National Library of Energy BETA

Sample records for detectable activity mda

  1. Energy Detectives (3 Activities)

    K-12 Energy Lesson Plans and Activities Web site (EERE)

    Students explore the classroom as they look and feel for signs of energy. They record the ways they use energy throughout a typical day in an energy detective journal.

  2. Analyte detection using an active assay

    DOE Patents [OSTI]

    Morozov, Victor (Manassas, VA); Bailey, Charles L. (Cross Junction, VA); Evanskey, Melissa R. (Potomac Falls, VA)

    2010-11-02

    Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membrane may be semi-permeable to nonanalytes. The layer of polymers may include cross-linked polymers. A plurality of probe molecules may be arrayed and immobilized on the lacquered membrane. An external force may be applied to the analyte solution to move the analytes towards the lacquered membrane. Movement may cause some or all of the analytes to bind to the lacquered membrane. In cases where probe molecules are presented, some or all of the analytes may bind to probe molecules. The direction of the external force may be reversed to remove unbound or weakly bound analytes. Bound analytes may be detected using known detection types.

  3. Rapid dimerization of quercetin through an oxidative mechanism in the presence of serum albumin decreases its ability to induce cytotoxicity in MDA-MB-231 cells

    SciTech Connect (OSTI)

    Pham, Anh; Bortolazzo, Anthony [Department of Biological Sciences, San Jose State University, San Jose, CA 95192-0100 (United States)] [Department of Biological Sciences, San Jose State University, San Jose, CA 95192-0100 (United States); White, J. Brandon, E-mail: Brandon.White@sjsu.edu [Department of Biological Sciences, San Jose State University, San Jose, CA 95192-0100 (United States)

    2012-10-19

    Highlights: Black-Right-Pointing-Pointer Quercetin cannot be detected intracellularly despite killing MDA-MB-231 cells. Black-Right-Pointing-Pointer Quercetin forms a heterodimer through oxidation in media with serum. Black-Right-Pointing-Pointer The quercetin heterodimer does not kill MDA-MB-231 cells. Black-Right-Pointing-Pointer Ascorbic acid stabilizes quercetin increasing cell death in quercetin treated cells. Black-Right-Pointing-Pointer Quercetin, and not a modified form, is responsible for apoptosis and cell death. -- Abstract: Quercetin is a member of the flavonoid family and has been previously shown to have a variety of anti-cancer activities. We and others have reported anti-proliferation, cell cycle arrest, and induction of apoptosis of cancer cells after treatment with quercetin. Quercetin has also been shown to undergo oxidation. However, it is unclear if quercetin or one of its oxidized forms is responsible for cell death. Here we report that quercetin rapidly oxidized in cell culture media to form a dimer. The quercetin dimer is identical to a dimer that is naturally produced by onions. The quercetin dimer and quercetin-3-O-glucopyranoside are unable to cross the cell membrane and do not kill MDA-MB-231 cells. Finally, supplementing the media with ascorbic acid increases quercetin's ability to induce cell death probably by reduction oxidative dimerization. Our results suggest that an unmodified quercetin is the compound that elicits cell death.

  4. Detecting Termination of Active Database Rules Using Symbolic Model Checking

    E-Print Network [OSTI]

    Ray, Indrakshi

    Detecting Termination of Active Database Rules Using Symbolic Model Checking Indrakshi Ray is the non-termination of rules. Although algorithms have been proposed to detect non-termination, al- most all provide a conservative estimate; that is, the algorithms detect all the potential cases of non-termination

  5. An active oil spill detection digital processing system 

    E-Print Network [OSTI]

    Dennard, Robert Marion

    1976-01-01

    AN ACTIVE OIL SPILL DETECTION DIGITAL PROCESSING SYSTEM A Thesis by Robert Marion Dennard Submitted to the Graduate College of Texas A/M University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE December 1976... Major Subject: Electrical Engineering AN ACTIVE OIL SPILL DETECTION DIGITAL PROCESSING SYSTEM A Thesis by Robert Marion Dennard Approved as to style and content by: Chairman o Committee Hea o epart ent M er em er December 1976 ABSTRACT...

  6. 2011-07 "Maximum Utilization of WIPP by Increasing MDA G TRU...

    Office of Environmental Management (EM)

    7 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" 2011-07 "Maximum Utilization of WIPP by Increasing MDA G TRU Shipments" The intent of this recommendation is to...

  7. Electrochemical Proteolytic Beacon for Detection of Matrix Metalloproteinase Activities

    SciTech Connect (OSTI)

    Liu, Guodong; Wang, Jun; Wunschel, David S.; Lin, Yuehe

    2006-09-27

    This communication describes a novel method for detecting of matrix metalloproteinase-7 activity using a peptide substrate labeled with a ferrocene reporter. The substrate serves as a selective ‘electrochemical proteolytic beacon’ (EPB) for this metalloproteinase. The EPB is immobilized on a gold electrode surface to enable ‘on-off’ electrochemical signaling capability for uncleaved and cleaved events. The EPB is efficiently and selectively cleaved by MMP-7 as measured by the rate of decrease in redox current of ferrocene. Direct transduction of a signal corresponding to peptide cleavage events into an electronic signal thus provides a simple, sensitive route for detecting the MMP activity. The new method allows for identification of the activity of MMP-7 in concentrations as low as 3.4 pM. The concept can be extended to design multiple peptide substrate labeled with different electroactive reporters for assaying multiple MMPs activities.

  8. Regulation of MDA-MB-231 cell proliferation by GSK-3? involves epigenetic modifications under high glucose conditions

    SciTech Connect (OSTI)

    Gupta, Chanchal; Kaur, Jasmine; Tikoo, Kulbhushan

    2014-05-15

    Hyperglycemia is a critical risk factor for development and progression of breast cancer. We have recently reported that high glucose induces phosphorylation of histone H3 at Ser 10 as well as de-phosphorylation of GSK-3? at Ser 9 in MDA-MB-231 cells. Here, we elucidate the mechanism underlying hyperglycemia-induced proliferation in MDA-MB-231 breast cancer cells. We provide evidence that hyperglycemia led to increased DNA methylation and DNMT1 expression in MDA-MB-231 cells. High glucose condition led to significant increase in the expression of PCNA, cyclin D1 and decrease in the expression of PTPN 12, p21 and PTEN. It also induced hypermethylation of DNA at the promoter region of PTPN 12, whereas hypomethylation at Vimentin and Snail. Silencing of GSK-3? by siRNA prevented histone H3 phosphorylation and reduced DNMT1 expression. We show that chromatin obtained after immunoprecipitation with phospho-histone H3 was hypermethylated under high glucose condition, which indicates a cross-talk between DNA methylation and histone H3 phosphorylation. ChIP-qPCR analysis revealed up-regulation of DNMT1 and metastatic genes viz. Vimentin, Snail and MMP-7 by phospho-histone H3, which were down-regulated upon GSK-3? silencing. To the best of our knowledge, this is the first report which shows that interplay between GSK-3? activation, histone H3 phosphorylation and DNA methylation directs proliferation of breast cancer cells. - Highlights: • High glucose induces phosphorylation of histone H3 and dephosphorylation of GSK-3?. • Moreover, hyperglycemia also leads to increased DNA methylation in MDA-MB-231 cells. • Inhibition of GSK-3? prevented histone H3 phosphorylation and reduced DNMT1 levels. • Interplay exists between GSK-3?, histone H3 phosphorylation and DNA methylation.

  9. SOLAR ACTIVITY DETECTION AND PREDICTION USING IMAGE PROCESSING AND MACHINE LEARNING TECHNIQUES

    E-Print Network [OSTI]

    ABSTRACT SOLAR ACTIVITY DETECTION AND PREDICTION USING IMAGE PROCESSING AND MACHINE LEARNING for automatic detection and prediction of solar activities, including prominence eruptions, emerging flux. These methods can be used for automatic observation of solar activities and prediction of space weather that may

  10. Active salt tectonics in the Needles District, Canyonlands (Utah) as detected by interferometric

    E-Print Network [OSTI]

    Mueller, Karl

    Active salt tectonics in the Needles District, Canyonlands (Utah) as detected by interferometric. Mueller, and J. Wahr (2007), Active salt tectonics in the Needles District, Canyonlands (Utah) as detected, overlying a mobile layer of evaporites (the Paradox Formation) that originated mostly as salt deposited

  11. Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces

    DOE Patents [OSTI]

    Salafsky, Joshua S.; Eisenthal, Kenneth B.

    2005-10-11

    This invention provides methods of detecting molecules at an interface, which comprise labeling the molecules with a second harmonic-active moiety and detecting the labeled molecules at the interface using a surface selective technique. The invention also provides methods for detecting a molecule in a medium and for determining the orientation of a molecular species within a planar surface using a second harmonic-active moiety and a surface selective technique.

  12. Analyzing and Detecting Malicious Activities in Emerging Communication Platforms 

    E-Print Network [OSTI]

    Yang, Chao

    2014-06-05

    and smartphone platforms, and to develop effective and efficient defense approaches against those malicious activities. Firstly, this dissertation performs an empirical analysis of the cyber criminal ecosystem on a large-scale online social networking website...

  13. detection

    National Nuclear Security Administration (NNSA)

    of 25 Million Grant to Improve Technological Capabilities for Detecting Nuclear Proliferation http:www.nnsa.energy.govmediaroompressreleasesncstateconsortium

  14. Methods for improved selectivity in photo-activation and detection of molecular diagnostic agents

    DOE Patents [OSTI]

    Wachter, Eric A. (Oak Ridge, TN); Fisher, Walter G. (Knoxville, TN); Dees, H. Craig (Knoxville, TN)

    2008-03-18

    A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method comprises the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photo-activating at least one of the at least one photo-active molecular agent in the particular volume of the plant or animal tissue, thereby producing at least one photo-activated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photo-activated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue. The present invention also provides a method for the imaging of a particular volume of material, wherein the material contains at least one photo-active molecular agent.

  15. Method for improved selectivity in photo-activation and detection of molecular diagnostic agents

    DOE Patents [OSTI]

    Wachter, Eric A. (Oak Ridge, TN); Fisher, Walter G. (Knoxville, TN); Dees, H. Craig (Knoxville, TN)

    1998-01-01

    A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method includes the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photo-activating at least one of the at least one photo-active molecular agent in the particular volume of the plant or animal tissue, thereby producing at least one photo-activated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photo-activated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue. The present invention is also a method for the imaging of a particular volume of material, wherein the material contains at least one photo-active molecular agent.

  16. Method for improved selectivity in photo-activation and detection of molecular diagnostic agents

    DOE Patents [OSTI]

    Wachter, E.A.; Fisher, W.G.; Dees, H.C.

    1998-11-10

    A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method includes the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photo-activating at least one of the at least one photo-active molecular agent in the particular volume of the plant or animal tissue, thereby producing at least one photo-activated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photo-activated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue. The present invention is also a method for the imaging of a particular volume of material, wherein the material contains at least one photo-active molecular agent. 13 figs.

  17. Modeling of activation data in the BrainMap TM database: Detection of outliers

    E-Print Network [OSTI]

    Nielsen, Finn Ã?rup

    Modeling of activation data in the BrainMap TM database: Detection of outliers Finn š Arup Nielsen­Analysis, Data Analysis, Estimation Techniques, Probabilistic Models, Neuroanatomy, Databases, Neural Networks and Lars Kai Hansen Informatics and Mathematical Modelling Technical University of Denmark DK­2800 Lyngby

  18. Tuned Lamb Wave Excitation and Detection with Piezoelectric Wafer Active Sensors for Structural Health Monitoring

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    and detect tuned Lamb waves for structural health monitoring is explored. First, a brief review of Lamb waves mode Lamb waves is demonstrated as an effective structural health monitoring method. Key Words: structural health monitoring, Lamb waves, piezoelectric wafer active sensors, aging aircraft, cracks, damage

  19. Energy-Efficient Multihypothesis Activity-Detection for Health-Monitoring Applications

    E-Print Network [OSTI]

    Annavaram, Murali

    in a star topology, which send samples to a cell phone fusion center via Bluetooth that employs a "serve-Metz Abstract-- Multi-hypothesis activity-detection using a wire- less body area network is considered. A fusion as available" protocol. In this protocol, all samples taken by each sensor are collected by the fusion center

  20. Photo-activated luminescence sensor and method of detecting trichloroethylene and related volatile organochloride compounds

    DOE Patents [OSTI]

    Dinh, T.V.

    1996-06-11

    A sensor for detecting trichloroethylene and related volatile organochloride compounds uses a photo-activator that produces a photo-product complex with the contaminant. Characteristics of the light emitted from the complex will indicate the presence of the contaminant. A probe containing the photo-activator has an excitation light interface and a contaminant interface. One particular embodiment uses a porous membrane as the contaminant interface, so that the contaminant can migrate there through to the photo-activator and thereby form the complex. 23 figs.

  1. Photo-activated luminescence sensor and method of detecting trichloroethylene and related volatile organochloride compounds

    DOE Patents [OSTI]

    Dinh, Tuan V. (Knoxville, TN)

    1996-01-01

    A sensor for detecting trichloroethylene and related volatile organochloride compounds uses a photo-activator that produces a photo-product complex with the contaminant. Characteristics of the light emitted from the complex will indicate the presence of the contaminant. A probe containing the photo-activator has an excitation light interface and a contaminant interface. One particular embodiment uses a porous membrane as the contaminant interface, so that the contaminant can migrate therethrough to the photo-activator and thereby form the complex.

  2. Methods, microfluidic devices, and systems for detection of an active enzymatic agent

    DOE Patents [OSTI]

    Sommer, Gregory J; Hatch, Anson V; Singh, Anup K; Wang, Ying-Chih

    2014-10-28

    Embodiments of the present invention provide methods, microfluidic devices, and systems for the detection of an active target agent in a fluid sample. A substrate molecule is used that contains a sequence which may cleave in the presence of an active target agent. A SNAP25 sequence is described, for example, that may be cleaved in the presence of Botulinum Neurotoxin. The substrate molecule includes a reporter moiety. The substrate molecule is exposed to the sample, and resulting reaction products separated using electrophoretic separation. The elution time of the reporter moiety may be utilized to identify the presence or absence of the active target agent.

  3. Stellar activity as noise in exoplanet detection I. Methods and application to solar-like stars and activity cycles

    E-Print Network [OSTI]

    Korhonen, H; Piskunov, N; Hackman, T; Juncher, D; Jarvinen, S P; Joergensen, U G

    2015-01-01

    The detection of exoplanets using any method is prone to confusion due to the intrinsic variability of the host star. We investigate the effect of cool starspots on the detectability of the exoplanets around solar-like stars using the radial velocity method. For investigating this activity-caused "jitter" we calculate synthetic spectra using radiative transfer, known stellar atomic and molecular lines, different surface spot configurations, and an added planetary signal. Here, the methods are described in detail, tested and compared to previously published studies. The methods are also applied to investigate the activity jitter in old and young solar-like stars, and over a solar-like activity cycles. We find that the mean full jitter amplitude obtained from the spot surfaces mimicking the solar activity varies during the cycle approximately between 1 m/s and 9 m/s. With a realistic observing frequency a Neptune mass planet on a one year orbit can be reliably recovered. On the other hand, the recovery of an Ea...

  4. Detecting Internet Outages with Precise Active Probing USC/ISI Technical Report ISI-TR-678b

    E-Print Network [OSTI]

    Heidemann, John

    Detecting Internet Outages with Precise Active Probing (extended) USC/ISI Technical Report ISI Japanese earthquake, to the thousands of small outages caused by localized accidents, and human error, motivating our new system to detect network outages by active probing. We show that a single computer can

  5. Estimation of the Performance of Multiple Active Neutron Interrogation Signatures for Detecting Shielded HEU

    SciTech Connect (OSTI)

    David L. Chichester; Scott J. Thompson; Scott M. Watson; James T. Johnson; Edward H. Seabury

    2012-10-01

    A comprehensive modeling study has been carried out to evaluate the utility of multiple active neutron interrogation signatures for detecting shielded highly enriched uranium (HEU). The modeling effort focused on varying HEU masses from 1 kg to 20 kg; varying types of shields including wood, steel, cement, polyethylene, and borated polyethylene; varying depths of the HEU in the shields, and varying engineered shields immediately surrounding the HEU including steel, tungsten, and cadmium. Neutron and gamma-ray signatures were the focus of the study and false negative detection probabilities versus measurement time were used as a performance metric. To facilitate comparisons among different approaches an automated method was developed to generate receiver operating characteristic (ROC) curves for different sets of model variables for multiple background count rate conditions. This paper summarizes results or the analysis, including laboratory benchmark comparisons between simulations and experiments. The important impact engineered shields can play towards degrading detectability and methods for mitigating this will be discussed.

  6. Chemical hazard evaluation of material disposal area (MDA) B closure project

    SciTech Connect (OSTI)

    Laul, Jagdish C

    2010-04-19

    TA-21, MDA-B (NES) is the 'contaminated dump,' landfill with radionuclides and chemicals from process waste disposed in 1940s. This paper focuses on chemical hazard categorization and hazard evaluation of chemicals of concern (e.g., peroxide, beryllium). About 170 chemicals were disposed in the landfill. Chemicals included products, unused and residual chemicals, spent, waste chemicals, non-flammable oils, mineral oil, etc. MDA-B was considered a High hazard site. However, based on historical records and best engineering judgment, the chemical contents are probably at best 5% of the chemical inventory. Many chemicals probably have oxidized, degraded or evaporated for volatile elements due to some fire and limited shelf-life over 60 yrs, which made it possible to downgrade from High to Low chemical hazard site. Knowing the site history and physical and chemical properties are very important in characterizing a NES site. Public site boundary is only 20 m, which is a major concern. Chemicals of concern during remediation are peroxide that can cause potential explosion and beryllium exposure due to chronic beryllium disease (CBD). These can be prevented or mitigated using engineering control (EC) and safety management program (SMP) to protect the involved workers and public.

  7. Optically Detected Magnetic Resonance and Thermal Activation Spectroscopy Study of Organic Semiconductors

    SciTech Connect (OSTI)

    Chang-Hwan Kim

    2003-12-12

    Organic electronic materials are a new class of emerging materials. Organic light emitting devices (OLEDs) are the most promising candidates for future flat panel display technologies. The photophysical characterization is the basic research step one must follow to understand this new class of materials and devices. The light emission properties are closely related to the transport properties of these materials. The objective of this dissertation is to probe the relation between transport and photophysical properties of organic semiconductors. The transport characteristics were evaluated by using thermally stimulated current and thermally stimulated luminescence techniques. The photoluminescence detected magnetic resonance and photoluminescence quantum yield studies provide valuable photophysical information on this class of materials. OLEDs are already in the market. However, detailed studies on the degradation mechanisms are still lacking. Since both optically detected magnetic resonance and thermal activation spectroscopy probe long-lived defect-related states in organic semiconductors, the combined study generates new insight on the OLED operation and degradation mechanisms.

  8. The Third Catalog of Active Galactic Nuclei Detected by the Fermi Large Area Telescope

    E-Print Network [OSTI]

    Ackermann, M; Atwood, W; Baldini, L; Ballet, J; Barbiellini, G; Bastieri, D; Gonzalez, J; Bellazzini, R; Bissaldi, E; Blandford, R; Bloom, E; Bonino, R; Bottacini, E; Brandt, T; Bregeon, J; Britto, R; Bruel, P; Buehler, R; Buson, S; Caliandro, G; Cameron, R; Caragiulo, M; Caraveo, P; Casandjian, J; Cavazzuti, E; Cecchi, C; Charles, E; Chekhtman, A; Cheung, C; Chiang, J; Chiaro, G; Ciprini, S; Claus, R; Cohen-Tanugi, J; Cominsky, L; Conrad, J; Cutini, S; D'Abrusco, R; D'Ammando, F; Angelis, A; Desiante, R; Digel, S; Venere, L; Drell, P; Favuzzi, C; Fegan, S; Ferrara, E; Finke, J; Focke, W; Franckowiak, A; Fuhrmann, L; Furniss, A; Fusco, P; Gargano, F; Gasparrini, D; Giglietto, N; Giommi, P; Giordano, F; Giroletti, M; Glanzman, T; Godfrey, G; Grenier, I; Grove, J; Guiriec, S; Hewitt, J W; Hill, A; Horan, D; J'ohannesson, G; Johnson, A; Johnson, W; Kataoka, J; Kuss, M; Mura, G; Larsson, S; Latronico, L; Leto, C; Li, J; Li, L; Longo, F; Loparco, F; Lott, B; Lovellette, M; Lubrano, P; Madejski, G; Mayer, M; Mazziotta, M; McEnery, J; Michelson, P; Mizuno, T; Moiseev, A; Monzani, M; Morselli, A; Moskalenko, I; Murgia, S; Nuss, E; Ohno, M; Ohsugi, T; Ojha, R; Omodei, N; Orienti, M; Orlando, E; Paggi, A; Paneque, D; Perkins, J; Pesce-Rollins, M; Piron, F; Pivato, G; Porter, T; Rain`o, S; Rando, R; Razzano, M; Razzaque, S; Reimer, A; Reimer, O; Romani, R; Salvetti, D; Schaal, M; Schinzel, F; Schulz, A; Sgr`o, C; Siskind, E; Sokolovsky, K; Spada, F; Spandre, G; Spinelli, P; Stawarz, L; Suson, D; Takahashi, H; Takahashi, T; Tanaka, Y; Thayer, J; Tibaldo, L; Torres, D; Torresi, E; Tosti, G; Troja, E; Uchiyama, Y; Vianello, G; Winer, B; Wood, K; Zimmer, S

    2015-01-01

    The third catalog of active galactic nuclei (AGNs) detected by the Fermi-LAT (3LAC) is presented. It is based on the third Fermi-LAT catalog (3FGL) of sources detected with a test statistic (TS) greater than 25, using the first 4 years of data. The 3LAC includes 1591 AGNs located at high Galactic latitudes (|b|>10{\\deg}), which is a 71% increase over the second catalog that was based on 2 years of data. There are 28 duplicate associations (two counterparts to the same gamma-ray source), thus 1563 of the 2192 high-latitude gamma-ray sources of the 3FGL catalog are AGNs. A very large majority of these AGNs (98%) are blazars. About half of the newly detected blazars are of unknown type, i.e., they lack spectroscopic information of sufficient quality to determine the strength of their emission lines. Based on their spectral properties, these sources are evenly split between FSRQs and BL~Lacs. The general properties of the 3LAC sample confirm previous findings from earlier catalogs, but some new subclasses (e.g., ...

  9. Rear-Facing Car Safety Seats: Getting the Message Marilyn J. Bull, MDa, Dennis R. Durbin, MD, MSCEb

    E-Print Network [OSTI]

    COMMENTARY Rear-Facing Car Safety Seats: Getting the Message Right Marilyn J. Bull, MDa, Dennis R and young children regarding the safest way for them to ride in a car. Child fatalities and injuries and research provided by the National High- way Traffic Safety Administration, the car safety seat

  10. DETECTING ACTIVE GALACTIC NUCLEI USING MULTI-FILTER IMAGING DATA. II. INCORPORATING ARTIFICIAL NEURAL NETWORKS

    SciTech Connect (OSTI)

    Dong, X. Y.; De Robertis, M. M., E-mail: xydong@yorku.ca [Physics and Astronomy Department, York University, Toronto, ON M3J 1P3 (Canada)

    2013-10-01

    This is the second paper of the series Detecting Active Galactic Nuclei Using Multi-filter Imaging Data. In this paper we review shapelets, an image manipulation algorithm, which we employ to adjust the point-spread function (PSF) of galaxy images. This technique is used to ensure the image in each filter has the same and sharpest PSF, which is the preferred condition for detecting AGNs using multi-filter imaging data as we demonstrated in Paper I of this series. We apply shapelets on Canada-France-Hawaii Telescope Legacy Survey Wide Survey ugriz images. Photometric parameters such as effective radii, integrated fluxes within certain radii, and color gradients are measured on the shapelets-reconstructed images. These parameters are used by artificial neural networks (ANNs) which yield: photometric redshift with an rms of 0.026 and a regression R-value of 0.92; galaxy morphological types with an uncertainty less than 2 T types for z ? 0.1; and identification of galaxies as AGNs with 70% confidence, star-forming/starburst (SF/SB) galaxies with 90% confidence, and passive galaxies with 70% confidence for z ? 0.1. The incorporation of ANNs provides a more reliable technique for identifying AGN or SF/SB candidates, which could be very useful for large-scale multi-filter optical surveys that also include a modest set of spectroscopic data sufficient to train neural networks.

  11. Photon-axion mixing within the jets of active galactic nuclei and prospects for detection

    SciTech Connect (OSTI)

    Harris, J.; Chadwick, P.M. E-mail: p.m.chadwick@durham.ac.uk

    2014-10-01

    Very high energy ?-ray observations of distant active galactic nuclei (AGN) generally result in higher fluxes and harder spectra than expected, resulting in some tension with the level of the extragalactic background light (EBL). If hypothetical axions or axion-like particles (ALPs) were to exist, this tension could be relieved since the oscillation of photons to ALPs would mitigate the effects of EBL absorption and lead to softer inferred intrinsic AGN spectra. In this paper we consider the effect of photon-ALP mixing on observed spectra, including the photon-ALP mixing that would occur within AGN jets. We then simulate observations of three AGN with the Cherenkov Telescope Array (CTA), a next generation ?-ray telescope, to determine its prospects for detecting the signatures of photon-ALP mixing on the spectra. We conclude that prospects for CTA detecting these signatures or else setting limits on the ALP parameter space are quite promising. We find that prospects are improved if photon-ALP mixing within the jet is properly considered and that the best target for observations is PKS 2155-304.

  12. Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA)

    SciTech Connect (OSTI)

    Fonsart, Julien, E-mail: julien.fonsart@lrb.aphp.f [Universite Paris Descartes, Faculte de Pharmacie, Paris F-75006 (France); CNRS, UMR 7157, Paris F-75006 (France); INSERM, U705, Paris F-75006 (France); Assistance Publique-Hopitaux de Paris, Laboratoire de Toxicologie Biologique, Hopital Lariboisiere, Paris F-75010 (France); Menet, Marie-Claude [Universite Paris Descartes, Faculte de Pharmacie, Paris F-75006 (France); Universite Paris Descartes, Faculte de Pharmacie, Plateau Spectrometrie de Masse (IFR 71), Service de Chimie Analytique, Paris F-75006 (France); Debray, Marcel; Hirt, Deborah; Noble, Florence; Scherrmann, Jean-Michel; Decleves, Xavier [Universite Paris Descartes, Faculte de Pharmacie, Paris F-75006 (France); CNRS, UMR 7157, Paris F-75006 (France); INSERM, U705, Paris F-75006 (France)

    2009-12-15

    The use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) has increased in recent years; it can lead to life-threatening hyperthermia and serotonin syndrome. Human and rodent males appear to be more sensitive to acute toxicity than are females. MDMA is metabolized to five main metabolites by the enzymes CYP1A2, CYP2D and COMT. Little is presently known about sex-dependent differences in the pharmacokinetics of MDMA and its metabolites. We therefore analyzed MDMA disposition in male and female rats by measuring the plasma and urine concentrations of MDMA and its metabolites using a validated LC-MS method. MDA AUC{sub last} and C{sub max} were 1.6- to 1.7-fold higher in males than in females given MDMA (5 mg/kg sc), while HMMA C{sub max} and AUC{sub last} were 3.2- and 3.5-fold higher, respectively. MDMA renal clearance was 1.26-fold higher in males, and that of MDA was 2.2-fold higher. MDMA AUC{sub last} and t{sub 1/2} were 50% higher in females given MDMA (1 mg/kg iv). MDA C{sub max} and AUC{sub last} were 75-82% higher in males, with a 2.8-fold higher metabolic index. Finally, the AUC{sub last} of MDA was 0.73-fold lower in males given 1 mg/kg iv MDA. The volumes of distribution of MDMA and MDA at steady-state were similar in the two sexes. These data strongly suggest that differences in the N-demethylation of MDMA to MDA are major influences on the MDMA and MDA pharmacokinetics in male and female rats. Hence, males are exposed to significantly more toxic MDA, which could explain previously reported sexual dysmorphism in the acute effects and toxicity of MDMA in rats.

  13. X-ray Detections of Sub-millimetre Galaxies: Active Galactic Nuclei Versus Starburst Contribution

    E-Print Network [OSTI]

    Johnson, Seth P; Wang, Danial Q; Williams, Christina C; Scott, Kim S; Yun, Min S; Pope, Alexandra; Lowenthal, James; Aretxaga, Itziar; Hughes, David; Kim, M J; Kim, Sungeun; Tamura, Yoichi; Kohno, Kotaro; Ezawa, Hajime; Kawabe, Ryohei; Oshima, Tai; 10.1093/mnras/stt197

    2013-01-01

    We present a large-scale study of the X-ray properties and near-IR-to-radio SEDs of submillimetre galaxies (SMGs) detected at 1.1mm with the AzTEC instrument across a ~1.2 square degree area of the sky. Combining deep 2-4 Ms Chandra data with Spitzer IRAC/MIPS and VLA data within the GOODS-N/S and COSMOS fields, we find evidence for AGN activity in ~14 percent of 271 AzTEC SMGs, ~28 percent considering only the two GOODS fields. Through X-ray spectral modeling and SED fitting using Monte Carlo Markov Chain techniques to Siebenmorgen et al. (2004) (AGN) and Efstathiou et al. (2000) (starburst) templates, we find that while star formation dominates the IR emission, with SFRs ~100-1000 M_sun/yr, the X-ray emission for most sources is almost exclusively from obscured AGNs, with column densities in excess of 10^23 cm^-2. Only for ~6 percent of our sources do we find an X-ray-derived SFR consistent with NIR-to-radio SED derived SFRs. Inclusion of the X-ray luminosities as a prior to the NIR-to-radio SED effectively...

  14. Detecting Internet Outages with Active Probing USC/ISI Technical Report ISI-TR-672, May 2011

    E-Print Network [OSTI]

    Heidemann, John

    Detecting Internet Outages with Active Probing USC/ISI Technical Report ISI-TR-672, May 2011 Lin on the Internet, understanding its reliability is more important than ever. Network outages vary in scope and cause, from the intentional shutdown of the Egyptian Inter- net in February 2011, to outages caused

  15. Improved Design of Active Pixel CMOS Sensors for Charged Particle Detection

    SciTech Connect (OSTI)

    Deptuch, Grzegorz

    2007-11-12

    The Department of Energy (DOE) nuclear physics program requires developments in detector instrumentation electronics with improved energy, position and timing resolution, sensitivity, rate capability, stability, dynamic range, and background suppression. The current Phase-I project was focused on analysis of standard-CMOS photogate Active Pixel Sensors (APS) as an efficient solution to this challenge. The advantages of the CMOS APS over traditional hybrid approaches (i.e., separate detection regions bump-bonded to readout circuits) include greatly reduced cost, low power and the potential for vastly larger pixel counts and densities. However, challenges remain in terms of the signal-to-noise ratio (SNR) and readout speed (currently on the order of milliseconds), which is the major problem for this technology. Recent work has shown that the long readout time for photogate APS is due to the presence of (interface) traps at the semiconductor-oxide interface. This Phase-I work yielded useful results in two areas: (a) Advanced three-dimensional (3D) physics-based simulation models and simulation-based analysis of the impact of interface trap density on the transient charge collection characteristics of existing APS structures; and (b) Preliminary analysis of the feasibility of an improved photogate pixel structure (i.e., new APS design) with an induced electric field under the charge collecting electrode to enhance charge collection. Significant effort was dedicated in Phase-I to the critical task of implementing accurate interface trap models in CFDRC's NanoTCAD 3D semiconductor device-physics simulator. This resulted in validation of the new NanoTCAD models and simulation results against experimental (published) data, within the margin of uncertainty associated with obtaining device geometry, material properties, and experimentation details. Analyses of the new, proposed photogate APS design demonstrated several promising trends.

