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Sample records for gdp interest rates

  1. Energy Efficiency Interest Rate Reduction Program

    Broader source: Energy.gov [DOE]

    For new and existing home purchases that are rated 6 Star or 5 Star Plus, applicants are eligible for an interest rate reduction for the first $200,000 of the loan amount, with a blended interest...

  2. Credit-Based Interest Rate Spread for Title XVII

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Credit-Based Interest Rate Spread for Title XVII The Loan Programs Office (LPO) is announcing that a credit-based interest rate spread will be added to certain loans that are issued by the Federal Financing Bank (FFB) and backed by a 100 percent loan guarantee issued by the Department of Energy. Loans issued by the FFB will carry an interest rate calculated by the following formula: Interest Rate = Applicable U.S. Treasury Rate for the tenor of the loan + 37.5 basis points (bps) FFB liquidity

  3. Prediction of interest rate using CKLS model with stochastic parameters

    SciTech Connect (OSTI)

    Ying, Khor Chia; Hin, Pooi Ah

    2014-06-19

    The Chan, Karolyi, Longstaff and Sanders (CKLS) model is a popular one-factor model for describing the spot interest rates. In this paper, the four parameters in the CKLS model are regarded as stochastic. The parameter vector φ{sup (j)} of four parameters at the (J+n)-th time point is estimated by the j-th window which is defined as the set consisting of the observed interest rates at the j′-th time point where j≤j′≤j+n. To model the variation of φ{sup (j)}, we assume that φ{sup (j)} depends on φ{sup (j−m)}, φ{sup (j−m+1)},…, φ{sup (j−1)} and the interest rate r{sub j+n} at the (j+n)-th time point via a four-dimensional conditional distribution which is derived from a [4(m+1)+1]-dimensional power-normal distribution. Treating the (j+n)-th time point as the present time point, we find a prediction interval for the future value r{sub j+n+1} of the interest rate at the next time point when the value r{sub j+n} of the interest rate is given. From the above four-dimensional conditional distribution, we also find a prediction interval for the future interest rate r{sub j+n+d} at the next d-th (d≥2) time point. The prediction intervals based on the CKLS model with stochastic parameters are found to have better ability of covering the observed future interest rates when compared with those based on the model with fixed parameters.

  4. Applicable Interest Rates for Slice Product (contracts/slice...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    is the Prime Rate for Large Banks (the base rate on corporate loans posted by at least 75% of the nation's 30 largest Banks) as reported in the Wall Street Journal on the first...

  5. Low-Interest Rates Entice Philadelphians to Reach for the Stars |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Low-Interest Rates Entice Philadelphians to Reach for the Stars Low-Interest Rates Entice Philadelphians to Reach for the Stars For many Philadelphia area residents, getting a loan for home energy efficiency improvements is a no brainer when it's offered at a 0.99% fixed interest rate. EnergyWorks in Philadelphia is using low-interest loan rates to incentivize homeowners by tying the interest rate to the number of energy efficiency measures incorporated into the home,

  6. Quantitative law describing market dynamics before and after interest-rate change

    SciTech Connect (OSTI)

    Petersen, Alexander M.; Wang Fengzhong; Stanley, H. Eugene; Havlin, Shlomo

    2010-06-15

    We study the behavior of U.S. markets both before and after U.S. Federal Open Market Commission meetings and show that the announcement of a U.S. Federal Reserve rate change causes a financial shock, where the dynamics after the announcement is described by an analog of the Omori earthquake law. We quantify the rate n(t) of aftershocks following an interest-rate change at time T and find power-law decay which scales as n(t-T)approx(t-T){sup -O}MEGA, with OMEGA positive. Surprisingly, we find that the same law describes the rate n{sup '}(|t-T|) of 'preshocks' before the interest-rate change at time T. This study quantitatively relates the size of the market response to the news which caused the shock and uncovers the presence of quantifiable preshocks. We demonstrate that the news associated with interest-rate change is responsible for causing both the anticipation before the announcement and the surprise after the announcement. We estimate the magnitude of financial news using the relative difference between the U.S. Treasury Bill and the Federal Funds effective rate. Our results are consistent with the 'sign effect', in which 'bad news' has a larger impact than 'good news'. Furthermore, we observe significant volatility aftershocks, confirming a 'market under-reaction' that lasts at least one trading day.

  7. New Contract Helps Portsmouth GDP Cleanup

    Broader source: Energy.gov [DOE]

    To accelerate the Portsmouth GDP cleanup efforts left over from the Cold War, the Department of Energy made a huge step forward in our nuclear environmental cleanup efforts.

  8. Accommodation of GDP-Linked Sugars in the Active Site of GDP-Perosamine Synthase

    SciTech Connect (OSTI)

    Cook, Paul D.; Carney, Amanda E.; Holden, Hazel M.

    2009-01-12

    Perosamine (4-amino-4,6-dideoxy-d-mannose), or its N-acetylated form, is one of several dideoxy sugars found in the O-antigens of such infamous Gram-negative bacteria as Vibrio cholerae O1 and Escherichia coli O157:H7. It is added to the bacterial O-antigen via a nucleotide-linked version, namely GDP-perosamine. Three enzymes are required for the biosynthesis of GDP-perosamine starting from mannose 1-phosphate. The focus of this investigation is GDP-perosamine synthase from Caulobacter crescentus, which catalyzes the final step in GDP-perosamine synthesis, the conversion of GDP-4-keto-6-deoxymannose to GDP-perosamine. The enzyme is PLP-dependent and belongs to the aspartate aminotransferase superfamily. It contains the typically conserved active site lysine residue, which forms a Schiff base with the PLP cofactor. Two crystal structures were determined for this investigation: a site-directed mutant protein (K186A) complexed with GDP-perosamine and the wild-type enzyme complexed with an unnatural ligand, GDP-3-deoxyperosamine. These structures, determined to 1.6 and 1.7 {angstrom} resolution, respectively, revealed the manner in which products, and presumably substrates, are accommodated within the active site pocket of GDP-perosamine synthase. Additional kinetic analyses using both the natural and unnatural substrates revealed that the K{sub m} for the unnatural substrate was unperturbed relative to that of the natural substrate, but the k{sub cat} was lowered by a factor of approximately 200. Taken together, these studies shed light on why GDP-perosamine synthase functions as an aminotransferase whereas another very similar PLP-dependent enzyme, GDP-4-keto-6-deoxy-d-mannose 3-dehydratase or ColD, catalyzes a dehydration reaction using the same substrate.

  9. Characterization of a Ras Mutant with Identical GDP- and GTP-Bound Structures

    SciTech Connect (OSTI)

    Ford, B.; Boykevisch, S; Zhao, C; Kunzelmann, S; Bar-Sagi, D; Herrmann, C; Nassar, N

    2009-01-01

    We previously characterized the G60A mutant of Ras and showed that the switch regions of the GTP-bound but not the GDP-bound form of this mutant adopt an 'open conformation' similar to that seen in nucleotide-free Ras. Here, we mutate Lys147 of the conserved {sup 145}SAK{sup 147} motif in the G60A background and characterize the resulting double mutant (DM). We show that RasDM is the first structure of a Ras protein with identical GDP- and GTP-bound structures. Both structures adopt the open conformation of the active form of RasG60A. The increase in the accessible surface area of the nucleotide is consistent with a 4-fold increase in its dissociation rate. Stopped-flow experiments show no major difference in the two-step kinetics of association of GDP or GTP with the wild type, G60A, or RasDM. Addition of Sos fails to accelerate nucleotide exchange. Overexpression of the G60A or double mutant of Ras in COS-1 cells fails to activate Erk and shows a strong dominant negative effect. Our data suggest that flexibility at position 60 is required for proper Sos-catalyzed nucleotide exchange and that structural information is somehow shared among the switch regions and the different nucleotide binding motifs.

  10. Structures of NodZ ?1,6-fucosyltransferase in complex with GDP and GDP-fucose

    SciTech Connect (OSTI)

    Brzezinski, Krzysztof; Dauter, Zbigniew; Jaskolski, Mariusz

    2012-02-01

    Crystal structures of the bacterial ?1,6-fucosyltransferase NodZ in complex with GDP and GDP-fucose are presented. Rhizobial NodZ ?1,6-fucosyltransferase (?1,6-FucT) catalyzes the transfer of the fucose (Fuc) moiety from guanosine 5?-diphosphate-?-l-fucose to the reducing end of the chitin oligosaccharide core during Nod-factor (NF) biosynthesis. NF is a key signalling molecule required for successful symbiosis with a legume host for atmospheric nitrogen fixation. To date, only two ?1,6-FucT structures have been determined, both without any donor or acceptor molecule that could highlight the structural background of the catalytic mechanism. Here, the first crystal structures of ?1,6-FucT in complex with its substrate GDP-Fuc and with GDP, which is a byproduct of the enzymatic reaction, are presented. The crystal of the complex with GDP-Fuc was obtained through soaking of native NodZ crystals with the ligand and its structure has been determined at 2.35 resolution. The fucose residue is exposed to solvent and is disordered. The enzymeproduct complex crystal was obtained by cocrystallization with GDP and an acceptor molecule, penta-N-acetyl-l-glucosamine (penta-NAG). The structure has been determined at 1.98 resolution, showing that only the GDP molecule is present in the complex. In both structures the ligands are located in a cleft formed between the two domains of NodZ and extend towards the C-terminal domain, but their conformations differ significantly. The structures revealed that residues in three regions of the C-terminal domain, which are conserved among ?1,2-, ?1,6- and protein O-fucosyltransferases, are involved in interactions with the sugar-donor molecule. There is also an interaction with the side chain of Tyr45 in the N-terminal domain, which is very unusual for a GT-B-type glycosyltransferase. Only minor conformational changes of the protein backbone are observed upon ligand binding. The only exception is a movement of the loop located between

  11. Oil-Consumption-Weighted GDP: Description, Calculation, and Comparison

    U.S. Energy Information Administration (EIA) Indexed Site

    Oil-Consumption-Weighted GDP: Description, Calculation, and Comparison Vipin Arora, Tyler Hodge, and Tancred Lidderdale May 2016 Independent Statistics & Analysis www.eia.gov U.S. Energy Information Administration Washington, DC 20585 This paper is released to encourage discussion and critical comment. The analysis and conclusions expressed here are those of the authors and not necessarily those of the U.S. Energy Information Administration. Our thanks to Vinay Tripathi, summer intern from

  12. Structures of NodZ [alpha]1,6-fucosyltransferase in complex with GDP and GDP-fucose

    SciTech Connect (OSTI)

    Brzezinski, Krzysztof; Dauter, Zbigniew; Jaskolski, Mariusz

    2012-03-26

    Rhizobial NodZ {alpha}1,6-fucosyltransferase ({alpha}1,6-FucT) catalyzes the transfer of the fucose (Fuc) moiety from guanosine 5'-diphosphate-{beta}-L-fucose to the reducing end of the chitin oligosaccharide core during Nod-factor (NF) biosynthesis. NF is a key signaling molecule required for successful symbiosis with a legume host for atmospheric nitrogen fixation. To date, only two {alpha}1,6-FucT structures have been determined, both without any donor or acceptor molecule that could highlight the structural background of the catalytic mechanism. Here, the first crystal structures of {alpha}1,6-FucT in complex with its substrate GDP-Fuc and with GDP, which is a byproduct of the enzymatic reaction, are presented. The crystal of the complex with GDP-Fuc was obtained through soaking of native NodZ crystals with the ligand and its structure has been determined at 2.35 {angstrom} resolution. The fucose residue is exposed to solvent and is disordered. The enzyme-product complex crystal was obtained by cocrystallization with GDP and an acceptor molecule, penta-N-acetyl-L-glucosamine (penta-NAG). The structure has been determined at 1.98 {angstrom} resolution, showing that only the GDP molecule is present in the complex. In both structures the ligands are located in a cleft formed between the two domains of NodZ and extend towards the C-terminal domain, but their conformations differ significantly. The structures revealed that residues in three regions of the C-terminal domain, which are conserved among {alpha}1,2-, {alpha}1,6- and protein O-fucosyltransferases, are involved in interactions with the sugar-donor molecule. There is also an interaction with the side chain of Tyr45 in the N-terminal domain, which is very unusual for a GT-B-type glycosyltransferase. Only minor conformational changes of the protein backbone are observed upon ligand binding. The only exception is a movement of the loop located between strand {beta}C2 and helix {alpha}C3. In addition, there is

  13. Roughness Optimization at High Modes for GDP CHx Microshells

    SciTech Connect (OSTI)

    Theobald, M.; Dumay, B.; Chicanne, C.; Barnouin, J.; Legaie, O.; Baclet, P.

    2004-03-15

    For the ''Megajoule'' Laser (LMJ) facility of the CEA, amorphous hydrogenated carbon (a-C:H) is the nominal ablator to be used for inertial confinement fusion (ICF) experiments. These capsules contain the fusible deuterium-tritium mixture to achieve ignition. Coatings are prepared by glow discharge polymerization (GDP) with trans-2-butene and hydrogen. The films properties have been investigated. Laser fusion targets must have optimized characteristics: a diameter of about 2.4 mm for LMJ targets, a thickness up to 175 {mu}m, a sphericity and a thickness concentricity better than 99% and an outer and an inner roughness lower than 20 nm at high modes. The surface finish of these laser fusion targets must be extremely smooth to minimize hydrodynamic instabilities.Movchan and Demchishin, and later Thornton introduced a structure zone model (SZM) based on both evaporated and sputtered metals. They investigated the influence of base temperature and the sputtering gas pressure on structure and properties of thick polycrystalline coatings of nickel, titanium, tungsten, aluminum oxide. An original cross-sectional analysis by atomic force microscopy (AFM) allows amorphous materials characterization and permits to make an analogy between the amorphous GDP material and the existing model (SZM). The purpose of this work is to understand the relationship between the deposition parameters, the growing structures and the surface roughness.The coating structure as a function of deposition parameters was first studied on plane silicon substrates and then optimized on PAMS shells. By adjusting the coating parameters, the structures are modified, and in some case, the high modes roughness decreases dramatically.

  14. Cloning and characterization of GDP-perosamine synthetase (Per) from Escherichia coli O157:H7 and synthesis of GDP-perosamine in vitro

    SciTech Connect (OSTI)

    Zhao Guohui; Liu Jun; Liu Xiang; Chen Min; Zhang Houcheng Wang, Peng George

    2007-11-23

    GDP-perosamine synthetase (Per, E.C. not yet classified) is important to the synthesis of Escherichia coli O157:H7 O-antigen. The mutant in per gene can disrupt the synthesis of O157 O-antigen. In this study, GDP-perosamine synthetase was cloned from E. coli O157:H7 and over-expressed in E. coli BL21 (DE3). The recombinant His-tagged Per fusion protein was a decamer with molecular weight of 431 kDa. The optimal pH value of this recombinant protein was 7.5. The divalent ions had no significant effect on Per-catalyzed reaction. The K{sub m} and K{sub cat}/K{sub m} for GDP-4-keto-6-deoxy-D-mannose were 0.09 mM and 2.1 x 10{sup 5} M{sup -1} S{sup -1}, and those for L-glutamate were 2 mM and 0.52 x 10{sup 5} M{sup -1}S{sup -1}, respectively. Per was used to synthesize GDP-perosamine from GDP-mannose together with recombinant GDP-mannose dehydratase (GMD, E.C. 4.2.1.47). The purified GDP-perosamine was identified by MS and NMR. In summary, this work provided a feasible approach for the synthesis of GDP-perosamine which can lead to the study of LPS biosynthesis of pathogenic E. coli O157:H7.

  15. Mechanical Properties of Thin GDP Shells Used as Cryogenic Direct Drive Targets at OMEGA

    SciTech Connect (OSTI)

    Nikroo, A.; Czechowicz, D.G.; Chen, K.C.; Dicken, M.; Morris, C.; Andrews, R.; Greenwood, A.; Castillo, E.

    2004-03-15

    Thin glow discharge polymer (GDP) shells are currently used as the targets for cryogenic direct drive laser fusion experiments. These shells need to be filled with nearly 1000 atm of D{sub 2} and cooled to cryogenic temperatures without failing due to buckling and bursting pressures they experience in this process. Therefore, the mechanical and permeation properties of these shells are of utmost importance in successful and rapid filling with D{sub 2}. In this paper, we present an overview of buckle and burst pressures of several different types of GDP shells. These include those made using traditional GDP deposition parameters ('standard GDP') using a high deposition pressure and using modified parameters ('strong GDP') of low deposition pressure that leads to more robust shells.

