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  1. UNEDITED PREPUBLICATION COPY: FINAL WORDING SUBJECT TO CHANGE i BURNING PLASMA

    E-Print Network [OSTI]

    and Astronomy Division on Engineering and Physical Sciences #12;UNEDITED PREPUBLICATION COPY: FINAL WORDING Academy of Engineering, and the Institute of Medicine. The members of the committee responsible and engineering research, dedicated to the furtherance of science and technology and to their use for the general

  2. High Resolution Genome Wide Binding Event Finding and Motif Discovery Reveals Transcription Factor Spatial Binding Constraints

    E-Print Network [OSTI]

    Guo, Yuchun

    An essential component of genome function is the syntax of genomic regulatory elements that determine how diverse transcription factors interact to orchestrate a program of regulatory control. A precise characterization ...

  3. Finding

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouthReport for the t-) S/,,5 'a C O M P R E H E N S I551 - g--Finding

  4. Mechanism of Transcriptional Bursting in Bacteria

    E-Print Network [OSTI]

    Li, Tiejun

    Mechanism of Transcriptional Bursting in Bacteria Shasha Chong,1,5 Chongyi Chen,1,2,5 Hao Ge,3 phenomenon has not been understood. Here, we present the mechanism in bacteria. We developed a high. Together, these findings prove that transcriptional bursting of highly ex- pressed genes in bacteria

  5. The Transcription Factor Encyclopedia

    E-Print Network [OSTI]

    2012-01-01

    Transcription Factor Encyclopedia. Genome Biology 2012 13:Factor Encyclopedia. Gen- ome Biology 2012, 13:000. where ‘Biology 2012, 13:R24 http://genomebiology.com/2012/13/3/R24 SOFTWARE Open Access The Transcription Factor Encyclopedia

  6. Transcription Pharmaceutical Company

    E-Print Network [OSTI]

    Oliva, Aude

    Transcription Pharmacy CDC Pharmaceutical Company Pharmacy Benefits Manager Analytics ICU thedatamap.org #12;Transcription Pharmacy CDC Pharmaceutical Company Pharmacy Benefits Manager Analytics Management Researcher Consulting Physician Health IT Other Government Federal Trade Commission You

  7. Find Clear

    Broader source: Energy.gov (indexed) [DOE]

    p align"left">

    Find Clear Slide Title Duration Status myMail@adobe.com http:Adobe.com More Info>>

  8. Find Books

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives & Financing »FindBooks

  9. Find Preprints

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives & Financing|Preprints Find

  10. Find Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &Reports Find Reports Most

  11. Find Standards

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &Reports Find Reports

  12. Searching for the nik Operon: How a Ligand-Responsive Transcription Factor Hunts for Its DNA Binding Site

    E-Print Network [OSTI]

    Phillips, Christine M.

    Transcription factors regulate a wide variety of genes in the cell and play a crucial role in maintaining cellular homeostasis. A major unresolved issue is how transcription factors find their specific DNA binding sequence ...

  13. Microsoft Word - Transcript_120508.doc

    Office of Environmental Management (EM)

    Seward Carol Battershell Daniel Cohen Matthew McMillen Advanced Technology Vehicles Manufacturing Loan Program Transcript from December 5, 2008 Public Meeting 2 TABLE OF CONTENTS...

  14. Transcript from 12/05/08 | Department of Energy

    Energy Savers [EERE]

    from 120508 More Documents & Publications Transcript from 120108 Manufacturing Pre-Solicitation Transcript SERC Photovoltaics for Residential Buildings Webinar Transcript...

  15. Discovering Regulatory Overlapping RNA Transcripts

    E-Print Network [OSTI]

    Danford, Timothy William

    STEREO is a novel algorithm that discovers cis-regulatory RNA interactions by assembling complete and potentially overlapping same-strand RNA transcripts from tiling expression data. STEREO first identifies coherent segments ...

  16. EIS-0458: Scoping Meeting Transcript

    Broader source: Energy.gov [DOE]

    Transcript of the public scoping meeting on the draft EIS for the proposed loan guarantee for the First Solar Topaz Solar Farm Project in San Luis Obispo County, CA.

  17. Analysis of transcriptional regulatory circuitry

    E-Print Network [OSTI]

    Rinaldi, Nicola J., 1974-

    2004-01-01

    The research in this thesis has focused on the analysis of data from two types of microarray technologies with the goal of improving understanding of transcriptional regulatory circuitry in yeast. These microarray technologies, ...

  18. Transcript for Building America Video

    Broader source: Energy.gov [DOE]

    Transcript of a video about how DOE’s Building America program is helping to bridge the gap between homes with high energy costs and homes that are healthy, durable, and energy efficient.

  19. Breast Cancer Research Finding Answers. Finding Cures.

    E-Print Network [OSTI]

    Kowalczykowski, Stephen C.

    Breast Cancer Research Finding Answers. Finding Cures. Thanks to improvements in treatment and early detection, more and more women are surviving breast cancer. In fact, the five-year survival rate for women with breast cancer today is 90%, up from only 63% in the 1960s. While progress has clearly been

  20. Nucleosome-mediated cooperativity between transcription factors

    E-Print Network [OSTI]

    Leonid A. Mirny

    2009-01-19

    Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes. The classical model of cooperativity requires direct interactions between TFs, thus constraining the arrangement of TFs sites in a CRR. On the contrary, genomic and functional studies demonstrate a great deal of flexibility in such arrangements with variable distances, numbers of sites, and identities of the involved TFs. Such flexibility is inconsistent with the cooperativity by direct interactions between TFs. Here we demonstrate that strong cooperativity among non-interacting TFs can be achieved by their competition with nucleosomes. We find that the mechanism of nucleosome-mediated cooperativity is mathematically identical to the Monod-Wyman-Changeux (MWC) model of cooperativity in hemoglobin. This surprising parallel provides deep insights, with parallels between heterotropic regulation of hemoglobin (e.g. Bohr effect) and roles of nucleosome-positioning sequences and chromatin modifications in gene regulation. Characterized mechanism is consistent with numerous experimental results, allows substantial flexibility in and modularity of CRRs, and provides a rationale for a broad range of genomic and evolutionary observations. Striking parallels between cooperativity in hemoglobin and in transcription regulation point at a new design principle that may be used in range of biological systems.

  1. Financing Residential Energy Efficiency with Carbon Offsets Transcript...

    Energy Savers [EERE]

    Financing Residential Energy Efficiency with Carbon Offsets Transcript Financing Residential Energy Efficiency with Carbon Offsets Transcript This document contains the transcript...

  2. Public Meeting Transcript: Sustainable Design Standards for Federal...

    Energy Savers [EERE]

    Public Meeting Transcript: Sustainable Design Standards for Federal Buildings Public Meeting Transcript: Sustainable Design Standards for Federal Buildings This transcript is from...

  3. Connections between Alternative Transcription and Alternative Splicing in Mammals

    E-Print Network [OSTI]

    Spiridonov, Alexey Nikolaevich

    The majority of mammalian genes produce multiple transcripts resulting from alternative splicing (AS) and/or alternative transcription initiation (ATI) and alternative transcription termination (ATT). Comparative analysis ...

  4. Highly efficient Cas9-mediated transcriptional programming

    E-Print Network [OSTI]

    Chavez, Alejandro

    The RNA-guided nuclease Cas9 can be reengineered as a programmable transcription factor. However, modest levels of gene activation have limited potential applications. We describe an improved transcriptional regulator ...

  5. OFFICIAL TRANSCRIPT REQUEST FORM Biomedical Sciences

    E-Print Network [OSTI]

    Cook, Greg

    OFFICIAL TRANSCRIPT REQUEST FORM Biomedical Sciences Bowman Gray Campus This form, Biomedical Sciences. There is no charge for transcripts; however, the requestor must pay any special fees Graduate School of Arts and Sciences Biomedical Sciences, Bowman Gray Campus Medical Center

  6. Residential Retrofit Program Design Guide Overview Transcript...

    Energy Savers [EERE]

    Overview Sustainable Energy Resources for Consumers Webinar on Residential Geothermal Heat Pump Retrofit Transcript Weatherization & Intergovernmental Programs Office Home...

  7. The Prosodic Transcription of a Corpus of Hong Kong English: Collection Criteria, Transcription System and Preliminary Findings

    E-Print Network [OSTI]

    . The intonation system proposed by David Brazil (1997) known as the Brazil System is being used for the prosodic intonation along with discourse features. Below are the labels adopted from the Brazil System of intonation/termina-tion respectively Tone unit boundaries: // Prominence refers to the stressed syllables. Tone is the tonic or nucleus

  8. TO APPEAR IN: Z MAGAZINE, JUNE 2006. (UNEDITED VERSION)

    E-Print Network [OSTI]

    O'Donnell, Tom

    sufficient low-level enriched uranium to use in fuel rods for their Russian-built nuclear power plant. But to Al Qaeda," so too, the true reason for the present U.S.-Iran crisis is not the ostensible "nuclear threat" posed by Iran. Rather, the American push against Iran's nuclear program and for "regime change

  9. UNEDITED PREPRINT Building a dynamic growth model for trembling

    E-Print Network [OSTI]

    García, Oscar

    ´ia.1 University of Northern British Columbia, 3333 University Way, Prince George, BC, Canada V2N 4Z9. 1

  10. University of Connecticut, Office of the Registrar, Transcript Request Form Transcript Request Form -University of Connecticut

    E-Print Network [OSTI]

    Alpay, S. Pamir

    University of Connecticut, Office of the Registrar, Transcript Request Form Transcript Request Form - University of Connecticut Office of the Registrar, Unit 4077T, Storrs, CT 06269-4077T Forms of Connecticut under other names, please indicate them here

  11. How do I get my training transcripts? 1. HR Training Transcript

    E-Print Network [OSTI]

    Howitt, Ivan

    How do I get my training transcripts? 1. HR Training Transcript There are two ways to access your HR Training Transcript ­ either through Banner Self Service or 49er Express. I) Using Banner Self credentials, then select the "Employee" tab Select the "Human Resources Training Courses Completed" link II

  12. UNIVERSITY OF NEW HAMPSHIRE TRANSCRIPT REQUEST

    E-Print Network [OSTI]

    UNIVERSITY OF NEW HAMPSHIRE TRANSCRIPT REQUEST NOTE: A transcript is a complete history of all your being mailed to the wrong address(es). Rev. 11/2013 STUDENT ID# (or last 4 of SSN) University of New Hampshire Office of Registrar Stoke Hall 11 Garrison Avenue Durham, NH 03824-3511 603-862-1587 phone 603

  13. OFFICIAL TRANSCRIPT REQUEST FORM Biomedical Sciences

    E-Print Network [OSTI]

    Cook, Greg

    OFFICIAL TRANSCRIPT REQUEST FORM Biomedical Sciences Bowman Gray Campus This form is to be used by current students and alumni of the WFU Graduate School of Arts and Sciences, Biomedical Sciences this form to: ATTN: Transcripts Wake Forest University Graduate School of Arts and Sciences Biomedical

  14. Evolution of transcription networks in response to temporal fluctuations

    E-Print Network [OSTI]

    Hespanha, João Pedro

    Evolution of transcription networks in response to temporal fluctuations Journal: Evolution, Evolution & Marine Biology Keywords: Population Genetics, Epistasis, Genetic Networks, Transcription Evolution: For Review Only #12;EVOLUTION OF TRANSCRIPTION NETWORKS IN RESPONSE TO TEMPORAL FLUCTUATIONS

  15. Find Articles/Databases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives & Financing »Find

  16. Find Theses and Dissertations

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &Reports Find

  17. Find eBooks

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &ReportseBooks Find eBooks

  18. EIS-0465: Scoping Meeting Transcript, 3/24/2011 | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Scoping Meeting Transcript, 3232011 EIS-0465: Scoping Meeting Transcript, 3222011 QER Public Meeting in Portland, OR: Electricity Transmission, Storage and Distribution - West...

  19. Blackout 2003: Transcript of Technical Conference with the Electric...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transcript of Technical Conference with the Electric System Investigation Team Blackout 2003: Transcript of Technical Conference with the Electric System Investigation Team...

  20. Transcriptional profiling of fetal hypothalamic TRH neurons

    E-Print Network [OSTI]

    Guerra-Crespo, Magdalena; Perez-Monter, Carlos; Janga, Sarath Chandra; Castillo-Ramirez, Santiago; Gutierrez-Rios, Rosa M.; Joseph-Bravo, Patricia; Perez-Martinez, Leonor; Charli, Jean-Louis

    2011-05-10

    in the GFP+ cells, we identified three transcription factors whose expression has not been previously reported within the hypothala- mus in vivo. These transcripts include the zinc finger domain-containing transcription factor Klf4 [29-32], the TGFb... °C (Klf4) for 1 min, a polymerization step at 72°C for 1 min and a final extension at 72°C for 10 min. PCR pro- ducts were electrophoresed in 2% agarose gel and bands stained with ethidium bromide. Acknowledgements We thank Affymetrix...

  1. Phonetic transcription standards for european names (onomastica). 

    E-Print Network [OSTI]

    Schmidt, Mark; Fitt, Susan; Scott, Christina; Jack, Mervyn A

    1993-01-01

    This paper details the standards identified for phonetic transcription of names as part of the ONOMASTICA project, a European-wide research initiative for the construction of a multi-language pronunciation lexicon ...

  2. Oracle Analysis of Sparse Automatic Music Transcription

    E-Print Network [OSTI]

    Plumbley, Mark

    Oracle Analysis of Sparse Automatic Music Transcription Ken O'Hanlon , Hidehisa Nagano , and Mark {keno,nagano,Mark.Plumbley}@eecs.qmul.ac.uk Abstract. We have previously proposed a structured sparse

  3. Transcription factor-based biosensors for detecting dicarboxylic acids

    SciTech Connect (OSTI)

    Dietrich, Jeffrey; Keasling, Jay

    2014-02-18

    The invention provides methods and compositions for detecting dicarboxylic acids using a transcription factor biosensor.

  4. Domain Assignment to Transcription FactorsDomain Assignment to Transcription Factors 412 Proteins with

    E-Print Network [OSTI]

    Babu, M. Madan

    Domain Assignment to Transcription FactorsDomain Assignment to Transcription Factors 412 Proteins with at least one SCOP DBD assignment 412 Proteins with at least one SCOP DBD assignment 7 proteins with PFAM DBD assignment 7 proteins with PFAM DBD assignment 419 proteins with DBD assignment419 proteins

  5. Facilitated diffusion framework for transcription factor search with conformational changes

    E-Print Network [OSTI]

    Jérôme Cartailler; Jürgen Reingruber

    2015-07-09

    Cellular responses often require the fast activation or repression of specific genes, which depends on Transcription Factors (TFs) that have to quickly find the promoters of these genes within a large genome. Transcription Factors (TFs) search for their DNA promoter target by alternating between bulk diffusion and sliding along the DNA, a mechanism known as facilitated diffusion. We study a facilitated diffusion framework with switching between three search modes: a bulk mode and two sliding modes triggered by conformational changes between two protein conformations. In one conformation (search mode) the TF interacts unspecifically with the DNA backbone resulting in fast sliding. In the other conformation (recognition mode) it interacts specifically and strongly with DNA base pairs leading to slow displacement. From the bulk, a TF associates with the DNA at a random position that is correlated with the previous dissociation point, which implicitly is a function of the DNA structure. The target affinity depends on the conformation. We derive exact expressions for the mean first passage time (MFPT) to bind to the promoter and the conditional probability to bind before detaching when arriving at the promoter site. We systematically explore the parameter space and compare various search scenarios. We compare our results with experimental data for the dimeric Lac repressor search in E.Coli bacteria. We find that a coiled DNA conformation is absolutely necessary for a fast MFPT. With frequent spontaneous conformational changes, a fast search time is achieved even when a TF becomes immobilized in the recognition state due to the specific bindings. We find a MFPT compatible with experimental data in presence of a specific TF-DNA interaction energy that has a Gaussian distribution with a large variance.

  6. Method to determine transcriptional regulation pathways in organisms

    DOE Patents [OSTI]

    Gardner, Timothy S.; Collins, James J.; Hayete, Boris; Faith, Jeremiah

    2012-11-06

    The invention relates to computer-implemented methods and systems for identifying regulatory relationships between expressed regulating polypeptides and targets of the regulatory activities of such regulating polypeptides. More specifically, the invention provides a new method for identifying regulatory dependencies between biochemical species in a cell. In particular embodiments, provided are computer-implemented methods for identifying a regulatory interaction between a transcription factor and a gene target of the transcription factor, or between a transcription factor and a set of gene targets of the transcription factor. Further provided are genome-scale methods for predicting regulatory interactions between a set of transcription factors and a corresponding set of transcriptional target substrates thereof.

  7. Weintraub Meeting 1998 Transcription, Chromatin, & Development

    E-Print Network [OSTI]

    Bass, Brenda L.

    Molecular Study of Neurons and Pancreatic Beta Cells" 3:30 - 5:00 Keith Blackwell, Harvard University "Regulation of Transcription by SKN-1 and PIE-1 Proteins" 5:00 - 6:30 Raphael Kopan, Washington University Bass, University of Utah "Does Your RNA Contain Inosine?" 3:30 - 5:00 Matthew Thayer, Vullum Insitute

  8. Multiple roles for the zebrafish transcriptional activator SBF/Staf 

    E-Print Network [OSTI]

    Halbig, Kari Michele

    2009-05-15

    Eukaryotic transcriptional activators stimulate transcription of genes otherwise expressed at low levels. The typical activator operates by binding to specific sites on DNA with its activating region contacting the ...

  9. Finding a Job in Mathematics

    E-Print Network [OSTI]

    Below we have attempted to collect a number of links to information on finding jobs ... (Purdue); The National Security Agency is reputed to be the world's largest ...

  10. Transcription factor search for a DNA promoter in a three-states model

    E-Print Network [OSTI]

    Juergen Reingruber; David Holcman

    2011-04-12

    To ensure fast gene activation, Transcription Factors (TF) use a mechanism known as facilitated diffusion to find their DNA promoter site. Here we analyze such a process where a TF alternates between 3D and 1D diffusion. In the latter (TF bound to the DNA), the TF further switches between a fast translocation state dominated by interaction with the DNA backbone, and a slow examination state where interaction with DNA base pairs is predominant. We derive a new formula for the mean search time, and show that it is faster and less sensitive to the binding energy fluctuations compared to the case of a single sliding state. We find that for an optimal search, the time spent bound to the DNA is larger compared to the 3D time in the nucleus, in agreement with recent experimental data. Our results further suggest that modifying switching via phosphorylation or methylation of the TF or the DNA can efficiently regulate transcription.

  11. mRNA Destabilization: The Role of the 3?UTR in Post-transcriptional Regulation of Wnt8 Transcripts 

    E-Print Network [OSTI]

    Butler, Annika D 1987-

    2012-07-11

    for the designation as UNDERGRADUATE RESEARCH SCHOLAR A Senior Scholars Thesis by ANNIKA DAWN BUTLER mRNA DESTABILIZATION: THE ROLE OF THE 3’ UTR IN POST- TRANSCRIPTIONAL REGULATION OF WNT8 TRANSCRIPTS Approved by: Research Advisor: Arne C... as UNDERGRADUATE RESEARCH SCHOLAR A Senior Scholars Thesis by ANNIKA DAWN BUTLER iii ABSTRACT mRNA Destabilization: The Role of the 3’UTR in Post-transcriptional Regulation of Wnt8 Transcripts. (April 2010) Annika Dawn Butler Department of Biology...

  12. Diffusion, dimensionality and noise in transcriptional regulation

    E-Print Network [OSTI]

    Gasper Tkacik; William Bialek

    2007-12-12

    The precision of biochemical signaling is limited by randomness in the diffusive arrival of molecules at their targets. For proteins binding to the specific sites on the DNA and regulating transcription, the ability of the proteins to diffuse in one dimension by sliding along the length of the DNA, in addition to their diffusion in bulk solution, would seem to generate a larger target for DNA binding, consequently reducing the noise in the occupancy of the regulatory site. Here we show that this effect is largely cancelled by the enhanced temporal correlations in one dimensional diffusion. With realistic parameters, sliding along DNA has surprisingly little effect on the physical limits to the precision of transcriptional regulation.

  13. HIV transcription is induced in dying cells

    SciTech Connect (OSTI)

    Woloschak, G.E.; Chang-Liu, Chin-Mei; Schreck, S. |; Panozzo, J.; Libertin, C.R.

    1996-02-01

    Using HeLa cells stably transfected with an HIV-LTR-CAT construct, we demonstrated a peak in CAT induction that occurs in viable (but not necessarily cell-division-competent) cells 24 h following exposure to some cell-killing agents. {gamma} rays were the only cell-killing agent which did not induce HIV transcription; this can be attributed to the fact that {gamma}-ray-induced apoptotic death requires functional p53, which is not present in HeLa cells. For all other agents, HIV-LTR induction was dose-dependent and correlated with the amount of cell killing that occurred in the culture. Doses which caused over 99% cell killing induced HIV-LTR transcription maximally, demonstrating that cells that will go on to die by 14 days are the cells expressing HIV-LTR-CAT.

  14. FINDING BALANCE: ENHANCING PHYSICAL, EMOTIONAL,

    E-Print Network [OSTI]

    FINDING BALANCE: ENHANCING PHYSICAL, EMOTIONAL, AND SOCIAL WELL-BEING 3rd Annual Conference for psychologists requesting CE credits TOPICS INCLUDE: How finding "balance" can support our physical, emotional, and social well-being Balance exercises and physical fitness to prevent injuries and cognitive decline

  15. Involvement of tristetraprolin in transcriptional activation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin

    SciTech Connect (OSTI)

    Ness, Gene C., E-mail: gness@hsc.usf.edu [Department of Molecular Medicine, College of Medicine, University of South Florida, Tampa, FL 33612 (United States); Edelman, Jeffrey L.; Brooks, Patricia A. [Department of Molecular Medicine, College of Medicine, University of South Florida, Tampa, FL 33612 (United States)] [Department of Molecular Medicine, College of Medicine, University of South Florida, Tampa, FL 33612 (United States)

    2012-03-30

    Highlights: Black-Right-Pointing-Pointer siRNAs to tristetraprolin blocks transcription of HMGR in vivo in rat liver. Black-Right-Pointing-Pointer siRNAs to tristetraprolin inhibits insulin activation of HMGR transcription. Black-Right-Pointing-Pointer Insulin acts to rapidly increase tristetraprolin in liver nuclear extracts. -- Abstract: Several AU-rich RNA binding element (ARE) proteins were investigated for their possible effects on transcription of hepatic 3-hydroxy-3-methyglutaryl coenzyme A reductase (HMGR) in normal rats. Using in vivo electroporation, four different siRNAs to each ARE protein were introduced together with HMGR promoter (-325 to +20) luciferase construct and compared to saline controls. All four siRNAs to tristetraprolin (TTP) completely eliminated transcription from the HMGR promoter construct. Since insulin acts to rapidly increase hepatic HMGR transcription, the effect of TTP siRNA on induction by insulin was tested. The 3-fold stimulation by insulin was eliminated by this treatment. In comparison, siRNA to AU RNA binding protein/enoyl coenzyme A hydratase (AUH) had no effect. These findings indicate a role for TTP in the insulin-mediated activation of hepatic HMGR transcription.