  16. AN AUGMENTED MULTI-TIERED CLASSIFIER FOR INSTANTANEOUS MULTI-MODAL VOICE ACTIVITY DETECTION

    E-Print Network [OSTI]

    Greenberg, Albert

    (green), and lip (blue) detected mouth cropped lips RGB histogram time-domain audio Fig. 1 starts or stops talking. Problems arise when the acoustic signal-to-noise ratio (SNR) decreases and informa- tion carried by an acoustic signal used to detect voice ac- tivity is lost, rapidly degrading

  17. Correlation and comparison of magnetic and electric detection of small intestinal electrical activity

    E-Print Network [OSTI]

    Wikswo, John

    Correlation and comparison of magnetic and electric detection of small intestinal electrical? Wikswo, Jr., and William 0. Richards. Correlation and comparison of magnetic and electric detection, the effects of an electrical insulator on the external electric and magnetic fields were studied in the rabbit

  18. Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: Role of ?-catenin/connexin43 association

    SciTech Connect (OSTI)

    Talhouk, Rabih S., E-mail: rtalhouk@aub.edu.lb [Department of Biology, Faculty of Arts and Sciences, American University of Beirut, P.O. Box 11-0236, Beirut (Lebanon); Fares, Mohamed-Bilal; Rahme, Gilbert J.; Hariri, Hanaa H.; Rayess, Tina; Dbouk, Hashem A.; Bazzoun, Dana; Al-Labban, Dania [Department of Biology, Faculty of Arts and Sciences, American University of Beirut, P.O. Box 11-0236, Beirut (Lebanon); El-Sabban, Marwan E., E-mail: me00@aub.edu.lb [Department of Anatomy, Cell Biology and Physiology, Faculty of Medicine, American University of Beirut, P.O. Box 11-0236, Beirut (Lebanon)

    2013-12-10

    Connexins (Cx), gap junction (GJ) proteins, are regarded as tumor suppressors, and Cx43 expression is often down regulated in breast tumors. We assessed the effect of Cx43 over-expression in 2D and 3D cultures of two breast adenocarcinoma cell lines: MCF-7 and MDA-MB-231. While Cx43 over-expression decreased proliferation of 2D and 3D cultures of MCF-7 by 56% and 80% respectively, MDA-MB-231 growth was not altered in 2D cultures, but exhibited 35% reduction in 3D cultures. C-terminus truncated Cx43 did not alter proliferation. Untransfected MCF-7 cells formed spherical aggregates in 3D cultures, and MDA-MB-231 cells formed stellar aggregates. However, MCF-7 cells over-expressing Cx43 formed smaller sized clusters and Cx43 expressing MDA-MB-231 cells lost their stellar morphology. Extravasation ability of both MCF-7 and MDA-MB-231 cells was reduced by 60% and 30% respectively. On the other hand, silencing Cx43 in MCF10A cells, nonneoplastic human mammary cell line, increased proliferation in both 2D and 3D cultures, and disrupted acinar morphology. Although Cx43 over-expression did not affect total levels of ?-catenin, ?-catenin and ZO-2, it decreased nuclear levels of ?-catenin in 2D and 3D cultures of MCF-7 cells, and in 3D cultures of MDA-MB-231 cells. Cx43 associated at the membrane with ?-catenin, ?-catenin and ZO-2 in 2D and 3D cultures of MCF-7 cells, and only in 3D conditions in MDA-MB-231 cells. This study suggests that Cx43 exerts tumor suppressive effects in a context-dependent manner where GJ assembly with ?-catenin, ?-catenin and ZO-2 may be implicated in reducing growth rate, invasiveness, and, malignant phenotype of 2D and 3D cultures of MCF-7 cells, and 3D cultures of MDA-MB-231 cells, by sequestering ?-catenin away from nucleus. - Highlights: • Cx43 over-expressing MCF-7 and MDA-MB-231 were grown in 2D and 3D cultures. • Proliferation and growth morphology were affected in a context dependent manner. • Extravasation ability of both MCF-7 and MDA-MB-231 cells was reduced. • Cx43-mediated gap junction complex assembly correlated with observed changes. • We propose that membranous Cx43 sequesters ?-catenin away from the nucleus.

  19. The bovine 5-? AMP activated protein kinase gene family: mapping and single nucleotide polymorphism detection 

    E-Print Network [OSTI]

    McKay, Stephanie Dawn

    2002-01-01

    The 5`-AMP-activated protein kinase (AMPK) family is an ancient stress response system whose primary function is regulation of cellular ATP. Activation of AMPK, which is instigated by environmental and nutritional stresses, ...

  20. Real-time detection of malicious network activity using stochastic models

    E-Print Network [OSTI]

    Jung, Jaeyeon, Ph. D. Massachusetts Institute of Technology

    2006-01-01

    This dissertation develops approaches to rapidly detect malicious network traffic including packets sent by portscanners and network worms. The main hypothesis is that stochastic models capturing a host's particular ...

  1. Mechanism of MDA5 Recognition of Short RNA Ligands and Crystal Structure of PepQ 

    E-Print Network [OSTI]

    Watts, Tylan Aubrey

    2013-05-16

    The innate immune pathways that stimulate the expression of cytokines and proapoptotic factors in response to infection are triggered by the activation of the cytosolic receptors retinoic acid-inducible gene I (RIG-I) and ...

  2. Active Contour Models: Application to Oral Lesion Detection in Color Images

    E-Print Network [OSTI]

    Hamarneh, Ghassan

    .g. classification of cancerous vs. non-cancerous lesions). In order to apply the conventional snake formulation of the patient's oral cavity as true-color digital images. Although complementary techniques exist, based e detection (segmentation) of color images of the oral mucosa is thus an important part of computer-aided oral

  3. Automatic Detection of Student Mental Models during Prior Knowledge Activation in MetaTutor

    E-Print Network [OSTI]

    Rus, Vasile

    to automatically detecting students' mental models in MetaTutor based on student-generated paragraphs during prior students. According to the experiments, a word-weighting method, which uses tf-idf values calculated from and combined with the machine learning algorithm of Logistic Regression. 1. Introduction We address

  4. Tracking Triadic Cardinality Distributions for Burst Detection in Social Activity Streams

    E-Print Network [OSTI]

    Lui, John C.S.

    due to this disorder [1]. Hence, detecting bursts in OSNs is an important task, both for OSN managers to monitor the operation status of an OSN, and for government agencies to anticipate any emer- gent social disorder. Typically, there are two types of user interactions in OSNs. First is the interaction between

  5. Optimal Time-Resource Allocation for Activity-Detection via Multimodal Sensing

    E-Print Network [OSTI]

    Annavaram, Murali

    is considered. The WBAN with heterogeneous sensors is deployed in a simple star topol- ogy with the fusion to each sensor is optimized to minimize the prob- ability of detection error at the fusion center ACM ICST 978-963-9799-41-7 ...$5.00. (A) (B) (C) Figure 1: The Nokia N95 cellphone fusion center (A

  6. Prolactin receptor attenuation induces zinc pool redistribution through ZnT2 and decreases invasion in MDA-MB-453 breast cancer cells

    SciTech Connect (OSTI)

    Bostanci, Zeynep; Alam, Samina; Soybel, David I.; Kelleher, Shannon L.

    2014-02-15

    Prolactin receptor (PRL-R) activation regulates cell differentiation, proliferation, cell survival and motility of breast cells. Prolactin (PRL) and PRL-R over-expression are strongly implicated in breast cancer, particularly contributing to tumor growth and invasion in the more aggressive estrogen-receptor negative (ER?) disease. PRL-R antagonists have been suggested as potential therapeutic agents; however, mechanisms through which PRL-R antagonists exert their actions are not well-understood. Zinc (Zn) is a regulatory factor for over 10% of the proteome, regulating critical cell processes such as proliferation, cell signaling, transcription, apoptosis and autophagy. PRL-R signaling regulates Zn metabolism in breast cells. Herein we determined effects of PRL-R attenuation on cellular Zn metabolism and cell function in a model of ER-, PRL-R over-expressing breast cancer cells (MDA-MB-453). PRL-R attenuation post-transcriptionally increased ZnT2 abundance and redistributed intracellular Zn pools into lysosomes and mitochondria. ZnT2-mediated lysosomal Zn sequestration was associated with reduced matrix metalloproteinase 2 (MMP-2) activity and decreased invasion. ZnT2-mediated Zn accumulation in mitochondria was associated with increased mitochondrial oxidation. Our results suggest that PRL-R antagonism in PRL-R over-expressing breast cancer cells may reduce invasion through the redistribution of intracellular Zn pools critical for cellular function. - Highlights: • PRL-R attenuation increased ZnT2 expression. • PRL-R attenuation increased lysosomal and mitochondrial Zn accumulation. • PRL-R attenuation decreased MMP-2 and invasion. • PRL-R antagonists may modulate lysosomal and mitochondrial Zn pools.

  7. Biomagnetic detection of gastric electrical activity in normal and vagotomized rabbits

    E-Print Network [OSTI]

    Wikswo, John

    electrical activity (GEA) in normal rabbits using a Superconducting QUantum Interference Device (SQUID muscle sources, they also have a magnetic field, and these may be recorded using a Superconduct- ing

  8. Characterization of Three-Dimensional-Integrated Active Pixel Sensor for X-Ray Detection

    E-Print Network [OSTI]

    Bautz, Marshall W.

    We have developed a back-illuminated active pixel sensor (APS) which includes an SOI readout circuit and a silicon diode detector array implemented in a separate high-resistivity wafer. Both are connected together using a ...

  9. Stellar Activity and its Implications for Exoplanet Detection on GJ 176

    E-Print Network [OSTI]

    Robertson, Paul; Henry, Gregory W; Cochran, William D; MacQueen, Phillip J; Williamson, Michael H

    2015-01-01

    We present an in-depth analysis of stellar activity and its effects on radial velocity (RV) for the M2 dwarf GJ 176 based on spectra taken over 10 years from the High Resolution Spectrograph on the Hobby-Eberly Telescope. These data are supplemented with spectra from previous observations with the HIRES and HARPS spectrographs, and V- and R-band photometry taken over 6 years at the Dyer and Fairborn observatories. Previous studies of GJ 176 revealed a super-Earth exoplanet in an 8.8-day orbit. However, the velocities of this star are also known to be contaminated by activity, particularly at the 39-day stellar rotation period. We have examined the magnetic activity of GJ 176 using the sodium I D lines, which have been shown to be a sensitive activity tracer in cool stars. In addition to rotational modulation, we see evidence of a long-term trend in our Na I D index, which may be part of a long-period activity cycle. The sodium index is well correlated with our RVs, and we show that this activity trend drives ...

  10. Detection of Hydrogen Spillover in Palladium-Modified Activated Carbon Fibers During Hydrogen Adsorption

    SciTech Connect (OSTI)

    Contescu, Cristian I; Brown, Craig; Liu, Yun; Bhat, Vinay V; Gallego, Nidia C

    2009-01-01

    Palladium-modified activated carbon fibers (Pd-ACF) are being evaluated for adsorptive hydrogen storage at near-ambient conditions because of their enhanced hydrogen uptake in comparison to Pd-free activated carbon fibers (ACF). The net uptake enhancement (at room temperature and 20 bar) is in excess of the amount corresponding to formation of Pd hydride, and is usually attributed to hydrogen spillover. In this paper, inelastic neutron scattering was used to demonstrate the formation of new C-H bonds in Pd-containing activated carbon fibers after exposure to hydrogen at 20 oC and 1.6 MPa, at the expense of physisorbed H2. This finding is a post-factum proof of the atomic nature of H species formed in presence of a Pd catalyst, and of their subsequent spillover and binding to the carbon support. Chemisorption of hydrogen may explain the reduction in hydrogen uptake from first to second adsorption cycle.

  11. DEVELOPMENT OF ADVANCED ALGORITHMS TO DETECT, CHARACTERIZE AND FORECAST SOLAR ACTIVITIES

    E-Print Network [OSTI]

    . This is critical for determining the non-potentiality of active regions. Solar flares are generated by the sudden earth space environment (so called space weather). In this dissertation, an automated solar flare machine) to forecast the occurrences of solar flares based on photospheric magnetic features. Logistic

  12. Toward Application of an Active Fence for Object Detection, Manipulation and Alignment on Conveyer Belt

    E-Print Network [OSTI]

    Belt Andon Salvarinov Shahram Payandeh Experimental Robotics Laboratory (ERL), School of Engineering This paper presents a novel approach for orienting an object on conveyer belt utilizing an Active Fence for each incoming randomly oriented object . Object alignment on conveyor belt by passive fences [2] is one

  13. Toward Application of an Active Fence for Object Detection, Manipulation and Alignment on Conveyer Belt

    E-Print Network [OSTI]

    Belt Andon Salvarinov Shahram Payandeh Experimental Robotics Laboratory ERL, School of Engineering This paper presents a novel approach for orienting an object on conveyer belt utilizing an Active Fence for each incoming randomly oriented object . Object alignment on conveyor belt by passive fences 2 is one

  14. An active state of the BL Lac Object Markarian 421 detected by INTEGRAL in April 2013

    E-Print Network [OSTI]

    Pian, E; Fiocchi, M; Bazzano, A; Foschini, L; Tavecchio, F; Bianchin, V; Boissay, R; Castignani, G; Ferrigno, C; Raiteri, C M; Villata, M; Beckmann, V; D'Ammando, F; Hudec, R; Malaguti, G; Maraschi, L; Pursimo, T; Romano, P; Soldi, S; Stamerra, A; Treves, A; Ubertini, P; Vercellone, S; Walter, R

    2013-01-01

    (abridged) Multi-wavelength variability of blazars offers effective insight into the mechanisms through which energy is propagated from the center down the jet. In this context, we activated INTEGRAL observations of the blazar Markarian 421 in an active state on 16-21 April 2013, and complemented them with Fermi-LAT data. We obtained well sampled optical, soft and hard X-ray light curves that show the presence of two flares, the first one reaching a brighter maximum than the second one at X-rays. The average flux in the 20-100 keV range is 9.1e-11 cgs and the nuclear average apparent magnitude, corrected for Galactic extinction, is V ~ 12.2. In the time-resolved JEMX+IBIS spectra we see a change of spectral slope at an energy that correlates with flux, as expected in refreshed energy injections in a population of electrons that cool thereafter via synchrotron radiation. During the observation, the variability level increases monotonically from the optical to the hard X-rays, and the cross-correlation analysis...

  15. Parametric Evaluation of Active Neutron Interrogation for the Detection of Shielded Highly-Enriched Uranium in the Field

    SciTech Connect (OSTI)

    D. L. Chcihester; E. H. Seabury; S. J. Thompson; R. R. C. Clement

    2011-10-01

    Parametric studies using numerical simulations are being performed to assess the performance capabilities and limits of active neutron interrogation for detecting shielded highly enriched uranium (HEU). Varying the shield material, HEU mass, HEU depth inside the shield, and interrogating neutron source energy, the simulations account for both neutron and photon emission signatures from the HEU with resolution in both energy and time. The results are processed to represent different irradiation timing schemes and several different classes of radiation detectors, and evaluated using a statistical approach considering signal intensity over background. This paper describes the details of the modeling campaign and some preliminary results, weighing the strengths of alternative measurement approaches for the different irradiation scenarios.

  16. Excavation of MDA B

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansasCommunitiesof Energy8) Wigner HomeExample Cleanupin this issueu t

  17. MDA - 0112.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture |0396THIN^J

  18. MDA - 0203.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture |0396THIN^J2nd Quarter

  19. MDA - 0206.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture |0396THIN^J2nd Quarter3rd

  20. MDA - 0212.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture |0396THIN^J2nd Quarter3rd1st

  1. MDA - 0303.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture |0396THIN^J2nd

  2. MDA - 0306.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture

  3. MDA - 0312.PDF

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture3, BPA earned net revenues of

  4. MDA0006.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture3, BPA earned net revenues

  5. MDA0012.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture3, BPA earned net revenues1st

  6. MDA0103.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture3, BPA earned net

  7. A ROBUST ABSOLUTE DETECTION EFFICIENCY CALIBRATION METHOD UTILIZING BETA/GAMMA COINCIDENCE SIGNATURES AND ISOTOPICALLY PURIFIED NEUTRON ACTIVATED RADIOXENON ISOTOPES

    SciTech Connect (OSTI)

    McIntyre, Justin I.; Cooper, Matthew W.; Ely, James H.; Haas, Derek A.; Schrom, Brian T.

    2012-09-21

    Efforts to calibrate the absolute efficiency of gas cell radiations detectors have utilized a number of methodologies which allow adequate calibration but are time consuming and prone to a host of difficult-to-determine uncertainties. A method that extrapolates the total source strength from the measured beta and gamma gated beta coincidence signal was developed in the 1960’s and 1970’s. It has become clear that it is possible to achieve more consistent results across a range of isotopes and a range of activities using this method. Even more compelling is the ease with which this process can be used on routine samples to determine the total activity present in the detector. Additionally, recent advances in the generation of isotopically pure radioxenon samples of Xe-131m, Xe-133, and Xe-135 have allowed these measurement techniques to achieve much better results than would have been possible before when using mixed isotopic radioxenon source. This paper will discuss the beta/gamma absolute detection efficiency technique that utilizes several of the beta-gamma decay signatures to more precisely determine the beta and gamma efficiencies. It will than compare these results with other methods using pure sources of Xe-133, Xe-131m, and Xe-135 and a Xe-133/Xe-133m mix.

  8. Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells

    SciTech Connect (OSTI)

    Curry, Merril C.; Peters, Amelia A.; Kenny, Paraic A.; Roberts-Thomson, Sarah J.; Monteith, Gregory R.

    2013-05-10

    Highlights: •Some clinical breast cancers are associated with MCU overexpression. •MCU silencing did not alter cell death initiated with the Bcl-2 inhibitor ABT-263. •MCU silencing potentiated caspase-independent cell death initiated by ionomycin. •MCU silencing promoted ionomycin-mediated cell death without changes in bulk Ca{sup 2+}. -- Abstract: The mitochondrial calcium uniporter (MCU) transports free ionic Ca{sup 2+} into the mitochondrial matrix. We assessed MCU expression in clinical breast cancer samples using microarray analysis and the consequences of MCU silencing in a breast cancer cell line. Our results indicate that estrogen receptor negative and basal-like breast cancers are characterized by elevated levels of MCU. Silencing of MCU expression in the basal-like MDA-MB-231 breast cancer cell line produced no change in proliferation or cell viability. However, distinct consequences of MCU silencing were seen on cell death pathways. Caspase-dependent cell death initiated by the Bcl-2 inhibitor ABT-263 was not altered by MCU silencing; whereas caspase-independent cell death induced by the calcium ionophore ionomycin was potentiated by MCU silencing. Measurement of cytosolic Ca{sup 2+} levels showed that the promotion of ionomycin-induced cell death by MCU silencing occurs independently of changes in bulk cytosolic Ca{sup 2+} levels. This study demonstrates that MCU overexpression is a feature of some breast cancers and that MCU overexpression may offer a survival advantage against some cell death pathways. MCU inhibitors may be a strategy to increase the effectiveness of therapies that act through the induction of caspase-independent cell death pathways in estrogen receptor negative and basal-like breast cancers.

  9. Active site mapping of iterative polyketide synthases and the detection of polyketide intermediates using high- resolution Fourier Transform mass spectrometry

    E-Print Network [OSTI]

    Meehan, Michael Joseph

    2009-01-01

    be ejected during thermal activation methods and that thisPEA is accomplished using thermal activation methods.are a large number of thermal activation methods that could

  10. Final report on passive and active low-frequency electromagnetic spectroscopy for airborne detection of underground facilities

    SciTech Connect (OSTI)

    SanFilipo, Bill

    2000-04-01

    The objective of this program is to perform research to advance the science in the application of both passive and active electromagnetic measurement techniques for the detection and spatial delineation of underground facilities. Passive techniques exploit the electromagnetic fields generated by electrical apparatus within the structure, including generators, motors, power distribution circuitry, as well as communications hardware and similar electronics equipment. Frequencies monitored are generally in the audio range (60-20,000 Hz), anticipating strong sources associated with normal AC power (i.e., 50 or 60 Hz and associated harmonics), and low frequency power from broad-band sources such as switching circuits. Measurements are made using receiver induction coils wired to electronics that digitize and record the voltage induced by the time varying magnetic fields. Active techniques employ electromagnetic field transmitters in the form of AC current carrying loops also in the audio frequency range, and receiving coils that measure the resultant time varying magnetic fields. These fields are perturbed from those expected in free space by any conductive material in the vicinity of the coils, including the ground, so that the total measured field is comprised of the primary free-space component and the secondary scattered component. The latter can be further delineated into an average background field (uniform conductive half-space earth) and anomalous field associated with heterogeneous zones in the earth, including both highly conductive objects such as metallic structures as well as highly resistive structures such as empty voids corresponding to rooms or tunnels. Work performed during Phase I included the development of the prototype GEM-2H instrumentation, collection of data at several test sites in the passive mode and a single site in the active mode, development of processing and interpretation software. The technical objectives of Phase II were to: (1) continue to develop and improve EM instruments; (2) develop new software for analysis and inversion of electromagnetic induction measurements for both passive and active surveys; and (3) Perform experiments to test EM induction methodology.

  11. Assessment of inhalation and ingestion doses from exposure to radon gas using passive and active detecting techniques

    SciTech Connect (OSTI)

    Ismail, A. H.; Jafaar, M. S.

    2011-07-01

    The aim of this study was to assess an environmental hazard of radon exhalation rate from the samples of soil and drinking water in selected locations in Iraqi Kurdistan, passive (CR-39NTDs) and active (RAD7) detecting techniques has been employed. Long and short term measurements of emitted radon concentrations were estimated for 124 houses. High and lower radon concentration in soil samples was in the cities of Hajyawa and Er. Tyrawa, respectively. Moreover, for drinking water, high and low radon concentration was in the cities of Similan and Kelak, respectively. A comparison between our results with that mentioned in international reports had been done. Average annual dose equivalent to the bronchial epithelium, stomach and whole body in the cities of Kelak and Similan are estimated, and it was varied from 0.04{+-}0.01 mSv to 0.547{+-}0.018 mSv, (2.832{+-}0.22)x10{sup -5} to (11.972{+-}2.09)x10{sup -5} mSv, and (0.056 {+-}0.01) x10{sup -5} to (0.239{+-}0.01)x10{sup -5} mSv, respectively. This indicated that the effects of dissolved radon on the bronchial epithelium are much than on the stomach and whole body. (authors)

  12. Laboratory and Field Testing of Commercially Available Detectors for the Identification of Chemicals of Interest in the Nuclear Fuel Cycle for the Detection of Undeclared Activities

    SciTech Connect (OSTI)

    Carla Miller; Mary Adamic; Stacey Barker; Barry Siskind; Joe Brady; Warren Stern; Heidi Smartt; Mike McDaniel; Mike Stern; Rollin Lakis

    2014-07-01

    Traditionally, IAEA inspectors have focused on the detection of nuclear indicators as part of infield inspection activities. The ability to rapidly detect and identify chemical as well as nuclear signatures can increase the ability of IAEA inspectors to detect undeclared activities at a site. Identification of chemical indicators have been limited to use in the analysis of environmental samples. Although IAEA analytical laboratories are highly effective, environmental sample processing does not allow for immediate or real-time results to an IAEA inspector at a facility. During a complementary access inspection, under the Additional Protocol, the use of fieldable technologies that can quickly provide accurate information on chemicals that may be indicative of undeclared activities can increase the ability of IAEA to effectively and efficiently complete their mission. The Complementary Access Working Group (CAWG) is a multi-laboratory team with members from Brookhaven National Laboratory, Idaho National Laboratory, Los Alamos National Laboratory, and Sandia National Laboratory. The team identified chemicals at each stage of the nuclear fuel cycle that may provide IAEA inspectors with indications that proliferation activities may be occurring. The group eliminated all indicators related to equipment, technology and training, developing a list of by-products/effluents, non-nuclear materials, nuclear materials, and other observables. These proliferation indicators were prioritized based on detectability from a conduct of operations (CONOPS) perspective of a CA inspection (for example, whether an inspector actually can access the S&O or whether it is in process with no physical access), and the IAEA’s interest in the detection technology in conjunction with radiation detectors. The list was consolidated to general categories (nuclear materials from a chemical detection technique, inorganic chemicals, organic chemicals, halogens, and miscellaneous materials). The team then identified commercial off the shelf (COTS) chemical detectors that may detect the chemicals of interest. Three chemical detectors were selected and tested both in laboratory settings and in field operations settings at Idaho National Laboratory. The instruments selected are: Thermo Scientific TruDefender FT (FTIR), Thermo Scientific FirstDefender RM (Raman), and Bruker Tracer III SD (XRF). Functional specifications, operability, and chemical detectability, selectivity, and limits of detection were determined. Results from the laboratory and field tests will be presented. This work is supported by the Next Generation Safeguards Initiative, Office of Nonproliferation and International Security, National Nuclear Security Administration.

  13. SGR J1550-5418 BURSTS DETECTED WITH THE FERMI GAMMA-RAY BURST MONITOR DURING ITS MOST PROLIFIC ACTIVITY

    SciTech Connect (OSTI)

    Van der Horst, A. J.; Finger, M. H. [Universities Space Research Association, NSSTC, Huntsville, AL 35805 (United States); Kouveliotou, C. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gorgone, N. M. [Connecticut College, New London, CT 06320 (United States); Kaneko, Y.; Goegues, E.; Lin, L. [Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I -Tuzla, Istanbul 34956 (Turkey); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Guiriec, S.; Bhat, P. N.; Chaplin, V. L.; Goldstein, A. [University of Alabama, Huntsville, CSPAR, Huntsville, AL 35805 (United States); Granot, J. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); Watts, A. L. [Astronomical Institute 'Anton Pannekoek', University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Bissaldi, E.; Gruber, D. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, 85748 Garching (Germany); Gehrels, N.; Harding, A. K. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Gibby, M. H.; Giles, M. M., E-mail: A.J.VanDerHorst@uva.nl [Jacobs Technology, Inc., Huntsville, AL (United States); and others

    2012-04-20

    We have performed detailed temporal and time-integrated spectral analysis of 286 bursts from SGR J1550-5418 detected with the Fermi Gamma-ray Burst Monitor (GBM) in 2009 January, resulting in the largest uniform sample of temporal and spectral properties of SGR J1550-5418 bursts. We have used the combination of broadband and high time-resolution data provided with GBM to perform statistical studies for the source properties. We determine the durations, emission times, duty cycles, and rise times for all bursts, and find that they are typical of SGR bursts. We explore various models in our spectral analysis, and conclude that the spectra of SGR J1550-5418 bursts in the 8-200 keV band are equally well described by optically thin thermal bremsstrahlung (OTTB), a power law (PL) with an exponential cutoff (Comptonized model), and two blackbody (BB) functions (BB+BB). In the spectral fits with the Comptonized model, we find a mean PL index of -0.92, close to the OTTB index of -1. We show that there is an anti-correlation between the Comptonized E{sub peak} and the burst fluence and average flux. For the BB+BB fits, we find that the fluences and emission areas of the two BB functions are correlated. The low-temperature BB has an emission area comparable to the neutron star surface area, independent of the temperature, while the high-temperature BB has a much smaller area and shows an anti-correlation between emission area and temperature. We compare the properties of these bursts with bursts observed from other SGR sources during extreme activations, and discuss the implications of our results in the context of magnetar burst models.

  14. Detecting estrogenic activity in water samples with estrogen-sensitive yeast cells using spectrophotometry and fluorescence microscopy

    E-Print Network [OSTI]

    Wozei, E.; Holman, H-Y.N.; Hermanowicz, S.W.; Borglin S.

    2006-01-01

    ethinylestradiole to sewage sludge." Chemosphere 56(9):Compounds in Wastewater, Sludge-Treatment Processes, andchemicals in activated sludge treatment works [Review]."

  15. The Origin of Double-Peaked Narrow Lines in Active Galactic Nuclei I: Very Large Array Detections of Dual AGNs and AGN Outflows

    E-Print Network [OSTI]

    Müller-Sanchez, Francisco; Nevin, Rebecca; Barrows, R Scott; Cooper, Michael C; Greene, Jenny E

    2015-01-01

    We have examined a subset of 18 active galactic nuclei (AGNs) drawn from a sample of 81 galaxies that possess double-peaked narrow optical emission line spectra in the Sloan Digital Sky Survey, have two optical AGN emission components separated by >0.2", and are detected in the Faint Images of the Radio Sky at Twenty-centimeters survey. Without follow-up observations, the sources of the double-peaked narrow emission lines are uncertain, and may be produced by kpc-scale separation dual active supermassive black holes, AGN outflows, or disk rotation. In this work, we propose a new methodology to characterize double-peaked narrow emission-line galaxies based on optical long-slit spectroscopy and high resolution multi-band Very Large Array observations. The nature of the radio emission in the sample galaxies is varied. Of the 18 galaxies, we detect two compact flat-spectrum radio cores with projected spatial separations on the sky between 0.6-1.6 kpc in three galaxies: J1023+3243, J1158+3231, and J1623+0808. The ...

  16. VERITAS detection of $\\gamma$-ray flaring activity from the BL Lac object 1ES 1727+502 during bright moonlight observations

    E-Print Network [OSTI]

    Archambault, S; Beilicke, M; Benbow, W; Bird, R; Biteau, J; Bouvier, A; Bugaev, V; Cardenzana, J V; Cerruti, M; Chen, X; Ciupik, L; Connolly, M P; Cui, W; Dickinson, H J; Dumm, J; Eisch, J D; Errando, M; Falcone, A; Feng, Q; Finley, J P; Fleischhack, H; Fortin, P; Fortson, L; Furniss, A; Gillanders, G H; Griffin, S; Griffiths, S T; Grube, J; Gyuk, G; Håkansson, N; Hanna, D; Holder, J; Humensky, T B; Johnson, C A; Kaaret, P; Kar, P; Kertzman, M; Khassen, Y; Kieda, D; Krause, M; Krennrich, F; Kumar, S; Lang, M J; Maier, G; McArthur, S; McCann, A; Meagher, K; Millis, J; Moriarty, P; Mukherjee, R; Nieto, D; de Bhróithe, A O'Faoláin; Ong, R A; Otte, A N; Park, N; Pohl, M; Popkow, A; Prokoph, H; Pueschel, E; Quinn, J; Ragan, K; Reyes, L C; Reynolds, P T; Richards, G T; Roache, E; Santander, M; Sembroski, G H; Shahinyan, K; Smith, A W; Staszak, D; Telezhinsky, I; Tucci, J V; Tyler, J; Varlotta, A; Vincent, S; Wakely, S P; Weinstein, A; Welsing, R; Wilhelm, A; Williams, D A; Zitzer, B; Hughes, Z D

    2015-01-01

    During moonlit nights, observations with ground-based Cherenkov telescopes at very high energies (VHE, $E>100$ GeV) are constrained since the photomultiplier tubes (PMTs) in the telescope camera are extremely sensitive to the background moonlight. Observations with the VERITAS telescopes in the standard configuration are performed only with a moon illumination less than 35$\\%$ of full moon. Since 2012, the VERITAS collaboration has implemented a new observing mode under bright moonlight, by either reducing the voltage applied to the PMTs (reduced-high-voltage configuration, RHV), or by utilizing UV-transparent filters. While these operating modes result in lower sensitivity and increased energy thresholds, the extension of the available observing time is useful for monitoring variable sources such as blazars and sources requiring spectral measurements at the highest energies. In this paper we report the detection of $\\gamma$-ray flaring activity from the BL Lac object 1ES 1727+502 during RHV observations. Thi...

