Sample records for discipline structural biology

  1. Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife Biology, Ecology, and Management

    E-Print Network [OSTI]

    Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife CONTENTS ABSTRACT

  2. Bacterial Community Structure in Geographically Distributed Biological

    E-Print Network [OSTI]

    Alvarez-Cohen, Lisa

    Bacterial Community Structure in Geographically Distributed Biological Wastewater Treatment of the microbial communities within biological wastewater treatment reactors is incomplete due to limitations microbial community composition in five biological wastewater treatment reactors in China and the United

  3. BE.442 Molecular Structure of Biological Materials, Fall 2005

    E-Print Network [OSTI]

    Zhang, Shuguang, Dr.

    Basic molecular structural principles of biological materials. Molecular structures of various materials of biological origin, including collagen, silk, bone, protein adhesives, GFP, self-assembling peptides. Molecular ...

  4. Increasing Public Involvement in Structural Biology

    E-Print Network [OSTI]

    Baker, David

    --often referred to as citizen science--provides a means of engaging people's skills, rather than just for the public to get actively involved in structural biology research? Citizen science projects can require areas for citizen science as structural problems both are amenable to human spatial-reasoning skills

  5. Structural Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our Instagram Secretary900SteepStrengthening northern NewStructuralSpecificity

  6. 2004 Reversible Associations in Structure & Molecular Biology

    SciTech Connect (OSTI)

    Edward Eisenstein Nancy Ryan Gray

    2005-03-23T23:59:59.000Z

    The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

  7. Quantitative Languages for Complex Systems Applied to Biological Structure

    E-Print Network [OSTI]

    representations of the system. We illustrate the development of such languages using the structure of Drosophila this problem as well as to promote the study of complex systems as a systematic discipline, we seek to develop, life cycle stages, mutant abnormalities, gene expression patterns, genetic interactions, etc. In order

  8. 2010 Diffraction Methods in Structural Biology

    SciTech Connect (OSTI)

    Dr. Ana Gonzalez

    2011-03-10T23:59:59.000Z

    Advances in basic methodologies have played a major role in the dramatic progress in macromolecular crystallography over the past decade, both in terms of overall productivity and in the increasing complexity of the systems being successfully tackled. The 2010 Gordon Research Conference on Diffraction Methods in Structural Biology will, as in the past, focus on the most recent developments in methodology, covering all aspects of the process from crystallization to model building and refinement, complemented by examples of structural highlights and complementary methods. Extensive discussion will be encouraged and it is hoped that all attendees will participate by giving oral or poster presentations, the latter using the excellent poster display area available at Bates College. The relatively small size and informal atmosphere of the meeting provides an excellent opportunity for all participants, especially younger scientists, to meet and exchange ideas with leading methods developers.

  9. Designing a service science discipline with discipline

    E-Print Network [OSTI]

    Glushko, Robert J.

    in what IBM began to call, in late 2004, service science, management and engineering--or simply SSME. 3 in information and computing technol- ogy, industrial engineering, business strategy, eco- nomics, lawDesigning a service science discipline with discipline & R. J. Glushko This paper relates our

  10. Administering Workforce Discipline

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2014-10-27T23:59:59.000Z

    To provide requirements and responsibilities for administering workforce discipline that includes disciplinary, adverse, and alternative corrective actions in the Department of Energy (DOE).

  11. MAD ANALYSIS OF FHIT STRUCTURAL BIOLOGY CENTER*

    E-Print Network [OSTI]

    Kemner, Ken

    , plants, and humans, are involved in some critical and ubiquitous biochemical pathway that remains National Laboratory ¥ àElectronics & Computing Technologies Division, Argonne National Laboratory ¥ ¤Howard transcript exists in the cell with one full-length copy of the gene. This study provides the first structure

  12. Departments of Chemistry and Pharmacology Center for Structural Biology

    E-Print Network [OSTI]

    Meiler, Jens

    Scoring Matrices Dot Product Alignment Dynamic Programming Algorithm BLAST Algorithm Homework Assignment #12;Structural Biology After the Human Genome Project 6 December 2011 Jens Meiler 3 #12;Millions? Gap penalties can be modeled as linear depending on the length: penalty It is more likely

  13. Biologic

    E-Print Network [OSTI]

    Louis H. Kauffman

    2002-04-03T23:59:59.000Z

    In this paper we explore the boundary between biology and the study of formal systems (logic). In the end, we arrive at a summary formalism, a chapter in "boundary mathematics" where there are not only containers but also extainers >protein folding and the basic structure of the Temperley Lieb algebra at the foundations of topological invariants of knots and links.

  14. Work Force Discipline

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1983-03-23T23:59:59.000Z

    The order provides guidance and procedures and states responsibilities for maintaining work force discipline in DOE. Chg 1, dated 3-11-85; Chg 2, dated 1-6-86; Chg 3, dated 3-21-89; Chg 4, dated 8-2-90; Chg 5, dated 3-9-92; Chg 6, dated 8-21-92, cancels Chg 5.

  15. Regulation 2: Student Discipline REGULATION 2: STUDENT DISCIPLINE

    E-Print Network [OSTI]

    Sussex, University of

    Regulation 2: Student Discipline 6 REGULATION 2: STUDENT DISCIPLINE 1. Definitions In this Regulation: The University means the University of Sussex. Council means Council of the University. Senate to the regulations of the affiliated institution, and excluding students in attendance at the Brighton and Sussex

  16. Structural and biological studies of bone morphogenetic protein-15

    E-Print Network [OSTI]

    McMahon, Heather Eileen

    2007-01-01T23:59:59.000Z

    homolog, GDF-9; both proteins lack the fourth of seventhe recombinant protein with this mutation lacks biologicallacks biological activity and, intriguingly, the mutant protein

  17. Procedure for developing biological input for the design, location, or modification of water-intake structures

    SciTech Connect (OSTI)

    Neitzel, D.A.; McKenzie, D.H.

    1981-12-01T23:59:59.000Z

    To minimize adverse impact on aquatic ecosystems resulting from the operation of water intake structures, design engineers must have relevant information on the behavior, physiology and ecology of local fish and shellfish. Identification of stimulus/response relationships and the environmental factors that influence them is the first step in incorporating biological information in the design, location or modification of water intake structures. A procedure is presented in this document for providing biological input to engineers who are designing, locating or modifying a water intake structure. The authors discuss sources of stimuli at water intakes, historical approaches in assessing potential/actual impact and review biological information needed for intake design.

  18. Microfluidics in structural biology: smaller, faster. . . better Carl Hansen and Stephen R Quake

    E-Print Network [OSTI]

    Hansen, Carl L.

    Microfluidics in structural biology: smaller, faster. . . better Carl Hansen and Stephen R Quake Microfluidic technologies promise unprecedented savings in cost and time through the integration of complex of this vision a reality, facilitating the first large-scale integration of microfluidic plumbing with biological

  19. Departments of Chemistry and Pharmacology Center for Structural Biology

    E-Print Network [OSTI]

    Meiler, Jens

    ;6 December 2011 Jens Meiler 2 Schedule for Lecture 7 De Novo Protein Fold Prediction with Rosetta) Protein Folding Problem Holy Grail of Comp. Struct. Biology Given a protein's AA sequence, what is its 3 than 1010 years old. Cyrus Levinthal's paradox of protein folding,1968. 6 December 2011 Jens Meiler

  20. Polarized Neutron in Structural Biology Present and Future Outlook

    SciTech Connect (OSTI)

    Zhao, Jinkui [ORNL; Robertson, Lee [ORNL; Herwig, Kenneth W [ORNL; Crabb, Don [University of Virginia

    2013-01-01T23:59:59.000Z

    Hydrogen has a strong polarization-dependent neutron scattering cross section. This property has been exploited in the study of soft matters, especially biological macromolecules. When a polarized neutron beam is scattered off a polarized hydrogenous sample, the otherwise large hydrogen incoherent cross section is drastically reduced while the coherent signal is significantly increased. Past experiments have demonstrated the potentials and benefits of polarized neutron scattering from soft materials. The main technical challenge of polarized neutron scattering from biological matters lies at sample polarization. Dynamic nuclear polarization is a proven yet rather sophisticated technique. Its complexity is one of the main reasons for the technique's slow adoption. The future of polarized neutron scattering in biology may rest largely in neutron protein crystallography. Polarization of protein crystals is much easier to accomplish, since protein crystals are typically rather small (<<1 mm) and only require small and easy- to-operate polarization apparatuses. In addition, the high resolution nature of neutron protein crystallography means that we will be able to study individual atoms using the polarized neutron scattering technique.

  1. Size structuring of planktonic communities : biological rates and ecosystem dynamics

    E-Print Network [OSTI]

    Taniguchi, Darcy Anne Akiko

    2013-01-01T23:59:59.000Z

    and nutrient enriched ecosystems. Limnology and Oceanographyin the pelagic ecosystem. Helgol. Wiss. Meeresunters. 30:Size-structured planktonic ecosystems: constraints, controls

  2. Turn Scanning 133 From: Methods in Molecular Biology, vol. 168: Protein Structure, Stability, and Folding

    E-Print Network [OSTI]

    Ponder, Jay

    Turn Scanning 133 133 From: Methods in Molecular Biology, vol. 168: Protein Structure, Stability, and Folding Edited by: K. P. Murphy Humana Press Inc., Totowa, NJ 7 Turn Scanning: Experimental extended structures. Here we present the use of turn scanning as an experimental method for assessing

  3. Structural and Computational Studies of Small Organic and Biological Molecules

    E-Print Network [OSTI]

    Lozano-Casal, Patricia

    2006-01-01T23:59:59.000Z

    to investigate the energetics of the crystal structures: i.e., the sublimation, lattice and proton transfer energies, as well as the energies of the individual hydrogen bonds, in order to relate the structural changes observed by experiment. A new computational...

  4. Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiological andU.S.Biology

  5. Structural Biology DOI: 10.1002/anie.200900481

    E-Print Network [OSTI]

    de Groot, Bert

    Molecules on a Protein­Ligand Interaction** Christian M. Stegmann, Daniel Seeliger, George M. Sheldrick) In the apo CypGPPIase structure, Arg115 is in an open conformation (d, major conformation shown). Mesh: s

  6. Are We Closing the School Discipline Gap?

    E-Print Network [OSTI]

    Losen, Daniel; Hodson, Cheri; Keith II, Michael A; Morrison, Katrina; Belway, Shakti

    2015-01-01T23:59:59.000Z

    D.J. , (Ed). Closing the School Discipline Gap: EquitableBooth, E.A. (2011). Breaking schools rules: A statewidestudy of how school discipline relates to students success

  7. Biological Macromolecular Structures Data from the RCSB Protein Data Bank (RCSB PDB)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The Research Collaboratory for Structural Bioinformatics (RCSB) is a non-profit consortium that works to improve understanding of the function of biological systems through the study of the 3-D structure of biological macromolecules. The RCSB PDB is one of three sites serving as deposition, data processing, and distribution sites of the Protein Data Bank Archive. Each site provides its own view of the primary data, thus providing a variety of tools and resources for the global community. RCSB is also the official keeper for the PDB archive, with sole access authority to the PDB archive directory structure and contents. The RCSB PDB Information Portal for Biological Macromolecular Structures offers online tools for search and retrieval, for visualizing structures, for depositing, validating, or downloading data, news and highlights, a discussion forum, and links to other areas of related research. The PDB archive is a repository of atomic coordinates and other information describing proteins and other important biological macromolecules. Structural biologists use methods such as X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy to determine the location of each atom relative to each other in the molecule. They then deposit this information, which is then annotated and publicly released into the archive by the wwPDB. Results can be viewed as 3-D images or models.

  8. EDITOR OF CONFERENCE PROCEEDINGS: 17. Health Monitoring of Structural and Biological Systems 2011 , Ed. T. Kundu, Pub.

    E-Print Network [OSTI]

    Wong, Pak Kin

    EDITOR OF CONFERENCE PROCEEDINGS: 17. Health Monitoring of Structural and Biological Systems 2011/NDE, March 7-10, 2011, San Diego, California, Vol. 7984, 2011 16. Health Monitoring of Structural 9780819475558, 2009. 14. Health Monitoring of Structural and Biological Systems 2008 , Ed. T. Kundu, Pub. SPIE

  9. Structure and Dynamics of Biological Systems Research Team: James E. Evans, Daniel E. Perea, Xiao-Ying Yu, Zihua Zhu

    E-Print Network [OSTI]

    Structure and Dynamics of Biological Systems Research Team: James E. Evans, Daniel E. Perea, Xiao for atomic resolution structure determination; observe dynamics using a pump-probe regime. Dynamic TEM probe tomography to interrogate the structure and dynamics of biological systems

  10. DOE EPSCoR Initiative in Structural and computational Biology/Bioinformatics

    SciTech Connect (OSTI)

    Wallace, Susan S.

    2008-02-21T23:59:59.000Z

    The overall goal of the DOE EPSCoR Initiative in Structural and Computational Biology was to enhance the competiveness of Vermont research in these scientific areas. To develop self-sustaining infrastructure, we increased the critical mass of faculty, developed shared resources that made junior researchers more competitive for federal research grants, implemented programs to train graduate and undergraduate students who participated in these research areas and provided seed money for research projects. During the time period funded by this DOE initiative: (1) four new faculty were recruited to the University of Vermont using DOE resources, three in Computational Biology and one in Structural Biology; (2) technical support was provided for the Computational and Structural Biology facilities; (3) twenty-two graduate students were directly funded by fellowships; (4) fifteen undergraduate students were supported during the summer; and (5) twenty-eight pilot projects were supported. Taken together these dollars resulted in a plethora of published papers, many in high profile journals in the fields and directly impacted competitive extramural funding based on structural or computational biology resulting in 49 million dollars awarded in grants (Appendix I), a 600% return on investment by DOE, the State and University.

  11. Amyloid -Protein Fibrillogenesis STRUCTURE AND BIOLOGICAL ACTIVITY OF PROTOFIBRILLAR INTERMEDIATES*

    E-Print Network [OSTI]

    Benedek, George B.

    with damaged neuropil and blood vessels contain abun- dant fibrils formed by the amyloid -protein (A ). Fibrils discovered a novel intermediate in the pathway of A fibril formation, the amyloid protofibril (Walsh, D. M); 2) have a secondary structure characteristic of amyloid fibrils; 3) appear as beaded chains

  12. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)

    SciTech Connect (OSTI)

    Eisenberg, David S.

    2008-07-15T23:59:59.000Z

    The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission of the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages. The development of publicly accessible, web-based servers, including the HOTPATCH server, the ProKnow Server and the SAVEs server. All of these are accessible from the home page of the Institute. Advancing the science of bioenergy, in the laboratories of the Principal Investigators of the Institute, including the laboratories of Shimon Weiss, James Liao, James Bowie, Todd Yeates, Rob Gunsalus.

  13. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

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  14. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposedPAGESafetyTed5, 2015 Independent StatisticsThe

  15. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposedPAGESafetyTed5, 2015 Independent StatisticsTheThe

  16. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposedPAGESafetyTed5, 2015 Independent StatisticsTheTheThe

  17. STRUCTURE-MECHANICAL PROPERTY RELATIONSHIPS IN A BIOLOGICAL CERAMIC-POLYMER COMPOSITE: NACRE

    E-Print Network [OSTI]

    Aksay, Ilhan A.

    171 STRUCTURE-MECHANICAL PROPERTY RELATIONSHIPS IN A BIOLOGICAL CERAMIC-POLYMER COMPOSITE: NACRE, a laminated ceramic- polymer biocompositefound in seashell. Four-pointbending strength and three-point bend and ultramicrotomedsections with and without the intactarago- nite platelets. We found that the organic matrix is indeed

  18. NERSC HPSS Storage by Scientific Discipline

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Storage by Scientific Discipline Troubleshooting IO Resources for Scientific Applications at NERSC Optimizing IO performance on the Lustre file system IO Formats Science...

  19. The Puzzle of Discipline: An Examination of African American Disproportionality in School Discipline and Student Performance

    E-Print Network [OSTI]

    Butler, Bettie Ray

    2012-07-16T23:59:59.000Z

    The intent of this study was to systematically investigate the relationship between African American disproportionality in school discipline which is the overrepresentation of students for exclusionary discipline practices (i.e., out-of-school...

  20. Software Engineering, an established Accreditable Engineering Discipline

    E-Print Network [OSTI]

    Szabados, Barna

    Software Engineering, an established Accreditable Engineering Discipline By B.Szabados, P.Eng, Mc of the Canadian Engineering Accreditation Board (CEAB), as well as at a workshop at the NCDEAS meeting in September 1997. 1. INTRODUCTION In the late seventies, the discipline of Computer Engineering has evolved

  1. www.sbc.anl.gov The Structural Biology Center enables the atomic-scale study of macromolecular

    E-Print Network [OSTI]

    Kemner, Ken

    systems using very small crystal samples. It also offers the most efficient data collection and structure to synchrotron data collection W H O W E A R E Supported by the U.S. Department of Energy, the Structural Biologywww.sbc.anl.gov The Structural Biology Center enables the atomic-scale study of macromolecular

  2. Structure of a Designed, Right-Handed Coiled-Coil Tetramer Containing All Biological Amino Acids

    SciTech Connect (OSTI)

    Sales, M.; Plecs, J.J.; Holton, J.M.; Alber, T.

    2009-06-04T23:59:59.000Z

    The previous design of an unprecedented family of two-, three-, and four-helical, right-handed coiled coils utilized nonbiological amino acids to efficiently pack spaces in the oligomer cores. Here we show that a stable, right-handed parallel tetrameric coiled coil, called RH4B, can be designed entirely using biological amino acids. The X-ray crystal structure of RH4B was determined to 1.1 {angstrom} resolution using a designed metal binding site to coordinate a single Yb{sup 2+} ion per 33-amino acid polypeptide chain. The resulting experimental phases were particularly accurate, and the experimental electron density map provided an especially clear, unbiased view of the molecule. The RH4B structure closely matched the design, with equivalent core rotamers and an overall root-mean-square deviation for the N-terminal repeat of the tetramer of 0.24 {angstrom}. The clarity and resolution of the electron density map, however, revealed alternate rotamers and structural differences between the three sequence repeats in the molecule. These results suggest that the RH4B structure populates an unanticipated variety of structures.

  3. Structural and biological mimicry of protein surface recognition by [alpha/beta]-peptide foldamers

    SciTech Connect (OSTI)

    Horne, W. Seth; Johnson, Lisa M.; Ketas, Thomas J.; Klasse, Per Johan; Lu, Min; Moore, John P.; Gellman, Samuel H.; (Cornell); (UW)

    2009-10-05T23:59:59.000Z

    Unnatural oligomers that can mimic protein surfaces offer a potentially useful strategy for blocking biomedically important protein-protein interactions. Here we evaluate an approach based on combining {alpha}- and {beta}-amino acid residues in the context of a polypeptide sequence from the HIV protein gp41, which represents an excellent testbed because of the wealth of available structural and biological information. We show that {alpha}/{beta}-peptides can mimic structural and functional properties of a critical gp41 subunit. Physical studies in solution, crystallographic data, and results from cell-fusion and virus-infectivity assays collectively indicate that the gp41-mimetic {alpha}/{beta}-peptides effectively block HIV-cell fusion via a mechanism comparable to that of gp41-derived {alpha}-peptides. An optimized {alpha}/{beta}-peptide is far less susceptible to proteolytic degradation than is an analogous {alpha}-peptide. Our findings show how a two-stage design approach, in which sequence-based {alpha} {yields} {beta} replacements are followed by site-specific backbone rigidification, can lead to physical and biological mimicry of a natural biorecognition process.

  4. STATE OF THE DISCIPLINE POVERTY, RACE, AND

    E-Print Network [OSTI]

    Shyy, Wei

    STATE OF THE DISCIPLINE POVERTY, RACE, AND ANTIPOVERTY POLICY BEFORE AND AFTER HURRICANE KATRINA1 response toward those affected, it did not lead to a serious discourse about the nature of poverty earnings are lower and poverty rates are higher for African Americans than for Whites, the economic

  5. Behaviors That Result in Employee Discipline

    E-Print Network [OSTI]

    Oliver, Douglas L.

    would much rather you be productive and happy on the job. Most employers have resources to help is not punishment. The goal of discipline is to deter a re- peat of the performance problem (quality of work your concerns confidentially with an employee assistance professional can help. Human resources is also

  6. DISCIPLINE OF RADIATION THERAPY SAFETY DOCUMENT

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    DISCIPLINE OF RADIATION THERAPY SAFETY DOCUMENT Contents Page 1. Health & Safety arrangements 1 Inspection 1.4 Hazard Reporting 1.5 Security in College 1.6 Out of Hours Working 1.7 Management of Work.7 Management of Work-related Stress Those experiencing symptoms of work-related stress should raise this matter

  7. Biology Meets Engineering: The Structural Mechanics of Fossil and Extant Shark Teeth

    E-Print Network [OSTI]

    Motta, Philip J.

    . Whitenack,1 * Daniel C. Simkins Jr.,2 and Philip J. Motta1 1 Department of Integrative Biology, University

  8. The mechanical properties of biological structures and their materials are among the most fundamental of the numerous

    E-Print Network [OSTI]

    Denny, Mark

    The mechanical properties of biological structures and their materials are among the most hydrodynamic forces, which might be expected to place strong constraints on material properties and morphology be the case for a falling rock climber jerked to a halt by a safety rope, where the climber's kinetic energy

  9. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work...

  10. DISCIPLINE AND TERMINATION POLICY Employees covered by this policy

    E-Print Network [OSTI]

    DISCIPLINE AND TERMINATION POLICY Employees covered by this policy This policy applies to all non to discipline, suspend with or without pay, or terminate employees for just cause. Just cause includes to discipline or termination for just cause, the University reserves the right to demote, suspend or terminate

  11. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect (OSTI)

    Galitski, Timothy P.

    2008-04-01T23:59:59.000Z

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  12. Structure and mechanics of the spasmoneme, a biological spring within the protozoan Vorticella convallaria

    E-Print Network [OSTI]

    France, Danielle Cook

    2007-01-01T23:59:59.000Z

    Molecular springs have recently emerged as the basis for the fastest and most powerful movements at the cellular level in biology. The spasmoneme of the protozoan, Vorticella convallaria, is a model molecular spring, relying ...

  13. High performance computing and communications Grand Challenges program: Computational structural biology. Final report, August 15, 1992--January 14, 1997

    SciTech Connect (OSTI)

    Solomon, J.E.

    1997-10-02T23:59:59.000Z

    The Grand Challenge project consists of two elements: (1) a hierarchical methodology for 3D protein structure prediction; and (2) development of a parallel computing environment, the Protein Folding Workbench, for carrying out a variety of protein structure prediction/modeling computations. During the first three years of this project the author focused on the use of selected proteins from the Brookhaven Protein Data Base (PDB) of known structures to provide validation of the prediction algorithms and their software implementation, both serial and parallel. Two proteins in particular have been selected to provide the project with direct interaction with experimental molecular biology. A variety of site-specific mutagenesis experiments are performed on these two proteins to explore the many-to-one mapping characteristics of sequence to structure.

  14. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology and imple- #12;Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture

  15. Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife Using Combined Snowpack and

    E-Print Network [OSTI]

    Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture, BCMOF 1 Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture

  16. Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

  17. Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife CONTENTS

  18. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife Extension Note

  19. Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife Assessing Habitat Quality of

    E-Print Network [OSTI]

    Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife CONTENTS

  20. Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife Relationships between Elevation and Slope

    E-Print Network [OSTI]

    Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

  1. 1132 nature structural biology volume 6 number 12 december 1999 To be active, proteins must fold into well-defined three-dimen-

    E-Print Network [OSTI]

    Matouschek, Andreas

    precursor proteins normally lack all structure during import11, but some proteins assume their native formarticles 1132 nature structural biology volume 6 number 12 december 1999 To be active, proteins must fold into well-defined three-dimen- sional structures. However, unfolding of proteins is also

  2. Synchrotron Radiation Circular Dichroism (SRCD) Spectroscopy: An Emerging Method in Structural Biology for Examining Protein Conformations and Protein Interactions

    SciTech Connect (OSTI)

    Wallace, B.A.; Sutherland, J.; Gekko, K.; Hoffmann, S. V.; Lin, Y.-H.; Tao, Y.; Wien, F.; Janes, R. W.

    2011-09-01T23:59:59.000Z

    Circular dichroism (CD) spectroscopy is a well-established technique in structural biology. The use of synchrotron radiation as an intense light source for these measurements extends the applications possible using lab-based instruments. In recent years, there has been a major growth in synchrotron radiation circular dichroism (SRCD) beamlines worldwide, including ones at the NSLS, ISA, SRS, HiSOR, BSRF, NSRRC, SOLEIL, Diamond, TERAS, BESSYII, and ANKA synchrotrons. Through the coordinated efforts of beamline scientists and users at these sites, important proof-of-principle studies have been done enabling the method to be developed for novel and productive studies on biological systems. This paper describes the characteristics of SRCD beamlines and some of the new types of applications that have been undertaken using these beamlines.

  3. fll INTRODUCTION Solid mechanics is a fundamental discipline which, in

    E-Print Network [OSTI]

    generation technologies such as fusion, nuclear and gas turbine power, aerospace and surface trans- nortation, solid mechanics is a central discipline for hydrocarbon resource extraction by drilling, hydraulic

  4. DRAFT - DOE O 333.1, Administering Work Force Discipline

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    To provide requirements and responsibilities for administering workforce discipline that includes disciplinary, adverse, and alternative corrective actions in the Department of Energy (DOE).

  5. Biology 494 Biology Internship

    E-Print Network [OSTI]

    Wurtele, Eve Syrkin

    Biology 494 Biology Internship Guidelines The Biology Program encourages students to seek out and participate in internship opportunities that have a clear biological focus. Internships may be arranged may receive credit in Biology 494 (Biology Internship) for participation in internships, regardless

  6. 2006 Reversible Associations in Structural and Molecular Biology Conference-January 15-20, 2006

    SciTech Connect (OSTI)

    Gary Ackers

    2007-04-10T23:59:59.000Z

    Many biological processes are carried out through the formation of macromolecular complexes, ranging from the simplest conformational organization to the most sophisticated interactions among complexes themselves. Reversible associations generate specific local conformations, active site configurations, and subunit--subunit interfaces, and encompass larger scale quaternary rearrangements and dissociation events. Assembled complexes exhibit properties different from those of component parts, such that 'the whole is greater than the sum of the parts', resulting in biological functioning of the assembly. This Gordon Research Conference brings together researchers from what may appear to be disparate fields with the common focus of applying quantitative kinetic and thermodynamic analysis to reversible macromolecular interactions. This conference will include the following session topics: (1) Protein design in evolution and recognition; (2) Emerging technologies; (3) Single molecule mechanics; (4) Nucleic acid/protein recognition; (5) Lipid/protein recognition; (6) Protein switches and networks; (7) Advances in classic technologies; (8) Ligand/macromolecule complexes and drug design; and (9) Selected student oral presentations; all from the perspective of reversibly associating systems. A wide array of techniques are typically covered, from single molecule to computational methods, chromatography and analytical ultracentrifugation, spectroscopic dynamics and titration calorimetry. The quantitative analysis of assembled complexes demonstrates that these biologically important functions depend not just upon a single part of the molecule, but on the coordination brought about by the ensemble of interactions. Applications from graduate students and young postdoctoral scientists are welcomed. A selection of short talks will be invited from students presenting posters.

