National Library of Energy BETA

Sample records for distance driven mi

  1. NONPROFIT ORG DETROIT, MI

    E-Print Network [OSTI]

    Berdichevsky, Victor

    NONPROFIT ORG US POSTAGE PAID DETROIT, MI PERMIT NO 3844 College of Engineering Wayne State University 5050 Anthony Wayne Drive Room 1153 · Detroit, MI 48202 Phone (313) 577-3780 · Fax (313) 577, Wayne State University 5050 Anthony Wayne Drive Detroit, MI 48202 My first assignment for Ex

  2. Introduction The median problem for the reversal distance in

    E-Print Network [OSTI]

    Lonardi, Stefano

    genomes E. Ohlebusch, M.I. Abouelhoda, K. Hockel, J. Stallkamp University of Ulm, Germany CPM 2005 The median problem for the reversal distance in circular bacterial genomes #12;Introduction Methods Conclusion General Problem Distances Specific Problem Median Problem Given 3 genomes G1, G2, and G3, find

  3. Real-time sub-<mi>Å>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  4. Package `MiST' July 2, 2014

    E-Print Network [OSTI]

    Brent, Roger

    Package `MiST' July 2, 2014 Type Package Title Mixed effects Score Test for continuous outcomes topics documented: MiST-package 10 1 #12;2 linear.test MiST-package Mixed effects Score Test Description Test for association between

  5. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  6. Proximity-Driven Enhanced Magnetic Order at Ferromagnetic-Insulator–Magnetic-Topological-Insulator Interface

    E-Print Network [OSTI]

    Li, Mingda

    Magnetic exchange driven proximity effect at a magnetic-insulator–topological-insulator (MI-TI) interface provides a rich playground for novel phenomena as well as a way to realize low energy dissipation quantum devices. ...

  7. Southern Asia future plans feature long-distance lines

    SciTech Connect (OSTI)

    Not Available

    1991-11-01

    This paper reports that although pipe line mileage working, planned and under study has dipped slightly from 47,346 km (29,420 mi) to 44,853 km (27,871 mi), Southern Asia continues to hold a strong position for future projects with some of the most interesting programs in the international market. Two dramatic, long-distance natural gas transmission, gathering and lateral networks continue to hold the future pipe line construction spotlight in Southern Asia. The Association of South East Asian Nations (ASEAN) continues to study a 7,830 km (4,865 mi) gas transmission system. With an estimated cost of $10 billion, the system includes some 6,276 km (3,900 mi) of transmission lines, with 1,094 km (680 mi) offshore. Group members include Brunei, Indonesia, Malaysia, the Philippines, Singapore and Thailand. The second project, the Trans-Asian Pipeline System, involves 3,380 km (2,100 mi) of transmission lines from the Iran's Bandar Abbas gas field across Pakistan to a terminal at Calcutta, India.

  8. MI high power operation and future plans

    SciTech Connect (OSTI)

    Kourbanis, Ioanis; /Fermilab

    2008-09-01

    Fermilab's Main Injector on acceleration cycles to 120 GeV has been running a mixed mode operation delivering beam to both the antiproton source for pbar production and to the NuMI[1] target for neutrino production since 2005. On January 2008 the slip stacking process used to increase the beam to the pbar target was expanded to include the beam to the NuMI target increasing both the beam intensity and power. The current high power MI operation will be described along with the near future plans.

  9. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    P. Adamson; K. Anderson; M. Andrews; R. Andrews; I. Anghel; D. Augustine; A. Aurisano; S. Avvakumov; D. S. Ayres; B. Baller; B. Barish; G. Barr; W. L. Barrett; R. H. Bernstein; J. Biggs; M. Bishai; A. Blake; V. Bocean; G. J. Bock; D. J. Boehnlein; D. Bogert; K. Bourkland; S. V. Cao; C. M. Castromonte; S. Childress; B. C. Choudhary; J. A. B. Coelho; J. H. Cobb; L. Corwin; D. Crane; J. P. Cravens; D. Cronin-Hennessy; R. J. Ducar; J. K. de Jong; A. V. Devan; N. E. Devenish; M. V. Diwan; A. R. Erwin; C. O. Escobar; J. J. Evans; E. Falk; G. J. Feldman; T. H. Fields; R. Ford; M. V. Frohne; H. R. Gallagher; V. Garkusha; R. A. Gomes; M. C. Goodman; P. Gouffon; N. Graf; R. Gran; N. Grossman; K. Grzelak; A. Habig; S. R. Hahn; D. Harding; D. Harris; P. G. Harris; J. Hartnell; R. Hatcher; S. Hays; K. Heller; A. Holin; J. Huang; J. Hylen; A. Ibrahim; D. Indurthy; G. M. Irwin; Z. Isvan; D. E. Jaffe; C. James; D. Jensen; J. Johnstone; T. Kafka; S. M. S. Kasahara; G. Koizumi; S. Kopp; M. Kordosky; A. Kreymer; K. Lang; C. Laughton; G. Lefeuvre; J. Ling; P. J. Litchfield; L. Loiacono; P. Lucas; W. A. Mann; A. Marchionni; M. L. Marshak; N. Mayer; C. McGivern; M. M. Medeiros; R. Mehdiyev; J. R. Meier; M. D. Messier; D. G. Michael; R. H. Milburn; J. L. Miller; W. H. Miller; S. R. Mishra; S. Moed Sher; C. D. Moore; J. Morfin; L. Mualem; S. Mufson; S. Murgia; M. Murtagh; J. Musser; D. Naples; J. K. Nelson; H. B. Newman; R. J. Nichol; J. A. Nowak; J. O Connor; W. P. Oliver; M. Olsen; M. Orchanian; S. Osprey; R. B. Pahlka; J. Paley; A. Para; R. B. Patterson; T. Patzak; Z. Pavlovic; G. Pawloski; A. Perch; E. A. Peterson; D. A. Petyt; M. M. Pfutzner; S. Phan-Budd; R. K. Plunkett; N. Poonthottathil; P. Prieto; D. Pushka; X. Qiu; A. Radovic; R. A. Rameika; J. Ratchford; B. Rebel; R. Reilly; C. Rosenfeld; H. A. Rubin; K. Ruddick; M. C. Sanchez; N. Saoulidou; L. Sauer; J. Schneps; D. Schoo; A. Schreckenberger; P. Schreiner; P. Shanahan; R. Sharma; W. Smart; C. Smith; A. Sousa; A. Stefanik; N. Tagg; R. L. Talaga; G. Tassotto; J. Thomas; J. Thompson; M. A. Thomson; X. Tian; A. Timmons; D. Tinsley; S. C. Tognini; R. Toner; D. Torretta; I. Trostin; G. Tzanakos; J. Urheim; P. Vahle; K. Vaziri; E. Villegas; B. Viren; G. Vogel; R. C. Webber; A. Weber; R. C. Webb; A. Wehmann; C. White; L. Whitehead; L. H. Whitehead; S. G. Wojcicki; M. L. Wong-Squires; T. Yang; F. X. Yumiceva; V. Zarucheisky; R. Zwaska

    2015-07-29

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  10. The NuMI Neutrino Beam

    E-Print Network [OSTI]

    Adamson, P; Andrews, M; Andrews, R; Anghel, I; Augustine, D; Aurisano, A; Avvakumov, S; Ayres, D S; Baller, B; Barish, B; Barr, G; Barrett, W L; Bernstein, R H; Biggs, J; Bishai, M; Blake, A; Bocean, V; Bock, G J; Boehnlein, D J; Bogert, D; Bourkland, K; Cao, S V; Castromonte, C M; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Corwin, L; Crane, D; Cravens, J P; Cronin-Hennessy, D; Ducar, R J; de Jong, J K; Devan, A V; Devenish, N E; Diwan, M V; Erwin, A R; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Fields, T H; Ford, R; Frohne, M V; Gallagher, H R; Garkusha, V; Gomes, R A; Goodman, M C; Gouffon, P; Graf, N; Gran, R; Grossman, N; Grzelak, K; Habig, A; Hahn, S R; Harding, D; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Hays, S; Heller, K; Holin, A; Huang, J; Hylen, J; Ibrahim, A; Indurthy, D; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Johnstone, J; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Kreymer, A; Lang, K; Laughton, C; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marchionni, A; Marshak, M L; Mayer, N; McGivern, C; Medeiros, M M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Milburn, R H; Miller, J L; Miller, W H; Mishra, S R; Sher, S Moed; Moore, C D; Morfin, J; Mualem, L; Mufson, S; Murgia, S; Murtagh, M; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Nowak, J A; Connor, J O; Oliver, W P; Olsen, M; Orchanian, M; Osprey, S; Pahlka, R B; Paley, J; Para, A; Patterson, R B; Patzak, T; Pavlovic, Z; Pawloski, G; Perch, A; Peterson, E A; Petyt, D A; Pfutzner, M; Phan-Budd, S; Plunkett, R K; Poonthottathil, N; Prieto, P; Pushka, D; Qiu, X; Radovic, A; Rameika, R A; Ratchford, J; Rebel, B; Reilly, R; Rosenfeld, C; Rubin, H A; Ruddick, K; Sanchez, M C; Saoulidou, N; Sauer, L; Schneps, J; Schoo, D; Schreckenberger, A; Schreiner, P; Shanahan, P; Sharma, R; Smart, W; Smith, C; Sousa, A; Stefanik, A; Tagg, N; Talaga, R L; Tassotto, G; Thomas, J; Thompson, J; Thomson, M A; Tian, X; Timmons, A; Tinsley, D; Tognini, S C; Toner, R; Torretta, D; Trostin, I; Tzanakos, G; Urheim, J; Vahle, P; Vaziri, K; Villegas, E; Viren, B; Vogel, G; Webber, R C; Weber, A; Webb, R C; Wehmann, A; White, C; Whitehead, L; Whitehead, L H; Wojcicki, S G; Wong-Squires, M L; Yang, T; Yumiceva, F X; Zarucheisky, V; Zwaska, R

    2015-01-01

    This paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important design details of individual components are described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  11. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  12. MI Gap Clearing Kicker Magnet Design Review

    SciTech Connect (OSTI)

    Jensen, Chris; /Fermilab

    2008-10-01

    The kicker system requirements were originally conceived for the NOvA project. NOvA is a neutrino experiment located in Minnesota. To achieve the desired neutrino flux several upgrades are required to the accelerator complex. The Recycler will be used as a proton pre-injector for the Main Injector (MI). As the Recycler is the same size as the MI, it is possible to do a single turn fill ({approx}11 {micro}sec), minimizing the proton injection time in the MI cycle and maximizing the protons on target. The Recycler can then be filled with beam while the MI is ramping to extract beam to the target. To do this requires two new transfer lines. The existing Recycler injection line was designed for 10{pi} pbar beams, not the 20{pi} proton beams we anticipate from the Booster. The existing Recycler extraction line allows for proton injection through the MI, while we want direct injection from the Booster. These two lines will be decommissioned. The new injection line from the MI8 line into the Recycler will start at 848 and end with injection kickers at RR104. The new extraction line in the RR30 straight section will start with a new extraction kicker at RR232 and end with new MI injection kickers at MI308. Finally, to reduce beam loss activation in the enclosure, a new gap clearing kicker will be used to extract uncaptured beam created during the slip stack injection process down the existing dump line. It was suggested that the MI could benefit from this type of system immediately. This led to the early installation of the gap clearing system in the MI, followed by moving the system to Recycler during NOvA. The specifications also changed during this process. Initially the rise and fall time requirements were 38 ns and the field stability was {+-}1%. The 38 ns is based on having a gap of 2 RF buckets between injections. (There are 84 RF buckets that can be filled from the Booster for each injection, but 82 would be filled with beam. MI and Recycler contain 588 RF buckets.) A rough cost/benefit analysis showed that increasing the number of empty buckets to 3 decreased the kicker system cost by {approx}30%. This could be done while not extending the running time since this is only a 1% reduction in protons per pulse, hence the rise and fall time are now 57 ns. Additionally, the {+-}1% tolerance would have required a fast correction kicker while {+-}3% could be achieved without this kicker. The loosened tolerance was based on experience on wide band damping systems in the MI. A higher power wideband damping system is a better use of the resources as it can be used to correct for multiple sources of emittance growth. Finally, with the use of this system for MI instead of Recycler, the required strength grew from 1.2 mrad to 1.7 mrad. The final requirements for this kicker are listed.

  13. Sequence determinants of pri-miRNA processing

    E-Print Network [OSTI]

    Auyeung, Vincent C. (Vincent Churk-man)

    2012-01-01

    MicroRNAs (miRNAs) are short RNAs that regulate many processes in physiology and pathology by guiding the repression of target messenger RNAs. For classification purposes, miRNAs are defined as ~22 nt RNAs that are produced ...

  14. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Henry, Jon C. [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States)] [Department of Surgery, Ohio State University, Columbus, OH 43210 (United States); Jiang, Jinmai [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)] [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States); Esau, Christine [Regulus Therapeutics, Carlsbad, CA (United States)] [Regulus Therapeutics, Carlsbad, CA (United States); Gusev, Yuriy [Lombardi Cancer Center, Georgetown University, Washington, DC (United States)] [Lombardi Cancer Center, Georgetown University, Washington, DC (United States); Lerner, Megan R. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Postier, Russell G. [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)] [Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Brackett, Daniel J. [Veterans Affairs Medical Center, Oklahoma City, OK (United States)] [Veterans Affairs Medical Center, Oklahoma City, OK (United States); Schmittgen, Thomas D., E-mail: Schmittgen.2@osu.edu [College of Pharmacy, Ohio State University, Columbus, OH 43210 (United States)

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  15. “Nodal Gap” Induced by the Incommensurate Diagonal Spin Density Modulation in Underdoped High- <mi>Tmi>c> Superconductors

    SciTech Connect (OSTI)

    Zhou, Tao [Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Gao, Yi [Nanjing Normal University, Nanjing 210023, China; Zhu, Jian-Xin [Los Alamos National Laboratory, Los Alamos, NM 87545, USA

    2015-01-01

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the<mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the<mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  16. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation.

    E-Print Network [OSTI]

    Wu, Jian; Zern, M A

    2010-01-01

    Liver ?brosis causes downregulation of miRNA-150 and miRNA-and their overexpression causes decreased stellate cellJ, Zern MA. Liver ?brosis causes downregulation of miRNA-150

  17. Analytical Study of Hexapod miRNAs using Phylogenetic Methods

    E-Print Network [OSTI]

    Mishra, A K

    2012-01-01

    MicroRNAs (miRNAs) are a class of non-coding RNAs that regulate gene expression. Identification of total number of miRNAs even in completely sequenced organisms is still an open problem. However, researchers have been using techniques that can predict limited number of miRNA in an organism. In this paper, we have used homology based approach for comparative analysis of miRNA of hexapoda group .We have used Apis mellifera, Bombyx mori, Anopholes gambiae and Drosophila melanogaster miRNA datasets from miRBase repository. We have done pair wise as well as multiple alignments for the available miRNAs in the repository to identify and analyse conserved regions among related species. Unfortunately, to the best of our knowledge, miRNA related literature does not provide in depth analysis of hexapods. We have made an attempt to derive the commonality among the miRNAs and to identify the conserved regions which are still not available in miRNA repositories. The results are good approximation with a small number of mis...

  18. Simulations of neutron multiplicity measurements with MCNP-PoliMi.

    SciTech Connect (OSTI)

    Mattingly, John K.; Pozzi, Sara A. (University of Michigan); Clarke, Shaun D. (University of Michigan); Dennis, Ben D. (University of Michigan); Miller, Eric C.

    2010-09-01

    The heightened focus on nuclear safeguards and accountability has increased the need to develop and verify simulation tools for modeling these applications. The ability to accurately simulate safeguards techniques, such as neutron multiplicity counting, aids in the design and development of future systems. This work focuses on validating the ability of the Monte Carlo code MCNPX-PoliMi to reproduce measured neutron multiplicity results for a highly multiplicative sample. The benchmark experiment for this validation consists of a 4.5-kg sphere of plutonium metal that was moderated by various thicknesses of polyethylene. The detector system was the nPod, which contains a bank of 15 3He detectors. Simulations of the experiments were compared to the actual measurements and several sources of potential bias in the simulation were evaluated. The analysis included the effects of detector dead time, source-detector distance, density, and adjustments made to the value of {nu}-bar in the data libraries. Based on this analysis it was observed that a 1.14% decrease in the evaluated value of {nu}-bar for 239Pu in the ENDF-VII library substantially improved the accuracy of the simulation.

  19. BMPs Regulate the Oft Development via miRNAs 

    E-Print Network [OSTI]

    Bai, Yan

    2014-08-04

    c-Jun N-terminal Kinase LAP Latency Associated Peptide LLC Large Latent Complex LTBP Latent Tgf-? Binding Protein MFS Marfan Syndrome mi...

  20. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  1. The Sequential Action of miR156 and miR172 Regulates Developmental Timing

    E-Print Network [OSTI]

    Weigel, Detlef

    Planck Institute for Developmental Biology, D-72076 Tu¨ bingen, Germany *Correspondence: spoethig@sas elegans (Moss, 2007; Rougvie, 2005) and plants (Ba¨ urle and Dean, 2006; Chuck and Hake, 2005; Poethig in Moss, 2007; Pasquinelli and Ruvkun, 2002; Rougvie, 2005). These were the first miRNAs to be discovered

  2. Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

    E-Print Network [OSTI]

    Choi, Philip S.

    MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different neuronal populations is still largely unknown. We report that miRNAs ...

  3. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the miR-200c/141 CpG island is closely linked to their inappropriate silencing in cancer cells. Since the miR-200c cluster plays a significant role in EMT, our results suggest an important role for DNA methylation in the control of phenotypic conversions in normal cells.

  4. Distance-based accessibility indices

    E-Print Network [OSTI]

    Csató, László

    2015-01-01

    The paper attempts to develop a suitable accessibility index for networks where each link has a value such that a smaller number is preferred like distance, cost, or travel time. A measure called distance sum is characterized by three independent properties: anonymity, an appropriately chosen independence axiom, and dominance preservation, which requires that a node not far to any other is at least as accessible. We argue for the need of eliminating the independence property in certain applications. Therefore generalized distance sum, a family of accessibility indices, will be suggested. It is linear, considers the accessibility of vertices besides their distances and depends on a parameter in order to control its deviation from distance sum. Generalized distance sum is anonymous and satisfies dominance preservation if its parameter meets a sufficient condition. Two detailed examples demonstrate its ability to reflect the vulnerability of accessibility to link disruptions.

  5. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: • Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. • The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. • Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  6. Proximity-driven enhanced magnetic order at ferromagnetic-insulator-magnetic-topological-insulator interface

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Mingda; Zhu, Yimei; Chang, Cui -Zu; Kirby, B. J.; Jamer, Michelle E.; Cui, Wenping; Wu, Lijun; Wei, Peng; Heiman, Don; Li, Ju; et al

    2015-08-17

    Magnetic exchange driven proximity effect at a magnetic-insulator–topological-insulator (MI-TI) interface provides a rich playground for novel phenomena as well as a way to realize low energy dissipation quantum devices. In this study, we report a dramatic enhancement of proximity exchange coupling in the MI/magnetic-TI EuS/Sb2–xVxTe3 hybrid heterostructure, where V doping is used to drive the TI (Sb2Te3) magnetic. We observe an artificial antiferromagneticlike structure near the MI-TI interface, which may account for the enhanced proximity coupling. The interplay between the proximity effect and doping in a hybrid heterostructure provides insights into the engineering of magnetic ordering.

  7. miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice Cyrielle-regulated kinase-5 (ERK5) activity. We show here that ERK5 is a miR-143 target in prostate cancer. Conclusions: mi, Apparailly F, Fernandez PL, et al. (2009) miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate

  8. An Energy-Driven Approach to Linkage Unfolding Jason H. Cantarella

    E-Print Network [OSTI]

    Demaine, Erik

    An Energy-Driven Approach to Linkage Unfolding Jason H. Cantarella Erik D. Demaine Hayley N. Iben in the original linkage and expanding all distances between pairs of vertices. The alternative approach of [4 these snapshots remains opaque. 2 Our Results. In this paper, we introduce a new energy-driven approach

  9. National Wind Distance Learning Collaborative

    SciTech Connect (OSTI)

    Dr. James B. Beddow

    2013-03-29

    Executive Summary The energy development assumptions identified in the Department of Energy's position paper, 20% Wind Energy by 2030, projected an exploding demand for wind energy-related workforce development. These primary assumptions drove a secondary set of assumptions that early stage wind industry workforce development and training paradigms would need to undergo significant change if the workforce needs were to be met. The current training practice and culture within the wind industry is driven by a relatively small number of experts with deep field experience and knowledge. The current training methodology is dominated by face-to-face, classroom based, instructor present training. Given these assumptions and learning paradigms, the purpose of the National Wind Distance Learning Collaborative was to determine the feasibility of developing online learning strategies and products focused on training wind technicians. The initial project scope centered on (1) identifying resources that would be needed for development of subject matter and course design/delivery strategies for industry-based (non-academic) training, and (2) development of an appropriate Learning Management System (LMS). As the project unfolded, the initial scope was expanded to include development of learning products and the addition of an academic-based training partner. The core partners included two training entities, industry-based Airstreams Renewables and academic-based Lake Area Technical Institute. A third partner, Vision Video Interactive, Inc. provided technology-based learning platforms (hardware and software). The revised scope yielded an expanded set of results beyond the initial expectation. Eight learning modules were developed for the industry-based Electrical Safety course. These modules were subsequently redesigned and repurposed for test application in an academic setting. Software and hardware developments during the project's timeframe enabled redesign providing for student access through the use of tablet devices such as iPads. Early prototype Learning Management Systems (LMS) featuring more student-centric access and interfaces with emerging social media were developed and utilized during the testing applications. The project also produced soft results involving cross learning between and among the partners regarding subject matter expertise, online learning pedagogy, and eLearning technology-based platforms. The partners believe that the most significant, overarching accomplishment of the project was the development and implementation of goals, activities, and outcomes that significantly exceeded those proposed in the initial grant application submitted in 2009. Key specific accomplishments include: (1) development of a set of 8 online learning modules addressing electrical safety as it relates to the work of wind technicians; (3) development of a flexible, open-ended Learning Management System (LMS): (3) creation of a robust body of learning (knowledge, experience, skills, and relationships). Project leaders have concluded that there is substantial resource equity that could be leverage and recommend that it be carried forward to pursue a Next Stage Opportunity relating to development of an online core curriculum for institute and community college energy workforce development programs.

  10. NuMI Target Station AHIPA09 10/19/09

    E-Print Network [OSTI]

    McDonald, Kirk

    MI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 11Remote 5-axis lift table Numi target+baffle on liftNuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 1 Target Station Infrastructure: The Nu slide overview of NuMI #12;NuMI Target Station AHIPA09 10/19/09 Jim Hylen/FNAL Page 2 NuMI produces

  11. Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

    E-Print Network [OSTI]

    Edbauer, Dieter

    MicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions as translational repressor. We show that ...

  12. Efficient long distance quantum communication

    E-Print Network [OSTI]

    Sreraman Muralidharan; Linshu Li; Jungsang Kim; Norbert Lütkenhaus; Mikhail D. Lukin; Liang Jiang

    2015-09-28

    Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (>1000km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters, as a promising approach, can overcome both photon loss and operation errors, and hence significantly speedup the communication rate. Depending on the methods used to correct loss and operation errors, all the proposed QR schemes can be classified into three categories (generations). Here we present the first systematic comparison of three generations of quantum repeaters by evaluating the cost of both temporal and physical resources, and identify the optimized quantum repeater architecture for a given set of experimental parameters. Our work provides a roadmap for the experimental realizations of highly efficient quantum networks over transcontinental distances.

  13. Long working distance interference microscope

    DOE Patents [OSTI]

    Sinclair, Michael B.; DeBoer, Maarten P.; Smith, Norman F.

    2004-04-13

    Disclosed is a long working distance interference microscope suitable for three-dimensional imaging and metrology of MEMS devices and test structures on a standard microelectronics probe station. The long working distance of 10-30 mm allows standard probes or probe cards to be used. This enables nanometer-scale 3-D height profiles of MEMS test structures to be acquired across an entire wafer. A well-matched pair of reference/sample objectives is not required, significantly reducing the cost of this microscope, as compared to a Linnik microinterferometer.

  14. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xi’an 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: •We detected expression of miR-205 in breast cancer cell lines and tissue samples. •We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. •We suggest the lower expression of miR-205 play a role in breast cancer onset. •These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  15. miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

    E-Print Network [OSTI]

    Mellios, Nikolaos

    Using quantitative analyses, we identified microRNAs (miRNAs) that were abundantly expressed in visual cortex and that responded to dark rearing and/or monocular deprivation. The most substantially altered miRNA, miR-132, ...

  16. Molecular Cell Loss of miR-200 Inhibition of Suz12 Leads to

    E-Print Network [OSTI]

    In an inducible oncogenesis model, the miR-200 family is inhibited during CSC formation but not trans- formation

  17. Discovery of miRNA-regulated processes in mammalian development

    E-Print Network [OSTI]

    Young, Amanda Garfinkel

    2010-01-01

    The genomes of plants and animals encode hundreds of non-coding ~22nt RNAs termed "microRNAs" (miRNAs). These RNAs guide the sequence-specific inhibition of translation and destabilization of mRNA targets through short ...

  18. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  19. Distance Probes of Dark Energy

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Kim, A. G.; Padmanabhan, N.; Aldering, G.; Allen, S. W.; Baltay, C.; Cahn, R. N.; D' Andrea, C. B.; Dalal, N.; Dawson, K. S.; Denney, K. D.; et al

    2015-03-15

    We present the results from the Distances subgroup of the Cosmic Frontier Community Planning Study (Snowmass 2013). This document summarizes the current state of the field as well as future prospects and challenges. In addition to the established probes using Type Ia supernovae and baryon acoustic oscillations, we also consider prospective methods based on clusters, active galactic nuclei, gravitational wave sirens and strong lensing time delays.

  20. Model-Driven Risk Analysis

    E-Print Network [OSTI]

    Stølen, Ketil

    1 123 Model-Driven Risk Analysis The CORAS Approach | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | >springer.com ISBN 978-3-642-12322-1 Model-DrivenRiskAnalysis Mass Soldal Lund Bjørnar Solhaug Ketil Stølen Lund·Solhaug Stølen Lund · Solhaug · Stølen Model-Driven Risk Analysis The term"risk"is known from many

  1. The driven oscillator

    E-Print Network [OSTI]

    T. B. Smith

    2015-08-10

    Using the Wigner-Weyl mapping of quantum mechanics to phase space we consider exactly the quantum mechanics of an harmonic oscillator driven by an external white noise force or whose frequency is time dependent, either adiabatically or parametrically. We find several transition probabilities exactly. We also consider the (quantum mechanical) randomizing effects of the external white noise force on the Weyl quantized phase angle and upon other Weyl quantized quantities.

  2. Metrics and methods for social distance

    E-Print Network [OSTI]

    Andris, Clio

    2011-01-01

    Distance measures are important for scientists because they illustrate the dynamics of geospatial topologies for physical and social processes. Two major types of distance are generally used for this purpose: Euclidean ...

  3. miR-153 and miR-335, Ethanol Sensitive MicroRNAs, Control NSC/NPC Maturation during Fetal Brain Development 

    E-Print Network [OSTI]

    Tsai, Pai Chi

    2014-05-05

    conclude that miR-335 and miR-153 act as molecular brakes to prevent NSCs/NPCs early maturation by regulating cell differentiation genes during the second trimester, and ethanol leads to organizational defects in the developing cerebral cortex through...

  4. Science-Driven Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque| StanfordOffice of Science (SC)Science-Driven Network

  5. ON PULSAR DISTANCE MEASUREMENTS AND THEIR UNCERTAINTIES

    SciTech Connect (OSTI)

    Verbiest, J. P. W.; Lee, K. J. [Max-Planck-Institut fuer Radioastronomie, Auf dem Huegel 69, 53121 Bonn (Germany); Weisberg, J. M.; Chael, A. A. [Department of Physics and Astronomy, Carleton College, Northfield, MN 55057 (United States); Lorimer, D. R. [Department of Physics, West Virginia University, Morgantown, WV 26506 (United States)

    2012-08-10

    Accurate distances to pulsars can be used for a variety of studies of the Galaxy and its electron content. However, most distance measures to pulsars have been derived from the absorption (or lack thereof) of pulsar emission by Galactic H I gas, which typically implies that only upper or lower limits on the pulsar distance are available. We present a critical analysis of all measured H I distance limits to pulsars and other neutron stars, and translate these limits into actual distance estimates through a likelihood analysis that simultaneously corrects for statistical biases. We also apply this analysis to parallax measurements of pulsars in order to obtain accurate distance estimates and find that the parallax and H I distance measurements are biased in different ways, because of differences in the sampled populations. Parallax measurements typically underestimate a pulsar's distance because of the limited distance to which this technique works and the consequential strong effect of the Galactic pulsar distribution (i.e., the original Lutz-Kelker bias), in H I distance limits, however, the luminosity bias dominates the Lutz-Kelker effect, leading to overestimated distances because the bright pulsars on which this technique is applicable are more likely to be nearby given their brightness.

  6. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  7. Thermal noise driven computing

    E-Print Network [OSTI]

    Laszlo B. Kish

    2006-10-28

    The possibility of a new type of computing, where thermal noise is the information carrier and the clock in a computer, is studied. The information channel capacity and the lower limit of energy requirement/dissipation are studied in a simple digital system with zero threshold voltage, for the case of error probability close to 0.5, when the thermal noise is equal to or greater than the digital signal. In a simple hypothetical realization of a thermal noise driven gate, the lower limit of energy needed to generate the digital signal is 1.1*kT/bit. The arrangement has potentially improved energy efficiency and it is free of leakage current, crosstalk and ground plane electromagnetic interference problems. Disadvantage is the large number of redundancy elements needed for low-error operation.

  8. Muscle-driven nanogenerators

    DOE Patents [OSTI]

    Wang, Zhong L. (Marietta, GA); Yang, Rusen (Atlanta, GA)

    2011-03-01

    In a method of generating electricity, a plurality of living cells are grown on an array of piezoelectric nanowires so that the cells engage the piezoelectric nanowires. Induced static potentials are extracted from at least one of the piezoelectric nanowires when at least one of the cells deforms the at least one of the piezoelectric nanowires. A cell-driven electrical generator that includes a substrate and a plurality of spaced-apart piezoelectric nanowires disposed on the substrate. A plurality of spaced-apart conductive electrodes interact with the plurality of piezoelectric nanowires. A biological buffer layer that is configured to promote growth of cells is disposed on the substrate so that cells placed on the substrate will grow and engage the piezoelectric nanowires.

  9. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  10. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co - OHStar Cutter Corp - MI 15 FUSRAP

  11. DOE - Office of Legacy Management -- Westinghouse Naval Ordnance - MI 02

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI 02 FUSRAP

  12. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and Myers Co -VANaval Ordnance - MI

  13. REC Silicon formerly ASiMI | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/Water Use/NevadaaTools < RAPID79.14Silicon formerly ASiMI

  14. MHK Technologies/Mi2 | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource HistoryScenarios Towards 2050Enermar < MHKHydro HelixLangleeMi2 < MHK

  15. From Proceedings of the 12th Annual DIMACS Workshop on Computational Geometry, November 2002. An Energy-Driven Approach to Linkage Unfolding

    E-Print Network [OSTI]

    O'Brien, James F.

    . An Energy-Driven Approach to Linkage Unfolding Jason H. Cantarella Erik D. Demaine Hayley N. Iben James F. O and expanding all distances between pairs of vertices. The alternative approach of [4] leads to a more opaque. 2 Our Results. In this paper, we introduce a new energy-driven approach to straightening arcs

  16. Evaluation of the role of location and distance in recruitment in respondent-driven sampling

    E-Print Network [OSTI]

    McCreesh, Nicky; Johnston, Lisa G; Copas, Andrew; Sonnenberg, Pam; Seeley, Janet; Hayes, Richard J; Frost, Simon DW; White, Richard G

    2011-10-18

    that little or no recruitment occurred in cer- tain parts of the target study areas [7-9]. Despite this, to our knowledge no other RDS studies have looked in detail at how the locations of recruits’ residencies affected recruitment, perhaps due... potentially reduce this problem. Our study was carried out in a rural area where the majority of people work as farmers. This is in contrast to many RDS studies which are carried out in towns or cities. In these settings, travel times using available transport...

  17. Laser Driven Dynamic Loading of Condensed Matter

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laser Driven Dynamic Loading of Condensed Matter Laser Driven Dynamic Loading of Condensed Matter Advanced diagnostics of experiments covering many orders of magnitude in strain...

  18. Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

    E-Print Network [OSTI]

    Bandyopadhyay, Sarmistha

    Background.?Chronic hepatitis C virus (HCV)–induced liver fibrosis involves upregulation of transforming growth factor (TGF)–? and subsequent hepatic stellate cell (HSC) activation. MicroRNAs (miRNAs) regulate HCV infection ...

  19. Fluid driven reciprocating apparatus

    DOE Patents [OSTI]

    Whitehead, J.C.

    1997-04-01

    An apparatus is described comprising a pair of fluid driven pump assemblies in a back-to-back configuration to yield a bi-directional pump. Each of the pump assemblies includes a piston or diaphragm which divides a chamber therein to define a power section and a pumping section. An intake-exhaust valve is connected to each of the power sections of the pump chambers, and function to direct fluid, such as compressed air, into the power section and exhaust fluid therefrom. At least one of the pistons or diaphragms is connected by a rod assembly which is constructed to define a signal valve, whereby the intake-exhaust valve of one pump assembly is controlled by the position or location of the piston or diaphragm in the other pump assembly through the operation of the rod assembly signal valve. Each of the pumping sections of the pump assemblies are provided with intake and exhaust valves to enable filling of the pumping section with fluid and discharging fluid therefrom when a desired pressure has been reached. 13 figs.

  20. Fluid driven recipricating apparatus

    DOE Patents [OSTI]

    Whitehead, John C. (Davis, CA)

    1997-01-01

    An apparatus comprising a pair of fluid driven pump assemblies in a back-to-back configuration to yield a bi-directional pump. Each of the pump assemblies includes a piston or diaphragm which divides a chamber therein to define a power section and a pumping section. An intake-exhaust valve is connected to each of the power sections of the pump chambers, and function to direct fluid, such as compressed air, into the power section and exhaust fluid therefrom. At least one of the pistons or diaphragms is connected by a rod assembly which is constructed to define a signal valve, whereby the intake-exhaust valve of one pump assembly is controlled by the position or location of the piston or diaphragm in the other pump assembly through the operation of the rod assembly signal valve. Each of the pumping sections of the pump assemblies are provided with intake and exhaust valves to enable filling of the pumping section with fluid and discharging fluid therefrom when a desired pressure has been reached.

  1. Global identification of miRNAs and targets in Populus euphratica under salt stress

    E-Print Network [OSTI]

    Deng, Xing-Wang

    Global identification of miRNAs and targets in Populus euphratica under salt stress Bosheng Li, a typical hydro-halophyte, is ideal for studying salt stress responses in woody plants. MicroRNAs (miRNA may regulate tolerance to salt stress but this has not been widely studied in P. euphratica

  2. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

    E-Print Network [OSTI]

    Ji, Qing; Hao, Xinbao; Meng, Yang; Zhang, Min; DeSano, Jeffrey; Fan, Daiming; Xu, Liang

    2008-09-21

    Background: MicroRNAs (miRNAs), some of which function as oncogenes or tumor suppressor genes, are involved in carcinogenesis via regulating cell proliferation and/or cell death. MicroRNA miR-34 was recently found to be a direct target of p53...

  3. Formation distance Stphanie Jean-Daubias

    E-Print Network [OSTI]

    Jean-Daubias, Stéphanie

    ) dans le temps et dans l'espace de l'apprenant et de l'équipe professorale 3 #12;Deux types de médias en;Formation à distance et espace Plusieurs variantes possibles enseignement entièrement à distance

  4. Distance Education Graduate Program in Environmental Science

    E-Print Network [OSTI]

    Ma, Lena

    Distance Education Graduate Program in Environmental Science Soil & Water ScienceSoil & Water (Environmental Science Track). Courses are offered via distance education to accommodate place-bound students and educational opportunities for students seeking careers in soil and water science in land and water resource

  5. Short distance physics with heavy quark potentials

    E-Print Network [OSTI]

    Zantow, F; Karsch, Frithjof; Petreczky, P

    2002-01-01

    We present lattice studies of heavy quark potentials in the quenched approximation of QCD at finite temperatures. Both, the color singlet and color averaged potentials are calculated. While the potentials are well known at large distances, we give a detailed analysis of their short distance behavior (from 0.015 fm to 1 fm) near the critical temperature. At these distances we expect that the T-dependent potentials go over into the zero temperature potential. Indeed, we find evidences that the temperature influence gets suppressed and the potentials starts to become a unique function of the underlying distance scale. We use this feature to normalize the heavy quark potentials at short distances and extract the free energy of the quark system in a gluonic heat bath.

  6. Driven active and passive nematics

    E-Print Network [OSTI]

    Sumesh P. Thampi; Ramin Golestanian; Julia M. Yeomans

    2015-04-25

    We investigate similarities in the micro-structural dynamics between externally driven and actively driven nematics. Walls, lines of strong deformations in the director field, and topological defects are characteristic features of an active nematic. Similar structures form in driven passive nematics when there are inhomogeneities in imposed velocity gradients due to non-linear flow fields or geometrical constraints. Specifically, pressure driven flow of a tumbling passive nematic in an expanding-contracting channel produces walls and defects similar to those seen in active nematics. We also study the response of active nematics to external driving, confirming that imposed shear suppresses the hydrodynamic instabilities. We show that shear fields can lead to wall alignments and the localisation of active turbulence.

  7. Salinity driven oceanographic upwelling

    DOE Patents [OSTI]

    Johnson, David H. (Lakewood, CO)

    1986-01-01

    The salinity driven oceanographic upwelling is maintained in a mariculture device that includes a long main duct in the general shape of a cylinder having perforated cover plates at each end. The mariculture device is suspended vertically in the ocean such that one end of the main duct is in surface water and the other end in relatively deep water that is cold, nutrient rich and relatively fresh in comparison to the surface water which is relatively warm, relatively nutrient deficient and relatively saline. A plurality of elongated flow segregating tubes are disposed in the main duct and extend from the upper cover plate beyond the lower cover plate into a lower manifold plate. The lower manifold plate is spaced from the lower cover plate to define a deep water fluid flow path to the interior space of the main duct. Spacer tubes extend from the upper cover plate and communicate with the interior space of the main duct. The spacer tubes are received in an upper manifold plate spaced from the upper cover plate to define a surface water fluid flow path into the flow segregating tubes. A surface water-deep water counterflow is thus established with deep water flowing upwardly through the main duct interior for discharge beyond the upper manifold plate while surface water flows downwardly through the flow segregating tubes for discharge below the lower manifold plate. During such counterflow heat is transferred from the downflowing warm water to the upflowing cold water. The flow is maintained by the difference in density between the deep water and the surface water due to their differences in salinity. The upwelling of nutrient rich deep water is used for marifarming by fertilizing the nutrient deficient surface water.

  8. Salinity driven oceanographic upwelling

    DOE Patents [OSTI]

    Johnson, D.H.

    1984-08-30

    The salinity driven oceanographic upwelling is maintained in a mariculture device that includes a long main duct in the general shape of a cylinder having perforated cover plates at each end. The mariculture device is suspended vertically in the ocean such that one end of the main duct is in surface water and the other end in relatively deep water that is cold, nutrient rich and relatively fresh in comparison to the surface water which is relatively warm, relatively nutrient deficient and relatively saline. A plurality of elongated flow segregating tubes are disposed in the main duct and extend from the upper cover plate beyond the lower cover plate into a lower manifold plate. The lower manifold plate is spaced from the lower cover plate to define a deep water fluid flow path to the interior space of the main duct. Spacer tubes extend from the upper cover plate and communicate with the interior space of the main duct. The spacer tubes are received in an upper manifold plate spaced from the upper cover plate to define a surface water fluid flow path into the flow segregating tubes. A surface water-deep water counterflow is thus established with deep water flowing upwardly through the main duct interior for discharge beyond the upper manifold plate while surface water flows downwardly through the flow segregating tubes for discharge below the lower manifold plate. During such counterflow heat is transferred from the downflowing warm water to the upflowing cold water. The flow is maintained by the difference in density between the deep water and the surface water due to their differences in salinity. The upwelling of nutrient rich deep water is used for marifarming by fertilizing the nutrient deficient surface water. 1 fig.

