Sample records for detectable activity mda

  1. 2007-01-3190 Microbial Detection Array (MDA), a Novel Instrument for

    E-Print Network [OSTI]

    Kounaves, Samuel P.

    1 2007-01-3190 Microbial Detection Array (MDA), a Novel Instrument for Unambiguous Detection International ABSTRACT MDA is designed as a test bed for an astrobiology field instrument to detect microbial metabolic activity in terrestrial or extraterrestrial geological soil samples. MDA employs electrochemical

  2. Anti-androgenic activities of environmental pesticides in the MDA-kb2 reporter cell line S. At-Assa *,1

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Anti-androgenic activities of environmental pesticides in the MDA-kb2 reporter cell line S. Aďt for their ability to alter in vitro the transcriptional activity of the androgen receptor in the MDA-kb2 reporter

  3. Towards an MDA-based development methodology for distributed applications

    E-Print Network [OSTI]

    Pires, LuĂ­s Ferreira

    71 Towards an MDA-based development methodology for distributed applications Anastasius Gavras1 and concepts of the Model-Driven Architecture (MDA). The paper identifies phases and activities of an MDA the applicability and potential of MDA in the context of telecom services and applications. This paper also

  4. Towards an MDA-based development methodology1 Anastasius Gavras1

    E-Print Network [OSTI]

    Pires, LuĂ­s Ferreira

    Towards an MDA-based development methodology1 Anastasius Gavras1 , Mariano Belaunde2 , LuĂ­s and concepts of the Model-Driven Architecture (MDA). The paper identifies phases and activities of an MDA the applicability and potential of MDA in the context of telecom services and applications. The paper claims

  5. Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.

    SciTech Connect (OSTI)

    Huang, E. Y.; Madireddi, M. T.; Gopalkrishnan, R. V.; Leszczyniecka, M.; Su, Z. Z.; Lebedeva, I. V.; Kang, D. C.; Jian, H.; Lin, J. J.; Alexandre, D.; Chen, Y.; Vozhilla, N.; Mei, M. X.; Christiansen, K. A.; Sivo, F.; Goldstein, N. I.; Chada, S.; Huberman, E.; Pestka, S.; Fisher, P. B.; Biochip Technology Center; Columbia Univ.; Introgen Therapeutics Inc.; UMDNJ-Robert Wood Johnson Medical School

    2001-10-25T23:59:59.000Z

    Abnormalities in cellular differentiation are frequent occurrences in human cancers. Treatment of human melanoma cells with recombinant fibroblast interferon (IFN-beta) and the protein kinase C activator mezerein (MEZ) results in an irreversible loss in growth potential, suppression of tumorigenic properties and induction of terminal cell differentiation. Subtraction hybridization identified melanoma differentiation associated gene-7 (mda-7), as a gene induced during these physiological changes in human melanoma cells. Ectopic expression of mda-7 by means of a replication defective adenovirus results in growth suppression and induction of apoptosis in a broad spectrum of additional cancers, including melanoma, glioblastoma multiforme, osteosarcoma and carcinomas of the breast, cervix, colon, lung, nasopharynx and prostate. In contrast, no apparent harmful effects occur when mda-7 is expressed in normal epithelial or fibroblast cells. Human clones of mda-7 were isolated and its organization resolved in terms of intron/exon structure and chromosomal localization. Hu-mda-7 encompasses seven exons and six introns and encodes a protein with a predicted size of 23.8 kDa, consisting of 206 amino acids. Hu-mda-7 mRNA is stably expressed in the thymus, spleen and peripheral blood leukocytes. De novo mda-7 mRNA expression is also detected in human melanocytes and expression is inducible in cells of melanocyte/melanoma lineage and in certain normal and cancer cell types following treatment with a combination of IFN-beta plus MEZ. Mda-7 expression is also induced during megakaryocyte differentiation induced in human hematopoietic cells by treatment with TPA (12-O-tetradecanoyl phorbol-13-acetate). In contrast, de novo expression of mda-7 is not detected nor is it inducible by IFN-beta+MEZ in a spectrum of additional normal and cancer cells. No correlation was observed between induction of mda-7 mRNA expression and growth suppression following treatment with IFN-beta+MEZ and induction of endogenous mda-7 mRNA by combination treatment did not result in significant intracellular MDA-7 protein. Radiation hybrid mapping assigned the mda-7 gene to human chromosome 1q, at 1q 32.2 to 1q41, an area containing a cluster of genes associated with the IL-10 family of cytokines. Mda-7 represents a differentiation, growth and apoptosis associated gene with potential utility for the gene-based therapy of diverse human cancers.

  6. Mechanism of MDA5 Recognition of Short RNA Ligands and Crystal Structure of PepQ

    E-Print Network [OSTI]

    Watts, Tylan Aubrey

    2013-05-16T23:59:59.000Z

    differentiationassociated gene 5 (MDA5). Activation of both receptors occurs as a result of binding to RNA. MDA5 only recognizes double stranded forms of RNA, whereas RIG-I is capable of recognizing both single and double stranded RNA. In vivo, MDA5 is known...

  7. Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

    E-Print Network [OSTI]

    Strong, Roland K.

    Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5 Xiaojun Li online 14 June 2009 Keywords: Innate immunity Nucleic acid receptor MDA5 CTD Crystal structure a b s t r a c t RIG-I, MDA5 and LGP2 are cytosolic pattern recognition receptors detecting single

  8. UV Decontamination of MDA Reagents for Single Cell Genomics

    E-Print Network [OSTI]

    Lee, Janey

    2011-01-01T23:59:59.000Z

    UV Decontamination of MDA Reagents for Single Cell GenomicsUV Decontamination of MDA Reagents for Single Cell Genomicsdisplacement amplification (MDA), which can generate

  9. UV Decontamination of MDA Reagents for Single Cell Genomics

    E-Print Network [OSTI]

    Lee, Janey

    2011-01-01T23:59:59.000Z

    UV Decontamination of MDA Reagents for Single Cell Genomicsof California. UV Decontamination of MDA Reagents for Singleand highly efficient decontamination method of MDA reagents

  10. Theorem 13 (MDA(), alternative Charakterisierung) Eine Verteilungsfunktion F gehort zu MDA() dann und nur dann

    E-Print Network [OSTI]

    Dragoti-Ă?ela, Eranda

    Theorem 13 (MDA(), alternative Charakterisierung) Eine Verteilungsfunktion F geh¨ort zu MDA() dann Verteilungen, die dem MDA() geh¨oren: · Normal: F(x) = (2)-1/2 exp{-x2/2}, x IR. · Exponential: f(x) = -1 exp¨ur MDA(H)) Sein IR. Die untenstehenden Aussagen sind

  11. Theorem 13 (MDA(), alternative Charakterisierung) Eine Verteilungsfunktion F gehort zu MDA() dann und nur dann

    E-Print Network [OSTI]

    Dragoti-Ă?ela, Eranda

    Theorem 13 (MDA(), alternative Charakterisierung) Eine Verteilungsfunktion F geh¨ort zu MDA() dann Verteilungen, die dem MDA() geh¨oren: · Normal: F(x) = (2)-1/2 exp{-x2/2}, x IR. · Exponential: f(x) = -1 exp MDA(H)) Sein IR. Die untenstehenden Aussagen sind ¨aquivalent: (i) F MDA(H) (ii) Es existiert eine

  12. Migrating a Domain-Specific Modeling Infrastructure to MDA Technology

    E-Print Network [OSTI]

    van Deursen, Arie

    Migrating a Domain-Specific Modeling Infrastructure to MDA Technology Duncan Doyle1,2, Hans Geers2 be migrated to models conform the MDA, in order to benefit from the range of MDA standards. We describe of the lessons learned. 1 Introduction The MDA promise of model-driven development is becoming a reality

  13. Digital MDA for enumeration of total nucleic acid contamination

    E-Print Network [OSTI]

    Quake, Stephen R.

    Digital MDA for enumeration of total nucleic acid contamination Paul C. Blainey and Stephen R; Accepted October 14, 2010 ABSTRACT Multiple displacement amplification (MDA) is an iso- thermal, sequence). Here we report digital MDA (dMDA), an ultrasensitive method for quantifying nucleic acid fragments

  14. INDEPENDENT RESEARCH IN NARRATIVE STUDIES (MDA 490/494)

    E-Print Network [OSTI]

    Rohs, Remo

    CAPSTONE INDEPENDENT RESEARCH IN NARRATIVE STUDIES (MDA 490/494) MDA 490/494 is an independent in Narrative Studies. Most often your study will result in a substantial research paper (MDA 490). Occasionally it will result in a creative project (MDA 494). The terms of your independent study are negotiated at the outset

  15. Components, Platforms and Possibilities: Towards Generic Automation for MDA

    E-Print Network [OSTI]

    Jackson, Daniel

    Components, Platforms and Possibilities: Towards Generic Automation for MDA Ethan K. Jackson Model-driven architecture (MDA) is a model-based approach for engineering complex software systems. MDA and software re- quirements evolve. However, efforts to apply MDA in in- dustrial settings expose several open

  16. Calling a Spade a Spade in the MDA Infrastructure

    E-Print Network [OSTI]

    KĂĽhne, Thomas

    Calling a Spade a Spade in the MDA Infrastructure Colin Atkinson University of Mannheim 68161 to play in the realization of the MDA. It is therefore essential that the MDA community establish a clear of metamodeling in the MDA approach is generally looked at from one angle only. The "accepted wisdom

  17. The Role of Metamodeling in MDA Colin Atkinson

    E-Print Network [OSTI]

    KĂĽhne, Thomas

    1 The Role of Metamodeling in MDA Colin Atkinson colin.atkinson@ieee.org Thomas KĂĽhne Darmstadt of the MDA, but less consensus on what the precise role of metamodeling should be and what form it should of the MDA and derive a concrete set of requirements that an MDA supporting infrastructure should satisfy. We

  18. An MDA approach to tame component based software development

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    FMCO'03 An MDA approach to tame component based software development Jean-Marc Jézéquel, Olivier- ture (MDA) can be used in relation with component based software engineer- ing. A software component

  19. Harvesting Software Systems for MDA-Based Reengineering

    E-Print Network [OSTI]

    van Deursen, Arie

    Harvesting Software Systems for MDA-Based Reengineering Thijs Reus1 , Hans Geers2 , and Arie van- ing legacy systems towards a model-driven architecture (MDA). Steps in our approach consist of (1 tool that is based on Arc- Styler, the MDA environment provided by Interactive Objects. Our pa- per

  20. Models simulation and interoperability using MDA and HLA

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Models simulation and interoperability using MDA and HLA Hind El Haouzi CRAN (UMR 7039), University manufacturing environments. Our paper advocates for an approach combining MDA (model driven architecture interopérabilité dans le contexte de la simulation distribuée. Nos travaux visent ŕ combiner les architectures MDA

  1. Platform-independent modelling in MDA: supporting abstract platforms

    E-Print Network [OSTI]

    Pires, LuĂ­s Ferreira

    Platform-independent modelling in MDA: supporting abstract platforms JoĂŁo Paulo Almeida, Remco { almeida, dijkman, sinderen, pires } @ cs.utwente.nl Abstract. An MDA-based design approach should be able as the various design goals. In this paper, we discuss how our design approach can be supported using the MDA

  2. Detecting Bots Based on Keylogging Activities

    E-Print Network [OSTI]

    Al-Hammadi, Yousof

    2010-01-01T23:59:59.000Z

    A bot is a piece of software that is usually installed on an infected machine without the user's knowledge. A bot is controlled remotely by the attacker under a Command and Control structure. Recent statistics show that bots represent one of the fastest growing threats to our network by performing malicious activities such as email spamming or keylogging. However, few bot detection techniques have been developed to date. In this paper, we investigate a behavioural algorithm to detect a single bot that uses keylogging activity. Our approach involves the use of function calls analysis for the detection of the bot with a keylogging component. Correlation of the frequency of a specified time-window is performed to enhance he detection scheme. We perform a range of experiments with the spybot. Our results show that there is a high correlation between some function calls executed by this bot which indicates abnormal activity in our system.

  3. Human Activity Detection from RGBD Images

    E-Print Network [OSTI]

    Sung, Jaeyong; Selman, Bart; Saxena, Ashutosh

    2011-01-01T23:59:59.000Z

    Being able to detect and recognize human activities is important for making personal assistant robots useful in performing assistive tasks. The challenge is to develop a system that is low-cost, reliable in unstructured home settings, and also straightforward to use. In this paper, we use a RGBD sensor (Microsoft Kinect) as the input sensor, and present learning algorithms to infer the activities. Our algorithm is based on a hierarchical maximum entropy Markov model (MEMM). It considers a person's activity as composed of a set of sub-activities, and infers the two-layered graph structure using a dynamic programming approach. We test our algorithm on detecting and recognizing twelve different activities performed by four people in different environments, such as a kitchen, a living room, an office, etc., and achieve an average performance of 84.3% when the person was seen before in the training set (and 64.2% when the person was not seen before).

  4. Radiation Detection for Active Interrogation of HEU

    SciTech Connect (OSTI)

    Mihalczo, J.T.

    2004-12-09T23:59:59.000Z

    This report briefly describes the neutrons and gamma rays emitted by active interrogation of HEU, briefly discusses measurement methods, briefly discusses sources and detectors relevant to detection of shielded HEU in Sealand containers, and lists the measurement possibilities for the various sources. All but one of the measurement methods detect radiation emitted by induced fission in the HEU; the exception utilizes nuclear resonance fluorescence. The brief descriptions are supplemented by references. This report presents some active interrogation possibilities but the status of understanding is not advanced enough to select particular methods. Additional research is needed to evaluate these possibilities.

  5. Analyte detection using an active assay

    DOE Patents [OSTI]

    Morozov, Victor (Manassas, VA); Bailey, Charles L. (Cross Junction, VA); Evanskey, Melissa R. (Potomac Falls, VA)

    2010-11-02T23:59:59.000Z

    Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membrane may be semi-permeable to nonanalytes. The layer of polymers may include cross-linked polymers. A plurality of probe molecules may be arrayed and immobilized on the lacquered membrane. An external force may be applied to the analyte solution to move the analytes towards the lacquered membrane. Movement may cause some or all of the analytes to bind to the lacquered membrane. In cases where probe molecules are presented, some or all of the analytes may bind to probe molecules. The direction of the external force may be reversed to remove unbound or weakly bound analytes. Bound analytes may be detected using known detection types.

  6. REAL-TIME ACTIVE PIPELINE INTEGRITY DETECTION (RAPID) SYSTEM FOR CORROSION DETECTION AND QUANTIFICATION

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    alone there are over 2 million miles of natural gas transmission and distribution pipeline providing 24REAL-TIME ACTIVE PIPELINE INTEGRITY DETECTION (RAPID) SYSTEM FOR CORROSION DETECTION detection Acellent has developed a Real-time Active Pipeline Integrity Detection (RAPID) system. The RAPID

  7. Model Transformations for the MDA with Frank Marschall and Peter Braun

    E-Print Network [OSTI]

    Model Transformations for the MDA with BOTL Frank Marschall and Peter Braun Institut f Architecture (MDA) approach and for a model transformation language that is used to specify, Model Transformation, Metamodel, Refinement, UML 1 Introduction The MDA (Soley, 2000; OMG-MDA, 2001

  8. Handling QoS in MDA: a discussion on availability and dynamic reconfiguration

    E-Print Network [OSTI]

    van Sinderen, Marten

    Handling QoS in MDA: a discussion on availability and dynamic reconfiguration 1 JoĂŁo Paulo Almeidaa-Driven Architecture (MDA) approach. In order to illustrate our discussion, we consider the introduction-Driven Architecture (MDA) approach [9]. The concept of platform-independence plays a central role in MDA development

  9. Active carbon filter health condition detection with piezoelectric wafer active sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Active carbon filter health condition detection with piezoelectric wafer active sensors Jingjing Chemical Biological Center, 5183 Blackhawk Road, APG, MD USA 21010 ABSTRACT The impregnated active carbon in active carbon filters by combining the electromechanical impedance spectroscopy (EMIS

  10. active fault detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    with wireless communications are the bedrock of an emerging are manifold from diet monitor- ing 18, activity detection 4, 3, and health crisis support 9. We focus...

  11. active fire detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in North America from long-term records of the advanced very high resolution radiometer Geosciences Websites Summary: Interannual changes of active fire detectability in...

  12. Detecting Termination of Active Database Rules Using Symbolic Model Checking

    E-Print Network [OSTI]

    Ray, Indrakshi

    Detecting Termination of Active Database Rules Using Symbolic Model Checking Indrakshi Ray is the non-termination of rules. Although algorithms have been proposed to detect non-termination, al- most all provide a conservative estimate; that is, the algorithms detect all the potential cases of non-termination

  13. Active duplicate detection with Bayesian nonparametric models

    E-Print Network [OSTI]

    Matsakis, Nicholas E. (Nicholas Elias), 1976-

    2010-01-01T23:59:59.000Z

    When multiple databases are merged, an essential step is identifying sets of records that refer to the same entity. Called duplicate detection, this task is typically tedious to perform manually, and so a variety of automated ...

  14. Molecular Mechanisms of Paclitaxel Resistance and Resveratrol Sensitivity in MDA-MB-231 Breast Cancer Cells

    E-Print Network [OSTI]

    Zhou, Yaoqi

    Molecular Mechanisms of Paclitaxel Resistance and Resveratrol Sensitivity in MDA-MB-231 Breast was generated from the breast cancer cell line MDA-MB-231. A "spiking" method of paclitaxel treatment was used

  15. Incorporating Agile with MDA Case Study: Online Polling System

    E-Print Network [OSTI]

    Guha, Pritha; Shukla, Shiv Shankar Prasad; Singh, Shweta; 10.5121/ijsea.2011.2408

    2011-01-01T23:59:59.000Z

    Nowadays agile software development is used in greater extend but for small organizations only, whereas MDA is suitable for large organizations but yet not standardized. In this paper the pros and cons of Model Driven Architecture (MDA) and Extreme programming have been discussed. As both of them have some limitations and cannot be used in both large scale and small scale organizations a new architecture has been proposed. In this model it is tried to opt the advantages and important values to overcome the limitations of both the software development procedures. In support to the proposed architecture the implementation of it on Online Polling System has been discussed and all the phases of software development have been explained.

  16. Nearest-Neighbor-Based Active Learning for Rare Category Detection

    E-Print Network [OSTI]

    Carbonell, Jaime

    Mellon University jgc@cs.cmu.edu Abstract Rare category detection is an open challenge for active for data mining - e.g. detecting new financial transaction fraud patterns, where normal legitimate to stopping similar future fraud transactions [2]. Another example is in astronomy. Most of the objects in sky

  17. An active oil spill detection digital processing system 

    E-Print Network [OSTI]

    Dennard, Robert Marion

    1976-01-01T23:59:59.000Z

    AN ACTIVE OIL SPILL DETECTION DIGITAL PROCESSING SYSTEM A Thesis by Robert Marion Dennard Submitted to the Graduate College of Texas A/M University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE December 1976... Major Subject: Electrical Engineering AN ACTIVE OIL SPILL DETECTION DIGITAL PROCESSING SYSTEM A Thesis by Robert Marion Dennard Approved as to style and content by: Chairman o Committee Hea o epart ent M er em er December 1976 ABSTRACT...

  18. SNM detection by active muon interrogation

    SciTech Connect (OSTI)

    Jason, Andrew J [Los Alamos National Laboratory; Miyadera, Haruo [Los Alamos National Laboratory; Turchi, Peter J [Los Alamos National Laboratory

    2010-01-01T23:59:59.000Z

    Muons are charged particles with mass between the electron and proton and can be produced indirectly through pion decay by interaction of a charged-particle beam with a target. There are several distinct features of the muon interaction with matter attractive as a probe for detection of SNM at moderate ranges. These include muon penetration of virtually any amount of material without significant nuclear interaction until stopped by ionization loss in a short distance. When stopped, high-energy penetrating x-rays (in the range of 6 MeV for uranium,) unique to isotopic composition are emitted in the capture process. The subsequent interaction with the nucleus produces additional radiation useful in assessing SNM presence. A focused muon beam can be transported through the atmosphere, at a range limited mainly by beam-size growth through scattering. A muonbeam intensity of > 10{sup 9} /second is required for efficient interrogation and, as in any other technique, dose limits are to be respected. To produce sufficient muons a high-energy (threshold {approx}140 MeV) high-intensity (<1 mA) proton or electron beam is needed implying the use of a linear accelerator to bombard a refractory target. The muon yield is fractionally small, with large angle and energy dispersion, so that efficient collection is necessary in all dimensions of phase space. To accomplish this Los Alamos has proposed a magnetic collection system followed by a unique linear accelerator that provides the requisite phase-space bunching and allows an energy sweep to successively stop muons throughout a large structure such as a sea-going vessel. A possible maritime application would entail fitting the high-gradient accelerators on a large ship with a helicopter-borne detection system. We will describe our experimental results for muon effects and particle collection along with our current design and program for a muon detection system.

  19. MDA Employed in a Joint eGovernment Strategy: An Experience Report

    E-Print Network [OSTI]

    Gogolla, Martin - Fachbereich 3

    MDA Employed in a Joint eGovernment Strategy: An Experience Report Fabian BË? uttner 1 , Mirco creation of data exchange specifications from these platform­ specific models is realised by an MDA tool OCL constraints, and the XGenerator supports a flexible, MDA based generation of XML Schema

  20. Requirements Capture and Specification for Enterprise Applications: an MDA compliant attempt

    E-Print Network [OSTI]

    Choppy, Christine

    Requirements Capture and Specification for Enterprise Applications: an MDA compliant attempt, and the use of the UML notation, within an MDA approach. Problem frames are patterns that provide a precise the involved domains, the requirements, the design, and their interfaces. Being within an overall MDA approach

  1. Applying MDA to the Development of Data Warehouses Jose-Norberto Mazn, Juan Trujillo

    E-Print Network [OSTI]

    Song, Il-Yeol

    Applying MDA to the Development of Data Warehouses Jose-Norberto MazĂłn, Juan Trujillo Dept Architecture (MDA) is a standard framework for software development that addresses the complete life cycle. In this paper, we describe how to align the whole DW development process to MDA. Then, we define MD2 A (Multi

  2. September 17, 2010 LSUHSC named first MDA/ALS Clinic in LA

    E-Print Network [OSTI]

    September 17, 2010 LSUHSC named first MDA/ALS Clinic in LA LSUHSC's Camp Tiger theme - Calling All to care regardless of their economic background. LSUHSC is the 44th MDA/ALS center in the country, joining a national network of MDA/ALS centers that provide a multidisciplinary team of medical professionals skilled

  3. Evolution of MDA-5/RIG-I-dependent innate immunity: Independent evolution by domain grafting

    E-Print Network [OSTI]

    DeSalle, Rob

    Evolution of MDA-5/RIG-I-dependent innate immunity: Independent evolution by domain grafting interferons. However, recent recognition of melanoma differentiation associated gene-5 (MDA-5) and retinoic- genetic origin of MDA-5 and RIG-I domain arrangement (CARD1- CARD2-helicase-DEAD/DEAH) indicates

  4. Evaluating the Use of AOP and MDA in Web Service Development

    E-Print Network [OSTI]

    Bordbar, Behzad

    Evaluating the Use of AOP and MDA in Web Service Development Guadalupe Ortiz Quercus Software-- Model-Driven Architecture (MDA) is introduced to shorten the software development time, produce better. As a result, it can be argued that adopting AOP and MDA side- by-side will provide advantages from both sets

  5. The role of the RM-ODP Computational Viewpoint Concepts in the MDA approach

    E-Print Network [OSTI]

    Pires, LuĂ­s Ferreira

    43 The role of the RM-ODP Computational Viewpoint Concepts in the MDA approach JoĂŁo Paulo A.utwente.nl Abstract An MDA design approach should be able to accommodate designs at different levels of platform that makes it possible to use RM-ODP concepts in our MDA design approach. This framework allows a recursive

  6. MDA-based Approach for Embedded Software Generation from a UML/MOF Repository

    E-Print Network [OSTI]

    Wagner, Flávio Rech

    MDA-based Approach for Embedded Software Generation from a UML/MOF Repository 1 Francisco A. M. do, following the MDA approach, which is oriented to the design space exploration of embedded systems, based, Languages Keywords Embedded systems design, Design space exploration, UML, MDA. 1. INTRODUCTION Approaches

  7. Tools for MDA Software Development: Evaluation Criteria and Set of Desirable Features

    E-Print Network [OSTI]

    Dascalu, Sergiu

    Tools for MDA Software Development: Evaluation Criteria and Set of Desirable Features Tihomir Calic}@cse.unr.edu Abstract Model Driven Architecture (MDA) is a new approach to software development that moves standard code(s) and fully executable source code. MDA provides interoperability capabilities between different technologies

  8. MDA and Analysis of Web Applications Behzad Bordbar and Kyriakos Anastasakis

    E-Print Network [OSTI]

    Bordbar, Behzad

    MDA and Analysis of Web Applications Behzad Bordbar and Kyriakos Anastasakis School of Computer on Petri nets. Our approach makes use of MDA [5­7] transformations to automatically create the analysable of the interaction between browsers and the business logic. Figure 1 sketches our approach. The MDA [5­7] emphasises

  9. Approche MDA pour la transformation d'un modle UML en un schma relationnel

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Approche MDA pour la transformation d'un modčle UML en un schéma relationnel Utilisation de la, conception de base de données, normalisation, MDA, UML, CWM. KEYWORDS: Model transformation, database design, normalization, MDA, UML, CWM. hal-00450857,version1-27Jan2010 Manuscrit auteur, publié dans "INFORSID 2007

  10. Middleware Transparent Software Development & the MDA Devon Simmonds, Sudipto Ghosh, Robert France

    E-Print Network [OSTI]

    Simmonds, Devon M.

    Middleware Transparent Software Development & the MDA Devon Simmonds, Sudipto Ghosh, Robert France of middleware technologies and the pervasiveness of distributed systems. The Model Driven Architecture (MDA of the target middleware. To support the MDA vision we have developed an aspect-oriented middleware transparent

  11. Applying UML and MDA to Real Systems Design Nokia Research Center, Finland

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Applying UML and MDA to Real Systems Design Ian Oliver Nokia Research Center, Finland ian.oliver@nokia.com 1 UML and MDA Traditionally system design has been made from a black box/functionality only such as the OMG's Model Based Architecture (MDA) or Model Based Engineering (MBE)1 and the ubiq- uitous modelling

  12. Applying UML and MDA to Real Systems Design

    E-Print Network [OSTI]

    Oliver, Ian

    2011-01-01T23:59:59.000Z

    Traditionally system design has been made from a black box/functionality only perspective which forces the developer to concentrate on how the functionality can be decomposed and recomposed into so called components. While this technique is well established and well known it does suffer fromsome drawbacks; namely that the systems produced can often be forced into certain, incompatible architectures, difficult to maintain or reuse and the code itself difficult to debug. Now that ideas such as the OMG's Model Based Architecture (MDA) or Model Based Engineering (MBE) and the ubiquitous modelling language UML are being used (allegedly) and desired we face a number of challenges to existing techniques.

  13. Prototyping an Infrastructure for MDA Submitted in partial fulfillment of the requirements for the degree Master of

    E-Print Network [OSTI]

    Moeller, Ralf

    Prototyping an Infrastructure for MDA Kai Yuan Submitted in partial fulfillment of the requirements Systems Institute (STS) #12;1 Abstract Model Driven Architecture (MDA) is getting popular with its be applied as MDA transformation engine to build an Octopus based MDA infrastructure. This thesis explains

  14. Cellular/Molecular Detecting Activity in Olfactory Bulb Glomeruli with

    E-Print Network [OSTI]

    Newman, Eric A.

    Cellular/Molecular Detecting Activity in Olfactory Bulb Glomeruli with Astrocyte Recording Didier, Oregon 97239 In the olfactory bulb, axons of olfactory sensory neurons (OSNs) expressing the same to examine functional compartmentalization within and between olfactory bulb glomeruli. Key words: olfactory

  15. Un estudio comparativo de dos herramientas MDA: OptimalJ y ArcStyler

    E-Print Network [OSTI]

    Ortín, María José

    Un estudio comparativo de dos herramientas MDA: OptimalJ y ArcStyler J. García Molina, J. Rodríguez MDA. En esta ponencia presentamos los resultados de un trabajo que ha consistido en realizar una comparación de las dos herramientas MDA más extendidas: OptimalJ y ArcStyler. Primero evaluamos cada una de

  16. MDA based-approach for UML Models Complete Comparison

    E-Print Network [OSTI]

    Chaouni, Samia Benabdellah; Mouline, Salma

    2011-01-01T23:59:59.000Z

    If a modeling task is distributed, it will frequently be necessary to integrate models developed by different team members. Problems occur in the models integration step and particularly, in the comparison phase of the integration. This issue had been discussed in several domains and various models. However, previous approaches have not correctly handled the semantic comparison. In the current paper, we provide a MDA-based approach for models comparison which aims at comparing UML models. We develop an hybrid approach which takes into account syntactic, semantic and structural comparison aspects. For this purpose, we use the domain ontology as well as other resources such as dictionaries. We propose a decision support system which permits the user to validate (or not) correspondences extracted in the comparison phase. For implementation, we propose an extension of the generic correspondence metamodel AMW in order to transform UML models to the correspondence model.

  17. Mechanical Ventilation Jairo I. Santanilla, MDa,b,*, Brian Daniel, RRTc

    E-Print Network [OSTI]

    Mechanical Ventilation Jairo I. Santanilla, MDa,b,*, Brian Daniel, RRTc , Mei-Ean Yeow, MDa leads to a delay in transfer and ventilator management falls upon the emergency medicine (EM) physician to troubleshoot or stabilize mechanically ventilated patients in the ICU. This article reviews the common modes

  18. ARQUITECTURAS DE SISTEMAS DE INFORMAO E A INICIATIVA MDA MARCO COSTA*

    E-Print Network [OSTI]

    da Silva, Alberto Rodrigues

    ARQUITECTURAS DE SISTEMAS DE INFORMA��O E A INICIATIVA MDA MARCO COSTA* e ALBERTO RODRIGUES DA Management Group MDA approach and two concrete initiatives, Codagen and XIS. RESUMO A Arquitectura de comparação e discussão entre diversas abordagens existentes para a formalização de arquitecturas de sistemas

  19. Enhanced ULF electromagnetic activity detected by DEMETER above seismogenic regions

    E-Print Network [OSTI]

    Athanasiou, M; David, C; Anagnostopoulos, G

    2013-01-01T23:59:59.000Z

    In this paper we present results of a comparison between ultra low frequency (ULF) electromagnetic (EM) radiation, recorded by an electric field instrument (ICE) onboard the satellite DEMETER in the topside ionosphere, and the seismicity of regions with high and lower seiismic activity. In particular we evaluated the energy variations of the ULF Ez-electric field component during a period of four years (2006-2009), in order to examine check the possible relation of ULF EM radiation with seismogenic regions located in central America, Indonesia, Eastern Mediterranean Basin and Greece. As a tool of evaluating the ULF Ez energy variations we used Singular Spectrum Analysis (SSA) techniques. The results of our analysis clearly show a significant increase of the ULF EM energy emmited from regions of highest seismic activity at the tectonic plates boundaries. We interpret these results as suggesting that the highest ULF EM energy detected in the topside ionosphere is originated from seismic processes within Earth's...

  20. Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells

    E-Print Network [OSTI]

    Kenny, Paraic

    Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 of MCU expression in the basal-like MDA-MB-231 breast cancer cell line produced no change

  1. Associate editor: S. Pestka Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of

    E-Print Network [OSTI]

    DeSalle, Rob

    Associate editor: S. Pestka Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key York, NY, USA a b s t r a c ta r t i c l e i n f o Keywords: Antiviral innate immunity MDA-5 RIG been identified, which comprises the cytoplasmic sensors of viral nucleic acids, including MDA-5, RIG

  2. On the Notion of Abstract Platform in MDA Development Joo Paulo Almeida, Remco Dijkman, Marten van Sinderen, Lus Ferreira Pires

    E-Print Network [OSTI]

    van Sinderen, Marten

    On the Notion of Abstract Platform in MDA Development JoĂŁo Paulo Almeida, Remco Dijkman, Marten van Although platform-independence is a central property in MDA models, the study of platform- independence has been largely overlooked in MDA. As a consequence, there is a lack of guidelines to select abstraction

  3. Modulation of the HGF/c-Met/Akt and p38 cell signaling pathways by 3,3'-diindolylmethane in MDA-MB-231 breast cancer cells

    E-Print Network [OSTI]

    Nicastro, Holly

    2010-01-01T23:59:59.000Z

    A) Confluent monolayers of MDA- MB-231 cells were scratchedMCF-7 and ER-negative MDA-MB-231 breast cancer cells. Cancerand metastatic potential of MDA-MB-231 breast cancer cells

  4. Maximum entropy detection of planets around active stars

    E-Print Network [OSTI]

    Petit, P; Hébrard, E; Morin, J; Folsom, C P; Böhm, T; Boisse, I; Borgniet, S; Bouvier, J; Delfosse, X; Hussain, G; Jeffers, S V; Marsden, S C; Barnes, J R

    2015-01-01T23:59:59.000Z

    (shortened for arXiv) We aim to progress towards more efficient exoplanet detection around active stars by optimizing the use of Doppler Imaging in radial velocity measurements. We propose a simple method to simultaneously extract a brightness map and a set of orbital parameters through a tomographic inversion technique derived from classical Doppler mapping. Based on the maximum entropy principle, the underlying idea is to determine the set of orbital parameters that minimizes the information content of the resulting Doppler map. We carry out a set of numerical simulations to perform a preliminary assessment of the robustness of our method, using an actual Doppler map of the very active star HR 1099 to produce a realistic synthetic data set for various sets of orbital parameters of a single planet in a circular orbit. Using a simulated time-series of 50 line profiles affected by a peak-to-peak activity jitter of 2.5 km/s, we are able in most cases to recover the radial velocity amplitude, orbital phase and o...

  5. Models and Technologies Activation of Peroxisome Proliferator-Activated Receptor-

    E-Print Network [OSTI]

    Omiecinski, Curtis

    of PPAR-b/d caused a decrease in cell proliferation in MCF7 and MDA-MB-231 cells compared with controls, whereas ligand activation of PPAR-b/d further inhibited proliferation of MCF7 but not MDA-MB-231 cells. Overexpression and/or ligand activation of PPAR-b/d in MDA-MB-231 or MCF7 cells had no effect on experimental

  6. Detecting Bots Based on Keylogging Activities Yousof Al-Hammadi and Uwe Aickelin

    E-Print Network [OSTI]

    Aickelin, Uwe

    Detecting Bots Based on Keylogging Activities Yousof Al-Hammadi and Uwe Aickelin Department network by performing malicious activities such as email spamming or keylogging. However, few bot to detect a single bot that uses keylogging activity. Our approach involves the use of function calls

  7. WANG et al.: CLASSIFICATION BASED MDA PREDICTION FOR SCALABLE VIDEO CODING USING SUBJECTIVE QUALITY 1 Abstract -Scalable video coding offers a flexible representation

    E-Print Network [OSTI]

    Chang, Shih-Fu

    WANG et al.: CLASSIFICATION BASED MDA PREDICTION FOR SCALABLE VIDEO CODING USING SUBJECTIVE QUALITY-dimensional adaptation (MDA) problem in an ad hoc manner. One challenging issue affecting the systematic MDA solution video utility and MDA operations. In this paper, we propose a general classification-based prediction

  8. active snm detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    learning algorithms to infer the activities. Our algorithm is based on a hierarchical maximum entropy Markov model (MEMM). It considers a persons activity as composed of a...

  9. activity detection based: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    learning algorithms to infer the activities. Our algorithm is based on a hierarchical maximum entropy Markov model (MEMM). It considers a persons activity as composed of a...

  10. active case detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    learning algorithms to infer the activities. Our algorithm is based on a hierarchical maximum entropy Markov model (MEMM). It considers a persons activity as composed of a...

  11. Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces

    DOE Patents [OSTI]

    Salafsky, Joshua S.; Eisenthal, Kenneth B.

    2005-10-11T23:59:59.000Z

    This invention provides methods of detecting molecules at an interface, which comprise labeling the molecules with a second harmonic-active moiety and detecting the labeled molecules at the interface using a surface selective technique. The invention also provides methods for detecting a molecule in a medium and for determining the orientation of a molecular species within a planar surface using a second harmonic-active moiety and a surface selective technique.

  12. active neutron detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the device ("skyshine"). Taylor, David; Turner, Andrew; Davis, Andrew 2014-01-01 48 An aerogel Cherenkov detector for multi-GeV photon detection with low sensitivity to neutrons...

  13. A Multidisciplinary Approach To Detect Active Pathways For Magma...

    Open Energy Info (EERE)

    the upper southern flank of the volcano, a particularly active area during the last 30 years, damaging several tourist facilities and threatening some villages. The composite...

  14. Active remote detection of radioactivity based on electromagnetic signatures

    SciTech Connect (OSTI)

    Sprangle, P. [Plasma Physics Division, Naval Research Laboratory, Washington, District of Columbia 20375 (United States) [Plasma Physics Division, Naval Research Laboratory, Washington, District of Columbia 20375 (United States); University of Maryland, College Park, Maryland 20742-4111 (United States); Hafizi, B. [Plasma Physics Division, Naval Research Laboratory, Washington, District of Columbia 20375 (United States)] [Plasma Physics Division, Naval Research Laboratory, Washington, District of Columbia 20375 (United States); Milchberg, H.; Nusinovich, G. [University of Maryland, College Park, Maryland 20742-4111 (United States)] [University of Maryland, College Park, Maryland 20742-4111 (United States); Zigler, A. [University of Maryland, College Park, Maryland 20742-4111 (United States) [University of Maryland, College Park, Maryland 20742-4111 (United States); Icarus Research, Inc., PO Box 30780, Bethesda, Maryland 20824-0780 (United States); The Hebrew University of Jerusalem, Jerusalem (Israel)

    2014-01-15T23:59:59.000Z

    This paper presents a new concept for the remote detection of radioactive materials. The concept is based on the detection of electromagnetic signatures in the vicinity of radioactive material and can enable stand-off detection at distances greater than 100?m. Radioactive materials emit gamma rays, which ionize the surrounding air. The ionized electrons rapidly attach to oxygen molecules forming O{sub 2}{sup ?} ions. The density of O{sub 2}{sup ?} around radioactive material can be several orders of magnitude greater than background levels. The elevated population of O{sub 2}{sup ?} extends several meters around the radioactive material. Electrons are easily photo-detached from O{sub 2}{sup ?} ions by laser radiation. The photo-detached electrons, in the presence of laser radiation, initiate avalanche ionization which results in a rapid increase in electron density. The rise in electron density induces a frequency modulation on a probe beam, which becomes a direct spectral signature for the presence of radioactive material.

  15. Recognizing Threat: A Simple Geometric Shape Activates Neural Circuitry for Threat Detection

    E-Print Network [OSTI]

    Sarinopoulos, Issidoros

    Recognizing Threat: A Simple Geometric Shape Activates Neural Circuitry for Threat Detection the perception of threat. We here re- port that the neural circuitry known to be mobilized by many realistic instantiating detection of threat and negative affect, suggesting that recognition of potential danger may

  16. Rapid Detection of Biological and Chemical Threat Agents Using Physical Chemistry, Active Detection, and Computational Analysis

    SciTech Connect (OSTI)

    Chung, Myung; Dong, Li; Fu, Rong; Liotta, Lance; Narayanan, Aarthi; Petricoin, Emanuel; Ross, Mark; Russo, Paul; Zhou, Weidong; Luchini, Alessandra; Manes, Nathan; Chertow, Jessica; Han, Suhua; Kidd, Jessica; Senina, Svetlana; Groves, Stephanie

    2007-01-01T23:59:59.000Z

    Basic technologies have been successfully developed within this project: rapid collection of aerosols and a rapid ultra-sensitive immunoassay technique. Water-soluble, humidity-resistant polyacrylamide nano-filters were shown to (1) capture aerosol particles as small as 20 nm, (2) work in humid air and (3) completely liberate their captured particles in an aqueous solution compatible with the immunoassay technique. The immunoassay technology developed within this project combines electrophoretic capture with magnetic bead detection. It allows detection of as few as 150-600 analyte molecules or viruses in only three minutes, something no other known method can duplicate. The technology can be used in a variety of applications where speed of analysis and/or extremely low detection limits are of great importance: in rapid analysis of donor blood for hepatitis, HIV and other blood-borne infections in emergency blood transfusions, in trace analysis of pollutants, or in search of biomarkers in biological fluids. Combined in a single device, the water-soluble filter and ultra-sensitive immunoassay technique may solve the problem of early â??warning typeâ?ť detection of aerosolized pathogens. These two technologies are protected with five patent applications and are ready for commercialization.