  7. Cycle time variability for a network under two queueing disciplines

    E-Print Network [OSTI]

    Vasquez Pariente, Marta Irene

    1996-01-01T23:59:59.000Z

    A network of three single-server queues is investigated. Performance of two queueing disciplines is compared on the basis of the mean and variance of the network cycle time. The two queueing disciplines are first-in-system first-out (FISFO...

  8. news and views 482 nature structural biology volume 8 number 6 june 2001

    E-Print Network [OSTI]

    Sali, Andrej

    inactivation by acid) not seen in the original structures. The con- clusions of this study thus take us one step further toward understanding the ability of H. pylori to resist acid and perhaps the development proteins111. The first essential step in structural genomics is the selection of tar- get protein

  9. Cryoelectron Microscopy as a Functional Instrument for Systems Biology, Structural Analysis & Experimental Manipulations with Living Cells. A comprehensive review of the current works

    E-Print Network [OSTI]

    Gradov, Oleg V

    2015-01-01T23:59:59.000Z

    The aim of this paper is to give an introductory review of the cryoelectron microscopy as a complex data source for the most of the system biology branches, including the most perspective non-local approaches known as "localomics" and "dynamomics". A brief summary of various cryoelectron mi-croscopy methods and corresponding system biological ap-proaches is given in the text. The above classification can be considered as a useful framework for the primary comprehen-sions about cryoelectron microscopy aims and instrumental tools. We do not discuss any of these concepts in details, but merely point out that their methodological complexity follows only from the structure-functional complexity of biological systems which are investigated in this manner. We also postu-late that one can employ some of the cryoelectron microscopic techniques not only for observation, but also for modification and structural refunctionalization of some biological and similar soft matter objects and microscopic samples. In other world...

  10. 606 nature structural biology volume 8 number 7 july 2001 Unfolding individual

    E-Print Network [OSTI]

    Leuba, Sanford

    N. The assembled single chromatin fiber was subjected to stretching by controlled movement of one of the beads underlying these structural transformations remain elusive. The develop- ment of an applied tension. This extract, containing core histones and nonhistone proteins but lacking somatic linker histones, assembles

  11. Electrical Engineering is a diverse discipline encompassing computer and information

    E-Print Network [OSTI]

    Rohs, Remo

    70 ELECTRICAL Electrical Engineering is a diverse discipline encompassing computer and information environmental engineering and manufacturing to semiconductors and telecommunications. The Electrical Engineering Technology and the Signal and Image Processing institute. PROGRAMS AVAILABLE Electrical Engineering

  12. Electrical Engineering is a diverse discipline encompassing computer and information

    E-Print Network [OSTI]

    Rohs, Remo

    70 ELECTRICAL Electrical Engineering is a diverse discipline encompassing computer and information environmental engineering and manufacturing to semiconductors and telecommunications. The Electrical Engineering Technology and the Signal and Image Processing institute. PROGRAMS AVAILABLE Electrical Engineering Bachelor

  13. FINAL REPORT: DOE CONTRACT NUMBER FG0205ER64026 Biological Neutron Scattering: A Collaboration with the Oak Ridge Center for Structural Molecular Biology

    SciTech Connect (OSTI)

    Jill Trewhella

    2011-01-12T23:59:59.000Z

    The overarching goal of this project was to promote applications of small-angle scattering in structural molecular biology by providing model examples of cutting edge applications that demonstrate the unique capabilities and potential of the DOE national user facilities at Oak Ridge, especially the newly commissioned BioSANS. The approach taken was three-fold: (1) to engage in high impact collaborative research projects that would benefit from small-angle neutron scattering to both demonstrate the power of the technique while expanding the potential user community; (2) to provide access to scattering facilities established at the University of Utah to as broad a set of researchers as possible to increase the expertise in small-angle scattering generally; and (3) to develop new methods and tools for small-angle scattering. To these ends, three major research collaborations were pursued that resulted in a significant body of published work where neutron scattering and contrast variation played a major role. These major collaborations involved studies of protein complexes involved in (1) bacterial transcription regulation and adaptive response (a DOE/BER priority area); (2) regulation of cardiac muscle; and (3) neuronal disorders. In addition, to broaden the impact of the project, smaller collaborative efforts were supported that used either small-angle X-ray or neutron scattering. Finally, the DOE supported facilities at the University of Utah were made available to researchers on a service basis and a number of independent groups took advantage of this opportunity. In all of this work, there was an emphasis on the training of students and post docs in scattering techniques, and a set of publications (a book chapter, a review, and an encyclopedia article) were produced to guide the non-specialist potential user of scattering techniques in successful applications of the techniques. We also developed a suite of user friendly web-based computational tools currently being accessed world-wide by researchers as an aid in neutron scattering data interpretation. In all, these collaborative projects and resulted in 29 original refereed journal articles published between 2005 and 2010 and engaged groups from at least 14 Universities (10 US, 4 international) and 3 National Laboratories (2 US, 1 international). An important final initiative from this project was to begin a process for international community agreement on a set of standards for the publication of biomolecular small-angle scattering data. This initiative is being championed with the International Union of Crystallography and has engaged a number of Journal Editors and is a very important step in the maturing of this now burgeoning field.

  14. Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife Using Airphotos to Interpret

    E-Print Network [OSTI]

    Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture March 2004 Research Section, Coast Forest Region, BCMOF 1 Research Disciplines: Ecology ~ Geology

  15. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology-748-1331. mdeact@shaw.ca #12;Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology

  16. Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife

    E-Print Network [OSTI]

    Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology.for.gov.bc.ca/vancouvr/research/research_index.htm #12;Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture

  17. Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology.for.gov.bc.ca/vancouvr/research/research_index.htm #12;Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture

  18. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology, BC, V9J 1G4 #12;Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology

  19. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology Rd., Black Creek, BC, V9J 1G4 #12;Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology

  20. Biologically Inspired Synthesis Route to Three-Dimensionally Structured Inorganic Thin Films

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Schwenzer, Birgit; Morse, Daniel E.

    2008-01-01T23:59:59.000Z

    Inorganic thin films (hydroxide, oxide, and phosphate materials) that are textured on a submicron scale have been prepared from aqueous metal salt solutions at room temperature using vapor-diffusion catalysis. This generic synthesis approach mimics the essential advantages of the catalytic and structure-directing mechanisms observed for the formation of silica skeletons of marine sponges. Chemical composition, crystallinity, and the three-dimensional morphology of films prepared by this method are extremely sensitive to changes in the synthesis conditions, such as concentrations, reaction times, and the presence and nature of substrate materials. Focusing on different materials systems, the reaction mechanism for the formation ofmorethese thin films and the influence of different reaction parameters on the product are explained.less

  1. Division of Biological and Medical Research research summary 1984-1985

    SciTech Connect (OSTI)

    Barr, S.H. (ed.)

    1985-08-01T23:59:59.000Z

    The Division of Biological and Medical Research at Argonne National Laboratory conducts multidisciplinary research aimed at defining the biological and medical hazards to man from energy technologies and new energy options. These technically oriented studies have a strong base in fundamental research in a variety of scientific disciplines, including molecular and cellular biology, biophysics, genetics, radiobiology, pharmacology, biochemistry, chemistry, environmental toxicology, and epidemiology. This research summary is organized into six parts. The first five parts reflect the Divisional structure and contain the scientific program chapters, which summarize the activities of the individual groups during the calendar year 1984 and the first half of 1985. To provide better continuity and perspective, previous work is sometimes briefly described. Although the summaries are short, efforts have been made to indicate the range of research activities for each group.

  2. Cryoelectron Microscopy as a Functional Instrument for Systems Biology, Structural Analysis & Experimental Manipulations with Living Cells. A comprehensive review of the current works

    E-Print Network [OSTI]

    Oleg V. Gradov; Margaret A. Gradova

    2015-01-18T23:59:59.000Z

    The aim of this paper is to give an introductory review of the cryoelectron microscopy as a complex data source for the most of the system biology branches, including the most perspective non-local approaches known as "localomics" and "dynamomics". A brief summary of various cryoelectron mi-croscopy methods and corresponding system biological ap-proaches is given in the text. The above classification can be considered as a useful framework for the primary comprehen-sions about cryoelectron microscopy aims and instrumental tools. We do not discuss any of these concepts in details, but merely point out that their methodological complexity follows only from the structure-functional complexity of biological systems which are investigated in this manner. We also postu-late that one can employ some of the cryoelectron microscopic techniques not only for observation, but also for modification and structural refunctionalization of some biological and similar soft matter objects and microscopic samples. In other worlds, we start with the cryoelectron microscopy as a tool for the sys-tem biology and progress to its applying as an instrument for system biology and functional biomimetics; i.e. "system cryobi-ology" goes over into "synthetic cryobiology" or "cryogenic biomimetics". All these conclusions can be deduced from the most recent works of the latest years, including just submitted foreign papers. This article provides an up-to-date description of the conceptual basis for the novel view on the computational cryoelectron microscopy (in silico) approaches and the data mining principles which lie at the very foundation of modern structural analysis and reconstruction.

  3. Iosif Vaisman Department of Bioinformatics and Computational Biology

    E-Print Network [OSTI]

    Vaisman, Iosif

    Iosif Vaisman Department of Bioinformatics and Computational Biology Email: ivaisman@gmu.edu BINF agreed on the following definitions of bioinformatics and computational biology recognizing STRUCTURAL BIOLOGY COMPUTATIONAL MOLECULAR BIOLOGY BIOINFORMATICS GENOMICS STRUCTURAL GENOMICS PROTEOMICS

  4. Sustainable Future Stevens students bridged disciplines to advance

    E-Print Network [OSTI]

    Yang, Eui-Hyeok

    Building a Sustainable Future Stevens students bridged disciplines to advance sustainable living which collects and analyzes data to preserve energy and teach occupants to live more sustainably of our sustainable future. 4stevens.edu/ecohabit (1) Ecohabit was the only competition house that used

  5. Towards a Discipline of Geospatial Distributed Event Based Systems

    E-Print Network [OSTI]

    Heaton, Thomas H.

    Towards a Discipline of Geospatial Distributed Event Based Systems Annie Liu Computer Science, Caltech 1200 E California Blvd Pasadena, CA 91125, USA mani@cms.caltech.edu ABSTRACT A geospatial system is one in which the state space in- cludes one, two or three-dimensional space and time. A geospatial

  6. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology Hudson and Axel Anderson KEYWORDS: Water management, Coastal watersheds, hydrological modeling CITATIONPractice. ResearchSection,Coast ForestRegion, BCMOF,Nanaimo, BC. Extension Note EN-022. EN-022 Hydrology March 2006

  7. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology,Tsitika Watershed.Research Section,CoastForest Region,BCMOF, Nanaimo, BC. Extension Note EN-021. EN-021 Hydrology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife Extension Note EN-021 March 2006 Forest Research

  8. Penn State Multi-Discipline Tribology Group and Energy Institute Studies.

    SciTech Connect (OSTI)

    Perez, Joseph

    2001-08-05T23:59:59.000Z

    This presentation is a summary of the current research activities on fuels and lubricants in the Multi-discipline Tribology group and the engine test group in the Combustion Laboratory of the Pennsylvania State University. The progress areas discussed in this summary include those found in Table 1. Table 1. RESEARCH AREAS: Diesel Engine Emission Reduction; Oxygenated Fuels; Improved Friction Fuels; Vegetable Oil Lubricants; Extended Drain Lubricants; Effect of Chemical Structure on Friction and Wear. The research is of interest either directly or indirectly to the goal of this workshop, diesel engine emissions reduction. The current projects at Penn State in the areas listed above will be discussed.

  9. structural biology | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular Science Computing Facility: Quiet Wing Science Theme: Biosystem Dynamics & Design Terrestrial & Subsurface Ecosystems Energy Materials & Processes Atmospheric...

  10. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our Instagram Secretary900SteepStrengthening northernDeterminationScience Highlights

  11. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our Instagram Secretary900SteepStrengthening northernDeterminationScience

  12. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our Instagram Secretary900SteepStrengthening northernDeterminationScienceTraining

  13. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of ScienceandMesa del SolStrengthening a solid ... Strengthening a solid

  14. Physics Meets Biology (LBNL Summer Lecture Series)

    ScienceCinema (OSTI)

    Chu, Steve [Director, LBNL

    2011-04-28T23:59:59.000Z

    Summer Lecture Series 2006: If scientists could take advantage of the awesomely complex and beautiful functioning of biologys natural molecular machines, their potential for application in many disciplines would be incalculable. Nobel Laureate and Director of the Lawrence Berkeley National Laboratory Steve Chu explores Possible solutions to global warming and its consequences.

  15. NATURE STRUCTURAL & MOLECULAR BIOLOGY VOLUME 16 NUMBER 12 DECEMBER 2009 1267 A RT I C L E S

    E-Print Network [OSTI]

    Chou, James

    of BM2 is also a coiled-coil tetramer, and its unusually large electrostatic dipole moment suggests-coil tetramer with a packing angle of about -37 (Fig. 1a). The tetramer has a well 1Department of Biological

  16. Use of computer to analyze and archive biological data (sequence and structural information) on a large scale

    E-Print Network [OSTI]

    Park, Sheldon

    classification #12;Given a structure, identify the regions of secondary structure DSSP, Stride, DEFINE of the Swiss Institute of Bioinformatics National Center for Biotechnology Information National Library to structural classification Distance alignment matrix (DALI) Combinatorial extension (CE) Sequential

  17. For immediate release --October 1, 2014 New media practices converge across disciplines

    E-Print Network [OSTI]

    Hossain, Shahadat

    For immediate release -- October 1, 2014 New media practices converge across disciplines Students entering the field of new media might not be aware of all the ways new media tools are being used across disciplines

  18. Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Technical Report Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife CONTENTS SUMMARY

  19. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife Extension Note EN-007

  20. Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture Systems ~ Wildlife Silvicultural Treatments for Enhancing

    E-Print Network [OSTI]

    Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife CONTENTS EXECUTIVE SUMMARY

  1. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItem Not Found Item Not Found The itemAIR SEPARATIONscience, and technology for

  2. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGerman --science, andMedicine

  3. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGerman --science,

  4. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGerman --science,Medicine --

  5. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGerman --science,Medicine

  6. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGerman

  7. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicine -- Energy,

  8. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicine --

  9. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicine --Medicine --

  10. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicine --Medicine

  11. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicine

  12. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicineMedicine --

  13. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicineMedicine

  14. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven SiteGermanMedicineMedicineMedicine

  15. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhaven

  16. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine -- Energy, science, and

  17. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine -- Energy, science,

  18. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine -- Energy,

  19. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine -- Energy,Medicine --

  20. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine -- Energy,Medicine

  1. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine -- Energy,MedicineMedicine

  2. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine --

  3. Browse by Discipline -- E-print Network Subject Pathways: Biology and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials FindAdvancedBrookhavenMedicine --Medicine -- Energy,

  4. nature structural & molecular biology VOLUME 19 NUMBER 6 JUNE 2012 633 a rt i c l e s

    E-Print Network [OSTI]

    Lim, Wendell

    biophysical characterization, the structural underpinnings of how voltage con- trols Ci-VSP function have of gating loop residue Glu411. Functional investigation of a battery of structure-based mutants evaluated

  5. A DISCIPLINED APPROACH TO ACCIDENT ANALYSIS DEVELOPMENT AND CONTROL SELECTION

    SciTech Connect (OSTI)

    Ortner, T; Mukesh Gupta, M

    2007-04-13T23:59:59.000Z

    The development and use of a Safety Input Review Committee (SIRC) process promotes consistent and disciplined Accident Analysis (AA) development to ensure that it accurately reflects facility design and operation; and that the credited controls are effective and implementable. Lessons learned from past efforts were reviewed and factored into the development of this new process. The implementation of the SIRC process has eliminated many of the problems previously encountered during Safety Basis (SB) document development. This process has been subsequently adopted for use by several Savannah River Site (SRS) facilities with similar results and expanded to support other analysis activities.

  6. Technical Report TR-014 May 2001 Research Section, Vancouver Forest Region, BCMOF Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife just like Forest Region, BCMOF Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology

  7. Cite this: Lab Chip, 2013, 13, 1457 Unconventional microfluidics: expanding the discipline

    E-Print Network [OSTI]

    Cite this: Lab Chip, 2013, 13, 1457 Unconventional microfluidics: expanding the discipline DOI: 10*a Since its inception, the discipline of microfluidics has been harnessed for innovations-effect of stereotyping microfluidics as a platform for medical diagnostics and miniaturized lab processes

  8. Protein Structure Analysis Iosif Vaisman

    E-Print Network [OSTI]

    Vaisman, Iosif

    Crystallography NMR Spectroscopy Protein Informatics Structural Bioinformatics Computational Structural Biology/ Proteins Alberts B, et al. Molecular Biology of the Cell. Proteins TTCCPSIVARSNFNVCRLPGTPEAICATYTGCIIIPGATCPGDYAN Hartl F.U. et al., Nature, 2011 Proteins Protein Science Biochemistry Biophysics Molecular Biology

  9. Protein Structure Analysis Iosif Vaisman

    E-Print Network [OSTI]

    Vaisman, Iosif

    Informatics Structural Bioinformatics Computational Structural Biology Protein Engineering Protein Design Drug/ Proteins Alberts B, et al. Molecular Biology of the Cell. Proteins TTCCPSIVARSNFNVCRLPGTPEAICATYTGCIIIPGATCPGDYAN Protein Science Biochemistry Biophysics Molecular Biology Crystallography NMR Spectroscopy Protein

  10. Protein Structure Analysis Iosif Vaisman

    E-Print Network [OSTI]

    Vaisman, Iosif

    Biology Crystallography NMR Spectroscopy Protein Informatics Structural Bioinformatics Computational Structural Biology Protein Engineering Protein Design Drug Design Molecular Modeling Proteomics Structural Weissig (Eds) Structural bioinformatics Hoboken, N.J. : Wiley-Liss, 2003. Jenny Gu, Philip Bourne (Eds

  11. Biological Safety

    Broader source: Energy.gov [DOE]

    The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

  12. Biological Evaluation of the Behavioral Guidance Structure at Lower Granite Dam on the Snake River, Washington in 1998

    SciTech Connect (OSTI)

    Adams, Noah (U.S. Geological Survey, Biological Resource Division); Johnson, Gary E. (BATTELLE (PACIFIC NW LAB)); Rondorf, Dennis W. (VISITORS); Anglea, Steven M. (BATTELLE (PACIFIC NW LAB)); Wik, Timothy O. (U.S. Army Corps of Engineers - Walla Walla District)

    2001-01-01T23:59:59.000Z

    In 1998 a behavioral guidance structure (BGS; a steel wall 330m long and 17-24 m deep) was installed in the forebay of Lower Granite Dam on the Snake River, Washington. The purpose of the BGS was to change the horizontal distribution of downstream migrants approaching the south half of the powerhouse by guiding them toward the surface bypass and collector attached to the dam upstream of the north half of the powerhouses. The effectiveness of the BGS was evaluated with biotelemetry and hydroacoustics. The BGS was designed to be movable, thereby allowing a comparison between the horizontal distribution of the fish when the BGS was deployed as a diversion device and when the BGS was moved 800 m upstream of the dam and no longer influenced fish movements immediately upstream of the powerhouse. Radio telemetry and hydroacoustic techniques showed that about 80% of the fish migrating toward Turbines 1-3 were successfully diverted north. Radio telemetry data revealed that the mean residence times of chinook salmon, hatchery steelhead, and wild steelhead were 1.6, 1.7, and 2.4 times longer, respectively, when the BGS was out compared to when it was in. And overall fish passage efficiency was significantly higher when the BGS was in (93.7%) than out (91.2%).

  13. Multi-discipline Waste Acceptance Process at the Nevada National Security Site - 13573

    SciTech Connect (OSTI)

    Carilli, Jhon T. [US Department Of Energy, Nevada Site Office, P. O. Box 98518, Las Vegas, Nevada 89193-8518 (United States)] [US Department Of Energy, Nevada Site Office, P. O. Box 98518, Las Vegas, Nevada 89193-8518 (United States); Krenzien, Susan K. [Navarro-Intera, LLC, P. O. Box 98952, Las Vegas, Nevada 89193-8952 (United States)] [Navarro-Intera, LLC, P. O. Box 98952, Las Vegas, Nevada 89193-8952 (United States)

    2013-07-01T23:59:59.000Z

    The Nevada National Security Site low-level radioactive waste disposal facility acceptance process requires multiple disciplines to ensure the protection of workers, the public, and the environment. These disciplines, which include waste acceptance, nuclear criticality, safety, permitting, operations, and performance assessment, combine into the overall waste acceptance process to assess low-level radioactive waste streams for disposal at the Area 5 Radioactive Waste Management Site. Four waste streams recently highlighted the integration of these disciplines: the Oak Ridge Radioisotope Thermoelectric Generators and Consolidated Edison Uranium Solidification Project material, West Valley Melter, and classified waste. (authors)

  14. Purdue extension Agricultural&Biological

    E-Print Network [OSTI]

    for an extended period and encourage biological treatment to minimize organic matter (BOD), nitrogenPurdue extension Don Jones Agricultural&Biological Engineering Alan Sutton AnimalSciences Purdue structures must be designed and managed to contain manure, wastewater, contaminated runoff, and ma- nure

  15. 2009 MICROBIAL POPULATION BIOLOGY GORDON RESEARCH CONFERENCES JULY 19-24,2009

    SciTech Connect (OSTI)

    ANTHONY DEAN

    2009-07-24T23:59:59.000Z

    The 2009 Gordon Conference on Microbial Population Biology will cover a diverse range of cutting edge issues in the microbial sciences and beyond. Firmly founded in evolutionary biology and with a strongly integrative approach, past Conferences have covered a range of topics from the dynamics and genetics of adaptation to the evolution of mutation rate, community ecology, evolutionary genomics, altruism, and epidemiology. The 2009 Conference is no exception, and will include sessions on the evolution of infectious diseases, social evolution, the evolution of symbioses, experimental evolution, adaptive landscapes, community dynamics, and the evolution of protein structure and function. While genomic approaches continue to make inroads, broadening our knowledge and encompassing new questions, the conference will also emphasize the use of experimental approaches to test hypotheses decisively. As in the past, this Conference provides young scientists and graduate students opportunities to present their work in poster format and exchange ideas with leading investigators from a broad spectrum of disciplines. This meeting is never dull: some of the most significant and contentious issues in biology have been thrashed out here. The 2009 meeting will be no exception.

  16. Technical Report TR-014 May 2001 Research Section, Vancouver Forest Region, BCMOF Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife TR-014 Tools9T 6E9, 250-751-7001 Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

  17. Systems Biology. | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology. Systems Biology. Abstract: The biology revolution over the last 50 years has been driven by the ascendancy of molecular biology. This was enthusiastically embraced by most...

  18. Electrical Engineering is a diverse discipline encompassing computer and information systems, controls, lasers,

    E-Print Network [OSTI]

    Rohs, Remo

    70 ELECTRICAL Electrical Engineering is a diverse discipline encompassing computer and information environmental engineering and manufacturing to semiconductors and telecommunications. The Electrical Engineering Technology and the Signal and Image Processing institute. PROGRAMS AVAILABLE Electrical Engineering

  19. Electrical Engineering (EE) is a diverse discipline encompassing computer and information systems, controls,

    E-Print Network [OSTI]

    Rohs, Remo

    70 ELECTRICAL Electrical Engineering (EE) is a diverse discipline encompassing computer, photonics, and quantum information processing. MAJORS & AREAS OF EMPHASIS ElectricalEngineering ComputerEngineering)Algorithmsandcomputationalmeth- odsforefficientsolutionofengineeringproblems. Introductiontoengineeringsoftwaretools. EE 200L Foundations of Electrical Engineer- ing Systems

  20. Why Should I Study Engineering? Georgia Southern offers three engineering disciplines Civil, Electrical and Mechanical.

    E-Print Network [OSTI]

    Hutcheon, James M.

    , Electrical and Mechanical. Engineers plan, design, develop, test and analyze infrastructure components (CivilWhy Should I Study Engineering? Georgia Southern offers three engineering disciplines Civil), electronic systems (Electrical), and systems with moving parts (Mechanical) that affect and improve people

  1. electrical engineering (EE) Electrical Engineering is a diverse discipline encompassing computer and

    E-Print Network [OSTI]

    Rohs, Remo

    62 electrical engineering (EE) Electrical Engineering is a diverse discipline encompassing computer environmental engineering and manufacturing to semiconductors and telecommunications. The Electrical Engineering. Programs Available Electrical Engineering Bachelor of Science 131 units Computer Engineering

  2. electrical (EE) Electrical Engineering is a diverse discipline encompassing computer and

    E-Print Network [OSTI]

    Rohs, Remo

    66 electrical (EE) Electrical Engineering is a diverse discipline encompassing computer environmental engineering and manufacturing to semiconductors and telecommunica- tions. The Electrical Technology and the Signal and Image Processing institute. Programs Available Electrical Engineering

  3. electrical engineering (EE) Electrical Engineering is a diverse discipline encompassing computer and

    E-Print Network [OSTI]

    Rohs, Remo

    62 electrical engineering (EE) Electrical Engineering is a diverse discipline encompassing computer environmental engineering and manufacturing to semiconductors and telecommunications. The Electrical Engineering Technology and the Signal and Image Process- ing institute. Programs Available Electrical Engineering

  4. To appear in Topics in Cognitive Science How Can Philosophy be a True Cognitive Science Discipline?

    E-Print Network [OSTI]

    Bechtel, William

    and cognitive neuroscience. Second, analyses of mental representation address both their vehicle in the autonomous disciplines. Indeed, for those discussions that do not afford linkage to the rest of cognitive

  5. The relationship of parental consistency in discipline to locus of control in preschoolers

    E-Print Network [OSTI]

    Schmidt, Corliss Theresa

    1979-01-01T23:59:59.000Z

    THE RELATIONSHIP OF PARENTAL CONSISTENCY IN DISCIPLINE TO LOCUS OF CONTROL IN PRESCHOOLERS A Thesis by CORLISS THERESA SCHMIDT Submitted to the Graduate College of Texas AIIM University in partial fulfillment of the requirement for the degree... of MASTER OF SCIEI'ICE August 1979 Major Subject: Psychology THE RELATIONSHIP OF PARENTAL CONSISTENCY IN DISCIPLINE TO LOCUS OF CONTROL IN PRESCHOOLERS A Thesis by CORLISS THERESA SCHMIDT Approved as to style and content by: ( a a of Committee...

