National Library of Energy BETA

Sample records for dispenser labeling requirement

  1. NGV fueling station technology program: CNG dispenser development goals. Interim report, February-June 1994

    SciTech Connect (OSTI)

    Svedeman, S.J.; Buckingham, J.C.; Behring, K.A.; McKee, R.J.

    1994-09-01

    The objective of the project is to investigate improvements to the CNG dispensers used at fueling stations. CNG dispensers perform similar functions to gasoline dispensers in that they control the fuel flow, measure the amount of fuel dispensed into the vehicle, and compute the sale amount. The specific areas where improvements are required include: reducing the dispenser cost, improving the dispensed gas flow measurement accuracy, reducing the time required to fill the vehicle, and increasing the level of fill provided by the dispenser control system.

  2. Tagging or Not?--The Constitutionality of Federal Labeling Requirements for Internet Web Pages

    E-Print Network [OSTI]

    Penabad, Coralee

    1998-01-01

    U.S. 726, 748 (1978). WEB PAGE LABELING fled the restrictionstatute only requires the web page composer to label thedoes not restrict what the web page composer writes nor what

  3. Micromachined chemical jet dispenser

    DOE Patents [OSTI]

    Swierkowski, S.P.

    1999-03-02

    A dispenser is disclosed for chemical fluid samples that need to be precisely ejected in size, location, and time. The dispenser is a micro-electro-mechanical systems (MEMS) device fabricated in a bonded silicon wafer and a substrate, such as glass or silicon, using integrated circuit-like fabrication technology which is amenable to mass production. The dispensing is actuated by ultrasonic transducers that efficiently produce a pressure wave in capillaries that contain the chemicals. The 10-200 {micro}m diameter capillaries can be arranged to focus in one spot or may be arranged in a larger dense linear array (ca. 200 capillaries). The dispenser is analogous to some ink jet print heads for computer printers but the fluid is not heated, thus not damaging certain samples. Major applications are in biological sample handling and in analytical chemical procedures such as environmental sample analysis, medical lab analysis, or molecular biology chemistry experiments. 4 figs.

  4. Micromachined chemical jet dispenser

    DOE Patents [OSTI]

    Swierkowski, Steve P. (Livermore, CA)

    1999-03-02

    A dispenser for chemical fluid samples that need to be precisely ejected in size, location, and time. The dispenser is a micro-electro-mechanical systems (MEMS) device fabricated in a bonded silicon wafer and a substrate, such as glass or silicon, using integrated circuit-like fabrication technology which is amenable to mass production. The dispensing is actuated by ultrasonic transducers that efficiently produce a pressure wave in capillaries that contain the chemicals. The 10-200 .mu.m diameter capillaries can be arranged to focus in one spot or may be arranged in a larger dense linear array (.about.200 capillaries). The dispenser is analogous to some ink jet print heads for computer printers but the fluid is not heated, thus not damaging certain samples. Major applications are in biological sample handling and in analytical chemical procedures such as environmental sample analysis, medical lab analysis, or molecular biology chemistry experiments.

  5. Apparatus for dispensing material

    DOE Patents [OSTI]

    Sutter, Peter Werner (Beach, NY); Sutter, Eli Anguelova (Beach, NY)

    2011-07-05

    An apparatus capable of dispensing drops of material with volumes on the order of zeptoliters is described. In some embodiments of the inventive pipette the size of the droplets so dispensed is determined by the size of a hole, or channel, through a carbon shell encapsulating a reservoir that contains material to be dispensed. The channel may be formed by irradiation with an electron beam or other high-energy beam capable of focusing to a spot size less than about 5 nanometers. In some embodiments, the dispensed droplet remains attached to the pipette by a small thread of material, an atomic scale meniscus, forming a virtually free-standing droplet. In some embodiments the droplet may wet the pipette tip and take on attributes of supported drops. Methods for fabricating and using the pipette are also described.

  6. Methods for dispensing mercury into devices

    DOE Patents [OSTI]

    Grossman, M.W.; George, W.A.

    1987-04-28

    A process is described for dispensing mercury into devices which requires mercury. Mercury is first electrolytically separated from either HgO or Hg[sub 2]Cl[sub 2] and plated onto a cathode wire. The cathode wire is then placed into a device requiring mercury. 2 figs.

  7. Room Temperature Dispenser Photocathode Using Elemental Cesium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Room Temperature Dispenser Photocathode Using Elemental Cesium Room Temperature Dispenser Photocathode Using Elemental Cesium Los Alamos National Laboratory (LANL) researchers have...

  8. E85 Dispenser Study

    SciTech Connect (OSTI)

    Moriarty, K.; Johnson, C.; Sears, T.; Bergeron, P.

    2009-12-01

    This study reviews E85 dispensing infrastructure advances and issues and evaluates the geographic concentration of flexible fuel vehicles (FFVs), E85 stations, ethanol production facilities, and E85 suppliers. Costs, space, financial incentives, and barriers to adding E85 fueling equipment at existing stations are also assessed. This study found that E85 is increasingly available in the U.S. in half of the states; however, the other half have minimal or no E85 fueling options. Despite these gains, E85 is only available at 1% of U.S. gasoline stations. Ethanol production reached 9.5 billion gallons in 2008, but less than 1% is consumed as E85. FFVs have not reached a significant concentration in any county, metropolitan area, or state.

  9. Regulations, Codes, and Standards (RCS) Template for California Hydrogen Dispensing Stations

    SciTech Connect (OSTI)

    Rivkin, C.; Blake, C.; Burgess, R.; Buttner, W.; Post, M.

    2012-11-01

    This report explains the Regulations, Codes, and Standards (RCS) requirements for hydrogen dispensing stations in the State of California. The reports shows the basic components of a hydrogen dispensing station in a simple schematic drawing; the permits and approvals that would typically be required for the construction and operation of a hydrogen dispensing station; and a basic permit that might be employed by an Authority Having Jurisdiction (AHJ).

  10. Milk dispenser for variable fat content

    E-Print Network [OSTI]

    Henion, Julie E

    2011-01-01

    This thesis describes the development of a new milk dispenser product that is designed to dispense milk with varying levels of milk fat content. The product contains two tanks of milk, one containing skim and one containing ...

  11. Hydrogen Compression, Storage, and Dispensing Cost Reduction...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Publications 2013 Hydrogen Compression, Storage, and Dispensing Cost Reduction Workshop Final Report Storage - Challenges and Opportunities Hydro-Pac Inc., A High Pressure Company...

  12. 2013 Hydrogen Compression, Storage, and Dispensing Cost Reduction...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    3 Hydrogen Compression, Storage, and Dispensing Cost Reduction Workshop Final Report 2013 Hydrogen Compression, Storage, and Dispensing Cost Reduction Workshop Final Report...

  13. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    using dispenser printing including (a) 3D polymer molds, (b)using dispenser printing including (a) 3D polymer molds, (b)

  14. Dispensing Equipment Testing With Mid-Level Ethanol/Gasoline...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Dispensing Equipment Testing With Mid-Level EthanolGasoline Test Fluid Dispensing Equipment Testing With Mid-Level EthanolGasoline Test Fluid The National Renewable Energy...

  15. System for Dispensing a Precise Amount of Fluid

    DOE Patents [OSTI]

    Benett, William J. (Livermore, CA); Krulevitch, Peter A. (Pleasanton, CA); Visuri, Steven R. (Livermore, CA); Dzenitis, John M. (Danville, CA); Ness, Kevin D. (Mountain View, CA)

    2008-08-12

    A dispensing system delivers a precise amount of fluid for biological or chemical processing and/or analysis. Dispensing means moves the fluid. The dispensing means is operated by a pneumatic force. Connection means delivers the fluid to the desired location. An actuator means provides the pneumatic force to the dispensing means. Valving means transmits the pneumatic force from the actuator means to the dispensing means.

  16. Hazard Communication Standard Pictogram As of June 1, 2015, the Hazard Communication Standard (HCS) will require pictograms on labels to alert users of the chemical

    E-Print Network [OSTI]

    Hazard Communication Standard Pictogram As of June 1, 2015, the Hazard Communication Standard (HCS) will require pictograms on labels to alert users of the chemical hazards to which they may be exposed. Each hazard(s). The pictogram on the label is determined by the chemical hazard classification. HCS Pictograms

  17. Automated Fuel Dispensing System Form Instructions

    E-Print Network [OSTI]

    Marques, Oge

    Automated Fuel Dispensing System Form Instructions If additional forms are necessary to provide(s) are hired and will be obtaining fuel, an Add Driver Form MUST be submitted for entry into the web database and/or diesel fuel to operate. Note: When a new vehicle, golf cart (gasoline), etc., is placed

  18. Alternative Fuels Data Center: Blender Pump Dispensers

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlender Pump Dispensers to someone by E-mail Share

  19. NREL UL Fuel Dispensing Infrastructure Intermediate Blends Performance Testing (Presentation)

    SciTech Connect (OSTI)

    Moriarty, K.; Clark, W.

    2011-01-01

    Presentation provides an overview of NREL's project to determine compatibility and safe performance of installed fuel dispensing infrastructure with E15.

  20. Plasma processes inside dispenser hollow cathodes

    SciTech Connect (OSTI)

    Mikellides, Ioannis G.; Katz, Ira; Goebel, Dan M.; Polk, James E.; Jameson, Kristina K.

    2006-06-15

    A two-dimensional fluid model of the plasma and neutral gas inside dispenser orificed hollow cathodes has been developed to quantify plasma processes that ultimately determine the life of the porous emitters inserted in these devices. The model self-consistently accounts for electron emission from the insert as well as for electron and ion flux losses from the plasma. Two cathodes, which are distinctively different in size and operating conditions, have been simulated numerically. It is found that the larger cathode, with outer tube diameter of 1.5 cm and orifice diameter of 0.3 cm, establishes an effective emission zone that spans approximately the full length of the emitter when operated at a discharge current of 25 A and a flow rate of 5.5 sccm. The net heating of the emitter is caused by ions that are produced by ionization of the neutral gas inside the tube and are then accelerated by the sheath along the emitter. The smaller cathode, with an outer diameter of 0.635 cm and an orifice diameter of 0.1 cm, does not exhibit the same operational characteristics. At a flow rate of 4.25 sccm and discharge current of 12 A, the smaller cathode requires 4.5 times the current density near the orifice and operates with more than 6 times the neutral particle density compared to the large cathode. As a result, the plasma particle density is almost one order of magnitude higher compared to the large cathode. The plasma density in this small cathode is high enough such that the Debye length is sufficiently small to allow 'sheath funneling' into the pores of the emitter. By accessing areas deeper into the insert material, it is postulated that the overall emission of electrons is significantly enhanced. The maximum emission current density is found to be about 1 A/mm{sup 2} in the small cathode, which is about one order of magnitude higher than attained in the large cathode. The effective emission zone in the small cathode extends to about 15% of the emitter length only, and the power deposited at the emitter surface by returning electrons is found to be twice that deposited by ions. A previous study suggested that the computed particle flux and energy of ions to the emitter of the 1.5 cm cathode were not high enough to change the barium evaporation rate compared to thermally induced evaporation. The same suggestion is made here for the 0.635 cm cathode. The peak ion flux to the emitter is found to be 1.2 A/cm{sup 2} (7.6x10{sup 18}/s cm{sup 2}), and the corresponding peak sheath drop is 2.9 V. Consequently, once the emitter operating temperature is known it is possible to determine directly the barium depletion-limited life of these cathodes using existing vacuum-cathode data.

  1. LABELLED DEDUCTION LABELLED DEDUCTION

    E-Print Network [OSTI]

    Balat, Vincent - Laboratoire Preuves, Programmes et Systèmes, Université Paris 7

    LABELLED DEDUCTION #12;#12;LABELLED DEDUCTION Edited by DAVID BASIN University of Freiburg MARCELLO;#12;Introduction David Basin, Marcello D'Agostino, Dov M. Gabbay, Se´an Matthews, Luca Vigan`o TO BE WRITTEN vii Sup´erieure 45, rue d'Ulm 75005, Paris, France Vincent.Balat@ens.fr Didier Galmiche LORIA UMR 7503

  2. LABELLED DEDUCTION LABELLED DEDUCTION

    E-Print Network [OSTI]

    Balat, Vincent - Laboratoire Preuves, Programmes et Systèmes, Université Paris 7

    LABELLED DEDUCTION #12; #12; LABELLED DEDUCTION Edited by DAVID BASIN University of Freiburg of ... v #12; #12; Introduction David Basin, Marcello D'Agostino, Dov M. Gabbay, Se?? an Matthews, Luca Balat Ecole Normale Sup?? erieure 45, rue d'Ulm 75005, Paris, France Vincent.Balat@ens.fr Didier Galmiche

  3. Hydrogen Production and Dispensing Facility Opens at W. Va. Airport

    Broader source: Energy.gov [DOE]

    A hydrogen production and dispensing station constructed and operated with support from the Office of Fossil Energy's National Energy Technology Laboratory was officially opened Monday at the Yeager Airport in Charleston, W.Va.

  4. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    the energy storage capacity. Since 3D silicon morphologiesenergy storage device on the substrate area surrounding MEMS vibration energy harvesters that were microfabricated onto a siliconsilicon die. (b-d) The dispenser printer deposits a multilayer printed energy storage

  5. High Performance Dispenser Printed Thermoelectric Generators

    E-Print Network [OSTI]

    Madan, Deepa

    2013-01-01

    use of TEGs to generate useful energy requires examination.use of TEGs to generate useful energy requires examinationuse of TEGs to generate useful energy requires examination.

  6. Methods and systems for integrating fluid dispensing technology with stereolithography

    DOE Patents [OSTI]

    Medina, Francisco (El Paso, TX); Wicker, Ryan (El Paso, TX); Palmer, Jeremy A. (Albuquerque, NM); Davis, Don W. (Albuquerque, NM); Chavez, Bart D. (Albuquerque, NM); Gallegos, Phillip L. (Albuquerque, NM)

    2010-02-09

    An integrated system and method of integrating fluid dispensing technologies (e.g., direct-write (DW)) with rapid prototyping (RP) technologies (e.g., stereolithography (SL)) without part registration comprising: an SL apparatus and a fluid dispensing apparatus further comprising a translation mechanism adapted to translate the fluid dispensing apparatus along the Z-, Y- and Z-axes. The fluid dispensing apparatus comprises: a pressurized fluid container; a valve mechanism adapted to control the flow of fluid from the pressurized fluid container; and a dispensing nozzle adapted to deposit the fluid in a desired location. To aid in calibration, the integrated system includes a laser sensor and a mechanical switch. The method further comprises building a second part layer on top of the fluid deposits and optionally accommodating multi-layered circuitry by incorporating a connector trace. Thus, the present invention is capable of efficiently building single and multi-material SL fabricated parts embedded with complex three-dimensional circuitry using DW.

  7. Hydrogen, CNG, and HCNG Dispenser System Prototype Report

    SciTech Connect (OSTI)

    James Francfort

    2005-02-01

    The U.S. Department of Energys Advanced Vehicle Testing Activity is currently testing a prototype gaseous fuel dispenser developed by the Electric Transportation Engineering Corporation (ETEC). The dispenser (Figure 1) delivers three types of fuels: 100% hydrogen, 100% compressed natural gas (CNG), and blends of hydrogen and CNG (HCNG) using two independent single nozzles (Figure 2). The nozzle for the 100% hydrogen dispensing is rated at 5,000 psig and used solely for 100% hydrogen fuel. The second nozzle is rated at 3,600 psig and is used for both CNG and HCNG fuels. This nozzle connects to both a CNG supply line and a hydrogen supply line and blends the hydrogen and CNG to supply HCNG levels of 15, 20, 30, and 50% (by volume).

  8. A biomedical device business plan for Medicraften Devices Inc. to develop a fluid medication dispenser

    E-Print Network [OSTI]

    Louison, Charles Davidson

    2006-01-01

    This thesis surrounds an analysis to understand what it would take for a company to successfully launch a prescription fluid dispensing device. This device would in theory be able to dispense medication at any time daily ...

  9. Accurate dispensing of volatile reagents on demand for chemical reactions in EWOD chips{

    E-Print Network [OSTI]

    Accurate dispensing of volatile reagents on demand for chemical reactions in EWOD chips{ Huijiang the use of a filler liquid (e.g., oil). These properties pose challenges for delivering controlled volumes are introduced to the chip, independent of time delays between dispensing operations. On-demand dispensing

  10. Ethanol Distribution, Dispensing, and Use: Analysis of a Portion of the Biomass-to-Biofuels Supply Chain Using System Dynamics

    SciTech Connect (OSTI)

    Vimmerstedt, L. J.; Bush, B.; Peterson, S.

    2012-05-01

    The Energy Independence and Security Act of 2007 targets use of 36 billion gallons of biofuels per year by 2022. Achieving this may require substantial changes to current transportation fuel systems for distribution, dispensing, and use in vehicles. The U.S. Department of Energy and the National Renewable Energy Laboratory designed a system dynamics approach to help focus government action by determining what supply chain changes would have the greatest potential to accelerate biofuels deployment. The National Renewable Energy Laboratory developed the Biomass Scenario Model, a system dynamics model which represents the primary system effects and dependencies in the biomass-to-biofuels supply chain. The model provides a framework for developing scenarios and conducting biofuels policy analysis. This paper focuses on the downstream portion of the supply chain-represented in the distribution logistics, dispensing station, and fuel utilization, and vehicle modules of the Biomass Scenario Model. This model initially focused on ethanol, but has since been expanded to include other biofuels. Some portions of this system are represented dynamically with major interactions and feedbacks, especially those related to a dispensing station owner's decision whether to offer ethanol fuel and a consumer's choice whether to purchase that fuel. Other portions of the system are modeled with little or no dynamics; the vehicle choices of consumers are represented as discrete scenarios. This paper explores conditions needed to sustain an ethanol fuel market and identifies implications of these findings for program and policy goals. A large, economically sustainable ethanol fuel market (or other biofuel market) requires low end-user fuel price relative to gasoline and sufficient producer payment, which are difficult to achieve simultaneously. Other requirements (different for ethanol vs. other biofuel markets) include the need for infrastructure for distribution and dispensing and widespread use of high ethanol blends in flexible-fuel vehicles.

  11. Natural gas vehicle fueling station dispenser meter evaluations

    SciTech Connect (OSTI)

    Rowley, P.F.; Kriha, K.; Blazek, C.F. [Inst. of Gas Technology, Chicago, IL (United States)

    1995-12-31

    The Institute of Gas Technology (IGT) has constructed a multi-purpose meter evaluation facility capable of testing metering technologies for high flow rate and high pressure NGV dispenser applications. The objective of IGT`s meter evaluation program, sponsored by IGT`s Sustaining Membership Program and the Gas Research Institute, is to assist the industry in evaluating the performance and accuracy of currently available flowmeters that are being used or could be applied to CNG gas dispensing. These meters are tested at various flow rates and pressures to determine their performance under NGV fueling station operating conditions and to identify the performance characteristics and limitations for each meter. The metering technologies which are being evaluated under this program include Coriolis meter, sonic nozzle meter, and turbine meter designs.

  12. Semantic label sharing for learning with many categories

    E-Print Network [OSTI]

    Fergus, Rob

    In an object recognition scenario with tens of thousands of categories, even a small number of labels per category leads to a very large number of total labels required. We propose a simple method of label sharing between ...

  13. Method and apparatus for producing drops using a drop-on-demand dispenser

    DOE Patents [OSTI]

    Chen, Alvin U. (West Lafayette, IN); Basaran, Osman A. (West Lafayette, IN)

    2003-01-01

    A method and apparatus for dispensing fluid from a drop-on-demand (DOD) fluid dispenser. The method involves withdrawing fluid in the dispenser for a first duration of time, followed by a second duration of time during which the fluid is propelled toward the orifice of the dispenser. Following the period during which the fluid is propelled, there is a second withdrawing of the fluid into the dispenser. The duration of the propelling period is shorter than the duration of either the first withdrawing or the second withdrawing. The propelling of the fluid results in the extension of a small tongue of fluid from the meniscus of the fluid. The second withdrawing of the fluid results in a retraction of the meniscus into the passageway such that only the small tongue of fluid separates and is ejected from the dispenser.

  14. NREL UL E15 Fuel Dispensing Infrastructure Intermediate Blends Performance Testing (Presentation)

    SciTech Connect (OSTI)

    Moriarty, K.; Clark, W.

    2011-02-01

    Presentation provides an overview of NREL's project to determine compatibility and safe performance of installed fuel dispensing infrastructure with E15.

  15. Detailed Tuning of Structure and Intramolecular Communication Are Dispensable for Processive Motion of Myosin VI

    E-Print Network [OSTI]

    Spudich, James A.

    Detailed Tuning of Structure and Intramolecular Communication Are Dispensable for Processive Motion and intramolecular communication are dispensable for processive motion, and further show theoretically that one. The properties of the lever arm and tail structure of myosin VI, and of other molecular motors, have been

  16. NIST Handbook 112 (2015) EPO No. 22 Retail Motor-Fuel Dispensers Blended Products

    E-Print Network [OSTI]

    2015-01-01

    NIST Handbook 112 (2015) EPO No. 22 Retail Motor-Fuel Dispensers Blended Products RMFD - Blenders (Rev 09/14) DRAFT Page 1 of 12 2015 NIST EPO No. 22 Examination Procedure Outline for Retail Motor-Fuel, and consoles. For non-blending single, dual, and multi-product dispensers, see EPO No. 21. Nonretroactive

  17. NIST Handbook 112 (2015) EPO No. 21 Retail Motor-Fuel Dispensers Single, Dual, and Multi-Product (Except Blenders)

    E-Print Network [OSTI]

    2015-01-01

    NIST Handbook 112 (2015) EPO No. 21 Retail Motor-Fuel Dispensers Single, Dual, and Multi Procedure Outline for Retail Motor-Fuel Dispensers Single, Dual, and Multi-Product (Except Blenders Motor-Fuel Dispensers Single, Dual, and Multi-Product (Except Blenders) Page 2 of 8 RMFD Non

  18. International Comparison of Energy Efficiency Criteria and Test Procedures in Standards and Labeling Programs for Computer Monitors and Commercial Gas Stoves

    E-Print Network [OSTI]

    Khanna, Nina

    2014-01-01

    1.4 Hong Kong Voluntary Energy Label Test Standard forThe Hong Kong Voluntary Energy Efficiency Labeling Schemeon possible Ecodesign and Energy Labelling Requirements for

  19. Controlled free-form fabrication of nanowires by dielectrophoretic dispension of colloids

    E-Print Network [OSTI]

    Daraio, Chiara

    Controlled free-form fabrication of nanowires by dielectrophoretic dispension of colloids Niklas C- electric stepper motor Nanomotion HR4 with a precision of 100 nm . The print head nozzle is manufactured

  20. Motivation Atmospheric Contamination Rejuvenation of a Cesium-Based Dispenser Photocathode

    E-Print Network [OSTI]

    Anlage, Steven

    Motivation Atmospheric Contamination Results Rejuvenation of a Cesium-Based Dispenser Photocathode in Response to Atmospheric Contamination Alexandra Day, Dr. Eric Montgomery, Dr. Kevin Jensen, Blake Riddick, Saara Khan, Scott Eustice Quantum Efficiency Key Conclusions Cs + contaminants higher work function

  1. Dispensing Equipment Testing with Mid-Level Ethanol/Gasoline Test Fluid: Summary Report

    SciTech Connect (OSTI)

    Boyce, K.; Chapin, J. T.

    2010-11-01

    The National Renewable Energy Laboratory's (NREL) Nonpetroleum-Based Fuel Task addresses the hurdles to commercialization of biomass-derived fuels and fuel blends. One such hurdle is the unknown compatibility of new fuels with current infrastructure, such as the equipment used at service stations to dispense fuel into automobiles. The U.S. Department of Energy's (DOE) Vehicle Technology Program and the Biomass Program have engaged in a joint project to evaluate the potential for blending ethanol into gasoline at levels higher than nominal 10 volume percent. This project was established to help DOE and NREL better understand any potentially adverse impacts caused by a lack of knowledge about the compatibility of the dispensing equipment with ethanol blends higher than what the equipment was designed to dispense. This report provides data about the impact of introducing a gasoline with a higher volumetric ethanol content into service station dispensing equipment from a safety and a performance perspective.

  2. Temporal Patterns of Medications Dispensed to Children and Adolescents in a National Insured Population

    E-Print Network [OSTI]

    Olson, Karen L.

    This study aimed to comprehensively describe prevalence and temporal dispensing patterns for medications prescribed to children and adolescents in the United States. Participants were 1.6 million children (49% female) under ...

  3. Navigation Labels and Approval

    Broader source: Energy.gov [DOE]

    EERE has commonly used and approved navigation labels. To maintain consistency in navigation across EERE, the EERE Template Coordinator reviews and approves requests for new navigation labels and...

  4. CNG fueling stations: The dispenser and control benefits of a systems design

    SciTech Connect (OSTI)

    Sullivan, C.D.

    1995-12-31

    A CNG station is composed of many varied pieces of equipment. It is the combined functionality and compatibility of this equipment that distinguishes a CNG fueling system from a CNG fueling station. Components include: dryer, compressor, driver, cooler, blow-down system, priority/sequencing/bypass system; storage; dispenser; and controls. Whether its a system or a station, the objective is the same: to disperse the proper amount of clean dry compressed natural gas into a vehicle quickly. This objective is sometimes overshadowed by the focus on the compressor. It is big, tangible and usually costs the most. The compressor, however is only responsible for compressing the gas, not dispensing it into the vehicle. While there are many different types of compressors on the market, some of which are very good, this paper focuses on the system design and control and its specific effects on the dispensing system.

  5. Labelling and Packaging in Brazil

    E-Print Network [OSTI]

    Cavalcante, Tania M; World Health Organization

    2003-01-01

    Labelling and Packaging in Brazil Tania Maria Cavalcante11 337 8805 Labelling and Packaging in Brazil Introductionchoosing Labelling and Packaging in Brazil about hazards is

  6. Journal of Directed Energy, 3, Fall 2008, 6679 Advances in Cesium Dispenser

    E-Print Network [OSTI]

    Anlage, Steven

    Journal of Directed Energy, 3, Fall 2008, 6679 Advances in Cesium Dispenser Photocathodes those responsive to visible wavelengths (e.g., alkali antimonides), are prone to cesium loss in harsh by gently heating the cathode and allowing cesium to diffuse controllably to the surface through a porous

  7. Significant Impact of Protein Dispensability on the Instantaneous Rate of Protein Evolution

    E-Print Network [OSTI]

    Zhang, Jianzhi

    . High-throughput gene-knockout experiments in model organisms have provided information the dispensability data obtained from a model organism only predicts a short-term rate of protein evolution or unconsciously apply this principle in their daily practice when they use sequence conservation as an indication

  8. Control method for high-pressure hydrogen vehicle fueling station dispensers

    DOE Patents [OSTI]

    Kountz, Kenneth John; Kriha, Kenneth Robert; Liss, William E.

    2006-06-13

    A method for quick filling a vehicle hydrogen storage vessel with hydrogen, the key component of which is an algorithm used to control the fill process, which interacts with the hydrogen dispensing apparatus to determine the vehicle hydrogen storage vessel capacity.

  9. Passive liquid dispensing in capillary-based bio-adhesion Research teams Microfluidics Lab, GRASP (ULg)

    E-Print Network [OSTI]

    Wolper, Pierre

    Passive liquid dispensing in capillary-based bio-adhesion Research teams Microfluidics Lab, GRASP-81 (2010) #12;Coalescence strategies in droplet microfluidic systems Research team Microfluidics Lab, GRASP, mechanics) Droplet microfluidics is a new technology that aims at miniaturizing assays in life science (Lab

  10. Arrt du 31 juillet 2009 relatif au diplme d'Etat d'infirmier TITRE II : DISPENSES DE SCOLARITE

    E-Print Network [OSTI]

    Jeanjean, Louis

    Arrt du 31 juillet 2009 relatif au diplme d'Etat d'infirmier TITRE II : DISPENSES DE SCOLARITE la direction de l'institut de formation en soins infirmiers o ils sont admis dans les dlais

  11. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream

    DOE Patents [OSTI]

    Jacobson, Stephen C.; Ramsey, J. Michael

    2004-09-14

    A microfluidic device for forming and/or dispensing minute volume segments of a material is described. In accordance with one aspect of the present invention, a microfluidic device and method is provided for spatially confining the material in a focusing element. The device is also capable of segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.

  12. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream

    SciTech Connect (OSTI)

    Jacobson, Stephen C [Knoxville, TN; Ramsey, J Michael [Knoxville, TN

    2008-09-09

    A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are provided for spatially confining the material in a focusing element. The device is also adapted for segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.

  13. HAZARDOUS WASTE LABEL DEPAUL UNIVERSITY

    E-Print Network [OSTI]

    Schaefer, Marcus

    HAZARDOUS WASTE LABEL DEPAUL UNIVERSITY ENVIRONMENTAL HEALTH & SAFETY 5-4170 Corrosive Non- Hazardous Ignitable Reactive Toxic Oxidizer Other ( explain ) Generator Building Dept. HAZARDOUS WASTE LABEL DEPAUL UNIVERSITY ENVIRONMENTAL HEALTH & SAFETY 5-4170 HAZARDOUS WASTE LABEL DEPAUL UNIVERSITY

  14. EpiPOD : community vaccination and dispensing model user's guide.

    SciTech Connect (OSTI)

    Berry, M.; Samsa, M.; Walsh, D.; Decision and Information Sciences

    2009-01-09

    EpiPOD is a modeling system that enables local, regional, and county health departments to evaluate and refine their plans for mass distribution of antiviral and antibiotic medications and vaccines. An intuitive interface requires users to input as few or as many plan specifics as are available in order to simulate a mass treatment campaign. Behind the input interface, a system dynamics model simulates pharmaceutical supply logistics, hospital and first-responder personnel treatment, population arrival dynamics and treatment, and disease spread. When the simulation is complete, users have estimates of the number of illnesses in the population at large, the number of ill persons seeking treatment, and queuing and delays within the mass treatment system--all metrics by which the plan can be judged.

  15. Capacitive label reader

    DOE Patents [OSTI]

    Arlowe, H.D.

    1983-07-15

    A capacitive label reader includes an outer ring transmitting portion, an inner ring transmitting portion, and a plurality of insulated receiving portions. A label is the mirror-image of the reader except that identifying portions corresponding to the receiving portions are insulated from only one of two coupling elements. Positive and negative pulses applied, respectively, to the two transmitting rings biased a CMOS shift register positively to either a 1 or 0 condition. The output of the CMOS may be read as an indication of the label.

  16. Cytomegalovirus pp65 limits dissemination but is dispensable for persistence

    SciTech Connect (OSTI)

    Malouli, Daniel; Hansen, Scott G.; Nakayasu, Ernesto S.; Marshall, Emily E.; Hughes, Colette M.; Ventura, Abigail B.; Gilbride, Roxanne M.; Lewis, Matthew S.; Xu, Guangwu; Kreklywich, Craig N.; Whizin, Nathan; Fischer, Miranda; Legasse, Alfred W.; Viswanathan, Kasinath; Siess, Don; Camp, David G.; Axthelm, Michael K.; Kahl, Christoph; DeFilippis, Victor R.; Smith, Richard D.; Streblow, Daniel N.; Picker, Louis J.; Fruh, Klaus

    2014-05-01

    The tegument phosphoprotein pp65 (UL83) is the most abundant virion protein in human cytomegalovirus (HCMV). Since pp65 is immunodominant in persistently infected individuals, subunit vaccines against HCMV often include pp65 as T cell stimulatory component. Although HCMV pp65 is non-essential for viral growth in vitro it is thought to have an important role in primary and persistent infection since pp65 displays multiple immunomodulatory functions. To determine whether pp65 is required for infection and to evaluate its role in natural and vaccination-induced immunity we generated a rhesus CMV lacking both homologues, pp65a (Rh111) and pp65b (Rh112). Lack of pp65 resulted in a slight growth defect in vitro and an increase of defective particle formation. However, most pp65-deleted virions in the supernatant were phenotypically normal and proteomics analysis revealed that the ratios of the remaining viral proteins were largely unchanged. RhCMV ?pp65ab was able to persistently infect CMV-negative rhesus macaques (RM) and to super-infect RM previously infected with CMV. To determine whether T cells against pp65 are essential for protection against CMV, we challenged ?pp65ab-infected animals with RhCMV ?US2-11, a viral recombinant that lacks inhibitors of MHC-I antigen presentation and is thus unable to overcome CMV-specific T cell immunity. Despite a complete lack of pp65-specific T cells, ?pp65ab protected against ?US2-11 challenge suggesting that pp65-specific T cells are not essential for T cell immunity against CMV. Using the same approach we further demonstrate that pp65b-specific T cells, induced by heterologous prime/boost vaccination, are not sufficient to protect against ?US2-11 challenge. Our data provides a new approach to test the efficacy of subunit vaccine candidates and suggest that pp65 vaccines are insufficient to induce a T cell response that recapitulates the protective effect of natural infection.

  17. Evalutation and network of ec-decision support systems in the field of hydrological dispension models and of aquatic radioecological research Assessment of environmental models anf software

    E-Print Network [OSTI]

    Monte, L; Hofman, Dimitry

    2005-01-01

    Evalutation and network of ec-decision support systems in the field of hydrological dispension models and of aquatic radioecological research

  18. System for Dispensing a Precise Amount of Fluid (Patent) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail. (Conference)Feedback System inStatusandArticle)SystemSystem for Dispensing a Precise

  19. System for Dispensing a Precise Amount of Fluid (Patent) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail. (Conference)Feedback System inStatusandArticle)SystemSystem for Dispensing a

  20. Dispensing Equipment Testing With Mid-Level Ethanol/Gasoline Test Fluid

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department8,Department of Energy2EM's CleanupPower » Dispensing

  1. Automatic Routing Using Multiple Prefix Labels

    E-Print Network [OSTI]

    Garcia-Luna-Aceves, J.J.; Ghosh, R.