  9. Mi2beta Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice

    E-Print Network [OSTI]

    Costa, Flá via C.; Fedosyuk, Halyna; Chazelle, Allen M.; Neades, Renee Y.; Peterson, Kenneth R.

    2012-12-20

    Mi2b Is Required for c-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in b-YAC Transgenic Mice Fla´via C. Costa1¤, Halyna Fedosyuk1, Allen M. Chazelle1, Renee Y. Neades1, Kenneth R. Peterson1,2* 1Department... hemoglobin. A GATA-1-FOG-1-Mi2 repressor complex was recently demonstrated to be recruited to the 2566 GATA motif of the Ac-globin gene. We show that Mi2b is essential for c-globin gene silencing using Mi2b conditional knockout b-YAC transgenic mice...

  10. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 18–24 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: • Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. • The molecular mechanisms regulating miR-128 expression are elucidated. • Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  11. Case study: copyright issues in distance education 

    E-Print Network [OSTI]

    Huddleston, Michael B

    2006-10-30

    Over the years, much attention has been given to copyright law in literature and as it pertains to textbooks and other original academic works. However, as the focus is narrowed to the copyright law as it relates to distance ...

  12. MiR-150, A Novel and Potent Regulator for MLL-AF9 Leukemic Stem Cells 

    E-Print Network [OSTI]

    Cheruku, Patali

    2013-02-18

    Designing the miR-150 sponge primer set .................................................................. 10 Preparation of the DNA fragment containing the miR-150 sponge sequence ............ 10 Construction of pcDNA5-CMV-d2eGFP-miR150sp... protocol. Enzymatic digestion with XhoI and ApaI confirmed the insertion of the miR-150 sponge fragment. The miR-150sp-eGFP sequence (Figure 1) was then amplified using polymerase chain reaction (PCR) with the BamHI forward and SalI reverse primers, gel...

  13. Data-driven batch schuduling

    SciTech Connect (OSTI)

    Bent, John [Los Alamos National Laboratory; Denehy, Tim [GOOGLE; Arpaci - Dusseau, Remzi [UNIV OF WISCONSIN; Livny, Miron [UNIV OF WISCONSIN; Arpaci - Dusseau, Andrea C [NON LANL

    2009-01-01

    In this paper, we develop data-driven strategies for batch computing schedulers. Current CPU-centric batch schedulers ignore the data needs within workloads and execute them by linking them transparently and directly to their needed data. When scheduled on remote computational resources, this elegant solution of direct data access can incur an order of magnitude performance penalty for data-intensive workloads. Adding data-awareness to batch schedulers allows a careful coordination of data and CPU allocation thereby reducing the cost of remote execution. We offer here new techniques by which batch schedulers can become data-driven. Such systems can use our analytical predictive models to select one of the four data-driven scheduling policies that we have created. Through simulation, we demonstrate the accuracy of our predictive models and show how they can reduce time to completion for some workloads by as much as 80%.

  14. Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2

    E-Print Network [OSTI]

    Waterloo, University of

    Computer-Generated Papercutting Jie Xu1 Craig S. Kaplan1 Xiaofeng Mi2 1Computer Graphics Lab David Pattern #12;Related Work Kaplan and Salesin, TOG 2004 Kaplan, GI 2005 #12;Geometric Patterns Geometric

  15. Modulation of Ago-miRNA regulatory networks by cis-sequence elements and target competition

    E-Print Network [OSTI]

    Bosson, Andrew D. (Andrew David)

    2014-01-01

    regulators of gene expression in a wide range of organisms and biological processes. Each miRNA guides Argonaute (Ago) protein complexes to target and repress hundreds of genes in a sequence-dependent manner. To identify ...

  16. Solar Flare Measurements with STIX and MiSolFA

    E-Print Network [OSTI]

    Casadei, Diego

    2014-01-01

    Solar flares are the most powerful events in the solar system and the brightest sources of X-rays, often associated with emission of particles reaching the Earth and causing geomagnetic storms, giving problems to communication, airplanes and even black-outs. X-rays emitted by accelerated electrons are the most direct probe of solar flare phenomena. The Micro Solar-Flare Apparatus (MiSolFA) is a proposed compact X-ray detector which will address the two biggest issues in solar flare modeling. Dynamic range limitations prevent simultaneous spectroscopy with a single instrument of all X-ray emitting regions of a flare. In addition, most X-ray observations so far are inconsistent with the high anisotropy predicted by the models usually adopted for solar flares. Operated at the same time as the STIX instrument of the ESA Solar Orbiter mission, at the next solar maximum (2020), they will have the unique opportunity to look at the same flare from two different directions: Solar Orbiter gets very close to the Sun wit...

  17. Laser driven compact ion accelerator

    DOE Patents [OSTI]

    Tajima, Toshiki

    2005-03-15

    A laser driven compact ion source including a light source that produces an energy pulse, a light source guide that guides the energy pulse to a target and produces an ion beam. The ion beam is transported to a desired destination.

  18. Synchrotron-driven spallation sources

    E-Print Network [OSTI]

    Bryant, P J

    1996-01-01

    The use of synchrotrons for pulsed neutron spallation sources is an example of scientific and technological spin-off from the accelerator development for particle physics. Accelerator-driven sources provide an alternative to the continuous-flux, nuclear reactors that currently furnish the majority of neutrons for research and development. Although the present demand for neutrons can be adequately met by the existing reactors, this situation is unlikely to continue due to the increasing severity of safety regulations and the declared policies of many countries to close down their reactors within the next decade or so. Since the demand for neutrons as a research tool is, in any case,expected to grow, there has been a corresponding interest in sources that are synchrotron-driven or linac-driven with a pulse compression ring and currently several design studies are being made. These accelerator-driven sources also have the advantage of a time structure with a high peak neutron flux. The basic requirement is for a...

  19. Policy driven development : SOA evolvability through late binding

    E-Print Network [OSTI]

    Demchak, Barry

    2013-01-01

    Community and Computing Using Policy Driven Development,” inand Computing Using Policy Driven Development. Proceedings2006). A Framework for Policy Driven Auto- adaptive Systems

  20. Distance Duality Relation from Strong Gravitational Lensing

    E-Print Network [OSTI]

    Liao, Kai; Cao, Shuo; Biesiada, Marek; Zheng, Xiaogang; Zhu, Zong-Hong

    2015-01-01

    Under very general assumptions of metric theory of spacetime, photons traveling along null geodesics and photon number conservation, two observable concepts of cosmic distance, i.e. the angular diameter and the luminosity distances are related to each other by the so called distance duality relation (DDR) $D^L=D^A(1+z)^2$. Observational validation of this relation is quite important because any evidence of its violation could be a signal of new physics. In this letter we introduce a new method to test DDR based on strong gravitational lensing systems and supernovae Ia. Using a new compilation of strong lensing systems and JLA compilation of SNe Ia we found no evidence of DDR violation. However, not so much the final result but the method itself is worth attention, because unlike previously proposed techniques, it does not depend on prior assumptions concerning the details of cosmological model and galaxy cluster modelling.

  1. C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells

    SciTech Connect (OSTI)

    Guo, Pin; Nie, Quanmin; Lan, Jin; Ge, Jianwei [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China)] [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Qiu, Yongming, E-mail: qiuzhoub@hotmail.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China); Mao, Qing, E-mail: maoq@netease.com [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China) [Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 (China); Shanghai Institute of Head Trauma, Shanghai 200127 (China)

    2013-11-08

    Highlights: •The c-Myc oncogene directly upregulates miR-26a expression in GBM cells. •ChIP assays demonstrate that c-Myc interacts with the miR-26a promoter. •Luciferase reporter assays show that PTEN is a specific target of miR-26a. •C-Myc–miR-26a suppression of PTEN may regulate the PTEN/AKT pathway. •Overexpression of c-Myc enhances the proliferative capacity of GBM cells. -- Abstract: The c-Myc oncogene is amplified in many tumor types. It is an important regulator of cell proliferation and has been linked to altered miRNA expression, suggesting that c-Myc-regulated miRNAs might contribute to tumor progression. Although miR-26a has been reported to be upregulated in glioblastoma multiforme (GBM), the mechanism has not been established. We have shown that ectopic expression of miR-26a influenced cell proliferation by targeting PTEN, a tumor suppressor gene that is inactivated in many common malignancies, including GBM. Our findings suggest that c-Myc modulates genes associated with oncogenesis in GBM through deregulation of miRNAs via the c-Myc–miR-26a–PTEN signaling pathway. This may be of clinical relevance.

  2. DemandDriven Pointer Analysis Nevin Heintze

    E-Print Network [OSTI]

    Tardieu, Olivier

    Demand­Driven Pointer Analysis Nevin Heintze Research, Agere Systems (formerly Lucent Technologies analysis of a pro­ gram or program component. In this paper we introduce a demand­driven approach for pointer analysis. Specifically, we describe a demand­driven flow­insensitive, subset­based, context

  3. Cope's Rule & Passive versus Driven Trends

    E-Print Network [OSTI]

    Cope's Rule & Passive versus Driven Trends · Key concepts ­ Traditional explanations of Cope's Rule clade ­ Evolutionary trends can be either passive or driven (or some combination of both). · As a clade diversifies passively the mean increases while the minimum is unchanged. In a driven trend both the mean

  4. The Library for Distance Learners: Engineering

    E-Print Network [OSTI]

    Rzepa, Henry S.

    The Library for Distance Learners: Engineering Joining the Library You need your Library card to enter the Library building; to borrow and renew books; to use the Library's photocopying and printing facilities; and to use the Inter-Library Loans and Bath Copies services. All of the Library's electronic

  5. Structural Alignment Using the Generalized Euclidean Distance

    E-Print Network [OSTI]

    Plotkin, Steven S.

    : 3217­3228, 2009 Key words: protein folding; structural alignment; RMSD; MRSD; generalized distance configurations, and the so-called thermodynamic hypothesis in protein folding was born. This discovery underpinned the formalism that developed decades later to understand protein folding as a configurational

  6. PREPARING THE VIRTUAL CLASSROOM FOR DISTANCE DELIVERY

    E-Print Network [OSTI]

    Dyer, Bill

    of humans and their companion domestic animals and livestock. Students learn that there are certain "at riskPREPARING THE VIRTUAL CLASSROOM FOR DISTANCE DELIVERY: MEDICAL-VETERINARY ENTOMOLOGY CLINICS laboratory," library materials, conventional lectures and the 43 virtual patients in the clinics

  7. miR-196a targets netrin 4 and regulates cell proliferation and migration of cervical cancer cells

    SciTech Connect (OSTI)

    Zhang, Jie; Zheng, Fangxia; Yu, Gang; Yin, Yanhua; Lu, Qingyang

    2013-11-01

    Highlights: •miR-196a was overexpressed in cervical cancer tissue compared to normal tissue. •miR-196a expression elevated proliferation and migration of cervical cancer cells. •miR-196a inhibited NTN4 expression by binding 3?-UTR region of NTN4 mRNA. •NTN4 inversely correlated with miR-196a expression in cervical tissue and cell line. •NTN4 expression was low in cervical cancer tissue compared to normal tissue. -- Abstract: Recent research has uncovered tumor-suppressive and oncogenic potential of miR-196a in various tumors. However, the expression and mechanism of its function in cervical cancer remains unclear. In this study, we assess relative expression of miR-196a in cervical premalignant lesions, cervical cancer tissues, and four cancer cell lines using quantitative real-time PCR. CaSki and HeLa cells were treated with miR-196a inhibitors, mimics, or pCDNA/miR-196a to investigate the role of miR-196a in cancer cell proliferation and migration. We demonstrated that miR-196a was overexpressed in cervical intraepithelial neoplasia 2–3 and cervical cancer tissue. Moreover, its expression contributes to the proliferation and migration of cervical cancer cells, whereas inhibiting its expression led to a reduction in proliferation and migration. Five candidate targets of miR-196a chosen by computational prediction and Cervical Cancer Gene Database search were measured for their mRNA in both miR-196a-overexpressing and -depleted cancer cells. Only netrin 4 (NTN4) expression displayed an inverse association with miR-196a. Fluorescent reporter assays revealed that miR-196a inhibited NTN4 expression by targeting one binding site in the 3?-untranslated region (3?-UTR) of NTN4 mRNA. Furthermore, qPCR and Western blot assays verified NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR-196a expression. In summary, our findings provide new insights about the functional role of miR-196a in cervical carcinogenesis and suggested a potential use of miR-196a for clinical diagnosis and as a therapeutic target.

  8. Electrically-driven optical antennas

    E-Print Network [OSTI]

    Kern, Johannes; Prangsma, Jord C; Emmerling, Monika; Kamp, Martin; Hecht, Bert

    2015-01-01

    Unlike radiowave antennas, optical nanoantennas so far cannot be fed by electrical generators. Instead, they are driven by light or via optically active materials in their proximity. Here, we demonstrate direct electrical driving of an optical nanoantenna featuring an atomic-scale feed gap. Upon applying a voltage, quantum tunneling of electrons across the feed gap creates broadband quantum shot noise. Its optical frequency components are efficiently converted into photons by the antenna. We demonstrate that the properties of the emitted photons are fully controlled by the antenna architecture, and that the antenna improves the quantum efficiency by up to two orders of magnitude with respect to a non-resonant reference system. Our work represents a new paradigm for interfacing electrons and photons at the nanometer scale, e.g. for on-chip wireless data communication, electrically driven single- and multiphoton sources, as well as for background-free linear and nonlinear spectroscopy and sensing with nanometer...

  9. Relevance Weighting Using Distance Between Term Occurrences David Hawking

    E-Print Network [OSTI]

    Hawking, David

    authors. 1 #12;Abstract Recent work has achieved promising retrieval performance using distance between

  10. miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4

    SciTech Connect (OSTI)

    Chen, Liang; Department of Otolaryngology, Guangzhou General Hospital of PLA Guangzhou Command, Guangzhou 510010 ; Tang, Yanping; Wang, Jian; Yan, Zhongjie; Xu, Ruxiang

    2013-06-14

    Highlights: •miR-421 is upregulated in nasopharyngeal carcinoma. •miR-421 induces cell proliferation and apoptosis resistance. •FOXO4 is a direct and functional target of miR-421. -- Abstract: microRNAs have been demonstrated to play important roles in cancer development and progression. Hence, identifying functional microRNAs and better understanding of the underlying molecular mechanisms would provide new clues for the development of targeted cancer therapies. Herein, we reported that a microRNA, miR-421 played an oncogenic role in nasopharyngeal carcinoma. Upregulation of miR-421 induced, whereas inhibition of miR-421 repressed cell proliferation and apoptosis resistance. Furthermore, we found that upregulation of miR-421 inhibited forkhead box protein O4 (FOXO4) signaling pathway following downregulation of p21, p27, Bim and FASL expression by directly targeting FOXO4 3?UTR. Additionally, we demonstrated that FOXO4 expression is critical for miR-421-induced cell growth and apoptosis resistance. Taken together, our findings not only suggest that miR-421 promotes nasopharyngeal carcinoma cell proliferation and anti-apoptosis, but also uncover a novel regulatory mechanism for inactivation of FOXO4 in nasopharyngeal carcinoma.

  11. Single-molecule modeling of mRNA degradation by miRNA: Lessons from data

    E-Print Network [OSTI]

    Celine Sin; Davide Chiarugi; Angelo Valleriani

    2014-10-20

    Recent experimental results on the effect of miRNA on the decay of its target mRNA have been analyzed against a previously hypothesized single molecule degradation pathway. According to that hypothesis, the silencing complex (miRISC) first interacts with its target mRNA and then recruits the protein complexes associated with NOT1 and PAN3 to trigger deadenylation (and subsequent degradation) of the target mRNA. Our analysis of the experimental decay patterns allowed us to refine the structure of the degradation pathways at the single molecule level. Surprisingly, we found that if the previously hypothesized network was correct, only about 7% of the target mRNA would be regulated by the miRNA mechanism, which is inconsistent with the available knowledge. Based on systematic data analysis, we propose the alternative hypothesis that NOT1 interacts with miRISC before binding to the target mRNA. Moreover, we show that when miRISC binds alone to the target mRNA, the mRNA is degraded more slowly, probably through a deadenylation-independent pathway. The new biochemical pathway we propose both fits the data and paves the way for new experimental work to identify new interactions.

  12. Long working distance incoherent interference microscope

    DOE Patents [OSTI]

    Sinclair, Michael B. (Albuquerque, NM); De Boer, Maarten P. (Albuquerque, NM)

    2006-04-25

    A full-field imaging, long working distance, incoherent interference microscope suitable for three-dimensional imaging and metrology of MEMS devices and test structures on a standard microelectronics probe station. A long working distance greater than 10 mm allows standard probes or probe cards to be used. This enables nanometer-scale 3-dimensional height profiles of MEMS test structures to be acquired across an entire wafer while being actively probed, and, optionally, through a transparent window. An optically identical pair of sample and reference arm objectives is not required, which reduces the overall system cost, and also the cost and time required to change sample magnifications. Using a LED source, high magnification (e.g., 50.times.) can be obtained having excellent image quality, straight fringes, and high fringe contrast.

  13. A study of muon neutrino disappearance with the MINOS detectors and the NuMI neutrino beam

    SciTech Connect (OSTI)

    Marshall, John Stuart; /Cambridge U.

    2008-06-01

    This thesis presents the results of an analysis of {nu}{sub {mu}} disappearance with the MINOS experiment, which studies the neutrino beam produced by the NuMI facility at Fermi National Accelerator Laboratory. The rates and energy spectra of charged current {nu}{sub {mu}} interactions are measured in two similar detectors, located at distances of 1 km and 735 km along the NuMI beamline. The Near Detector provides accurate measurements of the initial beam composition and energy, while the Far Detector is sensitive to the effects of neutrino oscillations. The analysis uses data collected between May 2005 and March 2007, corresponding to an exposure of 2.5 x 10{sup 20} protons on target. As part of the analysis, sophisticated software was developed to identify muon tracks in the detectors and to reconstruct muon kinematics. Events with reconstructed tracks were then analyzed using a multivariate technique to efficiently isolate a pure sample of charged current {nu}{sub {mu}} events. An extrapolation method was also developed, which produces accurate predictions of the Far Detector neutrino energy spectrum, based on data collected at the Near Detector. Finally, several techniques to improve the sensitivity of an oscillation measurement were implemented, and a full study of the systematic uncertainties was performed. Extrapolating from observations at the Near Detector, 733 {+-} 29 Far Detector events were expected in the absence of oscillations, but only 563 events were observed. This deficit in event rate corresponds to a significance of 4.3 standard deviations. The deficit is energy dependent and clear distortion of the Far Detector energy spectrum is observed. A maximum likelihood analysis, which fully accounts for systematic uncertainties, is used to determine the allowed regions for the oscillation parameters and identifies the best fit values as {Delta}m{sub 32}{sup 2} = 2.29{sub -0.14}{sup +0.14} x 10{sup -3} eV{sup 2} and sin{sup 2} 2{theta}{sub 23} > 0.953 (68% confidence level). The models of neutrino decoherence and decay are disfavored at the 5.0{sigma} and 3.2{sigma} levels respectively, while the no oscillation model is excluded at the 9.4{sigma} level.

  14. What is the distance to the CMB?

    SciTech Connect (OSTI)

    Clarkson, Chris; Umeh, Obinna; Maartens, Roy; Durrer, Ruth E-mail: umeobinna@gmail.com E-mail: Ruth.Durrer@unige.ch

    2014-11-01

    The success of precision cosmology depends not only on accurate observations, but also on the theoretical model --- which must be understood to at least the same level of precision. Subtle relativistic effects can lead to biased measurements if they are neglected. One such effect gives a systematic shift in the distance-redshift relation away from its background value, due to the non-linear relativistic conservation of total photon flux. We also show directly how this shift follows from a fully relativistic analysis of the geodesic deviation equation. We derive the expectation value of the shift using second-order perturbations about a concordance background, and show that the distance to last scattering is increased by 1%. We argue that neglecting this shift could lead to a significant bias in the background cosmological parameters, because it alters the meaning of the background model. A naive adjustment of CMB parameter estimation if this shift is really a correction to the background would raise the H{sub 0} value inferred from the CMB by 5%, potentially removing the tension with local measurements of H{sub 0}. Other CMB parameters which depend on the distance would also be shifted by ? 1? when combined with local H{sub 0} data. While our estimations rely on a simplistic analysis, they nevertheless illustrate that accurately defining the background model in terms of the expectation values of observables is critical when we aim to determine the model parameters at the sub-percent level.

  15. Flow Distances on Open Flow Networks

    E-Print Network [OSTI]

    Guo, Liangzhu; Shi, Peiteng; Wang, Jun; Huang, Xiaohan; Zhang, Jiang

    2015-01-01

    Open flow network is a weighted directed graph with a source and a sink, depicting flux distributions on networks in the steady state of an open flow system. Energetic food webs, economic input-output networks, and international trade networks, are open flow network models of energy flows between species, money or value flows between industrial sectors, and goods flows between countries, respectively. Flow distances (first-passage or total) between any given two nodes $i$ and $j$ are defined as the average number of transition steps of a random walker along the network from $i$ to $j$ under some conditions. They apparently deviate from the conventional random walk distance on a closed directed graph because they consider the openness of the flow network. Flow distances are explicitly expressed by underlying Markov matrix of a flow system in this paper. With this novel theoretical conception, we can visualize open flow networks, calculating centrality of each node, and clustering nodes into groups. We apply fl...

  16. Actively driven thermal radiation shield

    DOE Patents [OSTI]

    Madden, Norman W. (Livermore, CA); Cork, Christopher P. (Pleasant Hill, CA); Becker, John A. (Alameda, CA); Knapp, David A. (Livermore, CA)

    2002-01-01

    A thermal radiation shield for cooled portable gamma-ray spectrometers. The thermal radiation shield is located intermediate the vacuum enclosure and detector enclosure, is actively driven, and is useful in reducing the heat load to mechanical cooler and additionally extends the lifetime of the mechanical cooler. The thermal shield is electrically-powered and is particularly useful for portable solid-state gamma-ray detectors or spectrometers that dramatically reduces the cooling power requirements. For example, the operating shield at 260K (40K below room temperature) will decrease the thermal radiation load to the detector by 50%, which makes possible portable battery operation for a mechanically cooled Ge spectrometer.

  17. Colliding ionization injection in a beam driven plasma accelerator

    E-Print Network [OSTI]

    Wan, Y; Li, F; Wu, Y P; Hua, J F; Pai, C -H; Lu, W; Joshi, C; Mori, W B; Gu, Y Q

    2015-01-01

    The proposal of generating high quality electron bunches via ionization injection triggered by an counter propagating laser pulse inside a beam driven plasma wake is examined via two-dimensional particle-in-cell simulations. It is shown that electron bunches obtained using this technique can have extremely small slice energy spread, because each slice is mainly composed of electrons ionized at the same time. Another remarkable advantage is that the injection distance is changeable. A bunch with normalized emittance of 3.3 nm, slice energy spread of 15 keV and brightness of 7.2 A m$^{-2}$ rad$^{-2}$ is obtained with an optimal injection length which is achieved by adjusting the launch time of the drive beam or by changing the laser focal position. This makes the scheme a promising approach to generate high quality electron bunches for the fifth generation light source.

  18. Ion-lithium collision dynamics studied with an in-ring MOTReMi

    E-Print Network [OSTI]

    Fischer, D; Goullon, J; Grieser, M; Hubele, R; de Jesus, V L B; Kelkar, A; LaForge, A; Lindenblatt, H; Misra, D; Najjari, B; Schneider, K; Schulz, M; Sell, M; Wang, X

    2012-01-01

    We present a novel experimental tool allowing for kinematically complete studies of break-up processes of laser-cooled atoms. This apparatus, the 'MOTReMi', is a combination of a magneto-optical trap (MOT) and a Reaction Microscope (ReMi). Operated in an ion-storage ring, the new setup enables to study the dynamics in swift ion-atom collisions on an unprecedented level of precision and detail. In first experiments on collisions with 1.5 MeV/amu O$^{8+}$-Li the pure ionization of the valence electron as well as ionization-excitation of the lithium target has been investigated.

  19. Relativistic MHD simulations of poynting flux-driven jets

    SciTech Connect (OSTI)

    Guan, Xiaoyue; Li, Hui; Li, Shengtai

    2014-01-20

    Relativistic, magnetized jets are observed to propagate to very large distances in many active galactic nuclei (AGNs). We use three-dimensional relativistic MHD simulations to study the propagation of Poynting flux-driven jets in AGNs. These jets are already assumed to be being launched from the vicinity (?10{sup 3} gravitational radii) of supermassive black holes. Jet injections are characterized by a model described in Li et al., and we follow the propagation of these jets to ?parsec scales. We find that these current-carrying jets are always collimated and mildly relativistic. When ?, the ratio of toroidal-to-poloidal magnetic flux injection, is large the jet is subject to nonaxisymmetric current-driven instabilities (CDI) which lead to substantial dissipation and reduced jet speed. However, even with the presence of instabilities, the jet is not disrupted and will continue to propagate to large distances. We suggest that the relatively weak impact by the instability is due to the nature of the instability being convective and the fact that the jet magnetic fields are rapidly evolving on Alfvénic time scales. We present the detailed jet properties and show that far from the jet launching region, a substantial amount of magnetic energy has been transformed into kinetic energy and thermal energy, producing a jet magnetization number ? < 1. In addition, we have also studied the effects of a gas pressure supported 'disk' surrounding the injection region, and qualitatively similar global jet behaviors were observed. We stress that jet collimation, CDIs, and the subsequent energy transitions are intrinsic features of current-carrying jets.

  20. Company City State Contact Info 21st Century Plastics Corporation Potterville MI www.21stcpc.com

    E-Print Network [OSTI]

    McGaughey, Alan

    Engineered Plastics, LLC Auburn Hills MI www.deltaengineeredplastics.com Detrex Corporation.dutchlandplastics.com E & O Tool & Plastics, Inc. Elk River MN www.eoplastics.com E & T Plastic Rubber & Plastics Corp. Farmington Hills MI www.exoticautomation.com F & D Plastics, Inc

  1. Data Driven Quality Assurance and Quality Control

    Broader source: Energy.gov [DOE]

    "Data Driven Quality Assurance & Quality Control," Patrick Roche, Conservation Services Group. Provides an overview of data QA/QC system design.

  2. Energy Management for Motor-Driven Systems

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and to design a motor improvement plan. These actions will help you: Reduce energy costs, Improve motor-driven system reliability and efficiency, Increase productivity,...

  3. Distances and absolute magnitudes from trigonometric parallaxes

    E-Print Network [OSTI]

    F. Arenou; X. Luri

    1998-12-04

    We first review the current knowledge of Hipparcos systematic and random errors, in particular small-scale correlations. Then, assuming Gaussian parallax errors and using examples from the recent Hipparcos literature, we show how random errors may be misinterpreted as systematic errors, or transformed into systematic errors. Finally we summarise how to get unbiased estimates of absolute magnitudes and distances, using either Bayesian or non-parametrical methods. These methods may be applied to get either mean quantities or individual estimates. In particular, we underline the notion of astrometry-based luminosity, which avoids the truncation biases and allows a full use of Hipparcos samples.

  4. Roles of the MicroRNA miR-31 in tumor metastasis and an experimental system for the unbiased discovery of genes relevant for breast cancer metastasis

    E-Print Network [OSTI]

    Valastyan, Scott J. (Scott John)

    2010-01-01

    In these studies, the microRNA miR-31 was identified as a potent inhibitor of breast cancer metastasis. miR-31 expression levels were inversely associated with the propensity to develop metastatic disease in human breast ...

  5. Improved Long-Distance Wireless Charging Technology September 26, 2013

    E-Print Network [OSTI]

    Langendoen, Koen

    Improved Long-Distance Wireless Charging Technology September 26, 2013 Project Overview Wireless charging of consumer devices at a long distance with RF technology, would eliminate wires and give freedom

  6. Beyond Kennicott : perceptions of threshold, conceptions of distance

    E-Print Network [OSTI]

    Bull, Steven Keith

    1997-01-01

    Threshold: The thesis explores descriptions of threshold. Threshold is not an ordinary space. It relates to the here and the there and the understanding of distance. It is the phenomena of distance, no matter how close ...

  7. The solar neighborhood. XXXV. Distances to 1404 M dwarf systems...

    Office of Scientific and Technical Information (OSTI)

    solar neighborhood. XXXV. Distances to 1404 M dwarf systems within 25 PC in the southern sky Citation Details In-Document Search Title: The solar neighborhood. XXXV. Distances to...

  8. Perceptions of Distance Education in Newfoundland and Labrador: 1999 2009

    E-Print Network [OSTI]

    Oyet, Alwell

    Perceptions of Distance Education in Newfoundland and Labrador: 1999 ­ 2009 ................................................................................................................. 5 I. Study conducted in 1999 ­ 2000 ........................................................................................................... 80 #12; 5 Perceptions of Distance Education in Newfoundland and Labrador: 1999 2009

  9. Reprinted from the Proceedings of the 1998 ASEE North Central Section Meeting, University of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award )

    E-Print Network [OSTI]

    Bell, John T.

    of Detroit Mercy, Detroit, MI, April 3-4, 1998. ( Best Paper Award ) VIRTUAL REALITY IN CHEMICAL ENGINEERING

  10. BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. Plan for Operational Contingency

    E-Print Network [OSTI]

    Rathbun, Julie A.

    8/29/66 BENDIX SYSTEMS DIVISION ANN AIt 1 o I, MI CH NO. ATM-396 Plan for Operational Contingency of the operational plans and the system design and to study methods of recovery from partial failure through the use. ATM- 396 RIV.MO. A I I f..r I (I IOperational Contingency Study 2 PAGI OP

  11. New Loops! MiTeGen* 50MicroMountsTM consist of a thin microfabricated

    E-Print Network [OSTI]

    Meagher, Mary

    New Loops! MiTeGen* 50µMicroMountsTM consist of a thin microfabricated polyimide film attached to a solid non-magnetic stainless steel pin. The film is polyimide, which is used in Kapton® tape and is employed for X- ray transparent windows on X-ray beam lines. The film is curved by wrapping polyimide film

  12. 2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI

    E-Print Network [OSTI]

    Saitou, Kazuhiro "Kazu"

    2000 JAPAN-USA Symposium on Flexible Automation July 23-26, 2000, Ann Arbor, MI 2000JUSFA-US1 OFF-LINE ERROR RECOVERY LOGIC SYNTHESIS IN AUTOMATED ASSEMBLY LINES BY USING GENETIC PROGRAMMING Cem M. Baydar by the experts or automated error recovery logic controllers embedded in the system. The previous work

  13. An HNF4a-miRNA Inflammatory Feedback Circuit Regulates

    E-Print Network [OSTI]

    An HNF4a-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis Maria, once this circuit is activated, it maintains suppression of HNF4a and sustains oncogenesis. Systemic recapitulate hepatic oncogenesis in various animal models (He et al., 2010). In addition, the inflammatory

  14. AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS

    E-Print Network [OSTI]

    Chen, Ying

    AUSTRALIAN. N~TIONAL UNIVE~SITY DEPARTMENTO:miNUCLEAR PFf-y'SICS 14UD TANK OPENING REPORT/iNo. 51 functions for which it provides power. An order was . immediately placed with N.E.C. for 28 perspex bars microamp hours of b.d.p. generation than its predicted lifetime. In preparation for the next opening

  15. MSU CENTER FOR REGIONAL FOOD SYSTEMS 480 WILSON ROAD, EAST LANSING, MI 48824

    E-Print Network [OSTI]

    AN ANNOTATED BIBLIOGRAPHY ON STRUCTURAL RACISM PRESENT IN THE U.S. FOOD SYSTEM JUNE 2015 #12;Michigan State University Center for Regional Food Systems Structural Racism Present in the U.S. Food System 2 AUTHORS Anel on structural racism present in the U.S. food system. East Lansing, MI: MSU Center for Regional Food Systems

  16. Request for Alternative Activity for PLI Credit Last Name First Name M.I.

    E-Print Network [OSTI]

    Connors, Daniel A.

    Request for Alternative Activity for PLI Credit Full Name: Last Name First Name M.I. Email Address information for Coordinator of Program: Requesting Alternate Activity credit for which PLI Track (Choose one): Verification Information Email Address: College of Engineering Student Information Alternate Activity

  17. MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES

    E-Print Network [OSTI]

    MI FARM TO SCHOOL GRANTEES 2014-2015 PROGRAM YEAR AND PREVIOUS GRANTEES FOODSYSTEMS.MSU.EDU 2014-2015 GRANTEES School/ district/ program County Current Grant Years as a grantee A&W Daycare Wayne Planning 1 TO SCHOOL GRANTEES (2011/12 ­ 2013/14) School/ district/ program County Grant Type(s) Grant Years All Aboard

  18. Compact disposal of high-energy electron beams using passive or laser-driven plasma decelerating stage

    SciTech Connect (OSTI)

    Bonatto, A.; Schroeder, C.B.; Vay, J.-L.; Geddes, C.R.; Benedetti, C.; Esarey and, E.; Leemans, W.P.

    2014-07-13

    A plasma decelerating stage is investigated as a compact alternative for the disposal of high-energy beams (beam dumps). This could benefit the design of laser-driven plasma accelerator (LPA) applications that require transportability and or high-repetition-rate operation regimes. Passive and laser-driven (active) plasma-based beam dumps are studied analytically and with particle-in-cell (PIC) simulations in a 1D geometry. Analytical estimates for the beam energy loss are compared to and extended by the PIC simulations, showing that with the proposed schemes a beam can be efficiently decelerated in a centimeter-scale distance.

  19. OBJECTIVE DISTANCE MEASURES FOR SPECTRAL DISCONTINUITIES IN CONCATENATIVE SPEECH SYNTHESIS

    E-Print Network [OSTI]

    Edinburgh, University of

    - efficientscouldimprovetheprediction. StylianouandSyrdal [4] found that the Kullback-Leibler distance between FFT- based power spectra

  20. Light-driven phase shifter

    DOE Patents [OSTI]

    Early, James W. (Los Alamos, NM)

    1990-01-01

    A light-driven phase shifter is provided for modulating a transmission light beam. A gaseous medium such as argon is provided with electron energy states excited to populate a metastable state. A tunable dye laser is selected with a wavelength effective to deplete the metastable electron state and may be intensity modulated. The dye laser is directed through the gaseous medium to define a first optical path having an index of refraction determined by the gaseous medium having a depleted metastable electron state. A transmission laser beam is also directed through the gaseous medium to define a second optical path at least partially coincident with the first optical path. The intensity of the dye laser beam may then be varied to phase modulate the transmission laser beam.

  1. Preliminaries Conserved Interval Distance between Non-trivial

    E-Print Network [OSTI]

    Blin, Guillaume

    Outline Preliminaries Results Conclusion Conserved Interval Distance between Non-trivial Genomes.Rizzi@unitn.it August the 16th Guillaume Blin, Romeo Rizzi Conserved Interval Distance between Non-trivial Genomes #12 Guillaume Blin, Romeo Rizzi Conserved Interval Distance between Non-trivial Genomes #12;Outline

  2. Problems of Distance-Regular Graphs Hiroshi Suzuki

    E-Print Network [OSTI]

    Xi, Changchang

    ­328. [14] H. Suzuki, The Terwilliger algebra associated with a set of vertices in a distance-regular graph, J. Alg. Combin. 22 (2005), 5-38. [15] P. Terwilliger, Distance-regular graphs and (s, c, a, k)-graphs, J. Combin. Th. (B) 34 (1983), 151­164. [16] P. Terwilliger, A new inequality for distance

  3. Week 4: History / philosophy, distance methods January, 2010

    E-Print Network [OSTI]

    Borenstein, Elhanan

    Week 4: History / philosophy, distance methods Genome 570 January, 2010 Week 4: History Gaylord Simpson (1902-1984) Week 4: History / philosophy, distance methods ­ p.2/73 #12;A horse tree drawn by Simpson Week 4: History / philosophy, distance methods ­ p.3/73 #12;A phylogeny of the living Craniata

  4. Polyphenol-induced Anti-inflammatory and Cytotoxic Activities in Breast and Colon Cancer: Potential Role of miRNA's in Cell Survival and Inflammation 

    E-Print Network [OSTI]

    Banerjee, Nivedita

    2013-12-11

    growth in athymic BALB/c nude mice with BT474 xenografts. Interactions of Pg with miR-27a- ZBTB10-Sp and miR-155-SHIP-1-PI3K axes and mango miR126/PI3K/AKT axis were identified. In addition, pomegranate and plum polyphenols exerted cytotoxic and anti...

  5. SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28-March 4, 1983

    E-Print Network [OSTI]

    Radcliffe, Clark J.

    , Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 #12;SAE 1983 Transactions, Paper No. 830200, pp. 1.810-1.816 International Congress & Exposition, Detroit, Mi., Feb. 28- March 4, 1983 Fig. 2

  6. Adapton: Composable, Demand-Driven Incremental Computation

    E-Print Network [OSTI]

    Hicks, Michael

    Adapton: Composable, Demand-Driven Incremental Computation CS-TR-5027 -- July 12, 2013 Matthew A demands on the program output; that is, if a program input changes, all depen- dencies will be recomputed. To address these problems, we present cdd ic , a core calculus that applies a demand-driven seman- tics

  7. ADAPTON: Composable, Demand-Driven Incremental Computation

    E-Print Network [OSTI]

    Hicks, Michael

    ADAPTON: Composable, Demand- Driven Incremental Computation Abstract Many researchers have proposed important drawbacks. First, recomputation is oblivious to specific demands on the program output; that is ic , a core calculus that applies a demand-driven semantics to incremental computa- tion, tracking

  8. SUPERNOVAE AND AGN DRIVEN GALACTIC OUTFLOWS

    SciTech Connect (OSTI)

    Sharma, Mahavir; Nath, Biman B. E-mail: biman@rri.res.in

    2013-01-20

    We present analytical solutions for winds from galaxies with a Navarro-Frank-White (NFW) dark matter halo. We consider winds driven by energy and mass injection from multiple supernovae (SNe), as well as momentum injection due to radiation from a central black hole. We find that the wind dynamics depends on three velocity scales: (1) v{sub *}{approx}( E-dot / 2 M-dot ){sup 1/2} describes the effect of starburst activity, with E-dot and M-dot as energy and mass injection rate in a central region of radius R; (2) v {sub .} {approx} (GM {sub .}/2R){sup 1/2} for the effect of a central black hole of mass M {sub .} on gas at distance R; and (3) v{sub s}=(GM{sub h} / 2Cr{sub s}){sup 1/2}, which is closely related to the circular speed (v{sub c} ) for an NFW halo, where r{sub s} is the halo scale radius and C is a function of the halo concentration parameter. Our generalized formalism, in which we treat both energy and momentum injection from starbursts and radiation from the central active galactic nucleus (AGN), allows us to estimate the wind terminal speed to be (4v {sup 2} {sub *} + 6({Gamma} - 1)v {sub .} {sup 2} - 4v {sup 2} {sub s}){sup 1/2}, where {Gamma} is the ratio of force due to radiation pressure to gravity of the central black hole. Our dynamical model also predicts the following: (1) winds from quiescent star-forming galaxies cannot escape from 10{sup 11.5} M {sub Sun} {<=} M{sub h} {<=} 10{sup 12.5} M {sub Sun} galaxies; (2) circumgalactic gas at large distances from galaxies should be present for galaxies in this mass range; (3) for an escaping wind, the wind speed in low- to intermediate-mass galaxies is {approx}400-1000 km s{sup -1}, consistent with observed X-ray temperatures; and (4) winds from massive galaxies with AGNs at Eddington limit have speeds {approx}> 1000 km s{sup -1}. We also find that the ratio [2v {sup 2} {sub *} - (1 - {Gamma})v {sub .} {sup 2}]/v {sup 2} {sub c} dictates the amount of gas lost through winds. Used in conjunction with an appropriate relation between M {sub .} and M{sub h} and an appropriate opacity of dust grains in infrared (K band), this ratio has the attractive property of being minimum at a certain halo mass scale (M{sub h} {approx} 10{sup 12}-10{sup 12.5} M {sub Sun }) that signifies the crossover of AGN domination in outflow properties from starburst activity at lower masses. We find that stellar mass for massive galaxies scales as M {sub *}{proportional_to}M {sup 0.26} {sub h}, and for low-mass galaxies, M {sub *}{proportional_to}M {sup 5/3} {sub h}.