  16. Analysis of transcriptional responses in the mouse dorsal striatum following acute MDMA (Ecstasy): identification of ERK-controlled genes.

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ): identification of ERK-controlled genes. J. Salzmann, C. Canestrelli, F. Noble*, and C. Marie-Claire. Université rewarding effects in mice were dependent upon ERK activation and that dorsal striatum was a critical region for mediating ERK-dependent Egr1 MDMA-induced transcription. Here, we extend these findings by showing that MDMA

  17. Find a Job | Careers | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you not find whatGasEnergyfeature photoTheory ChalkboardFiberFindFind a

  18. RESEARCH GIVES EDGE TO FINDING

    E-Print Network [OSTI]

    Angenent, Lars T.

    home revisited. COVER STORY Séamus Davis and the path to faculty renewal BY BILL STEELE A look at whatSÉAMUS DAVIS AND HIS FANTASTIC MACHINE RESEARCH GIVES EDGE TO FINDING NEXT GENERATION OF FACULTY 14

  19. Peak finding using biorthogonal wavelets

    SciTech Connect (OSTI)

    Tan, C.Y.

    2000-02-01

    The authors show in this paper how they can find the peaks in the input data if the underlying signal is a sum of Lorentzians. In order to project the data into a space of Lorentzian like functions, they show explicitly the construction of scaling functions which look like Lorentzians. From this construction, they can calculate the biorthogonal filter coefficients for both the analysis and synthesis functions. They then compare their biorthogonal wavelets to the FBI (Federal Bureau of Investigations) wavelets when used for peak finding in noisy data. They will show that in this instance, their filters perform much better than the FBI wavelets.

  20. Writing audit findings: Be reasonable!

    SciTech Connect (OSTI)

    Girvin, N.W.

    1992-05-01

    A customary approach to auditing and reporting deficiencies is to keep a running list of those that are found, evaluate the severity of each, and based on the evidence, document findings or observations or concerns in an audit report. The report is issued and the auditee is normally requested to address ``root cause`` as part of their corrective action. This paper describes a ``root problems`` approach to documenting audit findings that is designed not only to put the QA auditor in a more favorable light, but to more effectively enable the auditee to identify root cause and meaningful corrective action. The positive results of this approach are considerable. You will have fewer findings but those you do have will be substantial. You will cite requirements that sound reasonable and make arguments difficult. If some of the supporting deficiencies (examples) prove to be incorrect, you will still have ample support for the original finding. You will be seen as reasonable individual who can help lead the auditee towards identification of root cause without taking away part of the responsibility. You even have a fair chance of fostering a sense of commitment to quality improvement on the auditee`s part. This in itself, is its own reward.

  1. Writing audit findings: Be reasonable

    SciTech Connect (OSTI)

    Girvin, N.W.

    1992-05-01

    A customary approach to auditing and reporting deficiencies is to keep a running list of those that are found, evaluate the severity of each, and based on the evidence, document findings or observations or concerns in an audit report. The report is issued and the auditee is normally requested to address root cause'' as part of their corrective action. This paper describes a root problems'' approach to documenting audit findings that is designed not only to put the QA auditor in a more favorable light, but to more effectively enable the auditee to identify root cause and meaningful corrective action. The positive results of this approach are considerable. You will have fewer findings but those you do have will be substantial. You will cite requirements that sound reasonable and make arguments difficult. If some of the supporting deficiencies (examples) prove to be incorrect, you will still have ample support for the original finding. You will be seen as reasonable individual who can help lead the auditee towards identification of root cause without taking away part of the responsibility. You even have a fair chance of fostering a sense of commitment to quality improvement on the auditee's part. This in itself, is its own reward.

  2. Finding CDs with Library Search

    E-Print Network [OSTI]

    Chrispell, John

    from the menu, enter your search terms, and click the green magnifying glass to search. Click details your search terms, limit to Sound Recordings, then click Search. Click the title to see what the tracksFinding CDs with Library Search BEGIN YOUR SEARCH AT http://library.tulane.edu Select Audio & Video

  3. TAP Webcast Transcript July-29, 2009 | Department of Energy

    Energy Savers [EERE]

    Documents & Publications How to Estimate the Economic Impacts from Renewable Energy SERC Photovoltaics for Residential Buildings Webinar Transcript Sustainable Energy Resources...

  4. Blackout 2003: Transcript of Technical Conference with the Electric...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    consultation Transcript of the technical conference sponsored by the U.S. Canada task force investigating the August 14, 2003 blackout across Canada and the...

  5. Method to determine transcriptional regulation pathways in organisms...

    Office of Scientific and Technical Information (OSTI)

    Title: Method to determine transcriptional regulation pathways in organisms The invention relates to computer-implemented methods and systems for identifying regulatory...

  6. Microsoft Word - ATVLMP_Transcript of 120108 Meeting.doc

    Office of Environmental Management (EM)

    Daniel Cohen Matthew McMillen Patrick Davis Advanced Technology Vehicles Manufacturing Loan Program Transcript from December 1, 2008 Public Meeting 2 TABLE OF CONTENTS...

  7. Binding of transcription factors adapts to resolve information-energy trade-off

    E-Print Network [OSTI]

    Kagan, Yonatan Savir Jacob

    2015-01-01

    We examine the binding of transcription factors to DNA in terms of an information transfer problem. The input of the noisy channel is the biophysical signal of a factor bound to a DNA site, and the output is a distribution of probable DNA sequences at this site. This task involves an inherent tradeoff between the information gain and the energetics of the binding interaction - high binding energies provide higher information gain but hinder the dynamics of the system as factors are bound too tightly. We show that adaptation of the binding interaction towards increasing information transfer under energy constraints implies that the information gain per specific binding energy at each base-pair is maximized. We analyze hundreds of prokaryote and eukaryote transcription factors from various organisms to evaluate the discrimination energies. We find that, in accordance with our theoretical argument, binding energies nearly maximize the information gain per energy. This work suggests the adaptation of information ...

  8. Find Jobs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data CenterFinancial Opportunities Financial OpportunitiesJobs Find Jobs Clean

  9. HIV transcription is induced in dying cells

    SciTech Connect (OSTI)

    Woloschak, G.E.; Chang-Liu, Chin-Mei; Schreck, S. |

    1995-06-01

    Using HeLa cells stably transfected with an HIV-LTR-CAT construct, we demonstrated a peak in CAT induction that occurs in viable (but not necessarily cell-division-competent) cells 24 h following exposure to some cell-killing agents. {gamma} rays were the only cell-killing agent which did not induce HIV transcription; this can be attributed to the fact that {gamma}-ray-induced apoptotic death requires functional p53, which is not present in HeLa cells. For all other agents, HIV-LTR induction was dose-dependent and correlated with the amount of cell killing that occurred in the culture. 14 refs., 4 figs., 1 tab.

  10. Spatial organization of bacterial transcription and translation

    E-Print Network [OSTI]

    Michele Castellana; Ned S. Wingreen

    2015-10-29

    In bacteria such as $\\textit{Escherichia coli}$, DNA is compacted into a nucleoid near the cell center, while ribosomes - molecular complexes that translate messenger RNAs (mRNAs) into proteins - are mainly localized at the poles. We study the impact of this spatial organization using a minimal reaction-diffusion model for the cellular transcriptional-translational machinery. Our model predicts that $\\sim90\\%$ of mRNAs are segregated to the poles and reveals a "circulation" of ribosomes driven by the flux of mRNAs, from synthesis in the nucleoid to degradation at the poles. To address the existence of non-specific, transient interactions between ribosomes and mRNAs, we developed a novel method to efficiently incorporate such transient interactions into reaction-diffusion equations, which allowed us to quantify the biological implications of such non-specific interactions, e.g. for ribosome efficiency.

  11. The Forkhead transcription factor Hcm1 regulates chromosome

    E-Print Network [OSTI]

    Noble, William Stafford

    cycle of budding yeast. The combined analysis of these data with three other cell cycle data sets-phase gap in the transcriptional circuitry of the cell cycle Tata Pramila,1 Wei Wu,1,2,3 Shawna Miles,1, USA Transcription patterns shift dramatically as cells transit from one phase of the cell cycle

  12. ARM - Research Highlights: Notable Findings

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Comments?govInstrumentsnoaacrnBarrow, Alaska OutreachCalendarPress ReleasesHighlightsNotable Research Findings

  13. Transcriptional Regulation in Algae, Fungi and Plants: Mating Loci, Splicing, and miRNAs

    E-Print Network [OSTI]

    Douglass, Stephen Michael

    2014-01-01

    from organisms ranging from algae to fungi and plants. WeTranscriptional Regulation in Algae, Fungi and Plants:Transcriptional Regulation in Algae, Fungi and Plants:

  14. Unraveling the Molecular Mechanism of Poly(A)-Dependent Transcription Termination

    E-Print Network [OSTI]

    Zhang, Huimin

    2014-01-01

    dependent transcription termination. Nature 463, 245–249.of transcription termination factors with the RNA polymerasecomplexes in vitro by the termination factor Rat1. J. Biol.

  15. e 2010 Keystone Symposium focusing on mechanisms of eukaryotic transcriptional regulation featured a strong

    E-Print Network [OSTI]

    Goodrich, James

    e 2010 Keystone Symposium focusing on mechanisms of eukaryotic transcriptional regulation featured of the Keystone Symposium on Dynamics of Eukaryotic Transcription during Development, Big Sky, Montana, USA, 7

  16. Regional Transmission Projects: Finding Solutions

    SciTech Connect (OSTI)

    The Keystone Center

    2005-06-15

    The Keystone Center convened and facilitated a year-long Dialogue on "Regional Transmission Projects: Finding Solutions" to develop recommendations that will help address the difficult and contentious issues related to expansions of regional electric transmission systems that are needed for reliable and economic transmission of power within and across regions. This effort brought together a cross-section of affected stakeholders and thought leaders to address the problem with the collective wisdom of their experience and interests. Transmission owners sat at the table with consumer advocates and environmental organizations. Representatives from regional transmission organizations exchanged ideas with state and federal regulators. Generation developers explored common interests with public power suppliers. Together, the Dialogue participants developed consensus solutions about how to begin unraveling some of the more intractable issues surrounding identification of need, allocation of costs, and reaching consensus on siting issues that can frustrate the development of regional transmission infrastructure. The recommendations fall into three broad categories: 1. Recommendations on appropriate institutional arrangements and processes for achieving regional consensus on the need for new or expanded transmission infrastructure 2. Recommendations on the process for siting of transmission lines 3. Recommendations on the tools needed to support regional planning, cost allocation, and siting efforts. List of Dialogue participants: List of Dialogue Participants: American Electric Power American Transmission Company American Wind Energy Association California ISO Calpine Corporation Cinergy Edison Electric Institute Environmental Defense Federal Energy Regulatory Commission Great River Energy International Transmission Company ISO-New England Iowa Public Utility Board Kanner & Associates Midwest ISO National Association of Regulatory Utility Commissioners National Association of State Utility Consumer Advocates National Grid Northeast Utilities PA Office of Consumer Advocates Pacific Gas & Electric Corporation Pennsylvania Public Utility Commission PJM Interconnection The Electricity Consumers Resource Council U.S. Department of Energy US Department of the Interior Van Ness Feldman Western Interstate Energy Board Wind on the Wires Wisconsin Public Service Commission Xcel Energy

  17. NREL Publishes Gearbox Reliability Collaborative Findings Report...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Publishes Gearbox Reliability Collaborative Findings Report NREL Publishes Gearbox Reliability Collaborative Findings Report October 3, 2011 - 12:56pm Addthis This is an excerpt...

  18. Post-transcriptional coordination by an RNA-binding protein

    E-Print Network [OSTI]

    Wolf, Joshua Jaeger

    2010-01-01

    RNA-binding proteins can regulate the stability, localization, and translation of their target mRNAs. Post-transcriptional regulation can orchestrate dynamic changes in gene expression, and can coordinate multiple cellular ...

  19. Integrated transcription and identification of named entities in broadcast speech. 

    E-Print Network [OSTI]

    Renals, Steve; Gotoh, Yoshihiko

    1999-01-01

    This paper presents an approach to integrating functions for both transcription and named entity (NE) identification into a large vocabulary continuous speech recognition system. It builds on NE tagged language modelling ...

  20. Transcriptional Regulation of Pregnane X Receptor by Protein Arginine Methyltransferase 

    E-Print Network [OSTI]

    Xie, Ying

    2011-08-08

    histone modifications such as the acetylation of histone H4. These modifications are believed to be important for transcriptional and epigenetic regulation of gene expression. We hypothesize that PRMT1 plays a role in the epigenetic changes regulated...

  1. Transcriptional regulation of taxol™ biosynthesis in taxus cuspidate procambium cells 

    E-Print Network [OSTI]

    Waibel, Thomas

    2011-11-24

    This thesis presents an investigation into the transcriptional regulation of TaxolTM biosynthsis in Taxus cuspidata cell suspension cultures. The potent anticancer drug TaxolTM has been shown to be successful in the ...

  2. The AMI System for the Transcription of Speech in Meetings 

    E-Print Network [OSTI]

    Hain, Thomas; Burget, Lukas; Dines, John; Garau, Giulia; Wan, Vincent; Karafiat, Martin; Vepa, Jithendra; Lincoln, Michael

    2007-01-01

    This paper describes the AMI transcription system for speech in meetings developed in collaboration by five research groups. The system includes generic techniques such as discriminative and speaker adaptive training, ...

  3. Host and pathogen transcriptional profiles of acute Brucella melitensis infection 

    E-Print Network [OSTI]

    Rossetti, Carlos Alberto

    2009-05-15

    The parallel gene expression profiles of Brucella melitensis and the host have not been elaborated. In this study, I analyze and discuss the transcriptional profiles of B. melitensis invasive-associated genes, the expression ...

  4. CRISPR transcriptional repression devices and layered circuits in mammalian cells

    E-Print Network [OSTI]

    Kiani, Samira

    A key obstacle to creating sophisticated genetic circuits has been the lack of scalable device libraries. Here we present a modular transcriptional repression architecture based on clustered regularly interspaced palindromic ...

  5. Multispecies diel transcriptional oscillations in open ocean heterotrophic bacterial assemblages

    E-Print Network [OSTI]

    Marin, R.

    Oscillating diurnal rhythms of gene transcription, metabolic activity, and behavior are found in all three domains of life. However, diel cycles in naturally occurring heterotrophic bacteria and archaea have rarely been ...

  6. Exploiting Elements of Transcriptional Machinery to Enhance Protein Stability

    E-Print Network [OSTI]

    Love, John J.

    Exploiting Elements of Transcriptional Machinery to Enhance Protein Stability Nora H. Barakat Ltd. All rights reserved. *Corresponding author Keywords: protein design; protein stability of protein design aspires to engineer proteins of specific function. Function is correlated directly

  7. Community Development Finance Institutions-Opportunities for Partnerships with Energy Efficiency Programs Transcript.doc

    Office of Energy Efficiency and Renewable Energy (EERE)

    Community Development Finance Institutions-Opportunities for Partnerships with Energy Efficiency Programs Transcript.doc

  8. Sustainable Energy Resources for Consumers Webinar on Solar Water Heating Transcript

    Office of Energy Efficiency and Renewable Energy (EERE)

    Video recording transcript of a Webinar on Nov. 16, 2010 about residential solar water heating applications

  9. SECONDARY SOURCES: Newspapers, Magazines, Case Summaries, Statute Summaries, News Transcripts, News

    E-Print Network [OSTI]

    Papautsky, Ian

    press releases, transcripts of television and radio shows and congressional testimony. Global Reporter

  10. Energy Savings Performance Contracting-Savings Measurement and Verification Transcript 2-24-2011.doc

    Broader source: Energy.gov [DOE]

    Energy Savings Performance Contracting-Savings Measurement and Verification Transcript 2-24-2011.doc

  11. Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Dogan, Nergiz; Wu, Weisheng; Morrissey, Christapher S.; Chen, Kuan-Bei; Stonestrom, Aaron; Long, Maria; Keller, Cheryl A.; Cheng, Yong; Jain, Deepti; Visel, Axel; et al

    2015-04-23

    Regulated gene expression controls organismal development, and variation in regulatory patterns has been implicated in complex traits. Thus accurate prediction of enhancers is important for further understanding of these processes. Genome-wide measurement of epigenetic features, such as histone modifications and occupancy by transcription factors, is improving enhancer predictions, but the contribution of these features to prediction accuracy is not known. Given the importance of the hematopoietic transcription factor TAL1 for erythroid gene activation, we predicted candidate enhancers based on genomic occupancy by TAL1 and measured their activity. Contributions of multiple features to enhancer prediction were evaluated based on the resultsmore »of these and other studies. Results: TAL1-bound DNA segments were active enhancers at a high rate both in transient transfections of cultured cells (39 of 79, or 56%) and transgenic mice (43 of 66, or 65%). The level of binding signal for TAL1 or GATA1 did not help distinguish TAL1-bound DNA segments as active versus inactive enhancers, nor did the density of regulation-related histone modifications. A meta-analysis of results from this and other studies (273 tested predicted enhancers) showed that the presence of TAL1, GATA1, EP300, SMAD1, H3K4 methylation, H3K27ac, and CAGE tags at DNase hypersensitive sites gave the most accurate predictors of enhancer activity, with a success rate over 80% and a median threefold increase in activity. Chromatin accessibility assays and the histone modifications H3K4me1 and H3K27ac were sensitive for finding enhancers, but they have high false positive rates unless transcription factor occupancy is also included. Conclusions: Occupancy by key transcription factors such as TAL1, GATA1, SMAD1, and EP300, along with evidence of transcription, improves the accuracy of enhancer predictions based on epigenetic features.« less

  12. MFR PAPER 1230 Finding Fish With Satellites

    E-Print Network [OSTI]

    sensors, fishing vessels , spotter pilots, research vessels, and offshore oil platforms were used Investigation? A. It is an attempt to find out if satellites can help fishermen find fish. Our assumption

  13. Trigger loop folding determines transcription rate of Escherichia coli’s RNA polymerase

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Mejia, Yara X.; Nudler, Evgeny; Bustamante, Carlos

    2014-12-31

    Two components of the RNA polymerase (RNAP) catalytic center, the bridge helix and the trigger loop (TL), have been linked with changes in elongation rate and pausing. Here, single molecule experiments with the WT and two TL-tip mutants of the Escherichia coli enzyme reveal that tip mutations modulate RNAP’s pause-free velocity, identifying TL conformational changes as one of two rate-determining steps in elongation. Consistent with this observation, we find a direct correlation between helix propensity of the modified amino acid and pause-free velocity. Moreover, nucleotide analogs affect transcription rate, suggesting that their binding energy also influences TL folding. A kineticmore »model in which elongation occurs in two steps, TL folding on nucleoside triphosphate (NTP) binding followed by NTP incorporation/pyrophosphate release, quantitatively accounts for these results. The TL plays no role in pause recovery remaining unfolded during a pause. The model suggests a finely tuned mechanism that balances transcription speed and fidelity.« less

  14. RNF43 interacts with NEDL1 and regulates p53-mediated transcription

    SciTech Connect (OSTI)

    Shinada, Keisuke [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan) [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan); Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638 (Japan); Tsukiyama, Tadasuke [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan)] [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan); Sho, Takuya [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan) [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan); Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638 (Japan); Okumura, Fumihiko [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan)] [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan); Asaka, Masahiro [Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638 (Japan)] [Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638 (Japan); Hatakeyama, Shigetsugu, E-mail: hatas@med.hokudai.ac.jp [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan)] [Department of Biochemistry, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638 (Japan)

    2011-01-07

    Research highlights: {yields} RNF43 binds to NEDD-4-like ubiquitin-protein ligase-1 (NEDL1). {yields} RNF43 interacts with p53 and suppresses transcriptional activity of p53. {yields} RNF43 attenuates apoptosis induced by ultraviolet irradiation. {yields} RNF43 is likely associated with p53-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis. -- Abstract: The ubiquitin-proteasomal system plays a crucial role in oncogenesis in colorectal tissues. Recent studies have shown that stability of {beta}-catenin, which functions as an oncogene for colorectal cancer, is regulated by ubiquitin-mediated degradation. It has been reported that a putative E3 ubiquitin ligase, RNF43, is highly expressed in human colorectal carcinoma and that RNF43 promotes cell growth. However, the involvement of RNF43 in carcinogenesis has not been fully elucidated. In this study, we found by using yeast two-hybrid screening that RNF43 binds to NEDD-4-like ubiquitin-protein ligase-1 (NEDL1), which enhances pro-apoptotic activity by p53. In addition, we found that RNF43 also interacts with p53 and that RNF43 suppresses transcriptional activity of p53 in H1299 cells and attenuates apoptosis induced by ultraviolet irradiation. These findings suggest that RNF43 is associated with p53-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis.

  15. Trigger loop folding determines transcription rate of Escherichia coli’s RNA polymerase

    SciTech Connect (OSTI)

    Mejia, Yara X. [Univ. of California, Berkeley, CA (United States); Nudler, Evgeny [New York Univ. School of Medicine, New York, NY (United States); Bustamante, Carlos [Univ. of California, Berkeley, CA (United States); Kavli Energy Nanosciences Institute at Berkeley, Berkeley, CA (United States)

    2014-12-31

    Two components of the RNA polymerase (RNAP) catalytic center, the bridge helix and the trigger loop (TL), have been linked with changes in elongation rate and pausing. Here, single molecule experiments with the WT and two TL-tip mutants of the Escherichia coli enzyme reveal that tip mutations modulate RNAP’s pause-free velocity, identifying TL conformational changes as one of two rate-determining steps in elongation. Consistent with this observation, we find a direct correlation between helix propensity of the modified amino acid and pause-free velocity. Moreover, nucleotide analogs affect transcription rate, suggesting that their binding energy also influences TL folding. A kinetic model in which elongation occurs in two steps, TL folding on nucleoside triphosphate (NTP) binding followed by NTP incorporation/pyrophosphate release, quantitatively accounts for these results. The TL plays no role in pause recovery remaining unfolded during a pause. The model suggests a finely tuned mechanism that balances transcription speed and fidelity.