  6. Loop Quantum Theory Applied to Biology and Nonlinear Whole Biology

    E-Print Network [OSTI]

    Yi-Fang Chang

    2008-01-02T23:59:59.000Z

    The loop quantum theory, which constitutes a very small discontinuous space, as new method is applied to biology. The model of protein folding and lungs is proposed. In the model, some known results are used, and four approximate conclusions are obtained: their structures are quantized, their space regions are finite, various singularities correspond to folding and crossed points, and different types of catastrophe exist. Further, based on the inseparability and correlativity of the biological systems, the nonlinear whole biology is proposed, and four basic hypotheses are formed. It may unify reductionism and holism, structuralism and functionalism. Finally, the medical meaning of the theory is discussed briefly.

  7. Technical Report TR-011 March 2000 Research Section, Vancouver Forest Region, BCMOF Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife TR-011 Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife #12;Technical ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife Page Summary

  8. Evaluating Service Disciplines for On-Demand Mobile Data Collection

    E-Print Network [OSTI]

    Cai, Lin

    the dense deployment of nodes and thus introduces extra costs. Another data collection approach utilizes mobile element example is the Seaeye Sabertooth [12], a battery-powered autonomous underwater vehicle the smart buoy equipped with Seatext from WFS [13], the structural health monitoring with radio

  9. S09 Symposium KK, Structure-Property Relationships in Biomineralized and Biomimetic Composites

    SciTech Connect (OSTI)

    David Kisailus; Lara Estroff; Himadri S. Gupta; William J. Landis; Pablo D. Zavattieri

    2010-06-07T23:59:59.000Z

    The technical presentations and discussions at this symposium disseminated and assessed current research and defined future directions in biomaterials research, with a focus on structure-function relationships in biological and biomimetic composites. The invited and contributed talks covered a diverse range of topics from fundamental biology, physics, chemistry, and materials science to potential applications in developing areas such as light-weight composites, multifunctional and smart materials, biomedical engineering, and nanoscaled sensors. The invited speakers were chosen to create a stimulating program with a mixture of established and junior faculty, industrial and academic researchers, and American and international experts in the field. This symposium served as an excellent introduction to the area for younger scientists (graduate students and post-doctoral researchers). Direct interactions between participants also helped to promote potential future collaborations involving multiple disciplines and institutions.

  10. Biological preconcentrator

    DOE Patents [OSTI]

    Manginell, Ronald P. (Albuquerque, NM); Bunker, Bruce C. (Albuquerque, NM); Huber, Dale L. (Albuquerque, NM)

    2008-09-09T23:59:59.000Z

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  11. S e p t e m b e r 1 9 9 7 Biological and

    E-Print Network [OSTI]

    of the New Era Atoms for Health 21 Slices of Life: Medical Imaging 23 High-Tech Treatments: Isotopes mandate to exploit the use of fissionable and radioactive material for medical purposes and, at the same advances at the interfaces between such disciplines as biology and information science. s From the early

  12. Development and origin of the microgranular structure in Latosols of the Brazilian Central Plateau: significance of texture, mineralogy, and biological activity

    E-Print Network [OSTI]

    Boyer, Edmond

    Plateau: significance of texture, mineralogy, and biological activity Adriana Reatto(1,2) , Ary Bruand(2 of the latter that was reported as being possibly related to the fine material mineralogy, location with different proportions but without any relationship with their texture and mineralogy. Actually, the types

  13. 6th Annual Systems Biology Symposium: Systems Biology and the Environment

    SciTech Connect (OSTI)

    Galitski, Timothy, P.

    2007-04-01T23:59:59.000Z

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology is an annual two-day event gathering the most influential researchers transforming biology into an integrative discipline investigating complex systems. In recognition of the fundamental similarity between the scientific problems addressed in environmental science and systems biology studies at the molecular, cellular, and organismal levels, the 2007 Symposium featured global leaders in Systems Biology and the Environment. The objective of the 2007 Systems Biology and the Environment International Symposium was to stimulate interdisciplinary thinking and research that spans systems biology and environmental science. This Symposium was well aligned with the DOEs Genomics:GTL program efforts to achieve scientific objectives for each of the three DOE missions: Develop biofuels as a major secure energy source for this century, Develop biological solutions for intractable environmental problems, and Understand biosystems climate impacts and assess sequestration strategies Our scientific program highlighted world-class research exemplifying these priorities. The Symposium featured 45 minute lectures from 12 researchers including: Penny/Sallie Chisholm of MIT gave the keynote address Tiny Cells, Global Impact: What Prochlorococcus Can Teach Us About Systems Biology, plus Jim Fredrickson of PNNL, Nitin Baliga of ISB, Steve Briggs of UCSD, David Cox of Perlegen Sciences, Antoine Danchin of Institut Pasteur, John Delaney of the U of Washington, John Groopman of Johns Hopkins, Ben Kerr of the U of Washington, Steve Koonin of BP, Elliott Meyerowitz of Caltech, and Ed Rubin of LBNL. The 2007 Symposium promoted DOEs three mission areas among scientists from multiple disciplines representing academia, non-profit research institutions, and the private sector. As in all previous Symposia, we had excellent attendance of participants representing 20-30 academic or research-oriented facilities along with 25-30 private corporations from 5-10 countries. To broaden the audience for the Symposium and ensure the continued accessibility of the presentations, we made the presentation videos available afterward on the ISBs website.

  14. EARTH SCIENCESEARTH SCIENCESEARTH SCIENCES This major includes a spectrum of disciplines focused on understanding the

    E-Print Network [OSTI]

    Krylov, Anna I.

    EARTH SCIENCESEARTH SCIENCESEARTH SCIENCES This major includes a spectrum of disciplines focused this understanding to read the record of earth history written in rocks and sediments, and on developing models by humans. Opportunities for Students Sigma Gamma Epsilon: The Omega Chapter of the national honorary earth

  15. 1.14 Note: Actual time to complete varies by discipline and departmental requirements. Dissertation Timeline

    E-Print Network [OSTI]

    Papalambros, Panos

    1.14 Note: Actual time to complete varies by discipline and departmental requirements. Dissertation Timeline STUDENT SERVICES: ACADEMIC RECORDS & DISSERTATIONS 915 E. Washington Street 0120 Rackham://wolverineaccess.umich.edu/ 6 months prior to Group Pre-Defense Review Rackham Format Guidelines http://www.rackham.umich.edu/downloads/oard-dissertation

  16. Electrical Engineering (EE) is a diverse discipline encompassing computer and information systems, controls,

    E-Print Network [OSTI]

    Rohs, Remo

    70 electrical Electrical Engineering (EE) is a diverse discipline encompassing computer information processing. ProgrAmS AVAilAble ElectricalEngineering Bachelor of Science 131 units ComputerEngineeringand Computer Science Bachelor of Science (see page 69) 132 units ElectricalEngineering(Computers) degree

  17. Electrical Engineering (EE) is a diverse discipline encompassing computer and information systems, controls,

    E-Print Network [OSTI]

    Rohs, Remo

    70 electrical Electrical Engineering (EE) is a diverse discipline encompassing computer information processing. mAjorS & AreAS of emPhASiS ElectricalEngineering ComputerEngineering& Computer Science (see page 69) ElectricalEngineering Emphasis in Computers See pages 76-77 for the curriculum

  18. Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Extension Note Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology.Understanding how the hydrologic cycle is affected by climate, trees and plants, soils, geology, topography, springs, or any Figure 1. The hydrologic cycle, or water cycle (courtesy of the US Geological Survey

  19. The NU Transportation Center Icarus Society presents.... "Airline Capacity Discipline: Where and

    E-Print Network [OSTI]

    Bustamante, Fabián E.

    The NU Transportation Center Icarus Society presents.... "Airline Capacity Discipline: Where and to What Extent? Aaron J. Gellman Professor of Transportation Northwestern University Transportation Center and Kellogg School of Management Thursday Nov. 29, 2012 3:00 pm Location: Transportation Center Chambers Hall

  20. Wind power is a rapidly growing and evolving field that crosses traditional academic disciplines and increasingly

    E-Print Network [OSTI]

    Delaware, University of

    ways in which society's understanding and acceptance of renewable energy power generation can impactWind power is a rapidly growing and evolving field that crosses traditional academic disciplines and increasingly requires practitioners who understand the relationships among the various components of wind

  1. Bioinformatics & Computational Biology

    E-Print Network [OSTI]

    Richner, Heinz

    Bioinformatics & Computational Biology Master of Science in Bioinformatics and Computational Biology (90 ECTS) Contact Information Programme administration Bioinformatics and Computational Biology.unifr.ch/msc Programme administration Bioinformatics and Computational Biology University of Bern Baltzerstrasse 6 CH

  2. Frontiers of NMR in Molecular Biology

    SciTech Connect (OSTI)

    NONE

    1999-08-25T23:59:59.000Z

    NMR spectroscopy is expanding the horizons of structural biology by determining the structures and describing the dynamics of blobular proteins in aqueous solution, as well as other classes of proteins including membrane proteins and the polypeptides that form the aggregates diagnostic of prion and amyloid diseases. Significant results are also emerging on DNA and RNA oligomers and their complexes with proteins. This meeting focused attention on key structural questions emanating from molecular biology and how NMR spectroscopy can be used to answer them.

  3. 32.02.02.V1.01 DISCIPLINE AND DISMISSAL Supplements System Policy 32.02 and System Regulation

    E-Print Network [OSTI]

    32.02.02.V1.01 DISCIPLINE AND DISMISSAL Supplements System Policy 32.02 and System Regulation 32) in the administration of the discipline and dismissal policy and regulation. 2.00 APPROVAL PROCEDURE 2.01 A supervisor that is available for review. Following the review, AgriLife Human Resources will, in keeping with System Regulation

  4. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    . Williams Professor of Biomedical Informations and Co-Director, Yale Computational Biology & Bioinformatics co-director of the Yale Computational Biology and Bioinformatics Program. In addition to the KeckBiological Statistics and Computational Biology Seminar Series Dr. Mark B. Gerstein Albert L

  5. The IceCube Data Acquisition Software: Lessons Learned during Distributed, Collaborative, Multi-Disciplined Software Development.

    SciTech Connect (OSTI)

    Beattie, Keith S; Beattie, Keith; Day Ph.D., Christopher; Glowacki, Dave; Hanson Ph.D., Kael; Jacobsen Ph.D., John; McParland, Charles; Patton Ph.D., Simon

    2007-09-21T23:59:59.000Z

    In this experiential paper we report on lessons learned during the development ofthe data acquisition software for the IceCube project - specifically, how to effectively address the unique challenges presented by a distributed, collaborative, multi-institutional, multi-disciplined project such as this. While development progress in software projects is often described solely in terms of technical issues, our experience indicates that non- and quasi-technical interactions play a substantial role in the effectiveness of large software development efforts. These include: selection and management of multiple software development methodologies, the effective useof various collaborative communication tools, project management structure and roles, and the impact and apparent importance of these elements when viewed through the differing perspectives of hardware, software, scientific and project office roles. Even in areas clearly technical in nature, success is still influenced by non-technical issues that can escape close attention. In particular we describe our experiences on software requirements specification, development methodologies and communication tools. We make observations on what tools and techniques have and have not been effective in this geographically disperse (including the South Pole) collaboration and offer suggestions on how similarly structured future projects may build upon our experiences.

  6. 1424 VOLUME 18 NUMBER 12 DECEMBER 2011 NATURE STRUCTURAL & MOLECULAR BIOLOGY B R I E F COM MU N I CAT I ON S

    E-Print Network [OSTI]

    Chandran, Kartik

    CAT I ON S A shared structural solution for neutralizing ebolaviruses João M Dias1,7, Ana I Kuehne2

  7. Disciplines Atmosphere

    E-Print Network [OSTI]

    Laurini, Robert

    Ultraviolet X-Rays Gamma-Rays Visible Red Orange Yellow Green Blue Violet 0,7 m 0,4 m Waves #12;Satellites of pollution (air, water, etc.) etc. #12;http://www.sbg.ac.at/geo/idrisi/gis_environmental_modeling/sf_papers/brendan_mackey/mackey_paper.html #12;Contents 1 Data acquisition 2 Environmental data modelling 3 Continuous data 4 XML

  8. Genomics-Bioinformatics Day: "Bioinformatics, Computational Biology, Systems Biology & Mathematical

    E-Print Network [OSTI]

    Goldschmidt, Christina

    3rd Genomics-Bioinformatics Day: "Bioinformatics, Computational Biology, Systems Biology on "Bioinformatics, Computational Biology, Systems Biology & Mathematical Biology: Their Relationship". Genomics, Bioinformatics, Computational Biology have a tremendous appeal and these fields have originated or grown

  9. Disease Ecology: Community Structure and Pathogen Dynamics [Review

    E-Print Network [OSTI]

    Peterson, A. Townsend

    2007-01-01T23:59:59.000Z

    BOOKS & MEDIA Disease Ecology: Community Structure and Pathogen Dynamics Sharon K. Collinge and Chris Ray, editors Oxford University Press, Cary, North Carolina, 2006 ISBN: 0198567073 Pages: 227; Price: US $124.50 The disciplines of community...

  10. Ninth International Workshop on Plant Membrane Biology

    SciTech Connect (OSTI)

    Not Available

    1993-12-31T23:59:59.000Z

    This report is a compilation of abstracts from papers which were discussed at a workshop on plant membrane biology. Topics include: plasma membrane ATP-ases; plant-environment interactions, membrane receptors; signal transduction; ion channel physiology; biophysics and molecular biology; vaculor H+ pumps; sugar carriers; membrane transport; and cellular structure and function.

  11. Technical Report TR-013 March 2001 Research Section, Vancouver Forest Region, BCMOF Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife TR-013 Hydrology March 2001 Roberts Creek Study Forest: Pre-harvest chemical characteristics of three S6 creeks-751-7001 Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

  12. Bioinformatics Computational Biology

    E-Print Network [OSTI]

    Mayfield, John

    Bioinformatics and Computational Biology Interdepartmental Graduate Program GRADUATE STUDENT HANDBOOK FALL 2006 Bioinformatics and Computational Biology Interdepartmental Graduate Program GRADUATE STUDENT HANDBOOK FALL 2006 #12;1 Welcome to the Bioinformatics and Computational Biology (BCB) program

  13. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    Science and the Center for Computational Biology and Bioinformatics at Columbia University. Dr. PeBiological Statistics and Computational Biology Seminar Series Dr. Itsik Pe'er Associate Professor of Computer Science Columbia University Itsik Pe'er is an associate professor in the Department of Computer

  14. Microfluidics for quantitative biology

    E-Print Network [OSTI]

    Adler, Micha

    2012-01-01T23:59:59.000Z

    CALIFORNIA, SAN DIEGO Microfluidics for Quantitative BiologyChapter 1: Microfluidics... 1 1.1OF THE DISSERTATION Microfluidics for Quantitative Biology

  15. Systems biology approach to bioremediation

    SciTech Connect (OSTI)

    Chakraborty, R.; Wu, C. H.; Hazen, T. C.

    2012-01-01T23:59:59.000Z

    Bioremediation has historically been approached as a ?black box? in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ?black box?.

  16. On Biology as an Emergent Science

    E-Print Network [OSTI]

    H. Pierre Noyes

    2007-05-31T23:59:59.000Z

    Biology is considered here as an "emergent science" in the sense of Anderson and of Laughlin and Pines. It is demonstrated that a straightforward mathematical definition of "biological system" is useful in showing how biology differs in structure from the lower levels in Anderson's "More is Different" hierarchy. Using cells in a chemostat as a paradigmatic exemplar of a biological system, it is found that a coherent collection of metabolic pathways through a single cell in the chemostat also satisfies the proposed definition of a biological system. This provides a theoretical and mathematical underpinning for Young's fundamental model of biological organization and integration. Evidence for the therapeutic efficacy of Young's method of analysis is provided by preliminary results of clinical trials of a specific application of Young's model to the treatment of cancer cachexia.

  17. November 2009 Peter Fratzl 1 MPG 2010+: BIOLOGICAL MATERIALS SCIENCES

    E-Print Network [OSTI]

    recognized that material properties can be critical for the biological function of molecules, tissuesNovember 2009 Peter Fratzl 1 MPG 2010+: BIOLOGICAL MATERIALS SCIENCES At a glance: A new field at the interface between biology and the materials sciences helps elucidating structure-function relations

  18. Science at the Edge Traditionally distinct scientific disciplines are merging to create new

    E-Print Network [OSTI]

    The Technology Barrier to Advanced Batteries for Energy Storage October 8 - Quantitative Biology/Gene Expression Energy Conversion November 5 - Quantitative Biology/Gene Expression in Development & Disease Seminar Gary, Departments of Chemistry and Materials Science, State University of New York at Binghamton Materials

  19. Plant Vascular Biology 2010

    SciTech Connect (OSTI)

    Ding, Biao

    2014-11-17T23:59:59.000Z

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  20. Report of The Structural Biology Subcommittee of The Biological and

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over OurTheBrookhavenMassachusetts RegionsPaul Bohn,Environmental Research Advisory

  1. Report of the Structural Biology Subcommittee of the Biological and

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over OurTheBrookhavenMassachusetts RegionsPaul Bohn,Environmental Research

  2. lstols@anl.gov Loyola University BS 1978 Biology

    E-Print Network [OSTI]

    Kemner, Ken

    Lucy Stols lstols@anl.gov . Education Loyola University BS 1978 Biology Chicago, IL Roosevelt determination. J Struc Funct Genomics 11, 31-39. Structural Genomics Consortium; China Structural Genomics

  3. Modeling Structural Properties of Breast Cancer Cells at NERSC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological cells Modeling structural properties of cells Goals To advance in detection, characterization, analysis and predictions of biological cells and their inherent...

  4. 2003 Synthetic Biology study

    E-Print Network [OSTI]

    Endy, Drew

    2007-08-14T23:59:59.000Z

    Biology is a technology for processing information, materials, and energy. As a technology platform, biological systems provide access to artifacts and processes across a range of scales (e.g., the ribosome is a programmable ...

  5. Mesangial cell biology

    SciTech Connect (OSTI)

    Abboud, Hanna E., E-mail: Abboud@uthscsa.edu

    2012-05-15T23:59:59.000Z

    Mesangial cells originate from the metanephric mesenchyme and maintain structural integrity of the glomerular microvascular bed and mesangial matrix homeostasis. In response to metabolic, immunologic or hemodynamic injury, these cells undergo apoptosis or acquire an activated phenotype and undergo hypertrophy, proliferation with excessive production of matrix proteins, growth factors, chemokines and cytokines. These soluble factors exert autocrine and paracrine effects on the cells or on other glomerular cells, respectively. MCs are primary targets of immune-mediated glomerular diseases such as IGA nephropathy or metabolic diseases such as diabetes. MCs may also respond to injury that primarily involves podocytes and endothelial cells or to structural and genetic abnormalities of the glomerular basement membrane. Signal transduction and oxidant stress pathways are activated in MCs and likely represent integrated input from multiple mediators. Such responses are convenient targets for therapeutic intervention. Studies in cultured MCs should be supplemented with in vivo studies as well as examination of freshly isolated cells from normal and diseases glomeruli. In addition to ex vivo morphologic studies in kidney cortex, cells should be studied in their natural environment, isolated glomeruli or even tissue slices. Identification of a specific marker of MCs should help genetic manipulation as well as selective therapeutic targeting of these cells. Identification of biological responses of MCs that are not mediated by the reninangiotensin system should help development of novel and effective therapeutic strategies to treat diseases characterized by MC pathology.

  6. Biological Systems Facilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    encompasses the areas of priority pathogen detection, extremophile biology and genomics, biohydrometallurgy, biomass conversion, coal bioprocessing, biodegradation...

  7. Molecular Mechanism of Biological Proton Transport

    SciTech Connect (OSTI)

    Pomes, R.

    1998-09-01T23:59:59.000Z

    Proton transport across lipid membranes is a fundamental aspect of biological energy transduction (metabolism). This function is mediated by a Grotthuss mechanism involving proton hopping along hydrogen-bonded networks embedded in membrane-spanning proteins. Using molecular simulations, the authors have explored the structural, dynamic, and thermodynamic properties giving rise to long-range proton translocation in hydrogen-bonded networks involving water molecules, or water wires, which are emerging as ubiquitous H{sup +}-transport devices in biological systems.

  8. Process Manual Biological & Agricultural

    E-Print Network [OSTI]

    Boas, Harold P.

    t t t t t t t . ~ t Process Manual Biological & Agricultural Engineering MANUAL FOR THE BIOLOGICAL AND AGRICULTURAL ENGINEERING DEPARTMENT TexasA&MUniversity Article I. NAME The name ofthis organization shall be the Biological and Agricultural Engineering Department (abbreviated

  9. Computational Biology & Bioinformatics

    E-Print Network [OSTI]

    Johnson, Marcia K.

    Computational Biology & Bioinformatics at Yale An Interdepartmental PhD Program and a Track within://www.yale.edu/graduateschool/admissions/apply_online.html 2 #12;Introduction Computational Biology and Bioinformatics (CBB) is a rapidly developing multi experimentation. Computational and theoretical approaches to understanding biological systems provide an essential

  10. Computational Biology & Bioinformatics

    E-Print Network [OSTI]

    Computational Biology & Bioinformatics at Yale An Interdepartmental PhD Program and a Track within://www.yale.edu/graduateschool/admissions/apply_online.html #12;3 Introduction Computational Biology and Bioinformatics (CBB) is a rapidly developing multi experimentation. Computational and theoretical approaches to understanding biological systems provide an essential

  11. Micro/nanofabricated environments for synthetic biology

    SciTech Connect (OSTI)

    Collier, Pat [ORNL; Simpson, Michael L [ORNL

    2011-01-01T23:59:59.000Z

    A better understanding of how confinement, crowding and reduced dimensionality modulate reactivity and reaction dynamics will aid in the rational and systematic discovery of functionality in complex biological systems. Artificial micro- and nanofabricated structures have helped elucidate the effects of nanoscale spatial confinement and segregation on biological behavior, particularly when integrated with microfluidics, through precise control in both space and time of diffusible signals and binding interactions. Examples of nanostructured interfaces for synthetic biology include the development of cell-like compartments for encapsulating biochemical reactions, nanostructured environments for fundamental studies of diffusion, molecular transport and biochemical reaction kinetics, and regulation of biomolecular interactions as functions of micro- and nanofabricated topological constraints.

  12. MINI-SYMPOSIUM COMPDYN2011 RELIABILITY OF STRUCTURAL AND MECHANICAL SYSTEMS

    E-Print Network [OSTI]

    Kreinovich, Vladik

    engineering disciplines such as earthquake, offshore, aeronautical, mechanical, and wind engineering in areas such as earthquake engineering, offshore engineering, fracture mechanics, aeronautical engineering, structural mechanics, and wind engineering are appropriate for this mini-symposium. #12;

  13. JOURNAL OF COMPUTATIONAL BIOLOGY Volume 11, Numbers 23, 2004

    E-Print Network [OSTI]

    Donald, Bruce Randall

    residues, 100% accuracy), matched to a variety of 3D structural models. Finally, we extend NVR to a second-throughput NMR structural biology can play an important role in structural genomics. We report an automated-protein 3D structural model. The algorithm requires only uniform 15 N-labeling of the protein and processes

  14. Animal Health Diagnostic Center Test and Fee Schedule Test Name Test Fee Discipline Test Days Lag** Samples Container Coolant Comments

    E-Print Network [OSTI]

    Keinan, Alon

    Animal Health Diagnostic Center Test and Fee Schedule Test Name Test Fee Discipline Test Days Lag** Samples Container Coolant Comments Equine Tests Equine Tests Acid Fast Stain (for bacteria) M-F 1-2 days 1 4 hours for equine. For more information, see Equine Cushing's Tests or AppendixC. For Equine only

  15. FUNDAMENTAL IMPACTS A Study of the Cross-Discipline and Societal Benefits of UK Research in Particle Physics

    E-Print Network [OSTI]

    Crowther, Paul

    a wide variety of other disciplines, particularly those in the medical and life sciences. Despite prodigious advances in our knowledge of fundamental physics, there remain many unanswered questions that will require significant technological innovation to address. This innovation will enable advances to be made

  16. UCF-3.0124 Discipline and Termination for Cause of Non-unit Faculty and A&P Staff Members.

    E-Print Network [OSTI]

    Van Stryland, Eric

    UCF-3.0124 Discipline and Termination for Cause of Non-unit Faculty and A&P Staff Members. (1) Just cause shall be defined as: (a) Incompetence; or (b) Misconduct. (2) Termination and Suspension. (a) The appointment of a non-unit faculty or an A&P staff member may be terminated or suspended during its term

  17. Chemistry & Biology Solvent Structure and Hammerhead

    E-Print Network [OSTI]

    Scott, William

    -ordered water molecule spanning N1 of G12 (the general base) and 20 -O of G8 (previously implicated in general resi- dues, G12 and G8, are positioned in the active site in a manner consistent with their previously hydrogen-bonding distance to the nucleophile 20 O of C17, and the ribose of G8 hydrogen bonds

  18. CSMB | Center for Structural Molecular Biology | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItem NotEnergy,ARMForms About Batteries BatteriesCAESMission Welcomefor GasforCSMB

  19. Towards Efficient Structural Analysis of Mathematical Expressions

    E-Print Network [OSTI]

    Yeung, Dit-Yan

    . Experiments done on some typical mathematical expressions show that our proposed methods can achieve speedup, structural analysis 1 Introduction Many documents in science and engineering disciplines contain mathematical expressions. The input of mathematical expressions into computers is often more difficult than the input

  20. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, J.M.; Palumbo, A.V.

    1998-09-15T23:59:59.000Z

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer. 2 figs.

  1. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, Janet M. (Ten Mile, TN); Palumbo, Anthony V. (Oak Ridge, TN)

    1998-01-01T23:59:59.000Z

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer.

  2. 3-D Printed Electrically and Optically Paced Skeletal Muscle Based Biological Machines Caroline Cvetkovic, Bioengineering

    E-Print Network [OSTI]

    Kilian, Kristopher A.

    3-D Printed Electrically and Optically Paced Skeletal Muscle Based Biological Machines Caroline Research Aims and Goals To use 3D printing technologies to fabricate the structure of the biological

  3. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2014-04-15T23:59:59.000Z

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  4. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

  5. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Focus Area team for Soil Metagenomics and Carbon Cycling develops and uses community genomics approaches to link the biological processes controlling belowground carbon storage...