  9. MiR-18a regulates the proliferation, migration and invasion of human glioblastoma cell by targeting neogenin

    SciTech Connect (OSTI)

    Song, Yichen; Wang, Ping; Zhao, Wei; Yao, Yilong; Liu, Xiaobai; Ma, Jun; Xue, Yixue; Liu, Yunhui

    2014-05-15

    MiR-17-92 cluster has recently been reported as an oncogene in some tumors. However, the association of miR-18a, an important member of this cluster, with glioblastoma remains unknown. Therefore, this study aims to investigate the expression of miR-18a in glioblastoma and its role in biological behavior of U87 and U251 human glioblastoma cell lines. Quantitative RT-PCR results showed that miR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines compared with that in human brain tissues and primary normal human astrocytes, and the expression levels were increased along with the rising pathological grades of glioblastoma. Neogenin was identified as the target gene of miR-18a by dual-luciferase reporter assays. RT-PCR and western blot results showed that its expression levels were decreased along with the rising pathological grades of glioblastoma. Inhibition of miR-18a expression was established by transfecting exogenous miR-18a inhibitor into U87 and U251 cells, and its effects on the biological behavior of glioblastoma cells were studied using CCK-8 assay, transwell assay and flow cytometry. Inhibition of miR-18a expression in U87 and U251 cells significantly up-regulated neogenin, and dramatically suppressed the abilities of cell proliferation, migration and invasion, induced cell cycle arrest and promoted cellular apoptosis. Collectively, these results suggest that miR-18a may regulate biological behavior of human glioblastoma cells by targeting neogenin, and miR-18a can serve as a potential target in the treatment of glioblastoma. - Highlights: • MiR-18a was highly expressed in glioblastoma tissues and U87 and U251 cell lines. • Neogenin was identified as the target gene of miR-18a. • Neogenin expressions were decreased along with the rising pathological grades of glioblastoma. • Inhibition of miR-18a suppressed biological behavior of glioma cells by up-regulating neogenin.

  10. A Market-Driven Approach to Product Family Design A Market-Driven Approach to Product Family Design

    E-Print Network [OSTI]

    Chen, Wei

    A Market-Driven Approach to Product Family Design 1 A Market-Driven Approach to Product Family@psu.edu. #12;A Market-Driven Approach to Product Family Design 2 A Market-Driven Approach to Product Family research interests are in demand modeling, decision-based design, and market-driven product family design

  11. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

    SciTech Connect (OSTI)

    Li, Qiaoyan; Zhu, Fufan; Chen, Puxiang

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Both miR-7 and miR-218 down-regulates HoxB3 expression by targeting the 3 Prime -UTR of HoxB3 mRNA. Black-Right-Pointing-Pointer A reverse correlation between the levels of endogenous miR-7, miR218 and HoxB3 expression. Black-Right-Pointing-Pointer Epigenetic changes involve in the reactivation of HoxB3. Black-Right-Pointing-Pointer Both miRNAs inhibits the cell cycle and clone formation of breast cancer cells. -- Abstract: Many microRNAs have been implicated as key regulators of cellular growth and differentiation and have been found to dysregulate proliferation in human tumors, including breast cancer. Cancer-linked microRNAs also alter the epigenetic landscape by way of DNA methylation and post-translational modifications of histones. Aberrations in Hox gene expression are important for oncogene or tumor suppressor during abnormal development and malignancy. Although recent studies suggest that HoxB3 is critical in breast cancer, the putative role(s) of microRNAs impinging on HoxB3 is not yet fully understood. In this study, we found that the expression levels of miR-7 and miR-218 were strongly and reversely associated with HoxB3 expression. Stable overexpression of miR-7 and miR-218 was accompanied by reactivation of tumor suppressor genes including RASSF1A and Claudin-6 by means of epigenetic switches in DNA methylation and histone modification, giving rise to inhibition of the cell cycle and clone formation of breast cancer cells. The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.

  12. Long Range Force Transmission in Fibrous Matrices Enabled by Tension-Driven Alignment of Fibers

    E-Print Network [OSTI]

    Hailong Wang; Abhilash Nair; Christopher S. Chen; Rebecca G. Wells; Vivek B. Shenoy

    2014-09-23

    Cells can sense and respond to mechanical signals over relatively long distances across fibrous extracellular matrices. Here, we explore all of the key factors that influence long range force transmission in cell-populated collagen matrices: alignment of collagen fibers, responses to applied force, strain stiffening properties of the aligned fibers, aspect ratios of the cells, and the polarization of cellular contraction. A constitutive law accounting for mechanically-driven collagen fiber reorientation is proposed. We systematically investigate the range of collagen fiber alignment using both finite element simulations and analytical calculations. Our results show that tension-driven collagen fiber alignment plays a crucial role in force transmission. Small critical stretch for fiber alignment, large fiber stiffness and fiber strain hardening behavior enable long-range interaction. Furthermore, the range of collagen fiber alignment for elliptical cells with polarized contraction is much larger than that for spherical cells with diagonal contraction. A phase diagram showing the range of force transmission as a function of cell shape and polarization and matrix properties is presented. Our results are in good agreement with recent experiments, and highlight the factors that influence long-range force transmission, in particular tension-driven alignment of fibers. Our work has important relevance to biological processes including development, cancer metastasis and wound healing, suggesting conditions whereby cells communicate over long distances.

  13. Continuous Energy Improvement in Motor Driven Systems - A Guidebook...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Improvement in Motor Driven Systems - A Guidebook for Industry Continuous Energy Improvement in Motor Driven Systems - A Guidebook for Industry This guidebook provides a...

  14. Solving Customer-Driven Microgrid Optimization Problems as DCOPs

    E-Print Network [OSTI]

    Yeoh, William

    Solving Customer-Driven Microgrid Optimization Problems as DCOPs Saurabh Gupta , Palak Jain common customer-driven microgrid (CDMG) optimization problems ­ a comprehensive CDMG optimization problem

  15. Engine Driven Combined Heat and Power: Arrow Linen Supply, December...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Engine Driven Combined Heat and Power: Arrow Linen Supply, December 2008 Engine Driven Combined Heat and Power: Arrow Linen Supply, December 2008 This paper describes the Arrow...

  16. United States Industrial Motor-Driven Systems Market Assessment...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    United States Industrial Motor-Driven Systems Market Assessment: Charting a Roadmap to Energy Savings for Industry United States Industrial Motor-Driven Systems Market Assessment:...

  17. DEVELOPMENT OF SOLAR DRIVEN ABSORPTION AIR CONDITIONERS AND HEAT PUMPS

    E-Print Network [OSTI]

    Dao, K.

    2013-01-01

    driver, driven by high pressure vapor. DW: main circulationpump driven by high pressure vapor. ~ restrictors ~ checkof the amount of high pressure vapor used to run the pump

  18. Energy Department Launches New Data-Driven Initiative to Help...

    Energy Savers [EERE]

    Launches New Data-Driven Initiative to Help Cities, States Advance Building Efficiency Energy Department Launches New Data-Driven Initiative to Help Cities, States Advance Building...

  19. Separated response functions in exclusive, forward <mi>?>± electroproduction on deuterium

    SciTech Connect (OSTI)

    Huber, G. M.; Blok, H. P.; Butuceanu, C.; Gaskell, D.; Horn, T.; Mack, D. J.; Abbott, D.; Aniol, K.; Anklin, H.; Armstrong, C.; Arrington, J.; Assamagan, K.; Avery, S.; Baker, O. K.; Barrett, B.; Beise, E. J.; Bochna, C.; Boeglin, W.; Brash, E. J.; Breuer, H.; Chang, C. C.; Chant, N.; Christy, M. E.; Dunne, J.; Eden, T.; Ent, R.; Fenker, H.; Gibson, E. F.; Gilman, R.; Gustafsson, K.; Hinton, W.; Holt, R. J.; Jackson, H.; Jin, S.; Jones, M. K.; Keppel, C. E.; Kim, P. H.; Kim, W.; King, P. M.; Klein, A.; Koltenuk, D.; Kovaltchouk, V.; Liang, M.; Liu, J.; Lolos, G. J.; Lung, A.; Margaziotis, D. J.; Markowitz, P.; Matsumura, A.; McKee, D.; Meekins, D.; Mitchell, J.; Miyoshi, T.; Mkrtchyan, H.; Mueller, B.; Niculescu, G.; Niculescu, I.; Okayasu, Y.; Pentchev, L.; Perdrisat, C.; Pitz, D.; Potterveld, D.; Punjabi, V.; Qin, L. M.; Reimer, P. E.; Reinhold, J.; Roche, J.; Roos, P. G.; Sarty, A.; Shin, I. K.; Smith, G. R.; Stepanyan, S.; Tang, L. G.; Tadevosyan, V.; Tvaskis, V.; van der Meer, R. L.J.; Vansyoc, K.; Van Westrum, D.; Vidakovic, S.; Volmer, J.; Vulcan, W.; Warren, G.; Wood, S. A.; Xu, C.; Yan, C.; Zhao, W. X.; Zheng, X.; Zihlmann, B.

    2015-01-01

    Background: Measurements of forward exclusive meson production at different squared four-momenta of the exchanged virtual photon, Q2, and at different four-momentum transfer, t, can be used to probe QCD's transition from meson-nucleon degrees of freedom at long distances to quark-gluon degrees of freedom at short scales. Ratios of separated response functions in ?? and ?? electroproduction are particularly informative. The ratio for transverse photons may allow this transition to be more easily observed, while the ratio for longitudinal photons provides a crucial verification of the assumed pole dominance, needed for reliable extraction of the pion form factor from electroproduction data. Method: Data were acquired with 2.6-5.2 GeV electron beams and the HMS+SOS spectrometers in Jefferson Lab Hall C, at central Q2 values of 0.6, 1.0, 1.6 GeV2 at W=1.95 GeV, and Q2=2.45 GeV2 at W=2.22 GeV. There was significant coverage in ? And ?, which allowed separation of ?L,T,LT,TT. Results: ?L shows a clear signature of the pion pole, with a sharp rise at small -t. In contrast, ?T is much flatter versus t. The longitudinal/transverse ratios evolve with Q2 and t, and at the highest Q2=2.45 GeV2 show a slight enhancement for ?? Production compared to ??. The ??/??+ ratio for transverse photons exhibits only a small Q2-dependence, following a nearly universal curve with t, with a steep transition to a value of about 0.25, consistent with s-channel quark knockout. The ?TT/?T ratio also drops rapidly with Q2, qualitatively consistent with s-channel helicity conservation. The ??/?? ratio for longitudinal photons indicates a small isoscalar contamination at W=1.95 GeV, consistent with what was observed in our earlier determination of the pion form factor at these kinematics.

  20. Space efficient streaming algorithms for the distance to monotonicity and asymmetric edit distance

    E-Print Network [OSTI]

    Saks, Michael

    2012-01-01

    Approximating the length of the longest increasing sequence (LIS) of a data stream is a well-studied problem. There are many algorithms that estimate the size of the complement of the LIS, referred to as the \\emph{distance to monotonicity}, both in the streaming and property testing setting. Let $n$ denote the size of an input array. Our aim is to develop a one-pass streaming algorithm that accurately approximates the distance to monotonicity, and only uses polylogarithmic storage. For any $\\delta > 0$, our algorithm provides a $(1+\\delta)$-multiplicative approximation for the distance, and uses only $O((\\log^2 n)/\\delta)$ space. The previous best known approximation using poly-logarithmic space was a multiplicative 2-factor. Our algorithm is simple and natural, being just 3 lines of pseudocode. It is essentially a polylogarithmic space implementation of a classic dynamic program that computes the LIS. Our technique is more general and is applicable to other problems that are exactly solvable by dynamic progr...

  1. Novel applications of diffusion-driven flow

    E-Print Network [OSTI]

    Allshouse, Michael R

    2010-01-01

    Diffusion-driven flow is the result of a conflict between hydrostatic equilibrium in a density stratified fluid and the no-flux boundary condition that must be obeyed on impermeable boundaries that are sloping with respect ...

  2. Gravity-Driven Intrusions in Stratified Fluids

    E-Print Network [OSTI]

    Maurer, Benjamin D.

    2011-01-01

    5.5.1 Five interleaving interfacial gravity currents 5.5.2Ten interleaving interfacial gravity currents . 5.6in Iceland showing multiple gravity-driven intrusions c ´

  3. Buffer assignment algorithms for data driven architectures 

    E-Print Network [OSTI]

    Chatterjee, Mitrajit

    1994-01-01

    Data driven architectures designed to achieve high performance and throughput require the corresponding data flow graph to have no accumulation of data at its nodes and simultaneous arrival of all input data to a multi-input node. Buffers...

  4. Life Science & Technology Delft: Driven by curiosity,

    E-Print Network [OSTI]

    Langendoen, Koen

    Life Science & Technology Delft: Driven by curiosity, inspired by application. Diploma Master & Technology addresses the understanding of enzymes, living cells and biotechnological processes. Based' airplane fuels. The MSc programme in Life Science & Technology seeks to train the scientists and engineers

  5. Electric Driven Heat Pumps in Distillation Processes 

    E-Print Network [OSTI]

    Harris, G. E.

    1983-01-01

    Radian Corporation, under contract to the Electric Power Research Institute, has recently completed a study of the potential range of application for retrofitting electric driven heat pumps to existing distillation columns. ...

  6. PIANO DI RIQUALIFICAZIONE AMBIENTALE E PAESAGGISTICA DEL TERMOVALORIZZATORE DI DESIO TERMOVALORIZZATORE DI DESIO (MI) BRIANZA ENERGIA E AMBIENTE SPA

    E-Print Network [OSTI]

    Columbia University

    TERMOVALORIZZATORE DI DESIO (MI) ­ BRIANZA ENERGIA E AMBIENTE SPA Impianto di costruito negli anni '70 per lo. · Energia elettrica prodotta: 13.000.000 KWh/anno. LAND S.r.l. Landscape Architecture Nature Development

  7. The Effect of Metallicity on Cepheid-Based Distances

    E-Print Network [OSTI]

    Shoko Sakai; Laura Ferrarese; Rob Kennicutt; Abi Saha

    2004-02-20

    We have used the Wide Field and Planetary Camera 2 on board the Hubble Space Telescope to obtain V and I images of seven nearby galaxies. For each, we have measured a distance using the tip of the red giant branch (TRGB) method. By comparing the TRGB distances to published Cepheid distances, we investigate the metallicity dependence of the Cepheid period-luminosity relation. Our sample is supplemented by 10 additional galaxies for which both TRGB and Cepheid distances are available in the literature, thus providing a uniform coverage in Cepheid abundances between 1/20 and 2 (O/H)solar. We find that the difference between Cepheid and TRGB distances decreases monotonically with increasing Cepheid abundance, consistent with a mean metallicity dependence of the Cepheid distance moduli of (delta(m-M))/(delta[O/H]) = -0.24 +- 0.05 mag/dex.

  8. A thin film transistor driven microchannel device 

    E-Print Network [OSTI]

    Lee, Hyun Ho

    2005-02-17

    THIN FILM TRANSISTOR DRIVEN MICROCHANNEL DEVICE FOR PROTEIN AND DNA ELECTROPHORESIS A Dissertation by HYUN HO LEE Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements... for the degree of DOCTOR OF PHILOSOPHY December 2004 Major Subject: Chemical Engineering A THIN FILM TRANSISTOR DRIVEN MICROCHANNEL DEVICE FOR PROTEIN AND DNA ELECTROPHORESIS A Dissertation by HYUN HO LEE Submitted to Texas A...

  9. Cepheid Variables and their Application to the Cosmological Distance Scale 

    E-Print Network [OSTI]

    Hoffmann, Samantha L

    2013-05-02

    . . . . . . . . . . . . . . . . . . . . . . . . . . 55 3. DIFFERENCE IMAGING ANALYSIS OF TYPE IA SUPERNOVA HOST NGC 5584 FOR CEPHEID VARIABLES . . . . . . . . . . . . . . . . . . 63 3.1 Motivation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 3.2 Observations and Data Reduction... and type Ia supernovae (SNe Ia). This cosmological distance scale started with a geometric distance measurement of Cepheids, such as parallaxes by [5]. The Cepheid Period-Luminosity relation was characterized by [79] for use as a primary distance...

  10. Measurement of Pi-K Ratios from the NuMI Target

    SciTech Connect (OSTI)

    Seun, Sin Man; /Harvard U.

    2007-07-01

    Interactions of protons (p) with the NuMI (Neutrinos at the Main Injector) target are used to create the neutrino beam for the MINOS (Main Injector Neutrino Oscillation Search) Experiment. Using the MIPP (Main Injector Particle Production) experimental apparatus, the production of charged pions and kaons in p+NuMI interactions is studied. The data come from a sample of 2 x 10{sup 6} events obtained by MIPP using the 120 GeV/c proton beam from the Main Injector at Fermi National Accelerator Laboratory in Illinois, USA. Pions and kaons are identified by measurement in a Ring Imaging Cherenkov detector. Presented are measurements of {pi}{sup -}/{pi}{sup +}, K{sup -}/K{sup +}, {pi}{sup +}/K{sup +} and {pi}{sup -}/K{sup -} production ratios in the momentum range p{sub T} < 2 GeV/c transversely and 20 GeV/c < p{sub z} < 90 GeV/c longitudinally. Also provided are detailed comparisons of the MIPP NuMI data with the MIPP Thin Carbon data, the MIPP Monte Carlo simulation and the current MINOS models in the relevant momentum ranges.

  11. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

    SciTech Connect (OSTI)

    Deng, Jun; Lei, Wan; Fu, Jian-Chun; Zhang, Ling; Li, Jun-He; Xiong, Jian-Ping

    2014-01-17

    Highlight: •MiR-21 plays a significant role in 5-FU resistance. •This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. •Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. -- Abstract: 5-Fluorouracil (5-FU) is a classic chemotherapeutic drug that has been widely used for colorectal cancer treatment, but colorectal cancer cells are often resistant to primary or acquired 5-FU therapy. Several studies have shown that miR-21 is significantly elevated in colorectal cancer. This suggests that this miRNA might play a role in this resistance. In this study, we investigated this possibility and the possible mechanism underlying this role. We showed that forced expression of miR-21 significantly inhibited apoptosis, enhanced cell proliferation, invasion, and colony formation ability, promoted G1/S cell cycle transition and increased the resistance of tumor cells to 5-FU and X radiation in HT-29 colon cancer cells. Furthermore, knockdown of miR-21 reversed these effects on HT-29 cells and increased the sensitivity of HT-29/5-FU to 5-FU chemotherapy. Finally, we showed that miR-21 targeted the human mutS homolog2 (hMSH2), and indirectly regulated the expression of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). These results demonstrate that miR-21 may play an important role in the 5-FU resistance of colon cancer cells.

  12. Discovering the Nature of Dark Energy: Towards Better Distances...

    Office of Scientific and Technical Information (OSTI)

    Discovering the Nature of Dark Energy: Towards Better Distances from Type Ia Supernovae -- Final Technical Report Filippenko, Alexei Vladimir Univ. California, Berkeley 79...

  13. The Design, Construction, and Operation of Long-Distance High...

    Open Energy Info (EERE)

    The Design, Construction, and Operation of Long-Distance High-Voltage Electricity Transmission Technologies Jump to: navigation, search OpenEI Reference LibraryAdd to library...

  14. Risk Distance: The Loss of Strength Gradient and Colombia's Geography of Impunity

    E-Print Network [OSTI]

    Demarest, Geoffrey

    2013-12-31

    The dissertation proposes a theoretical category of distance, risk distance, as a prompt for understanding outcomes in internal armed struggles. Geographers are familiar with cost distance -- conceiving distance according ...

  15. Ris-R-1518(EN) The necessary distance between large

    E-Print Network [OSTI]

    Risø-R-1518(EN) The necessary distance between large wind farms offshore - study Sten Frandsen. As it is often the need for offshore wind farms, the model handles a regular array-geometry with straight rows distance between large wind farms in the offshore environment. The main results are given in Section 1

  16. A novel molecular index for secondary oil migration distance

    E-Print Network [OSTI]

    alteration of buried organic matter in source rocks, followed by oil expulsion (primary migration) outA novel molecular index for secondary oil migration distance Liuping Zhang1 , Maowen Li2 , Yang migration distances from source rocks to reservoirs can greatly help in the search for new petroleum

  17. On maximal instances for the original syntenic distance Cedric Chauve

    E-Print Network [OSTI]

    Chauve, Cedric

    genomes has been introduced by Ferretti, Nadeau and Sanko#11; as an approximation of the evolutionary distance between genomes for which the gene order is not known. This distance is the minimum number of fusions, #12;ssions and translocations required to transform a genome into an other. Kleinberg and Liben

  18. CHAOTIC DATA ENCRYPTION FOR LONG-DISTANCE MONITORING OF NUCLEAR

    E-Print Network [OSTI]

    Koksal, Can Emre

    matrix = Lorenz system parameter = Lorenz system parameter = excess delayed neutron precursorsCHAOTIC DATA ENCRYPTION FOR LONG-DISTANCE MONITORING OF NUCLEAR REACTORS Günyaz Ablay The Ohio DATA ENCRYPTION FOR LONG-DISTANCE MONITORING OF NUCLEAR REACTORS Günyaz Ablay1 , C. Emre Koksal2

  19. Patterns in Offender Distance Decay and the Geographic Profiling Problem.

    E-Print Network [OSTI]

    O'Leary, Michael

    Patterns in Offender Distance Decay and the Geographic Profiling Problem. Mike O'Leary Towson University 2010 Fall Western Section Meeting Los Angeles, CA October 9-10, 2010 Mike O'Leary (Towson Department for his assistance. Mike O'Leary (Towson University) Offender Distance Decay October 9, 2010 2

  20. Patterns in Offender Distance Decay and the Geographic Profiling Problem.

    E-Print Network [OSTI]

    O'Leary, Michael

    Patterns in Offender Distance Decay and the Geographic Profiling Problem. Mike O'Leary Towson University 2011 Crime Mapping Conference Miami, FL October 19-21, 2011 Mike O'Leary (Towson University Department for his assistance. Mike O'Leary (Towson University) Offender Distance Decay October 21, 2011 2

  1. Risk-driven Security Testing versus Test-driven Security Risk Analysis

    E-Print Network [OSTI]

    Stølen, Ketil

    Risk-driven Security Testing versus Test-driven Security Risk Analysis Gencer Erdogan1 the combinations of se- curity testing and security risk analysis depending on whether it is viewed from a security testing perspective or a security risk analysis perspective. The main focus in the former view is security

  2. MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway

    SciTech Connect (OSTI)

    Ma, Yanfei; Qin, Huadong [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of Fourth Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China); Cui, Yunfu, E-mail: yfma77@126.com [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)] [Department of First Surgery, the Second Affiliated Hospital of Harbin Medical University, 148 Xuefu Road, Nangang District, Harbin 150086 (China)

    2013-11-29

    Highlights: •MiR-34a is up- and GAS1 is down-regulated in papillary thyroid carcinoma. •GAS1 is a direct target for miR-34a. •MiR-34a promotes PTC cells proliferation and inhibits apoptosis through PI3K/Akt/Bad pathway. -- Abstract: MicroRNAs (miRNAs) are fundamental regulators of cell proliferation, differentiation, and apoptosis, and are implicated in tumorigenesis of many cancers. MiR-34a is best known as a tumor suppressor through repression of growth factors and oncogenes. Growth arrest specific1 (GAS1) protein is a tumor suppressor that inhibits cancer cell proliferation and induces apoptosis through inhibition of RET receptor tyrosine kinase. Both miR-34a and GAS1 are frequently down-regulated in various tumors. However, it has been reported that while GAS1 is down-regulated in papillary thyroid carcinoma (PTC), miR-34a is up-regulated in this specific type of cancer, although their potential roles in PTC tumorigenesis have not been examined to date. A computational search revealed that miR-34a putatively binds to the 3?-UTR of GAS1 gene. In the present study, we confirmed previous findings that miR-34a is up-regulated and GAS1 down-regulated in PTC tissues. Further studies indicated that GAS1 is directly targeted by miR-34a. Overexpression of miR-34a promoted PTC cell proliferation and colony formation and inhibited apoptosis, whereas knockdown of miR-34a showed the opposite effects. Silencing of GAS1 had similar growth-promoting effects as overexpression of miR-34a. Furthermore, miR-34a overexpression led to activation of PI3K/Akt/Bad signaling pathway in PTC cells, and depletion of Akt reversed the pro-growth, anti-apoptotic effects of miR-34a. Taken together, our results demonstrate that miR-34a regulates GAS1 expression to promote proliferation and suppress apoptosis in PTC cells via PI3K/Akt/Bad pathway. MiR-34a functions as an oncogene in PTC.

  3. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: •MiR-145 is downregulated in human ovarian cancer. •MiR-145 targets p70S6K1 and MUC1. •p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  4. Kinetic distance and kinetic maps from molecular dynamics simulation

    E-Print Network [OSTI]

    Noe, Frank

    2015-01-01

    Characterizing macromolecular kinetics from molecular dynamics (MD) simulations requires a distance metric that can distinguish slowly-interconverting states. Here we build upon diffusion map theory and define a kinetic distance for irreducible Markov processes that quantifies how slowly molecular conformations interconvert. The kinetic distance can be computed given a model that approximates the eigenvalues and eigenvectors (reaction coordinates) of the MD Markov operator. Here we employ the time-lagged independent component analysis (TICA). The TICA components can be scaled to provide a kinetic map in which the Euclidean distance corresponds to the kinetic distance. As a result, the question of how many TICA dimensions should be kept in a dimensionality reduction approach becomes obsolete, and one parameter less needs to be specified in the kinetic model construction. We demonstrate the approach using TICA and Markov state model (MSM) analyses for illustrative models, protein conformation dynamics in bovine...

  5. Terahertz-driven linear electron acceleration

    E-Print Network [OSTI]

    Nanni, Emilio Alessandro; Ravi, Koustuban; Fallahi, Arya; Moriena, Gustavo; Miller, R J Dwayne; Kärtner, Franz X

    2014-01-01

    The cost, size and availability of electron accelerators is dominated by the achievable accelerating gradient. Conventional high-brightness radio-frequency (RF) accelerating structures operate with 30-50 MeV/m gradients. Electron accelerators driven with optical or infrared sources have demonstrated accelerating gradients orders of magnitude above that achievable with conventional RF structures. However, laser-driven electron accelerators require intense sources and suffer from low bunch charge, sub-micron tolerances and sub-femtosecond timing requirements due to the short wavelength of operation. Here, we demonstrate the first linear acceleration of electrons with keV energy gain using optically-generated terahertz (THz) pulses. THz-driven accelerating structures enable high-gradient electron accelerators with simple accelerating structures, high repetition rates and significant charge per bunch. Increasing the operational frequency of accelerators into the THz band allows for greatly increased accelerating ...

  6. Driven cavity flow: from molecular dynamics to continuum hydrodynamics

    E-Print Network [OSTI]

    Tiezheng Qian; Xiao-Ping Wang

    2004-03-06

    Molecular dynamics (MD) simulations have been carried out to investigate the slip of fluid in the lid driven cavity flow where the no-slip boundary condition causes unphysical stress divergence. The MD results not only show the existence of fluid slip but also verify the validity of the Navier slip boundary condition. To better understand the fluid slip in this problem, a continuum hydrodynamic model has been formulated based upon the MD verification of the Navier boundary condition and the Newtonian stress. Our model has no adjustable parameter because all the material parameters (density, viscosity, and slip length) are directly determined from MD simulations. Steady-state velocity fields from continuum calculations are in quantitative agreement with those from MD simulations, from the molecular-scale structure to the global flow. The main discovery is as follows. In the immediate vicinity of the corners where moving and fixed solid surfaces intersect, there is a core partial-slip region where the slippage is large at the moving solid surface and decays away from the intersection quickly. In particular, the structure of this core region is nearly independent of the system size. On the other hand, for sufficiently large system, an additional partial-slip region appears where the slippage varies as $1/r$ with $r$ denoting the distance from the corner along the moving solid surface. The existence of this wide power-law region is in accordance with the asymptotic $1/r$ variation of stress and the Navier boundary condition.

  7. Motor driven microtubule shape fluctuations - force from within the lattice

    E-Print Network [OSTI]

    Herve Mohrbach; Igor M. Kulic

    2007-04-15

    We develop a general theory of microtubule (MT) deformations by molecular motors generating internal force doublets within the MT lattice. We describe two basic internal excitations, the S and V shape, and compare them with experimental observations from literature. We explain the special role of tubulin vacancies and the dramatic deformation amplifying effect observed for katanin acting at positions of defects. Experimentally observed shapes are used to determine the ratio of MT shear and stretch moduli ($\\approx 6\\times10^{-5}$) and to estimate the forces induced in the MT lattice by katanin (10's of pN). For many motors acting on a single MT we derive expressions for the end-to-end distance reduction and provide criteria for dominance of this new effect over thermal fluctuations. We conclude that molecular motors if acting cooperatively can ''animate'' MTs from within the lattice and induce slack even without cross-bridging to other structures, a scenario very much reminiscent of the motor driven axoneme.

  8. Testing CPT conservation using the NuMI neutrino beam with the MINOS experiment

    SciTech Connect (OSTI)

    Auty, David John; /Sussex U.

    2010-05-01

    The MINOS experiment was designed to measure neutrino oscillation parameters with muon neutrinos. It achieves this by measuring the neutrino energy spectrum and flavor composition of the man-made NuMI neutrino beam 1km after the beam is formed and again after 735 km. By comparing the two spectra it is possible to measure the oscillation parameters. The NuMI beam is made up of 7.0% {bar {nu}}{sub {mu}}, which can be separated from the {nu}{sub {mu}} because the MINOS detectors are magnetized. This makes it possible to study {bar {nu}}{sub {mu}} oscillations separately from those of muon neutrinos, and thereby test CPT invariance in the neutrino sector by determining the {bar {nu}}{sub {mu}} oscillation parameters and comparing them with those for {nu}{sub {mu}}, although any unknown physics of the antineutrino would appear as a difference in oscillation parameters. Such a test has not been performed with beam {bar {nu}}{sub {mu}} before. It is also possible to produce an almost pure {bar {nu}}{sub {mu}} beam by reversing the current through the magnetic focusing horns of the NuMI beamline, thereby focusing negatively, instead of positively charged particles. This thesis describes the analysis of the 7% {bar {nu}}{sub {mu}} component of the forward horn current NuMI beam. The {bar {nu}}{sub {mu}} of a data sample of 3.2 x 10{sup 20} protons on target analysis found 42 events, compared to a CPT conserving prediction of 58.3{sub -7.6}{sup +7.6}(stat.){sub -3.6}{sup +3.6}(syst.) events. This corresponds to a 1.9 {sigma} deficit, and a best fit value of {Delta}{bar m}{sub 32}{sup 2} = 18 x 10{sup -3} eV{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23} = 0.55. This thesis focuses particularly on the selection of {bar {nu}}{sub {mu}} events, and investigates possible improvements of the selection algorithm. From this a different selector was chosen, which corroborated the findings of the original selector. The thesis also investigates how the systematic errors affect the precision of {Delta}{bar m}{sub 32}{sup 2} and sin{sup 2} 2{bar {theta}}{sub 23}. Furthermore, it describes a study to determine the gains of the PMTs via the single-photoelectron spectrum. The results were used as a crosscheck of the gains determined at higher intensities by an LED-based light-injection system.

  9. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See Block 16C I

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal GasAdministration Medal01 Sandia National 1 PAGE 1 OF2 AMENDMENTNLUF1 82 Se elBabcockMI54

  10. Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155

    SciTech Connect (OSTI)

    Pu, Jun [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Bai, Danna [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Cardiology, 323 Hospital of PLA, Xi'an 710054 (China); Yang, Xia [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of Teaching and Medical Administration, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China); Lu, Xiaozhao [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Xu, Lijuan, E-mail: 13609296272@163.com [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China)] [Department of Nephrology, The 323 Hospital of PLA, Xi'an 710054 (China); Lu, Jianguo, E-mail: lujianguo029@yahoo.com.cn [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)] [Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an 710038 (China)

    2012-11-16

    Highlights: Black-Right-Pointing-Pointer Adrenaline increases colon cancer cell proliferation and its resistance to cisplatin. Black-Right-Pointing-Pointer Adrenaline activates NF{kappa}B in a dose dependent manner. Black-Right-Pointing-Pointer NF{kappa}B-miR-155 pathway contributes to cell proliferation and resistance to cisplatin. -- Abstract: Recently, catecholamines have been described as being involved in the regulation of cancer genesis and progression. Here, we reported that adrenaline increased the cell proliferation and decreased the cisplatin induced apoptosis in HT29 cells. Further study found that adrenaline increased miR-155 expression in an NF{kappa}B dependent manner. HT29 cells overexpressing miR-155 had a higher cell growth rate and more resistance to cisplatin induced apoptosis. In contrast, HT29 cells overexpressing miR-155 inhibitor displayed decreased cell proliferation and sensitivity to cisplatin induced cell death. In summary, our study here revealed that adrenaline-NF{kappa}B-miR-155 pathway at least partially contributes to the psychological stress induced proliferation and chemoresistance in HT29 cells, shedding light on increasing the therapeutic strategies of cancer chemotherapy.

  11. Local and global statistical distances are equivalent on pure states

    E-Print Network [OSTI]

    Scott M. Cohen

    2009-06-10

    The statistical distance between pure quantum states is obtained by finding a measurement that is optimal in a sense defined by Wootters. As such, one may expect that the statistical distance will turn out to be different if the set of possible measurements is restricted in some way. It nonetheless turns out that if the restriction is to local operations and classical communication (LOCC) on any multipartite system, then the statistical distance is the same as it is without restriction, being equal to the angle between the states in Hilbert space.

  12. Microwave-driven ultraviolet light sources

    DOE Patents [OSTI]

    Manos, Dennis M. (Williamsburg, VA); Diggs, Jessie (Norfolk, VA); Ametepe, Joseph D. (Roanoke, VA)

    2002-01-29

    A microwave-driven ultraviolet (UV) light source is provided. The light source comprises an over-moded microwave cavity having at least one discharge bulb disposed within the microwave cavity. At least one magnetron probe is coupled directly to the microwave cavity.

  13. Krypton Fluoride Laser Driven Inertial Fusion Energy

    E-Print Network [OSTI]

    for Inertial Confinement Fusion Energy Systems San Ramon CA January 29, 2011 presented by John Sethian1 Krypton Fluoride Laser Driven Inertial Fusion Energy Presented to NAS Committee on the Prospects POWER PLANT: Attractive Technology #12;6 Outline S. ObenschainVision of R&D path to Inertial Fusion

  14. Data Driven Analysis in Transportation Systems

    E-Print Network [OSTI]

    Shahabi, Cyrus

    lines indicate where measures by TTI equal measures by IMSC. Total number of data points in each table1 Data Driven Analysis in Transportation Systems http://imsc.usc.edu/ Ugur Demiryurek, Ph studies #12;5 Rethinking Congestion · The reports are static (quarterly) · Corridors have very different

  15. WAVE-DRIVEN SURFACE FROM HF RADAR

    E-Print Network [OSTI]

    Miami, University of

    FEATURE INTERNAL CURRENTS WAVE-DRIVEN SURFACE FROM HF RADAR By Lynn K. Shay Observations from recent experiments · . . have revealed internal wave signatures. SURFACE CURRENTobservations from high oscillations are within the inter- nal wave continuum from the buoyancy to the in- ertial frequencies

  16. Longer View The Road Less Driven

    E-Print Network [OSTI]

    Handy, Susan L.

    Longer View The Road Less Driven Susan Handy I n September 2005, Hurricane Katrina slammed into New.S. Department of Energy [DOE], 2005a), a level unseen in inflation-adjusted terms even at the peak of the late 1970s energy crisis (DOE, 2005b). Shortages in the gasoline supply occurred temporarily in many parts

  17. Entrainment and Chaos in Driven Oscillators

    E-Print Network [OSTI]

    Lin, Kevin K.

    Entrainment and Chaos in Driven Oscillators Kevin K. Lin http://www.cims.nyu.edu/klin Courant-Young]. Assuming [1-3], kick amplitude A & period T which make oscillator 1. Entrained (Poincar´e map has sinks) 2. Transient chaos = entrainment + horseshoe 3. Persistent chaos: sensitive to initial conditions strange

  18. Minimum Distance between Bent and 1-resilient Boolean Functions

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    , INDIA. soumen@iitg.ernet.in 2 Applied Statistics Unit, Indian Statistical Institute, 203, B T Road, Kolkata 700 108, INDIA subho@isical.ac.in Abstract. In this paper we study the minimum distance between

  19. Distance determination to eight galaxies using expanding photosphere method

    SciTech Connect (OSTI)

    Bose, Subhash; Kumar, Brijesh, E-mail: email@subhashbose.com, E-mail: bose@aries.res.in [Aryabhatta Research Institute of Observational Sciences, Manora Peak, Nainital 263002 (India)

    2014-02-20

    Type IIP supernovae (SNe) are recognized as independent extragalactic distance indicators; however, keeping in mind the diverse nature of their observed properties as well as the availability of good quality data, more and newer events need to be tested for their applicability as reliable distance indicators. We use early photometric and spectroscopic data of eight Type IIP SNe to derive distances to their host galaxies by using the expanding photosphere method (EPM). For five of these, the EPM is applied for the first time. In this work, we improved EPM application by using SYNOW estimated velocities and by semi-deconvolving the broadband filter responses while deriving color temperatures and blackbody angular radii. We find that the derived EPM distances are consistent with that derived using other redshift-independent methods.

  20. The solar neighborhood. XXXV. Distances to 1404 M dwarf systems...

    Office of Scientific and Technical Information (OSTI)

    solar neighborhood. XXXV. Distances to 1404 M dwarf systems within 25 PC in the southern sky Winters, Jennifer G.; Jao, Wei-Chun; Dieterich, Sergio B., E-mail:...

  1. Distance sampling and the challenge of monitoring butterfly populations

    E-Print Network [OSTI]

    Shuker, David

    Distance sampling and the challenge of monitoring butterfly populations Nick J. B. Isaac110 5DD, UK; 5 Institute for Environment, Sustainability and Regeneration, Mellor Building Monitoring Scheme (UKBMS) have been influential in informing our understanding of environmental change

  2. TOWARD THE MINIMUM INNER EDGE DISTANCE OF THE HABITABLE ZONE

    E-Print Network [OSTI]

    Zsom, Andras

    We explore the minimum distance from a host star where an exoplanet could potentially be habitable in order not to discard close-in rocky exoplanets for follow-up observations. We find that the inner edge of the Habitable ...

  3. Distance Learning and the WorldWide Web

    E-Print Network [OSTI]

    Meyer, Albert R.

    /Singapore Distance Learning Project Develop and teach three courses at National University of Singapore and Nanyang. Applied research and development: Support for continuing improvement in education. Daedalus, Fall 1998, p

  4. A GPS Pseudorange Based Cooperative Vehicular Distance Measurement Technique

    E-Print Network [OSTI]

    Yang, Daiqin

    Accurate vehicular localization is important for various cooperative vehicle safety (CVS) applications such as collision avoidance, turning assistant, etc. In this paper, we propose a cooperative vehicular distance measurement ...

  5. Authoring and Presentation Tools for Distance Learning over Interactive TV

    E-Print Network [OSTI]

    Erdem, Cigdem Eroglu

    questions into interactive exams, and a virtual teacher whose facial animation is automatically generated]: Multimedia Information Systems ­ animations, evaluation/methodology, video. General Terms Management, Design, Human Factors. Keywords Distance education, interactive TV, set-top-box, multimedia presentation. 1

  6. Upper bounds on minimum distance of nonbinary quantum stabilizer codes 

    E-Print Network [OSTI]

    Kumar, Santosh

    2005-11-01

    The most popular class of quantum error correcting codes is stabilizer codes. Binary quantum stabilizer codes have been well studied, and Calderbank, Rains, Shor and Sloane (July 1998) have constructed a table of upper bounds on the minimum distance...