  16. Math 453 Abstract Algebra sample 1. Find gcd(123,745) 2. Find the ...

    E-Print Network [OSTI]

    2015-09-18

    Math 453 Abstract Algebra sample. 1. Find gcd(123,745). 2. Find the inverse of 23 in Z71. 3. Find the last two digits of 15100. 4. Prove that the set of all 2 × 2 ...

  17. Customized optimization of metabolic pathways by combinatorial transcriptional engineering

    E-Print Network [OSTI]

    Zhao, Huimin

    Engineering, Institute for Genomic Biology and 2 Departments of Chemistry, Biochemistry and BioengineeringCustomized optimization of metabolic pathways by combinatorial transcriptional engineering Jing Du1, 2012; Accepted May 15, 2012 ABSTRACT A major challenge in metabolic engineering and syn- thetic biology

  18. Mechanism Based Anticancer Drugs that Degrade Sp Transcription Factors 

    E-Print Network [OSTI]

    Chadalapaka, Gayathri

    2013-03-14

    4 transcription factors. Similar results were observed for a structurally-related triterpenoid, methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate (CDDO-Me), which is currently in clinical trials for treatment of leukemia. Celastrol, a naturally...

  19. Global Entrainment of Transcriptional Systems to Periodic Inputs

    E-Print Network [OSTI]

    Sontag, Eduardo

    of models of transcriptional systems as well as constructs of interest in synthetic biology. A self permits unrestricted use, distribution, and reproduction in any medium, provided the original author from the environment that then acts as a pacemaker [1]. Moreover, such an entrainment can be obtained

  20. Transcriptional regulation constrains the organization of genes on eukaryotic chromosomes

    E-Print Network [OSTI]

    Babu, M. Madan

    . In particular, we reveal that the target genes (TGs) of transcription factors (TFs) for the yeast, Saccharo show that (i) the TGs of a majority of TFs show a strong preference to be encoded on specific chromosomes, (ii) the TGs of a significant number of TFs display a strong preference (or avoidance

  1. Edinburgh Research Explorer Analysis of the transcriptional networks underpinning the

    E-Print Network [OSTI]

    MacDonald, Andrew

    of murine macrophages by inflammatory mediators Citation for published version: Raza, S, Barnett, MW, Barnett-Itzhaki, Z, Amit, I, Hume, DA & Freeman, TC 2014, 'Analysis of the transcriptional networks macrophages by inflammatory mediators Sobia Raza,* Mark W. Barnett,* Zohar Barnett-Itzhaki, Ido Amit, David A

  2. Dissecting the transcription networks of a cell using computational genomics

    E-Print Network [OSTI]

    Babu, M. Madan

    Dissecting the transcription networks of a cell using computational genomics Hao Lià and Wei Wangy A great challenge in understanding biological complexity in the post-genome era is to reconstruct of genomic sequence and functional data has led to the development of computational approaches

  3. Chemical Profile Hepatic Transcriptional Networks Induced by Exposure to

    E-Print Network [OSTI]

    Bradfield, Christopher A.

    Chemical Profile Hepatic Transcriptional Networks Induced by Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) serves as a prototype for a range of environmental toxicants The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) has long been a focus of public concern. Formed

  4. Group Non-negative Basis Pursuit for Automatic Music Transcription

    E-Print Network [OSTI]

    Plumbley, Mark

    Group Non-negative Basis Pursuit for Automatic Music Transcription Ken O'Hanlon1 , Mark D. Plumbley1 {keno, Mark.Plumbley}@eecs.qmul.ac.uk Centre for Digital Music, Queen Mary University of London for AMT (O'Hanlon et al.). Group sparsity considers that certain groups of atoms tend to be ac- tive

  5. Transcriptional Targeting for Ovarian Cancer Gene Therapy E. Casado,*,

    E-Print Network [OSTI]

    Hemminki, Akseli

    REVIEW Transcriptional Targeting for Ovarian Cancer Gene Therapy E. Casado,*, D. M. Nettelbeck Paz, Madrid, Spain Received November 10, 2000 Ovarian carcinoma is a leading cause of cancer death patients diagnosed with ovarian cancer are still low. Therefore, novel molecular therapeutic strat- egies

  6. Battelle Columbus Laboratories Director's Final Findings and...

    Office of Environmental Management (EM)

    Name Battelle Columbus Laboratories Director's Final Findings and Orders, October 4, 1995 State Ohio Agreement Type Federal Facility Agreement Legal Driver(s) FFCAct Scope...

  7. Portsmouth Gaseous Diffusion Plant Director's Final Findings...

    Office of Environmental Management (EM)

    Portsmouth Gaseous Diffusion Plant Director's Final Findings and Orders, October 4, 1995 State Ohio Agreement Type Federal Facility Agreement Legal Driver(s) FFCAct Scope Summary...

  8. Timed Nuclear Import of a Transcription Factor During Erythropoiesis Erythroid Krppel-like factor (EKLF) is an erythroid transcription factor

    E-Print Network [OSTI]

    Chen, Sheng-Wei

    Timed Nuclear Import of a Transcription Factor During Erythropoiesis Erythroid Krüppel-like factor. The regulatory mechanisms of the nuclear transport of EKLF during erythroid differentiation have remained unclear provided essential new insights into this process. They show that nuclear import of EKLF in erythroid cells

  9. Genomes & Developmental Control Isl1 is a direct transcriptional target of Forkhead transcription factors in second heart

    E-Print Network [OSTI]

    factors in second heart field-derived mesoderm Jione Kang a , Elisha Nathan b , Shan-Mei Xu a , Eldad 2009 Available online 4 July 2009 Keywords: Isl1 Second heart field Anterior heart field Transgenic Transcription factor Forkhead FoxC2 FoxA2 FoxF1 Mouse The cells of the second heart field (SHF) contribute

  10. Transcription Factor IID Recruitment and Sp1 Activation DUAL FUNCTION OF TAF1 IN CYCLIN D1 TRANSCRIPTION*

    E-Print Network [OSTI]

    Wang, Edith

    kinases, an event necessary to drive cells through the proliferation cycle (1). Cyclin protein levels-7280 Cyclin D1 is an oncogene that regulates progression through the G1 phase of the cell cycle. A temperature to arrest in late G1 by decreasing transcription of cell cycle regula- tors, including cyclin D1. Here we

  11. Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma

    E-Print Network [OSTI]

    Litonjua, Augusto A.

    Background: Identifying genetic determinants for lung function is important in providing insight into the pathophysiology of asthma. Signal transducer and activator of transcription 3 is a transcription factor latent in ...

  12. A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase

    E-Print Network [OSTI]

    Segall-Shapiro, Thomas Hale

    Synthetic genetic systems share resources with the host, including machinery for transcription and translation. Phage RNA polymerases (RNAPs) decouple transcription from the host and generate high expression. However, they ...

  13. Influence of RNA Polymerase II Catalytic Activity on Transcription Start Site Selection 

    E-Print Network [OSTI]

    Jin, Huiyan

    2015-08-01

    catalytic activity influences the first step of gene expression, transcription initiation, in Saccharomyces cerevisiae. My dissertation focuses on the mechanisms by which Pol II activity defects contribute to transcription start site (TSS) selection...

  14. The Ets Transcription Factor EHF as a Regulator of Cornea Epithelial Cell Identity*

    E-Print Network [OSTI]

    Stephens, Denise N.; Klein, Rachel Herndon; Salmans, Michael L.; Gordon, William; Ho, Hsiang; Andersen, Bogi

    2013-01-01

    young adult (average of P28 and P60) and old (2-year) mice.old mice, identifying the most abundantly expressed transcripts, transcriptional regulators, and enriched gene groups in the developing and adult

  15. Tunable and Multifunctional Eukaryotic Transcription Factors Based on CRISPR/Cas

    E-Print Network [OSTI]

    Farzadfard, Fahim

    Transcriptional regulation is central to the complex behavior of natural biological systems and synthetic gene circuits. Platforms for the scalable, tunable, and simple modulation of transcription would enable new abilities ...

  16. G:\\envplanning\\LRDP\\Final EIR\\findings_NODs\\LRDP Findings.doc 11/24/03 CERTIFICATION OF THE FINAL EIR, FINDINGS, AND APPROVAL OF

    E-Print Network [OSTI]

    Ullrich, Paul

    G:\\envplanning\\LRDP\\Final EIR\\findings_NODs\\LRDP Findings.doc 11/24/03 CERTIFICATION OF THE FINAL LRDP CEQA FINDINGS PAGE 2 G:\\envplanning\\LRDP\\Final EIR\\findings_NODs\\LRDP Findings.doc 11

  17. Finding Hierarchical Heavy Hitters in Data Streams

    E-Print Network [OSTI]

    Cormode, Graham

    . The problem we study in this paper is that of finding Hierarchical Heavy Hitters (HHH): given a hierarchy and a fraction , we want to find all HHH nodes that have a total num- ber of descendants in the data stream that are HHH nodes. The resulting summary gives a topological "cartogram" of the hierarchical data. We present

  18. Experiences Using Static Analysis to Find Bugs

    E-Print Network [OSTI]

    Cortes, Corinna

    , FindBugs, code quality, bug patterns, software defects, software quality ! 1 INTRODUCTION SOFTWARE to improve software quality, including testing, code review, and for- mal specification. Find with relatively simple techniques and to help us understand how such tools can be incorporated into the software

  19. ANNUAL CONFERENCE ON SUCCESSFUL AGING FINDING BALANCE

    E-Print Network [OSTI]

    3RD ANNUAL CONFERENCE ON SUCCESSFUL AGING FINDING BALANCE: ENHANCING PHYSICAL, EMOTIONAL, and how to improve them. Finding Balance Supports Our Well-Being. Dr. Glisky will talk about how balance in humans; Evolutionary medicine. Balance Exercises and Fitness to Prevent Injuries and Cognitive Decline

  20. Find us on Facebook myscienceacademy.org

    E-Print Network [OSTI]

    Chiao, Jung-Chih

    Find us on Facebook myscienceacademy.org 144,123 people like myscienceacademy.org. Facebook social In Recommendations Log in to Facebook to see your friends' recommendations. 24 Places That Look Not Normal, But Are Actually Real 183,768 people recommend this. NASA rover Curiosity finds water in Mars s report 1,823 people

  1. Meeting of the Electricity Advisory Committee Meeting, September 29-30, 2015- Meeting Minutes and Transcripts

    Broader source: Energy.gov [DOE]

    Meeting minutes and transcripts for the September 29-30, 2015 meeting of the Electric Advisory Committee.

  2. Sustainable Energy Resources for Consumers Webinar on Residential Geothermal Heat Pump Retrofit Transcript

    Broader source: Energy.gov [DOE]

    Transcript for a U.S. Department of Energy Webinar on Dec. 14, 2010, about residential geothermal heat pump retrofits

  3. TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies

    E-Print Network [OSTI]

    regulatory elements. They include cis-elements, such as promoters and trans-elements, such as transcription

  4. Transcriptional leakage versus noise: A simple mechanism of conversion between binary and graded response in autoregulated genes

    E-Print Network [OSTI]

    Anna Ochab-Marcinek; Marcin Tabaka

    2015-01-16

    We study the response of an autoregulated gene to a range of concentrations of signal molecules. We show that transcriptional leakage and noise due to translational bursting have the opposite effects. In a positively autoregulated gene, increasing the noise converts the response from graded to binary, while increasing the leakage converts the response from binary to graded. Our findings support the hypothesis that, being a common phenomenon, leaky expression may be a relatively easy way for evolutionary tuning of the type of gene response without changing the type of regulation from positive to negative.

  5. ISIS Assistant 9.0 | Official Transcript Request Created: 04.29.13

    E-Print Network [OSTI]

    Capogna, Luca

    ISIS Assistant 9.0 | Official Transcript Request Created: 04.29.13 ISIS Assistant Official Center page and select the direct link to the request page. #12;ISIS Assistant 9.0 | Official Transcript Request Created: 04.29.13 ISIS Assistant Official Transcript Request Student Center 3. From the Official

  6. Transcriptional control in Alicyclobacillus acidocaldarius and associated genes, proteins, and methods

    DOE Patents [OSTI]

    Lee, Brady Deneys; Thompson, David N; Apel, William A.; Thompson, Vicki Slavchev; Reed, David W; Lacey, Jeffrey A

    2014-05-06

    Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.

  7. APOLLO 17 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE

    E-Print Network [OSTI]

    Rathbun, Julie A.

    APOLLO 17 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE #12;APOLLO 17 VOICE TRANSCRIPT Pertaining to the geology of the landing site by N.G. Bai ley and G.E. Ulrich U.s. Geological 5. Report Date Apollo 17 Voice Transcript 1975 Pertaining to the Geology of the Landing Site 6. 7

  8. Yeast GCN4 as a probe for oncogenesis by AP-1. transcription factors

    E-Print Network [OSTI]

    Yeast GCN4 as a probe for oncogenesis by AP-1. transcription factors: transcnpuonal activation for oncogenesis but are distinct from generic transcriptional activation domains. In addition, these observations. IKey Words: Yeast GCN4; Jun; Fos; AP-1 transcription factors; oncogenesis; cellular transformation

  9. RESEARCH Open Access Cell type-specific termination of transcription by

    E-Print Network [OSTI]

    Jordan, King

    RESEARCH Open Access Cell type-specific termination of transcription by transposable element sequences necessary for their own transposition, including signals required for the termination to terminate the transcription of host gene transcripts. While there is evidence in support of this model

  10. Physical properties of naked DNA influence nucleosome positioning and correlate with transcription start and termination sites in yeast

    E-Print Network [OSTI]

    Deniz, Özgen; Flores, Oscar; Battistini, Federica; Pérez, Alberto; Soler-López, Montserrat; Orozco, Modesto

    2011-01-01

    with transcription start and termination sites in yeast. BMCtranscription start and termination sites in yeast Özgenand TTS (Transcription Termination Site) (at least in yeast)

  11. Transcript Request Form Note that any current or former student with a UTLN may request a transcript through iSIS at

    E-Print Network [OSTI]

    Dennett, Daniel

    a transcript through iSIS at http://go.tufts.edu/isis Please complete this form to request a Sackler School

  12. Efficiency and versatility of distal multisite transcription regulation

    E-Print Network [OSTI]

    Leonor Saiz; Jose M. G. Vilar

    2007-04-24

    Transcription regulation typically involves the binding of proteins over long distances on multiple DNA sites that are brought close to each other by the formation of DNA loops. The inherent complexity of the assembly of regulatory complexes on looped DNA challenges the understanding of even the simplest genetic systems, including the prototypical lac operon. Here we implement a scalable quantitative computational approach to analyze systems regulated through multiple DNA sites with looping. Our approach applied to the lac operon accurately predicts the transcription rate over five orders of magnitude for wild type and seven mutants accounting for all the combinations of deletions of the three operators. A quantitative analysis of the model reveals that the presence of three operators provides a mechanism to combine robust repression with sensitive induction, two seemingly mutually exclusive properties that are required for optimal functioning of metabolic switches.

  13. Switched Dynamical Latent Force Models for Modelling Transcriptional Regulation

    E-Print Network [OSTI]

    López-Lopera, Andrés F

    2015-01-01

    In order to develop statistical approaches for transcription networks, statistical community has proposed several methods to infer activity levels of proteins, from time-series measurements of targets' expression levels. A few number of approaches have been proposed in order to outperform the representation of fast switching time instants, but computational overheads are significant due to complex inference algorithms. Using the theory related to latent force models (LFM), the development of this project provide a switched dynamical hybrid model based on Gaussian processes (GPs). To deal with discontinuities in dynamical systems (or latent driving force), an extension of the single input motif approach is introduced, that switches between different protein concentrations, and different dynamical systems. This creates a versatile representation for transcription networks that can capture discrete changes and non-linearities in the dynamics. The proposed method is evaluated on both simulated data and real data,...

  14. Comparative genomics of transcriptional regulation of methionine metabolism in proteobacteria

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Leyn, Semen A.; Suvorova, Inna A.; Kholina, Tatiana D.; Sherstneva, Sofia S.; Novichkov, Pavel S.; Gelfand, Mikhail S.; Rodionov, Dmitry A.; Kuipers, Oscar P.

    2014-11-20

    Methionine metabolism and uptake genes in Proteobacteria are controlled by a variety of RNA and DNA regulatory systems. We have applied comparative genomics to reconstruct regulons for three known transcription factors, MetJ, MetR, and SahR, and three known riboswitch motifs, SAH, SAM-SAH, and SAM_alpha, in ~200 genomes from 22 taxonomic groups of Proteobacteria. We also identified two novel regulons: a SahR-like transcription factor SamR controlling various methionine biosynthesis genes in the Xanthomonadales group, and a potential RNA regulatory element with terminator-antiterminator mechanism controlling the metX or metZ genes in beta-proteobacteria. For each analyzed regulator we identified the core, taxon-specific andmore »genome-specific regulon members. By analyzing the distribution of these regulators in bacterial genomes and by comparing their regulon contents we elucidated possible evolutionary scenarios for the regulation of the methionine metabolism genes in Proteobacteria.« less

  15. The transcriptional diversity of 25 Drosophila cell lines

    SciTech Connect (OSTI)

    Cherbas, Lucy; Willingham, Aarron; Zhang, Dayu; Yang, Li; Zou, Yi; Eads, Brian D.; Carlson, Joseph W.; Landolin, Jane M.; Kapranov, Philipp; Dumais, Jacqueline; Samsonova, Anastasia; Choi, Jeong-Hyeon; Roberts, Johnny; Davis, Carrie A.; Tang, Haixu; van Baren, Marijke J.; Ghosh, Srinka; Dobin, Alexander; Bell, Kim; Lin, Wei; Langton, Laura; Duff, Michael O.; Tenney, Aaron E.; Zaleski, Chris; Brent, Michael R.; Hoskins, Roger A.; Kaufman, Thomas C.; Andrews, Justen; Graveley, Brenton R.; Perrimon, Norbert; Celniker, Susan E.; Gingeras, Thomas R.; Cherbas, Peter

    2010-11-15

    Drosophila melanogaster cell lines are important resources for cell biologists. Here, we catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines. Unannotated transcription is substantial (typically 19% of euchromatic signal). Conservatively, we identify 1405 novel transcribed regions; 684 of these appear to be new exons of neighboring, often distant, genes. Sixty-four percent of genes are expressed detectably in at least one line, but only 21% are detected in all lines. Each cell line expresses, on average, 5885 genes, including a common set of 3109. Expression levels vary over several orders of magnitude. Major signaling pathways are well represented: most differentiation pathways are ‘‘off’’ and survival/growth pathways ‘‘on.’’ Roughly 50% of the genes expressed by each line are not part of the common set, and these show considerable individuality. Thirty-one percent are expressed at a higher level in at least one cell line than in any single developmental stage, suggesting that each line is enriched for genes characteristic of small sets of cells. Most remarkable is that imaginal discderived lines can generally be assigned, on the basis of expression, to small territories within developing discs. These mappings reveal unexpected stability of even fine-grained spatial determination. No two cell lines show identical transcription factor expression. We conclude that each line has retained features of an individual founder cell superimposed on a common ‘‘cell line‘‘ gene expression pattern. Wereport the transcriptional profiles of 25 Drosophila melanogaster cell lines, principally by whole-genome tiling microarray analysis of total RNA, carried out as part of the modENCODE project. The data produced in this study add to our knowledge of the cell lines and of the Drosophila transcriptome in several ways. We summarize the expression of previously annotated genes in each of the 25 lines with emphasis on what those patterns reveal about the origins of the lines and the stability of spatial expression patterns. We also offer an initial analysis of previously unannotated transcripts in the cell lines.

  16. Finding Hidden Oil and Gas Reserves

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &ReportseBooks FindFinding

  17. Finding Algorithms in Scientific Articles Sumit Bhatia

    E-Print Network [OSTI]

    Giles, C. Lee

    Finding Algorithms in Scientific Articles Sumit Bhatia , Prasenjit Mitra and C. Lee Giles,giles}@ist.psu.edu ABSTRACT Algorithms are an integral part of computer science literature. How- ever, none of the current search engines offer specialized algorithm search facility. We describe a vertical search engine

  18. Brain Imaging Findings in Neuropathic Pain

    E-Print Network [OSTI]

    Apkarian, A. Vania

    Brain Imaging Findings in Neuropathic Pain Paul Y. Geha, MD and A. Vania Apkarian, PhD* Address (posther- petic neuralgia), then the spinal cord (postspinal cord injury pain), to the brain itself mechanisms; hence, they assume implicitly or explicitly that the rest of the brain passively responds

  19. Application Deadline: Where you'll find

    E-Print Network [OSTI]

    de Leon, Alex R.

    Application Deadline: January 15 Where you'll find some of our alumni · PhD (Mathematical Finance and operations research, with applications to biology, energy finance, geoscience and medicine · Number theory, and applications to biology, medicine and oil & gas industry You could be working on these research problems

  20. Automated Filament Finding and Selection from Cryo

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Automated Filament Finding and Selection from Cryo Electron Micrographs Y. Zhu, B. Carragher, and C N Mathews Urbana, IL 61801 techreports@itg.uiuc.edu http://www.itg.uiuc.edu #12;AUTOMATED FILAMENT and selecting filamentous structures from images of this kind. Images are acquired in defocus pairs; a near

  1. Vermont's Changing Forests Key Findings on the

    E-Print Network [OSTI]

    Keeton, William S.