    2012-01-01

    Automatic Routing Using Multiple Prefix Labels Rumi GhoshWe present Multi-label Automatic Routing (MAR), the firstthe routing is automatic based on the positional labels of

  2. IP SwitchingIP Switching and Label Switchingand Label Switching

    E-Print Network [OSTI]

    Jain, Raj

    Raj Jain 1 IP SwitchingIP Switching and Label Switchingand Label Switching Raj Jain Professor Switching vs routing q IP Switching (Ipsilon) q Tag Switching (CISCO) q Multi-protocol label switching a tag. Exit router strips it off. H R R R H H HUntagged Packet Tagged packet #12;Raj Jain 9 Tag

  3. Method and apparatus for dispensing small quantities of mercury from evacuated and sealed glass capsules

    DOE Patents [OSTI]

    Grossman, M.W.; George, W.A.; Pai, R.Y.

    1985-08-13

    A technique is disclosed for opening an evacuated and sealed glass capsule containing a material that is to be dispensed which has a relatively high vapor pressure such as mercury. The capsule is typically disposed in a discharge tube envelope. The technique involves the use of a first light source imaged along the capsule and a second light source imaged across the capsule substantially transversely to the imaging of the first light source. Means are provided for constraining a segment of the capsule along its length with the constraining means being positioned to correspond with the imaging of the second light source. These light sources are preferably incandescent projection lamps. The constraining means is preferably a multiple looped wire support. 6 figs.

  4. Hydrogen Station Compression, Storage, and Dispensing Technical Status and Costs: Systems Integration

    SciTech Connect (OSTI)

    Parks, G.; Boyd, R.; Cornish, J.; Remick, R.

    2014-05-01

    At the request of the U.S. Department of Energy Fuel Cell Technologies Office (FCTO), the National Renewable Energy Laboratory commissioned an independent review of hydrogen compression, storage, and dispensing (CSD) for pipeline delivery of hydrogen and forecourt hydrogen production. The panel was asked to address the (1) cost calculation methodology, (2) current cost/technical status, (3) feasibility of achieving the FCTO's 2020 CSD levelized cost targets, and to (4) suggest research areas that will help the FCTO reach its targets. As the panel neared the completion of these tasks, it was also asked to evaluate CSD costs for the delivery of hydrogen by high-pressure tube trailer. This report details these findings.

  5. Microfluidic Radiometal Labeling Systems for Biomolecules

    SciTech Connect (OSTI)

    Reichert, D E; Kenis, P J. A.

    2011-12-29

    In a typical labeling procedure with radiometals, such as Cu-64 and Ga-68; a very large (~ 100-fold) excess of the non-radioactive reactant (precursor) is used to promote rapid and efficient incorporation of the radioisotope into the PET imaging agent. In order to achieve high specific activities, careful control of reaction conditions and extensive chromatographic purifications are required in order to separate the labeled compounds from the cold precursors. Here we propose a microfluidic approach to overcome these problems, and achieve high specific activities in a more convenient, semi-automated fashion and faster time frame. Microfluidic reactors, consisting of a network of micron-sized channels (typical dimensions in the range 10 â?? 300 ?¼m), filters, separation columns, electrodes and reaction loops/chambers etched onto a solid substrate, are now emerging as an extremely useful technology for the intensification and miniaturization of chemical processes. The ability to manipulate, process and analyze reagent concentrations and reaction interfaces in both space and time within the channel network of a microreactor provides the fine level of reaction control that is desirable in PET radiochemistry practice. These factors can bring radiometal labeling, specifically the preparation of radio-labeled biomolecules such as antibodies, much closer to their theoretical maximum specific activities.

  6. Dispensing thin liquid films using dielectrophoresis R. Ahmed,1 T. N. Tombs,2 T. B. Jones,1 and P. Leas2

    E-Print Network [OSTI]

    Jones, Thomas B.

    system using liquid dielectrophoresis to dispense thin films of viscous, insulating liquid onto rolls in evaporated metal on an insulating substrate. A thin coating of a low-surface energy material covering

  7. To label or not to label, the GMO food paradox Is labeling of foods containing GMOs a consumer right? Or does labeling of GMO

    E-Print Network [OSTI]

    Ciocan-Fontanine, Ionut

    To label or not to label, the GMO food paradox Is labeling of foods containing GMOs a consumer right? Or does labeling of GMO foods create a false warning? Are voluntary initiatives sufficient and government agencies? As States and the nation grapple with the GMO labeling paradox, the Finding Common

  8. Semi-automated lab-on-a-chip for dispensing GA-68 radiotracers

    SciTech Connect (OSTI)

    Weinberg, Irving

    2014-03-12

    We solved a technical problem that is hindering American progress in molecular medicine, and restricting US citizens from receiving optimal diagnostic care. Specifically, the project deals with a mother/daughter generator of positron-emitting radiotracers (Ge-68/Ga-68). These generator systems are approved in Europe but cannot be used in the USA, because of safety issues related to possible breakthrough of long-lived Ge-68 (mother) atoms. Europeans have demonstrated abilities of Ga-68-labeled radiotracers to image cancer foci with high sensitivity and specificity, and to use such methods to effectively plan therapy.The USA Food and Drug Administration (FDA) and Nuclear Regulatory Commission (NRC) have taken the position that every patient administration of Ga-68 should be preceded by an assay demonstrated that Ge-68 breakthrough is within acceptable limits. Breakthrough of parent elements is a sensitive subject at the FDA, as evidenced by the recent recall of Rb-82 generators due to inadvertent administrations of Sr-82. Commercially, there is no acceptable rapid method for assaying breakthrough of Ge-68 prior to each human administration. The gamma emissions of daughter Ga-68 have higher energies than the parent Ge-68, so that the shielding assays typically employed for Mo-99/Tc-99m generators cannot be applied to Ga-68 generators. The half-life of Ga-68 is 68 minutes, so that the standard 10-half-life delay (used to assess breakthrough in Sr-82/Rb-82 generators) cannot be applied to Ga-68 generators. As a result of the aforementioned regulatory requirements, Ga-68 generators are sold in the USA for animal use only.The American clinical communitys inability to utilize Ga-68 generators impairs abilities to treat patients domestically, and puts the USA at a disadvantage in developing exportable products. The proposed DOE project aimed to take advantage of recent technological advances developed for lab-on-a-chip (LOC) applications. Based on our experiences constructing such devices, the proposed microfluidics-based approach could provide cost-effective validation of breakthrough compliance in minutes.

  9. Thailand: Country Report on Labelling and Packaging

    E-Print Network [OSTI]

    Chitanondh, Hatai; World Health Organization

    2003-01-01

    implemented because packaging and labelling is a section ofReport on Labelling and Packaging Hatai Chitanondh M.D. , F.Report on Labelling and Packaging Introduction From 1981 to

  10. Thailand: Country Report on Labelling and Packaging

    E-Print Network [OSTI]

    Chitanondh, Hatai; World Health Organization

    2003-01-01

    interviews. Conclusion Package labelling is a vital measureLabelling Committee mandated a seventh health warning on cigarette packages,Labelling and Packaging In Thailand, there has been no scientific study of the impact of cigarette package

  11. Background Knowledge, Category Labels, and Similarity Judgment

    E-Print Network [OSTI]

    Yu, Na-Yung

    2011-10-21

    Labels are one source of our judgments. By assigning labels to objects, we not only create references but we also group prior and current experiences together. The goal of this research is to investigate how labels influence ...

  12. Off-label indications for imiquimod

    E-Print Network [OSTI]

    Ganjian, Shahrouz; Ourian, Ariel J; Shamtoub, GabrEal; Wu, Jashin J; Murase, Jenny E

    2009-01-01

    Off-label indications for imiquimod Shahrouz Ganjian 1 ,potential candidate for off-label use in over 60 conditionspotential candidate for off-label use in over 60 conditions

  13. Oxygen transport in the internal xenon plasma of a dispenser hollow cathode

    SciTech Connect (OSTI)

    Capece, Angela M. Shepherd, Joseph E.; Polk, James E.; Mikellides, Ioannis G.

    2014-04-21

    Reactive gases such as oxygen and water vapor modify the surface morphology of BaO dispenser cathodes and degrade the electron emission properties. For vacuum cathodes operating at fixed temperature, the emission current drops rapidly when oxygen adsorbs on top of the low work function surface. Previous experiments have shown that plasma cathodes are more resistant to oxygen poisoning and can operate with O{sub 2} partial pressures one to two orders of magnitude higher than vacuum cathodes before the onset of poisoning occurs. Plasma cathodes used for electric thrusters are typically operated with xenon; however, gas phase barium, oxygen, and tungsten species may be found in small concentrations. The densities of these minor species are small compared with the plasma density, and thus, their presence in the discharge does not significantly alter the xenon plasma parameters. It is important, however, to consider the transport of these minor species as they may deposit on the emitter surface and affect the electron emission properties. In this work, we present the results of a material transport model used to predict oxygen fluxes to the cathode surface by solving the species conservation equations in a cathode with a 2.25?mm diameter orifice operated at a discharge current of 15?A, a Xe flow rate of 3.7 sccm, and 100?ppm of O{sub 2}. The dominant ionization process for O{sub 2} is resonant charge exchange with xenon ions. Ba is effectively recycled in the plasma; however, BaO and O{sub 2} are not. The model shows that the oxygen flux to the surface is not diffusion-limited; therefore, the high resistance to oxygen poisoning observed in plasma cathodes likely results from surface processes not considered here.

  14. H2FIRST Hydrogen Contaminant Detector Task: Requirements Document and Market Survey

    SciTech Connect (OSTI)

    Terlip, Danny; Ainscough, Chris; Buttner, William; McWhorter, Scott

    2015-04-20

    The rollout of hydrogen fueling stations, and the fuel cell electric vehicles (FCEV) they support, requires the assurance of high quality hydrogen at the dispensing point. Automotive fuel cells are sensitive to a number of chemicals that can be introduced into the dispensed fuel at multiple points. Quality assurance and quality control methods are employed by the industry to ensure product quality, but they are not completely comprehensive and can fail at various points in the hydrogen pathway from production to dispensing. This reality leaves open the possibility of a station unknowingly dispensing harmful contaminants to a FCEV which, depending on the contaminant, may not be discovered until the FCEV is irreparably damaged. This situation is unacceptable. A hydrogen contaminant detector (HCD), defined as a combination of a gas analyzer and the components necessary for fuel stream integration, installed at hydrogen stations is one method for preventing poor quality gas from reaching an FCEV. This document identifies the characteristics required of such a device by industry and compares those requirements with the current state of commercially available gas analysis technology.

  15. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards and Labeling Programs for Clothes Washers, Water Dispensers, Vending Machines and CFLs

    E-Print Network [OSTI]

    Fridley, David

    2010-01-01

    wash performance, water extraction, etc. ) during whichand spin extraction processes as well as heating water is

  16. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards and Labeling Programs for Clothes Washers, Water Dispensers, Vending Machines and CFLs

    E-Print Network [OSTI]

    Fridley, David

    2010-01-01

    content test in which water and energy consumption areconsumption, the hot water energy consumption and the energyenergy consumption, hot water energy consumption and energy

  17. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards and Labeling Programs for Clothes Washers, Water Dispensers, Vending Machines and CFLs

    E-Print Network [OSTI]

    Fridley, David

    2010-01-01

    lumens. The Energy Star program also includes luminous fluxprograms, energy efficiency is defined as initial luminousthe initial 100-hour luminous flux. Besides Energy Star, all

  18. Comparison of Test Procedures and Energy Efficiency Criteria in Selected International Standards and Labeling Programs for Clothes Washers, Water Dispensers, Vending Machines and CFLs

    E-Print Network [OSTI]

    Fridley, David

    2010-01-01

    in the Energy Star, Australia, Brazil and EU programs butBesides Energy Star, all China, Australia, Brazil and EUBrazil, South Korea and Australia also have mandatory energy

  19. Synthesis Of Labeled Metabolites

    DOE Patents [OSTI]

    Martinez, Rodolfo A. (Santa Fe, NM); Silks, III, Louis A. (Los Alamos, NM); Unkefer, Clifford J. (Los Alamos, NM); Atcher, Robert (White Rock, NM)

    2004-03-23

    The present invention is directed to labeled compounds, for example, isotopically enriched mustard gas metabolites including: [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1,1'-sulfonylbis[2-(methylthio); [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1-[[2-(methylsulfinyl)ethyl]sulfonyl]-2-(methylthio); [1,1',2,2'-.sup.13 C.sub.4 ]ethane, 1,1'-sulfonylbis[2-(methylsulfinyl)]; and, 2,2'-sulfinylbis([1,2-.sup.13 C.sub.2 ]ethanol of the general formula ##STR1## where Q.sup.1 is selected from the group consisting of sulfide (--S--), sulfone (--S(O)--), sulfoxide (--S(O.sub.2)--) and oxide (--O--), at least one C* is .sup.13 C, X is selected from the group consisting of hydrogen and deuterium, and Z is selected from the group consisting of hydroxide (--OH), and --Q.sup.2 --R where Q.sup.2 is selected from the group consisting of sulfide (--S--), sulfone(--S(O)--), sulfoxide (--S(O.sub.2)--) and oxide (--O--), and R is selected from the group consisting of hydrogen, a C.sub.1 to C.sub.4 lower alkyl, and amino acid moieties, with the proviso that when Z is a hydroxide and Q.sup.1 is a sulfide, then at least one X is deuterium.

  20. DOE Challenge Home Label Methodology

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the core value messages of the DOE Challenge Home The model for the label compares building science and quality measures of a DOE Challenge Home in six major categories to both...

  1. Care Labels and Your Clothes

    E-Print Network [OSTI]

    Brown, Pamela J.

    1998-05-12

    This publication explains the care symbols that must appear on all clothing. These labels indicate proper care methods--washing, drying, bleaching, ironing and dry cleaning. If clothes are damaged when specified care methods are used, consumers can...

  2. BUDVYTIS et al.: LABEL PROPAGATION 1 Label propagation in complex video

    E-Print Network [OSTI]

    Kim, Tae-Kyun

    Propagation (PGP) Proposed Hybrid Model (PHM) Occlusion-aware labelling (Classifier injection off ) ProlongedBUDVYTIS et al.: LABEL PROPAGATION 1 Label propagation in complex video sequences using semi graphical model for label propagation in lengthy and complex video sequences. Given hand-labelled start

  3. Translocation by the RecB Motor Is an Absolute Requirement for -Recognition and RecA Protein Loading by

    E-Print Network [OSTI]

    Kowalczykowski, Stephen C.

    the RecD subunit has a dispensable motor activity but an indispensable regu- latory function. RecTranslocation by the RecB Motor Is an Absolute Requirement for -Recognition and RecA Protein. The enzyme is driven by two motor subunits, RecB and RecD, trans- locating on opposite single

  4. Positron emitter labeled enzyme inhibitors

    DOE Patents [OSTI]

    Fowler, Joanna S. (Bellport, NY); MacGregor, Robert R. (Sag Harbor, NY); Wolf, Alfred P. (Setauket, NY); Langstrom, Bengt (Upsala, SE)

    1990-01-01

    This invention involves a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide inactivators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography.

  5. Positron emitter labeled enzyme inhibitors

    DOE Patents [OSTI]

    Fowler, J.S.; MacGregor, R.R.; Wolf, A.P.

    1987-05-22

    This invention involved a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymatic catalysis. Two such suicide in activators for monoamine oxidase have been labeled with carbon-11 and used to map the enzyme subtypes in the living human and animal body using PET. By using positron emission tomography to image the distribution of radioactivity produced by the body penetrating radiation emitted by carbon-11, a map of functionally active monoamine oxidase activity is obtained. Clorgyline and L-deprenyl are suicide enzyme inhibitors and irreversibly inhibit monoamine oxidase. When these inhibitors are labeled with carbon-11 they provide selective probes for monoamine oxidase localization and reactivity in vivo using positron emission tomography. 2 figs.

  6. Explore the Genetic Frontier: Labeling Foods Derived from Biotechnology

    E-Print Network [OSTI]

    Vestal, Andy; Hawkins, Carole

    2002-10-19

    Today's food labels provide consumers with nutrition information. This publication discusses the content of labels on foods derived from biotechnology and the agencies that regulate such labeling....

  7. CD Label and Package Templates

    Broader source: Energy.gov [DOE]

    The Office of Energy Efficiency and Renewable Energy (EERE) has developed templates for CD labels and CD packages. These can be used for all EERE products. Both templates are available as EPS files, which can be downloaded and edited in a graphics package like Adobe Illustrator.

  8. Diagrams of affine permutations and their labellings

    E-Print Network [OSTI]

    Yun, Taedong

    2013-01-01

    We study affine permutation diagrams and their labellings with positive integers. Balanced labellings of a Rothe diagram of a finite permutation were defined by Fomin- Greene-Reiner-Shimozono, and we extend this notion to ...

  9. Controlled Dispensing and Mixing of Pico- to Nanoliter Volumes Using On-Demand Droplet-Based Microfluidics

    SciTech Connect (OSTI)

    Sun, Xuefei; Tang, Keqi; Smith, Richard D.; Kelly, Ryan T.

    2013-07-08

    We present an integrated droplet-on-demand microfluidic platform for dispensing, mixing, incubating, extracting and analyzing by mass spectrometry pico- to nanoliter sized droplets. Droplet generation is accomplished using computer-controlled pneumatic valves. Controlled actuation of valves for different aqueous streams enables controlled dosing and rapid mixing of reagents within droplets in the droplet generation area or in a region with widening channel cross-section. Following incubation, which takes place while droplets travel in the oil stream, the droplet contents are extracted to an aqueous channel for subsequent ionization at an integrated nanoelectrospray emitter. As an initial demonstration of the platform, rapid enzymatic digestions of a model protein are performed in droplets and detected on-line by nanoelectrospray ionization mass spectrometry.

  10. Method and apparatus for dispensing compressed natural gas and liquified natural gas to natural gas powered vehicles

    DOE Patents [OSTI]

    Bingham, Dennis A.; Clark, Michael L.; Wilding, Bruce M.; Palmer, Gary L.

    2005-05-31

    A fueling facility and method for dispensing liquid natural gas (LNG), compressed natural gas (CNG) or both on-demand. The fueling facility may include a source of LNG, such as cryogenic storage vessel. A low volume high pressure pump is coupled to the source of LNG to produce a stream of pressurized LNG. The stream of pressurized LNG may be selectively directed through an LNG flow path or to a CNG flow path which includes a vaporizer configured to produce CNG from the pressurized LNG. A portion of the CNG may be drawn from the CNG flow path and introduced into the CNG flow path to control the temperature of LNG flowing therethrough. Similarly, a portion of the LNG may be drawn from the LNG flow path and introduced into the CNG flow path to control the temperature of CNG flowing therethrough.

  11. DOE Requires Manufacturer and Labeler to Cease Sale of Incandescent

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department ofRefrigeratorsDepartmentEP9425

  12. Hanford Site Beryllium Posting and Labeling Requirements Procedure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journalvivo Low-Dose Low34OctoberK West Basincocooningpump Tags2-003

  13. Truth-values as labels: a general recipe for labelled deduction

    E-Print Network [OSTI]

    Lisboa, Universidade Tcnica de

    Truth-values as labels: a general recipe for labelled deduction C. Sernadas1 L. Vigan`o2 J. Rasga1@inf.ethz.ch www.infsec.ethz.ch/~vigano Abstract We introduce a general recipe for presenting non-classical logics in a modular and uniform way as labelled deduction systems. Our recipe is based on a labelling mechanism where

  14. Estimating Labels from Label Proportions Novi Quadrianto novi.quad@gmail.com

    E-Print Network [OSTI]

    Caetano, Tiberio

    Estimating Labels from Label Proportions Novi Quadrianto novi.quad@gmail.com Alex J. Smola alex proportions, predict the labels of an- other set of observations, also with known label proportions) are available. The mixing proportions can be reliably estimated using random assignment to control and treatment

  15. Planar digital nanoliter dispensing system based on thermocapillary actuation Anton A. Darhuber,*a

    E-Print Network [OSTI]

    Troian, Sandra M.

    ,6 dielectrophoresis,7,8 surface-acoustic waves9 and thermocapillary propulsion.10 With each of these techniques controlled. Experimental results for the power required to extract a filament and to divide it into two

  16. On distinguishing progressively increasing response requirements for reinforcement.

    E-Print Network [OSTI]

    Jarmolowicz, David P.; Lattal, K. A.

    2010-03-01

    Several different arrangements have been described for increasing the response requirements for reinforcement using the label progressive-ratio schedule. Under the original progressive-ratio schedule, the response requirement is increased after each...

  17. Rational design and directed evolution of probe ligases for site-specific protein labeling and live-cell imaging

    E-Print Network [OSTI]

    White, Katharine Alice

    2012-01-01

    Chemical fluorophores have superior photophysical properties to fluorescent proteins and are much smaller. However, in order to use these probes for live-cell protein imaging, highly specific labeling methods are required. ...

  18. Competing Environmental Labels DRAFT: DO NOT CIRCULATE

    E-Print Network [OSTI]

    Lyon, Thomas P.

    to dolphin-safe tuna (Reinhardt 2000, pp. 31-34) or the pulp and paper industry's "Totally Chlorine Free with the standard. Alternatively, industry can create its own standard and label. We compare the stringency such as ecolabeling. In some cases, industry takes the lead in developing labels, as in the case of Starkist's move

  19. Labeled nucleotide phosphate (NP) probes

    DOE Patents [OSTI]

    Korlach, Jonas (Ithaca, NY); Webb, Watt W. (Ithaca, NY); Levene, Michael (Ithaca, NY); Turner, Stephen (Ithaca, NY); Craighead, Harold G. (Ithaca, NY); Foquet, Mathieu (Ithaca, NY)

    2009-02-03

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  20. Integrated Nanoplasmonic Optical Microfluidics for Label-free Bioassays

    E-Print Network [OSTI]

    Wu, Yir-shyuan

    2009-01-01

    42) Bruus, H. Theoretical microfluidics 2008. C HAPTER 3: CNanoplasmonic Optical Microfluidics for Label-free BioassaysNanoplasmonic Optical Microfluidics for Label-free Bioassays

  1. Nanomaterial Labels in Electrochemical Immunosensors and Immunoassays

    SciTech Connect (OSTI)

    Liu, Guodong; Lin, Yuehe

    2007-12-15

    This article reviews recent advances in nanomaterial labels in electrochemical immunosensors and immunoassays. Various nanomaterial labels are discussed, including colloidal gold/silver, semiconductor nanoparticles, and markers loaded nanocarriers (carbon nanotubes, apoferritin, silica nanoparticles, and liposome beads). The enormous signal enhancement associated with the use of nanomaterial labels and with the formation of nanomaterialantibody-antigen assemblies provides the basis for ultrasensitive electrochemical detection of disease-related protein biomarkers, biothreat agents, or infectious agents. In general, all endeavors cited here are geared to achieve one or more of the following goals: signal amplification by several orders of magnitude, lower detection limits, and detecting multiple targets.

  2. Lumens and the Lighting Facts Label

    Broader source: Energy.gov [DOE]

    When you're shopping for lightbulbs, compare lumens and use the Lighting Facts label to be sure you're getting the amount of light, or level of brightness, you want.

  3. Technical development of an electromechanical braille labeler

    E-Print Network [OSTI]

    Calbry-Muzyka, Adelaide S

    2009-01-01

    The work presented in this thesis concerns the development of an electromechanical device that prints labels in braille. For blind and visually impaired people, differentiating between similarly-shaped objects - CDs, ...

  4. DAAL019620001 Image Segmentation and Labeling

    E-Print Network [OSTI]

    Alajaji, Fady

    for contagious phenomena. An initial estimate of the pixel labels is obtained using a Maximum Likelihood (ML sampling proce dure was originally designed to model the development of contagious phenomena. For our

  5. Radionuclide labeled lymphocytes for therapeutic use

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Richards, P.

    1983-05-03

    Lymphocytes labelled with ..beta..-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected radionuclide-oxine complex.

  6. Labeling of Ready-Made Street Dresses.

    E-Print Network [OSTI]

    Drake, Phyllis; Grimes, Mary Anna

    1959-01-01

    CONSIDERED MOST HELPFUL Information Percent of women using Care (dry clean or wash) Washing instructions Fiber content Brand Shrinkage Size Colorfastness Finish Manufacturer's name Miscellaneous Availability of Information or Dresses tag only... No label Both Figure 4. Types of labels on 4,603 dresses in stores. may be made in half sizes or diminutives or have extra length in the waist. Fewer women indicated that shrinkage, color- fastness, size and finish were helpful. The low per- centage...

  7. Laser Etching: A Novel Technology to Label Florida Grapefruit

    E-Print Network [OSTI]

    Burns, Jacqueline K.

    Laser Etching: A Novel Technology to Label Florida Grapefruit Preeti Sood1 , Chris Ference2 , Jan, produce labeling SUMMARY. Laser labeling of fruit and vegetables is an alternative means of labeling produce in which a low-energy carbon dioxide laser beam etches the surface and reveals a contrasting

  8. Spectral Label Fusion Christian Wachinger1,2

    E-Print Network [OSTI]

    Golland, Polina

    off. The segmentation with spectral label fusion, which fuses image and label information, leadsSpectral Label Fusion Christian Wachinger1,2 and Polina Golland1 1 Computer Science and Artificial a new segmentation approach that combines the strengths of label fusion and spectral clustering

  9. A Simple and Efficient Algorithm for High-Quality Line Labeling

    E-Print Network [OSTI]

    Utrecht, Universiteit

    , namely polygonal chains, such as rivers or streets. Our method is simple and efficient. At the same time requirements: it allows curved labels and runs in O(n2 ) time, where n is the number of points of the polyline the hard constraints. In order to optimize soft constraints, we use one or a combination of several

  10. Probes labelled with energy transfer coupled dyes

    DOE Patents [OSTI]

    Mathies, R.A.; Glazer, A.; Ju, J.

    1997-11-18

    Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.

  11. Probes labelled with energy transfer coupled dyes

    DOE Patents [OSTI]

    Mathies, Richard A. (El Cerrito, CA); Glazer, Alexander (Orinda, CA); Ju, Jingyue (Berkeley, CA)

    1997-01-01

    Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids.

  12. Labelling Heuristics for CSP Application Domains

    E-Print Network [OSTI]

    Rossi, Francesca

    Labelling Heuristics for CSP Application Domains Zeynep K#16;z#16;ltan Computer Science Division an application domain as a family of CSP models, so as to exhibit the generic constraint store for all models store and the domain propagation during search is analysed, so as to infer | before modelling any CSP

  13. Animation Requirements

    Broader source: Energy.gov [DOE]

    Animations include dynamic elements such as interactive images and games. For developing animations, follow these design and coding requirements.

  14. Lumens and the Lighting Facts Label | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lumens and the Lighting Facts Label Lumens and the Lighting Facts Label July 28, 2014 - 7:44pm Addthis An error occurred. Try watching this video on www.youtube.com, or enable...

  15. An introduction to the National Tritium Labeling Facility

    SciTech Connect (OSTI)

    Dorsky, A.M.; Morimoto, H.; Saljoughian, M.; Williams, P.G.; Rapoport, H.

    1988-06-01

    The facilities and projects of the National Tritium Labeling Facility are described. 5 refs., 1 fig., 1 tab.

  16. Automatic Labeling and Segmentation of Vertebrae in CT Images

    E-Print Network [OSTI]

    Freitas, Nando de

    vertebral column. I validate my technique in terms of accuracy of the labeling and segmentation of CT images handled labeling of the vertebral column in arbitrary scans [3, 4]. Klinder et al. build a template (mean(s) Affiliation Address email Abstract Detection, Labeling, and segmentation of the spinal column from CT images

  17. Automatic Labeling for Entity Extraction in Cyber Security

    SciTech Connect (OSTI)

    Bridges, Robert A; Jones, Corinne L; Iannacone, Michael D; Testa, Kelly M; Goodall, John R

    2014-01-01

    Timely analysis of cyber-security information necessitates automated information extraction from unstructured text. While state-of-the-art extraction methods produce extremely accurate results, they require ample training data, which is generally unavailable for specialized applications, such as detecting security related entities; moreover, manual annotation of corpora is very costly and often not a viable solution. In response, we develop a very precise method to automatically label text from several data sources by leveraging related, domain-specific, structured data and provide public access to a corpus annotated with cyber-security entities. Next, we implement a Maximum Entropy Model trained with the average perceptron on a portion of our corpus (~750,000 words) and achieve near perfect precision, recall, and accuracy, with training times under 17 seconds.

  18. Video Requirements

    Broader source: Energy.gov [DOE]

    All EERE videos, including webinar recordings, must meet Section 508's requirements for accessibility. All videos should be hosted on the DOE YouTube channel.

  19. Colloid labelled with radionuclide and method

    DOE Patents [OSTI]

    Atcher, R.W.; Hines, J.J.

    1990-11-13

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints. No Drawings

  20. International Experience in Standards and Labeling Programs for Rice Cookers

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina

    2008-05-01

    China has had an active program on energy efficiency standards for household appliances since the mid-1990s. Rice cooker is among the first to be subject to such mandatory regulation, since it is one of the most prevalent electric appliances in Chinese households. Since first introduced in 1989, the minimum energy efficiency standard for rice cookers has not been revised. Therefore, the potential for energy saving is considerable. Initial analysis from CNIS indicates that potential carbon savings is likely to reach 7.6 million tons of CO2 by the 10th year of the standard implementation. Since September 2007, CNIS has been working with various groups to develop the new standard for rice cookers. With The Energy Foundation's support, LBNL has assisted CNIS in the revision of the minimum energy efficiency standard for rice cookers that is expected to be effective in 2009. Specifically, work has been in the following areas: assistance in developing consumer survey on usage pattern of rice cookers, review of international standards, review of international test procedures, comparison of the international standards and test procedures, and assessment of technical options of reducing energy use. This report particularly summarizes the findings of reviewing international standards and technical options of reducing energy consumption. The report consists of an overview of rice cooker standards and labeling programs and testing procedures in Hong Kong, South Korea, Japan and Thailand, and Japan's case study in developing energy efficiency rice cooker technologies and rice cooker efficiency programs. The results from the analysis can be summarized as the follows: Hong Kong has a Voluntary Energy Efficiency Labeling scheme for electric rice cookers initiated in 2001, with revision implemented in 2007; South Korea has both MEPS and Mandatory Energy Efficiency Label targeting the same category of rice cookers as Hong Kong; Thailand's voluntary endorsement labeling program is similar to Hong Kong in program design but has 5 efficiency grades; Japan's program is distinct in its adoption of the 'Top Runner' approach, in which, the future efficiency standards is set based on the efficiency levels of the most efficient product in the current domestic market. Although the standards are voluntary, penalties can still be evoked if the average efficiency target is not met. Both Hong Kong and South Korea's tests involve pouring water into the inner pot equal to 80% of its rated volume; however, white rice is used as a load for its tests in Hong Kong whereas no rice is used for tests in South Korea. In Japan's case, water level specified by the manufactures is used and milled rice is used as a load only partially in the tests. Moreover, Japan does not conduct heat efficiency test but its energy consumption measurements tests are much more complex, with 4 different tests are conducted to determine the annual average energy consumption. Hong Kong and Thailand both set Minimum Allowable Heat Efficiency for different rated wattages. The energy efficiency requirements are identical except that the minimum heat efficiency in Thailand is 1 percentage point higher for all rated power categories. In South Korea, MEPS and label's energy efficiency grades are determined by the rice cooker's Rated Energy Efficiency for induction, non-induction, pressure, nonpressure rice cookers. Japan's target standard values are set for electromagnetic induction heating products and non-electromagnetic induction heating products by different size of rice cookers. Specific formulas are used by type and size depending on the mass of water evaporation of the rice cookers. Japan has been the leading country in technology development of various types of rice cookers, and developed concrete energy efficiency standards for rice cookers. However, as consumers in Japan emphasize the deliciousness of cooked rice over other factors, many types of models were developed to improve the taste of cooked rice. Nonetheless, the efficiency of electromagnetic induction heating (IH) rice cook

  1. June 11, 2015 Correction to: NIST Handbook 130 (2015), Uniform Laws and Regulations in the Areas of Legal Metrology and

    E-Print Network [OSTI]

    2015-01-01

    that includes the installation of bulk vehicle engine (motor) oil dispensed from a receptacle, dispenser. The label on any vehicle engine (motor) oil container, receptacle, dispenser or storage tank and the invoice. The label on any vehicle engine (motor) oil container, receptacle, dispenser, or storage tank

  2. JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS J Label Compd Radiopharm 2003; 46: 11271140.

    E-Print Network [OSTI]

    Pike, Victor W.

    .8%) to provide a new labeling agent of potential value in radiopharmaceutical development for positron emission-produced [11 C]carbon dioxide or [11 C]methane by known procedures. The first method (route 1) consisted from the end of radionuclide production (ERP). However, co- production of n-butanesulfonyl chloride

  3. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, P.; Mausner, L.F.; Prach, T.F.

    1985-04-29

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  4. China Refrigerator Information Label: Specification Development and Potential Impact

    E-Print Network [OSTI]

    Fridley, David

    2008-01-01

    Urban Refrigerator Stocks, 1990-2006 5 Figure 3 China's Energy Information Label for Refrigerators.. 6 Figure 4 China's Voluntary Energy Efficiency

  5. Enhancing the Sensitivity of Label-free Silicon Photonic Biosensors...

    Office of Scientific and Technical Information (OSTI)

    Enhancing the Sensitivity of Label-free Silicon Photonic Biosensors through Increased Probe Molecule Density Citation Details In-Document Search Title: Enhancing the Sensitivity of...

  6. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, P.; Mausner, L.F.; Prach, T.F.

    1987-11-17

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  7. Beryllium-7 labeled carbon particles and method of making

    DOE Patents [OSTI]

    Richards, Powell (New Bern, NC); Mausner, Leonard F. (Stony Brook, NY); Prach, Thomas F. (Port Jefferson, NY)

    1987-01-01

    Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.