  17. MDA-based ATL transformation to generate MVC 2 web models

    E-Print Network [OSTI]

    Rahmouni, M'hamed

    2011-01-01T23:59:59.000Z

    Development and maintenance of Web application is still a complex and error-prone process. We need integrated techniques and tool support for automated generation of Web systems and a ready prescription for easy maintenance. The MDA approach proposes an architecture taking into account the development and maintenance of large and complex software. In this paper, we apply MDA approach for generating PSM from UML design to MVC 2Web implementation. That is why we have developed two meta-models handling UML class diagrams and MVC 2 Web applications, then we have to set up transformation rules. These last are expressed in ATL language. To specify the transformation rules (especially CRUD methods) we used a UML profiles. To clearly illustrate the result generated by this transformation, we converted the XMI file generated in an EMF (Eclipse Modeling Framework) model.

  18. Usando MDA no Desenvolvimento de Sistemas Multi-Agentes Beatriz Alves De Maria Viviane Torres da Silva Carlos Jos Pereira de Lucena

    E-Print Network [OSTI]

    Endler, Markus

    Usando MDA no Desenvolvimento de Sistemas Multi-Agentes Beatriz Alves De Maria Viviane Torres da to support the development of multi-agents systems (MAS). In this paper, we propose the use of MDA in the development of this kind of systems. MDA specifies a structured software development process in modeling

  19. full potential of MDA, which allows for models at multiple layers of abstraction, and which has a meta-modelling and

    E-Print Network [OSTI]

    Pallis, George

    full potential of MDA, which allows for models at multiple layers of abstraction, and which has across GUI, OO implementation and databases without the role of MDA in separating these viewpoints being good introduction to the use of UML within a limited MDA framework. It provides an emphasis

  20. A CMOS Active Pixel Sensor for Charged Particle Detection

    SciTech Connect (OSTI)

    Matis, Howard S.; Bieser, Fred; Kleinfelder, Stuart; Rai, Gulshan; Retiere, Fabrice; Ritter, Hans George; Singh, Kunal; Wurzel, Samuel E.; Wieman, Howard; Yamamoto, Eugene

    2002-12-02T23:59:59.000Z

    Active Pixel Sensor (APS) technology has shown promise for next-generation vertex detectors. This paper discusses the design and testing of two generations of APS chips. Both are arrays of 128 by 128 pixels, each 20 by 20 {micro}m. Each array is divided into sub-arrays in which different sensor structures (4 in the first version and 16 in the second) and/or readout circuits are employed. Measurements of several of these structures under Fe{sup 55} exposure are reported. The sensors have also been irradiated by 55 MeV protons to test for radiation damage. The radiation increased the noise and reduced the signal. The noise can be explained by shot noise from the increased leakage current and the reduction in signal is due to charge being trapped in the epi layer. Nevertheless, the radiation effect is small for the expected exposures at RHIC and RHIC II. Finally, we describe our concept for mechanically supporting a thin silicon wafer in an actual detector.

  1. Tuned Lamb Wave Excitation and Detection with Piezoelectric Wafer Active Sensors for Structural Health Monitoring

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    and detect tuned Lamb waves for structural health monitoring is explored. First, a brief review of Lamb waves mode Lamb waves is demonstrated as an effective structural health monitoring method. Key Words: structural health monitoring, Lamb waves, piezoelectric wafer active sensors, aging aircraft, cracks, damage

  2. Eye Finding via Face Detection for a Foveated, Active Vision System Brian Scassellati

    E-Print Network [OSTI]

    Eye Finding via Face Detection for a Foveated, Active Vision System Brian Scassellati 545 Technology Square MIT Artificial Intelligence Lab Cambridge, MA, 02139, USA scaz@ai.mit.edu Abstract Eye finding is the first step toward building a ma- chine that can recognize social cues, like eye contact

  3. Eye Finding via Face Detection for a Foveated, Active Vision System Brian Scassellati

    E-Print Network [OSTI]

    Eye Finding via Face Detection for a Foveated, Active Vision System Brian Scassellati 545 Technology Square MIT Artificial Intelligence Lab Cambridge, MA, 02139, USA scaz@ai.mit.edu Abstract Eye finding is the first step toward building a ma­ chine that can recognize social cues, like eye contact

  4. MUSCLE ACTIVITY DETECTION FROM MYOELECTRIC SIGNALS BASED ON THE AR-GARCH MODEL

    E-Print Network [OSTI]

    Bouaynaya, Nidhal

    MUSCLE ACTIVITY DETECTION FROM MYOELECTRIC SIGNALS BASED ON THE AR-GARCH MODEL Ghulam Rasool Heteroscedastic (AR-GARCH) process, which captures the heteroscedasticity of the signal. The Akaike information cri- terion test confirms that the AR-GARCH model better fits the EMG signal than the stationary AR

  5. Title: Corrosion Damage Detection with Piezoelectric Wafer Active Sensors Authors: Dustin T. Thomas

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    0 Title: Corrosion Damage Detection with Piezoelectric Wafer Active Sensors Authors: Dustin T structural problems is corrosion. In fact the KC-135 now costs $1.2 billion a year to repair corrosion) in a pitch-catch configuration. The sensors were placed on a grid pattern. Material loss through corrosion

  6. Corrosion Damage Detection with Piezoelectric Wafer Active Sensors Dustin Thomas, John Welter

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    1 Corrosion Damage Detection with Piezoelectric Wafer Active Sensors Dustin Thomas, John Welter Air a priority issue for today's Air Force. One of the most critical structural problems is corrosion. In fact the KC-135 now costs $1.2 billion a year to repair corrosion. In this paper, we plan to show the use

  7. The Detection of Thyroid Receptor-Mediated Transcriptional Activity in Treated Peter Littlehat, Jr.

    E-Print Network [OSTI]

    Fay, Noah

    The Detection of Thyroid Receptor-Mediated Transcriptional Activity in Treated Wastewater by Peter) and other trace organic compounds that are released to the environment in treated domestic wastewaters of the thyroid hormone compounds under the two conditions, (ii) screen and compare the responsiveness of treated

  8. Chemical hazard evaluation of material disposal area (MDA) B closure project

    SciTech Connect (OSTI)

    Laul, Jagdish C [Los Alamos National Laboratory

    2010-04-19T23:59:59.000Z

    TA-21, MDA-B (NES) is the 'contaminated dump,' landfill with radionuclides and chemicals from process waste disposed in 1940s. This paper focuses on chemical hazard categorization and hazard evaluation of chemicals of concern (e.g., peroxide, beryllium). About 170 chemicals were disposed in the landfill. Chemicals included products, unused and residual chemicals, spent, waste chemicals, non-flammable oils, mineral oil, etc. MDA-B was considered a High hazard site. However, based on historical records and best engineering judgment, the chemical contents are probably at best 5% of the chemical inventory. Many chemicals probably have oxidized, degraded or evaporated for volatile elements due to some fire and limited shelf-life over 60 yrs, which made it possible to downgrade from High to Low chemical hazard site. Knowing the site history and physical and chemical properties are very important in characterizing a NES site. Public site boundary is only 20 m, which is a major concern. Chemicals of concern during remediation are peroxide that can cause potential explosion and beryllium exposure due to chronic beryllium disease (CBD). These can be prevented or mitigated using engineering control (EC) and safety management program (SMP) to protect the involved workers and public.

  9. Photo-activated luminescence sensor and method of detecting trichloroethylene and related volatile organochloride compounds

    DOE Patents [OSTI]

    Dinh, Tuan V. (Knoxville, TN)

    1996-01-01T23:59:59.000Z

    A sensor for detecting trichloroethylene and related volatile organochloride compounds uses a photo-activator that produces a photo-product complex with the contaminant. Characteristics of the light emitted from the complex will indicate the presence of the contaminant. A probe containing the photo-activator has an excitation light interface and a contaminant interface. One particular embodiment uses a porous membrane as the contaminant interface, so that the contaminant can migrate therethrough to the photo-activator and thereby form the complex.

  10. Photo-activated luminescence sensor and method of detecting trichloroethylene and related volatile organochloride compounds

    DOE Patents [OSTI]

    Dinh, T.V.

    1996-06-11T23:59:59.000Z

    A sensor for detecting trichloroethylene and related volatile organochloride compounds uses a photo-activator that produces a photo-product complex with the contaminant. Characteristics of the light emitted from the complex will indicate the presence of the contaminant. A probe containing the photo-activator has an excitation light interface and a contaminant interface. One particular embodiment uses a porous membrane as the contaminant interface, so that the contaminant can migrate there through to the photo-activator and thereby form the complex. 23 figs.

  11. Methods, microfluidic devices, and systems for detection of an active enzymatic agent

    DOE Patents [OSTI]

    Sommer, Gregory J; Hatch, Anson V; Singh, Anup K; Wang, Ying-Chih

    2014-10-28T23:59:59.000Z

    Embodiments of the present invention provide methods, microfluidic devices, and systems for the detection of an active target agent in a fluid sample. A substrate molecule is used that contains a sequence which may cleave in the presence of an active target agent. A SNAP25 sequence is described, for example, that may be cleaved in the presence of Botulinum Neurotoxin. The substrate molecule includes a reporter moiety. The substrate molecule is exposed to the sample, and resulting reaction products separated using electrophoretic separation. The elution time of the reporter moiety may be utilized to identify the presence or absence of the active target agent.

  12. Innovative high pressure gas MEM's based neutron detector for ICF and active SNM detection.

    SciTech Connect (OSTI)

    Martin, Shawn Bryan; Derzon, Mark Steven; Renzi, Ronald F.; Chandler, Gordon Andrew

    2007-12-01T23:59:59.000Z

    An innovative helium3 high pressure gas detection system, made possible by utilizing Sandia's expertise in Micro-electrical Mechanical fluidic systems, is proposed which appears to have many beneficial performance characteristics with regards to making these neutron measurements in the high bremsstrahlung and electrical noise environments found in High Energy Density Physics experiments and especially on the very high noise environment generated on the fast pulsed power experiments performed here at Sandia. This same system may dramatically improve active WMD and contraband detection as well when employed with ultrafast (10-50 ns) pulsed neutron sources.

  13. Estimation of the Performance of Multiple Active Neutron Interrogation Signatures for Detecting Shielded HEU

    SciTech Connect (OSTI)

    David L. Chichester; Scott J. Thompson; Scott M. Watson; James T. Johnson; Edward H. Seabury

    2012-10-01T23:59:59.000Z

    A comprehensive modeling study has been carried out to evaluate the utility of multiple active neutron interrogation signatures for detecting shielded highly enriched uranium (HEU). The modeling effort focused on varying HEU masses from 1 kg to 20 kg; varying types of shields including wood, steel, cement, polyethylene, and borated polyethylene; varying depths of the HEU in the shields, and varying engineered shields immediately surrounding the HEU including steel, tungsten, and cadmium. Neutron and gamma-ray signatures were the focus of the study and false negative detection probabilities versus measurement time were used as a performance metric. To facilitate comparisons among different approaches an automated method was developed to generate receiver operating characteristic (ROC) curves for different sets of model variables for multiple background count rate conditions. This paper summarizes results or the analysis, including laboratory benchmark comparisons between simulations and experiments. The important impact engineered shields can play towards degrading detectability and methods for mitigating this will be discussed.

  14. Adaptation of an enzyme-linked immunosorbent assay for detecting Brucella antibody activity in reindeer sera

    E-Print Network [OSTI]

    Perry, Dana Lynn

    1982-01-01T23:59:59.000Z

    of CF Positive Sera vs. ELISA Results Expressed as L Agreement ----- 23 Vaccinated Reindeer: Distribution of SPTA Negat1ve Sera vs. ELISA Results Expressed as X Agreement -- ? - 24 Vacc1nated Reindeer: Distr1bution of SPTB Negative Sera vs. ELISA... and content by: (Chairman of Committee) Member Head of D rtment December l982 ABSTRACT Adaptation of an Enzyme-Linked Immunosorbent Assay for Detecting Brucella Antibody Activity in Reindeer Sera. (December 1982) Dana Lynn Perry, B. S. , Texas A...

  15. Using Electronic Neutron Generators in Active Interrogation to Detect Shielded Fissionable Material

    SciTech Connect (OSTI)

    D. L. Chichester; E. H. Seabury

    2008-10-01T23:59:59.000Z

    Experiments have been performed at Idaho National Laboratory to study methodology and instrumentation for performing neutron active interrogation die-away analyses for the purpose of detecting shielded fissionable material. Here we report initial work using a portable DT electronic neutron generator with a He-3 fast neutron detector to detect shielded fissionable material including >2 kg quantities of enriched uranium and plutonium. Measurements have been taken of bare material as well as of material hidden within a large plywood cube. Results from this work have demonstrated the efficacy of the die-away neutron measurement technique for quickly detecting the presence of special nuclear material hidden within plywood shields by analyzing the time dependent neutron signals in-between neutron generator pulses. Using a DT electronic neutron generator operating at 300 Hz with a yield of approximately 0.36 x 10**8 neutrons per second, 2.2 kg of enriched uranium hidden within a 0.60 m x 0.60 m x 0.70 m volume of plywood was positively detected with a measurement signal 2-sigma above the passive background within 1 second. Similarly, for a 500 second measurement period a lower detection limit of approaching the gram level could be expected with the same simple set-up.

  16. Optically Detected Magnetic Resonance and Thermal Activation Spectroscopy Study of Organic Semiconductors

    SciTech Connect (OSTI)

    Chang-Hwan Kim

    2003-12-12T23:59:59.000Z

    Organic electronic materials are a new class of emerging materials. Organic light emitting devices (OLEDs) are the most promising candidates for future flat panel display technologies. The photophysical characterization is the basic research step one must follow to understand this new class of materials and devices. The light emission properties are closely related to the transport properties of these materials. The objective of this dissertation is to probe the relation between transport and photophysical properties of organic semiconductors. The transport characteristics were evaluated by using thermally stimulated current and thermally stimulated luminescence techniques. The photoluminescence detected magnetic resonance and photoluminescence quantum yield studies provide valuable photophysical information on this class of materials. OLEDs are already in the market. However, detailed studies on the degradation mechanisms are still lacking. Since both optically detected magnetic resonance and thermal activation spectroscopy probe long-lived defect-related states in organic semiconductors, the combined study generates new insight on the OLED operation and degradation mechanisms.

  17. A NEW MULTI-BAND RADIAL VELOCITY TECHNIQUE FOR DETECTING EXOPLANETS AROUND ACTIVE STARS

    SciTech Connect (OSTI)

    Ma Bo; Ge Jian, E-mail: boma@astro.ufl.edu, E-mail: jge@astrto.ufl.edu [Department of Astronomy, University of Florida, 211 Bryant Space Science Center, Gainesville, FL 32611 (United States)

    2012-05-10T23:59:59.000Z

    The radial velocity (RV) technique is one of the most efficient ways of detecting exoplanets. However, large RV jitters induced by starspots on an active star can inhibit detection of any exoplanet present or even lead to a false positive detection. This paper presents a new multi-band RV technique capable of substantially reducing starspot-induced RV jitters from stellar RV measurements to allow efficient and accurate extraction of RV signals caused by exoplanets. It takes full advantage of the correlation of RV jitters at different spectral bands and the independence of exoplanet signals at the corresponding bands. Simulations with a single-spot model and a multi-spot model have been conducted to investigate the RV jitter reduction capability of this method. The results show that this method can reduce the RV jitter amplitude by at least an order of magnitude, allowing detection of weaker exoplanet signals without significantly increasing RV observation time and cadence. This method can greatly reduce the observation time required to detect Earth-like planets around solar type stars with {approx}0.1 m s{sup -1} long term Doppler precision if spot-induced jitter is the dominant astrophysical noise source for RV measurements. This method can work efficiently for RV jitter removal if: (1) all the spots on a target star have approximately the same temperature during RV observations; (2) the RV jitter amplitude changes with wavelength, i.e., the RV jitter amplitude ratio, {alpha}, between two different spectral bands is not close to one; (3) the spot-induced RV jitter dominates the RV measurement error.

  18. Title: Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high intensity

    E-Print Network [OSTI]

    Boyer, Edmond

    1 Title: Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high intensity ultrasound Authors: Jérôme GATEAU, Jean-François AUBRY, Mathieu PERNOT / INSERM, U979 / Université Denis Diderot, Paris VII Key words: single nucleation events, ultrafast active

  19. EVIDENCE FOR THE IMPACT OF STELLAR ACTIVITY ON THE DETECTABILITY OF SOLAR-LIKE OSCILLATIONS OBSERVED BY KEPLER

    SciTech Connect (OSTI)

    Chaplin, W. J.; Broomhall, A.-M.; Hekker, S.; Elsworth, Y.; Stevens, I. R. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham, B15 2TT (United Kingdom); Bedding, T. R.; Huber, D. [Sydney Institute for Astronomy (SIfA), School of Physics, University of Sydney, NSW 2006 (Australia); Bonanno, A. [INAF Osservatorio Astrofisico di Catania, Via S. Sofia 78, 95123, Catania (Italy); GarcIa, R. A. [Laboratoire AIM, CEA/DSM, CNRS, Universite Paris Diderot, IRFU/SAp, 91191 Gif-sur-Yvette Cedex (France); Verner, G. A. [Astronomy Unit, Queen Mary, University of London, Mile End Road, London, E1 4NS (United Kingdom); Basu, S. [Department of Astronomy, Yale University, P.O. Box 208101, New Haven, CT 06520-8101 (United States); Houdek, G. [Institute of Astronomy, University of Vienna, A-1180 Vienna (Austria); Mathur, S.; Metcalfe, T. S. [High Altitude Observatory and, Scientific Computing Division, National Center for Atmospheric Research, Boulder, Colorado 80307 (United States); Mosser, B. [LESIA, CNRS, Universite Pierre et Marie Curie, Universite Denis Diderot, Observatoire de Paris, 92195 Meudon Cedex (France); New, R. [Materials Engineering Research Institute, Faculty of Arts, Computing, Engineering and Sciences, Sheffield Hallam University, Sheffield, S1 1WB (United Kingdom); Appourchaux, T. [Institut d'Astrophysique Spatiale, Universite Paris XI, CNRS (UMR8617), Batiment 121, 91405 Orsay Cedex (France); Karoff, C. [Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Molenda-Zakowicz, J. [Astronomical Institute, University of Wroclaw, ul. Kopernika, 11, 51-622 Wroclaw (Poland); Monteiro, M. J. P. F. G. [Centro de Astrofisica and Faculdade de Ciencias, Universidade do Porto, Rua das Estrelas, 4150-762 (Portugal)

    2011-05-01T23:59:59.000Z

    We use photometric observations of solar-type stars, made by the NASA Kepler Mission, to conduct a statistical study of the impact of stellar surface activity on the detectability of solar-like oscillations. We find that the number of stars with detected oscillations falls significantly with increasing levels of activity. The results present strong evidence for the impact of magnetic activity on the properties of near-surface convection in the stars, which appears to inhibit the amplitudes of the stochastically excited, intrinsically damped solar-like oscillations.

  20. Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: Role of ?-catenin/connexin43 association

    SciTech Connect (OSTI)

    Talhouk, Rabih S., E-mail: rtalhouk@aub.edu.lb [Department of Biology, Faculty of Arts and Sciences, American University of Beirut, P.O. Box 11-0236, Beirut (Lebanon); Fares, Mohamed-Bilal; Rahme, Gilbert J.; Hariri, Hanaa H.; Rayess, Tina; Dbouk, Hashem A.; Bazzoun, Dana; Al-Labban, Dania [Department of Biology, Faculty of Arts and Sciences, American University of Beirut, P.O. Box 11-0236, Beirut (Lebanon); El-Sabban, Marwan E., E-mail: me00@aub.edu.lb [Department of Anatomy, Cell Biology and Physiology, Faculty of Medicine, American University of Beirut, P.O. Box 11-0236, Beirut (Lebanon)

    2013-12-10T23:59:59.000Z

    Connexins (Cx), gap junction (GJ) proteins, are regarded as tumor suppressors, and Cx43 expression is often down regulated in breast tumors. We assessed the effect of Cx43 over-expression in 2D and 3D cultures of two breast adenocarcinoma cell lines: MCF-7 and MDA-MB-231. While Cx43 over-expression decreased proliferation of 2D and 3D cultures of MCF-7 by 56% and 80% respectively, MDA-MB-231 growth was not altered in 2D cultures, but exhibited 35% reduction in 3D cultures. C-terminus truncated Cx43 did not alter proliferation. Untransfected MCF-7 cells formed spherical aggregates in 3D cultures, and MDA-MB-231 cells formed stellar aggregates. However, MCF-7 cells over-expressing Cx43 formed smaller sized clusters and Cx43 expressing MDA-MB-231 cells lost their stellar morphology. Extravasation ability of both MCF-7 and MDA-MB-231 cells was reduced by 60% and 30% respectively. On the other hand, silencing Cx43 in MCF10A cells, nonneoplastic human mammary cell line, increased proliferation in both 2D and 3D cultures, and disrupted acinar morphology. Although Cx43 over-expression did not affect total levels of ?-catenin, ?-catenin and ZO-2, it decreased nuclear levels of ?-catenin in 2D and 3D cultures of MCF-7 cells, and in 3D cultures of MDA-MB-231 cells. Cx43 associated at the membrane with ?-catenin, ?-catenin and ZO-2 in 2D and 3D cultures of MCF-7 cells, and only in 3D conditions in MDA-MB-231 cells. This study suggests that Cx43 exerts tumor suppressive effects in a context-dependent manner where GJ assembly with ?-catenin, ?-catenin and ZO-2 may be implicated in reducing growth rate, invasiveness, and, malignant phenotype of 2D and 3D cultures of MCF-7 cells, and 3D cultures of MDA-MB-231 cells, by sequestering ?-catenin away from nucleus. - Highlights: • Cx43 over-expressing MCF-7 and MDA-MB-231 were grown in 2D and 3D cultures. • Proliferation and growth morphology were affected in a context dependent manner. • Extravasation ability of both MCF-7 and MDA-MB-231 cells was reduced. • Cx43-mediated gap junction complex assembly correlated with observed changes. • We propose that membranous Cx43 sequesters ?-catenin away from the nucleus.

  1. X-ray Detections of Sub-millimetre Galaxies: Active Galactic Nuclei Versus Starburst Contribution

    E-Print Network [OSTI]

    Johnson, Seth P; Wang, Danial Q; Williams, Christina C; Scott, Kim S; Yun, Min S; Pope, Alexandra; Lowenthal, James; Aretxaga, Itziar; Hughes, David; Kim, M J; Kim, Sungeun; Tamura, Yoichi; Kohno, Kotaro; Ezawa, Hajime; Kawabe, Ryohei; Oshima, Tai; 10.1093/mnras/stt197

    2013-01-01T23:59:59.000Z

    We present a large-scale study of the X-ray properties and near-IR-to-radio SEDs of submillimetre galaxies (SMGs) detected at 1.1mm with the AzTEC instrument across a ~1.2 square degree area of the sky. Combining deep 2-4 Ms Chandra data with Spitzer IRAC/MIPS and VLA data within the GOODS-N/S and COSMOS fields, we find evidence for AGN activity in ~14 percent of 271 AzTEC SMGs, ~28 percent considering only the two GOODS fields. Through X-ray spectral modeling and SED fitting using Monte Carlo Markov Chain techniques to Siebenmorgen et al. (2004) (AGN) and Efstathiou et al. (2000) (starburst) templates, we find that while star formation dominates the IR emission, with SFRs ~100-1000 M_sun/yr, the X-ray emission for most sources is almost exclusively from obscured AGNs, with column densities in excess of 10^23 cm^-2. Only for ~6 percent of our sources do we find an X-ray-derived SFR consistent with NIR-to-radio SED derived SFRs. Inclusion of the X-ray luminosities as a prior to the NIR-to-radio SED effectively...

  2. IEEE JOURNAL OF OCEANIC ENGINEERING, VOL.XXX, NO.XXX, XXX 1 Active Detection With A Barrier Sensor Network

    E-Print Network [OSTI]

    Zhou, Shengli

    IEEE JOURNAL OF OCEANIC ENGINEERING, VOL.XXX, NO.XXX, XXX 1 Active Detection With A Barrier Sensor of publication XXX; date of current version XXX. This work was supported by the U.S. Office of Naval Research in this paper are available online at http://ieeexplore.ieee.org. Digital Object Identifier XXX source target

  3. Improved Design of Active Pixel CMOS Sensors for Charged Particle Detection

    SciTech Connect (OSTI)

    Deptuch, Grzegorz

    2007-11-12T23:59:59.000Z

    The Department of Energy (DOE) nuclear physics program requires developments in detector instrumentation electronics with improved energy, position and timing resolution, sensitivity, rate capability, stability, dynamic range, and background suppression. The current Phase-I project was focused on analysis of standard-CMOS photogate Active Pixel Sensors (APS) as an efficient solution to this challenge. The advantages of the CMOS APS over traditional hybrid approaches (i.e., separate detection regions bump-bonded to readout circuits) include greatly reduced cost, low power and the potential for vastly larger pixel counts and densities. However, challenges remain in terms of the signal-to-noise ratio (SNR) and readout speed (currently on the order of milliseconds), which is the major problem for this technology. Recent work has shown that the long readout time for photogate APS is due to the presence of (interface) traps at the semiconductor-oxide interface. This Phase-I work yielded useful results in two areas: (a) Advanced three-dimensional (3D) physics-based simulation models and simulation-based analysis of the impact of interface trap density on the transient charge collection characteristics of existing APS structures; and (b) Preliminary analysis of the feasibility of an improved photogate pixel structure (i.e., new APS design) with an induced electric field under the charge collecting electrode to enhance charge collection. Significant effort was dedicated in Phase-I to the critical task of implementing accurate interface trap models in CFDRC's NanoTCAD 3D semiconductor device-physics simulator. This resulted in validation of the new NanoTCAD models and simulation results against experimental (published) data, within the margin of uncertainty associated with obtaining device geometry, material properties, and experimentation details. Analyses of the new, proposed photogate APS design demonstrated several promising trends.

  4. Prolactin receptor attenuation induces zinc pool redistribution through ZnT2 and decreases invasion in MDA-MB-453 breast cancer cells

    SciTech Connect (OSTI)

    Bostanci, Zeynep, E-mail: zbostanci@hmc.psu.edu [The Pennsylvania State University, Department of Nutritional Sciences, 209 Chandlee Lab, University Park, PA 16802 (United States); The Pennsylvania State University Milton S. Hershey Medical Center, Department of Surgery, 500 University Dr., Hershey, PA 17033 (United States); Alam, Samina, E-mail: sra116@psu.edu [The Pennsylvania State University, Department of Nutritional Sciences, 209 Chandlee Lab, University Park, PA 16802 (United States); The Pennsylvania State University Milton S. Hershey Medical Center, Department of Surgery, 500 University Dr., Hershey, PA 17033 (United States); Soybel, David I., E-mail: dsoybel@hmc.psu.edu [The Pennsylvania State University, Department of Nutritional Sciences, 209 Chandlee Lab, University Park, PA 16802 (United States); The Pennsylvania State University Milton S. Hershey Medical Center, Department of Surgery, 500 University Dr., Hershey, PA 17033 (United States); The Pennsylvania State University College of Medicine, Department of Cell and Molecular Physiology, 500 University Dr., Hershey, PA 17033 (United States); Kelleher, Shannon L., E-mail: slk39@psu.edu [The Pennsylvania State University, Department of Nutritional Sciences, 209 Chandlee Lab, University Park, PA 16802 (United States); The Pennsylvania State University Milton S. Hershey Medical Center, Department of Surgery, 500 University Dr., Hershey, PA 17033 (United States); The Pennsylvania State University College of Medicine, Department of Cell and Molecular Physiology, 500 University Dr., Hershey, PA 17033 (United States)

    2014-02-15T23:59:59.000Z

    Prolactin receptor (PRL-R) activation regulates cell differentiation, proliferation, cell survival and motility of breast cells. Prolactin (PRL) and PRL-R over-expression are strongly implicated in breast cancer, particularly contributing to tumor growth and invasion in the more aggressive estrogen-receptor negative (ER?) disease. PRL-R antagonists have been suggested as potential therapeutic agents; however, mechanisms through which PRL-R antagonists exert their actions are not well-understood. Zinc (Zn) is a regulatory factor for over 10% of the proteome, regulating critical cell processes such as proliferation, cell signaling, transcription, apoptosis and autophagy. PRL-R signaling regulates Zn metabolism in breast cells. Herein we determined effects of PRL-R attenuation on cellular Zn metabolism and cell function in a model of ER-, PRL-R over-expressing breast cancer cells (MDA-MB-453). PRL-R attenuation post-transcriptionally increased ZnT2 abundance and redistributed intracellular Zn pools into lysosomes and mitochondria. ZnT2-mediated lysosomal Zn sequestration was associated with reduced matrix metalloproteinase 2 (MMP-2) activity and decreased invasion. ZnT2-mediated Zn accumulation in mitochondria was associated with increased mitochondrial oxidation. Our results suggest that PRL-R antagonism in PRL-R over-expressing breast cancer cells may reduce invasion through the redistribution of intracellular Zn pools critical for cellular function. - Highlights: • PRL-R attenuation increased ZnT2 expression. • PRL-R attenuation increased lysosomal and mitochondrial Zn accumulation. • PRL-R attenuation decreased MMP-2 and invasion. • PRL-R antagonists may modulate lysosomal and mitochondrial Zn pools.

  5. Real-time detection of malicious network activity using stochastic models

    E-Print Network [OSTI]

    Jung, Jaeyeon, Ph. D. Massachusetts Institute of Technology

    2006-01-01T23:59:59.000Z

    This dissertation develops approaches to rapidly detect malicious network traffic including packets sent by portscanners and network worms. The main hypothesis is that stochastic models capturing a host's particular ...

  6. A Multi-Mode Sensing System for Corrosion Detection Using Piezoelectric Wafer Active Sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    methods, including ultrasonic, impedance, and thickness measurement, we introduce the concept of PWAS Columbia, SC 29208, pollocpj@engr.sc.edu ABSTRACT As an emerging technology for in-situ damage detection in propagating wave mode or electromechanical impedance mode. Its small size and low cost (about ~$10 each) make

  7. Multi-mode Damage Detection Methods with Piezoelectric Wafer Active Sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    impedance measurements; (3) PWAS ultrasonic SHM/NDE; and (4) PWAS multi-mode corrosion detection multiple modes in situ SHM methods using PWAS transducers with impedance, pitch- catch, and/or pulse transducers for impedance measure- ment and ultrasonic inspection are given first. Then several examples

  8. Hypoxia activated cell signaling receptors in cancer

    E-Print Network [OSTI]

    Lester, Robin D.

    2008-01-01T23:59:59.000Z

    cancer cells MCF-7 and MDA- MB-231. Biomed. Pharmacother.and prevents apoptosis in MDA-MB-231 breast cancer cells. J.Gaithersburg, MD). Cell Culture MDA-MB-468, MDA-MB-435, ZR-

  9. Stellar Activity and its Implications for Exoplanet Detection on GJ 176

    E-Print Network [OSTI]

    Robertson, Paul; Henry, Gregory W; Cochran, William D; MacQueen, Phillip J; Williamson, Michael H

    2015-01-01T23:59:59.000Z

    We present an in-depth analysis of stellar activity and its effects on radial velocity (RV) for the M2 dwarf GJ 176 based on spectra taken over 10 years from the High Resolution Spectrograph on the Hobby-Eberly Telescope. These data are supplemented with spectra from previous observations with the HIRES and HARPS spectrographs, and V- and R-band photometry taken over 6 years at the Dyer and Fairborn observatories. Previous studies of GJ 176 revealed a super-Earth exoplanet in an 8.8-day orbit. However, the velocities of this star are also known to be contaminated by activity, particularly at the 39-day stellar rotation period. We have examined the magnetic activity of GJ 176 using the sodium I D lines, which have been shown to be a sensitive activity tracer in cool stars. In addition to rotational modulation, we see evidence of a long-term trend in our Na I D index, which may be part of a long-period activity cycle. The sodium index is well correlated with our RVs, and we show that this activity trend drives ...

  10. Detection of frozen salt in pipes using gamma-ray spectrometry of potassium self-activity

    SciTech Connect (OSTI)

    Grena, Roberto; Scafe, Raffaele; Pisacane, Fabrizio; Pilato, Renzo; Crescenzi, Tommaso; Mazzei, Domenico [ENEA, Casaccia Research Centre, via Anguillarese 301, 00123 S. Maria di Galeria, Rome (Italy)

    2010-01-15T23:59:59.000Z

    Solar plants that use molten salts as heat transfer fluid need careful control to avoid the freezing of the salt in the pipes; if such a problem occurs, a diagnostic instrument to localize where is the frozen salt plug and to determine its length is useful. If the salt contains potassium (as is the case of the most common mixture used in solar plants, NaNO{sub 3}/KNO{sub 3} 60/40% by weight), the gamma decay of the natural unstable isotope {sup 40}K can be exploited to detect the frozen salt in a non-invasive way. Simulations and experimental results regarding the detectability of such plugs with different masses/lengths are presented. (author)

  11. An active system for the detection of special fissile material in small watercraft 

    E-Print Network [OSTI]

    Johansen, Norman Alfan, III

    2006-10-30T23:59:59.000Z

    FM Fissile material HEU Highly enriched uranium IAEA International Atomic Energy Agency keV kiloelectronvolt kV kilovolt MCNP Monte Carlo N-Particle MeV Megaelectronvolt NAA Neutron activation analysis NDA Non-destructive analysis PNG....5.1. Required source strength for HEU.....................................................................61 IV.5.2. Required source strength for plutonium............................................................64 IV.6. Passive plutonium...

  12. MDA - 0112.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this issue:^J MASTER

  13. MDA - 0203.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this issue:^J MASTER2nd Quarter

  14. MDA - 0206.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this issue:^J MASTER2nd Quarter3rd

  15. MDA - 0212.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this issue:^J MASTER2nd

  16. MDA - 0303.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this issue:^J

  17. MDA - 0306.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this

  18. MDA - 0312.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this3, BPA earned net revenues of

  19. MDA0006.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this3, BPA earned net revenues

  20. MDA0012.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this3, BPA earned net revenues1st

  1. MDA0103.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this3, BPA earned net

  2. Development of atomic layer deposition-activated microchannel plates for single particle detection at cryogenic temperatures

    SciTech Connect (OSTI)

    Gorelikov, Dmitry, E-mail: dmitry@arradiance.com; Sullivan, Neal; Rouffignac, Philippe de; Li, Huazhi; Narayanamoorthy, Jayasri; Tremsin, Anton S. [Arradiance Inc., 142 North Road, Sudbury, Massachusetts 01776 (United States)

    2014-03-15T23:59:59.000Z

    Atomic layer deposition (ALD) technology is used to nanoengineer functional films inside the pores of microchannel plate (MCP) electron multipliers, enabling a novel MCP manufacturing technology that substantially improves performance and opens novel applications. The authors have developed custom tools and recipes for the growth of conformal films, with optimized conductance and secondary electron emission inside very long channels (?6–20??m diameter and >600??m length, with tens of millions of channels per single MCP) by ALD. The unique ability to tune the characteristics of these ALD films enables their optimization to applications where time-resolved single particle imaging can be performed in extreme conditions, such as high counting rates at cryogenic temperatures. Adhesion of the conductive and emissive nanofilms to the 20??m pore MCP glass substrates and their mechanical stability over a very wide range of temperatures (10–700?K) were confirmed experimentally. Resistance of ALD MCPs was reproducible during multiple cool-down cycles with no film degradation observed. Optimizing resistance of novel MCPs for operation at cryogenic temperature should enable high count rate event detection at temperatures below 20?K.

  3. Parametric Evaluation of Active Neutron Interrogation for the Detection of Shielded Highly-Enriched Uranium in the Field

    SciTech Connect (OSTI)

    D. L. Chcihester; E. H. Seabury; S. J. Thompson; R. R. C. Clement

    2011-10-01T23:59:59.000Z

    Parametric studies using numerical simulations are being performed to assess the performance capabilities and limits of active neutron interrogation for detecting shielded highly enriched uranium (HEU). Varying the shield material, HEU mass, HEU depth inside the shield, and interrogating neutron source energy, the simulations account for both neutron and photon emission signatures from the HEU with resolution in both energy and time. The results are processed to represent different irradiation timing schemes and several different classes of radiation detectors, and evaluated using a statistical approach considering signal intensity over background. This paper describes the details of the modeling campaign and some preliminary results, weighing the strengths of alternative measurement approaches for the different irradiation scenarios.

  4. Detection of Anomalous Reactor Activity Using Antineutrino Count Rate Evolution Over the Course of a Reactor Cycle

    E-Print Network [OSTI]

    Vera Bulaevskaya; Adam Bernstein

    2010-09-11T23:59:59.000Z

    This paper analyzes the sensitivity of antineutrino count rate measurements to changes in the fissile content of civil power reactors. Such measurements may be useful in IAEA reactor safeguards applications. We introduce a hypothesis testing procedure to identify statistically significant differences between the antineutrino count rate evolution of a standard 'baseline' fuel cycle and that of an anomalous cycle, in which plutonium is removed and replaced with an equivalent fissile worth of uranium. The test would allow an inspector to detect anomalous reactor activity, or to positively confirm that the reactor is operating in a manner consistent with its declared fuel inventory and power level. We show that with a reasonable choice of detector parameters, the test can detect replacement of 73 kg of plutonium in 90 days with 95% probability, while controlling the false positive rate at 5%. We show that some improvement on this level of sensitivity may be expected by various means, including use of the method in conjunction with existing reactor safeguards methods. We also identify a necessary and sufficient daily antineutrino count rate to achieve the quoted sensitivity, and list examples of detectors in which such rates have been attained.

  5. A ROBUST ABSOLUTE DETECTION EFFICIENCY CALIBRATION METHOD UTILIZING BETA/GAMMA COINCIDENCE SIGNATURES AND ISOTOPICALLY PURIFIED NEUTRON ACTIVATED RADIOXENON ISOTOPES

    SciTech Connect (OSTI)

    McIntyre, Justin I.; Cooper, Matthew W.; Ely, James H.; Haas, Derek A.; Schrom, Brian T.

    2012-09-21T23:59:59.000Z

    Efforts to calibrate the absolute efficiency of gas cell radiations detectors have utilized a number of methodologies which allow adequate calibration but are time consuming and prone to a host of difficult-to-determine uncertainties. A method that extrapolates the total source strength from the measured beta and gamma gated beta coincidence signal was developed in the 1960’s and 1970’s. It has become clear that it is possible to achieve more consistent results across a range of isotopes and a range of activities using this method. Even more compelling is the ease with which this process can be used on routine samples to determine the total activity present in the detector. Additionally, recent advances in the generation of isotopically pure radioxenon samples of Xe-131m, Xe-133, and Xe-135 have allowed these measurement techniques to achieve much better results than would have been possible before when using mixed isotopic radioxenon source. This paper will discuss the beta/gamma absolute detection efficiency technique that utilizes several of the beta-gamma decay signatures to more precisely determine the beta and gamma efficiencies. It will than compare these results with other methods using pure sources of Xe-133, Xe-131m, and Xe-135 and a Xe-133/Xe-133m mix.