    1 Vermont's Changing Forests Key Findings on the Health of Forested Ecosystems from the Vermont Members Anne Archie, USDA Forest Service Douglas Lantagne, University of Vermont Ed O'Leary, Vermont, USDA Farm Service Agency Charles Scott, USDA Forest Service Steven Sinclair, Vermont Agency of Natural

  2. Atlas Finding Aid Contents/Index

    E-Print Network [OSTI]

    Ward, Karen

    Atlas Finding Aid Contents/Index A (1) City & State Atlas A (2) Astronomy Atlas A (3) U.S. Atlas A (4) Water Atlas A (5) South America & Central America A (6) Africa, Asia, &, Antarctica A (7) Mexico) SAN ANTONIO QUICK FINDER MAPS F 1373 .B46 F4 1990 33. A (1) SURFACE WATER RESOURCES OF TEXAS MAPS G

  3. Finding Music Scores with Library Search

    E-Print Network [OSTI]

    Chrispell, John

    Multiple Sources from the menu, enter your search terms, and click the green magnifying glass to search in the Popular Resources box. Enter your search terms, limit to Music Scores, then click Search. Click the titleFinding Music Scores with Library Search BEGIN YOUR SEARCH AT http://library.tulane.edu Select

  4. Transcriptional diversity during lineage commitment of human blood progenitors

    E-Print Network [OSTI]

    Chen, Lu; Kostadima, Myrto; Martens, Joost H.A.; Canu, Giovanni; Garcia, Sara P.; Turro, Ernest; Downes, Kate; Macaulay, Iain C.; Bielczyk-Maczynska, Ewa; Coe, Sophia; Farrow, Samantha; Poudel, Pawan; Burden, Frances; Jansen, Sjoert B.G.; Astle, William J.; Attwood, Antony; Bariana, Tadbir; de Bono, Bernard; Breschi, Alessandra; Chambers, John C.; BRIDGE Consortium; Choudry, Fizzah A.; Clarke, Laura; Coupland, Paul; van der Ent, Martijn; Erber, Wendy N.; Jansen, Joop H.; Favier, Rémi; Fenech, Matthew E.; Foad, Nicola; Freson, Kathleen; van Geet, Chris; Gomez, Keith; Guigo, Roderic; Hampshire, Daniel; Kelly, Anne M.; Kerstens, Hindrik H.D.; Kooner, Jaspal S.; Laffan, Michael; Lentaigne, Claire; Labalette, Charlotte; Martin, Tiphaine; Meacham, Stuart; Mumford, Andrew; Nürnberg, Sylvia; Palumbo, Emilio; van der Reijden, Bert A.; Richardson, David; Sammut, Stephen J.; Slodkowicz, Greg; Tamuri, Asif U.; Vasquez, Louella; Voss, Katrin; Watt, Stephen; Westbury, Sarah; Flicek, Paul; Loos, Remco; Goldman, Nick; Bertone, Paul; Read, Randy J.; Richardson, Sylvia; Cvejic, Ana; Soranzo, Nicole; Ouwehand, Willem H.; Stunnenberg, Hendrik G.; Frontini, Mattia; Rendon, Augusto

    2014-09-26

    significance using a likelihood ratio test. The beta binomial model accounts for the overdispersion - beyond the expected binomial variance - present in the data. It is an extension to the binomial model (i.e. logistic regression) and is akin to using a... and densitometry performed. PacBio libraries were generated (Pacific Biosciences, Menlo Park, CA) from cDNA obtained by reverse transcription of 10 ng of MK_3 total RNA and sequenced in five SMRTcells on the PacBio RSII. SMRTpipe and ICE were used to filter...

  5. Transcriptional functions of the corepressor Sin3A in skin

    E-Print Network [OSTI]

    Cox, Claire

    2013-03-12

    by the fact that disruption of their expression leads to skin disease. For example, a number of members of the S100 gene family have been observed to be up-regulated in psoriasis and skin cancer [Hoffjan and Stemmler, 2007]. Disruption of the expression... of genes in the Flg-like, LCE and SPRR families has been linked with the development of atopic dermatitis and psoriasis as well as ichthyosis vulgaris [de Guzman Strong et al., 2010]. A number of transcription factors have been implicated in the control...

  6. Engineering phenolics metabolism in the grasses using transcription factors

    SciTech Connect (OSTI)

    Grotewold, Erich [The Ohio State University

    2013-07-26

    The economical competitiveness of agriculture-derived biofuels can be significantly enhanced by increasing biomass/acre yields and by furnishing the desired carbon balance for facilitating liquid fuel production (e.g., ethanol) or for high-energy solid waste availability to be used as biopower (e.g., for electricity production). Biomass production and carbon balance are tightly linked to the biosynthesis of phenolic compounds, which are found in crops and in agricultural residues either as lignins, as part of the cell wall, or as soluble phenolics which play a variety of functions in the biology of plants. The grasses, in particular maize, provide the single major source of agricultural biomass, offering significant opportunities for increasing renewable fuel production. Our laboratory has pioneered the use of transcription factors for manipulating plant metabolic pathways, an approach that will be applied here towards altering the composition of phenolic compounds in maize. Previously, we identified a small group of ten maize R2R3-MYB transcription factors with all the characteristics of regulators of different aspects of phenolic biosynthesis. Here, we propose to investigate the participation of these R2R3-MYB factors in the regulation of soluble and insoluble maize phenolics, using a combination of over-expression and down-regulation of these transcription factors in transgenic maize cultured cells and in maize plants. Maize cells and plants altered in the activity of these regulatory proteins will be analyzed for phenolic composition by targeted metabolic profiling. Specifically, we will I) Investigate the effect of gain- and loss-of-function of a select group of R2R3-MYB transcription factors on the phenolic composition of maize plants and II) Identify the biosynthetic genes regulated by each of the selected R2R3-MYB factors. While a likely outcome of these studies are transgenic maize plants with altered phenolic composition, this research will significantly contribute to understanding how different branches of the phenolic biosynthetic grid are regulated. Given the conservation of the selected regulators in other grasses, results derived from this project are likely to provide important tools for the manipulation of phenolic compounds in other emerging biomass producers (e.g., switchgrass or miscanthus), either through conventional breeding techniques (e.g., marker-assisted breeding) or by using transgenic approaches.

  7. Transcriptional regulatory network for sexual differentiation in fission yeast

    E-Print Network [OSTI]

    Mata, Juan; Wilbrey, Anna; Bahler, Jurg

    2007-10-10

    2H2-type zinc fingers that are induced in middle/late meiosis (Figures 3a and 4a). Rsv1p has previously been reported to be required for maintaining viability in stationary phase cells; in particular, Rsv1p is required to prevent the loss... Open Access2007Mataet l.Volume 8, Issue 10, Article R217Research Transcriptional regulatory network for sexual differentiation in fission yeast Juan Mata*†, Anna Wilbrey*‡ and Jürg Bähler* Addresses: *Cancer Research UK Fission Yeast Functional...

  8. Commercial Building Energy Asset Score: Pilot Findings and Program...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Score: Pilot Findings and Program Update Commercial Building Energy Asset Score: Pilot Findings and Program Update The webinar was held on April 16, 2014, to share the findings...

  9. Finite Model Finding for Parameterized Verification

    E-Print Network [OSTI]

    Lisitsa, Alexei

    2010-01-01

    In this paper we investigate to which extent a very simple and natural "reachability as deducibility" approach, originated in the research in formal methods in security, is applicable to the automated verification of large classes of infinite state and parameterized systems. The approach is based on modeling the reachability between (parameterized) states as deducibility between suitable encodings of states by formulas of first-order predicate logic. The verification of a safety property is reduced to a pure logical problem of finding a countermodel for a first-order formula. The later task is delegated then to the generic automated finite model building procedures. In this paper we first establish the relative completeness of the finite countermodel finding method (FCM) for a class of parameterized linear arrays of finite automata. The method is shown to be at least as powerful as known methods based on monotonic abstraction and symbolic backward reachability. Further, we extend the relative completeness of ...

  10. Comparative genomics of transcriptional regulation of methionine metabolism in proteobacteria

    SciTech Connect (OSTI)

    Leyn, Semen A.; Suvorova, Inna A.; Kholina, Tatiana D.; Sherstneva, Sofia S.; Novichkov, Pavel S.; Gelfand, Mikhail S.; Rodionov, Dmitry A.; Kuipers, Oscar P.

    2014-11-20

    Methionine metabolism and uptake genes in Proteobacteria are controlled by a variety of RNA and DNA regulatory systems. We have applied comparative genomics to reconstruct regulons for three known transcription factors, MetJ, MetR, and SahR, and three known riboswitch motifs, SAH, SAM-SAH, and SAM_alpha, in ~200 genomes from 22 taxonomic groups of Proteobacteria. We also identified two novel regulons: a SahR-like transcription factor SamR controlling various methionine biosynthesis genes in the Xanthomonadales group, and a potential RNA regulatory element with terminator-antiterminator mechanism controlling the metX or metZ genes in beta-proteobacteria. For each analyzed regulator we identified the core, taxon-specific and genome-specific regulon members. By analyzing the distribution of these regulators in bacterial genomes and by comparing their regulon contents we elucidated possible evolutionary scenarios for the regulation of the methionine metabolism genes in Proteobacteria.

  11. http://www.patent.gov.uk/patent/p-find/p-find-number Patents status information

    E-Print Network [OSTI]

    Colquhoun, David

    http://www.patent.gov.uk/patent/p-find/p-find-number Patents status information FULL DETAILS2409644 dated 06.07.2005 Examination requested 31.12.2004 Grant of Patent (Notification under Section 18(4)) 22.11.2005 Publication of notice in the Patents and Designs Journal (Section 25(1)) 21.12.2005 Title

  12. Resources for Handling Transcripts | U.S. DOE Office of Science...

    Office of Science (SC) Website

    DOE Laboratories and Points of Contact Information for Laboratory Scientists and Thesis Advisors Key Dates Frequently Asked Questions Contact WDTS Home Graduate Transcripts...

  13. Connectivity in the Yeast Cell Cycle Transcription Network: Inferences from Neural Networks

    E-Print Network [OSTI]

    Hart, Christopher E; Mjolsness, Eric; Wold, Barbara J

    2006-01-01

    Issue 12 | e169 Neural Network Model of Yeast Transcription27. Bishop C (1995) Neural networks for pattern recognition.Network: Inferences from Neural Networks Christopher E. Hart

  14. Transcript of April 3, 2013, TAP webinar titled State Energy Strategic Planning

    Office of Energy Efficiency and Renewable Energy (EERE)

    U.S. Department of Energy (DOE) Technical Assistance Program (TAP) transcript of a TAP webinar held on April 3, 2013 and dealing with state energy strategic planning.

  15. Sustainable Energy Resources for Consumers Webinar on Building Design & Passive Solar Transcript

    Broader source: Energy.gov [DOE]

    Video recording transcript of a Webinar on Nov. 16, 2010 about residential passive solar building design and solar thermal heating applications

  16. Successful Partnerships and Lessons from the Field, Part 1, Webinar Transcript

    Broader source: Energy.gov [DOE]

    Part 1-Successful Partnerships and Lessons from the Field Webinar Transcript, from the U.S. Department of Energy Technical Assistance Program (TAP).

  17. Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

    E-Print Network [OSTI]

    Mazzoni, Esteban O

    Efficient transcriptional programming promises to open new frontiers in regenerative medicine. However, mechanisms by which programming factors transform cell fate are unknown, preventing more rational selection of factors ...

  18. The Escherichia coli RhaS Transcriptional Activator: Transcriptional Activation by the DNA-Binding Domain, The Interdomain Effector Response, and Negative Autoregulation

    E-Print Network [OSTI]

    Skredenske, Jeffrey M.

    2012-05-31

    : The AraC/XylS family activator RhaS negatively 78 autoregulates rhaSR expression by preventing cyclic AMP receptor protein activation 1 CHAPTER 1 Transcription Activation by the DNA-Binding Domain of the AraC Family Protein Rha... encodes a second L-rhamnose responsive transcription activator, RhaR (37). RhaR activates transcription of the operon that encodes the two activator proteins, rhaSR (37, 38). All three operons in the L-rhamnose regulon also require a second activator...

  19. Best Possible Strategy for Finding Ground States

    SciTech Connect (OSTI)

    Franz, Astrid; Hoffmann, Karl Heinz; Salamon, Peter

    2001-06-04

    Finding the ground state of a system with a complex energy landscape is important for many physical problems including protein folding, spin glasses, chemical clusters, and neural networks. Such problems are usually solved by heuristic search methods whose efficacy is judged by empirical performance on selected examples. We present a proof that, within the large class of algorithms that simulate a random walk on the landscape, threshold accepting is the best possible strategy. In particular, it can perform better than simulated annealing and Tsallis statistics. Our proof is the first example of a provably optimal strategy in this area.

  20. Fossil Energy Word Find | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum12, 2015ExecutiveFluorescent LampFort Collins, Colorado on3of EnergyWord Find

  1. Landfill aeration worldwide: Concepts, indications and findings

    SciTech Connect (OSTI)

    Ritzkowski, M.; Stegmann, R.

    2012-07-15

    Highlights: Black-Right-Pointing-Pointer Different landfill aeration concepts and accordant application areas are described. Black-Right-Pointing-Pointer Examples of full scale projects are provided for Europe, North-America and Asia. Black-Right-Pointing-Pointer Major project findings are summarised, including prospects and limitations. Black-Right-Pointing-Pointer Inconsistencies between laboratory and full scale results have been elaborated. Black-Right-Pointing-Pointer An explanatory approach in connection with the inconsistencies is provided. - Abstract: The creation of sustainable landfills is a fundamental goal in waste management worldwide. In this connection landfill aeration contributes towards an accelerated, controlled and sustainable conversion of conventional anaerobic landfills into a biological stabilized state associated with a minimised emission potential. The technology has been successfully applied to landfills in Europe, North America and Asia, following different strategies depending on the geographical region, the specific legislation and the available financial resources. Furthermore, methodologies for the incorporation of landfill aeration into the carbon trade mechanisms have been developed in recent years. This manuscript gives an overview on existing concepts for landfill aeration; their application ranges and specifications. For all of the described concepts examples from different countries worldwide are provided, including details regarding their potentials and limitations. Some of the most important findings from these aeration projects are summarised and future research needs have been identified. It becomes apparent that there is a great demand for a systematisation of the available results and implications in order to further develop and optimise this very promising technology. The IWWG (International Waste Working Group) Task Group 'Landfill Aeration' contributes towards the achievement of this goal.

  2. The City College of New York Office of the Registrar Transcript Request Form

    E-Print Network [OSTI]

    Sun, Yi

    The City College of New York Office of the Registrar Transcript Request Form PLEASE NOTE: Fill out____ Winter____ The City College of New York Office of the Registrar Administration Building, Room A - 102 160 Convent Avenue New York, NY 10031 Attn: Transcript Request 212.650.7877 · Please allow approximately 7

  3. MUSIC TRANSCRIPTION USING AN INSTRUMENT MODEL Jun Yin, Terence Sim, Ye Wang, Arun Shenoy

    E-Print Network [OSTI]

    Wang, Ye

    MUSIC TRANSCRIPTION USING AN INSTRUMENT MODEL Jun Yin, Terence Sim, Ye Wang, Arun Shenoy National}@comp.nus.edu.sg ABSTRACT We introduce a method to transcribe music with the help of an instrument model. One of the most important and difficult problems in music transcription is polyphonic pitch estimation. Common pitch

  4. Finance Program Retention for FALL 2014 Instructions for Transcript Review Form

    E-Print Network [OSTI]

    Kostic, Milivoje M.

    Finance Program ­ Retention for FALL 2014 Instructions for Transcript Review Form College of Business at Northern Illinois University The Department of Finance Transcript Review Form should in the finance core). All NIU students are eligible to declare a major in Finance; however, students must meet

  5. APOLLO 14 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE

    E-Print Network [OSTI]

    Rathbun, Julie A.

    * * *: {( APOLLO 14 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE #12;APOLLO 14 VOICE TRANSCRIPT Pertaining to the geology of the landing site by N.G. Bailey and G.E. UI rich U.S. Geological Survey Branch of Astrogeology Flagstaff, Arizona 1975 #12;nils fOR.1 ~t.\\) IH. fl.HJ!Hl!ll( ".0

  6. APOLLO 11 .V O ICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE

    E-Print Network [OSTI]

    Rathbun, Julie A.

    * * *: {( APOLLO 11 .V O ICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE #12;APOLLO 11 VOICE TRANSCRIPT Pertaining to the geology of the landing site by N. G. Bailey and G. E. Ulrich U.S. Geological Survey Branch of Astrogeology Flagstaff, Arizona 1974 #12;USCOMM·OC 8265-P74THIS ~ORM 1\\1A) HI

  7. APOLLO 15 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE

    E-Print Network [OSTI]

    Rathbun, Julie A.

    * * *: {( APOLLO 15 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE #12;APOLLO 15 VOICE TRANSCRIPT Pertaining to the geology of the landing site ~ N.G. Bailey and G.E. Ulrich U.S. Geological Survey Branch of Astrogeology Flagstaff, Arizona 1~5 #12;BIBLIOGRAPHICDATA II. Report No. J2. 3

  8. * * * *APOLLO 12 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE

    E-Print Network [OSTI]

    Rathbun, Julie A.

    * * * *APOLLO 12 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE #12;APOLLO 12 VOICE TRANSCRIPT Pertaining to the geology of the landing site by N.G. Bailey and G.E. Ulrich U.S. Geological to the Geology of the Landing Site 7. Auchor(s) 8. Performing Organization Repr. N. G. Bailey and G. E. Ulrich No

  9. APOLLO 16 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE

    E-Print Network [OSTI]

    Rathbun, Julie A.

    * * *: {( APOLLO 16 VOICE TRANSCRIPT PERTAINING TO THE GEOLOGY OF THE LANDING SITE #12;- APOLLO 16 VOICE TRANSCRIPT Pertaining to the geology of the landIng site by N.G. Bai loey and G.E. Ulrich U.s. Geol:ogical Survey Branch of Astrogeology F]agstaff~ Arizona 1915 #12;FORM NTlS·315 UO-70

  10. TAFII250-dependent transcription of cyclin A is directed by ATF

    E-Print Network [OSTI]

    Wang, Edith

    to and activate the cyclin- dependent kinases (cdks) needed to drive cells through this proliferative cycle an intriguing link between TAF-mediated transcriptional regulation and cell cycle progression. Here we report cell cycle arrest phenotype. [Key Words: Transcription; TAFII250; cyclin A; ATF] Received June 10, 1997

  11. Finding Nonoverlapping Substructures of a Sparse Matrix

    SciTech Connect (OSTI)

    Pinar, Ali; Vassilevska, Virginia

    2005-08-11

    Many applications of scientific computing rely on computations on sparse matrices. The design of efficient implementations of sparse matrix kernels is crucial for the overall efficiency of these applications. Due to the high compute-to-memory ratio and irregular memory access patterns, the performance of sparse matrix kernels is often far away from the peak performance on a modern processor. Alternative data structures have been proposed, which split the original matrix A into A{sub d} and A{sub s}, so that A{sub d} contains all dense blocks of a specified size in the matrix, and A{sub s} contains the remaining entries. This enables the use of dense matrix kernels on the entries of A{sub d} producing better memory performance. In this work, we study the problem of finding a maximum number of nonoverlapping dense blocks in a sparse matrix, which is previously not studied in the sparse matrix community. We show that the maximum nonoverlapping dense blocks problem is NP-complete by using a reduction from the maximum independent set problem on cubic planar graphs. We also propose a 2/3-approximation algorithm that runs in linear time in the number of nonzeros in the matrix. This extended abstract focuses on our results for 2x2 dense blocks. However we show that our results can be generalized to arbitrary sized dense blocks, and many other oriented substructures, which can be exploited to improve the memory performance of sparse matrix operations.

  12. Genome-wide analysis of transcriptional expression programs, regulatory networks and Cis-regulatory sequences in Saccharomyces cerevisiae

    E-Print Network [OSTI]

    Harbison, Christopher T., 1973-

    2005-01-01

    Historically, knowledge of gene-specific transcription has been accumulated by the study of the individual genetic and physical interactions between transcriptional regulators and the genes they regulate, often requiring ...

  13. Transcripts are an official, complete and unabridged listing of a student's educational record at the University of Saskatchewan as of the day the transcript is produced. It is the student's responsibility to ensure that their record is complete to their

    E-Print Network [OSTI]

    Saskatchewan, University of

    are an alumni and do not know your NSID and/or password, contact University Advancement at 306-966-5186 or 1 Building. Please Note: Photo identification is required to pick up transcripts TranscriptRequestForm Over or delivered to the student. The envelope containing the transcript is then affixed with a seal across the flap

  14. Environmental Scientists Find Antibiotics, Bacteria, Resistance Genes in Feedlot Dust

    E-Print Network [OSTI]

    Rock, Chris

    Environmental Scientists Find Antibiotics, Bacteria, Resistance Genes in Feedlot Dust :: Texas Tech Today http://today.ttu.edu/2015/01/environmental-scientists-find-antibiotics Print Email + Font - Font Environmental Scientists Find Antibiotics, Bacteria, Resistance Genes

  15. District-school leadership for organizational learning : finding the balance

    E-Print Network [OSTI]

    Umekubo, Lisa Ann

    2012-01-01

    Learning: Finding the Balance Lisa A. Umekubo, a researcher/Learning: Finding the Balance CVESD has made an impact byLearning: Finding the Balance CVESD has made an impact by

  16. The developmental expression dynamics of Drosophila melanogaster transcription factors

    E-Print Network [OSTI]

    Adryan, Boris; Teichmann, Sarah A

    2010-04-12

    -specific activation and repression of genes. The expression of TFs should therefore reflect the core expression program of each cell. Results We studied the expression dynamics of about 750 TFs using the available genomics resources in Drosophila melanogaster. We find...

  17. What is VuFind? VuFind is a newer inter-

    E-Print Network [OSTI]

    Lee, Tonghun

    to narrow by color, price, etc. #12;Basic Searching: 1. Enter search term(s) in box, use " " to searchFind is now the default catalog for the University of Illinois, you can still search the Classic Catalog. Certain types of searches need to be done in the Classic Catalog; they are listed to the right. Vu

  18. ULTRA-DEEP WATER ADVISORY COMMITTEE FINDINGS AND

    Energy Savers [EERE]

    ULTRA-DEEP WATER ADVISORY COMMITTEE FINDINGS AND RECOMMENDATIONS 2014 ULTRA-DEEPWATER ADVISORY COMMITTEE COMMITTEE FINDINGS AND RECOMMENDATIONS i Table of Contents Research and...

  19. Study Finds 54 Gigawatts of Offshore Wind Capacity Technically...

    Energy Savers [EERE]

    Study Finds 54 Gigawatts of Offshore Wind Capacity Technically Possible by 2030 Study Finds 54 Gigawatts of Offshore Wind Capacity Technically Possible by 2030 September 11, 2014 -...

  20. Innovative Financing Solutions: Finding Money for Your Energy...

    Broader source: Energy.gov (indexed) [DOE]

    to find funding for your energy efficiency projects focusing on l-p agreements. Author: Energy Star Innovative Financing Solutions: Finding Money for Your Energy Efficiency...