  8. Interpreting a Fish Food Package Label1 Frank Chapman and Richard Miles2

    E-Print Network [OSTI]

    Hill, Jeffrey E.

    FA159 Interpreting a Fish Food Package Label1 Frank Chapman and Richard Miles2 1. This document, and Cosmetic Act, FFDCA). These commodities must also be properly identified and labeled (Nutrition Labeling is to disclose a label or feed tag. The label then serves as an ad- vertising icon and legal document. A food

  9. Pulse and chase labeling with [35S]-Methionine Lucho Fuentealba 2008

    E-Print Network [OSTI]

    De Robertis, Eddy M.

    Pulse and chase labeling with [35S]-Methionine Lucho Fuentealba 2008 This protocol is prepared in Fibronectin 20 g/ml and use them at a confluence of 70-80% - Pulse-labeling medium: Met- Cys-free DMEM (Gibco-warmed (37C) pulse-labeling medium Labeling of cells - Wash cells twice with 1 ml of pulse-labeling medium

  10. Matrix Completion for Multi-label Image Classification

    E-Print Network [OSTI]

    Instituto de Sistemas e Robotica

    Matrix Completion for Multi-label Image Classification Ricardo S. Cabral, Fernando De la Torre and browse digital images via semantic keywords. This paper for- mulates image categorization as a multi-label classification problem using recent advances in matrix completion. Under this setting, classification of testing

  11. KINETIC ANALYSIS OF BIOMOLECULAR INTERACTIONS USING LABEL-FREE BIOSENSORS

    E-Print Network [OSTI]

    Zhu, Xiangdong

    KINETIC ANALYSIS OF BIOMOLECULAR INTERACTIONS USING LABEL-FREE BIOSENSORS Yung-Shin Sun1 and X. D-free biosensors involves the monitoring of binding between biomolecules. However, a number of experimental may be avoided or resolved. Using a label-free oblique-incidence reflectivity difference biosensor

  12. Journal of Machine Learning Research 10 (2009) 2349-2374 Submitted 8/08; Revised 7/09; Published 10/09 Estimating Labels from Label Proportions

    E-Print Network [OSTI]

    Caetano, Tiberio

    2009-01-01

    /09 Estimating Labels from Label Proportions Novi Quadrianto NOVI.QUAD@GMAIL.COM Statistical Machine Learning observations, each set with known label proportions, predict the labels of another set of observations Learning (d) Learning from Proportions Figure 1: Different types of learning problems (colors encode class

  13. Holographic Labeling And Reading Machine For Authentication And Security Appications

    DOE Patents [OSTI]

    Weber, David C. (Rancho Santa Margarita, CA); Trolinger, James D. (Costa Mesa, CA)

    1999-07-06

    A holographic security label and automated reading machine for marking and subsequently authenticating any object such as an identification badge, a pass, a ticket, a manufactured part, or a package is described. The security label is extremely difficult to copy or even to read by unauthorized persons. The system comprises a holographic security label that has been created with a coded reference wave, whose specification can be kept secret. The label contains information that can be extracted only with the coded reference wave, which is derived from a holographic key, which restricts access of the information to only the possessor of the key. A reading machine accesses the information contained in the label and compares it with data stored in the machine through the application of a joint transform correlator, which is also equipped with a reference hologram that adds additional security to the procedure.

  14. Marketing off-label uses to physicians: FDA's draft (mis)guidance.

    E-Print Network [OSTI]

    Gass, Andy; Wilson, Jennifer

    2008-01-01

    and Stafford, R. S. 2006. Off-label prescribing among of?ce-Editorial Marketing Off-Label Uses to Physicians: FDAshibition against promoting off-label uses of drugs to physi-

  15. Monitoring folding pathways for large RNAs using site-directed spin-labeling techniques

    E-Print Network [OSTI]

    Zalma, Carre Alison

    2007-04-25

    -Directed Spin-Labeling (SDSL), in which nitroxyl spin-label probes are attached and observed by EPR spectroscopy. Spin-labels can provide information concerning structure and conformational changes because they are particularly sensitive to molecular motion...

  16. Status of the Local Enforcement of Energy Efficiency Standards and Labeling Program in China

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina; Fino-Chen, Cecilia; Fridley, David; Ning, Cao

    2011-09-26

    As part of its commitment to promoting and improving the local enforcement of appliance energy efficiency standards and labeling, the China National Institute of Standardization (CNIS) launched the National and Local Enforcement of Energy Efficiency Standards and Labeling project on August 14, 2009. The projects short-term goal is to expand the effort to improve enforcement of standards and labeling requirements to the entire country within three years, with a long-term goal of perfecting overall enforcement. For this project, Jiangsu, Shandong, Sichuan and Shanghai were selected as pilot locations. This report provides information on the local enforcement projects recent background, activities and results as well as comparison to previous rounds of check-testing in 2006 and 2007. In addition, the report also offers evaluation on the achievement and weaknesses in the local enforcement scheme and recommendations. The results demonstrate both improvement and some backsliding. Enforcement schemes are in place in all target cities and applicable national standards and regulations were followed as the basis for local check testing. Check testing results show in general high labeling compliance across regions with 100% compliance for five products, including full compliance for all three products tested in Jiangsu province and two out of three products tested in Shandong province. Program results also identified key weaknesses in labeling compliance in Sichuan as well as in the efficiency standards compliance levels for small and medium three-phase asynchronous motors and self-ballasted fluorescent lamps. For example, compliance for the same product ranged from as low as 40% to 100% with mixed results for products that had been tested in previous rounds. For refrigerators, in particular, the efficiency standards compliance rate exhibited a wider range of 50% to 100%, and the average rate across all tested models also dropped from 96% in 2007 to 63%, possibly due to the implementation of newly strengthened efficiency standards in 2009. Areas for improvement include: Greater awareness at the local level to ensure that all manufacturers register their products with the label certification project and to minimize their resistance to inspections; improvement of the product sampling methodology to include representative testing of both large and small manufacturers and greater standardization of testing tools and procedures; and continued improvement in local enforcement efforts.

  17. Check-Testing of Manufacturer Self Reported Labeling Data & Compliance with MEPS

    E-Print Network [OSTI]

    Zhou, Nan

    2008-01-01

    the Energy Label). Today, the Energy Label is applied toenergy and water are serious conservation topics in China today.minimum energy performance standards (MEPS) in 1989. Today,

  18. Got Organic Milk? Consumer Valuations of Milk Labels after the Implementation of the USDA Organic Seal

    E-Print Network [OSTI]

    Kiesel, Kristin; Villas-Boas, Sofia B

    2007-01-01

    to pay for genetically modified foods labels in a marketM.F. , and B. Roe. Genetically modified food labeling: The

  19. Impacts of China's Current Appliance Standards and LabelingProgram to 2020

    SciTech Connect (OSTI)

    Fridley, David; Aden, Nathaniel; Zhou, Nan; Lin, Jiang

    2007-03-03

    The report summarizes the history and nature of China sstandardsand labeling program in the Introduction in Section 1. Trends indomestic production, exports, penetration rates, unit energy consumptionand the history of S&L technical levels by product are discussed ingreat detail in Section 2. The national energy impactsanalysis found inSection 3 concludes that overall China s standards and labeling programsreduce total electricity consumption in 2020 by an annual 106 TWh, or 16percent of what would otherwise been expected in that year in the absenceof standards and labeling programs.In total, the report concludes thatthe S&L programs currently in place in China are expected to save acumulative 1143 TWh by 2020, or 9 percent of the cumulative consumptionof residential electricity to that year. In 2020 alone, annual savingsare expected to be equivalent to 11 percent of residential electricityuse. In average generation terms, this is equivalent to 27 1-GW coalfired plants that would have required around 75 million tonnes of coal tooperate.In comparison, savings from the US appliance standards programalone is expected to save 10 percent of residential electricityconsumption in 2020.

  20. Synthesis of labeled oxalic acid derivatives

    DOE Patents [OSTI]

    Martinez, Rodolfo A. (Santa Fe, NM); Unkefer, Clifford J. (Los Alamos, NM); Alvarez, Marc A. (Santa Fe, NM)

    2004-06-22

    The present invention is directed to labeled compounds, specifically ##STR1## where each C* is selected from the group consisting of a carbon-12, i.e., .sup.12 C, or a carbon-13, i.e., .sup.13 C and at least one C* is .sup.13 C, R.sup.1 is selected from the group of C.sub.1 -C.sub.4 lower alkyl and aryl, and X is selected from the group of --NR.sup.2 R.sup.3 where R.sup.2 and R.sup.3 are each independently selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl, --SR.sup.4 where R.sup.4 is selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl, and --OR.sup.5 where R.sup.5 is selected from the group of C.sub.1 -C.sub.4 lower alkyl, alkoxy and aryl with the proviso that when R.sup.1 is methyl then R.sup.5 is other than methyl, when R.sup.1 is ethyl then R.sup.5 is other than ethyl, and when R.sup.1 is benzyl then R.sup.5 is other than benzyl.

  1. Functionalized nanopipettes: toward label-free, single cell biosensors

    E-Print Network [OSTI]

    Actis, Paolo; Mak, Andy C.; Pourmand, Nader

    2010-01-01

    label-free, single cell biosensors Paolo Actis & Andy C.1], carbon nanotube biosensors [2], nanowires [3], and nano-use of nano- pipettes as biosensors. The applications of

  2. California Homebuyers Find More Value in Energy-Efficient Labeled...

    Office of Environmental Management (EM)

    Depending on what upgrades homeowners install, they can also receive up to 8,000 in rebates and up to 2,000 for earning a GreenPoint Rated label. The homeowners profiled have...

  3. Automatic labeling of contrastive word pairs from spontaneous spoken English

    E-Print Network [OSTI]

    Leonardo Badino; Clark, Robert A J

    2008-01-01

    This paper addresses the problem of automatically labeling contrast in spontaneous spoken speech, where contrast here is meant as a relation that ties two words that explicitly contrast with each other. Detection of contrast is certainly relevant...

  4. Automatic topic segmentation and labeling in multiparty dialogue

    E-Print Network [OSTI]

    Hsueh, Pei-Yun; Moore, Johanna D.

    2010-11-04

    This study concerns how to segment a scenario-driven multiparty dialogue and how to label these segments automatically. We apply approaches that have been proposed for identifying topic boundaries at a coarser level to ...

  5. Generation of museum web pages: The intelligent labelling explorer.

    E-Print Network [OSTI]

    Hitzeman, Janet; Mellish, Chris; Oberlander, Jon

    1997-01-01

    The first phase of the Intelligent Labelling Explorer project has built the ILEX-1.1 system, which uses artificial intelligence technology to generate descriptions of objects displayed in a museum gallery. Each description ...

  6. International Experience in Standards and Labeling Programs for Rice Cookers

    E-Print Network [OSTI]

    Zhou, Nan

    2008-01-01

    of cooked rice and energy saving. 3.3 Energy Saving LabelCookers 13 3.2 Energy Saving of Electric13 3.2.1 Energy Saving in Warm

  7. Sintered wire cesium dispenser photocathode

    DOE Patents [OSTI]

    Montgomery, Eric J; Ives, R. Lawrence; Falce, Louis R

    2014-03-04

    A photoelectric cathode has a work function lowering material such as cesium placed into an enclosure which couples a thermal energy from a heater to the work function lowering material. The enclosure directs the work function lowering material in vapor form through a low diffusion layer, through a free space layer, and through a uniform porosity layer, one side of which also forms a photoelectric cathode surface. The low diffusion layer may be formed from sintered powdered metal, such as tungsten, and the uniform porosity layer may be formed from wires which are sintered together to form pores between the wires which are continuous from the a back surface to a front surface which is also the photoelectric surface.

  8. Integrable perturbed magnetic fields in toroidal geometry: An exact analytical flux surface label for large aspect ratio

    SciTech Connect (OSTI)

    Kallinikos, N.; Isliker, H.; Vlahos, L.; Meletlidou, E.

    2014-06-15

    An analytical description of magnetic islands is presented for the typical case of a single perturbation mode introduced to tokamak plasma equilibrium in the large aspect ratio approximation. Following the Hamiltonian structure directly in terms of toroidal coordinates, the well known integrability of this system is exploited, laying out a precise and practical way for determining the island topology features, as required in various applications, through an analytical and exact flux surface label.

  9. Posting and Labeling for Radiological Control Guide for use with Title 10, Code of Federal Regulations, Part 835, Occupational Radiation Protection

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1999-05-24

    This Guide provides an acceptable methodology for establishing and operating a radiological hazard posting and labeling program that will comply with U.S. Department of Energy (DOE) requirements specified in Title 10 of the Code of Federal Regulations (CFR), Part 835, Occupational Radiation Protection Canceled by DOE G 441.1-1B.

  10. Requirements Evolution Empirical Analyses

    E-Print Network [OSTI]

    Felici, Massimo

    Requirements Evolution Empirical Analyses Massimo Felici 18 July 2001, ITC-IRST/ARS, Trento, Italy Massimo Felici Requirements Evolution ITC-IRST/ARS #12;Requirements Evolution 1 Overview Why Requirements Evolution? Empirical Requirements Evolution: Two Industrial Case Studies Discussion

  11. Portable microfluidic raman system for rapid, label-free early disease signature detection

    SciTech Connect (OSTI)

    Wu, Meiye; Davis, Ryan Wesley; Hatch, Anson

    2015-09-01

    In the early stages of infection, patients develop non-specific or no symptoms at all. While waiting for identification of the infectious agent, precious window of opportunity for early intervention is lost. The standard diagnostics require affinity reagents and sufficient pathogen titers to reach the limit of detection. In the event of a disease outbreak, triaging the at-risk population rapidly and reliably for quarantine and countermeasure is more important than the identification of the pathogen by name. To expand Sandia's portfolio of Biological threat management capabilities, we will utilize Raman spectrometry to analyze immune subsets in whole blood to rapidly distinguish infected from non-infected, and bacterial from viral infection, for the purpose of triage during an emergency outbreak. The goal of this one year LDRD is to determine whether Raman spectroscopy can provide label-free detection of early disease signatures, and define a miniaturized Raman detection system meeting requirements for low- resource settings.

  12. The use of labeled leucine in establishing the time of allanto-chorionic fusion in the female albino rat with reference to implantation

    E-Print Network [OSTI]

    Rutledge, James Edward

    1966-01-01

    THE USE OF LABELED LEUCINE IN ESTABLISHING THE TIME OF ALLANTO-CHORIONIC FUSION IN THE FEMALE ALBINO RA T WIT H RE FERE NC E T 0 IM PLANTA T I ON A Thesis By JAMES EDWARD RUTLEDGE Submitted to the Graduate College of the Texas ASSAM... University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE January 1966 Major Subject: Physiology of Reproduction THE USE OF LABELED LEUCINE IN ESTABLISHING THE TIME OF ALLANTO- CHORIONIC FUSION IN THE FEMALE ALBINO RAT...

  13. International Review of the Development and Implementation of Energy Efficiency Standards and Labeling Programs

    SciTech Connect (OSTI)

    Zhou, Nan; Zheng, Nina; Fridley, David

    2012-02-28

    Appliance energy efficiency standards and labeling (S&L) programs have been important policy tools for regulating the efficiency of energy-using products for over 40 years and continue to expand in terms of geographic and product coverage. The most common S&L programs include mandatory minimum energy performance standards (MEPS) that seek to push the market for efficient products, and energy information and endorsement labels that seek to pull the market. This study seeks to review and compare some of the earliest and most well-developed S&L programs in three countries and one region: the U.S. MEPS and ENERGY STAR, Australia MEPS and Energy Label, European Union MEPS and Ecodesign requirements and Energy Label and Japanese Top Runner programs. For each program, key elements of S&L programs are evaluated and comparative analyses across the programs undertaken to identify best practice examples of individual elements as well as cross-cutting factors for success and lessons learned in international S&L program development and implementation. The international review and comparative analysis identified several overarching themes and highlighted some common factors behind successful program elements. First, standard-setting and programmatic implementation can benefit significantly from a legal framework that stipulates a specific timeline or schedule for standard-setting and revision, product coverage and legal sanctions for non-compliance. Second, the different MEPS programs revealed similarities in targeting efficiency gains that are technically feasible and economically justified as the principle for choosing a standard level, in many cases at a level that no product on the current market could reach. Third, detailed survey data such as the U.S. Residential Energy Consumption Survey (RECS) and rigorous analyses provide a strong foundation for standard-setting while incorporating the participation of different groups of stakeholders further strengthen the process. Fourth, sufficient program resources for program implementation and evaluation are critical to the effectiveness of standards and labeling programs and cost-sharing between national and local governments can help ensure adequate resources and uniform implementation. Lastly, check-testing and punitive measures are important forms of enforcement while the cancellation of registration or product sales-based fines have also proven effective in reducing non-compliance. The international comparative analysis also revealed the differing degree to which the level of government decentralization has influenced S&L programs and while no single country has best practices in all elements of standards and labeling development and implementation, national examples of best practices for specific elements do exist. For example, the U.S. has exemplified the use of rigorous analyses for standard-setting and robust data source with the RECS database while Japan?s Top Runner standard-setting principle has motivated manufacturers to exceed targets. In terms of standards implementation and enforcement, Australia has demonstrated success with enforcement given its long history of check-testing and enforcement initiatives while mandatory information-sharing between EU jurisdictions on compliance results is another important enforcement mechanism. These examples show that it is important to evaluate not only the drivers of different paths of standards and labeling development, but also the country-specific context for best practice examples in order to understand how and why certain elements of specific S&L programs have been effective.

  14. Simple, rapid method for the preparation of isotopically labeled formaldehyde

    DOE Patents [OSTI]

    Hooker, Jacob Matthew (Port Jefferson, NY); Schonberger, Matthias (Mains, DE); Schieferstein, Hanno (Aabergen, DE); Fowler, Joanna S. (Bellport, NY)

    2011-10-04

    Isotopically labeled formaldehyde (*C.sup..sctn.H.sub.2O) is prepared from labeled methyl iodide (*C.sup..sctn.H.sub.3I) by reaction with an oxygen nucleophile having a pendant leaving group. The mild and efficient reaction conditions result in good yields of *C.sup..sctn.H.sub.2O with little or no *C isotopic dilution. The simple, efficient production of .sup.11CH.sub.2O is described. The use of the .sup.11CH.sub.2O for the formation of positron emission tomography tracer compounds is described. The reaction can be incorporated into automated equipment available to radiochemistry laboratories. The isotopically labeled formaldehyde can be used in a variety of reactions to provide radiotracer compounds for imaging studies as well as for scintillation counting and autoradiography.

  15. Semiconductor Quantum Rods as Single Molecule FluorescentBiological Labels

    SciTech Connect (OSTI)

    Fu, Aihua; Gu, Weiwei; Boussert, Benjamine; Koski, Kristie; Gerion, Daniele; Manna, Liberato; Le Gros, Mark; Larabell, Carolyn; Alivisatos, A. Paul

    2006-05-29

    In recent years, semiconductor quantum dots have beenapplied with great advantage in a wide range of biological imagingapplications. The continuing developments in the synthesis of nanoscalematerials and specifically in the area of colloidal semiconductornanocrystals have created an opportunity to generate a next generation ofbiological labels with complementary or in some cases enhanced propertiescompared to colloidal quantum dots. In this paper, we report thedevelopment of rod shaped semiconductor nanocrystals (quantum rods) asnew fluorescent biological labels. We have engineered biocompatiblequantum rods by surface silanization and have applied them fornon-specific cell tracking as well as specific cellular targeting. Theproperties of quantum rods as demonstrated here are enhanced sensitivityand greater resistance for degradation as compared to quantum dots.Quantum rods have many potential applications as biological labels insituations where their properties offer advantages over quantumdots.

  16. Competition Requirements | Department of Energy

    Office of Environmental Management (EM)

    Competition Requirements Competition Requirements Competition Requirements More Documents & Publications Competition Requirements Attachment FY2011-40(2) Competition Requirements...

  17. Volume-labeled nanoparticles and methods of preparation

    DOE Patents [OSTI]

    Wang, Wei; Gu, Baohua; Retterer, Scott T; Doktycz, Mitchel J

    2015-04-21

    Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.

  18. Balanced steady state free precession for arterial spin labeling MRI: Initial experience for blood flow mapping in human brain, retina, and kidney

    E-Print Network [OSTI]

    Park, S-H; Wang, DJJ; Duong, TQ

    2013-01-01

    repeated once (Label On 2 and Label Off 2), for con?rmationblood ?ow image without tagging power (Label Off 1). These

  19. Palladium-Mediated Cell-Surface Labeling Christopher D. Spicer,

    E-Print Network [OSTI]

    Davis, Ben G.

    Palladium-Mediated Cell-Surface Labeling Christopher D. Spicer, Therese Triemer, and Benjamin G. Palladium-mediated reactions have revolutionized modern synthetic chemistry but have yet to find broad-Miyaura chemistry into a cellular context, demonstrate low toxicity at effective palladium loadings, and confirm

  20. Efficient Algorithms for Exact Inference in Sequence Labeling SVMs

    E-Print Network [OSTI]

    Freytag, Johann-Christoph

    1 Efficient Algorithms for Exact Inference in Sequence Labeling SVMs Alexander Bauer, Nico Gornitz, Franziska Biegler, Klaus-Robert Muller, and Marius Kloft Abstract--The task of structured output prediction or segmentation of the sequence. A proven methodology to this end consists in A. Bauer is with Machine Learning

  1. RAMSEY DEGREES, LABELED AND UNLABELED PARTITIONS MIODRAG SOKIC

    E-Print Network [OSTI]

    Sokic, Miodrag

    RAMSEY DEGREES, LABELED AND UNLABELED PARTITIONS MIODRAG SOKI´C Abstract. Let K be a class.e. an equivalence relation, to structures in K. We calculate Ramsey degrees for structures in Kn and EK. In addition such that C ! (B)A r , then we say that K is a Ramsey class or that K satis...es the Ramsey property (RP

  2. Efficient Algorithms for Exact Inference in Sequence Labeling SVMs

    E-Print Network [OSTI]

    Freytag, Johann-Christoph

    1 Efficient Algorithms for Exact Inference in Sequence Labeling SVMs Alexander Bauer, Nico G¨ornitz, Franziska Biegler, Klaus-Robert M¨uller, and Marius Kloft Abstract--The task of structured output prediction or segmentation of the sequence. A proven methodology to this end consists in A. Bauer is with Machine Learning

  3. SVM for Learning with Label Proportions Felix X. Yu

    E-Print Network [OSTI]

    Cortes, Corinna

    SVM for Learning with Label Proportions Felix X. Yu yuxinnan@ee.columbia.edu Dong Liu dongliu of learning with la- bel proportions in which the training data is provided in groups and only the propor- tion of each class in each group is known. We propose a new method called proportion- SVM, or SVM

  4. Pesticide Labeling: Directions for Use1 Frederick M. Fishel2

    E-Print Network [OSTI]

    Hill, Jeffrey E.

    in the product's new formulation in order to save money on the cost of shipping supplies of product to retail agrichemical dealers. If only the manager and employee had reviewed the content of the new label, most often the pesticide should or may be applied. All restricted entry intervals (REIs) pertaining

  5. DETECTING ABNORMAL FISH TRAJECTORIES USING CLUSTERED AND LABELED DATA

    E-Print Network [OSTI]

    Fisher, Bob

    DETECTING ABNORMAL FISH TRAJECTORIES USING CLUSTERED AND LABELED DATA Cigdem Beyan, Robert B We propose an approach for the analysis of fish trajectories in unconstrained underwater videos. Trajectories are classified into two classes: normal trajectories which contain the usual behavior of fish

  6. Palladium-109 labeled anti-melanoma monoclonal antibodies

    DOE Patents [OSTI]

    Srivastava, S.C.; Fawwaz, R.A.; Ferrone, S.

    1984-04-30

    The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)

  7. Open Domain Information Extraction via Automatic Semantic Labeling Alessandro Moschitti

    E-Print Network [OSTI]

    Moschitti, Alessandro

    of Computer Science Systems and Production University of Rome Tor Vergata 00133 Rome (Italy) moschitti@info by the labels are generated auto- matically with a high precision. Keywords: Natural Language Processing of automatically identifying information of interest from the vast Internet resources is by employing Information

  8. Calendar Year 2008 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Homan, GregoryK; Sanchez, Marla; Brown, RichardE; Lai, Judy

    2010-08-24

    This paper presents current and projected savings for ENERGY STAR labeled products, and details the status of the model as implemented in the September 2009 spreadsheets. ENERGY STAR is a voluntary energy efficiency labeling program operated jointly by the Environmental Protection Agency (US EPA) and the U.S. Department of Energy (US DOE), designed to identify and promote energy-efficient products, buildings and practices. Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products, and currently labels more than thirty products, spanning office equipment, heating, cooling and ventilation equipment, commercial and residential lighting, home electronics, and major appliances. ENERGY STAR's central role in the development of regional, national and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with stakeholders. This report presents savings estimates for ENERGY STAR labeled products. We present estimates of energy, dollar, and carbon savings achieved by the program in the year 2008, annual forecasts for 2009 and 2010, and cumulative savings estimates for the period 1993 through 2008 and cumulative forecasts for the period 2009 through 2015. Through 2008 the program saved 8.8 Quads of primary energy and avoided the equivalent of 158 metric tones carbon (MtC). The forecast for the period 2009-2015 is 18.1 Quads or primary energy saved and 316 MtC emissions avoided. The sensitivity analysis bounds the best estimate of carbon avoided between 104 MtC and 213 MtC (1993 to 2008) and between 206 MtC and 444 MtC (2009 to 2015). In this report we address the following questions for ENERGY STAR labeled products: (1) How are ENERGY STAR impacts quantified; (2) What are the ENERGY STAR achievements; and (3) What are the limitations to our method?

  9. Quantifying Peptides in Isotopically Labeled Protease Digests by Ion Mobility/Time-of-Flight

    E-Print Network [OSTI]

    Clemmer, David E.

    Quantifying Peptides in Isotopically Labeled Protease Digests by Ion Mobility/Time-of-Flight Mass-terminus can be accomplished by digesting proteins in 18O-labeled water,11-20 resulting in incorpora- tion

  10. Canada's Tobacco Package Label or Warning System: "Telling the Truth" about Tobacco Product Risks

    E-Print Network [OSTI]

    Mahood, Garfield; World Health Organization

    2003-01-01

    interest in tobacco package labelling or warning systems (labelling reform came from three princi- pal sources: the three major Canadian manufacturers, the Canadian Tobacco Manufacturers Council, and tobacco package

  11. Evaluation of Local Enforcement of Energy Efficiency Standards and Labeling Program in China

    E-Print Network [OSTI]

    Zheng, Nina

    2013-01-01

    National and Local Enforcement of Energy Efficiency Standards and Labeling Program (National and Local Enforcement of Energy Efficiency Standards and Labeling ProgramNational Laboratory Preprint version of paper for Proceedings of 2012 International Energy Program

  12. International Review of the Development and Implementation of Energy Efficiency Standards and Labeling Programs

    E-Print Network [OSTI]

    Zhou, Nan

    2013-01-01

    Program of Mandatory Labeling and Minimum Energy Performance Standards Editionedition). Washington, DC: Collaborative Labeling and Appliance Standards Program (Program: Developing the Worlds best Energy-Efficient Appliances (Revised edition

  13. A Rate of Convergence for Mixture Proportion Estimation, with Application to Learning from Noisy Labels

    E-Print Network [OSTI]

    Scott, Clayton

    A Rate of Convergence for Mixture Proportion Estimation, with Application to Learning from Noisy Labels Clayton Scott University of Michigan, Department of EECS Abstract Mixture proportion estimation efficacy in classification with noisy labels. 1 Introduction Mixture proportion estimation (MPE

  14. Department of Energy to Take Steps to Remove ENERGY STAR Label...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to Take Steps to Remove ENERGY STAR Label on Certain LG Refrigerator-Freezer Models Department of Energy to Take Steps to Remove ENERGY STAR Label on Certain LG...

  15. Got Organic Milk? Consumer Valuations of Milk Labels after the Implementation of the USDA Organic Seal

    E-Print Network [OSTI]

    Kiesel, Kristin; Villas-Boas, Sofia B

    2007-01-01

    and Hicks (2002) report that dolphin-safe labels resulted in changes in aggregate tuna consumption, and Jin and Leslie (

  16. Methods to radiolabel natural organic matter by reduction with hydrogen labeled reducing agents

    DOE Patents [OSTI]

    Tinnacher, Ruth M.; Honeyman, Bruce D.

    2011-10-18

    Methods to radiolabel natural organic matter by reduction with a hydrogen labeled reducing agent, and compositions, are provided.

  17. Status of China's Energy Efficiency Standards and Labels for Appliances and International Collaboration

    E-Print Network [OSTI]

    Zhou, Nan

    2010-01-01

    the Energy La- bel). Today, the Energy Label is applied tominimum energy performance standards (MEPS) in 1989. Today,

  18. The Practice and Thinking of Building Energy Efficiency Evaluation & Labeling in Shanghai

    Office of Energy Efficiency and Renewable Energy (EERE)

    Information about the development of Building Energy Efficiency Evaluation and Labeling in Shanghai with project examples and theory.

  19. A New Generation of Labels for a New Generation of Cars

    Broader source: Energy.gov [DOE]

    New fuel economy labels help consumers go beyond the sticker price and determine lifetime cost of a vehicle.

  20. Assay for vitamin B12 absorption and method of making labeled vitamin B12

    SciTech Connect (OSTI)

    Anderson, Peter J.; Dueker, Stephen; Miller, Joshua; Green, Ralph; Roth, John; Carkeet, Colleen; Buchholz,; Bruce A.

    2012-06-19

    The invention provides methods for labeling vitamin B12 with .sup.14C, .sup.13C, tritium, and deuterium. When radioisotopes are used, the invention provides for methods of labeling B12 with high specific activity. The invention also provides labeled vitamin B12 compositions made in accordance with the invention.

  1. packaged foods followed food labeling changes that went into effect in 2006.1

    E-Print Network [OSTI]

    packaged foods followed food labeling changes that went into effect in 2006.1 Further labeling for a product labeled zero trans fat to have close to 0.5 g of trans fat per serving, we are unaware of any pub packaged foods would elimi- nate these differences and would help persons who may only have access

  2. On the Utility of Abstraction in Labeling Actors in Social Networks Computer Science Department

    E-Print Network [OSTI]

    Honavar, Vasant

    such that actors are associated with labels that can be in many forms: labels which denote political or religiousOn the Utility of Abstraction in Labeling Actors in Social Networks Ngot Bui Computer Science--Social networks are naturally represented as het- erogeneous networks with multiple types of objects e.g., actors

  3. Automatic Semantic Labelling of Urban Areas using a rule-based

    E-Print Network [OSTI]

    Automatic Semantic Labelling of Urban Areas using a rule-based approach and realized with Me and the actual implementation of a model to perform an automatic semantic labelling of urban areas. For this assignment we looked at automatic semantic labelling of very high resolution airborne images (derived ortho

  4. An Improved Labelling for the INRIA Person Data Set for Pedestrian Detection

    E-Print Network [OSTI]

    Instituto de Sistemas e Robotica

    An Improved Labelling for the INRIA Person Data Set for Pedestrian Detection Matteo Taiana, Jacinto is very popular in the Pedestrian Detection community, both for training detectors and reporting results. Yet, the labelling of its test set has some limitations: some of the pedestrians are not labelled

  5. CRITERIA FOR LABELLING PROSODIC ASPECTS OF ENGLISH SPEECH Paul C. Bagshaw Briony J. Williams

    E-Print Network [OSTI]

    Edinburgh, University of

    unit [4]. This definition of nuclear syllables and the criteria used to determine sylCRITERIA FOR LABELLING PROSODIC ASPECTS OF ENGLISH SPEECH Paul C. Bagshaw Briony J. Williams Centre ABSTRACT We report a set of labelling criteria which have been developed to label prosodic events in clear

  6. Government Printing Office Requirements

    Broader source: Energy.gov [DOE]

    This section describes the Government Printing Office (GPO) requirements for all print materials, whether printed electronically or on paper. This includes requirements for printing and copying for...

  7. Indium-111-labeled platelets in monitoring human pancreatic transplants

    SciTech Connect (OSTI)

    Catafau, A.M.; Lomena, F.J.; Ricart, M.J.; Pons, F.; Piera, C.; Pavia, J.; Moragas, M.; Garcia, A.; Herranz, R.; Andreu, J. (Nuclear Medicine Service, Barcelona (Spain))

    1989-09-01

    We have performed 59 {sup 111}In-labeled platelet scintigraphies in 12 patients with pancreas transplant, and we have compared retrospectively the {sup 111}In platelet uptake with the graft immunological situation. A diffuse uptake in the graft was seen in five of six patients with pancreatic rejection. The scans became positive before changes in biochemical tests were detected. No {sup 111}In platelet uptake was seen in five of seven normally functioning grafts. Two cases of venous thrombosis and two perigraft hematomas appeared like a focal {sup 111}In platelet accumulation. Indium-111-labeled platelet scintigraphy can be a useful method for monitoring pancreas transplants. It may be helpful in the early detection of pancreatic allograft rejection and in the differential diagnosis between this and other complications such as thrombosis or hematomas.

  8. Cerebral perfusion imaging with iodine 123-labeled amines

    SciTech Connect (OSTI)

    Holman, B.L.; Hill, T.C.; Polak, J.F.; Lee, R.G.; Royal, H.D.; O'Leary, D.H.

    1984-10-01

    Two amines, N-isopropyl p-iodoamphetamine and N,N,N'-trimethyl-N'-(2-hydroxyl-3-methyl-5-iodobenzyl)-1,3-prop anediamine, have been labeled with iodine 123. The brain uptake of these radioactive tracers is proportional to cerebral blood flow. These tracers are retained in the brain for a sufficiently long time so that imaging can be performed with standard, readily available instrumentation. Transaxial tomography with amines is useful in acute cerebral infarction, in which the x-ray computed tomographic scan may be normal for several days after onset of symptoms while the uptake of radioisotope-labeled amines will be altered immediately after the onset of the stroke. It is also useful in examining patients with cerebral vascular disease and in the preoperative examination of patients with partial epilepsy.