  7. Cepheid Variables in M33 and the Extragalactic Distance Scale 

    E-Print Network [OSTI]

    Bradshaw, Andrew K.

    2010-01-16

    , they can be used to determine distances to nearby galaxies and calibrate secondary distance indicators, such as type Ia supernovae. A detailed study of Cepheids in nearby galaxies is required in order to properly characterize their properties and variations... be related to other more fundamental quantities. The name ?variable star? can refer to a wide variety of objects, including supernovae, eclipsing binary stars, or even transiting planets. However, this thesis will be focused on a speci c type of variable star...

  8. Assessment of radiological releases from the NuMI facility during MINOS and NOvA operations

    SciTech Connect (OSTI)

    Martens, Mike; /Fermilab

    2007-04-01

    This report makes projections of the radiological releases from the NuMI facility during operations for the MINOS and NO ?A experiments. It includes an estimate of the radionuclide levels released into the atmosphere and the estimated tritium and sodium-22 concentrations in the NuMI sump water and Fermilab pond system. The analysis was performed for NuMI operations with a beam power on target increased from the present 400 kW design up to a possible 1500 kW with future upgrades. The total number of protons on target was assumed to be 18 x 10{sup 20} after the completion of MINOS and 78 x 10{sup 20} after the completion of NO ?A.

  9. The MiMeS Survey of Magnetism in Massive Stars: Introduction and overview

    E-Print Network [OSTI]

    Wade, G A; Alecian, E; Grunhut, J H; Petit, V; de Batz, B; Bohlender, D A; Cohen, D H; Henrichs, H F; Kochukhov, O; Landstreet, J D; Manset, N; Martins, F; Mathis, S; Oksala, M E; Owocki, S P; Rivinius, Th; Shultz, M E; Sundqvist, J O; Townsend, R H D; ud-Doula, A; Bouret, J -C; Braithwaite, J; Briquet, M; Carciofi, A C; David-Uraz, A; Folsom, C P; Fullerton, A W; Leroy, B; Marcolino, W L F; Moffat, A F J; Nazé, Y; Aurière, M; Bagnulo, S; Bailey, J D; Barbá, R H; Blazère, A; Böhm, T; Catala, C; Donati, J -F; Ferrario, L; Harrington, D; Howarth, I D; Ignace, R; Kaper, L; Lüftinger, T; Prinja, R; Vink, J S; Weiss, W W; Yakunin, I

    2015-01-01

    The MiMeS project is a large-scale, high resolution, sensitive spectropolarimetric investigation of the magnetic properties of O and early B type stars. Initiated in 2008 and completed in 2013, the project was supported by 3 Large Program allocations, as well as various programs initiated by independent PIs and archival resources. Ultimately, over 4800 circularly polarized spectra of 560 O and B stars were collected with the instruments ESPaDOnS at the Canada-France-Hawaii Telescope, Narval at the T\\'elescope Bernard Lyot, and HARPSpol at the European Southern Observatory La Silla 3.6m telescope, making MiMeS by far the largest systematic investigation of massive star magnetism ever undertaken. In this paper, the first in a series reporting the general results of the survey, we introduce the scientific motivation and goals, describe the sample of targets, review the instrumentation and observational techniques used, explain the exposure time calculation designed to provide sensitivity to surface dipole fields...

  10. Upgrade of the Minos+ Experiment Data Acquisition for the High Energy NuMI Beam Run

    E-Print Network [OSTI]

    William Badgett; Steve R. Hahn; Donatella Torretta; Jerry Meier; Jeffrey Gunderson; Denise Osterholm; David Saranen

    2015-06-06

    The Minos+ experiment is an extension of the Minos experiment at a higher energy and more intense neutrino beam, with the data collection having begun in the fall of 2013. The neutrino beam is provided by the Neutrinos from the Main Injector (NuMI) beam-line at Fermi National Accelerator Laboratory (Fermilab). The detector apparatus consists of two main detectors, one underground at Fermilab and the other in Soudan, Minnesota with the purpose of studying neutrino oscillations at a base line of 735 km. The original data acquisition system has been running for several years collecting data from NuMI, but with the extended run from 2013, parts of the system needed to be replaced due to obsolescence, reliability problems, and data throughput limitations. Specifically, we have replaced the front-end readout controllers, event builder, and data acquisition computing and trigger processing farms with modern, modular and reliable devices with few single points of failure. The new system is based on gigabit Ethernet TCP/IP communication to implement the event building and concatenation of data from many front-end VME readout crates. The simplicity and partitionability of the new system greatly eases the debugging and diagnosing process. The new system improves throughput by about a factor of three compared to the old system, up to 800 megabits per second, and has proven robust and reliable in the current run.

  11. SBF Distances to Leo and Virgo using the HST

    E-Print Network [OSTI]

    P. W. Morris; T. Shanks

    1998-02-05

    We have used archive HST WFPC2 data for three elliptical galaxies (NGC 3379 in the Leo I group, and NGC 4472 and NGC 4406 in the Virgo cluster) to determine their distances using the Surface Brightness Fluctuation (SBF) method as described by Tonry and Schneider (1988). A comparison of the HST results with the SBF distance moduli of Ciardullo et al (1993) shows significant disagreement and suggests that the r.m.s. error on these ground-based distance moduli is actually as large as +-0.25 mag. The agreement is only slightly improved when we compare our results with the HST and ground-based SBF distances from Ajhar et al (1997) and Tonry et al (1997); the comparison suggests that a lower limit on the error of the HST SBF distance moduli is +-0.17 mag. Overall, these results suggest that previously quoted measurement errors may underestimate the true error in SBF distance moduli by at least a factor of 2-3.

  12. DEVELOPMENT OF SOLAR DRIVEN ABSORPTION AIR CONDITIONERS AND HEAT PUMPS

    E-Print Network [OSTI]

    Dao, K.

    2013-01-01

    AIR CONDITIONERS AND HEAT PUMPS K. Dao, M. Wahlig, E. Wali,are liquid paths. DM: multistage pump driver, driven by highvapor. DW: main circulation pump driven by strong absorbent.

  13. Simulation of E-Cloud Driven Instability And Its Attenuation...

    Office of Scientific and Technical Information (OSTI)

    Simulation of E-Cloud Driven Instability And Its Attenuation Using a Feedback System in the CERN SPS Citation Details In-Document Search Title: Simulation of E-Cloud Driven...

  14. INERTIAL FUSION DRIVEN BY INTENSE HEAVY-ION BEAMS

    E-Print Network [OSTI]

    Sharp, W. M.

    2011-01-01

    HIFAN 1830 INERTIAL FUSION DRIVEN BY INTENSE HEAVY-ION BEAMSAC02-05CH11231. INERTIAL FUSION DRIVEN BY INTENSE HEAVY-ION467 (1992). [38] R. W. Moir, Fusion Tech. 25, 5 (1994) [39

  15. Verification Testing Test Driven Development Testing with JUnit Verification

    E-Print Network [OSTI]

    Peters, Dennis

    Verification Testing Test Driven Development Testing with JUnit Verification Any activity should be verified. #12;Verification Testing Test Driven Development Testing with JUnit Approaches to verification 1 Testing 2 Static Analysis · Peer review · Insepction/Walk-through/Structured review · Formal

  16. Energy-Driven Pattern Formation Robert V. Kohn

    E-Print Network [OSTI]

    Energy-Driven Pattern Formation Robert V. Kohn Grad Student and Postdoc Seminar April 22, 2011 Robert V. Kohn Energy-Driven Pattern Formation #12;Overview What is energy-driven pattern formation? Hard by singular perturbation Statics: minimum energy scaling laws Dynamics: patterns induced by steepest

  17. DemandDriven Type Inference with Subgoal Pruning

    E-Print Network [OSTI]

    Tobin-Hochstadt, Sam

    Demand-Driven Type Inference with Subgoal Pruning: Trading Precision for Scalability S. Alexander, but no further. For larger programs, this paper proposes using a kind of demand-driven analysis where the number pro- poses modifying existing algorithms in two ways: (1) make them demand-driven, and (2) make them

  18. DRIVEN PIPE PILES IN DENSE SAND BYRON BYRNE

    E-Print Network [OSTI]

    Byrne, Byron

    DRIVEN PIPE PILES IN DENSE SAND BYRON BYRNE GEOMECHANICS GROUP THE UNIVERSITY OF WESTERN AUSTRALIA #12;Driven Pipe Piles in Dense Sand Byron Byrne Geomechanics Group The University of Western Australia #12;Driven Pipe Piles in Dense Sand Byron Byrne Geomechanics Group The University of Western Australia

  19. Accelerator Driven System Target Requirements and R&D

    E-Print Network [OSTI]

    McDonald, Kirk

    Accelerator Driven System Target Requirements and R&D Stuart Henderson Fermilab January 13, 2012 #12;Accelerator Driven Systems High-power, highly reliable proton accelerator · ~1 GeV beam energy and target technology for Accelerator-Driven Systems (ADS) · The White Paper was intended to make a hard

  20. Inherent shutdown capabilities in accelerator-driven systems

    E-Print Network [OSTI]

    Inherent shutdown capabilities in accelerator-driven systems M. Erikssona, *, J.E. Cahalanb a Royal Abstract The applicability for inherent shutdown mechanisms in accelerator-driven systems (ADS) has been. In this paper, we explore the use of passive safety mechanisms to accelerator- driven systems (ADS). While

  1. Current-Driven Filament Instabilities in Relativistic Plasmas. Final report

    SciTech Connect (OSTI)

    Chuang Ren

    2013-02-13

    This grant has supported a study of some fundamental problems in current- and flow-driven instabilities in plasmas and their applications in inertial confinement fusion (ICF) and astrophysics. It addressed current-driven instabilities and their roles in fast ignition, and flow-driven instabilities and their applications in astrophysics.

  2. Model-Driven Business Process Recovery , Terence C. Lau2

    E-Print Network [OSTI]

    Zou, Ying

    Model-Driven Business Process Recovery Ying Zou1 , Terence C. Lau2 , Kostas Kontogiannis3 , Tack. In this paper, we propose a model-driven business process recovery framework that captures the essential-to-date linkage between business tasks and their implementation in source code, we propose a model-driven business

  3. cis-and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary Metabolites in Two Arabidopsis

    E-Print Network [OSTI]

    Tholl, Dorothea

    involved in secondary metabolite biosynthetic pathways that are inducible by a fungal elicitor, alamethicin and secondary metabolite profiles. We suggest that cis- and trans-regulation of miRNA and other genes providescis- and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary

  4. Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

    SciTech Connect (OSTI)

    Zhang, Jian, E-mail: zhangjian197011@yahoo.com [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Zhang, Tao [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Ti, Xinyu; Shi, Jieran; Wu, Changgui; Ren, Xinling [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [Department of Respiratory Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China); Yin, Hong, E-mail: yinnhong@yahoo.com [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)] [The Medical Image Center, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032 (China)

    2010-08-13

    Research highlights: {yields} Curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells {yields} Curcumin promotes apoptosis in A549/DDP cells through a miRNA signaling pathway {yields} Curcumin induces A549/DDP cell apoptosis by downregulating miR-186* {yields} miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin -- Abstract: Curcumin extracted from the rhizomes of Curcuma longa L. has been shown to have inhibitory effects on cancers through its anti-proliferative and pro-apoptotic activities. Emerging evidence demonstrates that curcumin can overcome drug resistance to classical chemotherapies. Thus, the mechanisms underlying the anti-tumor activities of curcumin require further study. In our study, we first demonstrated that curcumin had anti-cancer effects on A549/DDP multidrug-resistant human lung adenocarcinoma cells. Further studies showed that curcumin altered miRNA expression; in particular, significantly downregulated the expression of miR-186* in A549/DDP. In addition, transfection of cells with a miR-186* inhibitor promoted A549/DDP apoptosis, and overexpression of miR-186* significantly inhibited curcumin-induced apoptosis in A549/DDP cells. These observations suggest that miR-186* may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin.

  5. miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2

    SciTech Connect (OSTI)

    Zhou, Jing; Tian, Ye; Li, Juan; Lu, Binbin; Sun, Ming; Zou, Yanfen; Kong, Rong; Luo, Yanhong; Shi, Yongguo; Wang, Keming; Ji, Guozhong

    2013-04-05

    Highlights: ? miR-206 was downexpressed in tumor samples compared with matched normal samples. ? Enhanced expression of miR-206 could inhibit breast cancer growth in vitro. ? Luciferase confirmed miR-206 functions as an anti-oncogene by targeting cyclinD2. ? A reverse correlation between miR-206 and cyclinD2 in breast cancer was found. -- Abstract: MicroRNAs act as important gene regulators in human genomes, and their aberrant expression is linked to many malignancies. Aberrant expression of miR-206 has been frequently reported in cancer studies; however, the role and mechanism of its function in breast cancer remains unclear. Quantitative real-time PCR was performed to detect the relative expression levels of miR-206 in breast cancer and normal breast tissues. Lower expression of miR-206 in breast cancer tissues was associated with larger tumour size and a more advanced clinical stage. Further in vitro observations showed that the enforced expression of miR-206 in MCF-7 breast cancer cells inhibited cell growth by blocking the G1/S transition and suppressed cell proliferation and colony formation, implying that miR-206 functions as a tumour suppressor in the progression of breast cancer. Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3?-untranslated region of cyclinD2 mRNA. qRT-PCR and Western blot assays verified that miR-206 reduced cyclinD2 expression at both the mRNA and protein levels. A reverse correlation between miR-206 and cyclinD2 expression was noted in breast cancer tissues. Altogether, our results identify a crucial tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclinD2, and suggest that miR-206 might be a candidate prognostic predictor or an anticancer therapeutic target for breast cancer patients.

  6. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  7. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 If this form

  8. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3

  9. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone Number 3

  10. NUEX16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 Student

  11. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My Requirements" 3

  12. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www Warren · Detroit, MI 48202-0340 If this form is required it will be listed in Pipeline, under "My

  13. Manuscript was received April 15, 2007. Irina Hossain is with the Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651-

    E-Print Network [OSTI]

    Mahmud, Syed Masud

    and Computer Engineering, Wayne State University, Detroit, MI. Phone: 651-815-5828; Fax: 651- 305-4549; e State University, Detroit, MI. Phone: 313-577-3855; Fax: 313-577-5845; e-mail: smahmud

  14. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Warren · Detroit, MI 48202-0340 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  15. CTFS16 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU Student ID # Student's Last Name Phone

  16. VRHS14 Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www: OFFICE OF STUDENT FINANCIAL AID · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI

  17. Wind-Driven Currents The first, and simplest, theory of steady wind-driven flow is due to Ekman

    E-Print Network [OSTI]

    Griesel, Alexa

    Wind-Driven Currents The first, and simplest, theory of steady wind-driven flow is due to Ekman gradients are negligible. The goal of this project is to isolate the wind-driven flow using the FASINEX moored measurements of velocity and wind stress. 1. Writing u Uei t = , and assuming a parameterization

  18. A signature for turbulence driven magnetic islands

    SciTech Connect (OSTI)

    Agullo, O.; Muraglia, M.; Benkadda, S. [Aix-Marseille Université, CNRS, PIIM, UMR 7345 Marseille (France); France-Japan Magnetic Fusion Laboratory, LIA 336 CNRS, Marseille (France); Poyé, A. [Univ. Bordeaux, CNRS, CEA, CELIA (Centre Lasers Intenses et Applications), UMR 5107, F-33405 Talence (France); Yagi, M. [Plasma Theory and Simulation Gr., JAEA, Rokkasho (Japan); Garbet, X. [IRFM, CEA, St-Paul-Lez-Durance 13108 (France); Sen, A. [Institute for Plasma Research, Bhat, Gandhinagar 382428 (India)

    2014-09-15

    We investigate the properties of magnetic islands arising from tearing instabilities that are driven by an interchange turbulence. We find that such islands possess a specific signature that permits an identification of their origin. We demonstrate that the persistence of a small scale turbulence maintains a mean pressure profile, whose characteristics makes it possible to discriminate between turbulence driven islands from those arising due to an unfavourable plasma current density gradient. We also find that the island poloidal turnover time, in the steady state, is independent of the levels of the interchange and tearing energy sources. Finally, we show that a mixing length approach is adequate to make theoretical predictions concerning island flattening in the island rotation frame.

  19. Distances to Galactic high-velocity clouds. Complex C

    E-Print Network [OSTI]

    B. P. Wakker; D. G. York; J. C. Howk; J. C. Barentine; R. Wilhelm; R. F. Peletier; H. van Woerden; T. C. Beers; Z. Ivezic; P. Richter; U. J. Schwarz

    2007-10-17

    We report the first determination of a distance bracket for the high-velocity cloud (HVC) complex C. Combined with previous measurements showing that this cloud has a metallicity of 0.15 times solar, these results provide ample evidence that complex C traces the continuing accretion of intergalactic gas falling onto the Milky Way. Accounting for both neutral and ionized hydrogen as well as He, the distance bracket implies a mass of 3-14x10^6 M_sun, and the complex represents a mass inflow of 0.1-0.25 M_sun/yr. We base our distance bracket on the detection of CaII absorption in the spectrum of the blue horizontal branch star SDSS J120404.78+623345.6, in combination with a significant non-detection toward the BHB star BS 16034-0114. These results set a strong distance bracket of 3.7-11.2 kpc on the distance to complex C. A more weakly supported lower limit of 6.7 kpc may be derived from the spectrum of the BHB star BS 16079-0017.

  20. Time-delay Cosmography: Increased Leverage with Angular Diameter Distances

    E-Print Network [OSTI]

    Jee, Inh; Suyu, Sherry H; Huterer, Dragan

    2015-01-01

    Strong lensing time-delay systems constrain cosmological parameters via the so-called time-delay distance and the angular diameter distance to the lens. In previous studies, only the former information was used. In this paper, we show that the cosmological constraints improve significantly when the latter information is also included. Specifically, the angular diameter distance plays a crucial role in breaking the degeneracy between the curvature of the Universe and the time-varying equation of state of dark energy. Using a mock sample of 55 bright quadruple lens systems based on expectations for ongoing/future imaging surveys, we find that adding the angular diameter distance information to the time-delay distance information and the cosmic microwave background data of Planck improves the constraint on the constant equation of state by 30%, on the time variation in the equation of state by a factor of two, and on the Hubble constant in the flat $\\Lambda$CDM model by a factor of two. Therefore, previous forec...

  1. ac-driven atomic quantum motor

    E-Print Network [OSTI]

    A. V. Ponomarev; S. Denisov; P. Hanggi

    2009-06-09

    We invent an ac-driven quantum motor consisting of two different, interacting ultracold atoms placed into a ring-shaped optical lattice and submerged in a pulsating magnetic field. While the first atom carries a current, the second one serves as a quantum starter. For fixed zero-momentum initial conditions the asymptotic carrier velocity converges to a unique non-zero value. We also demonstrate that this quantum motor performs work against a constant load.

  2. Electrically Driven Technologies for Radioactive Aerosol Abatement

    SciTech Connect (OSTI)

    David W. DePaoli; Ofodike A. Ezekoye; Costas Tsouris; Valmor F. de Almeida

    2003-01-28

    The purpose of this research project was to develop an improved understanding of how electriexecy driven processes, including electrocoalescence, acoustic agglomeration, and electric filtration, may be employed to efficiently treat problems caused by the formation of aerosols during DOE waste treatment operations. The production of aerosols during treatment and retrieval operations in radioactive waste tanks and during thermal treatment operations such as calcination presents a significant problem of cost, worker exposure, potential for release, and increased waste volume.

  3. Chaos control of parametric driven Duffing oscillators

    SciTech Connect (OSTI)

    Jin, Leisheng; Mei, Jie; Li, Lijie, E-mail: L.Li@swansea.ac.uk [College of Engineering, Swansea University, Swansea SA2 8PP (United Kingdom)

    2014-03-31

    Duffing resonators are typical dynamic systems, which can exhibit chaotic oscillations, subject to certain driving conditions. Chaotic oscillations of resonating systems with negative and positive spring constants are identified to investigate in this paper. Parametric driver imposed on these two systems affects nonlinear behaviours, which has been theoretically analyzed with regard to variation of driving parameters (frequency, amplitude). Systematic calculations have been performed for these two systems driven by parametric pumps to unveil the controllability of chaos.

  4. Wave-driven Countercurrent Plasma Centrifuge

    SciTech Connect (OSTI)

    A.J. Fetterman and N.J. Fisch

    2009-03-20

    A method for driving rotation and a countercurrent flow in a fully ionized plasma centrifuge is described. The rotation is produced by radiofrequency waves near the cyclotron resonance. The wave energy is transferred into potential energy in a manner similar to the ? channeling effect. The countercurrent flow may also be driven by radiofrequency waves. By driving both the rotation and the flow pattern using waves instead of electrodes, physical and engineering issues may be avoided.

  5. Proposed Laser-driven, Dielectric Microstructure Few-cm Long Undulator for Attosecond Coherent X-rays

    SciTech Connect (OSTI)

    Plettner, T; Byer, R.L.; /Stanford U., Ginzton Lab.

    2011-09-16

    This article presents the concept of an all-dielectric laser-driven undulator for the generation of coherent X-rays. The proposed laser-driven undulator is expected to produce internal deflection forces equivalent to a several-Tesla magnetic field acting on a speed-of-light particle. The key idea for this laser-driven undulator is its ability to provide phase synchronicity between the deflection force and the electron beam for a distance that is much greater than the laser wavelength. The potential advantage of this undulator is illustrated with a possible design example that assumes a small laser accelerator which delivers a 2 GeV, 1 pC, 1 kHz electron bunch train to a 10 cm long, 1/2 mm period laser-driven undulator. Such an undulator could produce coherent X-ray pulses with {approx}10{sup 9} photons of 64 keV energy. The numerical modeling for the expected X-ray pulse shape was performed with GENESIS, which predicts X-ray pulse durations in the few-attosecond range. Possible applications for nonlinear electromagnetic effects from these X-ray pulses are briefly discussed.

  6. Driven Wild: How the Fight Against Automobiles Launched the Modern Wilderness Movement

    E-Print Network [OSTI]

    Sowards, Adam M.

    2003-01-01

    Driven Wild: How the Fight Against Automobiles Launched theDriven Wild: How the Fight Against Automobiles Launched the

  7. Evidence against correlations between nuclear decay rates and Earth-Sun distance

    E-Print Network [OSTI]

    Norman, Eric B.

    2009-01-01

    distance of the source to the Sun. This work was supportedNuclear Decay Rates and Earth-Sun Distance Eric B. Normanand 241 Am and the Earth-Sun distance. We find no evidence

  8. How Pseudo-Boolean Programming can help Genome Rearrangement Distance Computation

    E-Print Network [OSTI]

    Fertin, Guillaume

    How Pseudo-Boolean Programming can help Genome Rearrangement Distance Computation S vialette@lri.fr Abstract. Computing genomic distances between whole genomes is a fundamental problem in comparative genomics. Recent researches have resulted in different genomic distance definitions: number

  9. Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor

    E-Print Network [OSTI]

    Gerstein, Mark

    Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor targets predicted by sequence-alignment databases and the relative low accuracy of such predictions which with tumor progression in squamous cell carcinoma of the head and neck (HNSCC). We further demonstrate

  10. Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1

    E-Print Network [OSTI]

    Sheffield, University of

    Corrosion mechanisms of low level vitrified radioactive waste in a loamy soil M.I. Ojovan1 , W-sodium content radioactive waste borosilicate glass buried in a loamy soil (glass K-26) and in an open testing. This mechanism is likely to remain dominant until the decay of 137 Cs in the glass is below exemption levels

  11. A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development

    E-Print Network [OSTI]

    Ito, Mitsuteru; Sferruzzi-Perri, Amanda N.; Edwards, Carol A.; Adalsteinsson, Bjorn T.; Allen, Sarah E.; Loo, Tsui-Han; Kitazawa, Moe; Kaneko-Ishino, Tomoko; Ishino, Fumitoshi; Stewart, Colin L.; Ferguson-Smith, Anne C.

    2015-07-02

    ability of small molecules like oxygen to transfer by passive diffusion from mother to fetus (Laga et al., 1973). The TDC and SDC values of the mutant placentae indicate that ?miR-127 mice have a higher diffusive capacity than WTs and conversely...

  12. THE DARK SIDE OF SECURITY BY OBSCURITY and Cloning MiFare Classic Rail and Building Passes, Anywhere, Anytime

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    , Anywhere, Anytime Nicolas T. Courtois University College London, Computer Science, Gower street, WC1E 6BT, London, UK Keywords: Access control, RFID, contactless smart cards, MiFare Classic, London Oyster card- wide and in public transportation. For more than 10 years the specification of these cards was kept

  13. A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1

    E-Print Network [OSTI]

    Southern California, University of

    A note on tsunami amplitudes above submarine slides and slumps M.I. Todorovska*, A. Hayir1 , M 2531, Los Angeles, CA 90089-2531, USA Accepted 27 October 2001 Abstract Tsunami generated by submarine functions. Tsunami waveforms for these models are computed using linearized shallow water theory

  14. The PEANUT experiment in the NuMI beam at Fermilab

    SciTech Connect (OSTI)

    Russo, A. [Dipartimento di Scienze Fisiche, Universita Federico II di Napoli, 80125 Napoli (Italy)

    2010-03-30

    The PEANUT experiment was designed to study neutrino interactions in the few GeV range using the NuMI beam at Fermilab. The detector uses a hybrid technique, being made of nuclear emulsions and scintillator trackers. Emulsion films act as a tracking device and they are interleaved with lead plates used as neutrino targets. The detector is designed to reconstruct the topology of neutrino interactions at the single particle level. We present here the full reconstruction and analysis of a sample of 147 neutrino interactions that occurred in the PEANUT detector and the measurement of the quasielastic, resonance and deep-inelastic contributions to the total charged-current cross section. This technique could be applied for the beam monitoring at future neutrino facilities.

  15. The Hubble Constant from the Fornax Cluster Distance

    E-Print Network [OSTI]

    Tom Richtler; Georg Drenkhahn; Matias Gomez; Wilhelm Seggewiss

    1999-05-17

    Type Ia supernovae are the best cosmological standard candles available. The intrinsic scatter of their decline-rate- and colour-corrected peak brightnesses in the Hubble diagram is within observational error limits, corresponding to an uncertainty of only 3km/s/Mpc of the Hubble constant. Any additional uncertainty, resulting from peak-brightness calibration, must be kept small by measuring distances to nearby host galaxies most precisely. A number of different distance determinations of the Fornax cluster of galaxies agree well on a distance modulus of 31.35+-0.04mag (18.6+-0.3Mpc). This leads to accurate absolute magnitudes of the well-observed Fornax type Ia SNe SN1980N, SN1981D, and SN1992A and finally to a Hubble constant of H_0=72+-6km/s/Mpc.

  16. Exploring the Graph of Graphs: Network Evolution and Centrality Distances

    E-Print Network [OSTI]

    Pignolet, Yvonne Anne; Schmid, Stefan; Tredan, Gilles

    2015-01-01

    The topological structure of complex networks has fascinated researchers for several decades, and today we have a fairly good understanding of the types and reoccurring characteristics of many different complex networks. However, surprisingly little is known today about models to compare complex graphs, and quantitatively measure their similarity and dynamics. In the past a variety of node centralities, i.e., functions which assign values to nodes to represent their importance in the graph. Based on such centralities we propose a natural similarity measure for complex networks: the centrality distance $d_C$, the difference between two graphs with respect to a given node centrality $C$. Centrality distances can take the specific roles of the different nodes in the network into account, and have many interesting applications. As a case study, we investigate the evolution of networks with respect to centrality distances and their approximations based on closeness, betweenness, pagerank, clustering and degree cen...

  17. Validation of the MCNPX-PoliMi Code to Design a Fast-Neutron Multiplicity Counter

    SciTech Connect (OSTI)

    J. L. Dolan; A. C. Kaplan; M. Flaska; S. A. Pozzi; D. L. Chichester

    2012-07-01

    Many safeguards measurement systems used at nuclear facilities, both domestically and internationally, rely on He-3 detectors and well established mathematical equations to interpret coincidence and multiplicity-type measurements for verifying quantities of special nuclear material. Due to resource shortages alternatives to these existing He-3 based systems are being sought. Work is also underway to broaden the capabilities of these types of measurement systems in order to improve current multiplicity analysis techniques. As a part of a Material Protection, Accounting, and Control Technology (MPACT) project within the U.S. Department of Energy's Fuel Cycle Technology Program we are designing a fast-neutron multiplicity counter with organic liquid scintillators to quantify important quantities such as plutonium mass. We are also examining the potential benefits of using fast-neutron detectors for multiplicity analysis of advanced fuels in comparison with He-3 detectors and testing the performance of such designs. The designs are being developed and optimized using the MCNPX-PoliMi transport code to study detector response. In the full paper, we will discuss validation measurements used to justify the use of the MCNPX-PoliMi code paired with the MPPost multiplicity routine to design a fast neutron multiplicity counter with liquid scintillators. This multiplicity counter will be designed with the end goal of safeguarding advanced nuclear fuels. With improved timing qualities associated with liquid scintillation detectors, we can design a system that is less limited by nuclear materials of high activities. Initial testing of the designed system with nuclear fuels will take place at Idaho National Laboratory in a later stage of this collaboration.

  18. T-1025 IU SciBath-768 detector tests in MI-12

    SciTech Connect (OSTI)

    Tayloe, Rex; Cooper, R.; Garrison, L.; Thornton, T.; Rebenitsch, L.; DeJongh, Fritz; Loer, Benjamin; Ramberg, Erik; Yoo, Jonghee; /Fermilab

    2012-02-11

    This is a memorandum of understanding between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Department of Physics and Center for Exploration of Energy and Matter, Indiana University, who have committed to participate in detector tests to be carried out during the 2012 Fermilab Neutrino program. The memorandum is intended solely for the purpose of recording expectations for budget estimates and work allocations for Fermilab, the funding agencies and the participating institutions. it reflects an arrangement that currently is satisfactory to the parties; however, it is recognized and anticipated that changing circumstances of the evolving research program will necessitate revisions. The parties agree to modify this memorandum to reflect such required adjustments. Actual contractual obligations will be set forth in separate documents. The experimenters propsoe to test their prototype 'SciBat-768' detector in the MI-12 building for 3 months (February-April) in Spring 2012. The major goal of this effort is to measure or limit the flux of beam-induced neutrons in a far-off-axis (> 45{sup o}) location of the Booster Neutrino Beamline (BNB). This flux is of interest for a proposed coherent neutral-current neutrino-argon elastic scattering experiment. A second goal is to collect more test data for the SciBath-768 to enable better understanding and calibration of the device. The SciBath-768 detector successfully ran for 3 months in the MINOS Underground Area in Fall 2011 as testbeam experiment T-1014 and is currently running above ground in the MINOS service building. For the run proposed here, the experiments are requesting: space in MI-12 in which to run the SciBath detector during February-April 2012 while the BNB is operating; technical support to help with moving the equipment on site; access to power, internet, and accelerator signals; and a small office space from which to run and monitor the experiment.

  19. Distance determinations to shield galaxies from Hubble space telescope imaging

    SciTech Connect (OSTI)

    McQuinn, Kristen B. W.; Skillman, Evan D. [Minnesota Institute for Astrophysics, School of Physics and Astronomy, University of Minnesota, 116 Church Street, S.E., Minneapolis, MN 55455 (United States); Cannon, John M.; Cave, Ian [Department of Physics and Astronomy, Macalester College, 1600 Grand Avenue, Saint Paul, MN 55105 (United States); Dolphin, Andrew E. [Raytheon Company, 1151 E. Hermans Road, Tucson, AZ 85756 (United States); Salzer, John J. [Department of Astronomy, Indiana University, 727 East 3rd Street, Bloomington, IN 47405 (United States); Haynes, Martha P.; Adams, Elizabeth; Giovanelli, Riccardo [Center for Radiophysics and Space Research, Space Sciences Building, Cornell University, Ithaca, NY 14853 (United States); Elson, Ed C. [Astrophysics, Cosmology and Gravity Centre (ACGC), Department of Astronomy, University of Cape Town, Private Bag X3, Rondebosch 7701 (South Africa); Ott, Juërgen [National Radio Astronomy Observatory, P.O. Box O, 1003 Lopezville Road, Socorro, NM 87801 (United States); Saintonge, Amélie, E-mail: kmcquinn@astro.umn.edu [Max-Planck-Institute for Astrophysics, D-85741 Garching (Germany)

    2014-04-10

    The Survey of H I in Extremely Low-mass Dwarf (SHIELD) galaxies is an ongoing multi-wavelength program to characterize the gas, star formation, and evolution in gas-rich, very low-mass galaxies. The galaxies were selected from the first ?10% of the H I Arecibo Legacy Fast ALFA (ALFALFA) survey based on their inferred low H I mass and low baryonic mass, and all systems have recent star formation. Thus, the SHIELD sample probes the faint end of the galaxy luminosity function for star-forming galaxies. Here, we measure the distances to the 12 SHIELD galaxies to be between 5 and 12 Mpc by applying the tip of the red giant method to the resolved stellar populations imaged by the Hubble Space Telescope. Based on these distances, the H I masses in the sample range from 4 × 10{sup 6} to 6 × 10{sup 7} M {sub ?}, with a median H I mass of 1 × 10{sup 7} M {sub ?}. The tip of the red giant branch distances are up to 73% farther than flow-model estimates in the ALFALFA catalog. Because of the relatively large uncertainties of flow-model distances, we are biased toward selecting galaxies from the ALFALFA catalog where the flow model underestimates the true distances. The measured distances allow for an assessment of the native environments around the sample members. Five of the galaxies are part of the NGC 672 and NGC 784 groups, which together constitute a single structure. One galaxy is part of a larger linear ensemble of nine systems that stretches 1.6 Mpc from end to end. Three galaxies reside in regions with 1-9 neighbors, and four galaxies are truly isolated with no known system identified within a radius of 1 Mpc.

  20. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 2015-16 Verification of 2014 Income - Student · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne

  1. Time-resolved observation of fast domain-walls driven by vertical spin currents in short tracks

    SciTech Connect (OSTI)

    Sampaio, Joao; Lequeux, Steven; Chanthbouala, Andre; Cros, Vincent; Grollier, Julie; Matsumoto, Rie; Yakushiji, Kay; Kubota, Hitoshi; Fukushima, Akio; Yuasa, Shinji; Nishimura, Kazumasa; Nagamine, Yoshinori; Maehara, Hiroki; Tsunekawa, Koji

    2013-12-09

    We present time-resolved measurements of the displacement of magnetic domain-walls (DWs) driven by vertical spin-polarized currents in track-shaped magnetic tunnel junctions. In these structures, we observe very high DW velocities (600?m/s) at current densities below 10{sup 7}?A/cm{sup 2}. We show that the efficient spin-transfer torque combined with a short propagation distance allows avoiding the Walker breakdown process and achieving deterministic, reversible, and fast (?1?ns) DW-mediated switching of magnetic tunnel junction elements, which is of great interest for the implementation of fast DW-based spintronic devices.

  2. Development of the table of initial isolation distances and protective action distances for the 2004 emergency response guidebook.

    SciTech Connect (OSTI)

    Brown, D. F.; Freeman, W. A.; Carhart, R. A.; Krumpolc, M.; Decision and Information Sciences; Univ. of Illinois at Chicago

    2005-09-23

    This report provides technical documentation for values in the Table of Initial Isolation and Protective Action Distances (PADs) in the 2004 Emergency Response Guidebook (ERG2004). The objective for choosing the PADs specified in the ERG2004 is to balance the need to adequately protect the public from exposure to potentially harmful substances against the risks and expenses that could result from overreacting to a spill. To quantify this balance, a statistical approach is adopted, whereby the best available information is used to conduct an accident scenario analysis and develop a set of up to 1,000,000 hypothetical incidents. The set accounts for differences in containers types, incident types, accident severity (i.e., amounts released), locations, times of day, times of year, and meteorological conditions. Each scenario is analyzed using detailed emission rate and atmospheric dispersion models to calculate the downwind chemical concentrations from which a 'safe distance' is determined. The safe distance is defined as the distance downwind from the source at which the chemical concentration falls below health protection criteria. The American Industrial Hygiene Association's Emergency Response Planning Guideline Level 2 (ERPG-2) or equivalent is the health criteria used. The statistical sample of safe distance values for all incidents considered in the analysis are separated into four categories: small spill/daytime release, small spill/nighttime release, large spill/daytime release, and large spill/nighttime release. The 90th-percentile safe distance values for each of these groups became the PADs that appear in the ERG2004.

  3. Online Distance Recovery for a Sewer Inspection Robot Marina Kolesnik

    E-Print Network [OSTI]

    Kolesnik, Marina

    Online Distance Recovery for a Sewer Inspection Robot Marina Kolesnik Institute for Autonomous computation based on images taken in a sewer by a robot-inspector is presented. Modern concrete sewers provide regular marks on the sewer images and can be used for their 3-D interpretation. After each robot

  4. On the White Dwarf distances to Galactic Globular Clusters

    E-Print Network [OSTI]

    M. Salaris; S. Cassisi; E. Garcia-Berro; J. Isern; S. Torres

    2001-03-20

    We analyze in detail various possible sources of systematic errors on the distances of globular clusters derived by fitting a local template DA white dwarf sequence to the cluster counterpart (the so-called WD-fitting technique). We find that the unknown thickness of the hydrogen layer of white dwarfs in clusters plays a non negligible role. For reasonable assumptions - supported by the few sparse available observational constraints - about the unknown mass and thickness of the hydrogen layer for the cluster white dwarfs, a realistic estimate of the systematic error on the distance is within +-0.10 mag. However, particular combinations of white dwarf masses and envelope thicknesses - which at present cannot be excluded a priori - could produce larger errors. Contamination of the cluster DA sequence by non-DA white dwarfs introduces a very small systematic error of about -0.03 mag in the Mv/(V-I) plane, but in the Mv/(B-V) plane the systematic error amounts to ~ +0.20 mag. Contamination by white dwarfs with helium cores should not influence appreciably the WD-fitting distances. Finally, we obtain a derivative D((m-M)v)/D(E(B-V))~ -5.5 for the WD-fitting distances, which is very similar to the dependence found when using the Main Sequence fitting technique.

  5. Defense from a distance ORNL robotics sensors detect underwater

    E-Print Network [OSTI]

    SCIENCE Defense from a distance ORNL robotics sensors detect underwater explosive ordnance Modern of the future are not human oriented, but robotics oriented. For robots to perform their mission of safety at the forefront of robotics design, these are the droids we are looking for. ­Dylan Platz Karnowski analyzes

  6. GIS IN LAND RESOURCE MANAGEMENT Distance Education Section

    E-Print Network [OSTI]

    Ma, Lena

    1 GIS IN LAND RESOURCE MANAGEMENT SWS 5721C Distance Education Section [GIS: Geographic Information, reading material, library of GIS video clips, and GIS resources) Email and discussion board are used communication): Chat sessions: Thursday 8-9 p.m. US Eastern Time. A virtual computer lab is used for GIS

  7. The breakpoint distance for signed sequences (extended abstract)

    E-Print Network [OSTI]

    Chauve, Cedric

    of reversals, insertion and deletion between two genomes, G and H with possibly multiple genes from the same the evolutionary distance between genomes in terms of gene order rearrangements has been intensively studied, from in comparative genomics [2]. From an algorithmic point, it can roughly be de#12;ned as follows: given a set

  8. Detecting VoIP Floods Using the Hellinger Distance

    E-Print Network [OSTI]

    Wang, Haining

    Detecting VoIP Floods Using the Hellinger Distance Hemant Sengar, Student Member, IEEE, Haining running over the TCP/IP suite, it is susceptible to flooding attacks. If flooded, as a time. Because multiple protocols are involved in a VoIP service and most of them are susceptible to flooding

  9. Topographic Distance Functions for Interpolation of Meteorological Data

    E-Print Network [OSTI]

    Hamann, Bernd

    Topographic Distance Functions for Interpolation of Meteorological Data Burkhard Lehner1 , Georg evapotranspiration ET0. It is usually estimated from other meteorological quantities measured at weather stations for agricultural and urban needs. Also for setting up a land use plan it can be a base for decisions. One important

  10. 75Radiation Dose and Distance This iconic photo was

    E-Print Network [OSTI]

    on March 15, a few days after the Japan 2011 earthquake, which caused severe damage to the Fukushima Press/Kyodo News) The devastating Japan 2011 earthquake damaged the nuclear reactors in Fukushima, which: Date Distance (km) Location Dose Rate (microSeiverts/hr) March 15 1 km Fukushima #2 plant 8,200 March

  11. Weighted Distance Weighted Discrimination and its Asymptotic Properties

    E-Print Network [OSTI]

    Zhang, Hao "Helen"

    and Phrases: Fisher consistency; High-dimensional, low-sample size data; Linear discrimination; Non-standard Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC 27599 4 School The Support Vector Machine (SVM) (Vapnik 1995) is a powerful classification tool. Distance Weighted

  12. Computing the minimal distance of cyclic codes Jose Felipe Voloch

    E-Print Network [OSTI]

    Voloch, Felipe

    , 0 r r and compute a table of all codewords with exactly r nonzero coordinates among its first k below. Chen produced a table of the minimal distances of binary cyclic codes of length at most 65 which shift of c with exactly r nonzero coordinates among its first k coordinates. See [CS, lemma 1

  13. THE FIRST ACCURATE PARALLAX DISTANCE TO A BLACK HOLE

    E-Print Network [OSTI]

    Miller-Jones, J. C. A.