  1. Jefferson Lab finds its man Mont (Inside Business) | Jefferson...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    https:www.jlab.orgnewsarticlesjefferson-lab-finds-its-man-mont-inside-business Jefferson Lab finds its man Mont Hugh Montgomery Hugh Montgomery, a British nuclear physicist...

  2. Regulation of lipogenic gene transcription during fasting and feeding/insulin: Role of USF, SREBP-1c, and BAF60c

    E-Print Network [OSTI]

    Wong, Roger Hoi Fung

    2010-01-01

    Gene Transcription during Fasting and Feeding/insulin: RoleGene Transcription during Fasting and Feeding/insulin: Roleproteins during the fasting/feeding transition. First, USF

  3. Sox9andNFIACoordinateaTranscriptionalRegulatory Cascade during the Initiation of Gliogenesis

    E-Print Network [OSTI]

    Gronostajski, Richard M.

    Deneen1,3,* 1Center for Cell and Gene Therapy 2Department of Molecular and Human Genetics 3Department). These sequential differentiative steps are governed by temporal changes in the transcription factor milieu

  4. Experimental Incubations Elicit Profound Changes in Community Transcription in OMZ Bacterioplankton

    E-Print Network [OSTI]

    Stewart, Frank J.

    Sequencing of microbial community RNA (metatranscriptome) is a useful approach for assessing gene expression in microorganisms from the natural environment. This method has revealed transcriptional patterns in situ, but ...

  5. The Role of Specificity Protein Transcription Factors And Noncoding Rnas In Colorectal And Hepatocellular Carcinomas 

    E-Print Network [OSTI]

    Gandhy, Shruti

    2013-05-01

    Specificity protein transcription factors, Spl, Sp3 and Sp4 are overexpressed in multiple cancer cell lines and tumor types and Sp-regulated genes play an important role in cancer cell proliferation, survival, angiogenesis ...

  6. FapR, a Bacterial Transcription Factor Involved in Global Regulation of Membrane Lipid Biosynthesis

    E-Print Network [OSTI]

    Schujman, Gustavo E

    Bacterial cells exert exquisite control over the biosynthesis of their membrane lipids, but the mechanisms are obscure. We describe the identification and purification from Bacillus subtilis of a transcription factor, FapR, ...

  7. Genomic neighbourhood and the regulation of gene expression Genomic neighbourhood and transcriptional regulation

    E-Print Network [OSTI]

    Babu, M. Madan

    Genomic neighbourhood and the regulation of gene expression Genomic neighbourhood and transcriptional regulation Subhajyoti De and M. Madan Babu MRC Laboratory of Molecular Biology, Hills Road..................................................................................................................................................................................1 2. Genomic neighbourhood and its influence on gene regulation

  8. Mechanisms of transcriptional activation of estrogen responsive genes in breast cancer cells 

    E-Print Network [OSTI]

    Chen, Chien-Cheng

    2009-06-02

    Estrogen receptor (ER) acts as a ligand-activated transcription factor that regulates the expression of genes. The genomic mechanisms of ER action include ligand-induced dimerization of ER which binds estrogen responsive ...

  9. Transcript of March 28, 2013, TAP webinar titled Internal Benchmarking Outreach and Data Collection Techniques

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy (DOE) Technical Assistance Program (TAP) transcript of a TAP webinar held on March 28, 2013 and dealing with internal benchmarking outreach and data collection techniques.

  10. Evolution of transcription factors and the gene regulatory network in Escherichia coli

    E-Print Network [OSTI]

    Babu, M. Madan

    Evolution of transcription factors and the gene regulatory network in Escherichia coli M. Madan Escherichia coli. In order to gain insight into the evolution of the E.coli regula- tory network, we analysed

  11. Characterizing the function of transcription factor 15 (Tcf15) in pluripotent cells 

    E-Print Network [OSTI]

    Lin, Chia-Yi

    2015-06-29

    Pluripotent embryonic stem (ES) cells are heterogeneous mixtures of naïve and lineage-primed states defined by distinct transcription factor expression profiles. However, the events that prime pluripotent cells ...

  12. Analysis of variation at transcription factor binding sites in Drosophila and humans

    E-Print Network [OSTI]

    Spivakov, Mikhail

    Background: Advances in sequencing technology have boosted population genomics and made it possible to map the positions of transcription factor binding sites (TFBSs) with high precision. Here we investigate TFBS variability ...

  13. Transcript of April 11, 2013, TAP webinar titled Financing Energy Upgrades for K-12 School Districts

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy (DOE) Technical Assistance Program (TAP) transcript of a TAP webinar held on April 11, 2013 and dealing with how to finance energy efficiency upgrades for K-12 school districts.

  14. SciP : a novel inhibitor of CtrA transcriptional activity in Caulobacter crescentus

    E-Print Network [OSTI]

    Gora, Kasia G. (Kasia Gabriela)

    2011-01-01

    Cells must sense changes in their environment and respond appropriately in order to survive. A common survival strategy is for cells to translate an environmental signal into the activity of a transcription factor they ...

  15. 'I Saw You Disappear with My Own Eyes': Hidden Transcripts of New York Black Isrealite Bricolage

    E-Print Network [OSTI]

    Dorman, Jacob S.

    2007-08-01

    To date, scholars have tended to view Black Israelites as mercenary, derivative, or imitative. However, this microhistorical reading of the public, partial, and hidden transcripts of New York Rabbi Wentworth Arthur Matthew's ...

  16. Refinement of light-responsive transcript lists using rice oligonucleotide arrays: evaluation of gene-redundancy.

    E-Print Network [OSTI]

    2008-01-01

    Refinement of Light-Responsive Transcript Lists Using Riceleaves of two-week old plants grown in a natural light-darkcycle (light-grown) in comparison to RNA from October 2008 |

  17. Modular design of coiled coils to target bZIP transcription factors

    E-Print Network [OSTI]

    Kaplan, Jenifer (Jenifer Brooke)

    2014-01-01

    Basic leucine-zipper (bZIP) transcription factors regulate many important cellular processes including tissue differentiation, stress responses and the unfolded protein response, the cell cycle, and apoptosis. Understanding ...

  18. Transcriptional analysis of the healing response of wounded nerves treated with collagen and silicone tubes

    E-Print Network [OSTI]

    Wong, Matthew Q

    2008-01-01

    This study examines the transcriptional differences between nerve wounds treated with silicone tubes and those treated with collagen nerve regeneration templates. The primary motivation for the study is to test the hypothesis ...

  19. Adaptable functionality of transcriptional feedback in bacterial two-component systems

    E-Print Network [OSTI]

    Ray, J. Christian J.; Igoshin, Oleg A.

    2010-02-12

    A widespread mechanism of bacterial signaling occurs through two-component systems, comprised of a sensor histidine kinase (SHK) and a transcriptional response regulator (RR). The SHK activates RR by phosphorylation. The ...

  20. Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-? Signaling

    E-Print Network [OSTI]

    Mullen, Alan C.

    Transforming growth factor beta (TGF-?) signaling, mediated through the transcription factors Smad2 and Smad3 (Smad2/3), directs different responses in different cell types. Here we report that Smad3 co-occupies the genome ...

  1. Prosodic transcription of glasgow english: an evaluation study of GlaToBI 

    E-Print Network [OSTI]

    Mayo, Catherine; Aylett, Matthew; Ladd, Robert

    1997-01-01

    GlaToBI, a version of the ToBI prosodic transcription system which can be used to transcribe the intonation patterns of western Scottish (Glasgow) English, is currently under development. An assessment of GlaToBI, similar ...

  2. POLYPHONIC PIANO TRANSCRIPTION USING NON-NEGATIVE MATRIX FACTORISATION WITH GROUP SPARSITY

    E-Print Network [OSTI]

    Plumbley, Mark

    POLYPHONIC PIANO TRANSCRIPTION USING NON-NEGATIVE MATRIX FACTORISATION WITH GROUP SPARSITY Ken O'Hanlon and Mark D. Plumbley Queen Mary University of London ABSTRACT Non-negative Matrix Factorisation (NMF

  3. The interaction of nucleocapsid protein, a reverse transcription accessory factor, with replication primer transfer RNA 

    E-Print Network [OSTI]

    Chang, Hsueh-O

    1994-01-01

    In the initiation of reverse transcription in animal retroviruses, an obligate step is the formation of RNA duplex between the transfer RNA primer and a complementary genomic RNA sequence, termed the primer binding site (PBS). A virally encoded...

  4. The LIMSI Broadcast News Transcription System Jean-Luc Gauvain, Lori Lamel, Gilles Adda

    E-Print Network [OSTI]

    the last few years directed at the transcription of broadcast news data. We describe our development work des kontinuierlichenStroms von inhomogenen Daten sind zwei grundlegende Probleme zu l¨osen. Diese

  5. Transcriptional regulation of seed-specific gene expression - from PvALF/ ABI3 to phaseolin 

    E-Print Network [OSTI]

    Ng, Wang Kit

    2006-10-30

    The phaseolin (phas) promoter drives the copious production of transcripts encoding the protein phaseolin during seed embryogenesis but is silent in vegetative tissues when a nucleosome is positioned over its three phased ...

  6. VISUAL ANALYSIS FOR DRUM SEQUENCE TRANSCRIPTION Kevin McGuinness

    E-Print Network [OSTI]

    Richard, Gaël

    'Connor , Ga¨el Richard Centre for Digital Video Processing, Dublin City University, Glasnevin, Dublin 9-based mu- sic retrieval systems, but also finds application in computer-aided music teaching or composition as a classification problem thus removing the need for training sequence-dependent classifiers. Furthermore, even

  7. The Space-Weather Awareness Dialogue: Findings and Outlook

    E-Print Network [OSTI]

    Schrijver, Karel

    The Space-Weather Awareness Dialogue: Findings and Outlook An event hosted by the European-WEATHER AWARENESS DIALOGUE: FINDINGS AND OUTLOOK An event hosted by the European Commission's Joint Research Centre

  8. Got a Minute? Which Higgs did we find?

    SciTech Connect (OSTI)

    Stupak, John

    2014-06-26

    Dr. John Stupak talks about the discovery of the Higgs boson. Did scientists find the Higgs boson predicted back in 1964 or did they find just one of a group of particles, with the others still to be found?

  9. Got a Minute? Which Higgs did we find?

    ScienceCinema (OSTI)

    Stupak, John

    2014-09-15

    Dr. John Stupak talks about the discovery of the Higgs boson. Did scientists find the Higgs boson predicted back in 1964 or did they find just one of a group of particles, with the others still to be found?

  10. EERE 2014 Wind Technologies Market Report Finds Wind Power at...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2014 Wind Technologies Market Report Finds Wind Power at Record Low Prices EERE 2014 Wind Technologies Market Report Finds Wind Power at Record Low Prices August 10, 2015 - 11:00am...

  11. Local algorithms for graph partitioning and finding dense subgraphs

    E-Print Network [OSTI]

    Andersen, Reid

    2007-01-01

    ed local partitioning algorithm . . . . . . . . . . . .7 A Local Algorithm for Finding DenseComparison of local partitioning algorithms . . . . . . . .

  12. Report of Findings COE Staff Development Training Day 2014

    E-Print Network [OSTI]

    Frantz, Kyle J.

    by the COE. Findings displayed for each item using a pie chart with proportions included. #12;Executive

  13. Regulating expression of cell and tissue-specific genes by modifying transcription

    SciTech Connect (OSTI)

    Beachy, Roger N; Dai, Shunhong

    2010-06-14

    Transcriptional regulation is the primary step to control gene expression, therefore function. Such regulation is achieved primarily via a combination of the activities of the promoter cis regulatory DNA elements and trans regulatory proteins that function through binding to these DNA elements. Rice bZIP transcription factors RF2a, RF2b and RLP1 play key roles in regulating the activity of a vascular tissue specific promoter isolated from Rice Tungro Bacilliform Virus (RTBV), through their interactions with the Box II essential cis element located in the promoter (Dai et al., 2006., Dai et al., 2004., Yin et al., 1997). RF2a, RF2b and RLP1 possess multiple regulatory domains. Functional characterization reveals that those domains can activate or repress the activity of the RTBV promoter. It is equally as important to recognize that these proteins control plant development by regulating differentiation and/or function of the vascular tissues. Studies of transcriptional regulation of the RTBV promoter by this group of bZIP proteins will not only provide insights about gene expression in the vascular tissue, but also insights about general mechanisms of transcription activation and repression. The knowledge gained from this research will also enable us to develop a well-described set of tools that can be used to control expression of multiple genes in transgenic plants. We have proposed characterize the function domains of RF2a, RF2b and RLP1 and explore the biological function of the transcription repressor RLP1.

  14. Transcriptional regulation of human RANK ligand gene expression by E2F1

    SciTech Connect (OSTI)

    Hu Yan [Department of Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263 (United States); Sun Meng [Department of Urology and Cancer Center, University of California at Davis, School of Medicine, 4860 Y Street, Suite 3500, Sacramento, CA 95817 (United States); Graduate Program of Pharmacology and Toxicology, University of California at Davis, Sacramento, CA 95817 (United States); Nadiminty, Nagalakshmi; Lou Wei [Department of Urology and Cancer Center, University of California at Davis, School of Medicine, 4860 Y Street, Suite 3500, Sacramento, CA 95817 (United States); Pinder, Elaine [Department of Urology and Cancer Center, University of California at Davis, School of Medicine, 4860 Y Street, Suite 3500, Sacramento, CA 95817 (United States); Graduate Program of Pharmacology and Toxicology, University of California at Davis, Sacramento, CA 95817 (United States); Gao, Allen C. [Department of Urology and Cancer Center, University of California at Davis, School of Medicine, 4860 Y Street, Suite 3500, Sacramento, CA 95817 (United States); Graduate Program of Pharmacology and Toxicology, University of California at Davis, Sacramento, CA 95817 (United States)], E-mail: acgao@ucdavis.edu

    2008-06-06

    Receptor activator of nuclear factor kappa B ligand (RANKL) is a critical osteoclastogenic factor involved in the regulation of bone resorption, immune function, the development of mammary gland and cardiovascular system. To understand the transcriptional regulation of RANKL, we amplified and characterized a 1890 bp 5'-flanking sequence of human RANKL gene (-1782 bp to +108 bp relative to the transcription start site). Using a series of deletion mutations of the 1890 bp RANKL promoter, we identified a 72 bp region (-172 to -100 bp) mediating RANKL basal transcriptional activity. Sequence analysis revealed a putative E2F binding site within this 72 bp region in the human RANKL promoter. Overexpression of E2F1 increased RANKL promoter activity, while down-regulation of E2F1 expression by small interfering RNA decreased RANKL promoter activity. RT-PCR and enzyme linked immunosorbent assays (ELISA) further demonstrated that E2F1 induced the expression of RANKL. Electrophoretic gel mobility shift assays (EMSA) and antibody competition assays confirmed that E2F1 proteins bind to the consensus E2F binding site in the RANKL promoter. Mutation of the E2F consensus binding site in the RANKL promoter profoundly reduced the basal promoter activity and abolished the transcriptional modulation of RANKL by E2F1. These results suggest that E2F1 plays an important role in regulating RANKL transcription through binding to the E2F consensus binding site.

  15. How the DNA sequence affects the Hill curve of transcriptional response

    E-Print Network [OSTI]

    M. Sheinman; Y. Kafri

    2011-11-16

    The Hill coefficient is often used as a direct measure of the cooperativity of binding processes. It is an essential tool for probing properties of reactions in many biochemical systems. Here we analyze existing experimental data and demonstrate that the Hill coefficient characterizing the binding of transcription factors to their cognate sites can in fact be larger than one -- the standard indication of cooperativity -- even in the absence of any standard cooperative binding mechanism. By studying the problem analytically, we demonstrate that this effect occurs due to the disordered binding energy of the transcription factor to the DNA molecule and the steric interactions between the different copies of the transcription factor. We show that the enhanced Hill coefficient implies a significant reduction in the number of copies of the transcription factors which is needed to occupy a cognate site and, in many cases, can explain existing estimates for numbers of the transcription factors in cells. The mechanism is general and should be applicable to other biological recognition processes.

  16. Stochasticity and traffic jams in the transcription of ribosomal RNA: Intriguing role of termination and antitermination

    E-Print Network [OSTI]

    Stefan Klumpp; Terence Hwa

    2008-11-19

    In fast growing bacteria, ribosomal RNA (rRNA) is required to be transcribed at very high rates to sustain the high cellular demand on ribosome synthesis. This results in dense traffic of RNA polymerases (RNAP). We developed a stochastic model, integrating results of single-molecule and quantitative in vivo studies of E. coli, to evaluate the quantitative effect of pausing, termination, and antitermination on rRNA transcription. Our calculations reveal that in dense RNAP traffic, spontaneous pausing of RNAP can lead to severe "traffic jams", as manifested in the broad distribution of inter-RNAP distances and can be a major factor limiting transcription and hence growth. Our results suggest the suppression of these pauses by the ribosomal antitermination complex to be essential at fast growth. Moreover, unsuppressed pausing by even a few non-antiterminated RNAPs can already reduce transcription drastically under dense traffic. However, the termination factor Rho can remove the non-antiterminated RNAPs and restore fast transcription. The results thus suggest an intriguing role by Rho to enhance rather than attenuate rRNA transcription.

  17. Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13

    SciTech Connect (OSTI)

    Warren, G. [Yale Univ., New Haven, CT (United States)] [Yale Univ., New Haven, CT (United States); Gordon, M.; Siracusa, L.D. [Jefferson Cancer Institute, Philadelphia, PA (United States)] [and others] [Jefferson Cancer Institute, Philadelphia, PA (United States); and others

    1996-01-15

    Transcription factors are a major determinant of developmental fate. The chromosomal localization of the genes encoding these proteins provides important information that can link them to known genetic abnormalities. Here, we report the mapping of the mouse gene for transcription factor AP-2, a protein that has been implicated in human oncogenesis. Using FISH, we have mapped the gene encoding the transcription factor AP-2, Tcfap2, to mouse Chromosome 13A5-B1. We have also extended this analysis by placing Tcfap2 on the mouse mutations that map in the vicinity of this transcription factor. 25 refs., 2 figs., 1 tab.

  18. EA-1720: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding0: Finding

  19. EA-1829: Final Environmental Assessment and Finding of No Significant...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EA-1829: Final Environmental Assessment and Finding of No Significant Impact Phycal Algae Pilot Project, Wahiawa and Kalaeloa, HI (November 2011) For more information, contact:...

  20. Finding of No Significant Impact, Federal Register, 73 FR 2017...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    73 FR 2017, January 11, 2008 Document details the finding of no significant impact of the Energy-Efficient Performance Requirements for New Federal Commercial and Residential...

  1. Webinar: Wind-to-Hydrogen Cost Modeling and Project Findings

    Office of Energy Efficiency and Renewable Energy (EERE)

    Video recording and text version of the webinar titled, Wind-to-Hydrogen Cost Modeling and Project Findings, originally presented on January 17, 2013.

  2. EA-1876: Final Environmental Assessment and Finding of No Significant...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Finding of No Significant Impact Pennsylvania State Energy Program's Conergy Navy Yard Solar Project EA-1876-FEA-2011.pdf More Documents & Publications Microsoft Word -...

  3. Neutrons find "missing" magnetism of plutonium | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Los Alamos National Laboratory 505-667-0471 Neutrons find "missing" magnetism of plutonium Doug Abernathy, left, ARCS instrument scientist at Oak Ridge National Laboratory,...

  4. *** CANCELED *** SCIENCE ON SATURDAY- "Finding a Needle in A...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ON SATURDAY- "Finding a Needle in A (Genomic) Haystack or How Can Computers Help Cure Cancer" Professor Olga G. Troyanskaya Lewis-Sigler Institute for Integrative Genomics &...

  5. EA-1396: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Significant Impact EA-1396: Finding of No Significant Impact Small-Scale Geothermal Power Plant and Direct-Use Geothermal Application at Americulture, Inc., Cotton City, New...

  6. Find Energy Incentives Quicker and Easier with DSIRE Open Data...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Website March 3, 2015 - 4:16pm Addthis The updated Database of State Incentives for Renewables & Efficiency helps homeowners and businesses find incentive programs that can reduce...

  7. Study finds radioactivity around Los Alamos largely due to natural...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radioactivity largely due to natural sources Study finds radioactivity around Los Alamos largely due to natural sources The study was subsequently peer reviewed externally by...

  8. EA-1640: Final Environmental Assessment and Finding of No Significant...

    Energy Savers [EERE]

    and Finding of No Significant Impact Transfer of Land and Facilities within the East Tennessee Technology Park and Surrounding Area, Oak Ridge, Tennessee DOE proposes to...

  9. Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis

    SciTech Connect (OSTI)

    Neff, Michael M.

    2011-06-23

    This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled “Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis”. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

  10. Uncorrected Proof Copy Finding Genes by Using Computational Tools 85

    E-Print Network [OSTI]

    Uncorrected Proof Copy Finding Genes by Using Computational Tools 85 Job: Plant Functional Genomics/Rev.02.03 Uncorrected Proof Copy #12;Uncorrected Proof Copy Finding Genes by Using Computational Tools 87 Computational Tools 89 Job: Plant Functional Genomics--Grotewold Compositor: Nettype Chapter: Chapter 6 Date: 3

  11. The Automation of Sound Reasoning and Successful Proof Finding

    E-Print Network [OSTI]

    Fitelson, Branden

    709 44 The Automation of Sound Reasoning and Successful Proof Finding LARRY WOS AND BRANDEN scientist naturally envisioned the automation of sound rea- soning ­ reasoning in which conclusions, and find proofs. But can such logical reasoning be fully automated? Can a single computer program

  12. Millersvilie Find this handbook electronically on the Biology

    E-Print Network [OSTI]

    Hardy, Christopher R.