  9. Global Potential of Energy Efficiency Standards and Labeling Programs

    SciTech Connect (OSTI)

    McNeil, Michael A; McNeil, Michael A.; Letschert, Virginie; de la Rue du Can, Stephane

    2008-06-15

    This report estimates the global potential reductions in greenhouse gas emissions by 2030 for energy efficiency improvements associated with equipment (appliances, lighting, and HVAC) in buildings by means of energy efficiency standards and labels (EES&L). A consensus has emerged among the world's scientists and many corporate and political leaders regarding the need to address the threat of climate change through emissions mitigation and adaptation. A further consensus has emerged that a central component of these strategies must be focused around energy, which is the primary generator of greenhouse gas emissions. Two important questions result from this consensus: 'what kinds of policies encourage the appropriate transformation to energy efficiency' and 'how much impact can these policies have'? This report aims to contribute to the dialogue surrounding these issues by considering the potential impacts of a single policy type, applied on a global scale. The policy addressed in this report is Energy Efficient Standards and Labeling (EES&L) for energy-consuming equipment, which has now been implemented in over 60 countries. Mandatory energy performance standards are important because they contribute positively to a nation's economy and provide relative certainty about the outcome (both timing and magnitudes). Labels also contribute positively to a nation's economy and importantly increase the awareness of the energy-consuming public. Other policies not analyzed here (utility incentives, tax credits) are complimentary to standards and labels and also contribute in significant ways to reducing greenhouse gas emissions. We believe the analysis reported here to be the first systematic attempt to evaluate the potential of savings from EES&L for all countries and for such a large set of products. The goal of the analysis is to provide an assessment that is sufficiently well-quantified and accurate to allow comparison and integration with other strategies under consideration.

  10. Fluorescent Labeling Reagents Optimized for Capillary Electrophoretic Separations

    E-Print Network [OSTI]

    Estrada, Roy Tonacao, III

    2012-02-14

    molecules fluoresce, background noise from the separation matrix and other extraneous compounds is usually a problem. Moreover, UV lasers tend to be more expensive than those used in the visible region [8]. To go around the background noise problem..., excitation can be done in the visible or higher wavelengths. However, only a very small number of proteins have native fluorescence above the UV region. To effectively use LIF as a detection method, proteins have to be labeled with fluorophores that can...

  11. Labelling Wheels for Minimum Sum Number Mirka MILLER Joseph RYAN

    E-Print Network [OSTI]

    Smyth, William F.

    and Smyth showed that for wheels W n of order n+1 and size m = 2n, oe(W n ) 2 \\Theta(m); that is these results to show that for even n ?? 4, oe(W n ) = n=2 + 2, while for odd n ?? 5 we disprove a conjecture of Hartsfield and Smyth by showing that oe(W n ) = n. Labellings are given that achieve these minima. 1

  12. Labeled ALPHA4BETA2 ligands and methods therefor

    DOE Patents [OSTI]

    Mukherjee, Jogeshwar; Pichika, Ramaiah; Potkin, Steven; Leslie, Frances; Chattopadhyay, Sankha

    2013-02-19

    Contemplated compositions and methods are employed to bind in vitro and in vivo to an .alpha.4.beta.2 nicotinic acetylcholine receptor in a highly selective manner. Where such compounds are labeled, compositions and methods employing such compounds can be used for PET and SPECT analysis. Alternatively, and/or additionally contemplated compounds can be used as antagonists, partial agonists or agonists in the treatment of diseases or conditions associated with .alpha.4.beta..beta.2 dysfunction.

  13. Calendar Year 2009 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Homan, Gregory K; Sanchez, Marla C.; Brown, Richard E.

    2010-11-15

    ENERGY STAR is a voluntary energy efficiency labeling program operated jointly by the Environmental Protection Agency (US EPA) and the U.S. Department of Energy (US DOE), designed to identify and promote energy-efficient products, buildings and practices. Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products, and currently labels more than thirty products, spanning office equipment, heating, cooling and ventilation equipment, commercial and residential lighting, home electronics, and major appliances. ENERGY STAR's central role in the development of regional, national and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with stakeholders. This report presents savings estimates from the use ENERGY STAR labeled products. We present estimates of energy, dollar, and carbon savings achieved by the program in the year 2009, annual forecasts for 2010 and 2011, and cumulative savings estimates for the period 1993 through 2009 and cumulative forecasts for the period 2010 through 2015. Through 2009 the program saved 9.5 Quads of primary energy and avoided the equivalent of 170 million metric tons carbon (MMTC). The forecast for the period 2009-2015 is 11.5 Quads or primary energy saved and 202 MMTC emissions avoided. The sensitivity analysis bounds the best estimate of carbon avoided between 110 MMTC and 231 MMTC (1993 to 2009) and between 130 MMTC and 285 MMTC (2010 to 2015).

  14. 3. MATERIAL CERTIFICATIONS REQUIRED NO RADIOGRAPHY REQUIRED.

    E-Print Network [OSTI]

    McDonald, Kirk

    SHALL BE DYE PENETRANT INSPECTED. ASME SECTION IX. NO CODE STAMP REQUIRED. 1. WELDING TO BE PERFORMED is property of 1. ALL DIMENSIONS ARE IN INCHES 2. INTERPRET DIMENSIONS AND TOLERANCES PER ASME Y14.5M 3

  15. Labelled biomolecules with sup 1 sup 5 sup 3 Sm, sup 1 sup 8 sup 8 Re, and sup 9 sup 0 Y for targeted radiotherapy

    E-Print Network [OSTI]

    Mushtaq, A; Perverz, S

    1998-01-01

    A somatostatin analogue Lanreotide was labelled with sup 1 sup 8 sup 8 Re, sup 9 sup 9 Tc sup m and sup 1 sup 3 sup 1 I. Labelling was accomplished by reduction of cysteine bridge, which provided sulfhydryl groups for chelation with sup 1 sup 8 sup 8 Re/ sup 9 sup 9 Tc sup m. Stannous chloride was used as reducing agent, while tartrate acted as transchelating agent. The lower redox potential of ReO sub 4 sup - than TcO sub 4 sup - required the addition of excess SnCl sub 2 and medium-chelating agent for stabilizing the excess of SnCl sub 2 in solution. ITLC and HPLC techniques employed for monitoring the labelling yield revealed >95% labelling efficiency. Radioiodination of lanreotide was carried out by Chloramine-T and iodogen methods. The radiolabelling yield varied between 40-80%. Chloramine-T method was found more suitable than Iodogen method, because approx 25% of the initial iodine activity was adsorbed on Iodogen coating. Avidin-biotin system is widely used in medical research, especially in pretargete...

  16. Requirement Required Course Required Course English Composition: ENG 101 3

    E-Print Network [OSTI]

    Walker, Lawrence R.

    (4) 3 MATH _____ 3 MATH 427 Differential Equations 3 (1A) 3 MATH 453 Abstract Algebra 3 (1B) 3 MATH requirement MATH 181 Calculus I below see course choices www.unlv.edu/committees/gec 3* 1 MATH 181 Calculus I 4 MATH 182 Calculus II 4 (1) 3 MATH 251 Discrete Mathematics I 3 (2) 3 MATH 283 Calculus III 4 (3) 3

  17. Emergency Medical Treatment Required

    E-Print Network [OSTI]

    McQuade, D. Tyler

    Emergency Medical Treatment Required Non-Emergency Medical Treatment Required If possible, get help from colleague or supervisor Call 911 or go to hospital emergency room (for chemical exposure, bring Investigation Report" to Environmental Health & Safety within 48 hours Emergency Medical Treatment Required

  18. Remember that the pesticide label is the legal document on pesticide use. Read the label and follow all instructions closely. The use of a pesticide in a manner not consistent with the label can lead to the injury of

    E-Print Network [OSTI]

    Douches, David S.

    lead to the injury of crops, humans, animals and the environment. The use of a pesticide inconsistent with the label directions can also lead to civil or criminal fines and/or condemnation of the crop. Pesticides

  19. Marketing off-label uses to physicians: FDA's draft (mis)guidance.

    E-Print Network [OSTI]

    Gass, Andy; Wilson, Jennifer

    2008-01-01

    De Angelis, C. D. 2004. Post- marketing surveillancelack of10.1080/15265160802116624 Editorial Marketing Off-Label Usesacknowledg- ing that such marketing efforts technically may

  20. A New Framework for Approximate Labeling via Graph Cuts Nikos Komodakis, Georgios Tziritas

    E-Print Network [OSTI]

    Tziritas, Georgios

    (f). The cost C(f) = pV cp,f(p) + (p,q)E wpqdf(p)f(q) con- sists of 2 parts. On one hand, for each p V V of objects and a set L of labels the goal is to find a labeling f : V L with a minimum cost C there is a label cost cp,f(p) 0 for assigning label f(p) to p. On the other hand, for each pair of objects p, q

  1. Graphene-Plasmonic Hybrid Platform for Label-Free SERS Biomedical Detection

    E-Print Network [OSTI]

    Wang, Pu

    2015-01-01

    silver nanoparticle hybrids for ultrasensitive single-optical anisotropy in hybrid graphene-metal nanoparticlesensitive graphene-plasmonic hybrid platform for label-free

  2. Energy Efficiency Standards and Labels in North America: Opportunities for Harmonization

    E-Print Network [OSTI]

    Wiel, Stephen

    2008-01-01

    and Equipment Energy Efficiency Committee. Available fromE. McMahon. 2001. Energy-Efficiency Labels and Standards: ALloyd. 1999. Review of energy efficiency test standards and

  3. International Review of the Development and Implementation of Energy Efficiency Standards and Labeling Programs

    E-Print Network [OSTI]

    Zhou, Nan

    2013-01-01

    National Appliance and Equipment Energy Efficiency Program (national and regional emphasis on energy conservation and efficiency programs.on energy labels, consolidated under national program in

  4. 2007 Status Report: Savings Estimates for the ENERGY STAR(R) VoluntaryLabeling Program

    E-Print Network [OSTI]

    Sanchez, Marla; Webber, Carrie A.; Brown, Richard E.; Homan, Gregory K.

    2007-01-01

    analyzed in five parts: machine, electric water heating, gasmachine energy, which accrued to all devices, electric waterand electric fryers as Energy Star labeled products. Cold beverage vending machines

  5. 2005 Status Report Savings Estimates for the ENERGY STAR(R) Voluntary Labeling Program

    E-Print Network [OSTI]

    Webber, Carrie A.; Brown, Richard E.; Sanchez, Marla

    2006-01-01

    analyzed in five parts: machine, electric water heating, gasmachine energy, which accrued to all devices, electric waterand electric fryers as Energy Star labeled products. Cold beverage vending machines

  6. 2006 Status Report Savings Estimates for the ENERGY STAR(R) Voluntary Labeling Program

    E-Print Network [OSTI]

    Webber, Carrie A.; Brown, Richard E.; Sanchez, Marla; Homan, Gregory K.

    2006-01-01

    analyzed in five parts: machine, electric water heating, gasmachine energy, which accrued to all devices, electric waterand electric fryers as Energy Star labeled products. Cold beverage vending machines

  7. Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture

    DOE Patents [OSTI]

    Sanfilippo, Antonio (Richland, WA); Calapristi, Augustin J. (West Richland, WA); Crow, Vernon L. (Richland, WA); Hetzler, Elizabeth G. (Kennewick, WA); Turner, Alan E. (Kennewick, WA)

    2009-12-22

    Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture are described. In one aspect, a document clustering method includes providing a document set comprising a plurality of documents, providing a cluster comprising a subset of the documents of the document set, using a plurality of terms of the documents, providing a cluster label indicative of subject matter content of the documents of the cluster, wherein the cluster label comprises a plurality of word senses, and selecting one of the word senses of the cluster label.

  8. Prime Number-Based Hierarchical Data Labeling Scheme for Relational Databases

    E-Print Network [OSTI]

    Morozov, Serhiy

    2007-12-13

    reusable prime number labeling (rPNL) that reduces the effects of the mentioned weaknesses. The proposed scheme advantage is discussed in detail, proven mathematically, and experimentally confirmed....

  9. Impacts of China's Current Appliance Standards and Labeling Program to 2020

    E-Print Network [OSTI]

    Fridley, David; Aden, Nathaniel; Zhou, Nan; Lin, Jiang

    2007-01-01

    using the "Long Range Energy Alternatives Planning" (LEAP)using the "Long Range Energy Alternatives Planning" LabelLEAP (Long-range Energy Alternative Planning System) was

  10. Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification

    E-Print Network [OSTI]

    Scott, Matthew

    Gli functions. Ptc1 / mutants develop floor plate, motor neuron, and V3 interneuron progenitors3 are involved in neural tube development, whereas Gli1 is dispensable (Ding et al., 1998; Theil et

  11. Requirement of a Tha4-conserved Transmembrane Glutamate in Thylakoid Tat Translocase Assembly Revealed by

    E-Print Network [OSTI]

    is dispensable and the amphipathic helix essential for transport. We then investigated a conserved Tha4 that serves as a protein- conducting channel and SecA, an ATP-driven motor that ``pushes'' proteins

  12. Regulators, Requirements, Statutes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regulations and the New Mexico Administrative Code. Federal Requirements The Environmental Protection Agency (EPA) enforces the federal regulations. Code of Federal...

  13. Transuranic Waste Requirements

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1999-07-09

    The guide provides criteria for determining if a waste is to be managed in accordance with DOE M 435.1-1, Chapter III, Transuranic Waste Requirements.

  14. Web Writing Requirements

    Broader source: Energy.gov [DOE]

    When writing content for Office of Energy Efficiency and Renewable Energy (EERE) websites and applications, follow these requirements. Also see EERE's Web writing best practices.

  15. Residential Solar Permit Requirements

    Broader source: Energy.gov [DOE]

    Washington's State Building Code sets requirements for the installation, inspection, maintenance and repair of solar photovoltaic (PV) energy systems. Local jurisdictions have the authority to is...

  16. Required Annual Notices

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Required Annual Notices The Women's Health and Cancer Rights Act of 1998 (WHCRA) The medical programs sponsored by LANS will not restrict benefits if you or your dependent...

  17. Vitamin and mineral requirements

    E-Print Network [OSTI]

    Laughlin, Robert B.

    Vitamin and mineral requirements in human nutrition Second edition Please go to the Table/WHO Expert Consultation on Human Vitamin and Mineral Requirements (1998 : Bangkok, Thailand). Vitamin, 2130 September 1998. 1.Vitamins -- standards 2.Micronutrients -- standards 3.Trace elements

  18. General Responsibilities and Requirements

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1999-07-09

    The material presented in this guide provides suggestions and acceptable ways of implementing DOE M 435.1-1 and should not be viewed as additional or mandatory requirements. The objective of the guide is to ensure that responsible individuals understand what is necessary and acceptable for implementing the requirements of DOE M 435.1-1.

  19. Information Technology Requirements

    E-Print Network [OSTI]

    Saskatchewan, University of

    -campus Televised Multi-mode Independent Study Web-based Other (specify) 3. Network Requirements 3.1 Does;General Web and e-mail usage Large (10MB or more) file transfers Other (specify) 3.2 Does the program list the software that will be required for the program (e.g. e-mail, web pages, SPSS, discipline

  20. NISTIR 7933 Requirements and

    E-Print Network [OSTI]

    NISTIR 7933 Requirements and Conformance Test Assertions for ANSI/NIST-ITL 1-2011 Record Type 18 #12;ii NISTIR 7933 Requirements and Conformance Test Assertions for ANSI/NIST-ITL 1-2011 Record Type/CTS designed to test implementations of ANSI/NIST-ITL 1- 2011 (AN-2011) "Data Format for the Interchange

  1. State feedback control of labeled Petri nets with uncertainty in the initial marking

    E-Print Network [OSTI]

    Hadjicostis, Christoforos

    State feedback control of labeled Petri nets with uncertainty in the initial marking Maria Paola feedback controller for a labeled Petri net whose ini- tial marking is known to belong to a given convex vehicles, com- munication networks, and so on. In this paper we deal with the problem of designing a state

  2. Optical Label Switching Technology and Energy-Efficient Future Networks S. J. Ben Yoo

    E-Print Network [OSTI]

    Yoo, S. J. Ben

    Optical Label Switching Technology and Energy-Efficient Future Networks S. J. Ben Yoo Department traffic with extremely low energy consumption and high goodput. Keywords: Optical packet switching, optical label switching, energy efficient networks. 1. Introduction The future Internet is rapidly

  3. Introduction Basic Structure Symmetries Labelling and Potential Energy Future Work Geometry from Chemistry II

    E-Print Network [OSTI]

    Broughton, S. Allen

    Introduction Basic Structure Symmetries Labelling and Potential Energy Future Work Geometry from and Potential Energy local potential energy terms 5 Future Work #12;Introduction Basic Structure Symmetries Labelling and Potential Energy Future Work nanotubes nanotube - cartoon picture - 1 Here is a cartoon model

  4. Label Noise-Tolerant Hidden Markov Models for Segmentation: Application to ECGs

    E-Print Network [OSTI]

    Verleysen, Michel

    Label Noise-Tolerant Hidden Markov Models for Segmentation: Application to ECGs Beno^it Frenay, Ga classification models can ad- versely be impacted by the presence of label noise in training observa- tions by incorporating a statistical noise model within the inference algorithm. In this paper, the specific case

  5. Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI in Alzheimer's

    E-Print Network [OSTI]

    Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI arterial spin labeling (CASL) magnetic resonance imaging (MRI) was combined with multivariate analysis and precuneus. When tested on extensive split-half analysis to map out the replicability of both multivariate

  6. Optical Arbitrary Waveform Generation Based Optical-Label Switching Transmitter with

    E-Print Network [OSTI]

    Kolner, Brian H.

    Optical Arbitrary Waveform Generation Based Optical-Label Switching Transmitter with All-Optical, 95616 Email: sbyoo@ucdavis.edu Abstract: This paper introduces a modulation-format transparent optical-label switching transmitter based on optical arbitrary waveform generation. Packets consisting of 100 Gb

  7. Optical-Label Switching, MPLS, MPLambdaS and GMPLS S. J. B. Yoo

    E-Print Network [OSTI]

    Kolner, Brian H.

    Optical-Label Switching, MPLS, MPLambdaS and GMPLS S. J. B. Yoo Department of Electrical), yoo@ece.ucdavis.edu ABSTRACT This paper discusses the new architecture and protocol of Optical characteristics of Optical-Label switching indicate its support of diverse QoS, CoS, and ToS services while

  8. Sub-Lithographic Patterning Technology for Nanowire Model Catalysts and DNA Label-Free Hybridization Detection

    E-Print Network [OSTI]

    Bokor, Jeffrey

    Sub-Lithographic Patterning Technology for Nanowire Model Catalysts and DNA Label were used as a mold in nanoimprint lithography and lift-off patterning of sub-30nm platinum nanowires a label-free tool for DNA hybridization detection based on measuring capacitance changes in the gap

  9. Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical

    E-Print Network [OSTI]

    Zhu, Xiangdong

    Oblique-incidence reflectivity difference microscope for label-free high-throughput detection (OI-RD) microscope, a form of polarization-modulated imaging ellipsometer, for label on the polarizer compensatorsampleanalyzer scheme and under the off-null condition, a polarization-modulated OI

  10. The Cannon: A data-driven approach to stellar label determination

    E-Print Network [OSTI]

    Ness, Melissa; Rix, Hans-Walter; Ho, Anna; Zasowski, Gail

    2015-01-01

    New spectroscopic surveys offer the promise of consistent stellar parameters and abundances ('stellar labels') for hundreds of thousands of stars in the Milky Way: this poses a formidable spectral modeling challenge. In many cases, there is a sub-set of reference objects for which the stellar labels are known with high(er) fidelity. We take advantage of this with The Cannon, a new data-driven approach for determining stellar labels from spectroscopic data. The Cannon learns from the 'known' labels of reference stars how the continuum-normalized spectra depend on these labels by fitting a flexible model at each wavelength; then, The Cannon uses this model to derive labels for the remaining survey stars. We illustrate The Cannon by training the model on only 543 stars in 19 clusters as reference objects, with Teff, log g and [Fe/H] as the labels, and then applying it to the spectra of 56,000 stars from APOGEE DR10. The Cannon is very accurate. Its stellar labels compare well to the stars for which APOGEE pipeli...

  11. Eco-labeling Strategies and Price-Premium: The Wine Industry Puzzle

    E-Print Network [OSTI]

    Delmas, Magali

    1 Eco-labeling Strategies and Price-Premium: The Wine Industry Puzzle Magali A. Delmas University with the actual label. In the context of the wine industry, we show that eco-certification leads to a price their customer about it. Frog's Leap Winery in Rutherford, 3 The OTA 2006 Manufacturer Survey Overview a

  12. Equational Termination by Semantic Labelling Hitoshi Ohsaki \\Lambda Aart Middeldorp y Jurgen Giesl z

    E-Print Network [OSTI]

    Giesl, Juergen

    Equational Termination by Semantic Labelling Hitoshi Ohsaki \\Lambda Aart Middeldorp y Jurgen Giesl z Semantic labelling (Zantema [5]) is a powerful tool for proving termination of term rewrite, parameterized by three choices: (1) the wellfounded order on the underlying algebra (partial order vs. quasi

  13. Growth or penetration of Salmonella into citrus fruit is not facilitated by natural-light labels

    E-Print Network [OSTI]

    Burns, Jacqueline K.

    and vegetables, the desired information is etched onto the produce surface using a low-energy carbon dioxide Most produce items are currently labeled with Price Look-Up (PLU) stickers that contain a four number for labeling citrus surfaces with a low energy carbon dioxide laser beam (10,600 nm; Drouillard & Rowland, 1997

  14. Nucleic acid analysis using terminal-phosphate-labeled nucleotides

    DOE Patents [OSTI]

    Korlach, Jonas (Ithaca, NY); Webb, Watt W. (Ithaca, NY); Levene, Michael (Ithaca, NY); Turner, Stephen (Ithaca, NY); Craighead, Harold G. (Ithaca, NY); Foquet, Mathieu (Ithaca, NY)

    2008-04-22

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  15. Putting Pediatric Off Label Prescribing on the Map: A Study to Understand which Children, Medications and Physicians are Involved in Prescribing Drugs for Unapproved Uses

    E-Print Network [OSTI]

    Bazzano, Alicia Theresa Francesca

    2012-01-01

    Slonim, A. D. (2007). Off-label drug use in hospitalizedassociated with off-label prescribing in primary care.P. (2006). Evaluating the off-label use of medications in

  16. EIA Energy Efficiency-Appliance Standards and Labeling Links

    U.S. Energy Information Administration (EIA) Indexed Site

    and enforcement requirements for residential appliances; final rule Energy Efficiency and Renewable Energy - Appliances & Commercial Equipment Standards, the program develops test...

  17. HAZARDOUS WASTE SATELLITE ACCUMULATION AREA REQUIREMENTS 1. Mark all waste containers conspicuously with the words "Hazardous Waste."

    E-Print Network [OSTI]

    Slatton, Clint

    HAZARDOUS WASTE SATELLITE ACCUMULATION AREA REQUIREMENTS 1. Mark all waste containers conspicuously. Decontaminate 5. Dispose of cleanup debris as Hazardous Waste Chemical Spill major 1. Evacuate area, isolate with the words "Hazardous Waste." 2. Label all containers accurately, indicating the constituents and approximate

  18. BES Science Network Requirements

    E-Print Network [OSTI]

    Dart, Eli

    2011-01-01

    the Directors of the Office of Science, Office of AdvancedOffice of Basic Energy Sciences. This is LBNL report LBNL-BES Science Network Requirements Report of the Basic Energy

  19. Selected Guidance & Requirements

    Broader source: Energy.gov [DOE]

    This page contains the most requested NEPA guidance and requirement documents and those most often recommended by the Office of NEPA Policy and Compliance. Documents are listed by agency, in...

  20. Promulgating Nuclear Safety Requirements

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1996-05-15

    Applies to all Nuclear Safety Requirements Adopted by the Department to Govern the Conduct of its Nuclear Activities. Cancels DOE P 410.1. Canceled by DOE N 251.85.

  1. Supplementary material Setting the weight cut-off in the labelling of gene families with GOslim annotation

    E-Print Network [OSTI]

    Gent, Universiteit

    Supplementary material Setting the weight cut-off in the labelling of gene families with GOslim cut-off values in the abscis. The plots show how many gene labels were appointed to the family S1 shows that if the cut-off value increases, the amount of gene families with many GOslim labels

  2. DOI 10.1007/s10994-011-5272-5 Statistical topic models for multi-label document

    E-Print Network [OSTI]

    Steyvers, Mark

    . A drawback of these approaches is that performance rapidly drops off as the total num- ber of labelsMach Learn DOI 10.1007/s10994-011-5272-5 Statistical topic models for multi-label document / Accepted: 9 November 2011 The Author(s) 2011 Abstract Machine learning approaches to multi-label document

  3. Nanodiamonds with silicon vacancy defects for non-toxic photostable fluorescent labeling of neural precursor cells

    E-Print Network [OSTI]

    Merson, Tobias D; Aharonovich, Igor; Turbic, Alisa; Kilpatrick, Trevor J; Turnley, Ann M

    2013-01-01

    Nanodiamonds (NDs) containing silicon vacancy (SiV) defects were evaluated as a potential biomarker for the labeling and fluorescent imaging of neural precursor cells (NPCs). SiV-containing NDs were synthesized using chemical vapor deposition and silicon ion implantation. Spectrally, SiV-containing NDs exhibited extremely stable fluorescence and narrow bandwidth emission with an excellent signal to noise ratio exceeding that of NDs containing nitrogen-vacancy (NV) centers. NPCs labeled with NDs exhibited normal cell viability and proliferative properties consistent with biocompatibility. We conclude that SiVcontaining NDs are a promising biomedical research tool for cellular labeling and optical imaging in stem cell research.

  4. Dispenser printing for prototyping microscale devices

    E-Print Network [OSTI]

    Wright, Paul K.; Dornfeld, David A.; Chen, Alic; Ho, Christine C.; Evans, James W.

    2010-01-01

    on the ends of MEMS cantilever sensors (Leland et al. ,White (2009). A MEMS AC current sensor for residential andMEMS piezoelectric energy harvester and a thick film micro capacitor as a power supply system for wireless sensor

  5. Room Temperature Dispenser Photocathode Using Elemental Cesium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust, High-Throughput Analysis of Protein Structures PrintRooftop DiagnosticianRoom Temperature

  6. Colorado E85 Dispensing Waiver Letter

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlenderBusiness Case for E85CaliforniaClean Citiesr

  7. E85 Fuel Dispensers Lacking UL Listing

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlenderBusiness Case for E85CaliforniaClean

  8. Enhanced detection of fluorescence quenching in labeled cells

    DOE Patents [OSTI]

    Crissman, H.A.; Steinkamp, J.A.

    1987-11-30

    A method is provided for quantifying BrdU labeled DNA in cells. The BrdU is substituted onto the DNA and the DNA is stained with a first fluorochrome having a fluorescence which is quenchable by BrdU. The first fluorochrome is preferably a thymidine base halogen analogue, such as a Hoechst fluorochrome. The DNA is then stained with a second fluorochrome having a fluorescence which is substantially uneffected by BrdU. The second fluorochrome may be selected from the group consisting of mithramycin, chromomycin A3, olivomycin, propidium iodide and ethidium bromine. The fluorescence from the first and second fluorochromes is then measured to obtain first and second output signals, respectively. The first output signal is subtracted from the second output signal to obtain a difference signal which is functionally related to the quantity of BrdU incorporated into DNA. The technique is particularly useful for quantifying the synthesis of DNA during the S-phase of the cell cycle. 2 figs.

  9. Calendar Year 2007 Program Benefits for ENERGY STAR Labeled Products

    SciTech Connect (OSTI)

    Sanchez, Marla Christine; Homan, Gregory; Brown, Richard

    2008-10-31

    ENERGY STAR is a voluntary energy efficiency-labeling program operated jointly by the United States Department of Energy and the United States Environmental Protection Agency (US EPA). Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products. ENERGY STAR's central role in the development of regional, national, and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with committed stakeholders. Through 2007, the program saved 7.1 Quads of primary energy and avoided 128 MtC equivalent. The forecast shows that the program is expected to save 21.2 Quads of primary energy and avoid 375 MtC equivalent over the period 2008-2015. The sensitivity analysis bounds the best estimate of carbon avoided between 84 MtC and 172 MtC (1993 to 2007) and between 243 MtC and 519 MtC (2008 to 2015).

  10. Field Labeling to Ensure the Electrical Safety of Production Equipment

    E-Print Network [OSTI]

    Mills, Todd

    2012-05-11

    The Occupational Safety and Health Administration (OSHA) requires that all equipment that uses electrical power be certified as electrically safe by a Nationally Recognized Testing Lab (NRTL) or Authority Having Jurisdiction (AHJ) prior to being...

  11. High School if required

    E-Print Network [OSTI]

    Walker, Lawrence R.

    ; contact Physics *CHEM 474 3 Biochemistry I *CHEM 475 3 Biochemistry II CHEM 355 & 355L 3+2 Quantitative *CHEM 447 2 Advanced Synthesis Lab *CHEM 455 & 455L 3+2 Instrumental Analysis *CHEM 472 2 Biochemistry AP 4-5 Lab required @ UNLV; contact Chemistry PHYS 182 & 182L Engineering Physics III PHYS 180 & 180L

  12. High School if required

    E-Print Network [OSTI]

    Walker, Lawrence R.

    as MATH 126 CHEM 474 3 Biochemistry I CHEM 355 & 355L 3+2 Quantitative Analysis CHEM 402 1 Scientific 182 & 182L Engineering Physics III PHYS 180 & 180L Engineering Physics I Physics C - E & M 4 required (prerequisites vary by major) *CHEM 475 3 Biochemistry II *CHEM 472 2 Biochemistry Laboratory co

  13. Modular Coil Sys Requirements

    E-Print Network [OSTI]

    Princeton Plasma Physics Laboratory

    Modular Coil Sys Requirements BSPEC140101 Conductor Specification CSPEC1420301 Winding Form Specification CSPEC1410313 Mod Coil Asm Specification CSPEC1420501 Coil TypeAB Winding Pack SE142A019R0 Coil Asm SE141058R3 Pol Break Shim Asm SE141078R2A EM/Struct Analysis of Coil and Shell CALC1400100 Mod

  14. Requirements Definition Stage

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-05-21

    This chapter addresses development of a Software Configuration Management Plan to track and control work products, analysis of the system owner/users' business processes and needs, translation of those processes and needs into formal requirements, and planning the testing activities to validate the performance of the software product.

  15. Requirements for Xenon International

    SciTech Connect (OSTI)

    Hayes, James C.; Ely, James H.

    2013-09-26

    This document defines the requirements for the new Xenon International radioxenon system. The output of this project will be a Pacific Northwest National Laboratory (PNNL) developed prototype and a manufacturer-developed production prototype. The two prototypes are intended to be as close to matching as possible; this will be facilitated by overlapping development cycles and open communication between PNNL and the manufacturer.

  16. High School if required

    E-Print Network [OSTI]

    Walker, Lawrence R.

    years... UNLV Chemistry Placement Exam Spring Sr Year MATH 95 Introductory Algebra Math Placement Testing ACT MATH 96 Intermediate Algebra Math Placement Testing ACT 20 SAT 500 MPT 12 CS to freshman year if required; MATH 127 Precalculus I Math Placement Testing ACT 25 SAT 560 MPT 26 MATH 181

  17. High School if required

    E-Print Network [OSTI]

    Walker, Lawrence R.

    years... UNLV Chemistry Placement Exam Spring Sr Year MATH 95 Introductory Algebra Math Placement Testing ACT MATH 96 Intermediate Algebra Math Placement Testing ACT 20 SAT 500 MPT 12 BIOL to freshman year if required; MATH 127 Precalculus I Math Placement Testing ACT 25 SAT 560 MPT 26 MATH 181

  18. High School if required

    E-Print Network [OSTI]

    Walker, Lawrence R.

    Spring Sr Year MATH 95 Introductory Algebra Math Placement Testing ACT MATH 96 Intermediate Algebra Math Placement Testing ACT 20 SAT 500 MPT 12 CHEM 428 3 Quantum Chemistry CHEM 431` 3 to freshman year if required; MATH 127 Precalculus I Math Placement Testing ACT 25 SAT 560 MPT 26 MATH 181

  19. High School if required

    E-Print Network [OSTI]

    Walker, Lawrence R.

    years... UNLV Chemistry Placement Exam Spring Sr Year MATH 95 Introductory Algebra Math Placement Testing ACT MATH 96 Intermediate Algebra Math Placement Testing ACT 20 SAT 500 MPT 12 to freshman year if required; MATH 127 Precalculus I Math Placement Testing ACT 25 SAT 560 MPT 26 MATH 181

  20. Requirements Career Prospects

    E-Print Network [OSTI]

    No, Reinhold

    . A doctorate demands a great deal of energy, discipline and perseverance. In Germany some 25,000 graduatesRequirements Programmes Career Prospects in Germany | 2010 #12;Editorial 3 Doing a Doctorate in Germany Publisher DAAD Deutscher Akademischer Austauschdienst German Academic Exchange Service

  1. Molecular engineering of new protein labeling methodology based on rational design and in vitro evolution

    E-Print Network [OSTI]

    Choi, Yoon-Aa

    2010-01-01

    Site-specific labeling using E coli biotin ligase (BirA) and its 15-amino acid "acceptor peptide" (AP) has been applied to study the function of various cellular proteins. In order to extend the capabilities of biotin ...

  2. A detection instrument for enhanced-fluorescence and label-free imaging on photonic

    E-Print Network [OSTI]

    Cunningham, Brian

    A detection instrument for enhanced- fluorescence and label-free imaging on photonic crystal detection of dye-tagged hybridized DNA yields 3x more genes to be detected versus commercially available

  3. The Major Role of Clinicians in the Discovery of Off-Label Drug Therapies

    E-Print Network [OSTI]

    DeMonaco, Harold J.