  6. Breaking the Biological barriers to Cellulosic Ethanol: A Joint Research Agenda

    SciTech Connect (OSTI)

    Mansfield, Betty Kay [ORNL; Alton, Anita Jean [ORNL; Andrews, Shirley H [ORNL; Bownas, Jennifer Lynn [ORNL; Casey, Denise [ORNL; Martin, Sheryl A [ORNL; Mills, Marissa [ORNL; Nylander, Kim [ORNL; Wyrick, Judy M [ORNL

    2006-01-01T23:59:59.000Z

    A robust fusion of the agricultural, industrial biotechnology, and energy industries can create a new strategic national capability for energy independence and climate protection. In his State of the Union Address (Bush 2006), President George W. Bush outlined the Advanced Energy Initiative, which seeks to reduce our national dependence on imported oil by accelerating the development of domestic, renewable alternatives to gasoline and diesel fuels. The president has set a national goal of developing cleaner, cheaper, and more reliable alternative energy sources to substantially replace oil imports in the coming years. Fuels derived from cellulosic biomass - the fibrous, woody, and generally inedible portions of plant matter - offer one such alternative to conventional energy sources that can dramatically impact national economic growth, national energy security, and environmental goals. Cellulosic biomass is an attractive energy feedstock because it is an abundant, domestic, renewable source that can be converted to liquid transportation fuels. These fuels can be used readily by current-generation vehicles and distributed through the existing transportation-fuel infrastructure. The Biomass to Biofuels Workshop, held December 7-9, 2005, was convened by the Department of Energy's Office of Biological and Environmental Research in the Office of Science; and the Office of the Biomass Program in the Office of Energy Efficiency and Renewable Energy. The purpose was to define barriers and challenges to a rapid expansion of cellulosic-ethanol production and determine ways to speed solutions through concerted application of modern biology tools as part of a joint research agenda. Although the focus was ethanol, the science applies to additional fuels that include biodiesel and other bioproducts or coproducts having critical roles in any deployment scheme. The core barrier is cellulosic-biomass recalcitrance to processing to ethanol. Biomass is composed of nature's most ready energy source, sugars, but they are locked in a complex polymer composite exquisitely created to resist biological and chemical degradation. Key to energizing a new biofuel industry based on conversion of cellulose (and hemicelluloses) to ethanol is to understand plant cell-wall chemical and physical structures - how they are synthesized and can be deconstructed. With this knowledge, innovative energy crops - plants specifically designed for industrial processing to biofuel - can be developed concurrently with new biology-based treatment and conversion methods. Recent advances in science and technological capabilities, especially those from the nascent discipline of systems biology, promise to accelerate and enhance this development. Resulting technologies will create a fundamentally new process and biorefinery paradigm that will enable an efficient and economic industry for converting plant biomass to liquid fuels. These key barriers and suggested research strategies to address them are described in this report. As technologies mature for accomplishing this task, the technical strategy proceeds through three phases: In the research phase, within 5 years, an understanding of existing feedstocks must be gained to devise sustainable, effective, and economical methods for their harvest, deconstruction, and conversion to ethanol. Research is centered on enzymatic breakdown of cellulosic biomass to component 5- and 6-carbon sugars and lignin, using a combination of thermochemical and biological processes, followed by cofermentation of sugars to specified endproducts such as ethanol. Processes will be integrated and consolidated to reduce costs, improve efficacy, reduce generation of and sensitivity to inhibitors, and improve overall yields and viability in biorefinery environments. The technology deployment phase, within 10 years, will include creation of a new generation of energy crops with enhanced sustainability, yield, and composition, coupled with processes for simultaneous breakdown of biomass to sugars and cofermentation of sugars via new biological system

  7. Systems Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposed Action(InsertAbout the GeothermalSystems Biology

  8. Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science [AS or upper division) 4 #12;Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor Summary on page 2 Conservation Biology Concentration Elective 2 See note 3 on page 2 Semester Five: [15

  9. AGRICULTURAL AND BIOLOGICAL

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL AND BIOLOGICAL ENGINEERING UNDERGRADUATE PROGRAM Prepare... yourself for a career in integrating life and engineering for systems in agriculture, food, environment, and energy, and to contribute to the world's largest industry. COLLEGE OF ACES COLLEGE OF ENGINEERING #12;AGRICULTURAL AND BIOLOGICAL

  10. Human Embryology & Developmental Biology

    E-Print Network [OSTI]

    Levi, Ran

    Biology is the modern synthesis of biological and medical sciences that looks at how the tissues, and is at the forefront of recent advances in modern medicine. Current research has shown that many of the molecular Web Pages for names). The Head of School of Medical Sciences is always available for advice regarding

  11. Molecular Biology DEGREE PROGRAMME

    E-Print Network [OSTI]

    Levi, Ran

    to the course co-ordinator for that module (See University Catalogue of Courses or SMS World Wide Web Pages in molecular biology have a wide range of career options, including virtually all areas of biology, medicine with mastering statistics, graphics and word processing software packages. General Enquiries The Degree Programme

  12. BEE 3650. Properties of Biological Materials Spring Semester 2009

    E-Print Network [OSTI]

    Walter, M.Todd

    ", in setting up the team lab project experiment and the associated specialized materials testing associatedBEE 3650. Properties of Biological Materials Spring Semester 2009 J A Bartsch, PE, 05/22/2009 Credit: 3 hours Catalogue description: Mechanics and structural properties of biological materials

  13. BEE 365. Properties of Biological Materials Spring Semester 2007

    E-Print Network [OSTI]

    Walter, M.Todd

    ", in setting up the team lab project experiment and the associated specialized materials testing associatedBEE 365. Properties of Biological Materials Spring Semester 2007 J A Bartsch, PE, 06/28/2007 Credit: 3 hours Catalogue description: Mechanics and structural properties of biological materials

  14. Extracting information from biological networks

    E-Print Network [OSTI]

    Chindelevitch, Leonid Alexandrovich

    2010-01-01T23:59:59.000Z

    Systems biology, the study of biological systems in a holistic manner, has been catalyzed by a dramatic improvement in experimental techniques, coupled with a constantly increasing availability of biological data. The ...

  15. Master track Theoretical Biology & Bioinformatics

    E-Print Network [OSTI]

    Utrecht, Universiteit

    their master. Our two MSc courses "Computational Biology" and "Bioinformatics and Evolutionary GenomicsMaster track Theoretical Biology & Bioinformatics Modeling and bioinformatics is an important Biology & Bioinformatics provides courses introducing you to the basic concepts of modeling

  16. FAS4932: ALGAE BIOLOGY AND ECOLOGY Instructor: Professor Edward Phlips

    E-Print Network [OSTI]

    Watson, Craig A.

    FAS4932: ALGAE BIOLOGY AND ECOLOGY Instructor: Professor Edward Phlips Main Office: Program algae, including evolution, classification, structure, photosynthesis, growth, and reproduction. Emphasis on the ecological role of algae in different aquatic ecosystems (e.g. open ocean, estuaries, coral

  17. The physical, environmental, and evolutionary determinants of biological architecture

    E-Print Network [OSTI]

    Kempes, Christopher Andrew Poling

    2013-01-01T23:59:59.000Z

    The relationship between structure and function is a longstanding and central topic in biology, evolution, and ecology. The importance of morphology is clearly visible in the diverse forms taken by innumerable organisms ...

  18. Viewing biology in action | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    biology in action Released: June 11, 2014 DOE-funded pilot program will create mesoscale biological imaging platform James Evans EMSL received first-year funding of almost...

  19. Todd Newberry: Professor of Biology

    E-Print Network [OSTI]

    Newberry, Andrew Todd; Jarrell, Randall; Regional History Project, UCSC Library

    2006-01-01T23:59:59.000Z

    Professor of Biology: Early Retirement page 44 Jarrell: ToProfessor of Biology: Early Retirement page 45 Jarrell: ToWar 33 Voluntary Early Retirement Incentive Program (VERIP)

  20. proteinsSTRUCTURE O FUNCTION O BIOINFORMATICS CASP8 TARGET CLASSIFICATION

    E-Print Network [OSTI]

    Richardson, David

    and Computational Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain 2 Biochemistry Tress, Structural and Computational Biology Programme, Spanish National Cancer Research Centre (CNIO

  1. Biological Interactions and Dynamics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    proactive "EMSL 2.0-style" research paradigm. Because of the rapid pace of modern genomics and systems biology research, it is necessary to respond rapidly and flexibly to...

  2. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal...

  3. Mathematics and biology: The interface, challenges and opportunities

    SciTech Connect (OSTI)

    Levin, S.A. (ed.) (Cornell Univ., Ithaca, NY (United States))

    1992-06-01T23:59:59.000Z

    The interface between mathematics and biology has long been a rich area of research, with mutual benefit to each supporting discipline. Traditional areas of investigation, such as population genetics, ecology, neurobiology, and 3-D reconstructions, have flourished, despite a rather meager environment for the funding of such work. In the past twenty years, the kind and scope of such interactions between mathematicians and biologists have changed dramatically, reaching out to encompass areas of both biology and mathematics that previously had not benefited. At the same time, with the closer integration of theory and experiment, and the increased reliance on high-speed computation, the costs of such research grew, though not the opportunities for funding. The perception became reinforced, both within the research community and at funding agencies, that although these interactions were expanding, they were not doing so at the rate necessary to meet the opportunities and needs. A workshop was held in Washington, DC, between April 28 and May 3, 1990 which drew together a broadly based group of researchers to synthesize conclusions from a group of working papers and extended discussions. The result is the report presented here, which we hope will provide a guide and stimulus to research in mathematical and computational biology for at least the next decade. The report identifies a number of grand challenges, representing a broad consensus among the participants.

  4. Technical Report TR-012 March 2001 Research Section, Vancouver Forest Region, BCMOF Research Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife

    E-Print Network [OSTI]

    Disciplines: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife TR-012: Ecology ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife #12;Technical Report TR ~ Geology ~ Geomorphology ~ Hydrology ~ Pedology ~ Silviculture ~ Wildlife Page Summary 2 Keywords 2

  5. From the portfolio to the diagram : architectural discourse and the transformation of the discipline of architecture in America, 1918-1943

    E-Print Network [OSTI]

    Pae, Hy?ng-min.

    1993-01-01T23:59:59.000Z

    This dissertation is an historical inquiry into the concomitant transformations of architectural discourse and the discipline of architecture in America. It proceeds on the theoretical assumption that the documents produced ...

  6. Traditionally distinct scientific disciplines are merging to create new opportunities. Share the excitement and challenge through seminars and

    E-Print Network [OSTI]

    University Protein Engineering for Biosensors and Biofuel Cells March 5 - Interdisciplinary Physics Seminar & Technology, Univ. of Maryland Global Simplicity and Hidden Complexity in the Functions of Biological Machines

  7. Biomineralized structural materials with functional optical properties

    E-Print Network [OSTI]

    Li, Ling, Ph. D. Massachusetts Institute of Technology

    2014-01-01T23:59:59.000Z

    Many biological structural materials exhibit "mechanical property amplification" through their intricate hierarchical composite designs. In the past several decades, significant progress has been achieved in elucidating ...

  8. 7.91J / 7.36J / 20.490J Foundations of Computational and Systems Biology, Spring 2004

    E-Print Network [OSTI]

    Burge, Christopher

    Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems. The principles ...

  9. Oxygen as a site specific structural probe in neutron diffraction

    SciTech Connect (OSTI)

    Neuefeind, Joerg C [ORNL; Simonson, J Michael {Mike} [ORNL; Salmon, Phil [University of Bath; Zeidler, Anita [University of Bath; Fischer, Henry E [Institut Laue-Langevin (ILL); Rauch, Helmut [E141 Atominstitut der & #xD6; sterreichischen Universit& #xE4; ten,; Markland, Thomas [Columbia University; Lemmel, Hartmut [Technical University Vienna

    2011-01-01T23:59:59.000Z

    Oxygen is a ubiquitous element, playing an essential role in most scientific and technological disciplines, and is often incorporated within a structurally disordered material where examples include molten silicates in planetary science, glasses used for lasers and optical communication, and water in biological processes. Establishing the structure of a liquid or glassy oxide and thereby its relation to the functional properties of a material is not, however, a trivial task owing to the complexity associated with atomic disorder. Here we approach this challenge by measuring the bound coherent neutron scattering lengths of the oxygen isotopes with the sensitive technique of neutron interferometry. We find that there is a small but finite contrast of 0.204(6) fm between the scattering lengths of the isotope 18O and oxygen of natural isotopic abundance natO, contrary to tables of recommended values. This has enabled us to investigate the structure of both light and heavy water by exploiting, for the first time, the method of oxygen isotope substitution in neutron diffraction, thus circumventing many of the significant problems associated with more traditional methods in which hydrogen is substituted by deuterium. We find a difference of ~0.5% between the O-H and O-D intra-molecular bond distances which is much smaller than recent estimates based on diffraction data and is found to be in excellent agreement with path integral molecular dynamics simulations made with a flexible polarisable water model. Our results demonstrate the potential for using oxygen isotope substitution as a powerful and effective site specific probe in a plethora of materials, of pertinence as instrumentation at next generation neutron sources comes online

  10. Model membranes as a tool for biological studies and biosensor applications

    E-Print Network [OSTI]

    Armendariz, Kevin P.

    2013-12-31T23:59:59.000Z

    The biological membrane is a fundamental cellular structure which forms the natural selective barrier separating cells from their environment. Model membranes have long been employed to study these complicated structures in controlled environments...

  11. Fishery Biology Graduate Programs

    E-Print Network [OSTI]

    Fishery Biology Graduate Programs University of Alaska Fairbanks, Alaska 997750820 Program/degrees/index.html University of Arizona Tucson, Arizona 95721 Program: Fisheries Conservation and Management http://ag.arizona.edu/srnr/academicprograms/wildlifefisheries/gradstudiesFisheries.html Auburn University Auburn, Alabama 368490001 Programs: Aquaculture, Aquatic Ecology, Fishery Management

  12. BIOLOGICAL ANALYSIS Mass Spectrometry

    E-Print Network [OSTI]

    Greenaway, Alan

    Microscope) Analytical Equipment High Performance Liquid Chromatography Fast Protein Liquid Chromatography Gas Chromatography GC/MS Elemental Analyser Molecular Biology Equipment Biorad PCR Machine reactor for scale up studies In-line Particle sizers Rheometers Separation tanks Oscillating column (4m

  13. Chemistry and Chemical Biology

    E-Print Network [OSTI]

    Linhardt, Robert J.

    and interdisciplinary areas, including biochemical solar energy research, artificial photosynthesis and bio Biology at Rensselaer invites applications from students interested in pursuing a Ph.D. degree in an interdisciplinary environment with research opportunities in emerging fields, such as energy and the environment

  14. Biological and Environmental

    E-Print Network [OSTI]

    and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. After capitalize on recent technological and scientific advances. Several multidisciplinary projects of key,ecosystemmonitoringandrestoration,combiningcropresearchandmicrobial engineering to make biofuels a viable alternative to fossil fuels, and personalized medicine to improve health

  15. Biological and Environmental Research

    E-Print Network [OSTI]

    recalcitrance. Using an integrated approach to solving the challenge of producing biofuel from cellulosic materials, the center will not only provide the scientific basis for affordable and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. BESC researchers have

  16. CANCER BIOLOGY Infectioustumourcells

    E-Print Network [OSTI]

    Nowak, Martin A.

    CANCER BIOLOGY Infectioustumourcells David Dingli and Martin A. Nowak Cancer cells are generally infectious agents and be transmitted between individuals. The current view of cancer development is that normal cells are transformed into tumour cells by sequential mutations that activate cancer- promoting

  17. ECOLOGY LABORATORY BIOLOGY 341

    E-Print Network [OSTI]

    Vonessen, Nikolaus

    Page 1 ECOLOGY LABORATORY BIOLOGY 341 Fall Semester 2008 Bighorn Sheep Rams at Bison Range National ecological data; and 3) oral and written communication skills. Thus, these ecology labs, and statistical analyses appropriate for ecological data. A major goal of this class will be for you to gain

  18. Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science [AS Geology Elective 3-4 See note 2 on page 2 General Elective 4 #12;Roadmap: Environmental and Conservation Summary on page 2 Conservation Biology Concentration Elective 2 See note 3 on page 2 Semester Five: [15

  19. Guest Editors' Introduction: Synthetic Biology

    E-Print Network [OSTI]

    Densmore, Douglas

    + undergraduate participants from around the world. Synthetic Biology had a global market which gene- rated $233 Tufts University h SYNTHETIC BIOLOGY IS trending, as evidenced by the recent achievements in biofuels

  20. Experiment design for systems biology

    E-Print Network [OSTI]

    Apgar, Joshua Farley

    2009-01-01T23:59:59.000Z

    Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. ...

  1. Modular architecture in biological networks

    E-Print Network [OSTI]

    Ramachandran, Gopal (Gopal Sebastian)

    2007-01-01T23:59:59.000Z

    In the past decade, biology has been revolutionized by an explosion in the availability of data. Translating this new wealth of information into meaningful biological insights and clinical breakthroughs will require a ...

  2. Biological Engineering integrates life sciences

    E-Print Network [OSTI]

    Walter, M.Todd

    mitigating 40 million pounds of carbon dioxide greenhouse gases each year, and would pay for itself in les with the constantly evolving science of biology, the field of Biological Engineering tackles local, national

  3. STITCHER: Dynamic assembly of likely amyloid and prion beta-structures from secondary structure predictions

    E-Print Network [OSTI]

    Bryan, Allen W.

    The supersecondary structure of amyloids and prions, proteins of intense clinical and biological interest, are difficult to determine by standard experimental or computational means. In addition, significant conformational ...

  4. Biological Interactions and Dynamics Workshop | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Interactions and Dynamics Workshop Biological Interactions and Dynamics Workshop Wiley HS, Kaplan S. 2011. "Biological Interactions and Dynamics Science Theme Advisory...

  5. 2013 Biological Hydrogen Production Workshop Summary Report ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Hydrogen Production Workshop Summary Report 2013 Biological Hydrogen Production Workshop Summary Report November 2013 summary report for the 2013 Biological Hydrogen...

  6. Environmental Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    microbiology, biogeochemistry, molecular biology, molecular dynamics, bioinformatics, genomics, neutron science, chemistry, and computing-and spans multiple scales, from the...

  7. Systems Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of interdisciplinary scientists. Additional systems biology resources Research Highlights Media Mentions Publications Newsletters Biosciences Division Recent news releases 11...

  8. Probabilistic Approaches in Comparative Analysis of Biological Networks and Sequences

    E-Print Network [OSTI]

    Sahraeian, Sayed 1983-

    2013-01-07T23:59:59.000Z

    PROBABILISTIC APPROACHES IN COMPARATIVE ANALYSIS OF BIOLOGICAL NETWORKS AND SEQUENCES A Dissertation by SAYED MOHAMMAD EBRAHIM SAHRAEIAN Submitted to the O ce of Graduate Studies of Texas A&M University in partial ful llment...: Electrical Engineering Copyright 2013 Sayed Mohammad Ebrahim Sahraeian ABSTRACT Comparative analysis of genomic data investigates the relationship of genome structure and function across di erent biological species to shed light on their sim- ilarities...

  9. Single Molecule Probes of Lipid Membrane Structure

    E-Print Network [OSTI]

    Livanec, Philip W.

    2009-12-14T23:59:59.000Z

    Biological membranes are highly heterogeneous structures that are thought to use this heterogeneity to organize and modify the function of membrane constituents. Probing membrane organization, structure, and changes therein ...

  10. Perspectives Computational Biology in Brazil

    E-Print Network [OSTI]

    Neshich, Goran

    Perspectives Computational Biology in Brazil Goran Neshich Introduction At the request of the PLoS Computational Biology Editor-in- Chief, I agreed to write about computational biology in Brazil (see author of the field itself is short); b) the current state of the field in Brazil; c) the influence of computational

  11. COMPUTATIONAL MOLECULAR BIOLOGY TRAINING PROGRAM

    E-Print Network [OSTI]

    Mayfield, John

    in the burgeoning fields of bioinformatics and computational biology. A major outcome of the initial funding period was the establishment of ISU's interdepartmental graduate program in Bioinformatics and Computational Biology (BCB for Research Excellence in Bioinformatics and Computational Biology (BCB). The ISU-NMSU partnership

  12. Biological particle identification apparatus

    DOE Patents [OSTI]

    Salzman, Gary C. (Los Alamos, NM); Gregg, Charles T. (Los Alamos, NM); Grace, W. Kevin (Los Alamos, NM); Hiebert, Richard D. (Los Alamos, NM)

    1989-01-01T23:59:59.000Z

    An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

  13. 7.013 Introductory Biology, Spring 2005

    E-Print Network [OSTI]

    Sive, Hazel L.

    The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological ...

  14. Autofermentative Biological Hydrogen Production by Cyanobacteria...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Autofermentative Biological Hydrogen Production by Cyanobacteria Autofermentative Biological Hydrogen Production by Cyanobacteria Presentation by Charles Dismukes, Rutgers...

  15. Biology and Medicine Division annual report, 1987

    SciTech Connect (OSTI)

    Not Available

    1988-04-01T23:59:59.000Z

    Modern biology is characterized by rapid change. The development of new tools and the results derived from their application to various biological systems require significant shifts in our concepts and the strategies that are adopted to analyze and elucidate mechanisms. In parallel with exciting new scientific developments our organizational structure and programmatic emphases have altered. These changes and developments have enabled the life sciences at LBL to be better positioned to create and respond to new opportunities. The work summarized in this annual report reflects a vital multifaceted research program that is in the vanguard of the areas represented. We are committed to justifying the confidence expressed by LBL through the new mission statement and reorganizational changes designed to give greater prominence to the life sciences.

  16. The Bioinformatics & Systems Biology group (http://bioinformatics.psb.ugent.be/) at the VIB Department of Plant

    E-Print Network [OSTI]

    Gent, Universiteit

    The Bioinformatics & Systems Biology group (http://bioinformatics.psb.ugent.be/) at the VIB Administrator/Bioinformatician As a member of VIB's a new bioinformatics project framed in the computational Department of Plant Systems Biology studies the structure, function and evolution of biological networks

  17. DOE Chair of Excellence in Environmental Disciplines-Final Technical Report

    SciTech Connect (OSTI)

    Kurunganty, Sastry; Lorn, Roberto; Roque-Malherbe, Rolando; Hijazi, Yazan; Nieto, Santander; Gmez, Will A.; Ducong, Jos; Cotto, Mara del C.; Muiz, Carlos; Daz, Francisco J.; Neira, Carlos F.; Mrquez, Francisco; Del Valle, W.; Thommes, M.

    2014-02-19T23:59:59.000Z

    The report Massie Chair of Excellence Program at Universidad del Turabo, contract DE-FG02-95EW12610, during the period of 9/29/1995 to 9/29/2011. The initial program aims included development of academic programs in the Environmental Sciences and Engineering, and Research and Development focused initially on environmentally friendly processes and later revised also include: renewable energy and international cooperation. From 1995 -2005, the Program at UT lead the establishment of the new undergraduate program in electrical engineering at the School of Engineering (SoE), worked on requirements to achieve ABET accreditation of the SoE B.S. Mechanical Engineering and B.S. Electrical Engineering programs, mentored junior faculty, taught undergraduate courses in electrical engineering, and revised the electrical engineering curriculum. Engineering undergraduate laboratories were designed and developed. The following research sub-project was developed: Research and development of new perovskite-alumina hydrogen permeable asymmetrical nanostructured membranes for hydrogen purification, and extremely high specific surface area silica materials for hydrogen storage in the form of ammonia, Dr. Rolando Roque-Malherbe Subproject PI, Dr. Santander Nieto and Mr. Will Gmez Research Assistants. In 2006, the Massie Chair of Excellence Program was transferred to the National Nuclear Security Agency, NNSA and DNN. DoE required a revised proposal aligned with the priorities of the Administration. The revised approved program aims included: (1) Research (2) Student Development: promote the development of minority undergraduate and graduate students through research teams, internships, conferences, new courses; and, (3) Support: (a) Research administration and (b) Dissemination through international conferences, the UT Distinguished Lecturer Series in STEM fields and at the annual Universidad del Turabo (UT) Researchers Conference. Research included: Sub-Project 1: Synthesis and Characterization of low Refractive Index Aerogel Silica for Cherenkov Counters- Dr. Rolando Roque-Malherbe Sub-project PI, Dr. Jose Duconge Sub-project Co-PI, Dr. Santander Nieto Assistant Researcher, Francisco Diaz and Carlos Neira Associate Researchers. The initial aim of this sub-project was changed to the synthesis and characterization of extremely high specific surface area aerogel silica for gas storage. A high specific surface area silica gel that has applications in gas drying, cleaning operation useful in nuclear industry in process was developed. Sub-Project 2: Investigation Study of Magnetic and Electronic Transport Properties at Material Interfaces in Magnetic Multilayer Heterostructure using Gd. Dr. Yazan Hijazi, Sub-project Co-PI. UT developed the capability and infrastructure to produce high quality thin-film magnetic films and magnetic multilayer structures with fine control over film quality and thickness using sputter deposition capability to perform in-house electric and magnetic characterization of these films. The research experimentally quantified the effect of Gd incorporation within the magnetic multilayer structure and produce magnetic media with exchanged decoupled multilevel magnetic anisotropy. From September 2006 to September 2011 the Massie Chair produced nineteen (19) publications, (including 3 books), five (5) presentations and three (3) international conferences abstracts. A total of fourteen (14) undergraduates and (6) graduate students acquired research experience. Two Ph.D. students presented their dissertations on topics related to nuclear energy and graduated as follows: Mara Cotto (May 2009) and Eric Caldern (May 2011). Five of the participating undergraduate students graduated: Ramon Polanco (BSME, May 2009), Jason Prez (BSEE, May 2008), Rafael Coln (BSME, May 2008), Jessenia Marfisi (BS Chemistry, May 2008). Eleven (11) students were sent to National Laboratories (LANL, SNL and LLNL), NNSA and DoE facilities for summer internships. Twenty eight (28) undergraduate students participated in Summer Internships (2010,

  18. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiological and

  19. Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiologicalLaboratories

  20. Radiation physics, biophysics, and radiation biology

    SciTech Connect (OSTI)

    Hall, E.J.; Zaider, M.

    1993-05-01T23:59:59.000Z

    Research at the Center for Radiological Research is a multidisciplenary blend of physics, chemistry and biology aimed at understanding the mechanisms involved in the health problems resulting from human exposure to ionizing radiations. The focus is increased on biochemistry and the application of the techniques of molecular biology to the problems of radiation biology. Research highlights of the program from the past year are described. A mathematical model describing the production of single-strand and double-strand breaks in DNA as a function radiation quality has been completed. For the first time Monte Carlo techniques have been used to obtain directly the spatial distribution of DNA moieties altered by radiation. This information was obtained by including the transport codes a realistic description of the electronic structure of DNA. We have investigated structure activity relationships for the potential oncogenicity of a new generation of bioreductive drugs that function as hypoxic cytotoxins. Experimental and theoretical investigation of the inverse dose rate effect, whereby medium LET radiations actually produce an c effect when the dose is protracted, is now at a point where the basic mechanisms are reasonably understood and the complex interplay between dose, dose rate and radiation quality which is necessary for the effect to be present can now be predicted at least in vitro. In terms of early radiobiological damage, a quantitative link has been established between basic energy deposition and locally multiply damaged sites, the radiochemical precursor of DNA double strand breaks; specifically, the spatial and energy deposition requirements necessary to form LMDs have been evaluated. For the first time, a mechanically understood biological fingerprint'' of high-LET radiation has been established. Specifically measurement of the ratio of inter-to intra-chromosomal aberrations produces a unique signature from alpha-particles or neutrons.