    BIOLOGY STUDENT HANDBOOK 2014-2015 Millersvilie University Find this handbook electronically on the Biology homepage (www.millersville.edu/biology/) under "Quick Links". #12;Welcome! Welcome this Biology Student Handbook. We hope that you will find this handbook useful throughout your career

  13. Effectively Finding Relevant Web Pages from Linkage Information

    E-Print Network [OSTI]

    Cortes, Corinna

    Effectively Finding Relevant Web Pages from Linkage Information Jingyu Hou and Yanchun Zhang to find relevant pages for a given Web page (URL). The first algorithm comes from the extended cocitation analysis of the Web pages. It is intuitive and easy to implement. The second one takes advantage of linear

  14. Finding Glass Kenton McHenry, Jean Ponce

    E-Print Network [OSTI]

    Forsyth, David

    Finding Glass Kenton McHenry, Jean Ponce Beckman Institute University of Illinois Urbana, IL 61801. This paper addresses the problem of finding glass ob- jects in images. Visual cues obtained by combining with the strong highlights typical of glass surfaces are used to train a hierarchy of classifiers, identify glass

  15. Efficiently finding optimal winding-constrained loops in the plane

    E-Print Network [OSTI]

    Vernaza, Paul

    Efficiently finding optimal winding- constrained loops in the plane Paul Vernaza, Venkatraman winding- constrained loops in the plane that are optimal with respect to a minimum-cost objective times it winds around each obstacle, enabling us to reduce the problem of finding paths satisfying

  16. Using Process Data for Finding Self-optimizing Controlled Variables

    E-Print Network [OSTI]

    Skogestad, Sigurd

    Using Process Data for Finding Self-optimizing Controlled Variables Johannes J¨aschke and Sigurd the process gain. It does not require a model which is optimized off-line to find the controlled variable. Keywords: Process Optimization, Control, Partial least squares, Empirical modelling, Self-optimizing

  17. Reduction of DNA contamination in RNA samples for reverse transcription-polymerase chain reaction using selective precipitation by compaction agents.

    E-Print Network [OSTI]

    Fox, George

    Reduction of DNA contamination in RNA samples for reverse transcription-polymerase chain reaction by reverse transcription-polymerase chain reaction (RT-PCR) is DNA contamination, which can produce artifactually increased mRNA concentration. Current methods to eliminate contaminating DNA can compromise

  18. Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes

    E-Print Network [OSTI]

    Murata, Kazutaka; Kouzarides, Tony; Bannister, Andrew J.; Gurdon, John

    2010-02-04

    reprogramming. Results Reverse transcription polymerase chain reaction analysis shows that the transcriptional reprogramming of pluripotency genes, such as Sox2 and Oct4, takes place in transplanted nuclei from C3H10T1/2 cells and from newly differentiated mouse...

  19. Role of a Transcriptional Regulator in Programmed Cell Death and Plant Development

    SciTech Connect (OSTI)

    Julie M. Stone

    2008-09-13

    The long-term goal of this research is to understand the role(s) and molecular mechanisms of programmed cell death (PCD) in the controlling plant growth, development and responses to biotic and abiotic stress. We developed a genetic selection scheme to identify A. thaliana FB1-resistant (fbr) mutants as a way to find genes involved in PCD (Stone et al., 2000; Stone et al., 2005; Khan and Stone, 2008). The disrupted gene in fbr6 (AtSPL14) responsible for the FB1-insensitivity and plant architecture phenotypes encodes a plant-specific SBP DNA-binding domain transcriptional regulator (Stone et al., 2005; Liang et al., 2008). This research plan is designed to fill gaps in the knowledge about the role of SPL14 in plant growth and development. The work is being guided by three objectives aimed at determining the pathways in which SPL14 functions to modulate PCD and/or plant development: (1) determine how SPL14 functions in plant development, (2) identify target genes that are directly regulated by SPL14, and (3) identify SPL14 modifications and interacting proteins. We made significant progress during the funding period. Briefly, some major accomplishments are highlighted below: (1) To identify potential AtSPL14 target genes, we identified a consensus DNA binding site for the AtSPL14 SBP DNA-binding domain using systematic evolution of ligands by exponential selection (SELEX) and site-directed mutagenesis (Liang et al., 2008). This consensus binding site was used to analyze Affymetrix microarray gene expression data obtained from wild-type and fbr6 mutant plants to find possible AtSPL14-regulated genes. These candidate AtSPL14-regulated genes are providing new information on the molecular mechanisms linking plant PCD and plant development through modulation of the 26S proteasome. (2) Transgenic plants expressing epitope-tagged versions of AtSPL14 are being used to confirm the AtSPL14 targets (by ChIP-PCR) and further dissect the molecular interactions (Nazarenus, Liang and Stone, in preparation) (3) Double mutants generated between fbr6 and various accelerated cell death (acd) mutants indicate that sphingolipid metabolism is influenced by AtSPL14 and sphingolipidomics profiling supports this conclusion (Lin, Markham and Stone, in preparation). (4) A new set of phenotypes have been uncovered in the original fbr6-1 mutant, including a short-root phenotype related to auxin signaling and altered photosynthetic parameters related to stomatal density and conductance (Lin and Stone, in preparation; Lin, Madhavan and Stone, in preparation). Additional AtSPL14-related mutants and transgenic plants have been generated to effectively dissect the functions of AtSPL14, including a dominant negative fbr6-2 allele and transgenic plants overexpressing FBR6/AtSPL14 that display an accelerated cell death (acd) phenotype.

  20. Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum

    E-Print Network [OSTI]

    Arnold, Jonathan

    Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum Richard M.R. Coulson,1,3 Neil Hall,2 and Christos A. Ouzounis1 1 Computational Genomics Group10 1SD, United Kingdom; 2 The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus

  1. The Transcription Factor WIN1/SHN1 Regulates Cutin Biosynthesis in Arabidopsis thaliana W

    E-Print Network [OSTI]

    Pauly, Markus

    influence on its ability to protect the plant against various forms of biotic and abiotic stress. WAX INDUCER1 (WIN1) and related transcription factors have recently been shown to trigger wax production of genes associated with wax biosynthesis, suggesting that the regulation of cutin and wax production

  2. USING DNASE DIGESTION DATA TO ACCURATELY IDENTIFY TRANSCRIPTION FACTOR BINDING SITES

    E-Print Network [OSTI]

    Hartemink, Alexander

    USING DNASE DIGESTION DATA TO ACCURATELY IDENTIFY TRANSCRIPTION FACTOR BINDING SITES KAIXUAN LUO1. But methods combining DNase digestion data with TF binding specificity information could potentially be used on the genomic digestion prod- ucts of deoxyribonuclease I (DNase I, which we will simply call DNase) might

  3. Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells

    E-Print Network [OSTI]

    Babu, M. Madan

    Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells Daniel Hebenstreit1 , Andrew Deonarine1 , M Madan Babu and Sarah A Teichmann CD4+ T cells play key roles in orchestrating adaptive immune responses, and are a popular model for mammalian cell differentiation. While immune

  4. The Turkey Transcription Factor Pit-1/GHF-1 Can Activate the Turkey Prolactin and Growth Hormone

    E-Print Network [OSTI]

    Ramachandran, Ramesh

    The Turkey Transcription Factor Pit-1/GHF-1 Can Activate the Turkey Prolactin and Growth Hormone by cotransfection assays and immunofluorescence staining of pituitary sec- tions. In cotransfection assays, turkey Pit-1 activated the turkey Prl, turkey GH, and rat Prl promoters 3.8-, 3.7-, and 12.5-fold

  5. Integrated Analysis of Metabolite and Transcript Levels Reveals the Metabolic Shifts That Underlie Tomato Fruit

    E-Print Network [OSTI]

    Pauly, Markus

    in the abundance of metabolites of both primary and secondary metabolism during development. The metabolite changesIntegrated Analysis of Metabolite and Transcript Levels Reveals the Metabolic Shifts That Underlie Nacional de Tecnologi´a Agri´cola Argentina, Buenos Aires, Argentina (F.C.); and Department of Plant

  6. CARRIE web service: automated transcriptional regulatory network inference and interactive analysis

    E-Print Network [OSTI]

    Weng, Zhiping

    CARRIE web service: automated transcriptional regulatory network inference and interactive analysis; Accepted March 26, 2004 ABSTRACT We present an intuitive and interactive web service for CARRIE in the cellular response. The CARRIE web service is freely available at http://zlab.bu.edu/ CARRIE-web

  7. Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4

    E-Print Network [OSTI]

    Dinner, Aaron

    Immunity Article Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical factor IRF4 regulates immuno- globulin class switch recombination and plasma cell differentiation. Its differing concentrations appear to regulate mutually antagonistic programs of B and plasma cell gene

  8. Laser zona drilling does not induce hsp70i transcription in blastomeres of eight-cell

    E-Print Network [OSTI]

    Wangh, Lawrence J.

    Laser zona drilling does not induce hsp70i transcription in blastomeres of eight-cell mouse embryos To assess whether zona drilling with a 1,480-nm laser induces heat shock in eight-cell embryos, we measured that had or had not been heated at 43°C. Unlike heating, laser zona drilling did not stimulate hsp70i

  9. BIOLOGY CONTRIBUTION TRANSIENT GENOME-WIDE TRANSCRIPTIONAL RESPONSE TO LOW-DOSE

    E-Print Network [OSTI]

    Rocke, David M.

    BIOLOGY CONTRIBUTION TRANSIENT GENOME-WIDE TRANSCRIPTIONAL RESPONSE TO LOW-DOSE IONIZING RADIATION of low-dose low linear energy transfer ionizing radiation on healthy human skin are largely unknown- ples, which returned to baseline by 24 hours postexposure. Conclusions: Low doses of ionizing radiation

  10. Automated genomic context analysis and experimental validation platform for discovery of prokaryote transcriptional regulator functions

    SciTech Connect (OSTI)

    Martí-Arbona, Ricardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mu, Fangping [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Nowak-Lovato, Kristy L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wren, Melinda S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Unkefer, Clifford J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Unkefer, Pat J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-12-18

    The clustering of genes in a pathway and the co-location of functionally related genes is widely recognized in prokaryotes. We used these characteristics to predict the metabolic involvement for a Transcriptional Regulator (TR) of unknown function, identified and confirmed its biological activity.

  11. Transcription Journal Club -2013-2014 September 3 Tuesday 1PM Magda Potok Journal Club

    E-Print Network [OSTI]

    Capecchi, Mario R.

    Transcription Journal Club - 2013-2014 September 3 Tuesday 1PM Magda Potok Journal Club September 10 Tuesday 5PM Stephanie Cuhna Research Talk September 17 Tuesday 1PM Yixuan Guo Journal Club Talk October 08 Tuesday 1PM Chongil Yi Journal Club October 15 Tuesday 5PM Christopher Gregg Postdoc

  12. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex 

    E-Print Network [OSTI]

    Ng, Huck-Hui; Zhang, Yi; Hendrich, Brian; Johnson, Colin A; Turner, Bryan M; Erdjument-Bromage, Hediye; Tempst, Paul; Reinberg, Danny; Bird, Adrian P

    Mammalian DNA is methylated at many CpG dinucleotides. The biological consequences of methylation are mediated by a family of methyl-CpG binding proteins (1–4). The best characterized family member is MeCP2, a transcriptional ...

  13. Sequence elements within an HSP70 promoter counteract transcriptional transgene silencing in Chlamydomonas

    E-Print Network [OSTI]

    gene silencing (TGS), which is characterized by a block in transgene transcription, and post become propagated within the entire organism, resulting in systemic transgene silencing. TGS- TGS may originate from the transgene itself, i.e. from arrays of repeated transgene copies (Furner

  14. Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1

    E-Print Network [OSTI]

    Halazonetis, Thanos

    University, Nagoya, Japan Introduction Transcriptional gene silencing (TGS) refers to the stable repression suppress the expression of certain protein-coding genes. In multicellular eukaryotes, TGS can persist for plants. Such TGS stability is achieved by the concerted action of multiple epigenetic mechanisms

  15. Genomic analysis shows a tight link between transcription factor dynamics and regulatory

    E-Print Network [OSTI]

    Babu, M. Madan

    of all regulatory interactions between TFs and their target genes (TGs) in a cell can be represented as a transcription regulatory network in which nodes represent TFs and TGs, and directed edges represent the regulation of TGs by TFs. This representation provides a powerful framework to uncover the general

  16. A central integrator of transcription networks in plant stress and energy signalling

    E-Print Network [OSTI]

    Sheen, Jen

    LETTERS A central integrator of transcription networks in plant stress and energy signalling Elena are the principal solar energy converter sustaining life on Earth. Despite its fundamental importance, little to globally regulate plant metabolism, energy balance, growth and survival. In con- trast to the prevailing

  17. A suite of web-based programs to search for transcriptional regulatory motifs

    E-Print Network [OSTI]

    Brutlag, Doug

    A suite of web-based programs to search for transcriptional regulatory motifs Yueyi Liu, Liping Wei, the individual sites used to con- struct the motifs and the location of each site on the input sequences. The web for these three programs have been tested and published. We have since developed them into interactive web

  18. Programming and Problem Solving: A Transcript of the Spring 1999 Class

    E-Print Network [OSTI]

    Programming and Problem Solving: A Transcript of the Spring 1999 Class Columbia University Computer Science Technical Report Number CUCS­018­99 Kenneth A. Ross and Simon R. Shamoun May, 1999 This report, taught as W4995­01 during Spring 1999. The class notes were taken by the teaching assistant so

  19. Programming and Problem Solving: A Transcript of the Spring 1999 Class

    E-Print Network [OSTI]

    Programming and Problem Solving: A Transcript of the Spring 1999 Class Columbia University Computer Science Technical Report Number CUCS-018-99 Kenneth A. Ross and Simon R. Shamoun May, 1999 This report, taught as W4995-01 during Spring 1999. The class notes were taken by the teaching assistant so

  20. The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus

    E-Print Network [OSTI]

    Jiggins, Francis

    The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus that occur in response to infection with the sigma virus, a negative-stranded RNA virus (Rhabdoviridae overrepresented among the differentially expressed genes. We also found that the sigma virus alters the expression

  1. Tissue-specific alternative splicing of BK channel transcripts in Drosophila

    E-Print Network [OSTI]

    Atkinson, Nigel

    Tissue-specific alternative splicing of BK channel transcripts in Drosophila J. Y. Yu , A. B. The Drosophila slow- poke gene includes 14 alternative exons distributed among five sites of alternative splicing. Presumably, the purpose of alternative processing is to provide tran- scripts tailored to the needs

  2. Discovering functional transcription-factor combinations in the human cell cycle

    E-Print Network [OSTI]

    Church, George M.

    Discovering functional transcription-factor combinations in the human cell cycle Zhou Zhu,1 Jay-factor (TF) combinations using phylogenetically conserved sequences and microarray-based expression data of binding sites in the vicinity of one another and whether these combinations result in more coherent

  3. Splitting of H3H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange

    E-Print Network [OSTI]

    Splitting of H3­H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange RNA polymerase II. It has been long believed that histone deposition involves stable H3­H4 tetramers cells have raised the idea that preexisting H3­H4 tetramers might split into dimers, resulting in mixed

  4. Lineage specific transcriptional profiles of Symbiodinium spp. unaltered by heat stress in a coral host

    E-Print Network [OSTI]

    Palumbi, Stephen

    treatments (i.e. attributable solely to type, not heat exposure). These include many genes related to known!"#$%$ $ Lineage specific transcriptional profiles of Symbiodinium spp. unaltered by heat stress unexplored. Here, we examine the transcriptome-wide response to heat stress via RNA- Seq of two types

  5. Folding Free Energies of 59-UTRs Impact Post-Transcriptional Regulation

    E-Print Network [OSTI]

    Ringnér, Markus

    Folding Free Energies of 59-UTRs Impact Post-Transcriptional Regulation on a Genomic Scale in Yeast. Here, the aim is to study genome-wide regulatory effects of mRNA 59-UTR folding free energies. We performed computations of secondary structures in 59-UTRs and their folding free energies for all verified

  6. Genome-Wide Identification of Transcriptional Start Sites in the Plant Pathogen Pseudomonas syringae pv. tomato

    E-Print Network [OSTI]

    Myers, Chris

    syringae pv. tomato str. DC3000 Melanie J. Filiatrault1,2 *, Paul V. Stodghill1,2 , Christopher R. Myers3 identified 59-ends of transcripts for the plant pathogen Pseudomonas syringae pv. tomato str. DC3000. Citation: Filiatrault MJ, Stodghill PV, Myers CR, Bronstein PA, Butcher BG, et al. (2011) Genome

  7. Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage

    SciTech Connect (OSTI)

    Chen Chen [Department of Geriatric Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8522 (Japan); Shimizu, Shigeomi [Department of Post-Genomics Diseases, Osaka University Medical School, Suita, Osaka 565-0871 (Japan); Tsujimoto, Yoshihide [Department of Post-Genomics Diseases, Osaka University Medical School, Suita, Osaka 565-0871 (Japan); Motoyama, Noboru [Department of Geriatric Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8522 (Japan)]. E-mail: motoyama@nils.go.jp

    2005-07-29

    The tumor suppressor protein p53 plays a central role in the induction of apoptosis in response to genotoxic stress. The protein kinase Chk2 is an important regulator of p53 function in mammalian cells exposed to ionizing radiation (IR). Cells derived from Chk2-deficient mice are resistant to the induction of apoptosis by IR, and this resistance has been thought to be a result of the defective transcriptional activation of p53 target genes. It was recently shown, however, that p53 itself and histone H1.2 translocate to mitochondria and thereby induces apoptosis in a transcription-independent manner in response to IR. We have now examined whether Chk2 also regulates the transcription-independent induction of apoptosis by p53 and histone H1.2. The reduced ability of IR to induce p53 stabilization in Chk2-deficient thymocytes was associated with a marked impairment of p53 and histone H1 translocation to mitochondria. These results suggest that Chk2 regulates the transcription-independent mechanism of p53-mediated apoptosis by inducing stabilization of p53 in response to IR.

  8. Grants Management Office Guide: How Do I Find Grant Funding? GMO Guide: How Do I Find Grant Funding?

    E-Print Network [OSTI]

    New South Wales, University of

    Grants Management Office Guide: How Do I Find Grant Funding? 1 GMO Guide: How Do I Find Grant Office (GMO) updates the Current Funding Opportunities Page as soon as information on schemes opening) are a significant source of funding for Australian researchers. The GMO tracks key dates for ARC and NHMRC major

  9. EA-1928: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5: Finding of8: Finding

  10. EA-1948: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFindingDraft4: Finding ofFindingFinding of

  11. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

    E-Print Network [OSTI]

    Watanabe, Hideo

    The NKX2-1 transcription factor, a regulator of normal lung development, is the most significantly amplified gene in human lung adenocarcinoma. To study the transcriptional impact of NKX2-1 amplification, we generated an ...

  12. Finding renewable energy materials using one screensaver at a...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Finding renewable energy materials using one screensaver at a time: Combinatorial quantum chemistry for organic photovoltaics April 24, 2012 at 3pm36-428 Alan Aspuru-Guzik...

  13. Finding Large Aperture Fractures in Geothermal Resource Areas...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    A Three-Component Long-Offset Surface Seismic Survey, PSInSAR, and Kinematic Analysis Finding Large Aperture Fractures in Geothermal Resource Areas Using A Three-Component...

  14. Hepatic Portal Venous Gas: Findings on Ultrasound and CT

    E-Print Network [OSTI]

    Berona, Kristin; Hardiman, Kevin; Mailhot, Thomas

    2014-01-01

    Berona et al. Hepatic Portal Venous Gas: Findings onJ, Yazbeck T, et al. Hepatic portal venous 5. Nelson AL,D, et al. Hepatic portal venous gas: gas: physiopathology,

  15. Flexible Electronics Could Find Applications As Sensors, Artificial Muscles

    E-Print Network [OSTI]

    Rogers, John A.

    Flexible Electronics Could Find Applications As Sensors, Artificial Muscles Science Daily -- Flexible electronic structures with the potential to bend, expand and manipulate electronic devices. In addition to a biomedical impact, flexible electronics are important for energy technology as flexible

  16. Researchers use machine learning to find useful structural properties...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    using ORNL's Compute and Data Environment for Science (CADES) to analyze large volumes of neutron and x-ray scattering data to find and identify these defects-a first step to...

  17. Finding analogies in semantic networks using the singular value decomposition

    E-Print Network [OSTI]

    Krishnamurthy, Jayant (Jayant S.)

    2009-01-01

    We present CROSSBRIDGE, an algorithm for finding analogies in large, sparse semantic networks. We treat analogies as comparisons between domains of knowledge. A domain is a small semantic network, i.e., a set of concepts ...

  18. Findiing Science with Science Page 1 Finding Science with Science

    E-Print Network [OSTI]

    Stock, Kristin

    Findiing Science with Science Page 1 Finding Science with Science: Evaluating the Use Stojanovicd , Femke Reitsmae , Lukasz Korczynskif and Boyan Brodaricg a Centre for Geospatial Science of Earth and Ocean Sciences, Cardiff University, Cardiff, UK; e Department of Geography, University

  19. Jet maximization, axis minimization, and stable cone finding

    E-Print Network [OSTI]

    Thaler, Jesse

    Jet finding is a type of optimization problem, where hadrons from a high-energy collision event are grouped into jets based on a clustering criterion. As three interesting examples, one can form a jet cluster that (i) optimizes ...

  20. Energy Dept. Report Finds Major Potential to Grow Clean, Sustainable...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    new hydropower projects around the country, most of which would likely be smaller, run-of-river facilities that could utilize new low-impact designs and technologies. Find...