  16. MECHANICAL PROPERTIES OF THIN GDP SHELLS USED AS CRYOGENIC DIRECT DRIVE TARGETS AT OMEGA

    SciTech Connect (OSTI)

    NIKROO,A; CZECHOWICZ,D; CHEN,K.C; DICKEN,M; MORRIS,C; ANDREWS,R; GREENWOOD,A.L; CASTILLO,E

    2003-06-01

    OAK-B135 Thin glow discharge polymer (GDP) shells are currently used as the targets for cryogenic direct drive laser fusion experiments. These shells need to be filled with nearly 1000 atm of D{sub 2} and cooled to cryogenic temperatures without failing due to buckling and bursting pressures they experience in this process. Therefore, the mechanical and permeation properties of these shells are of utmost importance in successful and rapid filling with D{sub 2}. In this paper, they present an overview of buckle and burst pressures of several different types of GDP shells. These include those made using traditional GDP deposition parameters (standard GDP) using a high deposition pressure and using modified parameters (strong GDP) of low deposition pressure that leads to more robust shells.

  17. Biochemical characterization of GDP-L-fucose de novo synthesis pathway in fungus Mortierella alpina

    SciTech Connect (OSTI)

    Ren, Yan; Perepelov, Andrei V.; Wang, Haiyan; Zhang, Hao; Knirel, Yuriy A.; Wang, Lei; Chen, Wei

    2010-01-22

    Mortierella alpina is a filamentous fungus commonly found in soil, which is able to produce large amount of polyunsaturated fatty acids. L-Fucose is an important sugar found in a diverse range of organisms, playing a variety of biological roles. In this study, we characterized the de novo biosynthetic pathway of GDP-L-fucose (the nucleotide-activated form of L-fucose) in M. alpina. Genes encoding GDP-D-mannose 4,6-dehydratase (GMD) and GDP-keto-6-deoxymannose 3,5-epimerase/4-reductase (GMER) were expressed heterologously in Escherichia coli. The recombinant enzymes were produced as His-tagged fusion proteins. Conversion of GDP-mannose to GDP-4-keto-6-deoxy mannose by GMD and GDP-4-keto-6-deoxy mannose to GDP-L-fucose by GMER were analyzed by capillary electrophoresis, electro-spray ionization-mass spectrometry, and nuclear magnetic resonance spectroscopy. The k{sub m} values of GMD for GDP-mannose and GMER for GDP-4-keto-6-deoxy mannose were determined to be 0.77 mM and 1.047 mM, respectively. Both NADH and NADPH may be used by GMER as the coenzyme. The optimum temperature and pH were determined to be 37 {sup o}C and pH 9.0 (GMD) or pH 7.0 (GMER). Divalent cations are not required for GMD and GMER activity, and the activities of both enzymes may be enhanced by DTT. To our knowledge this is the first report on the characterization of GDP-L-fucose biosynthetic pathway in fungi.

  18. X-ray, NMR, and Mutational Studies of the Catalytic Cycle of the GDP-Mannose Mannosyl Hydrolase Reaction

    SciTech Connect (OSTI)

    Gabelli,S.; Azurmendi, H.; Bianchet, M.; Amzel, L.; Mildva, A.

    2006-01-01

    GDP-mannose hydrolase catalyzes the hydrolysis with inversion of GDP-{alpha}-D-hexose to GDP and {beta}-D-hexose by nucleophilic substitution by water at C1 of the sugar. Two new crystal structures (free enzyme and enzyme-substrate complex), NMR, and site-directed mutagenesis data, combined with the structure of the enzyme-product complex reported earlier, suggest a four-stage catalytic cycle. An important loop (L6, residues 119-125) contains a ligand to the essential Mg{sup 2+} (Gln-123), the catalytic base (His-124), and three anionic residues. This loop is not ordered in the X-ray structure of the free enzyme due to dynamic disorder, as indicated by the two-dimensional 1H-15N HMQC spectrum, which shows selective exchange broadening of the imidazole nitrogen resonances of His-124 (k{sub ex} = 6.6 x 10{sup 4} s{sup -1}). The structure of the enzyme-Mg{sup 2+}-GDP-mannose substrate complex of the less active Y103F mutant shows loop L6 in an open conformation, while the structure of the enzyme-Mg{sup 2+}-GDP product complex showed loop L6 in a closed, 'active' conformation. 1H-15N HMQC spectra show the imidazole N of His-124 to be unprotonated, appropriate for general base catalysis. Substituting Mg{sup 2+} with the more electrophilic metal ions Mn{sup 2+} or Co{sup 2+} decreases the pK{sub a} in the pH versus k{sub cat} rate profiles, showing that deprotonation of a metal-bound water is partially rate-limiting. The H124Q mutation, which decreases k{sub cat} 103.4-fold and largely abolishes its pH dependence, is rescued by the Y103F mutation, which increases k{sub cat} 23-fold and restores its pH dependence. The structural basis of the rescue is the fact that the Y103F mutation shifts the conformational equilibrium to the open form moving loop L6 out of the active site, thus permitting direct access of the specific base hydroxide from the solvent. In the proposed dissociative transition state, which occurs in the closed, active conformation of the enzyme, the

  19. Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway

    SciTech Connect (OSTI)

    Webb, N.A.; Mulichak, A.M.; Lam, J.S.; Rocchetta, H.L.; Garavito, R.M.

    2010-03-08

    D-Rhamnose is a rare 6-deoxy monosaccharide primarily found in the lipopolysaccharide of pathogenic bacteria, where it is involved in host-bacterium interactions and the establishment of infection. The biosynthesis of D-rhamnose proceeds through the conversion of GDP-D-mannose by GDP-D-mannose 4,6-dehydratase (GMD) to GDP-4-keto-6-deoxymannose, which is subsequently reduced to GDP-D-rhamnose by a reductase. We have determined the crystal structure of GMD from Pseudomonas aeruginosa in complex with NADPH and GDP. GMD belongs to the NDP-sugar modifying subfamily of the short-chain dehydrogenase/reductase (SDR) enzymes, all of which exhibit bidomain structures and a conserved catalytic triad (Tyr-XXX-Lys and Ser/Thr). Although most members of this enzyme subfamily display homodimeric structures, this bacterial GMD forms a tetramer in the same fashion as the plant MUR1 from Arabidopsis thaliana. The cofactor binding sites are adjoined across the tetramer interface, which brings the adenosyl phosphate moieties of the adjacent NADPH molecules to within 7 {angstrom} of each other. A short peptide segment (Arg35-Arg43) stretches into the neighboring monomer, making not only protein-protein interactions but also hydrogen bonding interactions with the neighboring cofactor. The interface hydrogen bonds made by the Arg35-Arg43 segment are generally conserved in GMD and MUR1, and the interacting residues are highly conserved among the sequences of bacterial and eukaryotic GMDs. Outside of the Arg35-Arg43 segment, residues involved in tetrameric contacts are also quite conserved across different species. These observations suggest that a tetramer is the preferred, and perhaps functionally relevant, oligomeric state for most bacterial and eukaryotic GMDs.

  20. Rate Of Oxidation Of Plasma Polymer (GDP or CH) (Technical Report...

    Office of Scientific and Technical Information (OSTI)

    Subject: 36 MATERIALS SCIENCE; 42 ENGINEERING; ATOMS; COATINGS; DESIGN; OXIDATION; PLASMA; PLASTICS; POLYMERS; REMOVAL; SPECIFICATIONS Word Cloud More Like This Full Text preview ...

  1. Rate Of Oxidation Of Plasma Polymer (GDP or CH) (Technical Report...

    Office of Scientific and Technical Information (OSTI)

    Based on this result we believe the NIF capsule specification for O can safely be lowered to 0.2 atom %, and this level should be used in future design calculations. Authors: Cook, ...

  2. A Rac1--GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium

    SciTech Connect (OSTI)

    Prehna, G.; Stebbins, C

    2007-01-01

    The Rho family of small GTPases represent well characterized signaling molecules that regulate many cellular functions such as actin cytoskeletal arrangement and the cell cycle by acting as molecular switches. A Rac1-GDP-Zn complex has been crystallized in space group P3221 and its crystal structure has been solved at 1.9 {angstrom} resolution. These trigonal crystals reveal the unexpected ability of Rac1 to coordinate Zn atoms in a tetrahedral fashion by use of its biologically relevant switch I and switch II regions. Upon coordination of zinc, the switch I region is stabilized in the GDP-bound conformation and contributes to a Rac1 trimer in the asymmetric unit. Zinc coordination causes switch II to adopt a novel conformation with a symmetry-related molecule. Additionally, zinc was found to displace magnesium from its octahedral coordination at switch I, although GDP binding remained stable. This structure represents the first reported Rac1-GDP-Zn complex, which further underscores the conformational flexibility and versatility of the small GTPase switch regions.

  3. A Rac1-GDP Trimer Complex Binds Zinc with Tetrahedral and Octahedral Coordination, Displacing Magnesium

    SciTech Connect (OSTI)

    Prehna,G.; Stebbins, E.

    2007-01-01

    The Rho family of small GTPases represent well characterized signaling molecules that regulate many cellular functions such as actin cytoskeletal arrangement and the cell cycle by acting as molecular switches. A Rac1-GDP-Zn complex has been crystallized in space group P3{sub 2}21 and its crystal structure has been solved at 1.9 {angstrom} resolution. These trigonal crystals reveal the unexpected ability of Rac1 to coordinate Zn atoms in a tetrahedral fashion by use of its biologically relevant switch I and switch II regions. Upon coordination of zinc, the switch I region is stabilized in the GDP-bound conformation and contributes to a Rac1 trimer in the asymmetric unit. Zinc coordination causes switch II to adopt a novel conformation with a symmetry-related molecule. Additionally, zinc was found to displace magnesium from its octahedral coordination at switch I, although GDP binding remained stable. This structure represents the first reported Rac1-GDP-Zn complex, which further underscores the conformational flexibility and versatility of the small GTPase switch regions.

  4. Heterocyclic anions of astrobiological interest

    SciTech Connect (OSTI)

    Cole, Callie A.; Demarais, Nicholas J.; Bierbaum, Veronica M. [Department of Chemistry and Biochemistry, 215 UCB, University of Colorado, Boulder, CO 80309 (United States); Yang, Zhibo [Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019 (United States); Snow, Theodore P., E-mail: Callie.Cole@colorado.edu, E-mail: Nicholas.Demarais@colorado.edu, E-mail: Veronica.Bierbaum@colorado.edu, E-mail: Zhibo.Yang@ou.edu, E-mail: Theodore.Snow@colorado.edu [Department of Astrophysical and Planetary Sciences, 391 UCB, University of Colorado, Boulder, CO 80309 (United States)

    2013-12-20

    As more complex organic molecules are detected in the interstellar medium, the importance of heterocyclic molecules to astrobiology and the origin of life has become evident. 2-Aminothiazole and 2-aminooxazole have recently been suggested as important nucleotide precursors, highlighting azoles as potential prebiotic molecules. This study explores the gas-phase chemistry of three deprotonated azoles: oxazole, thiazole, and isothiazole. For the first time, their gas-phase acidities are experimentally determined with bracketing and H/D exchange techniques, and their reactivity is characterized with several detected interstellar neutral molecules (N{sub 2}O, O{sub 2}, CO, OCS, CO{sub 2}, and SO{sub 2}) and other reactive species (CS{sub 2}, CH{sub 3}Cl, (CH{sub 3}){sub 3}CCl, and (CH{sub 3}){sub 3}CBr). Rate constants and branching fractions for these reactions are experimentally measured using a modified commercial ion trap mass spectrometer whose kinetic data are in good accord with those of a flowing afterglow apparatus reported here. Last, we have examined the fragmentation patterns of these deprotonated azoles to elucidate their destruction mechanisms in high-energy environments. All experimental data are supported and complemented by electronic structure calculations at the B3LYP/6-311++G(d,p) and MP2(full)/aug-cc-pVDZ levels of theory.

  5. Cloning, purification and preliminary crystallographic analysis of the Bacillus subtilis GTPase YphCGDP complex

    SciTech Connect (OSTI)

    Xu, Ling; Muench, Stephen P.; Roujeinikova, Anna; Sedelnikova, Svetlana E.; Rice, David W.

    2006-05-01

    Crystals of a selenomethionine-incorporated YphCGDP complex have been grown using the hanging-drop vapour-diffusion method and polyethylene glycol as a precipitating agent. The Bacillus subtilis YphC gene encodes an essential GTPase thought to be involved in ribosome binding and whose protein product may represent a target for the development of a novel antibacterial agent. Sequence analysis reveals that YphC belongs to the EngA family of GTPases, which uniquely contain two adjacent GTP-binding domains. Crystals of a selenomethionine-incorporated YphCGDP complex have been grown using the hanging-drop vapour-diffusion method and polyethylene glycol as a precipitating agent. The crystals belong to space group P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 62.71, b = 65.05, c = 110.61 , and have one molecule in the asymmetric unit. Data sets at three different wavelengths were collected on a single crystal to 2.5 resolution at the Daresbury SRS in order to solve the structure by MAD. Ultimately, analysis of YphC in complex with GDP may allow a greater understanding of the EngA family of essential GTPases.

  6. Letter of Interest Example

    Broader source: Energy.gov [DOE]

    Sample letter of interest describes the FEMP Call for Technical Services for American Recovery and Reinvestment Act funds.

  7. Conflict of Interest Policy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    conflict of interest Conflict of Interest Policy Conflict of Interest between the NIF Technical Review Committee Member and review of proposal All Conflicts of Interest between a reviewer and the proposals being reviewed should be reported to the Committee Chair and the NIF User Office Director prior to accepting lead reviewer assignments. Conflicts include being formally listed on the proposal, having supervision responsibility for the PI, or in any way receiving significant benefit from the

  8. Structural basis of GDP release and gating in G protein coupled Fe[superscript 2+] transport

    SciTech Connect (OSTI)

    Guilfoyle, Amy; Maher, Megan J.; Rapp, Mikaela; Clarke, Ronald; Harrop, Stephen; Jormakka, Mika

    2009-09-29

    G proteins are key molecular switches in the regulation of membrane protein function and signal transduction. The prokaryotic membrane protein FeoB is involved in G protein coupled Fe{sup 2+} transport, and is unique in that the G protein is directly tethered to the membrane domain. Here, we report the structure of the soluble domain of FeoB, including the G protein domain, and its assembly into an unexpected trimer. Comparisons between nucleotide free and liganded structures reveal the closed and open state of a central cytoplasmic pore, respectively. In addition, these data provide the first observation of a conformational switch in the nucleotide-binding G5 motif, defining the structural basis for GDP release. From these results, structural parallels are drawn to eukaryotic G protein coupled membrane processes.

  9. Interest & Training Announcements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Interest-Training-Announcements Sign In About | Careers | Contact | Investors | bpa.gov Search News & Us Expand News & Us Projects & Initiatives Expand Projects &...

  10. Mutational, Structural, and Kinetic Evidence for a Dissociative Mechanism in the GDP-mannose Mannosyl Hydrolase Reaction

    SciTech Connect (OSTI)

    Xia,Z.; Azurmendi, H.; lairson, L.; Withers, S.; Gabelli, S.; Bianchet, M.; Amzel, L.; Mildvan, A.

