................... 13 Additional System Tools: Document History.......................... 16

428

Building Technologies Office: Advanced Energy Retrofit Guides  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Retrofit Guides Retrofit Guides Photo of the cover of the Advanced Energy Retrofit Guide for Healthcare Facilities. The Advanced Energy Retrofit Guides (AERGs) help building owners and managers as well as design and construction professionals plan, design, and implement energy efficiency upgrades in commercial buildings. The Advanced Energy Retrofit Guides (AERGs) were created to help decision makers plan, design, and implement energy improvement projects in their facilities. With energy managers in mind, they present practical guidance for kick-starting the process and maintaining momentum throughout the project life cycle. These guides are primarily reference documents, allowing energy managers to consult the particular sections that address the most pertinent topics.. Useful resources are also cited throughout the guides for further information. Each AERG is tailored specifically to the needs of a specific building type, with an emphasis on the most effective retro-commissioning and retrofit measures identified by experts familiar with those unique opportunities and challenges. The guides present a broad range of proven practices that can help energy managers take specific actions at any stage of the retrofit process, resulting in energy savings for many years to come.

429

Laser Centre Vrije Universiteit visitors guide  

E-Print Network [OSTI]

Fall 2005 Laser Centre Vrije Universiteit visitors guide #12;Laser Centre Vrije Universiteit De.de.Gijsel@few.vu.nl Website: www.nat.vu.nl/~laser Printing: Drukkerij Ponsen en Looijen, Wageningen © LCVU, Amsterdam great pleasure to present you the Visitors Guide 2005 of the Laser Centre Vrije Universiteit (LCVU

430

LORAIN COUNTY COMMUNITY COLLEGE TRANSFER GUIDE  

E-Print Network [OSTI]

LORAIN COUNTY COMMUNITY COLLEGE TRANSFER GUIDE KEY Unless stated, web-based courses 268 NURS 201 BIOG 273 BIOL 326 #12;CASE WESTERN RESERVE UNIVERSITY 2 LORAIN COUNTY COMMUNITY COLLEGE UNIVERSITY 3 LORAIN COUNTY COMMUNITY COLLEGE TRANSFER GUIDE DEPARTMENT LCCC CASE History (continued) HSTR 262

Rollins, Andrew M.

431

User Guide for San José Finance Tool  

Broader source: Energy.gov [DOE]

This user guide is intended primarily for the finance tool itself rather than an introduction to photovoltaics (PV) and PV finance. Users who do not have a basic understanding of PV systems, terminology, and financing structures are encouraged to review the documents referenced at the end of the guide...

432

Collaboration Suite Advanced Web Client User Guide  

E-Print Network [OSTI]

ZimbraTM Collaboration Suite Advanced Web Client User Guide Version 5.0 #12;Zimbra Web Client User Guide Copyright Notice Copyright © 2008 Zimbra, Inc. All rights reserved materials, onscreen publication, or Web documentation--is expressly forbidden. Zimbra and the Zimbra logo

Shepp, Larry

433

Energy from Waste: A good practice guide  

E-Print Network [OSTI]

Energy from Waste: A good practice guide #12;9 Saxon Court, St Peter's Gardens, Marefair: www.ciwm.co.uk Energy from Waste: A good practice guide ISBN: 0-902944-54-1 Published November 2003 by IWM Business Services Ltd on behalf of: Energy from Waste Working Group #12;1 Energy from Waste

Columbia University

434

An Inventor's Guide to Technology Transfer  

E-Print Network [OSTI]

An Inventor's Guide to Technology Transfer at the Massachusetts Institute of Technology on the University of Michigan's "Inventor's Guide to Technology Transfer," with adaptations for MIT and the MIT of Technology Transfer for their kind permission to use their excellent material and to the University

Reuter, Martin

435

COMM 105 Research Guide January 2014  

E-Print Network [OSTI]

://library.queensu.ca/research/guide/business The business research guide provides links to databases covering business and management, trade magazine. and includes many different subjects. I'd recommend using the business databases listed in the Business of information. Academic/scholarly reports and articles from the article databases are also required. Business

Abolmaesumi, Purang

436

Autodesk MapGuide Enterprise Implementation  

E-Print Network [OSTI]