    Using astrometric VLBI observations, we have determined the parallax of the black hole X-ray binary V404 Cyg to be 0.418 [plus or minus sign] 0.024 mas, corresponding to a distance of 2.39 [plus or minus sign] 0.14 kpc, ...

  14. TRIUMAH 2012 RESULTS MALES BY AGE * distance measured in miles

    E-Print Network [OSTI]

    Thomas, David D.

    TRIUMAH 2012 RESULTS MALES BY AGE * distance measured in miles Last Name First Name Swim Bike Run+ Ferber Warren 0.364 7.390 2.300 10.054 50+ Luther Richard 0.500 6.900 2.420 9.820 Ages Other Strom Thad 0

  15. Free Energy Surfaces from Single-Distance Information Philipp Schuetz,

    E-Print Network [OSTI]

    Caflisch, Amedeo

    Free Energy Surfaces from Single-Distance Information Philipp Schuetz, Rene´ Wuttke, Benjamin We propose a network-based method for determining basins and barriers of complex free energy surfaces for the iterative determination of individual basins by the minimum-cut-based free energy profile, a barrier

  16. Distance Estimation Using Bidirectional Communications Without Synchronous Clocking

    E-Print Network [OSTI]

    Sethares, William A.

    Estimation via Asynchronous Clocks (DEVAC) and (2) Distance Estimation via Asynchronous Phase Shift (DEVAPS a reply that acts analogously to the return of the radar. The DEVAPS method operates analogously and frequency accuracy are computed to show the limits of performance with the DEVAPS method. The analytical

  17. The Exemplar Breakpoint Distance for nontrivial genomes cannot be approximated

    E-Print Network [OSTI]

    Fertin, Guillaume

    The Exemplar Breakpoint Distance for non­trivial genomes cannot be approximated Guillaume Blin 1 ­ France guillaume.fertin@univ­nantes.fr Abstract. A promising and active field of comparative genomics con­ sists in comparing two genomes by establishing a one­to­one correspon­ dence (i.e., a matching) between

  18. Of mice and men: Algorithms for evolutionary distances

    E-Print Network [OSTI]

    Kececioglu, John

    Of mice and men: Algorithms for evolutionary distances between genomes with translocation \\Lambda is combinatorial algorithms for genome rear­ rangement. In the course of its evolution, the genome of an organism is to determine the minimum number of such events that transform one genome to another. This number is called

  19. On the Impact of Cepheid Outliers on the Distance Ladder

    E-Print Network [OSTI]

    Becker, M R; Rozo, E; Marshall, P; Rykoff, E S

    2015-01-01

    Recent work by Efstathiou (2014) highlighted the importance of outliers in the period-luminosity (PL) relation of Cepheid data on the distance ladder. We present a statistical framework designed to address this difficulty, and apply it to the Cepheid data from the Milky Way (MW), the Large Magellanic Cloud (LMC), and the Riess et al. (2011) (hereafter R11) dataset. We consider two possible models of the outlier population in the R11 Cepheid dataset. One of these models exhibits tension between the PL relation of the R11 cepheids and the MW+LMC cepheids, while the other does not. We extend our models to adequately account for tension between the cepheid data sets when appropriate. Our outlier treatment has a significant impact on the distance scales to Supernovae hosts with Cepheid distances, increasing the uncertainty in these distances by a median factor of ~30%. We further find that our Cepheid outlier treatment translates into a modest, but non-negligible increase in the statistical uncertainty of H0, addi...

  20. Detecting Anomalies in Unmanned Vehicles Using the Mahalanobis Distance

    E-Print Network [OSTI]

    Kaminka, Gal A.

    the vehicles deviations from nominal behavior. I. INTRODUCTION Unmanned Aerial Vehicles (UAVs) and UnmannedDetecting Anomalies in Unmanned Vehicles Using the Mahalanobis Distance Raz Lin, Eliyahu Khalastchi 52900 {linraz,galk}@cs.biu.ac.il Abstract-- The use of unmanned autonomous vehicles is becoming more

  1. Modelling long-distance seed dispersal in heterogeneous landscapes.

    SciTech Connect (OSTI)

    Levey, Douglas, J.; Tewlsbury, Joshua, J.; Bolker, Benjamin, M.

    2008-01-01

    1. Long-distance seed dispersal is difficult to measure, yet key to understanding plant population dynamics and community composition. 2. We used a spatially explicit model to predict the distribution of seeds dispersed long distances by birds into habitat patches of different shapes. All patches were the same type of habitat and size, but varied in shape. They occurred in eight experimental landscapes, each with five patches of four different shapes, 150 m apart in a matrix of mature forest. The model was parameterized with smallscale movement data collected from field observations of birds. In a previous study we validated the model by testing its predictions against observed patterns of seed dispersal in real landscapes with the same types and spatial configuration of patches as in the model. 3. Here we apply the model more broadly, examining how patch shape influences the probability of seed deposition by birds into patches, how dispersal kernels (distributions of dispersal distances) vary with patch shape and starting location, and how movement of seeds between patches is affected by patch shape. 4. The model predicts that patches with corridors or other narrow extensions receive higher numbers of seeds than patches without corridors or extensions. This pattern is explained by edgefollowing behaviour of birds. Dispersal distances are generally shorter in heterogeneous landscapes (containing patchy habitat) than in homogeneous landscapes, suggesting that patches divert the movement of seed dispersers, ‘holding’ them long enough to increase the probability of seed defecation in the patches. Dispersal kernels for seeds in homogeneous landscapes were smooth, whereas those in heterogenous landscapes were irregular. In both cases, long-distance (> 150 m) dispersal was surprisingly common, usually comprising approximately 50% of all dispersal events. 5. Synthesis . Landscape heterogeneity has a large influence on patterns of long-distance seed dispersal. Our results suggest that long-distance dispersal events can be predicted using spatially explicit modelling to scale-up local movements, placing them in a landscape context. Similar techniques are commonly used by landscape ecologists to model other types of movement; they offer much promise to the study of seed dispersal.

  2. Energy-beam-driven rapid fabrication system

    DOE Patents [OSTI]

    Keicher, David M. (Albuquerque, NM); Atwood, Clinton L. (Albuquerque, NM); Greene, Donald L. (Corrales, NM); Griffith, Michelle L. (Albuquerque, NM); Harwell, Lane D. (Albuquerque, NM); Jeantette, Francisco P. (Albuquerque, NM); Romero, Joseph A. (Albuquerque, NM); Schanwald, Lee P. (Albuquerque, NM); Schmale, David T. (Albuquerque, NM)

    2002-01-01

    An energy beam driven rapid fabrication system, in which an energy beam strikes a growth surface to form a molten puddle thereon. Feed powder is then injected into the molten puddle from a converging flow of feed powder. A portion of the feed powder becomes incorporated into the molten puddle, forcing some of the puddle contents to freeze on the growth surface, thereby adding an additional layer of material. By scanning the energy beam and the converging flow of feed powder across the growth surface, complex three-dimensional shapes can be formed, ready or nearly ready for use. Nearly any class of material can be fabricated using this system.

  3. Fiber optic mounted laser driven flyer plates

    SciTech Connect (OSTI)

    Paisley, Dennis L.

    1991-01-01

    A laser driven flyer plate where the flyer plate is deposited directly onto the squared end of an optical fiber. The plasma generated by a laser pulse drives the flyer plate toward a target. In another embodiment, a first metal layer is deposited onto the squared end of an optical fiber, followed by a layer of a dielectric material and a second metal layer. The laser pulse generates a plasma in the first metal layer, but the plasma is kept away from the second metal layer by the dielectric layer until the pressure reaches the point where shearing occurs.

  4. Fiber optic mounted laser driven flyer plates

    SciTech Connect (OSTI)

    Paisley, D.L.

    1990-12-31

    This invention is comprised of a laser driven flyer plate where the flyer plate is deposited directly onto the squared end of an optical fiber. The plasma generated by a laser pulse drives the flyer plate toward a target. In another embodiment, a first metal layer is deposited onto the squared end of an optical fiber, followed by a layer of a dielectric material and a second metal layer. The laser pulse generates a plasma in the first metal layer, but the plasma is kept away from the second metal layer by the dielectric layer until the pressure reaches the point where shearing occurs. 2 figs.

  5. Fiber optic mounted laser driven flyer plates

    SciTech Connect (OSTI)

    Paisley, D.L.

    1991-07-09

    A laser driven flyer plate is described where the flyer plate is deposited directly onto the squared end of an optical fiber. The plasma generated by a laser pulse drives the flyer plate toward a target. In another embodiment, a first metal layer is deposited onto the squared end of an optical fiber, followed by a layer of a dielectric material and a second metal layer. The laser pulse generates a plasma in the first metal layer, but the plasma is kept away from the second metal layer by the dielectric layer until the pressure reaches the point where shearing occurs.

  6. Fiber optic mounted laser driven flyer plates

    SciTech Connect (OSTI)

    Paisley, D.L.

    1990-01-01

    This invention is comprised of a laser driven flyer plate where the flyer plate is deposited directly onto the squared end of an optical fiber. The plasma generated by a laser pulse drives the flyer plate toward a target. In another embodiment, a first metal layer is deposited onto the squared end of an optical fiber, followed by a layer of a dielectric material and a second metal layer. The laser pulse generates a plasma in the first metal layer, but the plasma is kept away from the second metal layer by the dielectric layer until the pressure reaches the point where shearing occurs. 2 figs.

  7. Neutrino Physics with Accelerator Driven Subcritical Reactors

    E-Print Network [OSTI]

    Emilio Ciuffoli; Jarah Evslin; Fengyi Zhao

    2015-11-15

    Accelerator driven system (ADS) subcritical nuclear reactors are under development around the world. They will be intense sources of free, 30-50 MeV antimuon decay at rest antimuon neutrinos. These ADS reactor neutrinos can provide a robust test of the LSND anomaly and a precise measurement of the leptonic CP-violating phase delta, including sign(cos(delta)). The first phase of many ADS programs includes the construction of a low energy, high intensity proton or deuteron accelerator, which can yield competitive bounds on sterile neutrinos.

  8. Neutrino Physics with Accelerator Driven Subcritical Reactors

    E-Print Network [OSTI]

    Ciuffoli, Emilio; Zhao, Fengyi

    2015-01-01

    Accelerator driven system (ADS) subcritical nuclear reactors are under development around the world. They will be intense sources of free, 30-50 MeV antimuon decay at rest antimuon neutrinos. These ADS reactor neutrinos can provide a robust test of the LSND anomaly and a precise measurement of the leptonic CP-violating phase delta, including sign(cos(delta)). The first phase of many ADS programs includes the construction of a low energy, high intensity proton or deuteron accelerator, which can yield competitive bounds on sterile neutrinos.

  9. Heat pumping with optically driven excitons

    E-Print Network [OSTI]

    Erik M. Gauger; Joachim Wabnig

    2010-06-07

    We present a theoretical study showing that an optically driven excitonic two-level system in a solid state environment acts as a heat pump by means of repeated phonon emission or absorption events. We derive a master equation for the combined phonon bath and two-level system dynamics and analyze the direction and rate of energy transfer as a function of the externally accessible driving parameters. We discover that if the driving laser is detuned from the exciton transition, cooling the phonon environment becomes possible.

  10. Emergent hyperuniformity in periodically-driven emulsions

    E-Print Network [OSTI]

    Joost H. Weijs; Raphaël Jeanneret; Rémi Dreyfus; Denis Bartolo

    2015-04-28

    We report the emergence of large-scale hyperuniformity in microfluidic emulsions. Upon periodic driving confined emulsions undergo a first-order transition from a reversible to an irreversible dynamics. We evidence that this dynamical transition is accompanied by structural changes at all scales yielding macroscopic yet finite hyperuniform structures. Numerical simulations are performed to single out the very ingredients responsible for the suppression of density fluctuations. We show that as opposed to equilibrium systems the long-range nature of the hydrodynamic interactions are not required for the formation of hyperuniform patterns, thereby suggesting a robust relation between reversibility and hyperuniformity which should hold in a broad class of periodically driven materials.

  11. Advanced motor driven clamped borehole seismic receiver

    DOE Patents [OSTI]

    Engler, B.P.; Sleefe, G.E.; Striker, R.P.

    1993-02-23

    A borehole seismic tool is described including a borehole clamp which only moves perpendicular to the borehole. The clamp is driven by an electric motor, via a right angle drive. When used as a seismic receiver, the tool has a three part housing, two of which are hermetically sealed. Accelerometers or geophones are mounted in one hermetically sealed part, the electric motor in the other hermetically sealed part, and the clamp and right angle drive in the third part. Preferably the tool includes cable connectors at both ends. Optionally a shear plate can be added to the clamp to extend the range of the tool.

  12. Advanced motor driven clamped borehole seismic receiver

    DOE Patents [OSTI]

    Engler, Bruce P. (Sandoval County, NM); Sleefe, Gerard E. (Bernalillo County, NM); Striker, Richard P. (Bernalillo County, NM)

    1993-01-01

    A borehole seismic tool including a borehole clamp which only moves perpendicular to the borehole. The clamp is driven by an electric motor, via a right angle drive. When used as a seismic receiver, the tool has a three part housing, two of which are hermetically sealed. Accelerometers or geophones are mounted in one hermetically sealed part, the electric meter in the other hermetically sealed part, and the clamp and right angle drive in the third part. Preferably the tool includes cable connectors at both ends. Optionally a shear plate can be added to the clamp to extend the range of the tool.

  13. Electron self-injection in the proton-driven-plasma-wakefield acceleration

    SciTech Connect (OSTI)

    Hu, Zhang-Hu; Wang, You-Nian

    2013-12-15

    The self-injection process of plasma electrons in the proton-driven-plasma-wakefield acceleration scheme is investigated using a two-dimensional, electromagnetic particle-in-cell method. Plasma electrons are self-injected into the back of the first acceleration bucket during the initial bubble formation period, where the wake phase velocity is low enough to trap sufficient electrons. Most of the self-injected electrons are initially located within a distance of the skin depth c/?{sub pe} to the beam axis. A decrease (or increase) in the beam radius (or length) leads to a significant reduction in the total charges of self-injected electron bunch. Compared to the uniform plasma, the energy spread, emittance and total charges of the self-injected bunch are reduced in the plasma channel case, due to a reduced injection of plasma electrons that initially located further away from the beam axis.

  14. Accelerating Science Driven System Design With RAMP

    SciTech Connect (OSTI)

    Wawrzynek, John

    2015-05-01

    Researchers from UC Berkeley, in collaboration with the Lawrence Berkeley National Lab, are engaged in developing an Infrastructure for Synthesis with Integrated Simulation (ISIS). The ISIS Project was a cooperative effort for “application-driven hardware design” that engages application scientists in the early parts of the hardware design process for future generation supercomputing systems. This project served to foster development of computing systems that are better tuned to the application requirements of demanding scientific applications and result in more cost-effective and efficient HPC system designs. In order to overcome long conventional design-cycle times, we leveraged reconfigurable devices to aid in the design of high-efficiency systems, including conventional multi- and many-core systems. The resulting system emulation/prototyping environment, in conjunction with the appropriate intermediate abstractions, provided both a convenient user programming experience and retained flexibility, and thus efficiency, of a reconfigurable platform. We initially targeted the Berkeley RAMP system (Research Accelerator for Multiple Processors) as that hardware emulation environment to facilitate and ultimately accelerate the iterative process of science-driven system design. Our goal was to develop and demonstrate a design methodology for domain-optimized computer system architectures. The tangible outcome is a methodology and tools for rapid prototyping and design-space exploration, leading to highly optimized and efficient HPC systems.

  15. Outflow Driven Turbulence in Molecular Clouds

    E-Print Network [OSTI]

    Jonathan J. Carroll; Adam Frank; Eric G. Blackman; Andrew J. Cunningham; Alice C. Quillen

    2008-05-30

    In this paper we explore the relationship between protostellar outflows and turbulence in molecular clouds. Using 3-D numerical simulations we focus on the hydrodynamics of multiple outflows interacting within a parsec scale volume. We explore the extent to which transient outflows injecting directed energy and momentum into a sub-volume of a molecular cloud can be converted into random turbulent motions. We show that turbulence can readily be sustained by these interactions and show that it is possible to broadly characterize an effective driving scale of the outflows. We compare the velocity spectrum obtained in our studies to that of isotropically forced hydrodynamic turbulence finding that in outflow driven turbulence a power law is indeed achieved. However we find a steeper spectrum (beta ~ 3) is obtained in outflow driven turbulence models than in isotropically forced simulations (beta ~ 2). We discuss possible physical mechanisms responsible for these results as well and their implications for turbulence in molecular clouds where outflows will act in concert with other processes such as gravitational collapse.

  16. United States Industrial Motor-Driven Systems Market Assessment...

    Broader source: Energy.gov (indexed) [DOE]

    sectors. United States Industrial Motor-Driven Systems Market Assessment: Charting a Roadmap to Energy Savings for Industry (June 1998) More Documents & Publications U.S....

  17. Save Energy Now in Your Motor-Driven Systems

    SciTech Connect (OSTI)

    2006-01-01

    This DOE Industrial Technologies Program fact sheet describes how manufacturing plants can save energy and money by making energy efficiency improvements to their industrial motor-driven systems.

  18. Betatron Radiation from a Beam Driven Plasma Source Litos, M...

    Office of Scientific and Technical Information (OSTI)

    Betatron Radiation from a Beam Driven Plasma Source Litos, M.; Corde, S.; SLAC 43 PARTICLE ACCELERATORS; ACCELERATION; ACCELERATORS; BETATRON OSCILLATIONS; BETATRONS;...

  19. CESC-Webinar: Building an Innovation and Entrepreneurship Driven...

    Open Energy Info (EERE)

    Driven Economy: How Policies Can Foster Risk Capital Investment in Renewable Energy Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Building an Innovation and...

  20. Solar-Driven Microbial Photoelectrochemical System for Energy Conversion

    E-Print Network [OSTI]

    Wang, Hanyu

    2015-01-01

    A Perspective on Solar-Driven Water Splitting with All-OxideMicrobial Electrolysis Cells. Water Res. 2008, 42, 4172-Hydrogen Generation from Water Using Solar Energy. Materials

  1. Solar-Driven Microbial Photoelectrochemical System for Energy Conversion

    E-Print Network [OSTI]

    Wang, Hanyu

    2015-01-01

    Visible Light Driven Photocatalysis. Chem. Commun. 2011, 47,R. , Visible-Light Photocatalysis in Nitrogen-Doped TitaniumSolar Absorption for Photocatalysis with Black Hydrogenated

  2. An Accurate Distance to High-Velocity Cloud Complex C

    E-Print Network [OSTI]

    C. Thom; J. E. G. Peek; M. E. Putman; Carl Heiles; K. M. G. Peek; R. Wilhelm

    2008-04-23

    We report an accurate distance of d = 10+/-2.5kpc to the high-velocity cloud Complex C. Using high signal-to-noise Keck/HIRES spectra of two horizontal-branch stars, we have detected CaII K absorption lines from the cloud. Significant non-detections toward a further 3 stars yield robust lower distance limits. The resulting HI mass of Complex C is 4.9^{+2.8}_{-2.2} x 10^6 Msun; a total mass of 8.2^{+4.6}_{-2.6} x 10^6 Msun is implied, after corrections for helium and ionization. At 10kpc, Complex C has physical dimensions 3x15 kpc, and if it is as thick as it is wide, then the average density is log ~ -2.5. We estimate the contribution of Complex C to the mass influx may be as high as ~0.14 Msun/yr.

  3. A New Resource for College Distance Education Astronomy Laboratory Exercises

    E-Print Network [OSTI]

    Vogt, Nicole P; Muise, Amy Smith

    2015-01-01

    This article introduces a set of distance education astronomy laboratory exercises for use by college students and instructors and discuss first usage results. This General Astronomy Education Source (GEAS) exercise set contains eight two-week projects designed to guide students through both core content and mathematical applications of general astronomy material. Projects are divided between hands-on activities and computer-aided analyses of modern astronomical data. The suite of online resources includes student and instructor guides, laboratory report templates, learning objectives, video tutorials, plotting tools, and web-based applications that allow students to analyze both images and spectra of astronomical objects. A pilot usage study indicates that distance learners using these materials perform as well or better than a comparison cohort of on-campus students. We are actively seeking collaborators to use these resources in astronomy courses and other educational venues.

  4. Distance Priors from \\emph{Planck} 2015 data

    E-Print Network [OSTI]

    Qing-Guo Huang; Ke Wang; Sai Wang

    2015-09-03

    We update the distance priors by adopting $Planck~ \\textrm{TT,TE,EE}+\\textrm{lowP}$ data released in 2015, and our results impose at least $30\\%$ tighter constraints than those from $Planck~ \\textrm{TT}+\\textrm{lowP}$. Combining the distance priors with the combination of supernova Union~2.1 compilation of 580 SNe (Union~2.1) and low redshift Baryon Acoustic Oscillation (BAO) data, we constrain the cosmological parameters in the freely binned dark energy (FBDE) and FBDE$+\\Omega_k$ models respectively, and find that the equations of state of dark energy in both models are consistent with $w=-1$. Furthermore, we show that the tension with the BAO data at $z=2.34$ from Ly$\\alpha$ forest (Ly$\\alpha$F) auto-correlation and Combined Ly$\\alpha$F cannot be relaxed in the FBDE and FBDE$+\\Omega_k$ models.

  5. Gromov-Hausdorff Distance for Quantum Metric Spaces

    E-Print Network [OSTI]

    Marc A. Rieffel

    2003-02-20

    By a quantum metric space we mean a C^*-algebra (or more generally an order-unit space) equipped with a generalization of the Lipschitz seminorm on functions which is defined by an ordinary metric. We develop for compact quantum metric spaces a version of Gromov-Hausdorff distance. We show that the basic theorems of the classical theory have natural quantum analogues. Our main example involves the quantum tori, $A_{\\th}$. We show, for consistently defined ``metrics'', that if a sequence $\\{\\th_n\\}$ of parameters converges to a parameter $\\th$, then the sequence $\\{A_{\\th_n}\\}$ of quantum tori converges in quantum Gromov-Hausdorff distance to $A_{\\th}$.

  6. A characterization of Q-polynomial distance-regular graphs

    E-Print Network [OSTI]

    Jurisic, Aleksandar; Zitnik, Arjana

    2009-01-01

    We obtain the following characterization of $Q$-polynomial distance-regular graphs. Let $\\G$ denote a distance-regular graph with diameter $d\\ge 3$. Let $E$ denote a minimal idempotent of $\\G$ which is not the trivial idempotent $E_0$. Let $\\{\\theta_i^*\\}_{i=0}^d$ denote the dual eigenvalue sequence for $E$. We show that $E$ is $Q$-polynomial if and only if (i) the entry-wise product $E \\circ E$ is a linear combination of $E_0$, $E$, and at most one other minimal idempotent of $\\G$; (ii) there exists a complex scalar $\\beta$ such that $\\theta^*_{i-1}-\\beta \\theta^*_i + \\theta^*_{i+1}$ is independent of $i$ for $1 \\le i \\le d-1$; (iii) $\\theta^*_i \

  7. Scanning optical microscope with long working distance objective

    DOE Patents [OSTI]

    Cloutier, Sylvain G. (Newark, DE)

    2010-10-19

    A scanning optical microscope, including: a light source to generate a beam of probe light; collimation optics to substantially collimate the probe beam; a probe-result beamsplitter; a long working-distance, infinity-corrected objective; scanning means to scan a beam spot of the focused probe beam on or within a sample; relay optics; and a detector. The collimation optics are disposed in the probe beam. The probe-result beamsplitter is arranged in the optical paths of the probe beam and the resultant light from the sample. The beamsplitter reflects the probe beam into the objective and transmits resultant light. The long working-distance, infinity-corrected objective is also arranged in the optical paths of the probe beam and the resultant light. It focuses the reflected probe beam onto the sample, and collects and substantially collimates the resultant light. The relay optics are arranged to relay the transmitted resultant light from the beamsplitter to the detector.

  8. Light deflection in Weyl gravity: critical distances for photon paths

    E-Print Network [OSTI]

    S. Pireaux

    2004-03-16

    The Weyl gravity appears to be a very peculiar theory. The contribution of the Weyl linear parameter to the effective geodesic potential is opposite for massive and nonmassive geodesics. However, photon geodesics do not depend on the unknown conformal factor, unlike massive geodesics. Hence light deflection offers an interesting test of the Weyl theory. In order to investigate light deflection in the setting of Weyl gravity, we first distinguish between a weak field and a strong field approximation. Indeed, the Weyl gravity does not turn off asymptotically and becomes even stronger at larger distances. We then take full advantage of the conformal invariance of the photon effective potential to provide the key radial distances in Weyl gravity. According to those, we analyze the weak and strong field regime for light deflection. We further show some amazing features of the Weyl theory in the strong regime.

  9. Electrical probe diagnostics for the laminar flame quenching distance

    SciTech Connect (OSTI)

    Karrer, Maxime; Makarov, Maxime; Bellenoue, Marc; Labuda, Sergei; Sotton, Julien

    2010-02-15

    A simplified theory, previously developed for the general case of weakly ionized gas flow, is used to predict electrical probe response when the flame is quenched on the probe surface. This theory is based on the planar model of space charge sheaths around the measuring electrode. For the flame quenching case, by assuming that the sheath thickness is comparable with the thermal boundary layer thickness, probe current can be related to flame quenching distance. The theoretical assumptions made to obtain the analytical formulation of probe current were experimentally proved by using direct visualization and high-frequency PIV. The direct visualization method was also used to validate the results of flame quenching distance values obtained with electrical probe. The electrical probe diagnostics have been verified for both head-on and sidewall flame quenching regimes and for stoichiometric methane/air and propane/air mixtures in a pressure range of 0.05-0.6 MPa. (author)

  10. THE MEMBERSHIP AND DISTANCE OF THE OPEN CLUSTER COLLINDER 419

    SciTech Connect (OSTI)

    Roberts, Lewis C.; Gies, Douglas R.; Parks, J. Robert; Grundstrom, Erika D.; McSwain, M. Virginia; Berger, David H.; Mason, Brian D.; Ten Brummelaar, Theo A.; Turner, Nils H. E-mail: gies@chara.gsu.ed E-mail: erika.grundstrom@vanderbilt.ed E-mail: dberger@sysplan.co E-mail: theo@chara-array.or

    2010-09-15

    The young open cluster Collinder 419 surrounds the massive O star, HD 193322, that is itself a remarkable multiple star system containing at least four components. Here we present a discussion of the cluster distance based upon new spectral classifications of the brighter members, UBV photometry, and an analysis of astrometric and photometric data from the third U. S. Naval Observatory CCD Astrograph Catalog and Two Micron All Sky Survey Catalog. We determine an average cluster reddening of E(B - V) = 0.37 {+-} 0.05 mag and a cluster distance of 741 {+-} 36 pc. The cluster probably contains some very young stars that may include a reddened M3 III star, IRAS 20161+4035.

  11. Distance-redshift relations in an anisotropic cosmological model

    SciTech Connect (OSTI)

    Menezes, R. S. Jr. [Instituto Federal da Bahia, Salvador, BA (Brazil); Pigozzo, C.; Carneiro, S., E-mail: rsmjr@ifba.edu.br, E-mail: cpigozzo@ufba.br, E-mail: saulo.carneiro.ufba@gmail.com [Instituto de Física, Universidade Federal da Bahia, Salvador, Bahia (Brazil)

    2013-03-01

    In this paper we study an anisotropic model generated from a particular Bianchi type-III metric, which is a generalization of Gödel's metric and an exact solution of Einstein's field equations. We analyse type Ia supernova data, namely the SDSS sample calibrated with the MLCS2k2 fitter, and we verify in which ranges of distances and redshifts the anisotropy could be observed. We also consider, in a joint analysis, the position of the first peak in the CMB anisotropy spectrum, as well as current observational constraints on the Hubble constant. We conclude that a small anisotropy is permitted by the data, and that more accurate measurements of supernova distances above z = 2 might indicate the existence of such anisotropy in the universe.

  12. Short distance signatures in Cosmology: Why not in Black Holes?

    E-Print Network [OSTI]

    Roberto Casadio; Laura Mersini

    2002-08-07

    Current theoretical investigations seem to indicate the possibility of observing signatures of short distance physics in the Cosmic Microwave Background spectrum. We try to gain a deeper understanding on why all information about this regime is lost in the case of Black Hole radiation but not necessarily so in a cosmological setting by using the moving mirror as a toy model for both backgrounds. The different responses of the Hawking and Cosmic Microwave Background spectra to short distance physics are derived in the appropriate limit when the moving mirror mimics a Black Hole background or an expanding universe. The different sensitivities to new physics, displayed by both backgrounds, are clarified through an averaging prescription that accounts for the intrinsic uncertainty in their quantum fluctuations. We then proceed to interpret the physical significance of our findings for time-dependent backgrounds in the light of nonlocal string theory.

  13. Evaluating a Master's Degree Program via Distance Education 

    E-Print Network [OSTI]

    Lara-Alecio, Rafael; Kemp, Janie; Treviñ o, Polly; Tong, Fuhui; Castillo, Raymond

    2010-10-22

    -1 Evaluating a Master?s Degree Program via Distance Education Dr. Rafael Lara-Alecio Janie Kemp Polly Trevi?o Fuhui Tong Raymond Castillo TTVN Conference Galveston, TX January 18, 2006 Texas A&M University Bilingual Education Program Dept... and High School Levels Online Program Texas A&M University Bilingual Education Programs ? Undergraduate Program ? Currently 105 undergraduate students working toward teaching degree and certification in Bil/ESL ? Master?s Program ? First Master?s...

  14. Time, Distance, Velocity, Redshift: a personal guided tour

    E-Print Network [OSTI]

    T. Kiang

    2003-08-01

    An attempt to answer the question 'Can we observe galaxies that recede faster than light ?' led to a re-examination of the notions of time, distance, velocity and redshift as they occur in newtonian physics, special relativity, general relativity and cosmology. A number of misconceptions were uncovered. It was found that, once freed of special relativity preconceptions, the above question is easily and unequivocally answered

  15. Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

    E-Print Network [OSTI]

    Le, Minh T. N.

    MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis elegans microRNA lin-4, has been implicated in the regulation of neural and hematopoietic ...

  16. {00012119.DOC /} Graduate Medical Education 540 E. Canfield Detroit, MI 48201 Phone 313-577-5189 Fax 313-577-5245

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    {00012119.DOC /} Graduate Medical Education 540 E. Canfield · Detroit, MI 48201 · Phone 313; This agreement of appointment by and between WSU, whose address is 540 East Canfield, Detroit, Michigan 48201

  17. ANRV253-MI59-05 ARI 21 April 2005 18:7 Diversity and Evolution of

    E-Print Network [OSTI]

    Plotkin, Joshua B.

    ANRV253-MI59-05 ARI 21 April 2005 18:7 R E V I E W S IN A D V A N CE Diversity and Evolution: pohlschr@sas.upenn.edu, njhand@sas.upenn.edu, kdilks@sas.upenn.edu, alexh@sas.upenn.edu 2 University of L. Rev. Microbiol. 2005. 59:91­111 doi: 10.1146/ annurev.micro.59.030804.121353 Copyright c 2005

  18. AN IMPROVED METHOD TO TEST THE DISTANCE-DUALITY RELATION

    SciTech Connect (OSTI)

    Yang, Xi; Yu, Hao-Ran; Zhang, Tong-Jie [Department of Astronomy, Beijing Normal University, Beijing 100875 (China)] [Department of Astronomy, Beijing Normal University, Beijing 100875 (China); Zhang, Zhi-Song, E-mail: tjzhang@bnu.edu.cn [Department of Aerospace Engineering, School of Astronautics, Harbin Institute of Technology (HIT), Harbin Heilongjiang 150001 (China)] [Department of Aerospace Engineering, School of Astronautics, Harbin Institute of Technology (HIT), Harbin Heilongjiang 150001 (China)

    2013-11-10

    Many researchers have performed cosmological-model-independent tests for the distance-duality (DD) relation. Theoretical work has been conducted based on the results of these tests. However, we find that almost all of these tests were perhaps not cosmological-model-independent after all, because the distance moduli taken from a given type Ia supernovae (SNe Ia) compilation are dependent on a given cosmological model and Hubble constant. In this Letter, we overcome these defects and by creating a new cosmological-model-independent test for the DD relation. We use the original data from the Union2 SNe Ia compilation and the angular diameter distances from two galaxy cluster samples compiled by De Filippis et al. and Bonamente et al. to test the DD relation. Our results suggest that the DD relation is compatible with observations, and the spherical model is slightly better than the elliptical model at describing the intrinsic shape of galaxy clusters if the DD relation is valid. However, these results are different from those of previous work.

  19. A short working distance multiple crystal x-ray spectrometer

    SciTech Connect (OSTI)

    Dickinson, B.; Seidler, G. T.; Webb, Z. W.; Bradley, J. A.; Nagle, K. P. [Department of Physics, University of Washington, Seattle, Washington 98195 (United States); Heald, S. M. [Advanced Photon Source, Argonne National Laboratories, Argonne, Illinois 60439 (United States); Gordon, R. A. [Department of Physics, Simon Fraser University, Burnaby, British Columbia V5A 1S6 (Canada); Chou, I. M. [U.S. Geological Survey, Reston, Virginia 20192 (United States)

    2008-12-15

    For x-ray spot sizes of a few tens of microns or smaller, a millimeter-sized flat analyzer crystal placed {approx}1 cm from the sample will exhibit high energy resolution while subtending a collection solid angle comparable to that of a typical spherically bent crystal analyzer (SBCA) at much larger working distances. Based on this observation and a nonfocusing geometry for the analyzer optic, we have constructed and tested a short working distance (SWD) multicrystal x-ray spectrometer. This prototype instrument has a maximum effective collection solid angle of 0.14 sr, comparable to that of 17 SBCA at 1 m working distance. We find good agreement with prior work for measurements of the Mn K{beta} x-ray emission and resonant inelastic x-ray scattering for MnO, and also for measurements of the x-ray absorption near-edge structure for Dy metal using L{alpha}{sub 2} partial-fluorescence yield detection. We discuss future applications at third- and fourth-generation light sources. For concentrated samples, the extremely large collection angle of SWD spectrometers will permit collection of high-resolution x-ray emission spectra with a single pulse of the Linac Coherent Light Source. The range of applications of SWD spectrometers and traditional multi-SBCA instruments has some overlap, but also is significantly complementary.

  20. Laser-Driven Mini-Thrusters

    SciTech Connect (OSTI)

    Sterling, Enrique; Lin Jun; Sinko, John; Kodgis, Lisa; Porter, Simon; Pakhomov, Andrew V. [Department of Physics, University of Alabama in Huntsville, Huntsville, AL 35899 (United States); Larson, C. William; Mead, Franklin B. Jr. [Propulsion Directorate, Air Force Research Laboratory, Edwards AFB, CA 93524-7680 (United States)

    2006-05-02

    Laser-driven mini-thrusters were studied using Delrin registered and PVC (Delrin registered is a registered trademark of DuPont) as propellants. TEA CO2 laser ({lambda} = 10.6 {mu}m) was used as a driving laser. Coupling coefficients were deduced from two independent techniques: force-time curves measured with a piezoelectric sensor and ballistic pendulum. Time-resolved ICCD images of the expanding plasma and combustion products were analyzed in order to determine the main process that generates the thrust. The measurements were also performed in a nitrogen atmosphere in order to test the combustion effects on thrust. A pinhole transmission experiment was performed for the study of the cut-off time when the ablation/air breakdown plasma becomes opaque to the incoming laser pulse.

  1. Accelerator Driven Nuclear Energy: The Thorium Option

    ScienceCinema (OSTI)

    Raja, Rajendran

    2010-01-08

    Conventional nuclear reactors use enriched Uranium as fuel and produce nuclear waste which needs to be stored away for over 10,000 years.   At the current rate of use, existing sources of Uranium will last for 50-100 years.  We describe a solution to the problem that uses particle accelerators to produce fast neutrons that can be used to burn existing nuclear waste and produce energy.  Such systems, initially proposed by Carlo Rubbia and collaborators in the 1990's, are being seriously considered by many countries as a possible solution to the green energy problem.  Accelerator driven reactors operate in a sub-critical regime and, thus, are safer and can obtain energy from plentiful elements such as Thorium-232 and Uranium-238. What is missing is the high intensity (10MW) accelerator that produces 1 GeV protons. We will describe scenarios which if implemented will make such systems a reality.  

  2. Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562

    SciTech Connect (OSTI)

    Liu, Li, E-mail: liuli029@yahoo.cn [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China); Wang, Sitao; Chen, Renan; Wu, Yanlan; Zhang, Bei; Huang, Siyong; Zhang, Jingyi; Xiao, Fang; Wang, Meng; Liang, Yingmin [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)] [Department of Hematology, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038 (China)

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer Increased c-myc expression in imatinib resistant CML cells. Black-Right-Pointing-Pointer c-myc contributes the imatinib resistance in CML cells. Black-Right-Pointing-Pointer c-myc transcriptionally reduces the expression of miR-144/451 in K562R cells. Black-Right-Pointing-Pointer Restoration of miR-144/451 reverses the resistance of K562R cells to imatinib. -- Abstract: Imatinib resistance remains the big hurdle for CML therapy. Previous study reveals that c-myc is important for bcr-abl CML cell proliferation, while its role in imatinib resistance is largely unknown. In this study, we first found that c-myc expression is upregulated in imatinib resistant K562R cells, which in turn enhances the expression of miR-144/451. Knockdown of c-myc or restoration of miR-144/451 in the K562R cells sensitizes K562R cells to imatinib therapy. Our study here reveals an regulatory pathway between myc and miR-144/451 and highlights that targeting either myc or miR-144/451 might be valuable for eliminating the imatinib resistant CML cells.