    2005-09-23

    Objective: To determine, through a review of the medical literature and author contact, the role of clinicians in the discovery of off label use of Food and Drug Administration approved prescription drugs.

  4. Site-specific N-terminal labeling of proteins using sortase-mediated reactions

    E-Print Network [OSTI]

    Theile, Christopher S.

    This protocol describes the use of sortase-mediated reactions to label the N terminus of any given protein of interest. The sortase recognition sequence, LPXTG (for Staphylococcus aureus sortase A) or LPXTA (for Streptococcus ...

  5. Label-free carbon nanotube sensors for glycan and protein detection

    E-Print Network [OSTI]

    Reuel, Nigel F. (Nigel Forest)

    2014-01-01

    Nanoengineered glycan sensors may help realize the long-held goal of accurate and rapid glycoprotein profiling without labeling or glycan liberation steps. Current methods of profiling oligosaccharides displayed on protein ...

  6. The Classification, Packaging and Labelling of Dangerous Substances (Amendment) Regulations 1986

    E-Print Network [OSTI]

    Her Majesty's Stationary Office

    1986-01-01

    These Regulations amend the Classification, Packagmg and Labelling of Dangcrous Substances Regulations 1984 ("the principal Regulations") to give effect with respect to Great Britain to the provisions of- (a) Commission ...

  7. Site-specific protein labeling via sortase A and its applications/

    E-Print Network [OSTI]

    Popp, Maximilian Wei-Lin

    2011-01-01

    Technological improvements in the assays and equipment used for biological, biochemical, biophysical and microscopy purposes have ensured that methods for labeling of proteins with reporter molecules remain in high demand. ...

  8. Semantic Role Labelling With Chunk Sequences Ulrike Baldewein, Katrin Erk, Sebastian Pad

    E-Print Network [OSTI]

    Semantic Role Labelling With Chunk Sequences Ulrike Baldewein, Katrin Erk, Sebastian Pad Saarland University Saarbrcken, Germany {ulrike,erk,pado}@coli.uni-sb.de Detlef Prescher University of Amsterdam

  9. Stimulating carbon efficient supply chains : carbon labels and voluntary public private partnerships

    E-Print Network [OSTI]

    Tan, Kwan Chong

    2009-01-01

    This thesis looks at the potential of labeling products with life cycle greenhouse gas emission information as a bottom-up, complementary alternative to carbon cap and trade systems. By improving the transparency of product ...

  10. Kinetic isotope effects significantly influence intracellular metabolite [superscript 13]C labeling patterns and flux determination

    E-Print Network [OSTI]

    Stephanopoulos, Gregory

    Rigorous mathematical modeling of carbon-labeling experiments allows estimation of fluxes through the pathways of central carbon metabolism, yielding powerful information for basic scientific studies as well as for a wide ...

  11. Whispering Gallery Mode Resonators for Rapid Label-Free Biosensing in Small Volume Droplets

    E-Print Network [OSTI]

    Wildgen, Sarah M.; Dunn, Robert C.

    2015-03-23

    WGM resonators as label-free sensors in 10 ?L sample droplets. Droplet evaporation leads to potentially useful convective mixing, but also limits the time over which analysis can be completed. We show that active droplet mixing combined with initial...

  12. Finding Patterns in Behavioral Observations by Automatically Labeling Forms of Wikiwork in Barnstars

    E-Print Network [OSTI]

    McDonald, David W.

    Finding Patterns in Behavioral Observations by Automatically Labeling Forms of Wikiwork everyday behavioral observations to develop tools that could improve understanding and sense making behavioral observations; observations that people make of those around them. In a large online community

  13. Economic impact of country-of-origin labeling in the U.S. beef industry

    E-Print Network [OSTI]

    Hanselka, Daniel David

    2006-04-12

    Concerns over the total costs assessed to the beef industry from the implementation of mandatory country-of-origin labeling (COOL) regulations warranted an investigation into the estimation and distribution of marketing ...

  14. Label-free route to rapid, nanoscale characterization of cellular structure and dynamics through opaque media

    E-Print Network [OSTI]

    Joshi, Bipin

    We report a novel technique for label-free, rapid visualization of structure and dynamics of live cells with nanoscale sensitivity through traditionally opaque media. Specifically, by combining principles of near-infrared ...

  15. An Investigation on Gel Electrophoresis with Quantum Dots End-labeled DNA

    E-Print Network [OSTI]

    Chen, Xiaojia

    2009-05-15

    explored manipulating DNA fragments by end labeling DNA molecules with quantum dot nanocrystals. The quantum dot-DNA conjugates can be further modified through binding interactions with biotinylated single-stranded DNA primers. Single molecule visualization...

  16. Generating Fo contours from ToBI labels using linear regression

    E-Print Network [OSTI]

    Black, Alan W; Hunt, Andrew

    This paper describes a method for generating F0 contours from ToBI labelled utterances. The method uses linear regression to predict F0 target values for the start, mid-vowel and end of every syllable, using features ...

  17. Synthesis of isotopically labeled R- or S-[.sup.13C, .sup.2H] glycerols

    SciTech Connect (OSTI)

    Martinez, Rodolfo A.; Unkefer, Clifford J.; Alvarez, Marc A.

    2008-01-22

    The present invention is directed to asymmetric chiral labeled glycerols including at least one chiral atom, from one to two .sup.13C atoms and from zero to four deuterium atoms bonded directly to a carbon atom, e.g., (2S) [1,2-.sup.13C.sub.2]glycerol and (2R) [1,2-.sup.13C.sub.2]glycerol, and to the use of such chiral glycerols in the preparation of labeled amino acids.

  18. Method for rapid base sequencing in DNA and RNA with two base labeling

    DOE Patents [OSTI]

    Jett, James H. (Los Alamos, NM); Keller, Richard A. (Los Alamos, NM); Martin, John C. (Los Alamos, NM); Posner, Richard G. (Los Alamos, NM); Marrone, Babetta L. (Los Alamos, NM); Hammond, Mark L. (Los Alamos, NM); Simpson, Daniel J. (Los Alamos, NM)

    1995-01-01

    Method for rapid-base sequencing in DNA and RNA with two-base labeling and employing fluorescent detection of single molecules at two wavelengths. Bases modified to accept fluorescent labels are used to replicate a single DNA or RNA strand to be sequenced. The bases are then sequentially cleaved from the replicated strand, excited with a chosen spectrum of electromagnetic radiation, and the fluorescence from individual, tagged bases detected in the order of cleavage from the strand.

  19. Method for rapid base sequencing in DNA and RNA with two base labeling

    DOE Patents [OSTI]

    Jett, J.H.; Keller, R.A.; Martin, J.C.; Posner, R.G.; Marrone, B.L.; Hammond, M.L.; Simpson, D.J.

    1995-04-11

    A method is described for rapid-base sequencing in DNA and RNA with two-base labeling and employing fluorescent detection of single molecules at two wavelengths. Bases modified to accept fluorescent labels are used to replicate a single DNA or RNA strand to be sequenced. The bases are then sequentially cleaved from the replicated strand, excited with a chosen spectrum of electromagnetic radiation, and the fluorescence from individual, tagged bases detected in the order of cleavage from the strand. 4 figures.

  20. Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

    DOE Patents [OSTI]

    Glazer, A.N.; Mathies, R.A.; Hung, S.C.; Ju, J.

    1998-12-29

    Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures. 22 figs.

  1. Glass transition and alpha-relaxation dynamics of thin films of labeled polystyrene

    E-Print Network [OSTI]

    Rodney D. Priestley; Linda J. Broadbelt; John M. Torkelson; Koji Fukao

    2008-01-05

    The glass transition temperature and relaxation dynamics of the segmental motions of thin films of polystyrene labeled with a dye, 4-[N-ethyl-N-(hydroxyethyl)]amino-4-nitraozobenzene (Disperse Red 1, DR1) are investigated using dielectric measurements. The dielectric relaxation strength of the DR1-labeled polystyrene is approximately 65 times larger than that of the unlabeled polystyrene above the glass transition, while there is almost no difference between them below the glass transition. The glass transition temperature of the DR1-labeled polystyrene can be determined as a crossover temperature at which the temperature coefficient of the electric capacitance changes from the value of the glassy state to that of the liquid state. The glass transition temperature of the DR1-labeled polystyrene decreases with decreasing film thickness in a reasonably similar manner to that of the unlabeled polystyrene thin films. The dielectric relaxation spectrum of the DR1-labeled polystyrene is also investigated. As thickness decreases, the $\\alpha$-relaxation time becomes smaller and the distribution of the $\\alpha$-relaxation times becomes broader. These results show that thin films of DR1-labeled polystyrene are a suitable system for investigating confinement effects of the glass transition dynamics using dielectric relaxation spectroscopy.

  2. Required Information Release Stephen Chong

    E-Print Network [OSTI]

    Chong, Stephen

    Required Information Release Stephen Chong School of Engineering and Applied Sciences Harvard re- quirement to release information. Such requirements are an important part of a system's information security requirements. Current information-flow control techniques are able to reason about

  3. BIOMEDICAL ENGINEERING BSE PLAN REQUIREMENTS Campus: UMICH RG = Requirement Group

    E-Print Network [OSTI]

    Cafarella, Michael J.

    BIOMEDICAL ENGINEERING BSE PLAN REQUIREMENTS Campus: UMICH RG = Requirement Group Career: UENG RQ = Requirement Program: LN = Line Plan: 0880BSE Sub-Plan: RG 6856 BIOMEDICAL ENGINEERING MAJOR REQUIREMENTS Effective FA05/1560 (09/06/2005) RQ 4996 Program Subjects Effective FA05/1560 (09/06/2005) LN 0010 BIOMEDE

  4. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2003-12-09

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4, ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  5. Compositions for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R. (Agoura Hills, CA); Petric, Andrej (Ljubljana, SI); Satyamurthy, Nagichettiar (Los Angeles, CA); Small, Gary W. (Los Angeles, CA); Cole, Gregory M. (Santa Monica, CA); Huang, Sung-Cheng (Sherman Oaks, CA)

    2008-03-11

    Compositions useful for labeling .beta.-amyloid plaques and neurofibrillary tangles are provided. The compositions comprises compounds of formula (I): ##STR00001## wherein R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2-alkyl, --C.dbd.C(CN).sub.2-alkylenyl-R.sub.4, ##STR00002## wherein R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 and --C(O)NH.sub.2; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S; and R.sub.2 is selected from the group consisting of alkyl and alkylenyl-R.sub.10 and R.sub.3 is alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal, and spiperone-3-yl, or R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl, and further wherein one or more of the hydrogen, halogen or carbon atoms are optionally replaced with a radiolabel.

  6. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R. (Agoura Hills, CA); Petric, Andrej (Ljubljana, SI); Satyamurthy, Nagichettiar (Los Angeles, CA); Small, Gary W. (Los Angeles, CA); Cole, Gregory M. (Santa Monica, CA); Huang, Sung-Cheng (Sherman Oaks, CA)

    2001-01-01

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4 , ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5, is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH , --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  7. BES Science Network Requirements

    SciTech Connect (OSTI)

    Biocca, Alan; Carlson, Rich; Chen, Jackie; Cotter, Steve; Tierney, Brian; Dattoria, Vince; Davenport, Jim; Gaenko, Alexander; Kent, Paul; Lamm, Monica; Miller, Stephen; Mundy, Chris; Ndousse, Thomas; Pederson, Mark; Perazzo, Amedeo; Popescu, Razvan; Rouson, Damian; Sekine, Yukiko; Sumpter, Bobby; Dart, Eli; Wang, Cai-Zhuang -Z; Whitelam, Steve; Zurawski, Jason

    2011-02-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivityfor the US Department of Energy Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of the Office ofScience programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years.

  8. BER Science Network Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAudits & Inspections Audits &driversNetwork Requirements Report of the

  9. ENGINEERING PHYSICS BSE Plan Requirements

    E-Print Network [OSTI]

    Cafarella, Michael J.

    ENGINEERING PHYSICS BSE Plan Requirements 1 Campus: UMICH RG = Requirement Group Career: UENG RQ = Requirement Program: LN = Line Plan: 2990BSE RG 6394 ENGINEERING PHYSICS MAJOR REQUIREMENTS Effective FA12/1910 (09/04/2012) RQ 4925 Physics Technical Subjects (C or higher) Effective FA12/1910 (09/04/2012) LN 0010

  10. TABLE OF CONTENTS Accident Prevention Signs, Tags, Labels, Signals,

    E-Print Network [OSTI]

    US Army Corps of Engineers

    to meet or exceed ANSI and/or OSHA requirements. USACE facilities shall use signs based upon and contractors may opt to use signs meeting either the OSHA or ANSI standards for temporary use during the life.200; Accident Prevention Signs and Tags; e. ANSI/IEEE C95.2; f. ANSI Z136.1; g. ANSI Z535.1; h. ANSI Z535.2; i

  11. Equipment Operational Requirements

    SciTech Connect (OSTI)

    Greenwalt, B; Henderer, B; Hibbard, W; Mercer, M

    2009-06-11

    The Iraq Department of Border Enforcement is rich in personnel, but poor in equipment. An effective border control system must include detection, discrimination, decision, tracking and interdiction, capture, identification, and disposition. An equipment solution that addresses only a part of this will not succeed, likewise equipment by itself is not the answer without considering the personnel and how they would employ the equipment. The solution should take advantage of the existing in-place system and address all of the critical functions. The solutions are envisioned as being implemented in a phased manner, where Solution 1 is followed by Solution 2 and eventually by Solution 3. This allows adequate time for training and gaining operational experience for successively more complex equipment. Detailed descriptions of the components follow the solution descriptions. Solution 1 - This solution is based on changes to CONOPs, and does not have a technology component. It consists of observers at the forts and annexes, forward patrols along the swamp edge, in depth patrols approximately 10 kilometers inland from the swamp, and checkpoints on major roads. Solution 2 - This solution adds a ground sensor array to the Solution 1 system. Solution 3 - This solution is based around installing a radar/video camera system on each fort. It employs the CONOPS from Solution 1, but uses minimal ground sensors deployed only in areas with poor radar/video camera coverage (such as canals and streams shielded by vegetation), or by roads covered by radar but outside the range of the radar associated cameras. This document provides broad operational requirements for major equipment components along with sufficient operational details to allow the technical community to identify potential hardware candidates. Continuing analysis will develop quantities required and more detailed tactics, techniques, and procedures.

  12. Microfluidic Technology Platforms for Synthesizing, Labeling and Measuring the Kinetics of Transport and Biochemical Reactions for Developing Molecular Imaging Probes

    SciTech Connect (OSTI)

    Phelps, Michael E.

    2009-09-01

    Radiotracer techniques are used in environmental sciences, geology, biology and medicine. Radiotracers with Positron Emission Tomography (PET) provided biological examinations of ~3 million patients 2008. Despite the success of positron labeled tracers in many sciences, there is limited access in an affordable and convenient manner to develop and use new tracers. Integrated microfluidic chips are a new technology well matched to the concentrations of tracers. Our goal is to develop microfluidic chips and new synthesis approaches to enable wide dissemination of diverse types of tracers at low cost, and to produce new generations of radiochemists for which there are many unfilled jobs. The program objectives are to: 1. Develop an integrated microfluidic platform technology for synthesizing and 18F-labeling diverse arrays of different classes of molecules. 2. Incorporate microfluidic chips into small PC controlled devices (Synthesizer) with a platform interfaced to PC for electronic and fluid input/out control. 3. Establish a de-centralized model with Synthesizers for discovering and producing molecular imaging probes, only requiring delivery of inexpensive [18F]fluoride ion from commercial PET radiopharmacies vs the centralized approach of cyclotron facilities synthesizing and shipping a few different types of 18F-probes. 4. Develop a position sensitive avalanche photo diode (PSAPD) camera for beta particles embedded in a microfluidic chip for imaging and measuring transport and biochemical reaction rates to valid new 18F-labeled probes in an array of cell cultures. These objectives are met within a research and educational program integrating radio-chemistry, synthetic chemistry, biochemistry, engineering and biology in the Crump Institute for Molecular Imaging. The Radiochemistry Training Program exposes PhD and post doctoral students to molecular imaging in vitro in cells and microorganisms in microfluidic chips and in vivo with PET, from new technologies for radiochemistry (macro to micro levels), biochemistry and biology to imaging principles, tracer kinetics, pharmacokinetics and biochemical assays. New generations of radiochemists will be immersed in the biochemistry and biology for which their labeled probes are being developed for assays of these processes. In this program engineers and radio-chemists integrate the principles of microfluidics and radiolabeling along with proper system design and chemistry rule sets to yield Synthesizers enabling biological and pharmaceutical scientists to develop diverse arrays of probes to pursue their interests. This progression would allow also radiochemists to focus on the further evolution of rapid, high yield synthetic reactions with new enabling technologies, rather than everyday production of radiotracers that should be done by technologists. The invention of integrated circuits in electronics established a platform technology that allowed an evolution of ideas and applications far beyond what could have been imagined at the beginning. Rather than provide a technology for the solution to a single problem, it is hoped that microfluidic radiochemistry will be an enabling platform technology for others to solve many problems. As part of this objective, another program goal is to commercialize the technologies that come from this work so that they can be provided to others who wish to use it.

  13. ASCR Science Network Requirements

    SciTech Connect (OSTI)

    Dart, Eli; Tierney, Brian

    2009-08-24

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the US Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In April 2009 ESnet and the Office of Advanced Scientific Computing Research (ASCR), of the DOE Office of Science, organized a workshop to characterize the networking requirements of the programs funded by ASCR. The ASCR facilities anticipate significant increases in wide area bandwidth utilization, driven largely by the increased capabilities of computational resources and the wide scope of collaboration that is a hallmark of modern science. Many scientists move data sets between facilities for analysis, and in some cases (for example the Earth System Grid and the Open Science Grid), data distribution is an essential component of the use of ASCR facilities by scientists. Due to the projected growth in wide area data transfer needs, the ASCR supercomputer centers all expect to deploy and use 100 Gigabit per second networking technology for wide area connectivity as soon as that deployment is financially feasible. In addition to the network connectivity that ESnet provides, the ESnet Collaboration Services (ECS) are critical to several science communities. ESnet identity and trust services, such as the DOEGrids certificate authority, are widely used both by the supercomputer centers and by collaborations such as Open Science Grid (OSG) and the Earth System Grid (ESG). Ease of use is a key determinant of the scientific utility of network-based services. Therefore, a key enabling aspect for scientists beneficial use of high performance networks is a consistent, widely deployed, well-maintained toolset that is optimized for wide area, high-speed data transfer (e.g. GridFTP) that allows scientists to easily utilize the services and capabilities that the network provides. Network test and measurement is an important part of ensuring that these tools and network services are functioning correctly. One example of a tool in this area is the recently developed perfSONAR, which has already shown its usefulness in fault diagnosis during the recent deployment of high-performance data movers at NERSC and ORNL. On the other hand, it is clear that there is significant work to be done in the area of authentication and access control - there are currently compatibility problems and differing requirements between the authentication systems in use at different facilities, and the policies and mechanisms in use at different facilities are sometimes in conflict. Finally, long-term software maintenance was of concern for many attendees. Scientists rely heavily on a large deployed base of software that does not have secure programmatic funding. Software packages for which this is true include data transfer tools such as GridFTP as well as identity management and other software infrastructure that forms a critical part of the Open Science Grid and the Earth System Grid.

  14. Vanderbilt University Medical Center -Eye Wash Requirements Requirements

    E-Print Network [OSTI]

    Wikswo, John

    Requirements OSHA Refers to the ANSI Standard ANSI is the American National Standards Institute. ANSI Z358 University Medical Center - Eye Wash Requirements General Information from ANSI Eyewash station ANSI 9 of 15 Vanderbi

  15. ENVIRONMENTAL ENGINEERING BSE PLAN REQUIREMENTS Campus: UMICH RG = Requirement Group

    E-Print Network [OSTI]

    Cafarella, Michael J.

    ENVIRONMENTAL ENGINEERING BSE PLAN REQUIREMENTS Campus: UMICH RG = Requirement Group Career: UENG RQ = Requirement Program: LN = Line Plan: 3170BSE Sub-Plan: RG 10370 ENVIRONMENTAL ENGINEERING MAJOR LN 0020 CEE 481 or 581 LN 0030 CEE 482 or 582 RQ 6790 Environmental Engineering Design Effective FA12

  16. UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL UTILITIES REQUIREMENTS

    E-Print Network [OSTI]

    Arnold, Jonathan

    UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL UTILITIES REQUIREMENTS JANUARY 16, 2015 33 00 001 33 00 00 GENERAL UTILITIES REQUIREMENTS 1. GENERAL A. Related sections: i. 01 41 26.02 Utility Information & Locate ii. 23 05 19 Meters and Gages iii

  17. Energy-efficiency labels and standards: A guidebook for appliances, equipment and lighting

    SciTech Connect (OSTI)

    McMahon, James E.; Wiel, Stephen

    2001-02-16

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and the United Nations Foundation (UNF) recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labeling programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This guidebook was prepared over the course of the past year with significant contribution from the authors and reviewers mentioned previously. Their diligent participation has made this the international guidance tool it was intended to be. The lead authors would also like to thank the following individuals for their support in the development, production, and distribution of the guidebook: Marcy Beck, Elisa Derby, Diana Dhunke, Ted Gartner, and Julie Osborn of Lawrence Berkeley National Laboratory as well as Anthony Ma of Bevilacqua-Knight, Inc. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards-setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development, implementation, maintenance, and evaluation of the programs and on the design of the labels and standards themselves. In addition, it directs the reader to references and other resources likely to be useful in conducting the activities described and includes a chapter on energy policies and programs that complement appliance efficiency labels and standards. This guidebook attempts to reflect the essential framework of labeling and standards programs. It is the intent of the authors and sponsors to distribute copies of this book worldwide at no charge for the general public benefit. The guidebook is also available on the web at www.CLASPonline.org and can be downloaded to be used intact or piecemeal for whatever beneficial purposes readers may conceive.

  18. Webinar: Hydrogen Storage Materials Requirements

    Broader source: Energy.gov [DOE]

    Video recording and text version of the webinar titled, Hydrogen Storage Materials Requirements, originally presented on June 25, 2013.

  19. Thesis and Dissertation Required Elements

    E-Print Network [OSTI]

    Texas at Arlington, University of

    Thesis and Dissertation Required Elements 2012 version UT Arlington Graduate Students Required Elements for Theses/Dissertations Thesis/dissertation documents must be written in the proper format in order to be accepted by the Office of Graduate Studies. These requirements ensure that all thesis

  20. Software and House Requirements Engineering

    E-Print Network [OSTI]

    Berry, Daniel M.

    Software and House Requirements Engineering: Lessons Learned in Combatting Requirements Creep a requirements engineer who puts her knowledge of software construction together with her creativity to come up or remodeled a house and has developed or enhanced software must have noticed the similarity

  1. Requirement Handbook for Graduate Programs

    E-Print Network [OSTI]

    Thompson, Michael

    Requirement Handbook for Graduate Programs The Department of English & Cultural Studies September 2014 August 2015 Requirement Handbook for Graduate Programs The Department of English & Cultural of English & Cultural Studies Requirement Handbook 1 | P a g e M.A. IN CULTURAL STUDIES AND CRITICAL THEORY 1

  2. In Computer Vision and Pattern Recognition (CVPR), San Francisco, June 2010 1 Fast Approximate Energy Minimization with Label Costs

    E-Print Network [OSTI]

    Toronto, University of

    Energy Minimization with Label Costs Andrew Delong* Anton Osokin Hossam N. Isack* Yuri Boykov : fp = l 0 otherwise. Energy (1) balances data costs against label costs in a formulation equivalent in computer vision due to its generality, effectiveness, and speed. Thus far it can only minimize energies

  3. Hazard Labeling Elements 1. Product identifier: how the hazardous chemical is identified. This can be (but is not

    E-Print Network [OSTI]

    Chapman, Michael S.

    Hazard Labeling Elements 1. Product identifier: how the hazardous chemical is identified. This can of severity of hazard and alert the reader to a potential hazard on the label. There are only two signal words, "Danger" and "Warning." Within a specific hazard class, "Danger" is used for the more severe hazards

  4. SUN3D: A Database of Big Spaces Reconstructed using SfM and Object Labels Jianxiong Xiao

    E-Print Network [OSTI]

    Xiao, Jianxiong

    SUN3D: A Database of Big Spaces Reconstructed using SfM and Object Labels Jianxiong Xiao Princeton introduce SUN3D, a large-scale RGB-D video database with camera pose and object labels, capturing the full 3- rameterized by its rotation and translation. The SUN3D database, the source code for the generalized bundle

  5. Integrable perturbed magnetic fields in toroidal geometry: An exact analytical flux surface label for large aspect ratio

    E-Print Network [OSTI]

    Isliker, Heinz

    Integrable perturbed magnetic fields in toroidal geometry: An exact analytical flux surface label, 056114 (2012); 10.1063/1.3694842 Driving toroidally asymmetric current through the tokamak scrape-off in toroidal geometry: An exact analytical flux surface label for large aspect ratio N. Kallinikos, H. Isliker

  6. Early Detection of Oleic Acid-Induced Lung Injury in Rats Using 111In-Labeled Anti-Rat

    E-Print Network [OSTI]

    Terasaki, Mark

    Early Detection of Oleic Acid-Induced Lung Injury in Rats Using 111In-Labeled Anti of Radiology, VA Medical Center, Newington, Connecticut Previous study of the bleomycin-induced lung injury of 111In-aICAM-1 to detect inflammation in another ARDS lung injury model. Methods: 111In-labeled rat

  7. Effects of Labels on Perception and its Relation to Visual Working Memory, Implicit Beliefs, and Metacognitive Ability

    E-Print Network [OSTI]

    Hahn, Amanda 1989-

    2011-04-21

    Labels hold a great amount of information and power, and they have been shown to affect perception and people?s decisions when making categorical and similarity judgments. This study examines why reliance on labels found in previous studies is so...

  8. Feasibility of an appliance energy testing and labeling program for Sri Lanka

    SciTech Connect (OSTI)

    Biermayer, Peter; Busch, John; Hakim, Sajid; Turiel, Issac; du Pont, Peter; Stone, Chris

    2000-04-01

    A feasibility study evaluated the costs and benefits of establishing a program for testing, labeling and setting minimum efficiency standards for appliances and lighting in Sri Lanka. The feasibility study included: refrigerators, air-conditioners, flourescent lighting (ballasts & CFls), ceiling fans, motors, and televisions.

  9. Crowdsourcing Multi-Label Classification Jonathan Bragg Mausam Daniel S. Weld

    E-Print Network [OSTI]

    Mausam

    Crowdsourcing Multi-Label Classification Jonathan Bragg Mausam Daniel S. Weld Department of Computer Science and Engineering University of Washington Seattle, WA 98195 {jbragg, mausam, weld summarizes (Bragg, Mausam, and Weld 2013), to appear at HCOMP 2013. References Bragg, J.; Mausam; and Weld, D

  10. Carbon-13 Labeled Polymers: An Alternative Tracer for Depth Profiling of Polymer Films and

    E-Print Network [OSTI]

    Carbon-13 Labeled Polymers: An Alternative Tracer for Depth Profiling of Polymer Films profiling of polymer films and multilayers using secondary ion mass spectrometry (SIMS). Deuterium substitution has traditionally been used in depth profiling of polymers but can affect the phase behavior

  11. Effective Graph Classification Based on Topological and Label Attributes , Murat Semerci2

    E-Print Network [OSTI]

    Zaki, Mohammed Javeed

    online 12 June 2012 in Wiley Online Library (wileyonlinelibrary.com). Abstract: Graph classificationEffective Graph Classification Based on Topological and Label Attributes Geng Li1 , Murat Semerci2 propose an alternative approach to graph classification that is based on feature vectors constructed from

  12. Representing Genetic Networks as Labeled Hybrid Petri Nets for State Space Exploration and Markov Chain Analysis

    E-Print Network [OSTI]

    Myers, Chris J.

    Representing Genetic Networks as Labeled Hybrid Petri Nets for State Space Exploration and Markov is to develop a way to convert genetic networks into logical models. Once this is done, finding the state graph into the reachability of the states in the original network. Therefore, the second goal of this project is to develop

  13. Kit for the selective labeling of red blood cells in whole blood with [sup 99]Tc

    DOE Patents [OSTI]

    Srivastava, S.C.; Babich, J.W.; Straub, R.; Richards, P.

    1992-05-26

    Disclosed herein are a method and kit for the preparation of [sup 99m]Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available therein for reduction of technetium. No Drawings

  14. Failure Analysis for Composition of Web Services Represented as Labeled Transition

    E-Print Network [OSTI]

    Lutz, Robyn R.

    Failure Analysis for Composition of Web Services Represented as Labeled Transition Systems Dinanath, Ames, IA 50011, USA {yogesh, sbasu, honavar, rlutz}@cs.iastate.edu Abstract. The Web service a simple e-Library Web service in the context of the MoSCoE Web service composition framework. 1

  15. Detection of atomic spin labels in a lipid bilayer using a single-spin nanodiamond probe

    E-Print Network [OSTI]

    Scholten, Robert

    Detection of atomic spin labels in a lipid bilayer using a single-spin nanodiamond probe Stefan conditions using a single-spin nanodiamond sensor. Changes in the spin relaxation time of the sensor located in a nanodiamondwhich is situated in the target structure itself and acts as a nanoscopic magnetic field detector

  16. Label-free bacteria detection using evanescent mode of a suspended core terahertz fiber

    E-Print Network [OSTI]

    Skorobogatiy, Maksim

    Label-free bacteria detection using evanescent mode of a suspended core terahertz fiber Anna time an E. coli bacteria sensor based on the evanescent field of the fundamental mode of a suspended\\ SKDJHV DQG WKHQ GHVWUR\\HG ZLWK a P-size fragments remaining bound to the fiber surface. The bacteria

  17. New method for the selective labeling of erythrocytes in whole blood with Tc-99m

    DOE Patents [OSTI]

    Srivastava, S.C.; Babich, J.W.; Straub, R.; Richards, P.

    1984-01-27

    Method and kit are described for the preparation of /sup 99m/Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available therein for the reduction of technetium.

  18. Proteinprotein interactions as a tool for site-specific labeling of proteins

    E-Print Network [OSTI]

    Michalet, Xavier

    Proteinprotein interactions as a tool for site-specific labeling of proteins MARCUS JA GER,1 the conjugation of fluorophores to proteins in a site-specific and thermodynamically nonperturbative fashion BPN0 complex as an example, we demonstrate that proteinprotein interactions can be exploited

  19. Labeling Proteins with Small Molecules by Site-Specific Posttranslational Modification

    E-Print Network [OSTI]

    Yin, Jun

    Labeling Proteins with Small Molecules by Site-Specific Posttranslational Modification Jun Yin, Fei of proteins with small synthetic molecules has been an important approach for the elucidation of protein probes into proteins allows the detection of protein conformational dynamics and the real-time tracking

  20. 2/15/05 Page 1 A Structural Diffusion Approach to Labeling Rows and

    E-Print Network [OSTI]

    Salamon, Peter

    digitized images of an array of tissue sections mounted on a microscope slide is discussed. Keywords: Medical Imaging, Computational Intelligence Running Title: Labeling Rows and Columns in an Irregular Array and the series of slides is subjected to a battery of treatments. The sheer volume of data generated

  1. 11/17/01 Page 1 A Structural Diffusion Approach to Labeling Rows and

    E-Print Network [OSTI]

    Salamon, Peter

    digitized images of an array of tissue sections mounted on a microscope slide is discussed. Keywords: Medical Imaging, Computational Intelligence Running Title: Labeling Rows and Columns in an Irregular Array and the series of slides is subjected to a battery of treatments. The sheer volume of data generated

  2. Using phylogenetic probes for quantification of stable isotope labeling and microbial community analysis

    DOE Patents [OSTI]

    Brodie, Eoin L; DeSantis, Todd Z; Karaoz, Ulas; Andersen, Gary L

    2014-12-09

    Herein is described methods for a high-sensitivity means to measure the incorporation of stable isotope labeled substrates into RNA following stable isotope probing experiments (SIP). RNA is hybridized to a set of probes such as phylogenetic microarrays and isotope incorporation is quantified such as by secondary ion mass spectrometer imaging (NanoSIMS).

  3. The ENERGY STAR Plant Label: A Valuable Component of Strategic Corporate Energy Management

    E-Print Network [OSTI]

    Tunnessen, W.

    2008-01-01

    by awarding the first ENERGY STAR labels to plants that had demonstrated energy performance in the top quartile of energy efficiency using a sector-specific energy benchmarking and rating tool. Currently, four plant types are eligible to earn the ENERGY STAR...

  4. Evolution of Graphene Growth on Ni and Cu by Carbon Isotope Labeling

    E-Print Network [OSTI]

    and acceptance by the semiconductor industry, Ni and Cu have received the most attention as a graphene substrateEvolution of Graphene Growth on Ni and Cu by Carbon Isotope Labeling Xuesong Li, Weiwei Cai, Luigi Instruments Incorporated, Dallas, Texas 75243 Received August 3, 2009 ABSTRACT Large-area graphene growth

  5. Silicon Photonic Crystal Microcavity Biosensors for Label Free Highly Sensitive and Specific Lung Cancer Detection

    E-Print Network [OSTI]

    Chen, Ray

    Silicon Photonic Crystal Microcavity Biosensors for Label Free Highly Sensitive and Specific Lung detect lung cancer cell lysates with high sensitivity down to 2 cells per microliter with silicon based detection of control experiment to verify specificity again. Primary lung cancer develops from epithelial

  6. Transforming Termination by SelfLabelling Aart Middeldorp, 1 Hitoshi Ohsaki, 1 Hans Zantema 2

    E-Print Network [OSTI]

    Utrecht, Universiteit

    Transforming Termination by Self­Labelling Aart Middeldorp, 1 Hitoshi Ohsaki, 1 Hans Zantema 2 1 introduce a new technique for proving termination of term rewriting systems. The technique, a specialization of transformation methods that attempt to prove termination by transforming term rewriting systems into systems

  7. Transforming Termination by Self-Labelling Aart Middeldorp,1 Hitoshi Ohsaki,1 Hans Zantema2

    E-Print Network [OSTI]

    Utrecht, Universiteit

    Transforming Termination by Self-Labelling Aart Middeldorp,1 Hitoshi Ohsaki,1 Hans Zantema2 1 introduce a new technique for proving termination of term rewriting systems. The technique, a specialization of transformation methods that attempt to prove termination by transforming term rewriting systems into systems

  8. Optical Networks Magazine May/June 2003 17 Optical-label

    E-Print Network [OSTI]

    Kolner, Brian H.