Autodesk MapGuide® Enterprise Implementation Best Practices Arnab Ganguly, Neil Brooker ­ Autodesk GS310-3 Best practices for configuring and deploying Autodesk MapGuide Enterprise to create optimal performance for sites. About the Speakers: Arnab joined Autodesk 7 years ago as an applications engineer

Ahmad, Sajjad

437

Clean Cities 2011 Vehicle Buyer's Guide  

SciTech Connect (OSTI)

The 2011 Clean Cities Light-Duty Vehicle Buyer's Guide is a consumer publication that provides a comprehensive list of commercially available alternative fuel and advanced vehicles in model year 2011. The guide allows for side-by-side comparisons of fuel economy, price, emissions, and vehicle specifications.

Not Available

2011-01-01T23:59:59.000Z

438

marchand@cui.unige.ch Collection Guiding  

E-Print Network [OSTI]

marchand@cui.unige.ch Collection Guiding: Multimedia Collection Browsing and Visualization Stéphane Marchand-Maillet Viper ­ CVML ­ University of Geneva marchand@cui.unige.ch http://viper.unige.ch marchand Perspectives marchand@cui.unige.ch © http://viper.unige.ch ­ December 2004 3 Collection Guiding: Browsing

Genève, Université de

439

Guide to VA Mental Health Services  

E-Print Network [OSTI]

Guide to VA Mental Health Services for Veterans and Families Keitha R Beamer, MSN: PMHCNS, BC; CARN-AP #12;The most complex and dangerous conflicts, the most harrowing operations, and the most deadly wars.va.gov/vetdata/index.asp #12;Guiding Principals · Focus on Recovery · Coordinated Care for the Whole Person · Mental Health

Hardy, Christopher R.

440

Purchasing Card (PCard) Program and User Guide  

E-Print Network [OSTI]

Purchasing Card (PCard) Program and User Guide Updated November 25, 2013 St. Francis Xavier University Visa® Purchasing Card #12;Purchasing Card (PCard) Program Guide November 25, 2013 Page 1 of 18.................................................................................................................................................2 Financial Services ­ Business Office ­ PCard Administrators

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

EERE Program Management Guide - About the Program Management Guide  

Broader source: Energy.gov (indexed) [DOE]

Program Managers and their teams need to know what to do, how to do it, and why it needs to be done. User instructions help make EERE's program management processes and tools easier. The DOE and EERE Strategic Management System (SMS) provides a needed standard approach. Need for a Program Management "Operator's Guide" Program management is complex and difficult. It requires knowledge and discipline as well as a broad range of concepts, processes, and tools to be carried out effectively and efficiently. In the Office of Energy Efficiency and Renewable Energy (EERE) environment, many Program Managers and their teams bring to the job educational backgrounds and work experiences that are focused on science and technology. To complement that background they

442

Test Acquisition Guide | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Test Acquisition Guide Test Acquisition Guide Test Acquisition Guide Regulatory requirements for the acquisition process are set forth in the Federal Acquisition Regulation (FAR) and are supplemented in the Department of Energy Acquisition Regulation (DEAR). FAR 1.301 provides for the issuance of additional internal agency guidance, including designations and delegations of authority, assignments of responsibilities, work-flow procedures, and internal reporting requirements. The DOE Acquisition Guide serves this purpose by identifying relevant internal standard operating procedures to be followed by both procurement and program personnel who are involved in various aspects of the acquisition process. The Guide also is intended to be a repository of best practices found throughout the agency

443

Study Guides and Activities | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Education » Study Guides and Activities Education » Study Guides and Activities Study Guides and Activities A Toolkit for Teachers and Parents Thank you for considering fossil energy education in your classroom curriculum. The U.S. Department of Energy's Office of Fossil Energy is excited to present printable study guides and activities emphasizing the importance of coal, natural gas, and petroleum to our everyday lives. More importantly, we hope to familiarize students with the science and technologies that make using fossil fuels cleaner. We hope you find our information useful. If you have any comments or suggestions regarding our educational materials, please contact us. Elementary School Coal Study Guide: Focuses on the basics of coal, history of coal use, conversion of coal into electricity, and climate change concerns.