  3. Application of a Laser-Wakefield Driven Monochromatic Photon Source to

    E-Print Network [OSTI]

    Umstadter, Donald

    of approximately 170. I. INTRODUCTION HE Diocles laser facility at The University of Nebraska- Lincoln (UNL is with the Department of Nuclear Engineering and Radiological Sciences of the University of Michigan, Ann Arbor, MI and Radiological Sciences of the University of Michigan, Ann Arbor, MI 48109 USA (tel: 734-615-7830, e

  4. Frameworks for Business-driven Service Level Management

    E-Print Network [OSTI]

    Frameworks for Business-driven Service Level Management A Criteria-based Comparison of ITIL-driven IT Management: the IT Infrastructure Library (ITIL) with its SLM reference process and the NGOSS SLA Management a realistic IT scenario. These criteria are applied to ITIL and NGOSS in order to elaborate possible areas

  5. Global Mode Analysis of Centrifugal and Curvature Driven

    E-Print Network [OSTI]

    Columbia University

    Global Mode Analysis of Centrifugal and Curvature Driven Interchange Instabilities Benjamin Joseph Reserved #12;ABSTRACT Global Mode Analysis of Centrifugal and Curvature Driven Interchange Modes Benjamin- sure and centrifugal forces created in a laboratory magnetic dipole is presented. The mode structures

  6. Proof-of-Principle Detonation Driven, Linear Electric Generator Facility

    E-Print Network [OSTI]

    Texas at Arlington, University of

    Proof-of-Principle Detonation Driven, Linear Electric Generator Facility Eric M. Braun, Frank K. Lu a generator and produce electricity.4­6 Since the majority of power in the world is generated by deflagrative is described in which a detonation-driven piston system has been integrated with a linear generator in order

  7. Osmotically driven flows in microchannels separated by a semipermeable membrane

    E-Print Network [OSTI]

    Osmotically driven flows in microchannels separated by a semipermeable membrane Kare Hartvig Jensen-on-a-chip systems with microchannels separated by integrated membranes allowing for osmotically driven microflows between the experimental results and the predictions of the model. Our motivation for studying osmotically

  8. Dynamics of Passive Scalars and Probe Particles in Driven

    E-Print Network [OSTI]

    Dynamics of Passive Scalars and Probe Particles in Driven Diffusive Systems Sakuntala Chatterjee my parents #12;Contents Synopsis i 1 Introduction 1 1.1 Passive Scalar Advection . . . . . . . . . . . . . . . . . . . . . . . 5 1.2 Probe Particles in a Driven Diffusive Medium . . . . . . . . . . . 9 2 Dynamics of Passive

  9. Design-Driven Compilation Radu Rugina and Martin Rinard

    E-Print Network [OSTI]

    Rinard, Martin

    Design-Driven Compilation Radu Rugina and Martin Rinard Laboratory for Computer Science introduces design-driven compilation, an approach in which the compiler uses design information to drive its, and support for local analysis, separate compilation, and libraries. It can also simplify the compiler

  10. DesignDriven Compilation \\Lambda Radu Rugina and Martin Rinard

    E-Print Network [OSTI]

    Rugina, Radu

    Design­Driven Compilation \\Lambda Radu Rugina and Martin Rinard Laboratory for Computer Science introduces design­driven compilation, an approach in which the compiler uses design information to drive its; analysis modularity, with support for lo­ cal analysis, separate compilation, and library support

  11. DesignDriven Compilation Radu Rugina and Martin Rinard

    E-Print Network [OSTI]

    Rinard, Martin

    Design­Driven Compilation Radu Rugina and Martin Rinard Laboratory for Computer Science introduces design­driven compilation, an approach in which the compiler uses design information to drive its, and support for local analysis, separate compilation, and libraries. It can also simplify the compiler

  12. Design-Driven Compilation Radu Rugina and Martin Rinard

    E-Print Network [OSTI]

    Rinard, Martin

    Design-Driven Compilation Radu Rugina and Martin Rinard Laboratory for Computer Science introduces design-driven compilation, an approach in which the compiler uses design information to drive its; analysis modularity, with support for lo- cal analysis, separate compilation, and library support

  13. Pellet Driven Disruptions in Tokamaks H.R. Strauss

    E-Print Network [OSTI]

    Strauss, Hank

    Pellet Driven Disruptions in Tokamaks H.R. Strauss Courant Institute of Mathematical Sciences New York University W. Park Princeton Plasma Physics Laboratory Abstract Pellet injection can trigger ballooning like instability in tokamaks, driven by the large pressure perturbation of the pellet cloud

  14. High speed, long distance, data transmission multiplexing circuit

    DOE Patents [OSTI]

    Mariotti, Razvan (Boulder, CO)

    1991-01-01

    A high speed serial data transmission multiplexing circuit, which is operable to accurately transmit data over long distances (up to 3 Km), and to multiplex, select and continuously display real time analog signals in a bandwidth from DC to 100 Khz. The circuit is made fault tolerant by use of a programmable flywheel algorithm, which enables the circuit to tolerate one transmission error before losing synchronization of the transmitted frames of data. A method of encoding and framing captured and transmitted data is used which has a low overhead and prevents some particular transmitted data patterns from locking an included detector/decoder circuit.

  15. Large Distance Continuous Variables Communication with Concatenated Swaps

    E-Print Network [OSTI]

    Muhammad Asjad; Stefano Zippilli; Paolo Tombesi; David Vitali

    2015-04-01

    The radiation-pressure interaction between electromagnetic fields and mechanical resonators can be used to efficiently entangle two light fields which couple to a single mechanical mode. We analyze the performance of this process under realistic optomechanical conditions, and we determine the effectiveness of the resulting entanglement as a resource for quantum teleportation of continuous-variable light signals, over large distances, mediated by concatenated swap operations. We study the sensitiveness of the protocol to the quality factor of the mechanical systems, and its performance in non-ideal situations in which losses and reduced detection efficiencies are taken into account.

  16. Gamma ray burst distances and the timescape cosmology

    E-Print Network [OSTI]

    Peter R. Smale

    2011-08-22

    Gamma ray bursts can potentially be used as distance indicators, providing the possibility of extending the Hubble diagram to redshifts ~7. Here we follow the analysis of Schaefer (2007), with the aim of distinguishing the timescape cosmological model from the \\LambdaCDM model by means of the additional leverage provided by GRBs in the range 2 < z < 7. We find that the timescape model fits the GRB sample slightly better than the \\LambdaCDM model, but that the systematic uncertainties are still too little understood to distinguish the models.

  17. The effect of weak lensing on distance estimates from supernovae

    SciTech Connect (OSTI)

    Smith, Mathew; Maartens, Roy [Department of Physics, University of the Western Cape, Cape Town 7535 (South Africa); Bacon, David J.; Nichol, Robert C.; Campbell, Heather; D'Andrea, Chris B. [Institute of Cosmology and Gravitation, University of Portsmouth, Portsmouth, PO1 3FX (United Kingdom); Clarkson, Chris [Astrophysics, Cosmology and Gravity Centre (ACGC), Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701 (South Africa); Bassett, Bruce A. [South African Astronomical Observatory, P.O. Box 9, Observatory 7935 (South Africa); Cinabro, David [Wayne State University, Department of Physics and Astronomy, Detroit, MI 48202 (United States); Finley, David A.; Frieman, Joshua A. [Center for Particle Astrophysics, Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510 (United States); Galbany, Lluis [CENTRA Centro Multidisciplinar de Astrofísica, Instituto Superior Técnico, Av. Rovisco Pais 1, 1049-001 Lisbon (Portugal); Garnavich, Peter M. [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Olmstead, Matthew D. [Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112 (United States); Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Shapiro, Charles [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, La Canada Flintridge, CA 91109 (United States); Sollerman, Jesper, E-mail: matsmith2@gmail.com [The Oskar Klein Centre, Department of Astronomy, AlbaNova, SE-106 91 Stockholm (Sweden)

    2014-01-01

    Using a sample of 608 Type Ia supernovae from the SDSS-II and BOSS surveys, combined with a sample of foreground galaxies from SDSS-II, we estimate the weak lensing convergence for each supernova line of sight. We find that the correlation between this measurement and the Hubble residuals is consistent with the prediction from lensing (at a significance of 1.7?). Strong correlations are also found between the residuals and supernova nuisance parameters after a linear correction is applied. When these other correlations are taken into account, the lensing signal is detected at 1.4?. We show, for the first time, that distance estimates from supernovae can be improved when lensing is incorporated, by including a new parameter in the SALT2 methodology for determining distance moduli. The recovered value of the new parameter is consistent with the lensing prediction. Using cosmic microwave background data from WMAP7, H {sub 0} data from Hubble Space Telescope and Sloan Digital Sky Survey (SDSS) Baryon acoustic oscillations measurements, we find the best-fit value of the new lensing parameter and show that the central values and uncertainties on ? {sub m} and w are unaffected. The lensing of supernovae, while only seen at marginal significance in this low-redshift sample, will be of vital importance for the next generation of surveys, such as DES and LSST, which will be systematics-dominated.

  18. V838 Mon: light echo evolution and distance estimate

    E-Print Network [OSTI]

    Lisa A. Crause; Warrick A. Lawson; John W. Menzies; Fred Marang

    2005-01-22

    Following its 2002 February eruption, V838 Mon developed a light echo that continues to expand and evolve as light from the outburst scatters off progressively more distant circumstellar and/or interstellar material. Multi-filter images of the light echo, obtained with the South African Astronomical Observatory (SAAO) 1.0-m telescope between 2002 May and 2004 December, are analysed and made available electronically. The expansion of the light echo is measured from the images and the data compared with models for scattering by a thin sheet and a thin shell of dust. From these model results we infer that the dust is likely in the form of a thin sheet distant from the star, suggesting that the material is of interstellar origin, rather than being from earlier stages in the star's evolution. Although the fit is uncertain, we derive a stellar distance of ~ 9 kpc and a star-dust distance of ~ 5 pc, in good agreement with recent results reported from other methods. We also present JHKL and Cousins UBVRI photometry obtained at the SAAO during the star's second, third and fourth observing seasons post-outburst. These data show complex infrared colour behaviour while V838 Mon is slowly brightening in the optical.

  19. Nonlinear, noniterative, single-distance phase retrieval and developmental biology

    SciTech Connect (OSTI)

    Moosmann, Julian; Altapova, Venera; Haenschke, Daniel; Hofmann, Ralf; Baumbach, Tilo

    2012-05-17

    For coherent X-ray imaging, based on phase contrast through free-space Fresnel propagation, we discuss two noniterative, nonlinear approaches to the phase-retrieval problem from a single-distance intensity map of a pure-phase object. On one hand, a perturbative set-up is proposed where nonlinear corrections to the linearized transport-of-intensity situation are expanded in powers of the object-detector distance z and are evaluated in terms of the linear estimate. On the other hand, a nonperturbative projection algorithm, which is based on the (linear and local) contrast-transfer function (CTF), works with an effective phase in Fourier space. This effective phase obeys a modified CTF relation between intensity contrast at z > 0 and phase contrast at z= 0: Unphysical singularities of the local CTF model are cut off to yield 'quasiparticles' in analogy to the theory of the Fermi liquid. By identifying the positions of the zeros of the Fourier transformed intensity contrast as order parameters for the dynamical breaking of scaling symmetry we investigate the phase structure of the forward-propagation problem when interpreted as a statistical system. Results justify the quasiparticle approach for a wide range of intermediary phase variations. The latter algorithm is applied to data from biological samples recorded at the beamlines TopoTomo and ID19 at ANKA and ESRF, respectively.

  20. Impact of receptor-ligand distance on adhesion cluster stability

    E-Print Network [OSTI]

    T. Erdmann; U. S. Schwarz

    2007-07-16

    Cells in multicellular organisms adhere to the extracellular matrix through two-dimensional clusters spanning a size range from very few to thousands of adhesion bonds. For many common receptor-ligand systems, the ligands are tethered to a surface via polymeric spacers with finite binding range, thus adhesion cluster stability crucially depends on receptor-ligand distance. We introduce a one-step master equation which incorporates the effect of cooperative binding through a finite number of polymeric ligand tethers. We also derive Fokker-Planck and mean field equations as continuum limits of the master equation. Polymers are modeled either as harmonic springs or as worm-like chains. In both cases, we find bistability between bound and unbound states for intermediate values of receptor-ligand distance and calculate the corresponding switching times. For small cluster sizes, stochastic effects destabilize the clusters at large separation, as shown by a detailed analysis of the stochastic potential resulting from the Fokker-Planck equation.

  1. Support for Cost Analyses on Solar-Driven High Temperature Thermochemi...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Support for Cost Analyses on Solar-Driven High Temperature Thermochemical Water-Splitting Cycles Support for Cost Analyses on Solar-Driven High Temperature Thermochemical...

  2. Temperature-driven phase transformation in Y3Co: Neutron scattering...

    Office of Scientific and Technical Information (OSTI)

    Temperature-driven phase transformation in Y3Co: Neutron scattering and first-principles studies Citation Details In-Document Search Title: Temperature-driven phase transformation...

  3. Choosing good distance metrics and local planners for probabilistic roadmap motion planning methods 

    E-Print Network [OSTI]

    Bayazit, Osman Burchan

    1998-01-01

    This thesis presents a comparative evaluation of different distance metrics and local planners within the context of probabilistic roadmap methods for motion planning. Both C-space and Workspace distance metrics and local planners are considered...

  4. The Perception and Cognition of Environmental Distance: Direct Sources of Information"

    E-Print Network [OSTI]

    Montello, Daniel R.

    efficiently (time, money, food). Clearly, knowledge of distances in the environment "affects the decision reflect the human desire to minimize functional distance (Deutsch and Isard 1961; Golledge and Stimson

  5. Hybrid intensity and time-of-flight signal processing techniques for intelligent distance sensors

    E-Print Network [OSTI]

    Hiromi, Itariu

    2013-01-01

    With the advent of "smart" consumer electronics, distance sensing is an increasingly important field in optical sensing. A novel approach to active infrared(IR) 1D distance sensing is proposed, employing both intensity and ...

  6. Yet Another Secure Distance-Bounding Protocol Ventzislav Nikov and Marc Vauclair

    E-Print Network [OSTI]

    International Association for Cryptologic Research (IACR)

    Yet Another Secure Distance-Bounding Protocol Ventzislav Nikov and Marc Vauclair NXP Semiconductors, Leuven, Belgium, ventzislav.nikov@nxp.com, marc.vauclair@nxp.com Abstract. Distance-bounding protocols

  7. A systematic determination of legends for destination and distance signs in Texas 

    E-Print Network [OSTI]

    McClure, Wesley Glen

    1998-01-01

    Destination and Distance signs are guide signs which are commonly used along rural highways in Texas to display the names of the destinations to be found along a highway, the direction to travel, and the distance in miles ...

  8. Motion Segmentation of Truncated Signed Distance Function based Volumetric Samunda Perera, Nick Barnes, Xuming He

    E-Print Network [OSTI]

    Kohli, Pushmeet

    Motion Segmentation of Truncated Signed Distance Function based Volumetric Surfaces Samunda Perera. Introduction The Truncated Signed Distance Function (TSDF) based volumetric surface representation format [4 the problem of segmenting such a volumetric surface reconstruction of a scene into distinctively moving

  9. A colalborative environment for information driven safeguards

    SciTech Connect (OSTI)

    Scott, Mark R; Michel, Kelly D

    2010-09-15

    For two decades, the IAEA has recognized the need for a comprehensive and strongly integrated Knowledge Management system to support its Information Driven Safeguards activities. In the past, plans for the development of such a system have progressed slowly due to concerns over costs and feasibility. In recent years, Los Alamos National Laboratory has developed a knowledge management system that could serve as the basis for an IAEA Collaborative Environment (ICE). The ICE derivative knowledge management system described in this paper addresses the challenge of living in an era of information overload coupled with certain knowledge shortfalls. The paper describes and defines a system that is flexible, yet ensures coordinated and focused collaboration, broad data evaluation capabilities, architected and organized work flows, and improved communications. The paper and demonstration of ICE will utilize a hypothetical scenario to highlight the functional features that facilitate collaboration amongst and between information analysts and inspectors. The scenario will place these two groups into a simulated planning exercise for a safeguards inspection drawing upon past data acquisitions, inspection reports, analyst conclusions, and a coordinated walk-through of a 3-D model of the facility. Subsequent to the conduct of the simulated facility inspection, the detection of an anomaly and pursuit of follow up activities will illustrate the event notification, information sharing, and collaborative capabilities of the system. The use of a collaborative environment such as ICE to fulfill the complicated knowledge management demands of the Agency and facilitate the completion of annual State Evaluation Reports will also be addressed.

  10. Data flow machine for data driven computing

    DOE Patents [OSTI]

    Davidson, George S. (Albuquerque, NM); Grafe, Victor G. (Albuquerque, NM)

    1995-01-01

    A data flow computer which of computing is disclosed which utilizes a data driven processor node architecture. The apparatus in a preferred embodiment includes a plurality of First-In-First-Out (FIFO) registers, a plurality of related data flow memories, and a processor. The processor makes the necessary calculations and includes a control unit to generate signals to enable the appropriate FIFO register receiving the result. In a particular embodiment, there are three FIFO registers per node: an input FIFO register to receive input information form an outside source and provide it to the data flow memories; an output FIFO register to provide output information from the processor to an outside recipient; and an internal FIFO register to provide information from the processor back to the data flow memories. The data flow memories are comprised of four commonly addressed memories. A parameter memory holds the A and B parameters used in the calculations; an opcode memory holds the instruction; a target memory holds the output address; and a tag memory contains status bits for each parameter. One status bit indicates whether the corresponding parameter is in the parameter memory and one status but to indicate whether the stored information in the corresponding data parameter is to be reused. The tag memory outputs a "fire" signal (signal R VALID) when all of the necessary information has been stored in the data flow memories, and thus when the instruction is ready to be fired to the processor.

  11. Data flow machine for data driven computing

    DOE Patents [OSTI]

    Davidson, G.S.; Grafe, V.G.

    1988-07-22

    A data flow computer and method of computing is disclosed which utilizes a data driven processor node architecture. The apparatus in a preferred embodiment includes a plurality of First-In-First-Out (FIFO) registers, a plurality of related data flow memories, and a processor. The processor makes the necessary calculations and includes a control unit to generate signals to enable the appropriate FIFO register receiving the result. In a particular embodiment, there are three FIFO registers per node: an input FIFO register to receive input information from an outside source and provide it to the data flow memories; an output FIFO register to provide output information from the processor to an outside recipient; and an internal FIFO register to provide information from the processor back to the data flow memories. The data flow memories are comprised of four commonly addressed memories. A parameter memory holds the A and B parameters used in the calculations; an opcode memory holds the instruction; a target memory holds the output address; and a tag memory contains status bits for each parameter. One status bit indicates whether the corresponding parameter is in the parameter memory and one status bit to indicate whether the stored information in the corresponding data parameter is to be reused. The tag memory outputs a ''fire'' signal (signal R VALID) when all of the necessary information has been stored in the data flow memories, and thus when the instruction is ready to be fired to the processor. 11 figs.

  12. Designing and operating electrostatically driven microengines

    SciTech Connect (OSTI)

    Rodgers, M.S.; Sniegowski, J.J.; Miller, S.L.; LaVigne, G.F.

    1998-02-01

    Microelectromechanical engines that convert the linear outputs from dual orthogonal electrostatic actuators to rotary motion were first developed in 1993. Referred to as microengines, these early devices demonstrated the potential of microelectromechanical technology, but, as expected from any first-of-its-kind device, were not yet optimized. Yield was relatively low, and the 10 micronewtons of force generated by the actuators was not always enough to ensure reliable operation. Since initial development, these engines have undergone a continuous series of significant improvements on three separate fronts: design, fabrication, and electrical activation. Although all three areas will be discussed, emphasis will be on aspects related to mechanical design and generation of the electrical waveforms used to drive these devices. Microtransmissions that dramatically increase torque will also be discussed. Electrostatically driven microengines can be operated at hundreds of thousands of revolutions per minute making large gear reduction ratios feasible; overall ratios of 3,000,000:1 have been successfully demonstrated. Today`s microengines have evolved into high endurance (one test device has seen over 7,000,000,000 revolutions), high yield, robust devices that have become the primary actuation source for MicroElectroMechanical Systems (MEMS) at Sandia National Laboratories.

  13. Query-Driven Visualization and Analysis

    SciTech Connect (OSTI)

    Ruebel, Oliver; Bethel, E. Wes; Prabhat, Mr.; Wu, Kesheng

    2012-11-01

    This report focuses on an approach to high performance visualization and analysis, termed query-driven visualization and analysis (QDV). QDV aims to reduce the amount of data that needs to be processed by the visualization, analysis, and rendering pipelines. The goal of the data reduction process is to separate out data that is "scientifically interesting'' and to focus visualization, analysis, and rendering on that interesting subset. The premise is that for any given visualization or analysis task, the data subset of interest is much smaller than the larger, complete data set. This strategy---extracting smaller data subsets of interest and focusing of the visualization processing on these subsets---is complementary to the approach of increasing the capacity of the visualization, analysis, and rendering pipelines through parallelism. This report discusses the fundamental concepts in QDV, their relationship to different stages in the visualization and analysis pipelines, and presents QDV's application to problems in diverse areas, ranging from forensic cybersecurity to high energy physics.

  14. Review of Subcritical Source-Driven Noise Analysis Measurements

    SciTech Connect (OSTI)

    Valentine, T.E.

    1999-11-01

    Subcritical source-driven noise measurements are simultaneous Rossia and randomly pulsed neutron measurements that provide measured quantities that can be related to the subcritical neutron multiplication factor. In fact, subcritical source-driven noise measurements should be performed in lieu of Rossia measurements because of the additional information that is obtained from noise measurements such as the spectral ratio and the coherence functions. The basic understanding of source-driven noise analysis measurements can be developed from a point reactor kinetics model to demonstrate how the measured quantities relate to the subcritical neutron multiplication factor.

  15. Recap Dictionaries Wildcard queries Edit distance Spelling correction Soundex Introduction to Information Retrieval

    E-Print Network [OSTI]

    Nejdl, Wolfgang

    Dictionaries Wildcard queries Edit distance Spelling correction Soundex Skip pointers 16 28 72 5 51 98 2 4 8 16

  16. Type IIP supernovae as cosmological probes: A SEAM distance to SN 1999em

    E-Print Network [OSTI]

    Baron, E.; Nugent, Peter E.; Branch, David; Hauschildt, Peter H.

    2004-01-01

    Type IIP Supernovae as Cosmological Probes: A SEAM Distanceintrinsic brightness, supernovae make excellent cosmologicalstars: atmospheres — supernovae: 1999em Distances from

  17. On Dimensionality of Coordinate-Based Network Distance Mapping Technical Report

    E-Print Network [OSTI]

    Minnesota, University of

    observe "non-Euclidean-ness" in the network distance. We find that this "non-Euclidean- ness" is caused

  18. Multiple regression on distance matrices: a multivariate spatial analysis tool Jeremy W. Lichstein

    E-Print Network [OSTI]

    Lichstein, Jeremy W.

    Multiple regression on distance matrices: a multivariate spatial analysis tool Jeremy W. Lichstein, Spatial autocorrelation Abstract I explore the use of multiple regression on distance matrices (MRM regression of a response matrix on any number of explanatory matrices, where each matrix contains distances

  19. The UNIVERSITY of NORTH CAROLINA at CHAPEL HILL DiFi: Distance Fields -Fast

    E-Print Network [OSTI]

    North Carolina at Chapel Hill, University of

    The UNIVERSITY of NORTH CAROLINA at CHAPEL HILL DiFi: Distance Fields - Fast Computation Using UNIVERSITY of NORTH CAROLINA at CHAPEL HILL Distance Fields Distance Function For a site a scalar function f UNIVERSITY of NORTH CAROLINA at CHAPEL HILL What is a Voronoi Diagram? Given a collection of geometric

  20. Viral genome phylogeny based on LempelZiv complexity and Hausdorff distance

    E-Print Network [OSTI]

    Yu, Chenglong

    Viral genome phylogeny based on Lempel­Ziv complexity and Hausdorff distance Chenglong Yu a , Rong between two sequences. Use Hausdorff distance (HD) to analyze multi-segmented viral genomes. Use a modified Hausdorff distance (MHD) to analyze multi-segmented viral genomes. Take the multi

  1. Efficient Algorithms for Computing the Triplet and Quartet Distance Between Trees of Arbitrary Degree

    E-Print Network [OSTI]

    Schierup, Mikkel Heide

    Efficient Algorithms for Computing the Triplet and Quartet Distance Between Trees of Arbitrary- ficient algorithms for computing these distances. We show how to compute the triplet distance in time O against unresolved (non-binary) topologies. The previous best algorithm for computing the triplet

  2. Modeling Distance Decay for the Geographic Profiling Mike O'Leary

    E-Print Network [OSTI]

    O'Leary, Michael

    Modeling Distance Decay for the Geographic Profiling Problem Mike O'Leary Towson University Geospatial TWG Portland, OR April 15, 2010 Mike O'Leary (Towson University) Modeling distance decay 2010 commenting on a preliminary version of this presentation Mike O'Leary (Towson University) Modeling distance

  3. CS 5050 -Program #5 -30 points Edit Distance as Shortest Path Problem

    E-Print Network [OSTI]

    Allan, Vicki H.

    CS 5050 - Program #5 - 30 points Edit Distance as Shortest Path Problem Part 1 Edit Distance (15 be helpful: Write the edit distance program using a shortest path solution. To save you a little time points) Problems in molecular biology involve finding the minimum number of edit steps which are required

  4. A Test of the Calibration of the Tully-Fisher Relation Using Cepheid and SNIa Distances

    E-Print Network [OSTI]

    T. Shanks

    1997-02-18

    We make a direct test of Tully-Fisher distance estimates to eleven spiral galaxies with HST Cepheid distances and to twelve spiral galaxies with SNIa distances. The HST Cepheid distances come from the work of Freedman (1997), Sandage et al (1996) and Tanvir et al (1995). The SNIa distances come from Pierce (1994), calibrated using the Cepheid results of Sandage et al (1996). The Tully-Fisher distances mostly come from the work of Pierce (1994). The results show that the Tully-Fisher distance moduli are too short with respect to the Cepheid distances by 0.46+-0.14mag and too short with respect to the SNIa distances by 0.46+-0.19mag. Combining the HST Cepheid and SNIa data suggests that, overall, previous Tully-Fisher distances were too short by 0.46+-0.11mag, a result which is significant at the 4sigma level. These data therefore indicate that previous Tully-Fisher distances should be revised upwards by 24+-6% implying, for example, a Virgo distance of 19.3+-1.9Mpc. The value of Ho from Tully-Fisher estimates is correspondingly revised downwards from Ho=84+-10 to Ho=68+-8.

  5. Place Last Name First Name Gender Age Category Swim Yards Swim Distance Bike Distance Run Distance Overall Distance 1 Dykstra Andy M 18-24 1775.0 yards 1.009 miles 15.600 miles 3.790 miles 20.399 miles

    E-Print Network [OSTI]

    Thomas, David D.

    Place Last Name First Name Gender Age Category Swim Yards Swim Distance Bike Distance Run Distance.597 miles 12.300 miles 2.230 miles 15.127 miles 20 Strom Thad M 30-39 1150.0 yards 0.653 miles 12.000 miles

  6. How PseudoBoolean Programming can help Genome Rearrangement Distance Computation

    E-Print Network [OSTI]

    Fertin, Guillaume

    How Pseudo­Boolean Programming can help Genome Rearrangement Distance Computation S vialette@lri.fr Abstract. Computing genomic distances between whole genomes is a fundamental problem in comparative genomics. Recent researches have resulted in di#erent genomic distance definitions: number

  7. Web application creation made easy : a SQL-driven rapid development framework and a Do-It- Yourself platform

    E-Print Network [OSTI]

    Ong, Kian Win

    2010-01-01

    customization and evolution of such a database-driven webtomization and evolution of human-centric database-driven

  8. Mitsubishi iMiEV: An Electric Mini-Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2011-10-01

    This fact sheet highlights the Mitsubishi iMiEV, an electric mini-car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In support of the U.S. Department of Energy's fast-charging research efforts, NREL engineers are conducting charge and discharge performance testing on the vehicle. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

  9. Ultrafast dynamic ellipsometry of laser driven shock waves

    E-Print Network [OSTI]

    Bolme, Cynthia Anne

    2008-01-01

    The experimental measurement technique of ultrafast dynamic ellipsometry (UDE) was developed for measuring material motion and changes in optical properties of samples under laser driven shock loading. Ultrafast dynamic ...

  10. Re-entrant Lithium Local Environments and Defect Driven Electrochemist...

    Office of Scientific and Technical Information (OSTI)

    Lithium Local Environments and Defect Driven Electrochemistry of Li- and Mn-Rich Li-Ion Battery Cathodes Citation Details In-Document Search This content will become publicly...

  11. Chemically driven carbon-nanotube-guided thermopower waves

    E-Print Network [OSTI]

    Choi, Wonjoon

    Theoretical calculations predict that by coupling an exothermic chemical reaction with a nanotube or nanowire possessing a high axial thermal conductivity, a self-propagating reactive wave can be driven along its length. ...

  12. Innovation Methods in Story-Driven Games: Genre Variation

    E-Print Network [OSTI]

    Fernandez-Vara, Clara

    The paper proposes a method for game design innovation in story-driven games, as exemplified by the development of the adventure game prototype Rosemary. This method selects a game model in which a specific variation is ...

  13. Quantum-mechanical aspects of classically chaotic driven systems

    SciTech Connect (OSTI)

    Milonni, P.W.; Ackerhalt, J.R.; Goggin, M.E.

    1987-01-01

    This paper treats atoms and molecules in laser fields as periodically driven quantum systems. The paper concludes by determining that stochastic excitation is possible in quantum systems with quasiperiodic driving. 17 refs. (JDH)

  14. Analyzing aquifer driven reservoirs using a computer-oriented approach 

    E-Print Network [OSTI]

    Flumerfelt, Raymond William

    1996-01-01

    A new computer-oriented approach for analyzing aquifer driven reservoirs incorporates both geological and historical pressure data to determine original hydrocarbons-in-place and to forecast production. This new approach does not rely entirely...

  15. Analysis of consolidation around driven piles in overconsolidated clay

    E-Print Network [OSTI]

    Niarchos, Dimitrios G

    2012-01-01

    The principal objective of this thesis is to assess the capabilities of an already established analytical framework for understanding and predicting the behavior of piles driven in highly overconsolidated clays (OCR24). ...

  16. Numeric Bounds Analysis with Conflict-Driven Learning

    E-Print Network [OSTI]

    Kröning, Daniel

    and significantly outperforms floating- point decision procedures. 1 Introduction Automotive and avionic control analysis that embeds an abstract domain inside the Conflict Driven Clause Supported by the Toyota Motor

  17. Solar-Driven Microbial Photoelectrochemical System for Energy Conversion

    E-Print Network [OSTI]

    Wang, Hanyu

    2015-01-01

    S. S. , A Perspective on Solar-Driven Water Splitting withI. S. ; Kim, I. S. , A Solar-Powered Microbial ElectrolysisD. R. , Development of a Solar-Powered Microbial Fuel Cell.

  18. Development of NIR detectors and science driven requirements for SNAP

    E-Print Network [OSTI]

    2006-01-01

    Development of NIR Detectors and Science Driven Requirementshigh redshift. Ground based NIR observations su?er from anA dedicated optical and NIR space based instrument like SNAP

  19. Modeling buoyancy-driven airflow in ventilation shafts

    E-Print Network [OSTI]

    Ray, Stephen D. (Stephen Douglas)

    2012-01-01

    Naturally ventilated buildings can significantly reduce the required energy for cooling and ventilating buildings by drawing in outdoor air using non-mechanical forces. Buoyancy-driven systems are common in naturally ...

  20. Direct Visualization of Laser-Driven Focusing Shock Waves

    E-Print Network [OSTI]

    Pezeril, Thomas

    Direct real-time visualization and measurement of laser-driven shock generation, propagation, and 2D focusing in a sample are demonstrated. A substantial increase of the pressure at the convergence of the cylindrical ...

  1. Clustering of local group distances: publication bias or correlated measurements? I. The large Magellanic cloud

    SciTech Connect (OSTI)

    De Grijs, Richard [Kavli Institute for Astronomy and Astrophysics, Peking University, Yi He Yuan Lu 5, Hai Dian District, Beijing 100871 (China); Wicker, James E. [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Chaoyang District, Beijing 100012 (China); Bono, Giuseppe [Dipartimento di Fisica, Università di Roma Tor Vergata, via Della Ricerca Scientifica 1, I-00133 Roma (Italy)

    2014-05-01

    The distance to the Large Magellanic Cloud (LMC) represents a key local rung of the extragalactic distance ladder yet the galaxy's distance modulus has long been an issue of contention, in particular in view of claims that most newly determined distance moduli cluster tightly—and with a small spread—around the 'canonical' distance modulus, (m – M){sub 0} = 18.50 mag. We compiled 233 separate LMC distance determinations published between 1990 and 2013. Our analysis of the individual distance moduli, as well as of their two-year means and standard deviations resulting from this largest data set of LMC distance moduli available to date, focuses specifically on Cepheid and RR Lyrae variable-star tracer populations, as well as on distance estimates based on features in the observational Hertzsprung-Russell diagram. We conclude that strong publication bias is unlikely to have been the main driver of the majority of published LMC distance moduli. However, for a given distance tracer, the body of publications leading to the tightly clustered distances is based on highly non-independent tracer samples and analysis methods, hence leading to significant correlations among the LMC distances reported in subsequent articles. Based on a careful, weighted combination, in a statistical sense, of the main stellar population tracers, we recommend that a slightly adjusted canonical distance modulus of (m – M){sub 0} = 18.49 ± 0.09 mag be used for all practical purposes that require a general distance scale without the need for accuracies of better than a few percent.

  2. Observational evidence for travelling wave modes bearing distance proportional shifts

    E-Print Network [OSTI]

    Guruprasad, V

    2015-01-01

    Discrepancies of range between the Space Surveillance Network radars and the Deep Space Network in tracking the 1998 earth flyby of NEAR, and between ESA's Doppler and range data in Rosetta's 2009 flyby, reveal a consistent excess delay, or lag, equal to instantaneous one-way travel time in the telemetry signals. These lags readily explain all details of the flyby anomaly, and are shown to be symptoms of chirp d'Alembertian travelling wave solutions, relating to traditional sinusoidal waves by a rotation of the spectral decomposition due to the clock acceleration caused by the Doppler rates during the flybys. The lags thus relate to special relativity, but yield distance proportional shifts like those of cosmology at short range.

  3. Linking a distance measure of entanglement to its convex roof

    E-Print Network [OSTI]

    Alexander Streltsov; Hermann Kampermann; Dagmar Bruß

    2010-12-07

    An important problem in quantum information theory is the quantification of entanglement in multipartite mixed quantum states. In this work, a connection between the geometric measure of entanglement and a distance measure of entanglement is established. We present a new expression for the geometric measure of entanglement in terms of the maximal fidelity with a separable state. A direct application of this result provides a closed expression for the Bures measure of entanglement of two qubits. We also prove that the number of elements in an optimal decomposition w.r.t. the geometric measure of entanglement is bounded from above by the Caratheodory bound, and we find necessary conditions for the structure of an optimal decomposition.

  4. Linking a distance measure of entanglement to its convex roof

    E-Print Network [OSTI]

    Streltsov, Alexander; Bruß, Dagmar

    2010-01-01

    An important problem in quantum information theory is the quantification of entanglement in multipartite mixed quantum states. In this work a connection between the geometric measure of entanglement and a distance measure of entanglement is established. We present a new expression for the geometric measure of entanglement in terms of the maximal fidelity with a separable state. A direct application of this result provides a closed expression for the Bures measure of entanglement of two qubits. We also prove that the number of elements in an optimal decomposition with respect to the geometric measure of entanglement is bounded from above by the Caratheodory bound, and we find necessary conditions for the structure of an optimal decomposition.

  5. Consistency among distance measurements: transparency, BAO scale and accelerated expansion

    E-Print Network [OSTI]

    A. Avgoustidis; Licia Verde; Raul Jimenez

    2009-06-11

    We explore consistency among different distance measures, including Supernovae Type Ia data, measurements of the Hubble parameter, and determination of the Baryon acoustic oscillation scale. We present new constraints on the cosmic transparency combining $H(z)$ data together with the latest Supernova Type Ia data compilation. This combination, in the context of a flat $\\Lambda$CDM model, improves current constraints by nearly an order of magnitude. We re-examine the recently reported tension between the Baryon acoustic oscillation scale and Supernovae data in light of possible deviations from transparency, concluding that the source of the discrepancy may most likely be found among systematic effects of the modelling of the low redshift data or a simple $\\sim 2-\\sigma$ statistical fluke, rather than in exotic physics. Finally, we attempt to draw model-independent conclusions about the recent accelerated expansion, determining the acceleration redshift to be $z_{acc}=0.35^{+0.20}_{-0.13}$ (1-$\\sigma$).

  6. Ultrafast Long-Distance Quantum Communication with Static Linear Optics

    E-Print Network [OSTI]

    Fabian Ewert; Marcel Bergmann; Peter van Loock

    2015-03-23

    We propose a projection measurement onto encoded Bell states with a static network of linear optical elements. By increasing the size of the quantum error correction code, both Bell measurement efficiency and photon-loss tolerance can be made arbitrarily high at the same time. As a main application, we show that all-optical quantum communication over large distances with communication rates similar to those of classical communication is possible solely based on local state teleportations using optical sources of encoded Bell states, fixed arrays of beam splitters, and photon detectors discriminating up to two photons. As another application, generalizing state teleportation to gate teleportation for quantum computation, we find that in order to achieve universality the intrinsic loss tolerance must be sacrificed and a minimal amount of feedforward has to be added.

  7. Observational evidence for travelling wave modes bearing distance proportional shifts

    E-Print Network [OSTI]

    V. Guruprasad

    2015-07-18

    Discrepancies of range between the Space Surveillance Network radars and the Deep Space Network in tracking the 1998 earth flyby of NEAR, and between ESA's Doppler and range data in Rosetta's 2009 flyby, reveal a consistent excess delay, or lag, equal to instantaneous one-way travel time in the telemetry signals. These lags readily explain all details of the flyby anomaly, and are shown to be symptoms of chirp d'Alembertian travelling wave solutions, relating to traditional sinusoidal waves by a rotation of the spectral decomposition due to the clock acceleration caused by the Doppler rates during the flybys. The lags thus relate to special relativity, but yield distance proportional shifts like those of cosmology at short range.

  8. Distance measurements as a probe of cosmic acceleration

    E-Print Network [OSTI]

    Neil Trentham

    2001-05-23

    A major recent evelopment in observational cosmology has been an accurate measurement of the luminosity distance-redshift relation out to redshifts z=0.8 from Type Ia supernova standard candles. The results have been argued as evidence for cosmic acceleration. It is well known that this assertion depends on the assumption that we know the equation of state for all mass-energy other than normal pressureless matter; popular models are based on either the cosmological constant or on the more general quintessence formulation. But this assertion also depends on a number of other assumptions, implicit in the derivation of the standard cosmological field equations: large-scale isotropy and homogeneity, the flatness of the Universe, and the validity of general relativity on cosmological scales (where it has not been tested). A detailed examination of the effects of these assumptions on the interplay between the luminosity distance-redshift relation and the acceleration of the Universe is not possible unless one can define the precise nature of the failure of any particular assumption. However a simple quantitative investigation is possible and reveals a number of considerations about the relative importance of the different assumptions. In this paper we present such an investigation. We find that the relationship between the distant-redshift relation and the sign of the deceleration parameter is fairly robust and is unaffected if only one of the assumptions that we investigate is invalid so long as the deceleration parameter is not close to zero (it would not be close to zero in the currently-favored Omega_Lambda = 1 - Omega_matter = 0.7 or 0.8 Universe, for example). Failures of two or more assumptions in concordance may have stronger effects.

  9. A study of water driven oil encroachment into gas caps 

    E-Print Network [OSTI]

    Ritch, Harlan J

    1958-01-01

    A STUDY OF WATER DRIVEN OIL ENCROACHMENT INTO GAS CAPS LIBRARY A S I COLLEGE OF TEXAS A Thesis By HARLAN J. RITCH ~ ~ ~ Submitted to the Graduate School oi' the Agricultural and Mechanical College of Texas in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE May, 1958 Major Subject: Petroleum Engineering A STUDY OF WATER DRIVEN OIL ENCROACHMENT INTO GAS CAPS A Thesis By HARLAN J. RITCH Approved as to style and content by: hairxnan of Coxnxnittee) (Head...

  10. Nucleosynthesis of molybdenum in neutrino-driven winds

    E-Print Network [OSTI]

    Bliss, Julia

    2015-01-01

    Neutrino-driven winds that follow core-collapse supernovae are an exciting astrophysical site for the production of heavy elements. Although hydrodynamical simulations show that the conditions in the wind are not extreme enough for a r-process up to uranium, neutrino-driven winds may be the astrophysical site where lighter heavy elements between Sr an Ag are produced, either by the weak r-process or by the $\

  11. Evaluation of pumps for wind-driven irrigation. Final report

    SciTech Connect (OSTI)

    Marjon, P.L.; Clark, R.N.

    1982-11-01

    The report contains a survey of a variety of pumping equipment that can be used for wind power irrigation applications. Data are developed and sample results are presented on the economics of wind driven irrigation pumps as compared with other types of energy source-irrigation pump contributions. Conclusions are presented on the economics of wind driven irrigation pumps and suggestions are given for improving the economic potential.