  1. 2010 Tetrapyrroles, Chemistry & Biology of Gordon Research Conference

    SciTech Connect (OSTI)

    Angela Wilks

    2010-07-30T23:59:59.000Z

    The objective of the Chemistry & Biology of Tetrapyrroles Gordon Conference is to bring together researchers from diverse disciplines that otherwise would not interact. By bringing biologists, chemists, engineers and clinicians with a common interest in tetrapyrroles the conference provides a forum for cross-disciplinary ideas and collaboration. The perspective provided by biologists, chemists, and clinicians working in fields such as newly discovered defects in human porphyrin metabolism, the myriad of strategies for light harvesting in photosynthetic organisms, novel tetrapyrroles that serve as auxiliary chromophores or enzyme cofactors, synthetic strategies in the design of novel tetrapyrrole scaffolds, and tetrapyrrole based cell signaling and regulatory systems, makes this conference unique in the field. Over the years the growing evidence for the role of tetrapyrroles and their reactive intermediates in cell signaling and regulation has been of increasing importance at this conference. The 2010 conference on Chemistry & Biology of Tetrapyrroles will focus on many of these new frontiers as outlined in the preliminary program listed. Speakers will emphasize unpublished results and new findings in the field. The oral sessions will be followed by the highly interactive afternoon poster sessions. The poster sessions provide all conferees with the opportunity to present their latest research and to exchange ideas in a more informal setting. As in the past, this opportunity will continue during the nightly social gathering that takes place in the poster hall following the evening lectures. All conferees are encouraged to submit and present posters. At the conference the best poster in the areas of biology, chemistry and medicine will be selected by a panel of previous conference chairs.

  2. SECTION SEVEN DEFINITION OF TERMS Additional Subject Group of related modules within an academic discipline which is taken in addition to

    E-Print Network [OSTI]

    Davies, Christopher

    SECTION SEVEN DEFINITION OF TERMS Additional Subject Group of related modules within an academic(s). Single / Double / Triple module Unit of study with a value of 10/20/30 credits. Subject Group of related modules within one academic discipline. Timetable Group Groups within which a module's teaching and other

  3. SINGLE MOLECULE APPROACHES TO BIOLOGY, 2010 GORDON RESEARCH CONFERENCE, JUNE 27-JULY 2, 2010, ITALY

    SciTech Connect (OSTI)

    Professor William Moerner

    2010-07-09T23:59:59.000Z

    The 2010 Gordon Conference on Single-Molecule Approaches to Biology focuses on cutting-edge research in single-molecule science. Tremendous technical developments have made it possible to detect, identify, track, and manipulate single biomolecules in an ambient environment or even in a live cell. Single-molecule approaches have changed the way many biological problems are addressed, and new knowledge derived from these approaches continues to emerge. The ability of single-molecule approaches to avoid ensemble averaging and to capture transient intermediates and heterogeneous behavior renders them particularly powerful in elucidating mechanisms of biomolecular machines: what they do, how they work individually, how they work together, and finally, how they work inside live cells. The burgeoning use of single-molecule methods to elucidate biological problems is a highly multidisciplinary pursuit, involving both force- and fluorescence-based methods, the most up-to-date advances in microscopy, innovative biological and chemical approaches, and nanotechnology tools. This conference seeks to bring together top experts in molecular and cell biology with innovators in the measurement and manipulation of single molecules, and will provide opportunities for junior scientists and graduate students to present their work in poster format and to exchange ideas with leaders in the field. A number of excellent poster presenters will be selected for short oral talks. Topics as diverse as single-molecule sequencing, DNA/RNA/protein interactions, folding machines, cellular biophysics, synthetic biology and bioengineering, force spectroscopy, new method developments, superresolution imaging in cells, and novel probes for single-molecule imaging will be on the program. Additionally, the collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings in the beauty of the Il Ciocco site in Tuscany, provides an avenue for scientists from different disciplines to interact and brainstorm and promotes cross-disciplinary collaborations directed toward compelling biological problems.

  4. Mitotic chromosome structure

    SciTech Connect (OSTI)

    Heermann, Dieter W., E-mail: heermann@tphys.uni-heidelberg.de

    2012-07-15T23:59:59.000Z

    Mounting evidence is compiling linking the physical organizational structure of chromosomes and the nuclear structure to biological function. At the base of the physical organizational structure of both is the concept of loop formation. This implies that physical proximity within chromosomes is provided for otherwise distal genomic regions and thus hierarchically organizing the chromosomes. Together with entropy many experimental observations can be explained with these two concepts. Among the observations that can be explained are the measured physical extent of the chromosomes, their shape, mechanical behavior, the segregation into territories (chromosomal and territories within chromosomes), the results from chromosome conformation capture experiments, as well as linking gene expression to structural organization.

  5. Department of Systems Biology & Bioinformatics

    E-Print Network [OSTI]

    Rostock, Universitt

    Department of Systems Biology & Bioinformatics Faculty of Computer Sciences & Electrical, comparability and fairness. Practical Aspects and Soft Skills Technical Achievement Background understanding

  6. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    Welcome to the Administrative section of the Biological and Environmental Research Abstracts Database. Please logon. Logon Name: Password: Logon CommentsEmail Us * Security...

  7. CollegeofScience Biological Sciences

    E-Print Network [OSTI]

    Hickman, Mark

    ,populations,and even ecosystems. Our courses will help prepare you for a career in biology,be it in biodiversity

  8. COMPLEX BIOLOGICAL MECHANISMS: CYCLIC, OSCILLATORY,

    E-Print Network [OSTI]

    Bechtel, William

    COMPLEX BIOLOGICAL MECHANISMS: CYCLIC, OSCILLATORY, AND AUTONOMOUS William Bechtel and Adele- nomological framework and its focus on laws as the primary explanatory vehicle; for them, a scientific

  9. University of Southern California Computer science is an enabling discipline at the intersection of a wide array

    E-Print Network [OSTI]

    Zhou, Chongwu

    of a wide array of human endeavors, including biology, nanotechnology, robotics, education, the social Professors and 1 Distinguished Professor Almost every eligible assistant professor has won an NSF CAREERKempe, assistant professor of computer science, won the USC Viterbi School's Junior Research Award. In his research

  10. Staunton State Park Biological Inventory

    E-Print Network [OSTI]

    Staunton State Park Biological Inventory Prepared by: Susan Spackman, David Anderson, Jeremy Biological Inventory Prepared by: Susan Spackman, David Anderson, Jeremy Siemers, Phyllis Pineda, and Jill. The information management staff with CNHP was responsible for integrating the data resulting from the inventory

  11. FISHERY RESEARCH BIOLOGICAL LABORATORY, GALVESTON

    E-Print Network [OSTI]

    stations conduct fish ry re - search in the Gulf of Mexico as part of the work of the Bureau's Gulf, St. Pet rsburg Beach, Fla. Biological Res earch Biological Laboratory, Beaufort, N. C hw Gulf of Mexico Abundance of postlarval and juv nil shrimp Pink shrimp life history . Brown

  12. alkaline solution structure: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cells Benedek, George B. 228 HOUSEHOLD AND STRUCTURAL INSECTS Laboratory Evaluation of Boric Acid-Sugar Solutions as Baits Biology and Medicine Websites Summary: for Management...

  13. Complex biological and bio-inspired systems

    SciTech Connect (OSTI)

    Ecke, Robert E [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    The understanding and characterization ofthe fundamental processes of the function of biological systems underpins many of the important challenges facing American society, from the pathology of infectious disease and the efficacy ofvaccines, to the development of materials that mimic biological functionality and deliver exceptional and novel structural and dynamic properties. These problems are fundamentally complex, involving many interacting components and poorly understood bio-chemical kinetics. We use the basic science of statistical physics, kinetic theory, cellular bio-chemistry, soft-matter physics, and information science to develop cell level models and explore the use ofbiomimetic materials. This project seeks to determine how cell level processes, such as response to mechanical stresses, chemical constituents and related gradients, and other cell signaling mechanisms, integrate and combine to create a functioning organism. The research focuses on the basic physical processes that take place at different levels ofthe biological organism: the basic role of molecular and chemical interactions are investigated, the dynamics of the DNA-molecule and its phylogenetic role are examined and the regulatory networks of complex biochemical processes are modeled. These efforts may lead to early warning algorithms ofpathogen outbreaks, new bio-sensors to detect hazards from pathomic viruses to chemical contaminants. Other potential applications include the development of efficient bio-fuel alternative-energy processes and the exploration ofnovel materials for energy usages. Finally, we use the notion of 'coarse-graining,' which is a method for averaging over less important degrees of freedom to develop computational models to predict cell function and systems-level response to disease, chemical stress, or biological pathomic agents. This project supports Energy Security, Threat Reduction, and the missions of the DOE Office of Science through its efforts to accurately model biological systems at the molecular and cellular level. The project's impact encompasses applications to biofuels, to novel sensors and to materials with broad use for energy or threat reduction. The broad, interdisciplinary approach of CNLS offers the unparalleled strength of combining science backgrounds and expertise -a unique and important asset in attacking the complex science of biological organisms. This approach also allows crossfertilization, with concepts and techniques transferring across field boundaries.

  14. Biomimetic Mineralization: Mesoporous Biological mineral synthesis, in contrast to conven-

    E-Print Network [OSTI]

    Biomimetic Mineralization: Mesoporous Structures Biological mineral synthesis, in contrast of mineral crystals. Mesophases are materials which have domain length scales of the order of a few as a molecular blueprint for the site- directed formation of the inorganic phase, by providing an interface

  15. Computer Science Department Technion, IIT Algorithms in Computational Biology 236522

    E-Print Network [OSTI]

    Beimel, Amos

    Computer Science Department Technion, IIT Algorithms in Computational Biology 236522 Moed A Exam Spring 2007, 24.9.07 Lecturer: Shlomo Moran TA: Ilan Gronau - Exam Duraion: 3 hours - The Exam has 3 structure can be used to answer the desired queries. 2. (23 pts) Denote by Si the sequence S after deletion

  16. R E V I E W Effects of biological invasions on forest carbon

    E-Print Network [OSTI]

    Berkowitz, Alan R.

    R E V I E W Effects of biological invasions on forest carbon sequestration D . A . P E LT Z E R on the effects of some of the major drivers of global change on carbon (C) sequestration, particularly carbon that drive C sequestration. Keywords: biological invasion, carbon sequestration, community structure, forest

  17. Collection Policy: BIOCHEMISTRY, MOLECULAR AND CELL BIOLOGY Subject Scope | Priority Tables | Other policies . . .

    E-Print Network [OSTI]

    Angenent, Lars T.

    , recombinant DNA and its applications, metabolism, molecular biology, computer graphics in molecular biology regulation and chromatin structure in eukaryotes q Regulation of the heat shock genes q Control of gene-response regulatory protein in bacteria q Bacterial transcription mechanisms, especially termination, and control

  18. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology Visualisation of Large Amounts of Data Dave Ussery 27 February, 2008 #12;Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology #12;Comparative Microbial Genomics group

  19. Introduction to Bioinformatics A Systems Biology Approach

    E-Print Network [OSTI]

    Rocha, Luis

    Introduction to Bioinformatics A Systems Biology Approach Luis M. Rocha Complex Systems Modeling Computational Biology to Bioinformatics Course Layout: March 11-15, 2002 #12;P Systems Biology P Synthetic, Multi- Disciplinary Approach

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    E-Print Network [OSTI]

    Kelly, John J.

    DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida (Photo Credit: Michael Masellis, Biology Major Hurricane Savitz Hits Florida Future Science Teachers' Club Recent Grant Successes Forthcoming Publications

  1. The sequestration efficiency of the biological pump

    E-Print Network [OSTI]

    DeVries, Tim; Primeau, Francois; Deutsch, Curtis

    2012-01-01T23:59:59.000Z

    Preformed phosphate, soft tissue pump and atmospheric CO 2 ,efficiency of the biological pump Tim DeVries, 1 Francoisproduces a biological pump that reduces the concentration

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    E-Print Network [OSTI]

    Shoichet, Brian

    2011-01-01T23:59:59.000Z

    Biology and High Performance Computing Manfred Zorn, TeresaBiology and High Performance Computing Presenters: Manfred99-Portland High performance computing has become one of the

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    Broader source: Energy.gov [DOE]

    Breakout Session 2: Frontiers and Horizons Session 2-A: Synthetic Biology and the Promise of Biofuels Jonathan Burbaum, Program Director, Department of Energy, Office of Science, ARPAE

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    photosynthetic efficiency Improve chemical agronomic and agro-ecological control measures Modelling through translation of chemical biology tools and technologies Control weeds, disease and pests Minimise a platform to steer future research and policy directions. Encourage external outreach to engage

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    E-Print Network [OSTI]

    Walter, M.Todd

    Environmental Engineering Game Design Industrial Systems & Information Technology Information Science MaterialsPreparing for Transfer Majors: Biological Engineering Chemical Engineering Civil Engineering Computer Science Electrical & Computer Engineering Engineering Physics Environmental Engineering

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    Fang-Yen, Christopher

    research protocols involving hazardous materials, reviews construction design for safety features with or near biologically hazardous materials (infectious agents, biohazards or recombinant DNA). 1.3 "Infectious waste" or "biohazardous waste" is defined by the Pennsylvania Department of Environmental

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    E-Print Network [OSTI]

    Heller, Barbara

    1 Chemistry Division Department of Biological and Chemical Sciences, Illinois Institute-13 Chemistry Division invites nominations for Kilpatrick Fellowship for the academic year 2012's Chemistry Department from 19471960. Mary Kilpatrick was a chemistry faculty member from 1947

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    E-Print Network [OSTI]

    Norville, Julie Erin, 1980-

    2012-01-01T23:59:59.000Z

    The focus of my research is the development of technology for building compound biological systems from simpler pieces. I designed BioScaffold parts, a family of variable regions that can be inserted into a DNA sequence ...

  9. Biology Division progress report, October 1, 1993--September 30, 1995

    SciTech Connect (OSTI)

    NONE

    1995-10-01T23:59:59.000Z

    This Progress Report summarizes the research endeavors of the Biology Division of the Oak Ridge National Laboratory during the period October 1, 1993, through September 30, 1995. The report is structured to provide descriptions of current activities and accomplishments in each of the Division`s major organizational units. Lists of information to convey the entire scope of the Division`s activities are compiled at the end of the report. Attention is focused on the following research activities: molecular, cellular, and cancer biology; mammalian genetics and development; genome mapping program; and educational activities.

  10. Biological Science | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeIdleBiological Science Biological Science The protozoan

  11. 2013 METALS IN BIOLOGY GORDON RESEARCH CONFERENCE, JANUARY 20-25, 2013

    SciTech Connect (OSTI)

    Rosenzweig, Amy

    2013-01-25T23:59:59.000Z

    Typical topics for lectures and posters include: biochemical and biophysical characterization of new metal containing proteins, enzymes, nucleic acids, factors, and chelators from all forms of life; synthesis, detailed characterization, and reaction chemistry of biomimetic compounds; novel crystal and solution structures of biological molecules and synthetic metal-chelates; discussions of the roles that metals play in medicine, maintenance of the environment, and biogeochemical processes; metal homeostasis; application of theory and computations to the structure and mechanism of metal-containing biological systems; and novel applications of spectroscopy to metals in biological systems.

  12. Structure and function of Pseudomonas aeruginosa protein PA1324 (21170)

    E-Print Network [OSTI]

    Powers, Robert

    Northwest National Laboratory, Biological Sciences Division, Northeast Structural Genomics Consortium and Northeast Structural Genomics Consortium, Miami University, Oxford, Ohio 45056 Received 12 June 2008 aeruginosa PA1324; NMR; functional genomics; NMR high-throughput screens; protein-ligand binding; protein

  13. Structural Complexity of a Composite Amyloid Fibril

    E-Print Network [OSTI]

    Lewandowski, Jozef R.

    The molecular structure of amyloid fibrils and the mechanism of their formation are of substantial medical and biological importance, but present an ongoing experimental and computational challenge. An early high-resolution ...

  14. Integrative Biology Keith A. Crandall, Chair

    E-Print Network [OSTI]

    Hart, Gus

    . The bioinformatics major is for students with interests in both the computer and the biological sciences. The degree merges these interests in the areas of bioinformatics and computational biology, giving students Programs and Degrees BS Bioinformatics BS Biology Composite Teaching BS Integrative Biology Students should

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    E-Print Network [OSTI]

    Annamma, Subini; Morrison, Deb; Jackson, Darrell

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    the school to prison pipeline. Journal of Law and EducationThe school-to-prison-pipeline: Structuring legal reform. New2005). School to prison pipeline. Retrieved from http://

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    Kowalczykowski, Stephen C.

    .nature.com/nsmb/journal/vaop/ncurrent/fig_tab/nsmb.2775_SF6.html Supplementary Figure 6: Uncropped gels from Figure 4. From Structural and mechanistic.nature.com/nsmb/journal/vaop/ncurrent/fig_tab/nsmb.2775_SF6.html a) Uncropped gels corresponding to fig 4a .Yeast Top3 relaxation assay using pUC19 DNA

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    E-Print Network [OSTI]

    Engineering) Mechanical Engineering Mining, Metallurgy, and Materials Science (may include Metallurgical) Environmental Sciences (may include Agriculture, Ecology, Forestry, and Toxicology) General Biological

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    E-Print Network [OSTI]

    Chemical and Biological Engineering Department Code 1 CODE of the Department of Chemical of Chemical & Biological Engineering. For clarity of presentation, some passages are copied directly from shall offer an undergraduate chemical and biological engineering program of technological, scientific

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    E-Print Network [OSTI]

    Lu, Jiaheng

    A bioinformatics/computational biology postdoctoral research position available to analyze biological networks in plants A bioinformatics postdoctoral position is available immediately in the laboratory of Dr. Sue Rhee at the Carnegie Institution, Department of Plant Biology (Stanford, CA

  20. Cloning and characterization of EXC-1, an IRGP homologue that controls Intracellular Trafficking and the Maintenance of Shape in Small Biological Tubes

    E-Print Network [OSTI]

    Grussendorf, Kelly Ann

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    Biological tubes are ubiquitous structures that carry out vital roles. The formation and maintenance of these tubule structures is a fundamental process in most organisms. The goal of this work is to get a better understanding ...

  1. Biology Division progress report, October 1, 1991--September 30, 1993

    SciTech Connect (OSTI)

    Hartman, F.C.; Cook, J.S.

    1993-10-01T23:59:59.000Z

    This Progress Report summarizes the research endeavors of the Biology Division of the Oak Ridge National Laboratory during the period October 1, 1991, through September 30, 1993. The report is structured to provide descriptions of current activities and accomplishments in each of the Division`s major organizational units. Lists of information to convey the entire scope of the Division`s activities are compiled at the end of the report.

  2. Prediction of parallel in-register amyloidogenic beta-structures In highly beta-rich protein sequences by pairwise propensity analysis

    E-Print Network [OSTI]

    Bryan, Allen Wayne

    2009-01-01T23:59:59.000Z

    Amyloids and prion proteins are clinically and biologically important beta-structures, whose supersecondary structures are difficult to determine by standard experimental or computational means. In addition, significant ...

  3. Size structuring of planktonic communities : biological rates and ecosystem dynamics

    E-Print Network [OSTI]

    Taniguchi, Darcy Anne Akiko

    2013-01-01T23:59:59.000Z

    Kohfeld, L. Legendre, M. Manizza, T. Platt, R. B. Rivkin, S.J. J. Cullen, B. Irwin, and T. Platt. 1983. AutotrophicMol. Biol. Rev. 63:106- Platt, T. , and K. Denman. 1977.

  4. The Biological Implications of the PP2A Crystal Structure

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    (regulator), is shown in stick representation. The "top" view shows that the C-terminal tail of the C subunit resides on the interface between the A and B subunits where it...

  5. Structural Biology | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over OurTheBrookhaven NationalRegionals » High School Rules, Forms,Science

  6. Electronic Structure and Excited State Dynamics in Biological and Nanoscale

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisitingContractElectron-State Hybridization in Heavy-FermionSystems | MIT-Harvard

  7. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of ScienceandMesa del SolStrengthening a solidSynthesis of 2Dand Water |1Benefits of 3D vs. 2D

  8. Theoretical Physics in Cellular Biology

    E-Print Network [OSTI]

    Theoretical Physics in Cellular Biology: Some Illustrative Case Studies Living matter obeys the laws of physics, and the principles and methods of theoretical physics ought to find useful application observation, I will describe a few specific instances where approaches inspired by theoretical physics allow

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    E-Print Network [OSTI]

    Walter, M.Todd

    DEGREE REQUIREMENTS BIOLOGICAL ENGINEERING TECHNOLOGY ENVIRONMENTAL ENGINEERING TECHNOLOGY The curriculum in the technology programs must satisfy the College of Agriculture and Life Sciences (CALS for the technology programs are listed by subject matter in three major categories: (A) Basic Subjects, (B) Advanced

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    E-Print Network [OSTI]

    · Techno-Economic Analysis of H2 Production by Gasification of Biomass · Renewables Analysis · BiomassWithCarbonSequestration Biomass Hydro Wind Solar Coal Nuclear Natural Gas Oil Biological- and Biomass- Based Hydrogen Production RoxanneRoxanne DanzDanz #12;Barriers Hydrogen Production from Biomass

  11. Biological Impacts of Climate Change

    E-Print Network [OSTI]

    McCarty, John P.

    Biological Impacts of Climate Change John P McCarty, University of Nebraska at Omaha, Omaha, NE and reproduction depend on how well adapted individuals are to local climate patterns. Climate change can disrupt subsequent impacts on populations or species' distributions across geographic regions. Climate change may

  12. Theory in Biology available light

    E-Print Network [OSTI]

    Nowak, Martin A.

    Magazine R406 Theory in Biology Theory is available light Martin A. Nowak Many people praise Gregor the neutral theory of evolution, which assumes that the overwhelming majority of molecular mutations do assume the neutral theory is correct. In a brilliant PhD thesis submitted in 1964, Bill Hamilton

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    E-Print Network [OSTI]

    Goldschmidt, Christina

    & stochastic grammars 7.11 RNA structures 9.11 Finding signals in sequences 14.11 Challenges in genome of structure & movements & shapes & grammars 28.11 Integrative genomics: the omics DNA mRNA Protein Metabolite Phenotype 30.11 Integrative genomics: mapping #12;Computational Biology and Bioinformatics 10.10 Models

  14. Structuring Structural Operational

    E-Print Network [OSTI]

    Mousavi, Mohammad

    aan de Technische Universiteit Eindhoven, op gezag van de Rector Magnificus, prof.dr.ir. C.J. van.A. Reniers CIPDATA LIBRARY TECHNISCHE UNIVERSITEIT EINDHOVEN Mousavi, MohammadReza Structuring Structural Operational Semantics / MohammadReza Mousavi. Eindhoven : Technische Universiteit Eindhoven, 2005

  15. Structuring Structural Operational

    E-Print Network [OSTI]

    Reniers, Michel

    aan de Technische Universiteit Eindhoven, op gezag van de Rector Magnificus, prof.dr.ir. C.J. van.A. Reniers CIP-DATA LIBRARY TECHNISCHE UNIVERSITEIT EINDHOVEN Mousavi, MohammadReza Structuring Structural Operational Semantics / MohammadReza Mousavi. - Eindhoven : Technische Universiteit Eindhoven, 2005

  16. Invited Review Article: Advanced light microscopy for biological space research

    SciTech Connect (OSTI)

    De Vos, Winnok H., E-mail: winnok.devos@uantwerpen.be [Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp (Belgium); Cell Systems and Imaging Research Group, Department of Molecular Biotechnology, Ghent University, Ghent (Belgium); Beghuin, Didier [Lambda-X, Nivelles (Belgium); Schwarz, Christian J. [European Space Agency (ESA), ESTEC, TEC-MMG, Noordwijk (Netherlands); Jones, David B. [Institute for Experimental Orthopaedics and Biomechanics, Philipps University, Marburg (Germany); Loon, Jack J. W. A. van [Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center and Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam, Amsterdam (Netherlands); Bereiter-Hahn, Juergen; Stelzer, Ernst H. K. [Physical Biology, BMLS (FB15, IZN), Goethe University, Frankfurt am Main (Germany)

    2014-10-15T23:59:59.000Z

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  17. Department of Biology -Committees and Representatives

    E-Print Network [OSTI]

    Simons Biology Safety Committee Dave Omond Ed Bruggink Jim Cheetham (Chair) Mike Weber Biology Space Committee Jim Cheetham (Chair) Mike Weber Tom Sherratt Ed Bruggink Curriculum Committee (elected) Tom

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    effectively to constructive feedback. Job Prospects for Biology Graduates MS in Biology Bioremediation Biotechnology Medical Research Industry Government Education Microbiology Health Professions Research Health Food Production Pollution Control Environmental Diagnostics Forestry Agriculture #12;APPENDIX B

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    Artomov, Maksym

    2010-01-01T23:59:59.000Z

    Majority of biological processes can not be described deterministically. Multple levels of regulation contribute to the noise in the observable properties of the cells: fluctuations are ubiquitous in biological networks ...

  20. Foundational platform for mammalian synthetic biology

    E-Print Network [OSTI]

    Davidsohn, Noah (Noah Justin)

    2013-01-01T23:59:59.000Z

    The emergent field of synthetic biology is different from many other biological engineering efforts, in that its roots, design principles, and forward engineering perspective have been adopted from electrical engineering ...

  1. Abiotic and Biological Transformation of Tetraalkoxysilanes

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    Semprini, Lewis

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    E-Print Network [OSTI]

    Rosenberg, Noah

    , Life Sciences Institute and Center for Computational Medicine & Bioinformatics, University of Michigan Education 2001-2005 University of Southern California, Postdoc, Molecular and Computational Biology 1998, BMC Bioinformatics 2010- Editorial Board Member, Human Biology 2010- Associate Editor, Genetics 2009

  3. Autonomous observations of the ocean biological carbon pump

    E-Print Network [OSTI]

    Bishop, James K.B.