444

Department of Energy Personal Property Management Guide  

Office of Legacy Management (LM)

http://www.directives.doe.gov Office of Management http://www.directives.doe.gov Office of Management DOE G 580.1-1 NOT MEASUREMENT SENSITIVE 12-7-05 DEPARTMENT OF ENERGY PERSONAL PROPERTY MANAGEMENT GUIDE An Implementation Guide for the DOE Personal Property Management Program [This Guide describes suggested nonmandatory approaches for meeting requirements. Guides are not requirements documents and are not construed as requirements in any audit or appraisal for compliance with the parent Policy, Order, Notice, or Manual.] U.S. Department of Energy Washington, D.C. 20585 DOE G 580.1-1 i 12-7-05 FOREWORD This Personal Property Management Guide is the second Department of Energy (DOE) directive developed to replace most parts of the DOE Property Management Regulations

445

Department of Energy Personal Property Management Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

http://www.directives.doe.gov Office of Management http://www.directives.doe.gov Office of Management DOE G 580.1-1 NOT MEASUREMENT SENSITIVE 12-7-05 DEPARTMENT OF ENERGY PERSONAL PROPERTY MANAGEMENT GUIDE An Implementation Guide for the DOE Personal Property Management Program [This Guide describes suggested nonmandatory approaches for meeting requirements. Guides are not requirements documents and are not construed as requirements in any audit or appraisal for compliance with the parent Policy, Order, Notice, or Manual.] U.S. Department of Energy Washington, D.C. 20585 DOE G 580.1-1 i 12-7-05 FOREWORD This Personal Property Management Guide is the second Department of Energy (DOE) directive developed to replace most parts of the DOE Property Management Regulations

446

Resource Guides | Building Energy Codes Program  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Resource Guides Resource Guides Download a Guide Air Leakage Architects Beyond Code Code Officials Residential section only Commercial section only HVAC Controls Lighting Guide Policy Makers Energy code compliance often requires more than a list of basic requirements. In many cases, additional information is needed to better understand the intent of and need for energy code provisions. This critical need for information can help clarify the code intent, empowering those who effectively design and construct buildings to meet code, as well as those who conduct plan reviews and inspections to verify compliance. This helps to assure the intent behind the energy code is implemented in practice. To address these needs, the U.S. Department of Energy Building Energy Codes Program has developed a number of guides available to support the model

447

Guide to Financial Assistance | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Guide to Financial Assistance Guide to Financial Assistance Guide to Financial Assistance Guide to Financial Assistance The Guide to Financial Assistance is a reference document that provides a compilation of non-regulatory information and guidance related to the implementation of existing statutory and regulatory requirements. Regulatory requirements are contained in the DOE Financial Assistance Rules, 10 CFR Part 600 and applicable program rules. Each year DOE obligates nearly $2 billion on financial assistance actions in the form of grants and cooperative agreements to states, local and tribal governments, universities, non-profit organizations, for-profit organizations, and individuals. This guidance is intended to help DOE staff carry out its financial assistance activities. Information contained herein is intended to be

448

Guide to Financial Assistance | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Guide to Financial Assistance Guide to Financial Assistance Guide to Financial Assistance Guide to Financial Assistance The Guide to Financial Assistance is a reference document that provides a compilation of non-regulatory information and guidance related to the implementation of existing statutory and regulatory requirements. Regulatory requirements are contained in the DOE Financial Assistance Rules, 10 CFR Part 600 and applicable program rules. Each year DOE obligates nearly $2 billion on financial assistance actions in the form of grants and cooperative agreements to states, local and tribal governments, universities, non-profit organizations, for-profit organizations, and individuals. This guidance is intended to help DOE staff carry out its financial assistance activities. Information contained herein is intended to be

449

Canada's Fuel Consumption Guide | Open Energy Information  

Open Energy Info (EERE)

Canada's Fuel Consumption Guide Canada's Fuel Consumption Guide Jump to: navigation, search Tool Summary Name: Canada's Fuel Consumption Guide Agency/Company /Organization: Natural Resources Canada Focus Area: Fuels & Efficiency Topics: Analysis Tools Website: oee.nrcan.gc.ca/transportation/tools/fuel-consumption-guide/fuel-consu Natural Resources Canada has compiled fuel consumption ratings for passenger cars and light-duty pickup trucks, vans, and special purpose vehicles sold in Canada. The website links to the Fuel Consumption Guide and allows users to search for vehicles from current and past model years. It also provides information about vehicle maintenance and other practices to reduce fuel consumption. How to Use This Tool This tool is most helpful when using these strategies:

450

Ultrasonic guided waves in eccentric annular pipes  

SciTech Connect (OSTI)

This paper studies the feasibility of using ultrasonic guided waves to rapidly inspect tubes and pipes for possible eccentricity. While guided waves are well established in the long range inspection of structures such as pipes and plates, studies for more complex cross sections are limited and analytical solutions are often difficult to obtain. Recent developments have made the Semi Analytical Finite Element (SAFE) method widely accessible for researchers to study guided wave properties in complex structures. Here the SAFE method is used to study the effect of eccentricity on the modal structures and velocities of lower order guided wave modes in thin pipes of diameters typically of interest to the industry. Results are validated using experiments. The paper demonstrates that even a small eccentricity in the pipe can strongly affect guided wave mode structures and velocities and hence shows potential for pipe eccentricity inspection.

Pattanayak, Roson Kumar; Balasubramaniam, Krishnan; Rajagopal, Prabhu [Centre for NDE, Indian Institute of Technology - Madras Chennai 600036, T. N. (India)

2014-02-18T23:59:59.000Z

451

DOE Guide to Working with Tribal Nations  

Broader source: Energy.gov (indexed) [DOE]

for DOE Employees for DOE Employees WORKING WITH INDIAN TRIBAL NATIONS December 2000 ACKNOWLEDGMENTS The guide was developed for the U.S. Department of Energy by Creighton & Creighton, Inc., under contract to the Office of Intergovernmental and Public Accountability (EM-11). The guide was reviewed by representatives of several tribes and DOE staff who work regularly with tribal nations. However, Creighton & Creighton, Inc., remains responsible for the editorial content of this guide. This guide includes materials taken from guides prepared by the U.S. Environmental Protection Agency, the U.S. Forest Service, and the National Congress of American Indians and used without attribution. Creighton & Creighton, Inc., and the Department of Energy wish to thank these organizations for permission to use these

452

CEQ NEPA & EMS Guide Overview  

Broader source: Energy.gov (indexed) [DOE]

CEQ Publishes NEPA-EMS Guide CEQ Publishes NEPA-EMS Guide "The Council on Environmental Quality (CEQ) has published Aligning NEPA Processes with Environmental Management Systems - A Guide for NEPA and EMS Practitioner. This guide provides practitioners with a tool to improve NEPA implementation and achieve the environmental sustainability goals laid out in NEPA and Executive Order 13423: 'to create and maintain conditions, under which humans and nature can exist in productive harmony, that permit fulfilling the social, economic, and other requirements of present and future generations of Americans.'" James L. Connaughton Chairman, CEQ * CEQ's goal is to continue developing tools to improve and modernize NEPA. This Guide was developed help practitioners make NEPA implementation more effective and

453

Federal Energy Management Program: Guide to Integrating Renewable Energy in  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Federal Energy Management Program: Guide to Federal Energy Management Program: Guide to Integrating Renewable Energy in Federal Construction to someone by E-mail Share Federal Energy Management Program: Guide to Integrating Renewable Energy in Federal Construction on Facebook Tweet about Federal Energy Management Program: Guide to Integrating Renewable Energy in Federal Construction on Twitter Bookmark Federal Energy Management Program: Guide to Integrating Renewable Energy in Federal Construction on Google Bookmark Federal Energy Management Program: Guide to Integrating Renewable Energy in Federal Construction on Delicious Rank Federal Energy Management Program: Guide to Integrating Renewable Energy in Federal Construction on Digg Find More places to share Federal Energy Management Program: Guide

454

GAO Cost Estimating and Assessment Guide | Department of Energy  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Cost Estimating and Assessment Guide GAO Cost Estimating and Assessment Guide GAO 12-Step Estimating Process.pdf More Documents & Publications EIR SOP Septmebr 2010 Microsoft Word...

455

Cost Estimating Guide - DOE Directives, Delegations, and Requirements  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

G 413.3-21, Cost Estimating Guide by Ruben Sanchez Functional areas: Budget and Financial Management, Financial Management This Guide provides uniform guidance and best practices...

456

Former Tribal Energy Program Intern Guides Tribes Toward a More...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Former Tribal Energy Program Intern Guides Tribes Toward a More Sustainable Path Former Tribal Energy Program Intern Guides Tribes Toward a More Sustainable Path January 30, 2015 -...