    2005-01-01

    GDP-mannose hydrolase (GDPMH) catalyzes the hydrolysis of GDP-{alpha}-D-sugars by nucleophilic substitution with inversion at the anomeric C1 atom of the sugar, with general base catalysis by H124. Three lines of evidence indicate a mechanism with dissociative character. First, in the 1.3 Angstrom X-ray structure of the GDPMH-Mg{sup 2+}-GDP{center_dot}Tris{sup +} complex, the GDP leaving group interacts with five catalytic components: R37, Y103, R52, R65, and the essential Mg{sup 2+}. As determined by the effects of site-specific mutants on k{sub cat}, these components contribute factors of 24-, 100-, 309-, 24-, and {ge}10{sup 5}-fold, respectively, to catalysis. Both R37 and Y103 bind the {beta}-phosphate of GDP and are only 5.0 Angstroms apart. Accordingly, the R37Q/Y103F double mutant exhibits partially additive effects of the two single mutants on k{sub cat}, indicating cooperativity of R37 and Y103 in promoting catalysis, and antagonistic effects on K{sub m}. Second, the conserved residue, D22, is positioned to accept a hydrogen bond from the C2-OH group of the sugar undergoing substitution at C1, as was shown by modeling an {alpha}-D-mannosyl group into the sugar binding site. The D22A and D22N mutations decreased k{sub cat} by factors of 10{sup 2.1} and 10{sup 2.6}, respectively, for the hydrolysis of GDP-{alpha}-D-mannose, and showed smaller effects on K{sub m}, suggesting that the D22 anion stabilizes a cationic oxocarbenium transition state. Third, the fluorinated substrate, GDP-2F-{alpha}-D-mannose, for which a cationic oxocarbenium transition state would be destabilized by electron withdrawal, exhibited a 16-fold decrease in k{sub cat} and a smaller, 2.5-fold increase in K{sub m}. The D22A and D22N mutations further decreased the k{sub cat} with GDP-2F-{alpha}-D-mannose to values similar to those found with GDP-{alpha}-D-mannose, and decreased the K{sub m} of the fluorinated substrate. The choice of histidine as the general base over glutamate, the

  11. Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in G[alpha] Subunits

    SciTech Connect (OSTI)

    Preininger, Anita M.; Funk, Michael A.; Oldham, William M.; Meier, Scott M.; Johnston, Christopher A.; Adhikary, Suraj; Kimple, Adam J.; Siderovski, David P.; Hamm, Heidi E.; Iverson, Tina M.

    2009-06-01

    Heterotrimeric G proteins (Galphabetagamma) transmit signals from activated G protein-coupled receptors (GPCRs) to downstream effectors through a guanine nucleotide signaling cycle. Numerous studies indicate that the carboxy-terminal alpha5 helix of Galpha subunits participates in Galpha-receptor binding, and previous EPR studies suggest this receptor-mediated interaction induces a rotation and translation of the alpha5 helix of the Galpha subunit [Oldham, W. M., et al. (2006) Nat. Struct. Mol. Biol. 13, 772-777]. On the basis of this result, an engineered disulfide bond was designed to constrain the alpha5 helix of Galpha(i1) into its EPR-measured receptor-associated conformation through the introduction of cysteines at position 56 in the alpha1 helix and position 333 in the alpha5 helix (I56C/Q333C Galpha(i1)). A functional mimetic of the EPR-measured alpha5 helix dipole movement upon receptor association was additionally created by introduction of a positive charge at the amino terminus of this helix, D328R Galpha(i1). Both proteins exhibit a dramatically elevated level of basal nucleotide exchange. The 2.9 A resolution crystal structure of I56C/Q333C Galpha(i1) in complex with GDP-AlF(4)(-) reveals the shift of the alpha5 helix toward the guanine nucleotide binding site that is anticipated by EPR measurements. The structure of the I56C/Q333C Galpha(i1) subunit further revealed altered positions for the switch regions and throughout the Galpha(i1) subunit, accompanied by significantly elevated crystallographic temperature factors. Combined with previous evidence in the literature, the structural analysis supports the critical role of electrostatics of the alpha5 helix dipole and overall conformational variability during nucleotide release.

  12. Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms

    SciTech Connect (OSTI)

    Simonetti, Angelita; Fabbretti, Attilio; Hazemann, Isabelle; Jenner, Lasse; Gualerzi, Claudio O.; Klaholz, Bruno P.

    2013-06-01

    The crystal structures of the eubacterial translation initiation factor 2 in apo form and with bound GDP and GTP reveal conformational changes upon nucleotide binding and hydrolysis, notably of the catalytically important histidine in the switch II region. Translation initiation factor 2 (IF2) is involved in the early steps of bacterial protein synthesis. It promotes the stabilization of the initiator tRNA on the 30S initiation complex (IC) and triggers GTP hydrolysis upon ribosomal subunit joining. While the structure of an archaeal homologue (a/eIF5B) is known, there are significant sequence and functional differences in eubacterial IF2, while the trimeric eukaryotic IF2 is completely unrelated. Here, the crystal structure of the apo IF2 protein core from Thermus thermophilus has been determined by MAD phasing and the structures of GTP and GDP complexes were also obtained. The IF2GTP complex was trapped by soaking with GTP in the cryoprotectant. The structures revealed conformational changes of the protein upon nucleotide binding, in particular in the P-loop region, which extend to the functionally relevant switch II region. The latter carries a catalytically important and conserved histidine residue which is observed in different conformations in the GTP and GDP complexes. Overall, this work provides the first crystal structure of a eubacterial IF2 and suggests that activation of GTP hydrolysis may occur by a conformational repositioning of the histidine residue.

  13. Environmental/Interest Groups

    Office of Legacy Management (LM)

    Environmental/Interest Groups Miamisburg Mound Community Improvement Corporation (MMCIC) Mike J. Grauwelman President P.O. Box 232 Miamisburg, OH 45343-0232 (937) 865-4462 Email: mikeg@mound.com Mound Reuse Committee See MMCIC Mound Environmental Safety and Health Sharon Cowdrey President 5491 Weidner Road Springboro, OH 45066 (937) 748-4757 No email address available Mound Museum Association Dr. Don Sullenger President Mound Advanced Technology Center 720 Mound Road Miamisburg, OH 45342-6714

  14. Upgraded Coal Interest Group

    SciTech Connect (OSTI)

    Evan Hughes

    2009-01-08

    The Upgraded Coal Interest Group (UCIG) is an EPRI 'users group' that focuses on clean, low-cost options for coal-based power generation. The UCIG covers topics that involve (1) pre-combustion processes, (2) co-firing systems and fuels, and (3) reburn using coal-derived or biomass-derived fuels. The UCIG mission is to preserve and expand the economic use of coal for energy. By reducing the fuel costs and environmental impacts of coal-fired power generation, existing units become more cost effective and thus new units utilizing advanced combustion technologies are more likely to be coal-fired.

  15. Decreasing Interest Paid in Federal Utility Energy Service Contracts...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    interest rate, interest payments over the payment period are less than monthly payments. ... In some cases, finance companies prefer that the annual payment be made on December 1 so ...

  16. The Structure of the MUR1 GDP-mannose 4,67-deydratase from A. thaliana: Implications for Ligand Binding Specificity

    SciTech Connect (OSTI)

    Mulichak, A.M.; Bonin, C.P.; Reiter, W.-D.; Garavito, R.M.

    2010-03-08

    GDP-D-mannose 4,6-dehydratase catalyzes the first step in the de novo synthesis of GDP-L-fucose, the activated form of L-fucose, which is a component of glycoconjugates in plants known to be important to the development and strength of stem tissues. We have determined the three-dimensional structure of the MUR1 dehydratase isoform from Arabidopsis thaliana complexed with its NADPH cofactor as well as with the ligands GDP and GDP-D-rhamnose. MUR1 is a member of the nucleoside-diphosphosugar modifying subclass of the short-chain dehydrogenase/reductase enzyme family, having homologous structures and a conserved catalytic triad of Lys, Tyr, and Ser/Thr residues. MUR1 is the first member of this subfamily to be observed as a tetramer, the interface of which reveals a close and intimate overlap of neighboring NADP{sup +}-binding sites. The GDP moiety of the substrate also binds in an unusual syn conformation. The protein-ligand interactions around the hexose moiety of the substrate support the importance of the conserved triad residues and an additional Glu side chain serving as a general base for catalysis. Phe and Arg side chains close to the hexose ring may serve to confer substrate specificity at the O2 position. In the MUR1/GDP-D-rhamnose complex, a single unique monomer within the protein tetramer that has an unoccupied substrate site highlights the conformational changes that accompany substrate binding and may suggest the existence of negative cooperativity in MUR1 function.

  17. ARM - Arctic Meetings of Interest

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Related Information Collaborations Meetings of Interest Data Sources ARM Data Discovery Browser NSA Data Past ARM NSA campaigns NCARUCAR National Oceanic and Atmospheric ...

  18. Novel protein and Mg[superscript 2+] configurations in the Mg[superscript 2+] GDP Complex of the SRP GTPase ffh

    SciTech Connect (OSTI)

    Focia, Pamela J.; Alam, Hena; Lu, Thanh; Ramirez, Ursula D.; Freymann, Douglas M.

    2010-03-05

    Ffh is the signal sequence recognition and targeting subunit of the prokaryotic signal recognition particle (SRP). Previous structural studies of the NG GTPase domain of Ffh demonstrated magnesium-dependent and magnesium-independent binding conformations for GDP and GMPPNP that are believed to reflect novel mechanisms for exchange and activation in this member of the GTPase superfamily. The current study of the NG GTPase bound to Mg{sup 2+} GDP reveals two new binding conformations - in the first the magnesium interactions are similar to those seen previously, however, the protein undergoes a conformational change that brings a conserved aspartate into its second coordination sphere. In the second, the protein conformation is similar to that seen previously, but the magnesium coordination sphere is disrupted so that only five oxygen ligands are present. The loss of the coordinating water molecule, at the position that would be occupied by the oxygen of the {gamma}-phosphate of GTP, is consistent with that position being privileged for exchange during phosphate release. The available structures of the GDP-bound protein provide a series of structural snapshots that illuminate steps along the pathway of GDP release following GTP hydrolysis.

  19. Interested Parties - MIT | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    56.49 KB) More Documents & Publications Interested Parties - Morgan Wright Interested Parties - Patrick Murphy Interested Parties - Nextfuels

  20. Interested Parties - Myriant | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    (48.48 KB) More Documents & Publications Interested Parties - Myriant Interested Parties - NRG Energy Interested Parties - 1603 Program Discussion

  1. Interested Parties - NRG Energy | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    (50.11 KB) More Documents & Publications Interested Parties - Energy Solutions Interested Parties - Myriant Interested Parties - 1603 Program Discussion

  2. Interested Parties - Morgan Wright | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Morgan Wright Interested Parties - Morgan Wright Lobbyist_Disclosure.pdf (24.65 KB) More Documents & Publications Interested Parties - MIT Interested Parties - Patrick Murphy Interested Parties - Nextfuels

  3. Interested Parties - Xtreme Power | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Xtreme Power Interested Parties - Xtreme Power (50.34 KB) More Documents & Publications Interested Parties - XtremePower Interested Parties - Myriant Interested Parties - NRG Energy

  4. Interested Parties - MEMA | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Interested Parties - MEMA 08-14-10MEMA.pdf (21.72 KB) More Documents & Publications Interested Parties - Chrystler Interested Parties - Smith Dawson & Andrews Interested Parties - ...

  5. Structural Studies of the Nudix GDP-mannose Hydrolase from E. coli Reveals a New Motif for Mannose Recognition

    SciTech Connect (OSTI)

    A Boto; W Xu; J Jakoncic; A Pannuri; T Romeo; M Bessman; S Gabelli; L Amzel

    2011-12-31

    The Nudix hydrolase superfamily, characterized by the presence of the signature sequence GX5EX7REUXEEXGU (where U is I, L, or V), is a well-studied family in which relations have been established between primary sequence and substrate specificity for many members. For example, enzymes that hydrolyze the diphosphate linkage of ADP-ribose are characterized by having a proline 15 amino acids C-terminal of the Nudix signature sequence. GDPMK is a Nudix enzyme that conserves this characteristic proline but uses GDP-mannose as the preferred substrate. By investigating the structure of the GDPMK alone, bound to magnesium, and bound to substrate, the structural basis for this divergent substrate specificity and a new rule was identified by which ADP-ribose pyrophosphatases can be distinguished from purine-DP-mannose pyrophosphatases from primary sequence alone. Kinetic and mutagenesis studies showed that GDPMK hydrolysis does not rely on a single glutamate as the catalytic base. Instead, catalysis is dependent on residues that coordinate the magnesium ions and residues that position the substrate properly for catalysis. GDPMK was thought to play a role in biofilm formation because of its upregulation in response to RcsC signaling; however, GDPMK knockout strains show no defect in their capacity of forming biofilms.

  6. Interested Parties - NYU | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    3-30-2010NYU.pdf More Documents & Publications Interested Parties - ARPA-E National Association of Manufacturers Interested Parties - Myriant Interested Parties - Dow Chemical

  7. Interested Parties - Myriant | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    06-09-10Myriant.pdf More Documents & Publications Interested Parties - Dow Chemical Interested Parties - XtremePower Interested Parties - ARPA-E National Association of ...

  8. Communications from Interested Parties | Department of Energy

    Office of Environmental Management (EM)

    September 14, 2010 Interested Parties - Xtreme Power September 3, 2010 Interested Parties - Smith Dawson & Andrews August 10, 2010 Interested Parties - MEMA previous 1 2 3 4 5 next

  9. Low-Interest Loans for Customer-Side Distributed Resources

    Broader source: Energy.gov [DOE]

    The maximum total amount of financing for projects under this program is $150 million. Capital costs and project-development costs are eligible. Interest rates are fixed and will be determined at...

  10. BooNE: Interesting Facts

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Interesting Facts About the BooNE experiment: BooNE is the only experiment to search the entire range covered by the LSND oscillation signal. First proposed in 1997, BooNE will be ready to collect data in summer, 2002. The BooNE collaboration is small by high energy physics standards, having 65 physicists from 13 instiutions. If BooNE detects a supernova, it will send an automatic signal to telescopes around the world describing its position. BooNE collaboration - click to enlarge About the

  11. GDP-L-fucose: {beta}-D-galactoside 2-{alpha}-Lfucosyltransferases, DNA sequences encoding the same, method for producing the same and a method of genotyping a person

    DOE Patents [OSTI]

    Lowe, J.B.; Lennon, G.; Rouquier, S.; Giorgi, D.; Kelly, R.J.

    1998-09-15

    The gene encoding GDP-L-fucose: {beta}-D-Galactoside 2-{alpha}-Lfucosyltransferase has been cloned, and a mutation in this gene has been found to be responsible for an individual being a non-secretor. 30 figs.

  12. GDP-L-fucose: .beta.-D-galactoside 2-.alpha.-L-fucosyltransferases, DNA sequences encoding the same, method for producing the same and a method of genotyping a person

    DOE Patents [OSTI]

    Lowe, John B.; Lennon, Gregory; Rouquier, Sylvie; Giorgi, Dominique; Kelly, Robert J.

    1998-01-01

    The gene encoding GDP-L-fucose: .beta.-D-Galactoside 2-.alpha.-L-fucosyltransferase has been cloned, and a mutation in this gene has been found to be responsible for an individual being a non-secretor.

  13. Rate Information

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases Rate Information Current Power Rates Current Transmission Rates...

  14. Interested Parties - Shipp | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    4-5-2010_Shipp.pdf (13.47 KB) More Documents & Publications Interested Parties - SEIA Interested Parties - NYU Lobbyist Disclosure Form - AltEn

  15. The R6A-1 peptide binds to switch II of G{alpha}{sub i1} but is not a GDP-dissociation inhibitor

    SciTech Connect (OSTI)

    Willard, Francis S. . E-mail: fwillard@med.unc.edu; Siderovski, David P.

    2006-01-27

    Heterotrimeric G-proteins are molecular switches that convert signals from membrane receptors into changes in intracellular physiology. Recently, several peptides that bind heterotrimeric G-protein {alpha} subunits have been isolated including the novel G{alpha}{sub i1} . GDP binding peptides R6A and KB-752. The R6A peptide and its minimized derivative R6A-1 interact with G{alpha}{sub i1} . GDP. Based on spectroscopic analysis of BODIPYFL-GTP{gamma}S binding to G{alpha}{sub i1}, it has been reported that R6A-1 has guanine nucleotide dissociation inhibitor (GDI) activity against G{alpha}{sub i1} [W.W. Ja, R.W. Roberts, Biochemistry 43 (28) (2004) 9265-9275]. Using radioligand binding, we show that R6A-1 is not a GDI for G{alpha}{sub i1} subunits. Furthermore, we demonstrate that R6A-1 reduces the fluorescence quantum yield of the G{alpha}{sub i1}-BODIPYFL-GTP{gamma}S complex, thus explaining the previously reported GDI activity as a fluorescence artifact. We further show that R6A-1 has significant sequence similarity to the guanine nucleotide exchange factor peptide KB-752 that binds to switch II of G{alpha}{sub i1}. We use competitive binding analysis to show that R6A-1 also binds to switch II of G{alpha} subunits.