    2009-01-01T23:59:59.000Z

    efficiency of biological pump in the global ocean. JournalOcean Biological Carbon Pump Carbon Flux Exploreroceans biological carbon pump (Broecker and Peng, 1982;

  4. advanced molecular biology: Topics by E-print Network

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    311 Biology and Medicine Websites Summary: Molecular Biology Biology 311 Fall 2013 Syllabus Instructor: Dr. Deborah Lycan Class: MWF 9@lclark.edu Website: http:...

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    Biological Inventory of the Colorado Canyons National Conservation Area Prepared by: Joe Stevens .............................. 12 Identify Targeted Inventory Areas

  8. Bridging gaps in synthetic biology oversight : iGEM as a testbed for proactive, adaptive risk management

    E-Print Network [OSTI]

    McNamara, Julie H. (Julie Hutton)

    2014-01-01T23:59:59.000Z

    On the surface, the emerging field of synthetic biology looks highly similar to that of genetic engineering. However, the two fields are based upon divergent underlying logic structures. Whereas genetic engineering affects ...

  9. A Biological Inventory and Conservation Recommendations

    E-Print Network [OSTI]

    A Biological Inventory and Conservation Recommendations for the Great Sand Dunes and San Luis Lakes General Services Building Ft. Collins, Colorado 80523 March 1999 i #12;A Biological Inventory PROGRAM SAGUACHE, COLORADO P.O. Box 674, Saguache, Colorado 81149 ii #12;Biological Inventory of the Great

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    Steiner, Ullrich

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    of modeling, abstraction, and control of a biological system, namely, the lactose regulation systemSPECIAL ISSUE ON SYSTEMS BIOLOGY, JANUARY 2008 51 Stochastic Modeling and Control of Biological for stochastic modeling, model abstraction, and controller design for a biological system. The first half

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    Mayfield, John

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    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    Ecology and Evolutionary Biology The Wiess School of Natural Sciences Chair Evan Siemann Professors of Ecology and Evolutionary Biologyoffersabroadrangeofcoursesinthebiosciences:animalbehavior,animal biology, bioinformatics, conservation biology, diseases, ecology, evolutionary biology, field ecology, genetics, genomics

  2. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.: Davis, J.C.; Stanker, L.H.

    1993-05-11T23:59:59.000Z

    A method is disclosed of quantifying molecules in biological substances, comprising: selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere; preparing a long-lived radioisotope labeled reactive chemical specie; administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system; allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host; isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources; converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation; and measuring the radioisotope concentration in the material by means of direct isotopic counting.

  3. Removal design report for the 108-F Biological Laboratory

    SciTech Connect (OSTI)

    NONE

    1997-09-01T23:59:59.000Z

    Most of the 100-F facilities were deactivated with the reactor and have since been demolished. Of the dozen or so reactor-related structures, only the 105-F Reactor Building and the 108-F Biology Laboratory remain standing today. The 108-F Biology Laboratory was intended to be used as a facility for the mixing and addition of chemicals used in the treatment of the reactor cooling water. Shortly after F Reactor began operation, it was determined that the facility was not needed for this purpose. In 1949, the building was converted for use as a biological laboratory. In 1962, the lab was expanded by adding a three-story annex to the original four-story structure. The resulting lab had a floor area of approximately 2,883 m{sup 2} (main building and annex) that operated until 1973. The building contained 47 laboratories, a number of small offices, a conference room, administrative section, lunch and locker rooms, and a heavily shielded, high-energy exposure cell. The purpose of this removal design report is to establish the methods of decontamination and decommissioning and the supporting functions associated with facility removal and disposal.

  4. Novel nuclear magnetic resonance techniques for studying biological molecules

    SciTech Connect (OSTI)

    Laws, David D.

    2000-06-01T23:59:59.000Z

    Over the fifty-five year history of Nuclear Magnetic Resonance (NMR), considerable progress has been made in the development of techniques for studying the structure, function, and dynamics of biological molecules. The majority of this research has involved the development of multi-dimensional NMR experiments for studying molecules in solution, although in recent years a number of groups have begun to explore NMR methods for studying biological systems in the solid-state. Despite this new effort, a need still exists for the development of techniques that improve sensitivity, maximize information, and take advantage of all the NMR interactions available in biological molecules. In this dissertation, a variety of novel NMR techniques for studying biomolecules are discussed. A method for determining backbone ({phi}/{psi}) dihedral angles by comparing experimentally determined {sup 13}C{sub a}, chemical-shift anisotropies with theoretical calculations is presented, along with a brief description of the theory behind chemical-shift computation in proteins and peptides. The utility of the Spin-Polarization Induced Nuclear Overhauser Effect (SPINOE) to selectively enhance NMR signals in solution is examined in a variety of systems, as are methods for extracting structural information from cross-relaxation rates that can be measured in SPINOE experiments. Techniques for the production of supercritical and liquid laser-polarized xenon are discussed, as well as the prospects for using optically pumped xenon as a polarizing solvent. In addition, a detailed study of the structure of PrP 89-143 is presented. PrP 89-143 is a 54 residue fragment of the prion proteins which, upon mutation and aggregation, can induce prion diseases in transgenic mice. Whereas the structure of the wild-type PrP 89-143 is a generally unstructured mixture of {alpha}-helical and {beta}-sheet conformers in the solid state, the aggregates formed from the PrP 89-143 mutants appear to be mostly {beta}-sheet.

  5. Eric Bennett Computational Molecular Biology

    E-Print Network [OSTI]

    and secondary structure elements to predict a protein's propensity to form amyloids. Introduction Protein to a common feature. These aggregation prone proteins are normally soluble with a variety of three-dimensional to amyloid formation (7-9). Amyloid fibrils have an extremely characteristic structure in which

  6. Biology Division. Progress report, August 1, 1982-September 30, 1983

    SciTech Connect (OSTI)

    Not Available

    1984-01-01T23:59:59.000Z

    The Biology Division is the component of the Oak Ridge National Laboratory that investigates the potential adverse health effects of energy-related substances. The body of this report provides summaries of the aims, scope and progress of the research of groups of investigators in the Division during the period of August 1, 1982, through September 30, 1983. At the end of each summary is a list of publications covering the same period (published or accepted for publication). For convenience, the summaries are assembled under Sections in accordance with the current organizational structure of the Biology Division; each Section begins with an overview. It will be apparent, however, that currents run throughout the Division and that the various programs support and interact with each other.

  7. First Passage Problems in Biology

    E-Print Network [OSTI]

    Tom Chou; Maria R. D'Orsogna

    2014-08-20T23:59:59.000Z

    Applications of first passage times in stochastic processes arise across a wide range of length and time scales in biological settings. After an initial technical overview, we survey representative applications and their corresponding models. Within models that are effectively Markovian, we discuss canonical examples of first passage problems spanning applications to molecular dissociation and self-assembly, molecular search, transcription and translation, neuronal spiking, cellular mutation and disease, and organismic evolution and population dynamics. In this last application, a simple model for stem-cell ageing is presented and some results derived. Various approximation methods and the physical and mathematical subtleties that arise in the chosen applications are also discussed.

  8. Systems biology of Microbial Communities

    SciTech Connect (OSTI)

    Navid, A; Ghim, C; Fenley, A; Yoon, S; Lee, S; Almaas, E

    2008-04-11T23:59:59.000Z

    Microbes exist naturally in a wide range of environments, spanning the extremes of high acidity and high temperature to soil and the ocean, in communities where their interactions are significant. We present a practical discussion of three different approaches for modeling microbial communities: rate equations, individual-based modeling, and population dynamics. We illustrate the approaches with detailed examples. Each approach is best fit to different levels of system representation, and they have different needs for detailed biological input. Thus, this set of approaches is able to address the operation and function of microbial communities on a wide range of organizational levels.

  9. Biological Safety | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergyandapproximately 10 wt%inand FuelBiological

  10. Computational Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would like submit theInnovationComputational Biology SHARE Computational

  11. Green Biologics | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are8COaBulkTransmissionSitingProcess.pdfGetec AG Contracting JumpGoveNebraska:Ethanol LLC GO EthanolBiologics Jump to:

  12. Biological Applications of Synchrotron Radiation:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProduction PetraBiological

  13. Metal?organic frameworks for the storage and delivery of biologically active hydrogen sulfide

    SciTech Connect (OSTI)

    Allan, Phoebe K.; Wheatley, Paul S.; Aldous, David; Mohideen, M. Infas; Tang, Chiu; Hriljac, Joseph A.; Megson, Ian L.; Chapman, Karena W.; De Weireld, Guy; Vaesen, Sebastian; Morris, Russell E. (St Andrews)

    2012-04-02T23:59:59.000Z

    Hydrogen sulfide is an extremely toxic gas that is also of great interest for biological applications when delivered in the correct amount and at the desired rate. Here we show that the highly porous metal-organic frameworks with the CPO-27 structure can bind the hydrogen sulfide relatively strongly, allowing the storage of the gas for at least several months. Delivered gas is biologically active in preliminary vasodilation studies of porcine arteries, and the structure of the hydrogen sulfide molecules inside the framework has been elucidated using a combination of powder X-ray diffraction and pair distribution function analysis.

  14. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  15. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2006-01-24T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

  16. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  17. Grand Challenges for Biological and Environmental Research: A Long-Term Vision

    SciTech Connect (OSTI)

    Arkin, A.; Baliga, N.; Braam, J.; Church, G.; Collins, J; Cottingham, R.; Ecker, J.; Gerstein, M.; Gilna, P.; Greenberg, J.; Handelsman, J.; Hubbard, S.; Joachimiak, A.; Liao, J.; Looger, L.; Meyerowitz, E.; Mjolness, E.; Petsko, G.; Sayler, G.; Simpson, M.; Stacey, G.; Sussman, M.; Tiedje, J.; Bader, D.; Cessi, P.; Collins, W.; Denning, S.; Dickinson, R.; Easterling, D.; Edmonds, J.; Feddema, J.; Field, C.; Fridlind, A.; Fung, I.; Held, I.; Jackson, R.; Janetos, A.; Large, W.; Leinen, M.; Leung, R.; Long, S.; Mace, G.; Masiello, C.; Meehl, G.; Ort, D.; Otto-Bliesner, B.; Penner, J.; Prather, M.; Randall, D.; Rasch, P.; Schneider, E.; Shugart, H.; Thornton, P.; Washington, W.; Wildung, R.; Wiscombe, W.; Zak, D.; Zhang, M.; Bielicki, J.; Buford, M.; Cleland, E.; Dale, V.; Duke, C.; Ehleringer, J.; Hecht, A.; Kammen, D.; Marland, G.; Pataki, D.; Riley, M. Robertson, P.; Hubbard, S.

    2010-12-01T23:59:59.000Z

    The interactions and feedbacks among plants, animals, microbes, humans, and the environment ultimately form the world in which we live. This world is now facing challenges from a growing and increasingly affluent human population whose numbers and lifestyles are driving ever greater energy demand and impacting climate. These and other contributing factors will make energy and climate sustainability extremely difficult to achieve over the 20-year time horizon that is the focus of this report. Despite these severe challenges, there is optimism that deeper understanding of our environment will enable us to mitigate detrimental effects, while also harnessing biological and climate systems to ensure a sustainable energy future. This effort is advanced by scientific inquiries in the fields of atmospheric chemistry and physics, biology, ecology, and subsurface science - all made possible by computing. The Office of Biological and Environmental Research (BER) within the Department of Energy's (DOE) Office of Science has a long history of bringing together researchers from different disciplines to address critical national needs in determining the biological and environmental impacts of energy production and use, characterizing the interplay of climate and energy, and collaborating with other agencies and DOE programs to improve the world's most powerful climate models. BER science focuses on three distinct areas: (1) What are the roles of Earth system components (atmosphere, land, oceans, sea ice, and the biosphere) in determining climate? (2) How is the information stored in a genome translated into microbial, plant, and ecosystem processes that influence biofuel production, climate feedbacks, and the natural cycling of carbon? (3) What are the biological, geochemical, and physical forces that govern the behavior of Earth's subsurface environment? Ultimately, the goal of BER science is to support experimentation and modeling that can reliably predict the outcomes and behaviors of complex biological and environmental systems, leading to robust solutions for DOE missions and strategic goals. In March 2010, the Biological and Environmental Research Advisory Committee held the Grand Challenges for Biological and Environmental Research: A Long-Term Vision workshop to identify scientific opportunities and grand challenges for BER science in the coming decades and to develop an overall strategy for drafting a long-term vision for BER. Key workshop goals included: (1) Identifying the greatest scientific challenges in biology, climate, and the environment that DOE will face over a 20-year time horizon. (2) Describing how BER should be positioned to address those challenges. (3) Determining the new and innovative tools needed to advance BER science. (4) Suggesting how the workforce of the future should be trained in integrative system science. This report lays out grand research challenges for BER - in biological systems, climate, energy sustainability, computing, and education and workforce training - that can put society on a path to achieve the scientific evidence and predictive understanding needed to inform decision making and planning to address future energy needs, climate change, water availability, and land use.

  18. Electrostatic thin film chemical and biological sensor

    DOE Patents [OSTI]

    Prelas, Mark A. (Columbia, MO); Ghosh, Tushar K. (Columbia, MO); Tompson, Jr., Robert V. (Columbia, MO); Viswanath, Dabir (Columbia, MO); Loyalka, Sudarshan K. (Columbia, MO)

    2010-01-19T23:59:59.000Z

    A chemical and biological agent sensor includes an electrostatic thin film supported by a substrate. The film includes an electrostatic charged surface to attract predetermined biological and chemical agents of interest. A charge collector associated with said electrostatic thin film collects charge associated with surface defects in the electrostatic film induced by the predetermined biological and chemical agents of interest. A preferred sensing system includes a charge based deep level transient spectroscopy system to read out charges from the film and match responses to data sets regarding the agents of interest. A method for sensing biological and chemical agents includes providing a thin sensing film having a predetermined electrostatic charge. The film is exposed to an environment suspected of containing the biological and chemical agents. Quantum surface effects on the film are measured. Biological and/or chemical agents can be detected, identified and quantified based on the measured quantum surface effects.

  19. Functional quantum biology in photosynthesis and magnetoreception

    E-Print Network [OSTI]

    Lambert, Neill; Cheng, Yuan-Chung; Li, Che-Ming; Chen, Guang-Yin; Nori, Franco

    2012-01-01T23:59:59.000Z

    Is there a functional role for quantum mechanics or coherent quantum effects in biological processes? While this question is as old as quantum theory, only recently have measurements on biological systems on ultra-fast time-scales shed light on a possible answer. In this review we give an overview of the two main candidates for biological systems which may harness such functional quantum effects: photosynthesis and magnetoreception. We discuss some of the latest evidence both for and against room temperature quantum coherence, and consider whether there is truly a functional role for coherence in these biological mechanisms. Finally, we give a brief overview of some more speculative examples of functional quantum biology including the sense of smell, long-range quantum tunneling in proteins, biological photoreceptors, and the flow of ions across a cell membrane.

  20. Functional quantum biology in photosynthesis and magnetoreception

    E-Print Network [OSTI]

    Neill Lambert; Yueh-Nan Chen; Yuan-Chung Cheng; Che-Ming Li; Guang-Yin Chen; Franco Nori

    2012-05-04T23:59:59.000Z

    Is there a functional role for quantum mechanics or coherent quantum effects in biological processes? While this question is as old as quantum theory, only recently have measurements on biological systems on ultra-fast time-scales shed light on a possible answer. In this review we give an overview of the two main candidates for biological systems which may harness such functional quantum effects: photosynthesis and magnetoreception. We discuss some of the latest evidence both for and against room temperature quantum coherence, and consider whether there is truly a functional role for coherence in these biological mechanisms. Finally, we give a brief overview of some more speculative examples of functional quantum biology including the sense of smell, long-range quantum tunneling in proteins, biological photoreceptors, and the flow of ions across a cell membrane.

  1. Turbo-Decoding RNA Secondary Structure Turbo-Decoding of RNA Secondary Structure

    E-Print Network [OSTI]

    Sharma, Gaurav

    Background Turbo-Decoding RNA Secondary Structure References Turbo-Decoding of RNA Secondary and Computational Biology June 18, 2013 1 #12;Outline Turbo-decoding in Communications: A Quick Review #12;Outline Turbo-decoding in Communications: A Quick Review RNA Structure Analysis: Motivation and Background RNA

  2. A national facility for biological cryo-electron microscopy

    SciTech Connect (OSTI)

    Saibil, Helen R., E-mail: h.saibil@mail.cryst.bbk.ac.uk [Birkbeck College, Malet Street, London WC1E 7HX (United Kingdom); Grnewald, Kay [University of Oxford, Oxford OX3 7BN (United Kingdom); Stuart, David I. [University of Oxford, Oxford OX3 7BN (United Kingdom); Diamond Light Source, Didcot OX11 0DE (United Kingdom); Birkbeck College, Malet Street, London WC1E 7HX (United Kingdom)

    2015-01-01T23:59:59.000Z

    This review provides a brief update on the use of cryo-electron microscopy for integrated structural biology, along with an overview of the plans for the UK national facility for electron microscopy being built at the Diamond synchrotron. Three-dimensional electron microscopy is an enormously powerful tool for structural biologists. It is now able to provide an understanding of the molecular machinery of cells, disease processes and the actions of pathogenic organisms from atomic detail through to the cellular context. However, cutting-edge research in this field requires very substantial resources for equipment, infrastructure and expertise. Here, a brief overview is provided of the plans for a UK national three-dimensional electron-microscopy facility for integrated structural biology to enable internationally leading research on the machinery of life. State-of-the-art equipment operated with expert support will be provided, optimized for both atomic-level single-particle analysis of purified macromolecules and complexes and for tomography of cell sections. The access to and organization of the facility will be modelled on the highly successful macromolecular crystallography (MX) synchrotron beamlines, and will be embedded at the Diamond Light Source, facilitating the development of user-friendly workflows providing near-real-time experimental feedback.

  3. Situs: A Package for Docking Crystal Structures into Low-Resolution Maps from Electron Microscopy

    E-Print Network [OSTI]

    Wriggers, Willy

    of the underlying structural data. 1999 Academic Press Key Words: topology representing neural net- works of visualization in structural biology is currently expanding, as novel modeling and graphics tools begin

  4. Improvement in mechanical properties through structural hierarchies in bio-inspired materials

    E-Print Network [OSTI]

    Sen, Dipanjan, 1980-

    2011-01-01T23:59:59.000Z

    Structural biological materials such as bone, nacre, insect cuticle, and sea sponge exoskeleton showcase the use of inferior building blocks like proteins and minerals to create structures that afford load-bearing and armor ...

  5. Molecular biology of signal transduction in plants

    SciTech Connect (OSTI)

    Not Available

    1991-01-01T23:59:59.000Z

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  6. Innovative Breakthrough Demonstrated for Biological Ethanol Production...

    Office of Environmental Management (EM)

    for Biological Ethanol Production June 30, 2015 - 11:43am Addthis Advanced Biofuels Process Demonstration Unit at Lawrence Berkeley National Laboratory. Photo credit:...

  7. Carbonic Acid Shows Promise in Geology, Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Surprising Secrets of Carbonic Acid Probing the Surprising Secrets of Carbonic Acid Berkeley Lab Study Holds Implications for Geological and Biological Processes October 23,...

  8. Biological Survey of the Upper Purgatoire Watershed

    E-Print Network [OSTI]

    Biological Survey of the Upper Purgatoire Watershed Las Animas County, CO John Carney Colorado ...............................................................................................................9 Management Urgency Ranks ........................................................................................................10 POTENTIAL CONSERVATION SITE PLANNING BOUNDARIES........................................12 Off

  9. STRUCTURE PREDICTION CASP AND OTHER COMMUNITY-WIDE

    E-Print Network [OSTI]

    Bourne, Philip E.

    Section VI STRUCTURE PREDICTION #12;#12;28 CASP AND OTHER COMMUNITY-WIDE ASSESSMENTS TO ADVANCE THE FIELD OF STRUCTURE PREDICTION Jenny Gu and Philip E. Bourne A MEASURE FOR SUCCESS In the early 1990s to the biological community and to measure the progress in this developing field of structure prediction. In part

  10. architecture collagen structure: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Stability Biology and Medicine Websites Summary: Collagen Structure and Stability Matthew D. Shoulders1 and Ronald T. Raines1,2 1 Department play a key role in that stability. The...

  11. Biological and chemical technologies research. FY 1995 annual summary report

    SciTech Connect (OSTI)

    None

    1996-03-01T23:59:59.000Z

    The annual summary report presents the fiscal year (FY) 1995 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program. This BCTR program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1995 (ASR 95) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1995; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents; and awards arising from work supported by the BCTR.

  12. Plant Species Biology (2003) 18, 123127 2003 The Society for the Study of Species Biology

    E-Print Network [OSTI]

    Tomimatsu,, Hiroshi

    2003-01-01T23:59:59.000Z

    and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, JapanPlant Species Biology (2003) 18, 123127 2003 The Society for the Study of Species Biology Blackwell Science, LtdOxford, UKPSBPlant Species Biology1442-1984The Society for the Study of Species

  13. Biological Hydrogen Production Using a Membrane Bioreactor

    E-Print Network [OSTI]

    Biological Hydrogen Production Using a Membrane Bioreactor Sang-Eun Oh,1 Prabha Iyer,1,2 Mary Ann bioreactor (MBR) for biological hydrogen production. The reactor was fed glucose (10,000 mg/L) and inoculated were used. B 2004 Wiley Periodicals, Inc. Keywords: membrane bioreactor; hydrogen production

  14. Southeastern Colorado Survey of Critical Biological Resources

    E-Print Network [OSTI]

    Southeastern Colorado Survey of Critical Biological Resources 2007 #12;ii #12;Southeastern Colorado Survey of Critical Biological Resources Prepared for: Colorado Cattleman's Agricultural Land Trust 8833 Department of Natural Resources Division of State Board of Land Commissioners 1313 Sherman Street Denver, CO

  15. Book Review Geothermal Biology and Geochemis-

    E-Print Network [OSTI]

    Book Review Geothermal Biology and Geochemis- try in Yellowstone National Park. (eds WP Inskeep of life. The legacy of chemical and biologi- cal research in geothermal regimes, while short in duration geothermal areas, including Yellowstone, are largely confined to the specialty literature of geochemical

  16. STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS

    E-Print Network [OSTI]

    STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted to the Office of Graduate Studies Head of Department, Valerie Taylor December 2005 Major Subject: Computer Science #12;iii ABSTRACT

  17. Bi23 BIOLOGY TUTORIALS WINTER TERM 2014

    E-Print Network [OSTI]

    Low, Steven H.

    Bi23 BIOLOGY TUTORIALS WINTER TERM 2014 SECTIONS 1 3 The Function and Regulation of Sleep (3. Huang, x3446, MC 156-29 #12;Bi23 BIOLOGY TUTORIALS WINTER TERM 2014 SECTIONS 4-6 Physical Principles crystallography and neutron scattering; nuclear magnetic resonance and magnetic resonance imaging; peptide and DNA

  18. Genome Biology 2005, 6:312 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Kellis, Manolis

    Genome Biology 2005, 6:312 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch Meeting report Large-scale discovery and validation of functional elements in the human genome-mail: bbernst@fas.harvard.edu. Manolis Kellis. E-mail: manoli@mit.edu Published: 1 March 2005 Genome Biology

  19. Genome Biology 2006, 7:320 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Pritham, Ellen J.

    Genome Biology 2006, 7:320 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch Meeting report Mobile DNA: genomes under the influence Cdric Feschotte and Ellen J Pritham Feschotte. Email: cedric@uta.edu Published: 30 June 2006 Genome Biology 2006, 7:320 (doi:10.1186/gb-2006

  20. FINAL REPORT FOR: OPTIMIZATION OF BIOLOGICAL

    E-Print Network [OSTI]

    AND SUSPENDED GROWTH WASTEWATER TREATMENT SYSTEM DECEMBER, 1994 Prepared for: Environment Canada Environment#12;FINAL REPORT FOR: OPTIMIZATION OF BIOLOGICAL PHOSPHORUS AND AMMONIA REMOVAL IN A COMBINED FIXED;Optimization of Biological Phosphorus and Ammonia Removal in a Combined Fixed & Suspended Growth System i

  1. Waste Handling and Disposal Biological Safety

    E-Print Network [OSTI]

    Pawlowski, Wojtek

    plumbing services, EHS personnel wastewater treatment plant personnel, and the general public canWaste Handling and Disposal Biological Safety General Biosafety Practices (GBP) Why You Should Care on the next experiment. Are you working with r/sNA, biological toxins, human materials, needles, plasticware

  2. Biology and Medicine Division annual report, 1981-1982. [Lead abstract

    SciTech Connect (OSTI)

    Not Available

    1983-04-01T23:59:59.000Z

    Separate abstracts were prepared for the 61 research reports in the 1981-1982 annual report for the Biology and Medicine Division of the Lawrence Berkeley Laboratory. Programs reviewed include research medicine, Donner Pavilion, environmental physiology, radiation biophysics and structural biophysics. (KRM)

  3. Custom Device for Low-Dose Gamma Irradiation of Biological Samples

    E-Print Network [OSTI]

    Bi, Ruoming

    2012-02-14T23:59:59.000Z

    , the structural material is efficient to absorb most of the cosmic-ray energy and reduce the interior dose rate to below 1.2 mGy per day. However, the biological effects of prolonged exposure to low-dose radiation are not well understood. The purpose...

  4. Biological Interaction Networks Based on Sparse Temporal Expansion of Graphical Models

    E-Print Network [OSTI]

    Garofalakis, Minos

    . This problem has two aspects. Firstly, the lack of features experimental samples (genes/proteins) when in the context of gene and protein sequence analysis in molecular biology. Microarrays and proteomics technology compared to the number of observed genes/proteins makes the inference of the network structure quite

  5. On-line tools for sequence retrieval and multivariate statistics in molecular biology

    E-Print Network [OSTI]

    Thioulouse, Jean

    On-line tools for sequence retrieval and multivariate statistics in molecular biology Guy Perrire@biomserv.univ-lyon1.fr Keywords: World-Wide Web; Sequence data banks; Retrieval system; Multivariateanalysis; Sequence for browsing sequence collections structured under ACNUC format and for performing multivariate analyses

  6. Molecular Biology of the Cell Vol. 20, 13401347, March 1, 2009

    E-Print Network [OSTI]

    Boyer, Edmond

    , bo Akademi University, 20520 Turku, Finland; Departments of Biochemistry and Pharmacy and Biology to satellite III DNA in nuclear stress bodies, subnuclear structures in which HSF1 induces transcription to Hsps, HSFs are associated with ex- pression of noncoding satellite III (sat III) RNA in nuclear stress

  7. BCTR: Biological and Chemical Technologies Research 1994 annual summary report

    SciTech Connect (OSTI)

    Petersen, G.