    Optical Networks Magazine May/June 2003 17 Optical-label switching, MPLS, MPLambdaS, and GMPLS S. J impressive progress accelerated by new enabling technologies such as optical fiber amplifiers. A number of commercial optical networking systems were announced and their deployments took place rapidly in the late 90

  9. Lesson Summary Students draw and label the parts of the Sun that

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    Lesson Summary Students draw and label the parts of the Sun that they are familiar with. Next understanding of the Sun's features. Prior Knowledge & Skills Completed the lesson: The Dynamic Nature of the Sun Understanding of: The Sun as a dynamic object The basic structure and function of the Sun

  10. Label Structured Cell Proliferation Models H. T. Banks, Frederique Charles, Marie Doumic Jauffret,

    E-Print Network [OSTI]

    proliferation and death rates, respectively, relative to the moving label coordinate system + . Daughter cells for Quantitative Sciences in Biomedicine North Carolina State University Raleigh, NC 27695-8213 and INRIA-Activated Cell Sorter (FACS) recorded) CFSE fluores- cence intensity (FI) (in units of log intensity, log UI

  11. Joint Inference of Multiple Label Types in Large Networks Deepayan Chakrabarti DEEPAY@FB.COM

    E-Print Network [OSTI]

    @FB.COM Stanislav Funiak SFUNIAK@FB.COM Jonathan Chang JONCHANG@FB.COM Sofus A. Macskassy SOFMAC@FB.COM Facebook Inc-passing architecture. On a billion-node subset of the Facebook social network, EDGEEXPLAIN signif- icantly outperforms the group from u's actual current city C, causing label propagation to infer C for u. However, our proposed

  12. Spine Detection and Labeling Using a Parts-Based Graphical Model

    E-Print Network [OSTI]

    Schnrr, Christoph

    for automatically locating the human vertebral column (spine) and for simultaneously labeling the inter- vertebral) for localizing the spine column and individual vertebrae. Integration of spatial context is essential, however sound model for reliably detecting and localizing the spine column, that copes with the complexity

  13. Context Sensitive Labeling of Spinal Structure in MR Images Chetan Bholea, Suryaprakash Kompallib and Vipin Chaudharyb

    E-Print Network [OSTI]

    Chaudhary, Vipin

    of structures in the vertebral column have similar imaging properties; the disks, spinal cord, and vertebrae of them aim at classification of the entire vertebral column while we concentrate only on the lumbar information from T1W sagittal, T2W sagittal and T2W axial MR images to automatically label disks and vertebral

  14. Resolution in Support of Customer "Right-to-Know" and Product Labeling

    E-Print Network [OSTI]

    of such disclosure is clearly established in nutrition labeling, uniform food pricing, truth-in-lending and many calling for new proposals to preserve environmental and diversity benefits in a more competitive and to preserve renewable resources, resource diversity and environmental protection; now, therefore

  15. Making the Most of Using Depth Reasoning to Label Line Drawings of Engineering Objects

    E-Print Network [OSTI]

    Martin, Ralph R.

    the automated production of solid models from line drawings which show the visible edges of polyhedral objectsMaking the Most of Using Depth Reasoning to Label Line Drawings of Engineering Objects P. A. C freehand sketches would benefit designers. A subgoal is to take a single line drawing (with hidden lines

  16. Putting Pediatric Off Label Prescribing on the Map: A Study to Understand which Children, Medications and Physicians are Involved in Prescribing Drugs for Unapproved Uses

    E-Print Network [OSTI]

    Bazzano, Alicia Theresa Francesca

    2012-01-01

    A. D. (2007). Off-label drug use in hospitalized children.J. A. , & Tamblyn, R. (2012). Drug, patient, and physician2002). Off-label use of drugs in Italy: A prospective,

  17. Managing System of Systems Requirements with a Requirements Screening Group

    SciTech Connect (OSTI)

    Ronald R. Barden

    2012-07-01

    Figuring out an effective and efficient way to manage not only your Requirements Baseline, but also the development of all your individual requirements during a Programs/Projects Conceptual and Development Life Cycle Stages can be both daunting and difficult. This is especially so when you are dealing with a complex and large System of Systems (SoS) Program with potentially thousands and thousands of Top Level Requirements as well as an equal number of lower level System, Subsystem and Configuration Item requirements that need to be managed. This task is made even more overwhelming when you have to add in integration with multiple requirements development teams (e.g., Integrated Product Development Teams (IPTs)) and/or numerous System/Subsystem Design Teams. One solution for tackling this difficult activity on a recent large System of Systems Program was to develop and make use of a Requirements Screening Group (RSG). This group is essentially a Team made up of co-chairs from the various Stakeholders with an interest in the Program of record that are enabled and accountable for Requirements Development on the Program/Project. The RSG co-chairs, often with the help of individual support team, work together as a Program Board to monitor, make decisions on, and provide guidance on all Requirements Development activities during the Conceptual and Development Life Cycle Stages of a Program/Project. In addition, the RSG can establish and maintain the Requirements Baseline, monitor and enforce requirements traceability across the entire Program, and work with other elements of the Program/Project to ensure integration and coordination.

  18. INFORMS Journal on Computing, Vol. 9, No. 3, Summer 1997, pp. 266-275. Placing Text Labels on Maps and Diagrams

    E-Print Network [OSTI]

    Wainwright, Roger L.

    The University of Tulsa 600 South College Avenue Tulsa, OK 74104-3189, USA Abstract Cartographic label placement

  19. Just: Data requirements Data requirements of reverse-engineering algorithms

    E-Print Network [OSTI]

    Just, Winfried

    Just: Data requirements Data requirements of reverse-engineering algorithms Winfried Just vastly underdetermined. It is therefore important to estimate the probability that a given algorithm of different algorithms can be made. We also give an example of how expected algorithm performance can

  20. Automotive Turbocharging: Industrial Requirements and Technology...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Turbocharging: Industrial Requirements and Technology Developments Automotive Turbocharging: Industrial Requirements and Technology Developments Significant improvements in...

  1. In Lieu of Required Parking

    E-Print Network [OSTI]

    Shoup, Donald C.

    2001-01-01

    1997. Stadium Expansion Parking Plan and TransportationR. , and H . Levinson. 1990. Parking, Westport, Conn. : EnoWillson, R. 1995. Suburban parking requirements: A tacit

  2. Fusion Energy Sciences Network Requirements

    E-Print Network [OSTI]

    Dart, Eli

    2014-01-01

    Division, and the Office of Fusion Energy Sciences. This isFusion Energy Sciences NetworkRequirements Office of Fusion Energy Sciences Energy

  3. Blog Requirements and Best Practices

    Office of Energy Efficiency and Renewable Energy (EERE)

    Here you'll find the requirements and best practices for creating and maintaining an Office of Energy Efficiency and Renewable Energy (EERE) blog.

  4. Animation Requirements for the Web

    Office of Energy Efficiency and Renewable Energy (EERE)

    Animations include dynamic elements such as interactive images and games. For developing animations, follow the Office of Energy Efficiency and Renewable Energy's (EERE's) design and coding requirements.

  5. Making food labels social: The impact of colour of nutritional labels and injunctive norms on perceptions and choice of snack foods

    E-Print Network [OSTI]

    Vasiljevic, Milica; Pechey, Rachel; Marteau, Theresa M.

    2015-04-01

    in supermarket settings in the UK and Australia found that the introduction of front-of-pack traffic light labels did not lead to healthier food purchasing (Sacks, Rayner, & Swinburn, 2009; Sacks, Tikellis, Millar, & Swinburn, 2011). More recent research has... .11.009. Rozin, P., & Royzman, E. B. (2001). Negativity bias, negativity dominance, and contagion. Personality and Social Psychology Review, 5, 296320. doi:10.1207/ S15327957PSPR0504_2. Sacks, G., Rayner, M., & Swinburn, B. (2009). Impact of front...

  6. Alternative Fuels Data Center: Status Update: Requirements Have Not Changed

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlenderBusiness Case for E85 FuelDispenser(June 2008)

  7. Global Structure of a Three-Way Junction in a Phi29 Packaging RNA Dimer Determined Using Site-Directed Spin Labeling

    SciTech Connect (OSTI)

    Zhang, Xiaojun; Tung, Chang-Shung; Sowa, Glenna; Hatmal, Ma'mon M.; Haworth, Ian S.; Qin, Peter Z.

    2012-02-08

    The condensation of bacteriophage phi29 genomic DNA into its preformed procapsid requires the DNA packaging motor, which is the strongest known biological motor. The packaging motor is an intricate ring-shaped protein/RNA complex, and its function requires an RNA component called packaging RNA (pRNA). Current structural information on pRNA is limited, which hinders studies of motor function. Here, we used site-directed spin labeling to map the conformation of a pRNA three-way junction that bridges binding sites for the motor ATPase and the procapsid. The studies were carried out on a pRNA dimer, which is the simplest ring-shaped pRNA complex and serves as a functional intermediate during motor assembly. Using a nucleotide-independent labeling scheme, stable nitroxide radicals were attached to eight specific pRNA sites without perturbing RNA folding and dimer formation, and a total of 17 internitroxide distances spanning the three-way junction were measured using Double Electron-Electron Resonance spectroscopy. The measured distances, together with steric chemical constraints, were used to select 3662 viable three-way junction models from a pool of 65 billion. The results reveal a similar conformation among the viable models, with two of the helices (HT and HL) adopting an acute bend. This is in contrast to a recently reported pRNA tetramer crystal structure, in which HT and HL stack onto each other linearly. The studies establish a new method for mapping global structures of complex RNA molecules, and provide information on pRNA conformation that aids investigations of phi29 packaging motor and developments of pRNA-based nanomedicine and nanomaterial.

  8. Handbook of Academic Requirements & Procedures

    E-Print Network [OSTI]

    Kounaves, Samuel P.

    Handbook of Academic Requirements & Procedures for the Chemistry Graduate Program PLEASE NOTE: This version of the Handbook must be used by all students who started during the Spring 2012 semester or later is a central activity. 1.2 Purpose and Content of the Handbook. A detailed account of the academic requirements

  9. Handbook of Academic Requirements & Procedures

    E-Print Network [OSTI]

    Kounaves, Samuel P.

    Handbook of Academic Requirements & Procedures for the Chemistry Graduate Program PLEASE NOTE: This version of the Handbook can be used by students who started during or before the Fall 2011 semester activity. 1.2 Purpose and Content of the Handbook. A detailed account of the academic requirements

  10. 3. MATERIAL CERTIFICATIONS REQUIRED. 100% DYE PENETRANT INSPECTION REQUIRED.

    E-Print Network [OSTI]

    McDonald, Kirk

    WELDS SHOULD BE MINIMIZED. NO CODE STAMP REQUIRED. IN ACCORDANCE WITH ASME SECTION IX. 1. WELDING and applicable 1. ALL DIMENSIONS ARE IN INCHES 2. INTERPRET DIMENSIONS AND TOLERANCES PER ASME Y14.5M 3. MACHINED

  11. High-resolution x-ray diffraction microscopy of specifically labeled yeast cells

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Nelson, Johanna; Huang, Xiaojing; Steinbrener, Jan; Shapiro, David; Kirz, Janos; Marchesini, Stephano; Neiman, Aaron M.; Turner, Joshua J.; Jacobsen, Chris

    2010-04-20

    X-ray diffraction microscopy complements other x-ray microscopy methods by being free of lens-imposed radiation dose and resolution limits, and it allows for high-resolution imaging of biological specimens too thick to be viewed by electron microscopy. We report here the highest resolution (11-13 nm) x-ray diffraction micrograph of biological specimens, and a demonstration of molecular-specific gold labeling at different depths within cells via through-focus propagation of the reconstructed wavefield. The lectin concanavalin A conjugated to colloidal gold particles was used to label the ?-mannan sugar in the cell wall of the yeast Saccharomyces cerevisiae. Cells were plunge-frozen in liquid ethane andmorefreeze-dried, after which they were imaged whole using x-ray diffraction microscopy at 750 eV photon energy.less

  12. Label-free identification of individual bacteria using Fourier transform light scattering

    E-Print Network [OSTI]

    Jo, YoungJu; Kim, Min-hyeok; Park, HyunJoo; Kang, Suk-Jo; Park, YongKeun

    2015-01-01

    Rapid identification of bacterial species is crucial in medicine and food hygiene. In order to achieve rapid and label-free identification of bacterial species at the single bacterium level, we propose and experimentally demonstrate an optical method based on Fourier transform light scattering (FTLS) measurements and statistical classification. For individual rod-shaped bacteria belonging to four bacterial species (Listeria monocytogenes, Escherichia coli, Lactobacillus casei, and Bacillus subtilis), two-dimensional angle-resolved light scattering maps are precisely measured using FTLS technique. The scattering maps are then systematically analyzed, employing statistical classification in order to extract the unique fingerprint patterns for each species, so that a new unidentified bacterium can be identified by a single light scattering measurement. The single-bacterial and label-free nature of our method suggests wide applicability for rapid point-of-care bacterial diagnosis.

  13. High-resolution x-ray diffraction microscopy of specifically labeled yeast cells

    SciTech Connect (OSTI)

    Nelson, Johanna; Huang, Xiaojing; Steinbrener, Jan; Shapiro, David; Kirz, Janos; Marchesini, Stephano; Neiman, Aaron M.; Turner, Joshua J.; Jacobsen, Chris

    2010-04-20

    X-ray diffraction microscopy complements other x-ray microscopy methods by being free of lens-imposed radiation dose and resolution limits, and it allows for high-resolution imaging of biological specimens too thick to be viewed by electron microscopy. We report here the highest resolution (11-13 nm) x-ray diffraction micrograph of biological specimens, and a demonstration of molecular-specific gold labeling at different depths within cells via through-focus propagation of the reconstructed wavefield. The lectin concanavalin A conjugated to colloidal gold particles was used to label the ?-mannan sugar in the cell wall of the yeast Saccharomyces cerevisiae. Cells were plunge-frozen in liquid ethane and freeze-dried, after which they were imaged whole using x-ray diffraction microscopy at 750 eV photon energy.

  14. PV cohomology of pinwheel tilings, their integer group of coinvariants and gap-labelling

    E-Print Network [OSTI]

    Moustafa, Haja

    2009-01-01

    In this paper, we first remind how we can see the "hull" of the pinwheel tiling as an inverse limit of simplicial complexes (Anderson and Putnam) and we then adapt the PV cohomology introduced in a paper of Bellissard and Savinien to define it for pinwheel tilings. We then prove that this cohomology is isomorphic to the integer \\v{C}ech cohomology of the quotient of the hull by $S^1$ which let us prove that the top integer \\v{C}ech cohomology of the hull is in fact the integer group of coinvariants on some transversal of the hull. The gap-labelling for pinwheel tilings is then proved and we end this article by an explicit computation of this gap-labelling, showing that $\\mu^t \\big(C(\\Xi,\\ZZ) \\big) = \\dfrac{1}{264} \\ZZ [\\dfrac{1}{5}]$.

  15. Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMassR&D100 Winners *ReindustrializationEnergyWindNO. DE-SOL-0008418Annual

  16. Energy expenditure and socioeconomic status in Guatemala as measured by the doubly labelled water method

    SciTech Connect (OSTI)

    Stein, T.P.; Johnston, F.E.; Greiner, L.

    1988-02-01

    The energy expenditure of lower (group 1) and upper socioeconomic group females (group 2) from a marginal community in Guatemala City was determined by using the doubly labelled water method. Energy expenditure values were 1925 +/- 66 (mean, SEM) kcal/d (group 1) and 2253 +/- 145 kcal/d group 2 (p less than 0.03). About half of this difference can be attributed to size.

  17. Actes JFPC 2012 Compilation de CSP en Set-labeled Diagram

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    Actes JFPC 2012 Compilation de CSP en Set-labeled Diagram Alexandre Niveau Hel`ene Fargier C parfois ^etre executees en ligne et en temps limite. Dans ce cas, la resolution du CSP n'est pas asseze- sente l'assignation d'une variable ; l'ensemble des solu- tions d'un CSP correspond `a l'ensemble des

  18. Apparatus for reading two-dimensional electrophoretograms containing. beta. -ray-emitting labeled compounds

    DOE Patents [OSTI]

    Anderson, H.L.; Kinnison, W.W.; Lillberg, J.W.

    1985-04-30

    An apparatus and method for electronically reading planar two-dimensional ..beta..-ray emitter-labeled gel electrophoretograms. A single, flat rectangular multiwire proportional chamber is placed in close proximity to the gel and the assembly placed in an intense uniform magnetic field disposed in a perpendicular manner to the rectangular face of the proportional chamber. Beta rays emitted in the direction of the proportional chamber are caused to execute helical motions which substantially preserve knowledge the coordinates of their origin in the gel. Perpendicularly oriented, parallel wire, parallel plane cathodes electronically sense the location of the ..beta..-rays from ionization generated thereby in a detection gas coupled with an electron avalanche effect resulting from the action of a parallel wire anode located therebetween. A scintillator permits the present apparatus to be rendered insensitive when signals are generated from cosmic rays incident on the proportional chamber. Resolution for concentrations of radioactive compounds in the gel exceeds 700-..mu..m. The apparatus and method of the present invention represent a significant improvement over conventional autoradiographic techniques in dynamic range, linearity and sensitivity of data collection. A concentration and position map for gel electrophoretograms having significant concentrations of labeled compounds and/or highly radioactive labeling nuclides can generally be obtained in less than one hour.

  19. Apparatus and method for reading two-dimensional electrophoretograms containing .beta.-ray-emitting labeled compounds

    DOE Patents [OSTI]

    Anderson, Herbert L. (Santa Fe, NM); Kinnison, W. Wayne (Los Alamos, NM); Lillberg, John W. (Los Alamos, NM)

    1987-01-01

    Apparatus and method for electronically reading planar two dimensional .beta.-ray emitter-labeled gel electrophoretograms. A single, flat rectangular multiwire proportional chamber is placed in close proximity to the gel and the assembly placed in an intense uniform magnetic field disposed in a perpendicular manner to the rectangular face of the proportional chamber. Beta rays emitted in the direction of the proportional chamber are caused to execute helical motions which substantially preserve knowledge of the coordinates of their origin in the gel. Perpendicularly oriented, parallel wire, parallel plane cathodes electronically sense the location of the .beta.-rays from ionization generated thereby in a detection gas coupled with an electron avalanche effect resulting from the action of a parallel wire anode located therebetween. A scintillator permits the present apparatus to be rendered insensitive when signals are generated from cosmic rays incident on the proportional chamber. Resolution for concentrations of radioactive compounds in the gel exceeds 700 .mu.m. The apparatus and method of the present invention represent a significant improvement over conventional autoradiographic techniques in dynamic range, linearity and sensitivity of data collection. A concentration and position map for gel electrophoretograms having significant concentrations of labeled compounds and/or highly radioactive labeling nuclides can generally be obtained in less than one hour.

  20. Calendar Year 2007 Program Benefits for U.S. EPA Energy Star Labeled Products: Expanded Methodology

    SciTech Connect (OSTI)

    Sanchez, Marla; Homan, Gregory; Lai, Judy; Brown, Richard

    2009-09-24

    This report provides a top-level summary of national savings achieved by the Energy Star voluntary product labeling program. To best quantify and analyze savings for all products, we developed a bottom-up product-based model. Each Energy Star product type is characterized by product-specific inputs that result in a product savings estimate. Our results show that through 2007, U.S. EPA Energy Star labeled products saved 5.5 Quads of primary energy and avoided 100 MtC of emissions. Although Energy Star-labeled products encompass over forty product types, only five of those product types accounted for 65percent of all Energy Star carbon reductions achieved to date, including (listed in order of savings magnitude)monitors, printers, residential light fixtures, televisions, and furnaces. The forecast shows that U.S. EPA?s program is expected to save 12.2 Quads of primary energy and avoid 215 MtC of emissions over the period of 2008?2015.

  1. Labeling of Cp-105,191. Unusual findings on triphenyltin hydride reduction of an aryl iodide

    SciTech Connect (OSTI)

    McCarthy, P.A.; Diaz, C.L.; Zawistoski, M.P.

    1995-12-01

    CP-105,191 (1) is a potent, selective and systemically-available inhibitor of acyl-coenzyme A:cholesterol acyl transferase. We needed to make tritium-labeled 1 in order to facilitate the preclinical evaluation of the pharmacokinetics and systemic anti-atherosclerosis effects of 1. Desiring to introduce the tritium as the last step in the synthesis, we opted for introduction of the tritium into the quinoline nucleus via reduction of an 8-iodo species (8, synthesis to be described). To our surprise, treatment of 8 with distilled triphenyltin deuteride and catalytic AIBN in diglyme at reflux for 2 hours gave 67-72% yield of 1 with no deuterium incorporation. Consideration of these results and others to be presented suggests that the solvent is participating in radical chain propagation and that this reaction was unsuitable for tritium labeling. After these results, we found that reduction of 8 with atmospheric pressure of deuterium catalyzed by palladium on carbon in ethanol and triethylamine gave 75-95% yield of 1 with complete deuterium incorporation at C8 of the quinoline ring. The same reaction using 4 Ci of tritium gas gave 1.8 Ci of tritium-labeled 1 with specific activity of 20 Ci/mmole and 97% radiochemical purity.

  2. The Effects of Mandatory Country-of-Origin Labeling on Canadian/U.S. Live Hog and Feeder Pig Trade

    E-Print Network [OSTI]

    Thevenaz, Shad Arthur Michel

    2012-02-14

    The final implementation of Mandatory Country-of-Origin Labeling has caused some U.S. packing plants and finishing operations to discontinue using Canadian live hogs and feeder pigs in their operations thereby reducing trade. Using a system...

  3. A unique radioisotopic label as a new concept for safeguarding and tagging of long-term stored items and waste

    E-Print Network [OSTI]

    Chernikova, Dina

    2013-01-01

    The present paper discuss a novel method of tagging and labeling of waste casks, copper canisters, spent fuel containers, mercury containers, waste pack- ages and other items. In particular, it is related to the development of new long-term security identification tags/labels that can be applied to articles for carrying information about the content, inventory tracking, prevention of falsifi- cation and theft etc. It is suggested to use a unique combination of radioisotopes with different predictable length of life, as a label of the items. The possibil- ity to realize a multidimensional bar code symbology is proposed as an option for a new labeling method. The results of the first tests and evaluations of this are shown and discussed in the paper. The invention is suitable for use in items assigned to long-term (hundreds of years) storing or for final repositories. Alternative field of use includes fresh nuclear fuel handling and shipment of goods.

  4. A unique radioisotopic label as a new concept for safeguarding and tagging of long-term stored items and waste

    E-Print Network [OSTI]

    Dina Chernikova; Kare Axell

    2015-01-15

    The present paper discuss a novel method of tagging and labeling of waste casks, copper canisters, spent fuel containers, mercury containers, waste pack- ages and other items. In particular, it is related to the development of new long-term security identification tags/labels that can be applied to articles for carrying information about the content, inventory tracking, prevention of falsifi- cation and theft etc. It is suggested to use a unique combination of radioisotopes with different predictable length of life, as a label of the items. The possibil- ity to realize a multidimensional bar code symbology is proposed as an option for a new labeling method. The results of the first tests and evaluations of this are shown and discussed in the paper. The invention is suitable for use in items assigned to long-term (hundreds of years) storing or for final repositories. Alternative field of use includes fresh nuclear fuel handling and shipment of goods.

  5. Mass-related inversion symmetry breaking and phonon self-energy renormalization in isotopically labeled AB-stacked bilayer graphene

    E-Print Network [OSTI]

    Araujo, Paulo Antonio Trinidade

    A mass-related symmetry breaking in isotopically labeled bilayer graphene (2LG) was investigated during in-situ electrochemical charging of AB stacked (AB-2LG) and turbostratic (t-2LG) layers. The overlap of the two ...

  6. The 1993 nutrition label: development of a rating system and a perspective by nutrition and food industry professionals

    E-Print Network [OSTI]

    Osborn, Lacye Ann

    1994-01-01

    The objectives of this study were to develop a nutrition scoring system which would combine the nutritional information on the new label into a single number, to identify strengths and weaknesses of the new nutritional ...

  7. Progress towards Managing Residential Electricity Demand: Impacts of Standards and Labeling for Refrigerators and Air Conditioners in India

    E-Print Network [OSTI]

    McNeil, Michael A.

    2010-01-01

    Study of Coal in India's Future Energy Scope. Tata EnergyLabeling and Energy Efficiency Standards in India. Indianproducts: The case of India." Energy Policy 36(9): CLASP .

  8. Metal dependent structure, dynamics, and function in RNA measured by site-directed spin labeling and EPR spectroscopy

    E-Print Network [OSTI]

    Kim, Nak-Kyoon

    2007-04-25

    -directed spin labeling (SDSL) and EPR spectroscopy, distances in RNA duplexes, TAR RNA, and the hammerhead ribozyme have been measured to investigate RNA structures. Kinetic measurements have been performed in the extended hammerhead ribozyme to correlate...

  9. Meeting Federal Energy Security Requirements

    Office of Energy Efficiency and Renewable Energy (EERE)

    Presentationgiven at at the Fall 2012 Federal Utility Partnership Working Group (FUPWG) meetingdiscusses the opportunity to increase the scope of federal-utility partnerships for meeting energy security requirements.

  10. POSTGRADUATE PROGRAMMES Procedures and Requirements

    E-Print Network [OSTI]

    Jagannatham, Aditya K.

    Engineering, Materials Science, Mechanical Engineering, Nuclear Engineering and Technology and Photonics Statistics), Mechanical Engineering, Nuclear Engineering and Technology, Photonics Science and Engineering(1) POSTGRADUATE PROGRAMMES Procedures and Requirements INDIAN INSTITUTE OF TECHNOLOGY KANPUR

  11. Psychology Department Mandatory Advising Requirement

    E-Print Network [OSTI]

    10/2011 Psychology Department Mandatory Advising Requirement Instructions 1) Student completes Part advisor's signature. 4) Once the form is signed, submit form to Psychology Department, EP 301 to clear

  12. Fusion technology status and requirements

    SciTech Connect (OSTI)

    Thomassen, K.I.

    1982-01-26

    This paper summarizes the status of fusion technology and discusses the requirements to be met in order to build a demonstration fusion plant. Strategies and programmatic considerations in pursuing engineering feasibility are also outlined.

  13. SOFTWARE QUALITY & SYSTEMS ENGINEERING PROGRAM: Requirements...

    Broader source: Energy.gov (indexed) [DOE]

    requirements management activities SOFTWARE QUALITY & SYSTEMS ENGINEERING PROGRAM: Requirements Management Checklist More Documents & Publications SOFTWARE QUALITY & SYSTEMS...

  14. Project X functional requirements specification

    SciTech Connect (OSTI)

    Holmes, S.D.; Henderson, S.D.; Kephart, R.; Kerby, J.; Kourbanis, I.; Lebedev, V.; Mishra, S.; Nagaitsev, S.; Solyak, N.; Tschirhart, R.; /Fermilab

    2012-05-01

    Project X is a multi-megawatt proton facility being developed to support a world-leading program in Intensity Frontier physics at Fermilab. The facility is designed to support programs in elementary particle and nuclear physics, with possible applications to nuclear energy research. A Functional Requirements Specification has been developed in order to establish performance criteria for the Project X complex in support of these multiple missions, and to assure that the facility is designed with sufficient upgrade capability to provide U.S. leadership for many decades to come. This paper will briefly review the previously described Functional Requirements, and then discuss their recent evolution.

  15. Project X functional requirements specification

    E-Print Network [OSTI]

    Holmes, S D; Kephart, R; Kerby, J; Kourbanis, I; Lebedev, V; Mishra, S; Nagaitsev, S; Solyak, N; Tschirhart, R

    2012-01-01

    Project X is a multi-megawatt proton facility being developed to support a world-leading program in Intensity Frontier physics at Fermilab. The facility is designed to support programs in elementary particle and nuclear physics, with possible applications to nuclear energy research. A Functional Requirements Specification has been developed in order to establish performance criteria for the Project X complex in support of these multiple missions, and to assure that the facility is designed with sufficient upgrade capability to provide U.S. leadership for many decades to come. This paper will briefly review the previously described Functional Requirements, and then discuss their recent evolution.

  16. F-18 Labeled Diabody-Luciferase Fusion Proteins for Optical-ImmunoPET

    SciTech Connect (OSTI)

    Wu, Anna M

    2013-01-18

    The goal of the proposed work is to develop novel dual-labeled molecular imaging probes for multimodality imaging. Based on small, engineered antibodies called â??diabodiesâ?, these probes will be radioactively tagged with Fluorine-18 for PET imaging, and fused to luciferases for optical (bioluminescence) detection. Performance will be evaluated and validated using a prototype integrated optical-PET imaging system, OPET. Multimodality probes for optical-PET imaging will be based on diabodies that are dually labeled with 18F for PET detection and fused to luciferases for optical imaging. 1) Two sets of fusion proteins will be built, targeting the cell surface markers CEA or HER2. Coelenterazine-based luciferases and variant forms will be evaluated in combination with native substrate and analogs, in order to obtain two distinct probes recognizing different targets with different spectral signatures. 2) Diabody-luciferase fusion proteins will be labeled with 18F using amine reactive [18F]-SFB produced using a novel microwave-assisted, one-pot method. 3) Sitespecific, chemoselective radiolabeling methods will be devised, to reduce the chance that radiolabeling will inactivate either the target-binding properties or the bioluminescence properties of the diabody-luciferase fusion proteins. 4) Combined optical and PET imaging of these dual modality probes will be evaluated and validated in vitro and in vivo using a prototype integrated optical-PET imaging system, OPET. Each imaging modality has its strengths and weaknesses. Development and use of dual modality probes allows optical imaging to benefit from the localization and quantitation offered by the PET mode, and enhances the PET imaging by enabling simultaneous detection of more than one probe.

  17. Electrochemical detection of leukemia oncogenes using enzyme-loaded carbon nanotube labels

    SciTech Connect (OSTI)

    Lee, Ai Cheng; Du, Dan; Chen, Baowei; Heng, Chew-Kiat; Lim, Tit-Meng; Lin, Yuehe

    2014-09-07

    Here we describe an ultrasensitive electrochemical nucleic acids assay amplified by carbon nanotubes (CNTs)-based labels for the detection of human acute lymphocytic leukemia (ALL) related p185 BCR-ABL fusion transcript. The carboxylated CNTs were functionalized with horseradish peroxidase (HRP) molecules and target-specific detection probes (DP) via diimide-activated amidation, and used to label and amplify target hybridization signal. The activity of captured HRP was monitored by square-wave voltammetry measuring the electroactive enzymatic product in the presence of 2-aminophenol and hydrogen peroxide substrate solution. The effect of DP and HRP loading of the CNT-based labels on its signal-to-noise ratio of electrochemical detection was studied systematically for the first time. Under optimized conditions, the signal-amplified assay achieved a detection limit of 83 fM targets oligonuecleotides and a 4-order wide dynamic range of target concentration. The resulting assay allowed a robust discrimination between the perfect match and a three-base mismatch sequence. When subjected to full-length (491 bp) DNA oncogene, the approach demonstrated a detection limit of approximately 33 pg of the target gene. The high sensitivity and specificity of assay enabled PCR-free detection of target transcripts in as little as 65 ng of mRNA extracted from positive ALL cell lines SUP-B15, in comparison to those obtained from negative cell lines HL-60. The approach holds promise for simple, low cost and ultrasensitive electrochemical nucleic acids detection in portable devices, point-of-care and early disease diagnostic applications.

  18. PASSWORD REQUIRED COMPUTER(S)

    E-Print Network [OSTI]

    Clayton, Dale H.

    Release Accessible Printer EQUIPMENT CHECKOUT CLASSROOM SUPPORT POSTER & 3D PRINTING BOOK, FICHE, & FILM STATIONS SCANNING STATIONS 3D SCANNER BLOOMBERG TERMINAL Information,Research, & Technology AssisstanceN LEGEND COMPUTERS PASSWORD REQUIRED COMPUTER(S) QUICK SEARCH PRINTER(S) SERVICE DESK FIRE

  19. Computer Science Graduation Requirements Checklist

    E-Print Network [OSTI]

    Zadok, Erez

    Computer Science Graduation Requirements Checklist Fall 2008 Computer Science Courses Course Gr. Sem. Comments CSE 114 Computer Science I [prerequisite: CSE 110] CSE 214 Computer Science II CSE 215 Foundations of Computer Science CSE 219 Computer Science III CSE 220 Computer Organization CSE 300 Writing

  20. Computer Science Graduation Requirements Checklist

    E-Print Network [OSTI]

    Zadok, Erez

    Computer Science Graduation Requirements Checklist Fall 2009 Computer Science Courses Course Gr. Sem. Comments CSE 114 Computer Science I [prerequisite: CSE 110] CSE 214 Computer Science II CSE 215 Foundations of Computer Science CSE 219 Computer Science III CSE 220 Computer Organization CSE 300 Writing

  1. APPLICATION REQUIREMENTS: Admission Applica on

    E-Print Network [OSTI]

    Rainforth, Emma C.

    basis. An interview may be required. MS Educa onal Technology Program: A state issued teaching cer: State issued teaching cer ficate. Three years of professional experience as a teacher:_____________ __________ ________________ Sex: Male Female Street Address Town or City County State Zip Code Home Telephone

  2. FREH CONFERENCE ROOMS Scheduling Requirements

    E-Print Network [OSTI]

    Pittendrigh, Barry

    1/12/2015 FREH CONFERENCE ROOMS Scheduling Requirements: The 1st or 2nd Floor Operations Clerk it in the location or the body of the room reservation. Schedule ALL conference rooms and/or equipment needs ONLY" dumpster outside by the loading dock. Please CANCEL the conference room reservation

  3. Handbook of Academic Requirements & Procedures

    E-Print Network [OSTI]

    Kounaves, Samuel P.