  6. Packaging Waste and Hitting Home Runs: How Education and Lightning Strike Detection Technology Supports Company and Community Activities

    SciTech Connect (OSTI)

    Deecke, T.A. [Weston Solutions, Inc., 297 Kentucky Avenue, Kevil, KY 42053 (United States); Hyde, J.V.; Hylko, J.M. [WESKEM, LLC, 297 Kentucky Avenue, Kevil, KY 42053 (United States)

    2006-07-01T23:59:59.000Z

    The weather is the most significant and unmanageable variable when performing environmental remediation activities. This variable can contribute to the failure of a project in two ways: 1) severe injury to an employee or employees following a cloud-to-ground lightning strike without prior visual or audible warnings; and 2) excessive 'down time' associated with mobilization and demobilization activities after a false alarm (e.g., lightning was seen in the distance but was actually moving away from the site). Therefore, in order for a project to be successful from both safety and financial viewpoints, the uncertainties associated with inclement weather, specifically lightning, need to be understood to eliminate the element of surprise. This paper discusses educational information related to the history and research of lightning, how lightning storms develop, types of lightning, the mechanisms of lightning injuries and fatalities, and follow-up medical treatment. Fortunately, lightning storm monitoring does not have to be either costly or elaborate. WESKEM, LLC selected the Boltek StormTracker Lightning Detection System with the Aninoquisi Lightning 2000{sup TM} software. This fixed system, used in combination with online weather web pages, monitors and alarms WESKEM, LLC field personnel in the event of an approaching lightning storm. This application was expanded to justify the purchase of the hand-held Sky Scan Lightning/Storm Detector Model P5 used by the Heath Youth Athletic Association (HYAA) which is a non-profit, charitable organization offering sports programs for the youth and young adults in the local community. Fortunately, a lightning injury or fatality has never occurred on a WESKEM Paducah project or an HYAA-sponsored event. Using these fixed and hand-held systems will continue to prevent such injuries from occurring in the foreseeable future. (authors)

  7. Assessment of inhalation and ingestion doses from exposure to radon gas using passive and active detecting techniques

    SciTech Connect (OSTI)

    Ismail, A. H.; Jafaar, M. S. [Universiti Sains Malaysia, 11800 USM, Penang (Malaysia)

    2011-07-01T23:59:59.000Z

    The aim of this study was to assess an environmental hazard of radon exhalation rate from the samples of soil and drinking water in selected locations in Iraqi Kurdistan, passive (CR-39NTDs) and active (RAD7) detecting techniques has been employed. Long and short term measurements of emitted radon concentrations were estimated for 124 houses. High and lower radon concentration in soil samples was in the cities of Hajyawa and Er. Tyrawa, respectively. Moreover, for drinking water, high and low radon concentration was in the cities of Similan and Kelak, respectively. A comparison between our results with that mentioned in international reports had been done. Average annual dose equivalent to the bronchial epithelium, stomach and whole body in the cities of Kelak and Similan are estimated, and it was varied from 0.04{+-}0.01 mSv to 0.547{+-}0.018 mSv, (2.832{+-}0.22)x10{sup -5} to (11.972{+-}2.09)x10{sup -5} mSv, and (0.056 {+-}0.01) x10{sup -5} to (0.239{+-}0.01)x10{sup -5} mSv, respectively. This indicated that the effects of dissolved radon on the bronchial epithelium are much than on the stomach and whole body. (authors)

  8. Using the Sun to estimate Earth-like planets detection capabilities. V. Parameterizing the impact of solar activity components on radial velocities

    E-Print Network [OSTI]

    Borgniet, Simon; Lagrange, Anne-Marie

    2015-01-01T23:59:59.000Z

    Stellar activity induced by active structures (eg, spots, faculae) is known to strongly impact the radial velocity time series. It then limits the detection of small planetary RV signals (eg, an Earth-mass planet in the habitable zone of a solar-like star). In previous papers, we studied the detectability of such planets around the Sun seen as an edge-on star. For that purpose, we computed the RV and photometric variations induced by solar magnetic activity, using all active structures observed over one entire cycle. Our goal is to perform similar studies on stars with different physical and geometrical properties. As a first step, we focus on Sun-like stars seen with various inclinations, and on estimating detection capabilities with forthcoming instruments. To do so, we first parameterize the solar active structures with the most realistic pattern so as to obtain results consistent with the observed ones. We simulate the growth, evolution and decay of solar spots, faculae and network, using parameters and e...

  9. Laboratory and Field Testing of Commercially Available Detectors for the Identification of Chemicals of Interest in the Nuclear Fuel Cycle for the Detection of Undeclared Activities

    SciTech Connect (OSTI)

    Carla Miller; Mary Adamic; Stacey Barker; Barry Siskind; Joe Brady; Warren Stern; Heidi Smartt; Mike McDaniel; Mike Stern; Rollin Lakis

    2014-07-01T23:59:59.000Z

    Traditionally, IAEA inspectors have focused on the detection of nuclear indicators as part of infield inspection activities. The ability to rapidly detect and identify chemical as well as nuclear signatures can increase the ability of IAEA inspectors to detect undeclared activities at a site. Identification of chemical indicators have been limited to use in the analysis of environmental samples. Although IAEA analytical laboratories are highly effective, environmental sample processing does not allow for immediate or real-time results to an IAEA inspector at a facility. During a complementary access inspection, under the Additional Protocol, the use of fieldable technologies that can quickly provide accurate information on chemicals that may be indicative of undeclared activities can increase the ability of IAEA to effectively and efficiently complete their mission. The Complementary Access Working Group (CAWG) is a multi-laboratory team with members from Brookhaven National Laboratory, Idaho National Laboratory, Los Alamos National Laboratory, and Sandia National Laboratory. The team identified chemicals at each stage of the nuclear fuel cycle that may provide IAEA inspectors with indications that proliferation activities may be occurring. The group eliminated all indicators related to equipment, technology and training, developing a list of by-products/effluents, non-nuclear materials, nuclear materials, and other observables. These proliferation indicators were prioritized based on detectability from a conduct of operations (CONOPS) perspective of a CA inspection (for example, whether an inspector actually can access the S&O or whether it is in process with no physical access), and the IAEA’s interest in the detection technology in conjunction with radiation detectors. The list was consolidated to general categories (nuclear materials from a chemical detection technique, inorganic chemicals, organic chemicals, halogens, and miscellaneous materials). The team then identified commercial off the shelf (COTS) chemical detectors that may detect the chemicals of interest. Three chemical detectors were selected and tested both in laboratory settings and in field operations settings at Idaho National Laboratory. The instruments selected are: Thermo Scientific TruDefender FT (FTIR), Thermo Scientific FirstDefender RM (Raman), and Bruker Tracer III SD (XRF). Functional specifications, operability, and chemical detectability, selectivity, and limits of detection were determined. Results from the laboratory and field tests will be presented. This work is supported by the Next Generation Safeguards Initiative, Office of Nonproliferation and International Security, National Nuclear Security Administration.

  10. SGR J1550-5418 BURSTS DETECTED WITH THE FERMI GAMMA-RAY BURST MONITOR DURING ITS MOST PROLIFIC ACTIVITY

    SciTech Connect (OSTI)

    Van der Horst, A. J.; Finger, M. H. [Universities Space Research Association, NSSTC, Huntsville, AL 35805 (United States); Kouveliotou, C. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gorgone, N. M. [Connecticut College, New London, CT 06320 (United States); Kaneko, Y.; Goegues, E.; Lin, L. [Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I -Tuzla, Istanbul 34956 (Turkey); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Guiriec, S.; Bhat, P. N.; Chaplin, V. L.; Goldstein, A. [University of Alabama, Huntsville, CSPAR, Huntsville, AL 35805 (United States); Granot, J. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); Watts, A. L. [Astronomical Institute 'Anton Pannekoek', University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Bissaldi, E.; Gruber, D. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, 85748 Garching (Germany); Gehrels, N.; Harding, A. K. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Gibby, M. H.; Giles, M. M., E-mail: A.J.VanDerHorst@uva.nl [Jacobs Technology, Inc., Huntsville, AL (United States); and others

    2012-04-20T23:59:59.000Z

    We have performed detailed temporal and time-integrated spectral analysis of 286 bursts from SGR J1550-5418 detected with the Fermi Gamma-ray Burst Monitor (GBM) in 2009 January, resulting in the largest uniform sample of temporal and spectral properties of SGR J1550-5418 bursts. We have used the combination of broadband and high time-resolution data provided with GBM to perform statistical studies for the source properties. We determine the durations, emission times, duty cycles, and rise times for all bursts, and find that they are typical of SGR bursts. We explore various models in our spectral analysis, and conclude that the spectra of SGR J1550-5418 bursts in the 8-200 keV band are equally well described by optically thin thermal bremsstrahlung (OTTB), a power law (PL) with an exponential cutoff (Comptonized model), and two blackbody (BB) functions (BB+BB). In the spectral fits with the Comptonized model, we find a mean PL index of -0.92, close to the OTTB index of -1. We show that there is an anti-correlation between the Comptonized E{sub peak} and the burst fluence and average flux. For the BB+BB fits, we find that the fluences and emission areas of the two BB functions are correlated. The low-temperature BB has an emission area comparable to the neutron star surface area, independent of the temperature, while the high-temperature BB has a much smaller area and shows an anti-correlation between emission area and temperature. We compare the properties of these bursts with bursts observed from other SGR sources during extreme activations, and discuss the implications of our results in the context of magnetar burst models.

  11. AGILE detection of variable gamma-ray activity from the blazar S5 0716+714 in September-October 2007

    E-Print Network [OSTI]

    A. W. Chen; F. D'Ammando; M. Villata; C. M. Raiteri; M. Tavani; V. Vittorini; A. Bulgarelli; I. Donnarumma; A. Ferrari; A. Giuliani; F. Longo; L. Pacciani; G. Pucella; S. Vercellone; A. Argan; G. Barbiellini; F. Boffelli; P. Caraveo; D. Carosati; P. W. Cattaneo; V. Cocco; E. Costa; E. Del Monte; G. De Paris; G. Di Cocco; Y. Evangelista; M. Feroci; M. Fiorini; T. Froysland; M. Frutti; F. Fuschino; M. Galli; F. Gianotti; O. M. Kurtanidze; C. Labanti; I. Lapshov; V. M. Larionov; F. Lazzarotto; P. Lipari; M. Marisaldi; M. Mastropietro; S. Mereghetti; E. Morelli; A. Morselli; M. Pasanen; A. Pellizzoni; F. Perotti; P. Picozza; G. Porrovecchio; M. Prest; M. Rapisarda; A. Rappoldi; A. Rubini; P. Soffitta; M. Trifoglio; A. Trois; E. Vallazza; A. Zambra; D. Zanello; S. Cutini; D. Gasparrini; C. Pittori; P. Santolamazza; F. Verrecchia; P. Giommi; L. A. Antonelli; S. Colafrancesco; L. Salotti

    2008-08-29T23:59:59.000Z

    We report the gamma-ray activity from the intermediate BL Lac S5 0716+714 during observations acquired by the AGILE satellite in September and October 2007. These detections of activity were contemporaneous with a period of intense optical activity, which was monitored by GASP-WEBT. This simultaneous optical and gamma-ray coverage allows us to study in detail the light curves, time lags, gamma-ray photon spectrum, and Spectral Energy Distributions (SEDs) during different states of activity. AGILE observed the source with its two co-aligned imagers, the Gamma-Ray Imaging Detector (GRID) and the hard X-ray imager (Super-AGILE), which are sensitive to the 30 MeV-50 GeV and 18-60 keV energy ranges, respectively. Observations were completed in two different periods, the first between 2007 September 4-23, and the second between 2007 October 24-November 1. Over the period 2007 September 7-12, AGILE detected gamma-ray emission from the source at a significance level of 9.6-sigma with an average flux (E>100 MeV) of (97 +/- 15) x 10^{-8} photons cm^{-2} s^{-1}, which increased by a factor of at least four within three days. No emission was detected by Super-AGILE for the energy range 18-60 keV to a 3-sigma upper limit of 10 mCrab in 335 ksec. In October 2007, AGILE repointed toward S5 0716+714 following an intense optical flare, measuring an average flux of (47 +/- 11) x 10^{-8} photons cm^{-2} s^{-1} at a significance level of 6.0-sigma. The gamma-ray flux of S5 0716+714 detected by AGILE is the highest ever detected for this blazar and one of the most intense gamma-ray fluxes detected from a BL Lac object. The SED of mid-September appears to be consistent with the synchrotron self-Compton (SSC) emission model, but only by including two SSC components of different variabilities.

  12. Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer

    E-Print Network [OSTI]

    Ren, Yongsheng; Wu, Liyu; Frost, Andra R; Grizzle, William; Cao, Xu; Wan, Mei

    2009-01-01T23:59:59.000Z

    according to the manufac- turer's instructions. MDA-MB-231 and MDA-MB-468 cells were a gift from Dr. Josephcancer cell line (MCF-7, MDA-MB-231 or MDA-MB-468) cells

  13. AGILE detection of variable gamma-ray activity from the blazar S5 0716+714 during September-October 2007

    E-Print Network [OSTI]

    F. D'Ammando; A. W. Chen; M. Villata; C. M. Raiteri; V. Vittorini; A. Bulgarelli; I. Donnarumma; A. Giuliani; F. Longo; L. Pacciani; G. Pucella; M. Tavani; S. Vercellone

    2008-08-27T23:59:59.000Z

    We report the gamma-ray activity from the Intermediate BL Lac S5 0716+714 during 2007 September-October observations by the AGILE satellite, coincident with a period of intense optical activity of the source monitored by GASP-WEBT. AGILE observed the source with its two co-aligned imagers, the Gamma-Ray Imaging Detector (GRID) and the hard X-ray imager (Super-AGILE) sensitive in the energy range 30 MeV-50 GeV and 18-60 keV respectively, in two different periods: the first between 4 and 23 September 2007, the second between 24 October and 1 November 2007. Over the period 7-12 September, AGILE detected gamma-ray emission from the source at a significance level of 9.6-sigma with an average flux (E>100 MeV) of (97+/-15) x 10^{-8} photons cm^{-2} s^{-1}, increasing by a factor of at least four within three days. No emission was detected by Super-AGILE in the energy range 18-60 keV, with a 3-sigma upper limit of 10 mCrab in 335 ksec. The gamma-ray flux of S5 0716+714 detected by AGILE is the highest ever detected for this blazar and one of the most intense gamma-ray fluxes detected from a BL Lac object. The Spectral Energy Distribution (SED) of mid-September seems to be consistent with the synchrotron self-Compton (SSC) emission model, but only by including two SSC components with different variability. In October 2007 AGILE repointed toward S5 0716+714 following an intense optical flare, measuring an average flux of (47+/-11) x 10^{-8} photons cm^{-2} s^{-1} at a significance level of 6.0-sigma. The gamma-ray flux during both AGILE pointings appears to be highly variable on timescales of 1 day.

  14. IEEE Trans Ultrason Ferroelectr Freq Control . Author manuscript Combined passive detection and ultrafast active imaging of cavitation

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Gateaué ô Abstract The activation of natural gas nuclei to induce larger and ultrafast active imaging over a large volume and with the same multi-element probe. Bubble nucleation ; ultrasonography ; Phantoms, Imaging ; Sheep ; Signal Processing, Computer-Assisted ; Transducers ; Ultrasonography

  15. DOE/OR/07-2247&D1

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and decommissioning dpm disintegrations per minute EECA Engineering EvaluationCost Analysis FBP Fluor B&W Portsmouth, LLC MDA minimum detectable activity mgkg milligrams per...

  16. Automated detection and classification of circulating cancer cells via high-throughput microscopy

    E-Print Network [OSTI]

    Agustin, Ramses Martinez

    2007-01-01T23:59:59.000Z

    sample (1/100 dilution in MDA-MB-231) with highest positivesample (1/200 dilution in MDA-MB-231) with highest positivesample (1/200 dilution in MDA-MB-468) with highest positive

  17. Detection of estrogen- and dioxin-like activity in pulp and paper mill black liquor and effluent using in vitro bioassays

    SciTech Connect (OSTI)

    Zacharewski, T.; Berhane, K.; Gillesby, B.; Burnison, K. [Univ. of Western Ontario, London, Ontario (Canada). Dept. of Pharmacology and Toxicology; [National Water Research Inst., Burlington, Ontario (Canada). Aquatic Ecosystem Conservation Branch

    1995-12-31T23:59:59.000Z

    Pulp and paper mill effluent contains a complex mixture of compounds which adversely affect fish physiologically and at the population level. These effects include compromised reproductive fitness and the induction of mixed-function oxidase activities; two classic responses mediated by the estrogen and/or Ah receptor. In vitro recombinant receptor/reporter gene assays were used to examine pulp and paper mill black liquor and effluent for estrogenic, dioxin-like and antiestrogenic activities. Using MCF7 cells transiently transfected with a Gal4-estrogen receptor chimeric construct (Gal4-HEGO) and a Gal4-regulated luciferase reporter gene (17m5-G-Luc), it was estimated that black liquor contains 4 {+-} 2 ppb ``estrogen equivalents``, while negligible estrogenic activity was observed in a methanol-extracted pulp and paper mill effluent fraction (MF). A dioxin response element (DRE)-regulated luciferase reporter gene (pGudLucl.1) transiently transfected into Hepalclc7 wild type cells exhibited a dose-dependent increase in luciferase activity following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDO), black liquor and MF. Based on the dose response curves, black liquor and MF contain 10 {+-} 4 ppb and 20 {+-} 6 ppt ``TCDD equivalents``, respectively. Moreover, MF exhibited significant AhR-mediated antiestrogenic activity. These results demonstrate the utility of these bioassays and suggest that the effects observed in fish exposed to pulp and paper mill effluent may be due to unidentified ER and AhR ligands not detected by conventional chemical analysis due to the lack of appropriate chemical standards.

  18. Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane

    E-Print Network [OSTI]

    Chau, Ying

    a concen- tration of 5 Mmol/L, suppressed activity to MCF-7 and RBC was observed, whereas the toxicity of the cyclic peptide was shown by comparing cytotoxicity results on RBC and two human breast cancer cell lines of different malignancy and MT1-MMP expression: highly invasive MDA-MB-435 and noninvasive MCF-7. Above

  19. Predictive analysis of concealed social network activities based on communication technology choices: early-warning detection of attack signals from terrorist organizations

    E-Print Network [OSTI]

    Drozdova, Katya; Samoilov, Michael

    2010-01-01T23:59:59.000Z

    early-warning detection of attack signals from terroristtowards detecting terrorist attack precursors. We ?nd thatof impending terrorist attacks. (Such potential practical

  20. Radon detection

    DOE Patents [OSTI]

    MacArthur, D.W.; Allander, K.S.; Bounds, J.A.

    1994-01-25T23:59:59.000Z

    A detector for atmospheric radon using a long range alpha detector as its sensing element is described. An electrostatic filter removes ions from ambient air, while allowing radon atoms to pass into a decay cavity. Here, radon atoms are allowed to decay, creating air ions. These air ions are drawn by a fan through a second electrostatic filter which can be activated or deactivated, and into the long range alpha detector. With the second electrostatic filter activated, no air ions are allowed to pass, and the signal output from the long range alpha detector consists of only the electronic background. With the second electrostatic filter deactivated, air ions and cosmic rays will be detected. The cosmic ray contribution can be minimized by shielding. 3 figures.

  1. Remote detection of fissile material : Cherenkov counters for gamma detection

    E-Print Network [OSTI]

    Erickson, Anna S

    2011-01-01T23:59:59.000Z

    The need for large-size detectors for long-range active interrogation (Al) detection has generated interest in water-based detector technologies. AI is done using external radiation sources to induce fission and to detect, ...

  2. LANL | Physics | Active Interrogation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Division activities in standoff active-interrogation for detecting terrorist nuclear devices, 2011 Detonation of a terrorist nuclear device in a major city would have...

  3. Quantitative Assessment of Detection Frequency for the INL Ambient Air Monitoring Network

    SciTech Connect (OSTI)

    A. Jeffrey Sondrup; Arthur S. Rood

    2014-11-01T23:59:59.000Z

    A quantitative assessment of the Idaho National Laboratory (INL) air monitoring network was performed using frequency of detection as the performance metric. The INL air monitoring network consists of 37 low-volume air samplers in 31 different locations. Twenty of the samplers are located on INL (onsite) and 17 are located off INL (offsite). Detection frequencies were calculated using both BEA and ESER laboratory minimum detectable activity (MDA) levels. The CALPUFF Lagrangian puff dispersion model, coupled with 1 year of meteorological data, was used to calculate time-integrated concentrations at sampler locations for a 1-hour release of unit activity (1 Ci) for every hour of the year. The unit-activity time-integrated concentration (TICu) values were calculated at all samplers for releases from eight INL facilities. The TICu values were then scaled and integrated for a given release quantity and release duration. All facilities modeled a ground-level release emanating either from the center of the facility or at a point where significant emissions are possible. In addition to ground-level releases, three existing stacks at the Advanced Test Reactor Complex, Idaho Nuclear Technology and Engineering Center, and Material and Fuels Complex were also modeled. Meteorological data from the 35 stations comprising the INL Mesonet network, data from the Idaho Falls Regional airport, upper air data from the Boise airport, and three-dimensional gridded data from the weather research forecasting model were used for modeling. Three representative radionuclides identified as key radionuclides in INL’s annual National Emission Standards for Hazardous Air Pollutants evaluations were considered for the frequency of detection analysis: Cs-137 (beta-gamma emitter), Pu-239 (alpha emitter), and Sr-90 (beta emitter). Source-specific release quantities were calculated for each radionuclide, such that the maximum inhalation dose at any publicly accessible sampler or the National Emission Standards for Hazardous Air Pollutants maximum exposed individual location (i.e., Frenchman’s Cabin) was no more than 0.1 mrem yr–1 (i.e., 1% of the 10 mrem yr–1 standard). Detection frequencies were calculated separately for the onsite and offsite monitoring network. As expected, detection frequencies were generally less for the offsite sampling network compared to the onsite network. Overall, the monitoring network is very effective at detecting the potential releases of Cs-137 or Sr-90 from all sources/facilities using either the ESER or BEA MDAs. The network was less effective at detecting releases of Pu-239. Maximum detection frequencies for Pu-239 using ESER MDAs ranged from 27.4 to 100% for onsite samplers and 3 to 80% for offsite samplers. Using BEA MDAs, the maximum detection frequencies for Pu-239 ranged from 2.1 to 100% for onsite samplers and 0 to 5.9% for offsite samplers. The only release that was not detected by any of the samplers under any conditions was a release of Pu-239 from the Idaho Nuclear Technology and Engineering Center main stack (CPP-708). The methodology described in this report could be used to improve sampler placement and detection frequency, provided clear performance objectives are defined.

  4. Progress Report on the LTS/UMIACS Contract RFP:MDA904-02-R-0151 SOW: R4-02-0001.1

    E-Print Network [OSTI]

    Gruner, Daniel S.

    system gives the traffic profile from different vantage points and the detection system correlates these traffic profiles to single out DoS attacks originating within the AS. We have used a packet level the traffic mapping (load balancing) problem. Given a certain source-destination traffic matrix, we

  5. Nucleic acid detection kits

    DOE Patents [OSTI]

    Hall, Jeff G.; Lyamichev, Victor I.; Mast, Andrea L.; Brow, Mary Ann; Kwiatkowski, Robert W.; Vavra, Stephanie H.

    2005-03-29T23:59:59.000Z

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample.

  6. Solar system fault detection

    DOE Patents [OSTI]

    Farrington, R.B.; Pruett, J.C. Jr.

    1984-05-14T23:59:59.000Z

    A fault detecting apparatus and method are provided for use with an active solar system. The apparatus provides an indication as to whether one or more predetermined faults have occurred in the solar system. The apparatus includes a plurality of sensors, each sensor being used in determining whether a predetermined condition is present. The outputs of the sensors are combined in a pre-established manner in accordance with the kind of predetermined faults to be detected. Indicators communicate with the outputs generated by combining the sensor outputs to give the user of the solar system and the apparatus an indication as to whether a predetermined fault has occurred. Upon detection and indication of any predetermined fault, the user can take appropriate corrective action so that the overall reliability and efficiency of the active solar system are increased.

  7. Detection device for hazardous materials

    DOE Patents [OSTI]

    Partin, Judy K.; Grey, Alan E.

    1994-04-05T23:59:59.000Z

    A detection device that is activated by the interaction of a hazardous chcal with a coating interactive with said chemical on an optical fiber thereby reducing the amount of light passing through the fiber to a light detector. A combination of optical filters separates the light into a signal beam and a reference beam which after detection, appropriate amplification, and comparison with preset internal signals, activates an alarm means if a predetermined level of contaminant is observed.

  8. Detection device for hazardous materials

    DOE Patents [OSTI]

    Partin, Judy K. (Idaho Falls, ID); Grey, Alan E. (Idaho Falls, ID)

    1994-01-01T23:59:59.000Z

    A detection device that is activated by the interaction of a hazardous chcal with a coating interactive with said chemical on an optical fiber thereby reducing the amount of light passing through the fiber to a light detector. A combination of optical filters separates the light into a signal beam and a reference beam which after detection, appropriate amplification, and comparison with preset internal signals, activates an alarm means if a predetermined level of contaminant is observed.

  9. MDA0106-Revised for SFAS 133.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron 9November 6, In this3, BPA earned net3rd Quarter

  10. Fingerprint detection

    DOE Patents [OSTI]

    Saunders, George C. (Rt. 1, Box 428B, Espanola, NM 87532)

    1992-01-01T23:59:59.000Z

    A method for detection and visualization of latent fingerprints is provided and includes contacting a substrate containing a latent print thereon with a colloidal metal composition for time sufficient to allow reaction of said colloidal metal composition with said latent print, and preserving or recording the observable print. Further, the method for detection and visualization of latent fingerprints can include contacting the metal composition-latent print reaction product with a secondary metal-containing solution for time sufficient to allow precipitation of said secondary metal thereby enhancing the visibility of the latent print, and preserving or recording the observable print.

  11. Detection device

    DOE Patents [OSTI]

    Smith, J.E.

    1981-02-27T23:59:59.000Z

    The present invention is directed to a detection device comprising: (1) an entrance chamber; (2) a central chamber; and (3) an exit chamber. The central chamber includes an ionizing gas, anode, and means for connecting the anode with an external power supply and pulse counter.

  12. The vitamin E analog alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    cell lines [33] and human HER2/neu positive (MDA-MB-453) andHER2/neu nega- tive (MDA-MB-231) breast cancer cell linesInvitrogen, Carlsbad, CA). The MDA-MB- 231 and MDA-MB-453

  13. Energy Detectives (3 Activities) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny:RevisedAdvisoryStandard |in STEMEnergy CleanEnergyDepartmentEnergy

  14. Arsenic activation neutron detector

    DOE Patents [OSTI]

    Jacobs, E.L.

    1980-01-28T23:59:59.000Z

    A detector of bursts of neutrons from a deuterium-deuteron reaction includes a quantity of arsenic adjacent a gamma detector such as a scintillator and photomultiplier tube. The arsenic is activated by the 2.5-MeV neutrons to release gamma radiation which is detected to give a quantitative representation of detected neutrons.

  15. Nucleic acid detection compositions

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor I. (Madison, WI); Brow, Mary Ann (Madison, WI); Dahlberg, James L. (Madison, WI)

    2008-08-05T23:59:59.000Z

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  16. Nucleic acid detection assays

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann; Dahlberg, James E.

    2005-04-05T23:59:59.000Z

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  17. Intrusion detection sensor testing tools

    SciTech Connect (OSTI)

    Hayward, D.R.

    1994-08-01T23:59:59.000Z

    Intrusion detection sensors must be frequently tested to verify that they are operational, and they must be periodically tested to verify that they are functioning at required performance levels. Concerns involving this testing can include: The significant amount of manpower required, inconsistent results due to variability in methods and personnel, exposure of personnel to hazardous environments, and difficulty in obtaining access to the areas containing some of the intrusion sensors. To address these concerns, the Department of Energy directed Sandia National Labs. to develop intrusion detection sensor testing tools. Over the past two years Sandia has developed several sensor testing tool prototypes. This paper describes the evolution of an exterior intrusion detection sensor tester and automatic data logger, and also describes various interior intrusion detection sensor test fixtures that can be remotely activated to simulate an intruder.

  18. EEG-based Drowsiness Detection using Support Vector Machine

    E-Print Network [OSTI]

    Yu, Shaoda

    2014-08-07T23:59:59.000Z

    respectively, XA and XT be the EEG spectra in the alpha and theta frequency bands respectively, at some time. The MD for the alpha and theta bands can be calculated by the following: MDA(XA) = ?[(𝑋𝐴 ? µ) 𝑇(?2)?1(𝑋𝐴 ? µ)] (1) MDT... by taking a linear combination of MDA and MDT resulting in: MDC =𝛼 ×𝑀𝐷𝐴 + (1? 𝛼) ×𝑀𝐷𝑇, 0 ? ? ? 1 (3) 5 MDC can be viewed as a combined indicator of drowsiness and the constant ? can be tuned to be more sensitive to MDA or MDT, depending...

  19. Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer

    E-Print Network [OSTI]

    Purcell, James W

    2011-01-01T23:59:59.000Z

    apoptotic markers in the MDA-MB-468 model than in the lessmodels, except BT474 and MDA-MB-468 which were established50 for ispinesib of 45nM) and MDA-MB-468, a basal A triple

  20. Innate immune response to rotavirus infection is differentially modulated by MAVS and TLR3 signaling

    E-Print Network [OSTI]

    Wang, Michael Raymond

    2012-01-01T23:59:59.000Z

    associated protein 5 (Mda-5) receptors detect dsRNA in theto harbor both TLR3 and RIG/Mda-5 dsRNA signaling pathways.associated gene 5 (Mda-5), are two cytoplasmic RIG-I-like

  1. Effect of arthroscopic cartilage defect repair with bone marrow derived cells on the lubricant properties of synovial fluid :

    E-Print Network [OSTI]

    Grissom, Murray J.

    2011-01-01T23:59:59.000Z

    0.25 MDa ranges. NL equine SF (eSF), between 2-3 MDa, but the method of high-upper detection limit of 3 MDa [96]. Studies on human SF (

  2. Detecting Botnets Through Log Correlation

    E-Print Network [OSTI]

    Al-Hammadi, Yousof

    2010-01-01T23:59:59.000Z

    Botnets, which consist of thousands of compromised machines, can cause significant threats to other systems by launching Distributed Denial of Service (SSoS) attacks, keylogging, and backdoors. In response to these threats, new effective techniques are needed to detect the presence of botnets. In this paper, we have used an interception technique to monitor Windows Application Programming Interface (API) functions calls made by communication applications and store these calls with their arguments in log files. Our algorithm detects botnets based on monitoring abnormal activity by correlating the changes in log file sizes from different hosts.

  3. A Simple Technique for Islanding Detection with Negligible Nondetection Zone

    E-Print Network [OSTI]

    Kirtley Jr, James L.

    Although active islanding detection techniques have smaller nondetection zones than passive techniques, active methods could degrade the system power quality and are not as simple and easy to implement as passive methods. ...

  4. 2001 ,7 (4) :348 354 Chin J Appl Environ Biol = ISSN 1006 -687X 2001208225

    E-Print Network [OSTI]

    ,--¨¶"´¶~ SODˇ˘ POD " CAT »--... MDA ",--¨´ ,¸Ż--¨ż¶¨"--¨°­...~... ,,--¨OE¶~ SOD »--^,·,--¨ OE ,MDA " ˇˇ The effects of endophyte infection on the activities of SOD , POD and CAT , as well as on MDA contents in L

  5. Advancing Explosives Detection Capabilities: Vapor Detection

    ScienceCinema (OSTI)

    Atkinson, David

    2014-07-24T23:59:59.000Z

    A new, PNNL-developed method provides direct, real-time detection of trace amounts of explosives such as RDX, PETN and C-4. The method selectively ionizes a sample before passing the sample through a mass spectrometer to detect explosive vapors. The method could be used at airports to improve aviation security.

  6. Revolution in Detection Affairs

    SciTech Connect (OSTI)

    Stern W.

    2013-11-02T23:59:59.000Z

    The detection of nuclear or radioactive materials for homeland or national security purposes is inherently difficult. This is one reason detection efforts must be seen as just one part of an overall nuclear defense strategy which includes, inter alia, material security, detection, interdiction, consequence management and recovery. Nevertheless, one could argue that there has been a revolution in detection affairs in the past several decades as the innovative application of new technology has changed the character and conduct of detection operations. This revolution will likely be most effectively reinforced in the coming decades with the networking of detectors and innovative application of anomaly detection algorithms.

  7. The detection of signals buried in noise

    E-Print Network [OSTI]

    Bergamaschi, Luigi; Giordani, Laura; Mana, Giovanni; Oddone, Massimo

    2013-01-01T23:59:59.000Z

    This paper examines signal detection in the presence of noise, with a particular emphasis to the nuclear activation analysis. The problem is to decide what between the signal-plus-background and no-signal hypotheses fits better the data and to quantify the relevant signal amplitude or detection limit. Our solution is based on the use of Bayesian inferences to test the different hypotheses.

  8. Interior intrusion detection systems

    SciTech Connect (OSTI)

    Rodriguez, J.R.; Matter, J.C. (Sandia National Labs., Albuquerque, NM (United States)); Dry, B. (BE, Inc., Barnwell, SC (United States))

    1991-10-01T23:59:59.000Z

    The purpose of this NUREG is to present technical information that should be useful to NRC licensees in designing interior intrusion detection systems. Interior intrusion sensors are discussed according to their primary application: boundary-penetration detection, volumetric detection, and point protection. Information necessary for implementation of an effective interior intrusion detection system is presented, including principles of operation, performance characteristics and guidelines for design, procurement, installation, testing, and maintenance. A glossary of sensor data terms is included. 36 figs., 6 tabs.

  9. Technologies for detection of nuclear materials

    SciTech Connect (OSTI)

    DeVolpi, A.

    1996-03-30T23:59:59.000Z

    Detection of smuggled nuclear materials at transit points requires monitoring unknown samples in large closed packages. This review contends that high-confidence nuclear-material detection requires induced fission as the primary mechanism, with passive radiation screening in a complementary role. With the right equipment, even small quantities of nuclear materials are detectable with a high probability at transit points. The equipment could also be linked synergistically with detectors of other contrabond. For screening postal mail and packages, passive monitors are probably more cost-effective. When a suspicious item is detected, a single active probe could then be used. Until active systems become mass produced, this two-stage screening/interrogation role for active/passive equipment is more economic for cargo at border crossings. For widespread monitoring of nuclear smuggling, it will probably be necessary to develop a system for simultaneously detecting most categories of contraband, including explosives and illicit drugs. With control of nuclear materials at known storage sites being the first line of defense, detection capabilities at international borders could establish a viable second line of defense against smuggling.

  10. Anonym activities: white-and blackhat applications

    E-Print Network [OSTI]

    Jelasity, Márk

    with ISP-s: traffic filtering, sending and detecting probe packets with an intrusion detection system (IDS blackhat ­ avoid the detection of criminal activity ­ hide crucial infrastructure such as "mothership" servers, monitoring and control servers, etc whitehat ­ protect privacy ­ fight censorship #12;3 Example

  11. Ascofuranone suppresses EGF-induced HIF-1? protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells

    SciTech Connect (OSTI)

    Jeong, Yun-Jeong; Cho, Hyun-Ji [Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu 705-718 (Korea, Republic of); Magae, Junji [Magae Bioscience Institute, 49-4 Fujimidai, Tsukuba 300-1263 (Japan); Lee, In-Kyu [Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721 (Korea, Republic of); Park, Keun-Gyu, E-mail: kpark@knu.ac.kr [Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721 (Korea, Republic of); Chang, Young-Chae, E-mail: ycchang@cu.ac.kr [Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu 705-718 (Korea, Republic of)

    2013-12-15T23:59:59.000Z

    Hypoxia-inducible factor (HIF)-1 plays an important role in tumor progression, angiogenesis and metastasis. In this study, we investigated the potential molecular mechanisms underlying the anti-angiogenic effect of ascofuranone, an isoprenoid antibiotic from Ascochyta viciae, in epidermal growth factor (EGF)-1 responsive human breast cancer cells. Ascofuranone significantly and selectively suppressed EGF-induced HIF-1? protein accumulation, whereas it did not affect the expression of HIF-1?. Furthermore, ascofuranone inhibited the transcriptional activation of vascular endothelial growth factor (VEGF) by reducing protein HIF-1?. Mechanistically, we found that the inhibitory effects of ascofuranone on HIF-1? protein expression are associated with the inhibition of synthesis HIF-1? through an EGF-dependent mechanism. In addition, ascofuranone suppressed EGF-induced phosphorylation of Akt/mTOR/p70S6 kinase, but the phosphorylation of ERK/JNK/p38 kinase was not affected by ascofuranone. These results suggest that ascofuranone suppresses EGF-induced HIF-1? protein translation through the inhibition of Akt/mTOR/p70S6 kinase signaling pathways and plays a novel role in the anti-angiogenic action. - Highlights: • Inhibitory effect of ascofuranone on HIF-1? expression is EGF-specific regulation. • Ascofuranone decreases HIF-1? protein synthesis through Akt/mTOR pathways. • Ascofuranone suppresses EGF-induced VEGF production and tumor angiogenesis.

  12. Performance Evaluation of DCA and SRC on a Single Bot Detection

    E-Print Network [OSTI]

    Aickelin, Uwe

    a better performance in detecting malicious activities. Keywords: Security, Intrusion Detection, Botnet/bot techniques use different types of signatures-based detection by analysing network traffic in order to detect or encrypting the bot's traffic when communicating with the attacker. In addition, a bot can connect to non

  13. Array for detecting microbes

    DOE Patents [OSTI]

    Andersen, Gary L.; DeSantis, Todd D.

    2014-07-08T23:59:59.000Z

    The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level.

  14. Detecting Illicit Nuclear Materials

    SciTech Connect (OSTI)

    Kouzes, Richard T.

    2005-09-01T23:59:59.000Z

    The threat that weapons of mass destruction might enter the United States has led to a number of efforts for the detection and interdiction of nuclear, radiological, chemical, and biological weapons at our borders. There have been multiple deployments of instrumentation to detect radiation signatures to interdict radiological material, including weapons and weapons material worldwide.

  15. Detecting Illicit Radioactive Sources

    SciTech Connect (OSTI)

    McDonald, Joseph C.; Coursey, Bert; Carter, Michael

    2004-11-01T23:59:59.000Z

    Specialized instruments have been developed to detect the presence of illicit radioactive sources that may be used by terrorists in radiation dispersal devices, so-called ''dirty bombs'' or improvised nuclear devices. This article discusses developments in devices to detect and measure radiation.

  16. Lean blowoff detection sensor

    SciTech Connect (OSTI)

    Thornton, Jimmy (Morgantown, WV); Straub, Douglas L. (Morgantown, WV); Chorpening, Benjamin T. (Morgantown, WV); Huckaby, David (Morgantown, WV)

    2007-04-03T23:59:59.000Z

    Apparatus and method for detecting incipient lean blowoff conditions in a lean premixed combustion nozzle of a gas turbine. A sensor near the flame detects the concentration of hydrocarbon ions and/or electrons produced by combustion and the concentration monitored as a function of time are used to indicate incipient lean blowoff conditions.

  17. Passive Neutron Detection for Interdiction of Nuclear Material at Borders

    SciTech Connect (OSTI)

    Kouzes, Richard T.; Siciliano, Edward R.; Ely, James H.; Keller, Paul E.; McConn, Ronald J.

    2008-01-11T23:59:59.000Z

    Radiation portal monitor systems based upon polyvinyl toluene scintillator gamma-ray detectors and pressurized 3He-based neutron detector tubes have been deployed to detect illicit trafficking in radioactive materials at international border crossings. This paper reviews the neutron detection requirements and capabilities of passive, as opposed to active interrogation, detection systems used for screening of high-volume commerce for illicit sources of radiation at international border crossings.

  18. Current Trends in Gamma Ray Detection for Radiological Emergency Response

    SciTech Connect (OSTI)

    Mukhopadhyay, S., Guss, P., Maurer, R.

    2011-08-18T23:59:59.000Z

    Passive and active detection of gamma rays from shielded radioactive materials, including special nuclear materials, is an important task for any radiological emergency response organization. This article reports on the current trends and status of gamma radiation detection objectives and measurement techniques as applied to nonproliferation and radiological emergencies.

  19. Insider Threat Detection using Stream Mining and Graph Mining

    E-Print Network [OSTI]

    Hamlen, Kevin W.

    Insider Threat Detection using Stream Mining and Graph Mining Pallabi Parveen, Jonathan Evans threats who attempt to conceal their activities by varying their behaviors over time. This paper applies of insider threat detection, demonstrating that the ensemble-based approach is significantly more effective

  20. Leak detection aid

    DOE Patents [OSTI]

    Steeper, Timothy J. (Graniteville, SC)

    1989-01-01T23:59:59.000Z

    A leak detection apparatus and method for detecting leaks across an O-ring sealing a flanged surface to a mating surface is an improvement in a flanged surface comprising a shallow groove following O-ring in communication with an entrance and exit port intersecting the shallow groove for injecting and withdrawing, respectively, a leak detection fluid, such as helium. A small quantity of helium injected into the entrance port will flow to the shallow groove, past the O-ring and to the exit port.

  1. Leak detection aid

    DOE Patents [OSTI]

    Steeper, T.J.

    1989-12-26T23:59:59.000Z

    A leak detection apparatus and method for detecting leaks across an O-ring sealing a flanged surface to a mating surface is an improvement in a flanged surface comprising a shallow groove following O-ring in communication with an entrance and exit port intersecting the shallow groove for injecting and withdrawing, respectively, a leak detection fluid, such as helium. A small quantity of helium injected into the entrance port will flow to the shallow groove, past the O-ring and to the exit port. 2 figs.

  2. Termination Detection of Local Computations

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Termination Detection of Local Computations Emmanuel Godard1 , Yves M´etivier2 and Gerard Tel3 1 is glob- ally finished. This paper investigates the problem of the detection of the termination of local computations. We define four types of termination detection: no detection, detection of the local termination

  3. Review by : Haris Volos Paper : Random Early Detection Gateways for Gongestion Avoidance

    E-Print Network [OSTI]

    Akella, Aditya

    Review by : Haris Volos Paper : Random Early Detection Gateways for Gongestion Avoidance Authors : Sally Floyd and Van Jacobson The paper presents an active queue management technique of preventing

  4. Detection of counterfeit currency

    DOE Patents [OSTI]

    Burns, Donald A. (Los Alamos, NM)

    1998-01-01T23:59:59.000Z

    A method of detecting counterfeit currency by contacting the currency to be tested with near infrared beams in the spectrum below 1250 namometers, measuring reflectance of the near infrared beams and comparing the reflectance values with those from genuine currency.

  5. Explosive Detection Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2000-10-26T23:59:59.000Z

    To standardize and accelerate implementation of the Department of Energy (DOE) explosive detection program. DOE N 251.40, dated 5/3/01, extends this directive until 12/31/01.