  16. Interested Parties - Chrystler | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    6-22-10Chrystler.pdf (38.02 KB) More Documents & Publications Interested Parties - Smith Dawson & Andrews

  17. Interested Parties - Patrick Murphy | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    S. Harris, Economic Recovery Advisor to Secretary Chu, reported contact with a lobbyists from the Free Flow Power Corporation. 04-24-2009 Registered Lobbyist Contact Disclosure Form (28.27 KB) More Documents & Publications Interested Parties - Nextfuels Interested Parties - Andrew Lundquist Interested Parties - Morgan Wright

  18. China's Pathways to Achieving 40% ~ 45% Reduction in CO{sub 2} Emissions per Unit of GDP in 2020: Sectoral Outlook and Assessment of Savings Potential

    SciTech Connect (OSTI)

    Zheng, Nina; Fridley, David; Zhou, Nan; Levine, Mark; Price, Lynn; Ke, Jing

    2011-09-30

    Achieving China’s goal of reducing its carbon intensity (CO{sub 2} per unit of GDP) by 40% to 45% percent below 2005 levels by 2020 will require the strengthening and expansion of energy efficiency policies across the buildings, industries and transport sectors. This study uses a bottom-up, end-use model and two scenarios -- an enhanced energy efficiency (E3) scenario and an alternative maximum technically feasible energy efficiency improvement (Max Tech) scenario – to evaluate what policies and technical improvements are needed to achieve the 2020 carbon intensity reduction target. The findings from this study show that a determined approach by China can lead to the achievement of its 2020 goal. In particular, with full success in deepening its energy efficiency policies and programs but following the same general approach used during the 11th Five Year Plan, it is possible to achieve 49% reduction in CO{sub 2} emissions per unit of GDP (CO{sub 2} emissions intensity) in 2020 from 2005 levels (E3 case). Under the more optimistic but feasible assumptions of development and penetration of advanced energy efficiency technology (Max Tech case), China could achieve a 56% reduction in CO{sub 2} emissions intensity in 2020 relative to 2005 with cumulative reduction of energy use by 2700 Mtce and of CO{sub 2} emissions of 8107 Mt CO{sub 2} between 2010 and 2020. Energy savings and CO{sub 2} mitigation potential varies by sector but most of the energy savings potential is found in energy-intensive industry. At the same time, electricity savings and the associated emissions reduction are magnified by increasing renewable generation and improving coal generation efficiency, underscoring the dual importance of end-use efficiency improvements and power sector decarbonization.

  19. Rate Schedules

    Broader source: Energy.gov [DOE]

    One of the major responsibilities of Southeastern is to design, formulate, and justify rate schedules. Repayment studies prepared by the agency determine revenue requirements and appropriate rate...

  20. Ethics - Conflicting Financial Interests | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Conflicting Financial Interests Ethics - Conflicting Financial Interests Suppose I don't own any shares of stock. Do I still have to think about financial conflicts of interest? You might. A Federal criminal law (18 USC 208) says that you cannot work on Government matters that will have an effect on your own personal financial interests. Stock in a company that would be affected by your job is only one example of something that could give you such an interest. For instance, you may not act on

  1. Program Evaluation: Independence, Conflict of Interest, Openness |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Planning & Conducting Evaluations » Program Evaluation: Independence, Conflict of Interest, Openness Program Evaluation: Independence, Conflict of Interest, Openness This page discusses the aspects of independence, conflict of interest, and public vs. closed sessions, in preparation for successful peer reviews. Independence The review leader and the program manager should decide at the outset the desired level of independence and the degree of external control for

  2. Aligning Utility Interests with Energy Efficiency Objectives...

    Open Energy Info (EERE)

    Interests with Energy Efficiency Objectives: A Review of Recent Efforts at Decoupling and Performance Incentives Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Aligning...

  3. DOE Affirms National Interest Electric Transmission Corridor...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    data analysis conducted in its 2006 National Interest Electric Transmission study, ... DOE also highlighted that its approach to defining the geographic boundaries of the ...

  4. Interested Parties - The Moffett Group | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    242.23 KB) More Documents & Publications Interested Parties - Accord Group Interested Parties - Myriant Interested Parties - NRG Energy

  5. Interested Parties - 1603 Program Discussion | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    1603 Program Discussion Interested Parties - 1603 Program Discussion (490.35 KB) More Documents & Publications Interested Parties - Myriant Interested Parties - NRG Energy Interested Parties - The Moffett Group

  6. Finance & Rates

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    all of its costs in the rates it charges customers for wholesale electricity and transmission services. The agency is committed to careful cost management consistent with its...

  7. Osmoregulation in Methanogens (and Other Interesting Organisms)

    SciTech Connect (OSTI)

    Roberts, Mary Fedarko

    2014-12-03

    Our research has been aimed at (i) identifying, (ii) determining mode of regulation, and (iii) understanding how different classes of compatible solutes (also termed osmolytes) affect macromolecular stability in response to osmotic and thermal stress. For solutes we have identified (e.g., di-inositol-1,1’-phosphate (DIP)), we used NMR to elucidate biosynthetic pathways and then cloned suspected enzymes in the pathway to explore how they are regulated. Compatible solutes are thought to protect proteins from thermal and osmotic stresses by being excluded from the surface, allowing critical water molecules to interact with the protein. This implies there are no specific binding interactions between osmolytes and proteins. However, we and others have often observed very specific solute effects for proteins that suggest a more direct interaction between solute and protein is likely can occur. Measuring such a weak interaction is extremely difficult. We have developed a solution NMR method, high-resolution field cycling relaxometry, that can measure spin-lattice relaxation rates as a function of magnetic field from 11.7 (the field of a 500 MHz spectrometer) to 0.003 T. The methodology is ideal for nuclei in small molecules with moderately long relaxation times at high fields – phosphate groups (31P), enriched carbonyls (13C), or methyl groups (1H). The protein of interest is spin-labeled to introduce a large dipole on it that will dominate the relaxation of nuclei on any small molecules that bind transiently. The key is to measure relaxation below 1-2 T (and extract nuclei-spin label distances in the bound complex) where the small molecule relaxation will be dominated by dipolar mechanisms with a correlation time indicative of the large protein complex. Our explorations of an inositol monophosphatase (the last step in DIP generation) localized four discrete binding sides for the thermoprotectant α-glutamate. This is a novel approach, and while the work did not fully

  8. DOE Workshop Gauges Paducah Plant Interest

    Broader source: Energy.gov [DOE]

    PADUCAH, KY – The U.S. Department of Energy’s Portsmouth/Paducah Project Office (PPPO) is completing a two-day Industry Interest Workshop today at the Julian Carroll Convention Center.

  9. Low-Interest Energy Loan Programs

    Broader source: Energy.gov [DOE]

    Loans are leveraged by utility incentives as well as federal and state tax credits and deductions. Loans are 4% interest with 5 year terms. Applications are evaluated on the basis of credit; all...

  10. DARPA Efforts and Interests in Composites

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Science Office, January,2013 or higher DoD authority DARPA Efforts and Interests in ... Science Office, January,2013 or higher DoD authority 0 400 200 Temp ( o F) Degree of ...

  11. Interested Parties - United Auto Workers | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    (860.95 KB) More Documents & Publications Interested Parties - BlueGreen Alliance Interested Parties - Myriant Interested Parties - NRG Energy

  12. Interested Parties - XtremePower | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    PDF icon 05-12-10XtremePower.pdf More Documents & Publications Interested Parties - Myriant Interested Parties - Dow Chemical Interested Parties - Shipp

  13. Power-factor metering gains new interest

    SciTech Connect (OSTI)

    Womack, D.L.

    1980-01-01

    The combined effect of increased energy costs, advances in digital metering techniques, and regulatory pressures is stimulating utility interest in charging smaller customers the full cost of their burden on the electric system, by metering reactive power and billing for poor power factor. Oklahoma Gas and Electric Co. adopted the Q-meter method, made practical with the advent of magnetic-tape metering. Digital metering and new techniques now being developed will add more options for utilities interested in metering power factor. There are three commonly used methods of determining power factor, all of which require the use of the standard induction watthour meter, plus at least one other meter, to obtain a second value in the power triangle. In all cases, the third value, if required, is obtained by calculation.

  14. Vehicle for carrying an object of interest

    DOE Patents [OSTI]

    Zollinger, W.T.; Ferrante, T.A.

    1998-10-13

    A vehicle for carrying an object of interest across a supporting surface including a frame having opposite first and second ends; a first pair of wheels fixedly mounted on the first end of the frame; a second pair of wheels pivotally mounted on the second end of the frame; and a pair of motors borne by the frame, each motor disposed in driving relation relative to one of the pairs of wheels, the motors propelling the vehicle across the supporting surface. 8 figs.

  15. Vehicle for carrying an object of interest

    DOE Patents [OSTI]

    Zollinger, W. Thor; Ferrante, Todd A.

    1998-01-01

    A vehicle for carrying an object of interest across a supporting surface including a frame having opposite first and second ends; a first pair of wheels fixedly mounted on the first end of the frame; a second pair of wheels pivotally mounted on the second end of the frame; and a pair of motors borne by the frame, each motor disposed in driving relation relative to one of the pairs of wheels, the motors propelling the vehicle across the supporting surface.

  16. DARPA Efforts and Interests in Composites

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Distribution Statement F: Further dissemination only as directed by DARPA Defense Science Office, January,2013 or higher DoD authority DARPA Efforts and Interests in Composites Michael 'Mick' Maher Briefing prepared for DOE Workshop on Low Cost Carbon Fiber January 13, 1014 3 Existing Efforts Advanced Structural Fiber * Precursor development * Process/Material Understanding * Improved properties Open Manufacturing * Technology Insertion Program * Bonded Composite Confidence *

  17. DOE Research and Development Accomplishments Interesting Insights

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DNA Interesting Insights Atom Neat Stuff a pre-Pong video game (Tennis for Two) [Video game] why dinosaurs are extinct [Alvarez] BuckyBall 'optical tweezers' [Chu] the molecule named Buckminsterfullerene (Buckyball) [Curl, Smalley] femtochemistry [Zewail] the structure of protein [Deisenhofer] the maser and the laser [Townes] Gaussian Code [Pople] biological computer modeling [Levitt] chemical computer modeling [Karplus] the Manhattan Project brings an end to World War II an anti-jet-lag diet

  18. Interested Parties - BlueGreen Alliance | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    BlueGreen Alliance Interested Parties - BlueGreen Alliance 09-25-10_Section_136_ATVM.pdf (111.58 KB) More Documents & Publications Interested Parties - MEMA Interested Parties - United Auto Workers Interested Parties - Chrystler

  19. Rates Meetings and Workshops (pbl/rates)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Rate Case Workshops Other Power Rates-Related Workshops July 1, 2004 - Rates and Finances Workshop (updated June 25, 2004) (financial and rate forecasts and scenarios for FY...

  20. Low-Interest Rates Entice Philadelphians to Reach for the Stars...

    Broader source: Energy.gov (indexed) [DOE]

    For example, "Gold Star" projects, which are guided by an energy assessment and consist of ... As an alternative to the Gold Star level, the Silver Star allows homeowners to initiate ...

  1. OM 14-66; Board's Interest Rate Remains 3 Percent for the Fourth...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    However, no case may be in the program for more than 60 days. * The preferred method of conducting settlement conferences is to have the parties or their representatives attend in ...

  2. (Expired) Nationwide Limited Public Interest Waiver for LED Lighting...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    (Expired) Nationwide Limited Public Interest Waiver for LED Lighting and HVAC Units: February 11, 2010 (Expired) Nationwide Limited Public Interest Waiver for LED Lighting and HVAC ...

  3. Home Energy Score: Program Update for Interested Stakeholders...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Score: Program Update for Interested Stakeholders Home Energy Score: Program Update for Interested Stakeholders PDF icon programupdatewebinar7-23-12.pdf More Documents & ...

  4. Financial Conflicts of Interest, Public Health Service Research...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1 Disclosure of Significant Financial Interests & Management of Financial Conflicts of Interest, Public Health Service Research Awards Effective: 082412 I. SUMMARY PURPOSE, SCOPE ...

  5. Power Rates Announcements (pbl/rates)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    WP-10 Rate Case WP-07 Rate Case WP-07 Supplemental Rate Case ASC Methodology Adjustments (2007-2009) Adjustments (2002-2006) Previous Rate Cases Financial Choices (2003-06) Power...

  6. Current BPA Power Rates (pbl/rates)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Workshops WP-10 Rate Case WP-07 Rate Case WP-07 Supplemental Rate Case ASC Methodology Adjustments (2007-2009) Adjustments (2002-2006) Previous Rate Cases Financial...

  7. Strategies for Building Contractor Interest in Program Participation |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Building Contractor Interest in Program Participation Strategies for Building Contractor Interest in Program Participation Better Buildings Residential Network Workforce / Business Partners Peer Exchange Call: Strategies for Building Contractor Interest in Program Participation, Call Slides and Summary, August 22, 2013, This workforce/business partner peer exchange call discussed strategies for building contractor interest in program participation. Call Slides and

  8. Interested Parties - Multiple Loan Applications per Developer under Section

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    1705 Program | Department of Energy Multiple Loan Applications per Developer under Section 1705 Program Interested Parties - Multiple Loan Applications per Developer under Section 1705 Program (86.96 KB) More Documents & Publications Interested Parties - Allowing Multiple Projects per Application for Section 1705 Loan Guarantees Interested Parties - K&L Group Interested Parties - Shipp

  9. Current Power Rates

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases Rate Information Current Power Rates Current Transmission Rates...

  10. Current Transmission Rates

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases Rate Information Current Power Rates Current Transmission Rates...

  11. Previous Power Rates

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases Rate Information Current Power Rates Current Transmission Rates...

  12. Previous Transmission Rates

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases Rate Information Current Power Rates Current Transmission Rates...

  13. PNCA-02 Rate Case (rates/ratecases)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Proposed Adjustment to the Rate for Interchange Energy Imbalances Under the Pacific Northwest Coordination Agreement (PNCA-02 Rate Case) (updated on April 26, 2002) BPA has issued...

  14. Interested Parties - Memo on Halting Title XVII Nuclear Loan...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Interested Parties - Memo on Halting Title XVII Nuclear Loan Guarantees in MD, SC, GA, and TX Interested Parties - Memo on Halting Title XVII Nuclear Loan Guarantees in MD, SC, GA, ...

  15. NPS Fact Sheet: Hydro-Related Roles, Interests, Activities |...

    Open Energy Info (EERE)

    Fact Sheet: Hydro-Related Roles, Interests, Activities Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: NPS Fact Sheet: Hydro-Related Roles, Interests,...

  16. Interested Parties - Smith Dawson & Andrews | Department of Energy

    Office of Environmental Management (EM)

    Smith Dawson & Andrews Interested Parties - Smith Dawson & Andrews 09-03-10SmithDawsonAndrews.pdf (37.05 KB) More Documents & Publications Interested Parties - ARPA-E National ...

  17. DOE Advisory Committee Members' Ethics and Conflict of Interest Guidance |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy DOE Advisory Committee Members' Ethics and Conflict of Interest Guidance DOE Advisory Committee Members' Ethics and Conflict of Interest Guidance DOE Advisory Committee Members' Ethics and Conflict of Interest Guidance, as posted on the U.S. Department of Energy website. Ethics and Conflict of Interest Guidance (18.43 KB) More Documents & Publications GSA Federal Advisory Committee Management; Final Rule -- 41CFR Parts 101-6 and 102-3 DOE Manual - ADVISORY COMMITTEE

  18. Interested Parties - K&L Group | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    5-26-10KLGates.pdf More Documents & Publications Interested Parties - ARPA-E National Association of Manufacturers

  19. Apparatus and method for mapping an area of interest

    DOE Patents [OSTI]

    Staab, Torsten A. Cohen, Daniel L.; Feller, Samuel

    2009-12-01

    An apparatus and method are provided for mapping an area of interest using polar coordinates or Cartesian coordinates. The apparatus includes a range finder, an azimuth angle measuring device to provide a heading and an inclinometer to provide an angle of inclination of the range finder as it relates to primary reference points and points of interest. A computer is provided to receive signals from the range finder, inclinometer and azimuth angle measurer to record location data and calculate relative locations between one or more points of interest and one or more primary reference points. The method includes mapping of an area of interest to locate points of interest relative to one or more primary reference points and to store the information in the desired manner. The device may optionally also include an illuminator which can be utilized to paint the area of interest to indicate both points of interest and primary points of reference during and/or after data acquisition.