  17. Activation detector

    DOE Patents [OSTI]

    Bell, Zane William (Oak Ridge, TN) [Oak Ridge, TN; Boatner, Lynn Allen (Oak Ridge, TN) [Oak Ridge, TN

    2009-12-08

    A method of detecting an activator, the method including impinging with an activator a receptor material lacking a photoluminescent material and generating a by-product of a radioactive decay due to the activator impinging the reeptor material. The method further including, generating light from the by-product via the Cherenkov effect and identifying a characteristic of the activator based on the light.

  18. Radon detection

    DOE Patents [OSTI]

    MacArthur, D.W.; Allander, K.S.; Bounds, J.A.

    1994-01-25

    A detector for atmospheric radon using a long range alpha detector as its sensing element is described. An electrostatic filter removes ions from ambient air, while allowing radon atoms to pass into a decay cavity. Here, radon atoms are allowed to decay, creating air ions. These air ions are drawn by a fan through a second electrostatic filter which can be activated or deactivated, and into the long range alpha detector. With the second electrostatic filter activated, no air ions are allowed to pass, and the signal output from the long range alpha detector consists of only the electronic background. With the second electrostatic filter deactivated, air ions and cosmic rays will be detected. The cosmic ray contribution can be minimized by shielding. 3 figures.

  19. Radon detection

    DOE Patents [OSTI]

    MacArthur, Duncan W. (Los Alamos, NM); Allander, Krag S. (Ojo Caliente, NM); Bounds, John A. (Los Alamos, NM)

    1994-01-01

    A detector for atmospheric radon using a long range alpha detector as its sensing element. An electrostatic filter removes ions from ambient air, while allowing radon atoms to pass into a decay cavity. Here, radon atoms are allowed to decay, creating air ions. These air ions are drawn by a fan through a second electrostatic filter which can be activated or deactivated, and into the long range alpha detector. With the second electrostatic filter activated, no air ions are allowed to pass, and the signal output from the long range alpha detector consists of only the electronic background. With the second electrostatic filter deactivated, air ions and cosmic rays will be detected. The cosmic ray contribution can be minimized by shielding.

  20. Remote detection of fissile material : Cherenkov counters for gamma detection

    E-Print Network [OSTI]

    Erickson, Anna S

    2011-01-01

    The need for large-size detectors for long-range active interrogation (Al) detection has generated interest in water-based detector technologies. AI is done using external radiation sources to induce fission and to detect, ...

  1. Methods, microfluidic devices, and systems for detection of an...

    Office of Scientific and Technical Information (OSTI)

    and systems for detection of an active enzymatic agent Embodiments of the present invention provide methods, microfluidic devices, and systems for the detection of an active...

  2. Quantitative Assessment of Detection Frequency for the INL Ambient Air Monitoring Network

    SciTech Connect (OSTI)

    A. Jeffrey Sondrup; Arthur S. Rood

    2014-11-01

    A quantitative assessment of the Idaho National Laboratory (INL) air monitoring network was performed using frequency of detection as the performance metric. The INL air monitoring network consists of 37 low-volume air samplers in 31 different locations. Twenty of the samplers are located on INL (onsite) and 17 are located off INL (offsite). Detection frequencies were calculated using both BEA and ESER laboratory minimum detectable activity (MDA) levels. The CALPUFF Lagrangian puff dispersion model, coupled with 1 year of meteorological data, was used to calculate time-integrated concentrations at sampler locations for a 1-hour release of unit activity (1 Ci) for every hour of the year. The unit-activity time-integrated concentration (TICu) values were calculated at all samplers for releases from eight INL facilities. The TICu values were then scaled and integrated for a given release quantity and release duration. All facilities modeled a ground-level release emanating either from the center of the facility or at a point where significant emissions are possible. In addition to ground-level releases, three existing stacks at the Advanced Test Reactor Complex, Idaho Nuclear Technology and Engineering Center, and Material and Fuels Complex were also modeled. Meteorological data from the 35 stations comprising the INL Mesonet network, data from the Idaho Falls Regional airport, upper air data from the Boise airport, and three-dimensional gridded data from the weather research forecasting model were used for modeling. Three representative radionuclides identified as key radionuclides in INL’s annual National Emission Standards for Hazardous Air Pollutants evaluations were considered for the frequency of detection analysis: Cs-137 (beta-gamma emitter), Pu-239 (alpha emitter), and Sr-90 (beta emitter). Source-specific release quantities were calculated for each radionuclide, such that the maximum inhalation dose at any publicly accessible sampler or the National Emission Standards for Hazardous Air Pollutants maximum exposed individual location (i.e., Frenchman’s Cabin) was no more than 0.1 mrem yr–1 (i.e., 1% of the 10 mrem yr–1 standard). Detection frequencies were calculated separately for the onsite and offsite monitoring network. As expected, detection frequencies were generally less for the offsite sampling network compared to the onsite network. Overall, the monitoring network is very effective at detecting the potential releases of Cs-137 or Sr-90 from all sources/facilities using either the ESER or BEA MDAs. The network was less effective at detecting releases of Pu-239. Maximum detection frequencies for Pu-239 using ESER MDAs ranged from 27.4 to 100% for onsite samplers and 3 to 80% for offsite samplers. Using BEA MDAs, the maximum detection frequencies for Pu-239 ranged from 2.1 to 100% for onsite samplers and 0 to 5.9% for offsite samplers. The only release that was not detected by any of the samplers under any conditions was a release of Pu-239 from the Idaho Nuclear Technology and Engineering Center main stack (CPP-708). The methodology described in this report could be used to improve sampler placement and detection frequency, provided clear performance objectives are defined.

  3. Composition for detecting uranyl

    DOE Patents [OSTI]

    Baylor, Lewis C. (North Augusta, SC); Stephens, Susan M. (Athens, GA)

    1995-01-01

    A composition for detecting the presence and concentration of a substance such as uranyl, comprising an organohalide covalently bonded to an indicator for said substance. The composition has at least one active OH site for forming a complex with the substance to be detected. The composition is made by reacting equimolar amounts of the indicator and the organohalide in a polar organic solvent. The absorbance spectrum of the composition-uranyl complex is shifted with respect to the absorbance spectrum of the indicator-uranyl complex, to provide better spectral resolution for detecting uranyl.

  4. 13C magnetic resonance spectroscopy measurements with hyperpolarized [1-13C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo

    E-Print Network [OSTI]

    Dzien, Piotr; Tee, Sui-Seng; Kettunen, Mikko I.; Lyons, Scott K.; Larkin, Timothy J.; Timm, Kerstin N.; Hu, De-En; Wright, Alan; Rodrigues, Tiago B.; Serrao, Eva M.; Marco-Rius, Irene; Mannion, Elizabeth; D‘Santos, Paula; Kennedy, Brett W.; Brindle, Kevin M.

    2015-01-01

    ] pyruvate, increased approximately 1.9 –fold (1.9 ± 0.6; SD, p fusion protein can be detected... ) and similar fluorescent reporter genes, is comparable to that of the widely used bioluminescence reporter, Firefly luciferase (1.65 kbp). A compact reporter size is an advantage when the payload constraints of delivery vectors are considered. Since...

  5. Comparison of the MODIS Active Fire Product and Burned Area Product in Detecting Fire Affected Pixels in the Ecosystems of Belize 2003 - 2009 

    E-Print Network [OSTI]

    van, Warmerdam

    2010-11-24

    The MODIS Active Fire Product (AFP) and the Burned Area Product (BAP) were used to analyze the spatial and temporal distribution of fire affected pixels in the ecosystems of Belize from 2003-2009. There was an overall ...

  6. detonation detection

    National Nuclear Security Administration (NNSA)

    Satellite Carrying NNSA-provided Nuclear Detonation Detection Sensors http:www.nnsa.energy.govmediaroompressreleasesafsatellite

  7. Nucleic acid detection kits

    DOE Patents [OSTI]

    Hall, Jeff G.; Lyamichev, Victor I.; Mast, Andrea L.; Brow, Mary Ann; Kwiatkowski, Robert W.; Vavra, Stephanie H.

    2005-03-29

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample.

  8. Solar system fault detection

    DOE Patents [OSTI]

    Farrington, R.B.; Pruett, J.C. Jr.

    1984-05-14

    A fault detecting apparatus and method are provided for use with an active solar system. The apparatus provides an indication as to whether one or more predetermined faults have occurred in the solar system. The apparatus includes a plurality of sensors, each sensor being used in determining whether a predetermined condition is present. The outputs of the sensors are combined in a pre-established manner in accordance with the kind of predetermined faults to be detected. Indicators communicate with the outputs generated by combining the sensor outputs to give the user of the solar system and the apparatus an indication as to whether a predetermined fault has occurred. Upon detection and indication of any predetermined fault, the user can take appropriate corrective action so that the overall reliability and efficiency of the active solar system are increased.

  9. Solar system fault detection

    DOE Patents [OSTI]

    Farrington, Robert B. (Wheatridge, CO); Pruett, Jr., James C. (Lakewood, CO)

    1986-01-01

    A fault detecting apparatus and method are provided for use with an active solar system. The apparatus provides an indication as to whether one or more predetermined faults have occurred in the solar system. The apparatus includes a plurality of sensors, each sensor being used in determining whether a predetermined condition is present. The outputs of the sensors are combined in a pre-established manner in accordance with the kind of predetermined faults to be detected. Indicators communicate with the outputs generated by combining the sensor outputs to give the user of the solar system and the apparatus an indication as to whether a predetermined fault has occurred. Upon detection and indication of any predetermined fault, the user can take appropriate corrective action so that the overall reliability and efficiency of the active solar system are increased.

  10. Spectroscopic Detection of Pathogens

    SciTech Connect (OSTI)

    ALAM,M. KATHLEEN; TIMLIN,JERILYN A.; MARTIN,LAURA E.; HJELLE,DRIAN; LYONS,RICK; GARRISON,KRISTIN

    2000-11-01

    The goal of this LDRD Research project was to provide a preliminary examination of the use of infrared spectroscopy as a tool to detect the changes in cell cultures upon activation by an infectious agent. Due to a late arrival of funding, only 5 months were available to transfer and setup equipment at UTTM,develop cell culture lines, test methods of in-situ activation and collect kinetic data from activated cells. Using attenuated total reflectance (ATR) as a sampling method, live cell cultures were examined prior to and after activation. Spectroscopic data were collected from cells immediately after activation in situ and, in many cases for five successive hours. Additional data were collected from cells activated within a test tube (pre-activated), in both transmission mode as well as in ATR mode. Changes in the infrared data were apparent in the transmission data collected from the pre-activated cells as well in some of the pre-activated ATR data. Changes in the in-situ activated spectral data were only occasionally present due to (1) the limited time cells were studied and (2) incomplete activation. Comparison of preliminary data to infrared bands reported in the literature suggests the primary changes seen are due an increase in ribonucleic acid (RNA) production. This work will be continued as part of a 3 year DARPA grant.

  11. Detection device for hazardous materials

    DOE Patents [OSTI]

    Partin, Judy K. (Idaho Falls, ID); Grey, Alan E. (Idaho Falls, ID)

    1994-01-01

    A detection device that is activated by the interaction of a hazardous chcal with a coating interactive with said chemical on an optical fiber thereby reducing the amount of light passing through the fiber to a light detector. A combination of optical filters separates the light into a signal beam and a reference beam which after detection, appropriate amplification, and comparison with preset internal signals, activates an alarm means if a predetermined level of contaminant is observed.

  12. Detection device for hazardous materials

    DOE Patents [OSTI]

    Partin, Judy K.; Grey, Alan E.

    1994-04-05

    A detection device that is activated by the interaction of a hazardous chcal with a coating interactive with said chemical on an optical fiber thereby reducing the amount of light passing through the fiber to a light detector. A combination of optical filters separates the light into a signal beam and a reference beam which after detection, appropriate amplification, and comparison with preset internal signals, activates an alarm means if a predetermined level of contaminant is observed.

  13. Fingerprint detection

    DOE Patents [OSTI]

    Saunders, George C. (Rt. 1, Box 428B, Espanola, NM 87532)

    1992-01-01

    A method for detection and visualization of latent fingerprints is provided and includes contacting a substrate containing a latent print thereon with a colloidal metal composition for time sufficient to allow reaction of said colloidal metal composition with said latent print, and preserving or recording the observable print. Further, the method for detection and visualization of latent fingerprints can include contacting the metal composition-latent print reaction product with a secondary metal-containing solution for time sufficient to allow precipitation of said secondary metal thereby enhancing the visibility of the latent print, and preserving or recording the observable print.

  14. Detection device

    DOE Patents [OSTI]

    Smith, Jay E. (Pittsburgh, PA)

    1984-01-01

    The present invention is directed to a detection device comprising: (1) an entrance chamber, (2) a central chamber, and (3) an exit chamber. The central chamber includes an ionizing gas, anode, and means for connecting the anode with an external power supply and pulse counter.

  15. MDA0106-Revised for SFAS 133.PDF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACTThousandReport) | SciTech ConnectFuture3, BPA earned net3rd Quarter

  16. Detection Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalent BondingMeeting |Design CompetitionsFuelof 12Detecting

  17. Spectroscopic detection

    DOE Patents [OSTI]

    Woskov, Paul P. (Bedford, MA); Hadidi, Kamal (Cambridge, MA)

    2003-01-01

    In embodiments, spectroscopic monitor monitors modulated light signals to detect low levels of contaminants and other compounds in the presence of background interference. The monitor uses a spectrometer that includes a transmissive modulator capable of causing different frequency ranges to move onto and off of the detector. The different ranges can include those with the desired signal and those selected to subtract background contributions from those with the desired signal. Embodiments of the system are particularly useful for monitoring metal concentrations in combustion effluent.

  18. Smoke detection

    SciTech Connect (OSTI)

    Warmack, Robert J. Bruce; Wolf, Dennis A.; Frank, Steven Shane

    2015-10-27

    Various apparatus and methods for smoke detection are disclosed. In one embodiment, a method of training a classifier for a smoke detector comprises inputting sensor data from a plurality of tests into a processor. The sensor data is processed to generate derived signal data corresponding to the test data for respective tests. The derived signal data is assigned into categories comprising at least one fire group and at least one non-fire group. Linear discriminant analysis (LDA) training is performed by the processor. The derived signal data and the assigned categories for the derived signal data are inputs to the LDA training. The output of the LDA training is stored in a computer readable medium, such as in a smoke detector that uses LDA to determine, based on the training, whether present conditions indicate the existence of a fire.

  19. Smoke detection

    SciTech Connect (OSTI)

    Warmack, Robert J Bruce; Wolf, Dennis A.; Frank, Steven Shane

    2015-11-05

    Various apparatus and methods for smoke detection are disclosed. In one embodiment, a method of training a classifier for a smoke detector comprises inputting sensor data from a plurality of tests into a processor. The sensor data is processed to generate derived signal data corresponding to the test data for respective tests. The derived signal data is assigned into categories comprising at least one fire group and at least one non-fire group. Linear discriminant analysis (LDA) training is performed by the processor. The derived signal data and the assigned categories for the derived signal data are inputs to the LDA training. The output of the LDA training is stored in a computer readable medium, such as in a smoke detector that uses LDA to determine, based on the training, whether present conditions indicate the existence of a fire.

  20. Support Vector Clustering for Brain Activation Detection

    E-Print Network [OSTI]

    are mapped from their original feature space to a very high dimensional kernel space. By finding a compact are scattered in certain shapes, such as hyper-spherical (when using Euclidean distance) and hyper such as margin maximization and kernel substitution for classifying data in a high dimensional kernel space

  1. Nucleic acid detection assays

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann; Dahlberg, James E.

    2005-04-05

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  2. Nucleic acid detection compositions

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor I. (Madison, WI); Brow, Mary Ann (Madison, WI); Dahlberg, James L. (Madison, WI)

    2008-08-05

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  3. Arsenic activation neutron detector

    DOE Patents [OSTI]

    Jacobs, Eddy L. (Albuquerque, NM)

    1981-01-01

    A detector of bursts of neutrons from a deuterium-deuteron reaction includes a quantity of arsenic adjacent a gamma detector such as a scintillator and photomultiplier tube. The arsenic is activated by the 2.5 Mev neutrons to release gamma radiation which is detected to give a quantitative representation of detected neutrons.

  4. Arsenic activation neutron detector

    DOE Patents [OSTI]

    Jacobs, E.L.

    1980-01-28

    A detector of bursts of neutrons from a deuterium-deuteron reaction includes a quantity of arsenic adjacent a gamma detector such as a scintillator and photomultiplier tube. The arsenic is activated by the 2.5-MeV neutrons to release gamma radiation which is detected to give a quantitative representation of detected neutrons.

  5. Detection Efficiency of Asteroid Surveys

    E-Print Network [OSTI]

    Tricarico, Pasquale

    2015-01-01

    A comprehensive characterization of the detection efficiency of nine of the major asteroid surveys which have been active over the past two decades is presented. The detection efficiency is estimated on a nightly basis by comparing the detected asteroids with the complete catalog of known asteroids propagated to the same observing epoch. Results include a nightly estimate of the detection efficiency curves as a function of apparent magnitude and apparent velocity of the asteroids, as well as a cumulative analysis to estimate the overall performance of each survey. The limiting magnitude distribution is estimated for each survey, and it is then modeled as a function of telescope aperture to obtain an estimate over a wide range of apertures.

  6. Initiative for Explosives Detection

    E-Print Network [OSTI]

    of electromagnetic radiation, or to detect with currently fielded technologies. Approaches to improving detectionInitiative for Explosives Detection Highly Concealed Bulk Explosives Detection This focus area emphasizes the detection of explosives or IEDs hidden in vehicles, buildings or various types of containers

  7. A Simple Technique for Islanding Detection with Negligible Nondetection Zone

    E-Print Network [OSTI]

    Kirtley Jr, James L.

    Although active islanding detection techniques have smaller nondetection zones than passive techniques, active methods could degrade the system power quality and are not as simple and easy to implement as passive methods. ...

  8. Portable modular detection system

    DOE Patents [OSTI]

    Brennan, James S. (Rodeo, CA); Singh, Anup (Danville, CA); Throckmorton, Daniel J. (Tracy, CA); Stamps, James F. (Livermore, CA)

    2009-10-13

    Disclosed herein are portable and modular detection devices and systems for detecting electromagnetic radiation, such as fluorescence, from an analyte which comprises at least one optical element removably attached to at least one alignment rail. Also disclosed are modular detection devices and systems having an integrated lock-in amplifier and spatial filter and assay methods using the portable and modular detection devices.

  9. Image Segmentation Methods for Detecting Blood Vessels in Angiography

    E-Print Network [OSTI]

    Chung, Albert C. S.

    Image Segmentation Methods for Detecting Blood Vessels in Angiography Albert C. S. Chung Lo Kwee-assisted detection and segmentation of blood vessels in angiography are crucial for endovascular treat- ments--Segmentation of Blood Vessels, Feature Detection, Statistical Segmentation, Active Contour Model, Angiography I

  10. Rapid Detection of Botnets through Collaborative Networks of Peers

    E-Print Network [OSTI]

    Malan, David J.

    1 Rapid Detection of Botnets through Collaborative Networks of Peers Final Oral Examination David J Microsoft Windows Graphics Rendering Engine EMF File Privilege Escalation Vulnerability 19 April 2007.e., Time before Detection) #12;10 Detection Isn't Easy Zombies' behavior resembles "normal" activity. Spam

  11. Passive Neutron Detection in Ports for Homeland Security Applications 

    E-Print Network [OSTI]

    Pedicini, Eowyn E

    2013-05-07

    for the detection of SNM being carried on small, personal watercraft. Previous work examined the possibility of using active neutron detectors to induce fission in SNM and detect the response. This thesis examines the possibility of detecting SNM using passive 3He...

  12. Advancing Explosives Detection Capabilities: Vapor Detection

    SciTech Connect (OSTI)

    Atkinson, David

    2012-10-15

    A new, PNNL-developed method provides direct, real-time detection of trace amounts of explosives such as RDX, PETN and C-4. The method selectively ionizes a sample before passing the sample through a mass spectrometer to detect explosive vapors. The method could be used at airports to improve aviation security.

  13. Advancing Explosives Detection Capabilities: Vapor Detection

    ScienceCinema (OSTI)

    Atkinson, David

    2014-07-24

    A new, PNNL-developed method provides direct, real-time detection of trace amounts of explosives such as RDX, PETN and C-4. The method selectively ionizes a sample before passing the sample through a mass spectrometer to detect explosive vapors. The method could be used at airports to improve aviation security.

  14. Bridge Detection By Road Detection Jeff Kaufman

    E-Print Network [OSTI]

    Danner, Andrew

    Bridge Detection By Road Detection Jeff Kaufman cbr@sccs.swarthmore.edu 1 Introduction It is useful, with local min- ima: cells from which there is no direction of descent. A common cause of this is bridges. The area over which a bridge passes shows up in the digital elevation as being of a height greater than

  15. Revolution in Detection Affairs

    SciTech Connect (OSTI)

    Stern W.

    2013-11-02

    The detection of nuclear or radioactive materials for homeland or national security purposes is inherently difficult. This is one reason detection efforts must be seen as just one part of an overall nuclear defense strategy which includes, inter alia, material security, detection, interdiction, consequence management and recovery. Nevertheless, one could argue that there has been a revolution in detection affairs in the past several decades as the innovative application of new technology has changed the character and conduct of detection operations. This revolution will likely be most effectively reinforced in the coming decades with the networking of detectors and innovative application of anomaly detection algorithms.

  16. Interior intrusion detection systems

    SciTech Connect (OSTI)

    Rodriguez, J.R.; Matter, J.C. ); Dry, B. )

    1991-10-01

    The purpose of this NUREG is to present technical information that should be useful to NRC licensees in designing interior intrusion detection systems. Interior intrusion sensors are discussed according to their primary application: boundary-penetration detection, volumetric detection, and point protection. Information necessary for implementation of an effective interior intrusion detection system is presented, including principles of operation, performance characteristics and guidelines for design, procurement, installation, testing, and maintenance. A glossary of sensor data terms is included. 36 figs., 6 tabs.

  17. Student Activities Student Activities

    E-Print Network [OSTI]

    with Solar Energy? Activity B How do Atmospheres Produce their Effect Upon Surface Temperatures? Activity C and populations found in developing countries in Asia, Africa and Latin America. Figure 4.3 illustrates the actual and projected growths in global population. 0Topic ,Real World Problem: Culprits of Climate Warming and Cooling

  18. Fast Neutron Detection Evaluation

    SciTech Connect (OSTI)

    McKigney, Edward A.; Stange, Sy

    2014-03-17

    These slides present a summary of previous work, conclusions, and anticipated schedule for the conclusion of our fast neutron detection evaluation.

  19. Research Article Neural Signals for the Detection

    E-Print Network [OSTI]

    the activation of neural systems designed to detect bias and to recruit controlled processing. Stereotypes of Black people as violent has been implicated in participants' tendency to more quickly identify a weapon for an object thought to be a gun: his wallet. Much research has been focused on elucidating the mechanisms

  20. Ascofuranone suppresses EGF-induced HIF-1? protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells

    SciTech Connect (OSTI)

    Jeong, Yun-Jeong; Cho, Hyun-Ji [Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu 705-718 (Korea, Republic of); Magae, Junji [Magae Bioscience Institute, 49-4 Fujimidai, Tsukuba 300-1263 (Japan); Lee, In-Kyu [Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721 (Korea, Republic of); Park, Keun-Gyu, E-mail: kpark@knu.ac.kr [Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu 700-721 (Korea, Republic of); Chang, Young-Chae, E-mail: ycchang@cu.ac.kr [Research Institute of Biomedical Engineering and Department of Medicine, Catholic University of Daegu School of Medicine, Daegu 705-718 (Korea, Republic of)

    2013-12-15

    Hypoxia-inducible factor (HIF)-1 plays an important role in tumor progression, angiogenesis and metastasis. In this study, we investigated the potential molecular mechanisms underlying the anti-angiogenic effect of ascofuranone, an isoprenoid antibiotic from Ascochyta viciae, in epidermal growth factor (EGF)-1 responsive human breast cancer cells. Ascofuranone significantly and selectively suppressed EGF-induced HIF-1? protein accumulation, whereas it did not affect the expression of HIF-1?. Furthermore, ascofuranone inhibited the transcriptional activation of vascular endothelial growth factor (VEGF) by reducing protein HIF-1?. Mechanistically, we found that the inhibitory effects of ascofuranone on HIF-1? protein expression are associated with the inhibition of synthesis HIF-1? through an EGF-dependent mechanism. In addition, ascofuranone suppressed EGF-induced phosphorylation of Akt/mTOR/p70S6 kinase, but the phosphorylation of ERK/JNK/p38 kinase was not affected by ascofuranone. These results suggest that ascofuranone suppresses EGF-induced HIF-1? protein translation through the inhibition of Akt/mTOR/p70S6 kinase signaling pathways and plays a novel role in the anti-angiogenic action. - Highlights: • Inhibitory effect of ascofuranone on HIF-1? expression is EGF-specific regulation. • Ascofuranone decreases HIF-1? protein synthesis through Akt/mTOR pathways. • Ascofuranone suppresses EGF-induced VEGF production and tumor angiogenesis.

  1. Lean blowoff detection sensor

    DOE Patents [OSTI]

    Thornton, Jimmy (Morgantown, WV); Straub, Douglas L. (Morgantown, WV); Chorpening, Benjamin T. (Morgantown, WV); Huckaby, David (Morgantown, WV)

    2007-04-03

    Apparatus and method for detecting incipient lean blowoff conditions in a lean premixed combustion nozzle of a gas turbine. A sensor near the flame detects the concentration of hydrocarbon ions and/or electrons produced by combustion and the concentration monitored as a function of time are used to indicate incipient lean blowoff conditions.

  2. Array for detecting microbes

    DOE Patents [OSTI]

    Andersen, Gary L.; DeSantis, Todd D.

    2014-07-08

    The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level.

  3. Leak detection aid

    DOE Patents [OSTI]

    Steeper, T.J.

    1989-12-26

    A leak detection apparatus and method for detecting leaks across an O-ring sealing a flanged surface to a mating surface is an improvement in a flanged surface comprising a shallow groove following O-ring in communication with an entrance and exit port intersecting the shallow groove for injecting and withdrawing, respectively, a leak detection fluid, such as helium. A small quantity of helium injected into the entrance port will flow to the shallow groove, past the O-ring and to the exit port. 2 figs.

  4. Leak detection aid

    DOE Patents [OSTI]

    Steeper, Timothy J. (Graniteville, SC)

    1989-01-01

    A leak detection apparatus and method for detecting leaks across an O-ring sealing a flanged surface to a mating surface is an improvement in a flanged surface comprising a shallow groove following O-ring in communication with an entrance and exit port intersecting the shallow groove for injecting and withdrawing, respectively, a leak detection fluid, such as helium. A small quantity of helium injected into the entrance port will flow to the shallow groove, past the O-ring and to the exit port.

  5. Current Trends in Gamma Ray Detection for Radiological Emergency Response

    SciTech Connect (OSTI)

    Mukhopadhyay, S., Guss, P., Maurer, R.

    2011-08-18

    Passive and active detection of gamma rays from shielded radioactive materials, including special nuclear materials, is an important task for any radiological emergency response organization. This article reports on the current trends and status of gamma radiation detection objectives and measurement techniques as applied to nonproliferation and radiological emergencies.

  6. Idaho Explosive Detection System

    ScienceCinema (OSTI)

    Klinger, Jeff

    2013-05-28

    Learn how INL researchers are making the world safer by developing an explosives detection system that can inspect cargo. For more information about INL security research, visit http://www.facebook.com/idahonationallaboratory

  7. Explosive Detection Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2000-10-26

    To standardize and accelerate implementation of the Department of Energy (DOE) explosive detection program. DOE N 251.40, dated 5/3/01, extends this directive until 12/31/01.

  8. Leak testing plan for the Oak Ridge National Laboratory liquid low-level waste systems (active tanks): Revision 2. Volume 1: Regulatory background and plan approach; Volume 2: Methods, protocols, and schedules; Volume 3: Evaluation of the ORNL/LT-823DP differential pressure leak detection method; Appendix to Revision 2: DOE/EPA/TDEC correspondence

    SciTech Connect (OSTI)

    Douglas, D.G.; Wise, R.F.; Starr, J.W.; Maresca, J.W. Jr. [Vista Research, Inc., Mountain View, CA (United States)

    1994-11-01

    This document, the Leak Testing Plan for the Oak Ridge National Laboratory Liquid Low-Level Waste System (Active Tanks), comprises three volumes. The first two volumes address the component-based leak testing plan for the liquid low-level waste system at Oak Ridge, while the third volume describes the performance evaluation of the leak detection method that will be used to test this system. Volume 1, describes that portion of the liquid low-level waste system at that will be tested; it provides the regulatory background, especially in terms of the requirements stipulated in the Federal Facilities Agreement, upon which the leak testing plan is based. Volume 1 also describes the foundation of the plan, portions of which were abstracted from existing federal documents that regulate the petroleum and hazardous chemicals industries. Finally, Volume 1 gives an overview the plan, describing the methods that will be used to test the four classes of components in the liquid low-level waste system. Volume 2 takes the general information on component classes and leak detection methods presented in Volume 1 and shows how it applies particularly to each of the individual components. A complete test plan for each of the components is presented, with emphasis placed on the methods designated for testing tanks. The protocol for testing tank systems is described, and general leak testing schedules are presented. Volume 3 describes the results of a performance evaluation completed for the leak testing method that will be used to test the small tanks at the facility (those less than 3,000 gal in capacity). Some of the details described in Volumes 1 and 2 are expected to change as additional information is obtained, as the viability of candidate release detection methods is proven in the Oak Ridge environment, and as the testing program evolves.

  9. New Detection System for Heavy Element Research

    E-Print Network [OSTI]

    Y. S. Tsyganov; A. N. Polyakov; A. A. Voinov; M. V. Shumeyko

    2015-06-08

    New detection system design for heavy element research with 48Ca projectile has been reported. This system is based on application of 32 position sensitive strip PIPS detector and low pressure pentane filled TOF detector application in 48Ca induced nuclear reactions. To suppress beam associated background products new version of real time method of active correlations has been applied. Examples of applications in 249Bk+48Ca and 243Am+48Ca reactions are presented. The system development to operate together with the digital ORNL detection system to provide a quick search for recoil to alpha correlation chains has been discussed too.