  12. Science-Driven Computing: NERSC's Plan for 2006-2010

    SciTech Connect (OSTI)

    Simon, Horst D.; Kramer, William T.C.; Bailey, David H.; Banda,Michael J.; Bethel, E. Wes; Craw, James M.; Fortney, William J.; Hules,John A.; Meyer, Nancy L.; Meza, Juan C.; Ng, Esmond G.; Rippe, Lynn E.; Saphir, William C.; Verdier, Francesca; Walter, Howard A.; Yelick,Katherine A.

    2005-05-16

    NERSC has developed a five-year strategic plan focusing on three components: Science-Driven Systems, Science-Driven Services, and Science-Driven Analytics. (1) Science-Driven Systems: Balanced introduction of the best new technologies for complete computational systems--computing, storage, networking, visualization and analysis--coupled with the activities necessary to engage vendors in addressing the DOE computational science requirements in their future roadmaps. (2) Science-Driven Services: The entire range of support activities, from high-quality operations and user services to direct scientific support, that enable a broad range of scientists to effectively use NERSC systems in their research. NERSC will concentrate on resources needed to realize the promise of the new highly scalable architectures for scientific discovery in multidisciplinary computational science projects. (3) Science-Driven Analytics: The architectural and systems enhancements and services required to integrate NERSC's powerful computational and storage resources to provide scientists with new tools to effectively manipulate, visualize, and analyze the huge data sets derived from simulations and experiments.

  13. On the Steady Nature of Line-Driven Disk Winds

    E-Print Network [OSTI]

    Nicolas A. Pereyra; Stanley P. Owocki; D. John Hillier; David A. Turnshek

    2003-11-11

    We perform an analytic investigation of the stability of line-driven disk winds, independent of hydrodynamic simulations. Our motive is to determine whether or not line-driven disk winds can account for the wide/broad UV resonance absorption lines seen in cataclysmic variables (CVs) and quasi-stellar objects (QSOs). In both CVs and QSOs observations generally indicate that the absorption arising in the outflowing winds has a steady velocity structure on time scales exceeding years (for CVs) and decades (for QSOs). However, published results from hydrodynamic simulations of line-driven disk winds are mixed, with some researchers claiming that the models are inherently unsteady, while other models produce steady winds. The analytic investigation presented here shows that if the accretion disk is steady, then the line-driven disk wind emanating from it can also be steady. In particular, we show that a gravitational force initially increasing along the wind streamline, which is characteristic of disk winds, does not imply an unsteady wind. The steady nature of line-driven disk winds is consistent with the 1D streamline disk-wind models of Murray and collaborators and the 2.5D time-dependent models of Pereyra and collaborators. This paper emphasizes the underlying physics behind the steady nature of line-driven disk winds using mathematically simple models that mimic the disk environment

  14. Heat release and flame structure measurements of self-excited acoustically-driven premixed methane flames

    SciTech Connect (OSTI)

    Kopp-Vaughan, Kristin M.; Tuttle, Steven G.; Renfro, Michael W.; King, Galen B.

    2009-10-15

    An open-open organ pipe burner (Rijke tube) with a bluff-body ring was used to create a self-excited, acoustically-driven, premixed methane-air conical flame, with equivalence ratios ranging from 0.85 to 1.05. The feed tube velocities corresponded to Re = 1780-4450. Coupled oscillations in pressure, velocity, and heat release from the flame are naturally encouraged at resonant frequencies in the Rijke tube combustor. This coupling creates sustainable self-excited oscillations in flame front area and shape. The period of the oscillations occur at the resonant frequency of the combustion chamber when the flame is placed {proportional_to}1/4 of the distance from the bottom of the tube. In this investigation, the shape of these acoustically-driven flames is measured by employing both OH planar laser-induced fluorescence (PLIF) and chemiluminescence imaging and the images are correlated to simultaneously measured pressure in the combustor. Past research on acoustically perturbed flames has focused on qualitative flame area and heat release relationships under imposed velocity perturbations at imposed frequencies. This study reports quantitative empirical fits with respect to pressure or phase angle in a self-generated pressure oscillation. The OH-PLIF images were single temporal shots and the chemiluminescence images were phase averaged on chip, such that 15 exposures were used to create one image. Thus, both measurements were time resolved during the flame oscillation. Phase-resolved area and heat release variations throughout the pressure oscillation were computed. A relation between flame area and the phase angle before the pressure maximum was derived for all flames in order to quantitatively show that the Rayleigh criterion was satisfied in the combustor. Qualitative trends in oscillating flame area were found with respect to feed tube flow rates. A logarithmic relation was found between the RMS pressure and both the normalized average area and heat release rate for all flames. (author)

  15. Frequency-Sweeping Alfvén Instabilities Driven by Super-Alfvénic Beams in the Spherical Tokamak START

    E-Print Network [OSTI]

    Frequency-Sweeping Alfvén Instabilities Driven by Super-Alfvénic Beams in the Spherical Tokamak START

  16. Miniature lightweight x-ray optics (MiXO) for surface elemental composition mapping of asteroids and comets

    E-Print Network [OSTI]

    Hong, Jaesub

    2016-01-01

    The compositions of diverse planetary bodies are of fundamental interest to planetary science, providing clues to the formation and evolutionary history of the target bodies and the Solar system as a whole. Utilizing the X-ray fluorescence unique to each atomic element, X-ray imaging spectroscopy is a powerful diagnostic tool of the chemical and mineralogical compositions of diverse planetary bodies. Until now the mass and volume of focusing X-ray optics have been too large for resource-limited in-situ missions, so near-target X-ray observations of planetary bodies have been limited to simple collimator-type X-ray instruments. We introduce a new Miniature lightweight Wolter-I focusing X-ray Optics (MiXO) using metal-ceramic hybrid X-ray mirrors based on electroformed nickel replication and plasma thermal spray processes. MiXO can enable compact, powerful imaging X-ray telescopes suitable for future planetary missions. We illustrate the need for focusing X-ray optics in observing relatively small planetary bod...

  17. The Adjoint Method Applied to Time-Distance Helioseismology

    E-Print Network [OSTI]

    Shravan Hanasoge; Aaron Birch; Laurent Gizon; Jeroen Tromp

    2011-05-21

    For a given {\\it misfit function}, a specified optimality measure of a model, its gradient describes the manner in which one may alter properties of the system to march towards a stationary point. The adjoint method, arising from partial-differential-equation-constrained optimization, describes a means of extracting derivatives of a misfit function with respect to model parameters through finite computation. It relies on the accurate calculation of wavefields that are driven by two types of sources, namely the average wave-excitation spectrum, resulting in the {\\it forward wavefield}, and differences between predictions and observations, resulting in an {\\it adjoint wavefield}. All sensitivity kernels relevant to a given measurement emerge directly from the evaluation of an interaction integral involving these wavefields. The technique facilitates computation of sensitivity kernels (Fr\\'{e}chet derivatives) relative to three-dimensional heterogeneous background models, thereby paving the way for non-linear iterative inversions. An algorithm to perform such inversions using as many observations as desired is discussed.

  18. Performance of Gas-Engine Driven Heat Pump Unit

    SciTech Connect (OSTI)

    Abdi Zaltash; Randy Linkous; Randall Wetherington; Patrick Geoghegan; Ed Vineyard; Isaac Mahderekal; Robert Gaylord

    2008-09-30

    Air-conditioning (cooling) for buildings is the single largest use of electricity in the United States (U.S.). This drives summer peak electric demand in much of the U.S. Improved air-conditioning technology thus has the greatest potential impact on the electric grid compared to other technologies that use electricity. Thermally-activated technologies (TAT), such as natural gas engine-driven heat pumps (GHP), can provide overall peak load reduction and electric grid relief for summer peak demand. GHP offers an attractive opportunity for commercial building owners to reduce electric demand charges and operating expenses. Engine-driven systems have several potential advantages over conventional single-speed or single-capacity electric motor-driven units. Among them are variable speed operation, high part load efficiency, high temperature waste heat recovery from the engine, and reduced annual operating costs (SCGC 1998). Although gas engine-driven systems have been in use since the 1960s, current research is resulting in better performance, lower maintenance requirements, and longer operating lifetimes. Gas engine-driven systems are typically more expensive to purchase than comparable electric motor-driven systems, but they typically cost less to operate, especially for commercial building applications. Operating cost savings for commercial applications are primarily driven by electric demand charges. GHP operating costs are dominated by fuel costs, but also include maintenance costs. The reliability of gas cooling equipment has improved in the last few years and maintenance requirements have decreased (SCGC 1998, Yahagi et al. 2006). Another advantage of the GHP over electric motor-driven is the ability to use the heat rejected from the engine during heating operation. The recovered heat can be used to supplement the vapor compression cycle during heating or to supply other process loads, such as water heating. The use of the engine waste heat results in greater operating efficiency compared to conventional electric motor-driven units (SCGC 1998). In Japan, many hundreds of thousands of natural gas-driven heat pumps have been sold (typically 40,000 systems annually) (Yahagi et al. 2006). The goal of this program is to develop dependable and energy efficient GHPs suitable for U.S. commercial rooftop applications (the single largest commercial product segment). This study describes the laboratory performance evaluation of an integrated 10-ton GHP rooftop unit (a 900cc Daihatsu-Aisin natural gas engine) which uses R410A as the refrigerant (GEDAC No.23). ORNL Thermally-Activated Heat Pump (TAHP) Environmental Chambers were used to evaluate this unit in a controlled laboratory environment.

  19. Analysis of the Argonne distance tabletop exercise method.

    SciTech Connect (OSTI)

    Tanzman, E. A.; Nieves, L. A.; Decision and Information Sciences

    2008-02-14

    The purpose of this report is to summarize and evaluate the Argonne Distance Tabletop Exercise (DISTEX) method. DISTEX is intended to facilitate multi-organization, multi-objective tabletop emergency response exercises that permit players to participate from their own facility's incident command center. This report is based on experience during its first use during the FluNami 2007 exercise, which took place from September 19-October 17, 2007. FluNami 2007 exercised the response of local public health officials and hospitals to a hypothetical pandemic flu outbreak. The underlying purpose of the DISTEX method is to make tabletop exercising more effective and more convenient for playing organizations. It combines elements of traditional tabletop exercising, such as scenario discussions and scenario injects, with distance learning technologies. This distance-learning approach also allows playing organizations to include a broader range of staff in the exercise. An average of 81.25 persons participated in each weekly webcast session from all playing organizations combined. The DISTEX method required development of several components. The exercise objectives were based on the U.S. Department of Homeland Security's Target Capabilities List. The ten playing organizations included four public health departments and six hospitals in the Chicago area. An extent-of-play agreement identified the objectives applicable to each organization. A scenario was developed to drive the exercise over its five-week life. Weekly problem-solving task sets were designed to address objectives that could not be addressed fully during webcast sessions, as well as to involve additional playing organization staff. Injects were developed to drive play between webcast sessions, and, in some cases, featured mock media stories based in part on player actions as identified from the problem-solving tasks. The weekly 90-minute webcast sessions were discussions among the playing organizations that were moderated by a highly-qualified public health physician, who reviewed key scenario developments and player actions, as well as solicited input from each playing organization. The exercise control structure included trusted agents who oversaw exercise planning, playing organization points of contact to ensure exercise coordination, and exercise controller/evaluators to initiate and oversee exercise play. A password-protected exercise website was designed for FluNami 2007 to serve as a compartmentalized central information source, and for transmitting exercise documents. During the course of FluNami 2007, feedback on its quality was collected from players and controller/evaluators. Player feedback was requested at the conclusion of each webcast, upon completion of each problem-solving task, and on October 17, 2007, after the final webcast session had ended. The overall average score given to FluNami 2008 by the responding players was 3.9 on a five-point scale. In addition, suggestions for improving the process were provided by Argonne controller/evaluators after the exercise concluded. A series of recommendations was developed based on feedback from the players and controller/evaluators. These included improvements to the exercise scope and objectives, the problem-solving tasks, the scenarios, exercise control, the webcast sessions, the exercise website, and the player feedback process.

  20. Model for biological communication in a nanofabricated cell-mimic driven by stochastic resonance

    SciTech Connect (OSTI)

    Karig, David K [ORNL; Siuti, Piro [ORNL; Dar, Roy D. [University of Tennessee, Knoxville (UTK); Retterer, Scott T [ORNL; Doktycz, Mitchel John [ORNL; Simpson, Michael L [ORNL

    2011-01-01

    Cells offer natural examples of highly efficient networks of nanomachines. Accordingly, both intracellular and intercellular communication mechanisms in nature are looked to as a source of inspiration and instruction for engineered nanocommunication. Harnessing biological functionality in this manner requires an interdisciplinary approach that integrates systems biology, synthetic biology, and nanofabrication. Recent years have seen the amassing of a tremendous wealth of data from the sequencing of new organisms and from high throughput expression experiments. At the same time, a deeper fundamental understanding of individual cell function has been developed, as exemplified by the growth of fields such as noise biology, which seeks to characterize the role of noise in gene expression. The availability of well characterized biological components coupled with a deeper understanding of cell function has led to efforts to engineer both living cells and to create bio-like functionality in non-living substrates in the field of synthetic biology. Here, we present a model system that exemplifies the synergism between these realms of research. We propose a synthetic gene network for operation in a nanofabricated cell mimic array that propagates a biomolecular signal over long distances using the phenomenon of stochastic resonance. Our system consists of a bacterial quorum sensing signal molecule, a bistable genetic switch triggered by this signal, and an array of nanofabricated cell mimic wells that contain the genetic system. An optimal level of noise in the system helps to propagate a time-varying AHL signal over long distances through the array of mimics. This noise level is determined both by the system volume and by the parameters of the genetic network. Our proposed genetically driven stochastic resonance system serves as a testbed for exploring the potential harnessing of gene expression noise to aid in the transmission of a time-varying molecular signal.

  1. A Test of Tully-Fisher Distance Estimates Using Cepheids and Type Ia Supernovae

    E-Print Network [OSTI]

    T. Shanks

    1999-01-24

    We update and extend the results of Shanks (1997, MNRAS, 290, L77) by making a direct test of Tully-Fisher distance estimates to thirteen spiral galaxies with HST Cepheid distances and to ten spiral galaxies with Type Ia supernova (SNIa) distances. The results show that the Tully-Fisher distance moduli are too short with respect to the Cepheid distances by 0.46+-0.11mag and too short with respect to the SNIa distances by 0.49+-0.18mag. Combining the HST Cepheid and the best SNIa data suggests that, overall, previous Tully-Fisher distances at v~1000 kms-1 were too short by 0.43+-0.09mag, a result which is significant at the 4.6 sigma level. These data therefore indicate that previous Tully-Fisher distances should be revised upwards by 22+-5% implying, for example, a Virgo distance of 19.0+-1.8Mpc. The value of Ho from Tully-Fisher estimates is correspondingly revised downwards from Ho=84+-10kms-1Mpc-1 to Ho=69+-8kms-1Mpc-1. There is evidence that the Tully-Fisher relation at large distances is affected by Malmquist bias. In this case, we argue that Ho<50kms-1Mpc-1 cannot be ruled out by Tully-Fisher considerations.

  2. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9-digit WSU

  3. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · wayne · The Welcome Center · P. O. Box 2340 · 42 West Warren · Detroit, MI 48202-0340 3/2015 Student's First Name 9

  4. Office of Student Financial Aid The Welcome Center 42 West Warren P.O. Box 2340 Detroit, MI 48202-0340 313-577-2100 Fax: 313-577-6648

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Office of Student Financial Aid The Welcome Center · 42 West Warren · P.O. Box 2340 · Detroit, MI.O. Box 2340 · Detroit, MI 48202-0340 · 313-577-2100 · Fax: 313-577-6648 studentservice@wayne.edu · www

  5. Instantaneous Action at a Distance in a Holistic Universe

    E-Print Network [OSTI]

    B. G. Sidharth

    1998-12-01

    The early work of Lorentz, Abraham and others, evolved through the work of Fokker, Dirac and others to ultimately culminate in the Feynman- Wheeler direct action at a distance theory. However this theory has encountered certain conceptual difficulties like non-locality in time, self force of the electron, pre acceleration and the perfect absorption condition of Feynman and Wheeler, that is the instantaneous action of the remaining charges in the universe on the charge in question. More recently, Hoyle and Narlikar have resurrected this theory, but within the context of a Steady State or Quasi Steady State cosmology. They argue that the theory infact has a better standing than the generally accepted quantum theoretic description. In this article we consider a quantum theoretic description and a cosmology which parallels the Hoyle-Narlikar approach. This leads to a synthesis and justification of the Dirac and Feynman-Wheeler approaches, clarifying the conceptual problems in the process. We deduce a scenario with quantized space-time and a holistic cosmology, consistent with physical and astrophysical data. The non-locality is now seen to be meaningful within the minimum space-time intervals, as also the perfect absorption within the holistic description. Local realism, and the usual causal field theory are seen to have an underpinning of direct action. For example this is brought out by the virtual photons which mediate interactions in Quantum Electro Dynamics, and the emergence of the inverse square law in the above approach from a background Zero Point Field.

  6. DISTANCE AND KINEMATICS OF THE TW HYDRAE ASSOCIATION FROM PARALLAXES

    SciTech Connect (OSTI)

    Weinberger, Alycia J.; Boss, Alan P.; Anglada-Escude, Guillem

    2013-01-10

    From common proper motion and signatures of youth, researchers have identified about 30 members of a putative TW Hydrae Association. Only four of these had parallactic distances from Hipparcos. We have measured parallaxes and proper motions for 14 primary members. We combine these with literature values of radial velocities to show that the Galactic space motions of the stars, with the exception of TWA 9 and 22, are parallel and do not indicate convergence at a common formation point sometime in the last few million years. The space motions of TWA 9 and 22 do not agree with the others and indicate that they are not TWA members. The median parallax is 18 mas or 56 pc. We further analyze the stars' absolute magnitudes on pre-main-sequence evolutionary tracks and find a range of ages with a median of 10.1 Myr and no correlation between age and Galactic location. The TWA stars may have formed from an extended and filamentary molecular cloud but are not necessarily precisely coeval.

  7. Distance dependence of the phase signal in eddy current microscopy

    E-Print Network [OSTI]

    Roll, Tino; Fischer, Ulrich; Schleberger, Marika

    2008-01-01

    Atomic force microscopy using a magnetic tip is a promising tool for investigating conductivity on the nano-scale. By the oscillating magnetic tip eddy currents are induced in the conducting parts of the sample which can be detected in the phase signal of the cantilever. However, the origin of the phase signal is still controversial because theoretical calculations using a monopole appoximation for taking the electromagnetic forces acting on the tip into account yield an effect which is too small by more than two orders of magnitude. In order to determine the origin of the signal we used especially prepared gold nano patterns embedded in a non-conducting polycarbonate matrix and measured the distance dependence of the phase signal. Our data clearly shows that the interacting forces are long ranged and therefore, are likely due to the electromagnetic interaction between the magnetic tip and the conducting parts of the surface. Due to the long range character of the interaction a change in conductivity of $\\Del...

  8. Transition state theory for laser-driven reactions

    SciTech Connect (OSTI)

    Kawai, Shinnosuke; Bandrauk, Andre D.; Jaffe, Charles; Bartsch, Thomas; Palacian, Jesus; Uzer, T.

    2007-04-28

    Recent developments in transition state theory brought about by dynamical systems theory are extended to time-dependent systems such as laser-driven reactions. Using time-dependent normal form theory, the authors construct a reaction coordinate with regular dynamics inside the transition region. The conservation of the associated action enables one to extract time-dependent invariant manifolds that act as separatrices between reactive and nonreactive trajectories and thus make it possible to predict the ultimate fate of a trajectory. They illustrate the power of our approach on a driven Henon-Heiles system, which serves as a simple example of a reactive system with several open channels. The present generalization of transition state theory to driven systems will allow one to study processes such as the control of chemical reactions through laser pulses.

  9. Performance-Driven Interface Contract Enforcement for Scientific Components

    SciTech Connect (OSTI)

    Dahlgren, T L

    2007-10-01

    Performance-driven interface contract enforcement research aims to improve the quality of programs built from plug-and-play scientific components. Interface contracts make the obligations on the caller and all implementations of the specified methods explicit. Runtime contract enforcement is a well-known technique for enhancing testing and debugging. However, checking all of the associated constraints during deployment is generally considered too costly from a performance stand point. Previous solutions enforced subsets of constraints without explicit consideration of their performance implications. Hence, this research measures the impacts of different interface contract sampling strategies and compares results with new techniques driven by execution time estimates. Results from three studies indicate automatically adjusting the level of checking based on performance constraints improves the likelihood of detecting contract violations under certain circumstances. Specifically, performance-driven enforcement is better suited to programs exercising constraints whose costs are at most moderately expensive relative to normal program execution.

  10. Magneto-Centrifugal Launching of Jets from Accretion Disks. II: Inner Disk-Driven Winds

    E-Print Network [OSTI]

    Ruben Krasnopolsky; Zhi-Yun Li; Roger D. Blandford

    2003-06-25

    We follow numerically the time evolution of axisymmetric outflows driven magneto-centrifugally from the inner portion of accretion disks, from their launching surface to large, observable distances. Special attention is paid to the collimation of part of the outflow into a dense, narrow jet around the rotation axis, after a steady state has been reached. For parameters typical of T Tauri stars, we define a fiducial ``jet'' as outlined by the contour of constant density at 10^4 cm^{-3}. We find that the jet, so defined, appears nearly cylindrical well above the disk, in agreement with previous asymptotic analyses. Closer to the equatorial plane, the density contour can either bulge outwards or pinch inwards, depending on the conditions at the launching surface, particularly the mass flux distribution. We find that even though a dense, jet-like feature is always formed around the axis, there is no guarantee that the high-density axial jet would dominate the more tenuous, wide-angle part of the wind. Specifically, on the 100 AU scale, resolvable by HST and ground-based adaptive optics for nearby T Tauri winds, the fraction of the wind mass flux enclosed by the fiducial jet can vary substantially, again depending on the launching conditions. We show two examples in which the fraction is ~20% and ~45%. These dependences may provide a way to constrain the conditions at the launching surface, which are poorly known at present.

  11. 9 GeV Energy Gain in a Beam-Driven Plasma Wakefield Accelerator

    E-Print Network [OSTI]

    Litos, M; Allen, J M; An, W; Clarke, C I; Corde, S; Clayton, C E; Frederico, J; Gessner, S J; Green, S Z; Hogan, M J; Joshi, C; Lu, W; Marsh, K A; Mori, W B; Schmeltz, M; Vafaei-Najafabadi, N; Yakimenko, V

    2015-01-01

    An electron beam has gained a maximum energy of 9 GeV per particle in a 1.3 m-long electron beam-driven plasma wakefield accelerator. The amount of charge accelerated in the spectral peak was 28.3 pC, and the root-mean-square energy spread was 5.0%. The mean accelerated charge and energy gain per particle of the 215 shot data set was 115 pC and 5.3 GeV, respectively, corresponding to an acceleration gradient of 4.0 GeV/m at the spectral peak. The mean energy spread of the data set was 5.1%. These results are consistent with the extrapolation of the previously reported energy gain results using a shorter, 36 cm-long plasma source to within 10%, evincing a non-evolving wake structure that can propagate distances of over a meter in length. Wake-loading effects were evident in the data through strong dependencies observed between various spectral properties and the amount of accelerated charge.

  12. Spatial growth of the current-driven instability in relativistic jets

    SciTech Connect (OSTI)

    Mizuno, Yosuke; Hardee, Philip E.; Nishikawa, Ken-Ichi

    2014-04-01

    We investigated the influence of velocity shear and a radial density profile on the spatial development of the current-driven (CD) kink instability along helically magnetized relativistic jets via three-dimensional relativistic magnetohydrodynamic simulations. In this study, we use a nonperiodic computational box, the jet flow is initially established across the computational grid, and a precessional perturbation at the inlet triggers growth of the kink instability. If the velocity shear radius is located inside the characteristic radius of the helical magnetic field, a static nonpropagating CD kink is excited as the perturbation propagates down the jet. Temporal growth disrupts the initial flow across the computational grid not too far from the inlet. On the other hand, if the velocity shear radius is outside the characteristic radius of the helical magnetic field, the kink is advected with the flow and grows spatially down the jet. In this case, flow is maintained to much larger distances from the inlet. The effect of different radial density profiles is more subtle. When the density increases with radius, the kink appears to saturate by the end of the simulation without apparent disruption of the helical twist. This behavior suggests that relativistic jets consisting of a tenuous spine surrounded by a denser medium with a velocity shear radius outside the radius of the maximum toroidal magnetic field have a relatively stable configuration.

  13. Engines of culture : learning from the unique public realm of the long distance train

    E-Print Network [OSTI]

    Sherman, Danya

    2015-01-01

    The Long Distance American Train is a unique, meaningful, and somewhat mysterious site. These ephemeral, mobile societies exhibit remarkable qualities, including intensive interactions with strangers, conviviality amongst ...

  14. Anomalous expansion of the copper-apical-oxygen distance in supercondu...

    Office of Scientific and Technical Information (OSTI)

    Journal Article: Anomalous expansion of the copper-apical-oxygen distance in superconducting cuprate bilayers Citation Details In-Document Search Title: Anomalous expansion of the...

  15. Long distance symmetries for nuclear forces and the similarity renormalization group

    SciTech Connect (OSTI)

    Szpigel, S.; Timoteo, V. S.; Arriola, E. R.

    2013-03-25

    In this work we study the emergence of long distance symmetries for nuclear forces within the framework of the similarity renormalization group approach.

  16. Single-photon frequency upconversion for long-distance quantum teleportation and communication

    E-Print Network [OSTI]

    Albot?, Marius A., 1974-

    2006-01-01

    Entanglement generation, single-photon detection, and frequency translation that preserves the polarization quantum state of the photons are essential technologies for long distance quantum communication protocols. This ...

  17. Michigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    (30) CEM 141 General Chemistry 4 EGR 100 Introduction to Engineering Design 2 EGR 102 IntroductionMichigan State University | College of Engineering | Engineering Undergraduate Studies 1410 Engineering Building, East Lansing, MI 48824-1226 | (517) 355-6616 ext. 1 http

  18. 50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links

    E-Print Network [OSTI]

    Allen, Gale

    that broadcast with a power of 50,000 Watts day and night. Some of these stations are what was once known50,000-Watt AM Stations IA | MB | MI | MN | NE | ND | ON | SD | WI | Station News | Owners | TV Captures | Links 50,000-Watt AM stations This list includes AM stations in the United States and Canada

  19. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Feeny, Brian

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 Differential Equations Energy Systems 3 ME 422 Introduction to Combustion 3 ME 423 Intermed Mech of Deformable Solids 3 ME 425

  20. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http 234 Multivariable Calculus 4 MTH 235 Differential Equations 3 PHY 183 Physics for Scientists 450 International Environmental Law & Policy 3 ME 417 Design of Alternative Energy Systems 3 ME 422

  1. Michigan State University | College of Engineering | Engineering Undergraduate Studies Engineering Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1

    E-Print Network [OSTI]

    Building, 428 S. Shaw Lane, Room 1415, East Lansing MI 48824 | (517) 355-6616 ext. 1 http to Engineering Modeling 2 MTH 132 Calculus I 3 MTH 133 Calculus II 4 MTH 234 Multivariable Calculus 4 MTH 235 4 CEM 161 Chemistry Laboratory I 1 CHE 201 Materials and Energy Balances 3 ENE 280 Principles

  2. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema (OSTI)

    Tremblay, Julien [DOE JGI

    2013-01-25

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  3. Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 World Congress & Exposition, April 5, 2006, Detroit, MI

    E-Print Network [OSTI]

    Gruner, Sol M.

    Society of Automotive Engineers (SAE) Technical Paper 2006-01-1041 Paper presented at SAE 2006 and Fundamental Advances in Thermal Fluid Sciences 2006. Vol. SP-2015. (Society of Automotive Engineers, Troy, MI and reducing emissions play an essential role in the design of the new-generation automotive internal

  4. Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platform (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect (OSTI)

    Tremblay, Julien [DOE JGI] [DOE JGI

    2012-06-01

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  5. The ArgoNeuT Detector in the NuMI Low-Energy beam line at Fermilab

    E-Print Network [OSTI]

    C. Anderson; M. Antonello; B. Baller; T. Bolton; C. Bromberg; F. Cavanna; E. Church; D. Edmunds; A. Ereditato; S. Farooq; B. Fleming; H. Greenlee; R. Guenette; S. Haug; G. Horton-Smith; C. James; E. Klein; K. Lang; A. Lathrop; P. Laurens; S. Linden; D. McKee; R. Mehdiyev; B. Page; O. Palamara; K. Partyka; S. Pordes; G. Rameika; B. Rebel; B. Rossi; R. Sanders; M. Soderberg; J. Spitz; A. M. Szelc; M. Weber; T. Yang; T. Wongjirad; G. Zeller

    2012-06-05

    The ArgoNeuT liquid argon time projection chamber has collected thousands of neutrino and antineutrino events during an extended run period in the NuMI beam-line at Fermilab. This paper focuses on the main aspects of the detector layout and related technical features, including the cryogenic equipment, time projection chamber, read-out electronics, and off-line data treatment. The detector commissioning phase, physics run, and first neutrino event displays are also reported. The characterization of the main working parameters of the detector during data-taking, the ionization electron drift velocity and lifetime in liquid argon, as obtained from through-going muon data complete the present report.

  6. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nagarkar-Jaiswal, Sonal; Lee, Pei-Tseng; Campbell, Megan E.; Chen, Kuchuan; Anguiano-Zarate, Stephanie; Cantu Gutierrez, Manuel; Busby, Theodore; Lin, Wen-Wen; He, Yuchun; Schulze, Karen L.; et al

    2015-03-31

    Here, we document a collection of ~7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstratemore »reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates.« less

  7. Suppression of energetic particle driven instabilities with HHFW heating

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Fredrickson, E. D.; Taylor, G.; Bertelli, N.; Darrow, D. S.; Gorelenkov, N.; Kramer, G.; Liu, D.; Crocker, N. A.; Kubota, S.; White, R.

    2015-01-01

    In plasmas in the National Spherical Torus Experiment (NSTX) [Ono et al., Nucl. Fusion 40 (2000) 557] heated with neutral beams, the beam ions typically excite Energetic Particle Modes (EPMs or fishbones), and Toroidal, Global or Compressional Alfvén Eigenmodes (TAE, GAE, CAE). These modes can redistribute the energetic beam ions, altering the beam driven current profile and the plasma heating profile, or they may affect electron thermal transport or cause losses of the beam ions. In this paper we present experimental results where these instabilities, driven by the super-thermal beam ions, are suppressed with the application of High Harmonic Fastmore »Wave heating.« less

  8. Driven Morse oscillator: Classical chaos, quantum theory, and photodissociation

    SciTech Connect (OSTI)

    Goggin, M.E.; Milonni, P.W.

    1988-02-01

    We compare the classical and quantum theories of a Morse oscillator driven by a sinusoidal field, focusing attention on multiple-photon excitation and dissociation. In both the classical and quantum theories the threshold field strength for dissociation may be estimated fairly accurately on the basis of classical resonance overlap, and the classical and quantum results for the threshold are in good agreement except near higher-order classical resonances and quantum multiphoton resonances. We discuss the possibility of ''quantum chaos'' in such driven molecular systems and use the Morse oscillator to test the manifestations of classical resonance overlap suggested semiclassically.

  9. Delay-induced driven patterns in coupled Cayley tree networks

    E-Print Network [OSTI]

    Aradhana Singh; Sarika Jalan

    2013-04-04

    We study effects of delay in diffusively coupled logistic maps on the Cayley tree networks. We find that smaller coupling values exhibits sensitiveness for value of delay, and leads to different cluster patterns of self-organized and driven types. Whereas larger coupling strengths are very robust against change in delay values, and leads to stable driven clusters comprising only nodes from last generation of the Calaye tree. Furthermore, introduction of delay exhibits suppression as well as enhancement of synchronization depending upon coupling strength values, hence demonstrating richness of the model. To the end we relate the results with social conflicts and cooperation observed in families.

  10. Suppression of energetic particle driven instabilities with HHFW heating

    SciTech Connect (OSTI)

    Fredrickson, E. D.; Taylor, G.; Bertelli, N.; Darrow, D. S.; Gorelenkov, N.; Kramer, G.; Liu, D.; Crocker, N. A.; Kubota, S.; White, R.

    2015-01-01

    In plasmas in the National Spherical Torus Experiment (NSTX) [Ono et al., Nucl. Fusion 40 (2000) 557] heated with neutral beams, the beam ions typically excite Energetic Particle Modes (EPMs or fishbones), and Toroidal, Global or Compressional Alfvén Eigenmodes (TAE, GAE, CAE). These modes can redistribute the energetic beam ions, altering the beam driven current profile and the plasma heating profile, or they may affect electron thermal transport or cause losses of the beam ions. In this paper we present experimental results where these instabilities, driven by the super-thermal beam ions, are suppressed with the application of High Harmonic Fast Wave heating.

  11. Reconciliation of the Surface Brightness Fluctuations and Type Ia Supernovae Distance Scales

    E-Print Network [OSTI]

    Edward A. Ajhar; John L. Tonry; John P. Blakeslee; Adam G. Riess; Brian P. Schmidt

    2001-05-21

    We present Hubble Space Telescope measurements of surface brightness fluctuations (SBF) distances to early-type galaxies that have hosted Type Ia supernovae (SNIa). The agreement in the relative SBF and SNIa multicolor light curve shape and delta-m_15 distances is excellent. There is no systematic scale error with distance, and previous work has shown that SBF and SNIa give consistent ties to the Hubble flow. However, we confirm a systematic offset of about 0.25 mag in the distance zero points of the two methods, and we trace this offset to their respective Cepheid calibrations. SBF has in the past been calibrated with Cepheid distances from the H_0 Key Project team, while SNIa have been calibrated with Cepheid distances from the team composed of Sandage, Saha, and collaborators. When the two methods are calibrated in a consistent way, their distances are in superb agreement. Until the conflict over the ``long'' and ``short'' extragalactic Cepheid distances among many galaxies is resolved, we cannot definitively constrain the Hubble constant to better than about 10%, even leaving aside the additional uncertainty in the distance to the Large Magellanic Cloud, common to both Cepheid scales. However, recent theoretical SBF predictions from stellar population models favor the Key Project Cepheid scale, while the theoretical SNIa calibration lies between the long and short scales. In addition, while the current SBF distance to M31/M32 is in good agreement with the RR Lyrae and red giant branch distances, calibrating SBF with the longer Cepheid scale would introduce a 0.3 mag offset with respect to the RR Lyrae scale.

  12. Virtual Classroom Extension for Effective Distance Education Radu Dondera, Chun Jia, Voicu Popescu,

    E-Print Network [OSTI]

    Nita-Rotaru, Cristina

    1 Virtual Classroom Extension for Effective Distance Education Radu Dondera, Chun Jia, Voicu to deliver quality education remotely. The system relies exclusively on commodity components, therefore it can be deployed in any classroom to allow any course to offer distance education seats. Keywords I.3

  13. Calculations of protective action distance for toxic chemical spills using nomographs

    SciTech Connect (OSTI)

    Lee, L.G.; Vail, J.A.; Gibeault, G.L.

    1995-04-01

    This document was produced for emergency use following a spill of liquid gas or finely divided solid (<100 micron) toxic chemicals. The information on the next few pages was kept deliberately terse and is limited to data and graphic aids needed for calculation of plume distance (protective action distance). All supporting material is provided as Appendices.

  14. Energy Displays and Environmental Behavior: The Role of Social Values and Psychological Distance of Climate Change

    E-Print Network [OSTI]

    McAuley, Derek

    distance of climate change in these effects. Method Study 1 (N=370) was a cross-sectional study. Participants filled in measures of their values and goals, psychological distance of climate change, and environmental behaviors. Study 2 (N=120) was a web-based experiment. A pre-test at the point of recruitment

  15. MEASURING AN ERUPTIVE PROMINENCE AT LARGE DISTANCES FROM THE SUN. I. IONIZATION AND EARLY EVOLUTION

    E-Print Network [OSTI]

    Howard, Tim

    MEASURING AN ERUPTIVE PROMINENCE AT LARGE DISTANCES FROM THE SUN. I. IONIZATION AND EARLY EVOLUTION characteristics at it moves away from the Sun. The prominence reaches complete ionization, or at least a state for an accompanying paper that reports on measurements of the prominence at large distances from the Sun using

  16. TIME-DISTANCE HELIOSEISMOLOGY: NOISE ESTIMATION L. Gizon and A. C. Birch

    E-Print Network [OSTI]

    Gizon, Laurent

    TIME-DISTANCE HELIOSEISMOLOGY: NOISE ESTIMATION L. Gizon and A. C. Birch W. W. Hansen Experimental ABSTRACT As in global helioseismology, the dominant source of noise in time-distance helioseismology oscillations. Characterizing noise is important for the interpretation and inversion of time

  17. Portal-Based True-Distance Heuristics for Path Finding Meir Goldenberg

    E-Print Network [OSTI]

    Schaeffer, Jonathan

    Portal-Based True-Distance Heuristics for Path Finding Meir Goldenberg Information Systems. In this paper, we introduce a new TDH, the portal-based heuristic. The domain is partitioned into regions and portals between regions are identified. True distances be- tween all pairs of portals are stored and used

  18. An RFID Distance Bounding Gerhard P. Hancke and Markus G. Kuhn

    E-Print Network [OSTI]

    Hancke, Gerhard

    range Used to link an item or person to a location An RFID Distance Bounding Protocol ­ p. #12;Relay application layer security protocols An RFID Distance Bounding Protocol ­ p. #12;Relay attack demonstration Proxy Token 14443 A/B test card circuit Signal processing with discrete components Duplex RF link Proxy

  19. On the Impact of Energy Dissipation Model on Characteristic Distance in Wireless Networks

    E-Print Network [OSTI]

    Hossain, Ashraf

    2011-01-01

    In this paper we investigate the dependency of characteristic distance on energy dissipation model. Both the many-to-one and any-to-any communication paradigm have been presented for performance analysis. Characteristic distance has been derived for three different cases. This study will be useful for designing an energy-efficient wireless network where nodes are energy-constrained.

  20. Fast NJ-like algorithms to deal with incomplete distance matrices

    E-Print Network [OSTI]

    Criscuolo, Alexis; Gascuel, Olivier

    2008-03-26

    .0617 0.0687 0.0552 0.0555 0.074 20 0.0503 0.0600 0.0682 0.0560 0.0509 0.189 In the medium-level combination, distance matrices are directly estimated from each of the genes and then combined (using SDM) into the distance supermatrix. Topolological...

  1. Ages of globular clusters: breaking the age-distance degeneracy with the luminosity function

    E-Print Network [OSTI]

    Paolo Padoan; Raul Jimenez

    1996-03-14

    We extend our previous method to determine globular cluster ages using the luminosity function (Jimenez \\& Padoan 1996). We show that the luminosity function depends on both age and distance modulus and that it is possible to distinguish between the two. This method provides at the same time independent determinations of distance and age of a GC by simply counting the number of stars found inside specified luminosity bins. The main uncertainties in other traditional methods for determining GCs ages are absent (e.g. mixing length, color-$T_{\\rm eff}$ calibration, morphology of the color-magnitude diagram ). The distance modulus is the biggest uncertainty in determining the age of GCs. Here we show that the age can be determined with small uncertainty for any value of distance modulus using the LF and that the LF allows a determination of the distance modulus itself. This is explained by the fact that the luminosity function is affected by a change in distance-modulus in a way that is different from its time evolution. If GC stellar counts with statistical errors not larger than $3\\%$ are available, the age can be determined with an uncertainty of about 0.4 Gyr (independent of distance modulus, mixing length and color calibration) and the distance modulus with an uncertainty of about 0.04 mag.

  2. Bounds for the Distance Dependence of Correlation Functions of Entangled Photons in Waveguides

    E-Print Network [OSTI]

    Andrei Khrennikov; Borje Nilsson; Sven Nordebo; Igor Volovich

    2011-05-30

    The distance dependence of the probability of observing two photons in a waveguide is investigated. The Glauber correlation functions of the entangled photons in waveguides are considered and the spatial and temporal dependence of the correlation functions is evaluated. We derive upper bounds to the distance dependence of the probability of observing two photons. These inequalities should be possible to observe in experiments.