    Handbook of Academic Requirements & Procedures for the Chemistry/Biotechnology Graduate Program in which chemical/biotechnology research is a central activity. 1.2 Purpose and Content of the Handbook in this handbook should be addressed to the Chair of the joint Chemistry/Biotechnology Joint Graduate Commit

  4. Audio Requirements for the Web

    Broader source: Energy.gov [DOE]

    Audio-only fileswhether they are downloaded from a page or distributed via a podcastmust be accessible to all visitors of the Office of Energy Efficiency and Renewable Energy (EERE) website. For developing and posting audio-only files, follow these requirements and best practices.

  5. Action Required An extra layer

    E-Print Network [OSTI]

    Fernandez, Eduardo

    Action Required An extra layer of protection m A Securian Company State of Florida Group Term Life by Minnesota Life Insurance Company, at rates negotiated exclusively for employees of the State of Florida's right for you and your family, it's important to think about the amount of money your family would need

  6. Metabolomics relative quantitation with mass spectrometry using chemical derivatization and isotope labeling

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    O'Maille, Grace; Go, Eden P.; Hoang, Linh; Want, Elizabeth J.; Smith, Colin; O'Maille, Paul; Nordstrm, Anders; Morita, Hirotoshi; Qin, Chuan; Uritboonthai, Wilasinee; et al

    2008-01-01

    Comprehensive detection and quantitation of metabolites from a biological source constitute the major challenges of current metabolomics research. Two chemical derivatization methodologies, butylation and amination, were applied to human serum for ionization enhancement of a broad spectrum of metabolite classes, including steroids and amino acids. LC-ESI-MS analysis of the derivatized serum samples provided a significant signal elevation across the total ion chromatogram to over a 100-fold increase in ionization efficiency. It was also demonstrated that derivatization combined with isotopically labeled reagents facilitated the relative quantitation of derivatized metabolites from individual as well as pooled samples.

  7. New Solutions Require New Thinking

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematicsEnergyInterested Parties -DepartmentAvailable for Public CommentofCapabilitiesSolutions Require

  8. Made with Renewable Energy: How and Why Companies are Labeling Consumer Products

    SciTech Connect (OSTI)

    Baker Brannan, D.; Heeter, J.; Bird, L.

    2012-03-01

    Green marketing--a marketing strategy highlighting the environmental attributes of a product, often through the use of labels or logos--dates back to the 1970s. It did not proliferate until the 1990s, however, when extensive market research identified a rapidly growing group of consumers with a heightened concern for the environment. This group expressed not only a preference for green products but also a willingness to pay a premium for such products. The response was a surge in green marketing that lasted through the early 1990s. This report discusses the experience of companies that communicate to consumers that their products are 'made with renewable energy.' For this report, representatives from 20 companies were interviewed and asked to discuss their experiences marketing products produced using renewable energy. The first half of this report provides an overview of the type of companies that have labeled products or advertised them as being made with renewable energy. It also highlights the avenues companies use to describe their use of renewable energy. The second half of the report focuses on the motivations for making on-product claims about the use of renewable energy and the challenges in doing so.

  9. Peptide affinity labels for thrombin and other trypsin-like proteases

    DOE Patents [OSTI]

    Shaw, E.N.; Kettner, C.A.

    1982-03-09

    A peptide affinity label is disclosed of the formula (I): as given in the patent wherein X is a radical capable of acting as a leaving group in a nucleophilic substitution reaction; A is an aromatic amino acid residue; B is H, or a C[sub 1]--C[sub 4] alkyl group, or aryl; Y is selected from the group consisting of hydrogen, aroyl, C[sub 1]--C[sub 6] acyl, and Q--(A)--[sub n], wherein Q = hydrogen, aroyl, or C[sub 1]--C[sub 6] acyl, n = 1--10, A is an amino acid residue selected from the aliphatic, hydroxy-containing, carboxylic acid group, and amide-thereofcontaining, aromatic, sulfur-containing and imino-containing amino acids; and wherein J is selected from the group consisting of --CH[sub 2]--, --CH[sub 2]--CH[sub 2]--, --CH[sub 2]--CH[sub 2]--CH[sub 2]--, --CH[double bond]CH-- and --CH(OH)--CH[sub 2]. The affinity label is useful for irreversibly inactivating thrombin and trypsin-like enzymes and may be used as a potential anticlotting agent. 2 figs.

  10. Velocity requirements for causality violation

    E-Print Network [OSTI]

    Giovanni Modanese

    2015-01-18

    We re-examine the "Regge-Tolman paradox" with reference to some recent experimental results. It is straightforward to find a formula for the velocity v of the moving system required to produce causality violation. This formula typically yields a velocity very close to the speed of light (for instance, v/c > 0.97 for X-shaped microwaves), which raises some doubts about the real physical observability of the violations. We then compute the velocity requirement introducing a delay between the reception of the primary signal and the emission of the secondary. It turns out that in principle for any delay it is possible to find moving observers able to produce active causal violation. This is mathematically due to the singularity of the Lorentz transformations for beta to 1. For a realistic delay due to the propagation of a luminal precursor, we find that causality violations in the reported experiments are still more unlikely (v/c > 0.989), and even in the hypothesis that the superluminal propagation velocity goes to infinity, the velocity requirement is bounded by v/c > 0.62. We also prove that if two macroscopic bodies exchange energy and momentum through superluminal signals, then the swap of signal source and target is incompatible with the Lorentz transformations; therefore it is not possible to distinguish between source and target, even with reference to a definite reference frame.

  11. BIOMECHANICAL ENGINEERING SubPlan Requirements

    E-Print Network [OSTI]

    Cafarella, Michael J.

    BIOMECHANICAL ENGINEERING SubPlan Requirements Campus: UMICH RG = Requirement Group Career:UENG RQ = Requirement Program: LN = Line Plan: 0880BSE Sub-Plan: BIOMECH RG 6860 BIOMECHANICAL CONCENTRATION

  12. Radiation Protection Guidance Hospital Staff

    E-Print Network [OSTI]

    Kay, Mark A.

    ............................................................................................... 13 Labeling requirements .............................................................................................. 13 Radioactive Package Receipt Requirements

  13. Cooperating Agencies in Implementing the Procedural Requirements...

    Energy Savers [EERE]

    Agencies in Implementing the Procedural Requirements of the National Environmental Policy Act Cooperating Agencies in Implementing the Procedural Requirements of the National...

  14. DOE-STD-1104 Requirements Crosswalk

    Office of Environmental Management (EM)

    properly indicates the required functional classification (i.e., safety class versus safety significant) and seismic and other NPH design requirements (i.e., the proper seismic...

  15. Cold vacuum drying facility design requirements

    SciTech Connect (OSTI)

    IRWIN, J.J.

    1999-07-01

    This document provides the detailed design requirements for the Spent Nuclear Fuel Project Cold Vacuum Drying Facility. Process, safety, and quality assurance requirements and interfaces are specified.

  16. Studying the Communications Requirements of Electric Utilities...

    Energy Savers [EERE]

    Studying the Communications Requirements of Electric Utilities to Inform Federal Smart Grid Policies- Public Meeting Studying the Communications Requirements of Electric Utilities...

  17. Bioinformatics and Genomics Degree Requirements Booklet

    E-Print Network [OSTI]

    dePamphilis, Claude

    Bioinformatics and Genomics Degree Requirements Booklet Fall 2010 #12;Contents Course Requirements Bioinformatics and Genomics Curriculum -------------------------------------------------------8 General #12;Bioinformatics and Genomics Option (BG

  18. DE-SOL-0008449 REPORTING REQUIREMENTS CHECKLIST

    National Nuclear Security Administration (NNSA)

    Independence Avenue SW Washington DC 20585 E. Task order project support Appendix A: Web-Based Reporting System Requirements Web-Based Reporting System Requirements 1....

  19. Energy-Efficiency Labels and Standards: A Guidebook forAppliances, Equipment, and Lighting - 2nd Edition

    SciTech Connect (OSTI)

    Wiel, Stephen; McMahon, James E.

    2005-04-28

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and several other organizations identified on the cover of this guidebook recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labeling programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This second edition of the guidebook was prepared over the course of the past year, four years after the preparation of the first edition, with a significant contribution from the authors and reviewers mentioned previously. Their diligent participation helps maintain this book as the international guidance tool it has become. The lead authors would like to thank the members of the Communications Office of the Environmental Energy Technologies Division, Lawrence Berkeley National Laboratory for their support in the development, production, and distribution of the guidebook. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development, implementation, maintenance, and evaluation of the programs and on the design of the labels and standards themselves. In addition, it directs the reader to references and other resources likely to be useful in conducting the activities described and includes a chapter on energy policies and programs that complement appliance efficiency labels and standards. This guidebook attempts to reflect the essential framework of labeling and standards programs. It is the intent of the authors and sponsor to distribute copies of this book worldwide, at no charge, for the general public benefit. The guidebook is also available on the web at www.clasponline.org and may be downloaded to be used intact or piecemeal for whatever beneficial purposes readers may conceive.

  20. Method to detect the end-point for PCR DNA amplification using an ionically labeled probe and measuring impedance change

    DOE Patents [OSTI]

    Miles, Robin R. (Danville, CA); Belgrader, Phillip (Severna Park, MD); Fuller, Christopher D. (Oakland, CA)

    2007-01-02

    Impedance measurements are used to detect the end-point for PCR DNA amplification. A pair of spaced electrodes are located on a surface of a microfluidic channel and an AC or DC voltage is applied across the electrodes to produce an electric field. An ionically labeled probe will attach to a complementary DNA segment, and a polymerase enzyme will release the ionic label. This causes the conductivity of the solution in the area of the electrode to change. This change in conductivity is measured as a change in the impedance been the two electrodes.

  1. Clean Air Act Requirements: Uranium Mill Tailings

    E-Print Network [OSTI]

    EPA'S Clean Air Act Requirements: Uranium Mill Tailings Radon Emissions Rulemaking Reid J. Rosnick Requirements for Uranium Operations (Clean Air Act) Subpart W Requirements (continued) Radon emission standard of 20 pCi/m2/sec -- annual reporting requirements, notification in advance of testing The radon

  2. Grantee Checklist for the Inspection & Monitoring Requirement

    Broader source: Energy.gov [DOE]

    This document walks Grantees through the Inspection and Monitoring requirement of the Quality Work Plan.

  3. Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents

    DOE Patents [OSTI]

    Jones, Alun G. (Newton Centre, MA); Davison, Alan (Needham, MA); Abrams, Michael J. (Westchester, PA)

    1987-01-01

    A method for preparing a coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta is disclosed. The method comprises preparing a soluble metal adduct of said isonitrile ligand by admixing said ligand with a salt of a displaceable metal having a complete d-electron shell selected from the group consisting of Zn, Ga, Cd, In, Sn, Hg, Tl, Pb and Bi to form a soluble metal-isonitrile salt, and admixing said metal isonitrile salt with a salt comprising said radioactive metal in a suitable solvent to displace said displaceable metal with the radioactive metal thereby forming said coordination. The complex is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.

  4. Rational Conversion of Affinity Reagents into Label-Free Sensors for Peptide Motifs by Designed Allostery

    SciTech Connect (OSTI)

    Huang, Jin; Koide, Shohei

    2010-05-25

    Optical biosensors for short peptide motifs, an important class of biomarkers, have been developed based on 'affinity clamps', a new class of recombinant affinity reagents. Affinity clamps are engineered by linking a peptide-binding domain and an antibody mimic domain based on the fibronectin type III scaffold, followed by optimization of the interface between the two. This two-domain architecture allows for the design of allosteric coupling of peptide binding to fluorescence energy transfer between two fluorescent proteins attached to the affinity clamp. Coupled with high affinity and specificity of the underlying affinity clamps and rationally designed mutants with different sensitivity, peptide concentrations in crude cell lysate were determined with a low nanomolar detection limit and over 3 orders of magnitude. Because diverse affinity clamps can be engineered, our strategy provides a general platform to generate a repertoire of genetically encoded, label-free sensors for peptide motifs.

  5. Tin-117m-labeled stannic (Sn.sup.4+) chelates

    DOE Patents [OSTI]

    Srivastava, Suresh C. (Setauket, NY); Meinken, George E. (Middle Island, NY); Richards, Powell (Bayport, NY)

    1985-01-01

    The radiopharmaceutical reagents of this invention and the class of Tin-117m radiopharmaceuticals are therapeutic and diagnostic agents that incorporate gamma-emitting nuclides that localize in bone after intravenous injection in mammals (mice, rats, dogs, and rabbits). Images reflecting bone structure or function can then be obtained by a scintillation camera that detects the distribution of ionizing radiation emitted by the radioactive agent. Tin-117m-labeled chelates of stannic tin localize almost exclusively in cortical bone. Upon intravenous injection of the reagent, the preferred chelates are phosphonate compounds, preferable, PYP, MDP, EHDP, and DTPA. This class of reagents is therapeutically and diagnostically useful in skeletal scintigraphy and for the radiotherapy of bone tumors and other disorders.

  6. Localized In Vivo 1H NMR Detection of Neurotransmitter Labeling in Rat Brain During Infusion of [1-13C] D-Glucose

    E-Print Network [OSTI]

    Localized In Vivo 1H NMR Detection of Neurotransmitter Labeling in Rat Brain During Infusion of [1 infusions of 13C-labeled glucose. Magn Reson Med 41:10771083, 1999. 1999 Wiley-Liss, Inc. Key words] glucose infusion In vivo 13C NMR spectroscopy with localization is emerg- ing as an important tool

  7. Improved Label and Liver Warning for Nonprescription Acetaminophen Products ! Acetaminophen is safe for self-care when used as directed, but has a

    E-Print Network [OSTI]

    Martin, Gail

    excluded for failure to meet inclusion criteria and early drop out. ! Baseline demographics: Well that their product labels will be used to help improve medication safety. PURPOSE ! Compare consumer preferences for, LIMITATIONS, CONCLUSIONS ! Study design: Prospective label comprehension study using design and implementation

  8. Assessment of the Impacts of Standards and Labeling Programs inMexico (four products).

    SciTech Connect (OSTI)

    Sanchez, Itha; Pulido, Henry; McNeil, Michael A.; Turiel, Isaac; della Cava, Mirka

    2007-06-12

    This study analyzes impacts from energy efficiency standards and labeling in Mexico from 1994 through 2005 for four major products: household refrigerators, room air conditioners, three-phase (squirrel cage) induction motors, and clothes washers. It is a retrospective analysis, seeking to assess verified impacts on product efficiency in the Mexican market in the first ten years after standards were implemented. Such an analysis allows the Mexican government to compare actual to originally forecast program benefits. In addition, it provides an extremely valuable benchmark for other countries considering standards, and to the energy policy community as a whole. The methodology for evaluation begins with historical test data taken for a large number of models of each product type between 1994 and 2005. The pre-standard efficiency of models in 1994 is taken as a baseline throughout the analysis. Model efficiency data were provided by an independent certification laboratory (ANCE), which tested products as part of the certification and enforcement mechanism defined by the standards program. Using this data, together with economic and market data provided by both government and private sector sources, the analysis considers several types of national level program impacts. These include: Energy savings; Environmental (emissions) impacts, and Net financial impacts to consumers, manufacturers and utilities. Energy savings impacts are calculated using the same methodology as the original projections, allowing a comparison. Other impacts are calculated using a robust and sophisticated methodology developed by the Instituto de Investigaciones Electricas (IIE) and Lawrence Berkeley National Laboratory (LBNL), in a collaboration supported by the Collaborative Labeling and Standards Program (CLASP).

  9. Nutrient Requirements of the Cow and Calf.

    E-Print Network [OSTI]

    Maddox, L. A. Jr.

    1965-01-01

    of the Cow and Calf TEXAS A&M UNIVERSITY TEXAS AGRICULTURAL EXTENSION SERVICE, J. E. Hutchison, Director College Station, Texas I contents I-. Energy Requirements, 3 Protein Requirements, 8 Daily Nutrient Requirements and Minimum Feed Quality, 9... and energy value of feeds antl nutrient requirements of If'. Information necessary to establish require- animals (Glossary of Energy Terms, 1962) . A :nts for several functions are limited and some- megacalorie is the same as a tllerm and is the pre- nes...

  10. Laboratory inspection follow up required Laboratory inspection completed

    E-Print Network [OSTI]

    Walker, Lawrence R.

    No evidence of food or drink consumption or storage inside lab Warning signs posted outside of door-centrifuge rotors (> 80,000 rpm) Vacuum systems are appropriately trapped Biological Biosafety signs and labels

  11. Genome informatics: Requirements and challenges

    SciTech Connect (OSTI)

    Robbins, R.J.

    1993-12-31

    Informatics of some kind will play a role in every aspect of the Human Genome Project (HGP); data acquisition, data analysis, data exchange, data publication, and data visualization. What are the real requirements and challenges? The primary requirement is clear thinking and the main challenge is design. If good design is lacking, the price will be failure of genome informatics and ultimately failure of the genome project itself. Scientists need good designs to deliver the tools necessary for acquiring and analyzing DNA sequences. As these tools become more efficient, they will need new tools for comparative genomic analyses. To make the tools work, the scientists will need to address and solve nomenclature issues that are essential, if also tedious. They must devise systems that will scale gracefully with the increasing flow of data. The scientists must be able to move data easily from one system to another, with no loss of content. As scientists, they will have failed in their responsibility to share results, should repeating experiments ever become preferable to searching the literature. Their databases must become a new kind of scientific literature and the scientists must develop ways to make electronic data publishing as routine as traditional journal publishing. Ultimately, they must build systems so advanced that they are virtually invisible. In summary, the HGP can be considered the most ambitious, most audacious information-management project ever undertaken. In the HGP, computers will not merely serve as tools for cataloging existing knowledge. Rather, they will serve as instruments, helping to create new knowledge by changing the way the scientists see the biological world. Computers will allow them to see genomes, just as radio telescopes let them see quasars and electron microscopes let them see viruses.

  12. Used Oil and Filter Disposal Used Oil: Create a segregated storage area or container. Label the container "Waste Oil Only".

    E-Print Network [OSTI]

    Maroncelli, Mark

    the container "Waste Oil Only". Maintain a written log to document all amounts and types of oil addedUsed Oil and Filter Disposal Used Oil: Create a segregated storage area or container. Label to the container. No solvents, oil contaminated with solvents, PCBs, non-petroleum based oils, or any other

  13. Fluorescence energy transfer efficiency in labeled yeast cytochrome c: a rapid screen for ion biocompatibility in aqueous ionic liquids

    SciTech Connect (OSTI)

    Baker, Sheila N; Zhao, Hua; Pandey, Siddharth; Heller, William T; Bright, Frank; Baker, Gary A

    2011-01-01

    A fluorescence energy transfer de-quenching assay was implemented to follow the equilibrium unfolding behaviour of site-specific tetramethylrhodamine-labelled yeast cytochrome c in aqueous ionic liquid solutions; additionally, this approach offers the prospect of naked eye screening for biocompatible ion combinations in hydrated ionic liquids.

  14. All-Optical Contention Resolution with TTL-Aware Selective 3R Regeneration in Optical-Label Switching

    E-Print Network [OSTI]

    Yoo, S. J. Ben

    as well as optical-burst switching and optical-circuit switching with flexible interoperability involving a prototype OLS router system that includes 3R regeneration [4]. At Node 1, the first subcarrier. The optical-label switching packets are split into two in energy to reach Node 3 as input channel 1

  15. A whole-forest 14C pulse-label study of microbial dynamics and root turnover (EBIS*)

    E-Print Network [OSTI]

    Post, Wilfred M.

    A whole-forest 14C pulse-label study of microbial dynamics and root turnover (EBIS*) Margaret S to be microbial. The extracts were freeze-dried prior to combustion for graphitization. Soils collected in 2002 a large pulse of 14CO2 near Oak Ridge (OR), Tennessee. The photosynthetic uptake of the 14CO2 created

  16. Enzyme-mediated labeling of proteins and protein-protein interactions in vitro and in living cells

    E-Print Network [OSTI]

    Slavoff, Sarah Ann

    2010-01-01

    The E. coli biotin ligase enzyme, BirA, has been previously used by the Ting research group for site-specific labeling of peptide-tagged cell surface proteins. We sought to expand the utility of biotin ligase-mediated ...

  17. 1610 IEEE TRANSACTIONS ON IMAGE PROCESSING, VOL. 19, NO. 6, JUNE 2010 A Label Field Fusion Bayesian Model and Its

    E-Print Network [OSTI]

    Mignotte, Max

    1610 IEEE TRANSACTIONS ON IMAGE PROCESSING, VOL. 19, NO. 6, JUNE 2010 A Label Field Fusion Bayesian presents a novel segmentation approach based on a Markov random field (MRF) fusion model which aims reliable and accurate segmentation result. The proposed fusion model is derived from the recently

  18. CFL Labeling Harmonization in the United States, China, Brazil andELI Member Countries: Specifications, Testing, and MutualRecognition

    SciTech Connect (OSTI)

    Fridley, David; Lin, Jiang; Denver, Andrea; Biermayer, Peter; Dillavou, Tyler

    2005-07-20

    This report examines critical differences among energy-efficient labeling programs for CFLs in Brazil, China, the United States, and the seven members of the international Efficient Lighting Initiative (ELI) in terms of technical specifications and test procedures, and review issues related to international harmonization of these standards.

  19. Method and kit for the selective labeling of red blood cells in whole blood with Tc-99m

    DOE Patents [OSTI]

    Srivastava, S.C.; Babich, J.W.; Straub, R.; Richards, P.

    1988-07-05

    Disclosed herein are a method and kit for the preparation of [sup 99m]Tc labeled red blood cells using whole blood in a closed sterile system containing stannous tin in a form such that it will enter the red blood cells and be available for the reduction of technetium. No Drawings

  20. Apparatus and method for preparing oxygen-15 labeled water H.sub.2 [.sup.15 O] in an injectable form for use in positron emission tomography

    DOE Patents [OSTI]

    Ferrieri, Richard A. (Patchogue, NY); Schlyer, David J. (Bellport, NY); Alexoff, David (Westhampton, NY)

    1996-01-09

    A handling and processing apparatus for preparing Oxygen-15 labeled water (H.sub.2 [.sup.15 O]) in injectable form for use in Positron Emission Tomography from preferably H.sub.2 [.sup.15 O] produced by irradiating a flowing gas target of nitrogen and hydrogen. The apparatus includes a collector for receiving and directing a gas containing H.sub.2 [.sup.15 O] gas and impurities, mainly ammonia (NH.sub.3) gas into sterile water to trap the H.sub.2 [.sup.15 O] and form ammonium (NH.sub.4.sup.+) in the sterile water. A device for displacing the sterile water containing H.sub.2 [.sup.15 O] and NH.sub.4.sup.+ through a cation resin removes NH.sub.4.sup.+ from the sterile water. A device for combining the sterile water containing H.sub.2 [.sup.15 O] with a saline solution produces an injectable solution. Preferably, the apparatus includes a device for delivering the solution to a syringe for injection into a patient. Also, disclosed is a method for preparing H.sub.2 [.sup.15 O] in injectable form for use in Positron Emission Tomography in which the method neither requires isotopic exchange reaction nor application of high temperature.

  1. Apparatus and method for preparing oxygen-15 labeled water H{sub 2}[{sup 15}O] in an injectable form for use in positron emission tomography

    DOE Patents [OSTI]

    Ferrieri, R.A.; Schlyer, D.J.; Alexoff, D.

    1996-01-09

    A handling and processing apparatus is revealed for preparing Oxygen-15 labeled water (H{sub 2}[{sup 15}O]) in injectable form for use in Positron Emission Tomography from preferably H{sub 2}[{sup 15}O] produced by irradiating a flowing gas target of nitrogen and hydrogen. The apparatus includes a collector for receiving and directing a gas containing H{sub 2}[{sup 15}O] gas and impurities, mainly ammonia (NH{sub 3}) gas into sterile water to trap the H{sub 2}[{sup 15}O] and form ammonium (NH{sub 4}{sup +}) in the sterile water. A device for displacing the sterile water containing H{sub 2}[{sup 15}O] and NH{sub 4}{sup +} through a cation resin removes NH{sub 4}{sup +} from the sterile water. A device for combining the sterile water containing H{sub 2}[{sup 15}O] with a saline solution produces an injectable solution. Preferably, the apparatus includes a device for delivering the solution to a syringe for injection into a patient. Also, disclosed is a method for preparing H{sub 2}[{sup 15}O] in injectable form for use in Positron Emission Tomography in which the method neither requires isotopic exchange reaction nor application of high temperature. 7 figs.

  2. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    to explore new materials systems for energy storage andof the energy storage materials used, and innovation in newenergy storage design and manufacture to accommodate novel and unconventional materials, new

  3. second gun the steel lining was dispensed with as being

    E-Print Network [OSTI]

    effectually packed the joint,preventing any escape of gas. The vent for "ring ... Let us next examine the resisting ... iron in opposition to an area of the ?uid measuring one square inch ..... 56-15-ng coo/wad export a previously formed steel wing. A. (J-pdr. ... force exerted upon the projectile to overcome its natural vis inertiae...

  4. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    electrolytes for lithium-ion batteries." Journal of PowerElectrolytes for Lithium-Ion Batteries." Advanced materialsstate, plastic, lithium-ion batteries for for low-power

  5. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    Electrically Conductive Oxide Aerogels: New Materials in2003). Electrochemical Properties of Vanadium Oxide Aerogelsand Aerogel Nanocomposites . Journal of Sol-Gel Science and

  6. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    battery include flexible electronics and applications thatthis concept are needed. 8.5 Flexible Electronics Along withthe applications discussed, flexible electronics provides a

  7. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    of microelectromechanical systems (MEMS), elaborate devicescarbon-microelectromechanical systems (C-MEMS) fabrication,autonomous MEMS." Journal of Microelectromechanical Systems

  8. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    microbatteries on a polyimide substrate. The microbatteriesmm by 3 mm trench into polyimide backed with aluminum, whichresistant substrates such as polyimide are also suitable.

  9. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    Management IC for Energy-Scavenged Wireless Sensor Nodes.for Residential Energy Management with Wireless SensorIntroduction to Energy Storage for Miniature Wireless Sensor

  10. Handbook for Handling, Storing, and Dispensing E85

    SciTech Connect (OSTI)

    Not Available

    2008-04-01

    Guidebook contains information about EPAct alternative fuels regulations for fleets, flexible fuel vehicles, E85 properties and specifications, and E85 handling and storage guidelines.

  11. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    Journal of Microelectromechanical Systems 16, no. 4 (JanMEMS." Journal of Microelectromechanical Systems 14, no. 5 (Journal of Microelectromechanical Systems 14, no. 2 (Jan

  12. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    and nanotubes Polyaniline, thiophene- based polymers Hydrous ruthenium oxide Manganese dioxide, nickel

  13. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    Journal of Microelectromechanical Systems 16, no. 4 (JanMEMS." Journal of Microelectromechanical Systems 14, no. 5 (structures." Journal of Microelectromechanical Systems 14,

  14. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    microbatteries with MEMS sensors or energy harvestingR. W. (2009). A MEMS AC current sensor for residential andMEMS Piezoelectric Energy Harvester and a Thick Film Micro Capacitor as a Power Supply System for Wireless Sensor

  15. Dispenser Printed Zinc Microbattery with an Ionic Liquid Gel Electrolyte

    E-Print Network [OSTI]

    Ho, Christine Chihfan

    2010-01-01

    John H. "THIN FILM SOLID ELECTROLYTE SYSTEMS." Thin Solidelectrodes that form solid- electrolyte interface (SEI)include research on solid electrolyte and nano-dimensioned

  16. Handbook for Handling, Storing, and Dispensing E85 | Open Energy

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History View New PagesSustainableGlynnMassachusetts: Energy ResourcesMaine: EnergyHand

  17. Hydrogen Compression, Storage, and Dispensing Cost Reduction Workshop |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing Tool Fits the Bill FinancingDepartment ofPower OutagesWouldHydraulicCompatible

  18. Coriolis Meters for Hydrogen Dispensing Measurement | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based Fuels|ProgramsLakeDepartment ofof EnergyMarketing, Inc. Order

  19. 2013 Hydrogen Compression, Storage, and Dispensing Cost Reduction Workshop

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing ToolInternationalReport FY2014ConferenceofEnergy Oak2013A. Kipp, andFinal Report |

  20. A 0.25 Picoliter Electrostatic MEMS Sideshooter Drop Dispenser.

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield MunicipalTechnicalInformation4563 LLNL Small-scaleCoherent Light Source (Journal Article) |

  1. Hydrogen Compression, Storage, and Dispensing Cost Reduction Workshop

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum12,ExecutiveFinancingR Walls -Hydro-Pac Inc., A High

  2. Dispensing Hydrogen Fuel to Vehicles | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar:IAbout Us|of EnergySmall- Report toDirectivesHydrogen

  3. Alternative Fuels Data Center: Underwriters Laboratories Ethanol Dispenser

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlender PumpVehiclesThe Heat Is on in St. LouisSafety

  4. Alternative Fuels Data Center: Status Update: E85 Dispenser System

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlenderBusiness Case for E85 Fuel

  5. State of Michigan Bulletin Regarding E85 Fuel Dispensers

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center Home PageBlenderBusiness Case forbutton highlightedPublicD,State

  6. Goals and Requirements | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    (E.O.) 13514, E.O. 13423, and related statutory requirements through the Strategic Sustainability Performance Plan (SSPP). These goals and requirements include: E.O. 13514 Goals...

  7. Design requirements formulation : a framework and analysis

    E-Print Network [OSTI]

    Morocz Bazzani, Francisco Andres

    2013-01-01

    This thesis focuses on the early stages of the product development process, during which the set of design requirements is formulated. Given the proven importance of a comprehensive set of design requirements in the market ...

  8. Requirements, possible alternatives & international NEUTRON SCATTERING

    E-Print Network [OSTI]

    Dimeo, Robert M.

    Requirements, possible alternatives & international NEUTRON SCATTERING DETECTORS for Rob Dimeo NIST neutron scattering instruments are the most demanding require background low #12;#12;The Helium-3 Supply Crisis Alternative Techniques to Helium-3 based Detectors for Neutron Scattering Applications

  9. TRANSFORMING USABILITY ENGINEERING REQUIREMENTS INTO SOFTWARE

    E-Print Network [OSTI]

    Carter, Jim

    Chapter N TRANSFORMING USABILITY ENGINEERING REQUIREMENTS INTO SOFTWARE ENGINEERING SPECIFICATIONS Engineers as the basis of analysis and design in software development. While UML is very strong, requirements, software engineering, specifications, unified usability engineering 1. INTRODUCTION While

  10. DOE NEPA Guidance and Requirements- Search Index

    Broader source: Energy.gov [DOE]

    The DOE NEPA Guidance and Requirements - Search Index is a one-stop solution providing you with DOE's Guidance and Requirements documents combined into one file for easy download and use.

  11. Federal Prison Industries-Requirement for Market

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    WWVv .acQnet.govfarlF ACfac200 1-21.i2Qf Effective Date: March 26, 2004 Federal Prison Industries-Requirement for Market 023) This interira rule amends FAR parts 8, Required...

  12. SIENA Customer Problem Statement and Requirements

    SciTech Connect (OSTI)

    L. Sauer; R. Clay; C. Adams; H. Walther; B. Allan; R. Mariano; C. Poore; B. Whiteside; B. Boughton; J. Dike; E. Hoffman; R. Hogan; C. LeGall

    2000-08-01

    This document describes the problem domain and functional requirements of the SIENA framework. The software requirements and system architecture of SIENA are specified in separate documents (called SIENA Software Requirement Specification and SIENA Software Architecture, respectively). While currently this version of the document describes the problems and captures the requirements within the Analysis domain (concentrating on finite element models), it is our intention to subsequent y expand this document to describe problems and capture requirements from the Design and Manufacturing domains. In addition, SIENA is designed to be extendible to support and integrate elements from the other domains (see SIENA Software Architecture document).

  13. UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL WOOD, PLASTICS, & COMPOSITES REQUIREMENTS

    E-Print Network [OSTI]

    Arnold, Jonathan

    UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL WOOD, PLASTICS, & COMPOSITES REQUIREMENTS JANUARY 16, 2015 06 00 00-1 06 00 00 GENERAL WOOD, PLASTICS, & COMPOSITES

  14. UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL THERMAL & MOISTURE PROTECTION REQUIREMENTS ROOF DRAINS & ROOFS

    E-Print Network [OSTI]

    Arnold, Jonathan

    UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL THERMAL & MOISTURE. ii. General #12;UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL

  15. Nanoparticle-based immunosensor with apoferritin templated metallic phosphate label for quantification of phosphorylated acetylcholinesterase

    SciTech Connect (OSTI)

    Du, Dan; Chen, Aiqiong; Xie, Yunying; Zhang, Aidong; Lin, Yuehe

    2011-05-15

    A new sandwich-like electrochemical immunosensor has been developed for quantification of organophosphorylated acetylcholinesterase (OP-AChE), an exposure biomarker of organophosphate pesticides and nerve agents. Zirconia nanoparticles (ZrO2 NPs) were anchored on a screen printed electrode (SPE) to preferably capture OP-AChE adducts by metal chelation with phospho-moieties, which was selectively recognized by lead phosphate-apoferritin labeled anti-AChE antibody (LPA-anti-AChE). The sandwich-like immunoreactions were performed among ZrO2 NPs, OP-AChE and LPA-anti-AChE to form ZrO2/OP-AChE/LPA-anti-AChE complex and the released lead ions were detected on a disposable SPE. The binding affinity was investigated by both square wave voltammetry (SWV) and quartz crystal microbalance (QCM) measurements. The proposed immunosensor yielded a linear response current over a broad OP-AChE concentrations range from 0.05 nM to 10 nM, with detection limit of 0.02 nM, which has enough sensitivity for monitoring of low-dose exposure to OPs. This method avoids the drawback of unavailability of commercial OP-specific antibody as well as amplifies detection signal by using apoferritin encoded metallic phosphate nanoparticle tags. This nanoparticle-based immunosensor offers a new method for rapid, sensitive, selective and inexpensive quantification of phosphorylated adducts for monitoring of OP pesticides and nerve agents exposures.