  10. New Detection System for Heavy Element Research

    E-Print Network [OSTI]

    Tsyganov, Y S; Voinov, A A; Shumeyko, M V

    2015-01-01

    New detection system design for heavy element research with 48Ca projectile has been reported. This system is based on application of 32 position sensitive strip PIPS detector and low pressure pentane filled TOF detector application in 48Ca induced nuclear reactions. To suppress beam associated background products new version of real time method of active correlations has been applied. Examples of applications in 249Bk+48Ca and 243Am+48Ca reactions are presented. The system development to operate together with the digital ORNL detection system to provide a quick search for recoil to alpha correlation chains has been discussed too.

  11. Performing Activity Recognition Using an Android Smartphone

    E-Print Network [OSTI]

    Collins, Gary S.

    Performing Activity Recognition Using an Android Smartphone Stefan Dernbach, Barnan Das, Brian-action) activities. The accelerometer in Android phones detects acceleration along three axes dependent upon of acceleration relative to the phone (image retrieved from the android developer website). Activities Simple

  12. Temperature differential detection device

    DOE Patents [OSTI]

    Girling, Peter M. (Allentown, PA)

    1986-01-01

    A temperature differential detection device for detecting the temperature differential between predetermined portions of a container wall is disclosed as comprising a Wheatstone bridge circuit for detecting resistance imbalance with a first circuit branch having a first elongated wire element mounted in thermal contact with a predetermined portion of the container wall, a second circuit branch having a second elongated wire element mounted in thermal contact with a second predetermined portion of a container wall with the wire elements having a predetermined temperature-resistant coefficient, an indicator interconnected between the first and second branches remote from the container wall for detecting and indicating resistance imbalance between the first and second wire elements, and connector leads for electrically connecting the wire elements to the remote indicator in order to maintain the respective resistance value relationship between the first and second wire elements. The indicator is calibrated to indicate the detected resistance imbalance in terms of a temperature differential between the first and second wall portions.

  13. Error detection method

    DOE Patents [OSTI]

    Olson, Eric J.

    2013-06-11

    An apparatus, program product, and method that run an algorithm on a hardware based processor, generate a hardware error as a result of running the algorithm, generate an algorithm output for the algorithm, compare the algorithm output to another output for the algorithm, and detect the hardware error from the comparison. The algorithm is designed to cause the hardware based processor to heat to a degree that increases the likelihood of hardware errors to manifest, and the hardware error is observable in the algorithm output. As such, electronic components may be sufficiently heated and/or sufficiently stressed to create better conditions for generating hardware errors, and the output of the algorithm may be compared at the end of the run to detect a hardware error that occurred anywhere during the run that may otherwise not be detected by traditional methodologies (e.g., due to cooling, insufficient heat and/or stress, etc.).

  14. Composition for detecting uranyl

    DOE Patents [OSTI]

    Baylor, L.C.; Stephens, S.M.

    1994-01-01

    The present invention relates to an indicator composition for use in spectrophotometric detection of a substance in a solution, and a method for making the composition. Useful indicators are sensitive to the particular substance being measured, but are unaffected by the fluid and other chemical species that may be present in the fluid. Optical indicators are used to measure the uranium concentration of process solutions in facilities for extracting uranium from ores, production of nuclear fuels, and reprocessing of irradiated fuels. The composition comprises an organohalide covalently bonded to an indicator for the substance, in such a manner that the product is itself an indicator that provides increased spectral resolution for detecting the substance. The indicator is preferably arsenazo III and the organohalide is preferably cyanuric chloride. These form a composition that is ideally suited for detecting uranyl.

  15. UV Decontamination of MDA Reagents for Single Cell Genomics

    E-Print Network [OSTI]

    Lee, Janey

    2011-01-01

    Reagents for Single Cell Genomics Janey Lee 1* , Damon TigheReagents for Single Cell Genomics Janey Lee 1 , Damon TigheAbstract Single cell genomics, the amplification and

  16. Microsoft Word - 3rd Qtr - MDA.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines light on77 PAGE OF PAGESpersonal information isNoticeRSO March77-29-2005

  17. MDA- Energy Efficiency Revolving Loan Program | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURING OFFICE INDUSTRIALU.S.LeadershipLumileds R&D ImpactsMARVIN S. FERTELMCFC

  18. Relating to ion detection

    DOE Patents [OSTI]

    Orr, Christopher Henry (Calderbridge, GB); Luff, Craig Janson (Calderbridge, GB); Dockray, Thomas (Calderbridge, GB); Macarthur, Duncan Whittemore (Los Alamos, NM)

    2001-01-01

    The apparatus and method provide a technique for improving detection of alpha and/or beta emitting sources on items or in locations using indirect means. The emission forms generate ions in a medium surrounding the item or location and the medium is then moved to a detecting location where the ions are discharged to give a measure of the emission levels. To increase the level of ions generated and render the system particularly applicable for narrow pipes and other forms of conduits, the medium pressure is increased above atmospheric pressure. STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT

  19. Detection of solar events

    DOE Patents [OSTI]

    Fischbach, Ephraim; Jenkins, Jere

    2013-08-27

    A flux detection apparatus can include a radioactive sample having a decay rate capable of changing in response to interaction with a first particle or a field, and a detector associated with the radioactive sample. The detector is responsive to a second particle or radiation formed by decay of the radioactive sample. The rate of decay of the radioactive sample can be correlated to flux of the first particle or the field. Detection of the first particle or the field can provide an early warning for an impending solar event.

  20. Detection of neutrinos

    DOE Patents [OSTI]

    Fischbach, Ephraim; Jenkins, Jere

    2014-02-04

    A flux detection apparatus can include a radioactive sample having a decay rate capable of changing in response to interaction with a first particle or a field, and a detector associated with the radioactive sample. The detector is responsive to a second particle or radiation formed by decay of the radioactive sample. The rate of decay of the radioactive sample can be correlated to flux of the first particle or the field. Detection of the first particle or the field can provide an early warning for an impending solar event.

  1. Detection of counterfeit currency

    DOE Patents [OSTI]

    Burns, D.A.

    1998-05-26

    A method is disclosed of detecting counterfeit currency by contacting the currency to be tested with near infrared beams in the spectrum below 1,250 nanometers, measuring reflectance of the near infrared beams and comparing the reflectance values with those from genuine currency. 18 figs.

  2. HIGH ENERGY POLARIZATION OF BLAZARS: DETECTION PROSPECTS

    SciTech Connect (OSTI)

    Chakraborty, N.; Pavlidou, V.; Fields, B. D.

    2015-01-01

    Emission from blazar jets in the ultraviolet, optical, and infrared is polarized. If these low-energy photons were inverse-Compton scattered, the upscattered high-energy photons retain a fraction of the polarization. Current and future X-ray and gamma-ray polarimeters such as INTEGRAL-SPI, PoGOLITE, X-Calibur, Gamma-Ray Burst Polarimeter, GEMS-like missions, ASTRO-H, and POLARIX have the potential to discover polarized X-rays and gamma-rays from blazar jets for the first time. Detection of such polarization will open a qualitatively new window into high-energy blazar emission; actual measurements of polarization degree and angle will quantitatively test theories of jet emission mechanisms. We examine the detection prospects of blazars by these polarimetry missions using examples of 3C 279, PKS 1510-089, and 3C 454.3, bright sources with relatively high degrees of low-energy polarization. We conclude that while balloon polarimeters will be challenged to detect blazars within reasonable observational times (with X-Calibur offering the most promising prospects), space-based missions should detect the brightest blazars for polarization fractions down to a few percent. Typical flaring activity of blazars could boost the overall number of polarimetric detections by nearly a factor of five to six purely accounting for flux increase of the brightest of the comprehensive, all-sky, Fermi-LAT blazar distribution. The instantaneous increase in the number of detections is approximately a factor of two, assuming a duty cycle of 20% for every source. The detectability of particular blazars may be reduced if variations in the flux and polarization fraction are anticorrelated. Simultaneous use of variability and polarization trends could guide the selection of blazars for high-energy polarimetric observations.

  3. Constituents of political cognition: Race, party politics, and the alliance detection system

    E-Print Network [OSTI]

    Cosmides, Leda

    Constituents of political cognition: Race, party politics, and the alliance detection system David contains a set of adaptations for detecting alliances: an alliance detection system, which monitors for, encodes, and stores alliance information and then modifies the activation of stored alliance categories

  4. Exoplanet Detection Techniques

    E-Print Network [OSTI]

    Fischer, Debra A; Laughlin, Greg P; Macintosh, Bruce; Mahadevan, Suvrath; Sahlmann, Johannes; Yee, Jennifer C

    2015-01-01

    We are still in the early days of exoplanet discovery. Astronomers are beginning to model the atmospheres and interiors of exoplanets and have developed a deeper understanding of processes of planet formation and evolution. However, we have yet to map out the full complexity of multi-planet architectures or to detect Earth analogues around nearby stars. Reaching these ambitious goals will require further improvements in instrumentation and new analysis tools. In this chapter, we provide an overview of five observational techniques that are currently employed in the detection of exoplanets: optical and IR Doppler measurements, transit photometry, direct imaging, microlensing, and astrometry. We provide a basic description of how each of these techniques works and discuss forefront developments that will result in new discoveries. We also highlight the observational limitations and synergies of each method and their connections to future space missions.

  5. Protein detection system

    DOE Patents [OSTI]

    Fruetel, Julie A. (Livermore, CA); Fiechtner, Gregory J. (Bethesda, MD); Kliner, Dahv A. V. (San Ramon, CA); McIlroy, Andrew (Livermore, CA)

    2009-05-05

    The present embodiment describes a miniature, microfluidic, absorption-based sensor to detect proteins at sensitivities comparable to LIF but without the need for tagging. This instrument utilizes fiber-based evanescent-field cavity-ringdown spectroscopy, in combination with faceted prism microchannels. The combination of these techniques will increase the effective absorption path length by a factor of 10.sup.3 to 10.sup.4 (to .about.1-m), thereby providing unprecedented sensitivity using direct absorption. The coupling of high-sensitivity absorption with high-performance microfluidic separation will enable real-time sensing of biological agents in aqueous samples (including aerosol collector fluids) and will provide a general method with spectral fingerprint capability for detecting specific bio-agents.

  6. Chlorofluorocarbon leak detection technology

    SciTech Connect (OSTI)

    Munday, E.B.

    1990-12-01

    There are about 590 large coolant systems located at the Portsmouth Gaseous Diffusion Plant (PORTS) and the Paducah Gaseous Diffusion Plant (PGDP) leaking nearly 800,000 lb of R-114 refrigerant annually (1989 estimate). A program is now under way to reduce the leakage to 325,000 lb/year -- an average loss of 551 lb/year (0.063 lb/h) per coolant system, some of which are as large as 800 ft. This report investigates leak detection technologies that can be used to locate leaks in the coolant systems. Included are descriptions, minimum leak detection rate levels, advantages, disadvantages, and vendor information on the following technologies: bubbling solutions; colorimetric leak testing; dyes; halogen leak detectors (coronea discharge detectors; halide torch detectors, and heated anode detectors); laser imaging; mass spectroscopy; organic vapor analyzers; odorants; pressure decay methods; solid-state electrolytic-cell gas sensors; thermal conductivity leak detectors; and ultrasonic leak detectors.

  7. May Gravity detect Tsunami ?

    E-Print Network [OSTI]

    Fargion, D

    2004-01-01

    The present gravitational wave detectors are reaching lowest metric deviation fields able to detect galactic and extra-galactic gravitational waves, related to Supernova explosions up to Virgo cluster. The same gravitational wave detector are nevertheless almost able to reveal near field gravitational perturbations due to fast huge mass displacements as the ones occurring during largest Earth-Quake or Tsunami as the last on 26th December 2004 in Asiatic area. The prompt gravitational near field deformation by the Tsunami may reach the LIGO threshold sensitivity within 3000-10000 km distances. Their eventual discover (in LIGO data or in future on-line detector arrays) may offer the most rapid warning alarm system on earth. Nevertheless the later continental mass rearrangement and their gravitational field assessment on Earth must induce, for Richter Magnitude 9 Tsunami, a different terrestrial inertia momentum and a different rotation axis, as well as a detectable shrinking of the Earth radius of nearly R =1.7...

  8. Solar neutrino detection

    E-Print Network [OSTI]

    Lino Miramonti

    2009-01-22

    More than 40 years ago, neutrinos where conceived as a way to test the validity of the solar models which tell us that stars are powered by nuclear fusion reactions. The first measurement of the neutrino flux, in 1968 in the Homestake mine in South Dakota, detected only one third of the expected value, originating what has been known as the Solar Neutrino Problem. Different experiments were built in order to understand the origin of this discrepancy. Now we know that neutrinos undergo oscillation phenomenon changing their nature traveling from the core of the Sun to our detectors. In the work the 40 year long saga of the neutrino detection is presented; from the first proposals to test the solar models to last real time measurements of the low energy part of the neutrino spectrum.

  9. Cell Phone Detection Techniques

    SciTech Connect (OSTI)

    Pratt, Richard M.; Bunch, Kyle J.; Puzycki, David J.; Slaugh, Ryan W.; Good, Morris S.; McMakin, Douglas L.

    2007-10-01

    A team composed of Rick Pratt, Dave Puczyki, Kyle Bunch, Ryan Slaugh, Morris Good, and Doug McMakin teamed together to attempt to exploit cellular telephone features and detect if a person was carrying a cellular telephone into a Limited Area. The cell phone’s electromagnetic properties were measured, analyzed, and tested in over 10 different ways to determine if an exploitable signature exists. The method that appears to have the most potential for success without adding an external tag is to measure the RF spectrum, not in the cell phone band, but between 240 and 400MHz. Figures 1- 7 show the detected signal levels from cell phones from three different manufacturers.

  10. Termination Detection of Local Computations

    E-Print Network [OSTI]

    Godard, Emmanuel; Tel, Gerard

    2010-01-01

    Contrary to the sequential world, the processes involved in a distributed system do not necessarily know when a computation is globally finished. This paper investigates the problem of the detection of the termination of local computations. We define four types of termination detection: no detection, detection of the local termination, detection by a distributed observer, detection of the global termination. We give a complete characterisation (except in the local termination detection case where a partial one is given) for each of this termination detection and show that they define a strict hierarchy. These results emphasise the difference between computability of a distributed task and termination detection. Furthermore, these characterisations encompass all standard criteria that are usually formulated : topological restriction (tree, rings, or triangu- lated networks ...), topological knowledge (size, diameter ...), and local knowledge to distinguish nodes (identities, sense of direction). These re- sult...

  11. Method for detecting biomolecules

    DOE Patents [OSTI]

    Huo, Qisheng (Albuquerque, NM); Liu, Jun (Albuquerque, NM)

    2008-08-12

    A method for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode

  12. Fraud Detection in Healthcare

    SciTech Connect (OSTI)

    Chandola, Varun; Schryver, Jack C; Sukumar, Sreenivas R

    2015-01-01

    We discuss the problem of fraud detection in healthcare in this chapter. Given the recent scrutiny of the ineciencies in the US healthcare system, identifying fraud has been on the forefront of the eorts towards reducing the healthcare costs. In this chapter we will focus on understanding the issue of healthcare fraud in detail, and review methods that have been proposed in the literature to combat this issue using data driven approach.

  13. Nucleic acid detection methods

    DOE Patents [OSTI]

    Smith, C.L.; Yaar, R.; Szafranski, P.; Cantor, C.R.

    1998-05-19

    The invention relates to methods for rapidly determining the sequence and/or length a target sequence. The target sequence may be a series of known or unknown repeat sequences which are hybridized to an array of probes. The hybridized array is digested with a single-strand nuclease and free 3{prime}-hydroxyl groups extended with a nucleic acid polymerase. Nuclease cleaved heteroduplexes can be easily distinguish from nuclease uncleaved heteroduplexes by differential labeling. Probes and target can be differentially labeled with detectable labels. Matched target can be detected by cleaving resulting loops from the hybridized target and creating free 3-hydroxyl groups. These groups are recognized and extended by polymerases added into the reaction system which also adds or releases one label into solution. Analysis of the resulting products using either solid phase or solution. These methods can be used to detect characteristic nucleic acid sequences, to determine target sequence and to screen for genetic defects and disorders. Assays can be conducted on solid surfaces allowing for multiple reactions to be conducted in parallel and, if desired, automated. 18 figs.

  14. Nucleic Acid Detection Methods

    DOE Patents [OSTI]

    Smith, Cassandra L. (Boston, MA); Yaar, Ron (Brookline, MA); Szafranski, Przemyslaw (Boston, MA); Cantor, Charles R. (Boston, MA)

    1998-05-19

    The invention relates to methods for rapidly determining the sequence and/or length a target sequence. The target sequence may be a series of known or unknown repeat sequences which are hybridized to an array of probes. The hybridized array is digested with a single-strand nuclease and free 3'-hydroxyl groups extended with a nucleic acid polymerase. Nuclease cleaved heteroduplexes can be easily distinguish from nuclease uncleaved heteroduplexes by differential labeling. Probes and target can be differentially labeled with detectable labels. Matched target can be detected by cleaving resulting loops from the hybridized target and creating free 3-hydroxyl groups. These groups are recognized and extended by polymerases added into the reaction system which also adds or releases one label into solution. Analysis of the resulting products using either solid phase or solution. These methods can be used to detect characteristic nucleic acid sequences, to determine target sequence and to screen for genetic defects and disorders. Assays can be conducted on solid surfaces allowing for multiple reactions to be conducted in parallel and, if desired, automated.

  15. Detection of phenols using engineered bacteria

    DOE Patents [OSTI]

    Wise, Arlene A. (Philadelphia, PA); Kuske, Cheryl R. (Los Alamos, NM); Terwilliger, Thomas C. (Santa Fe, NM)

    2007-12-04

    Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate transcriptional activator senses the inducing chemical. Creation of bacterial biosensors is currently restricted by limited knowledge of the genetic systems of bacteria that catabolize xenobiotics. By using mutagenic PCR to change the chemical specificity of the Pseudomonas species CF600 DmpR protein, the potential for engineering novel biosensors for detection of phenols has been demonstrated. DmpR, a well-characterized transcriptional activator of the P. CF600's dmp operon mediates growth on simple phenols. Transcription from Po, the promoter heading the dmp operon, is activated when the sensor domain of DmpR interacts with phenol and mono-substituted phenols. By altering the sensor domain of the DmpR, a group of DmpR derivatives that activate transcription of a Po-lacZ fusion in response to eight of the EPA's eleven priority pollutant phenols has been created. The assays and the sensor domain mutations that alter the chemical specificity of DmpR is described.

  16. Detection of phenols using engineered bacteria

    DOE Patents [OSTI]

    Wise, Arlene A.; Kuske, Cheryl R.; Terwilliger, Thomas C.

    2004-08-10

    Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate transcriptional activator senses the inducing chemical. Creation of bacterial biosensors is currently restricted by limited knowledge of the genetic systems of bacteria that catabolize xenobiotics. By using mutagenic PCR to change the chemical specificity of the Pseudomonas species CF600 DmpR protein, the potential for engineering novel biosensors for detection of phenols has been demonstrated. DmpR, a well-characterized transcriptional activator of the P. CF600's dmp operon mediates growth on simple phenols. Transcription from Po, the promoter heading the dmp operon, is activated when the sensor domain of DmpR interacts with phenol and mono-substituted phenols. By altering the sensor domain of the DmpR, a group of DmpR derivatives that activate transcription of a Po-lacZ fusion in response to eight of the EPA's eleven priority pollutant phenols has been created. The assays and the sensor domain mutations that alter the chemical specificity of DmpR is described.

  17. A Multidisciplinary Approach To Detect Active Pathways For Magma...

    Open Energy Info (EERE)

    main fissures of the pre-2001 period and that of the 2001 and 2002 lateral eruptions. Soil CO2 and soil temperature surveys carried out in the studied area during the last 3...

  18. Amplified detection of protease activity using porous silicon nanostructures

    E-Print Network [OSTI]

    Orosco, Manuel

    2009-01-01

    Kinetics Initial reaction velocity (V o ) was obtained usingfree solution. Initial reaction velocity (V o ) is typicallyper unit time. The reaction velocity (V o ) is taken as the

  19. A Multidisciplinary Approach To Detect Active Pathways For Magma Migration

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAand Dalton JumpProgram | OpenEnergyEvaluation |Island, Azores | OpenAnd

  20. Methods, microfluidic devices, and systems for detection of an active

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfate Reducing(JournalspectroscopyReport) |(Patent) | SciTechSciTech Connect J.

  1. Methods, microfluidic devices, and systems for detection of an active

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfate Reducing(JournalspectroscopyReport) |(Patent) | SciTechSciTech Connect J.enzymatic agent

  2. Revolution in nuclear detection affairs

    SciTech Connect (OSTI)

    Stern, Warren M.

    2014-05-09

    The detection of nuclear or radioactive materials for homeland or national security purposes is inherently difficult. This is one reason detection efforts must be seen as just one part of an overall nuclear defense strategy which includes, inter alia, material security, detection, interdiction, consequence management and recovery. Nevertheless, one could argue that there has been a revolution in detection affairs in the past several decades as the innovative application of new technology has changed the character and conduct of detection operations. This revolution will likely be most effectively reinforced in the coming decades with the networking of detectors and innovative application of anomaly detection algorithms.

  3. Improved Microseismicity Detection During Newberry EGS Stimulations

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Templeton, Dennise

    2013-11-01

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  4. Improved Microseismicity Detection During Newberry EGS Stimulations

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Templeton, Dennise

    2013-10-01

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  5. Improved Microseismicity Detection During Newberry EGS Stimulations

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Templeton, Dennise

    Effective enhanced geothermal systems (EGS) require optimal fracture networks for efficient heat transfer between hot rock and fluid. Microseismic mapping is a key tool used to infer the subsurface fracture geometry. Traditional earthquake detection and location techniques are often employed to identify microearthquakes in geothermal regions. However, most commonly used algorithms may miss events if the seismic signal of an earthquake is small relative to the background noise level or if a microearthquake occurs within the coda of a larger event. Consequently, we have developed a set of algorithms that provide improved microearthquake detection. Our objective is to investigate the microseismicity at the DOE Newberry EGS site to better image the active regions of the underground fracture network during and immediately after the EGS stimulation. Detection of more microearthquakes during EGS stimulations will allow for better seismic delineation of the active regions of the underground fracture system. This improved knowledge of the reservoir network will improve our understanding of subsurface conditions, and allow improvement of the stimulation strategy that will optimize heat extraction and maximize economic return.

  6. Detecting the climatic effects of increasing carbon dioxide

    SciTech Connect (OSTI)

    MacCracken, M C; Luther, F M [eds.

    1985-12-01

    This report documents what is known about detecting the CO2-induced changes in climate, and describes the uncertainties and unknowns associated with this monitoring and analysis effort. The various approaches for detecting CO2-induced climate changes are discussed first, followed by a review of applications of these strategies to the various climatic variables that are expected to be changing. Recommendations are presented for research and analysis activities. Separate abstracts have been prepared for the individual papers. (ACR)

  7. Flaw detection and evaluation

    DOE Patents [OSTI]

    Wilks, Robert S. (Plum, PA); Sturges, Jr., Robert H. (Plum, PA)

    1983-01-01

    The invention provides a method of and apparatus for optically inspecting nuclear fuel pellets for surface flaws. The inspection system includes a prism and lens arrangement for scanning the surface of each pellet as the same is rotated. The resulting scan produces data indicative of the extent and shape of each flaw which is employed to generate a flaw quality index for each detected flaw. The flaw quality indexes from all flaws are summed and compared with an acceptable surface quality index. The result of the comparison is utilized to control the acceptance or rejection of the pellet.

  8. Opaque cloud detection

    DOE Patents [OSTI]

    Roskovensky, John K. (Albuquerque, NM)

    2009-01-20

    A method of detecting clouds in a digital image comprising, for an area of the digital image, determining a reflectance value in at least three discrete electromagnetic spectrum bands, computing a first ratio of one reflectance value minus another reflectance value and the same two values added together, computing a second ratio of one reflectance value and another reflectance value, choosing one of the reflectance values, and concluding that an opaque cloud exists in the area if the results of each of the two computing steps and the choosing step fall within three corresponding predetermined ranges.

  9. Design of proximity detecting codes 

    E-Print Network [OSTI]

    Perisetty, Srinivas

    1997-01-01

    class of codes called Proximity Detecting Codes can be used to overcome this problem associated with asynchronous channels. A t-proximity detecting (t-PD) code can detect when a received word is within distance t from the transmitted codeword, when using...

  10. Methods and systems for remote detection of gases

    DOE Patents [OSTI]

    Johnson, Timothy J

    2012-09-18

    Novel systems and methods for remotely detecting at least one constituent of a gas via infrared detection are provided. A system includes at least one extended source of broadband infrared radiation and a spectrally sensitive receiver positioned remotely from the source. The source and the receiver are oriented such that a surface of the source is in the field of view of the receiver. The source includes a heating component thermally coupled to the surface, and the heating component is configured to heat the surface to a temperature above ambient temperature. The receiver is operable to collect spectral infrared absorption data representative of a gas present between the source and the receiver. The invention advantageously overcomes significant difficulties associated with active infrared detection techniques known in the art, and provides an infrared detection technique with a much greater sensitivity than passive infrared detection techniques known in the art.

  11. Methods and systems for remote detection of gases

    DOE Patents [OSTI]

    Johnson, Timothy J. (Pasco, WA)

    2007-11-27

    Novel systems and methods for remotely detecting at least one constituent of a gas via infrared detection are provided. A system includes at least one extended source of broadband infrared radiation and a spectrally sensitive receiver positioned remotely from the source. The source and the receiver are oriented such that a surface of the source is in the field of view of the receiver. The source includes a heating component thermally coupled to the surface, and the heating component is configured to heat the surface to a temperature above ambient temperature. The receiver is operable to collect spectral infrared absorption data representative of a gas present between the source and the receiver. The invention advantageously overcomes significant difficulties associated with active infrared detection techniques known in the art, and provides an infrared detection technique with a much greater sensitivity than passive infrared detection techniques known in the art.

  12. Detection of alpha radiation in a beta radiation field

    DOE Patents [OSTI]

    Mohagheghi, Amir H. (Albuquerque, NM); Reese, Robert P. (Edgewood, NM)

    2001-01-01

    An apparatus and method for detecting alpha particles in the presence of high activities of beta particles utilizing an alpha spectrometer. The apparatus of the present invention utilizes a magnetic field applied around the sample in an alpha spectrometer to deflect the beta particles from the sample prior to reaching the detector, thus permitting detection of low concentrations of alpha particles. In the method of the invention, the strength of magnetic field required to adequately deflect the beta particles and permit alpha particle detection is given by an algorithm that controls the field strength as a function of sample beta energy and the distance of the sample to the detector.

  13. Detection and Classification of Buried Metallic Objects UX-1225

    SciTech Connect (OSTI)

    Morrison, Frank; Smith, Torquil; Becker, Alex; Gasperikova, Erika

    2005-03-31

    In summary the technical objectives of this project were: (1) To develop and demonstrate a methodology for the quantitative evaluation of existing active electromagnetic (AEM) systems and for the design of new systems. (2) To implement a new methodology for optimizing an AEM system for detecting and classifying UXO of a given class in a specified geologic setting and in a given noise environment. (3) To design and build a prototype of an active EM system for detecting and characterizing a metallic object in the ground.

  14. Arc fault detection system

    DOE Patents [OSTI]

    Jha, Kamal N. (Bethel Park, PA)

    1999-01-01

    An arc fault detection system for use on ungrounded or high-resistance-grounded power distribution systems is provided which can be retrofitted outside electrical switchboard circuits having limited space constraints. The system includes a differential current relay that senses a current differential between current flowing from secondary windings located in a current transformer coupled to a power supply side of a switchboard, and a total current induced in secondary windings coupled to a load side of the switchboard. When such a current differential is experienced, a current travels through a operating coil of the differential current relay, which in turn opens an upstream circuit breaker located between the switchboard and a power supply to remove the supply of power to the switchboard.

  15. Detection of gas leakage

    DOE Patents [OSTI]

    Thornberg, Steven (Peralta, NM); Brown, Jason (Albuquerque, NM)

    2012-06-19

    A method of detecting leaks and measuring volumes as well as an apparatus, the Power-free Pump Module (PPM), that is a self-contained leak test and volume measurement apparatus that requires no external sources of electrical power during leak testing or volume measurement, where the invention is a portable, pneumatically-controlled instrument capable of generating a vacuum, calibrating volumes, and performing quantitative leak tests on a closed test system or device, all without the use of alternating current (AC) power. Capabilities include the ability is to provide a modest vacuum (less than 10 Torr), perform a pressure rise leak test, measure the gas's absolute pressure, and perform volume measurements. All operations are performed through a simple rotary control valve which controls pneumatically-operated manifold valves.

  16. Digital quadrature phase detection

    DOE Patents [OSTI]

    Smith, James A. (Idaho Falls, ID); Johnson, John A. (Idaho Falls, ID)

    1992-01-01

    A system for detecting the phase of a frequency of phase modulated signal that includes digital quadrature sampling of the frequency or phase modulated signal at two times that are one quarter of a cycle of a reference signal apart, determination of the arctangent of the ratio of a first sampling of the frequency or phase modulated signal to the second sampling of the frequency or phase modulated signal, and a determination of quadrant in which the phase determination is increased by 2.pi. when the quadrant changes from the first quadrant to the fourth quadrant and decreased by 2.pi. when the quadrant changes from the fourth quadrant to the first quadrant whereby the absolute phase of the frequency or phase modulated signal can be determined using an arbitrary reference convention.

  17. Digital quadrature phase detection

    DOE Patents [OSTI]

    Smith, J.A.; Johnson, J.A.

    1992-05-26

    A system for detecting the phase of a frequency or phase modulated signal that includes digital quadrature sampling of the frequency or phase modulated signal at two times that are one quarter of a cycle of a reference signal apart, determination of the arctangent of the ratio of a first sampling of the frequency or phase modulated signal to the second sampling of the frequency or phase modulated signal, and a determination of quadrant in which the phase determination is increased by 2[pi] when the quadrant changes from the first quadrant to the fourth quadrant and decreased by 2[pi] when the quadrant changes from the fourth quadrant to the first quadrant whereby the absolute phase of the frequency or phase modulated signal can be determined using an arbitrary reference convention. 6 figs.

  18. Target detection portal

    DOE Patents [OSTI]

    Linker, Kevin L. (Albuquerque, NM); Brusseau, Charles A. (Tijeras, NM)

    2002-01-01

    A portal apparatus for screening persons or objects for the presence of trace amounts of target substances such as explosives, narcotics, radioactive materials, and certain chemical materials. The portal apparatus can have a one-sided exhaust for an exhaust stream, an interior wall configuration with a concave-shape across a horizontal cross-section for each of two facing sides to result in improved airflow and reduced washout relative to a configuration with substantially flat parallel sides; air curtains to reduce washout; ionizing sprays to collect particles bound by static forces, as well as gas jet nozzles to dislodge particles bound by adhesion to the screened person or object. The portal apparatus can be included in a detection system with a preconcentrator and a detector.