  20. Rate Case Elements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Proceeding Rate Information Residential Exchange Program Surplus Power Sales Reports Rate Case Elements BPA's rate cases are decided "on the record." That is, in making a decision...

  1. Power Rate Cases (pbl/rates)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Choices (2003-06) Power Function Review (PFR) Firstgov Power Rate Cases BPA's wholesale power rates are set to recover its costs and repay the U.S. Treasury for the Federal...

  2. Chlorite Dissolution Rates

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Carroll, Susan

    Spreadsheets provides measured chlorite rate data from 100 to 300C at elevated CO2. Spreadsheet includes derived rate equation.

  3. Chlorite Dissolution Rates

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Carroll, Susan

    2013-07-01

    Spreadsheets provides measured chlorite rate data from 100 to 300C at elevated CO2. Spreadsheet includes derived rate equation.

  4. FY 2013 Conference Waiver - Emergency Management Issues Special Interest

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Group | Department of Energy Conference Waiver - Emergency Management Issues Special Interest Group FY 2013 Conference Waiver - Emergency Management Issues Special Interest Group FY 2013 Conference Waiver - Emergency Management Issues Special Interest Group.pdf (37.35 KB) More Documents & Publications Implementation of Division F, Title I, Title II, and Title III and Division G, Consolidated and Further Continuing Appropriations Act, 2013, Pub. L. No.113-6 Acquisition Letters No. AL

  5. Interested in joining the Workplace Charging Challenge? | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Interested in joining the Workplace Charging Challenge? Interested in joining the Workplace Charging Challenge? Thinking of joining the Workplace Charging Challenge? Tell us a little more about your organization, industry, and sustainability goals. After receiving your inquiry, one of our account managers will get back to you to discuss your eligibility and provide more information on the Challenge. Thank you for your interest! Your Email * Message Here CAPTCHA This question is for

  6. Nationwide Limited Public Interest Waiver for LED and HVAC Units |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Limited Public Interest Waiver for LED and HVAC Units Nationwide Limited Public Interest Waiver for LED and HVAC Units eere_nationwide_public_interest_waiver (55.98 KB) More Documents & Publications Nationwide Nonavailability Waiver: February 11, 2010 (Please note, the waiver for LED traffic signals has been withdrawn effective December 1, 2010) Nationwide Nonavailability Waiver: November 5, 2010 Amended Nationwide Nonavailability Waiver: November 5

  7. DOE Affirms National Interest Electric Transmission Corridor Designations |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Affirms National Interest Electric Transmission Corridor Designations DOE Affirms National Interest Electric Transmission Corridor Designations March 6, 2008 - 11:54am Addthis WASHINGTON, DC - The U.S. Department of Energy (DOE) today denied requests for rehearing of the Mid-Atlantic and the Southwest Area National Interest Electric Transmission Corridors (National Corridors) designated by DOE in October 2007 as areas of significant electricity congestion and constraint.

  8. DOE Seeks Expression of Interest for Carlsbad Technical Support Services |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Expression of Interest for Carlsbad Technical Support Services DOE Seeks Expression of Interest for Carlsbad Technical Support Services July 10, 2014 - 12:00pm Addthis Media Contact Lynette Chafin, 513-246-0461, Lynette.Chafin@emcbc.doe.gov Cincinnati - The U.S. Department of Energy (DOE) Environmental Management Consolidated Business Center (EMCBC) today issued a Sources Sought Synopsis/Expression of Interest seeking small business concerns with the capabilities to

  9. Ames Laboratory Conflict of Interest Policy | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ames Laboratory Conflict of Interest Policy The Ames Laboratory has developed a conflict of interest and consulting policy for Laboratory employees. The Policy is more stringent than Iowa State University's (Laboratory Contractor) policy as a result of integrating requirements stipulated in the University's contract with the Department of Energy (DE-AC02-07CH11358) with the University's conflict of interest policies. Please take time to review the policy to make sure you are complying with its

  10. Interested Parties - Allowing Multiple Projects per Application for Section

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    1705 Loan Guarantees | Department of Energy Allowing Multiple Projects per Application for Section 1705 Loan Guarantees Interested Parties - Allowing Multiple Projects per Application for Section 1705 Loan Guarantees Multiple_Projects_Section_1705_Loan_Guarantees.pdf (24.78 KB) More Documents & Publications Interested Parties - Multiple Loan Applications per Developer under Section 1705 Program Interested Parties - K&L Group Lobbyist Disclosure Form - John Thorne

  11. Strategies for Building Contractor Interest in Program Participation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Strategies for Building Contractor Interest in Program Participation Better Buildings Residential Network Workforce Business Partners Peer Exchange Call: Strategies for Building ...

  12. Integration of Renewables and Efficiency: Leveraging Interest and Funding

    Broader source: Energy.gov [DOE]

    This webinar, held on Feb. 17, 2011, focuses on leveraging interest and funding to implement energy efficiency and renewable energy technologies.

  13. Home Energy Score: Program Update for Interested Stakeholders...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Home Energy Score: Program Update for Interested Stakeholders, a presentation by the U.S. Department of Energy, Home Energy Score program, from Joan Glickman, Senior Advisor...

  14. National Interest Security Company NISC Formerly Technology Management...

    Open Energy Info (EERE)

    NISC Formerly Technology Management Services TMS Inc Jump to: navigation, search Name: National Interest Security Company (NISC) (Formerly Technology & Management Services (TMS)...

  15. UC Center for Information Technology Research in the Interest...

    Open Energy Info (EERE)

    Center for Information Technology Research in the Interest of Society (CITRIS) Place: Berkeley, California Zip: 94720 Region: Bay Area Website: www.citris-uc.org Coordinates:...

  16. Low Interest Energy Efficiency Loan Program (Electric and Gas)

    Office of Energy Efficiency and Renewable Energy (EERE)

    Energize CT offers low interest loans for commercial and industrial customers for investments in energy efficiency improvements. Electric customers of Connecticut Light & Power, United...

  17. Before a Rate Case

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases BP-18 Rate Case Related Publications Meetings and Workshops Customer...

  18. Rating Agency Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Liabilities Financial Plan Financial Public Processes Asset Management Cost Verification Process Rate Cases Rate Information Residential Exchange Program Surplus Power Sales...

  19. 2012 Transmission Rate Schedules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2014 Transmission, Ancillary, and Control Area Service Rate Schedules and General Rate Schedule Provisions (FY 2014-2015) October 2013 United States Department of Energy...

  20. BP-18 Rate Proceeding

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Skip navigation links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases BP-18 Rate Case Related Publications Meetings...

  1. BP-12 Rate Case

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Skip navigation links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases BP-18 Rate Case Related Publications Meetings...

  2. BP-16 Rate Case

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Skip navigation links Financial Information Financial Public Processes Asset Management Cost Verification Process Rate Cases BP-18 Rate Case Related Publications Meetings...

  3. Broad area search for regions and objects of interest

    SciTech Connect (OSTI)

    Skurikhin, Alexei N; Pope, Paul A

    2011-01-12

    A quad chart provides an overview on the on-going project 'Broad Area Search for Regions and Objects of Interest' funded by the DOE Office of Nonproliferation and Verification Research and Development. Specifically, the quad chart shows: (1) Project title 'Broad Area Search for Regions and Objects of Interest'; (2) PI and Co-investigators; (3) Concept Panel outlining the project's approach built upon front-end scale-space image analysis; (4) Technical Challenges posed by the project, such as robustness, non-conformities, disparate spatial configuration and weak correlation between presence of objects of interest and low-level description of the surrounding geospatial background; and (5) Planned Accomplishment.

  4. Home Energy Score: Program Update for Interested Stakeholders

    Broader source: Energy.gov [DOE]

    Home Energy Score: Program Update for Interested Stakeholders, a presentation by the U.S. Department of Energy, Home Energy Score program, from Joan Glickman, Senior Advisor/Program Manager, July 23, 2012.

  5. Geothermal, the 'undervalued' renewable resource, sees surging interest |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Geothermal, the 'undervalued' renewable resource, sees surging interest Geothermal, the 'undervalued' renewable resource, sees surging interest May 21, 2009 - 10:38am Addthis Nearly 200 million acres of public lands, mostly in the West, could become prime generators of emissions-free electricity by extracting steam heat from the earth's core to drive electric turbines. Yet despite a $400 million stimulus bill allocation to spur geothermal energy production in the United

  6. DOE National Analytical Management Program Draws Global Interest |

    Office of Environmental Management (EM)

    Department of Energy National Analytical Management Program Draws Global Interest DOE National Analytical Management Program Draws Global Interest February 27, 2013 - 12:00pm Addthis Hnin Khaing focuses on her work at WIPP Laboratories near Carlsbad, New Mexico Hnin Khaing focuses on her work at WIPP Laboratories near Carlsbad, New Mexico Corey White works at WIPP Laboratories near Carlsbad, New Mexico Corey White works at WIPP Laboratories near Carlsbad, New Mexico Hnin Khaing focuses on

  7. DOE Advisory Committee Members' Ethics and Conflict of Interest Guidance

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ETHICS AND CONFLICT OF INTEREST GUIDANCE for Department of Energy Advisory Committee Members The composition of the Department's advisory committees may include both full-time Federal Government employees and individuals who are employed by or represent non- Federal Government entities. Members of a committee who represent interests other than the Federal Government are not Government employees or so-called "special Government employees." For non-Federal advisory committee members, the

  8. Home Energy Score: Information for Interested Organizations | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Organizations Home Energy Score: Information for Interested Organizations Home Energy Score Partners include various types of organizations (e.g., utilities, state agencies, local governments, non-profits, contractor associations) that administer the delivery of the Score on a local, state, or national basis. Partners must be able to score at least 500 homes a year and fulfill quality assurance requirements in order to participate in the program. If your organization is interested in

  9. The conflict of interest problem in EIS preparation

    SciTech Connect (OSTI)

    Hansen, R.P. [Hansen Environmental Consultants, Englewood, CO (United States); Wolff, T.A. [Sandia National Labs., Albuquerque, NM (United States); McCold, L.N. [Oak Ridge National Lab., TN (United States)

    1997-05-01

    The National Environmental Policy Act (NEPA) requires that federal agencies prepare environmental impact statements (EISs) on proposals for major Federal action significantly affecting the quality of the human environment. The Council on Environmental Quality (CEQ) regulations require that EISs be prepared directly by the lead agency or a contractor it selects. EIS contractors must execute a disclosure statement specifying that they have ``no financial or other interest`` in the outcome of the project. The intent of the ``conflict of interest`` prohibition is to ensure that the EIS is defensible, free of self-serving bias, and credible to the public. Those coming to the federal government for money, permits, or project approvals must not be placed in the position of analyzing the environmental consequences of their own proposals. This paper analyzes the conflict of interest problem faced by government contractors who maintain and operate government-owned or-controlled facilities for which EISs are required. In the US Department of Energy (DOE) system, these are referred to as ``M and O`` contractors. It also examines organizational conflicts presented by current or prospective government contractors who have a financial or other interest in the outcome of a project or program for which an EIS is prepared. In responding to these and related questions, the paper discusses and interprets the CEQ regulations and guidance on EIS preparation conflict of interest as well as leading federal court opinions. It also distinguishes ``preparers`` from ``participants`` in the EIS preparation process.

  10. Binary classification of items of interest in a repeatable process

    SciTech Connect (OSTI)

    Abell, Jeffrey A.; Spicer, John Patrick; Wincek, Michael Anthony; Wang, Hui; Chakraborty, Debejyo

    2014-06-24

    A system includes host and learning machines in electrical communication with sensors positioned with respect to an item of interest, e.g., a weld, and memory. The host executes instructions from memory to predict a binary quality status of the item. The learning machine receives signals from the sensor(s), identifies candidate features, and extracts features from the candidates that are more predictive of the binary quality status relative to other candidate features. The learning machine maps the extracted features to a dimensional space that includes most of the items from a passing binary class and excludes all or most of the items from a failing binary class. The host also compares the received signals for a subsequent item of interest to the dimensional space to thereby predict, in real time, the binary quality status of the subsequent item of interest.

  11. Recommending personally interested contents by text mining, filtering, and interfaces

    SciTech Connect (OSTI)

    Xu, Songhua

    2015-10-27

    A personalized content recommendation system includes a client interface device configured to monitor a user's information data stream. A collaborative filter remote from the client interface device generates automated predictions about the interests of the user. A database server stores personal behavioral profiles and user's preferences based on a plurality of monitored past behaviors and an output of the collaborative user personal interest inference engine. A programmed personal content recommendation server filters items in an incoming information stream with the personal behavioral profile and identifies only those items of the incoming information stream that substantially matches the personal behavioral profile. The identified personally relevant content is then recommended to the user following some priority that may consider the similarity between the personal interest matches, the context of the user information consumption behaviors that may be shown by the user's content consumption mode.

  12. Recommending personally interested contents by text mining, filtering, and interfaces

    DOE Patents [OSTI]

    xu, Songhua

    2015-11-05

    A personalized content recommendation system includes a client interface device configured to monitor a user's information data stream. A collaborative filter remote from the client interface device generates automated predictions about the interests of the user. A database server stores personal behavioral profiles and user's preferences based on a plurality of monitored past behaviors and an output of the collaborative user personal interest inference engine. A programmed personal content recommendation server filters items in an incoming information stream with the personal behavioral profile and identifies only those items of the incoming information stream that substantially matches the personal behavioral profile. The identified personally relevant content is then recommended to the user following some priority that may consider the similarity between the personal interest matches, the context of the user information consumption behaviors that may be shown by the user's content consumption mode.

  13. Calling All Majors: Sparking Clean Energy Interest from Students in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Washington | Department of Energy Calling All Majors: Sparking Clean Energy Interest from Students in Washington Calling All Majors: Sparking Clean Energy Interest from Students in Washington November 6, 2014 - 3:55pm Addthis Students in Western Washington University’s spring 2013 “Applications in Energy Production” course get an up-close view of how energy is generated. | Photo: Courtesy of Chris Linder, Western Washington University. Students in Western Washington

  14. Interested in Open Energy Data? Watch the Energy Datapalooza Live! |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Interested in Open Energy Data? Watch the Energy Datapalooza Live! Interested in Open Energy Data? Watch the Energy Datapalooza Live! September 27, 2012 - 5:25pm Addthis U.S. Chief Technology Officer Todd Park kicks off the Safety Datapalooza on September 19th. | Photo Courtesy U.S. Department of Labor U.S. Chief Technology Officer Todd Park kicks off the Safety Datapalooza on September 19th. | Photo Courtesy U.S. Department of Labor Matthew Loveless Matthew Loveless

  15. Home Energy Score: Information for Interested Assessors | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Assessors Home Energy Score: Information for Interested Assessors <a target="_self" href="/node/1014056">Read DOE's announcement about the new training and tool that broadens the pool of individuals qualified to provide the Home Energy Score.</a> Read DOE's announcement about the new training and tool that broadens the pool of individuals qualified to provide the Home Energy Score. Interested in Becoming a Home Energy Score Assessor? Follow these steps

  16. DOE Issues Two Draft National Interest Electric Transmission Corridor Designations

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy (DOE) Secretary Samuel W. Bodman today announced the issuance of two draft National Interest Electric Transmission Corridor (National Corridor) designations. The Energy Policy Act of 2005 authorizes the Secretary, based on the findings of DOE's National Electric Transmission Congestion Study (Congestion Study), to designate National Corridors.

  17. Final Report - National Database of Utility Rates and Rate Structure...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    National Database of Utility Rates and Rate Structure Final Report - National Database of Utility Rates and Rate Structure Awardee: Illinois State University Location: Normal, IL ...

  18. Resonant thermonuclear reaction rate

    SciTech Connect (OSTI)

    Haubold, H.J.; Mathai, A.M.

    1986-08-01

    Basic physical principles for the resonant and nonresonant thermonuclear reaction rates are applied to find their standard representations for nuclear astrophysics. Closed-form representations for the resonant reaction rate are derived in terms of Meijer's G-italic-function. Analytic representations of the resonant and nonresonant nuclear reaction rates are compared and the appearance of Meijer's G-italic-function is discussed in physical terms.