  16. Production and application of synthetic precursors labeled with carbon-11 and fluorine-18

    SciTech Connect (OSTI)

    Ferrieri, R.A.

    2001-04-02

    It is evident from this chapter that there is enormous flexibility both in the selection of the nature of the radioisotope and ways to generate it, as well as in the selection of the labeling precursor to appropriately attach that radioisotope to some larger biomolecule of interest. The arsenal of radiolabeling precursors now available to the chemist is quite extensive, and without a doubt will continue to grow as chemists develop new ones. However, the upcoming years will perhaps reflect a greater effort in refining existing methods for preparing some of those precursors that are already available to us. For example, the use of solid-phase reactions to accomplish in a single step what would normally take several using conventional solvent-based reactions has already been shown to work in many occasions. The obvious advantage here is that processes become more amenable to system automation thus affording greater reliability in day-to-day operations. There are perhaps other technologies in science that have yet to be realized by the chemist in the PET laboratory that could provide a similar or even a greater benefit. One only needs to be open to new ideas, and imaginative enough to apply them to the problems at hand.

  17. I-131 labelled peanut lectin renal kinetics in cis-platin induced tubular toxicity in dogs

    SciTech Connect (OSTI)

    Boniface, G.R.; Willans, D.J.; Noujaim, A.A.

    1985-05-01

    Quantitative I-131 labelled Peanut lectin (I-131-PNA) renal clearance was determined in dogs before and after a 5 day single cycle cis-platinum chemotherapy regimen (0.5mg/Kg/day). Results were statistically compared with E.R.P.F. (I-131-Hippuran), G.F.R. (Tc-99m-DTPA), and serum biochemistry and correlated with histopathology. I-131-PNA clearance was significantly reduced in all dogs 5 days after cessation of cis-platinum treatment (mean ..delta..S% = 71.3%) and similar reductions in the gamma camera derived renogram peak were demonstrated (mean ..delta..S% = 65.8%). E.R.P.F. was noted to drop by a minor degree (mean ..delta..S% = 20.9%) post treatment. G.F.R. was diminished (mean ..delta..S% = 46.6%) and serum creatinine elevated (mean ..delta..S% = 42.7%) in all dogs compared to their pretreatment values. Histopathology demonstrated variable degrees of tubular toxicity ranging from mild to severe. The degree of change of the I-131-PNA values was significantly greater than that predicted by indicators of glomerular function. These results suggest that quantitative renal tubular imaging may be useful in the determination of tubular toxicity.

  18. Acting Globally: Potential Carbon Emissions Mitigation Impacts from an International Standards and Labelling Program

    SciTech Connect (OSTI)

    McNeil, Michael A; Letschert, Virginie E.; de la Rue du Can, Stephane; Egan, Christine

    2009-05-29

    This paper presents an analysis of the potential impacts of an international initiative designed to support and promote the development and implementation of appliances standards and labelling programs throughout the world. As part of previous research efforts, LBNL developed the Bottom Up Energy Analysis System (BUENAS), an analysis framework that estimates impact potentials of energy efficiency policies on a global scale. In this paper, we apply this framework to an initiative that would result in the successful implementation of programs focused on high priority regions and product types, thus evaluating the potential impacts of such an initiative in terms of electricity savings and carbon mitigation in 2030. In order to model the likely parameters of such a program, we limit impacts to a five year period starting in 2009, but assume that the first 5 years of a program will result in implementation of 'best practice' minimum efficiency performance standards by 2014. The 'high priority' regions considered are: Brazil, China, the European Union,India, Mexico and the United States. The products considered are: refrigerators, air conditioners, lighting (both fluorescent and incandescent), standby power (for consumer electronics) and televisions in the residential sector, and air conditioning and lighting in commercial buildings. In 2020, these regions and enduses account for about 37percent of global residential electricity and 29percent of electricity in commercial buildings. We find that 850Mt of CO2 could be saved in buildings by 2030 compared to the baseline forecast.

  19. Detection of atomic spin labels in a lipid bi-layer using a single-spin nanodiamond probe

    E-Print Network [OSTI]

    Kaufmann, Stefan; Hall, Liam T; Perunicic, Viktor; Senn, Philipp; Steinert, Steffen; McGuinness, Liam P; Johnson, Brett C; Ohshima, Takeshi; Caruso, Frank; Wrachtrup, Joerg; Scholten, Robert E; Mulvaney, Paul; Hollenberg, Lloyd C L

    2013-01-01

    Magnetic field fluctuations arising from fundamental spins are ubiquitous in nanoscale biology, and are a rich source of information about the processes that generate them. However, the ability to detect the few spins involved without averaging over large ensembles has remained elusive. Here we demonstrate the detection of gadolinium spin labels in an artificial cell membrane under ambient conditions using a single-spin nanodiamond sensor. Changes in the spin relaxation time of the sensor located in the lipid bilayer were optically detected and found to be sensitive to near-individual proximal gadolinium atomic labels. The detection of such small numbers of spins in a model biological setting, with projected detection times of one second, opens a new pathway for in-situ nanoscale detection of dynamical processes in biology.

  20. Determination of the internalization pathway of photoluminescent nanodiamonds in mammalian cells for biological labeling and optimization of the ?uorescent yield

    E-Print Network [OSTI]

    Faklaris, Orestis; Irinopoulou, Theano; Tauc, Patrick; Girard, Hugues; Gesset, Celine; Senour, Mohamed; Thorel, Alain; Arnault, Jean-Charles; Boudou, Jean-Paul; Curmi, Patrick A; Treussart, Franois

    2009-01-01

    Diamond nanoparticles have been recently used as new ?uorescent labels in cells. Their emission relies on color centers embedded in the diamond matrix. In this work we compare the photoluminescence of a single color center embedded in a 30 nm diameter nanodiamond to that to a single dye molecule and demonstrate the perfect photostability of the color centers. We also compare the photoluminescence properties of nanodiamonds prepared under different conditions in order to ?nd the optimal parameters to achieve a high ?uorescence yield. We use these photoluminescent nanodiamonds for HeLa cell labeling and investigate their uptake mechanism. On the one hand by immunostaining the endocytotic vesicles and on the other by transmission electron microscopy observations we study the localization of nanodiamonds in cells. Moreover, by blocking selectively different endocytotic mechanisms we unravel their internalization pathway. We ?nd that nanodiamonds enter the cells by receptor-mediated endocytosis. The results of thi...

  1. Requirement of B-Raf, C-Raf, and A-Raf for the growth and survival of mouse embryonic stem cells

    SciTech Connect (OSTI)

    Guo, Wenjing; Hao, Baixia; Wang, Qian; Lu, Yingying; Yue, Jianbo, E-mail: jbyue@me.com

    2013-11-01

    Extracellular signal-regulated kinases (ERKs) have been implicated to be dispensable for self-renewal of mouse embryonic stem (ES) cells, and simultaneous inhibition of both ERK signaling and glycogen synthase kinase 3 (GSK3) not only allows mouse ES cells to self-renew independent of extracellular stimuli but also enables more efficient derivation of nave ES cells from mouse and rat strains. Interestingly, some ERKs stay active in mouse ES cells which are maintained in regular medium containing leukemia inhibitory factor (LIF) and bone morphogenetic protein (BMP). Yet, the upstream signaling for ERK activation and their roles in mouse ES cells, other than promoting or priming differentiation, have not been determined. Here we found that mouse ES cells express three forms of Raf kinases, A-Raf, B-Raf, and C-Raf. Knocking-down each single Raf member failed to affect the sustained ERK activity, neither did A-Raf and B-Raf double knockdown or B-Raf and C-Raf double knockdown change it in ES cells. Interestingly, B-Raf and C-Raf double knockdown, not A-Raf and B-Raf knockdown, inhibited the maximal ERK activation induced by LIF, concomitant with the slower growth of ES cells. On the other hand, A-Raf, B-Raf, and C-Raf triple knockdown markedly inhibited both the maximal and sustained ERK activity in ES cells. Moreover, Raf triple knockdown, similar to the treatment of U-0126, an MEK inhibitor, significantly inhibited the survival and proliferation of ES cells, thereby compromising the colony propagation of mouse ES cells. In summary, our data demonstrate that all three Raf members are required for ERK activation in mouse ES cells and are involved in growth and survival of mouse ES cells. - Highlights: ?Mouse ES (mES) cells express all three Raf members, A-Raf, B-Raf, and C-Raf. ?Leukemia inhibitory factor (LIF) temporally activates ERKs in mES cells. ?B-Raf and C-Raf are required for LIF-induced maximal ERKs activity in mES cells. ?All Raf members are required for LIF-induced sustained ERK activity in mES cells. ?All Raf members are required the survival and proliferation of mES cells.

  2. International Review of Frameworks for Impact Evaluation of Appliance Standards, Labeling, and Incentives

    E-Print Network [OSTI]

    Zhou, Nan

    2014-01-01

    et al. 2009 SRC et al. 2001 IPMVP 2002, updated 2011 VreulsRequired Deemed values, IPMVP approach, or statisticalVerification Protocol (IPMVP) vii Table of Content Executive

  3. A nanoparticle label/immunochromatographic electrochemical biosensor for rapid and sensitive detection of prostate-specific antigen

    SciTech Connect (OSTI)

    Lin, Ying-Ying; Wang, Jun; Liu, Guodong; Wu, Hong; Wai, Chien M.; Lin, Yuehe

    2008-06-15

    We present a nanoparticle (NP) label/immunochromatographic electrochemical biosensor (IEB) for rapid and sensitive detection of prostate-specific antigen (PSA) in human serum. This IEB integrates the immunochromatographic strip with the electrochemical detector for transducing quantitative signals. The NP label, made of CdSe@ZnS, serves as a signal-amplifier vehicle. A sandwich immunoreaction was performed on the immunochromatographic strip. The captured NP labels in the test zone were determined by highly sensitive stripping voltammetric measurement of the dissolved metallic component (cadmium) with a disposable-screen-printed electrode, which is embedded underneath the membrane of the test zone. Experimental parameters (e.g., immunoreaction time, the amount of anti-PSA-NP conjugations applied) and electrochemical detection conditions (e.g., preconcentration potential and time) were optimized using this biosensor for PSA detection. The analytical performance of this biosensor was evaluated with serum PSA samples according to the figure-of-merits (e.g., dynamic range, reproducibility, and detection limit). The results were validated with enzyme-linked immunosorbent assay (ELISA) and show high consistency. It is found that this biosensor is very sensitive with the detection limit of 0.02 ng/mL PSA and is quite reproducible. This method is rapid, clinically accurate, and less expensive than other diagnosis tools for PSA; therefore, this IEB coupled with a portable electrochemical analyzer shows great promise for simple, sensitive, quantitative point-of-care testing of disease-related protein biomarkers.

  4. Savings estimates for the United States Environmental Protection Agency?s ENERGY STAR voluntary product labeling program

    SciTech Connect (OSTI)

    Sanchez, Marla Christine; Sanchez, Marla Christine; Brown, Richard; Homan, Gregory; Webber, Carrie

    2008-06-03

    ENERGY STAR is a voluntary energy efficiency-labeling program operated jointly by the United States Department of Energy and the United States Environmental Protection Agency (US EPA). Since the program inception in 1992, ENERGY STAR has become a leading international brand for energy efficient products. ENERGY STAR's central role in the development of regional, national, and international energy programs necessitates an open process whereby its program achievements to date as well as projected future savings are shared with committed stakeholders. Through 2006, US EPA?S ENERGY STAR labeled products saved 4.8 EJ of primary energy and avoided 82 Tg C equivalent. We project that US EPA?S ENERGY STAR labeled products will save 12.8 EJ and avoid 203 Tg C equivalent over the period 2007-2015. A sensitivity analysis examining two key inputs (carbon factor and ENERGY STAR unit sales) bounds the best estimate of carbon avoided between 54 Tg C and 107 Tg C (1993 to 2006) and between 132 Tg C and 278 Tg C (2007 to 2015).

  5. UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL MECHANICAL REQUIREMENTS (HVAC)

    E-Print Network [OSTI]

    Arnold, Jonathan

    UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS GENERAL MECHANICAL REQUIREMENTS (HVAC) JANUARY 16, 2015 23 00 001 23 00 00 GENERAL MECHANICAL REQUIREMENTS (HVAC) 1. GENERAL A. Related sections: i. 00 00 07 Design Professional Design Process Requirements ii. 00 00

  6. Core Science Requirement Final Document Page 1 THE CORE SCIENCE REQUIREMENT and

    E-Print Network [OSTI]

    Frey, Jesse C.

    Core Science Requirement Final Document Page 1 THE CORE SCIENCE REQUIREMENT and MENDEL SCIENCE EXPERIENCE COURSES Core requirement of 2 semesters of science with laboratory; requirement to be met by the end of the sophomore year Rationale Science literacy is an integral part of the intellectual

  7. Mendel Science Experience Requirements | Version 2 | 29 April 2015 The Core Science Requirement and Mendel Science

    E-Print Network [OSTI]

    Frey, Jesse C.

    Mendel Science Experience Requirements | Version 2 | 29 April 2015 The Core Science Requirement and Mendel Science Experience Courses Core requirement: 2 semesters of science with laboratory; requirement) Rationale Science literacy is an integral part of the intellectual credentials of an educated, informed

  8. AMINO ACID SYNTHESIS IN PHOTO-SYNTHESIZING SPINACH CELLS. EFFECTS OF AMMONIA ON POOL SIZES AND RATES OF LABELING FROM 14co2

    E-Print Network [OSTI]

    Larsen, Peder Olesen

    2013-01-01

    EFFECTS OF AMMONIA ON POOL SIZES AND RATES OF LABELING FROMmetabolically active and passive pools of these amino acids.of added ammonia on ing, pool sizes, and specific activi pro

  9. Requirements Flowdown and Graded Approach to QA

    Office of Environmental Management (EM)

    Plan Project Focus Area Task and Description Deliverable Project Area 1: Requirements Flow Down Task 1.9 - Complete White Paper covering procurement QA process flow diagram...

  10. Federal / State Legislative & Regulatory Changes Required for...

    Office of Environmental Management (EM)

    Required for Introduction of E15 More Documents & Publications Improving Ethanol-Gasoline Blends by Addition of Higher Alcohols High Octane Fuels Can Make Better Use of...

  11. Transmission Reassignment Reporting Requirement - April 2, 2014

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Interconnection Notices Rates Standards of Conduct Tariff TF Web Based Training Transmission Reassignment Reporting Requirement This notice serves as a reminder to transmission...

  12. NBP RFI: Communications Requirements- Honeywell Responses To...

    Broader source: Energy.gov (indexed) [DOE]

    (e.g., we do not consider communications necessary for phasor measurements, substation SCADA, protective relaying, etc.) NBP RFI: Communications Requirements- Honeywell Responses...

  13. Bioinformatics and Genomics Degree Requirements Booklet

    E-Print Network [OSTI]

    dePamphilis, Claude

    Bioinformatics and Genomics Degree Requirements Booklet Fall 2011 #12;- -2 Contents Course Bioinformatics and Genomics Curriculum ------------------------------------------------------ 8 General--------------------------------------------------------------------- 14 #12;- -3 Bioinformatics and Genomics Option (BG

  14. NERSC/DOE FES Requirements Workshop Presentations

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Presentations Workshop Presentations Large Scale Computing and Storage Requirements for Fusion Energy Sciences An FES ASCR NERSC Workshop August 3-4, 2010 Sort by: Default |...

  15. NERSC/DOE ASCR Requirements Workshop Logistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Logistics Workshop Logistics Large Scale Computing and Storage Requirements for Advanced Scientific Computing Research January 5-6, 2011 Location The workshop will be held at...

  16. NERSC/DOE FES Requirements Workshop Logistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Logistics Workshop Logistics Large Scale Computing and Storage Requirements for Fusion Energy Sciences An FES ASCR NERSC Workshop August 3-4, 2010 Goals This workshop is being...

  17. NERSC/DOE NP Requirements Workshop Logistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hotel Hotel Arrangements Large Scale Computing and Storage Requirements for Nuclear Physics May 26-27, 2011 Location The workshop will be held at Hyatt Regency Bethesda One...

  18. Biosafety Facilities - DOE Directives, Delegations, and Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    5, Biosafety Facilities by David Freshwater Functional areas: Defense Nuclear Facility Safety and Health Requirement, Safety and Security, The Guide assists DOENNSA field elements...

  19. Transport of fluorescently labeled hydroxyapatite nanoparticles in saturated granular media at environmentally relevant concentrations of surfactants

    SciTech Connect (OSTI)

    Wang, Dengjun; Su, Chuming; Liu, Chongxuan; Zhou, Dongmei

    2014-05-01

    Hydroxyapatite nanoparticle (nHAP) is being used to remediate soils and aquifers contaminated with metals and radionuclides; however, the mobility of nHAP is still poorly understood in subsurface granular environments. In this study, transport and retention kinetics of alizarin red S (ARS)-labeled nHAP were investigated in water-saturated quartz sand at low concentrations of surfactants: sodium dodecyl benzene sulfonate (SDBS, an anionic surfactant, 050 mg L1) and cetyltrimethylammonium bromide (CTAB, a cationic surfactant, 05 mg L1). Both surfactants were found to have a marked effect on the electrokinetic properties of ARS-nHAP and, consequently, on their transport and retention behaviors. Transport of nanoparticles (NPs) increased significantly with increasing SDBS concentration, largely because of enhanced colloidal stability and reduced aggregate size arising from enhanced electrostatic, osmotic, and elastic-steric repulsions between ARS-nHAP and sand grains. Conversely, transport decreased significantly in the presence of increasing CTAB concentrations due to reduced surface charge and consequential enhanced aggregation of the NPs. Osmotic and elastic-steric repulsions played only a minor role in enhancing the colloidal stability of ARS-nHAP in the presence of CTAB. Retention profiles of ARS-nHAP exhibited hyperexponential-shapes (decreasing rates of retention with increasing distance) for all conditions tested, and became more pronounced as CTAB concentration increased. The phenomenon was attributed to the aggregation and ripening of ARS-nHAP in the presence of surfactants, particularly CTAB. Overall, the present study suggests that surfactants at environmentally relevant concentrations may be an important consideration in employing nHAP for engineered in-situ remediation of certain metals and radionuclides in contaminated soils and aquifers.

  20. Final report-98-ERI-003 identification of population with lifetime 41Ca-labeled skeletons

    SciTech Connect (OSTI)

    Freeman, S P

    1999-02-25

    In 1997 we first postulated the existence of a special human population that had had their skeletons inadvertently isotopically adulterated in the past. We theorized that the population, and the necessary LLNL accelerator mass spectrometer (AMS) measurement technology, would prove a significant resource in the fight to combat osteoporosis. This LDRD project was to establish such. The project was significantly successful in its initial year, but was not renewed for another and the research is now ended at LLNL. We proposed a three-year program to (1) confirm the magnitude and extent of historical 41 Ca dosing, (2) exactly characterize the long-term 41 Ca signal by comparing it with conventional measurements of skeletal health, and (3) demonstrate the utility of the historically labeled population in evaluating an actual potential therapy for osteoporosis. However, rather than investigate historical records to learn the identity of those inadvertently dosed, find them, and if possible enroll them into a new protocol, this project was to be particularly efficient by making use of a multiyear archive of samples from original, inadvertent 41 Ca-dosing experiments at Creighton University in Omaha, Nebraska. Because the subjects had been dosed in conventional studies of calcium kinetics, much important correlating historical data would also be available for comparison. Measurements of contemporary urine samples specifically provided for this project by selected identified subjects would follow. We discovered a second archive at the University of Texas Southwestern Medical Center. This is potentially a better source of material as the samples were generated in numerous historical evaluations of actual osteoporosis therapies in which 41 Ca-impure radiotracers were used. The therapies might now powerfully be retrospectively evaluated, both to contribute to our understanding of the therapies and to highlight the potential of the use of 41 Ca tracer and LLNL measurement.

  1. Giant Magnetoresistive Sensors and Magnetic Labels for Chip-Scale Detection of Immunosorbent Assays

    SciTech Connect (OSTI)

    Rachel Lora Millen

    2005-12-17

    The combination of giant magnetoresistive sensors, magnetic labeling strategies, and biomolecule detection is just beginning to be explored. New readout methods and assay formats are necessary for biomolecules detection to flourish. The work presented in this dissertation describes steps toward the creation of a novel detection method for bioassays utilizing giant magnetoresistive sensors as the readout method. The introduction section contains a brief review of some of the current methods of bioassay readout. The theoretical underpinnings of the giant magnetoresistive effect are also discussed. Finally, the more prominent types of giant magnetoresistive sensors are described, as well as their complicated fabrication. Four data chapters follow the introduction; each chapter is presented as a separate manuscript, either already published or soon to be submitted. Chapter 1 presents research efforts toward the production of a bioassay on the surface of a gold-modified GMR sensor. The testing of this methodology involved the capture of goat a-mouse-coated magnetic nanoparticles on the mouse IgG-modified gold surface. The second, third and fourth chapters describe the utilization of a self-referenced sample stick for scanning across the GMR sensor. The sample stick consisted of alternating magnetic reference and bioactive gold addresses. Chapter 2 is concerned with the characterization of both the scanning readout method and the binding and detection of streptavidin-coated magnetic particles to a biotinylated surface. Chapter 3 advances the sample stick readout with the use of the system for detection of a sandwich immunoassay with rabbit IgG proteins. Finally, simultaneous detection of three IgG proteins is demonstrated in Chapter 4. The dissertation is concluded with a brief summary of the research presented and a discussion of the possible future applications and direction of this work.

  2. WASTES II model storage requirements benchmark testing

    SciTech Connect (OSTI)

    Shay, M.R.; Walling, R.C.; Altenhofen, M.K.

    1986-09-01

    A study was conducted to benchmark results obtained from using the Waste System Transportation and Economic Simulation - Version II (WASTES II) model against information published in the ''Spent Fuel Storage Requirements'' report (DOE/RL-84-1). The WASTES model was developed by PNL for use in evaluating the spent-fuel storage and transportation requirements and costs for the US Department of Energy (DOE). The ''Spent Fuel Storage Requirements'' report is issued annually by the DOE and provides both historical/projected spent fuel inventory data and storage requirements data based on information supplied directly from utilities. The objective of this study is to compare the total inventory and storage requirements documented in the ''Spent Fuel Storage Requirements'' report with similar data that results from use of the WASTES model. Three differences have been identified as a result of benchmark testing. Two minor differences are present in the total inventory projected and the equivalent metric tons of uranium of spent fuel requiring storage. These differences result from the way reinserted spent fuel is handled and the methods used to calculate mass equivalents. A third difference is found in the storage requirements for the case that uses intra-utility transshipment. This discrepancy is due to the Oyster Creek reactor, which is shown to not require additional storage in the Spent Fuel Storage Requirements report, even though there is no destination reactor of the same type within its utility. The discrepancy was corrected soon after the 1984 ''Spent Fuel Storage Requirements report was issued and does not appear in more recent documents (DOE/RL-85-2).

  3. WATER SOLUBLE VITAMIN REQUIREMENTS OF SILVER SALMON

    E-Print Network [OSTI]

    WATER SOLUBLE VITAMIN REQUIREMENTS OF SILVER SALMON Marine Biological Laboratory FEB !) ~iy;)9, Commissioner WATER-SOLUBLE VITAMIN REQUIREMENTS OF SILVER SALMON By John A. Coates* and John E. Halver Western, John A Wiiti'i-sohilile vitamin ivcjuireineiits of silver sahnon, by John A. CoiUes and John E. Ilalver

  4. RESEARCH ARTICLE Adaptive Resistance in Bacteria Requires

    E-Print Network [OSTI]

    Cluzel, Philippe

    RESEARCH ARTICLE Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps. PLoS ONE 10, Cambridge, Massachusetts, United States of America * max@fis.unam.mx Abstract Adaptive resistance emerges

  5. SECTION GS1020 CONSTRUCTION CODE REQUIREMENTS

    E-Print Network [OSTI]

    Zhang, Yuanlin

    101, Life Safety Code; 5. National Fire Protection Association Codes and Standards; 6. ANSI/ASME A17SECTION GS1020 ­ CONSTRUCTION CODE REQUIREMENTS PART 1 - GENERAL 1.1 RELATED DOCUMENTS A. Drawings includes the following: 1. Construction code requirements for all construction at Texas Tech University. 1

  6. EARTH SCIENCES Lower-Division Requirements

    E-Print Network [OSTI]

    Constable, Steve

    2012-2013 EARTH SCIENCES Lower-Division Requirements Math 20A_____ 20B_____ 20C_____ 20D (BILD 3) _____ SIO 50* _____ Group A: Earth Science Upper-Division Core Requirements (all courses _____ Introduction to Geophysics SIO 104 _____ Paleobiology and History of Life* Group B: Upper-Division Earth

  7. Conduct of Operations Requirements for DOE Facilities

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1990-07-09

    "To provide requirements and guidelines for Departmental Elements, including the National Nuclear Security Administration (NNSA), to use in developing directives, plans, and/or procedures relating to the conduct of operations at DOE facilities. The implementation of these requirements and guidelines should result in improved quality and uniformity of operations. Change 2, 10-23-2001. Canceled by DOE O 422.1.

  8. A MULTIMEDIA APPROACH TO REQUIREMENTS CAPTURE

    E-Print Network [OSTI]

    Stevens, Scott M.

    OF ELECTRICAL AND ELECTRONICS ENGINEERS, INC. I EEE COMPUTER SOCIETY #12;A Multimedia Approach to Requirements. Stevens Reprinted from the PROCEEDINGS OF THE FIRST INTERNATIONAL CONFERENCE ON REQUIREMENTS ENGINEERING Capture and Modeling David P. Wood Michael G. Christel Scott M. Stevens Software Engineering Institute

  9. Safety Requirements and Fault Trees using Retrenchment

    E-Print Network [OSTI]

    Banach, Richard

    this initial model has been created, the elicitation of safety requirements yields a fresh set of criteria are applied, the information linking the design and the safety assessment phases is often carried outSafety Requirements and Fault Trees using Retrenchment R. Banach and R. Cross Computer Science

  10. Biochemistry and Molecular Biology -Bachelor of Science (SMBCUG) Total Credits Required: 128 Major Requirements -62 credits Concentration Requirements -29 credits

    E-Print Network [OSTI]

    Biochemistry and Molecular Biology - Bachelor of Science (SMBCUG) Total Credits Required: 128 Major University Chemistry II AND 3 CH4995 Undergraduate Research in Biochemistry OR 6 CH1161 University Chemistry

  11. Smart gun technology requirements preliminary report

    SciTech Connect (OSTI)

    Weiss, D.R.; Brandt, D.J.; Tweet, K.D.

    1995-05-01

    Goal of the Smart Gun Technology project is to eliminate the capability of an unauthorized user from firing a law enforcement officer`s firearm by implementing user-recognizing-and-authorizing surety technologies. This project is funded by the National Institute of Justice. This document reports the projects first objective: to find and document the requirements for a user-recognizing-and-authorizing firearm technology that law enforcement officers will value. This report details the problem of firearm takeaways in law enforcement, the methodology used to develop the law enforcement officers` requirements, and the requirements themselves.

  12. Quality Assurance Source Requirements Traceability Database

    SciTech Connect (OSTI)

    MURTHY, R., NAYDENOVA, A., DEKLEVER, R., BOONE, A.

    2006-01-30

    At the Yucca Mountain Project the Project Requirements Processing System assists in the management of relationships between regulatory and national/industry standards source criteria, and Quality Assurance Requirements and Description document (DOE/R W-0333P) requirements to create compliance matrices representing respective relationships. The matrices are submitted to the U.S. Nuclear Regulatory Commission to assist in the commission's review, interpretation, and concurrence with the Yucca Mountain Project QA program document. The tool is highly customized to meet the needs of the Office of Civilian Radioactive Waste Management Office of Quality Assurance.

  13. Optical manufacturing requirements for an AVLIS plant

    SciTech Connect (OSTI)

    Primdahl, K.; Chow, R.; Taylor, J.R.

    1997-07-14

    A uranium enrichment plant utilizing Atomic Vapor Laser Isotope Separation (AVLIS) technology is currently being planned. Deployment of the Plant will require tens of thousands of commercial and custom optical components and subsystems. The Plant optical system will be expected to perform at a high level of optical efficiency and reliability in a high-average-power-laser production environment. During construction, demand for this large number of optics must be coordinated with the manufacturing capacity of the optical industry. The general requirements and approach to ensure supply of optical components is described. Dynamic planning and a closely coupled relationship with the optics industry will be required to control cost, schedule, and quality.

  14. HTGR Industrial Application Functional and Operational Requirements

    SciTech Connect (OSTI)

    L. E. Demick

    2010-08-01

    This document specifies the functional and performance requirements to be used in the development of the conceptual design of a high temperature gas-cooled reactor (HTGR) based plant supplying energy to a typical industrial facility. These requirements were developed from collaboration with industry and HTGR suppliers over the preceding three years to identify the energy needs of industrial processes for which the HTGR technology is technically and economically viable. The functional and performance requirements specified herein are an effective representation of the industrial sector energy needs and an effective basis for developing a conceptual design of the plant that will serve the broadest range of industrial applications.

  15. Progress towards Managing Residential Electricity Demand: Impacts of Standards and Labeling for Refrigerators and Air Conditioners in India

    SciTech Connect (OSTI)

    McNeil, Michael A.; Iyer, Maithili

    2009-05-30

    The development of Energy Efficiency Standards and Labeling (EES&L) began in earnest in India in 2001 with the Energy Conservation Act and the establishment of the Indian Bureau of Energy Efficiency (BEE). The first main residential appliance to be targeted was refrigerators, soon to be followed by room air conditioners. Both of these appliances are of critical importance to India's residential electricity demand. About 15percent of Indian households own a refrigerator, and sales total about 4 million per year, but are growing. At the same time, the Indian refrigerator market has seen a strong trend towards larger and more consumptive frost-free units. Room air conditioners in India have traditionally been sold to commercial sector customers, but an increasing number are going to the residential sector. Room air conditioner sales growth in India peaked in the last few years at 20percent per year. In this paper, we perform an engineering-based analysis using data specific to Indian appliances. We evaluate costs and benefits to residential and commercial sector consumers from increased equipment costs and utility bill savings. The analysis finds that, while the BEE scheme presents net benefits to consumers, there remain opportunities for efficiency improvement that would optimize consumer benefits, according to Life Cycle Cost analysis. Due to the large and growing market for refrigerators and air conditioners in India, we forecast large impacts from the standards and labeling program as scheduled. By 2030, this program, if fully implemented would reduce Indian residential electricity consumption by 55 TWh. Overall savings through 2030 totals 385 TWh. Finally, while efficiency levels have been set for several years for refrigerators, labels and MEPS for these products remain voluntary. We therefore consider the negative impact of this delay of implementation to energy and financial savings achievable by 2030.

  16. UGA DESIGN & CONSTRUCTION SUPPLEMENTAL GENERAL REQUIREMENTS & STANDARDS DOOR AND FRAMES

    E-Print Network [OSTI]

    Arnold, Jonathan

    have welded joints. B. Knock down door frames (factory pre-finished steel door frames which exception below for UGA Housing). F. For UGA Housing Only (New Construction) i. Design Professional for tested, labeled door construction for Project. 6) Lite/lock conflicts: follow door manufacturer

  17. February 5, 2008 RE: California Energy Commission Annual Reporting Requirements

    E-Print Network [OSTI]

    as anything other than net system power must disclose these sources as specific purchases,ii which are subject SPECIFIC PURCHASE CLAIMS Annual Report: Power Source Disclosure Program March 3, 2008 SB 1305 Annual Report. The Annual Power Content Label Retail providers that claim specific purchases must submit an Annual Power

  18. MATH MINOR REQUIREMENTS Minimum units required: 18 (2012-2014 catalogs)

    E-Print Network [OSTI]

    Fatkullin, Ibrahim

    MATH MINOR REQUIREMENTS Minimum units required: 18 (2012-2014 catalogs) (at least 3 units must be completed at UA) Minimum minor GPA: 2.00 Course Work Requirements: Complete both: o MATH 122A/B or 125: Calculus I o MATH 129: Calculus II Choose two courses from: o MATH 313: Introduction to Linear Algebra

  19. Cell detachment and label-free cell sorting using modulated surface acoustic waves (SAW) in droplet-based microfluidics

    E-Print Network [OSTI]

    Bussonnire, Adrien; Baudoin, Michael; Bou-Matar, Olivier; Grandbois, Michel; Charette, Paul; Renaudin, Alan

    2014-01-01

    We present a droplet-based surface acoustic wave (SAW) system designed to viably detach biological cells from a surface and sort cell types based on differences in adhesion strength (adhesion contrast), without the need to label cells with molecular markers. The system uses modulated SAW to generate pulsatile flows in the droplets and efficiently detach the cells, thereby minimizing SAW excitation power and exposure time. As a proof-of-principle, the system is shown to efficiently sort HEK 293 from A7r5 cells based on adhesion contrast. Results are obtained in minutes with sorting purity and efficiency reaching 97 % and 95 %, respectively.

  20. The Access Almanac: Solar Parking Requirements

    E-Print Network [OSTI]

    Shoup, Donald

    2012-01-01

    getting solar power from our parking lots. ? A C C E S STHE ACCESS ALMANAC Solar Parking Requirements DONALD SHOUP SC E I N T H E S U N on parking lots surrounding commercial