  3. StructuralHammingDistance Average SHD Results -Child -Sample Size 500

    E-Print Network [OSTI]

    Brown, Laura E.

    , and Hailfinder10 Networks. C22_complete_shd_results.tex; 5/08/2005; 16:24; p.2 #12;0 500 1000 1500 x MMHC OR1k=5 GES StructuralHammingDistance Average SHD Results - Child - Sample Size 500 Error Bars = +/- Std TPDA GES StructuralHammingDistance Average SHD Results - Child3 - Sample Size 500 Error Bars = +/- Std

  4. Choosing Good Distance Metrics and Local Planners for Probabilistic Roadmap Methods \\Lambda

    E-Print Network [OSTI]

    Dale, Lucia K.

    Choosing Good Distance Metrics and Local Planners for Probabilistic Roadmap Methods \\Lambda Nancy M evaluation of different distance metrics and local planners within the con­ text of probabilistic roadmap planners for use in motion planning methods, particularly probabilistic roadmap methods. Our study

  5. Internet TV: Implications for the long distance network A. M. Odlyzko

    E-Print Network [OSTI]

    Odlyzko, Andrew M.

    Internet TV: Implications for the long distance network A. M. Odlyzko AT&T Labs - Research amo TV to the Internet is likely to have little impact on the long distance network. The main reason of Internet backbones far beyond that required to carry all the broadcast TV signals. There will continue

  6. Fast Jacobi-type Algorithm for Computing Distances Between Linear Dynamical Systems

    E-Print Network [OSTI]

    Vidal, René

    Fast Jacobi-type Algorithm for Computing Distances Between Linear Dynamical Systems Nicolas D Jacobi-type algorithm that solves this problem. Each step of the algorithm is equivalent to finding, in this paper, we introduce a fast and accurate Jacobi-type algorithm for computing alignment distances. Our

  7. Transition Metal Dimer Internuclear Distances from Measured Force Constants Joseph L. Jules and John R. Lombardi*

    E-Print Network [OSTI]

    Lombardi, John R.

    Transition Metal Dimer Internuclear Distances from Measured Force Constants Joseph L. Jules distances, have been extended to the transition metal dimers to test which one gives the most accurate fit's and Guggenheimer's for the transition metal dimers. Although Pauling's rule gives the best results, the remarkable

  8. AN INTEGRATION TECHNOLOGY FOR LONG DISTANCE LOGISTICS AND SUPPLY CHAIN MANAGEMENT

    E-Print Network [OSTI]

    Peng, Yun

    1 AN INTEGRATION TECHNOLOGY FOR LONG DISTANCE LOGISTICS AND SUPPLY CHAIN MANAGEMENT Hyunbo Cho will continue to grow. That trade depends on many intercontinental, long-distance, logistics partners. Those) ensure interoperability among logistics applications; (2) provide shipment visibility to all trading

  9. Towards Model Driven Engineering of Plastic User Interfaces

    E-Print Network [OSTI]

    Towards Model Driven Engineering of Plastic User Interfaces Jean-Sébastien Sottet CLIPS of a same UI are to be produced for different platforms. The development of plastic user interfaces is even more demanding. In Human Computer Interaction, plasticity denotes the capacity of a UI to withstand

  10. Tool Support for Test-Driven Development Using Formal Specifications

    E-Print Network [OSTI]

    Peters, Dennis

    the developer writes a failing automated test case that defines a desired improvement or new function, then produces code to pass that test and finally refactors the new code to acceptable standards. The stepsTool Support for Test-Driven Development Using Formal Specifications Shadi Alawneh and Dennis

  11. Lab 6: Forced Harmonic Motion Driven harmonic oscillation

    E-Print Network [OSTI]

    Gustafsson, Torgny

    Lab 6: Forced Harmonic Motion Driven harmonic oscillation Example: Atomic force microscope watch, circuit, ... #12;A constant energy flow at steady state ( )F t dF Rx= - 0oin ut PP + = #12;Forced harmonic t - = + #12;Forced harmonic oscillation (cont.) ( ) ( ) ( ) 0 2 2 0 cos 2 sin cos cosF m

  12. Domain-Driven Data Mining: Challenges and Prospects

    E-Print Network [OSTI]

    Cao, Longbing

    in real- world smart decision making. To this end, domain-driven data mining (D3 M) has been proposed, which is supposed to enable smart business intelligence for smart decisions in production. If we by business people for seamless decision making. To bridge the gap and enhance real-world problem- solving

  13. Demand-Driven Construction of Structural Features in ILP

    E-Print Network [OSTI]

    Kramer, Stefan

    Demand-Driven Construction of Structural Features in ILP Stefan Kramer Institute for Computer features in a rather unspeci#12;c way. That is, they do not construct features \\on demand", but rather and feature construction episodes in or- der to construct structural features \\on demand". In a feature

  14. A Market-Driven Framework Towards Environmentally Sustainable Mobile Computing

    E-Print Network [OSTI]

    Namboodiri, Vinod

    A Market-Driven Framework Towards Environmentally Sustainable Mobile Computing Siny Joseph Arts role of mobile devices has resulted in recent work advocating environmental sustainability in mobile of mobile computing and communication devices. One "green" approach to meet both the goals of minimizing

  15. A Novel, Web-Driven Continuous Mining Steven J. Schafrik

    E-Print Network [OSTI]

    A Novel, Web-Driven Continuous Mining Simulator By Steven J. Schafrik and Michael Karmis Department geometry of operations as well as other constraints. This paper presents WebConSim, a newly developed, Web underground and open-pit mining operations. OBJECTIVES AND DESIGN OF THE NEW WEB- BASED SIMULATOR One

  16. Predicting Cancer-Specific Vulnerability via Data-Driven

    E-Print Network [OSTI]

    Ruppin, Eytan

    Resource Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic LethalityCancer Research UK, The Beatson Institute for Cancer Research, Switchback Road, Glasgow G61 1BD, Scotland the inhibition of each single gene is not. It can be harnessed to selectively treat cancer by identifying

  17. Shape Anchors for Data-Driven Multi-view Reconstruction

    E-Print Network [OSTI]

    Xiao, Jianxiong

    We present a data-driven method for building dense 3D reconstructions using a combination of recognition and multi-view cues. Our approach is based on the idea that there are image patches that are so distinctive that we ...

  18. Butterfly Floquet Spectrum in Driven SU(2) Systems

    SciTech Connect (OSTI)

    Wang Jiao [Temasek Laboratories, National University of Singapore, 117542 (Singapore); Department of Physics, Institute of Theoretical Physics and Astrophysics, Xiamen University, Xiamen 361005 (China); Gong Jiangbin [Department of Physics and Center of Computational Science and Engineering, National University of Singapore, 117542 (Singapore); NUS Graduate School for Integrative Sciences and Engineering, Singapore 117597 (Singapore)

    2009-06-19

    The Floquet spectrum of a class of driven SU(2) systems is shown to display a butterfly pattern with multifractal properties. The level crossing between Floquet states of the same parity or different parities is studied. The results are relevant to studies of fractal statistics, quantum chaos, coherent destruction of tunneling, and the validity of mean-field descriptions of Bose-Einstein condensates.

  19. Wind and saltation driven particle resuspension in a wind tunnel

    SciTech Connect (OSTI)

    Fairchild, C.I.; Tillery, M.I.; Wheat, L.D.; Redmond, D.J.

    1985-01-01

    To determine parameters of primary importance in wind and saltation driven resuspension of fine particles from surfaces, wind tunnel experiments were conducted to study the resuspension of small polydisperse particles (diameter <10 ..mu..m) by monodisperse saltation particles (diameter >80 ..mu..m). The experiments were designed to simulate the atmospheric boundary layer resuspension of fine particles. 3 refs., 1 tab.

  20. Adding Semantics to Data-Driven Paraphrasing Ellie Pavlick1

    E-Print Network [OSTI]

    Plotkin, Joshua B.

    minimal/significant husband/marry to found/party clean/cleanse tower/building boy/young girl oil/oil priceAdding Semantics to Data-Driven Paraphrasing Ellie Pavlick1 Johan Bos2 Malvina Nissim2 Charley (Figure 1). In contrast, data-driving paraphrasing typically sidesteps de- veloping a clear definition

  1. GRAVITY DRIVEN SHALLOW WATER MODELS FOR ARBITRARY TOPOGRAPHY

    E-Print Network [OSTI]

    Blömker, Dirk

    GRAVITY DRIVEN SHALLOW WATER MODELS FOR ARBITRARY TOPOGRAPHY FRANC¸OIS BOUCHUT AND MICHAEL over a general topography. A first model is valid for small slope variation, i.e. small curvature, and a second model is valid for arbitrary topography. In both cases no particular assumption is made

  2. SPEECH-DRIVEN AUTOMATIC FACIAL EXPRESSION SYNTHESIS* Elif Bozkurt1

    E-Print Network [OSTI]

    Erdem, Cigdem Eroglu

    SPEECH-DRIVEN AUTOMATIC FACIAL EXPRESSION SYNTHESIS* Elif Bozkurt1 , Çi÷dem Ero÷lu Erdem1 , Engin heads. The proposed system is speaker and language independent. We parameterize speech data with prosody and acceleration coefficients are used. HMM based classifier has lower recognition rates than the GMM based

  3. Target Feasibility Achievement in Enterprise-Driven Hierarchical Multidisciplinary Design

    E-Print Network [OSTI]

    Chen, Wei

    problem where decisions on product design and market strategies are made simultaneously. In practicalTarget Feasibility Achievement in Enterprise-Driven Hierarchical Multidisciplinary Design Harrison is used to set the right targets for the engineering design process that maximize utility

  4. Evaporatively Driven Convection in a Draining Soap Film

    E-Print Network [OSTI]

    Bush, John W.M.

    Evaporatively Driven Convection in a Draining Soap Film Submitted by Jan M. Skotheim and John W. M. Bush, MIT A soap film was created by dipping a rectangular wire frame of height 3.5 cm and width 15 cm was mounted in a vertical po- sition, and the film drained under the influence of gravity in an unsaturated

  5. Signal conict in spider webs driven by predators and prey

    E-Print Network [OSTI]

    Blackledge, Todd

    Signal con¯ict in spider webs driven by predators and prey Todd A. Blackledge Department silk designs, stabilimenta, in the centre of their webs. Stabilimenta can be highly visible signals to predators, warning them of the presence of a noxious, sticky silk web. However, stabilimenta can also

  6. Cost-Driven Autonomous Mobility Xiao Yan Deng

    E-Print Network [OSTI]

    Trinder, Phil

    Cost-Driven Autonomous Mobility by Xiao Yan Deng Submitted for the Degree of Doctor of Philosophy. AMPs periodically use a cost model to decide where to execute in a network. Unusually this form cost model, together with a validated instantiation and comparative performance results for four AMPs

  7. The investigation of high intensity laser driven micro neutron sources

    E-Print Network [OSTI]

    Ghoniem, Nasr M.

    , access to high temperature states of mat- ter capable of thermonuclear fusion and/or the effi- cientThe investigation of high intensity laser driven micro neutron sources for fusion materials. The application of fast pulse, high intensity lasers to drive low cost DT point neutron sources for fusion

  8. Pyrotechnic Modelling for the NSI Driven Pin Puller

    E-Print Network [OSTI]

    -Puller tests: Bement, Schimmel, et al. · Pyrotechnics chemistry: McLain, Conklin · NSI ignition study: Varghese), · Constant temperature vessel wall, · No wall friction, · Constant density solid pyrotechnic, · ConstantPyrotechnic Modelling for the NSI Driven Pin Puller Joseph M. Powers and Keith A. Gonthier

  9. The FASEB Journal Review Biomechanics-driven chondrogenesis: from embryo

    E-Print Network [OSTI]

    Athanasiou, Kyriacos

    The FASEB Journal · Review Biomechanics-driven chondrogenesis: from embryo to adult Donald J, University of California­Davis, Davis, California, USA ABSTRACT Biomechanics plays a pivotal role in ar degeneration. Informed by the prominent role of biomechanics, mechanical stimuli have been har- nessed

  10. Neutrino-driven wind simulations and nucleosynthesis of heavy elements

    E-Print Network [OSTI]

    A. Arcones; F. -K. Thielemann

    2012-07-11

    Neutrino-driven winds, which follow core-collapse supernova explosions, present a fascinating nuclear astrophysics problem that requires understanding advanced astrophysics simulations, the properties of matter and neutrino interactions under extreme conditions, the structure and reactions of exotic nuclei, and comparisons against forefront astronomical observations. The neutrino-driven wind has attracted vast attention over the last 20 years as it was suggested to be a candidate for the astrophysics site where half of the heavy elements are produced via the r-process. In this review, we summarize our present understanding of neutrino-driven winds from the dynamical and nucleosynthesis perspectives. Rapid progress has been made during recent years in understanding the wind with improved simulations and better micro physics. The current status of the fields is that hydrodynamical simulations do not reach the extreme conditions necessary for the r-process and the proton or neutron richness of the wind remains to be investigated in more detail. However, nucleosynthesis studies and observations point already to neutrino-driven winds to explain the origin of lighter heavy elements, such as Sr, Y, Zr.

  11. Model-Driven Process Configuration of Enterprise Systems*

    E-Print Network [OSTI]

    van der Aalst, Wil

    have been funded by SAP Research and Queensland University of Technology with the project "ModellingModel-Driven Process Configuration of Enterprise Systems* Alexander Dreiling, Michael Rosemann Queensland University of Technology Wil van der Aalst Eindhoven University of Technology Wasim Sadiq SAP

  12. Understanding Climate Change: A Data-Driven Approach

    E-Print Network [OSTI]

    Kuzmanovic, Aleksandar

    Understanding Climate Change: A Data-Driven Approach Alok Choudhary Northwestern University Use Cases: Extreme Events Prediction Climate-Meningitis OutlookNH Tropical Cyclone (TC) Activity West Forecasting NA Hurricane Tracks Slide 3 #12;Climate System Complexity Climate systems are complex

  13. Triboelectric-Generator-Driven Pulse Electrodeposition for Micropatterning

    E-Print Network [OSTI]

    Wang, Zhong L.

    Triboelectric-Generator-Driven Pulse Electrodeposition for Micropatterning Guang Zhu, Caofeng Pan, such as batteries. Here we demonstrate a novel and simple generator with extremely low cost for efficiently/deformation. Owing to the coupling of contact charging and electrostatic induction, electric generation was achieved

  14. Modeling of a detonation driven, linear electric generator facility

    E-Print Network [OSTI]

    Texas at Arlington, University of

    Modeling of a detonation driven, linear electric generator facility E.M. Braun, E. Baydar, and F demonstrated that a PDE can be used for power generation and may be more efficient than a deflagration that involve coupling a PDE with different systems to drive a generator and produce electricity [2, 3]. One

  15. Cost-Driven Autonomous Mobility Xiao Yan Deng

    E-Print Network [OSTI]

    Trinder, Phil

    mobile programs (AMPs) offer a novel decentralised load management technology where periodic use is made by moving live jobs across processors or clusters at run time to maintain balance. Load management housekeeping overheads. More problematic, dynamic load management is reactive and is driven by the need

  16. Viscoelastic Suppression of Gravity-Driven Counterflow Instability

    E-Print Network [OSTI]

    Katz, Jonathan I.

    : December 8, 2010) Abstract Attempts to achieve "top-kill" of flowing oil wells by pumping dense drilling in the gravity driven counterflow produces turbulence that breaks up the denser fluid into small droplets. Here;Dense fluids, i.e., mineral suspensions called "mud" [1, 2], are introduced into oil wells to provide

  17. Status of Directly Driven ICF University of Rochester

    E-Print Network [OSTI]

    NIF Polar Drive OMEGA Experiments 78° 45° 23.5° 30° (45°) 50° (45°) 23.5° 0 0 100 200 300 100 GtRH1-D San Ramon, CA 29 January 2011 #12;TC9179 Directly-driven ignition designs and IFE designs for the NIF on OMEGA ­ experiments are being designed to examine laser­plasma interactions for anticipated NIF

  18. Fast NarrowingDriven Partial Evaluation for Inductively Sequential Programs

    E-Print Network [OSTI]

    Vidal, Germán

    ). In this work, we introduce a faster partial evaluation scheme by ensuring the termination of the process evaluation---only contain finitely many different terms (and, thus, partial evaluation terminates). SinceFast Narrowing­Driven Partial Evaluation for Inductively Sequential Programs J. Guadalupe Ramos

  19. Oine narrowing-driven partial evaluation J. Guadalupe Ramos

    E-Print Network [OSTI]

    Vidal, Germán

    termination issues are addressed. Online partial evaluators are usually more pre- cise. However, this extra NPE scheme by ensuring termination oine. Of- ine partial evaluators proceed in two stages: the rstOine narrowing-driven partial evaluation J. Guadalupe Ramos Josep Silva Germán Vidal I.T. La

  20. Icelandic Data Driven Part of Speech Tagging Mark Dredze

    E-Print Network [OSTI]

    Dredze, Mark

    Icelandic Data Driven Part of Speech Tagging Mark Dredze Department of Computer and Information tagger to han- dle fine grained tagsets and improve over the best Icelandic POS tagger. Additionally, we. In this work we consider Icelandic, a language for which a linguistic rule-based method is the current state

  1. UNCORRECTED 2 Reduced raindrop-impact driven soil erosion

    E-Print Network [OSTI]

    Walter, M.Todd

    study were to 29see if infiltration influences soil erosion due to raindrop- 0022-1694/$ - see frontUNCORRECTED PROOF 2 Reduced raindrop-impact driven soil erosion 3 by infiltration 4 Jeffrey D transport; Infiltration; Shield formation; soil erosion; Rainfall impact; Deposition Summary We used

  2. Photo-driven Molecular Wankel Engine B$_{13}^+$

    E-Print Network [OSTI]

    Zhang, Jin; Sparta, Manuel; Alexandrova, Anastassia N

    2012-01-01

    We report a molecular Wankel motor, the dual-ring structure B13+, driven by circularly-polarized infrared electromagnetic radiation, under which a guided uni-directional rotation of the outer ring is achieved with rotational frequency of the order of 300 MHz.

  3. Holistic Data-Driven Diagnosis for Dependable Automotive Systems

    E-Print Network [OSTI]

    Rajkumar, Ragunathan "Raj"

    Holistic Data-Driven Diagnosis for Dependable Automotive Systems Patrick E. Lanigan Carnegie Mellon, emer- gent behavior will still appear at runtime in dependable automotive systems. Such behavior occurs The automotive industry has become steadily more reliant on software- intensive distributed systems to imple

  4. Transport in charged colloids driven by thermoelectricity Alois Wrger

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Transport in charged colloids driven by thermoelectricity Alois Würger CPMOH, Université Bordeaux 1 to a strong increase with temperature. The di¤erence of the heat of transport of co-ions and counterions gives rise to a thermoelectric ...eld that drives the colloid to the cold or to the warm, depending

  5. DDDM2007: Domain Driven Data Mining Longbing Cao

    E-Print Network [OSTI]

    Cao, Longbing

    DDDM2007: Domain Driven Data Mining Longbing Cao University of Technology Sydney, Australia lbcao of Technology Sydney, Australia {chengqi,yczhao}@it.uts.edu.au Graham Williams Australian Taxation Office, Australia Graham.Williams@togaware.com ABSTRACT Real-world data mining generally must consider and in- volve

  6. Towards Continuous Policy-driven Demand Response in Data Centers

    E-Print Network [OSTI]

    Shenoy, Prashant

    Towards Continuous Policy-driven Demand Response in Data Centers David Irwin, Navin Sharma, and Prashant Shenoy University of Massachusetts, Amherst {irwin,nksharma,shenoy}@cs.umass.edu ABSTRACT Demand response (DR) is a technique for balancing electricity sup- ply and demand by regulating power consumption

  7. Gaseous Detonation-Driven Fracture of Tubes Tong Wa Chao

    E-Print Network [OSTI]

    Barr, Al

    Gaseous Detonation-Driven Fracture of Tubes Thesis by Tong Wa Chao In Partial Fulfillment An experimental investigation of fracture response of aluminum 6061-T6 tubes under internal gaseous detonation of this particular traveling load and tube geometry produced fracture data not available before in the open

  8. Cerenkov Radiator Driven by a Superconducting RF Electron Gun

    SciTech Connect (OSTI)

    Poole, B R; Harris, J R

    2011-03-07

    The Naval Postgraduate School (NPS), Niowave, Inc., and Boeing have recently demonstrated operation of the first superconducting RF electron gun based on a quarter wave resonator structure. In preliminary tests, this gun has produced 10 ps long bunches with charge in excess of 78 pC, and with beam energy up to 396 keV. Initial testing occurred at Niowave's Lansing, MI facility, but the gun and diagnostic beam line are planned for installation in California in the near future. The design of the diagnostic beam line is conducive to the addition of a Cerenkov radiator without interfering with other beam line operations. Design and simulations of a Cerenkov radiator, consisting of a dielectric lined waveguide will be presented. The dispersion relation for the structure is determined and the beam interaction is studied using numerical simulations. The characteristics of the microwave radiation produced in both the short and long bunch regimes will be presented.

  9. Bioenergy Demand in a Market Driven Forest Economy (U.S. South...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bioenergy Demand in a Market Driven Forest Economy (U.S. South) Bioenergy Demand in a Market Driven Forest Economy (U.S. South) Breakout Session 1A: Biomass Feedstocks for the...

  10. Sub-100 ps laser-driven dynamic compression of solid deuterium...

    Office of Scientific and Technical Information (OSTI)

    Sub-100 ps laser-driven dynamic compression of solid deuterium with a 40 J laser pulse Citation Details In-Document Search Title: Sub-100 ps laser-driven dynamic compression...

  11. Motor-Driven Assembly of Dynamic Self-Healing Lipid Nanotube...

    Office of Scientific and Technical Information (OSTI)

    Motor-Driven Assembly of Dynamic Self-Healing Lipid Nanotube Networks. Citation Details In-Document Search Title: Motor-Driven Assembly of Dynamic Self-Healing Lipid Nanotube...

  12. THE DOMINANCE OF NEUTRINO-DRIVEN CONVECTION IN CORE-COLLAPSE...

    Office of Scientific and Technical Information (OSTI)

    THE DOMINANCE OF NEUTRINO-DRIVEN CONVECTION IN CORE-COLLAPSE SUPERNOVAE Citation Details In-Document Search Title: THE DOMINANCE OF NEUTRINO-DRIVEN CONVECTION IN CORE-COLLAPSE...

  13. Design and optimization of a bi-axial vibration-driven electromagnetic...

    Office of Scientific and Technical Information (OSTI)

    Design and optimization of a bi-axial vibration-driven electromagnetic generator Citation Details In-Document Search Title: Design and optimization of a bi-axial vibration-driven...

  14. Repression of miR-17-5p with elevated expression of E2F-1 and c-MYC in non-metastatic hepatocellular carcinoma and enhancement of cell growth upon reversing this expression pattern

    SciTech Connect (OSTI)

    El Tayebi, H.M.; Omar, K.; Hegy, S.; El Maghrabi, M.; El Brolosy, M. [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)] [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt); Hosny, K.A. [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt)] [Department of General Surgery, Faculty of Medicine, Cairo University, Cairo (Egypt); Esmat, G. [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt)] [Department of Endemic Medicine and Hepatology, Cairo University, Cairo (Egypt); Abdelaziz, A.I., E-mail: ahmed.abdel-aziz@guc.edu.eg [The Molecular Pathology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo (Egypt)

    2013-05-10

    Highlights: •The oncogenic miR-17-5p is downregulated in non-metastatic hepatocellular carcinoma patients. •E2F-1 and c-MYC transcripts are upregulated in non-metastatic HCC patients. •miR-17-5p forced overexpression inhibited E2F-1 and c-MYC expression in HuH-7 cells. •miR-17-5p mimicking increased HuH-7 cell growth, proliferation, migration and colony formation. •miR-17-5p is responsible for HCC progression among the c-MYC/E2F-1/miR-17-5p triad members. -- Abstract: E2F-1, c-MYC, and miR-17-5p is a triad of two regulatory loops: a negative and a positive loop, where c-MYC induces the expression of E2F-1 that induces the expression of miR-17-5p which in turn reverses the expression of E2F-1 to close the loop. In this study, we investigated this triad for the first time in hepatocellular carcinoma (HCC), where miR-17-5p showed a significant down-regulation in 23 non-metastatic HCC biopsies compared to 10 healthy tissues; however, E2F-1 and c-MYC transcripts were markedly elevated. Forced over-expression of miR-17-5p in HuH-7 cells resulted in enhanced cell proliferation, growth, migration and clonogenicity with concomitant inhibition of E2F-1 and c-MYC transcripts expressions, while antagomirs of miR-17-5p reversed these events. In conclusion, this study revealed a unique pattern of expression for miR-17-5p in non-metastatic HCC patients in contrast to metastatic HCC patients. In addition we show that miR-17-5p is the key player among the triad that tumor growth and spread.

  15. Observations of dust acoustic waves driven at high frequencies: Finite dust temperature effects and wave interference

    E-Print Network [OSTI]

    Merlino, Robert L.

    Observations of dust acoustic waves driven at high frequencies: Finite dust temperature effects An experiment has been performed to study the behavior of dust acoustic waves driven at high frequencies f 100 are observed--interference effects between naturally excited dust acoustic waves and driven dust acoustic waves

  16. Brownian molecular motors driven by rotation-translation coupling Brian Geislinger and Ryoichi Kawai*

    E-Print Network [OSTI]

    Kawai, Ryoichi

    Brownian molecular motors driven by rotation-translation coupling Brian Geislinger and Ryoichi Received 18 March 2006; published 18 July 2006 We investigated three models of Brownian motors which. This second model can be driven by a combination of a Brownian motor mechanism diffusion driven

  17. Gravity-Driven flow of evaporating thin liquid films over substrates with topography

    E-Print Network [OSTI]

    Jimack, Peter

    Gravity-Driven flow of evaporating thin liquid films over substrates with topography Gaskell, P. Abstract This paper considers gravity-driven flow of thin liquid films over substrates with topography of gravity-driven flow of thin liquid films over well defined topography, as indicated in Figure 1, in which

  18. Output Synchronization of Multi-Agent Systems with Event-Driven Communication: Communication Delay and

    E-Print Network [OSTI]

    Antsaklis, Panos

    Output Synchronization of Multi-Agent Systems with Event-Driven Communication: Communication Delay-Agent Systems with Event-Driven Communication: Communication Delay and Signal Quantization Han Yu, Student is an important extension of applying event-driven communication to control of multi-agent systems, especially

  19. Definition and Application of Proton Source Efficiency in Accelerator Driven Per Seltborg*

    E-Print Network [OSTI]

    Definition and Application of Proton Source Efficiency in Accelerator Driven Systems Per Seltborg-mail: per@neutron.kth.se #12;2 I. INTRODUCTION Accelerator Driven Systems (ADS) [1, 2, 3, 4] are being driven system (ADS), a new parameter, the proton source efficiency (*) is introduced. * represents

  20. Lightning-Driven Electric and Magnetic Fields Measured in the Stratosphere: Implications for Sprites

    E-Print Network [OSTI]

    Thomas, Jeremy N.

    Lightning-Driven Electric and Magnetic Fields Measured in the Stratosphere: Implications-Driven Electric and Magnetic Fields Measured in the Stratosphere: Implications for Sprites Jeremy Norman Thomas et al., 2004b], in which the lightning-driven electric and magnetic field changes were rare, while

  1. Design of Chinese HPSG Framework for Data-Driven Parsing Xiangli Wang

    E-Print Network [OSTI]

    Design of Chinese HPSG Framework for Data-Driven Parsing * Xiangli Wang a , Shunya Iwasawa languages. We aim at exploring a data-driven Chinese parser, by basing it on Head-driven Phrase Structure Grammar (HPSG). Unlike for English, there is still no available Chinese HPSG framework. As the first step

  2. On the Performance of Point Kinetics for the Analysis of Accelerator Driven Systems

    E-Print Network [OSTI]

    On the Performance of Point Kinetics for the Analysis of Accelerator Driven Systems M. Eriksson kinetics to describe dynamic processes in accelerator-driven systems (ADS) is investigated. Full three of accelerator-driven systems (ADS) for the purpose of incinerating long-lived radionuclides in high- level waste

  3. MODDO -A TAILORED DOCUMENTATION SYSTEM FOR MODEL-DRIVEN SOFTWARE DEVELOPMENT

    E-Print Network [OSTI]

    Baader, Franz

    Software Documentation, Model-Driven Software Development 1. INTRODUCTION Delivering high-quality softwareMODDO - A TAILORED DOCUMENTATION SYSTEM FOR MODEL-DRIVEN SOFTWARE DEVELOPMENT Matthias Heinrich SAP.knechtel@sap.com ABSTRACT In the last decade Model-Driven Software Development (MDSD) has become an established software

  4. Behaviour of the winter North Atlantic eddy-driven jet stream in the CMIP3 integrations

    E-Print Network [OSTI]

    Barnes, Elizabeth A.

    Behaviour of the winter North Atlantic eddy-driven jet stream in the CMIP3 integrations Abdel-Verlag Berlin Heidelberg 2012 Abstract A systematic analysis of the winter North Atlantic eddy-driven jet stream is associated with variations in the westerly eddy-driven jet stream. Extratropical weather and climate

  5. Libra: An Economy-Driven Job Scheduling System for Jahanzeb Sherwani, Nosheen Ali,

    E-Print Network [OSTI]

    Buyya, Rajkumar

    Libra: An Economy-Driven Job Scheduling System for Clusters Jahanzeb Sherwani, Nosheen Ali computational economy driven scheduling system called Libra, which has been designed to support allocation scheduler to the PBS (Portable Batch System) system. The scheduler offers market-based economy driven

  6. The Drug Ontology Project for Elsevier An RDF Architecture Enabling Thesaurus-Driven Data Integration

    E-Print Network [OSTI]

    van Harmelen, Frank

    The Drug Ontology Project for Elsevier An RDF Architecture Enabling Thesaurus-Driven Data. In this paper, we describe how DOPE allows thesaurus-driven access to heterogeneous and distributed data, based. The DOPE prototype * allows thesaurus- driven access to heterogeneous and distributed data, based

  7. Observation of Centrifugally Driven Interchange Instabilities in a Plasma Confined by a Magnetic Dipole

    E-Print Network [OSTI]

    Mauel, Michael E.

    Observation of Centrifugally Driven Interchange Instabilities in a Plasma Confined by a Magnetic) Centrifugally driven interchange instabilities are observed in a laboratory plasma confined by a dipole magnetic electrostatic dipole vortex [3] that transports mass, energy, and charge [4]. The centrifugally driven

  8. Simulation of e-cloud driven instability and its attenuation using a simulated feedback system in the CERN SPS

    E-Print Network [OSTI]

    Vay, J.-L.

    2011-01-01

    system for the attenuation of e-cloud driven instability”, Proceed- ings Particle Acceleratorsystem for electron cloud-driven instabilities in the CERN SPS”, Proceedings Particle Accelerator

  9. An Approximate Analytical Algorithm for Evaluating the Distances in a Dark Energy Dominated Universe

    E-Print Network [OSTI]

    T. Wickramasinghe

    2007-12-05

    The most recent cosmological observations indicate that the present universe is flat and vacuum dominated. In such a universe, the distance measurements are always difficult and involve numerical computations. In this paper, it is shown that the most fundamental distance measurement of cosmology, the luminosity distance, for such a universe can be obtained in an approximate analytical way with very small errors of less than 0.02% up to %z = 5$ for any value of vacuum energy. The analytical calculation is shown to be exceedingly efficient, as compared to the traditional numerical methods.

  10. LIMB-DARKENED RADIATION-DRIVEN WINDS FROM MASSIVE STARS

    SciTech Connect (OSTI)

    Cure, M.; Cidale, L.

    2012-10-01

    We calculated the influence of the limb-darkened finite-disk correction factor in the theory of radiation-driven winds from massive stars. We solved the one-dimensional m-CAK hydrodynamical equation of rotating radiation-driven winds for all three known solutions, i.e., fast, {Omega}-slow, and {delta}-slow. We found that for the fast solution, the mass-loss rate is increased by a factor of {approx}10%, while the terminal velocity is reduced about 10%, when compared with the solution using a finite-disk correction factor from a uniformly bright star. For the other two slow solutions, the changes are almost negligible. Although we found that the limb darkening has no effects on the wind-momentum-luminosity relationship, it would affect the calculation of synthetic line profiles and the derivation of accurate wind parameters.

  11. Optimal cooling of a driven artificial atom in dissipative environment

    E-Print Network [OSTI]

    Lingjie Du; Yang Yu

    2013-06-02

    We study microwave-driven cooling in a superconducting flux qubit subjected to environment noises. For the weak decoherence, our analytical results agree well with the experimental observations near the degeneracy point and show that the microwave amplitude for optimal cooling should depend linearly on the dc flux detuning. With the decoherence increasing, more vibrational degrees of freedom couple in, making the ordinary cooling method less effective or even fail. We propose an improved cooling method, which can eliminate the perturbation of additional vibrational degrees of freedom hence keep high efficiency even under the strong decoherence. Furthermore, we point out that the decoherence will modulate the frequency where microwave-driven Landau-Zener transition reaches maximum in both methods, displaying the feature of incoherent dynamics which is important for the optimal cooling of qubits and other quantum systems.

  12. Strongly driven nonlinear quantum optics in microring resonators

    E-Print Network [OSTI]

    Vernon, Z

    2015-01-01

    We present a detailed analysis of strongly driven spontaneous four-wave mixing in a lossy integrated microring resonator side-coupled to a channel waveguide. A nonperturbative, analytic solution within the undepleted pump approximation is developed for a cw pump input of arbitrary intensity. In the strongly driven regime self- and cross-phase modulation, as well as multi-pair generation, lead to a rich variety of power-dependent effects; the results are markedly different than in the low power limit. The photon pair generation rate, single photon spectrum, and joint spectral intensity (JSI) distribution are calculated. Splitting of the generated single photon spectrum into a doublet structure associated with both pump detuning and cross-phase modulation is predicted, as well as substantial narrowing of the generated signal and idler bandwidths associated with the onset of optical parametric oscillation at intermediate powers. Both the correlated and uncorrelated contributions to the JSI are calculated, and fo...

  13. Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

    E-Print Network [OSTI]

    Appert-Rolland, Cecile; Santen, Ludger

    2015-01-01

    Cells are strongly out-of-equilibrium systems driven by continuous energy supply. They carry out many vital functions requiring active transport of various ingredients and organelles, some being small, others being large. The cytoskeleton, composed of three types of filaments, determines the shape of the cell and plays a role in cell motion. It also serves as a road network for the so-called cytoskeletal motors. These molecules can attach to a cytoskeletal filament, perform directed motion, possibly carrying along some cargo, and then detach. It is a central issue to understand how intracellular transport driven by molecular motors is regulated, in particular because its breakdown is one of the signatures of some neuronal diseases like the Alzheimer. We give a survey of the current knowledge on microtubule based intracellular transport. We first review some biological facts obtained from experiments, and present some modeling attempts based on cellular automata. We start with background knowledge on the origi...

  14. Beam-driven acceleration in ultra-dense plasma media

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Shin, Young-Min

    2014-09-15

    Accelerating parameters of beam-driven wakefield acceleration in an extremely dense plasma column has been analyzed with the dynamic framed particle-in-cell plasma simulator, and compared with analytic calculations. In the model, a witness beam undergoes a TeV/m scale alternating potential gradient excited by a micro-bunched drive beam in a 1025 m-3 and 1.6 x 1028 m-3 plasma column. The acceleration gradient, energy gain, and transformer ratio have been extensively studied in quasi-linear, linear-, and blowout-regimes. The simulation analysis indicated that in the beam-driven acceleration system a hollow plasma channel offers 20 % higher acceleration gradient by enlarging the channel radius (r)more »from 0.2 ?p to 0.6 ?p in a blowout regime. This paper suggests a feasibility of TeV/m scale acceleration with a hollow crystalline structure (e.g. nanotubes) of high electron plasma density.« less

  15. Heat-exchange statistics in driven open quantum systems

    E-Print Network [OSTI]

    S. Gasparinetti; P. Solinas; A. Braggio; M. Sassetti

    2014-07-29

    As the dimensions of physical systems approach the nanoscale, the laws of thermodynamics must be reconsidered due to the increased importance of fluctuations and quantum effects. While the statistical mechanics of small classical systems is relatively well understood, the quantum case still poses challenges. Here we set up a formalism that allows to calculate the full probability distribution of energy exchanges between a periodically driven quantum system and a thermalized heat reservoir. The formalism combines Floquet theory with a generalized master equation approach. For a driven two-level system and in the long-time limit, we obtain a universal expression for the distribution, providing clear physical insight into the exchanged energy quanta. We illustrate our approach in two analytically solvable cases and discuss the differences in the corresponding distributions. Our predictions could be directly tested in a variety of systems, including optical cavities and solid-state devices.

  16. Relaxation of a qubit measured by a driven Duffing oscillator

    E-Print Network [OSTI]

    I. Serban; M. I. Dykman; F. K. Wilhelm

    2010-01-11

    We investigate the relaxation of a superconducting qubit for the case when its detector, the Josephson bifurcation amplifier, remains latched in one of its two (meta)stable states of forced vibrations. The qubit relaxation rates are different in different states. They can display strong dependence on the qubit frequency and resonant enhancement, which is due to quasienergy resonances. Coupling to the driven oscillator changes the effective temperature of the qubit.

  17. LIQUID BUTANE FILLED LOAD FOR A LINER DRIVEN PEGASUS EXPERIMENT

    SciTech Connect (OSTI)

    M.A. SALAZAR; W. ANDERSON; ET AL

    2001-06-01

    A hydrogen rich, low density liquid, contained within the internal volume of a cylindrical liner, was requested of the Polymers and Coatings Group (MST-7) of the Los Alamos Materials Science Division for one of the last liner driven experiments conducted on the Los Alamos Pegasus facility. The experiment was a continuation of the Raleigh-Taylor hydrodynamics series of experiments and associated liners that have been described previously [1,2].

  18. Liquid butane filled load for a liner driven Pegasus experiment.

    SciTech Connect (OSTI)

    Salazar, M. A.; Armijo, E. V.; Anderson, W. E.; Atchison, W. L.; Bartos, J. J.; Garcia, F.; Randolph, B.; Sheppard, M. G.; Stokes, J. L.

    2001-01-01

    A hydrogen rich, low density liquid, contained within the internal volume of a cylindrical liner, was requested of the Polymers and Coatings Group (MST-7) of the Los Alamos Materials Science Division for one of the last liner driven experiments conducted on the Los Alamos Pegasus facility. The experiment (Fig.1) was a continuation of the Raleigh-Taylor hydrodynamics series of experiments and associated liners that have been described previously.

  19. xtreme space weather storms are driven by solar activity, which

    E-Print Network [OSTI]

    Wheatland, Michael S.

    magnetic fields (with field strengths up to 3000 gauss, or 0.3 tesla) emerge into the overlying atmosphere://solarscience.msfc.nasa.gov/SunspotCycle.shtml #12;The magnetic fields are generated inside the Sun by a "solar dynamo" driven by solar rotation, or of magnitude 10­4 tesla) and predominantly of one sign at the north pole and predominantly the opposite sign

  20. Laser-direct-driven quasi-isentropic experiments on aluminum

    SciTech Connect (OSTI)

    Xue, Quanxi, E-mail: quanxixue@163.com [Research Center of Laser Fusion, China Academy of Engineering Physics, Mianyang 621900 (China); State Key Laboratory of Laser Interaction with Matter, Northwest Institute of Nuclear Technology, Xi'an 710024 (China); Wang, Zhebin; Jiang, Shaoen, E-mail: jiangshn@vip.sina.com; Wang, Feng [Research Center of Laser Fusion, China Academy of Engineering Physics, Mianyang 621900 (China); Ye, Xisheng; Liu, Jingru [State Key Laboratory of Laser Interaction with Matter, Northwest Institute of Nuclear Technology, Xi'an 710024 (China)

    2014-07-15

    Laser-direct-driven ramp compression experiments were performed on long temporally shaped laser pulses based on an analytical isentropic compression model. Upper pressure limits, the ablation pressure scaling law, and stress-density curves were studied. The validity of the analytical model used, the ablation pressure scaling law, and the phenomena of missing line-imaging velocity interferometer (VISAR) fringes in the experimental results are discussed.