  19. Improving Entrainment Rate Parameterization

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Entrainment Rate Parameterization For original submission and image(s), see ARM Research Highlights http://www.arm.gov/science/highlights/ Research Highlight Parameterization of entrainment rate is critical for improving representation of cloud- and convection-related processes in climate models; however, much remains unclear. This work seeks to improve understanding and parameterization of entrainment rate by use of aircraft observations and large-eddy simulations of shallow cumulus clouds over

  20. Draft Tiered Rate Methodology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    For Regional Dialogue Discussion Purposes Only Pre-Decisional Draft Tiered Rates Methodology March 7, 2008 Pre-decisional, Deliberative, For Discussion Purposes Only March 7,...

  1. LCC Guidance Rates

    Broader source: Energy.gov [DOE]

    Notepad text file provides the LCC guidance rates in a numbered format for the various regions throughout the U.S.

  2. Binary classification of items of interest in a repeatable process

    DOE Patents [OSTI]

    Abell, Jeffrey A; Spicer, John Patrick; Wincek, Michael Anthony; Wang, Hui; Chakraborty, Debejyo

    2015-01-06

    A system includes host and learning machines. Each machine has a processor in electrical communication with at least one sensor. Instructions for predicting a binary quality status of an item of interest during a repeatable process are recorded in memory. The binary quality status includes passing and failing binary classes. The learning machine receives signals from the at least one sensor and identifies candidate features. Features are extracted from the candidate features, each more predictive of the binary quality status. The extracted features are mapped to a dimensional space having a number of dimensions proportional to the number of extracted features. The dimensional space includes most of the passing class and excludes at least 90 percent of the failing class. Received signals are compared to the boundaries of the recorded dimensional space to predict, in real time, the binary quality status of a subsequent item of interest.

  3. Protection and Control of Safeguards and Security Interests

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1994-07-15

    To establish policy, responsibilities, and authorities for the protection and control of safeguards and security interests. Cancels DOE O 5632.1B, DOE O 5632.2A, DOE O 5632.5, DOE O 5632.6, DOE O 5632.9A, DOE O 5632.11, DOE O 5635.1A, DOE O 5635.2B, DOE O 5635.3. Canceled by DOE O 473.1

  4. Home Energy Score: Program Update for Interested Stakeholders

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Home Energy Score: Program Update for Interested Stakeholders Joan Glickman Senior Advisor/Program Manager U.S. Department of Energy July 23, 2012 1 eere.energy.gov DOE's objectives for the Home Energy Score Program * Strengthen the home energy improvement market * Provide an affordable and credible means for homeowners to understand - their home's energy performance, - how their home compares to others in their area, and - how to improve its efficiency. * Build on and complement existing home

  5. Hour of Code sparks interest in computer science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM skills Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue: September 1, 2016 all issues All Issues » submit Hour of Code sparks interest in computer science Taking the mystery out of programming February 1, 2016 Hour of Code participants work their way through fun computer programming tutorials. Hour of Code participants work their way through fun computer programming tutorials. Contacts Community Programs Director Kathy Keith Email

  6. JBEI Research Receives Strong Industry Interest in DOE Technology Transfer

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Call Research Receives Strong Industry Interest in DOE Technology Transfer Call - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing

  7. Rating fenestration for energy efficiency

    SciTech Connect (OSTI)

    Markway, R.

    1993-09-01

    The grading of windows and doors by the National Fenestration Rating Council (NFRC) opens a new era regarding the energy efficiency of fenestration products. For the first time, architects, designers, and other specifiers will find themselves on a level playing field when it comes to comparing the thermal performance of fenestration products. Although only one state, California, now requires the use of fenestration products that have gone through the NFRC's simulation and testing procedures, five other states will soon be doing so, including Washington, Alaska, Oregon, Idaho, and Wisconsin. Others will follow suit; Florida, Arizona, Texas, Louisiana, New York, Massachusetts, and Colorado have shown interest. Exactly what does this mean to architects The NFRC, which was established last year, has developed a procedure to determine accurately the U-value of fenestration products. Under the NFRC program a number of independent simulation and testing laboratories have been approved. These laboratories are charged with the responsibility of determining whether products conform to the U-values represented by the manufacturers. The rating procedure and benefits from it are described.

  8. To Persons Interested in the BPA 2008 Resource Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the BPA Resource Program. We will keep in touch with you as we analyze BPA's future resource needs. Sincerely, s Suzanne B. Cooper April 3, 2008 Manager, Power Policy and Rates...

  9. Other Major Litigation of Direct Interest to DOE

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2008 Other Major Litigation of Direct Interest to DOE Entergy Corporation v. EPA; PSEG Fossil LLC v. Riverkeeper, Inc.; Utility Water Group v. Riverkeeper, Inc., S. Ct. Nos. 07-588, 07-589, and 07-597. The question presented in this litigation is whether Section 316(b) of the Clean Water Act, 33 U.S.C. 1326(b), authorizes EPA to compare costs and benefits in determining the "best technology available for minimizing adverse environmental impact" at cooling water intake structures. The

  10. The private sector: Cautiously interested in distribution in India

    SciTech Connect (OSTI)

    Banks, J.P.; Bowman, C.D.; Guy, J.; Gross, T.P.

    1998-06-01

    As privatization and liberalization proceed in India--the world`s second largest growth market for electricity--sensible experimentation by the states on the rules of the game is vital. A new joint venture approach in Rajasthan may be a helpful model. This article provides an overview of the principal challenges confronting US utilities interested in investing in distribution in India as well as a summary of two mechanisms developed to facilitate private investment. These challenges also should be considered in view of the changing political conditions in India owing to the recent election of the coalition government led by the Bharatiya Janata Party.

  11. Young Women's Conference cheers on girls interested in STEM | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab Young Women's Conference cheers on girls interested in STEM By Jeanne Jackson DeVoe March 27, 2014 Tweet Widget Google Plus One Share on Facebook PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's Conference on March 21 at Princeton University. (Photo by Elle Starkman/ PPPL Office of Communications) PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's

  12. Young Women's Conference cheers on girls interested in STEM | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab Young Women's Conference cheers on girls interested in STEM By Jeanne Jackson DeVoe March 28, 2014 Tweet Widget Google Plus One Share on Facebook PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's Conference on March 21. (Photo by Elle Starkman/ PPPL Office of Communications) PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's Conference on March 21.

  13. Pitfalls of preparing deeds conveying oil and gas interests

    SciTech Connect (OSTI)

    Hawkins, E.G.

    1986-01-01

    A sudden increase in legal activity involving the preparation or review of deeds to oil and gas interests is the result of expanded exploration and development activities in Alabama. Because of the complexities of an oil or gas transaction and the presence of title defects, there are legal problems which are unique to these cases. The author highlights some of the more common problems and defects, and recommends ways for lawyers to avoid them. The discussion touches on the mineral deed versus the royalty deed, conflicts over the mineral acre versus the fractional grant, the rule against perpetuities, roadways, and other problems.

  14. Packaging and Transfer of Materials of National Security Interest Manual

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2000-09-29

    This Technical Manual establishes requirements for operational safety controls for onsite operations and provides Department of Energy (DOE) technical safety requirements and policy objectives for development of an Onsite Packaging and Transfer Program, pursuant to DOE O 461.1A, Packaging and Transfer or Transportation of Materials of National Security Interest. The DOE contractor must document this program in its Onsite Packaging and Transfer Manual/Procedures. Admin Chg 1, 7-26-05. Certified 2-2-07. Canceled by DOE O 461.2.

  15. Best Practices: Escalation Rates

    Office of Environmental Management (EM)

    Best Practices Escalation Rates Hosted by: FEDERAL UTILITY PARTNERSHIP WORKING GROUP SEMINAR November 3-4, 2015 Houston, TX Federal Utility Partnership Working Group November 3-4, 2015 Houston, TX Federal Utility Partnership Working Group November 3-4, 2015 Houston, TX Best Practices: Escalation Rate Value of future energy savings * Provides purchasing power for implementing a robust, comprehensive and customized ECM set * Provides an option for paying back financing in the shortest possible

  16. 2007-2009 Power Rate Adjustments (pbl/rates)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Function Review (PFR) Firstgov FY 2007 2009 Power Rate Adjustments BPA's 2007-2009 Wholesale Power Rate Schedules and General Rate Schedule Provisions (GRSPs) took effect on...

  17. WP-07 Power Rate Case (rates/ratecases)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Meetings & Workshops Rate Case Parties Web Site WP-07 Supplemental Rate Case ASC Methodology Adjustments (2007-2009) Adjustments (2002-2006) Previous Rate Cases Financial...

  18. Factors that Determine Academic Versus Private Practice Career Interest in Radiation Oncology Residents in the United States: Results of a Nationwide Survey

    SciTech Connect (OSTI)

    Chang, Daniel T.; Shaffer, Jenny L.; Haffty, Bruce G.; Wilson, Lynn D.

    2013-11-01

    Purpose: To determine what factors US radiation oncology residents consider when choosing academic or nonacademic careers. Methods and Materials: A 20-question online survey was developed and sent to all US radiation oncology residents to assess factors that influence their career interest. Residents were asked to rate their interest in academics (A) versus private practice (PP) on a 0 (strong interest in A) to 100 (strong interest in PP) scale. Responses were classified as A (0-30), undecided (40-60), and PP (70-100). Residents were also asked to rank 10 factors that most strongly influenced their career interest. Results: Three hundred thirty-one responses were collected, of which 264 were complete and form the basis for this analysis. Factors that correlated with interest in A included having a PhD (P=.018), postgraduate year level (P=.0006), research elective time (P=.0003), obtaining grant funding during residency (P=.012), and number of publications before residency (P=.0001), but not number of abstracts accepted in the past year (P=.65) or publications during residency (P=.67). The 3 most influential factors for residents interested in A were: (1) baseline interest before residency; (2) academic role models; and (3) research opportunities during residency. The 3 most influential factors for residents interested in PP were: (1) baseline interest before residency; (2) academic role models; and (3) academic pressure and obligations. Conclusions: Interest in A correlated with postgraduate year level, degree, and research time during residency. Publications before but not during residency correlated with academic interest, and baseline interest was the most influential factor. These data can be used by residency program directors to better understand what influences residents' career interest.

  19. Adaptive optics images. III. 87 Kepler objects of interest

    SciTech Connect (OSTI)

    Dressing, Courtney D.; Dupree, Andrea K.; Adams, Elisabeth R.; Kulesa, Craig; McCarthy, Don

    2014-11-01

    The Kepler mission has revolutionized our understanding of exoplanets, but some of the planet candidates identified by Kepler may actually be astrophysical false positives or planets whose transit depths are diluted by the presence of another star. Adaptive optics images made with ARIES at the MMT of 87 Kepler Objects of Interest place limits on the presence of fainter stars in or near the Kepler aperture. We detected visual companions within 1'' for 5 stars, between 1'' and 2'' for 7 stars, and between 2'' and 4'' for 15 stars. For those systems, we estimate the brightness of companion stars in the Kepler bandpass and provide approximate corrections to the radii of associated planet candidates due to the extra light in the aperture. For all stars observed, we report detection limits on the presence of nearby stars. ARIES is typically sensitive to stars approximately 5.3 Ks magnitudes fainter than the target star within 1'' and approximately 5.7 Ks magnitudes fainter within 2'', but can detect stars as faint as ΔKs = 7.5 under ideal conditions.

  20. Sequoia Messaging Rate Benchmark

    Energy Science and Technology Software Center (OSTI)

    2008-01-22

    The purpose of this benchmark is to measure the maximal message rate of a single compute node. The first num_cores ranks are expected to reside on the 'core' compute node for which message rate is being tested. After that, the next num_nbors ranks are neighbors for the first core rank, the next set of num_nbors ranks are neighbors for the second core rank, and so on. For example, testing an 8-core node (num_cores = 8)more » with 4 neighbors (num_nbors = 4) requires 8 + 8 * 4 - 40 ranks. The first 8 of those 40 ranks are expected to be on the 'core' node being benchmarked, while the rest of the ranks are on separate nodes.« less

  1. DOE Seeks Public-Private Sector Expressions of Interest for Global...

    Office of Environmental Management (EM)

    Public-Private Sector Expressions of Interest for Global Nuclear Energy Partnership Initiative DOE Seeks Public-Private Sector Expressions of Interest for Global Nuclear Energy ...

  2. Residential Solar Valuation Rates

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Valuation Rates Karl R. Rábago Rábago Energy LLC 1 The Ideal Residential Solar Tariff ‣ Fair to the utility and non-solar customers ‣ Fair compensation to the solar customer ‣ Decouple compensation from incentives ‣ Align public policy goals (decouple compensation from consumption) ‣ Intuitively sound and administratively simple 2 Historical Antecedents ‣ Externalities ‣ Price ≠ Cost ‣ Green Power ‣ Small Is Profitable (http://www.smallisprofitable.org/) ‣ Local

  3. Rotational rate sensor

    DOE Patents [OSTI]

    Hunter, Steven L. (Livermore, CA)

    2002-01-01

    A rate sensor for angular/rotational acceleration includes a housing defining a fluid cavity essentially completely filled with an electrolyte fluid. Within the housing, such as a toroid, ions in the fluid are swept during movement from an excitation electrode toward one of two output electrodes to provide a signal for directional rotation. One or more ground electrodes within the housing serve to neutralize ions, thus preventing any effect at the other output electrode.

  4. Writing Effective Initial Summary Ratings Initial Summary Rating...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Initial Summary Ratings Initial Summary Rating (ISR) At the end of the performance cycle, the rating official must prepare an ISR in ePerformance for each SES member who has ...

  5. Writing Effective Initial Summary Ratings Initial Summary Rating (ISR)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Initial Summary Ratings Initial Summary Rating (ISR) At the end of the performance cycle, the rating official must prepare an ISR in ePerformance for each SES member who has completed at least 90 days on an established performance plan. Rating officials must take into account the SES member's accomplishments achieved during the performance cycle and the impact to the organization's performance. Rating officials must appraise executives realistically and fairly and avoid ratings inflation.

  6. October 1996 - September 2001 Wholesale Power Rates (rates/previous...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    affecting a specific power purchase. For more specific information see: 1996 Final Wholesale Power and Transmission Rate Schedules: Power Rates (PDF, 84 pages, 188 kb) Ancillary...

  7. PULSE RATE DIVIDER

    DOE Patents [OSTI]

    McDonald, H.C. Jr.

    1962-12-18

    A compact pulse-rate divider circuit affording low impedance output and high input pulse repetition rates is described. The circuit features a single secondary emission tube having a capacitor interposed between its dynode and its control grid. An output pulse is produced at the anode of the tube each time an incoming pulse at the control grid drives the tube above cutoff and the duration of each output pulse corresponds to the charging time of the capacitor. Pulses incoming during the time the grid bias established by the discharging capacitor is sufficiently negative that the pulses are unable to drive the tube above cutoff do not produce output pulses at the anode; these pulses are lost and a dividing action is thus produced by the circuit. The time constant of the discharge path may be vanied to vary in turn the division ratio of the circuit; the time constant of the charging circuit may be varied to vary the width of the output pulses. (AEC)

  8. Property:OpenEI/UtilityRate/EnergyRateStructure/Tier5Rate | Open...

    Open Energy Info (EERE)

    Property Edit with form History Facebook icon Twitter icon Property:OpenEIUtilityRateEnergyRateStructureTier5Rate Jump to: navigation, search This is a property of type...

  9. Property:OpenEI/UtilityRate/DemandRateStructure/Tier1Rate | Open...

    Open Energy Info (EERE)

    Property Edit with form History Facebook icon Twitter icon Property:OpenEIUtilityRateDemandRateStructureTier1Rate Jump to: navigation, search This is a property of type...

  10. Property:OpenEI/UtilityRate/DemandRateStructure/Tier3Rate | Open...

    Open Energy Info (EERE)

    Property Edit with form History Facebook icon Twitter icon Property:OpenEIUtilityRateDemandRateStructureTier3Rate Jump to: navigation, search This is a property of type...

  11. Property:OpenEI/UtilityRate/EnergyRateStructure/Tier3Rate | Open...

    Open Energy Info (EERE)

    Property Edit with form History Facebook icon Twitter icon Property:OpenEIUtilityRateEnergyRateStructureTier3Rate Jump to: navigation, search This is a property of type...

  12. Property:OpenEI/UtilityRate/EnergyRateStructure/Tier4Rate | Open...

    Open Energy Info (EERE)

    Property Edit with form History Facebook icon Twitter icon Property:OpenEIUtilityRateEnergyRateStructureTier4Rate Jump to: navigation, search This is a property of type...