457

Guide to Government Witnessing and Review of Measurement and...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Guide to Government Witnessing and Review of Measurement and Verification Activities Guide to Government Witnessing and Review of Measurement and Verification Activities Document...

458

CHP Education and Outreach Guide to State and Federal Government...  

Broader source: Energy.gov (indexed) [DOE]

CHP Education and Outreach Guide to State and Federal Government, Updated October 2005 CHP Education and Outreach Guide to State and Federal Government, Updated October 2005 This...

459

Solar Powering Your Community: A Guide for Local Governments...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Solar Powering Your Community: A Guide for Local Governments (Book), Energy Efficiency & Renewable Energy (EERE) Solar Powering Your Community: A Guide for Local Governments...

460

EERE Program Management Guide - Appendix Q | Department of Energy  

Energy Savers [EERE]

Appendix Q EERE Program Management Guide - Appendix Q Appendix Q provides a comprehensive glossary of terms used throughout the rest of the PMI guide. pmguideappendixq.pdf More...

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Montana Environmental Policy Act Guide | Open Energy Information  

Open Energy Info (EERE)

Policy Act Guide Jump to: navigation, search OpenEI Reference LibraryAdd to library PermittingRegulatory Guidance - GuideHandbook: Montana Environmental Policy Act...

462

Procuring Fuel Cells for Stationary Power: A Guide for Federal...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

1 Procuring Fuel Cells for Stationary Power: A Guide for Federal Facility Decision Makers Federal Facilities Guide to Fuel Cells May 8, 2012 - Outline * Distributed Generation and...

463

National Energy Policy Act Guide for State Energy Program and...  

Broader source: Energy.gov (indexed) [DOE]

National Energy Policy Act Guide for State Energy Program and Energy Efficiency and Conservation Block Grant Projects National Energy Policy Act Guide for State Energy Program and...

464

Microsoft Word - AcqGuide34pt1.doc  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

2005) 2 * DOE Acquisition Guide, Chapter 70.8, Appendix B, "DOE Performance-Based Contracting Guide" * Office of Engineering and Construction Management Information Center...

465

Combined Heat and Power (CHP) Resource Guide for Hospital Applications...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Combined Heat and Power (CHP) Resource Guide for Hospital Applications, 2007 Combined Heat and Power (CHP) Resource Guide for Hospital Applications, 2007 The objective of this 2007...

466

Guide to Using Combined Heat and Power for Enhancing Reliability...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Guide to Using Combined Heat and Power for Enhancing Reliability and Resiliency in Buildings Guide to Using Combined Heat and Power for Enhancing Reliability and Resiliency in...

467

Limited-Notice Performance Test Inspectors Guide | Department...  

Office of Environmental Management (EM)

Limited-Notice Performance Test Inspectors Guide Limited-Notice Performance Test Inspectors Guide October 2014 This document describes the Limited-Notice Performance Testing...

468

Primary Science of Energy Student Guide (42 Activities) | Department...  

Energy Savers [EERE]

Primary Science of Energy Student Guide (42 Activities) Primary Science of Energy Student Guide (42 Activities) Information about Primary Science of Energy, 42 student activities...

469

EERE Program Management Guide - About the Program Management...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

The Introduction describes the need for an Operator's Guide, provides information on content and the relationship between the guide and the EERE Program Management Initiative,...

470

Thermodynamics Student Guide (6 Activities) | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Student Guide (6 Activities) Thermodynamics Student Guide (6 Activities) Information about Thermodynamics, six student activities on energy basics for grades 5-8 and 9-12....

471

Guide to Permitting Electric Transmission Lines in Wyoming |...  

Open Energy Info (EERE)

Permitting Electric Transmission Lines in Wyoming Jump to: navigation, search OpenEI Reference LibraryAdd to library PermittingRegulatory Guidance - GuideHandbook: Guide to...

472

Procuring Fuel Cells for Stationary Power: A Guide for Federal...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Procuring Fuel Cells for Stationary Power: A Guide for Federal Facility Decision Makers Procuring Fuel Cells for Stationary Power: A Guide for Federal Facility Decision Makers This...