  6. Bolt failure detection

    DOE Patents [OSTI]

    Sutton, Jr., Harry G. (Pittsburgh, PA)

    1984-01-01T23:59:59.000Z

    Bolts of a liquid metal fast breeder reactor, each bolt provided with an internal chamber filled with a specific, unique radioactive tag gas. Detection of the tag gas is indicative of a crack in an identifiable bolt.

  7. Idaho Explosive Detection System

    ScienceCinema (OSTI)

    Klinger, Jeff

    2013-05-28T23:59:59.000Z

    Learn how INL researchers are making the world safer by developing an explosives detection system that can inspect cargo. For more information about INL security research, visit http://www.facebook.com/idahonationallaboratory

  8. Automated pavement crack detection

    E-Print Network [OSTI]

    Rao, Ashok Madhava

    1991-01-01T23:59:59.000Z

    : Electrical Engineering AUTOMATED PAVEMENT CRACK DETECTION A Thesis by ASHOK MADHAVA RAO Approved as to style and content by . c Norman C. Grisw d (Chair of Committ ) Nasser Kehtarnavaz (Member) g, J~, Karan Watson Robert L. Lytt (Member) Jo W.... Howze (Head of Department) December 1991 111 ABSTRACT Automated Pavement Crack Detection. (December 1991) Ashok Madhava, Rao, B. E. , Mysore University Chair of Advisory Committee: Norman. C. Griswold Due to load, environmental and structural...

  9. Improving airport explosives detection

    SciTech Connect (OSTI)

    Krause, C.

    1990-01-01T23:59:59.000Z

    ORNL has developed the technology to detect hidden explosives in luggage using X ray and neutron detection devices. The Federal Aviation Administration has ordered the airlines to buy and install Thermal Neutron Analysis (TNA) units. The combined pulsed-neutron and X-ray interrogation inspection (CPNX) system developed at ORNL uses less radioactive materials as well as being more sensitive to weapons, electronic devices and plastic explosives.

  10. UV Decontamination of MDA Reagents for Single Cell Genomics

    E-Print Network [OSTI]

    Lee, Janey

    2011-01-01T23:59:59.000Z

    Reagents for Single Cell Genomics Janey Lee 1* , Damon TigheReagents for Single Cell Genomics Janey Lee 1 , Damon TigheAbstract Single cell genomics, the amplification and

  11. Engineering Runtime Requirements-Monitoring Systems using MDA Technologies

    E-Print Network [OSTI]

    Emmerich, Wolfgang

    Emmerich Dept. of Computer Science, University College London Gower St, London, WC1E 6BT, UK {j.skene|w.emmerich

  12. MDA- Energy Efficiency Revolving Loan Program | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy ChinaofSchaeferApril 1, 1999InspectionsAnnualTheEnergia287-5834July 16,MARVINF 742

  13. Microsoft Word - 3rd Qtr - MDA.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHighandSWPA / SPRA / USACE SWPAURTeC: 215362227/15/13

  14. america fy08 activities: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in North America from long-term records of the advanced very high resolution radiometer Geosciences Websites Summary: Interannual changes of active fire detectability in...

  15. active cavity radiometer: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in North America from long-term records of the advanced very high resolution radiometer Geosciences Websites Summary: Interannual changes of active fire detectability in...

  16. Scintillation Properties of Eu2+-Activated Barium Fluoroiodide

    E-Print Network [OSTI]

    Gundiah, Gautam

    2011-01-01T23:59:59.000Z

    2000. R. Hofstandter, “Europium activated strontium iodidebarium fluoroiodide, BaFI, europium, gamma-ray detection,transferred to the dopant europium ions. The optimal dopant

  17. AIDE - Advanced Intrusion Detection Environment

    SciTech Connect (OSTI)

    Smith, Cathy L.

    2013-04-28T23:59:59.000Z

    Would you like to know when someone has dropped an undesirable executable binary on our system? What about something less malicious such as a software installation by a user? What about the user who decides to install a newer version of mod_perl or PHP on your web server without letting you know beforehand? Or even something as simple as when an undocumented config file change is made by another member of the admin group? Do you even want to know about all the changes that happen on a daily basis on your server? The purpose of an intrusion detection system (IDS) is to detect unauthorized, possibly malicious activity. The purpose of a host-based IDS, or file integrity checker, is check for unauthorized changes to key system files, binaries, libraries, and directories on the system. AIDE is an Open Source file and directory integrity checker. AIDE will let you know when a file or directory has been added, deleted, modified. It is included with the Red Hat Enterprise 6. It is available for other Linux distros. This is a case study describing the process of configuring AIDE on an out of the box RHEL6 installation. Its goal is to illustrate the thinking and the process by which a useful AIDE configuration is built.

  18. Distributed Versioning Model for MOF* Petr Hntynka1

    E-Print Network [OSTI]

    activities of OMG: It is addressed in the Model-Driven Architecture (MDA), namely in the Meta Object Facility (MOF), one of the tools MDA provides for developers. 1.1 MDA Model-Driven Architecture [16 of MDA is to separate the functional specification of a designed system and the implementation

  19. Bursts detected and NOT detected by EGRET imaging spark chambers

    SciTech Connect (OSTI)

    Dingus, Brenda L. [University of Utah, Salt Lake City, Utah 84112 (United States); Catelli, Jennifer R. [University of Maryland, College Park, Maryland 20742 (United States); NASA/GSFC, Greenbelt, Maryland 20771 (United States); Schneid, E. J. [Northrop-Grummann, MS A01-26, Bethpage, New York 11714 (United States)

    1998-05-16T23:59:59.000Z

    EGRET has detected the highest energy emission from gamma-ray bursts. Only a few bursts have been detected either coincident or just following the BATSE detected emission. These bursts are among the brightest bursts detected by BATSE. The EGRET fluxes, including upper limits, are consistent with extrapolations for all the burst spectra measured with Comptel.

  20. Error detection method

    SciTech Connect (OSTI)

    Olson, Eric J.

    2013-06-11T23:59:59.000Z

    An apparatus, program product, and method that run an algorithm on a hardware based processor, generate a hardware error as a result of running the algorithm, generate an algorithm output for the algorithm, compare the algorithm output to another output for the algorithm, and detect the hardware error from the comparison. The algorithm is designed to cause the hardware based processor to heat to a degree that increases the likelihood of hardware errors to manifest, and the hardware error is observable in the algorithm output. As such, electronic components may be sufficiently heated and/or sufficiently stressed to create better conditions for generating hardware errors, and the output of the algorithm may be compared at the end of the run to detect a hardware error that occurred anywhere during the run that may otherwise not be detected by traditional methodologies (e.g., due to cooling, insufficient heat and/or stress, etc.).

  1. Composition for detecting uranyl

    DOE Patents [OSTI]

    Baylor, L.C.; Stephens, S.M.

    1994-01-01T23:59:59.000Z

    The present invention relates to an indicator composition for use in spectrophotometric detection of a substance in a solution, and a method for making the composition. Useful indicators are sensitive to the particular substance being measured, but are unaffected by the fluid and other chemical species that may be present in the fluid. Optical indicators are used to measure the uranium concentration of process solutions in facilities for extracting uranium from ores, production of nuclear fuels, and reprocessing of irradiated fuels. The composition comprises an organohalide covalently bonded to an indicator for the substance, in such a manner that the product is itself an indicator that provides increased spectral resolution for detecting the substance. The indicator is preferably arsenazo III and the organohalide is preferably cyanuric chloride. These form a composition that is ideally suited for detecting uranyl.

  2. Detection of solar events

    DOE Patents [OSTI]

    Fischbach, Ephraim; Jenkins, Jere

    2013-08-27T23:59:59.000Z

    A flux detection apparatus can include a radioactive sample having a decay rate capable of changing in response to interaction with a first particle or a field, and a detector associated with the radioactive sample. The detector is responsive to a second particle or radiation formed by decay of the radioactive sample. The rate of decay of the radioactive sample can be correlated to flux of the first particle or the field. Detection of the first particle or the field can provide an early warning for an impending solar event.

  3. Detection of neutrinos

    DOE Patents [OSTI]

    Fischbach, Ephraim; Jenkins, Jere

    2014-02-04T23:59:59.000Z

    A flux detection apparatus can include a radioactive sample having a decay rate capable of changing in response to interaction with a first particle or a field, and a detector associated with the radioactive sample. The detector is responsive to a second particle or radiation formed by decay of the radioactive sample. The rate of decay of the radioactive sample can be correlated to flux of the first particle or the field. Detection of the first particle or the field can provide an early warning for an impending solar event.

  4. Relating to ion detection

    DOE Patents [OSTI]

    Orr, Christopher Henry (Calderbridge, GB); Luff, Craig Janson (Calderbridge, GB); Dockray, Thomas (Calderbridge, GB); Macarthur, Duncan Whittemore (Los Alamos, NM)

    2001-01-01T23:59:59.000Z

    The apparatus and method provide a technique for improving detection of alpha and/or beta emitting sources on items or in locations using indirect means. The emission forms generate ions in a medium surrounding the item or location and the medium is then moved to a detecting location where the ions are discharged to give a measure of the emission levels. To increase the level of ions generated and render the system particularly applicable for narrow pipes and other forms of conduits, the medium pressure is increased above atmospheric pressure. STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT

  5. Liquid detection circuit

    DOE Patents [OSTI]

    Regan, Thomas O. (North Aurora, IL)

    1987-01-01T23:59:59.000Z

    Herein is a circuit which is capable of detecting the presence of liquids, especially cryogenic liquids, and whose sensor will not overheat in a vacuum. The circuit parameters, however, can be adjusted to work with any liquid over a wide range of temperatures.

  6. Initiative for Explosives Detection

    E-Print Network [OSTI]

    capabilities. Staff at PNNL are developing effective integrated systems for explosives detection, addressing, fundamental science and health. Battelle, based in Columbus, Ohio, has operated PNNL since 1965. PNNL's long. PNNL is located in Richland, Washington. Additional web resources are at: http

  7. Detection of counterfeit currency

    DOE Patents [OSTI]

    Burns, D.A.

    1998-05-26T23:59:59.000Z

    A method is disclosed of detecting counterfeit currency by contacting the currency to be tested with near infrared beams in the spectrum below 1,250 nanometers, measuring reflectance of the near infrared beams and comparing the reflectance values with those from genuine currency. 18 figs.

  8. Face Detection Raghuraman Gopalan

    E-Print Network [OSTI]

    Fisher, Kathleen

    -based Feature invariants Template-based Appearance learning Yang et al., "Face detection survey article", PAMI;Template Matching · Store a template ­ Predefined: edges or regions · Deformable: facial contours (e.g., Snakes) · Hand-coded templates (not learned) · Use correlation to locate faces 6 #12;Appearance

  9. Portable raman explosives detection

    SciTech Connect (OSTI)

    Moore, David Steven [Los Alamos National Laboratory; Scharff, Robert J [Los Alamos National Laboratory

    2008-01-01T23:59:59.000Z

    Recent advances in portable Raman instruments have dramatically increased their application to emergency response and forensics, as well as homeland defense. This paper reviews the relevant attributes and disadvantages of portable Raman spectroscopy, both essentially and instrumentally, to the task of explosives detection in the field.

  10. Radiation detection system

    DOE Patents [OSTI]

    Franks, Larry A. (Santa Barbara, CA); Lutz, Stephen S. (Santa Barbara, CA); Lyons, Peter B. (Los Alamos, NM)

    1981-01-01T23:59:59.000Z

    A radiation detection system including a radiation-to-light converter and fiber optic wave guides to transmit the light to a remote location for processing. The system utilizes fluors particularly developed for use with optical fibers emitting at wavelengths greater than about 500 nm and having decay times less than about 10 ns.

  11. Nitrogen dioxide detection

    DOE Patents [OSTI]

    Sinha, Dipen N. (Los Alamos, NM); Agnew, Stephen F. (Los Alamos, NM); Christensen, William H. (Buena Park, CA)

    1993-01-01T23:59:59.000Z

    Method and apparatus for detecting the presence of gaseous nitrogen dioxide and determining the amount of gas which is present. Though polystyrene is normally an insulator, it becomes electrically conductive in the presence of nitrogen dioxide. Conductance or resistance of a polystyrene sensing element is related to the concentration of nitrogen dioxide at the sensing element.

  12. Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer

    SciTech Connect (OSTI)

    Purcell, James W; Davis, Jefferson; Reddy, Mamatha; Martin, Shamra; Samayoa, Kimberly; Vo, Hung; Thomsen, Karen; Bean, Peter; Kuo, Wen Lin; Ziyad, Safiyyah; Billig, Jessica; Feiler, Heidi S; Gray, Joe W; Wood, Kenneth W; Cases, Sylvaine

    2009-06-10T23:59:59.000Z

    Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein (KSP), a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis. Clinical studies of ispinesib have demonstrated a 9% response rate in patients with locally advanced or metastatic breast cancer, and a favorable safety profile without significant neurotoxicities, gastrointestinal toxicities or hair loss. To better understand the potential of ispinesib in the treatment of breast cancer we explored the activity of ispinesib alone and in combination several therapies approved for the treatment of breast cancer. We measured the ispinesib sensitivity and pharmacodynamic response of breast cancer cell lines representative of various subtypes in vitro and as xenografts in vivo, and tested the ability of ispinesib to enhance the anti-tumor activity of approved therapies. In vitro, ispinesib displayed broad anti-proliferative activity against a panel of 53 breast cell-lines. In vivo, ispinesib produced regressions in each of five breast cancer models, and tumor free survivors in three of these models. The effects of ispinesib treatment on pharmacodynamic markers of mitosis and apoptosis were examined in vitro and in vivo, revealing a greater increase in both mitotic and apoptotic markers in the MDA-MB-468 model than in the less sensitive BT-474 model. In vivo, ispinesib enhanced the anti-tumor activity of trastuzumab, lapatinib, doxorubicin, and capecitabine, and exhibited activity comparable to paclitaxel and ixabepilone. These findings support further clinical exploration of KSP inhibitors for the treatment of breast cancer.

  13. Repair Assessment of Sensor Node Failures for Activity Detection

    E-Print Network [OSTI]

    Stankovic, John A.

    to deter- mine if this fault could have caused errors in the past. This approach significantly decreases) If the accuracy still remains below the specified threshold, maintenance should be performed. We have performed preliminary evaluation using a publicly available dataset [4]. Our results show that our approach

  14. active early detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Comparisons of the X-ray afterglow flux to the optical afterglow flux and prompt gamma-ray fluence is used to quantify the seemingly deficient optical, and in some cases...

  15. Analyzing and Detecting Malicious Activities in Emerging Communication Platforms

    E-Print Network [OSTI]

    Yang, Chao

    2014-06-05T23:59:59.000Z

    . . . . . . . . . . . . . . . . 165 xii 1. INTRODUCTION In the recent years, with the innovation of Online Social Networking (OSN) plat- forms (e.g., Twitter and Facebook) and Smartphone platforms (e.g., Android), many people have changed their lifestyle, from posting their recent... Spam 2009 Twitter spam invades trending topics [81] Phishing 2009 A new phishing scam spreads through direct messages [56] Hosting Botnet 2009 Twitter-based Botnet Command Channel [59] Clickjacking 2010 Facebook clickjacking attack spreads through...

  16. An active oil spill detection digital processing system

    E-Print Network [OSTI]

    Dennard, Robert Marion

    1976-01-01T23:59:59.000Z

    multiple scatter return (denoted by superscript m) . Thus, or hh gi + hh The cross-polarized return (p or P ) consists only of vh hv a multiple scatter term, or = P?i, The development of the single scatter model, which will not be given here...

  17. acoustic detection activities: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - TxSpace Summary: position by locking the window to the carotid pulse and the ECG complex. The windows segmented the heart cycles into diastolic and systolic intervals....

  18. A Multidisciplinary Approach To Detect Active Pathways For Magma Migration

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to:Ezfeedflag JumpID-fTriWildcat 1 WindtheEnergy InformationOf The 28-29 MarchIsland,

  19. Detection of phenols using engineered bacteria

    DOE Patents [OSTI]

    Wise, Arlene A. (Philadelphia, PA); Kuske, Cheryl R. (Los Alamos, NM); Terwilliger, Thomas C. (Santa Fe, NM)

    2007-12-04T23:59:59.000Z

    Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate transcriptional activator senses the inducing chemical. Creation of bacterial biosensors is currently restricted by limited knowledge of the genetic systems of bacteria that catabolize xenobiotics. By using mutagenic PCR to change the chemical specificity of the Pseudomonas species CF600 DmpR protein, the potential for engineering novel biosensors for detection of phenols has been demonstrated. DmpR, a well-characterized transcriptional activator of the P. CF600's dmp operon mediates growth on simple phenols. Transcription from Po, the promoter heading the dmp operon, is activated when the sensor domain of DmpR interacts with phenol and mono-substituted phenols. By altering the sensor domain of the DmpR, a group of DmpR derivatives that activate transcription of a Po-lacZ fusion in response to eight of the EPA's eleven priority pollutant phenols has been created. The assays and the sensor domain mutations that alter the chemical specificity of DmpR is described.

  20. Detection of phenols using engineered bacteria

    DOE Patents [OSTI]

    Wise, Arlene A.; Kuske, Cheryl R.; Terwilliger, Thomas C.

    2004-08-10T23:59:59.000Z

    Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate transcriptional activator senses the inducing chemical. Creation of bacterial biosensors is currently restricted by limited knowledge of the genetic systems of bacteria that catabolize xenobiotics. By using mutagenic PCR to change the chemical specificity of the Pseudomonas species CF600 DmpR protein, the potential for engineering novel biosensors for detection of phenols has been demonstrated. DmpR, a well-characterized transcriptional activator of the P. CF600's dmp operon mediates growth on simple phenols. Transcription from Po, the promoter heading the dmp operon, is activated when the sensor domain of DmpR interacts with phenol and mono-substituted phenols. By altering the sensor domain of the DmpR, a group of DmpR derivatives that activate transcription of a Po-lacZ fusion in response to eight of the EPA's eleven priority pollutant phenols has been created. The assays and the sensor domain mutations that alter the chemical specificity of DmpR is described.

  1. Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and ?-catenin signaling pathway

    SciTech Connect (OSTI)

    Li, Hongzhong; Huang, Jing; Yang, Bing; Xiang, Tingxiu; Yin, Xuedong; Peng, Weiyan; Cheng, Wei [Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing (China); Wan, Jingyuan; Luo, Fuling [Department of Pharmacology, Chongqing Medical University, Chongqing (China); Li, Hongyuan [Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing (China); Ren, Guosheng, E-mail: rgs726@163.com [Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing (China)

    2013-10-01T23:59:59.000Z

    Although mangiferin which is a naturally occurring glucosylxanthone has exhibited promising anticancer activities, the detailed molecular mechanism of mangiferin on cancers still remains enigmatic. In this study, the anticancer activity of mangiferin was evaluated in breast cancer cell line-based in vitro and in vivo models. We showed that mangiferin treatment resulted in decreased cell viability and suppression of metastatic potential in breast cancer cells. Further mechanistic investigation revealed that mangiferin induced decreased matrix metalloproteinase (MMP)-7 and -9, and reversal of epithelial–mesenchymal transition (EMT). Moreover, it was demonstrated that mangiferin significantly inhibited the activation of ?-catenin pathway. Subsequent experiments showed that inhibiting ?-catenin pathway might play a central role in mangiferin-induced anticancer activity through modulation of MMP-7 and -9, and EMT. Consistent with these findings in vitro, the antitumor potential was also verified in mangiferin-treated MDA-MB-231 xenograft mice where significantly decreased tumor volume, weight and proliferation, and increased apoptosis were obtained, with lower expression of MMP-7 and -9, vimentin and active ?-catenin, and higher expression of E-cadherin. Taken together, our study suggests that mangiferin might be used as an effective chemopreventive agent against breast cancer. - Highlights: • Mangiferin inhibits growth and metastatic potential in breast cancer cells. • Mangiferin down-regulates MMP-7 and -9 in breast cancer cells. • Mangiferin induces the reversal of EMT in metastatic breast cancer cells. • Mangiferin inhibits the activation of ?-catenin pathway in breast cancer cells. • Inhibiting ?-catenin is responsible for the antitumor activity of mangiferin.

  2. Cell Phone Detection Techniques

    SciTech Connect (OSTI)

    Pratt, Richard M.; Bunch, Kyle J.; Puzycki, David J.; Slaugh, Ryan W.; Good, Morris S.; McMakin, Douglas L.

    2007-10-01T23:59:59.000Z

    A team composed of Rick Pratt, Dave Puczyki, Kyle Bunch, Ryan Slaugh, Morris Good, and Doug McMakin teamed together to attempt to exploit cellular telephone features and detect if a person was carrying a cellular telephone into a Limited Area. The cell phone’s electromagnetic properties were measured, analyzed, and tested in over 10 different ways to determine if an exploitable signature exists. The method that appears to have the most potential for success without adding an external tag is to measure the RF spectrum, not in the cell phone band, but between 240 and 400MHz. Figures 1- 7 show the detected signal levels from cell phones from three different manufacturers.

  3. Solar neutrino detection

    E-Print Network [OSTI]

    Lino Miramonti

    2009-01-22T23:59:59.000Z

    More than 40 years ago, neutrinos where conceived as a way to test the validity of the solar models which tell us that stars are powered by nuclear fusion reactions. The first measurement of the neutrino flux, in 1968 in the Homestake mine in South Dakota, detected only one third of the expected value, originating what has been known as the Solar Neutrino Problem. Different experiments were built in order to understand the origin of this discrepancy. Now we know that neutrinos undergo oscillation phenomenon changing their nature traveling from the core of the Sun to our detectors. In the work the 40 year long saga of the neutrino detection is presented; from the first proposals to test the solar models to last real time measurements of the low energy part of the neutrino spectrum.

  4. Protein detection system

    DOE Patents [OSTI]

    Fruetel, Julie A. (Livermore, CA); Fiechtner, Gregory J. (Bethesda, MD); Kliner, Dahv A. V. (San Ramon, CA); McIlroy, Andrew (Livermore, CA)

    2009-05-05T23:59:59.000Z

    The present embodiment describes a miniature, microfluidic, absorption-based sensor to detect proteins at sensitivities comparable to LIF but without the need for tagging. This instrument utilizes fiber-based evanescent-field cavity-ringdown spectroscopy, in combination with faceted prism microchannels. The combination of these techniques will increase the effective absorption path length by a factor of 10.sup.3 to 10.sup.4 (to .about.1-m), thereby providing unprecedented sensitivity using direct absorption. The coupling of high-sensitivity absorption with high-performance microfluidic separation will enable real-time sensing of biological agents in aqueous samples (including aerosol collector fluids) and will provide a general method with spectral fingerprint capability for detecting specific bio-agents.

  5. Method for detecting biomolecules

    DOE Patents [OSTI]

    Huo, Qisheng (Albuquerque, NM); Liu, Jun (Albuquerque, NM)

    2008-08-12T23:59:59.000Z

    A method for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode

  6. Aspects of leak detection

    SciTech Connect (OSTI)

    Chivers, T.C. [Berkeley Technology Centre, Glos (United Kingdom)

    1997-04-01T23:59:59.000Z

    A requirement of a Leak before Break safety case is that the leakage from the through wall crack be detected prior to any growth leading to unacceptable failure. This paper sets out to review some recent developments in this field. It does not set out to be a comprehensive guide to all of the methods available. The discussion concentrates on acoustic emission and how the techniques can be qualified and deployed on operational plant.

  7. Detection of pump degradation

    SciTech Connect (OSTI)

    Greene, R.H.; Casada, D.A.; Ayers, C.W. [and others

    1995-08-01T23:59:59.000Z

    This Phase II Nuclear Plant Aging Research study examines the methods of detecting pump degradation that are currently employed in domestic and overseas nuclear facilities. This report evaluates the criteria mandated by required pump testing at U.S. nuclear power plants and compares them to those features characteristic of state-of-the-art diagnostic programs and practices currently implemented by other major industries. Since the working condition of the pump driver is crucial to pump operability, a brief review of new applications of motor diagnostics is provided that highlights recent developments in this technology. The routine collection and analysis of spectral data is superior to all other technologies in its ability to accurately detect numerous types and causes of pump degradation. Existing ASME Code testing criteria do not require the evaluation of pump vibration spectra but instead overall vibration amplitude. The mechanical information discernible from vibration amplitude analysis is limited, and several cases of pump failure were not detected in their early stages by vibration monitoring. Since spectral analysis can provide a wealth of pertinent information concerning the mechanical condition of rotating machinery, its incorporation into ASME testing criteria could merit a relaxation in the monthly-to-quarterly testing schedules that seek to verify and assure pump operability. Pump drivers are not included in the current battery of testing. Operational problems thought to be caused by pump degradation were found to be the result of motor degradation. Recent advances in nonintrusive monitoring techniques have made motor diagnostics a viable technology for assessing motor operability. Motor current/power analysis can detect rotor bar degradation and ascertain ranges of hydraulically unstable operation for a particular pump and motor set. The concept of using motor current or power fluctuations as an indicator of pump hydraulic load stability is presented.

  8. Fraud Detection in Healthcare

    SciTech Connect (OSTI)

    Chandola, Varun [ORNL; Schryver, Jack C [ORNL; Sukumar, Sreenivas R [ORNL

    2015-01-01T23:59:59.000Z

    We discuss the problem of fraud detection in healthcare in this chapter. Given the recent scrutiny of the ineciencies in the US healthcare system, identifying fraud has been on the forefront of the eorts towards reducing the healthcare costs. In this chapter we will focus on understanding the issue of healthcare fraud in detail, and review methods that have been proposed in the literature to combat this issue using data driven approach.

  9. Biomolecular detection device

    DOE Patents [OSTI]

    Huo, Qisheng (Albuquerque, NM); Liu, Jun (Albuquerque, NM)

    2008-10-21T23:59:59.000Z

    A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode.

  10. Detecting the climatic effects of increasing carbon dioxide

    SciTech Connect (OSTI)

    MacCracken, M C; Luther, F M [eds.

    1985-12-01T23:59:59.000Z

    This report documents what is known about detecting the CO2-induced changes in climate, and describes the uncertainties and unknowns associated with this monitoring and analysis effort. The various approaches for detecting CO2-induced climate changes are discussed first, followed by a review of applications of these strategies to the various climatic variables that are expected to be changing. Recommendations are presented for research and analysis activities. Separate abstracts have been prepared for the individual papers. (ACR)

  11. Improved Microseismicity Detection During Newberry EGS Stimulations

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Templeton, Dennise

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  12. Improved Microseismicity Detection During Newberry EGS Stimulations

    SciTech Connect (OSTI)

    Templeton, Dennise

    2013-11-01T23:59:59.000Z

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  13. Improved Microseismicity Detection During Newberry EGS Stimulations

    SciTech Connect (OSTI)

    Templeton, Dennise

    2013-10-01T23:59:59.000Z

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  14. Methods and systems for remote detection of gases

    DOE Patents [OSTI]

    Johnson, Timothy J

    2012-09-18T23:59:59.000Z

    Novel systems and methods for remotely detecting at least one constituent of a gas via infrared detection are provided. A system includes at least one extended source of broadband infrared radiation and a spectrally sensitive receiver positioned remotely from the source. The source and the receiver are oriented such that a surface of the source is in the field of view of the receiver. The source includes a heating component thermally coupled to the surface, and the heating component is configured to heat the surface to a temperature above ambient temperature. The receiver is operable to collect spectral infrared absorption data representative of a gas present between the source and the receiver. The invention advantageously overcomes significant difficulties associated with active infrared detection techniques known in the art, and provides an infrared detection technique with a much greater sensitivity than passive infrared detection techniques known in the art.

  15. Methods and systems for remote detection of gases

    DOE Patents [OSTI]

    Johnson, Timothy J. (Pasco, WA)

    2007-11-27T23:59:59.000Z

    Novel systems and methods for remotely detecting at least one constituent of a gas via infrared detection are provided. A system includes at least one extended source of broadband infrared radiation and a spectrally sensitive receiver positioned remotely from the source. The source and the receiver are oriented such that a surface of the source is in the field of view of the receiver. The source includes a heating component thermally coupled to the surface, and the heating component is configured to heat the surface to a temperature above ambient temperature. The receiver is operable to collect spectral infrared absorption data representative of a gas present between the source and the receiver. The invention advantageously overcomes significant difficulties associated with active infrared detection techniques known in the art, and provides an infrared detection technique with a much greater sensitivity than passive infrared detection techniques known in the art.

  16. Flaw detection and evaluation

    DOE Patents [OSTI]

    Wilks, Robert S. (Plum, PA); Sturges, Jr., Robert H. (Plum, PA)

    1983-01-01T23:59:59.000Z

    The invention provides a method of and apparatus for optically inspecting nuclear fuel pellets for surface flaws. The inspection system includes a prism and lens arrangement for scanning the surface of each pellet as the same is rotated. The resulting scan produces data indicative of the extent and shape of each flaw which is employed to generate a flaw quality index for each detected flaw. The flaw quality indexes from all flaws are summed and compared with an acceptable surface quality index. The result of the comparison is utilized to control the acceptance or rejection of the pellet.

  17. Opaque cloud detection

    DOE Patents [OSTI]

    Roskovensky, John K. (Albuquerque, NM)

    2009-01-20T23:59:59.000Z

    A method of detecting clouds in a digital image comprising, for an area of the digital image, determining a reflectance value in at least three discrete electromagnetic spectrum bands, computing a first ratio of one reflectance value minus another reflectance value and the same two values added together, computing a second ratio of one reflectance value and another reflectance value, choosing one of the reflectance values, and concluding that an opaque cloud exists in the area if the results of each of the two computing steps and the choosing step fall within three corresponding predetermined ranges.

  18. Electrical leakage detection circuit

    DOE Patents [OSTI]

    Wild, Arthur

    2006-09-05T23:59:59.000Z

    A method is provided for detecting electrical leakage between a power supply and a frame of a vehicle or machine. The disclosed method includes coupling a first capacitor between a frame and a first terminal of a power supply for a predetermined period of time. The current flowing between the frame and the first capacitor is limited to a predetermined current limit. It is determined whether the voltage across the first capacitor exceeds a threshold voltage. A first output signal is provided when the voltage across the capacitor exceeds the threshold voltage.

  19. Detection of alpha radiation in a beta radiation field

    DOE Patents [OSTI]

    Mohagheghi, Amir H. (Albuquerque, NM); Reese, Robert P. (Edgewood, NM)

    2001-01-01T23:59:59.000Z

    An apparatus and method for detecting alpha particles in the presence of high activities of beta particles utilizing an alpha spectrometer. The apparatus of the present invention utilizes a magnetic field applied around the sample in an alpha spectrometer to deflect the beta particles from the sample prior to reaching the detector, thus permitting detection of low concentrations of alpha particles. In the method of the invention, the strength of magnetic field required to adequately deflect the beta particles and permit alpha particle detection is given by an algorithm that controls the field strength as a function of sample beta energy and the distance of the sample to the detector.

  20. DCA for Bot Detection

    E-Print Network [OSTI]

    Al-Hammadi, Yousof; Greensmith, Julie

    2010-01-01T23:59:59.000Z

    Ensuring the security of computers is a non-trivial task, with many techniques used by malicious users to compromise these systems. In recent years a new threat has emerged in the form of networks of hijacked zombie machines used to perform complex distributed attacks such as denial of service and to obtain sensitive data such as password information. These zombie machines are said to be infected with a 'bot' - a malicious piece of software which is installed on a host machine and is controlled by a remote attacker, termed the 'botmaster of a botnet'. In this work, we use the biologically inspired Dendritic Cell Algorithm (DCA) to detect the existence of a single bot on a compromised host machine. The DCA is an immune-inspired algorithm based on an abstract model of the behaviour of the dendritic cells of the human body. The basis of anomaly detection performed by the DCA is facilitated using the correlation of behavioural attributes such as keylogging and packet flooding behaviour. The results of the applica...

  1. Documenting Western Burrowing Owl Reproduction and Activity Patterns Using Motion-Activated Cameras

    SciTech Connect (OSTI)

    Hall, Derek B. [NSTec; Greger, Paul D. [NSTec

    2014-08-01T23:59:59.000Z

    We used motion-activated cameras to monitor the reproduction and patterns of activity of the Burrowing Owl (Athene cunicularia) above ground at 45 burrows in south-central Nevada during the breeding seasons of 1999, 2000, 2001, and 2005. The 37 broods, encompassing 180 young, raised over the four years represented an average of 4.9 young per successful breeding pair. Young and adult owls were detected at the burrow entrance at all times of the day and night, but adults were detected more frequently during afternoon/early evening than were young. Motion-activated cameras require less effort to implement than other techniques. Limitations include photographing only a small percentage of owl activity at the burrow; not detecting the actual number of eggs, young, or number fledged; and not being able to track individual owls over time. Further work is also necessary to compare the accuracy of productivity estimates generated from motion-activated cameras with other techniques.

  2. Identifying Activity

    E-Print Network [OSTI]

    Lewis, Adrian S

    2009-01-01T23:59:59.000Z

    Identification of active constraints in constrained optimization is of interest from both practical and theoretical viewpoints, as it holds the promise of reducing an inequality-constrained problem to an equality-constrained problem, in a neighborhood of a solution. We study this issue in the more general setting of composite nonsmooth minimization, in which the objective is a composition of a smooth vector function c with a lower semicontinuous function h, typically nonsmooth but structured. In this setting, the graph of the generalized gradient of h can often be decomposed into a union (nondisjoint) of simpler subsets. "Identification" amounts to deciding which subsets of the graph are "active" in the criticality conditions at a given solution. We give conditions under which any convergent sequence of approximate critical points finitely identifies the activity. Prominent among these properties is a condition akin to the Mangasarian-Fromovitz constraint qualification, which ensures boundedness of the set of...

  3. Detection of gas leakage

    DOE Patents [OSTI]

    Thornberg, Steven (Peralta, NM); Brown, Jason (Albuquerque, NM)

    2012-06-19T23:59:59.000Z

    A method of detecting leaks and measuring volumes as well as an apparatus, the Power-free Pump Module (PPM), that is a self-contained leak test and volume measurement apparatus that requires no external sources of electrical power during leak testing or volume measurement, where the invention is a portable, pneumatically-controlled instrument capable of generating a vacuum, calibrating volumes, and performing quantitative leak tests on a closed test system or device, all without the use of alternating current (AC) power. Capabilities include the ability is to provide a modest vacuum (less than 10 Torr), perform a pressure rise leak test, measure the gas's absolute pressure, and perform volume measurements. All operations are performed through a simple rotary control valve which controls pneumatically-operated manifold valves.

  4. Arc fault detection system

    DOE Patents [OSTI]

    Jha, Kamal N. (Bethel Park, PA)

    1999-01-01T23:59:59.000Z

    An arc fault detection system for use on ungrounded or high-resistance-grounded power distribution systems is provided which can be retrofitted outside electrical switchboard circuits having limited space constraints. The system includes a differential current relay that senses a current differential between current flowing from secondary windings located in a current transformer coupled to a power supply side of a switchboard, and a total current induced in secondary windings coupled to a load side of the switchboard. When such a current differential is experienced, a current travels through a operating coil of the differential current relay, which in turn opens an upstream circuit breaker located between the switchboard and a power supply to remove the supply of power to the switchboard.

  5. Arc fault detection system

    DOE Patents [OSTI]

    Jha, K.N.

    1999-05-18T23:59:59.000Z

    An arc fault detection system for use on ungrounded or high-resistance-grounded power distribution systems is provided which can be retrofitted outside electrical switchboard circuits having limited space constraints. The system includes a differential current relay that senses a current differential between current flowing from secondary windings located in a current transformer coupled to a power supply side of a switchboard, and a total current induced in secondary windings coupled to a load side of the switchboard. When such a current differential is experienced, a current travels through a operating coil of the differential current relay, which in turn opens an upstream circuit breaker located between the switchboard and a power supply to remove the supply of power to the switchboard. 1 fig.

  6. Target detection portal

    DOE Patents [OSTI]

    Linker, Kevin L. (Albuquerque, NM); Brusseau, Charles A. (Tijeras, NM)

    2002-01-01T23:59:59.000Z

    A portal apparatus for screening persons or objects for the presence of trace amounts of target substances such as explosives, narcotics, radioactive materials, and certain chemical materials. The portal apparatus can have a one-sided exhaust for an exhaust stream, an interior wall configuration with a concave-shape across a horizontal cross-section for each of two facing sides to result in improved airflow and reduced washout relative to a configuration with substantially flat parallel sides; air curtains to reduce washout; ionizing sprays to collect particles bound by static forces, as well as gas jet nozzles to dislodge particles bound by adhesion to the screened person or object. The portal apparatus can be included in a detection system with a preconcentrator and a detector.

  7. Waveguide disturbance detection method

    DOE Patents [OSTI]

    Korneev, Valeri A. (Albany, CA); Nihei, Kurt T. (Oakland, CA); Myer, Larry R. (Benicia, CA)

    2000-01-01T23:59:59.000Z

    A method for detection of a disturbance in a waveguide comprising transmitting a wavefield having symmetric and antisymmetric components from a horizontally and/or vertically polarized source and/or pressure source disposed symmetrically with respect to the longitudinal central axis of the waveguide at one end of the waveguide, recording the horizontal and/or vertical component or a pressure of the wavefield with a vertical array of receivers disposed at the opposite end of the waveguide, separating the wavenumber transform of the wavefield into the symmetric and antisymmetric components, integrating the symmetric and antisymmetric components over a broad frequency range, and comparing the magnitude of the symmetric components and the antisymmetric components to an expected magnitude for the symmetric components and the antisymmetric components for a waveguide of uniform thickness and properties thereby determining whether or not a disturbance is present inside the waveguide.

  8. Amplification of Xenon NMR and MRI by remote detection

    SciTech Connect (OSTI)

    Moule, Adam J.; Spence, Megan M.; Han, Song-I.; Seeley, JulietteA.; Pierce, Kimberly L.; Saxena, Sunil; Pines, Alexander

    2003-03-31T23:59:59.000Z

    A novel technique is proposed in which a nuclear magneticresonance (NMR) spectrum or magnetic resonance image (MRI) is encoded andstored as spin polarization and is then moved to a different physicallocation to be detected. Remote detection allows the separateoptimization of the encoding and detection steps, permitting theindependent choice of experimental conditions, and excitation anddetection methodologies. In the first experimental demonstration of thistechnique, we show that NMR signal can be amplified by taking diluted129Xe from a porous sample placed inside a large encoding coil, andconcentrating it into a smaller detection coil. In general, the study ofNMR active molecules at low concentration that have low physical fillingfactor is facilitated by remote detection. In the second experiment, MRIinformation encoded in a very low field magnet (4-7mT) is transferred toa high field magnet (4.2 T) in order to be detected under optimizedconditions. Furthermore, remote detection allows the utilization ofultra-sensitive optical or superconducting detection techniques, whichbroadens the horizon of NMR experimentation.

  9. Activity report

    SciTech Connect (OSTI)

    Yu, S W

    2008-08-11T23:59:59.000Z

    This report is aimed to show the author's activities to support the LDRD. The title is 'Investigation of the Double-C Behavior in the Pu-Ga Time-Temperature-Transformation Diagram' The sections are: (1) Sample Holder Test; (2) Calculation of x-ray diffraction patterns; (3) Literature search and preparing publications; (4) Tasks Required for APS Experiments; and (5) Communications.

  10. Current Trends in Gamma Radiation Detection for Radiological Emergency Response

    SciTech Connect (OSTI)

    Mukhopadhyay, S., Guss, P., Maurer, R.

    2011-09-01T23:59:59.000Z

    Passive and active detection of gamma rays from shielded radioactive materials, including special nuclear materials, is an important task for any radiological emergency response organization. This article reports on the current trends and status of gamma radiation detection objectives and measurement techniques as applied to nonproliferation and radiological emergencies. In recent years, since the establishment of the Domestic Nuclear Detection Office by the Department of Homeland Security, a tremendous amount of progress has been made in detection materials (scintillators, semiconductors), imaging techniques (Compton imaging, use of active masking and hybrid imaging), data acquisition systems with digital signal processing, field programmable gate arrays and embedded isotopic analysis software (viz. gamma detector response and analysis software [GADRAS]1), fast template matching, and data fusion (merging radiological data with geo-referenced maps, digital imagery to provide better situational awareness). In this stride to progress, a significant amount of interdisciplinary research and development has taken place–techniques and spin-offs from medical science (such as x-ray radiography and tomography), materials engineering (systematic planned studies on scintillators to optimize several qualities of a good scintillator, nanoparticle applications, quantum dots, and photonic crystals, just to name a few). No trend analysis of radiation detection systems would be complete without mentioning the unprecedented strategic position taken by the National Nuclear Security Administration (NNSA) to deter, detect, and interdict illicit trafficking in nuclear and other radioactive materials across international borders and through the global maritime transportation–the so-called second line of defense.

  11. Method for detecting an element

    DOE Patents [OSTI]

    Blackwood, Larry G.; Reber, Edward L.; Rohde, Kenneth W.