  13. WP-02 Power Rate Case (rates/ratecases)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    WP-02 Power Rate Case (Updated on May 7, 2004) In May of 2000, the BPA Administrator signed a Record of Decision (ROD) on the 2002 Final Power Rate Proposal for the October 2001...

  14. 2007-2009 Power Rates Quarterly Updates (pbl/rates)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (PFR) Firstgov FY 2007 2009 Power Rates Quarterly Updates In BPAs 2007-2009 Wholesale Power Rate Case (WP-07), BPA agreed that it would post reports about BPAs power...

  15. October 2005 - March 2006 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 30.56% non-Slice LB + FB + SN CRAC adjustment for each month of the six-month rate period. The table below...

  16. April - September 2002 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 40.77% non-Slice LB CRAC adjustment for each month of the six-month rate period. The table below is simply a...

  17. October 2004 - March 2005 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The PDF documents above provide tables of monthly Slice, PF, RL, and IP rates with the LB + FB + SN CRAC adjustments for each month of the rate period. The table below is simply...

  18. April - September 2005 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 36.93% non-Slice LB + FB + SN CRAC adjustment for each month of the six-month rate period. The table below...

  19. October 2003 - March 2004 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 43.66% non-Slice LB + FB + SN CRAC adjustment for each month of the rate period. The table below is simply a...

  20. October 2002 - March 2003 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 43.91% non-Slice LB + FB CRAC adjustment for each month of the six-month rate period. The table below is...

  1. October 2001 - March 2002 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 46% non-Slice LB CRAC adjustment for each month of the six-month rate period. The table below is simply a...

  2. April - September 2003 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 49.50% non-Slice LB + FB CRAC adjustment for each month of the six-month rate period. The table below is...

  3. April - September 2004 Power Rates (rates/previous)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    above provides a table of monthly Slice, PF, RL, and IP rates with a 47.00% non-Slice LB + FB + SN CRAC adjustment for each month of the six-month rate period. The table below...

  4. FPS-96R Rate Adjustment (rates/ratecases)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Final Firm Power Products and Services (FPS-96R) Rate Adjustment In August 1999, BPA proposed to correct errors in the Firm Power Products and Services rate schedule (FPS-96), and...

  5. Alaska Oil and Gas Finding of Best Interest | Open Energy Information

    Open Energy Info (EERE)

    Oil and Gas Finding of Best Interest Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Alaska Oil and Gas Finding of Best Interest Author Alaska...

  6. National Utility Rate Database: Preprint

    SciTech Connect (OSTI)

    Ong, S.; McKeel, R.

    2012-08-01

    When modeling solar energy technologies and other distributed energy systems, using high-quality expansive electricity rates is essential. The National Renewable Energy Laboratory (NREL) developed a utility rate platform for entering, storing, updating, and accessing a large collection of utility rates from around the United States. This utility rate platform lives on the Open Energy Information (OpenEI) website, OpenEI.org, allowing the data to be programmatically accessed from a web browser, using an application programming interface (API). The semantic-based utility rate platform currently has record of 1,885 utility rates and covers over 85% of the electricity consumption in the United States.

  7. WPN 12-10: Guidance for Returning Interest Earned | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    10: Guidance for Returning Interest Earned WPN 12-10: Guidance for Returning Interest Earned Archived, One-Time Occurrence To provide guidance on options available for Grantees and Recipients returning interest earned on advanced federal funds under the U.S. Department of Energy (DOE) Weatherization Assistance Program (WAP). WPN 12-10: Guidance for Returning Interest Earned (123.12 KB) More Documents & Publications State Energy Program and Energy Efficiency and Conservation Block Grant

  8. Project Definition Rating Index Workbook

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Project Definition Rating Index (PDRI) Workbook is a tool that was developed to support DOE G-413.3-12A, U. S. Department of Energy Project Definition Rating Index Guide for Traditional Nuclear...

  9. SN-03 Rate Case Workshops (rates/meetings)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Materials Related Link: SN-03 Power Rate Case May 1 & 13, 2003 - Debt and Liquidity Strategies workshops (on BPA Corporate web site) March 27, 2003 - SN CRAC Prescheduling...

  10. What Is the Right Rate? Loan Rates and Demand

    Broader source: Energy.gov [DOE]

    Better Buildings Neighborhood Program Financing Peer Exchange Call: “What is the Right Rate?” call slides and discussion summary, December 1, 2011.

  11. ARM - Measurement - Radiative heating rate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    govMeasurementsRadiative heating rate ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Radiative heating rate The heating rate due to the divergence of long and shortwave radiative flux. Categories Radiometric, Atmospheric State Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a

  12. Wholesale Power Rate Schedules | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Rate Schedules Wholesale Power Rate Schedules Wholesale Power Rate Schedules October 1, 2012 ALA-1-N Wholesale Power Rate Schedule Area: PowerSouth Energy Cooperative System:...

  13. Sustainable Building Rating Systems Summary

    SciTech Connect (OSTI)

    Fowler, Kimberly M.; Rauch, Emily M.

    2006-07-01

    The purpose of this document is to offer information that could be used to compare and contrast sustainable building rating systems.

  14. Rate Schedules | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Repayment studies prepared by the agency determine revenue requirements and appropriate rate levels and these studies for each of Southeastern's four power marketing systems are ...

  15. Conflict-of-Interest/Non-Disclosure Certificate For Reviewers Involved in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Selection of Subcontractors for NEUP Research and Development Funds | Department of Energy Conflict-of-Interest/Non-Disclosure Certificate For Reviewers Involved in the Selection of Subcontractors for NEUP Research and Development Funds Conflict-of-Interest/Non-Disclosure Certificate For Reviewers Involved in the Selection of Subcontractors for NEUP Research and Development Funds The Department of Energy has a policy that individuals with a conflict of interest cannot participate in the

  16. DOE Seeks Public-Private Sector Expressions of Interest for Global Nuclear

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Partnership Initiative | Department of Energy Public-Private Sector Expressions of Interest for Global Nuclear Energy Partnership Initiative DOE Seeks Public-Private Sector Expressions of Interest for Global Nuclear Energy Partnership Initiative March 17, 2006 - 3:46pm Addthis WASHINGTON, DC - U.S. Secretary of Energy Samuel Bodman today announced that the Department of Energy (DOE) is seeking expressions of interest from the public and private sectors by March 31, 2006, to propose

  17. Paper on "Other Major Litigation of Direct Interest to DOE"

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NOTE TO: Cynthia L. Quarterman Department of Energy Agency Review Team FROM: Janet Z. Barsy Qi Special AssistantO ffice of the General Counsel SUBJECT: Paper on "Other Major Litigation of Direct Interest to DOE" DATE: December 5, 2008 At our meeting on November 24, 2008, you expressed an interest in major litigation of direct interest to the Department where DOE has an interest in the outcome of the suit although it is not a party to the litigation. Attached is a paper prepared by the

  18. BPA revises oversupply rate proposal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    comments until May 22, 2013. The rate-setting process will end with the administrator making a decision based on the record developed in the case. BPA expects to issue a final...

  19. Tier 2 Vintage Rate Workshop

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    at a Tier 2 rate 3) Combination of the two On Nov 1, 2009, customers made their elections for how they will serve their Above-RHWM Load during the FY 2012-2014 purchase...

  20. DOE Guidance-Category Rating

    Broader source: Energy.gov (indexed) [DOE]

    August 27, 2010 MEMORANDUM FOR HUMAN RESOURCES DIRECTORS FROM: SARA"iJ. Boku1, DIRECToR OF HUMAN CTAL MANAGEMENT SUBJECT: GUIDANCE MEMORANDUM 10 CATEGORY RATING The purpose of ...

  1. Oil and power: an analysis of United States economic interests and strategies in the Middle East. Study project

    SciTech Connect (OSTI)

    Poche, C.D.

    1988-05-31

    The United States met virtually all of its oil needs from domestic sources until the early 1970s. This self-sufficiency gradually eroded as our internal production failed to keep pace with rising levels of energy consumption. As a result, our new energy needs have been satisfied primarily by petroleum imports. The 1973 Arab oil embargo and supply curtailments associated with the Iranian Revolution in 1979 were painful experiences for the nation. By 1980, the United States was importing 8.5 million barrels of oil per day at a cost many times higher than the going rate in earlier years. Dependence on Middle East oil had become a frightening reality. During the same period, trade deficits, inflation, interest rates, and balance of payment problems were increasing at an alarming rate. Since that point in time, the United States has made progress in building a strong foundation for energy security. Despite these gains the United States is rapidly approaching another critical juncture in its battle to reduce dependency on imported oil. It also suggests national economic strategies that could be employed to improve America's energy prospects for the future.

  2. Motor vehicle output and GDP, 1968-2007.

    SciTech Connect (OSTI)

    Santini, D. J.; Poyer, D. A.

    2008-01-01

    In this paper, we assess the performance of the BEA series 'value of motor vehicle output' as an indicator of the business cycle over the period 1968-2007. We statistically assess the causal relationship between real motor vehicle output (RMVO) and real gross domestic product (RGDP). This is accomplished by standard estimation and statistical methods used to assess vector autoregressive models. This assessment represents the initial results of a more encompassing research project, the intent of which is to determine the dynamic interaction of the transport sector with the overall economy. It's a start to a more comprehensive assessment of how transport and economic activity interrelate.

  3. Are You Interested in a Clean Energy Career? | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Interested in a Clean Energy Career? Are You Interested in a Clean Energy Career? September 15, 2011 - 10:08am Addthis This week, Eric talked about several ways for kids and adults to learn more about clean energy and prepare for a career in this sector. From America's Home Energy Education Challenge to the Industrial Assessment Center program, there are many ways to get excited about a career in clean energy. What do you think? Are you or your children interested in pursuing a clean energy

  4. DOE Designates Southwest Area and Mid-Atlantic Area National Interest Electric Transmission Corridors

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy (DOE) Assistant Secretary for Electricity Delivery and Energy Reliability Kevin M. Kolevar today announced the Department's designation of two National Interest Electric Transmission Corridors (National Corridors) -- the Mid-Atlantic Area National Interest Electric Transmission Corridor, and the Southwest Area National Interest Electric Transmission Corridor. These corridors include areas in two of the Nation's most populous regions with growing electricity congestion problems. The Department based its designations on data and analysis showing that persistent transmission congestion exists in these two areas.

  5. Final Report- National Database of Utility Rates and Rate Structure

    Broader source: Energy.gov [DOE]

    One of the key informational barriers for consumers, installers, regulators and policymakers, is the proper comparison cost of utility-supplied electricity that will be replaced with a Photovoltaic (PV) system. Oftentimes, these comparisons are made with national or statewide averages which results in inaccurate comparisons and conclusions. Illinois State University seeks to meet the need for accurate information about electricity costs and rate structure by building a national database of utility rates and rate structures. The database will build upon the excellent framework that was developed by the OpenEI.org initiative and extend it in several important ways. First, the data will be populated and monitored by a team of trained regulatory economists. Second, the database will be more comprehensive because it will be populated with data from newer competitive retail suppliers for states that have restructured their electricity markets to allow such suppliers. Third, the University and its Institute for Regulatory Policy Studies will maintain the database and ensure that it contains the most recent rate information.

  6. BPA Power Rates (pbl/main)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rates, please see the transmission rates web site. Inactive Rate Cases Integrated Business Review (IBR) Integrated Program Review (IPR) Quarterly Business Review (QBR) Content...

  7. Coal Transportation Rate Sensitivity Analysis

    Reports and Publications (EIA)

    2005-01-01

    On December 21, 2004, the Surface Transportation Board (STB) requested that the Energy Information Administration (EIA) analyze the impact of changes in coal transportation rates on projected levels of electric power sector energy use and emissions. Specifically, the STB requested an analysis of changes in national and regional coal consumption and emissions resulting from adjustments in railroad transportation rates for Wyoming's Powder River Basin (PRB) coal using the National Energy Modeling System (NEMS). However, because NEMS operates at a relatively aggregate regional level and does not represent the costs of transporting coal over specific rail lines, this analysis reports on the impacts of interregional changes in transportation rates from those used in the Annual Energy Outlook 2005 (AEO2005) reference case.

  8. LINEAR COUNT-RATE METER

    DOE Patents [OSTI]

    Henry, J.J.

    1961-09-01

    A linear count-rate meter is designed to provide a highly linear output while receiving counting rates from one cycle per second to 100,000 cycles per second. Input pulses enter a linear discriminator and then are fed to a trigger circuit which produces positive pulses of uniform width and amplitude. The trigger circuit is connected to a one-shot multivibrator. The multivibrator output pulses have a selected width. Feedback means are provided for preventing transistor saturation in the multivibrator which improves the rise and decay times of the output pulses. The multivibrator is connected to a diode-switched, constant current metering circuit. A selected constant current is switched to an averaging circuit for each pulse received, and for a time determined by the received pulse width. The average output meter current is proportional to the product of the counting rate, the constant current, and the multivibrator output pulse width.

  9. RECENT DEVELOPMENTS OF THE IRIS PROJECT OF INTEREST FOR LATIN AMERICA

    SciTech Connect (OSTI)

    Carelli, M.D.; Petrovic, B.

    2004-10-03

    The IRIS (International Reactor Innovative and Secure) reactor design is being developed by an international consortium of 21 organizations from ten countries, including three members from Brazil and one from Mexico. This reflects the interest that Latin America has for a project which addresses the energy needs of the region. Presented here are some of the most recent developments in the IRIS project. The project's highest priority is the current pre-application licensing with the US NRC, which has required an investigation of the major accident sequences and a preliminary probabilistic risk assessment (PRA). The results of the accident analyses confirmed the outstanding inherent safety of the IRIS configuration and the PRA analyses indicated a core damage frequency due to internal events of the order of 2E-8. This not only highlights the enhanced safety characteristic of IRIS which should enhance its public acceptance, but it has also prompted IRIS to consider the possibility of being licensed without the need for off-site emergency response planning which would have a very positive economic implication. The modular IRIS, with each module rated at {approx} 335 MWe, is of course an ideal size for developing countries as it allows to easily introduce a moderate amount of power on limited electric grids. IRIS can be deployed in single modules in regions only requiring a few hundred MWs or in multiple modules deployed successively at time intervals in large urban areas requiring a larger amount of power increasing with time. IRIS is designed to operate ''hands-off'' as much as possible, with a small crew, having in mind deployment in areas with limited infrastructure. Thus IRIS has a 48-months maintenance interval, long refueling cycles in excess of three years, and is designed to increase as much as possible operational reliability. For example, the project has recently adopted internal control rod drive mechanisms to eliminate vessel head penetrations and the

  10. CRAD, Packaging and Transfer of Hazardous Materials and Materials of National Security Interest Assessment Plan

    Broader source: Energy.gov [DOE]

    Verify that packaging and transportation safety requirements of hazardous materials and materials of national security interest have been established and are in compliance with DOE Orders 461.1 and 460.1B

  11. Licensees and economic interest in minerals after Swank and revenue ruling 83-160

    SciTech Connect (OSTI)

    McMahon, M.J. Jr.

    1983-01-01

    In the three years since the Supreme Court decided in United States v. Swank that a coal operator mining a coal deposit under a written lease terminable without cause on 30 days notice held an economic interest in the mineral in place, tax literature began noting that this decision rejected a long-held position of the Internal Revenue Service (IRS). The author assesses the impact of Revenue Ruling 83-88, in which the IRS went beyond Swank in concluding that there is no minimum period during which a lessee must have a legal right to extract minerals as a prerequisite to an economic interest. He examines the proposition that, after Swank and Revenue Ruling 83-160, licensees who previously were considered not to have acquired an economic interest, should now be found to have an economic interest in the mineral deposit they are extracting.

  12. Alliant Energy Interstate Power and Light (Gas and Electric)- Low Interest Energy Efficiency Loan Program

    Broader source: Energy.gov [DOE]

    Interstate Power and Light (Alliant Energy), in conjunction with Wells Fargo Bank, offers a low-interest loan for residential, commercial and agricultural customers who purchase and install energy...

  13. US statutes of general interest to safeguards and security officers. Revision 12/95

    SciTech Connect (OSTI)

    Cadwell, J.J.; Ruger, C.J.

    1995-12-01

    This document is one of a three volume set. This document, BNL 52202, it titled, ``US Statutes of General Interest to Safeguards and Security Officers``, and is intended for use by officers.