473

Procuring Fuel Cells for Stationary Power: A Guide for Federal...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Procuring Fuel Cells for Stationary Power: A Guide for Federal Decision Makers Procuring Fuel Cells for Stationary Power: A Guide for Federal Decision Makers Download presentation...

474

Solid-State NMR Studies of HIV-1 Capsid Protein Assemblies. ...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of HIV-1 Capsid Protein Assemblies. Abstract: In mature HIV-1 virions, the 26.6 kDa CA protein is assembled into a characteristic cone-shaped core (capsid) that encloses the...

475

Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens  

DOE Patents [OSTI]

The present invention relates to mosaic clade M HIV-1 Env polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Korber, Bette T. (Los Alamos, NM); Fischer, William (Los Alamos, NM); Liao, Hua-Xin (Durham, NC); Haynes, Barton F. (Durham, NC); Letvin, Norman (Boston, MA); Hahn; Beatrice H. (Birmingham, AL)

2011-05-31T23:59:59.000Z

476

Special Article: Significant Risk Versus Acceptable Risk in Dental Treatment of HIV-Infected Individuals  

Science Journals Connector (OSTI)

Dentists are obligated to treat HIV-infected individuals by legal and professional code regardless of personal bias, level of training, or area of specialty. Refusal to treat HIV-infected individuals irrespect...

Albert W. Whitehead; John Hlaudy

2002-06-01T23:59:59.000Z

477

HIV-1 Tat trans-activates in the Absence of its Target  

Science Journals Connector (OSTI)

The human immunodeficiency virus type 1 (HIV-1) is the etiologic agent of the ... immunodeficiency disease syndrome (AIDS). Transcription of HIV-1 is regulated by the virally encoded trans-activator, Tat (Varmus,...

Mark J. Selby; B. Matija Peterlin

1991-01-01T23:59:59.000Z

478

E-Print Network 3.0 - anti-dendritic cell hiv Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

COS cells, pgTAT(HIV-1) induces the efficient synthesis... cells (16). The genomic HIV-2 tat ... Source: Le, Shu-Yun - Center for Cancer Research Nanobiology Progam,...

479

E-Print Network 3.0 - acyclovir delays hiv-1 Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HIV-1genes... .06.006 Stochastic Gene Expression in a Lentiviral Positive-Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic... that the phage's lysislysogeny life-cycle...

480

Bcl-2 upregulation by HIV-1 tat during infection of primary human macrophages in culture  

Science Journals Connector (OSTI)

The ability of cells of the human monocyte/macrophage lineage to host HIV-1 replication while resisting cell death is ... susceptible to apoptosis. Here we report that HIV-1BAL...infection of primary human monocy...

Mingjie Zhang; Xingxiang Li; Xiaowu Pang; Linna Ding…

Note: This page contains sample records for the topic "guide hiv vaccine" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Analysis of HIV-1 Tat effects inXenopus laevis embryos  

Science Journals Connector (OSTI)

Tat is one of the regulatory proteins of the HIV-1 virus. To date, besides the ... activity, a myriad of effects exerted by HIV-1 Tat on cellular and viral genes have been ... present study investigated the in vi...

Dr. Serenella Venanzi; Olivier H. J. Destrée…

482

N-Terminal HIV-1 Tat Nonapeptides as Inhibitors of Dipeptidyl Peptidase IV. Conformational Characterization  

Science Journals Connector (OSTI)

Compared to the N-terminal nonapeptide of the HIV-1 Tat protein as inhibitor of activity of DP ... is supposed to mediate the immunosuppressive effects of HIV-1 Tat, the Ile5 and Leu6 analogues showed strongly re...

Carmen Mrestani-Klaus; Annett Fengler…

2002-01-01T23:59:59.000Z

483

E-Print Network 3.0 - anti-hiv drug combinations Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

of four individual anti-HIV shRNAs might already suffice... to express a single anti-HIV tat shRNA in cultured lymphoma cells and found it ... Source: Kay, Mark A. -...

484

HIV-1 Tat protein and endothelium: From protein/cell interaction to AIDS-associated pathologies  

Science Journals Connector (OSTI)

Tat protein, the transactivating factor of the human immunodeficiency virus type 1 (HIV-1), is a small cationic polypeptide that can be released from HIV-1 infected cells. Extracellular Tat elicits different biol...