    2007-02-06T23:59:59.000Z

    A method for detecting an element is disclosed and which includes the steps of providing a gamma-ray spectrum which depicts, at least in part, a test region having boundaries, and which has a small amount of the element to be detected; providing a calculation which detects the small amount of the element to be detected; and providing a moving window and performing the calculation within the moving window, and over a range of possible window boundaries within the test region to determine the location of the optimal test region within the gamma-ray spectrum.

  12. Detecting Internet Worms at Early Stage Shigang Chen Sanjay Ranka

    E-Print Network [OSTI]

    Chen, Shigang

    proposes an Internet-worm early warning system that automatically detects concerted scan activities on the responsiveness of this early warning system. Keywords: Enterprise Security Management, Internet Worm, Early and derives possible signatures of worm attacks. Its goal is to issue warning at the early stage of worm

  13. WHOP: Wormhole Attack Detection Protocol using Hound Packet

    E-Print Network [OSTI]

    Dharmaraja, S.

    WHOP: Wormhole Attack Detection Protocol using Hound Packet Saurabh Gupta Indian Institute infrastructure in ad hoc network makes it vulnerable to various attacks. MANET routing disrupts if participating node do not perform its intended function and start performing malicious activity. A specific attack

  14. The detection of bulk explosives using nuclear-based techniques

    SciTech Connect (OSTI)

    Morgado, R.E.; Gozani, T.; Seher, C.C.

    1988-01-01T23:59:59.000Z

    In 1986 we presented a rationale for the detection of bulk explosives based on nuclear techniques that addressed the requirements of civil aviation security in the airport environment. Since then, efforts have intensified to implement a system based on thermal neutron activation (TNA), with new work developing in fast neutron and energetic photon reactions. In this paper we will describe these techniques and present new results from laboratory and airport testing. Based on preliminary results, we contended in our earlier paper that nuclear-based techniques did provide sufficiently penetrating probes and distinguishable detectable reaction products to achieve the FAA operational goals; new data have supported this contention. The status of nuclear-based techniques for the detection of bulk explosives presently under investigation by the US Federal Aviation Administration (FAA) is reviewed. These include thermal neutron activation (TNA), fast neutron activation (FNA), the associated particle technique, nuclear resonance absorption, and photoneutron activation. The results of comprehensive airport testing of the TNA system performed during 1987-88 are summarized. From a technical point of view, nuclear-based techniques now represent the most comprehensive and feasible approach for meeting the operational criteria of detection, false alarms, and throughput. 9 refs., 5 figs., 2 tabs.

  15. Intrusion Detection, Diagnosis, and Recovery with SelfSecuring Storage

    E-Print Network [OSTI]

    Intrusion Detection, Diagnosis, and Recovery with Self­Securing Storage John Strunk, Garth Goodson Carnegie Mellon University Pittsburgh, 15213 Abstract Self­securing storage turns storage devices active parts of intrusion survival strategy. From behind storage interface (e.g., SCSI CIFS), a self

  16. T Plant secondary containment and leak detection upgrades

    SciTech Connect (OSTI)

    Carlson, T.A.

    1995-10-19T23:59:59.000Z

    The W-259 project will provide upgrades to the 2706-T/TA Facility to comply with Federal and State of Washington environmental regulations for secondary containment and leak detection. The project provides decontamination activities supporting the environmental restoration mission and waste management operations on the Hanford Site.

  17. Detection of nucleic acids by multiple sequential invasive cleavages

    DOE Patents [OSTI]

    Hall, Jeff G; Lyamichev, Victor I; Mast, Andrea L; Brow, Mary Ann D

    2012-10-16T23:59:59.000Z

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of human cytomegalovirus nucleic acid in a sample.

  18. Incipient fire detection system

    DOE Patents [OSTI]

    Brooks, Jr., William K. (Newport News, VA)

    1999-01-01T23:59:59.000Z

    A method and apparatus for an incipient fire detection system that receives gaseous samples and measures the light absorption spectrum of the mixture of gases evolving from heated combustibles includes a detector for receiving gaseous samples and subjecting the samples to spectroscopy and determining wavelengths of absorption of the gaseous samples. The wavelengths of absorption of the gaseous samples are compared to predetermined absorption wavelengths. A warning signal is generated whenever the wavelengths of absorption of the gaseous samples correspond to the predetermined absorption wavelengths. The method includes receiving gaseous samples, subjecting the samples to light spectroscopy, determining wavelengths of absorption of the gaseous samples, comparing the wavelengths of absorption of the gaseous samples to predetermined absorption wavelengths and generating a warning signal whenever the wavelengths of absorption of the gaseous samples correspond to the predetermined absorption wavelengths. In an alternate embodiment, the apparatus includes a series of channels fluidically connected to a plurality of remote locations. A pump is connected to the channels for drawing gaseous samples into the channels. A detector is connected to the channels for receiving the drawn gaseous samples and subjecting the samples to spectroscopy. The wavelengths of absorption are determined and compared to predetermined absorption wavelengths is provided. A warning signal is generated whenever the wavelengths correspond.

  19. Method and apparatus for enhanced detection of toxic agents

    DOE Patents [OSTI]

    Greenbaum, Elias (Knoxville, TN); Rodriguez, Jr., Miguel (Oak Ridge, TN); Wu, Jie Jayne (Knoxville, TN); Qi, Hairong (Knoxville, TN)

    2012-06-12T23:59:59.000Z

    A water quality analyzer for real-time detection according to the invention comprises a biased AC electro-osmosis (ACEO) cell for receiving a fluid to be analyzed having a plurality photosynthetic organisms therein, and concentrating the plurality photosynthetic organisms into at least one concentrated region. A photodetector is provided for obtaining a measured photosynthetic activity of the plurality of photosynthetic organisms in the concentrated region, wherein chemical, biological or radiological agents reduce a nominal photosynthetic activity of the photosynthetic organisms. An electronics package analyzes the measured photosynthetic activity to indicate a presence of the chemical, biological or radiological agents in the fluid.

  20. Supernova Neutrinos Detection On Earth

    E-Print Network [OSTI]

    Xin-Heng Guo; Ming-Yang Huang; Bing-Lin Young

    2009-05-12T23:59:59.000Z

    In this paper, we first discuss the detection of supernova neutrino on Earth. Then we propose a possible method to acquire information about $\\theta_{13}$ smaller than $1.5^\\circ$ by detecting the ratio of the event numbers of different flavor supernova neutrinos. Such an sensitivity cannot yet be achieved by the Daya Bay reactor neutrino experiment.

  1. Bubble Radiation Detection: Current and Future Capability

    SciTech Connect (OSTI)

    AJ Peurrung; RA Craig

    1999-11-15T23:59:59.000Z

    Despite a number of noteworthy achievements in other fields, superheated droplet detectors (SDDs) and bubble chambers (BCs) have not been used for nuclear nonproliferation and arms control. This report examines these two radiation-detection technologies in detail and answers the question of how they can be or should be ''adapted'' for use in national security applications. These technologies involve closely related approaches to radiation detection in which an energetic charged particle deposits sufficient energy to initiate the process of bubble nucleation in a superheated fluid. These detectors offer complete gamma-ray insensitivity when used to detect neutrons. They also provide controllable neutron-energy thresholds and excellent position resolution. SDDs are extraordinarily simple and inexpensive. BCs offer the promise of very high efficiency ({approximately}75%). A notable drawback for both technologies is temperature sensitivity. As a result of this problem, the temperature must be controlled whenever high accuracy is required, or harsh environmental conditions are encountered. The primary findings of this work are listed and briefly summarized below: (1) SDDs are ready to function as electronics-free neutron detectors on demand for arms-control applications. The elimination of electronics at the weapon's location greatly eases the negotiability of radiation-detection technologies in general. (2) As a result of their high efficiency and sharp energy threshold, current BCs are almost ready for use in the development of a next-generation active assay system. Development of an instrument based on appropriately safe materials is warranted. (3) Both kinds of bubble detectors are ready for use whenever very high gamma-ray fields must be confronted. Spent fuel MPC and A is a good example where this need presents itself. (4) Both kinds of bubble detectors have the potential to function as low-cost replacements for conventional neutron detectors such as {sup 3}He tubes. For SDDs, this requires finding some way to get boron into the detector. For BCs, this requires finding operating conditions permitting a high duty cycle.

  2. Particle detection systems and methods

    DOE Patents [OSTI]

    Morris, Christopher L.; Makela, Mark F.

    2010-05-11T23:59:59.000Z

    Techniques, apparatus and systems for detecting particles such as muons and neutrons. In one implementation, a particle detection system employs a plurality of drift cells, which can be for example sealed gas-filled drift tubes, arranged on sides of a volume to be scanned to track incoming and outgoing charged particles, such as cosmic ray-produced muons. The drift cells can include a neutron sensitive medium to enable concurrent counting of neutrons. The system can selectively detect devices or materials, such as iron, lead, gold, uranium, plutonium, and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can concurrently detect any unshielded neutron sources occupying the volume from neutrons emitted therefrom. If necessary, the drift cells can be used to also detect gamma rays. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.

  3. active anti-islanding method: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a Mixed-Integer Nonlinear Program (MINLP). .... After eliminating pi and rearranging terms, ..... Algorithm 2 will still detect when the active set remains unchanged and enter...

  4. Detection of bacterial endospores by means of ultrafast coherent raman spectroscopy 

    E-Print Network [OSTI]

    Pestov, Dmitry Sergeyevich

    2008-10-10T23:59:59.000Z

    This work is devoted to formulation and development of a laser spectroscopic technique for rapid detection of biohazards, such as Bacillus anthracis spores. Coherent anti-Stokes Raman scattering (CARS) is used as an underlying process for active...

  5. Detection of bacterial endospores by means of ultrafast coherent raman spectroscopy

    E-Print Network [OSTI]

    Pestov, Dmitry Sergeyevich

    2008-10-10T23:59:59.000Z

    This work is devoted to formulation and development of a laser spectroscopic technique for rapid detection of biohazards, such as Bacillus anthracis spores. Coherent anti-Stokes Raman scattering (CARS) is used as an underlying process for active...

  6. Direct In Vivo Electrochemical Detection of Haemoglobin in Red Blood Cells

    E-Print Network [OSTI]

    Toh, Rou Jun

    The electrochemical behavior of iron ion in haemoglobin provides insight to the chemical activity in the red blood cell which is important in the field of hematology. Herein, the detection of haemoglobin in human red blood ...

  7. Bayesian Processing for the Detection of Radioactive Contraband from Uncertain Measurements

    SciTech Connect (OSTI)

    Candy, J V; Sale, K; Guidry, B; Breitfeller, E; Manatt, D; Chambers, D

    2007-06-26T23:59:59.000Z

    With the increase in terrorist activities throughout the world, the need to develop techniques capable of detecting radioactive contraband in a timely manner is a critical requirement. The development of Bayesian processors for the detection of contraband stems from the fact that the posterior distribution is clearly multimodal eliminating the usual Gaussian-based processors. The development of a sequential bootstrap processor for this problem is discussed and shown how it is capable of providing an enhanced signal for eventual detection.

  8. Efficient Failure Detection for Mobile Robots Using Mixed-Abstraction Particle Filters

    E-Print Network [OSTI]

    Stachniss, Cyrill

    Efficient Failure Detection for Mobile Robots Using Mixed-Abstraction Particle Filters Christian the problem of online failure detection and isolation for mobile robots. The goal is to enable a mobile robot failures of mobile robots. It uses a hierarchy of process models to actively validate the model assumptions

  9. Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels

    DOE Patents [OSTI]

    Mathies, Richard A. (Moraga, CA); Singhal, Pankaj (Berkeley, CA); Xie, Jin (Walnut Creek, CA); Glazer, Alexander N. (Orinda, CA)

    2002-01-01T23:59:59.000Z

    This invention relates to a microfabricated capillary electrophoresis chip for detecting multiple redox-active labels simultaneously using a matrix coding scheme and to a method of selectively labeling analytes for simultaneous electrochemical detection of multiple label-analyte conjugates after electrophoretic or chromatographic separation.

  10. QueueTrak: Automated Line Length Detection using a Wireless Sensor Network

    E-Print Network [OSTI]

    Whitehouse, Kamin

    , it uses a series of custom active infrared sensors to detect the length of a line in a store or restaurant the design, implementation, and evaluation of QueueTrak, a sensor network that measures the length of linesQueueTrak: Automated Line Length Detection using a Wireless Sensor Network Jared Alexander, Matthew

  11. Detection and treatment of chemical weapons and/or biological pathogens

    DOE Patents [OSTI]

    Mariella Jr., Raymond P.

    2004-09-07T23:59:59.000Z

    A system for detection and treatment of chemical weapons and/or biological pathogens uses a detector system, an electrostatic precipitator or scrubber, a circulation system, and a control. The precipitator or scrubber is activated in response to a signal from the detector upon the detection of chemical weapons and/or biological pathogens.

  12. active space implementationwith: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on the secondary, HST has a scattered light level that prevents it from detecting extra-solar planets. Our simulations show that by using an active mirror (400-1000 actuators) in...

  13. active optical sorting: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on the secondary, HST has a scattered light level that prevents it from detecting extra-solar planets. Our simulations show that by using an active mirror (400-1000 actuators) in...

  14. active space multiconfiguration: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on the secondary, HST has a scattered light level that prevents it from detecting extra-solar planets. Our simulations show that by using an active mirror (400-1000 actuators) in...

  15. alert telescope active: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on the secondary, HST has a scattered light level that prevents it from detecting extra-solar planets. Our simulations show that by using an active mirror (400-1000 actuators) in...

  16. activity disease duration: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    vaccination Read, Andrew 10 X-ray flares and the duration of engine activity in gamma-ray bursts Astrophysics (arXiv) Summary: The detection of bright X-ray flares superimposed...

  17. High resolution 3D insider detection and tracking.

    SciTech Connect (OSTI)

    Nelson, Cynthia Lee

    2003-09-01T23:59:59.000Z

    Vulnerability analysis studies show that one of the worst threats against a facility is that of an active insider during an emergency evacuation. When a criticality or other emergency alarm occurs, employees immediately proceed along evacuation routes to designated areas. Procedures are then implemented to account for all material, classified parts, etc. The 3-Dimensional Video Motion Detection (3DVMD) technology could be used to detect and track possible insider activities during alarm situations, as just described, as well as during normal operating conditions. The 3DVMD technology uses multiple cameras to create 3-dimensional detection volumes or zones. Movement throughout detection zones is tracked and high-level information, such as the number of people and their direction of motion, is extracted. In the described alarm scenario, deviances of evacuation procedures taken by an individual could be immediately detected and relayed to a central alarm station. The insider could be tracked and any protected items removed from the area could be flagged. The 3DVMD technology could also be used to monitor such items as machines that are used to build classified parts. During an alarm, detections could be made if items were removed from the machine. Overall, the use of 3DVMD technology during emergency evacuations would help to prevent the loss of classified items and would speed recovery from emergency situations. Further security could also be added by analyzing tracked behavior (motion) as it corresponds to predicted behavior, e.g., behavior corresponding with the execution of required procedures. This information would be valuable for detecting a possible insider not only during emergency situations, but also during times of normal operation.

  18. Trace Explosive Detection Using Nanosensors

    SciTech Connect (OSTI)

    Senesac, Larry R [ORNL; Thundat, Thomas George [ORNL

    2008-01-01T23:59:59.000Z

    Selective and sensitive detection of explosives is very important in countering terrorist threats. Detecting trace explosives has become a very complex and expensive endeavor because of a number of factors, such as the wide variety of materials that can be used as explosives, the lack of easily detectable signatures, the vast number of avenues by which these weapons can be deployed, and the lack of inexpensive sensors with high sensitivity and selectivity. High sensitivity and selectivity, combined with the ability to lower the deployment cost of sensors using mass production, is essential in winning the war on explosives-based terrorism. Nanosensors have the potential to satisfy all the requirements for an effective platform for the trace detection of explosives.

  19. Idaho National Laboratory Supervisory Control and Data Acquisition Intrusion Detection System (SCADA IDS)

    SciTech Connect (OSTI)

    Jared Verba; Michael Milvich

    2008-05-01T23:59:59.000Z

    Current Intrusion Detection System (IDS) technology is not suited to be widely deployed inside a Supervisory, Control and Data Acquisition (SCADA) environment. Anomaly- and signature-based IDS technologies have developed methods to cover information technology-based networks activity and protocols effectively. However, these IDS technologies do not include the fine protocol granularity required to ensure network security inside an environment with weak protocols lacking authentication and encryption. By implementing a more specific and more intelligent packet inspection mechanism, tailored traffic flow analysis, and unique packet tampering detection, IDS technology developed specifically for SCADA environments can be deployed with confidence in detecting malicious activity.

  20. Simultaneous Detection and Registration for Ileo-Cecal Valve Detection in 3D CT Colonography

    E-Print Network [OSTI]

    Barbu, Adrian

    Simultaneous Detection and Registration for Ileo-Cecal Valve Detection in 3D CT Colonography Le Lu1-Cecal Valve (ICV) detection in both clean and tagged 3D CT colonography scans. Our final ICV detection system

  1. Wise detections of known QSOs at redshifts greater than six

    SciTech Connect (OSTI)

    Blain, Andrew W. [Physics and Astronomy, University of Leicester, 1 University Road, Leicester LE1 7RH (United Kingdom); Assef, Roberto; Stern, Daniel; Tsai, Chao-Wei; Eisenhardt, Peter [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Bridge, Carrie [California Institute of Technology, 249-17, Pasadena, CA 91125 (United States); Benford, Dominic [Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Jarrett, Tom [Astronomy Department, University of Cape Town (South Africa); Cutri, Roc [Infrared Processing and Analysis Center, California Institute of Technology, MS100-22, Pasadena, CA 91125 (United States); Petty, Sara [Virginia Tech, Department of Physics MC 0435, 910 Drillfield Drive, Blacksburg, VA 24061 (United States); Wu, Jingwen; Wright, Edward L., E-mail: ab520@le.ac.uk [Division of Astronomy and Astrophysics, University of California, Los Angeles, Physics and Astronomy Building, 430 Portola Plaza, Los Angeles, CA 90095-1547 (United States)

    2013-12-01T23:59:59.000Z

    We present WISE All-Sky mid-infrared (IR) survey detections of 55% (17/31) of the known QSOs at z > 6 from a range of surveys: the SDSS, the CFHT-LS, FIRST, Spitzer, and UKIDSS. The WISE catalog thus provides a substantial increase in the quantity of IR data available for these sources: 17 are detected in the WISE W1 (3.4 ?m) band, 16 in W2 (4.6 ?m), 3 in W3 (12 ?m), and 0 in W4 (22 ?m). This is particularly important with Spitzer in its warm-mission phase and no faint follow-up capability at wavelengths longward of 5 ?m until the launch of James Webb Space Telescope (JWST). WISE thus provides a useful tool for understanding QSOs found in forthcoming large-area optical/IR sky surveys using PanSTARRS, SkyMapper, VISTA, DES, and LSST. The rest-UV properties of the WISE-detected and the WISE-non-detected samples differ: the detections have brighter i/z-band magnitudes and redder rest-UV colors. This suggests that a more aggressive hunt for very high redshift QSOs by combining WISE W1 and W2 data with red, observed optical colors could be effective at least for a subset of dusty candidate QSOs. Stacking the WISE images of the WISE-non-detected QSOs indicates that they are, on average, significantly fainter than the WISE-detected examples, and are thus not narrowly missing detection in the WISE catalog. The WISE catalog detection of three of our sample in the W3 band indicates that their mid-IR flux can be detected individually, although there is no stacked W3 detection of sources detected in W1 but not W3. Stacking analyses of WISE data for large active galactic nucleus samples will be a useful tool, and high-redshift QSOs of all types will be easy targets for JWST.

  2. Detecting fission from special nuclear material sources

    DOE Patents [OSTI]

    Rowland, Mark S. (Alamo, CA); Snyderman, Neal J. (Berkeley, CA)

    2012-06-05T23:59:59.000Z

    A neutron detector system for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly into information that a first responder can use to discriminate materials. The system comprises counting neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source. The system includes a graphing component that displays the plot of the neutron distribution from the unknown source over a Poisson distribution and a plot of neutrons due to background or environmental sources. The system further includes a known neutron source placed in proximity to the unknown source to actively interrogate the unknown source in order to accentuate differences in neutron emission from the unknown source from Poisson distributions and/or environmental sources.

  3. Review of Current Neutron Detection Systems for Emergency Response

    SciTech Connect (OSTI)

    Mukhopadhyay, S. [NSTec; Maurer, R. [NSTec; Guss, P. [NSTec; Kruschwitz, C. [NSTec

    2014-09-01T23:59:59.000Z

    Neutron detectors are used in a myriad of applications—from safeguarding special nuclear materials (SNM) to determining lattice spacing in soft materials. The transformational changes taking place in neutron detection and imaging techniques in the last few years are largely being driven by the global shortage of helium-3 (3He). This article reviews the status of neutron sensors used specifically for SNM detection in radiological emergency response. These neutron detectors must be highly efficient, be rugged, have fast electronics to measure neutron multiplicity, and be capable of measuring direction of the neutron sources and possibly image them with high spatial resolution. Neutron detection is an indirect physical process: neutrons react with nuclei in materials to initiate the release of one or more charged particles that produce electric signals that can be processed by the detection system. Therefore, neutron detection requires conversion materials as active elements of the detection system; these materials may include boron-10 (10B), lithium-6 (6Li), and gadollinium-157 (157Gd), to name a few, but the number of materials available for neutron detection is limited. However, in recent years, pulse-shape-discriminating plastic scintillators, scintillators made of helium-4 (4He) under high pressure, pillar and trench semiconductor diodes, and exotic semiconductor neutron detectors made from uranium oxide and other materials have widely expanded the parameter space in neutron detection methodology. In this article we will pay special attention to semiconductor-based neutron sensors. Modern micro-fabricated nanotubes covered inside with neutron converter materials and with very high aspect ratios for better charge transport will be discussed.

  4. Vapor generation methods for explosives detection research. ...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Vapor generation methods for explosives detection research. Vapor generation methods for explosives detection research. Abstract: The generation of calibrated vapor samples of...

  5. Detection of the internal corrosion in pipeline

    E-Print Network [OSTI]

    2006-10-17T23:59:59.000Z

    Detection of the internal corrosion in pipeline. Hyeonbae Kang. In this talk I will explain our new methods to detect internal corrosions in pipelines.

  6. Unexpected, Stable Form of Uranium Detected | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unexpected, Stable Form of Uranium Detected Unexpected, Stable Form of Uranium Detected Insights on underappreciated reaction could shed light on environmental cleanup options...

  7. Radio frequency detection assembly and method for detecting radio frequencies

    DOE Patents [OSTI]

    Cown, Steven H. (Rigby, ID); Derr, Kurt Warren (Idaho Falls, ID)

    2010-03-16T23:59:59.000Z

    A radio frequency detection assembly is described and which includes a radio frequency detector which detects a radio frequency emission produced by a radio frequency emitter from a given location which is remote relative to the radio frequency detector; a location assembly electrically coupled with the radio frequency detector and which is operable to estimate the location of the radio frequency emitter from the radio frequency emission which has been received; and a radio frequency transmitter electrically coupled with the radio frequency detector and the location assembly, and which transmits a radio frequency signal which reports the presence of the radio frequency emitter.

  8. Threshold Verification Technique for Network Intrusion Detection System

    E-Print Network [OSTI]

    Faizal, M A; Shahrin, S; Robiah, Y; Rahayu, S Siti; Nazrulazhar, B

    2009-01-01T23:59:59.000Z

    Internet has played a vital role in this modern world, the possibilities and opportunities offered are limitless. Despite all the hype, Internet services are liable to intrusion attack that could tamper the confidentiality and integrity of important information. An attack started with gathering the information of the attack target, this gathering of information activity can be done as either fast or slow attack. The defensive measure network administrator can take to overcome this liability is by introducing Intrusion Detection Systems (IDSs) in their network. IDS have the capabilities to analyze the network traffic and recognize incoming and on-going intrusion. Unfortunately the combination of both modules in real time network traffic slowed down the detection process. In real time network, early detection of fast attack can prevent any further attack and reduce the unauthorized access on the targeted machine. The suitable set of feature selection and the correct threshold value, add an extra advantage for I...

  9. Detecting Density Variations and Nanovoids

    SciTech Connect (OSTI)

    Miller, Michael K [ORNL; Longstreth-Spoor, L. [Washington University, St. Louis; Kelton, K. F. [Washington University, St. Louis

    2011-01-01T23:59:59.000Z

    A combination of simulated and experimental data has been used to investigate the size range of nanovoids that can be detected in atom probe tomography data. Simulated atom probe tomography data have revealed that nanovoids as small as 1 nm in diameter can be detected in atom probe tomography data with the use of iso-density surfaces. Iso-density surfaces may be used to quantify the size, morphology and number density of nanovoids and other variations in density in atom probe tomography data. Experimental data from an aluminum-yttrium-iron metallic glass ribbon have revealed the effectiveness of this approach. Combining iso-density surfaces with atom maps also permits the segregation of solute to the nanovoids to be investigated. Field ion microscopy and thin section atom maps have also been used to detect pores and larger voids.

  10. Discriminating ultrasonic proximity detection system

    DOE Patents [OSTI]

    Annala, Wayne C. (Durango, CO)

    1989-01-01T23:59:59.000Z

    This invention uses an ultrasonic transmitter and receiver and a microprocessor to detect the presence of an object. In the reset mode the invention uses a plurality of echoes from each ultrasonic burst to create a reference table of the echo-burst-signature of the empty monitored environment. The invention then processes the reference table so that it only uses the most reliable data. In the detection mode the invention compares the echo-burst-signature of the present environment with the reference table, detecting an object if there is a consistent difference between the echo-burst-signature of the empty monitored environment recorded in the reference table and the echo-burst-signature of the present environment.

  11. GMTI radar minimum detectable velocity.

    SciTech Connect (OSTI)

    Richards, John Alfred

    2011-04-01T23:59:59.000Z

    Minimum detectable velocity (MDV) is a fundamental consideration for the design, implementation, and exploitation of ground moving-target indication (GMTI) radar imaging modes. All single-phase-center air-to-ground radars are characterized by an MDV, or a minimum radial velocity below which motion of a discrete nonstationary target is indistinguishable from the relative motion between the platform and the ground. Targets with radial velocities less than MDV are typically overwhelmed by endoclutter ground returns, and are thus not generally detectable. Targets with radial velocities greater than MDV typically produce distinct returns falling outside of the endoclutter ground returns, and are thus generally discernible using straightforward detection algorithms. This document provides a straightforward derivation of MDV for an air-to-ground single-phase-center GMTI radar operating in an arbitrary geometry.

  12. Outlier Detection Rules for Fault Detection in Solar Photovoltaic Arrays

    E-Print Network [OSTI]

    Lehman, Brad

    , MPPT of the PV inverters, high fault impedance, or degradation of solar cells [1]. Without proper fault Abstract-- Solar photovoltaic (PV) arrays are unique power sources that may have uncleared fault current when utilizing conventional overcurrent protection devices. To monitor the PV operation and detect

  13. Ultrahigh Energy Cosmic Rays Detection

    E-Print Network [OSTI]

    Carla Aramo

    2005-09-06T23:59:59.000Z

    The paper describes methods used for the detection of cosmic rays with energies above 10^18 eV (UHECR, UltraHigh Energy Cosmic Rays). It had been anticipated there would be a cutoff in the energy spectrum of primary cosmic rays around 3 10^19 eV induced by their interaction with the 2.7 K primordial photons. This has become known as the GZK cutoff. However, several showers have been detected with estimated primary energy exceeding this limit.

  14. Project of the underwater system for chemical threat detection

    E-Print Network [OSTI]

    Silarski, M; Moskal, P; Smolis, M; Tadeja, S

    2015-01-01T23:59:59.000Z

    In this article we describe a novel method for the detection of explosives and other hazardous substances in the marine environment using neutron activation. Unlike the other considered methods based on this technique we propose to use guides forneutron and gamma quanta which speeds up and simplifies identification. Moreover, it may provide a determination of the density distribution of a dangerous substance. First preliminary results of Monte Carlo simulations dedicated for design of a device exploiting this method are also presented.

  15. Towards the detection of magnetohydrodynamics instabilities in a fusion reactor

    SciTech Connect (OSTI)

    Sozzi, Carlo, E-mail: sozzi@ifp.cnr.it; Alessi, E., E-mail: sozzi@ifp.cnr.it; Figini, L., E-mail: sozzi@ifp.cnr.it; Galperti, G., E-mail: sozzi@ifp.cnr.it; Lazzaro, E., E-mail: sozzi@ifp.cnr.it; Marchetto, C., E-mail: sozzi@ifp.cnr.it; Nowak, S. [Istituto di Fisica del Plasma, CNR, EURATOM-ENEA Association, Milano (Italy); Mosconi, M. [Dipartimento di Energia, Politecnico di Milano, Milano (Italy)

    2014-08-21T23:59:59.000Z

    Various active control strategies of the Neoclassical tearing modes are being studied in present tokamaks using established detection techniques which exploit the measurements of the fluctuations of the magnetic field and of the electron temperature. The extrapolation of such techniques to the fusion reactor scale is made problematic by the neutron fluence and by the physics conditions related to the high plasma temperature and density which degrade the spatial resolution of such measurements.

  16. Mechanical approach to the neutrons spectra collimation and detection

    SciTech Connect (OSTI)

    Sadeghi, H.; Roshan, M. V. [Energy Engineering and Physics Department, Amirkabir University of Technology, Tehran (Iran, Islamic Republic of)

    2014-11-15T23:59:59.000Z

    Neutrons spectra from most of known sources require being collimated for numerous applications; among them one is the Neutron Activation Analysis. High energy neutrons are collimated through a mechanical procedure as one of the most promising methods. The output energy of the neutron beam depends on the velocity of the rotating Polyethylene disks. The collimated neutrons are then measured by an innovative detection technique with high accuracy.

  17. Noise canceling in-situ detection

    DOE Patents [OSTI]

    Walsh, David O.

    2014-08-26T23:59:59.000Z

    Technologies applicable to noise canceling in-situ NMR detection and imaging are disclosed. An example noise canceling in-situ NMR detection apparatus may comprise one or more of a static magnetic field generator, an alternating magnetic field generator, an in-situ NMR detection device, an auxiliary noise detection device, and a computer.

  18. RESEARCH ARTICLE Open Access Rac3 induces a molecular pathway triggering

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines Caroline Gest1* , Ulrich Joimel1 cancer cell lines, MDA-MB-231 and MCF-7: both express Rac3, but MDA-MB-231 expresses more activated Rho secretion profiles were also analyzed. In the non-invasive MCF-7 line; Rac3 did not influence any

  19. Scalable Techniques for Anomaly Detection

    E-Print Network [OSTI]

    Yadav, Sandeep 1985-

    2012-08-20T23:59:59.000Z

    -level domains. We deploy this tool at the edge of a university campus network for evaluation. Secondly, we focus on domain-fluxing botnet detection by exploiting the high entropy inherent in the set of domains used for locating the Command and Control (C...

  20. Anomalous change detection in imagery

    DOE Patents [OSTI]

    Theiler, James P. (Los Alamos, NM); Perkins, Simon J. (Santa Fe, NM)

    2011-05-31T23:59:59.000Z

    A distribution-based anomaly detection platform is described that identifies a non-flat background that is specified in terms of the distribution of the data. A resampling approach is also disclosed employing scrambled resampling of the original data with one class specified by the data and the other by the explicit distribution, and solving using binary classification.

  1. Explosive detection research and development

    SciTech Connect (OSTI)

    Malotky, L.O.

    1988-01-01T23:59:59.000Z

    The detection of explosives carried by a passenger or included in checked baggage is a priority objective of the Federal Aviation Administration's (FAA) Security Research and Development Program. Significant accomplishments have been made in the detection of explosives in checked baggage. A technology, thermal neutron analysis, has been developed and tested extensively in airports with actual passenger baggage. The screening of people for explosives is also progressing with laboratory testing underway of an integrated passenger screening portal. The portal is designed to extract and detect not only the more volatile explosives but also the low-vapor-pressure military explosives. In addition to these two mature technologies, the FAA is also funding research in new technologies for bulk and vapor detection of explosives to identify and refine approaches which will be more efficient and effective. The ultimate objective is to field systems to protect the traveling public from terrorist-placed explosives without interrupting the free flow of people and materials we have grown to expect.

  2. Image Mining: Detecting Deforestation Patterns

    E-Print Network [OSTI]

    Camara, Gilberto

    54 Chapter IV Image Mining: Detecting Deforestation Patterns Through Satellites Marcelino Pereira to analyze satellite images and extract knowledge from this kind of data. The Amazonia deforestation problem of change on deforested areas of Amazonia. The purpose of the authors is to present relevant technologies

  3. Detection of explosives in soils

    DOE Patents [OSTI]

    Chambers, William B. (Edgewood, NM); Rodacy, Philip J. (Albuquerque, NM); Phelan, James M. (Bosque Farms, NM); Woodfin, Ronald L. (Sandia Park, NM)

    2002-01-01T23:59:59.000Z

    An apparatus and method for detecting explosive-indicating compounds in subsurface soil. The apparatus has a probe with an adsorbent material on some portion of its surface that can be placed into soil beneath the ground surface, where the adsorbent material can adsorb at least one explosive-indicating compound. The apparatus additional has the capability to desorb the explosive-indicating compound through heating or solvent extraction. A diagnostic instrument attached to the probe detects the desorbed explosive-indicating compound. In the method for detecting explosive-indicating compounds in soil, the sampling probe with an adsorbent material on at least some portion of a surface of the sampling probe is inserted into the soil to contact the adsorbent material with the soil. The explosive-indicating compounds are then desorbed and transferred as either a liquid or gas sample to a diagnostic tool for analysis. The resulting gas or liquid sample is analyzed using at least one diagnostic tool selected from the group consisting of an ion-mobility spectrometer, a gas chromatograph, a high performance liquid chromatograph, a capillary electrophoresis chromatograph, a mass spectrometer, a Fourier-transform infrared spectrometer and a Raman spectrometer to detect the presence of explosive-indicating compounds.

  4. Detect

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisitingContract Management FermiDavid Turner David3Depth ProfilefromRefinement

  5. detection

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA Approved:AdministrationAnalysisDarby Dietrich5 |0/%2A en6/%2A9/%2A en NNSA

  6. Secondary Energy Infobook Activities (19 Activities)'

    Broader source: Energy.gov (indexed) [DOE]

    Infobook Activities (19 Activities) Grades: 9-12 Topics: Energy Basics Owner: NEED This educational material is brought to you by the U.S. Department of Energy's Office of Energy...

  7. Activated Boron Nitride Derived from Activated Carbon

    E-Print Network [OSTI]

    Zettl, Alex

    combination of chemical, thermal, and electrical properties. The utility of activated carbon suggests is characterized by scanning electron microscopy, high-resolution transmission electron microscopy, electron energy loss spectroscopy, and surface area analysis. The activated BN microstructure is similar

  8. Method for detecting toxic gases

    DOE Patents [OSTI]

    Stetter, J.R.; Zaromb, S.; Findlay, M.W. Jr.

    1991-10-08T23:59:59.000Z

    A method is disclosed which is capable of detecting low concentrations of a pollutant or other component in air or other gas. This method utilizes a combination of a heating filament having a catalytic surface of a noble metal for exposure to the gas and producing a derivative chemical product from the component. An electrochemical sensor responds to the derivative chemical product for providing a signal indicative of the product. At concentrations in the order of about 1-100 ppm of tetrachloroethylene, neither the heating filament nor the electrochemical sensor is individually capable of sensing the pollutant. In the combination, the heating filament converts the benzyl chloride to one or more derivative chemical products which may be detected by the electrochemical sensor. 6 figures.

  9. Detection of a concealed object

    DOE Patents [OSTI]

    Keller, Paul E [Richland, WA; Hall, Thomas E [Kennewick, WA; McMakin, Douglas L [Richland, WA

    2010-11-16T23:59:59.000Z

    Disclosed are systems, methods, devices, and apparatus to determine if a clothed individual is carrying a suspicious, concealed object. This determination includes establishing data corresponding to an image of the individual through interrogation with electromagnetic radiation in the 200 MHz to 1 THz range. In one form, image data corresponding to intensity of reflected radiation and differential depth of the reflecting surface is received and processed to detect the suspicious, concealed object.

  10. Detection of a concealed object

    DOE Patents [OSTI]

    Keller, Paul E. (Richland, WA); Hall, Thomas E. (Kennewick, WA); McMakin, Douglas L. (Richland, WA)

    2008-04-29T23:59:59.000Z

    Disclosed are systems, methods, devices, and apparatus to determine if a clothed individual is carrying a suspicious, concealed object. This determination includes establishing data corresponding to an image of the individual through interrogation with electromagnetic radiation in the 200 MHz to 1 THz range. In one form, image data corresponding to intensity of reflected radiation and differential depth of the reflecting surface is received and processed to detect the suspicious, concealed object.

  11. Multiplex detection of agricultural pathogens

    DOE Patents [OSTI]

    Siezak, Thomas R.; Gardner, Shea; Torres, Clinton; Vitalis, Elizabeth; Lenhoff, Raymond J.

    2013-01-15T23:59:59.000Z

    Described are kits and methods useful for detection of agricultural pathogens in a sample. Genomic sequence information from agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay and/or an array assay to successfully identify the presence or absence of pathogens in a sample.

  12. Detection of malicious computer executables

    DOE Patents [OSTI]

    Cai, Dongming M. (Los Alamos, NM); Gokhale, Maya (Los Alamos, NM)

    2009-04-14T23:59:59.000Z

    A method of detecting malicious binary executable files is accomplished by inputting a binary executable file; converting the binary executable file to byte hexadecimal text strings; calculating the frequency of each byte pattern in the byte hexadecimal text strings; selecting characteristic byte pattern frequencies as discriminating features; classifying the discriminating features as malicious or benign; labeling the binary executable file as malicious or benign; and outputting the labeled malicious or benign binary executable file.

  13. Multiplex detection of agricultural pathogens

    DOE Patents [OSTI]

    McBride, Mary Teresa (Brentwood, CA); Slezak, Thomas Richard (Livermore, CA); Messenger, Sharon Lee (Kensington, CA)

    2010-09-14T23:59:59.000Z

    Described are kits and methods useful for detection of seven agricultural pathogens (BPSV; BHV; BVD; FMDV; BTV; SVD; and VESV) in a sample. Genomic sequence information from 7 agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

  14. Activity Based Costing

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-03-28T23:59:59.000Z

    Activity Based Costing (ABC) is method for developing cost estimates in which the project is subdivided into discrete, quantifiable activities or a work unit. This chapter outlines the Activity Based Costing method and discusses applicable uses of ABC.

  15. Semi autonomous mine detection system

    SciTech Connect (OSTI)

    Douglas Few; Roelof Versteeg; Herman Herman

    2010-04-01T23:59:59.000Z

    CMMAD is a risk reduction effort for the AMDS program. As part of CMMAD, multiple instances of semi autonomous robotic mine detection systems were created. Each instance consists of a robotic vehicle equipped with sensors required for navigation and marking, a countermine sensors and a number of integrated software packages which provide for real time processing of the countermine sensor data as well as integrated control of the robotic vehicle, the sensor actuator and the sensor. These systems were used to investigate critical interest functions (CIF) related to countermine robotic systems. To address the autonomy CIF, the INL developed RIK was extended to allow for interaction with a mine sensor processing code (MSPC). In limited field testing this system performed well in detecting, marking and avoiding both AT and AP mines. Based on the results of the CMMAD investigation we conclude that autonomous robotic mine detection is feasible. In addition, CMMAD contributed critical technical advances with regard to sensing, data processing and sensor manipulation, which will advance the performance of future fieldable systems. As a result, no substantial technical barriers exist which preclude – from an autonomous robotic perspective – the rapid development and deployment of fieldable systems.

  16. Compensated intruder-detection systems

    DOE Patents [OSTI]

    McNeilly, David R. (Maryville, TN); Miller, William R. (Andersonville, TN)

    1984-01-01T23:59:59.000Z

    Intruder-detection systems in which intruder-induced signals are transmitted through a medium also receive spurious signals induced by changes in a climatic condition affecting the medium. To combat this, signals received from the detection medium are converted to a first signal. The system also provides a reference signal proportional to climate-induced changes in the medium. The first signal and the reference signal are combined for generating therefrom an output signal which is insensitive to the climatic changes in the medium. An alarm is energized if the output signal exceeds a preselected value. In one embodiment, an acoustic cable is coupled to a fence to generate a first electrical signal proportional to movements thereof. False alarms resulting from wind-induced movements of the fence (detection medium) are eliminated by providing an anemometer-driven voltage generator to provide a reference voltage proportional to the velocity of wind incident on the fence. An analog divider receives the first electrical signal and the reference signal as its numerator and denominator inputs, respectively, and generates therefrom an output signal which is insensitive to the wind-induced movements in the fence.