  14. What Kind of Green Jobs Most Interest You? | Department of Energy

    Energy Savers [EERE]

    What kind of green jobs most interest you? Each Thursday, you have the chance to share your thoughts on a question about energy efficiency or renewable energy for consumers. Please ...

  15. From: Carl Daffron To: Congestion Study Comments Subject: National Interest Energy Transmission Corridors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Carl Daffron To: Congestion Study Comments Subject: National Interest Energy Transmission Corridors Date: Monday, September 22, 2014 12:47:15 PM I am opposed to the establishment of National Interest Energy Transmission Corridors (NIETC's) for the following reasons. First, the easements place an undue burden on landowners on and near the transmission lines. The compensation cannot begin to cover the all of the losses, tangible and intangible that landowners would suffer. Second, I believe that

  16. From: Carol Johnson To: Congestion Study Comments Subject: Re: National Interest Energy Transmission Corridors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Johnson To: Congestion Study Comments Subject: Re: National Interest Energy Transmission Corridors Date: Sunday, October 19, 2014 8:20:41 AM I am opposed to the establishment of National Interest Energy Transmission Corridors (NIETC's) for the following reasons. First, the easements place an undo burden on landowners on and near the transmission lines. The compensation cannot begin to cover the all of the losses, tangible and intangible that landowners would suffer. I am a landowner in the path

  17. From: Noralie Crow To: Congestion Study Comments Subject: National Interest Energy Transmission Corridors (NIETC)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Noralie Crow To: Congestion Study Comments Subject: National Interest Energy Transmission Corridors (NIETC) Date: Monday, September 22, 2014 6:50:56 PM I am opposed to the establishment of National Interest Energy Transmission Corridors (NIETC's) for the following reasons. First, the easements place an undo burden on landowners on and near the transmission lines. The compensation cannot begin to cover the all of the losses, tangible and intangible that landowners would suffer. Second, I believe

  18. NREL Fellow Honored for 'Chemistry in the Public Interest' - News Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | NREL Fellow Honored for 'Chemistry in the Public Interest' Groundbreaking solar research garners award from American Chemical Society March 29, 2011 Dr. Arthur J. Nozik, senior research fellow at the U.S. Department of Energy's National Renewable Energy Laboratory (NREL), will be awarded the Gustavus John Esselen Award for Chemistry in the Public Interest, from the American Chemical Society's Northeastern Section at Harvard University on April 14. The Gustavus John Esselen Award for

  19. Interested Parties - Memo on Halting Title XVII Nuclear Loan Guarantees in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    MD, SC, GA, and TX | Department of Energy Interested Parties - Memo on Halting Title XVII Nuclear Loan Guarantees in MD, SC, GA, and TX Interested Parties - Memo on Halting Title XVII Nuclear Loan Guarantees in MD, SC, GA, and TX Halting_Title_XVII_Nuclear_Loan_Guarantees.pdf (67.7 KB) More Documents & Publications July 2010, Status and Outlook for Nuclear Energy In the United States Quarterly Nuclear Deployment Scorecard - October 2012 Quarterly Nuclear Deployment Scorecard - April 2014

  20. Microsoft Word - IARC_Expression of interest_Rev5_Nov2012.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Rev.01/13/2012 Fermilab Technology Applications Program Expression of Interest Project/Proposal Name: Company/Institution Street Address Phone Company URL City, State, Zip Code Fax Contact Person Name Street Address Phone Title City, State, Zip Code Email Do you wish to have information in this EOI treated as proprietary? Yes No (please circle one) Provide additional comments if desired. Comments: Is your interest in the Fermilab Technology Applications Program "general" in nature or

  1. Analysis and Selection of Analytical Tools to Assess National-Interest

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Bottlenecks Final Report | Department of Energy and Selection of Analytical Tools to Assess National-Interest Transmission Bottlenecks Final Report Analysis and Selection of Analytical Tools to Assess National-Interest Transmission Bottlenecks Final Report This work described in this report was coordinated by the Consortium for Electric Reliability Technology Solutions and funded by the U.S. Department of Energy, Office of Electric Transmission and Distribution under Contract

  2. Floating Rate Agreement | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Floating Rate Agreement Floating Rate Agreement Floating Rate Agreement (99.85 KB) More Documents & Publications Fixed Rate Agreement Energy Efficiency Loan Program Agreement Template Energy Efficiency Loan Program Agreement-Template

  3. Fast repetition rate (FRR) flasher

    DOE Patents [OSTI]

    Kolber, Zbigniew; Falkowski, Paul

    1997-02-11

    A fast repetition rate (FRR) flasher suitable for high flash photolysis including kinetic chemical and biological analysis. The flasher includes a power supply, a discharge capacitor operably connected to be charged by the power supply, and a flash lamp for producing a series of flashes in response to discharge of the discharge capacitor. A triggering circuit operably connected to the flash lamp initially ionizes the flash lamp. A current switch is operably connected between the flash lamp and the discharge capacitor. The current switch has at least one insulated gate bipolar transistor for switching current that is operable to initiate a controllable discharge of the discharge capacitor through the flash lamp. Control means connected to the current switch for controlling the rate of discharge of the discharge capacitor thereby to effectively keep the flash lamp in an ionized state between Successive discharges of the discharge capacitor. Advantageously, the control means is operable to discharge the discharge capacitor at a rate greater than 10,000 Hz and even up to a rate greater than about 250,000 Hz.

  4. Fast repetition rate (FRR) flasher

    DOE Patents [OSTI]

    Kolber, Z.; Falkowski, P.

    1997-02-11

    A fast repetition rate (FRR) flasher is described suitable for high flash photolysis including kinetic chemical and biological analysis. The flasher includes a power supply, a discharge capacitor operably connected to be charged by the power supply, and a flash lamp for producing a series of flashes in response to discharge of the discharge capacitor. A triggering circuit operably connected to the flash lamp initially ionizes the flash lamp. A current switch is operably connected between the flash lamp and the discharge capacitor. The current switch has at least one insulated gate bipolar transistor for switching current that is operable to initiate a controllable discharge of the discharge capacitor through the flash lamp. Control means connected to the current switch for controlling the rate of discharge of the discharge capacitor thereby to effectively keep the flash lamp in an ionized state between successive discharges of the discharge capacitor. Advantageously, the control means is operable to discharge the discharge capacitor at a rate greater than 10,000 Hz and even up to a rate greater than about 250,000 Hz. 14 figs.

  5. Variable gas leak rate valve

    DOE Patents [OSTI]

    Eernisse, Errol P.; Peterson, Gary D.

    1976-01-01

    A variable gas leak rate valve which utilizes a poled piezoelectric element to control opening and closing of the valve. The gas flow may be around a cylindrical rod with a tubular piezoelectric member encircling the rod for seating thereagainst to block passage of gas and for reopening thereof upon application of suitable electrical fields.

  6. Evaluation Ratings Definitions (Excluding Utilization of Small...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    (Excluding Utilization of Small Business) Rating Definition Note Exceptional ... Definitions (Utilization of Small Business) Rating Definition Note Exceptional ...

  7. Economic Effects of High Oil Prices (released in AEO2006)

    Reports and Publications (EIA)

    2006-01-01

    The Annual Energy Outlook 2006 projections of future energy market conditions reflect the effects of oil prices on the macroeconomic variables that affect oil demand, in particular, and energy demand in general. The variables include real gross domestic product (GDP) growth, inflation, employment, exports and imports, and interest rates.

  8. 1993 Wholesale Power and Transmission Rate Schedules.

    SciTech Connect (OSTI)

    US Bonneville Power Administration

    1993-10-01

    Bonneville Power Administration 1993 Wholesale Power Rate Schedules and General Rate Schedule Provisions and 1993 Transmission Rate Schedules and General Transmission Rate Schedule Provisions, contained herein, were approved on an interim basis effective October 1, 1993. These rate schedules and provisions were approved by the Federal Energy Commission, United States Department of Energy, in September, 1993. These rate schedules and provisions supersede the Administration`s Wholesale Power Rate Schedules and General Rate Schedule Provisions and Transmission Rate Schedules and General Transmission Rate Schedule Provisions effective October 1, 1991.

  9. Special Report on "Allegations of Conflict of Interest Regarding Licensing of PROTECT by Argonne National Laboratory"

    SciTech Connect (OSTI)

    2009-08-01

    In February 2009, the Office of Inspector General received a letter from Congressman Mark Steven Kirk of Illinois, which included constituent allegations that an exclusive technology licensing agreement by Argonne National Laboratory was tainted by inadequate competition, conflicts of interest, and other improprieties. The technology in question was for the Program for Response Options and Technology Enhancements for Chemical/Biological Terrorism, commonly referred to as PROTECT. Because of the importance of the Department of Energy's technology transfer program, especially as implementation of the American Recovery and Reinvestment Act matures, we reviewed selected aspects of the licensing process for PROTECT to determine whether the allegations had merit. In summary, under the facts developed during our review, it was understandable that interested parties concluded that there was a conflict of interest in this matter and that Argonne may have provided the successful licensee with an unfair advantage. In part, this was consistent with aspects of the complaint from Congressman Kirk's constituent.

  10. Public goods and private interests: Understanding non-residential demand for green power

    SciTech Connect (OSTI)

    Wiser, Ryan H.; Fowlie, Meredith; Holt, Edward A.

    2001-01-01

    This article presents the results of the first large-scale mail survey of non-residential green power customers in the United States. The survey explored the motivations, attitudes, and experiences of 464 business, non-profit, and public-sector customers that have voluntarily opted to purchase - and frequently pay a premium for - renewable electricity. Results of this study should be of value to marketers interested in targeting these customer segments, to policy makers interested in fostering and understanding non-residential demand for green power, and to academics pondering the motivations for firms to engage in such voluntary environmental initiatives.

  11. Fact #740: August 13, 2012 Interest in Smaller Vehicles is on the Rise |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy 0: August 13, 2012 Interest in Smaller Vehicles is on the Rise Fact #740: August 13, 2012 Interest in Smaller Vehicles is on the Rise Consumer Reports conducted a survey of 1,702 adults in April 2012. Respondents were asked what type of vehicle they currently own and what type of vehicle they plan to buy next. The responses reveal a shift from larger vehicle types including large sedans, minivans and large SUVs, toward smaller cars and SUVs. Of those surveyed, 17% owned

  12. Interested in Hydrogen and Fuel Cell Technologies? Help Shape the H2 Refuel

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    H-Prize Competition | Department of Energy Interested in Hydrogen and Fuel Cell Technologies? Help Shape the H2 Refuel H-Prize Competition Interested in Hydrogen and Fuel Cell Technologies? Help Shape the H2 Refuel H-Prize Competition March 27, 2014 - 1:52pm Addthis The Energy Department recently released a new video in its popular Energy 101 series showing how fuel cell technology generates clean electricity from hydrogen to power our buildings and transportation-while emitting nothing but

  13. Transit Timing Observations from Kepler: VII. Potentially interesting candidate systems from Fourier-based statistical tests

    SciTech Connect (OSTI)

    Steffen, Jason H.; Ford, Eric B.; Rowe, Jason F.; Fabrycky, Daniel C.; Holman, Matthew J.; Welsh, William F.; Borucki, William J.; Batalha, Natalie M.; Bryson, Steve; Caldwell, Douglas A.; Ciardi, David R.; /Caltech /NASA, Ames /SETI Inst., Mtn. View

    2012-01-01

    We analyze the deviations of transit times from a linear ephemeris for the Kepler Objects of Interest (KOI) through Quarter six (Q6) of science data. We conduct two statistical tests for all KOIs and a related statistical test for all pairs of KOIs in multi-transiting systems. These tests identify several systems which show potentially interesting transit timing variations (TTVs). Strong TTV systems have been valuable for the confirmation of planets and their mass measurements. Many of the systems identified in this study should prove fruitful for detailed TTV studies.

  14. What Is the Right Rate? Loan Rates and Demand | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Is the Right Rate? Loan Rates and Demand What Is the Right Rate? Loan Rates and Demand Better Buildings Neighborhood Program Financing Peer Exchange Call: "What is the Right Rate?" ...

  15. Department of Energy Announces Plans for Additional Comment Period on National Interest Electric Transmission Corridors

    Broader source: Energy.gov [DOE]

    The Department has decided that, prior to issuing a report that designates any national interest electric transmission corridor, the Department will first issue any designation that it is considering in draft form, so as to allow additional opportunities for review and comment by affected States, regional entities, and the general public.

  16. Report to Congress: Expressions of interest in commercial clean coal technology projects in foreign countries

    SciTech Connect (OSTI)

    1995-06-01

    This report was prepared in response to the guidance provided by the Congress in the course of the Fiscal Year 1995 appropriations process for the Department of Energy`s (DOE) Office of Fossil Energy (FE). As described in detail below, DOE was directed to make the international dissemination of Clean Coal Technologies (CCTs) an integral part of its policy to reduce greenhouse gas emissions in developing countries. Congress directed DOE to solicit ``Statements of Interest`` in commercial projects employing CCTs in countries projected to have significant growth in greenhouse gas emissions. Additionally, DOE was asked to submit to the Congress a report that analyzes the information contained in the Statements of Interest, and that identifies the extent to which various types of Federal incentives would accelerate the commercial availability of these technologies in an international context. In response to DOE`s solicitation of 18 November 1994, 77 Statements of Interest were received from 33 companies, as well as five additional materials. The contents of these submittals, including the requested Federal incentives, the CCTs proposed, the possible host countries, and the environmental aspects of the Statements of Interest, are described and analyzed in the chapters that follow.

  17. Packaging and Transfer or Transportation of Materials of National Security Interest

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-04-26

    To establish requirements and responsibilities for offsite shipments of naval nuclear fuel elements, Category I and Category II special nuclear material, nuclear explosives, nuclear components, special assemblies, and other materials of national security interest. Cancels DOE O 461.1. Canceled by DOE O 461.1B and DOE O 461.2.

  18. Packaging and Transportation for Offsite Shipment of Materials of National Security Interest

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2016-07-20

    The purpose of this Order is to make clear that the packaging and transportation of all offsite shipments of Materials of National Security Interest (MNSI) for DOE must be conducted in accordance with Department of Transportation (DOT) and Nuclear Regulatory Commission (NRC) regulations that would be applicable to comparable commercial shipments, except where an alternative course of action is identified in this Order.

  19. An update on environmental, health and safety issues of interest to the photovoltaic industry

    SciTech Connect (OSTI)

    Moskowitz, P.D.; Viren, J.; Fthenakis, V.M.

    1992-08-01

    There is growing interest in the environmental, health, and safety issues related to new photovoltaic technologies as they approach commercialization. Such issues include potential toxicity of II--VI compounds; the impacts of new environmental regulations on module manufacturers; and, the need for recycling of spent modules and manufacturing wastes. This paper will review these topics. 20 refs.

  20. Packaging and Transfer or Transportation of Materials of National Security Interest

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2000-09-29

    To establish requirements and responsibilities for the Transportation Safeguards System (TSS) packaging and transportation and onsite transfer of nuclear explosives, nuclear components, Naval nuclear fuel elements, Category I and Category II special nuclear materials, special assemblies, and other materials of national security interest. Cancels: DOE 5610.12 and DOE 5610.14.

  1. Wholesale Power Rate Schedules | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Power Rate Schedules October 1, 2011 CBR-1-H Wholesale Power Rate Schedule Area: Big Rivers and Henderson, KY System: CU October 1, 2011 CM-1-H Wholesale Power Rate...

  2. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: electric load data Type Term Title Author Replies Last Post sort icon...

  3. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: DOE Type Term Title Author Replies Last Post sort icon Blog entry DOE...

  4. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: API Type Term Title Author Replies Last Post sort icon Blog entry API...

  5. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: EZFeed Type Term Title Author Replies Last Post sort icon Blog entry...

  6. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: Database Type Term Title Author Replies Last Post sort icon Blog entry...

  7. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: bug Type Term Title Author Replies Last Post sort icon Discussion bug...

  8. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: energy efficiency Type Term Title Author Replies Last Post sort icon...

  9. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: clean energy Type Term Title Author Replies Last Post sort icon Blog...

  10. Utility Rate | OpenEI Community

    Open Energy Info (EERE)

    Rate Home > Utility Rate > Posts by term > Utility Rate Content Group Activity By term Q & A Feeds Term: datasets Type Term Title Author Replies Last Post sort icon Blog entry...