Marco Rusnati; Marco Presta

2002-01-01T23:59:59.000Z

485

Extracellular HIV Tat and Tat cysteine rich peptide increase CCR5 expression in monocytes  

Science Journals Connector (OSTI)

In our previous work we reported that HIV Tat and 6 cysteine rich peptides of Tat induce tumor necrosis factor-related apoptosis-induced...et al...., 2003). Here our results showed that HIV Tat and Tat cysteine r...

Zheng Lin; Yang Yi-da; Lu Guo-cai…

2005-07-01T23:59:59.000Z

486

Antibody to HIV-1 Tat protein inhibits the replication of virus in culture  

Science Journals Connector (OSTI)

The HIV-1 transactivator protein Tat is essential for viral replication. Tat is released from infected cells and can be taken up and transactivate HIV-LTR in LTR-CAT transfected cell lines. ... shows that the add...

L. Steinaa; A. M. Sørensen; J. O. Nielsen; J. E. S. Hansen

1994-01-01T23:59:59.000Z

487

Regulation of HIV-1 Gene Expression by the Transactivator Protein Tat  

Science Journals Connector (OSTI)

The regulation of HIV-1 gene expression is an area of intense investigation. Like all retroviruses, HIV-1 integrates into cellular DNA, and its gene expression is dependent on host cell transcription factors a...

R. B. Gaynor

1995-01-01T23:59:59.000Z

488

Evaluation of HIV-1 Tat induced neurotoxicity in rat cortical cell culture  

Science Journals Connector (OSTI)

In a substantial number of cases, Human Immunodeficiency Virus type 1 (HIV-1) infection causes neuronal cell loss and ... loss. Here we studied the effect of HIV-1 Tat in primary rat neuronal cells as a ... cell ...

Aleida Pérez; Albert W. Probert; Kevin K. W. Wang…

2001-01-01T23:59:59.000Z

489

Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein. Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide...

490

E-Print Network 3.0 - access hiv services Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

HIV Summary: on the prevention of HIV and STIs to women who do not frequently access health care services. Although prenatal care... fees. Mother-infant pairs had access to...

491

E-Print Network 3.0 - africa estimating hiv Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

hiv Search Powered by Explorit Topic List Advanced Search Sample search results for: africa estimating hiv Page: << < 1 2 3 4 5 > >> 1 November 30, 2006, 12:00 AM Three Things...

492

Surveillance Guides - Work Control Process  

Broader source: Energy.gov (indexed) [DOE]

Work Control Process Work Control Process 1.0 Objective The objective of this surveillance guide is to provide lines of inquiry for evaluating the effectiveness of the contractor's work control process. Users should be cognizant that the lines of inquiry need to be further tailored to fit specific facilities or activities in accordance with contractual mechanisms such as Maintenance Implementation Plans, Conduct of Operations Implementation Plans, and the Integrated Safety Management System Description. 2.0 References 2.1 DOE 4330.4B Maintenance Management Program 2.2 48 CFR 1970.5204-2 Department of Energy Acquisition Regulations 2.3 DOE O 5480.19, Conduct of Operations 2.4 10 CFR 830.120, Quality Assurance 3.0 Requirements Implemented This surveillance is conducted to verify implementation of Core

493

Surveillance Guides - Identification of Hazards  

Broader source: Energy.gov (indexed) [DOE]

Identification of Hazards Identification of Hazards 1.0 Objective The objective of this surveillance is to evaluate the effectiveness of the contractor's hazards identification programs. Surveillance activities encompass maintenance and implementation of safety basis documentation (SARs, ISBs, BIOs, JCOs, HASPs etc) as well as activity level hazards identification via JHAs, AJHAs, JSAs etc.) 2.0 References 2.1 DOE 4330.4B Maintenance Management Program 2.2 48 CFR 1970 Department of Energy Acquisition Regulations 2.3 DOE O 5480.21, Unreviewed Safety Questions 2.4 DOE O 5480.23, Nuclear Safety Analysis Reports 3.0 Requirements Implemented This surveillance verifies implementation of guiding principle #5 and core value #2 as specified in 48 CFR 1970.5204-2 (b) (5) and (c) (2) respectively. Additionally, it verifies implementation of

494

Licensing Guide and Sample License  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

TEI:HNOL06Y TRANSFER WORKIN6 6ROUP TEI:HNOL06Y TRANSFER WORKIN6 6ROUP Lic:en!iing Guide and Sample Lic:en!ie ·~ ICan.u City Plan I OFermilab ~OAK ~RIDGE Nuioul~.