  19. Weld failure detection

    DOE Patents [OSTI]

    Pennell, William E. (Unity Township, Westmoreland County, PA); Sutton, Jr., Harry G. (Mt. Lebanon, PA)

    1981-01-01

    Method and apparatus for detecting failure in a welded connection, particrly applicable to not readily accessible welds such as those joining components within the reactor vessel of a nuclear reactor system. A preselected tag gas is sealed within a chamber which extends through selected portions of the base metal and weld deposit. In the event of a failure, such as development of a crack extending from the chamber to an outer surface, the tag gas is released. The environment about the welded area is directed to an analyzer which, in the event of presence of the tag gas, evidences the failure. A trigger gas can be included with the tag gas to actuate the analyzer.

  20. Waveguide disturbance detection method

    DOE Patents [OSTI]

    Korneev, Valeri A. (Albany, CA); Nihei, Kurt T. (Oakland, CA); Myer, Larry R. (Benicia, CA)

    2000-01-01

    A method for detection of a disturbance in a waveguide comprising transmitting a wavefield having symmetric and antisymmetric components from a horizontally and/or vertically polarized source and/or pressure source disposed symmetrically with respect to the longitudinal central axis of the waveguide at one end of the waveguide, recording the horizontal and/or vertical component or a pressure of the wavefield with a vertical array of receivers disposed at the opposite end of the waveguide, separating the wavenumber transform of the wavefield into the symmetric and antisymmetric components, integrating the symmetric and antisymmetric components over a broad frequency range, and comparing the magnitude of the symmetric components and the antisymmetric components to an expected magnitude for the symmetric components and the antisymmetric components for a waveguide of uniform thickness and properties thereby determining whether or not a disturbance is present inside the waveguide.

  1. Arc fault detection system

    DOE Patents [OSTI]

    Jha, K.N.

    1999-05-18

    An arc fault detection system for use on ungrounded or high-resistance-grounded power distribution systems is provided which can be retrofitted outside electrical switchboard circuits having limited space constraints. The system includes a differential current relay that senses a current differential between current flowing from secondary windings located in a current transformer coupled to a power supply side of a switchboard, and a total current induced in secondary windings coupled to a load side of the switchboard. When such a current differential is experienced, a current travels through a operating coil of the differential current relay, which in turn opens an upstream circuit breaker located between the switchboard and a power supply to remove the supply of power to the switchboard. 1 fig.

  2. Active Knowledge

    E-Print Network [OSTI]

    Freuder, Eugene C.

    A progress report on the work described in Vision Flashes 33 and 43 on recognition of real objects. Emphasis is on the "active" use of knowledge in directing the flow of visual processing.

  3. Amplification of Xenon NMR and MRI by remote detection

    SciTech Connect (OSTI)

    Moule, Adam J.; Spence, Megan M.; Han, Song-I.; Seeley, JulietteA.; Pierce, Kimberly L.; Saxena, Sunil; Pines, Alexander

    2003-03-31

    A novel technique is proposed in which a nuclear magneticresonance (NMR) spectrum or magnetic resonance image (MRI) is encoded andstored as spin polarization and is then moved to a different physicallocation to be detected. Remote detection allows the separateoptimization of the encoding and detection steps, permitting theindependent choice of experimental conditions, and excitation anddetection methodologies. In the first experimental demonstration of thistechnique, we show that NMR signal can be amplified by taking diluted129Xe from a porous sample placed inside a large encoding coil, andconcentrating it into a smaller detection coil. In general, the study ofNMR active molecules at low concentration that have low physical fillingfactor is facilitated by remote detection. In the second experiment, MRIinformation encoded in a very low field magnet (4-7mT) is transferred toa high field magnet (4.2 T) in order to be detected under optimizedconditions. Furthermore, remote detection allows the utilization ofultra-sensitive optical or superconducting detection techniques, whichbroadens the horizon of NMR experimentation.

  4. Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer

    SciTech Connect (OSTI)

    Purcell, James W; Davis, Jefferson; Reddy, Mamatha; Martin, Shamra; Samayoa, Kimberly; Vo, Hung; Thomsen, Karen; Bean, Peter; Kuo, Wen Lin; Ziyad, Safiyyah; Billig, Jessica; Feiler, Heidi S; Gray, Joe W; Wood, Kenneth W; Cases, Sylvaine

    2009-06-10

    Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein (KSP), a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis. Clinical studies of ispinesib have demonstrated a 9% response rate in patients with locally advanced or metastatic breast cancer, and a favorable safety profile without significant neurotoxicities, gastrointestinal toxicities or hair loss. To better understand the potential of ispinesib in the treatment of breast cancer we explored the activity of ispinesib alone and in combination several therapies approved for the treatment of breast cancer. We measured the ispinesib sensitivity and pharmacodynamic response of breast cancer cell lines representative of various subtypes in vitro and as xenografts in vivo, and tested the ability of ispinesib to enhance the anti-tumor activity of approved therapies. In vitro, ispinesib displayed broad anti-proliferative activity against a panel of 53 breast cell-lines. In vivo, ispinesib produced regressions in each of five breast cancer models, and tumor free survivors in three of these models. The effects of ispinesib treatment on pharmacodynamic markers of mitosis and apoptosis were examined in vitro and in vivo, revealing a greater increase in both mitotic and apoptotic markers in the MDA-MB-468 model than in the less sensitive BT-474 model. In vivo, ispinesib enhanced the anti-tumor activity of trastuzumab, lapatinib, doxorubicin, and capecitabine, and exhibited activity comparable to paclitaxel and ixabepilone. These findings support further clinical exploration of KSP inhibitors for the treatment of breast cancer.

  5. Documenting Western Burrowing Owl Reproduction and Activity Patterns Using Motion-Activated Cameras

    SciTech Connect (OSTI)

    Hall, Derek B. [NSTec; Greger, Paul D. [NSTec

    2014-08-01

    We used motion-activated cameras to monitor the reproduction and patterns of activity of the Burrowing Owl (Athene cunicularia) above ground at 45 burrows in south-central Nevada during the breeding seasons of 1999, 2000, 2001, and 2005. The 37 broods, encompassing 180 young, raised over the four years represented an average of 4.9 young per successful breeding pair. Young and adult owls were detected at the burrow entrance at all times of the day and night, but adults were detected more frequently during afternoon/early evening than were young. Motion-activated cameras require less effort to implement than other techniques. Limitations include photographing only a small percentage of owl activity at the burrow; not detecting the actual number of eggs, young, or number fledged; and not being able to track individual owls over time. Further work is also necessary to compare the accuracy of productivity estimates generated from motion-activated cameras with other techniques.

  6. Method for detecting an element

    DOE Patents [OSTI]

    Blackwood, Larry G.; Reber, Edward L.; Rohde, Kenneth W.

    2007-02-06

    A method for detecting an element is disclosed and which includes the steps of providing a gamma-ray spectrum which depicts, at least in part, a test region having boundaries, and which has a small amount of the element to be detected; providing a calculation which detects the small amount of the element to be detected; and providing a moving window and performing the calculation within the moving window, and over a range of possible window boundaries within the test region to determine the location of the optimal test region within the gamma-ray spectrum.

  7. Incipient fire detection system

    DOE Patents [OSTI]

    Brooks, Jr., William K. (Newport News, VA)

    1999-01-01

    A method and apparatus for an incipient fire detection system that receives gaseous samples and measures the light absorption spectrum of the mixture of gases evolving from heated combustibles includes a detector for receiving gaseous samples and subjecting the samples to spectroscopy and determining wavelengths of absorption of the gaseous samples. The wavelengths of absorption of the gaseous samples are compared to predetermined absorption wavelengths. A warning signal is generated whenever the wavelengths of absorption of the gaseous samples correspond to the predetermined absorption wavelengths. The method includes receiving gaseous samples, subjecting the samples to light spectroscopy, determining wavelengths of absorption of the gaseous samples, comparing the wavelengths of absorption of the gaseous samples to predetermined absorption wavelengths and generating a warning signal whenever the wavelengths of absorption of the gaseous samples correspond to the predetermined absorption wavelengths. In an alternate embodiment, the apparatus includes a series of channels fluidically connected to a plurality of remote locations. A pump is connected to the channels for drawing gaseous samples into the channels. A detector is connected to the channels for receiving the drawn gaseous samples and subjecting the samples to spectroscopy. The wavelengths of absorption are determined and compared to predetermined absorption wavelengths is provided. A warning signal is generated whenever the wavelengths correspond.

  8. May Gravity detect Tsunami ?

    E-Print Network [OSTI]

    D. Fargion

    2005-11-23

    The present gravitational wave detectors are reaching lowest metric deviation fields able to detect galactic and extra-galactic gravitational waves, related to Supernova explosions up to Virgo cluster. The same gravitational wave detector are nevertheless almost able to reveal, in principle, near field Newtonian gravitational perturbations due to fast huge mass displacements as the ones occurring during largest Earth-Quake or Tsunami as the last on 26nd December 2004 in Asiatic area. Virgo and Ligo detector are unfortunately recording on high frequencies (above tens Hz) while the signal of the Tsunami lay at much lower range (below 0.1 Hz). Nevertheless prompt gravitational near field deformation by the Tsunami might reach the future LISA threshold sensitivity and frequency windows if such an array is located nearby (3000-10000) km distances. Unfortunately the present LISA system should be located at Lagrange point too far (1.5 million km. far away). We note however that the later continental mass rearrangement and their gravitational field assessment on Earth must induce, for Richter Magnitude 9-like Tsunami, a different terrestrial inertia momentum and a different principal rotation axis. In conclusion we remind that gravitational geodetic deviation on new precise satellites (GOCE 2006), assisted by GPS network, might nevertheless reach in the near future the needed threshold and accuracy to reveal Tsunami by their prompt tidal gravity field deviations . An array of such geoid detector maybe correlated with LISA-like satellite on Earth orbits may offer the fastest alarm system.

  9. Outlier Detection Rules for Fault Detection in Solar Photovoltaic Arrays

    E-Print Network [OSTI]

    Lehman, Brad

    . The models must be modified due to different PV capacity, solar cell technology, or installation locationOutlier Detection Rules for Fault Detection in Solar Photovoltaic Arrays Ye Zhao, Brad Lehman Abstract-- Solar photovoltaic (PV) arrays are unique power sources that may have uncleared fault current

  10. Identifying Activity

    E-Print Network [OSTI]

    Lewis, Adrian S

    2009-01-01

    Identification of active constraints in constrained optimization is of interest from both practical and theoretical viewpoints, as it holds the promise of reducing an inequality-constrained problem to an equality-constrained problem, in a neighborhood of a solution. We study this issue in the more general setting of composite nonsmooth minimization, in which the objective is a composition of a smooth vector function c with a lower semicontinuous function h, typically nonsmooth but structured. In this setting, the graph of the generalized gradient of h can often be decomposed into a union (nondisjoint) of simpler subsets. "Identification" amounts to deciding which subsets of the graph are "active" in the criticality conditions at a given solution. We give conditions under which any convergent sequence of approximate critical points finitely identifies the activity. Prominent among these properties is a condition akin to the Mangasarian-Fromovitz constraint qualification, which ensures boundedness of the set of...

  11. MPI Runtime Error Detection with MUST: Advances in Deadlock Detection

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hilbrich, Tobias; Protze, Joachim; Schulz, Martin; de Supinski, Bronis R.; Müller, Matthias S.

    2013-01-01

    The widely used Message Passing Interface (MPI) is complex and rich. As a result, application developers require automated tools to avoid and to detect MPI programming errors. We present the Marmot Umpire Scalable Tool (MUST) that detects such errors with significantly increased scalability. We present improvements to our graph-based deadlock detection approach for MPI, which cover future MPI extensions. Our enhancements also check complex MPI constructs that no previous graph-based detection approach handled correctly. Finally, we present optimizations for the processing of MPI operations that reduce runtime deadlock detection overheads. Existing approaches often require (p) analysis time per MPI operation,more »forpprocesses. We empirically observe that our improvements lead to sub-linear or better analysis time per operation for a wide range of real world applications.« less

  12. Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and ?-catenin signaling pathway

    SciTech Connect (OSTI)

    Li, Hongzhong; Huang, Jing; Yang, Bing; Xiang, Tingxiu; Yin, Xuedong; Peng, Weiyan; Cheng, Wei; Wan, Jingyuan; Luo, Fuling; Li, Hongyuan; Ren, Guosheng

    2013-10-01

    Although mangiferin which is a naturally occurring glucosylxanthone has exhibited promising anticancer activities, the detailed molecular mechanism of mangiferin on cancers still remains enigmatic. In this study, the anticancer activity of mangiferin was evaluated in breast cancer cell line-based in vitro and in vivo models. We showed that mangiferin treatment resulted in decreased cell viability and suppression of metastatic potential in breast cancer cells. Further mechanistic investigation revealed that mangiferin induced decreased matrix metalloproteinase (MMP)-7 and -9, and reversal of epithelial–mesenchymal transition (EMT). Moreover, it was demonstrated that mangiferin significantly inhibited the activation of ?-catenin pathway. Subsequent experiments showed that inhibiting ?-catenin pathway might play a central role in mangiferin-induced anticancer activity through modulation of MMP-7 and -9, and EMT. Consistent with these findings in vitro, the antitumor potential was also verified in mangiferin-treated MDA-MB-231 xenograft mice where significantly decreased tumor volume, weight and proliferation, and increased apoptosis were obtained, with lower expression of MMP-7 and -9, vimentin and active ?-catenin, and higher expression of E-cadherin. Taken together, our study suggests that mangiferin might be used as an effective chemopreventive agent against breast cancer. - Highlights: • Mangiferin inhibits growth and metastatic potential in breast cancer cells. • Mangiferin down-regulates MMP-7 and -9 in breast cancer cells. • Mangiferin induces the reversal of EMT in metastatic breast cancer cells. • Mangiferin inhibits the activation of ?-catenin pathway in breast cancer cells. • Inhibiting ?-catenin is responsible for the antitumor activity of mangiferin.

  13. Intrusion Detection, Diagnosis, and Recovery with SelfSecuring Storage

    E-Print Network [OSTI]

    Intrusion Detection, Diagnosis, and Recovery with Self­Securing Storage John Strunk, Garth Goodson Carnegie Mellon University Pittsburgh, 15213 Abstract Self­securing storage turns storage devices active parts of intrusion survival strategy. From behind storage interface (e.g., SCSI CIFS), a self

  14. Analysis and Application of Node Layout Algorithms for Intrusion Detection

    E-Print Network [OSTI]

    Erbacher, Robert F.

    monitoring environment aids system administrators in keeping track of the activities on such systems for complete analysis and monitoring of the environment. Developing an effective organization of the nodes or inconsequential. Our intrusion detection monitoring environment [6, 7] is geared towards aiding in this analysis

  15. Efficient Coverage Maintenance Based on Probabilistic Distributed Detection

    E-Print Network [OSTI]

    Lu, Chenyang

    sufficient sensing coverage over long periods of time. To conserve energy, a coverage maintenance protocol.e., probabilistic detection by individual sensors and data fusion among sensors. We then present three coverage fusion groups, but increases the number of active sensors due to the lack of collaboration among sensors

  16. Rapid Detection of Maintenance Induced Changes in Service Performance

    E-Print Network [OSTI]

    Greenberg, Albert

    - plicated interactions across devices or software. During a maintenance activity, the Operations team is reRapid Detection of Maintenance Induced Changes in Service Performance Ajay Mahimkar , Zihui Ge ­ Research AT&T, Inc. The University of Texas at Austin § ABSTRACT Service quality in operational IP

  17. SENSING THE ENVIRONMENT Detection and Generation of Electric Signals

    E-Print Network [OSTI]

    be actively generated by an electric organ or passively generated due to the uneven distribution of ions of kilohertz such as those produced by an EOD. Electrosense The ability to detect electric fields. A passive to a unique form of electricity ­ an innate vital force housed within animal tissue that was released

  18. Detection of nucleic acids by multiple sequential invasive cleavages

    DOE Patents [OSTI]

    Hall, Jeff G; Lyamichev, Victor I; Mast, Andrea L; Brow, Mary Ann D

    2012-10-16

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of human cytomegalovirus nucleic acid in a sample.

  19. Activity report

    SciTech Connect (OSTI)

    Yu, S W

    2008-08-11

    This report is aimed to show the author's activities to support the LDRD. The title is 'Investigation of the Double-C Behavior in the Pu-Ga Time-Temperature-Transformation Diagram' The sections are: (1) Sample Holder Test; (2) Calculation of x-ray diffraction patterns; (3) Literature search and preparing publications; (4) Tasks Required for APS Experiments; and (5) Communications.

  20. Supernova Neutrinos Detection On Earth

    E-Print Network [OSTI]

    Xin-Heng Guo; Ming-Yang Huang; Bing-Lin Young

    2009-05-12

    In this paper, we first discuss the detection of supernova neutrino on Earth. Then we propose a possible method to acquire information about $\\theta_{13}$ smaller than $1.5^\\circ$ by detecting the ratio of the event numbers of different flavor supernova neutrinos. Such an sensitivity cannot yet be achieved by the Daya Bay reactor neutrino experiment.

  1. Neutron Detection Efficiency of the

    E-Print Network [OSTI]

    Gilfoyle, Jerry

    Neutron Detection Efficiency of the CLAS12 Detector M. Moog and G. Gilfoyle University Of Richmond - Department of Physics Software We simulated the neutron detection efficiency of the forward time of flight scintillators for quasielastic electron-neutron scattering using a series of software packages. Elastic

  2. Particle detection systems and methods

    DOE Patents [OSTI]

    Morris, Christopher L.; Makela, Mark F.

    2010-05-11

    Techniques, apparatus and systems for detecting particles such as muons and neutrons. In one implementation, a particle detection system employs a plurality of drift cells, which can be for example sealed gas-filled drift tubes, arranged on sides of a volume to be scanned to track incoming and outgoing charged particles, such as cosmic ray-produced muons. The drift cells can include a neutron sensitive medium to enable concurrent counting of neutrons. The system can selectively detect devices or materials, such as iron, lead, gold, uranium, plutonium, and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can concurrently detect any unshielded neutron sources occupying the volume from neutrons emitted therefrom. If necessary, the drift cells can be used to also detect gamma rays. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.

  3. Estimation of iron-55 volumetric contamination via surrogates produced during Z-machine operations 

    E-Print Network [OSTI]

    Flores-McLaughlin, John

    2009-05-15

    to the National Science Foundation Bridge to the Doctorate program which provided the primary funding and scholarly discussions towards this academic pursuit. vi NOMENCLATURE MDA Minimum Detectable Activity Fe Iron Cr Chromium Co Cobalt............................................................................................................................. 34 viii LIST OF FIGURES FIGURE Page 1 Cr-50 (n, ?) Cr-51 and Fe-54 (n, ?) Fe-55 probability vs. incident neutron...

  4. Bubble Radiation Detection: Current and Future Capability

    SciTech Connect (OSTI)

    AJ Peurrung; RA Craig

    1999-11-15

    Despite a number of noteworthy achievements in other fields, superheated droplet detectors (SDDs) and bubble chambers (BCs) have not been used for nuclear nonproliferation and arms control. This report examines these two radiation-detection technologies in detail and answers the question of how they can be or should be ''adapted'' for use in national security applications. These technologies involve closely related approaches to radiation detection in which an energetic charged particle deposits sufficient energy to initiate the process of bubble nucleation in a superheated fluid. These detectors offer complete gamma-ray insensitivity when used to detect neutrons. They also provide controllable neutron-energy thresholds and excellent position resolution. SDDs are extraordinarily simple and inexpensive. BCs offer the promise of very high efficiency ({approximately}75%). A notable drawback for both technologies is temperature sensitivity. As a result of this problem, the temperature must be controlled whenever high accuracy is required, or harsh environmental conditions are encountered. The primary findings of this work are listed and briefly summarized below: (1) SDDs are ready to function as electronics-free neutron detectors on demand for arms-control applications. The elimination of electronics at the weapon's location greatly eases the negotiability of radiation-detection technologies in general. (2) As a result of their high efficiency and sharp energy threshold, current BCs are almost ready for use in the development of a next-generation active assay system. Development of an instrument based on appropriately safe materials is warranted. (3) Both kinds of bubble detectors are ready for use whenever very high gamma-ray fields must be confronted. Spent fuel MPC and A is a good example where this need presents itself. (4) Both kinds of bubble detectors have the potential to function as low-cost replacements for conventional neutron detectors such as {sup 3}He tubes. For SDDs, this requires finding some way to get boron into the detector. For BCs, this requires finding operating conditions permitting a high duty cycle.

  5. Method and apparatus for enhanced detection of toxic agents

    DOE Patents [OSTI]

    Greenbaum, Elias (Knoxville, TN); Rodriguez, Jr., Miguel (Oak Ridge, TN); Wu, Jie Jayne (Knoxville, TN); Qi, Hairong (Knoxville, TN)

    2012-06-12

    A water quality analyzer for real-time detection according to the invention comprises a biased AC electro-osmosis (ACEO) cell for receiving a fluid to be analyzed having a plurality photosynthetic organisms therein, and concentrating the plurality photosynthetic organisms into at least one concentrated region. A photodetector is provided for obtaining a measured photosynthetic activity of the plurality of photosynthetic organisms in the concentrated region, wherein chemical, biological or radiological agents reduce a nominal photosynthetic activity of the photosynthetic organisms. An electronics package analyzes the measured photosynthetic activity to indicate a presence of the chemical, biological or radiological agents in the fluid.

  6. Laboratory Activities

    SciTech Connect (OSTI)

    Brown, Christopher F.; Serne, R. Jeffrey

    2008-01-17

    This chapter summarizes the laboratory activities performed by PNNL’s Vadose Zone Characterization Project in support of the Tank Farm Vadose Zone Program, led by CH2M HILL Hanford Group, Inc. The results of these studies are contained in numerous reports (Lindenmeier et al. 2002; Serne et al. 2002a, 2002b, 2002c, 2002d, 2002e; Lindenmeier et al. 2003; Serne et al. 2004a, 2004b; Brown et al. 2005, 2006a, 2007; Serne et al. 2007) and have generated much of the data reported in Chapter 22 (Geochemistry-Contaminant Movement), Appendix G (Geochemistry-Contaminant Movement), and Cantrell et al. (2007, SST WMA Geochemistry Data Package – in preparation). Sediment samples and characterization results from PNNL’s Vadose Zone Characterization Project are also shared with other science and technology (S&T) research projects, such as those summarized in Chapter 12 (Associated Science Activities).

  7. Direct In Vivo Electrochemical Detection of Haemoglobin in Red Blood Cells

    E-Print Network [OSTI]

    Toh, Rou Jun

    The electrochemical behavior of iron ion in haemoglobin provides insight to the chemical activity in the red blood cell which is important in the field of hematology. Herein, the detection of haemoglobin in human red blood ...

  8. Specific expression of the human voltage-gated proton channel Hv1 in highly metastatic breast cancer cells, promotes tumor progression and metastasis

    SciTech Connect (OSTI)

    Wang, Yifan [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China)] [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China); Li, Shu Jie, E-mail: shujieli@nankai.edu.cn [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China); Pan, Juncheng [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China)] [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China); Che, Yongzhe, E-mail: cheli@nankai.edu.cn [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Medicine, Nankai University, Tianjin 300071 (China)] [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Medicine, Nankai University, Tianjin 300071 (China); Yin, Jian [Cancer Institute and Hospital, Tianjin Medical University, Tianjin 300060 (China)] [Cancer Institute and Hospital, Tianjin Medical University, Tianjin 300060 (China); Zhao, Qing [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China)] [The Key Laboratory of Bioactive Materials, Ministry of Education, School of Physics Science, Nankai University, Tianjin 300071 (China)

    2011-08-26

    Highlights: {yields} Hv1 is specifically expressed in highly metastatic human breast tumor tissues. {yields} Hv1 regulates breast cancer cytosolic pH. {yields} Hv1 acidifies extracellular milieu. {yields} Hv1 exacerbates the migratory ability of metastatic cells. -- Abstract: The newly discovered human voltage-gated proton channel Hv1 is essential for proton transfer, which contains a voltage sensor domain (VSD) without a pore domain. We report here for the first time that Hv1 is specifically expressed in the highly metastatic human breast tumor tissues, but not in poorly metastatic breast cancer tissues, detected by immunohistochemistry. Meanwhile, real-time RT-PCR and immunocytochemistry showed that the expression levels of Hv1 have significant differences among breast cancer cell lines, MCF-7, MDA-MB-231, MDA-MB-468, MDA-MB-453, T-47D and SK-BR-3, in which Hv1 is expressed at a high level in highly metastatic human breast cancer cell line MDA-MB-231, but at a very low level in poorly metastatic human breast cancer cell line MCF-7. Inhibition of Hv1 expression in the highly metastatic MDA-MB-231 cells by small interfering RNA (siRNA) significantly decreases the invasion and migration of the cells. The intracellular pH of MDA-MB-231 cells down-regulated Hv1 expression by siRNA is obviously decreased compared with MDA-MB-231 with the scrambled siRNA. The expression of matrix metalloproteinase-2 and gelatinase activity in MDA-MB-231 cells suppressed Hv1 by siRNA were reduced. Our results strongly suggest that Hv1 regulates breast cancer intracellular pH and exacerbates the migratory ability of metastatic cells.

  9. QueueTrak: Automated Line Length Detection using a Wireless Sensor Network

    E-Print Network [OSTI]

    Whitehouse, Kamin

    , it uses a series of custom active infrared sensors to detect the length of a line in a store or restaurant the design, implementation, and evaluation of QueueTrak, a sensor network that measures the length of linesQueueTrak: Automated Line Length Detection using a Wireless Sensor Network Jared Alexander, Matthew

  10. Automatic detection of atrial fibrillation using the coefficient of variation and

    E-Print Network [OSTI]

    Glass, Leon

    f Automatic detection of atrial fibrillation using the coefficient of variation and density, Quebec, Canada \\ Abstract--The paper describes a method for the automatic detection of atria, as P-waves are difficult to determine automatically, and irregular baseline activity of the ECG

  11. Trace Explosive Detection Using Nanosensors

    SciTech Connect (OSTI)

    Senesac, Larry R [ORNL; Thundat, Thomas George [ORNL

    2008-01-01

    Selective and sensitive detection of explosives is very important in countering terrorist threats. Detecting trace explosives has become a very complex and expensive endeavor because of a number of factors, such as the wide variety of materials that can be used as explosives, the lack of easily detectable signatures, the vast number of avenues by which these weapons can be deployed, and the lack of inexpensive sensors with high sensitivity and selectivity. High sensitivity and selectivity, combined with the ability to lower the deployment cost of sensors using mass production, is essential in winning the war on explosives-based terrorism. Nanosensors have the potential to satisfy all the requirements for an effective platform for the trace detection of explosives.

  12. Track detection: an MCM approach 

    E-Print Network [OSTI]

    Kotha, Kedarnath S.

    1993-01-01

    132ns. A new integrated circuit packaging structure coupled with a purely hardware system was needed to meet the high speed and best performance requirements for track detection of subatomic particles. Microprocessors cannot be used for this kind...

  13. Parametric Feature Detection CUCS02895

    E-Print Network [OSTI]

    , efficient search, feature detection, parameter estimation, step edges, roof edges, corners, lines, discs. The concepts of parameter reduction by normalization, dimension reduction, pattern rejection, and efficient search are employed to achieve high efficiency. Detectors have been implemented for five specific

  14. Active pixel sensors for X-ray astronomy

    E-Print Network [OSTI]

    Cohen, Matthew (Matthew L.)

    2005-01-01

    An active pixel sensor array, APS-1, has been fabricated for the purpose of scientific x-ray detection. This thesis presents the results of testing the device. Alternate design architectures are explored. Recommendations ...

  15. Simultaneous Detection and Registration for Ileo-Cecal Valve Detection in 3D CT Colonography

    E-Print Network [OSTI]

    Barbu, Adrian

    Simultaneous Detection and Registration for Ileo-Cecal Valve Detection in 3D CT Colonography Le Lu1-Cecal Valve (ICV) detection in both clean and tagged 3D CT colonography scans. Our final ICV detection system

  16. System for detecting special nuclear materials

    SciTech Connect (OSTI)

    Jandel, Marian; Rusev, Gencho Yordanov; Taddeucci, Terry Nicholas

    2015-07-14

    The present disclosure includes a radiological material detector having a convertor material that emits one or more photons in response to a capture of a neutron emitted by a radiological material; a photon detector arranged around the convertor material and that produces an electrical signal in response to a receipt of a photon; and a processor connected to the photon detector, the processor configured to determine the presence of a radiological material in response to a predetermined signature of the electrical signal produced at the photon detector. One or more detectors described herein can be integrated into a detection system that is suited for use in port monitoring, treaty compliance, and radiological material management activities.

  17. Detecting fission from special nuclear material sources

    DOE Patents [OSTI]

    Rowland, Mark S. (Alamo, CA); Snyderman, Neal J. (Berkeley, CA)

    2012-06-05

    A neutron detector system for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly into information that a first responder can use to discriminate materials. The system comprises counting neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source. The system includes a graphing component that displays the plot of the neutron distribution from the unknown source over a Poisson distribution and a plot of neutrons due to background or environmental sources. The system further includes a known neutron source placed in proximity to the unknown source to actively interrogate the unknown source in order to accentuate differences in neutron emission from the unknown source from Poisson distributions and/or environmental sources.

  18. Wise detections of known QSOs at redshifts greater than six

    SciTech Connect (OSTI)

    Blain, Andrew W. [Physics and Astronomy, University of Leicester, 1 University Road, Leicester LE1 7RH (United Kingdom); Assef, Roberto; Stern, Daniel; Tsai, Chao-Wei; Eisenhardt, Peter [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Bridge, Carrie [California Institute of Technology, 249-17, Pasadena, CA 91125 (United States); Benford, Dominic [Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Jarrett, Tom [Astronomy Department, University of Cape Town (South Africa); Cutri, Roc [Infrared Processing and Analysis Center, California Institute of Technology, MS100-22, Pasadena, CA 91125 (United States); Petty, Sara [Virginia Tech, Department of Physics MC 0435, 910 Drillfield Drive, Blacksburg, VA 24061 (United States); Wu, Jingwen; Wright, Edward L., E-mail: ab520@le.ac.uk [Division of Astronomy and Astrophysics, University of California, Los Angeles, Physics and Astronomy Building, 430 Portola Plaza, Los Angeles, CA 90095-1547 (United States)

    2013-12-01

    We present WISE All-Sky mid-infrared (IR) survey detections of 55% (17/31) of the known QSOs at z > 6 from a range of surveys: the SDSS, the CFHT-LS, FIRST, Spitzer, and UKIDSS. The WISE catalog thus provides a substantial increase in the quantity of IR data available for these sources: 17 are detected in the WISE W1 (3.4 ?m) band, 16 in W2 (4.6 ?m), 3 in W3 (12 ?m), and 0 in W4 (22 ?m). This is particularly important with Spitzer in its warm-mission phase and no faint follow-up capability at wavelengths longward of 5 ?m until the launch of James Webb Space Telescope (JWST). WISE thus provides a useful tool for understanding QSOs found in forthcoming large-area optical/IR sky surveys using PanSTARRS, SkyMapper, VISTA, DES, and LSST. The rest-UV properties of the WISE-detected and the WISE-non-detected samples differ: the detections have brighter i/z-band magnitudes and redder rest-UV colors. This suggests that a more aggressive hunt for very high redshift QSOs by combining WISE W1 and W2 data with red, observed optical colors could be effective at least for a subset of dusty candidate QSOs. Stacking the WISE images of the WISE-non-detected QSOs indicates that they are, on average, significantly fainter than the WISE-detected examples, and are thus not narrowly missing detection in the WISE catalog. The WISE catalog detection of three of our sample in the W3 band indicates that their mid-IR flux can be detected individually, although there is no stacked W3 detection of sources detected in W1 but not W3. Stacking analyses of WISE data for large active galactic nucleus samples will be a useful tool, and high-redshift QSOs of all types will be easy targets for JWST.