  17. Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches

    DOE Patents [OSTI]

    McCutchen-Maloney, Sandra L. (Pleasanton, CA)

    2002-01-01T23:59:59.000Z

    Chimeric proteins having both DNA mutation binding activity and nuclease activity are synthesized by recombinant technology. The proteins are of the general formula A-L-B and B-L-A where A is a peptide having DNA mutation binding activity, L is a linker and B is a peptide having nuclease activity. The chimeric proteins are useful for detection and identification of DNA sequence variations including DNA mutations (including DNA damage and mismatches) by binding to the DNA mutation and cutting the DNA once the DNA mutation is detected.

  18. Method and apparatus for enhanced detection of toxic agents

    DOE Patents [OSTI]

    Greenbaum, Elias; Rodriguez, Jr., Miguel; Wu, Jie Jayne; Qi, Hairong

    2013-10-01T23:59:59.000Z

    A biosensor based detection of toxins includes enhancing a fluorescence signal by concentrating a plurality of photosynthetic organisms in a fluid into a concentrated region using biased AC electro-osmosis. A measured photosynthetic activity of the photosynthetic organisms is obtained in the concentrated region, where chemical, biological or radiological agents reduce a nominal photosynthetic activity of the photosynthetic organisms. A presence of the chemical, biological and/or radiological agents or precursors thereof, is determined in the fluid based on the measured photosynthetic activity of the concentrated plurality of photosynthetic organisms. A lab-on-a-chip system is used for the concentrating step. The presence of agents is determined from feature vectors, obtained from processing a time dependent signal using amplitude statistics and/or time-frequency analysis, relative to a control signal. A linear discriminant method including support vector machine classification (SVM) is used to identify the agents.

  19. Detection of energetic particles and gamma rays General radiation detection concepts

    E-Print Network [OSTI]

    Peletier, Reynier

    Detection of energetic particles and gamma rays General radiation detection concepts Peter · heavy charged particles · electrons ­ neutral particles · neutrons · neutrinos · General radiation detection concepts ­ pulse mode operation ­ energy spectrum ­ detector efficiency ­ timing · Radiation

  20. Active stewardship: sustainable future

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Active stewardship: sustainable future Active stewardship: sustainable future Energy sustainability is a daunting task: How do we develop top-notch innovations with some of the...

  1. Arterial Traffic Activity Estimation

    E-Print Network [OSTI]

    Yang, Qichi

    2013-01-01T23:59:59.000Z

    grid map.. detection approaches, grid map-based approaches are alsoIn 3.3.3, we introduce a grid map approach for object height

  2. Modeling Prostate Cancer Detection Probability, with Applications

    E-Print Network [OSTI]

    Serfling, Robert

    investigating causes and treatments. Robert Serfling Modeling Prostate Cancer Detection Probability cancer present as well as tumor nodule sizes, to judge clinical significance before treatment selectionModeling Prostate Cancer Detection Probability, with Applications Robert Serfling1 University

  3. Novel absorption detection techniques for capillary electrophoresis

    SciTech Connect (OSTI)

    Xue, Y.

    1994-07-27T23:59:59.000Z

    Capillary electrophoresis (CE) has emerged as one of the most versatile separation methods. However, efficient separation is not sufficient unless coupled to adequate detection. The narrow inner diameter (I.D.) of the capillary column raises a big challenge to detection methods. For UV-vis absorption detection, the concentration sensitivity is only at the {mu}M level. Most commercial CE instruments are equipped with incoherent UV-vis lamps. Low-brightness, instability and inefficient coupling of the light source with the capillary limit the further improvement of UV-vis absorption detection in CE. The goals of this research have been to show the utility of laser-based absorption detection. The approaches involve: on-column double-beam laser absorption detection and its application to the detection of small ions and proteins, and absorption detection with the bubble-shaped flow cell.

  4. Suspended microchannel resonators for biomolecular detection

    E-Print Network [OSTI]

    Burg, Thomas P. (Thomas Peter)

    2005-01-01T23:59:59.000Z

    Microfabricated transducers enable the label-free detection of biological molecules in nanoliter sized samples. Integrating microfluidic detection and sample-preparation can greatly leverage experimental efforts in systems ...

  5. A New Methodology for Early Anomaly Detection of BWR Instabilities

    SciTech Connect (OSTI)

    Ivanov, K. N.

    2005-11-27T23:59:59.000Z

    The objective of the performed research is to develop an early anomaly detection methodology so as to enhance safety, availability, and operational flexibility of Boiling Water Reactor (BWR) nuclear power plants. The technical approach relies on suppression of potential power oscillations in BWRs by detecting small anomalies at an early stage and taking appropriate prognostic actions based on an anticipated operation schedule. The research utilizes a model of coupled (two-phase) thermal-hydraulic and neutron flux dynamics, which is used as a generator of time series data for anomaly detection at an early stage. The model captures critical nonlinear features of coupled thermal-hydraulic and nuclear reactor dynamics and (slow time-scale) evolution of the anomalies as non-stationary parameters. The time series data derived from this nonlinear non-stationary model serves as the source of information for generating the symbolic dynamics for characterization of model parameter changes that quantitatively represent small anomalies. The major focus of the presented research activity was on developing and qualifying algorithms of pattern recognition for power instability based on anomaly detection from time series data, which later can be used to formulate real-time decision and control algorithms for suppression of power oscillations for a variety of anticipated operating conditions. The research being performed in the framework of this project is essential to make significant improvement in the capability of thermal instability analyses for enhancing safety, availability, and operational flexibility of currently operating and next generation BWRs.

  6. Incipient Crack Detection in Composite Wind Turbine Blades

    SciTech Connect (OSTI)

    Taylor, Stuart G. [Los Alamos National Laboratory; Choi, Mijin [Chonbuk National University, Korea; Jeong, Hyomi [Chonbuk National University, Korea; Jang, Jae Kyeong [Chonbuk National University, Korea; Park, Gyuhae [Chonnam National University, Korea; Farinholt, Kevin [Commonwealth Center for Advanced Manufacturing, VA; Farrar, Charles R. [Los Alamos National Laboratory; Ammerman, Curtt N. [Los Alamos National Laboratory; Todd, Michael D. [Los Alamos National Laboratory; Lee, Jung-Ryul [Chonbuk National University, Korea

    2012-08-28T23:59:59.000Z

    This paper presents some analysis results for incipient crack detection in a 9-meter CX-100 wind turbine blade that underwent fatigue loading to failure. The blade was manufactured to standard specifications, and it underwent harmonic excitation at its first resonance using a hydraulically-actuated excitation system until reaching catastrophic failure. This work investigates the ability of an ultrasonic guided wave approach to detect incipient damage prior to the surfacing of a visible, catastrophic crack. The blade was instrumented with piezoelectric transducers, which were used in an active, pitchcatch mode with guided waves over a range of excitation frequencies. The performance results in detecting incipient crack formation in the fiberglass skin of the blade is assessed over the range of frequencies in order to determine the point at which the incipient crack became detectable. Higher excitation frequencies provide consistent results for paths along the rotor blade's carbon fiber spar cap, but performance falls off with increasing excitation frequencies for paths off of the spar cap. Lower excitation frequencies provide more consistent performance across all sensor paths.

  7. Radiation Detection Computational Benchmark Scenarios

    SciTech Connect (OSTI)

    Shaver, Mark W.; Casella, Andrew M.; Wittman, Richard S.; McDonald, Ben S.

    2013-09-24T23:59:59.000Z

    Modeling forms an important component of radiation detection development, allowing for testing of new detector designs, evaluation of existing equipment against a wide variety of potential threat sources, and assessing operation performance of radiation detection systems. This can, however, result in large and complex scenarios which are time consuming to model. A variety of approaches to radiation transport modeling exist with complementary strengths and weaknesses for different problems. This variety of approaches, and the development of promising new tools (such as ORNL’s ADVANTG) which combine benefits of multiple approaches, illustrates the need for a means of evaluating or comparing different techniques for radiation detection problems. This report presents a set of 9 benchmark problems for comparing different types of radiation transport calculations, identifying appropriate tools for classes of problems, and testing and guiding the development of new methods. The benchmarks were drawn primarily from existing or previous calculations with a preference for scenarios which include experimental data, or otherwise have results with a high level of confidence, are non-sensitive, and represent problem sets of interest to NA-22. From a technical perspective, the benchmarks were chosen to span a range of difficulty and to include gamma transport, neutron transport, or both and represent different important physical processes and a range of sensitivity to angular or energy fidelity. Following benchmark identification, existing information about geometry, measurements, and previous calculations were assembled. Monte Carlo results (MCNP decks) were reviewed or created and re-run in order to attain accurate computational times and to verify agreement with experimental data, when present. Benchmark information was then conveyed to ORNL in order to guide testing and development of hybrid calculations. The results of those ADVANTG calculations were then sent to PNNL for compilation. This is a report describing the details of the selected Benchmarks and results from various transport codes.

  8. Alternative Neutron Detection Testing Summary

    SciTech Connect (OSTI)

    Kouzes, Richard T.; Ely, James H.; Erikson, Luke E.; Kernan, Warnick J.; Lintereur, Azaree T.; Siciliano, Edward R.; Stromswold, David C.; Woodring, Mitchell L.

    2010-04-08T23:59:59.000Z

    Radiation portal monitors used for interdiction of illicit materials at borders include highly sensitive neutron detection systems. The main reason for having neutron detection capability is to detect fission neutrons from plutonium. Most currently deployed radiation portal monitors (RPMs) use neutron detectors based upon 3He-filled gas proportional counters, which are the most common large area neutron detector. This type of neutron detector is used in the TSA and other RPMs installed in international locations and in the Ludlum and Science Applications International Corporation RPMs deployed primarily for domestic applications. There is a declining supply of 3He in the world and, thus, methods to reduce the use of this gas in RPMs with minimal changes to the current system designs and sensitivity to cargo-borne neutrons are being investigated. Four technologies have been identified as being currently commercially available, potential alternative neutron detectors to replace the use of 3He in RPMs. These technologies are: 1) Boron trifluoride-filled proportional counters, 2) Boron-lined proportional counters, 3) Lithium-loaded glass fibers, and 4) Coated wavelength-shifting plastic fibers. Reported here is a summary of the testing carried out at Pacific Northwest National Laboratory on these technologies to date, as well as measurements on 3He tubes at various pressures. Details on these measurements are available in the referenced reports. Sponsors of these tests include the Department of Energy (DOE), Department of Homeland Security (DHS), and the Department of Defense (DoD), as well as internal Pacific Northwest National Laboratory funds.

  9. Feature detection for spatial templates

    SciTech Connect (OSTI)

    Robinson, K.

    1996-02-01T23:59:59.000Z

    The Color Medical Image System (CMIS), a program that uses segmented mapping techniques to obtain high resolution digital images, is currently trying to develop techniques to transfer microscopic glass slides to electronic image libraries. One technique that has been attempted is to use correlation techniques to scan the image. However, when segments of high magnification are used, it is difficult and time consuming to perform correlation techniques. This project investigates feature detection in microscopic images. Various techniques are implemented to detect the section of the image containing the most feature information, thereby making the correlation process more efficient. Three tests are implemented that eliminate the background in the image and calculate the mean (1st order technique), variance (2nd order technique), and ratio test (1st order technique) of the remaining pixel values. Background elimination involves deleting all pixel values above a certain experimental value from any calculations made. The source code for each of the three tests was implemented and tested on a number of images using the green color band. Each program outputs the box containing the most features and writes that section to a file to be displayed to the screen. A visual rank was also recorded so as to compare it the output of the tests. Each of the three tests proved to be successful. After comparing the visual rank to the output of the tests, it was determined that both first and second order techniques are effective in detecting features in microscopic images. Although all of the purposes and goals were met, this investigation should be expanded to include texturized images and the use of all three color bands.

  10. Digital Watermark Detection in Visual Multimedia Content

    E-Print Network [OSTI]

    Uhl, Andreas

    Digital Watermark Detection in Visual Multimedia Content Peter Meerwald Cumulative thesis (online or video. Watermark detection is an integral component of a watermarking system. This cumulative thesis. The computational effort for blind, spread-spectrum watermark detection is analyzed in- cluding the determination

  11. Fast Bayesian People Detection Gwenn Englebienne a

    E-Print Network [OSTI]

    Englebienne, Gwenn

    linearly on the number of people in the scene. When many people are present in the frame, detecting allFast Bayesian People Detection Gwenn Englebienne a Ben J.A. Kr¨ose a a Universiteit van Amsterdam for tracking people with fixed cameras, which automatically detects the number of people in a frame, is robust

  12. A PRIMER OF SIGNAL DETECTION THEORY

    E-Print Network [OSTI]

    Born, Richard

    A PRIMER OF SIGNAL DETECTION THEORY D. McNicol Lecturer in Applied Psychology, University of New in which the effects of signal detection theory have not been felt. The authoritative work on the subject, Green's & Swets' Signal Detection Theory and Psycho- physics (New York: Wiley) appearedjn 1966

  13. Multiplex detection of respiratory pathogens

    DOE Patents [OSTI]

    McBride, Mary (Brentwood, CA); Slezak, Thomas (Livermore, CA); Birch, James M. (Albany, CA)

    2012-07-31T23:59:59.000Z

    Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

  14. Pulsed helium ionization detection system

    DOE Patents [OSTI]

    Ramsey, R.S.; Todd, R.A.

    1985-04-09T23:59:59.000Z

    A helium ionization detection system is provided which produces stable operation of a conventional helium ionization detector while providing improved sensitivity and linearity. Stability is improved by applying pulsed dc supply voltage across the ionization detector, thereby modifying the sampling of the detectors output current. A unique pulse generator is used to supply pulsed dc to the detector which has variable width and interval adjust features that allows up to 500 V to be applied in pulse widths ranging from about 150 nsec to about dc conditions.

  15. Pulsed helium ionization detection system

    DOE Patents [OSTI]

    Ramsey, Roswitha S. (Knoxville, TN); Todd, Richard A. (Knoxville, TN)

    1987-01-01T23:59:59.000Z

    A helium ionization detection system is provided which produces stable operation of a conventional helium ionization detector while providing improved sensitivity and linearity. Stability is improved by applying pulsed dc supply voltage across the ionization detector, thereby modifying the sampling of the detectors output current. A unique pulse generator is used to supply pulsed dc to the detector which has variable width and interval adjust features that allows up to 500 V to be applied in pulse widths ranging from about 150 nsec to about dc conditions.

  16. Producing and Detecting Correlated atoms

    E-Print Network [OSTI]

    Christoph I. Westbrook; Martijn Schellekens; Aurélien Perrin; Valentina Krachmalnicoff; Jose Carlos Viana Gomes; Jean-Baptiste Trebbia; Jérôme Estčve; Hong Chang; Isabelle Bouchoule; Denis Boiron; Alain Aspect; Tom Jeltes; John McNamara; Wim Hogervorst; Wim Vassen

    2006-09-04T23:59:59.000Z

    We discuss experiments to produce and detect atom correlations in a degenerate or nearly degenerate gas of neutral atoms. First we treat the atomic analog of the celebrated Hanbury Brown Twiss experiment, in which atom correlations result simply from interference effects without any atom interactions.We have performed this experiment for both bosons and fermions. Next we show how atom interactions produce correlated atoms using the atomic analog of spontaneous four-wavemixing. Finally, we briefly mention experiments on a one dimensional gas on an atom chip in which correlation effects due to both interference and interactions have been observed.

  17. The Autonomous Pathogen Detection System

    SciTech Connect (OSTI)

    Dzenitis, J M; Makarewicz, A J

    2009-01-13T23:59:59.000Z

    We developed, tested, and now operate a civilian biological defense capability that continuously monitors the air for biological threat agents. The Autonomous Pathogen Detection System (APDS) collects, prepares, reads, analyzes, and reports results of multiplexed immunoassays and multiplexed PCR assays using Luminex{copyright} xMAP technology and flow cytometer. The mission we conduct is particularly demanding: continuous monitoring, multiple threat agents, high sensitivity, challenging environments, and ultimately extremely low false positive rates. Here, we introduce the mission requirements and metrics, show the system engineering and analysis framework, and describe the progress to date including early development and current status.

  18. Storm detection by electronic means

    E-Print Network [OSTI]

    Wooten, Allen Dewey

    1949-01-01T23:59:59.000Z

    equivalent circuit (figure 5), 14 ~744 r 50, 000 + r r = 7uu ouu ? 17u irrr 4. 1 Thus, the applied sigr 1 eg is not 245 volts, but 14 volts. This signal voltage is sufficient to cause Eb to drop froia 390 volts to 290 volts. I'Loni. , lly, C402 (Figure 3... and Mechanical College of Texas in partial fulfillment of the requirements for the deEree of MASTER OF SCIENCE IN ELECTRICAL ENGINEERING 1949 CONTENTS Introduction Theoretic. . l Consideration oi' Radar Storm Detection II. Extending =ffective R~ge of Radar...

  19. Detecting bioterrorism: Is chemistry enough?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisitingContract Management FermiDavid Turner David3DepthDetecting bioterrorism: Is

  20. Simulation and modeling for the stand-off radiation detection system (SORDS) using GEANT4

    SciTech Connect (OSTI)

    Hoover, Andrew S [Los Alamos National Laboratory; Wallace, Mark [Los Alamos National Laboratory; Galassi, Mark [Los Alamos National Laboratory; Mocko, Michal [Los Alamos National Laboratory; Palmer, David [Los Alamos National Laboratory; Schultz, Larry [Los Alamos National Laboratory; Tornga, Shawn [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    A Stand-Off Radiation Detection System (SORDS) is being developed through a joint effort by Raytheon, Los Alamos National Laboratory, Bubble Technology Industries, Radiation Monitoring Devices, and the Massachusetts Institute of Technology, for the Domestic Nuclear Detection Office (DNDO). The system is a mobile truck-based platform performing detection, imaging, and spectroscopic identification of gamma-ray sources. A Tri-Modal Imaging (TMI) approach combines active-mask coded aperture imaging, Compton imaging, and shadow imaging techniques. Monte Carlo simulation and modeling using the GEANT4 toolkit was used to generate realistic data for the development of imaging algorithms and associated software code.

  1. A Robust Aggregation Method for Quasi-blind Robots in an Active Environment

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    A Robust Aggregation Method for Quasi-blind Robots in an Active Environment Nazim Fat is through an active environment (stigmergy) and the only information they can receive is the local detection of the waves produced by other robots. The active environment obeys a cellular automaton rule and is simulated

  2. Anti-inflammatory and anti-oxidant activities of olmesartan medoxomil ameliorate experimental colitis in rats

    SciTech Connect (OSTI)

    Nagib, Marwa M. [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Misr International University, Cairo (Egypt); Tadros, Mariane G., E-mail: mirogeogo@yahoo.com [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt); ELSayed, Moushira I. [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Misr International University, Cairo (Egypt); Khalifa, Amani E. [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt)

    2013-08-15T23:59:59.000Z

    Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) driven through altered immune responses with production of proinflammatory cytokines. Many therapies are used, but side effects and loss of response limit long-term effectiveness. New therapeutic strategies are thus needed for patients who don't respond to current treatments. Recently, there is suggested involvement of the proinflammatory hormone angiotensin II in inflammatory bowel disease. The aim of this study was to investigate the possible role of olmesartan medoxomil (OLM-M), an angiotensin II receptor blocker in ameliorating ulcerative colitis. Colitis was induced in male Wistar rats by administration of 5% dextran sodium sulphate (DSS) in drinking water for 5 days. OLM-M (1, 3 and 10 mg/kg) was administered orally during 21 days prior to the induction of colitis, and for 5 days after. Sulfasalazine (500 mg/kg) was used as reference drug. All animals were tested for changes in colon length, disease activity index (DAI) and microscopic damage. Colon tissue concentration/activity of tumor necrosis alpha (TNF-?), myeloperoxidase (MPO), prostaglandin E2 (PGE2), reduced glutathione (GSH) and malondialdehyde (MDA) were assessed. Results showed that the OLM-M dose-dependently ameliorated the colonic histopathological and biochemical injuries, an effect that is comparable or even better than that of the standard sulfasalazine. These results suggest that olmesartan medoxomil may be effective in the treatment of UC through its anti-inflammatory and antioxidant effects. - Highlights: • Olmesartan medoximil reduced dextran sodium sulphate- induced colitis. • Mechanism involved anti-inflammatory and antioxidant effects dose- dependently. • It suppressed malondialdehyde and restored reduced glutathione levels. • It reduced inflammatory markers levels and histological changes.

  3. Early Lung Cancer Detection Program

    Broader source: Energy.gov [DOE]

    Since 2000, DOE has made screening for occupational lung cancer with low-dose helical computed tomography (CT) scans available to workers at high risk for lung cancer. Because former workers undertook essential activities to fulfill the Department's mission, many of them were at risk for lung cancer.

  4. Embedded Sensor System for Early Pathology Detection in Building Construction

    E-Print Network [OSTI]

    Torres, Santiago J Barro

    2009-01-01T23:59:59.000Z

    Structure pathology detection is an important security task in building construction, which is performed by an operator by looking manually for damages on the materials. This activity could be dangerous if the structure is hidden or difficult to reach. On the other hand, embedded devices and wireless sensor networks (WSN) are becoming popular and cheap, enabling the design of an alternative pathology detection system to monitor structures based on these technologies. This article introduces a ZigBee WSN system, intending to be autonomous, easy to use and with low power consumption. Its functional parts are fully discussed with diagrams, as well as the protocol used to collect samples from sensor nodes. Finally, several tests focused on range and power consumption of our prototype are shown, analysing whether the results obtained were as expected or not.

  5. Neutron Detection via Bubble Chambers

    SciTech Connect (OSTI)

    Jordan, David V.; Ely, James H.; Peurrung, Anthony J.; Bond, Leonard J.; Collar, J. I.; Flake, Matthew; Knopf, Michael A.; Pitts, W. K.; Shaver, Mark W.; Sonnenschein, Andrew; Smart, John E.; Todd, Lindsay C.

    2005-10-06T23:59:59.000Z

    The results of a Pacific Northwest National Laboratory (PNNL) exploratory research project investigating the feasibility of fast neutron detection using a suitably prepared and operated, pressure-cycled bubble chamber are described. The research was conducted along two parallel paths. Experiments with a slow pressure-release Halon chamber at the Enrico Fermi Institute at the University of Chicago showed clear bubble nucleation sensitivity to an AmBe neutron source and insensitivity to the 662 keV gammas from a 137Cs source. Bubble formation was documented via high-speed (1000 frames/sec) photography, and the acoustic signature of bubble formation was detected using a piezo-electric transducer element mounted on the base of the chamber. The chamber’s neutron sensitivity as a function of working fluid temperature was mapped out. The second research path consisted of the design, fabrication, and testing of a fast pressure-release Freon-134a chamber at PNNL. The project concluded with successful demonstrations of the PNNL chamber’s AmBe neutron source sensitivity and 137Cs gamma insensitivity. The source response tests of the PNNL chamber were documented with high-speed photography.

  6. Spectral analysis method for detecting an element

    DOE Patents [OSTI]

    Blackwood, Larry G [Idaho Falls, ID; Edwards, Andrew J [Idaho Falls, ID; Jewell, James K [Idaho Falls, ID; Reber, Edward L [Idaho Falls, ID; Seabury, Edward H [Idaho Falls, ID

    2008-02-12T23:59:59.000Z

    A method for detecting an element is described and which includes the steps of providing a gamma-ray spectrum which has a region of interest which corresponds with a small amount of an element to be detected; providing nonparametric assumptions about a shape of the gamma-ray spectrum in the region of interest, and which would indicate the presence of the element to be detected; and applying a statistical test to the shape of the gamma-ray spectrum based upon the nonparametric assumptions to detect the small amount of the element to be detected.

  7. Boron-10 ABUNCL Active Testing

    SciTech Connect (OSTI)

    Kouzes, Richard T.; Ely, James H.; Lintereur, Azaree T.; Siciliano, Edward R.

    2013-07-09T23:59:59.000Z

    The Department of Energy Office of Nuclear Safeguards and Security (NA-241) is supporting the project Coincidence Counting With Boron-Based Alternative Neutron Detection Technology at Pacific Northwest National Laboratory (PNNL) for the development of a 3He proportional counter alternative neutron coincidence counter. The goal of this project is to design, build and demonstrate a system based upon 10B-lined proportional tubes in a configuration typical for 3He-based coincidence counter applications. This report provides results from testing of the active mode of the General Electric Reuter-Stokes Alternative Boron-Based Uranium Neutron Coincidence Collar (ABUNCL) at Los Alamos National Laboratory using sources and fuel pins.

  8. NeuDetect: A Neural Network Data Mining Wireless Network Intrusion Detection System

    E-Print Network [OSTI]

    Ezeife, Christie

    NeuDetect: A Neural Network Data Mining Wireless Network Intrusion Detection System C.I. Ezeife wireless intrusion detection systems, this paper presents a method of applying artificial neural networks mining clas- sification technique to wireless network intrusion detection system. The proposed system

  9. Buried object detection in GPR images

    DOE Patents [OSTI]

    Paglieroni, David W; Chambers, David H; Bond, Steven W; Beer, W. Reginald

    2014-04-29T23:59:59.000Z

    A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

  10. Cellular telephone-based radiation detection instrument

    DOE Patents [OSTI]

    Craig, William W. (Pittsburg, CA); Labov, Simon E. (Berkeley, CA)

    2011-06-14T23:59:59.000Z

    A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

  11. Radiation Detection Materials and Systems | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Detection Materials and Systems SHARE Radiation Detection Materials and Systems ORNL's Nuclear Material Detection and Characterization programs are at the forefront of...

  12. Excitation optimization for damage detection

    SciTech Connect (OSTI)

    Bement, Matthew T [Los Alamos National Laboratory; Bewley, Thomas R [UCSD

    2009-01-01T23:59:59.000Z

    A technique is developed to answer the important question: 'Given limited system response measurements and ever-present physical limits on the level of excitation, what excitation should be provided to a system to make damage most detectable?' Specifically, a method is presented for optimizing excitations that maximize the sensitivity of output measurements to perturbations in damage-related parameters estimated with an extended Kalman filter. This optimization is carried out in a computationally efficient manner using adjoint-based optimization and causes the innovations term in the extended Kalman filter to be larger in the presence of estimation errors, which leads to a better estimate of the damage-related parameters in question. The technique is demonstrated numerically on a nonlinear 2 DOF system, where a significant improvement in the damage-related parameter estimation is observed.

  13. Explosives detection system and method

    DOE Patents [OSTI]

    Reber, Edward L. (Idaho Falls, ID); Jewell, James K. (Idaho Falls, ID); Rohde, Kenneth W. (Idaho Falls, ID); Seabury, Edward H. (Idaho Falls, ID); Blackwood, Larry G. (Idaho Falls, ID); Edwards, Andrew J. (Idaho Falls, ID); Derr, Kurt W. (Idaho Falls, ID)

    2007-12-11T23:59:59.000Z

    A method of detecting explosives in a vehicle includes providing a first rack on one side of the vehicle, the rack including a neutron generator and a plurality of gamma ray detectors; providing a second rack on another side of the vehicle, the second rack including a neutron generator and a plurality of gamma ray detectors; providing a control system, remote from the first and second racks, coupled to the neutron generators and gamma ray detectors; using the control system, causing the neutron generators to generate neutrons; and performing gamma ray spectroscopy on spectra read by the gamma ray detectors to look for a signature indicative of presence of an explosive. Various apparatus and other methods are also provided.

  14. Detecting phonon blockade with photons

    SciTech Connect (OSTI)

    Didier, Nicolas; Pugnetti, Stefano; Fazio, Rosario [NEST, Scuola Normale Superiore and Istituto di Nanoscienze - CNR, Pisa (Italy); Blanter, Yaroslav M. [Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft (Netherlands)

    2011-08-01T23:59:59.000Z

    Measuring the quantum dynamics of a mechanical system, when few phonons are involved, remains a challenge. We show that a superconducting microwave resonator linearly coupled to the mechanical mode constitutes a very powerful probe for this scope. This new coupling can be much stronger than the usual radiation pressure interaction by adjusting a gate voltage. We focus on the detection of phonon blockade, showing that it can be observed by measuring the statistics of the light in the cavity. The underlying reason is the formation of an entangled state between the two resonators. Our scheme realizes a phonotonic Josephson junction, giving rise to coherent oscillations between phonons and photons as well as a self-trapping regime for a coupling smaller than a critical value. The transition from the self-trapping to the oscillating regime is also induced dynamically by dissipation.

  15. Intrusion detection using secure signatures

    DOE Patents [OSTI]

    Nelson, Trent Darnel; Haile, Jedediah

    2014-09-30T23:59:59.000Z

    A method and device for intrusion detection using secure signatures comprising capturing network data. A search hash value, value employing at least one one-way function, is generated from the captured network data using a first hash function. The presence of a search hash value match in a secure signature table comprising search hash values and an encrypted rule is determined. After determining a search hash value match, a decryption key is generated from the captured network data using a second hash function, a hash function different form the first hash function. One or more of the encrypted rules of the secure signatures table having a hash value equal to the generated search hash value are then decrypted using the generated decryption key. The one or more decrypted secure signature rules are then processed for a match and one or more user notifications are deployed if a match is identified.

  16. Methanol detection in M82

    E-Print Network [OSTI]

    S. Martín; J. Martín-Pintado; R. Mauersberger

    2006-03-07T23:59:59.000Z

    We present a multilevel study of the emission of methanol, detected for the first time in this galaxy, and discuss the origin of its emission. The high observed methanol abundance of a few 10^-9 can only be explained if injection of methanol from dust grains is taken into account. While the overall [CH3OH]/[NH3] ratio is much larger than observed towards other starbursts, the dense high excitation component shows a similar value to that found in NGC 253 and Maffei 2. Our observations suggest the molecular material in M 82 to be formed by dense warm cores, shielded from the UV radiation and similar to the molecular clouds in other starbursts, surrounded by a less dense photodissociated halo. The dense warm cores are likely the location of recent and future star formation within M 82.

  17. Detecting torsion from massive electrodynamics

    SciTech Connect (OSTI)

    Garcia de Andrade, L.C.; Lopes, M. (Instituto de Fisica, Rio de Janeiro (Brazil))

    1993-11-01T23:59:59.000Z

    A new method of detecting torsion in the case of massive electrodynamics is proposed. The method is based on the study of spectral lines of hydrogen-like atoms placed in a torsion field, where the interaction energy between the torsion vector field Q and an electric dipole is given by [epsilon] [approximately] p [center dot] Q. All the methods designed so far have been based on spinning test particles interacting with magnetic fields in which the energy splitting is given by [epsilon] [approximately] S [center dot] B on a Stern-Gerlach type experiment. The authors arrive at an energy splitting of order of [epsilon] [approximately] 10[sup [minus]21]erg[approximately]10[sup [minus]9]eV, which is within the frequency band of radio waves. 15 refs.

  18. Detecting temperature fluctuations at equilibrium

    E-Print Network [OSTI]

    Dixit, Purushottam D

    2015-01-01T23:59:59.000Z

    Gibbs and Boltzmann definitions of temperature agree only in the macroscopic limit. The ambiguity in identifying the equilibrium temperature of a finite sized `small' system exchanging energy with a bath is usually understood as a limitation of conventional statistical mechanics. We interpret this ambiguity as resulting from a stochastically fluctuating temperature coupled with the phase space variables giving rise to a broad temperature distribution. With this ansatz, we develop the equilibrium statistics and dynamics of small systems. Numerical evidence using an analytically tractable model shows that the effects of temperature fluctuations can be detected in equilibrium and dynamical properties of the phase space of the small system. Our theory generalizes statistical mechanics to small systems relevant to biophysics and nanotechnology.

  19. Oxygen detection using evanescent fields

    DOE Patents [OSTI]

    Duan, Yixiang (Los Alamos, NM); Cao, Weenqing (Los Alamos, NM)

    2007-08-28T23:59:59.000Z

    An apparatus and method for the detection of oxygen using optical fiber based evanescent light absorption. Methylene blue was immobilized using a sol-gel process on a portion of the exterior surface of an optical fiber for which the cladding has been removed, thereby forming an optical oxygen sensor. When light is directed through the optical fiber, transmitted light intensity varies as a result of changes in the absorption of evanescent light by the methylene blue in response to the oxygen concentration to which the sensor is exposed. The sensor was found to have a linear response to oxygen concentration on a semi-logarithmic scale within the oxygen concentration range between 0.6% and 20.9%, a response time and a recovery time of about 3 s, ant to exhibit good reversibility and repeatability. An increase in temperature from 21.degree. C. to 35.degree. C. does not affect the net absorption of the sensor.

  20. Vertical flow chemical detection portal

    DOE Patents [OSTI]

    Linker, K.L.; Hannum, D.W.; Conrad, F.J.

    1999-06-22T23:59:59.000Z

    A portal apparatus is described for screening objects or persons for the presence of trace amounts of chemical substances such as illicit drugs or explosives. The apparatus has a test space, in which a person may stand, defined by two generally upright sides spanned by a horizontal transom. One or more fans in the transom generate a downward air flow (uni-directional) within the test space. The air flows downwardly from a high pressure upper zone, past the object or person to be screened. Air moving past the object dislodges from the surface thereof both volatile and nonvolatile particles of the target substance. The particles are entrained into the air flow which continues flowing downward to a lower zone of reduced pressure, where the particle-bearing air stream is directed out of the test space and toward preconcentrator and detection components. The sides of the portal are specially configured to partially contain and maintain the air flow. 3 figs.

  1. Mass spectrometry-based methods for detection and differentiation of botulinum neurotoxins

    DOE Patents [OSTI]

    Schmidt, Jurgen G. (Los Alamos, NM); Boyer, Anne E. (Atlanta, GA); Kalb, Suzanne R. (Atlanta, GA); Moura, Hercules (Tucker, GA); Barr, John R. (Suwannee, GA); Woolfitt, Adrian R. (Atlanta, GA)

    2009-11-03T23:59:59.000Z

    The present invention is directed to a method for detecting the presence of clostridial neurotoxins in a sample by mixing a sample with a peptide that can serve as a substrate for proteolytic activity of a clostridial neurotoxin; and measuring for proteolytic activity of a clostridial neurotoxin by a mass spectroscopy technique. In one embodiment, the peptide can have an affinity tag attached at two or more sites.

  2. Active magnetic regenerator

    DOE Patents [OSTI]

    Barclay, John A. (Los Alamos, NM); Steyert, William A. (Los Alamos, NM)

    1982-01-01T23:59:59.000Z

    The disclosure is directed to an active magnetic regenerator apparatus and method. Brayton, Stirling, Ericsson, and Carnot cycles and the like may be utilized in an active magnetic regenerator to provide efficient refrigeration over relatively large temperature ranges.

  3. Selective chemical detection by energy modulation of sensors

    DOE Patents [OSTI]

    Stetter, J.R.; Otagawa, T.

    1985-05-20T23:59:59.000Z

    A portable instrument for use in the field in detecting, identifying, and quantifying a component of a sampled fluid includes a sensor which chemically reacts with the component of interest or a derivative thereof, an electrical heating filament for heating the sample before it is applied to the sensor, and modulating means for continuously varying the temperature of the filament (and hence the reaction rate) between two values sufficient to produce the chemical reaction. In response to this thermal modulation, the sensor produces a modulated output signal, the modulation of which is a function of the activation energy of the chemical reaction, which activation energy is specific to the particular component of interest and its concentration. Microprocessor means compares the modulated output signal with standard responses for a plurality of components to identify and quantify the particular component of interest. 4 figs.

  4. Tissue-based standoff biosensors for detecting chemical warfare agents

    DOE Patents [OSTI]

    Greenbaum, Elias; Sanders, Charlene A.

    2003-11-18T23:59:59.000Z

    A tissue-based, deployable, standoff air quality sensor for detecting the presence of at least one chemical or biological warfare agent, includes: a cell containing entrapped photosynthetic tissue, the cell adapted for analyzing photosynthetic activity of the entrapped photosynthetic tissue; means for introducing an air sample into the cell and contacting the air sample with the entrapped photosynthetic tissue; a fluorometer in operable relationship with the cell for measuring photosynthetic activity of the entrapped photosynthetic tissue; and transmitting means for transmitting analytical data generated by the fluorometer relating to the presence of at least one chemical or biological warfare agent in the air sample, the sensor adapted for deployment into a selected area.

  5. Spot test kit for explosives detection

    DOE Patents [OSTI]

    Pagoria, Philip F; Whipple, Richard E; Nunes, Peter J; Eckels, Joel Del; Reynolds, John G; Miles, Robin R; Chiarappa-Zucca, Marina L

    2014-03-11T23:59:59.000Z

    An explosion tester system comprising a body, a lateral flow membrane swab unit adapted to be removeably connected to the body, a first explosives detecting reagent, a first reagent holder and dispenser operatively connected to the body, the first reagent holder and dispenser containing the first explosives detecting reagent and positioned to deliver the first explosives detecting reagent to the lateral flow membrane swab unit when the lateral flow membrane swab unit is connected to the body, a second explosives detecting reagent, and a second reagent holder and dispenser operatively connected to the body, the second reagent holder and dispenser containing the second explosives detecting reagent and positioned to deliver the second explosives detecting reagent to the lateral flow membrane swab unit when the lateral flow membrane swab unit is connected to the body.

  6. Real-world Polymorphic Attack Detection Michalis Polychronakis,1

    E-Print Network [OSTI]

    Markatos, Evangelos P.

    proposed network-level emulation, a heuristic detection method that scans network traffic to detect, sophisticated obfuscation schemes. Keywords Polymorphism, intrusion detection, code emulation 1. Introduction them under control for as long as possible. As detection mechanisms improve, attackers employ

  7. Gravitational Radiation Detection with Laser Interferometry

    E-Print Network [OSTI]

    Rana X Adhikari

    2014-03-13T23:59:59.000Z

    Gravitational-wave detection has been pursued relentlessly for over 40 years. With the imminent operation of a new generation of laser interferometers, it is expected that detections will become a common occurrence. The research into more ambitious detectors promises to allow the field to move beyond detection and into the realm of precision science using gravitational radiation. In this article, I review the state of the art for the detectors and describe an outlook for the coming decades.

  8. Gravitational Radiation Detection with Laser Interferometry

    E-Print Network [OSTI]

    Adhikari, Rana X

    2013-01-01T23:59:59.000Z

    Gravitational-wave detection has been pursued relentlessly for over 40 years. With the imminent operation of a new generation of laser interferometers, it is expected that detections will become a common occurrence. The research into more ambitious detectors promises to allow the field to move beyond detection and into the realm of precision science using gravitational radiation. In this article, I review the state of the art for the detectors and describe an outlook for the coming decades.

  9. Structural Health Monitoring with Piezoelectric Wafer Active Sensors for Space Applications

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Structural Health Monitoring with Piezoelectric Wafer Active Sensors for Space Applications Adrian detection and structural health monitoring. Where appropriate, comparison between different methods-coupling coefficient I. Introduction STRUCTURAL health monitoring (SHM) is an emerging research area with multiple

  10. Transport Test Problems for Radiation Detection Scenarios

    SciTech Connect (OSTI)

    Shaver, Mark W.; Miller, Erin A.; Wittman, Richard S.; McDonald, Benjamin S.

    2012-09-30T23:59:59.000Z

    This is the final report and deliverable for the project. It is a list of the details of the test cases for radiation detection scenarios.

  11. Detection, Prevention and Mitigation of Cascading Events

    E-Print Network [OSTI]

    disturbances and protective relay operations leading to cascading events. The detection algorithms improved (such as weak connections, unexpected events, hidden failures in protection system, and human errors

  12. Electrochemical detection of leukemia oncogenes using enzyme...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and early disease diagnostic applications. Citation: Lee AC, D Du, B Chen, CK Heng, TM Lim, and Y Lin.2014."Electrochemical detection of leukemia oncogenes using...

  13. Hairpin DNA Switch for Ultrasensitive Spectrophotometric Detection...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hairpin DNA Switch for Ultrasensitive Spectrophotometric Detection of DNA Hybridization Based on Gold Nanoparticles and Enzyme Hairpin DNA Switch for Ultrasensitive...

  14. COLLOQUIUM: Starlight Detectives: How Astronomers, Inventors...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    14, 2015, "Starlight Detectives: How Astronomers, Inventors and Eccentrics Discovered the Modern Universe", Prof. Alan Hirshfeld Colloquium Committee: The Princeton Plasma Physics...

  15. Detection Technologies, Arms control and nonproliferation technologies. Third/fourth quarters 1993

    SciTech Connect (OSTI)

    Staehle, G; Stull, S; Talaber, C; Moulthrop, P [eds.

    1993-12-31T23:59:59.000Z

    This issue of Arms Control and Nonproliferation Technologies is another in a series of issues about specific means for detecting and identifying proliferation and other suspect activities outside the realm of arms control treaties. All the projects discussed are funded by the Office of Research and Development of the Department of Energy`s Office of Nonproliferation and National Security.