  1. EA-1943: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: AlternativeCommunication3-E Wholesale Power Rate Schedule8: FinalFindingMitigation ActionFinding

  2. EA-1683: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |Finding ofFinding of No

  3. EA-1684: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |Finding ofFinding of

  4. EA-1692: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |FindingProduction2: Finding

  5. EA-1706: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding ofFinding of

  6. EA-1708: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of No

  7. EA-1714: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of

  8. EA-1715: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of5:

  9. EA-1719: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding

  10. EA-1722: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding0::

  11. EA-1726: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5: Finding

  12. EA-1762: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding2: Finding

  13. EA-1763: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding2: Finding3:

  14. EA-1790: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: FindingFinding

  15. EA-1791: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: FindingFinding1:

  16. EA-1824: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartmentFinding4: Finding of

  17. EA-1929: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5: Finding

  18. Low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism

    SciTech Connect (OSTI)

    Sheng, Zhi-Guo; Tang, Yuan; Liu, Yu-Xiang; Yuan, Ye; Zhao, Bao-Quan; Chao, Xi-Juan; Zhu, Ben-Zhan

    2012-02-15

    Bisphenol (BPA) is one of the highest-volume chemicals produced worldwide, and human exposure to BPA is thought to be ubiquitous. Various rodent and in vitro studies have shown that thyroid hormone (TH) function can be impaired by BPA. However, it is still unknown if low concentrations of BPA can suppress the thyroid hormone receptor (TR) transcription. The present study aims to investigate the possible suppressing effects of low concentrations of BPA on TR transcription and the involved mechanism(s) in CV-1 cells derived from cercopithecus aethiops monkey kidneys. Using gene reporter assays, BPA at concentrations as low as 10{sup ?9} M suppresses TR or steroid receptor coactivator-1(SRC-1)-enhanced TR transcription, but not reducing TR/SRC-1 interaction in mammalian two-hybrid and glutathione S-transferase pull-down studies. It has been further shown that both nuclear receptor co-repressor (N-CoR) and silencing mediator for retinoid and thyroid hormone receptors (SMRT) are recruited to the TR-?1 by BPA in the presence of physiologic concentrations of T3 or T4. However, the overexpression of ?3 integrin or c-Src significantly reduces BPA-induced recruitment of N-CoR/SMRT to TR or suppression of TR transcription. Furthermore, BPA inhibits the T3/T4-mediated interassociation of the ?3 integrin/c-Src/MAPK/TR-?1 pathways by the co-immunoprecipitation. These results indicate that low concentrations of BPA suppress the TR transcription by disrupting physiologic concentrations of T3/T4-mediated ?3 integrin/c-Src/MAPK/TR-?1 pathways, followed by recruiting N-CoR/SMRT to TR-?1, providing a novel insight regarding the TH disruption effects of low concentration BPA. -- Highlights: ? Environmentally relevant concentrations of BPA suppress TR transcription. ? BPA recruits the N-CoR/SMRT to TR under the physiologic concentrations of T3/T4. ? BPA disrupts T3/T4-mediated ?3 integrin/c-Src/MAPK/TR-?1 pathways.

  19. Regulation of zebrafish CYP3A65 transcription by AHR2

    SciTech Connect (OSTI)

    Chang, Chin-Teng; Chung, Hsin-Yu; Su, Hsiao-Ting; Tseng, Hua-Pin [Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan (China); Tzou, Wen-Shyong [Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan (China); Center of Excellence for Marine Bioenvironment and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan (China); Hu, Chin-Hwa, E-mail: chhu@mail.ntou.edu.tw [Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan (China); Center of Excellence for Marine Bioenvironment and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan (China)

    2013-07-15

    CYP3A proteins are the most abundant CYPs in the liver and intestines, and they play a pivotal role in drug metabolism. In mammals, CYP3A genes are induced by various xenobiotics through processes mediated by PXR. We previously identified zebrafish CYP3A65 as a CYP3A ortholog that is constitutively expressed in gastrointestinal tissues, and is upregulated by treatment with dexamethasone, rifampicin or tetrachlorodibenzo-p-dioxin (TCDD). However, the underlying mechanism of TCDD-mediated CYP3A65 transcription is unclear. Here we generated two transgenic zebrafish, Tg(CYP3A65S:EGFP) and Tg(CYP3A65L:EGFP), which contain 2.1 and 5.4 kb 5? flanking sequences, respectively, of the CYP3A65 gene upstream of EGFP. Both transgenic lines express EGFP in larval gastrointestinal tissues in a pattern similar to that of the endogenous CYP3A65 gene. Moreover, EGFP expression can be significantly induced by TCDD exposure during the larval stage. In addition, EGFP expression can be stimulated by kynurenine, a putative AHR ligand produced during tryptophan metabolism. AHRE elements in the upstream regulatory region of the CYP3A65 gene are indispensible for basal and TCDD-induced transcription. Furthermore, the AHR2 DNA and ligand-binding domains are required to mediate effective CYP3A65 transcription. AHRE sequences are present in the promoters of many teleost CYP3 genes, but not of mammalian CYP3 genes, suggesting that AHR/AHR2-mediated transcription is likely a common regulatory mechanism for teleost CYP3 genes. It may also reflect the different environments that terrestrial and aquatic organisms encounter. - Highlights: • Tg(CYP3A65:EGFP) and CYP3A65 exhibits identical expression pattern. • CYP3A65 can be significantly induced by TCDD or kynurenine. • The AHRE elements are required to mediate CYP3A65 transcription. • The AHR2 DNA and ligand-binding domains are required for CYP3A65 transcription. • AHRE elements are present in many teleost CYP3 genes, but not in mammalian CYP3 genes.

  20. The ASKAP/EMU Source Finding Data Challenge

    E-Print Network [OSTI]

    Hopkins, A M; Seymour, N; Chow, K E; Norris, R P; Bonavera, L; Breton, R; Carbone, D; Ferrari, C; Franzen, T M O; Garsden, H; Gonzalez-Nuevo, J; Hales, C A; Hancock, P J; Heald, G; Herranz, D; Huynh, M; Jurek, R J; Lopez-Caniego, M; Massardi, M; Mohan, N; Molinari, S; Orru, E; Paladino, R; Pestalozzi, M; Pizzo, R; Rafferty, D; Rottgering, H J A; Rudnick, L; Schisano, E; Shulevski, A; Swinbank, J; Taylor, R; van der Horst, A J

    2015-01-01

    The Evolutionary Map of the Universe (EMU) is a proposed radio continuum survey of the Southern Hemisphere up to declination +30 deg., with the Australian Square Kilometre Array Pathfinder (ASKAP). EMU will use an automated source identification and measurement approach that is demonstrably optimal, to maximise the reliability, utility and robustness of the resulting radio source catalogues. As part of the process of achieving this aim, a "Data Challenge" has been conducted, providing international teams the opportunity to test a variety of source finders on a set of simulated images. The aim is to quantify the accuracy of existing automated source finding and measurement approaches, and to identify potential limitations. The Challenge attracted nine independent teams, who tested eleven different source finding tools. In addition, the Challenge initiators also tested the current ASKAPsoft source-finding tool to establish how it could benefit from incorporating successful features of the other tools. Here we p...

  1. Finding influential spreaders from human activity beyond network location

    E-Print Network [OSTI]

    Min, Byungjoon; Makse, Hernán A

    2015-01-01

    Most centralities proposed for identifying influential spreaders on social networks to either spread a message or to stop an epidemic require the full topological information of the network on which spreading occurs. In practice, however, collecting all connections between agents in social networks can be hardly achieved. As a result, such metrics could be difficult to apply to real social networks. Consequently, a new approach for identifying influential people without the explicit network information is demanded in order to provide an efficient immunization or spreading strategy, in a practical sense. In this study, we seek a possible way for finding influential spreaders by using the social mechanisms of how social connections are formed in real networks. We find that a reliable immunization scheme can be achieved by asking people how they interact with each other. From these surveys we find that the probabilistic tendency to connect to a hub has the strongest predictive power for influential spreaders amo...

  2. Curved track segment finding using Tiny Triplet Finder (TTF)

    SciTech Connect (OSTI)

    Wu, Jin-Yuan; Wang, M.; Gottschalk, E.; Shi, Z.; /Fermilab

    2006-11-01

    We describe the applications of a track segment recognition scheme called the Tiny Triplet Finder (TTF) that involves the grouping of three hits satisfying a constraint forming of a track segment. The TTF was originally developed solving straight track segment finding problem, however, it is also suitable in many curved track segment finding problems. The examples discussed in this document are among popular detector layouts in high-energy/nuclear physics experiments. Although it is not practical to find a universal recipe for arbitrary detector layouts, the method of the TTF application is illustrated via the discussion of the examples. Generally speaking, whenever the data item to be found in a pattern recognition problem contains two free parameters, and if the constraint connecting the measurements and the two free parameters has an approximate shift invariant property, the Tiny Triplet Finder can be used.

  3. Nuclear Electric Propulsion Technology Panel findings and recommendations

    SciTech Connect (OSTI)

    Doherty, M.P.

    1992-01-01

    Summarized are the findings and recommendations of a triagency (NASA/DOE/DOD) panel on Nuclear Electric Propulsion (NEP) Technology. NEP has been identified as a candidate nuclear propulsion technology for exploration of the Moon and Mars as part of the Space Exploration Initiative (SEI). The findings are stated in areas of system and subsystem considerations, technology readiness, and ground test facilities. Recommendations made by the panel are summarized concerning: (1) existing space nuclear power and propulsion programs, and (2) the proposed multiagency NEP technology development program.

  4. EA-1976: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: AlternativeCommunication3-E Wholesale Power Rate Schedule8:5: Finding ofFinding of No Significant

  5. EA-1440: Finding of No Signficant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91: Final3:38:Finding: Finding of

  6. EA-1533: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding of No33: FinalFinding

  7. EA-1539: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding of No33:9: Finding of

  8. EA-1562: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding of No33:9:Finding of

  9. EA-1576: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding6: Finding of No

  10. EA-1602: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding6:Mitigation2: Finding

  11. EA-1605: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding6:Mitigation2:Finding

  12. EA-1705: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding ofFinding of No

  13. EA-1709: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of No9:

  14. EA-1713: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of No9:3:

  15. EA-1716: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of5:6:

  16. EA-1718: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8: Finding of5:6:8:

  17. EA-1725: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5: Finding of No

  18. EA-1727: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5:7: Finding of No

  19. EA-1729: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5:7:9: Finding of

  20. EA-1731: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5:7:9: Finding

  1. EA-1826: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartmentFinding4:FinalFinding

  2. EA-1888: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE NoticeFinal Environmental7: FindingFinding

  3. EA-1921: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding ofDepartmentFinding of

  4. EA-1922: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding ofDepartmentFinding

  5. EA-1925: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5: Finding of No

  6. EA-1933: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5:2: DraftFinding of No

  7. EA-1938: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5:2:DraftFinal8: Finding

  8. EA-1947: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFindingDraft4: Finding ofFinding of No

  9. EA-1954: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFindingDraft4: FindingLine; BentonFinding

  10. EA-1991: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8:Final78: Sand Creeknautical milesFindingFinding

  11. EA-2001: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:IAbout Us|ofElizabethEnergy85: Finding ofFinding of

  12. EA-2017: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:IAbout Us|ofElizabethEnergy85: FindingPublicFinding

  13. A Weighted Residual Framework for Formulation and Analysis of Direct Transcription Methods for Optimal Control 

    E-Print Network [OSTI]

    Singh, Baljeet

    2012-02-14

    . I am grateful to my roommates Surinder Pal and Navdeep Singh for making my stay at TAMU much like home. I thank my colleagues and friends, Hrishikesh, Shalom, Luis, Avinash, Roshmik, Parikshit, Sandeep, Abhishek, Xiaoli, Monika and Mrinal...-1 A WEIGHTED RESIDUAL FRAMEWORK FOR FORMULATION AND ANALYSIS OF DIRECT TRANSCRIPTION METHODS FOR OPTIMAL CONTROL A Dissertation by BALJEET SINGH Submitted to the O ce of Graduate Studies of Texas A&M University in partial ful llment...

  14. Find It. Delete It. Protect It. Information Technology Security Strategy

    E-Print Network [OSTI]

    Sheridan, Jennifer

    Find It. Delete It. Protect It. Information Technology Security Strategy Executive Summary The general proposed strategy is to optimize risk management for information security incrementally and over that security will be a process rather than project. Achievement of the goal, optimized risk management

  15. Find Teacher & Classroom Resources Health & Physical Education, K Grade 6

    E-Print Network [OSTI]

    Fletcher, Robin

    Find Teacher & Classroom Resources for Health & Physical Education, K ­ Grade 6 Queen's Library weeks Books, Lesson Resources, K-12 books, Multimedia, Ministry of Education documents For use Type of Resource Search Tip Ministry of Education documents Browsing Tip: All M of E documents

  16. Strategies for finding government information by older people

    E-Print Network [OSTI]

    Curzon, Paul

    -government agenda, suggested it was inevitable that online information sources would become the primary means for achieving an individual's personal aims of using the internet over other information sources. We doStrategies for finding government information by older people Paul Curzon, Suzette Keith, Gill

  17. The Value of Academic Libraries: Findings and Implications for the

    E-Print Network [OSTI]

    Oakleaf, Megan

    libraries in the future. #12;Recommendations #12; Define outcomes Create or adopt systems for assessment;Define outcomes. #12;Use existing data. #12;Develop systems to collect data on individual library userThe Value of Academic Libraries: Findings and Implications for the Profession Lisa Janicke

  18. Finding True Beliefs: Applying Rank-Dependent Expected Utility Theory

    E-Print Network [OSTI]

    Chen, Yiling

    -making that incorporates probability weighting and non-linear utility functions, to the analysis of the quadratic scoringFinding True Beliefs: Applying Rank-Dependent Expected Utility Theory to Proper Scoring Rules-value maximizers. Thus, we apply rank-dependent expected utility theory, a more general model of decision

  19. FINDINGS IN BRIEF THEME: Water, aquaculture and fish

    E-Print Network [OSTI]

    FINDINGS IN BRIEF THEME: Water, aquaculture and fish Photo:Jan-ErikJohansson,SLU Sustainable feed for farmed fish Farmed predatory fish (salmon, cod, etc.) need large quantities of feed, which at pre- sent consists of wildcaught marine fish spe- cies that are endangered to varying degrees. SLU researchers have

  20. Preliminary Findings from an Analysis of Building Energy Information System

    E-Print Network [OSTI]

    -based energy monitoring, web-based energy management linked to controls, demand response, and enterprise energyLBNL-2224E Preliminary Findings from an Analysis of Building Energy Information System Technologies of Building Energy Information System Technologies Jessica Granderson Mary Ann Piette Girish Ghatikar Phillip

  1. Finding frequent substructures in chemical compounds Luc Dehaspe

    E-Print Network [OSTI]

    Toivonen, Hannu

    @aber.ac.uk Abstract The discovery of the relationships between chemical structure and biological function is centralFinding frequent substructures in chemical compounds Luc Dehaspe Dept. of Computer Science chemical carcino­ genicity. This toxicology application was launched at IJCAI'97 as a research challenge

  2. Instruction Guide Paying Vendors: Using the Find an Existing

    E-Print Network [OSTI]

    Watson, Craig A.

    . Enter a Voucher ID number to begin a search. For this example, enter "03036649". Click the Search of Florida, Gainesville, FL 32611 OVERVIEW Search for a voucher and retrieve the original voucher screen, click on Regular Entry. Click the Find an Existing Value tab. Example 1 Searching by Voucher ID 1

  3. Finding the needle in the haystack: Algorithms for conformational optimization

    SciTech Connect (OSTI)

    Andricioaei, I.; Straub, J.E.

    1996-09-01

    Algorithms are given for comformational optimization of proteins. The protein folding problems is regarded as a problem of global energy mimimization. Since proteins have hundreds of atoms, finding the lowest-energy conformation in a many-dimensional configuration space becomes a computationally demanding problem.{copyright} {ital American Institute of Physics.}

  4. 2003 UBC FOOD SYSTEM COLLABORATIVE PROJECT: SUMMARY OF FINDINGS

    E-Print Network [OSTI]

    2003 UBC FOOD SYSTEM COLLABORATIVE PROJECT: SUMMARY OF FINDINGS Kristina Bouris Campus Sustainability Office September 12, 2003 The UBC Food Systems Project is a collaborative project between Development Studies (UBC SEEDS) program of the UBC Campus Sustainability Office, UBC Food and Beverage

  5. Finding Chemical Reaction Paths with a Multilevel Preconditioning Seyit Kale,,

    E-Print Network [OSTI]

    Dinner, Aaron

    Finding Chemical Reaction Paths with a Multilevel Preconditioning Protocol Seyit Kale,, Olaseni for chemical reactions can be computationally costly owing to the level of quantum- chemical theory needed for the reaction path iteratively. These methods have yielded important insights in quantum chemical contexts9

  6. Finding the ciliary beating pattern with optimal efficiency

    E-Print Network [OSTI]

    Osterman, Natan

    Finding the ciliary beating pattern with optimal efficiency Natan Ostermana,b and Andrej Vilfana, and approved July 20, 2011 (received for review May 17, 2011) We introduce a measure for energetic efficiency according to this criterion. Maximizing the efficiency of a single cilium leads to curly, often symmetric

  7. Portfolio: A Search Engine for Finding Functions and Their Usages

    E-Print Network [OSTI]

    Poshyvanyk, Denys

    Libraries]: Reusable Libraries General Terms Algorithms, Experimentation Keywords source code search engines file. He or she may enter the query "edit save pdf file" into a search engine. Existing source codePortfolio: A Search Engine for Finding Functions and Their Usages Collin McMillan College

  8. A Guide to Finding Protein Information on the Internet

    E-Print Network [OSTI]

    Hill, Chris

    A Guide to Finding Protein Information on the Internet Alexander Simon Hill Lab University of Utah exist for collecting, analyzing, and synthesizing biological information on the Internet. However. The search process is complicated by characteristics of the Internet such as its rapid rate of growth

  9. Finding mold removal directions using graphics hardware Rahul Khardekar

    E-Print Network [OSTI]

    McMains, Sara

    Finding mold removal directions using graphics hardware Rahul Khardekar University of California, Berkeley Sara McMains University of California, Berkeley 1 Introduction In molding and casting manufacturing processes, molten raw ma- terial is shaped in molds from which the resulting part must be re

  10. Local Algorithms for Finding Interesting Individuals in Large Networks

    E-Print Network [OSTI]

    Ives, Zachary G.

    or interests in so- cial networks such as Facebook, and other mechanisms that may return vertices would we actually find them -- especially considering that for many such networks (including the Web, or for non- employee researchers of online social networks such as Facebook), there may not exist an acces

  11. On Finding Narrow Passages with Probabilistic Roadmap Planners

    E-Print Network [OSTI]

    Latombe, Jean-Claude

    On Finding Narrow Passages with Probabilistic Roadmap Planners David Hsu, Stanford University University, Stanford, CA, USA A probabilistic roadmap is a network of simple paths connecting collision­free configurations obtained by sampling a robot's configuration space at random. Several probabilistic roadmap

  12. DIMACS Technical Report 9505 FINDING CUTS IN THE TSP

    E-Print Network [OSTI]

    instances of the traveling salesman problem. Some of these instances arise from drilling holes in printed with the cost of travel between each pair of them, find the cheapest way of visiting all the cities and returning to your starting point. (The travel costs are symmetric in the sense that traveling from city X

  13. Energize your career Find out how UC Davis Extension's

    E-Print Network [OSTI]

    California at Davis, University of

    gas purchasing opportunities in the spot market, thermal energy storage, alterna- tive energy supplies, energy security and energy trading. Explore reliability and risk analysis methods, financing projectsEnergize your career Find out how UC Davis Extension's convenient, online Energy Resource

  14. Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14ARF tumor suppressor

    SciTech Connect (OSTI)

    Dimri, Goberdhan P.; Itahana, Koji; Acosta, Meileen; Campisi, Judith

    1999-11-05

    Normal cells do not divide indefinitely due to a process known as replicative senescence. Human cells arrest growth with a senescent phenotype when they acquire one or more critically short telomere as a consequence of cell division. Recent evidence suggests that certain types of DNA damage, chromatin remodeling, or oncogenic forms of Rasor Raf can also elicit a senescence response. We show here that E2F1, a multifunctional transcription factor that binds the retinoblastoma (pRb) tumor suppressor and can either promote or suppress tumorigenesis, induces a senescent phenotype when overexpressed in normal human fibroblasts. Normal human cells stably arrested proliferation and expressed several markers of replicative senescence in response to E2F1. This activity of E2F1 was independent of its pRb binding activity, but dependent on its ability to stimulate gene expression. The E2F1 target gene critical for the senescence response appeared to be the p14ARF tumor suppressor. Replicatively senescent human fibroblasts overexpressed p14ARF, and ectopic expression of p14ARF in presenescent cells induced a phenotype similar to that induced by E2F1. Consistent with a critical role for p14ARF, cells with compromised p53 function were immune to senescence induction by E2F1, as were cells deficient in p14ARF. Our findings support the idea that the senescence response is a critical tumor suppressive mechanism, provide an explanation for the apparently paradoxical roles of E2F1 in oncogenesis, and identify p14ARF as a potentially important mediator of the senescent phenotype.

  15. Cartilage mechanobiology and transcriptional effects of combined mechanical compression and IGF-1 stimulation on bovine cartilage explants

    E-Print Network [OSTI]

    Wheeler, Cameron, 1978-

    2007-01-01

    Background: Investigators have focused on mechano-regulation of upstream signaling and responses at the level of gene transcription, protein translation and post-translational modifications. Intracellular pathways including ...

  16. Last Updated: October 5, 2011 1 iSiS -Generating an Unofficial Transcript via Faculty Center

    E-Print Network [OSTI]

    Massachusetts at Lowell, University of

    Last Updated: October 5, 2011 1 iSiS - Generating an Unofficial Transcript via Faculty Center 1 browser as a trusted site. For instructions: http://www.uml.edu/enrollment/isis

  17. Transcriptional silencing of ?-globin by BCL11A involves long-range interactions and cooperation with SOX6

    E-Print Network [OSTI]

    Xu, Jian

    The developmental switch from human fetal (?) to adult (?) hemoglobin represents a clinically important example of developmental gene regulation. The transcription factor BCL11A is a central mediator of ?-globin silencing ...

  18. A genome-wide regulatory network identifies key transcription factors for memory CD8[superscript +] T-cell development

    E-Print Network [OSTI]

    Hu, Guangan

    Memory CD8[superscript +] T-cell development is defined by the expression of a specific set of memory signature genes. Despite recent progress, many components of the transcriptional control of memory CD8[superscript +] ...

  19. Transcriptional response of O?-methylguanine methyltransferase deficient yeast to methyl-N-nitro-N-nitrosoguanidine (MNNG)

    E-Print Network [OSTI]

    Rao, Anoop, 1977-

    2004-01-01

    (cont.) of transcription factors and subsequently, induction of RNA processing (35% of genes incrementally induced) and kinases involved in protein phosphorylation. In the WT, the response was restricted to a transient ...

  20. Proteomic and transcriptional analysis of components of the DNA replication and repair machinery in mouse embryonic stem cells

    E-Print Network [OSTI]

    Sellami, Nadia

    2013-01-01

    Origin recognition complex (ORC) mediates histone 3 lysine 4transcription. Silence of the ORCs. Curr. Biol. CB 4, 238–Rbf1 interacts with ORC and associates with chromatin in an

  1. Composite RNAi-Microsponges Form through Self-Assembly of the Organic and Inorganic Products of Transcription

    E-Print Network [OSTI]

    Roh, Young Hoon

    Inorganic nanostructures have been used extensively to package nucleic acids into forms useful for therapeutic applications. Here we report that the two products of transcription, RNA and inorganic pyrophosphate, can ...