    1995-02-01T23:59:59.000Z

    The annual summary report presents the fiscal year (FY) 1994 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). Although the OIT was reorganized in 1991 and AICD no longer exists, this document reports on efforts conducted under the former structure. The annual summary report for 1994 (ASR 94) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1994; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents, and awards arising from work supported by BCTR.

  8. Aspects of the political economy of development and synthetic biology

    E-Print Network [OSTI]

    Wellhausen, Rachel

    What implications might synthetic biologys potential as a wholly new method of production have for the world economy, particularly developing countries? Theories of political economy predict that synthetic biology can ...

  9. ASTRONOMY BIOLOGY CHEMISTRY COMPUTER-SCIENCE GEOGRAPHY MATHEMATICS PHYSICS STATISTICS

    E-Print Network [OSTI]

    Bernstein, Phil

    BIOMEDICAL-ENGINEERING ELECTRONIC- ENGINEERING ASTRONOMY BIOLOGY CHEMISTRY COMPUTER-SCIENCE GEOGRAPHY MATHEMATICS PHYSICS STATISTICS HEALTHCARE BIOMEDICAL-ENGINEERING ELECTRONIC-ENGINEERING ASTRONOMY BIOLOGY C H HEALTHCARE BIOMEDICAL-ENGINEERING ELECTRONIC-ENGINEERING ASTRONOMY BIOLOGY CHEMISTRY COMPUTER

  10. Crafting life : a sensory ethnography of fabricated biologies

    E-Print Network [OSTI]

    Roosth, Hannah Sophia

    2010-01-01T23:59:59.000Z

    This ethnography tracks a diverse set of practices I term "constructive biologies," by which I mean efforts in the post-genomic life sciences to understand how biology works by making new biological things. I examine five ...

  11. What rough beast? Synthetic Biology and the Future of Biosecurity

    E-Print Network [OSTI]

    Mohr, Scott C.

    Synthetic biology seeks to create modular biological parts that can be assembled into useful devices, allowing the modification of biological systems with greater reliability, at lower cost, with greater speed, and by a ...

  12. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.; Davis, J.C.

    1994-12-27T23:59:59.000Z

    Disclosed is a method of quantifying molecules in biological substances comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system, d. allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host, e. isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources, f. converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in the material by means of direct isotopic counting. 5 figures.

  13. Systems Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposed Action(InsertAbout the Geothermal

  14. Microscopic linear liquid streams in vacuum: Injection of solvated biological samples into X-ray free electron lasers

    SciTech Connect (OSTI)

    Doak, R. B.; DePonte, D. P.; Nelson, G.; Camacho-Alanis, F.; Ros, A.; Spence, J. C. H.; Weierstall, U. [Arizona State University, Tempe, AZ 85287-1504 (United States); Centre for Free-Electron Laser Science, DESY, D-22607 Hamburg (Germany); Arizona State University, Tempe, AZ 85287-1504 (United States)

    2012-11-27T23:59:59.000Z

    Microscopic linear liquid free-streams offer a means of gently delivering biological samples into a probe beam in vacuum while maintaining the sample species in a fully solvated state. By employing gas dynamic forces to form the microscopic liquid stream (as opposed to a conventional solid-walled convergent nozzle), liquid free-streams down to 300 nm diameter have been generated. Such 'Gas Dynamic Virtual Nozzles' (GDVN) are ideally suited to injecting complex biological species into an X-ray Free Electron Laser (XFEL) to determine the structure of the biological species via Serial Femtosecond Crystallography (SFX). GDVN injector technology developed for this purpose is described.

  15. Department of Energy's Biological and Environmental Research Strategic Data Roadmap for Earth System Science

    SciTech Connect (OSTI)

    Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Palanisamy, Giri [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Shipman, Galen [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boden, Thomas A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Voyles, Jimmy W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-04-25T23:59:59.000Z

    Rapid advances in experimental, sensor, and computational technologies and techniques are driving exponential growth in the volume, acquisition rate, variety, and complexity of scientific data. This wealth of scientifically meaningful data has tremendous potential to lead to scientific discovery. However, to achieve scientific breakthroughs, these data must be exploitablethey must be analyzed effectively and efficiently and the results shared and communicated easily within the wider Department of Energys (DOEs) Biological and Environmental Research (BER) Climate and Environmental Sciences Division (CESD) community. The explosion in data complexity and scale makes these tasks exceedingly difficult to achieve, particularly given that an increasing number of disciplines are working across techniques, integrating simulation and experimental or observational results (see Table 5 in Appendix 2). Consequently, we need new approaches to data management, analysis, and visualization that provide research teams with easy-to-use and scalable end-to-end solutions. These solutions must facilitate (and where feasible, automate and capture) every stage in the data lifecycle (shown in Figure 1), from collection to management, annotation, sharing, discovery, analysis, and visualization. In addition, the core functionalities are the same across climate science communities, but they require customization to adapt to specific needs and fit into research and analysis workflows. To this end, the mission of CESDs Data and Informatics Program is to integrate all existing and future distributed CESD data holdings into a seamless and unified environment for the acceleration of Earth system science.

  16. Introductory Computing: The Design Discipline

    E-Print Network [OSTI]

    Proulx, Viera K.

    in the context of information systems · Didactics: Systematic problem solving · Didactics: Information and data: the connection · Didactics: Design of abstractions = libraries · Didactics: Libraries for the beginners 2 #12 language context Systematic didactics for program design Connection between information and data Test

  17. Introductory Computing: The Design Discipline

    E-Print Network [OSTI]

    Proulx, Viera K.

    in the context of information systems · Didactics: algebra and programming · Information and data: the connection;6 Simple language context Systematic didactics for program design Connection between information and data with the given (input) data and output data Didactics: Algebra and Programing #12;9 Didactics of the design

  18. Exoplanetary Geophysics -- An Emerging Discipline

    E-Print Network [OSTI]

    Laughlin, Gregory

    2015-01-01T23:59:59.000Z

    Thousands of extrasolar planets have been discovered, and it is clear that the galactic planetary census draws on a diversity greatly exceeding that exhibited by the solar system's planets. We review significant landmarks in the chronology of extrasolar planet detection, and we give an overview of the varied observational techniques that are brought to bear. We then discuss the properties of the currently known distribution, using the mass-period diagram as a guide to delineating hot Jupiters, eccentric giant planets, and a third, highly populous, category that we term "ungiants", planets having masses less than 30 Earth masses and orbital periods less than 100 days. We then move to a discussion of the bulk compositions of the extrasolar planets. We discuss the long-standing problem of radius anomalies among giant planets, as well as issues posed by the unexpectedly large range in sizes observed for planets with masses somewhat greater than Earth's. We discuss the use of transit observations to probe the atmo...

  19. Work Force Discipline--Withdrawn

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2012-04-05T23:59:59.000Z

    Withdrawn 4-26-14. Significant changes from the Order include the deletion of material included in other documents such as statutes and Federal regulations. In addition, an updated Table of Penalties now includes Smoking, Cyber Security, Standards of Conduct or other Ethical Violations, and the incorporation of the Travel and Purchase Card Guidance dated January 2003.

  20. advanced biological treatment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Patrice Ct DALHOUSIE UNIVERSITY 12;BIOL 3020.03 Advanced Cell Biology Syllabus Page 2 Course description For a cell to function Adl, Sina 2 Biological Cybernetics...

  1. XPS Analysis of Nanostructured Materials and Biological Surfaces...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Analysis of Nanostructured Materials and Biological Surfaces. XPS Analysis of Nanostructured Materials and Biological Surfaces. Abstract: This paper examines the types of...

  2. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009)...

  3. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    E-Print Network [OSTI]

    Oldenburg, Curtis M.

    2008-01-01T23:59:59.000Z

    Enhancement of soil carbon sequestration by amendment withBiologically Enhanced Carbon Sequestration: Research Needson Biologically Enhanced Carbon Sequestration, October 29,

  4. A Systems Biology Approach to Infectious Disease Research: Innovating...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm. A Systems Biology Approach to Infectious Disease Research: Innovating the...

  5. Comparative systems biology across an evolutionary gradient within...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    systems biology across an evolutionary gradient within the Shewanella genus . Comparative systems biology across an evolutionary gradient within the Shewanella genus . Abstract: To...

  6. Associate Editor of the ASME Journal of Pressure Vessels Technology, since Jan 2006 Associate Editor of the Structural Health Monitoring: An International Journal , since May

    E-Print Network [OSTI]

    Wong, Pak Kin

    Editor of the Structural Health Monitoring: An International Journal , since May 2008 Advisory Editor to Present Editor of the following Conference Proceedings: 16. Health Monitoring of Structural and Biological 9780819475558, 2009. 14. Health Monitoring of Structural and Biological Systems 2008, Ed. T. Kundu, Pub. SPIE

  7. Biological and Chemical Approaches to Diseases

    E-Print Network [OSTI]

    Morimoto, Richard

    , chaperones, heat shock response, protein folding and misfolding, unfolded protein response Abstract Many that proteostasis is influenced both by an adjustable proteostasis network capacity and protein folding energetics INTRODUCTION . . . . . . . . . . . . . . . . . . 960 PROTEIN FOLDING IN VITRO . . . 961 BIOLOGICALLY ASSISTED

  8. VEHICLE OPERATING PROCEDURES DEPARTMENT OF BIOLOGICAL SCIENCE

    E-Print Network [OSTI]

    Ronquist, Fredrik

    VEHICLE OPERATING PROCEDURES DEPARTMENT OF BIOLOGICAL SCIENCE GENERAL INFORMATION Vehicles resposniblity and disciplinary action. Vehicles may be used by faculty or staff from other departments complete the vehicle usage agreement form certifying that they have a valid driver's license

  9. Technical Working Group on Biological Evidence Preservation

    E-Print Network [OSTI]

    Perkins, Richard A.

    of Forensic Science (AAFS) Annual Meeting Thursday, February 20, 2014 #12;The State of Biological Evidence Dennis Davenport, Senior Crime Scene Investigator, Commerce City PD Rock Harmon, Consultant, DNARock

  10. BIOMEDICAL ENGINEERING CHEMICAL AND BIOLOGICAL ENGINEERING

    E-Print Network [OSTI]

    Heller, Barbara

    BIOMEDICAL ENGINEERING CHEMICAL AND BIOLOGICAL ENGINEERING CIVIL, ARCHITECTURAL, AND ENVIRONMENTAL ENGINEERING ELECTRICAL AND COMPUTER ENGINEERING MECHANICAL, MATERIALS, AND AEROSPACE ENGINEERING COLLEGE OF ENGINEERING IIT ARMOUR #12;WHY ENGINEERINGAT IIT ARMOUR? Five Departments. One Distinctive Educational

  11. BIOLOGICAL & AGRICULTURAL ENGINEERING DEPARTMENT POSITION ANNOUNCEMENT

    E-Print Network [OSTI]

    BIOLOGICAL & AGRICULTURAL ENGINEERING DEPARTMENT POSITION ANNOUNCEMENT Position Title: Assistant/Associate Professor and Extension Specialist (Water/Wastewater Engineering) Appointment: 70% Texas A&M Agri) and other environmental issues of concern to rural communities, agricultural producers, agri

  12. The Biology of Some Kansas Eumenidae

    E-Print Network [OSTI]

    Isely, Dwight

    1913-01-01T23:59:59.000Z

    This paper is based on field observations and collections made by the author while connected with the Biological Survey of the University of Kansas, in Northwestern Kansas, during the summer of 1912. Specimens of fully ...

  13. Stochastic modeling of biological sequence evolution

    E-Print Network [OSTI]

    Xu, Keyuan

    2005-01-01T23:59:59.000Z

    Markov models of sequence evolution are a fundamental building block for making inferences in biological research. This thesis reviews several major techniques developed to estimate parameters of Markov models of sequence ...

  14. Biological applications of weal polyelectrolyte multilayers

    E-Print Network [OSTI]

    Berg, Michael C., Ph. D. Massachusetts Institute of Technology

    2005-01-01T23:59:59.000Z

    This thesis research focused on biological applications of ultra-thin weak polyelectrolyte multilayers with specific emphasis on cell patterning, drug delivery, and antibacterial coatings. All of these very different ...

  15. Genetics and molecular biology of breast cancer

    SciTech Connect (OSTI)

    King, M.C. [California Univ., Berkeley, CA (United States); Lippman, M. [Georgetown Univ. Medical Center, Washington, DC (United States)] [comps.

    1992-12-31T23:59:59.000Z

    This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

  16. Elizabeth R. Dumont Department of Biology

    E-Print Network [OSTI]

    Dumont, Elizabeth R.

    collection on the biology- engineering interface" (P.I.) Direct Costs: $670,425 (includes $7,500 REU, UMass Amherst. 2007 Plenary Speaker, 14th International Bat Research Congress, Merida, Mexico 2006

  17. Complexity and Systems Biology of Microbial Biofuels

    E-Print Network [OSTI]

    Rand, David

    Complexity and Systems Biology of Microbial Biofuels 20-24 June 2011 (All and issues Theme: Biofuel systems and issues (Chair: Nigel Burroughs) 13 (Bielefeld) Biofuels from algae- challenges for industrial levels

  18. TCD-IISc Symposium "Chemistry & Chemical Biology"

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    actinide chemistry, with a focus on coordination and organometallic uranium chemistry. Paula ColavitaTCD-IISc Symposium "Chemistry & Chemical Biology" Trinity College Clive Williams, Dean of Chemistry. Research areas include supramolecular organic and inorganic chemistry and medicinal chemistry

  19. Nanotechnology: emerging tools for biology and medicine

    E-Print Network [OSTI]

    Wong, Ian Y.

    Historically, biomedical research has been based on two paradigms. First, measurements of biological behaviors have been based on bulk assays that average over large populations. Second, these behaviors have then been ...

  20. Statistical methods to infer biological interactions

    E-Print Network [OSTI]

    Tucker, George Jay

    2014-01-01T23:59:59.000Z

    Biological systems are extremely complex, and our ability to experimentally measure interactions in these systems is limited by inherent noise. Technological advances have allowed us to collect unprecedented amounts of raw ...

  1. Size adjustable separation of biologically active molecules

    E-Print Network [OSTI]

    Gutierrez, Mauricio R. (Mauricio Roberto)

    2004-01-01T23:59:59.000Z

    Separation of biologically active molecules (BAM's) is a problem for the pharmaceutical and biotechnology industries. Current technologies addressing this problem require too many techniques, toxic additives, and time to ...

  2. Systems Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposed Action(InsertAbout the Geothermal TechnologiesSystems

  3. APPLICATION FOR STEVENS SCHOLARSHIP Department of Biological Sciences

    E-Print Network [OSTI]

    Rock, Chris

    :_____ Total Credit Hours Completed: __________ Transferred Credit Hours: __________ Biology Quality Points University Course Prefix Course Number Semester Letter Grade Grade Points Biology Quality Points e.g. BIOL 1403 A 4 16 Summed Biology Quality Points: *Biology courses include all with the prefixes: BIOL, BOT

  4. Agricultural & Biological Engineering Alumni Newsletter. Winter 2009 ABE@Illinois

    E-Print Network [OSTI]

    Gilbert, Matthew

    Agricultural & Biological Engineering Alumni Newsletter. Winter 2009 ABE@Illinois WINTER2009 Triple Crown for Illinois's Agricultural and Biological Engineering Program The Agricultural and Biological of Agricultural and Biological Engineering held its first annual "Celebrate ABE@Illinois" on September 5th and 6th

  5. MONOTONE INPUT/OUTPUT SYSTEMS, AND APPLICATIONS TO BIOLOGICAL SYSTEMS

    E-Print Network [OSTI]

    Enciso, Germán

    . iii #12;Preface: From Tycho Brahe To Microarrays How does mathematics fit into modern biology research

  6. 7.012 Introduction to Biology, Fall 2001

    E-Print Network [OSTI]

    Weinberg, Robert A. (Robert Allan), 1942-

    Cell biology, immunology, neurobiology, and an exploration into current research in cancer, genomics, and molecular medicine.

  7. Ninebrane structures

    E-Print Network [OSTI]

    Hisham Sati

    2015-01-16T23:59:59.000Z

    String structures in degree four are associated with cancellation of anomalies of string theory in ten dimensions. Fivebrane structures in degree eight have recently been shown to be associated with cancellation of anomalies associated to the NS5-brane in string theory as well as the M5-brane in M-theory. We introduce and describe "Ninebrane structures" in degree twelve and demonstrate how they capture some anomaly cancellation phenomena in M-theory. Along the way we also define certain variants, considered as intermediate cases in degree nine and ten, which we call "2-Orientation" and "2-Spin structures", respectively. As in the lower degree cases, we also discuss the natural twists of these structures and characterize the corresponding topological groups associated to each of the structures, which likewise admit refinements to differential cohomology.

  8. BIOLOGY INTERNATIONAL The Official Journal of the International Union of Biological Sciences

    E-Print Network [OSTI]

    Slik, Ferry

    , RMIT University School of Civil, Environmental and Chemical Engineering, Building 10, level 12, 376 of Environmental Biology University of Guelph, Guelph, ON N3C 2B7, Canada e-mail: pkevan@uoguelph.ca Nicholas 1TN, UK e-mail: nmt1@cam.ac.uk Ralf Reski, Head, Plant Biotechnology, Faculty of Biology, University

  9. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark E. coli pangenomics - or - How to compare hundreds of E. coli genomes Fuzzy Dave Ussery Ullevl Universitetssykehus Oslo, Norway Wednesday, 10 December, 2008 #12;Comparative Microbial Genomics group Centerfor

  10. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark Burkholderia Pan-genomics Dave Ussery Max Planck Institut fur Terrestrial Microbiology Marburg, Germany 26 May, 2008 - or - What can we learn from more than 50 sequenced genomes? #12;Comparative Microbial Genomics

  11. The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position

    E-Print Network [OSTI]

    The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position We in citizen science projects.The post-doc will join the extended CRI lab that includes synthetic and systems-sourcing, DIY approaches and gamification as part of a new European- funded project, Citizen CyberLab - a three

  12. Methods in Enzymology -submitted 7.28.04, revised 7.30.04, revised 8.02.04 -1-An Integrated Platform for Automated Analysis of Protein NMR Structures

    E-Print Network [OSTI]

    Powers, Robert

    Biology and Biochemistry, and Northeast Structural Genomics Consortium, Rutgers University, Piscataway, NJ 08854 b Ontario Cancer Institute, Department of Medical Biophysics, and Northeast Structural Genomics, Lincoln, NB 68588 d Department of Chemistry, and Northeast Structural Genomics Consortium, University

  13. Quantum metrology and its application in biology

    E-Print Network [OSTI]

    Michael A. Taylor; Warwick P. Bowen

    2014-09-03T23:59:59.000Z

    Quantum metrology provides a route to overcome practical limits in sensing devices. It holds particular relevance in biology, where sensitivity and resolution constraints restrict applications both in fundamental biophysics and in medicine. Here, we review quantum metrology from this biological context. The understanding of quantum mechanics developed over the past century has already enabled important applications in biology, including positron emission tomography (PET) with entangled photons, magnetic resonance imaging (MRI) using nuclear magnetic resonance, and bio-magnetic imaging with superconducting quantum interference devices (SQUIDs). With the birth of quantum information science came the realization that an even greater range of applications arise from the ability to not just understand, but to engineer coherence and correlations in systems at the quantum level. In quantum metrology, quantum coherence and quantum correlations are engineered to enable new approaches to sensing. This review focusses specifically on optical quantum metrology, where states of light that exhibit non-classical photon correlations are used to overcome practical and fundamental constraints, such as the shot-noise and diffraction limits. Recent experiments have demonstrated quantum enhanced sensing of biological systems, and established the potential for quantum metrology in biophysical research. These experiments have achieved capabilities that may be of significant practical benefit, including enhanced sensitivity and resolution, immunity to imaging artifacts, and characterisation of the biological response to light at the single-photon level. New quantum measurement techniques offer even greater promise, raising the prospect for improved multi-photon microscopy and magnetic imaging, among many other possible applications.

  14. Computational Biology and High Performance Computing 2000

    SciTech Connect (OSTI)

    Simon, Horst D.; Zorn, Manfred D.; Spengler, Sylvia J.; Shoichet, Brian K.; Stewart, Craig; Dubchak, Inna L.; Arkin, Adam P.

    2000-10-19T23:59:59.000Z

    The pace of extraordinary advances in molecular biology has accelerated in the past decade due in large part to discoveries coming from genome projects on human and model organisms. The advances in the genome project so far, happening well ahead of schedule and under budget, have exceeded any dreams by its protagonists, let alone formal expectations. Biologists expect the next phase of the genome project to be even more startling in terms of dramatic breakthroughs in our understanding of human biology, the biology of health and of disease. Only today can biologists begin to envision the necessary experimental, computational and theoretical steps necessary to exploit genome sequence information for its medical impact, its contribution to biotechnology and economic competitiveness, and its ultimate contribution to environmental quality. High performance computing has become one of the critical enabling technologies, which will help to translate this vision of future advances in biology into reality. Biologists are increasingly becoming aware of the potential of high performance computing. The goal of this tutorial is to introduce the exciting new developments in computational biology and genomics to the high performance computing community.

  15. Division of Biological and Medical Research annual technical report, 1981

    SciTech Connect (OSTI)

    Rosenthal, M.W. (ed.)

    1982-06-01T23:59:59.000Z

    This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  16. Division of Biological and Medical Research annual technical report 1982

    SciTech Connect (OSTI)

    Rosenthal, M.W. (ed.)

    1983-05-01T23:59:59.000Z

    This report summarizes research during 1982 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Carcinogenesis address mechanisms of chemical and radiation carcinogenesis including the processes of tumor initiation and promotion. The studies employ rat liver and mouse skin models as well as human rodent cell culture systems. The use of liposomes for metal mobilization is also explored. Low Level Radiation studies include delineation of the hematopoietic and other responses of dogs to continuous low level gamma irradiation, comparison of lifetime effects in mice of low level neutron and gamma irradiation, and study of the genetic effects of high LET radiation. Molecular Biology research develops two-dimensional electrophoresis systems for diagnosis and detection of cancer and other diseases. Fundamental structural and biophysical investigations of immunoglobulins and other key proteins are included, as are studies of cell growth, and of molecular and cellular effects of solar uv light. Research in Toxicology uses cellular, physiological, whole animal, and chronobiological end points and chemical separations to elucidate mechanisms and evaluate hazards of coal conversion by-products, actinides, and toxic metals. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  17. Structure, dynamics, and function of biomolecules

    SciTech Connect (OSTI)

    Frauenfelder, H.; Berendzen, J.R.; Garcia, A.; Gupta, G.; Olah, G.A.; Terwilliger, T.C.; Trewhella, J.; Wood, C.C.; Woodruff, W.H.

    1998-11-01T23:59:59.000Z

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The authors enhanced Los Alamos' core competency in Bioscience and Biotechnology by building on present strengths in experimental techniques, theory, high-performance computing, modeling, and simulation applied to biomolecular structure, dynamics, and function. Specifically, the authors strengthened their capabilities in neutron/x-ray scattering, x-ray crystallography, NMR, laser, and optical spectroscopies. Initially they focused on supporting the Los alamos Neutron Science Center (LANSCE) in the design and implementation of new neutron scattering instrumentation, they developed new methods for analysis of scattering data, and they developed new projects to study the structures of biomolecular complexes. The authors have also worked to strengthen interactions between theory and experiment, and between the biological and physical sciences. They sponsored regular meetings of members from all interested LANL technical divisions, and supported two lecture series: ''Biology for Physicists'' and ''Issues in Modern Biology''. They also supported the formation of interdisciplinary/inter-divisional teams to develop projects in science-based bioremediation and an integrated structural biology resource. Finally, they successfully worked with a multidisciplinary team to put forward the Laboratory's Genome and Beyond tactical goal.

  18. Biological imaging by soft x-ray diffraction microscopy

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Shapiro, D. [Stony Brook Univ., Stony Brook, NY (United States); Thibault, P. [Cornell Univ., Ithaca, NY (United States); Beetz, T. [Stony Brook Univ., Stony Brook, NY (United States); Brookhaven National Lab., Upton, NY (United States). Center for Functional Nanomaterials; Elser, V. [Cornell Univ., Ithaca, NY (United States); Howells, M. [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Advanced Light Source; Jacobsen, C. [Stony Brook Univ., Stony Brook, NY (United States); Brookhaven National Lab., Upton, NY (United States). Center for Functional Nanomaterials; Kirz, J. [Stony Brook Univ., Stony Brook, NY (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Advanced Light Source; Lima, E. [Stony Brook Univ., Stony Brook, NY (United States); Miao, H. [Stony Brook Univ., Stony Brook, NY (United States); Neiman, A. M. [State Univ. of New York at Stony Brook, NY (United States); Sayre, D. [Stony Brook Univ., Stony Brook, NY (United States)

    2005-10-25T23:59:59.000Z

    We have used the method of x-ray diffraction microscopy to image the complex-valued exit wave of an intact and unstained yeast cell. The images of the freeze-dried cell, obtained by using 750-eV x-rays from different angular orientations, portray several of the cell's major internal components to 30-nm resolution. The good agreement among the independently recovered structures demonstrates the accuracy of the imaging technique. To obtain the best possible reconstructions, we have implemented procedures for handling noisy and incomplete diffraction data, and we propose a method for determining the reconstructed resolution. This work represents a previously uncharacterized application of x-ray diffraction microscopy to a specimen of this complexity and provides confidence in the feasibility of the ultimate goal of imaging biological specimens at 10-nm resolution in three dimensions.

  19. Biology Division progress report, October 1, 1984-September 30, 1985

    SciTech Connect (OSTI)

    Not Available

    1986-01-01T23:59:59.000Z

    The body of this report provides summaries of the aims, scope and progress of the research by groups of investigators in the Division during the period of October 1, 1984, through September 30, 1985. At the end of each summary is a list of publications covering the same period. For convenience, the summaries are assembled under Sections in accordance with the current organizational structure of the Biology Division; each Section begins with an overview. It will be apparent, however, tha crosscurrents run throughout the Division and that the various programs support and interact with each other. In addition, this report includes information on the Division's educational activities, Advisory Committee, seminar program, and international interactions, as well as extramural activities of staff members, abstracts for technical meetings, and funding and personnel levels.

  20. Critical Waves and the Length Problem of Biology

    E-Print Network [OSTI]

    Laughlin, R B

    2015-01-01T23:59:59.000Z

    It is pointed out that the mystery of how biological systems measure their lengths vanishes away if one premises that they have discovered a way to generate linear waves analogous to compressional sound. These can be used to detect length at either large or small scales using echo timing and fringe counting. It is shown that suitable linear chemical potential waves can, in fact, be manufactured by tuning to criticality conventional reaction-diffusion with a small number substances. Min oscillations in E. coli are cited as precedent resonant length measurement using chemical potential waves analogous to laser detection. Mitotic structures in eucaryotes are identified as candidates for such an effect at higher frequency. The engineering principle is shown to be very general and functionally the same as that used by hearing organs. PNAS Significance Statement: This paper invokes physical principles to address the question of how living things might use reaction-diffusion to measure out and regulate the many thou...