  16. Detecting and Defending against Web-Server Fingerprinting Dustin Lee, Jeff Rowe, Calvin Ko, Karl Levitt

    E-Print Network [OSTI]

    California at Davis, University of

    Detecting and Defending against Web-Server Fingerprinting Dustin Lee, Jeff Rowe, Calvin Ko, Karl of web servers and suggests possible defenses to the probing activity. General concepts of finger- printing and their application to the identification of Web servers, even where server information has been

  17. A smart camera application: DSP-based people detection and tracking

    E-Print Network [OSTI]

    Cheng, Victor

    2000-01-01T23:59:59.000Z

    and any camera angle. First an adaptive background subtraction module is used to obtain potential moving target areas. Second a human body detection module is activated to locate the heads. Third a multi-target tracking module is deployed to resolve...

  18. Carbon-on-Metal Films for Surface Plasmon Resonance Detection of Matthew R. Lockett,

    E-Print Network [OSTI]

    Carbon-on-Metal Films for Surface Plasmon Resonance Detection of DNA Arrays Matthew R. Lockett of a lamellar structure in which a thin layer of amorphous carbon is deposited onto a surface plasmon-active gold thin film (Figure 1a). Carbon-based surfaces are readily modified with biomolecules of interest

  19. and solar activity

    E-Print Network [OSTI]

    Memorie Della; K. Georgieva; C. Bianchi; B. Kirov

    Abstract. Solar activity, together with human activity, is considered a possible factor for the global warming observed in the last century. However, in the last decades solar activity has remained more or less constant while surface air temperature has continued to increase, which is interpreted as an evidence that in this period human activity is the main factor for global warming. We show that the index commonly used for quantifying long-term changes in solar activity, the sunspot number, accounts for only one part of solar activity and using this index leads to the underestimation of the role of solar activity in the global warming in the recent decades. A more suitable index is the geomagnetic activity which reflects all solar activity, and it is highly correlated to global temperature variations in the whole period for which we have data. Key words. Solar activity, Global warming 1. Sunspot number and global temperature The most popular index of solar activity is the International sunspot number (R). A reconstruction

  20. Detection of transient fluorine atoms

    SciTech Connect (OSTI)

    Loge, G.W.; Nereson, N.; Fry, H.A.

    1986-01-01T23:59:59.000Z

    A KrF eximer laser with a fluence of 50 mJ/cm/sup 2/ was used to photolyze either uranium hexafluoride or molecular fluorine, yielding a transient number density of fluorine atoms. The rise and decay of the atomic fluorine density was observed by transient absorption of a 25-..mu..m Pb-salt diode laser. To prevent the diode laser wavelength from drifting out of resonance with the atomic fluorine line, part of the beam was split off and sent through a microwave discharge fluorine atom cell. This allowed a wavelength modulation-feedback technique to be used to lock the diode laser wavelength onto the atomic line. The remaining diode laser beam was made collinear with the eximer laser beam using a LiF window with a 45/sup 0/ angle of incidence to reflect the infrared beam while transmitting most of the uv beam. Using this setup along with a transient digitizer to average between 100 and 200 transient absorption profiles, fluorine atom number densities on the order of 10/sup 14/ cm/sup -3/ in a 1.7 m pathlength were detected. The signals observed were about a factor of two less than expected from known photolysis and atomic fluorine absorption cross-sections. 2 refs., 4 figs.

  1. Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors VICTOR of structural damage such as fatigue cracks and corrosion. Two main detection strategies are considered: (a) the wave propagation method for far-field damage detection; and (b) the electro-mechanical (E/M) impedance

  2. Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors VICTOR the onset and progress of structural damage such as fatigue cracks and corrosion. Two main detection strategies are considered: (a) the wave propagation method for far-field damage detection; and (b

  3. Neutron Interrogation System For Underwater Threat Detection And Identification

    SciTech Connect (OSTI)

    Barzilov, Alexander P.; Novikov, Ivan S.; Womble, Phil C. [Department of Physics and Astronomy, Western Kentucky University, 1906 College Heights Blvd, 11077 Bowling Green, KY 42101 (United States)

    2009-03-10T23:59:59.000Z

    Wartime and terrorist activities, training and munitions testing, dumping and accidents have generated significant munitions contamination in the coastal and inland waters in the United States and abroad. Although current methods provide information about the existence of the anomaly (for instance, metal objects) in the sea bottom, they fail to identify the nature of the found objects. Field experience indicates that often in excess of 90% of objects excavated during the course of munitions clean up are found to be non-hazardous items (false alarm). The technology to detect and identify waterborne or underwater threats is also vital for protection of critical infrastructures (ports, dams, locks, refineries, and LNG/LPG). We are proposing a compact neutron interrogation system, which will be used to confirm possible threats by determining the chemical composition of the suspicious underwater object. The system consists of an electronic d-T 14-MeV neutron generator, a gamma detector to detect the gamma signal from the irradiated object and a data acquisition system. The detected signal then is analyzed to quantify the chemical elements of interest and to identify explosives or chemical warfare agents.

  4. Statistical language analysis for automatic exfiltration event detection.

    SciTech Connect (OSTI)

    Robinson, David Gerald

    2010-04-01T23:59:59.000Z

    This paper discusses the recent development a statistical approach for the automatic identification of anomalous network activity that is characteristic of exfiltration events. This approach is based on the language processing method eferred to as latent dirichlet allocation (LDA). Cyber security experts currently depend heavily on a rule-based framework for initial detection of suspect network events. The application of the rule set typically results in an extensive list of uspect network events that are then further explored manually for suspicious activity. The ability to identify anomalous network events is heavily dependent on the experience of the security personnel wading through the network log. Limitations f this approach are clear: rule-based systems only apply to exfiltration behavior that has previously been observed, and experienced cyber security personnel are rare commodities. Since the new methodology is not a discrete rule-based pproach, it is more difficult for an insider to disguise the exfiltration events. A further benefit is that the methodology provides a risk-based approach that can be implemented in a continuous, dynamic or evolutionary fashion. This permits uspect network activity to be identified early with a quantifiable risk associated with decision making when responding to suspicious activity.

  5. Capability of environmental sampling to detect undeclared cask openings

    SciTech Connect (OSTI)

    Beckstead, L.W.; Efurd, D.W.; Hemberger, P.H.; Abhold, M.E.; Eccleston, G.W.

    1997-12-01T23:59:59.000Z

    The goal of this study is to determine the signatures that would allow monitors to detect diversion of nuclear fuel (by a diverter) from a storage area such as a geological repository. Due to the complexity of operations surrounding disposal of spent nuclear fuel in a geologic repository, there are several places that a diversion of fuel could take place. After the canister that contains the fuel rods is breached, the diverter would require a hot cell to process or repackage the fuel. A reference repository and possible diversion scenarios are discussed. When a canister is breached, or during reprocessing to extract nuclear weapons material (primarily Pu), several important isotopes or signatures including tritium, {sup 85}Kr, and {sup 129}I are released to the surrounding environment and have the potential for analysis. Estimates of release concentrations of the key signatures from the repository under a hypothetical diversion scenario are presented and discussed. Gas analysis data collected from above-ground storage casks at Idaho National Engineering and Environmental Laboratory (INEEL) Test Area North (TAN) are included and discussed in the report. In addition, LANL participated in gas sampling of one TAN cask, the Castor V/21, in July 1997. Results of xenon analysis from the cask gas sample are presented and discussed. The importance of global fallout and recent commercial reprocessing activities and their effects on repository monitoring are discussed. Monitoring and instrumental equipment for analysis of the key signature isotopes are discussed along with limits of detection. A key factor in determining if diversion activities are in progress at a repository is the timeliness of detection and analysis of the signatures. Once a clandestine operation is suspected, analytical data should be collected as quickly as possible to support any evidence of diversion.

  6. Active Probing Approach for Fault Localization in Computer Networks*

    E-Print Network [OSTI]

    Sethi, Adarshpal

    to develop tools for performing fault localization. We discuss various design issues involved and propose architecture for building such a tool. We describe an algorithm for probe set selection for problem detection a wide range of activities involving network design and operation [7, 9, 17, 18]. Network monitoring can

  7. Particle Dark Matter and its Detection

    E-Print Network [OSTI]

    Angel Morales

    1998-10-21T23:59:59.000Z

    The status and prospects of the experimental efforts in the detection of Particle Dark Matter is reviewed. Emphasis is put in the direct searches for WIMPs (Weakly Interacting Massive Particles), outlining the various strategies and techniques currently followed and sumarizing the results. A briefing of the indirect methods of WIMP detection is also presented.

  8. Leak detection on an ethylene pipeline

    SciTech Connect (OSTI)

    Hamande, A.; Condacse, V.; Modisette, J.

    1995-12-31T23:59:59.000Z

    A model-based leak detection system has been in operation on the Solvay et Cie ethylene pipeline from Antwerp to Jemeppe on Sambre since 1989. The leak detection system, which is the commercial product PLDS of Modisette Associations, Inc., was originally installed by the supplier. Since 1991, all system maintenance and configuration changes have been done by Solvay et Cie personnel. Many leak tests have been performed, and adjustments have been made in the configuration and the automatic tuning parameters. The leak detection system is currently able to detect leaks of 2 tonnes/hour in 11 minutes with accurate location. Larger leaks are detected in about 2 minutes. Leaks between 0.5 and 1 tonne per hour are detected after several hours. (The nominal mass flow in the pipeline is 15 tonnes/hour, with large fluctuations.) Leaks smaller than 0.5 tonnes per hour are not detected, with the alarm thresholds set at levels to avoid false alarms. The major inaccuracies of the leak detection system appear to be associated with the ethylene temperatures.

  9. Intrusion Detection Techniques in Sensor Aikaterini Mitrokotsa

    E-Print Network [OSTI]

    to the network administrator because communication between the access point and the clients is broadcastPDF PROOF Intrusion Detection Techniques in Sensor Networks Aikaterini Mitrokotsa Department Research has been conducted in wired network Intrusion Detection Systems (IDS) for over 25 years. Although

  10. Radioactive Target Detection Using Wireless Sensor Network

    E-Print Network [OSTI]

    Zhang, Tonglin

    Chapter 31 Radioactive Target Detection Using Wireless Sensor Network Tonglin Zhang Abstract for wireless sensor network data to detect and locate a hidden nuclear target in a large study area. The method assumes multiple radiation detectors have been used as sensor nodes in a wireless sensor network

  11. Distributed Termination Detection for Dynamic Systems

    E-Print Network [OSTI]

    Dhamdhere, Dhananjay Madhav

    Distributed Termination Detection for Dynamic Systems D. M. Dhamdhere \\Lambda Sridhar R. Iyer E for detecting the termination of a dis­ tributed computation is presented. The algorithm does not require global are provided. Keywords Distributed algorithms, Distributed computation, Distributed termination, Dynamic

  12. 8, 22252248, 2008 Detection of oxygen

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ACPD 8, 2225­2248, 2008 Detection of oxygen emission related to spring bloom H. Yamagishi et al Chemistry and Physics Discussions Detection of regional scale sea-to-air oxygen emission related to spring bloom near Japan by using in-situ measurements of atmospheric oxygen/nitrogen ratio H. Yamagishi 1 , Y

  13. Bioluminescent bioreporter integrated circuit detection methods

    DOE Patents [OSTI]

    Simpson, Michael L.; Paulus, Michael J.; Sayler, Gary S.; Applegate, Bruce M.; Ripp, Steven A.

    2005-06-14T23:59:59.000Z

    Disclosed are monolithic bioelectronic devices comprising a bioreporter and an OASIC. These bioluminescent bioreporter integrated circuit are useful in detecting substances such as pollutants, explosives, and heavy-metals residing in inhospitable areas such as groundwater, industrial process vessels, and battlefields. Also disclosed are methods and apparatus for detection of particular analytes, including ammonia and estrogen compounds.

  14. Social Turing Tests: Crowdsourcing Sybil Detection

    E-Print Network [OSTI]

    Wang, Gang; Wilson, Christo; Wang, Xiao; Metzger, Miriam; Zheng, Haitao; Zhao, Ben Y

    2012-01-01T23:59:59.000Z

    As popular tools for spreading spam and malware, Sybils (or fake accounts) pose a serious threat to online communities such as Online Social Networks (OSNs). Today, sophisticated attackers are creating realistic Sybils that effectively befriend legitimate users, rendering existing automated Sybil detection techniques ineffective. In this paper, we explore the feasibility of a crowdsourced Sybil detection system for OSNs. We conduct a large user study on the ability of humans to detect today's Sybil accounts, using a large corpus of ground-truth Sybil accounts from the Facebook and Renren networks. We analyze detection accuracy by both "experts" and "turkers" under a variety of conditions, and find that while turkers vary significantly in their effectiveness, experts consistently produce near-optimal results. These results drive the design of our multi-tier crowdsourcing Sybil detection system. We use trace-driven simulations to show that it is both effective and scalable.

  15. TANG et al.: DETECTION AND TRACKING OF OCCLUDED PEOPLE 1 Detection and Tracking of Occluded People

    E-Print Network [OSTI]

    with many subjects that partially occlude each other. This limitation is due to the fact that current peopleTANG et al.: DETECTION AND TRACKING OF OCCLUDED PEOPLE 1 Detection and Tracking of Occluded People We consider the problem of detection and tracking of multiple people in crowded street scenes. State

  16. POWER SYSTEM LINE OUTAGE DETECTION AND IDENTIFICATION --A QUICKEST CHANGE DETECTION APPROACH

    E-Print Network [OSTI]

    Liberzon, Daniel

    POWER SYSTEM LINE OUTAGE DETECTION AND IDENTIFICATION -- A QUICKEST CHANGE DETECTION APPROACH Department of Electrical and Computer Engineering University of Illinois at Urbana-Champaign ABSTRACT A method to detect and isolate power system transmission line outages in near real-time is proposed

  17. LANSCE | News & Media | Activity Report

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    background News Multimedia Events Profiles Highlights Activity Reports The Pulse User Program Headlines News & Media dotline Activity Reports 2012 2011 LANSCE Activity Report 2012...

  18. Determining root correspondence between previously and newly detected objects

    SciTech Connect (OSTI)

    Paglieroni, David W.; Beer, N Reginald

    2014-06-17T23:59:59.000Z

    A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

  19. Activated carbon aerogels

    SciTech Connect (OSTI)

    Hanzawa, Y.; Kaneko, K. [Chiba Univ. (Japan)] [Chiba Univ. (Japan); Pekala, R.W. [Lawrence Livermore National Lab., CA (United States)] [Lawrence Livermore National Lab., CA (United States); Dresselhaus, M.S. [Massachusetts Inst. of Technology, Cambridge, MA (United States)] [Massachusetts Inst. of Technology, Cambridge, MA (United States)

    1996-12-25T23:59:59.000Z

    Activated carbon aerogels were obtained from the CO{sub 2} activation of the carbon aerogels. The adsorption isotherms of nitrogen on activated carbon aerogels at 77 K were measured and analyzed by the high-resolution {alpha}{sub s} plot to evaluate their porosities. The {alpha}{sub s} plot showed an upward deviation from linearity below {alpha}{sub s} = 0.5, suggesting that the presence of micropores becomes more predominant with the extent of the activation. Activation increased noticeably the pore volume and the surface area (the maximum value: 2600 m{sup 2}.g{sup -1}) without change of the basic network structure of primary particles. Activated carbon aerogels had a bimodal pore size distribution of uniform micropores and mesopores. 16 refs., 2 figs., 1 tab.

  20. PEGylated Liposomal Doxorubicin Targeted to 51-Expressing MDA-MB-231 Breast Cancer Cells

    E-Print Network [OSTI]

    Kokkoli, Efie

    Shroff and Efrosini Kokkoli* Department of Chemical Engineering and Materials Science, University as in vivo. Our current work focuses on designing modified stealth liposomes (liposomes functionalized targeting to the cancer cells. Our results show that PR_b-functionalized stealth liposomes were able

  1. A MDA approach for defining WS-Policy semantic non-functional properties

    E-Print Network [OSTI]

    Belouadha, Fatima-Zahra; Roudies, Ounsa

    2012-01-01T23:59:59.000Z

    A lot of works has been especially interested to the functional aspect of Web services. Nevertheless, it is necessary to describe their non-functional properties such as the security characteristics and the quality of service. The WS-Policy standard was recommended in 2007 to describe Web services policies including the non-functional properties. However, it doesn't provide any information of their meaning necessary for automatic processes. In this paper, we propose a Model Driven Architecture approach founded on W3C standards to generate WSDL language based files including semantic policies. We use a package of WSDL and WS-Policy profiles and transformations rules to generate Web services interfaces files including policies. We extend a XML schema profile according to SAWSDL standard to define semantic non-functional properties domains. This work contributes to minimize the development cost of Web services including semantic policies. Moreover, the generated services can be automatically processed in discove...

  2. The University of Alabama in Huntsville MDA MiDAESS Partners

    E-Print Network [OSTI]

    Alabama in Huntsville, University of

    2) Lead (Company) Contract Number UAH Subcontract Number Domain Booz Allen Hamilton HQ0147-10-D-0018 (Capability Group 6) Booz Allen Hamilton, Inc. HQ0147-10-D-0011 Declassification BMDS Information Assurance) Booz Allen Hamilton HQ0147-11-D-0001 Engineering & Technical Advisory & Analytical Support/Test Mac

  3. Microsoft Word - MDA FINAL FY14 Q1_1_31_14.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1-2014. Management's Discussion & Analysis Profile The Bonneville Power Administration is a federal electric utility based in the Pacific Northwest within the Department of Energy....

  4. Microsoft Word - MDA FINAL FY14 Q1_1_31_14.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHighandSWPA / SPRA / USACE LMI-EFRC Kick-Off Meeting10, 2008Los6333 2.0

  5. NADIR: A prototype system for detecting network and file system abuse

    SciTech Connect (OSTI)

    Hochberg, J.G.; Jackson, K.A.; Stallings, C.A.; McClary, J.F.; DuBois, D.H.; Ford, J.R.

    1992-01-01T23:59:59.000Z

    This paper describes the design of a prototype computer misuse detection system for the Los Alamos Notional Laboratory's Integrated Computing Network (ICN). This automated expert system, the Network Anomaly Detection and Intrusion Reporter (NADIR), streamlines and supplements the manual audit record review traditionally performed by security auditors. NADIR compares network activity, as summarized in weekly profiles of individual users and the ICN as a whole, against expert rules that define security policy, improper or suspicious behavior, and normal user activity. NADIR reports suspicious behavior to security auditors and provides tools to aid in follow-up investigations. This paper describes analysis by NADIR of two types of ICN activity: user authentication and access control, and mass file storage. It highlights system design issues of data handling, exploiting existing auditing systems, and performing audit analysis at the network level.

  6. NADIR: A prototype system for detecting network and file system abuse

    SciTech Connect (OSTI)

    Hochberg, J.G.; Jackson, K.A.; Stallings, C.A.; McClary, J.F.; DuBois, D.H.; Ford, J.R.

    1992-10-01T23:59:59.000Z

    This paper describes the design of a prototype computer misuse detection system for the Los Alamos Notional Laboratory`s Integrated Computing Network (ICN). This automated expert system, the Network Anomaly Detection and Intrusion Reporter (NADIR), streamlines and supplements the manual audit record review traditionally performed by security auditors. NADIR compares network activity, as summarized in weekly profiles of individual users and the ICN as a whole, against expert rules that define security policy, improper or suspicious behavior, and normal user activity. NADIR reports suspicious behavior to security auditors and provides tools to aid in follow-up investigations. This paper describes analysis by NADIR of two types of ICN activity: user authentication and access control, and mass file storage. It highlights system design issues of data handling, exploiting existing auditing systems, and performing audit analysis at the network level.

  7. Methods for radiation detection and characterization using a multiple detector probe

    DOE Patents [OSTI]

    Akers, Douglas William; Roybal, Lyle Gene

    2014-11-04T23:59:59.000Z

    Apparatuses, methods, and systems relating to radiological characterization of environments are disclosed. Multi-detector probes with a plurality of detectors in a common housing may be used to substantially concurrently detect a plurality of different radiation activities and types. Multiple multi-detector probes may be used in a down-hole environment to substantially concurrently detect radioactive activity and contents of a buried waste container. Software may process, analyze, and integrate the data from the different multi-detector probes and the different detector types therein to provide source location and integrated analysis as to the source types and activity in the measured environment. Further, the integrated data may be used to compensate for differential density effects and the effects of radiation shielding materials within the volume being measured.

  8. Alabama Power- UESC Activities

    Broader source: Energy.gov [DOE]

    Presentation—given at the Fall 2012 Federal Utility Partnership Working Group (FUPWG) meeting—discusses Alabama Power and its utility energy service contract (UESC) projects and activities.

  9. Energy Conservation Standards Activities

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Report to Congress August 2014 United States Department of Energy Washington, DC 20585 Energy Conservation Standards Activities Report to Congress | Page i Message from the...

  10. Aging assessment for active fire protection systems

    SciTech Connect (OSTI)

    Ross, S.B. [Science and Engineering Associates, Inc. (United States); Nowlen, S.P.; Tanaka, T. [Sandia National Labs., Albuquerque, NM (United States)

    1995-06-01T23:59:59.000Z

    This study assessed the impact of aging on the performance and reliability of active fire protection systems including both fixed fire suppression and fixed fire detection systems. The experience base shows that most nuclear power plants have an aggressive maintenance and testing program and are finding degraded fire protection system components before a failure occurs. Also, from the data reviewed it is clear that the risk impact of fire protection system aging is low. However, it is assumed that a more aggressive maintenance and testing program involving preventive diagnostics may reduce the risk impact even further.

  11. Activation of fly ash

    DOE Patents [OSTI]

    Corbin, D.R.; Velenyi, L.J.; Pepera, M.A.; Dolhyj, S.R.

    1986-08-19T23:59:59.000Z

    Fly ash is activated by heating a screened magnetic fraction of the ash in a steam atmosphere and then reducing, oxidizing and again reducing the hydrothermally treated fraction. The activated fly ash can be used as a carbon monoxide disproportionating catalyst useful in the production of hydrogen and methane.

  12. Activation of fly ash

    DOE Patents [OSTI]

    Corbin, David R. (New Castle, DE); Velenyi, Louis J. (Lyndhurst, OH); Pepera, Marc A. (Northfield, OH); Dolhyj, Serge R. (Parma, OH)

    1986-01-01T23:59:59.000Z

    Fly ash is activated by heating a screened magnetic fraction of the ash in a steam atmosphere and then reducing, oxidizing and again reducing the hydrothermally treated fraction. The activated fly ash can be used as a carbon monoxide disproportionating catalyst useful in the production of hydrogen and methane.

  13. Fission signal detection using helium-4 gas fast neutron scintillation detectors

    SciTech Connect (OSTI)

    Lewis, J. M., E-mail: lewisj@ufl.edu; Kelley, R. P.; Jordan, K. A. [Nuclear Engineering Program, University of Florida, Gainesville, Florida 32611 (United States); Murer, D. [Arktis Radiation Detectors Ltd., 8045 Zurich (Switzerland)

    2014-07-07T23:59:59.000Z

    We demonstrate the unambiguous detection of the fission neutron signal produced in natural uranium during active neutron interrogation using a deuterium-deuterium fusion neutron generator and a high pressure {sup 4}He gas fast neutron scintillation detector. The energy deposition by individual neutrons is quantified, and energy discrimination is used to differentiate the induced fission neutrons from the mono-energetic interrogation neutrons. The detector can discriminate between different incident neutron energies using pulse height discrimination of the slow scintillation component of the elastic scattering interaction between a neutron and the {sup 4}He atom. Energy histograms resulting from this data show the buildup of a detected fission neutron signal at higher energies. The detector is shown here to detect a unique fission neutron signal from a natural uranium sample during active interrogation with a (d, d) neutron generator. This signal path has a direct application to the detection of shielded nuclear material in cargo and air containers. It allows for continuous interrogation and detection while greatly minimizing the potential for false alarms.

  14. Colorimetric detection of uranium in water

    DOE Patents [OSTI]

    DeVol, Timothy A. (Clemson, SC); Hixon, Amy E. (Piedmont, SC); DiPrete, David P. (Evans, GA)

    2012-03-13T23:59:59.000Z

    Disclosed are methods, materials and systems that can be used to determine qualitatively or quantitatively the level of uranium contamination in water samples. Beneficially, disclosed systems are relatively simple and cost-effective. For example, disclosed systems can be utilized by consumers having little or no training in chemical analysis techniques. Methods generally include a concentration step and a complexation step. Uranium concentration can be carried out according to an extraction chromatographic process and complexation can chemically bind uranium with a detectable substance such that the formed substance is visually detectable. Methods can detect uranium contamination down to levels even below the MCL as established by the EPA.

  15. Detecting persons concealed in a vehicle

    DOE Patents [OSTI]

    Tucker, Jr., Raymond W.

    2005-03-29T23:59:59.000Z

    An improved method for detecting the presence of humans or animals concealed within in a vehicle uses a combination of the continuous wavelet transform and a ratio-based energy calculation to determine whether the motion detected using seismic sensors placed on the vehicle is due to the presence of a heartbeat within the vehicle or is the result of motion caused by external factors such as the wind. The method performs well in the presence of light to moderate ambient wind levels, producing far fewer false alarm indications. The new method significantly improves the range of ambient environmental conditions under which human presence detection systems can reliably operate.

  16. Thermal wake/vessel detection technique

    DOE Patents [OSTI]

    Roskovensky, John K. (Albuquerque, NM); Nandy, Prabal (Albuquerque, NM); Post, Brian N (Albuquerque, NM)

    2012-01-10T23:59:59.000Z

    A computer-automated method for detecting a vessel in water based on an image of a portion of Earth includes generating a thermal anomaly mask. The thermal anomaly mask flags each pixel of the image initially deemed to be a wake pixel based on a comparison of a thermal value of each pixel against other thermal values of other pixels localized about each pixel. Contiguous pixels flagged by the thermal anomaly mask are grouped into pixel clusters. A shape of each of the pixel clusters is analyzed to determine whether each of the pixel clusters represents a possible vessel detection event. The possible vessel detection events are represented visually within the image.

  17. Sensor for detecting changes in magnetic fields

    DOE Patents [OSTI]

    Praeg, W.F.

    1980-02-26T23:59:59.000Z

    A sensor is described for detecting changes in the magnetic field of the equilibrium-field coil of a Tokamak plasma device that comprises a pair of bifilar wires disposed circumferentially, one inside and one outside the equilibrium-field coil. Each is shorted at one end. The difference between the voltages detected at the other ends of the bifilar wires provides a measure of changing flux in the equilibrium-field coil. This difference can be used to detect faults in the coil in time to take action to protect the coil.

  18. Sensor for detecting changes in magnetic fields

    DOE Patents [OSTI]

    Praeg, Walter F. (Palos Park, IL)

    1981-01-01T23:59:59.000Z

    A sensor for detecting changes in the magnetic field of the equilibrium-field coil of a Tokamak plasma device comprises a pair of bifilar wires disposed circumferentially, one inside and one outside the equilibrium-field coil. Each is shorted at one end. The difference between the voltages detected at the other ends of the bifilar wires provides a measure of changing flux in the equilibrium-field coil. This difference can be used to detect faults in the coil in time to take action to protect the coil.

  19. High sensitivity leak detection method and apparatus

    DOE Patents [OSTI]

    Myneni, G.R.

    1994-09-06T23:59:59.000Z

    An improved leak detection method is provided that utilizes the cyclic adsorption and desorption of accumulated helium on a non-porous metallic surface. The method provides reliable leak detection at superfluid helium temperatures. The zero drift that is associated with residual gas analyzers in common leak detectors is virtually eliminated by utilizing a time integration technique. The sensitivity of the apparatus of this disclosure is capable of detecting leaks as small as 1 [times] 10[sup [minus]18] atm cc sec[sup [minus]1]. 2 figs.

  20. High sensitivity leak detection method and apparatus

    DOE Patents [OSTI]

    Myneni, Ganapatic R. (Grafton, VA)

    1994-01-01T23:59:59.000Z

    An improved leak detection method is provided that utilizes the cyclic adsorption and desorption of accumulated helium on a non-porous metallic surface. The method provides reliable leak detection at superfluid helium temperatures. The zero drift that is associated with residual gas analyzers in common leak detectors is virtually eliminated by utilizing a time integration technique. The sensitivity of the apparatus of this disclosure is capable of detecting leaks as small as 1.times.10.sup.-18 atm cc sec.sup.-1.

  1. Method for remote detection of trace contaminants

    DOE Patents [OSTI]

    Simonson, Robert J.; Hance, Bradley G.

    2003-09-09T23:59:59.000Z

    A method for remote detection of trace contaminants in a target area comprises applying sensor particles that preconcentrate the trace contaminant to the target area and detecting the contaminant-sensitive fluorescence from the sensor particles. The sensor particles can have contaminant-sensitive and contaminant-insensitive fluorescent compounds to enable the determination of the amount of trace contaminant present in the target are by relative comparison of the emission of the fluorescent compounds by a local or remote fluorescence detector. The method can be used to remotely detect buried minefields.

  2. Integrated nuclear techniques to detect illicit materials

    SciTech Connect (OSTI)

    DeVolpi, A.

    1997-10-01T23:59:59.000Z

    This paper discusses the problem of detecting explosives in the context of an object being transported for illicit purposes. The author emphasizes that technologies developed for this particular application have payoffs in many related problem areas. The author discusses nuclear techniques which can be applied to this detection problem. These include: x-ray imaging; neutronic interrogation; inelastic neutron scattering; fieldable neutron generators. He discusses work which has been done on the applications of these technologies, including results for detection of narcotics. He also discusses efforts to integrate these techniques into complementary systems which offer improved performance.

  3. Selective chemical detection by energy modulation of sensors

    DOE Patents [OSTI]

    Stetter, Joseph R. (Naperville, IL); Otagawa, Takaaki (Solon, OH)

    1991-01-01T23:59:59.000Z

    A portable instrument for use in the field in detecting, identifying, and quantifying a component of a sampled fluid includes a sensor which chemically reacts with the component of interest or a derivative thereof, an electrical heating filament for heating the sample before it is applied to the sensor, and modulator for continuously varying the temperature of the filament (and hence the reaction rate) between two values sufficient to produce the chemical reaction. In response to this thermal modulation, the sensor produces a modulated output signal, the modulation of which is a function of the activation energy of the chemical reaction, which activation energy is specific to the particular component of interest and its concentration. Microprocessor which compares the modulated output signal with standard responses for a plurality of components to identify and quantify the particular component of interest. In particular, the concentration of the component of interest is proportional to the amplitude of the modulated output signal, while the identifying activation output energy of the chemical interaction indicative of that component is proportional to a normalized parameter equal to the peak-to-peak amplitude divided by the height of the upper peaks above a base line signal level.

  4. Selective chemical detection by energy modulation of sensors

    DOE Patents [OSTI]

    Stetter, J.R.; Otagawa, T.

    1991-09-10T23:59:59.000Z

    A portable instrument for use in the field in detecting, identifying, and quantifying a component of a sampled fluid includes a sensor which chemically reacts with the component of interest or a derivative thereof, an electrical heating filament for heating the sample before it is applied to the sensor, and modulator for continuously varying the temperature of the filament (and hence the reaction rate) between two values sufficient to produce the chemical reaction. In response to this thermal modulation, the sensor produces a modulated output signal, the modulation of which is a function of the activation energy of the chemical reaction, which activation energy is specific to the particular component of interest and its concentration. Microprocessor which compares the modulated output signal with standard responses for a plurality of components to identify and quantify the particular component of interest. In particular, the concentration of the component of interest is proportional to the amplitude of the modulated output signal, while the identifying activation output energy of the chemical interaction indicative of that component is proportional to a normalized parameter equal to the peak-to-peak amplitude divided by the height of the upper peaks above a base line signal level. 5 figures.

  5. Electrochemical detection of leukemia oncogenes using enzyme-loaded carbon nanotube labels

    SciTech Connect (OSTI)

    Lee, Ai Cheng; Du, Dan; Chen, Baowei; Heng, Chew-Kiat; Lim, Tit-Meng; Lin, Yuehe

    2014-09-07T23:59:59.000Z

    Here we describe an ultrasensitive electrochemical nucleic acids assay amplified by carbon nanotubes (CNTs)-based labels for the detection of human acute lymphocytic leukemia (ALL) related p185 BCR-ABL fusion transcript. The carboxylated CNTs were functionalized with horseradish peroxidase (HRP) molecules and target-specific detection probes (DP) via diimide-activated amidation, and used to label and amplify target hybridization signal. The activity of captured HRP was monitored by square-wave voltammetry measuring the electroactive enzymatic product in the presence of 2-aminophenol and hydrogen peroxide substrate solution. The effect of DP and HRP loading of the CNT-based labels on its signal-to-noise ratio of electrochemical detection was studied systematically for the first time. Under optimized conditions, the signal-amplified assay achieved a detection limit of 83 fM targets oligonuecleotides and a 4-order wide dynamic range of target concentration. The resulting assay allowed a robust discrimination between the perfect match and a three-base mismatch sequence. When subjected to full-length (491 bp) DNA oncogene, the approach demonstrated a detection limit of approximately 33 pg of the target gene. The high sensitivity and specificity of assay enabled PCR-free detection of target transcripts in as little as 65 ng of mRNA extracted from positive ALL cell lines SUP-B15, in comparison to those obtained from negative cell lines HL-60. The approach holds promise for simple, low cost and ultrasensitive electrochemical nucleic acids detection in portable devices, point-of-care and early disease diagnostic applications.

  6. Advanced Review Use of models in detection

    E-Print Network [OSTI]

    , Edinburgh, UK 2Pacific Climate Impacts Consortium, University of Victoria, Victoria, British Columbia John Wiley & Sons, Ltd. Volume 2, July/August 2011 #12;WIREs Climate Change Models in detection

  7. Calibration robust entanglement detection beyond Bell inequalities

    E-Print Network [OSTI]

    Tobias Moroder; Oleg Gittsovich

    2011-11-25T23:59:59.000Z

    In its vast majority entanglement verification is examined either in the complete characterized or totally device independent scenario. The assumptions imposed by these extreme cases are often either too weak or strong for real experiments. Here we investigate this detection task for the intermediate regime where partial knowledge of the measured observables is known, considering cases like orthogonal, sharp or only dimension bounded measurements. We show that for all these assumptions it is not necessary to violate a corresponding Bell inequality in order to detect entanglement. We derive strong detection criteria that can be directly evaluated for experimental data and which are robust against large classes of calibration errors. The conditions are even capable of detecting bound entanglement under the sole assumption of dimension bounded measurements.

  8. Detecting open surfaces in three dimensions

    E-Print Network [OSTI]

    Bose, Biswajit, 1981-

    2009-01-01T23:59:59.000Z

    We present a novel level-set method for representing and detecting open surfaces embedded in three-dimensional image volumes. Open surfaces are two-dimensional manifolds with a one-dimensional boundary lying within a ...

  9. Nanofluidic biosensing for beta-amyloid detection 

    E-Print Network [OSTI]

    Chou, I-Hsien

    2009-05-15T23:59:59.000Z

    A nanofluidic biosensor using surface-enhanced Raman scattering (SERS) was developed to detect the ?-amyloid (A?) protein, one of the biomarkers of Alzheimer’s disease (AD). Recent studies have indicated that investigating changes in relative...

  10. Laser technique detects pollutants in fish

    SciTech Connect (OSTI)

    Krause, C.

    1992-01-01T23:59:59.000Z

    Using a laser and a mass spectrometer, trace pollutants can be detected in fish scales and the time and place of exposure can be determined. The technique has been demonstrated using striped bass from the Clinch and Tennessee rivers.

  11. Detection of arcs in automotive electrical systems

    E-Print Network [OSTI]

    Mishrikey, Matthew David

    2005-01-01T23:59:59.000Z

    At the present time, there is no established method for the detection of DC electric arcing. This is a concern for forthcoming advanced automotive electrical systems which consist of higher DC electric power bus voltages, ...

  12. Sensitive electrochemical detection of horseradish peroxidase...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    devices and point-of-care (POC) diagnosis applications. Citation: Lee AC, G Liu, CK Heng, SN Tan, TM Lim, and Y Lin.2008."Sensitive electrochemical detection of horseradish...

  13. Quantitative spectroscopy for detection of cervical dysplasia

    E-Print Network [OSTI]

    Mirkovi?, Jelena, Ph. D. Massachusetts Institute of Technology

    2009-01-01T23:59:59.000Z

    The current clinical standard for cervical cancer diagnosis is colposcopy, a procedure that involves visual inspection and biopsy of at-risk tissue, followed by histopathology. The major objective of colposcopy is detection ...

  14. Toward automated detection of malignant melanoma

    E-Print Network [OSTI]

    Gareau, Daniel S.

    In vivo reflectance confocal microscopy shows promise for the early detection of malignant melanoma (MM). Two hallmarks of MM have been identified: the presence of pagetoid melanocytes in the epidermis and the breakdown ...

  15. Detecting cosmic rays of the highest energies

    E-Print Network [OSTI]

    F. Vannucci

    2001-06-06T23:59:59.000Z

    Charged cosmic rays have been measured up to macroscopic energies. Concerning neutrinos, the detection is still limited to terrestrial ones (apart from supernova production). A new way to search for extragalactic neutrinos is discussed.

  16. Nondestructive Damage Detection in General Beams

    E-Print Network [OSTI]

    Dincal, Selcuk

    2010-12-08T23:59:59.000Z

    is also vital for a nation’s economy. Substantial sums of money may be saved upon detecting structural deterioration in a timely manner. Nondestructive damage evaluation (NDE) offers effective and economically feasible solutions to perform such tasks...

  17. Sensor Fault Detection and Isolation System

    E-Print Network [OSTI]

    Yang, Cheng-Ken

    2014-08-01T23:59:59.000Z

    The purpose of this research is to develop a Fault Detection and Isolation (FDI) system which is capable to diagnosis multiple sensor faults in nonlinear cases. In order to lead this study closer to real world applications in oil industries...

  18. Slow speed object detection for haul trucks

    SciTech Connect (OSTI)

    NONE

    2009-09-15T23:59:59.000Z

    Caterpillar integrates radar technology with its current camera based system. Caterpillar has developed the Integrated Object Detection System, a slow speed object detection system for mining haul trucks. Object detection is a system that aids the truck operator's awareness of their surroundings. The system consists of a color touch screen display along with medium- and short-range radar as well as cameras, harnesses and mounting hardware. It is integrated into the truck's Work Area Vision System (WAVS). After field testing in 2007, system commercialization began in 2008. Prototype systems are in operation in Australia, Utah and Arizona and the Integrated Object Detection System will be available in the fourth quarter of 2009 and on production trucks 785C, 789C, 793D and 797B. The article is adapted from a presentation by Mark Richards of Caterpillar to the Haulage & Loading 2009 conference, May, held in Phoenix, AZ. 1 fig., 5 photos.

  19. Exploiting weather forecast data for cloud detection 

    E-Print Network [OSTI]

    Mackie, Shona

    2009-01-01T23:59:59.000Z

    Accurate, fast detection of clouds in satellite imagery has many applications, for example Numerical Weather Prediction (NWP) and climate studies of both the atmosphere and of the Earth’s surface temperature. Most ...

  20. Nanofluidic biosensing for beta-amyloid detection

    E-Print Network [OSTI]

    Chou, I-Hsien

    2009-05-15T23:59:59.000Z

    A nanofluidic biosensor using surface-enhanced Raman scattering (SERS) was developed to detect the ?-amyloid (A?) protein, one of the biomarkers of Alzheimer’s disease (AD). Recent studies have indicated that investigating changes in relative...

  1. Verilogo : proactive phishing detection via logo recognition

    E-Print Network [OSTI]

    Wang, Ge

    2010-01-01T23:59:59.000Z

    6.1 Issues with logo matching 6.2 Possible evasionChapter 3 Logo-based phishing detection . . . 3.1 ThreatThe CNN logo is displayed in the green box and a non-CNN

  2. Propagation of guided Lamb waves in bonded specimens using piezoelectric wafer active sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Propagation of guided Lamb waves in bonded specimens using piezoelectric wafer active sensors and principles used for generation and propagation of ultrasonic guided waves (Lamb waves) using piezoelectric wafer active sensors (PWAS). Keywords: Ultrasonic, Lamb waves, Damage detection, NDE, Wave propagation

  3. Recognizing Human Activities from Multi-Modal Shu Chen,Yan Huang

    E-Print Network [OSTI]

    Huang, Yan

    and used in our experiments can also be accessed online. II. RELATED WORK Automatic human activities and experiments are not provided in their paper. Joshua et al. [5] use RFID-based tech- niques to detect humanRecognizing Human Activities from Multi-Modal Sensors Shu Chen,Yan Huang Department of Computer

  4. Design and Fabrication of Cherenkov Counters for the Detection of SNM

    SciTech Connect (OSTI)

    Erickson, Anna S.; Lanza, Richard [Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139 (United States); Galaitsis, Anthony; Hynes, Michael; Blackburn, Brandon [Raytheon IDS, 50 Apple Hill Drive, Tewksbury, MA 01876 (United States); Bernstein, Adam [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 (United States)

    2011-12-13T23:59:59.000Z

    The need for large-size detectors for long-range active interrogation (AI) detection of SNM has generated interest in water-based detector technologies. Water Cherenkov Detectors (WCD) were selected for this research because of their transportability, scalability, and an inherent energy threshold. The detector design and analysis was completed using the Geant4 toolkit. It was demonstrated both computationally and experimentally that it is possible to use WCD to detect and characterize gamma rays. Absolute efficiency of the detector (with no energy cuts applied) was determined to be around 30% for a {sup 60}Co source.