  2. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights

    E-Print Network [OSTI]

    Gordan, Raluca

    Background: Transcription factors (TFs) play a central role in regulating gene expression by interacting with cis-regulatory DNA elements associated with their target genes. Recent surveys have examined the DNA binding ...

  3. Novel stochastic and entropy-based Expectation-Maximisation algorithm for transcription factor binding site motif discovery 

    E-Print Network [OSTI]

    Kilpatrick, Alastair Morris

    2015-06-29

    The discovery of transcription factor binding site (TFBS) motifs remains an important and challenging problem in computational biology. This thesis presents MITSU, a novel algorithm for TFBS motif discovery which exploits ...

  4. CITED2 modulates estrogen receptor transcriptional activity in breast cancer cells

    SciTech Connect (OSTI)

    Lau, Wen Min; Doucet, Michele; Huang, David; Weber, Kristy L.; Kominsky, Scott L.

    2013-07-26

    Highlights: •The effects of elevated CITED2 on ER function in breast cancer cells are examined. •CITED2 enhances cell growth in the absence of estrogen and presence of tamoxifen. •CITED2 functions as a transcriptional co-activator of ER in breast cancer cells. -- Abstract: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) is a member of the CITED family of non-DNA binding transcriptional co-activators of the p300/CBP-mediated transcription complex. Previously, we identified CITED2 as being overexpressed in human breast tumors relative to normal mammary epithelium. Upon further investigation within the estrogen receptor (ER)-positive subset of these breast tumor samples, we found that CITED2 mRNA expression was elevated in those associated with poor survival. In light of this observation, we investigated the effect of elevated CITED2 levels on ER function. While ectopic overexpression of CITED2 in three ER-positive breast cancer cell lines (MCF-7, T47D, and CAMA-1) did not alter cell proliferation in complete media, growth was markedly enhanced in the absence of exogenous estrogen. Correspondingly, cells overexpressing CITED2 demonstrated reduced sensitivity to the growth inhibitory effects of the selective estrogen receptor modulator, 4-hydroxytamoxifen. Subsequent studies revealed that basal ER transcriptional activity was elevated in CITED2-overexpressing cells and was further increased upon the addition of estrogen. Similarly, basal and estrogen-induced expression of the ER-regulated genes trefoil factor 1 (TFF1) and progesterone receptor (PGR) was higher in cells overexpressing CITED2. Concordant with this observation, ChIP analysis revealed higher basal levels of CITED2 localized to the TFF-1 and PGR promoters in cells with ectopic overexpression of CITED2, and these levels were elevated further in response to estrogen stimulation. Taken together, these data indicate that CITED2 functions as a transcriptional co-activator of ER in breast cancer cells and that its increased expression in tumors may result in estrogen-independent ER activation, thereby reducing estrogen dependence and response to anti-estrogen therapy.

  5. Transcriptional analysis of chicken immune cells following exposure to 2,3,7,8,-tetrachlorodibenzo-p-dioxin (TCDD) 

    E-Print Network [OSTI]

    Puebla-Osorio, Nahum

    2006-04-12

    -1 TRANSCRIPTIONAL ANALYSIS OF CHICKEN IMMUNE CELLS FOLLOWING EXPOSURE TO 2,3,7,8-TETRACHLORODIBENZO- p-DIOXIN (TCDD) A Dissertation by NAHUM PUEBLA-OSORIO Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of the requirements for the degree of DOCTOR OF PHILOSOPHY December 2004 Major Subject: Poultry Science TRANSCRIPTIONAL ANALYSIS OF CHICKEN IMMUNE CELLS FOLLOWING EXPOSURE TO 2,3,7,8-TETRACHLORODIBENZO- p-DIOXIN (TCDD) A...

  6. The oncoprotein HBXIP upregulates PDGFB via activating transcription factor Sp1 to promote the proliferation of breast cancer cells

    SciTech Connect (OSTI)

    Zhang, Yingyi; Zhao, Yu; Li, Leilei; Shen, Yu; Cai, Xiaoli; Zhang, Xiaodong; Ye, Lihong

    2013-05-03

    Highlights: •HBXIP is able to upregulate the expression of PDGFB in breast cancer cells. •HBXIP serves as a coactivator of activating transcription factor Sp1. •HBXIP stimulates the PDGFB promoter via activating transcription factor Sp1. •HBXIP promotes the proliferation of breast cancer cell via upregulating PDGFB. -- Abstract: We have reported that the oncoprotein hepatitis B virus X-interacting protein (HBXIP) acts as a novel transcriptional coactivator to promote proliferation and migration of breast cancer cells. Previously, we showed that HBXIP was able to activate nuclear factor-?B (NF-?B) in breast cancer cells. As an oncogene, the platelet-derived growth factor beta polypeptide (PDGFB) plays crucial roles in carcinogenesis. In the present study, we found that both HBXIP and PDGFB were highly expressed in breast cancer cell lines. Interestingly, HBXIP was able to increase transcriptional activity of NF-?B through PDGFB, suggesting that HBXIP is associated with PDGFB in the cells. Moreover, HBXIP was able to upregulate PDGFB at the levels of mRNA, protein and promoter in the cells. Then, we identified that HBXIP stimulated the promoter of PDGFB through activating transcription factor Sp1. In function, HBXIP enhanced the proliferation of breast cancer cells through PDGFB in vitro. Thus, we conclude that HBXIP upregulates PDGFB via activating transcription factor Sp1 to promote proliferation of breast cancer cells.

  7. 2. Find the inverse of 23 in Z71 3. Find the last two digits of 15100. 4.

    E-Print Network [OSTI]

    2015-09-28

    Find the inverse of 23 in Z71 .... D12 = {e, r, r2,r3,r4,r5, s, sr, sr2, sr3, sr4, sr5,}. ... Since risr = sr?i+1, and srir = sri+1 ri = r?i for i = 1,2,4,5 then these elements are ...

  8. New way to predict plutonium Finding could lead to

    E-Print Network [OSTI]

    Savrasov, Sergej Y.

    New way to predict plutonium safety Finding could lead to improved storage of nuclear weapons of 2Science Front Page 2:14 PM ET Thursday, April 12, 2001 9/5/2003file://E:\\Homepages\\SavrasovHome\\Projects\\Research\\Plutonium, and Privacy Page 2 of 2Science Front Page 2:14 PM ET Thursday, April 12, 2001 9/5/2003file://E:\\Homepages\\SavrasovHome\\Projects\\Research\\Plutonium

  9. EA-1611: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinal Environmental AssessmentEnergyFinding of

  10. EA-1613: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinal Environmental AssessmentEnergyFinding3:

  11. EA-1631: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinal EnvironmentalFinalMitigation1: Finding of No

  12. EA-1634: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinal EnvironmentalFinalMitigation1: Finding of

  13. EA-1635: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinal EnvironmentalFinalMitigation1: Finding of5:

  14. EA-1640: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinal EnvironmentalFinalMitigation1:Impact |Finding

  15. EA-1656: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN | Department ofFinding of No

  16. EA-1658: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN | Department ofFinding of

  17. EA-1664: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN | Department ofFinding

  18. EA-1665: Final Environmental Assessment and Finding of No Significant

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN | Department ofFindingImpact

  19. EA-1673: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN | DepartmentEA-1673: Finding

  20. EA-1679: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |Finding of No Significant

  1. EA-1685: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |Finding

  2. EA-1690: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |FindingProduction

  3. EA-1696: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN |FindingProduction2:6:

  4. EA-1698: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding of No Significant

  5. EA-1699: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding of No Significant9:

  6. EA-1700: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding of No

  7. EA-1704: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding of Noof

  8. EA-1723: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:

  9. EA-1728: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5:7:

  10. EA-1736: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA |Finding of No

  11. EA-1739: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA |Finding

  12. EA-1743: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding of

  13. EA-1746: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding6:

  14. EA-1752: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0:Finding

  15. EA-1753: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0:Finding3:

  16. EA-1758: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding of No

  17. EA-1759: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding of9:

  18. EA-1767: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding2:

  19. EA-1769: Final Environmental Assessment and Finding of No Significant

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding2:Impact |

  20. EA-1770: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding2:Impact |0:

  1. EA-1772: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding2:Impact

  2. EA-1776: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,:Department6: Finding

  3. EA-1785: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: Finding of No

  4. EA-1786: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: Finding of No6:

  5. EA-1787: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: Finding of

  6. EA-1788: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: Finding of8:

  7. EA-1793: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,DeliverablesDraftFinding of No

  8. EA-1795: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,DeliverablesDraftFinding

  9. EA-1812: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0: Finding

  10. EA-1819: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartmentFinding of No

  11. EA-1820: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartmentFinding of

  12. EA-1823: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartmentFinding

  13. EA-1832: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: Finding of No

  14. EA-1833: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: Finding of No3:

  15. EA-1836: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: Finding of6:

  16. EA-1839: Final Environmental Assessment and Finding of No Significant

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: Finding

  17. EA-1840: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: FindingCA

  18. EA-1846: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32:FinalFinding

  19. EA-1848: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32:FinalFinding8:

  20. EA-2004: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:IAbout Us|ofElizabethEnergy85: Finding

  1. Inhibition of hepatitis B virus (HBV) by LNA-mediated nuclear interference with HBV DNA transcription

    SciTech Connect (OSTI)

    Sun, Zhen; Department of Biochemistry and Molecular Biology, Program in Molecular Cell Biology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058 ; Xiang, Wenqing; Guo, Yajuan; Chen, Zhi; Liu, Wei; Lu, Daru

    2011-06-10

    Highlights: {yields} LNA-modified oligonucleotides can pass through the plasma membrane of cultured cells even without using transfection machinery. {yields} LNA-modified oligonucleotides passed efficiently across the cell membrane, and lipid-coating facilitated translocation from the cytoplasm to the nucleus. {yields} LNA-oligonucleotide designed to target nuclear HBV DNA efficiently suppresses HBV replication and transcription in cultured hepatic cells. -- Abstract: Silencing target genes with small regulatory RNAs is widely used to investigate gene function and therapeutic drug development. Recently, triplex-based approaches have provided another attractive means to achieve targeted gene regulation and gene manipulation at the molecular and cellular levels. Nuclear entry of oligonucleotides and enhancement of their affinity to the DNA targets are key points of such approaches. In this study, we developed lipid-based transport of a locked-nucleic-acid (LNA)-modified oligonucleotide for hepatitis B virus (HBV) DNA interference in human hepatocytes expressing HBV genomic DNA. In these cells, the LNA-modified oligonucleotides passed efficiently across the cell membrane, and lipid-coating facilitated translocation from the cytoplasm to the nucleus. The oligonucleotide specifically targeting HBV DNA clearly interfered with HBV DNA transcription as shown by a block in pregenomic RNA (pgRNA) production. The HBV DNA-targeted oligonucleotide suppressed HBV DNA replication and HBV protein production more efficiently than small interfering RNAs directed to the pgRNA. These results demonstrate that fusion with lipid can carry LNA-modified oligonucleotides to the nucleus where they regulate gene expression. Interfering with HBV DNA transcription by LNA-modified oligonucleotides has strong potential as a new strategy for HBV inhibition.

  2. Transcription Factor Amr1 Induces Melanin Biosynthesis and Suppresses Virulence in Alternaria brassicicola

    SciTech Connect (OSTI)

    Cho, Yangrae; Srivastava, Akhil; Ohm, Robin A.; Lawrence, Christopher B.; Wang, Koon-Hui; Grigoriev, Igor V.; Marahatta, Sharadchandra P.

    2012-05-01

    Alternaria brassicicola is a successful saprophyte and necrotrophic plant pathogen. Several A. brassicicola genes have been characterized as affecting pathogenesis of Brassica species. To study regulatory mechanisms of pathogenesis, we mined 421 genes in silico encoding putative transcription factors in a machine-annotated, draft genome sequence of A. brassicicola. In this study, targeted gene disruption mutants for 117 of the transcription factor genes were produced and screened. Three of these genes were associated with pathogenesis. Disruption mutants of one gene (AbPacC) were nonpathogenic and another gene (AbVf8) caused lesions less than half the diameter of wild-type lesions. Unexpectedly, mutants of the third gene, Amr1, caused lesions with a two-fold larger diameter than the wild type and complementation mutants. Amr1 is a homolog of Cmr1, a transcription factor that regulates melanin biosynthesis in several fungi. We created gene deletion mutants of ?amr1 and characterized their phenotypes. The ?amr1 mutants used pectin as a carbon source more efficiently than the wild type, were melanin-deficient, and more sensitive to UV light and glucanase digestion. The AMR1 protein was localized in the nuclei of hyphae and in highly melanized conidia during the late stage of plant pathogenesis. RNA-seq analysis revealed that three genes in the melanin biosynthesis pathway, along with the deleted Amr1 gene, were expressed at low levels in the mutants. In contrast, many hydrolytic enzyme-coding genes were expressed at higher levels in the mutants than in the wild type during pathogenesis. The results of this study suggested that a gene important for survival in nature negatively affected virulence, probably by a less efficient use of plant cell-wall materials. We speculate that the functions of the Amr1 gene are important to the success of A. brassicicola as a competitive saprophyte and plant parasite.

  3. ECRbase: Database of Evolutionary Conserved Regions, Promoters, and Transcription Factor Binding Sites in Vertebrate Genomes

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Loots, Gabriela G. [LLNL; Ovcharenko, I. [LLNL

    Evolutionary conservation of DNA sequences provides a tool for the identification of functional elements in genomes. This database of evolutionary conserved regions (ECRs) in vertebrate genomes features a database of syntenic blocks that recapitulate the evolution of rearrangements in vertebrates and a comprehensive collection of promoters in all vertebrate genomes generated using multiple sources of gene annotation. The database also contains a collection of annotated transcription factor binding sites (TFBSs) in evolutionary conserved and promoter elements. ECRbase currently includes human, rhesus macaque, dog, opossum, rat, mouse, chicken, frog, zebrafish, and fugu genomes. (taken from paper in Journal: Bioinformatics, November 7, 2006, pp. 122-124

  4. Transcription factor co-localization patterns affect human cell type-specific gene expression.

    E-Print Network [OSTI]

    Wang, Dennis; Rendon, Augusto; Ouwehand, Willem; Wernisch, Lorenz

    2012-06-21

    Wang et al. BMC Genomics 2012, 13:263 http://www.biomedcentral.com/1471-2164/13/263 RESEARCH ARTICLE Open Access Transcription factor co-localization patterns affect human cell type-specific gene expression Dennis Wang1*, Augusto Rendon2, Willem... identified thousands of regions along the *Correspondence: dennis.wang@mrc-bsu.cam.ac.uk 1MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, UK Full list of author information is available at the end of the article human genome where...

  5. Comments on Different techniques for finding best-fit parameters

    SciTech Connect (OSTI)

    Fenimore, Edward E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Triplett, Laurie A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-07-01

    A common data analysis problem is to find best-fit parameters through chi-square minimization. Levenberg-Marquardt is an often used system that depends on gradients and converges when successive iterations do not change chi-square more than a specified amount. We point out in cases where the sought-after parameter weakly affects the fit and cases where the overall scale factor is a parameter, that a Golden Search technique can often do better. The Golden Search converges when the best-fit point is within a specified range and that range can be made arbitrarily small. It does not depend on the value of chi-square.

  6. Transportation Energy Futures: Project Overview and Findings (Presentation)

    SciTech Connect (OSTI)

    Not Available

    2013-03-01

    The U.S. Department of Energy-sponsored Transportation Energy Futures (TEF) project examines how combining multiple strategies could reduce both GHG emissions and petroleum use by 80%. The project's primary objective was to help inform domestic decisions about transportation energy strategies, priorities, and investments, with an emphasis on previously underexplored opportunities related to energy efficiency and renewable energy in light-duty vehicles, non-light-duty vehicles, fuels, and transportation demand. This PowerPoint provides an overview of the project and its findings.

  7. Wood residuals find big uses in small pieces

    SciTech Connect (OSTI)

    Glenn, J.

    1996-12-01

    With a history of finding economic uses for leftovers, the wood industry explores sustainable options for creating higher value products. Years ago, companies saw the use - any use - of residues as a sound, economic business practice. Today, many companies are looking to go beyond low value products such as mulch, animal bedding and fuel, and market to higher value end users. Additionally, with so much material from the primary industries already accounted for, consumers of wood residue are in need of additional supply from sources such as secondary mills (furniture manufacturers, etc.), as wells as the C&D and MSW streams. This paper discusses these products and markets.

  8. EA-1378: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: AlternativeCommunication3-E Wholesale Power Rate Schedule Duke-3-E91: Finding ofEnergy

  9. EA-2014: Finding of No Significant Impact | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And StatisticsProgramof Energy12-98SouthDetailedDon0: Public Scoping NoticeBFinding ofFinding

  10. EA-1979: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfinding of no significant impact for

  11. EA-1982: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfinding of no significantcontinuation

  12. EA-1983: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfinding of noadopted an EA prepared

  13. EA-1994: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfinding of noadopted an EAthea Final

  14. EA-1995: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfinding of noadopted an

  15. EA-2002: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfinding ofRight-of-Way Application

  16. EA-2011: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-in electricLaboratoryofNoticesEnergyfindingChromium Plume ControlRelease

  17. Curiosity rover finds evidence of Mars' primitive continental crust

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAuditsClusterInformationContractCorporateCrookerCrystalCuriosity rover finds

  18. Findings of No Significant Impact (FONSI) | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergy A plug-inPPLforLDRD Report to CongressApril 6,Final9Reportjobs can be foundFindings

  19. Neutrons find "missing" magnetism of plutonium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shinesSolar Photovoltaic(MillionNature andNeutrinos fromdouble-betaNeutrons find

  20. Find U.S. Government R&D Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &Reports FindU.S.

  1. Finding Engineering Inspiration at GE | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFES OctoberEvanServices » Incentives &ReportseBooks Find

  2. Community Wind Handbook/Find an Installer | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LISTStar EnergyLawler,Coal TechnologiesClioCommunity Wind Handbook/Find an Installer

  3. Research Finds Vitamin D Deficiency Affects Bone Quality

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMassR&D100 WinnersAffiliates Research Affiliates Yan Mei Wang Yan Mei andResearch Finds

  4. Research Finds Vitamin D Deficiency Affects Bone Quality

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMassR&D100 WinnersAffiliates Research Affiliates Yan Mei Wang Yan MeiResearch Finds

  5. Findings of No Significant Impact (FONSI) | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergyTher i nA Guide to Tapping into Funding for EnergyOctober 8, 2008 EA-1604: Finding

  6. DOE issues Finding of No Significant Impact for the Environmental

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you not find what you were looking for? Try theDOE Progress

  7. DOE issues Finding of No Significant Impact for the Environmental

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you not find what you were looking for? Try theDOE ProgressAssessment on

  8. EA-1183: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91: Final3: Finding of No

  9. EA-1212: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91: Final3: Finding of

  10. EA-1236: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91: Final3: Finding

  11. EA-1301: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91: Final3: Finding262:0:

  12. EA-1426: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91: Final3:38:Finding of No

  13. EA-1499: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding of No Significant

  14. EA-1535: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding of No33:

  15. EA-1570: Final Environmental Assessment and Finding of No Significant

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of2E:\BILLS\H6.PP91:Finding of

  16. EA-1732: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8: Finding8:5:7:9:FinalNext

  17. EA-1740: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding of No

  18. EA-1742: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding of No2:

  19. EA-1744: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding of4:

  20. EA-1745: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding of4:5:

  1. EA-1747: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0: Finding6:7:

  2. EA-1750: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0:Finding of No

  3. EA-1754: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0:Finding3:4:

  4. EA-1756: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe, LA0:Finding3:4:5:6:

  5. EA-1760: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault, MN8:Monroe,: Finding of9:0:

  6. EA-1789: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalin Fairbault,Deliverables |5: Finding of8:9:

  7. EA-1797: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment of Energy 6: Sempra7: Finding

  8. EA-1810: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0: Finding of No

  9. EA-1812: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0: FindingColorado

  10. EA-1814: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0:FinalFinding of

  11. EA-1815: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0:FinalFinding

  12. EA-1816: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0:FinalFinding6:

  13. EA-1818: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartment ofDepartment of0:FinalFinding6:8:

  14. EA-1834: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: Finding of No3:4:

  15. EA-1837: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32: Finding of6:7:

  16. EA-1845: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw, MI |32:FinalFinding of No

  17. EA-1854: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,DepartmentFinalinDepartmentSaginaw,Energy 9:2:4: Finding

  18. EA-1859: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE Notice of Availability andFinalFinding of

  19. EA-1867: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE Notice ofFinal EnvironmentalImpactFinding

  20. EA-1882: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE Notice ofFinal70:Draftof Public2: Finding

  1. EA-1885: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE Notice ofFinal70:DraftofDraftFinalFinding

  2. EA-1887: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE NoticeFinal Environmental7: Finding of No

  3. EA-1897: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE NoticeFinalof EnergyFinalFinding of No

  4. EA-1904: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOE NoticeFinalofDepartment2:DraftFinalFinding

  5. EA-1907: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding of No SignificantFinalFinding of No

  6. EA-1917: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding of No Significant

  7. EA-1935: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5:2:

  8. EA-1937: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFinding ofofFinding5:2:Draft

  9. EA-1942: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFindingDraft EnvironmentalFinalFinding of

  10. EA-1944: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFindingDraft4: Finding of No Significant

  11. EA-1958: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8: DOEFindingDraft4:Final EnvironmentalFinding of

  12. EA-1969: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8:Final Environmental Assessment8:Finding of No

  13. EA-1975: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8:Final EnvironmentalFinalDraftFinding of No

  14. EA-1988: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8:Final78: Sand Creeknautical milesFinding of No

  15. EA-2003: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|Department of Energy 8:Final78: SandDepartment of2: FinalFinalFinding

  16. Find Financing for Energy Efficiency Upgrades | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum12, 2015Executive Order14,EnergyFinancing and Investing in TribalFind

  17. Finding & Sharing Information about Energy Efficiency | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum12, 2015Executive Order14,EnergyFinancing and Investing inEnergy Finding

  18. Research Finds Vitamin D Deficiency Affects Bone Quality

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-RichProtonAboutNuclearPrincipalResearchResearch Finds Vitamin D

  19. Findings of No Significant Impact (FONSI) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuelsof Energy Services » ProgramPolicy andResearchDataDepartmentFindings of No

  20. EA-1985: Finding of No Significant Impact | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:IAbout Us|ofElizabethEnergy85: Finding of No