  1. Biological Imaging by Soft X-ray Diffraction Microscopy

    SciTech Connect (OSTI)

    Shapiro,D.; Thibault, P.; Beetz, T.; Elser, V.; Howells, M.; Jacobsen, C.; Kirz, J.; Lima, E.; Miao, H.; et al.

    2005-01-01T23:59:59.000Z

    We have used the method of x-ray diffraction microscopy to image the complex-valued exit wave of an intact and unstained yeast cell. The images of the freeze-dried cell, obtained by using 750-eV x-rays from different angular orientations, portray several of the cell's major internal components to 30-nm resolution. The good agreement among the independently recovered structures demonstrates the accuracy of the imaging technique. To obtain the best possible reconstructions, we have implemented procedures for handling noisy and incomplete diffraction data, and we propose a method for determining the reconstructed resolution. This work represents a previously uncharacterized application of x-ray diffraction microscopy to a specimen of this complexity and provides confidence in the feasibility of the ultimate goal of imaging biological specimens at 10-nm resolution in three dimensions.

  2. The acquisition of dangerous biological materials :

    SciTech Connect (OSTI)

    Aceto, Donato Gonzalo; Astuto-Gribble, Lisa M.; Gaudioso, Jennifer M.

    2007-11-01T23:59:59.000Z

    Numerous terrorist organizations have openly expressed interest in producing and deploying biological weapons. However, a limiting factor for many terrorists has been the acquisition of dangerous biological agents, as evidenced by the very few successful instances of biological weapons use compared to the number of documented hoaxes. Biological agents vary greatly in their ability to cause loss of life and economic damage. Some agents, if released properly, can kill many people and cause an extensive number of secondary infections; other agents will sicken only a small number of people for a short period of time. Consequently, several biological agents can potentially be used to perpetrate a bioterrorism attack but few are likely capable of causing a high consequence event. It is crucial, from a US national security perspective, to more deeply understand the likelihood that terrorist organizations can acquire the range of these agents. Few studies have attempted to comprehensively compile the technical information directly relevant to the acquisition of dangerous bacteria, viruses and toxins. In this report, technical fact sheets were assembled for 46 potentially dangerous biological agents. Much of the information was taken from various research sources which could ultimately and significantly expedite and improve bioterrorism threat assessments. By systematically examining a number of specific agent characteristics included in these fact sheets, it may be possible to detect, target, and implement measures to thwart future terrorist acquisition attempts. In addition, the information in these fact sheets may be used as a tool to help laboratories gain a rudimentary understanding of how attractive a method laboratory theft is relative to other potential acquisition modes.

  3. Quantum Interference in Cognition: Structural Aspects of the Brain

    E-Print Network [OSTI]

    Diederik Aerts; Sandro Sozzo

    2012-04-22T23:59:59.000Z

    We identify the presence of typically quantum effects, namely 'superposition' and 'interference', in what happens when human concepts are combined, and provide a quantum model in complex Hilbert space that represents faithfully experimental data measuring the situation of combining concepts. Our model shows how 'interference of concepts' explains the effects of underextension and overextension when two concepts combine to the disjunction of these two concepts. This result supports our earlier hypothesis that human thought has a superposed two-layered structure, one layer consisting of 'classical logical thought' and a superposed layer consisting of 'quantum conceptual thought'. Possible connections with recent findings of a 'grid-structure' for the brain are analyzed, and influences on the mind/brain relation, and consequences on applied disciplines, such as artificial intelligence and quantum computation, are considered.

  4. Spectroscopic diagnostics for bacteria in biologic sample

    DOE Patents [OSTI]

    El-Sayed, Mostafa A. (Atlanta, GA); El-Sayed, Ivan H. (Somerville, MA)

    2002-01-01T23:59:59.000Z

    A method to analyze and diagnose specific bacteria in a biologic sample using spectroscopy is disclosed. The method includes obtaining the spectra of a biologic sample of a non-infected patient for use as a reference, subtracting the reference from the spectra of an infected sample, and comparing the fingerprint regions of the resulting differential spectrum with reference spectra of bacteria in saline. Using this diagnostic technique, specific bacteria can be identified sooner and without culturing, bacteria-specific antibiotics can be prescribed sooner, resulting in decreased likelihood of antibiotic resistance and an overall reduction of medical costs.

  5. Biology and Medicine Division: Annual report 1986

    SciTech Connect (OSTI)

    Not Available

    1987-04-01T23:59:59.000Z

    The Biology and Medicine Division continues to make important contributions in scientific areas in which it has a long-established leadership role. For 50 years the Division has pioneered in the application of radioisotopes and charged particles to biology and medicine. There is a growing emphasis on cellular and molecular applications in the work of all the Division's research groups. The powerful tools of genetic engineering, the use of recombinant products, the analytical application of DNA probes, and the use of restriction fragment length polymorphic DNA are described and proposed for increasing use in the future.

  6. Biological doses with template distribution patterns

    SciTech Connect (OSTI)

    Harrop, R. (Simon Fraer Univ., Burnaby, British Columbia); Haymond, H.R.; Nisar, A.; Syed, A.N.M.; Feder, B.H.; Neblett, D.L.

    1981-02-01T23:59:59.000Z

    Consideration of radiation dose rate effects emphasizes advantages of the template method for lateral distribution of multiple sources in treatment of laterally infiltrating gynecologic cancer, when compared to a conventional technique with colpostats. Biological doses in time dose fractionation (TDF), ret and reu units are calculated for the two treatment methods. With the template method the lateral dose (point B) is raised without significantly increasing the doses to the rectum and bladder, that is, relatively, the calculated biological doses at point A and B are more nearly equivalent and the doses to the rectum and bladder are significantly lower than the dose to point B.

  7. Biology and Soft Matter | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials Find Find More LikeAndreasHelp(SC) BiologicalBiology

  8. Systems Modeling for Prognostic Cancer Biology

    E-Print Network [OSTI]

    Maccabe, Barney

    goal of this research is the development of personalized treatments in cancer, based on the genomic and treatment. A major challenge in contemporary cancer diagnosis and treatment is the development Systems Modeling for Prognostic Cancer Biology Xuefei Wang1 , BaiLian Li2 , Cheryl L. Willman

  9. Statistical Applications in Genetics and Molecular Biology

    E-Print Network [OSTI]

    California at Berkeley, University of

    groups of childhood leukemia patients: acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL testing, preprocessing, leukemia, tail probability Merrill D. Birkner is a trainee of the U.C. Berkeley of the Northern California Childhood Leukemia Study, for access to the biological samples. This study

  10. Energy use by biological protein transport pathways

    E-Print Network [OSTI]

    Economou, Tassos

    Energy use by biological protein transport pathways Nathan N. Alder1 and Steven M. Theg2 1 of metabolic energy, using the free energy of ATP and GTP hydrolysis and/or a transmembrane protonmotive force provided insights into the mechanisms of energy transduction, force generation and energy use by different

  11. Biological effectiveness of neutrons: Research needs

    SciTech Connect (OSTI)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01T23:59:59.000Z

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  12. Bioreactor Development for Biological Hydrogen Production

    E-Print Network [OSTI]

    Bioreactor Development for Biological Hydrogen Production Edward J. Wolfrum, Andrew S. Watt, Jie and reactor pressure on the volumetric pro- ductivity of trickle bed bioreactors. The apparent rate constant research focuses on using well- defined bioreactor geometries to collect quantitative reactor performance

  13. Genome Biology 2004, 6:302 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Gent, Universiteit

    Genome Biology 2004, 6, Technologiepark 927, B-9052 Ghent, Belgium. E-mail: Yves.vandepeer@psb.ugent.be Published: 21 December 2004 Genome at http://genomebiology.com/2004/6/1/302 2004 BioMed Central Ltd A report on the Plant Genomics European

  14. Molecular Biology Basics Planning Restriction Enzyme Digests

    E-Print Network [OSTI]

    Aris, John P.

    Molecular Biology Basics Planning Restriction Enzyme Digests A. Checklist: Buffer type Addition of BSA Optimum temperature Number of units of enzyme B. Plan to digest DNA with an "excess" of enzyme activity. Plan for the "excess" to be divided between time of digestion and number of units of enzyme

  15. Apparatus for automated testing of biological specimens

    DOE Patents [OSTI]

    Layne, Scott P. (Los Angeles, CA); Beugelsdijk, Tony J. (Los Alamos, NM)

    1999-01-01T23:59:59.000Z

    An apparatus for performing automated testing of infections biological specimens is disclosed. The apparatus comprise a process controller for translating user commands into test instrument suite commands, and a test instrument suite comprising a means to treat the specimen to manifest an observable result, and a detector for measuring the observable result to generate specimen test results.

  16. VEHICLE USAGE AGREEMENT DEPARTMENT OF BIOLOGICAL SCIENCE

    E-Print Network [OSTI]

    Ronquist, Fredrik

    VEHICLE USAGE AGREEMENT DEPARTMENT OF BIOLOGICAL SCIENCE All drivers of vehicles must certify to the following: 1. I certify that I have a valid driver's license appropriate for the vehicle type and will abide belts. 2. I have read and understand the vehicle operating policies and procedures as defined

  17. Genome Biology 2005, 6:R47 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    and Computational Biology Unit, Laboratory of Genetics National Institute on Aging, National Institutes of Health on media that conveniently allowed reproduction. The advent of digital detectors in microscopy has that linearly measures the flux of light at different points in a cell or tissue. Almost all the vast clinical

  18. Composites comprising biologically-synthesized nanomaterials

    DOE Patents [OSTI]

    Curran, Seamus; Dias, Sampath; Blau, Werner; Wang, Jun; Oremland, Ronald S; Baesman, Shaun

    2013-04-30T23:59:59.000Z

    The present disclosure describes composite materials containing a polymer material and a nanoscale material dispersed in the polymer material. The nanoscale materials may be biologically synthesized, such as tellurium nanorods synthesized by Bacillus selenitireducens. Composite materials of the present disclosure may have optical limiting properties and find use in optical limiting devices.

  19. Institute for Multiscale Modeling of Biological Interactions

    SciTech Connect (OSTI)

    Paulaitis, Michael E; Garcia-Moreno, Bertrand; Lenhoff, Abraham

    2009-12-26T23:59:59.000Z

    The Institute for Multiscale Modeling of Biological Interactions (IMMBI) has two primary goals: Foster interdisciplinary collaborations among faculty and their research laboratories that will lead to novel applications of multiscale simulation and modeling methods in the biological sciences and engineering; and Building on the unique biophysical/biology-based engineering foundations of the participating faculty, train scientists and engineers to apply computational methods that collectively span multiple time and length scales of biological organization. The success of IMMBI will be defined by the following: Size and quality of the applicant pool for pre-doctoral and post-doctoral fellows; Academic performance; Quality of the pre-doctoral and post-doctoral research; Impact of the research broadly and to the DOE (ASCR program) mission; Distinction of the next career step for pre-doctoral and post-doctoral fellows; and Faculty collaborations that result from IMMBI activities. Specific details about accomplishments during the three years of DOE support for IMMBI have been documented in Annual Progress Reports (April 2005, June 2006, and March 2007) and a Report for a National Academy of Sciences Review (October 2005) that were submitted to DOE on the dates indicated. An overview of these accomplishments is provided.

  20. MASTER OF ENGINEERING Biological and Environmental Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    MASTER OF ENGINEERING Biological and Environmental Engineering Program Requirements Fall 2013 The Master of Engineering (MEng) is a professional degree program intended for those who have a Bachelors degree or equivalent in an engineering or closely related science field from a college or university

  1. MASTER OF ENGINEERING Biological and Environmental Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    MASTER OF ENGINEERING Biological and Environmental Engineering Program Requirements Fall 2014 The Master of Engineering (MEng) is a professional degree program intended for those who have a Bachelors degree or equivalent in an engineering or closely related science field from a college or university

  2. Artificial Homeostasis: Integrating Biologically Inspired Computing

    E-Print Network [OSTI]

    Kent, University of

    - mune systems and a novel artificial endocrine system. The natural counterparts of these three of these artificial systems to yield artificially homeostatic systems. The components develop in a common envi. Thus we propose to consider the artificial counterparts of these three biological systems. The use

  3. Brent Craig Christner Department of Biological Sciences

    E-Print Network [OSTI]

    Christner, Brent C.

    , 1996. Thesis advisor: John J. Rowe B.S., Molecular Biology and Biotechnology, Westminster College, New. Assistant Research Professor, August 2004-2006. Department of Land Resources and Environmental Sciences of John C. Priscu, Department of Land Resources and Environmental Sciences, Montana State University

  4. Brent Craig Christner Department of Biological Sciences

    E-Print Network [OSTI]

    Christner, Brent C.

    , Ohio, 1996. Thesis advisor: John J. Rowe B.S., Molecular Biology and Biotechnology, Westminster College Resources and Environmental Sciences, Montana State University, Bozeman, Montana. Postdoctoral Researcher, June 2002-August 2004. Laboratory of John C. Priscu, Department of Land Resources and Environmental

  5. Mentor Program Information Division of Biology

    E-Print Network [OSTI]

    Kaufman, Glennis A.

    Mentor Program Information Division of Biology 116 Ackert Hall Manhattan, KS 66506 Kansas State will never be released for public information unless requested by the mentor. It is used only if a current K-State student requests to speak with a specific mentor and is kept private until that time. However, it may

  6. THE COMPARATIVE VALUE OF BIOLOGICAL CARBON SEQUESTRATION

    E-Print Network [OSTI]

    McCarl, Bruce A.

    THE COMPARATIVE VALUE OF BIOLOGICAL CARBON SEQUESTRATION BRUCE A. MCCARL, BRIAN C. MURRAY, AND UWE A. SCHNEIDER A. Abstract Carbon sequestration via forests and agricultural soils saturates over time to sequestration because of (1) an ecosystems limited ability to take up carbon which we will call saturation

  7. Synthetic biology and the conservation of biodiversity

    E-Print Network [OSTI]

    Redford, Kent H.; Adams, William; Carlson, Rob; Mace, Georgina M.; Ceccarelli, Bertina

    2014-04-22T23:59:59.000Z

    reference to previous debates about land acquisition to grow biofuels, the production 202 of biologically-based chemicals and plastics, and the industrial burning of biomass. 203 Yet not all technologies are the same, nor are the people who use them...

  8. Biological consequences of Chernobyl: 20 years on

    E-Print Network [OSTI]

    Mousseau, Timothy A.

    Biological consequences of Chernobyl: 20 years on Anders Pape Møller1 and Timothy A. Mousseau2 1, University of South Carolina, Columbia, SC 29208, USA The disaster at the Chernobyl nuclear power plant of the four nuclear reactors of the Chernobyl nuclear power plant exploded on 26 April 1986 as a consequence

  9. Genome Biology 2003, 4:R43 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    Kellis, Manolis

    , Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Whitehead/MIT Center for Genome Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Department of Genome conserved word pairs associated with gene-expression changes in yeastsTranscriptional regulation

  10. Methodology in Biological Game Simon M. Huttegger

    E-Print Network [OSTI]

    Zollman, Kevin

    ;Huttegger and Zollman Methodology in Biological Game Theory ESS Method Describe a game Find all the stable states (ESS) If there is only one, conclude this one is evolutionarily significant #12;Huttegger An Evolutionarily Stable Strategy (ESS) Pooling equilibrium Not an ESS Hybrid equilibrium Not an ESS #12;Huttegger

  11. Characterization and Control of Biological Microrobots

    E-Print Network [OSTI]

    magnetic system is five orders-of-magnitude less than the propulsion force gener- ated by the flagellum proposed for propulsion: extracting energy from an ex- ternal magnetic field [4], or extracting energy from of Magnetotactic Bacterium (MTB) which can be considered as a biological microrobot. Magnetic dipole moment

  12. School of Biological Sciences Undergraduate Scholarships & Awards

    E-Print Network [OSTI]

    Barrett, Jeffrey A.

    School of Biological Sciences Undergraduate Scholarships & Awards The following items are due not submit any additional items. 4. Award winners will be notified during the middle of May. 5. To be eligible for any Bio Sci Scholarships/Awards you must be a U.S. citizen, an eligible non

  13. Genome Biology 2007, 8:R34 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    Shneiderman, Ben

    Genome Biology 2007, 8:R34 analytics tool for genome assemblies Michael C Schatz*, Adam M Phillippy*, Ben Shneiderman and Steven L the original work is properly cited. Hawkeye: a visual analytics tool for genome assembliesHawkeye is a new

  14. Simultaneous wastewater treatment and biological electricity generation

    E-Print Network [OSTI]

    Simultaneous wastewater treatment and biological electricity generation B.E. Logan Department accomplishing wastewater treatment in processes based on microbial fuel cell technologies. When bacteria oxidize.4 106 L of wastewater, a wastewater treatment plant has the potential to become a 2.3 MW power plant

  15. Nanotechnology: emerging tools for biology and medicine

    E-Print Network [OSTI]

    Bhatia, Sangeeta

    REVIEW Nanotechnology: emerging tools for biology and medicine Ian Y. Wong,1,2,10 Sangeeta N administration of thera- peutic treatments. Nanotechnology has the potential to transform these paradigms and physical functionality at small length scales. Here, we review nanotechnology- based approaches

  16. GOVERNANCE DOCUMENT DEPARTMENT OF INTEGRATIVE BIOLOGY

    E-Print Network [OSTI]

    Lajeunesse, Marc J.

    1 GOVERNANCE DOCUMENT DEPARTMENT OF INTEGRATIVE BIOLOGY January 23, 2014 The faculty otherwise specified, the following document refers to the IB Department and its personnel only. 1 with the Regular Faculty. The Search Committee will develop a list of candidates, manage the interviews

  17. Deployable structures

    E-Print Network [OSTI]

    Hernndez Merchan, Carlos Henrique

    1987-01-01T23:59:59.000Z

    This thesis has the purpose of describing the meaning and applications of deployable structures (making emphasis in the scissor-hinged and sliding mechanisms.) and the development of new geometries, details, and mechanisms ...

  18. WHAT IS COMPOST? Composting refers to the biological decomposition and stabilization of organic materials by microorganisms under

    E-Print Network [OSTI]

    Mukhtar, Saqib

    , good quality compost is produced that is biologically stable, relatively uniform in appearance, free as 10 to 20 times greater than that from agricultural lands. Research reports from academia, the EPA or topsoil blend to improve soil structure. Both practices help establish a protective vegetation cover

  19. Biologically programmed synthesis of core-shell CdSe/ZnS nanocrystalsw Shailendra Singh,ab

    E-Print Network [OSTI]

    Chen, Wilfred

    not only directs the nucleation of inorganic materials, but also controls the crystal structure and sizeBiologically programmed synthesis of core-shell CdSe/ZnS nanocrystalsw Shailendra Singh report of core-shell semiconductor nanocrystal synthesis using a peptide template. Type II

  20. Protein structure similarity based on multi-view images generated from 3D molecular visualization

    E-Print Network [OSTI]

    Fukui, Kazuhiro

    to protein structure comparison using canonical angles between two subspaces generated from multiple views extension alignment and the Gauss integral tuning. 1. Introduction In structural biology, finding representation of 3D protein structure as a 31- dimensional feature vector called Gauss Integral Tuning (GIT) [6

  1. Biologically Plausible Neural Model for the Recognition of Biological Motion and Actions

    E-Print Network [OSTI]

    Giese, Martin Alexander

    2002-08-01T23:59:59.000Z

    The visual recognition of complex movements and actions is crucial for communication and survival in many species. Remarkable sensitivity and robustness of biological motion perception have been demonstrated in ...

  2. BIOLOGICAL AND MICROBIAL CONTROL Biology and Rearing of Cleruchoides noackae (Hymenoptera

    E-Print Network [OSTI]

    : Mymaridae), an Egg Parasitoid for the Biological Control of Thaumastocoris peregrinus (Hemiptera egg para- sitoid of Thaumastocoris peregrinus Carpintero and Dellape (Hemiptera: Thaumastocoridae peregrinus Carpintero and Dellape (Hemiptera: Thaumastocoridae) is a se- rious and widespread pest

  3. Computational approaches to modeling the conserved structural core among distantly homologous proteins

    E-Print Network [OSTI]

    Menke, Matthew Ewald, 1978-

    2009-01-01T23:59:59.000Z

    Modem techniques in biology have produced sequence data for huge quantities of proteins, and 3-D structural information for a much smaller number of proteins. We introduce several algorithms that make use of the limited ...

  4. Tools for decoding the structure-function relationships of biopolymers in nanotechnology and glycobiology

    E-Print Network [OSTI]

    Soundararajan, Venkataramanan

    2010-01-01T23:59:59.000Z

    In this thesis, new tools have been developed for decoding structure-function relationships governing complex biopolymers that have emerged as key players in biology, biotechnology, and medicine. Specifically: (1.) The ...

  5. Computational Studies of Protein Structure, Dynamics, and Function in Native-like Environments

    E-Print Network [OSTI]

    Rui, Huan

    2013-05-31T23:59:59.000Z

    Proteins are among the four unique organic constituents of cells. They are responsible for a variety of important cell functions ranging from providing structural support to catalyzing biological reactions. They vary in ...

  6. Structure-based drug mechanism study and inhibitor design targeting tuberculosis

    E-Print Network [OSTI]

    Wang, Feng

    2009-05-15T23:59:59.000Z

    The increase of multi-drug resistant and extensively drug resistant tuberculosis (TB) cases makes it urgent to develop a new generation of TB drugs to counter resistance and shorten treatment. Structural biology, which ...

  7. Population structure of the fungal pathogen Holocryphia eucalypti in Australia and South Africa

    E-Print Network [OSTI]

    Population structure of the fungal pathogen Holocryphia eucalypti in Australia and South Africa, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. B Institute, University of Pretoria, Pretoria 0002, South Africa. C School of Biological Sciences

  8. Multifarious Assembly Mixtures: Systems Allowing Retrieval of Diverse Stored Structures

    E-Print Network [OSTI]

    Arvind Murugan; Zorana Zeravcic; Michael P. Brenner; Stanislas Leibler

    2014-08-29T23:59:59.000Z

    Self-assembly materials are traditionally designed so that molecular or meso-scale components form a single kind of large structure. Here, we propose a scheme to create "multifarious assembly mixtures", which self-assemble many different large structures from a set of shared components. We show that the number of multifarious structures stored in the solution of components increases rapidly with the number of different types of components. Yet, each stored structure can be retrieved by tuning only a few parameters, the number of which is only weakly dependent on the size of the assembled structure. Implications for artificial and biological self-assembly are discussed.

  9. Three-dimensionally printed biological machines powered by skeletal muscle

    E-Print Network [OSTI]

    Chan, Vincent

    Combining biological components, such as cells and tissues, with soft robotics can enable the fabrication of biological machines with the ability to sense, process signals, and produce force. An intuitive demonstration of ...

  10. AGRICULTURAL & BIOLOGICAL ENGINEERING FALL 2013 INSIDE THIS ISSUE

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL & BIOLOGICAL ENGINEERING FALL 2013 INSIDE THIS ISSUE: ABESpring of Agricultural and Biological Engineering of the College of Agricultural, Consumer and Environmental Sciences and the College of Engineering at the University of Illinois at Urbana Champaign. 338 Agricultural Engineering

  11. Multispectral optical tweezers for molecular diagnostics of single biological cells

    E-Print Network [OSTI]

    Wu, Shin-Tson

    Multispectral optical tweezers for molecular diagnostics of single biological cells Author, Townes Laser Institute, CREOL The College of Optics and Photonics, Univ. of Central Florida (United States) ABSTRACT Optical trapping of single biological cells has become an established technique

  12. MS.BIOLOGY.NON-THESIS ACADEMIC LEARNING PLAN

    E-Print Network [OSTI]

    O'Laughlin, Jay

    to constructive feedback Job Prospects for Biology Graduates MS/non-thesis in Biology Bioremediation Biotechnology Medical Research Industry Government Education Microbiology Health Professions Research Laboratories Find Food Production Pollution Control Environmental Diagnostics Forestry Agriculture #12;MS

  13. What Was Life? Answers from Three Limit Biologies

    E-Print Network [OSTI]

    Helmreich, Stefan

    2011-01-01T23:59:59.000Z

    What is life? A gathering consensus in anthropology, science studies, and philosophy of biology suggests that the theoretical object of biology, life, is today in transformation, if not dissolution. Proliferating ...

  14. Biochemistry & Molecular Biology Department of Environmental and Biomolecular Systems

    E-Print Network [OSTI]

    Chapman, Michael S.

    Biology _____ _____ _____ EBS 514 Biochemistry III: Metabolism and Bioenergetics Biology _____ _____ _____ EBS 614 Biochemistry III: Metabolism and Bioenergetics _____ _____ _____ Three (3) of the following courses are required: EBS 625 Bioenergetics and Membrane Transport

  15. Project 198740100 Assessment of Smolt Condition: Biological and Environmental Interactions

    E-Print Network [OSTI]

    1 Project 198740100 Assessment of Smolt Condition: Biological and Environmental Interactions detailed investigations of environmental and biological factors that influence smolt development environmental factors influence fish development, condition, and long-term survival. The proposed tasks describe

  16. Extracting principles from biology for application to running robots

    E-Print Network [OSTI]

    Haberland, Matthew Daniel

    2014-01-01T23:59:59.000Z

    When millions of years of evolution suggest a particular design solution, we may be tempted to abandon traditional design methods and copy the biological example. However, biological solutions do not often translate directly ...

  17. The living commons : a spatial theory for biological design

    E-Print Network [OSTI]

    Telhan, Orkan

    2013-01-01T23:59:59.000Z

    Biological design is as ancient as human civilization. For thousands of years, living systems and natural processes have been manipulated by humans and their biological outcomes have been customized for different purposes. ...

  18. Chemistry meets biology in colitis-associated carcinogenesis

    E-Print Network [OSTI]

    Mangerich, Aswin

    The intestine comprises an exceptional venue for a dynamic and complex interplay of numerous chemical and biological processes. Here, multiple chemical and biological systems, including the intestinal tissue itself, its ...

  19. Boston University Physics Colloquium Microscale propulsion in biological and

    E-Print Network [OSTI]

    Mohanty, Raj

    Boston University Physics Colloquium Microscale propulsion in biological and engineered systems biological locomotion and engineered propulsion. In the first example, we examine swimming microorganisms the microstructure. In the second example, we examine engineered magnetic artificial microswimmers which can

  20. Drug Discovery and Development from Marine Biology-Based Research

    E-Print Network [OSTI]

    Jawitz, James W.

    Drug Discovery and Development from Marine Biology- Based Research Oceanyx Pharmaceuticals is a novel drug discovery and development company that leverages marine biology-based natural identified two lead candidates, largazole and apratoxin, as potential drug candidates for the treatment