495

Residential Retrofit Program Design Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Technical Assistance Program Technical Assistance Program Residential Retrofit Program Design Guide May 2011 This work has been performed by the Vermont Energy Investment Corporation (VEIC) and Energy Futures Group (EFG), under the Contract No. 4200000341 with Oak Ridge National Laboratory which is managed by UT-Battelle, LLC under Contract with the US Department of Energy No. DE-AC05-00OR22725. This document was prepared in collaboration with a partnership of companies under this contract. The partnership is led by the Vermont Energy Investment Corporation (VEIC), and includes the following companies: American Council for an Energy Efficient Economy (ACEEE), Energy Futures Group (EFG), Midwest Energy Efficiency Alliance (MEEA), Northwest Energy Efficiency Alliance (NEEA), Northeast Energy Efficiency Partnership (NEEP), Natural

496

Wet Corn Milling Energy Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

307 307 ERNEST ORLANDO LAWRENCE BERKELEY NATIONAL LABORATORY Energy Efficiency Improvement and Cost Saving Opportunities for the Corn Wet Milling Industry An ENERGY STAR Guide for Energy and Plant Managers Christina Galitsky, Ernst Worrell and Michael Ruth Environmental Energy Technologies Division Sponsored by the U.S. Environmental Protection Agency July 2003 Disclaimer This document was prepared as an account of work sponsored by the United States Government. While this document is believed to contain correct information, neither the United States Government nor any agency thereof, nor The Regents of the University of California, nor any of their employees, makes any warranty, express or implied, or assumes any legal responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product,

497

ENERGY STAR Student Activity Guide  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

program helping program helping businesses and individuals fight global warming through superior energy efficiency. 1 STUDENT ACTIVITY GUIDE Introduction Colleges and Universities-Energy Use and Its Environmental Impact How does the energy use of your college or university impact the environment? Most of the energy generated by power plants in the United States comes from burning fossil fuels. Greenhouse gases, which contribute to climate change, are released into the atmosphere as these fossil fuels are burned. When we use less energy at school, at work, and at home, fewer fossil fuels are consumed, which means less pollution and a way to help mitigate global warming. Did you know that: ƒ Commercial buildings and industrial facilities, including college and university buildings, generate about 50 percent

498

An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and Toxin B Receptor Binding Domains of Clostridium difficile Induces Protective Antibody Responses In Vivo  

Science Journals Connector (OSTI)

...Immunity and Vaccines An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and...these advantages make newer, synthetic DNA-based immunizations a desirable...our work demonstrates that a synthetic DNA vaccine encoding the toxin RBDs...

Scott M. Baliban; Amanda Michael; Berje Shammassian; Shikata Mudakha; Amir S. Khan; Simon Cocklin; Isaac Zentner; Brian P. Latimer; Laurent Bouillaut; Meredith Hunter; Preston Marx; Niranjan Y. Sardesai; Seth L. Welles; Jeffrey M. Jacobson; David B. Weiner; Michele A. Kutzler

2014-07-14T23:59:59.000Z

499

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines  

Science Journals Connector (OSTI)

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines ... Here we report the design and synthesis of a 1,669-nucleotide, single-stranded DNA mol. ... These DL-DNAs induced greater amts. of tumor necrosis factor-? and interleukin-6 from RAW264.7 macrophage-like cells than did a mixt. of Y-DNA with the same sequences as the corresponding DL-DNA. ...

Xiaowei Liu; Yang Xu; Tao Yu; Craig Clifford; Yan Liu; Hao Yan; Yung Chang

2012-07-03T23:59:59.000Z

500

HIV-1 Fusion Peptide Decreases Bending Energy and Promotes Curved Fusion Intermediates  

E-Print Network [OSTI]

HIV-1 Fusion Peptide Decreases Bending Energy and Promotes Curved Fusion Intermediates Stephanie in human immunodeficiency virus (HIV) infection is fusion between the viral envelope and the T x-ray scattering is that the bending modulus KC is greatly reduced upon addition of the HIV fusion

Nagle, John F.