  19. Radio frequency detection assembly and method for detecting radio frequencies

    DOE Patents [OSTI]

    Cown, Steven H. (Rigby, ID); Derr, Kurt Warren (Idaho Falls, ID)

    2010-03-16

    A radio frequency detection assembly is described and which includes a radio frequency detector which detects a radio frequency emission produced by a radio frequency emitter from a given location which is remote relative to the radio frequency detector; a location assembly electrically coupled with the radio frequency detector and which is operable to estimate the location of the radio frequency emitter from the radio frequency emission which has been received; and a radio frequency transmitter electrically coupled with the radio frequency detector and the location assembly, and which transmits a radio frequency signal which reports the presence of the radio frequency emitter.

  20. Optically Detected Magnetic Resonance Studies on ?-conjugated...

    Office of Scientific and Technical Information (OSTI)

    ThesisDissertation: Optically Detected Magnetic Resonance Studies on -conjugated semiconductor systems Citation Details In-Document Search Title: Optically Detected Magnetic...

  1. Representing the Gaichi in Japanese Detective Fiction

    E-Print Network [OSTI]

    Cruz, Aileen Marie

    2014-01-01

    Shinchosa, 1990. Kawana, Sari. Murder Most Modern: DetectiveDetective Fiction Writer?s Murder” Conclusion Bibliography itheir illicit attachment. The murder-suicide via bomb in “A

  2. Advancing the art of tuberculosis detection

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Advancing art of tuberculosis detection Advancing the art of tuberculosis detection New approach to finding a TB biomarker could provide earlier diagnosis. April 19, 2013 Los...

  3. Review of Current Neutron Detection Systems for Emergency Response

    SciTech Connect (OSTI)

    Mukhopadhyay, S.; Maurer, R.; Guss, P.; Kruschwitz, C.

    2014-09-01

    Neutron detectors are used in a myriad of applications—from safeguarding special nuclear materials (SNM) to determining lattice spacing in soft materials. The transformational changes taking place in neutron detection and imaging techniques in the last few years are largely being driven by the global shortage of helium-3 (3He). This article reviews the status of neutron sensors used specifically for SNM detection in radiological emergency response. These neutron detectors must be highly efficient, be rugged, have fast electronics to measure neutron multiplicity, and be capable of measuring direction of the neutron sources and possibly image them with high spatial resolution. Neutron detection is an indirect physical process: neutrons react with nuclei in materials to initiate the release of one or more charged particles that produce electric signals that can be processed by the detection system. Therefore, neutron detection requires conversion materials as active elements of the detection system; these materials may include boron-10 (10B), lithium-6 (6Li), and gadollinium-157 (157Gd), to name a few, but the number of materials available for neutron detection is limited. However, in recent years, pulse-shape-discriminating plastic scintillators, scintillators made of helium-4 (4He) under high pressure, pillar and trench semiconductor diodes, and exotic semiconductor neutron detectors made from uranium oxide and other materials have widely expanded the parameter space in neutron detection methodology. In this article we will pay special attention to semiconductor-based neutron sensors. Modern micro-fabricated nanotubes covered inside with neutron converter materials and with very high aspect ratios for better charge transport will be discussed.

  4. A BAYESIAN HIERARCHICAL DETECTION FRAMEWORK FOR PARKING SPACE DETECTION

    E-Print Network [OSTI]

    Chen, Tsuhan

    University, Hsinchu, Taiwan. 2 Department of Electrical and Computer Engineering, Carnegie Mellon University problem come from luminance variations, inter- occlusions among cars, and occlusions caused to the parking space detection problem, the available parking spaces and the labeling of parked cars can

  5. Detecting bioterrorism: Is chemistry enough?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalent BondingMeeting |Design CompetitionsFuelof 12Detecting andDetecting

  6. Ultrahigh Energy Cosmic Rays Detection

    E-Print Network [OSTI]

    Carla Aramo

    2005-09-06

    The paper describes methods used for the detection of cosmic rays with energies above 10^18 eV (UHECR, UltraHigh Energy Cosmic Rays). It had been anticipated there would be a cutoff in the energy spectrum of primary cosmic rays around 3 10^19 eV induced by their interaction with the 2.7 K primordial photons. This has become known as the GZK cutoff. However, several showers have been detected with estimated primary energy exceeding this limit.

  7. Bumblebee vibration activated foraging

    E-Print Network [OSTI]

    Su, Dan Kuan-Nien

    2009-01-01

    SAN DIEGO Bumblebee vibration activated foraging: A ThesisOF THE THESIS Bumblebee vibration activated foraging by Danproduce brief bursts of vibration (foraging activation

  8. Towards the detection of magnetohydrodynamics instabilities in a fusion reactor

    SciTech Connect (OSTI)

    Sozzi, Carlo, E-mail: sozzi@ifp.cnr.it; Alessi, E., E-mail: sozzi@ifp.cnr.it; Figini, L., E-mail: sozzi@ifp.cnr.it; Galperti, G., E-mail: sozzi@ifp.cnr.it; Lazzaro, E., E-mail: sozzi@ifp.cnr.it; Marchetto, C., E-mail: sozzi@ifp.cnr.it; Nowak, S. [Istituto di Fisica del Plasma, CNR, EURATOM-ENEA Association, Milano (Italy); Mosconi, M. [Dipartimento di Energia, Politecnico di Milano, Milano (Italy)

    2014-08-21

    Various active control strategies of the Neoclassical tearing modes are being studied in present tokamaks using established detection techniques which exploit the measurements of the fluctuations of the magnetic field and of the electron temperature. The extrapolation of such techniques to the fusion reactor scale is made problematic by the neutron fluence and by the physics conditions related to the high plasma temperature and density which degrade the spatial resolution of such measurements.

  9. Project of the underwater system for chemical threat detection

    E-Print Network [OSTI]

    Silarski, M; Moskal, P; Smolis, M; Tadeja, S

    2015-01-01

    In this article we describe a novel method for the detection of explosives and other hazardous substances in the marine environment using neutron activation. Unlike the other considered methods based on this technique we propose to use guides forneutron and gamma quanta which speeds up and simplifies identification. Moreover, it may provide a determination of the density distribution of a dangerous substance. First preliminary results of Monte Carlo simulations dedicated for design of a device exploiting this method are also presented.

  10. Mechanical approach to the neutrons spectra collimation and detection

    SciTech Connect (OSTI)

    Sadeghi, H.; Roshan, M. V.

    2014-11-15

    Neutrons spectra from most of known sources require being collimated for numerous applications; among them one is the Neutron Activation Analysis. High energy neutrons are collimated through a mechanical procedure as one of the most promising methods. The output energy of the neutron beam depends on the velocity of the rotating Polyethylene disks. The collimated neutrons are then measured by an innovative detection technique with high accuracy.

  11. Noise canceling in-situ detection

    SciTech Connect (OSTI)

    Walsh, David O.

    2014-08-26

    Technologies applicable to noise canceling in-situ NMR detection and imaging are disclosed. An example noise canceling in-situ NMR detection apparatus may comprise one or more of a static magnetic field generator, an alternating magnetic field generator, an in-situ NMR detection device, an auxiliary noise detection device, and a computer.

  12. Distributed Termination Detection for Dynamic Systems

    E-Print Network [OSTI]

    Dhamdhere, Dhananjay Madhav

    systems, Termination detection. \\Lambda Address all correspondence to this author. 1 #12; Distributed

  13. Anomalous change detection in imagery

    DOE Patents [OSTI]

    Theiler, James P. (Los Alamos, NM); Perkins, Simon J. (Santa Fe, NM)

    2011-05-31

    A distribution-based anomaly detection platform is described that identifies a non-flat background that is specified in terms of the distribution of the data. A resampling approach is also disclosed employing scrambled resampling of the original data with one class specified by the data and the other by the explicit distribution, and solving using binary classification.

  14. Electromagnetic Interrogation Techniques Damage Detection

    E-Print Network [OSTI]

    Electromagnetic Interrogation Techniques for Damage Detection H. T. Banks and M. L. Joyner Center.P. Winfree Nasa Langley Research Center Hampton, VA Plenary Lecture, Electromagnetic Nondestructive Evaluation 2001 (ENDE 2001), Kobe, Japan, May 18-19, 20001 #12;Electromagnetic Interrogation Techniques

  15. Electromagnetic Interrogation Techniques Damage Detection

    E-Print Network [OSTI]

    Electromagnetic Interrogation Techniques for Damage Detection H. T. Banks #3; and M. L. Joyner Wincheski and W.P. Winfree Nasa Langley Research Center Hampton, VA #3; Plenary Lecture, Electromagnetic Nondestructive Evaluation 2001 (ENDE 2001), Kobe, Japan, May 18­19, 20001 #12; Electromagnetic Interrogation

  16. Detection of explosives in soils

    DOE Patents [OSTI]

    Chambers, William B. (Edgewood, NM); Rodacy, Philip J. (Albuquerque, NM); Phelan, James M. (Bosque Farms, NM); Woodfin, Ronald L. (Sandia Park, NM)

    2002-01-01

    An apparatus and method for detecting explosive-indicating compounds in subsurface soil. The apparatus has a probe with an adsorbent material on some portion of its surface that can be placed into soil beneath the ground surface, where the adsorbent material can adsorb at least one explosive-indicating compound. The apparatus additional has the capability to desorb the explosive-indicating compound through heating or solvent extraction. A diagnostic instrument attached to the probe detects the desorbed explosive-indicating compound. In the method for detecting explosive-indicating compounds in soil, the sampling probe with an adsorbent material on at least some portion of a surface of the sampling probe is inserted into the soil to contact the adsorbent material with the soil. The explosive-indicating compounds are then desorbed and transferred as either a liquid or gas sample to a diagnostic tool for analysis. The resulting gas or liquid sample is analyzed using at least one diagnostic tool selected from the group consisting of an ion-mobility spectrometer, a gas chromatograph, a high performance liquid chromatograph, a capillary electrophoresis chromatograph, a mass spectrometer, a Fourier-transform infrared spectrometer and a Raman spectrometer to detect the presence of explosive-indicating compounds.

  17. AT NORTHWESTERN EARLY CANCER DETECTION

    E-Print Network [OSTI]

    Chisholm, Rex L.

    --including lung cancer, pancreatic cancer, and ovarian cancer-- there is simply no screening option available, such as pancreatic, ovarian, and lung cancer. · Improve existing screening techniques, such as those for colon cancer, with the THE CANCER INSTITUTES AT NORTHWESTERN MEDICINE EARLY CANCER DETECTION TECHNOLOGIES INSTITUTE

  18. Detect

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HAB Packet HanfordDOEDanielDeSmall Business ForumDesignerFile

  19. detection

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal GasAdministration Medal01 Sandia4)9 Federal RegisterStorm1 3446 YEAR/%2A en Defense9/%2A

  20. Intermediate Energy Infobook Activities (29 Activities)

    K-12 Energy Lesson Plans and Activities Web site (EERE)

    Information about Intermediate Energy Infobook, 29 student activities on energy basics for grades 5-8.

  1. Method for photon activation positron annihilation analysis

    DOE Patents [OSTI]

    Akers, Douglas W.

    2006-06-06

    A non-destructive testing method comprises providing a specimen having at least one positron emitter therein; determining a threshold energy for activating the positron emitter; and determining whether a half-life of the positron emitter is less than a selected half-life. If the half-life of the positron emitter is greater than or equal to the selected half-life, then activating the positron emitter by bombarding the specimen with photons having energies greater than the threshold energy and detecting gamma rays produced by annihilation of positrons in the specimen. If the half-life of the positron emitter is less then the selected half-life, then alternately activating the positron emitter by bombarding the specimen with photons having energies greater then the threshold energy and detecting gamma rays produced by positron annihilation within the specimen.

  2. Poster Abstract: Towards Active Measurements of Edge Network Outages

    E-Print Network [OSTI]

    Heidemann, John

    Poster Abstract: Towards Active Measurements of Edge Network Outages Lin Quan John Heidemann Yuri-to-end reachability is a fundamental service of the Internet. We study net- work outages caused by natural disasters [2,5], and political upheavals [8]. We propose a new approach to outage detection using active

  3. Active Pedestrian Safety by Automatic Braking and Evasive Steering

    E-Print Network [OSTI]

    Gavrila, Dariu M.

    1 Active Pedestrian Safety by Automatic Braking and Evasive Steering C. Keller, T. Dang, H. Fritz of crashes. This paper presents a novel active pedestrian safety system, which combines sensing, situation two complementary approaches for added robustness: motion-based object detection and pedestrian

  4. Tritium Detection Methods and Limitations

    Office of Environmental Management (EM)

    NY (1994). ION CHAMBER DETECTORS * PORTABLE ION CHAMBERS * AREA (ROOM) ION CHAMBERS * EFFLUENT (STACK) ION CHAMBERS PORTABLE ION CHAMBERS 200 to 400 cc active volume 5 to 10 uCim3...

  5. Method for detecting toxic gases

    DOE Patents [OSTI]

    Stetter, Joseph R. (Naperville, IL); Zaromb, Solomon (Hinsdale, IL); Findlay, Jr., Melvin W. (Bolingbrook, IL)

    1991-01-01

    A method capable of detecting low concentrations of a pollutant or other component in air or other gas, utilizing a combination of a heating filament having a catalytic surface of a noble metal for exposure to the gas and producing a derivative chemical product from the component, and an electrochemical sensor responsive to the derivative chemical product for providing a signal indicative of the product. At concentrations in the order of about 1-100 ppm of tetrachloroethylene, neither the heating filament nor the electrochemical sensor is individually capable of sensing the pollutant. In the combination, the heating filament converts the benzyl chloride to one or more derivative chemical products which may be detected by the electrochemical sensor.

  6. Method for detecting toxic gases

    DOE Patents [OSTI]

    Stetter, J.R.; Zaromb, S.; Findlay, M.W. Jr.

    1991-10-08

    A method is disclosed which is capable of detecting low concentrations of a pollutant or other component in air or other gas. This method utilizes a combination of a heating filament having a catalytic surface of a noble metal for exposure to the gas and producing a derivative chemical product from the component. An electrochemical sensor responds to the derivative chemical product for providing a signal indicative of the product. At concentrations in the order of about 1-100 ppm of tetrachloroethylene, neither the heating filament nor the electrochemical sensor is individually capable of sensing the pollutant. In the combination, the heating filament converts the benzyl chloride to one or more derivative chemical products which may be detected by the electrochemical sensor. 6 figures.

  7. Multiplex detection of agricultural pathogens

    DOE Patents [OSTI]

    McBride, Mary Teresa (Brentwood, CA); Slezak, Thomas Richard (Livermore, CA); Messenger, Sharon Lee (Kensington, CA)

    2010-09-14

    Described are kits and methods useful for detection of seven agricultural pathogens (BPSV; BHV; BVD; FMDV; BTV; SVD; and VESV) in a sample. Genomic sequence information from 7 agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

  8. Detection of malicious computer executables

    DOE Patents [OSTI]

    Cai, Dongming M. (Los Alamos, NM); Gokhale, Maya (Los Alamos, NM)

    2009-04-14

    A method of detecting malicious binary executable files is accomplished by inputting a binary executable file; converting the binary executable file to byte hexadecimal text strings; calculating the frequency of each byte pattern in the byte hexadecimal text strings; selecting characteristic byte pattern frequencies as discriminating features; classifying the discriminating features as malicious or benign; labeling the binary executable file as malicious or benign; and outputting the labeled malicious or benign binary executable file.

  9. Detection of a concealed object

    DOE Patents [OSTI]

    Keller, Paul E [Richland, WA; Hall, Thomas E [Kennewick, WA; McMakin, Douglas L [Richland, WA

    2010-11-16

    Disclosed are systems, methods, devices, and apparatus to determine if a clothed individual is carrying a suspicious, concealed object. This determination includes establishing data corresponding to an image of the individual through interrogation with electromagnetic radiation in the 200 MHz to 1 THz range. In one form, image data corresponding to intensity of reflected radiation and differential depth of the reflecting surface is received and processed to detect the suspicious, concealed object.

  10. Detection of a concealed object

    DOE Patents [OSTI]

    Keller, Paul E. (Richland, WA); Hall, Thomas E. (Kennewick, WA); McMakin, Douglas L. (Richland, WA)

    2008-04-29

    Disclosed are systems, methods, devices, and apparatus to determine if a clothed individual is carrying a suspicious, concealed object. This determination includes establishing data corresponding to an image of the individual through interrogation with electromagnetic radiation in the 200 MHz to 1 THz range. In one form, image data corresponding to intensity of reflected radiation and differential depth of the reflecting surface is received and processed to detect the suspicious, concealed object.

  11. Multiplex detection of agricultural pathogens

    DOE Patents [OSTI]

    Siezak, Thomas R.; Gardner, Shea; Torres, Clinton; Vitalis, Elizabeth; Lenhoff, Raymond J.

    2013-01-15

    Described are kits and methods useful for detection of agricultural pathogens in a sample. Genomic sequence information from agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay and/or an array assay to successfully identify the presence or absence of pathogens in a sample.

  12. Compensated intruder-detection systems

    DOE Patents [OSTI]

    McNeilly, David R. (Maryville, TN); Miller, William R. (Andersonville, TN)

    1984-01-01

    Intruder-detection systems in which intruder-induced signals are transmitted through a medium also receive spurious signals induced by changes in a climatic condition affecting the medium. To combat this, signals received from the detection medium are converted to a first signal. The system also provides a reference signal proportional to climate-induced changes in the medium. The first signal and the reference signal are combined for generating therefrom an output signal which is insensitive to the climatic changes in the medium. An alarm is energized if the output signal exceeds a preselected value. In one embodiment, an acoustic cable is coupled to a fence to generate a first electrical signal proportional to movements thereof. False alarms resulting from wind-induced movements of the fence (detection medium) are eliminated by providing an anemometer-driven voltage generator to provide a reference voltage proportional to the velocity of wind incident on the fence. An analog divider receives the first electrical signal and the reference signal as its numerator and denominator inputs, respectively, and generates therefrom an output signal which is insensitive to the wind-induced movements in the fence.

  13. Anomaly Detection in Dynamic Networks

    SciTech Connect (OSTI)

    Turcotte, Melissa

    2014-10-14

    Anomaly detection in dynamic communication networks has many important security applications. These networks can be extremely large and so detecting any changes in their structure can be computationally challenging; hence, computationally fast, parallelisable methods for monitoring the network are paramount. For this reason the methods presented here use independent node and edge based models to detect locally anomalous substructures within communication networks. As a first stage, the aim is to detect changes in the data streams arising from node or edge communications. Throughout the thesis simple, conjugate Bayesian models for counting processes are used to model these data streams. A second stage of analysis can then be performed on a much reduced subset of the network comprising nodes and edges which have been identified as potentially anomalous in the first stage. The first method assumes communications in a network arise from an inhomogeneous Poisson process with piecewise constant intensity. Anomaly detection is then treated as a changepoint problem on the intensities. The changepoint model is extended to incorporate seasonal behavior inherent in communication networks. This seasonal behavior is also viewed as a changepoint problem acting on a piecewise constant Poisson process. In a static time frame, inference is made on this extended model via a Gibbs sampling strategy. In a sequential time frame, where the data arrive as a stream, a novel, fast Sequential Monte Carlo (SMC) algorithm is introduced to sample from the sequence of posterior distributions of the change points over time. A second method is considered for monitoring communications in a large scale computer network. The usage patterns in these types of networks are very bursty in nature and don’t fit a Poisson process model. For tractable inference, discrete time models are considered, where the data are aggregated into discrete time periods and probability models are fitted to the communication counts. In a sequential analysis, anomalous behavior is then identified from outlying behavior with respect to the fitted predictive probability models. Seasonality is again incorporated into the model and is treated as a changepoint model on the transition probabilities of a discrete time Markov process. Second stage analytics are then developed which combine anomalous edges to identify anomalous substructures in the network.

  14. Method and apparatus for enhanced detection of toxic agents

    DOE Patents [OSTI]

    Greenbaum, Elias; Rodriguez, Jr., Miguel; Wu, Jie Jayne; Qi, Hairong

    2013-10-01

    A biosensor based detection of toxins includes enhancing a fluorescence signal by concentrating a plurality of photosynthetic organisms in a fluid into a concentrated region using biased AC electro-osmosis. A measured photosynthetic activity of the photosynthetic organisms is obtained in the concentrated region, where chemical, biological or radiological agents reduce a nominal photosynthetic activity of the photosynthetic organisms. A presence of the chemical, biological and/or radiological agents or precursors thereof, is determined in the fluid based on the measured photosynthetic activity of the concentrated plurality of photosynthetic organisms. A lab-on-a-chip system is used for the concentrating step. The presence of agents is determined from feature vectors, obtained from processing a time dependent signal using amplitude statistics and/or time-frequency analysis, relative to a control signal. A linear discriminant method including support vector machine classification (SVM) is used to identify the agents.

  15. Secondary Energy Infobook Activities (19 Activities)

    K-12 Energy Lesson Plans and Activities Web site (EERE)

    Information about Secondary Energy Infobook, 19 student activities on energy basics for grades 5-8 and 9-12.

  16. Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches

    DOE Patents [OSTI]

    McCutchen-Maloney, Sandra L. (Pleasanton, CA)

    2002-01-01

    Chimeric proteins having both DNA mutation binding activity and nuclease activity are synthesized by recombinant technology. The proteins are of the general formula A-L-B and B-L-A where A is a peptide having DNA mutation binding activity, L is a linker and B is a peptide having nuclease activity. The chimeric proteins are useful for detection and identification of DNA sequence variations including DNA mutations (including DNA damage and mismatches) by binding to the DNA mutation and cutting the DNA once the DNA mutation is detected.

  17. Area Activation 1 Running Head: AREA ACTIVATION

    E-Print Network [OSTI]

    Pomplun, Marc

    Area Activation 1 Running Head: AREA ACTIVATION Advancing Area Activation towards a General Model at Boston 100 Morrissey Boulevard Boston, MA 02125-3393 USA Phone: 617-287-6485 Fax: 617-287-6433 e. Without great effort, human observers clearly outperform every current artificial vision system in tasks

  18. Suspended microchannel resonators for biomolecular detection

    E-Print Network [OSTI]

    Burg, Thomas P. (Thomas Peter)

    2005-01-01

    Microfabricated transducers enable the label-free detection of biological molecules in nanoliter sized samples. Integrating microfluidic detection and sample-preparation can greatly leverage experimental efforts in systems ...

  19. Alternative Neutron Detection Testing Summary

    SciTech Connect (OSTI)

    Kouzes, Richard T.; Ely, James H.; Erikson, Luke E.; Kernan, Warnick J.; Lintereur, Azaree T.; Siciliano, Edward R.; Stromswold, David C.; Woodring, Mitchell L.

    2010-04-08

    Radiation portal monitors used for interdiction of illicit materials at borders include highly sensitive neutron detection systems. The main reason for having neutron detection capability is to detect fission neutrons from plutonium. Most currently deployed radiation portal monitors (RPMs) use neutron detectors based upon 3He-filled gas proportional counters, which are the most common large area neutron detector. This type of neutron detector is used in the TSA and other RPMs installed in international locations and in the Ludlum and Science Applications International Corporation RPMs deployed primarily for domestic applications. There is a declining supply of 3He in the world and, thus, methods to reduce the use of this gas in RPMs with minimal changes to the current system designs and sensitivity to cargo-borne neutrons are being investigated. Four technologies have been identified as being currently commercially available, potential alternative neutron detectors to replace the use of 3He in RPMs. These technologies are: 1) Boron trifluoride-filled proportional counters, 2) Boron-lined proportional counters, 3) Lithium-loaded glass fibers, and 4) Coated wavelength-shifting plastic fibers. Reported here is a summary of the testing carried out at Pacific Northwest National Laboratory on these technologies to date, as well as measurements on 3He tubes at various pressures. Details on these measurements are available in the referenced reports. Sponsors of these tests include the Department of Energy (DOE), Department of Homeland Security (DHS), and the Department of Defense (DoD), as well as internal Pacific Northwest National Laboratory funds.

  20. Radiation Detection Computational Benchmark Scenarios

    SciTech Connect (OSTI)

    Shaver, Mark W.; Casella, Andrew M.; Wittman, Richard S.; McDonald, Ben S.

    2013-09-24

    Modeling forms an important component of radiation detection development, allowing for testing of new detector designs, evaluation of existing equipment against a wide variety of potential threat sources, and assessing operation performance of radiation detection systems. This can, however, result in large and complex scenarios which are time consuming to model. A variety of approaches to radiation transport modeling exist with complementary strengths and weaknesses for different problems. This variety of approaches, and the development of promising new tools (such as ORNL’s ADVANTG) which combine benefits of multiple approaches, illustrates the need for a means of evaluating or comparing different techniques for radiation detection problems. This report presents a set of 9 benchmark problems for comparing different types of radiation transport calculations, identifying appropriate tools for classes of problems, and testing and guiding the development of new methods. The benchmarks were drawn primarily from existing or previous calculations with a preference for scenarios which include experimental data, or otherwise have results with a high level of confidence, are non-sensitive, and represent problem sets of interest to NA-22. From a technical perspective, the benchmarks were chosen to span a range of difficulty and to include gamma transport, neutron transport, or both and represent different important physical processes and a range of sensitivity to angular or energy fidelity. Following benchmark identification, existing information about geometry, measurements, and previous calculations were assembled. Monte Carlo results (MCNP decks) were reviewed or created and re-run in order to attain accurate computational times and to verify agreement with experimental data, when present. Benchmark information was then conveyed to ORNL in order to guide testing and development of hybrid calculations. The results of those ADVANTG calculations were then sent to PNNL for compilation. This is a report describing the details of the selected Benchmarks and results from various transport codes.

  1. Acoustic enhancement for photo detecting devices

    DOE Patents [OSTI]

    Thundat, Thomas G; Senesac, Lawrence R; Van Neste, Charles W

    2013-02-19

    Provided are improvements to photo detecting devices and methods for enhancing the sensitivity of photo detecting devices. A photo detecting device generates an electronic signal in response to a received light pulse. An electro-mechanical acoustic resonator, electrically coupled to the photo detecting device, damps the electronic signal and increases the signal noise ratio (SNR) of the electronic signal. Increased photo detector standoff distances and sensitivities will result.

  2. Foreign WMD Proliferation Detection | National Nuclear Security...

    National Nuclear Security Administration (NNSA)

    WMD Proliferation Detection | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering...

  3. COLLOQUIUM: Starlight Detectives: How Astronomers, Inventors...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Detectives: How Astronomers, Inventors, and Eccentrics Discovered the Modern Universe Professor Alan Hirshfeld University of Massachusetts - Dartmouth Presentation:...

  4. Investigation into Nanostructured Lanthanum Halides and CeBr{sub 3} for Nuclear Radiation Detection

    SciTech Connect (OSTI)

    Guss, P., Guise, R., Mukhopadhyay, S., Yuan, D.

    2011-06-22

    This slide-show presents work on radiation detection with nanostructured lanthanum halides and CeBr{sub 3}. The goal is to extend the gamma energy response on both low and high-energy regimes by demonstrating the ability to detect low-energy x-rays and relatively high-energy activation prompt gamma rays simultaneously using the nano-structured lanthanum bromide, lanthanum fluoride, cerium bromide, or other nanocrystal material. Homogeneous and nano structure cases are compared.

  5. Fire suppression and detection equipment

    SciTech Connect (OSTI)

    E.E. Bates [HSB Professional Loss Control, Lexington, KY (United States)

    2006-01-15

    Inspection and testing guidelines go beyond the 'Code of Federal Regulation'. Title 30 of the US Code of Federal Regulations (30 CFR) contains requirements and references to national standards for inspection, testing and maintenance of fire suppression and detection equipment for mine operators. However, federal requirements have not kept pace with national standards and best practices. The article lists National Fire Protection (NFPA) standards that are referenced by the US Mine Safety and Health Administration (MSHA) in 30 CFR. It then discusses other NFPA Standards excluded from 30 CFR and explains the NFPA standard development process. 2 refs., 3 tabs., 5 photos.

  6. Singularity detection using holder exponent.

    SciTech Connect (OSTI)

    Sohn, H. (Hoon); Robertson, A. N. (Amy N.); Farrar, C. R. (Charles R.)

    2002-01-01

    A signal processing technique called Holder exponent is presented to detect the presence of a discontinuity and when the discontinuity occurs in a dynamic signal. Wavelet transforms are incorporated with the Holder exponent to capture the time varying nature of discontinuities, and a classification procedure is developed to quantify when changes in the Holder exponent are significant, The proposed Holder exponent analysis is applied to acceleration response of a mechanical system with a rattling internal part. The experimental results demonstrate the effectiveness of the Holder exponent for identifying certain types of events that introduce discontinuities into the measured dynamic response data.

  7. Conducting Polymers for Neutron Detection

    SciTech Connect (OSTI)

    Kimblin, Clare; Miller, Kirk; Vogel, Bob; Quam, Bill; McHugh, Harry; Anthony, Glen; Mike, Grover

    2007-12-01

    Conjugated polymers have emerged as an attractive technology for large-area electronic applications. As organic semiconductors, they can be used to make large-area arrays of diodes or transistors using fabrication techniques developed for polymer coatings, such as spraying and screen-printing. We have demonstrated both neutron and alpha detection using diodes made from conjugated polymers and have done preliminary work to integrate a boron carbide layer into the conventional polymer device structure to capture thermal neutrons. The polymer devices appear to be insensitive to gamma rays, due to their small physical thickness and low atomic number.

  8. Multiplex detection of respiratory pathogens

    DOE Patents [OSTI]

    McBride, Mary (Brentwood, CA); Slezak, Thomas (Livermore, CA); Birch, James M. (Albany, CA)

    2012-07-31

    Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

  9. Pulsed helium ionization detection system

    DOE Patents [OSTI]

    Ramsey, Roswitha S. (Knoxville, TN); Todd, Richard A. (Knoxville, TN)

    1987-01-01

    A helium ionization detection system is provided which produces stable operation of a conventional helium ionization detector while providing improved sensitivity and linearity. Stability is improved by applying pulsed dc supply voltage across the ionization detector, thereby modifying the sampling of the detectors output current. A unique pulse generator is used to supply pulsed dc to the detector which has variable width and interval adjust features that allows up to 500 V to be applied in pulse widths ranging from about 150 nsec to about dc conditions.

  10. Pulsed helium ionization detection system

    DOE Patents [OSTI]

    Ramsey, R.S.; Todd, R.A.

    1985-04-09

    A helium ionization detection system is provided which produces stable operation of a conventional helium ionization detector while providing improved sensitivity and linearity. Stability is improved by applying pulsed dc supply voltage across the ionization detector, thereby modifying the sampling of the detectors output current. A unique pulse generator is used to supply pulsed dc to the detector which has variable width and interval adjust features that allows up to 500 V to be applied in pulse widths ranging from about 150 nsec to about dc conditions.