  5. Neutron counter based on beryllium activation

    SciTech Connect (OSTI)

    Bienkowska, B.; Prokopowicz, R.; Kaczmarczyk, J.; Paducha, M. [Institute of Plasma Physics and Laser Microfusion (IPPLM), Hery 23, 01-497 Warsaw (Poland); Scholz, M.; Igielski, A. [Institute of Nuclear Physics PAS (IFJPAN), Radzikowskiego 152, 31-342 Krakow (Poland); Karpinski, L. [Faculty of Electrical Engineering, Rzeszow University of Technology, Pola 2, 35-959 Rzeszow (Poland); Pytel, K. [National Centre for Nuclear Research (NCBJ), Soltana 7, 05-400 Otwock - Swierk (Poland)

    2014-08-21T23:59:59.000Z

    The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction {sup 9}Be(n, ?){sup 6}He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, {sup 6}He, decays with half-life T{sub 1/2} = 0.807 s emitting ?{sup ?} particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of ?–particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known ?–source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5–the Monte Carlo transport code. It allowed proper application of the results of transport calculations of ?{sup ?} particles emitted from radioactive {sup 6}He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

  6. Active optical zoom system

    DOE Patents [OSTI]

    Wick, David V.

    2005-12-20T23:59:59.000Z

    An active optical zoom system changes the magnification (or effective focal length) of an optical imaging system by utilizing two or more active optics in a conventional optical system. The system can create relatively large changes in system magnification with very small changes in the focal lengths of individual active elements by leveraging the optical power of the conventional optical elements (e.g., passive lenses and mirrors) surrounding the active optics. The active optics serve primarily as variable focal-length lenses or mirrors, although adding other aberrations enables increased utility. The active optics can either be LC SLMs, used in a transmissive optical zoom system, or DMs, used in a reflective optical zoom system. By appropriately designing the optical system, the variable focal-length lenses or mirrors can provide the flexibility necessary to change the overall system focal length (i.e., effective focal length), and therefore magnification, that is normally accomplished with mechanical motion in conventional zoom lenses. The active optics can provide additional flexibility by allowing magnification to occur anywhere within the FOV of the system, not just on-axis as in a conventional system.

  7. Intrusion detection in mobile ad hoc networks

    E-Print Network [OSTI]

    Sun, Bo

    2005-08-29T23:59:59.000Z

    .Zone-BasedIntrusionDetectionSystem(ZBIDS)...... 25 1. ZBIDSFramework.................... 25 D.InternalModeloftheIDSAgent............... 29 1. DataCollectionModule................. 30 2. DetectionEngine..................... 31 3. Local Aggregation and Correlation Engine (LACE) . . 32 4. Global... have been widely regarded as being part of the solution to protect today?s computer systems. Research on IDSs began with a report by Anderson [9] followed by Denning?s seminal paper [10], which lays the foundation for most of the current intrusion...

  8. Wireless sensor for detecting explosive material

    DOE Patents [OSTI]

    Lamberti, Vincent E; Howell, Jr., Layton N; Mee, David K; Sepaniak, Michael J

    2014-10-28T23:59:59.000Z

    Disclosed is a sensor for detecting explosive devices. The sensor includes a ferromagnetic metal and a molecular recognition reagent coupled to the ferromagnetic metal. The molecular recognition reagent is operable to expand upon absorption of vapor from an explosive material such that the molecular recognition reagent changes a tensile stress upon the ferromagnetic metal. The explosive device is detected based on changes in the magnetic switching characteristics of the ferromagnetic metal caused by the tensile stress.

  9. Apparatus and methods for detecting chemical permeation

    DOE Patents [OSTI]

    Vo-Dinh, Tuan (Knoxville, TN)

    1994-01-01T23:59:59.000Z

    Apparatus and methods for detecting the permeation of hazardous or toxic chemicals through protective clothing are disclosed. The hazardous or toxic chemicals of interest do not possess the spectral characteristic of luminescence. The apparatus and methods utilize a spectrochemical modification technique to detect the luminescence quenching of an indicator compound which upon permeation of the chemical through the protective clothing, the indicator is exposed to the chemical, thus indicating chemical permeation.

  10. Cyber Security Audit and Attack Detection Toolkit

    SciTech Connect (OSTI)

    Peterson, Dale

    2012-05-31T23:59:59.000Z

    This goal of this project was to develop cyber security audit and attack detection tools for industrial control systems (ICS). Digital Bond developed and released a tool named Bandolier that audits ICS components commonly used in the energy sector against an optimal security configuration. The Portaledge Project developed a capability for the PI Historian, the most widely used Historian in the energy sector, to aggregate security events and detect cyber attacks.

  11. Active Optics and Coronography with the Hubble Space Telescope

    E-Print Network [OSTI]

    Fabien Malbet; Michael Shao; Jeffrey Yu

    1994-04-12T23:59:59.000Z

    In the field of planet and proto-planetary disk detection, achieving high angular resolution and high dynamic range is a necessity. Coronography coupled with adaptive optics on Hubble Space Telescope is a way to get both good spatial resolution and high dynamic range. However, because of the residual figure errors on the primary and on the secondary, HST has a scattered light level that prevents it from detecting extra-solar planets. Our simulations show that by using an active mirror (400-1000 actuators) in the optical path of HST with adaptive optics, we can correct the mirror errors and decrease the scattering level by a factor $10^{2}$ (from $10^{-4}$ to $10^{-6}$ fainter than the star). Furthermore, by controlling the spatial frequencies of the active mirror with a {\\em dark hole\\/} algorithm we can decrease the scattering level in image zones where planet detection is likely. Using this technique, we have succeeded in decreasing the scattering level to $3\\times 10^{-8}$ of the star intensity within 1 arcsec from the central star. This will allow the detection of a Jupiter-like planet $10^{-9}$ times dimmer than the central star located 10 pc away in 1 hour of integration time with a signal-to-noise ratio of 5. This paper describes the method used to determine the actuator strokes applied to a deformable mirror to achieve planet detection and the design of a coronograph which implements this novel technique.

  12. Acoustic resonance for nonmetallic mine detection

    SciTech Connect (OSTI)

    Kercel, S.W.

    1998-04-01T23:59:59.000Z

    The feasibility of acoustic resonance for detection of plastic mines was investigated by researchers at the Oak Ridge National Laboratory`s Instrumentation and Controls Division under an internally funded program. The data reported in this paper suggest that acoustic resonance is not a practical method for mine detection. Representative small plastic anti-personnel mines were tested, and were found to not exhibit detectable acoustic resonances. Also, non-metal objects known to have strong acoustic resonances were tested with a variety of excitation techniques, and no practical non-contact method of exciting a consistently detectable resonance in a buried object was discovered. Some of the experimental data developed in this work may be useful to other researchers seeking a method to detect buried plastic mines. A number of excitation methods and their pitfalls are discussed. Excitation methods that were investigated include swept acoustic, chopped acoustic, wavelet acoustic, and mechanical shaking. Under very contrived conditions, a weak response that could be attributed to acoustic resonance was observed, but it does not appear to be practical as a mine detection feature. Transfer properties of soil were investigated. Impulse responses of several representative plastic mines were investigated. Acoustic leakage coupling, and its implications as a disruptive mechanism were investigated.

  13. PRESSURE ACTIVATED SEALANT TECHNOLOGY

    SciTech Connect (OSTI)

    Michael A. Romano

    2004-04-01T23:59:59.000Z

    The objective of this project is to develop new, efficient, cost effective methods of internally sealing natural gas pipeline leaks through the application of differential pressure activated sealants. In researching the current state of the art for gas pipeline sealing technologies we concluded that if the project was successful, it appeared that pressure activated sealant technology would provide a cost effective alternative to existing pipeline repair technology. From our analysis of current field data for a 13 year period from 1985 to 1997 we were able to identify 205 leaks that were candidates for pressure activated sealant technology, affirming that pressure activated sealant technology is a viable option to traditional external leak repairs. The data collected included types of defects, areas of defects, pipe sizes and materials, incident and operating pressures, ability of pipeline to be pigged and corrosion states. This data, and subsequent analysis, was utilized as a basis for constructing applicable sealant test modeling.

  14. Focused active inference

    E-Print Network [OSTI]

    Levine, Daniel S., Ph. D. Massachusetts Institute of Technology

    2014-01-01T23:59:59.000Z

    In resource-constrained inferential settings, uncertainty can be efficiently minimized with respect to a resource budget by incorporating the most informative subset of observations - a problem known as active inference. ...

  15. Active terahertz metamaterials

    SciTech Connect (OSTI)

    Chen, Hou-tong [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    We demonstrate planar terahertz metamaterial devices enabling actively controllable transmission amplitude, phase, or frequency at room temperature via carrier depletion or photoexcitation in the semiconductor substrate or in semiconductor materials incorporated into the metamaterial structure.

  16. Pulsed Photofission Delayed Gamma Ray Detection for Nuclear Material Identification

    SciTech Connect (OSTI)

    John Kavouras; Xianfei Wen; Daren R. Norman; Dante R. Nakazawa; Haori Yang

    2012-11-01T23:59:59.000Z

    Innovative systems with increased sensitivity and resolution are in great demand to detect diversion and to prevent misuse in support of nuclear materials management for the U.S. fuel cycle. Nuclear fission is the most important multiplicative process involved in non-destructive active interrogation. This process produces the most easily recognizable signature for nuclear materials. High-energy gamma rays can also excite a nucleus and cause fission through a process known as photofission. After photofission reactions, delayed signals are easily distinguishable from the interrogating radiation. Linac-based, advanced inspection techniques utilizing the fission signals after photofission have been extensively studied for homeland security applications. Previous research also showed that a unique delayed gamma ray energy spectrum exists for each fissionable isotope. Isotopic composition measurement methods based on delayed gamma ray spectroscopy will be the primary focus of this work.

  17. Low activation ferritic alloys

    DOE Patents [OSTI]

    Gelles, D.S.; Ghoniem, N.M.; Powell, R.W.

    1985-02-07T23:59:59.000Z

    Low activation ferritic alloys, specifically bainitic and martensitic stainless steels, are described for use in the production of structural components for nuclear fusion reactors. They are designed specifically to achieve low activation characteristics suitable for efficient waste disposal. The alloys essentially exclude molybdenum, nickel, nitrogen and niobium. Strength is achieved by substituting vanadium, tungsten, and/or tantalum in place of the usual molybdenum content in such alloys.

  18. Low activation ferritic alloys

    DOE Patents [OSTI]

    Gelles, David S. (West Richland, WA); Ghoniem, Nasr M. (Granada Hills, CA); Powell, Roger W. (Pasco, WA)

    1986-01-01T23:59:59.000Z

    Low activation ferritic alloys, specifically bainitic and martensitic stainless steels, are described for use in the production of structural components for nuclear fusion reactors. They are designed specifically to achieve low activation characteristics suitable for efficient waste disposal. The alloys essentially exclude molybdenum, nickel, nitrogen and niobium. Strength is achieved by substituting vanadium, tungsten, and/or tantalum in place of the usual molybdenum content in such alloys.

  19. Defect Prevention and Detection in Software for Automated Test Equipment

    SciTech Connect (OSTI)

    E. Bean

    2006-11-30T23:59:59.000Z

    Software for automated test equipment can be tedious and monotonous making it just as error-prone as other software. Active defect prevention and detection are also important for test applications. Incomplete or unclear requirements, a cryptic syntax used for some test applications—especially script-based test sets, variability in syntax or structure, and changing requirements are among the problems encountered in one tester. Such problems are common to all software but can be particularly problematic in test equipment software intended to test another product. Each of these issues increases the probability of error injection during test application development. This report describes a test application development tool designed to address these issues and others for a particular piece of test equipment. By addressing these problems in the development environment, the tool has powerful built-in defect prevention and detection capabilities. Regular expressions are widely used in the development tool as a means of formally defining test equipment requirements for the test application and verifying conformance to those requirements. A novel means of using regular expressions to perform range checking was developed. A reduction in rework and increased productivity are the results. These capabilities are described along with lessons learned and their applicability to other test equipment software. The test application development tool, or “application builder”, is known as the PT3800 AM Creation, Revision and Archiving Tool (PACRAT).

  20. Detection of CO sub 2 -Induced climatic change

    SciTech Connect (OSTI)

    Wigley, T.M.L.; Jones, P.D.

    1989-08-15T23:59:59.000Z

    We will assemble and analyse instrumental climate data and to develop simple climate models as a basis for (1) detecting greenhouse-gas-induced climatic change, and (2) validation of General Circulation Models. In addition to variations in greenhouse gas concentrations, climate responds to a number of other forcing factors, changes in ocean circulation, volcanic activity, solar irradiance, etc. To detect the greenhouse effect, its signal must be isolated from the noise'' of natural climatic variability, a significant part of which is due to these other factors. A high quality, spatially extensive data base is required to define the noise and its spatial characteristics. Available land and marine data bases will updated and expanded, and differences between different data sets will be reconciled where possible. The data will be analysed to determine the potential effects on climate of greenhouse gas concentration changes and other factors. Analyses will be guided by simple energy balance climate models. These analyses are oriented toward obtaining early evidence of greenhouse-gas-induced climatic change that would lead either to confirmation, rejection or modification of model projections, and toward the statistical validation of General Circulation Model control runs. 23 refs., 4 figs.

  1. NSLS 2009 Activity Report

    SciTech Connect (OSTI)

    Nasta K.; Mona R.

    2009-05-01T23:59:59.000Z

    2009 was an incredibly exciting year for light sources at Brookhaven. The National Synchrotron Light Source (NSLS) hosted more than 2,200 visiting researchers, who, along with the about 50 members of our scientific staff, produced a total of 957 publications - about 20 percent of which appeared in premier journals. Covering topics ranging from Alzheimer's disease detection to ethanol-powered fuel cells, a sampling of these findings can be found in this Activity Report. We've also seen the resurfacing of some of our long-time users hard work. I was very proud to hear that two of the three recipients of the 2009 Nobel Prize in Chemistry have ties to the NSLS. Venki Ramakrishnan, a former employee in Brookhaven's biology department and long-time user of the NSLS, now at Cambridge University, and Thomas A. Steitz of Yale University, also a long-time NSLS user, shared the prize with Ada E. Yonath of the Weizmann Institute of Science for their work on the structure and function of the ribosome. In the late 1990s, Ramakrishnan and Steitz used protein crystallography at the NSLS to gather atomic-level images of two ribosome subunits: 30S (Ramakrishnan) and 50S (Steitz). Both laureates solved the high-resolution structures for these subunits based on this data. After struggling with a rough budget for several years, we received excellent funding, and then some, this year. In addition to NSLS operations funding, we received $3 million in funds from the American Recovery and Reinvestment Act (ARRA). We used that additional money for two exciting projects: construction of a full-field x-ray microscope and acquisition of several advanced x-ray detectors. The x-ray microscope will be able to image objects with a targeted spatial resolution of 30 nanometers. This capability will be particularly important for new initiatives in energy research and will prepare our users for the projected 1-nanometer resolution benchmark at the National Synchrotron Light Source II (NSLS-II). The detectors project is expected to increase the throughput of several high-demand beamlines by an order of magnitude as well as enable new classes of experiments. In addition, a huge chunk of ARRA money - $150 million - was put toward accelerating the construction of NSLS-II, which is now taking shape across the street. Now physically much more than just a pile of dirt, NSLS-II was granted Critical Decision 3 status by the Department of Energy (DOE) early last year, giving the official go-ahead for construction. In July, construction began, marked by a groundbreaking ceremony that attracted elected officials, media, and DOE, Battelle, and Stony Brook University representatives from across the state and the country. As progress on NSLS-II continues, we're working with Stony Brook University to identify ways to capitalize on the facility's unique capabilities through the Joint Photon Sciences Institute (JPSI). Included in this effort is a series of workshops to encourage the development and application of the photon sciences with collaborative research between industries, universities, and national laboratories. We helped host three of these workshops this year, focusing on microelectronics, energy storage, and materials in next-generation energy systems. The conversation and ideas generated at these meetings has been fresh and valuable and we hope to use this model to organize research opportunities in other scientific fields. Also this year: Brookhaven was deemed the lead institution for one of DOE's 46 Energy Frontier Research Centers, focused on understanding the underlying nature of superconductivity in complex materials by using techniques at the NSLS and CFN; DOE awarded a $100,000 supplemental grant to our detector program to continue the development of a new generation of x-ray detectors that use germanium sensors, which, at high energies, are much more efficient than equivalent ones based on silicon; and funding for one of our largest consortia, Case Western Reserve University's Center for Synchrotron Biosciences (CSB), was renewed through the National Inst

  2. EECBG Success Story: Energy Detectives Help Pennsylvania Town...

    Energy Savers [EERE]

    Energy Detectives Help Pennsylvania Town Reduce Costs EECBG Success Story: Energy Detectives Help Pennsylvania Town Reduce Costs July 23, 2010 - 3:24pm Addthis Judith Mondre meets...

  3. animal detection system: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Channel Fault Detection and Diagnosis System for a Small Animal APD-Based Digital PET Scanner CERN Preprints Summary: Fault detection and diagnosis is critical to many...

  4. Detecting Fractures Using Technology at High Temperatures and...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Detecting Fractures Using Technology at High Temperatures and Depths - Geothermal Ultrasonic Fracture Imager (GUFI); 2010 Geothermal Technology Program Peer Review Report Detecting...

  5. A graphene-based electrochemical sensor for sensitive detection...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A graphene-based electrochemical sensor for sensitive detection of paracetamol . A graphene-based electrochemical sensor for sensitive detection of paracetamol . Abstract: An...

  6. A different Big Bang theory: Los Alamos unveils explosives detection...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    unveils explosives detection expertise A different Big Bang theory: Los Alamos unveils explosives detection expertise A team of scientists is now rolling out a collaborative...

  7. An Infrared Spectral Database for Detection of Gases Emitted...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Database for Detection of Gases Emitted by Biomass Burning. An Infrared Spectral Database for Detection of Gases Emitted by Biomass Burning. Abstract: We report the construction of...

  8. A graphene-based electrochemical sensor for sensitive detection...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    graphene-based electrochemical sensor for sensitive detection of paracetamol . A graphene-based electrochemical sensor for sensitive detection of paracetamol . Abstract: An...

  9. Damage Detection in Plate Structures using Guided Ultrasonic Waves

    E-Print Network [OSTI]

    Jarmer, Gregory James Sylvester

    2009. “Evaluation of the Damage Detection Capability of alikelihood Estimation of Damage Location in Guided- waveStatistically-based Damage Detection in Geometrically-

  10. N-Terminal Enrichment: Developing a Protocol to Detect Specific...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Terminal Enrichment: Developing a Protocol to Detect Specific Proteolytic Fragments. N-Terminal Enrichment: Developing a Protocol to Detect Specific Proteolytic Fragments....

  11. Cyber Security Audit and Attack Detection Toolkit: Bandolier...

    Broader source: Energy.gov (indexed) [DOE]

    This project of the cyber security audit and attack detection toolkit will employ Bandolier Audit Files for optimizing security configurations and the Portaledge event detection...

  12. area damage detection: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    answer Cherkaev, Andrej 10 DAMAGE DETECTION IN STIFFENED AIRCRAFT PANELS VIA VIBRATION TESTING CiteSeer Summary: SUMMARY: The problem of damage detection in stiffened aircraft...

  13. Oxygen detected in atmosphere of Saturn's moon Dione

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Oxygen detected in atmosphere of Saturn's moon Dione Oxygen detected in atmosphere of Saturn's moon Dione Scientists and an international research team have announced discovery of...

  14. Detection of energetic particles and gamma rays Gas detectors

    E-Print Network [OSTI]

    Peletier, Reynier

    particles · electrons ­ neutral particles · neutrons · neutrinos · General radiation detection concepts radiation) ­ excitation (decay light can be the basis of radiation detection) ­ ionisation (electron

  15. An active system for the detection of special fissile material in small watercraft

    E-Print Network [OSTI]

    Johansen, Norman Alfan, III

    2006-10-30T23:59:59.000Z

    technique. The MCNP Monte Carlo transport code was used to simulate the use of a pulsed neutron generator to induce fission in the fissile material and then estimate the detector response. The detector modeled was based on elastic scattering-induced recoil...

  16. Passive Acoustic Detection of Wind Turbine In-Flow Conditions for Active Control and Optimization

    SciTech Connect (OSTI)

    Murray, Nathan E.

    2012-03-12T23:59:59.000Z

    Wind is a significant source of energy; however, the human capability to produce electrical energy still has many hurdles to overcome. One of these is the unpredictability of the winds in the atmospheric boundary layer (ABL). The ABL is highly turbulent in both stable and unstable conditions (based on the vertical temperature profile) and the resulting fluctuations can have a dramatic impact on wind turbine operation. Any method by which these fluctuations could be observed, estimated, or predicted could provide a benefit to the wind energy industry as a whole. Based on the fundamental coupling of velocity fluctuations to pressure fluctuations in the nearly incompressible flow in the ABL, This work hypothesizes that a ground-based array of infrasonic pressure transducers could be employed to estimate the vertical wind profile over a height relevant for wind turbines. To analyze this hypothesis, experiments and field deployments were conducted. Wind tunnel experiments were performed for a thick turbulent boundary layer over a neutral or heated surface. Surface pressure and velocity probe measurements were acquired simultaneously. Two field deployments yielded surface pressure data from a 49 element array. The second deployment at the Reese Technology Center in Lubbock, TX, also included data from a smaller aperture, 96-element array and a 200-meter tall meteorological tower. Analysis of the data successfully demonstrated the ability to estimate the vertical velocity profile using coherence data from the pressure array. Also, dynamical systems analysis methods were successful in identifying and tracking a gust type event. In addition to the passive acoustic profiling method, this program also investigated a rapid response Doppler SODAR system, the optimization of wind turbine blades for enhanced power with reduced aeroacoustic noise production, and the implementation of a wireless health monitoring system for the wind turbine blades. Each of these other objectives was met successfully. The use of phase unwrapping applied to SODAR data was found to yield reasonable results for per-pulse measurements. A health monitoring system design analysis was able to demonstrate the ability to use a very small number of sensors to monitor blade health based on the blade's overall structural modes. Most notable was the development of a multi-objective optimization methodology that successfully yielded an aerodynamic blade design that produces greater power output with reduced aerodynamic loading noise. This optimization method could be significant for future design work.

  17. Rapid detection of thrombin and other protease activity directly in whole blood

    E-Print Network [OSTI]

    Yu, Johnson Chung Sing

    2012-01-01T23:59:59.000Z

    and thrombin in sickle cell anemia. Thrombosis research10 . One known symptom of sickle cell anemia is coagulationin patients with sickle cell anemia 6 . As a result of

  18. Towards a sensor for detecting human presence and activity Y. Benezetha

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    is now one of those that consumes most energy. For example, in France, the building sector is responsible a background model updated at different levels to manage the most common variations of the environment focusing among other things on "Energy Management in Building", is then detailed. Three applications

  19. Adaptation of an enzyme-linked immunosorbent assay for detecting Brucella antibody activity in reindeer sera 

    E-Print Network [OSTI]

    Perry, Dana Lynn

    1982-01-01T23:59:59.000Z

    compared to conventional serologic results from the SPT, card, Rivanol, and CF methods. Sera were considered pos1tive by the SPT, Rivanol, and CF methods according to the criteria of a SPTA ' 50, SPTB '100, Rivanol '50, Hill's CF &40, and automated CF...lar manifestations 1n cattle (6), elk (7), and reindeer (8). Signs of infection 1n female animals include abortion, retained placentae, and birth of nonv1able offspring; signs in males include inflammation of the seminal vesicules, ampullae, test1...

  20. A Novel Technique for Improving Hardware Trojan Detection and Reducing Trojan Activation Time

    E-Print Network [OSTI]

    Plusquellic, James

    design and fabrication process has become a trend in Integrated Circuit (IC) market due to economical circuits have stealthy nature and are triggered in rare conditions. Trojans are designed,tehrani}@engr.uconn.edu Jim Plusquellic ECE Department University of New Mexico jimp@ece.unm.edu Abstract-- Fabless

  1. On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells

    E-Print Network [OSTI]

    Song, Qing

    The frequencies of antigen-specific CD4+ T cells in samples of human tissue have been difficult to determine accurately ex vivo, particularly for autoimmune diseases such as multiple sclerosis or type 1 diabetes. Conventional ...

  2. A system for distributed intrusion detection

    SciTech Connect (OSTI)

    Snapp, S.R.; Brentano, J.; Dias, G.V.; Goan, T.L.; Heberlein, L.T.; Ho, Che-Lin; Levitt, K.N.; Mukherjee, B. (California Univ., Davis, CA (USA). Div. of Computer Science); Grance, T. (Air Force Cryptologic Support Center, San Antonio, TX (USA)); Mansur, D.L.; Pon, K.L. (Lawrence Livermore National Lab., CA (USA)); Smaha, S.E. (Haystack Labs., Inc., Austin, TX (USA))

    1991-01-01T23:59:59.000Z

    The study of providing security in computer networks is a rapidly growing area of interest because the network is the medium over which most attacks or intrusions on computer systems are launched. One approach to solving this problem is the intrusion-detection concept, whose basic premise is that not only abandoning the existing and huge infrastructure of possibly-insecure computer and network systems is impossible, but also replacing them by totally-secure systems may not be feasible or cost effective. Previous work on intrusion-detection systems were performed on stand-alone hosts and on a broadcast local area network (LAN) environment. The focus of our present research is to extend our network intrusion-detection concept from the LAN environment to arbitarily wider areas with the network topology being arbitrary as well. The generalized distributed environment is heterogeneous, i.e., the network nodes can be hosts or servers from different vendors, or some of them could be LAN managers, like our previous work, a network security monitor (NSM), as well. The proposed architecture for this distributed intrusion-detection system consists of the following components: a host manager in each host; a LAN manager for monitoring each LAN in the system; and a central manager which is placed at a single secure location and which receives reports from various host and LAN managers to process these reports, correlate them, and detect intrusions. 11 refs., 2 figs.

  3. A Comparison Between Data Mining Prediction Algorithms for Fault Detection(Case study: Ahanpishegan co.)

    E-Print Network [OSTI]

    Amooee, Golriz; Bagheri-Dehnavi, Malihe

    2012-01-01T23:59:59.000Z

    In the current competitive world, industrial companies seek to manufacture products of higher quality which can be achieved by increasing reliability, maintainability and thus the availability of products. On the other hand, improvement in products lifecycle is necessary for achieving high reliability. Typically, maintenance activities are aimed to reduce failures of industrial machinery and minimize the consequences of such failures. So the industrial companies try to improve their efficiency by using different fault detection techniques. One strategy is to process and analyze previous generated data to predict future failures. The purpose of this paper is to detect wasted parts using different data mining algorithms and compare the accuracy of these algorithms. A combination of thermal and physical characteristics has been used and the algorithms were implemented on Ahanpishegan's current data to estimate the availability of its produced parts. Keywords: Data Mining, Fault Detection, Availability, Predictio...

  4. Performance Evaluation of DCA and SRC on a Single Bot Detection

    E-Print Network [OSTI]

    Al-Hammadi, Yousof; Greensmith, Julie

    2010-01-01T23:59:59.000Z

    Malicious users try to compromise systems using new techniques. One of the recent techniques used by the attacker is to perform complex distributed attacks such as denial of service and to obtain sensitive data such as password information. These compromised machines are said to be infected with malicious software termed a "bot". In this paper, we investigate the correlation of behavioural attributes such as keylogging and packet flooding behaviour to detect the existence of a single bot on a compromised machine by applying (1) Spearman's rank correlation (SRC) algorithm and (2) the Dendritic Cell Algorithm (DCA). We also compare the output results generated from these two methods to the detection of a single bot. The results show that the DCA has a better performance in detecting malicious activities.

  5. The Detection of Silicate Emission from Quasars at 10 and 18 Microns

    E-Print Network [OSTI]

    Lei Hao; H. W. W. Spoon; G. C. Sloan; J. A. Marshall; L. Armus; A. G. G. M. Tielens; B. Sargent; I. M. van Bemmel; V. Charmandaris; D. W. Weedman; J. R. Houck

    2005-04-19T23:59:59.000Z

    We report the spectroscopic detection of silicate emission at 10 and 18 microns in five PG quasars, the first detection of these two features in galaxies outside the Local Group. This finding is consistent with the unification model for Active Galactic Nuclei (AGNs), which predicts that an AGN torus seen pole-on should show a silicate emission feature in the mid-infrared. The strengths of the detected silicate emission features range from 0.12 to 1.25 times the continuum at 10 microns and from 0.20 to 0.79 times the continuum at 18 microns. The silicate grain temperatures inferred from the ratio of 18-to-10 micron silicate features under the assumption of optically thin emission range from 140 to 220K.

  6. Low energy conversion electron detection in superfluid He3 at ultra-low temperature

    E-Print Network [OSTI]

    E. Moulin; C. Winkelmann; J. F. Macias-Perez; Yu. M. Bunkov; H. Godfrin; D. Santos

    2005-04-12T23:59:59.000Z

    We report on the first results of the MACHe3 (MAtrix of Cells of Helium 3) prototype experiment concerning the measurement of low energy conversion electrons at ultra-low temperature. For the first time, the feasibility of the detection of low energy electrons is demonstrated in superfluid He3-B cooled down to 100 microK. Low energy electrons at 7.3 keV coming from the K shell conversion of the 14.4 keV nuclear transition of a low activity Co57 source are detected, opening the possibility to use a He3-based detector for the detection of Weakly Interacting Massive Particles (WIMPs) which are expected to release an amount of energy higher-bounded by 5.6 keV.

  7. Design and evaluation of the ReKon : an integrated detection and assessment perimeter system.

    SciTech Connect (OSTI)

    Dabling, Jeffrey Glenn; Andersen, Jason Jann; McLaughlin, James O. [Stonewater Control Systems, Inc., Kannapolis, NC

    2013-02-01T23:59:59.000Z

    Kontek Industries (Kannapolis, NC) and their subsidiary, Stonewater Control Systems (Kannapolis, NC), have entered into a cooperative research and development agreement with Sandia to jointly develop and evaluate an integrated perimeter security system solution, one that couples access delay with detection and assessment. This novel perimeter solution was designed to be configurable for use at facilities ranging from high-security military sites to commercial power plants, to petro/chemical facilities of various kinds. A prototype section of the perimeter has been produced and installed at the Sandia Test and Evaluation Center in Albuquerque, NM. This prototype system integrated fiber optic break sensors, active infrared sensors, fence disturbance sensors, video motion detection, and ground sensors. This report documents the design, testing, and performance evaluation of the developed ReKon system. The ability of the system to properly detect pedestrian or vehicle attempts to bypass, breach, or otherwise defeat the system is characterized, as well as the Nuisance Alarm Rate.

  8. Active System For Monitoring Volcanic Activity- A Case Study...

    Open Energy Info (EERE)

    Central Japan Jump to: navigation, search OpenEI Reference LibraryAdd to library Journal Article: Active System For Monitoring Volcanic Activity- A Case Study Of The...

  9. System and method for detecting cells or components thereof

    DOE Patents [OSTI]

    Porter, Marc D. (Ames, IA); Lipert, Robert J. (Ames, IA); Doyle, Robert T. (Ames, IA); Grubisha, Desiree S. (Corona, CA); Rahman, Salma (Ames, IA)

    2009-01-06T23:59:59.000Z

    A system and method for detecting a detectably labeled cell or component thereof in a sample comprising one or more cells or components thereof, at least one cell or component thereof of which is detectably labeled with at least two detectable labels. In one embodiment, the method comprises: (i) introducing the sample into one or more flow cells of a flow cytometer, (ii) irradiating the sample with one or more light sources that are absorbed by the at least two detectable labels, the absorption of which is to be detected, and (iii) detecting simultaneously the absorption of light by the at least two detectable labels on the detectably labeled cell or component thereof with an array of photomultiplier tubes, which are operably linked to two or more filters that selectively transmit detectable emissions from the at least two detectable labels.

  10. Measuring indigenous photosynthetic organisms to detect chemical warefare agents in water

    DOE Patents [OSTI]

    Greenbaum, Elias; Sanders, Charlene A.

    2005-11-15T23:59:59.000Z

    A method of testing water to detect the presence of a chemical or biological warfare agent is disclosed. The method is carried out by establishing control data by providing control water containing indigenous organisms but substantially free of a chemical and a biological warfare agent. Then measuring photosynthetic activity of the control water with a fluorometer to obtain control data to compare with test data to detect the presence of the chemical or agent. The test data is gathered by providing test water comprising the same indigenous organisms as contained in the control water. Further, the test water is suspected of containing the chemical or agent to be tested for. Photosynthetic activity is also measured by fluorescence induction in the test water using a fluorometer.

  11. Crack detection diagnostics using ultrasonic insonification

    E-Print Network [OSTI]

    Jarmer, Gregory James Sylvester

    2009-01-01T23:59:59.000Z

    xiii Chapter 1 Structural Health Monitoring . . . . 1.1Active Sensors for Structural Health Monitoring. Journal ofC.R. Farrar. Structural health monitoring using statistical

  12. Probe for contamination detection in recyclable materials

    DOE Patents [OSTI]

    Taleyarkhan, Rusi

    2003-08-05T23:59:59.000Z

    A neutron detection system for detection of contaminants contained within a bulk material during recycling includes at least one neutron generator for neutron bombardment of the bulk material, and at least one gamma ray detector for detection of gamma rays emitted by contaminants within the bulk material. A structure for analyzing gamma ray data is communicably connected to the gamma ray detector, the structure for analyzing gamma ray data adapted. The identity and concentration of contaminants in a bulk material can also be determined. By scanning the neutron beam, discrete locations within the bulk material having contaminants can be identified. A method for recycling bulk material having unknown levels of contaminants includes the steps of providing at least one neutron generator, at least one gamma ray detector, and structure for analyzing gamma ray data, irradiating the bulk material with neutrons, and then determining the presence of at least one contaminant in the bulk material from gamma rays emitted from the bulk material.

  13. Tissue-based water quality biosensors for detecting chemical warfare agents

    DOE Patents [OSTI]

    Greenbaum, Elias (Oak Ridge, TN); Sanders, Charlene A. (Knoxville, TN)

    2003-05-27T23:59:59.000Z

    A water quality sensor for detecting the presence of at least one chemical or biological warfare agent includes: a cell; apparatus for introducing water into the cell and discharging water from the cell adapted for analyzing photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms in water; a fluorometer for measuring photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms drawn into the cell; and an electronics package that analyzes raw data from the fluorometer and emits a signal indicating the presence of at least one chemical or biological warfare agent in the water.

  14. Apparatus and methods for real-time detection of explosives devices

    DOE Patents [OSTI]

    Blackburn, Brandon W [Idaho Falls, ID; Hunt, Alan W [Pocatello, ID; Chichester, David L [Idaho Falls, ID

    2014-01-07T23:59:59.000Z

    The present disclosure relates, according to some embodiments, to apparatus, devices, systems, and/or methods for real-time detection of a concealed or camouflaged explosive device (e.g., EFPs and IEDs) from a safe stand-off distance. Apparatus, system and/or methods of the disclosure may also be operable to identify and/or spatially locate and/or detect an explosive device. An apparatus or system may comprise an x-ray generator that generates high-energy x-rays and/or electrons operable to contact and activate a metal comprised in an explosive device from a stand-off distance; and a detector operable to detect activation of the metal. Identifying an explosive device may comprise detecting characteristic radiation signatures emitted by metals specific to an EFP, an IED or a landmine. Apparatus and systems of the disclosure may be mounted on vehicles and methods of the disclosure may be performed while moving in the vehicle and from a safe stand-off distance.

  15. Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway

    SciTech Connect (OSTI)

    Li, Yanyan; Gao, Chao; Shi, Yanru; Tang, Yuhan; Liu, Liang; Xiong, Ting; Du, Min [Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Ministry of Education Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Xing, Mingyou [Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Liu, Liegang [Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Ministry of Education Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Yao, Ping, E-mail: yaoping@mails.tjmu.edu.cn [Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Ministry of Education Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China); Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030 (China)

    2013-11-15T23:59:59.000Z

    Stress-inducible protein heme oxygenase-1(HO-1) is well-appreciative to counteract oxidative damage and inflammatory stress involving the pathogenesis of alcoholic liver diseases (ALD). The potential role and signaling pathways of HO-1 metabolite carbon monoxide (CO), however, still remained unclear. To explore the precise mechanisms, ethanol-dosed adult male Balb/c mice (5.0 g/kg.bw.) or ethanol-incubated primary rat hepatocytes (100 mmol/L) were pretreated by tricarbonyldichlororuthenium (II) dimmer (CORM-2, 8 mg/kg for mice or 20 ?mol/L for hepatocytes), as well as other pharmacological reagents. Our data showed that CO released from HO-1 induction by quercetin prevented ethanol-derived oxidative injury, which was abolished by CO scavenger hemoglobin. The protection was mimicked by CORM-2 with the attenuation of GSH depletion, SOD inactivation, MDA overproduction, and the leakage of AST, ALT or LDH in serum and culture medium induced by ethanol. Moreover, CORM-2 injection or incubation stimulated p38 phosphorylation and suppressed abnormal Tnfa and IL-6, accompanying the alleviation of redox imbalance induced by ethanol and aggravated by inflammatory factors. The protective role of CORM-2 was abolished by SB203580 (p38 inhibitor) but not by PD98059 (ERK inhibitor) or SP600125 (JNK inhibitor). Thus, HO-1 released CO prevented ethanol-elicited hepatic oxidative damage and inflammatory stress through activating p38 MAPK pathway, suggesting a potential therapeutic role of gaseous signal molecule on ALD induced by naturally occurring phytochemicals. - Highlights: • CO alleviated ethanol-derived liver oxidative and inflammatory stress in mice. • CO eased ethanol and inflammatory factor-induced oxidative damage in hepatocytes. • The p38 MAPK is a key signaling mechanism for the protective function of CO in ALD.

  16. System for particle concentration and detection

    DOE Patents [OSTI]

    Morales, Alfredo M.; Whaley, Josh A.; Zimmerman, Mark D.; Renzi, Ronald F.; Tran, Huu M.; Maurer, Scott M.; Munslow, William D.

    2013-03-19T23:59:59.000Z

    A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip.

  17. Advanced technologies for perimeter intrusion detection sensors

    SciTech Connect (OSTI)

    Williams, J.D.

    1995-03-01T23:59:59.000Z

    The development of integrated circuit fabrication techniques and the resulting devices have contributed more to the advancement of exterior intrusion detectors and alarm assessment devices than any other technology. The availability of this technology has led to the improvements in and further development of smaller more powerful computers, microprocessors, solid state memories, solid state cameras, thermal imagers, low-power lasers, and shorter pulse width and higher frequency electronic circuitry. This paper presents information on planning a perimeter intrusion detection system, identifies the site characteristics that affect its performance, and describes improvements to perimeter intrusion detection sensors and assessment devices that have been achieved by using integrated circuit technology.

  18. Nauru Island Effect Detection Data Set

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Long, Chuck

    During Nauru99 it was noted that the island was producing small clouds that advected over the ARM site. The Nauru Island Effect Study was run for 1.5 years and the methodology developed to detect the occurrence. Nauru ACRF downwelling SW, wind direction, and air temperature data are used, along with downwelling SW data from Licor radiometers located on the southern end of the island near the airport landing strip. A statistical analysis and comparison of data from the two locations is used to detect the likely occurrence of an island influence on the Nauru ACRF site data

  19. System For Detection Of Hazardous Events

    DOE Patents [OSTI]

    Kulesz, James J [Oak Ridge, TN; Worley, Brian A [Knoxville, TN

    2005-08-16T23:59:59.000Z

    A system for detecting the occurrence of anomalies, includes a plurality of spaced apart nodes, with each node having adjacent nodes, each of the nodes having one or more sensors associated with the node and capable of detecting anomalies, and each of the nodes having a controller connected to the sensors associated with the node. The system also includes communication links between adjacent nodes, whereby the nodes form a network. Each controller is programmed to query its adjacent nodes to assess the status of the adjacent nodes and the communication links.

  20. System for detection of hazardous events

    DOE Patents [OSTI]

    Kulesz, James J.; Worley, Brian A.

    2006-05-23T23:59:59.000Z

    A system for detecting the occurrence of anomalies, includes a plurality of spaced apart nodes, with each node having adjacent nodes, each of the nodes having one or more sensors associated with the node and capable of detecting anomalies, and each of the nodes having a controller connected to the sensors associated with the node. The system also includes communication links between adjacent nodes, whereby the nodes form a network. Each controller is programmed to query its adjacent nodes to assess the status of the adjacent nodes and the communication links.