  11. Producing and Detecting Correlated atoms

    E-Print Network [OSTI]

    Christoph I. Westbrook; Martijn Schellekens; Aurélien Perrin; Valentina Krachmalnicoff; Jose Carlos Viana Gomes; Jean-Baptiste Trebbia; Jérôme Estève; Hong Chang; Isabelle Bouchoule; Denis Boiron; Alain Aspect; Tom Jeltes; John McNamara; Wim Hogervorst; Wim Vassen

    2006-09-04

    We discuss experiments to produce and detect atom correlations in a degenerate or nearly degenerate gas of neutral atoms. First we treat the atomic analog of the celebrated Hanbury Brown Twiss experiment, in which atom correlations result simply from interference effects without any atom interactions.We have performed this experiment for both bosons and fermions. Next we show how atom interactions produce correlated atoms using the atomic analog of spontaneous four-wavemixing. Finally, we briefly mention experiments on a one dimensional gas on an atom chip in which correlation effects due to both interference and interactions have been observed.

  12. Immune System for Virus Detection and Elimination

    E-Print Network [OSTI]

    consider the aspects of designing a computer immune system for virus detection and elimination using to modelling the biological immune system in a computer we design a computer immune system for virus detectionImmune System for Virus Detection and Elimination Rune Schmidt Jensen IMM-THESIS-2002-08-31 IMM #12

  13. Automatic Detection and Classification of Sunspot Images

    E-Print Network [OSTI]

    Wolfe, Patrick J.

    Automatic Detection and Classification of Sunspot Images Thomas C. M. Lee tlee with Alex Young and the SaFeDe Solar Imaging Group JSM 2007 ­ p. 1/2 #12;Outline Title: Automatic Detection and Classification of Sunspot Images JSM 2007 ­ p. 2/2 #12;Outline Title: Automatic Detection and Classification

  14. Monocular Pedestrian Detection: Survey and Experiments

    E-Print Network [OSTI]

    Zhu, Zhigang

    1 Monocular Pedestrian Detection: Survey and Experiments Markus Enzweiler1 Student Member, IEEE. Restrictions apply. #12;2 Abstract Pedestrian detection is a rapidly evolving area in computer vision with key. The first part of the paper consists of a survey. We cover the main components of a pedestrian detection

  15. Monocular Pedestrian Detection: Survey and Experiments

    E-Print Network [OSTI]

    Gavrila, Dariu M.

    Monocular Pedestrian Detection: Survey and Experiments Markus Enzweiler, Student Member, IEEE, and Dariu M. Gavrila Abstract--Pedestrian detection is a rapidly evolving area in computer vision with key. The first part of the paper consists of a survey. We cover the main components of a pedestrian detection

  16. Trainable Pedestrian Detection Constantine Papageorgiou Tomaso Poggio

    E-Print Network [OSTI]

    Poggio, Tomaso

    Trainable Pedestrian Detection Constantine Papageorgiou Tomaso Poggio Center for Biological types of objects; we will focus on the task of pedestrian detection. This paradigm of learning from examples allows us to avoid the need for a hand­crafted solution. Unlike many pedestrian detection systems

  17. Molecular Detection and Characterization of Avian Bornavirus 

    E-Print Network [OSTI]

    Mirhosseini, Negin

    2012-07-16

    ...... 42 Figure 7 PCR for the detection of ABV sequences in bird feces using primer mix 3. ........................................................................................... 44 Figure 8 ABV genome organization... Page Table 1 Primers used for detecting ABV ............................................................... 28 Table 2 Primer mixes and PCR conditions to detect ABV .................................... 29 Table 3 Percent nucleotide identity between...

  18. Incipient Crack Detection in Composite Wind Turbine Blades

    SciTech Connect (OSTI)

    Taylor, Stuart G. [Los Alamos National Laboratory; Choi, Mijin [Chonbuk National University, Korea; Jeong, Hyomi [Chonbuk National University, Korea; Jang, Jae Kyeong [Chonbuk National University, Korea; Park, Gyuhae [Chonnam National University, Korea; Farinholt, Kevin [Commonwealth Center for Advanced Manufacturing, VA; Farrar, Charles R. [Los Alamos National Laboratory; Ammerman, Curtt N. [Los Alamos National Laboratory; Todd, Michael D. [Los Alamos National Laboratory; Lee, Jung-Ryul [Chonbuk National University, Korea

    2012-08-28

    This paper presents some analysis results for incipient crack detection in a 9-meter CX-100 wind turbine blade that underwent fatigue loading to failure. The blade was manufactured to standard specifications, and it underwent harmonic excitation at its first resonance using a hydraulically-actuated excitation system until reaching catastrophic failure. This work investigates the ability of an ultrasonic guided wave approach to detect incipient damage prior to the surfacing of a visible, catastrophic crack. The blade was instrumented with piezoelectric transducers, which were used in an active, pitchcatch mode with guided waves over a range of excitation frequencies. The performance results in detecting incipient crack formation in the fiberglass skin of the blade is assessed over the range of frequencies in order to determine the point at which the incipient crack became detectable. Higher excitation frequencies provide consistent results for paths along the rotor blade's carbon fiber spar cap, but performance falls off with increasing excitation frequencies for paths off of the spar cap. Lower excitation frequencies provide more consistent performance across all sensor paths.

  19. Activity Based Costing

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-03-28

    Activity Based Costing (ABC) is method for developing cost estimates in which the project is subdivided into discrete, quantifiable activities or a work unit. This chapter outlines the Activity Based Costing method and discusses applicable uses of ABC.

  20. Early Lung Cancer Detection Program

    Broader source: Energy.gov [DOE]

    Since 2000, DOE has made screening for occupational lung cancer with low-dose helical computed tomography (CT) scans available to workers at high risk for lung cancer. Because former workers undertook essential activities to fulfill the Department's mission, many of them were at risk for lung cancer.

  1. Active stewardship: sustainable future

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Active stewardship: sustainable future Active stewardship: sustainable future Energy sustainability is a daunting task: How do we develop top-notch innovations with some of the...

  2. Spectral analysis method for detecting an element

    DOE Patents [OSTI]

    Blackwood, Larry G [Idaho Falls, ID; Edwards, Andrew J [Idaho Falls, ID; Jewell, James K [Idaho Falls, ID; Reber, Edward L [Idaho Falls, ID; Seabury, Edward H [Idaho Falls, ID

    2008-02-12

    A method for detecting an element is described and which includes the steps of providing a gamma-ray spectrum which has a region of interest which corresponds with a small amount of an element to be detected; providing nonparametric assumptions about a shape of the gamma-ray spectrum in the region of interest, and which would indicate the presence of the element to be detected; and applying a statistical test to the shape of the gamma-ray spectrum based upon the nonparametric assumptions to detect the small amount of the element to be detected.

  3. Single-Pedestrian Detection aided by Multi-pedestrian Detection Wanli Ouyang1,2

    E-Print Network [OSTI]

    Wang, Xiaogang

    Single-Pedestrian Detection aided by Multi-pedestrian Detection Wanli Ouyang1,2 and Xiaogang Wang 1 pedestrians who appear in groups and have inter- action. A new approach is proposed for single-pedestrian detection aided by multi-pedestrian detection. A mixture model of multi-pedestrian detectors is designed

  4. Indirect detection of radiation sources through direct detection of radiolysis products

    DOE Patents [OSTI]

    Farmer, Joseph C. (Tracy, CA); Fischer, Larry E. (Los Gatos, CA); Felter, Thomas E. (Livermore, CA)

    2010-04-20

    A system for indirectly detecting a radiation source by directly detecting radiolytic products. The radiation source emits radiation and the radiation produces the radiolytic products. A fluid is positioned to receive the radiation from the radiation source. When the fluid is irradiated, radiolytic products are produced. By directly detecting the radiolytic products, the radiation source is detected.

  5. Cellular telephone-based radiation detection instrument

    DOE Patents [OSTI]

    Craig, William W. (Pittsburg, CA); Labov, Simon E. (Berkeley, CA)

    2011-06-14

    A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

  6. Buried object detection in GPR images

    DOE Patents [OSTI]

    Paglieroni, David W; Chambers, David H; Bond, Steven W; Beer, W. Reginald

    2014-04-29

    A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

  7. Vertical flow chemical detection portal

    DOE Patents [OSTI]

    Linker, Kevin L. (Albuquerque, NM); Hannum, David W. (Albuquerque, NM); Conrad, Frank James (Russellville, SC)

    1999-01-01

    A portal apparatus for screening objects or persons for the presence of trace amounts of chemical substances such as illicit drugs or explosives. The apparatus has a test space, in which a person may stand, defined by two generally upright sides spanned by a horizontal transom. One or more fans in the transom generate a downward air flow (uni-directional) within the test space. The air flows downwardly from a high pressure upper zone, past the object or person to be screened. Air moving past the object dislodges from the surface thereof both volatile and nonvolatile particles of the target substance. The particles are entrained into the air flow which continues flowing downward to a lower zone of reduced pressure, where the particle-bearing air stream is directed out of the test space and toward preconcentrator and detection components. The sides of the portal are specially configured to partially contain and maintain the air flow.

  8. Vertical flow chemical detection portal

    DOE Patents [OSTI]

    Linker, K.L.; Hannum, D.W.; Conrad, F.J.

    1999-06-22

    A portal apparatus is described for screening objects or persons for the presence of trace amounts of chemical substances such as illicit drugs or explosives. The apparatus has a test space, in which a person may stand, defined by two generally upright sides spanned by a horizontal transom. One or more fans in the transom generate a downward air flow (uni-directional) within the test space. The air flows downwardly from a high pressure upper zone, past the object or person to be screened. Air moving past the object dislodges from the surface thereof both volatile and nonvolatile particles of the target substance. The particles are entrained into the air flow which continues flowing downward to a lower zone of reduced pressure, where the particle-bearing air stream is directed out of the test space and toward preconcentrator and detection components. The sides of the portal are specially configured to partially contain and maintain the air flow. 3 figs.

  9. Intrusion detection using secure signatures

    DOE Patents [OSTI]

    Nelson, Trent Darnel; Haile, Jedediah

    2014-09-30

    A method and device for intrusion detection using secure signatures comprising capturing network data. A search hash value, value employing at least one one-way function, is generated from the captured network data using a first hash function. The presence of a search hash value match in a secure signature table comprising search hash values and an encrypted rule is determined. After determining a search hash value match, a decryption key is generated from the captured network data using a second hash function, a hash function different form the first hash function. One or more of the encrypted rules of the secure signatures table having a hash value equal to the generated search hash value are then decrypted using the generated decryption key. The one or more decrypted secure signature rules are then processed for a match and one or more user notifications are deployed if a match is identified.

  10. Methanol detection in M82

    E-Print Network [OSTI]

    S. Martín; J. Martín-Pintado; R. Mauersberger

    2006-03-07

    We present a multilevel study of the emission of methanol, detected for the first time in this galaxy, and discuss the origin of its emission. The high observed methanol abundance of a few 10^-9 can only be explained if injection of methanol from dust grains is taken into account. While the overall [CH3OH]/[NH3] ratio is much larger than observed towards other starbursts, the dense high excitation component shows a similar value to that found in NGC 253 and Maffei 2. Our observations suggest the molecular material in M 82 to be formed by dense warm cores, shielded from the UV radiation and similar to the molecular clouds in other starbursts, surrounded by a less dense photodissociated halo. The dense warm cores are likely the location of recent and future star formation within M 82.

  11. Explosives detection system and method

    DOE Patents [OSTI]

    Reber, Edward L. (Idaho Falls, ID); Jewell, James K. (Idaho Falls, ID); Rohde, Kenneth W. (Idaho Falls, ID); Seabury, Edward H. (Idaho Falls, ID); Blackwood, Larry G. (Idaho Falls, ID); Edwards, Andrew J. (Idaho Falls, ID); Derr, Kurt W. (Idaho Falls, ID)

    2007-12-11

    A method of detecting explosives in a vehicle includes providing a first rack on one side of the vehicle, the rack including a neutron generator and a plurality of gamma ray detectors; providing a second rack on another side of the vehicle, the second rack including a neutron generator and a plurality of gamma ray detectors; providing a control system, remote from the first and second racks, coupled to the neutron generators and gamma ray detectors; using the control system, causing the neutron generators to generate neutrons; and performing gamma ray spectroscopy on spectra read by the gamma ray detectors to look for a signature indicative of presence of an explosive. Various apparatus and other methods are also provided.

  12. Sequential detection of web defects

    DOE Patents [OSTI]

    Eichel, Paul H. (Albuquerque, NM); Sleefe, Gerard E. (Cedar Crest, NM); Stalker, K. Terry (Albuquerque, NM); Yee, Amy A. (Albuquerque, NM)

    2001-01-01

    A system for detecting defects on a moving web having a sequential series of identical frames uses an imaging device to form a real-time camera image of a frame and a comparitor to comparing elements of the camera image with corresponding elements of an image of an exemplar frame. The comparitor provides an acceptable indication if the pair of elements are determined to be statistically identical; and a defective indication if the pair of elements are determined to be statistically not identical. If the pair of elements is neither acceptable nor defective, the comparitor recursively compares the element of said exemplar frame with corresponding elements of other frames on said web until one of the acceptable or defective indications occur.

  13. Community detection for interaction networks

    E-Print Network [OSTI]

    Crane, Harry

    2015-01-01

    In many applications, it is common practice to obtain a network from interaction counts by thresholding each pairwise count at a prescribed value. Our analysis calls attention to the dependence of certain methods, notably Newman--Girvan modularity, on the choice of threshold. Essentially, the threshold either separates the network into clusters automatically, making the algorithm's job trivial, or erases all structure in the data, rendering clustering impossible. By fitting the original interaction counts as given, we show that minor modifications to classical statistical methods outperform the prevailing approaches for community detection from interaction datasets. We also introduce a new hidden Markov model for inferring community structures that vary over time. We demonstrate each of these features on three real datasets: the karate club dataset, voting data from the U.S.\\ Senate (2001--2003), and temporal voting data for the U.S. Supreme Court (1990--2004).

  14. Oxygen detection using evanescent fields

    DOE Patents [OSTI]

    Duan, Yixiang (Los Alamos, NM); Cao, Weenqing (Los Alamos, NM)

    2007-08-28

    An apparatus and method for the detection of oxygen using optical fiber based evanescent light absorption. Methylene blue was immobilized using a sol-gel process on a portion of the exterior surface of an optical fiber for which the cladding has been removed, thereby forming an optical oxygen sensor. When light is directed through the optical fiber, transmitted light intensity varies as a result of changes in the absorption of evanescent light by the methylene blue in response to the oxygen concentration to which the sensor is exposed. The sensor was found to have a linear response to oxygen concentration on a semi-logarithmic scale within the oxygen concentration range between 0.6% and 20.9%, a response time and a recovery time of about 3 s, ant to exhibit good reversibility and repeatability. An increase in temperature from 21.degree. C. to 35.degree. C. does not affect the net absorption of the sensor.

  15. Boron-10 ABUNCL Active Testing

    SciTech Connect (OSTI)

    Kouzes, Richard T.; Ely, James H.; Lintereur, Azaree T.; Siciliano, Edward R.

    2013-07-09

    The Department of Energy Office of Nuclear Safeguards and Security (NA-241) is supporting the project Coincidence Counting With Boron-Based Alternative Neutron Detection Technology at Pacific Northwest National Laboratory (PNNL) for the development of a 3He proportional counter alternative neutron coincidence counter. The goal of this project is to design, build and demonstrate a system based upon 10B-lined proportional tubes in a configuration typical for 3He-based coincidence counter applications. This report provides results from testing of the active mode of the General Electric Reuter-Stokes Alternative Boron-Based Uranium Neutron Coincidence Collar (ABUNCL) at Los Alamos National Laboratory using sources and fuel pins.

  16. Mass spectrometry-based methods for detection and differentiation of botulinum neurotoxins

    DOE Patents [OSTI]

    Schmidt, Jurgen G. (Los Alamos, NM); Boyer, Anne E. (Atlanta, GA); Kalb, Suzanne R. (Atlanta, GA); Moura, Hercules (Tucker, GA); Barr, John R. (Suwannee, GA); Woolfitt, Adrian R. (Atlanta, GA)

    2009-11-03

    The present invention is directed to a method for detecting the presence of clostridial neurotoxins in a sample by mixing a sample with a peptide that can serve as a substrate for proteolytic activity of a clostridial neurotoxin; and measuring for proteolytic activity of a clostridial neurotoxin by a mass spectroscopy technique. In one embodiment, the peptide can have an affinity tag attached at two or more sites.

  17. Spot test kit for explosives detection

    DOE Patents [OSTI]

    Pagoria, Philip F; Whipple, Richard E; Nunes, Peter J; Eckels, Joel Del; Reynolds, John G; Miles, Robin R; Chiarappa-Zucca, Marina L

    2014-03-11

    An explosion tester system comprising a body, a lateral flow membrane swab unit adapted to be removeably connected to the body, a first explosives detecting reagent, a first reagent holder and dispenser operatively connected to the body, the first reagent holder and dispenser containing the first explosives detecting reagent and positioned to deliver the first explosives detecting reagent to the lateral flow membrane swab unit when the lateral flow membrane swab unit is connected to the body, a second explosives detecting reagent, and a second reagent holder and dispenser operatively connected to the body, the second reagent holder and dispenser containing the second explosives detecting reagent and positioned to deliver the second explosives detecting reagent to the lateral flow membrane swab unit when the lateral flow membrane swab unit is connected to the body.

  18. Tissue-based standoff biosensors for detecting chemical warfare agents

    DOE Patents [OSTI]

    Greenbaum, Elias; Sanders, Charlene A.

    2003-11-18

    A tissue-based, deployable, standoff air quality sensor for detecting the presence of at least one chemical or biological warfare agent, includes: a cell containing entrapped photosynthetic tissue, the cell adapted for analyzing photosynthetic activity of the entrapped photosynthetic tissue; means for introducing an air sample into the cell and contacting the air sample with the entrapped photosynthetic tissue; a fluorometer in operable relationship with the cell for measuring photosynthetic activity of the entrapped photosynthetic tissue; and transmitting means for transmitting analytical data generated by the fluorometer relating to the presence of at least one chemical or biological warfare agent in the air sample, the sensor adapted for deployment into a selected area.

  19. Selective chemical detection by energy modulation of sensors

    DOE Patents [OSTI]

    Stetter, J.R.; Otagawa, T.

    1985-05-20

    A portable instrument for use in the field in detecting, identifying, and quantifying a component of a sampled fluid includes a sensor which chemically reacts with the component of interest or a derivative thereof, an electrical heating filament for heating the sample before it is applied to the sensor, and modulating means for continuously varying the temperature of the filament (and hence the reaction rate) between two values sufficient to produce the chemical reaction. In response to this thermal modulation, the sensor produces a modulated output signal, the modulation of which is a function of the activation energy of the chemical reaction, which activation energy is specific to the particular component of interest and its concentration. Microprocessor means compares the modulated output signal with standard responses for a plurality of components to identify and quantify the particular component of interest. 4 figs.

  20. Detection and prevention of mycoplasma hominis infection

    DOE Patents [OSTI]

    DelVecchio, Vito G. (Scranton, PA); Gallia, Gary L. (Philadelphia, PA); McCleskey, Ferne K. (San Antonio, TX)

    1997-01-21

    The present invention is directed to a rapid and sensitive method for detecting Mycoplasma hominis using M. hominis-specific probes, oligonucleotides or antibodies. In particular a target sequence can be amplified by in vitro nucleic acid amplification techniques, detected by nucleic acid hybridization using the subject probes and oligonucleotides or detected by immunoassay using M. hominis-specific antibodies. M. hominis-specific nucleic acids which do not recognize or hybridize to genomic nucleic acid of other Mycoplasma species are also provided.

  1. Transport Test Problems for Radiation Detection Scenarios

    SciTech Connect (OSTI)

    Shaver, Mark W.; Miller, Erin A.; Wittman, Richard S.; McDonald, Benjamin S.

    2012-09-30

    This is the final report and deliverable for the project. It is a list of the details of the test cases for radiation detection scenarios.

  2. Prof. Alessandro De Luca Collision detection

    E-Print Network [OSTI]

    De Luca, Alessandro

    European project (2011-15) #12;Collision detection in industrial robots ! advanced option available torque joint torque caused by link collision inertia matrix Coriolis/centrifugal (with "good

  3. Communication error detection using facial expressions

    E-Print Network [OSTI]

    Wang, Sy Bor, 1976-

    2008-01-01

    Automatic detection of communication errors in conversational systems typically rely only on acoustic cues. However, perceptual studies have indicated that speakers do exhibit visual communication error cues passively ...

  4. Nuclear Detonation Detection | National Nuclear Security Administratio...

    National Nuclear Security Administration (NNSA)

    the entire planet from space to detect and report surface, atmospheric, or space nuclear detonations; produces and updates the regional geophysical datasets enabling...

  5. SPITZER INFRARED SPECTROGRAPH DETECTION OF MOLECULAR HYDROGEN...

    Office of Scientific and Technical Information (OSTI)

    SPITZER INFRARED SPECTROGRAPH DETECTION OF MOLECULAR HYDROGEN ROTATIONAL EMISSION TOWARDS TRANSLUCENT CLOUDS Citation Details In-Document Search Title: SPITZER INFRARED...

  6. Radionuclide detection devices and associated methods

    DOE Patents [OSTI]

    Mann, Nicholas R. (Rigby, ID); Lister, Tedd E. (Idaho Falls, ID); Tranter, Troy J. (Idaho Falls, ID)

    2011-03-08

    Radionuclide detection devices comprise a fluid cell comprising a flow channel for a fluid stream. A radionuclide collector is positioned within the flow channel and configured to concentrate one or more radionuclides from the fluid stream onto at least a portion of the radionuclide collector. A scintillator for generating scintillation pulses responsive to an occurrence of a decay event is positioned proximate at least a portion of the radionuclide collector and adjacent to a detection system for detecting the scintillation pulses. Methods of selectively detecting a radionuclide are also provided.

  7. DN detection during SLSF tests

    SciTech Connect (OSTI)

    Braid, T.H.; Harper, H.A.; Wilson, R.E.; Baldwin, R.D.; Gilbert, D.M.; Baxter, D.E.; Gillins, R.L.; Jeffries, G.L.

    1982-01-01

    During two tests in the Sodium Loop Safety Facility (W2 and P4), two systems were operated to detect delayed neutrons from exposed fuel. One monitored directly the sodium in the in-pile loop with a transit delay from the flux region of approx.2 seconds; the other conducted a sample stream of sodium to external detectors with a transit delay which could be varied from approx.10 to approx. 40 seconds. Detectors of a wide range of sensitivity were operated in pulse and current mode; DN signals varying from <1 mm/sup 2/ recoil to many grams of molten fuel could be recorded reliably without saturation. During the W2 and P4 tests a continuous DN record was made. Massive fuel failure signals were observed during reactor transients in both tests, including events interpreted as fuel melting and exposure of large areas. The steady signal from the blockage in P4 was studied as a function of reactor power and sodium temperature.

  8. Detecting Tampering in Random Graphs

    E-Print Network [OSTI]

    Pinsky, Ross G

    2012-01-01

    Let $\\mathcal{G}_n=(V_n,E_n)$ be a growing sequence of deterministic finite graphs, with $V_n$ denoting the vertices and $E_n$ denoting the edges. Consider the random graph $\\mathcal{G}_n(p_n)=(V_n, E_n(p_n))$ obtained by including any given edge with probability $p_n$, independent of other edges, and let $P_n^{p_n}$ denote the corresponding probability measure on $\\mathcal{G}_n$. Now tamper with the random graph in some regular way. For example, if $\\mathcal{G}_n$ is the complete graph on $n$ vertices, so that $\\mathcal{G}_n(p_n)$ is the Erdos-Renyi graph, then one might tamper with it by disconnecting all the edges of a randomly chosen vertex, or by adding all the edges of a randomly chosen Hamiltonian path from $\\mathcal{G}_n$, or by adding all the edges of a randomly chosen clique of order $k_n$ from $\\mathcal{G}_n$. Denote the resulting induced measure on $\\mathcal{G}_n$ by $P_n^{p_n,\\text{tamper}}$. The tampering is called \\it detectable\\rm\\ if $\\lim_{n\\to\\infty}||P_n^{p_n,\\text{tamper}}-P_n^{p_n}||_{\\t...

  9. Neutron Interrogation System For Underwater Threat Detection And Identification

    SciTech Connect (OSTI)

    Barzilov, Alexander P.; Novikov, Ivan S.; Womble, Phil C.

    2009-03-10

    Wartime and terrorist activities, training and munitions testing, dumping and accidents have generated significant munitions contamination in the coastal and inland waters in the United States and abroad. Although current methods provide information about the existence of the anomaly (for instance, metal objects) in the sea bottom, they fail to identify the nature of the found objects. Field experience indicates that often in excess of 90% of objects excavated during the course of munitions clean up are found to be non-hazardous items (false alarm). The technology to detect and identify waterborne or underwater threats is also vital for protection of critical infrastructures (ports, dams, locks, refineries, and LNG/LPG). We are proposing a compact neutron interrogation system, which will be used to confirm possible threats by determining the chemical composition of the suspicious underwater object. The system consists of an electronic d-T 14-MeV neutron generator, a gamma detector to detect the gamma signal from the irradiated object and a data acquisition system. The detected signal then is analyzed to quantify the chemical elements of interest and to identify explosives or chemical warfare agents.

  10. A Vertical Hydrophone Array Coupled via Inductive Modem for Detecting Deep-Ocean Seismic and

    E-Print Network [OSTI]

    Bohnenstiehl, Delwayne

    A Vertical Hydrophone Array Coupled via Inductive Modem for Detecting Deep-Ocean Seismic synchronization methods based on three-wire serial or NTP network interface, it only requires an insulated single is active with seismicity and submarine eruptions. The results of the four-month long monitoring

  11. MultiQ: Automated Detection of Multiple Bottleneck Capacities Along a Path

    E-Print Network [OSTI]

    . It uses equally-spaced mode gaps in TCP flows' packet interarrival time distributions to detect multiple multiQ is pas- sive, it achieves the same accuracy as Pathrate, which is active. Categories and Subject- formation is vital for network modeling and other applications. We present multiQ, the first passive

  12. HOUSEHOLD AND STRUCTURAL INSECTS Accuracy of Trained Canines for Detecting Bed Bugs (Hemiptera

    E-Print Network [OSTI]

    Wang, Changlu

    HOUSEHOLD AND STRUCTURAL INSECTS Accuracy of Trained Canines for Detecting Bed Bugs (Hemiptera) compared the effectiveness of visual inspection, passive pitfall-style interceptors, and active (with lure number of infestations was de- tected by passive pitfall-style monitors (70%) placed under the legs

  13. Neutrinos and Arms Control: Thinking Big about Detection of Neutrinos from

    E-Print Network [OSTI]

    Learned, John

    detect and monitor any new reactor, in particular one which may be producing illicit nuclear weapons FOR INTERNATIONAL REACTOR MONITORING In the present world political environment when nuclear weapons capability of reactor activ- ities around the world, with the speci c focus of monitoring nuclear weapons fuel

  14. Carbon-on-Metal Films for Surface Plasmon Resonance Detection of Matthew R. Lockett,

    E-Print Network [OSTI]

    Carbon-on-Metal Films for Surface Plasmon Resonance Detection of DNA Arrays Matthew R. Lockett of a lamellar structure in which a thin layer of amorphous carbon is deposited onto a surface plasmon-active gold thin film (Figure 1a). Carbon-based surfaces are readily modified with biomolecules of interest

  15. Fraud Detection in ERP Systems using Scenario Asadul K. Islam1

    E-Print Network [OSTI]

    Flegel, Ulrich

    112 Fraud Detection in ERP Systems using Scenario Matching Asadul K. Islam1 , Malcom Corney1.raub, ulrich.flegel}@sap.com Abstract. ERP systems generally implement controls to prevent certain common kinds of fraudulent activity in ERP systems. We include the description of six fraud scenarios and the process

  16. 2001 Progress on a Direct Brain Interface Based on Detection of ERPs in ECoG

    E-Print Network [OSTI]

    Fessler, Jeffrey A.

    2001 Progress on a Direct Brain Interface Based on Detection of ERPs in ECoG The University of event- related potentials (ERPs) in ECoG. First, averaged ECoG templates are developed using triggered. The brain activity that forms an ERP in the time domain also appears as frequency- specific changes

  17. Statistical language analysis for automatic exfiltration event detection.

    SciTech Connect (OSTI)

    Robinson, David Gerald

    2010-04-01

    This paper discusses the recent development a statistical approach for the automatic identification of anomalous network activity that is characteristic of exfiltration events. This approach is based on the language processing method eferred to as latent dirichlet allocation (LDA). Cyber security experts currently depend heavily on a rule-based framework for initial detection of suspect network events. The application of the rule set typically results in an extensive list of uspect network events that are then further explored manually for suspicious activity. The ability to identify anomalous network events is heavily dependent on the experience of the security personnel wading through the network log. Limitations f this approach are clear: rule-based systems only apply to exfiltration behavior that has previously been observed, and experienced cyber security personnel are rare commodities. Since the new methodology is not a discrete rule-based pproach, it is more difficult for an insider to disguise the exfiltration events. A further benefit is that the methodology provides a risk-based approach that can be implemented in a continuous, dynamic or evolutionary fashion. This permits uspect network activity to be identified early with a quantifiable risk associated with decision making when responding to suspicious activity.

  18. KPA Activity Number

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    September 2002 Page 1 KPA Activity Number KPA Activity SEM Section SME Work Product SQSE Web Site http:cio.doe.govsqse REQUIREMENTS MANAGEMENT RM-1 The software engineering...

  19. Leak detection on an ethylene pipeline

    SciTech Connect (OSTI)

    Hamande, A.; Condacse, V.; Modisette, J.

    1995-12-31

    A model-based leak detection system has been in operation on the Solvay et Cie ethylene pipeline from Antwerp to Jemeppe on Sambre since 1989. The leak detection system, which is the commercial product PLDS of Modisette Associations, Inc., was originally installed by the supplier. Since 1991, all system maintenance and configuration changes have been done by Solvay et Cie personnel. Many leak tests have been performed, and adjustments have been made in the configuration and the automatic tuning parameters. The leak detection system is currently able to detect leaks of 2 tonnes/hour in 11 minutes with accurate location. Larger leaks are detected in about 2 minutes. Leaks between 0.5 and 1 tonne per hour are detected after several hours. (The nominal mass flow in the pipeline is 15 tonnes/hour, with large fluctuations.) Leaks smaller than 0.5 tonnes per hour are not detected, with the alarm thresholds set at levels to avoid false alarms. The major inaccuracies of the leak detection system appear to be associated with the ethylene temperatures.

  20. Bioluminescent bioreporter integrated circuit detection methods

    DOE Patents [OSTI]

    Simpson, Michael L.; Paulus, Michael J.; Sayler, Gary S.; Applegate, Bruce M.; Ripp, Steven A.

    2005-06-14

    Disclosed are monolithic bioelectronic devices comprising a bioreporter and an OASIC. These bioluminescent bioreporter integrated circuit are useful in detecting substances such as pollutants, explosives, and heavy-metals residing in inhospitable areas such as groundwater, industrial process vessels, and battlefields. Also disclosed are methods and apparatus for detection of particular analytes, including ammonia and estrogen compounds.

  1. Anomaly Intrusion Detection in Dynamic Execution Environments

    E-Print Network [OSTI]

    New Mexico, University of

    of Microsoft's .NET project [10]. These technologies will further decouple hardware and software, allowing intrusion detection with extremely low performance penal- ties. Because each virtual machine (VM to improve intrusion detection[27, 36, 3]. Several such systems have been constructed, many with the idea

  2. Quantum nonlocality with arbitrary limited detection efficiency

    E-Print Network [OSTI]

    Gilles Pütz; Nicolas Gisin

    2015-07-17

    The demonstration and use of nonlocality, as defined by Bell's theorem, rely strongly on dealing with non-detection events due to losses and detector inefficiencies. Otherwise, the so-called detection loophole could be exploited. The only way to avoid this is to have detection efficiencies that are above a certain threshold. We introduce the intermediate assumption of limited detection efficiency, e.g. in each run of the experiment the overall detection efficiency is lower bounded by $\\eta_{min} > 0$. Hence, in an adversarial scenario, the adversaries have arbitrary large but not full control over the inefficiencies. We analyze the set of possible correlations that fulfil Limited Detection Locality (LDL) and show that they necessarily satisfy some linear Bell-like inequalities. We prove that quantum theory predicts violation of one of these inequalities for all $\\eta_{min} > 0$. Hence, nonlocality can be demonstrated with arbitrarily small limited detection efficiencies. Finally we propose a generalized scheme that uses this characterization to deal with detection inefficiencies, which interpolates between the two usual schemes, postselection and outcome assignment.

  3. Multivariate Change Detection in Multispectral, Multitemporal Images

    E-Print Network [OSTI]

    Multivariate Change Detection in Multispectral, Multitemporal Images Knut Conradsen Allan Aasbjerg, Building 321 DK-2800 Lyngby, Denmark Abstract This paper introduces a new orthogonal transfonn the multivariate change detection (MeD) transfonn based on an established multivariate statistical tech- nique

  4. Pedestrian Detection: A Benchmark Piotr Dollar1

    E-Print Network [OSTI]

    Zhu, Zhigang

    Pedestrian Detection: A Benchmark Piotr Doll´ar1 Christian Wojek2 Bernt Schiele2 Pietro Perona1 1 Darmstadt {pdollar,perona}@caltech.edu {wojek,schiele}@cs.tu-darmstadt.de Abstract Pedestrian detection- ing public datasets. To continue the rapid rate of innova- tion, we introduce the Caltech Pedestrian

  5. Compressed Sensing Meets Change-Point Detection

    E-Print Network [OSTI]

    Xie, Yao

    of weak signals: How to use signal correlation? Technical Report, 2011. 2/53 #12;Solar flare detection June, 2012. I solar storm: a large explosion in the sun's atmosphere I a direct hit by solar storm can shut down power lines, and destroy airplane communications I predict major solar storms: detecting

  6. Capability of environmental sampling to detect undeclared cask openings

    SciTech Connect (OSTI)

    Beckstead, L.W.; Efurd, D.W.; Hemberger, P.H.; Abhold, M.E.; Eccleston, G.W.

    1997-12-01

    The goal of this study is to determine the signatures that would allow monitors to detect diversion of nuclear fuel (by a diverter) from a storage area such as a geological repository. Due to the complexity of operations surrounding disposal of spent nuclear fuel in a geologic repository, there are several places that a diversion of fuel could take place. After the canister that contains the fuel rods is breached, the diverter would require a hot cell to process or repackage the fuel. A reference repository and possible diversion scenarios are discussed. When a canister is breached, or during reprocessing to extract nuclear weapons material (primarily Pu), several important isotopes or signatures including tritium, {sup 85}Kr, and {sup 129}I are released to the surrounding environment and have the potential for analysis. Estimates of release concentrations of the key signatures from the repository under a hypothetical diversion scenario are presented and discussed. Gas analysis data collected from above-ground storage casks at Idaho National Engineering and Environmental Laboratory (INEEL) Test Area North (TAN) are included and discussed in the report. In addition, LANL participated in gas sampling of one TAN cask, the Castor V/21, in July 1997. Results of xenon analysis from the cask gas sample are presented and discussed. The importance of global fallout and recent commercial reprocessing activities and their effects on repository monitoring are discussed. Monitoring and instrumental equipment for analysis of the key signature isotopes are discussed along with limits of detection. A key factor in determining if diversion activities are in progress at a repository is the timeliness of detection and analysis of the signatures. Once a clandestine operation is suspected, analytical data should be collected as quickly as possible to support any evidence of diversion.

  7. Characterization of cellulolytic activity from digestive fluids of Dissosteira carolina (Orthoptera: Acrididae)

    E-Print Network [OSTI]

    Jurat-Fuentes, Juan Luis

    Characterization of cellulolytic activity from digestive fluids of Dissosteira carolina (Orthoptera Available online xxxx Keywords: Cellulase Grasshopper Orthoptera Endoglucanase Acrididae Digestive fluid in digestive fluids of D. carolina. In zymograms using carboxymethylcellulose (CMC) as substrate, we detected

  8. Structural Health Monitoring with Piezoelectric Wafer Active Sensors for Space Applications

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Structural Health Monitoring with Piezoelectric Wafer Active Sensors for Space Applications Adrian detection and structural health monitoring. Where appropriate, comparison between different methods-coupling coefficient I. Introduction STRUCTURAL health monitoring (SHM) is an emerging research area with multiple

  9. Detecting concentration changes with cooperative receptors

    E-Print Network [OSTI]

    Bo, Stefano

    2015-01-01

    Cells constantly need to monitor the state of the environment to detect changes and timely respond. The detection of concentration changes of a ligand by a set of receptors can be cast as a problem of hypothesis testing, and the cell viewed as a Neyman-Pearson detector. Within this framework, we investigate the role of receptor cooperativity in improving the cell's ability to detect changes. We find that cooperativity decreases the probability of missing an occurred change. This becomes especially beneficial when difficult detections have to be made. Concerning the influence of cooperativity on how fast a desired detection power is achieved, we find in general that there is an optimal value at finite levels of cooperation, even though easy discrimination tasks can be performed more rapidly by noncooperative receptors.

  10. Intrusion Detection 1 02/09/00 Computer System Intrusion Detection

    E-Print Network [OSTI]

    Lee, Ruby B.

    Intrusion Detection 1 02/09/00 Computer System Intrusion Detection: A Survey1 Anita K. Jones in computer systems increases in importance as computers are increasingly integrated into the systems that we detection as performed in software in the context of operating systems for a single computer, a distributed

  11. Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors VICTOR of structural damage such as fatigue cracks and corrosion. Two main detection strategies are considered: (a) the wave propagation method for far-field damage detection; and (b) the electro-mechanical (E/M) impedance

  12. Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Damage Identification in Aging Aircraft Structures with Piezoelectric Wafer Active Sensors VICTOR the onset and progress of structural damage such as fatigue cracks and corrosion. Two main detection strategies are considered: (a) the wave propagation method for far-field damage detection; and (b

  13. Methods for radiation detection and characterization using a multiple detector probe

    DOE Patents [OSTI]

    Akers, Douglas William; Roybal, Lyle Gene

    2014-11-04

    Apparatuses, methods, and systems relating to radiological characterization of environments are disclosed. Multi-detector probes with a plurality of detectors in a common housing may be used to substantially concurrently detect a plurality of different radiation activities and types. Multiple multi-detector probes may be used in a down-hole environment to substantially concurrently detect radioactive activity and contents of a buried waste container. Software may process, analyze, and integrate the data from the different multi-detector probes and the different detector types therein to provide source location and integrated analysis as to the source types and activity in the measured environment. Further, the integrated data may be used to compensate for differential density effects and the effects of radiation shielding materials within the volume being measured.

  14. Smart Sensing Strategies: Insights from a Biological Active Sensing System

    E-Print Network [OSTI]

    Nelson, Mark E.

    of smart sensing systems in diverse engineering applications. Certain freshwater fish from South America and Africa, known as weakly electric fish, use self-generated electrical energy to actively probe their environment. The fish emit millivolt-level electrical discharges and detect microvolt-level voltage

  15. Sensor for detecting changes in magnetic fields

    DOE Patents [OSTI]

    Praeg, Walter F. (Palos Park, IL)

    1981-01-01

    A sensor for detecting changes in the magnetic field of the equilibrium-field coil of a Tokamak plasma device comprises a pair of bifilar wires disposed circumferentially, one inside and one outside the equilibrium-field coil. Each is shorted at one end. The difference between the voltages detected at the other ends of the bifilar wires provides a measure of changing flux in the equilibrium-field coil. This difference can be used to detect faults in the coil in time to take action to protect the coil.

  16. Colorimetric detection of uranium in water

    DOE Patents [OSTI]

    DeVol, Timothy A. (Clemson, SC); Hixon, Amy E. (Piedmont, SC); DiPrete, David P. (Evans, GA)

    2012-03-13

    Disclosed are methods, materials and systems that can be used to determine qualitatively or quantitatively the level of uranium contamination in water samples. Beneficially, disclosed systems are relatively simple and cost-effective. For example, disclosed systems can be utilized by consumers having little or no training in chemical analysis techniques. Methods generally include a concentration step and a complexation step. Uranium concentration can be carried out according to an extraction chromatographic process and complexation can chemically bind uranium with a detectable substance such that the formed substance is visually detectable. Methods can detect uranium contamination down to levels even below the MCL as established by the EPA.

  17. Thermal wake/vessel detection technique

    DOE Patents [OSTI]

    Roskovensky, John K. (Albuquerque, NM); Nandy, Prabal (Albuquerque, NM); Post, Brian N (Albuquerque, NM)

    2012-01-10

    A computer-automated method for detecting a vessel in water based on an image of a portion of Earth includes generating a thermal anomaly mask. The thermal anomaly mask flags each pixel of the image initially deemed to be a wake pixel based on a comparison of a thermal value of each pixel against other thermal values of other pixels localized about each pixel. Contiguous pixels flagged by the thermal anomaly mask are grouped into pixel clusters. A shape of each of the pixel clusters is analyzed to determine whether each of the pixel clusters represents a possible vessel detection event. The possible vessel detection events are represented visually within the image.

  18. High sensitivity leak detection method and apparatus

    DOE Patents [OSTI]

    Myneni, G.R.

    1994-09-06

    An improved leak detection method is provided that utilizes the cyclic adsorption and desorption of accumulated helium on a non-porous metallic surface. The method provides reliable leak detection at superfluid helium temperatures. The zero drift that is associated with residual gas analyzers in common leak detectors is virtually eliminated by utilizing a time integration technique. The sensitivity of the apparatus of this disclosure is capable of detecting leaks as small as 1 [times] 10[sup [minus]18] atm cc sec[sup [minus]1]. 2 figs.

  19. High sensitivity leak detection method and apparatus

    DOE Patents [OSTI]

    Myneni, Ganapatic R. (Grafton, VA)

    1994-01-01

    An improved leak detection method is provided that utilizes the cyclic adsorption and desorption of accumulated helium on a non-porous metallic surface. The method provides reliable leak detection at superfluid helium temperatures. The zero drift that is associated with residual gas analyzers in common leak detectors is virtually eliminated by utilizing a time integration technique. The sensitivity of the apparatus of this disclosure is capable of detecting leaks as small as 1.times.10.sup.-18 atm cc sec.sup.-1.

  20. Sensor for detecting changes in magnetic fields

    DOE Patents [OSTI]

    Praeg, W.F.

    1980-02-26

    A sensor is described for detecting changes in the magnetic field of the equilibrium-field coil of a Tokamak plasma device that comprises a pair of bifilar wires disposed circumferentially, one inside and one outside the equilibrium-field coil. Each is shorted at one end. The difference between the voltages detected at the other ends of the bifilar wires provides a measure of changing flux in the equilibrium-field coil. This difference can be used to detect faults in the coil in time to take action to protect the coil.

  1. Detecting persons concealed in a vehicle

    DOE Patents [OSTI]

    Tucker, Jr., Raymond W.

    2005-03-29

    An improved method for detecting the presence of humans or animals concealed within in a vehicle uses a combination of the continuous wavelet transform and a ratio-based energy calculation to determine whether the motion detected using seismic sensors placed on the vehicle is due to the presence of a heartbeat within the vehicle or is the result of motion caused by external factors such as the wind. The method performs well in the presence of light to moderate ambient wind levels, producing far fewer false alarm indications. The new method significantly improves the range of ambient environmental conditions under which human presence detection systems can reliably operate.

  2. Activated carbon aerogels

    SciTech Connect (OSTI)

    Hanzawa, Y.; Kaneko, K. [Chiba Univ. (Japan)] [Chiba Univ. (Japan); Pekala, R.W. [Lawrence Livermore National Lab., CA (United States)] [Lawrence Livermore National Lab., CA (United States); Dresselhaus, M.S. [Massachusetts Inst. of Technology, Cambridge, MA (United States)] [Massachusetts Inst. of Technology, Cambridge, MA (United States)

    1996-12-25

    Activated carbon aerogels were obtained from the CO{sub 2} activation of the carbon aerogels. The adsorption isotherms of nitrogen on activated carbon aerogels at 77 K were measured and analyzed by the high-resolution {alpha}{sub s} plot to evaluate their porosities. The {alpha}{sub s} plot showed an upward deviation from linearity below {alpha}{sub s} = 0.5, suggesting that the presence of micropores becomes more predominant with the extent of the activation. Activation increased noticeably the pore volume and the surface area (the maximum value: 2600 m{sup 2}.g{sup -1}) without change of the basic network structure of primary particles. Activated carbon aerogels had a bimodal pore size distribution of uniform micropores and mesopores. 16 refs., 2 figs., 1 tab.

  3. Fission signal detection using helium-4 gas fast neutron scintillation detectors

    SciTech Connect (OSTI)

    Lewis, J. M. Kelley, R. P.; Jordan, K. A.; Murer, D.

    2014-07-07

    We demonstrate the unambiguous detection of the fission neutron signal produced in natural uranium during active neutron interrogation using a deuterium-deuterium fusion neutron generator and a high pressure {sup 4}He gas fast neutron scintillation detector. The energy deposition by individual neutrons is quantified, and energy discrimination is used to differentiate the induced fission neutrons from the mono-energetic interrogation neutrons. The detector can discriminate between different incident neutron energies using pulse height discrimination of the slow scintillation component of the elastic scattering interaction between a neutron and the {sup 4}He atom. Energy histograms resulting from this data show the buildup of a detected fission neutron signal at higher energies. The detector is shown here to detect a unique fission neutron signal from a natural uranium sample during active interrogation with a (d, d) neutron generator. This signal path has a direct application to the detection of shielded nuclear material in cargo and air containers. It allows for continuous interrogation and detection while greatly minimizing the potential for false alarms.

  4. Activated recombinant adenovirus proteinases

    DOE Patents [OSTI]

    Anderson, C.W.; Mangel, W.F.

    1999-08-10

    This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described. 29 figs.

  5. Development of Microfluidic Devices Incorporating Electrochemical Detection

    E-Print Network [OSTI]

    Regel, Anne

    2014-05-31

    with electrochemical (EC) detection for the determination of dopamine and nitrite is described. Different fabrication processes were evaluated and optimized to create low cost polymer microchips. A polydimethylsiloxane (PDMS)/glass hybrid microchip capable...

  6. Detecting Air Leaks | Department of Energy

    Office of Environmental Management (EM)

    while a partner observes the house from outside. Large cracks will show up as rays of light. Not a good way to detect small cracks. Shut a door or window on a dollar bill. If...

  7. Spark discharge trace element detection system

    DOE Patents [OSTI]

    Adler-Golden, S.; Bernstein, L.S.; Bien, F.

    1988-08-23

    A spark discharge trace element detection system is provided which includes a spark chamber including a pair of electrodes for receiving a sample of gas to be analyzed at no greater than atmospheric pressure. A voltage is provided across the electrodes for generating a spark in the sample. The intensity of the emitted radiation in at least one primary selected narrow band of the radiation is detected. Each primary band corresponds to an element to be detected in the gas. The intensity of the emission in each detected primary band is integrated during the afterglow time interval of the spark emission and a signal representative of the integrated intensity of the emission in each selected primary bond is utilized to determine the concentration of the corresponding element in the gas. 12 figs.

  8. Detecting cosmic rays of the highest energies

    E-Print Network [OSTI]

    F. Vannucci

    2001-06-06

    Charged cosmic rays have been measured up to macroscopic energies. Concerning neutrinos, the detection is still limited to terrestrial ones (apart from supernova production). A new way to search for extragalactic neutrinos is discussed.

  9. Community Detection from Location-Tagged Networks

    E-Print Network [OSTI]

    Liu, Zhi

    2015-01-01

    Many real world systems or web services can be represented as a network such as social networks and transportation networks. In the past decade, many algorithms have been developed to detect the communities in a network using connections between nodes. However in many real world networks, the locations of nodes have great influence on the community structure. For example, in a social network, more connections are established between geographically proximate users. The impact of locations on community has not been fully investigated by the research literature. In this paper, we propose a community detection method which takes locations of nodes into consideration. The goal is to detect communities with both geographic proximity and network closeness. We analyze the distribution of the distances between connected and unconnected nodes to measure the influence of location on the network structure on two real location-tagged social networks. We propose a method to determine if a location-based community detection...

  10. Detection Methods for Astronomical Time Series

    E-Print Network [OSTI]

    Coehlo, Nathan Kirk

    2010-01-01

    Time Series by Nathan Kirk Coehlo A dissertation submittedCopyright 2010 by Nathan Kirk Coehlo Abstract DetectionTime Series by Nathan Kirk Coehlo Doctor of Philosophy in

  11. Clone Detection in Matlab Simulink Models

    E-Print Network [OSTI]

    of the leading tools for model based software development in the automotive industry. In this thesis a novel.1 Clone Detection Tool Architecture . . . . . . . . . . . . . . . . . 27 5.2 Platform and Tools

  12. Nanofluidic biosensing for beta-amyloid detection 

    E-Print Network [OSTI]

    Chou, I-Hsien

    2009-05-15

    A nanofluidic biosensor using surface-enhanced Raman scattering (SERS) was developed to detect the ?-amyloid (A?) protein, one of the biomarkers of Alzheimer’s disease (AD). Recent studies have indicated that investigating ...

  13. Detection of arcs in automotive electrical systems

    E-Print Network [OSTI]

    Mishrikey, Matthew David

    2005-01-01

    At the present time, there is no established method for the detection of DC electric arcing. This is a concern for forthcoming advanced automotive electrical systems which consist of higher DC electric power bus voltages, ...

  14. Picture Detection in RSVP: Features or Identity?

    E-Print Network [OSTI]

    Potter, Mary C.

    A pictured object can be readily detected in a rapid serial visual presentation sequence when the target is specified by a superordinate category name such as animal or vehicle. Are category features the initial basis for ...

  15. Fast pedestrian detection from a moving vehicle

    E-Print Network [OSTI]

    You, Shuang

    2006-01-01

    This paper presents a method of real-time multi-modal pedestrian detection from a moving vehicle. The system uses both intensity and thermal images captured from cameras mounted at the front of the vehicle to train cascades ...

  16. Detecting open surfaces in three dimensions

    E-Print Network [OSTI]

    Bose, Biswajit, 1981-

    2009-01-01

    We present a novel level-set method for representing and detecting open surfaces embedded in three-dimensional image volumes. Open surfaces are two-dimensional manifolds with a one-dimensional boundary lying within a ...

  17. Exploiting weather forecast data for cloud detection 

    E-Print Network [OSTI]

    Mackie, Shona

    2009-01-01

    Accurate, fast detection of clouds in satellite imagery has many applications, for example Numerical Weather Prediction (NWP) and climate studies of both the atmosphere and of the Earth’s surface temperature. Most ...

  18. Sensor Fault Detection and Isolation System 

    E-Print Network [OSTI]

    Yang, Cheng-Ken

    2014-08-01

    The purpose of this research is to develop a Fault Detection and Isolation (FDI) system which is capable to diagnosis multiple sensor faults in nonlinear cases. In order to lead this study closer to real world applications ...

  19. Selective chemical detection by energy modulation of sensors

    DOE Patents [OSTI]

    Stetter, J.R.; Otagawa, T.

    1991-09-10

    A portable instrument for use in the field in detecting, identifying, and quantifying a component of a sampled fluid includes a sensor which chemically reacts with the component of interest or a derivative thereof, an electrical heating filament for heating the sample before it is applied to the sensor, and modulator for continuously varying the temperature of the filament (and hence the reaction rate) between two values sufficient to produce the chemical reaction. In response to this thermal modulation, the sensor produces a modulated output signal, the modulation of which is a function of the activation energy of the chemical reaction, which activation energy is specific to the particular component of interest and its concentration. Microprocessor which compares the modulated output signal with standard responses for a plurality of components to identify and quantify the particular component of interest. In particular, the concentration of the component of interest is proportional to the amplitude of the modulated output signal, while the identifying activation output energy of the chemical interaction indicative of that component is proportional to a normalized parameter equal to the peak-to-peak amplitude divided by the height of the upper peaks above a base line signal level. 5 figures.

  20. Selective chemical detection by energy modulation of sensors

    DOE Patents [OSTI]

    Stetter, Joseph R. (Naperville, IL); Otagawa, Takaaki (Solon, OH)

    1991-01-01

    A portable instrument for use in the field in detecting, identifying, and quantifying a component of a sampled fluid includes a sensor which chemically reacts with the component of interest or a derivative thereof, an electrical heating filament for heating the sample before it is applied to the sensor, and modulator for continuously varying the temperature of the filament (and hence the reaction rate) between two values sufficient to produce the chemical reaction. In response to this thermal modulation, the sensor produces a modulated output signal, the modulation of which is a function of the activation energy of the chemical reaction, which activation energy is specific to the particular component of interest and its concentration. Microprocessor which compares the modulated output signal with standard responses for a plurality of components to identify and quantify the particular component of interest. In particular, the concentration of the component of interest is proportional to the amplitude of the modulated output signal, while the identifying activation output energy of the chemical interaction indicative of that component is proportional to a normalized parameter equal to the peak-to-peak amplitude divided by the height of the upper peaks above a base line signal level.

  1. Microsoft Word - MDA FINAL FY14 Q1_1_31_14.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    revenues 304,614 260,757 Materials and supplies, at average cost 115,627 112,019 Prepaid expenses 66,976 40,458 Total current assets 1,837,725 1,841,816 Other assets...

  2. Microsoft Word - Q3 MDA 8_11_2015 Update of $172M for Reposting...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to deliver on its mission. BPA also funds regional efforts to protect and enhance fish and wildlife populations affected by hydropower development in the Columbia River...

  3. Tools for MDA Software Development: Evaluation Criteria and Set of Desirable Features

    E-Print Network [OSTI]

    Dascalu, Sergiu

    (PIM), and the Platform Specific Model (PSM) [1]. PIM models the system's functionality, while PSM. The PIM is used for the generation of PSM models, from which can be then generated source code

  4. 2008-10 "Independent Review of the MDA G CME Report by DOE Office...

    Broader source: Energy.gov (indexed) [DOE]

    Deactivation & Decommissioning (D&D) P&RA Community of Practice Facility Engineering Soil & Groundwater Sustainability Program Management Program Management Home Safety Security...

  5. Microsoft Word - MDA FINAL FY14 Q1_1_31_14.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines light on77 PAGE OF PAGESpersonal CERTIFIEDPUB-3140September0 3.

  6. Nuke Watch New Mexico Perspective on MDA G Cap and Cover | Department of

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematicsEnergyInterested Parties -DepartmentAvailable forSite |n t eof Energy

  7. Energy Conservation Standards Activities

    Broader source: Energy.gov (indexed) [DOE]

    Congress August 2014 United States Department of Energy Washington, DC 20585 Energy Conservation Standards Activities Report to Congress | Page i Message from the Assistant...

  8. Low Specific Activity (LSA)

    Broader source: Energy.gov [DOE]

    This scenario provides the planning instructions, guidance, and evaluation forms necessary to conduct an exercise involving a highway shipment of Low Specific Activity (LSA) material.  This...

  9. Alabama Power- UESC Activities

    Broader source: Energy.gov [DOE]

    Presentation—given at the Fall 2012 Federal Utility Partnership Working Group (FUPWG) meeting—discusses Alabama Power and its utility energy service contract (UESC) projects and activities.

  10. Directional detection of galactic dark matter

    E-Print Network [OSTI]

    Mayet, F; Santos, D

    2012-01-01

    Directional detection is a promising Dark Matter search strategy. Taking advantage on the rotation of the Solar system around the galactic center through the Dark Matter halo, it allows to show a direction dependence of WIMP events that may be a powerful tool to identify genuine WIMP events as such. Directional detection strategy requires the simultaneous measurement of the energy and the 3D track of low energy recoils, which is a common challenge for all current projects of directional detectors.

  11. Apparatus and methods for detecting chemical permeation

    DOE Patents [OSTI]

    Vo-Dinh, Tuan (Knoxville, TN)

    1994-01-01

    Apparatus and methods for detecting the permeation of hazardous or toxic chemicals through protective clothing are disclosed. The hazardous or toxic chemicals of interest do not possess the spectral characteristic of luminescence. The apparatus and methods utilize a spectrochemical modification technique to detect the luminescence quenching of an indicator compound which upon permeation of the chemical through the protective clothing, the indicator is exposed to the chemical, thus indicating chemical permeation.

  12. Theoretical prospects for directional WIMP detection

    E-Print Network [OSTI]

    O'Hare, Ciaran A J

    2015-01-01

    Direct detection of dark matter with directional sensitivity is a promising concept for improving the search for weakly interacting massive particles. With information on the direction of WIMP induced nuclear recoils one has access to the full 3-dimensional velocity distribution of the local dark matter halo and thus a potential avenue for studying WIMP astrophysics. Furthermore the unique angular signature of the WIMP recoil distribution provides a crucial discriminant from neutrinos which currently represent the ultimate background to direct detection experiments.

  13. Theoretical prospects for directional WIMP detection

    E-Print Network [OSTI]

    Ciaran A. J. O'Hare

    2015-10-14

    Direct detection of dark matter with directional sensitivity is a promising concept for improving the search for weakly interacting massive particles. With information on the direction of WIMP induced nuclear recoils one has access to the full 3-dimensional velocity distribution of the local dark matter halo and thus a potential avenue for studying WIMP astrophysics. Furthermore the unique angular signature of the WIMP recoil distribution provides a crucial discriminant from neutrinos which currently represent the ultimate background to direct detection experiments.

  14. Cyber Security Audit and Attack Detection Toolkit

    SciTech Connect (OSTI)

    Peterson, Dale

    2012-05-31

    This goal of this project was to develop cyber security audit and attack detection tools for industrial control systems (ICS). Digital Bond developed and released a tool named Bandolier that audits ICS components commonly used in the energy sector against an optimal security configuration. The Portaledge Project developed a capability for the PI Historian, the most widely used Historian in the energy sector, to aggregate security events and detect cyber attacks.

  15. Wireless sensor for detecting explosive material

    DOE Patents [OSTI]

    Lamberti, Vincent E; Howell, Jr., Layton N; Mee, David K; Sepaniak, Michael J

    2014-10-28

    Disclosed is a sensor for detecting explosive devices. The sensor includes a ferromagnetic metal and a molecular recognition reagent coupled to the ferromagnetic metal. The molecular recognition reagent is operable to expand upon absorption of vapor from an explosive material such that the molecular recognition reagent changes a tensile stress upon the ferromagnetic metal. The explosive device is detected based on changes in the magnetic switching characteristics of the ferromagnetic metal caused by the tensile stress.

  16. Video motion detection for physical security applications

    SciTech Connect (OSTI)

    Matter, J.C.

    1990-01-01

    Physical security specialists have been attracted to the concept of video motion detection for several years. Claimed potential advantages included additional benefit from existing video surveillance systems, automatic detection, improved performance compared to human observers, and cost effectiveness. In recent years significant advances in image processing dedicated hardware and image analysis algorithms and software have accelerated the successful application of video motion detection systems to a variety of physical security applications. Currently Sandia is developing several advanced systems that employ image processing techniques for a broader set of safeguards and security applications. TCATS (Target Cueing and Tracking System) uses a set of powerful, flexible, modular algorithms and software to alarm on purposeful target motion. Custom TCATS hardware optimized for perimeter security applications is currently being evaluated with video input. VISDTA (Video Imaging System for Detection, Tracking, and Assessment) uses some of the same TCATS algorithms and operates with a thermal imager input. In the scan mode, VISDTA detects changes in a scene from the previous image at a given scan point; in the stare mode, VISDTA detects purposeful motion similar to TCATS.

  17. Image Change Detection via Ensemble Learning

    SciTech Connect (OSTI)

    Martin, Benjamin W [ORNL] [ORNL; Vatsavai, Raju [ORNL] [ORNL

    2013-01-01

    The concept of geographic change detection is relevant in many areas. Changes in geography can reveal much information about a particular location. For example, analysis of changes in geography can identify regions of population growth, change in land use, and potential environmental disturbance. A common way to perform change detection is to use a simple method such as differencing to detect regions of change. Though these techniques are simple, often the application of these techniques is very limited. Recently, use of machine learning methods such as neural networks for change detection has been explored with great success. In this work, we explore the use of ensemble learning methodologies for detecting changes in bitemporal synthetic aperture radar (SAR) images. Ensemble learning uses a collection of weak machine learning classifiers to create a stronger classifier which has higher accuracy than the individual classifiers in the ensemble. The strength of the ensemble lies in the fact that the individual classifiers in the ensemble create a mixture of experts in which the final classification made by the ensemble classifier is calculated from the outputs of the individual classifiers. Our methodology leverages this aspect of ensemble learning by training collections of weak decision tree based classifiers to identify regions of change in SAR images collected of a region in the Staten Island, New York area during Hurricane Sandy. Preliminary studies show that the ensemble method has approximately 11.5% higher change detection accuracy than an individual classifier.

  18. Novel methods for detecting buried explosive devices

    SciTech Connect (OSTI)

    Kercel, S.W.; Burlage, R.S.; Patek, D.R.; Smith, C.M.; Hibbs, A.D.; Rayner, T.J.

    1997-04-01

    Oak Ridge National Laboratory (ORNL) and Quantum Magnetics, Inc. (QM) are exploring novel landmine detection technologies. Technologies considered here include bioreporter bacteria, swept acoustic resonance, nuclear quadrupole resonance (NQR), and semiotic data fusion. Bioreporter bacteria look promising for third-world humanitarian applications; they are inexpensive, and deployment does not require high-tech methods. Swept acoustic resonance may be a useful adjunct to magnetometers in humanitarian demining. For military demining, NQR is a promising method for detecting explosive substances; of 50,000 substances that have been tested, none has an NQR signature that can be mistaken for RDX or TNT. For both military and commercial demining, sensor fusion entails two daunting tasks, identifying fusible features in both present-day and emerging technologies, and devising a fusion algorithm that runs in real-time on cheap hardware. Preliminary research in these areas is encouraging. A bioreporter bacterium for TNT detection is under development. Investigation has just started in swept acoustic resonance as an approach to a cheap mine detector for humanitarian use. Real-time wavelet processing appears to be a key to extending NQR bomb detection into mine detection, including TNT-based mines. Recent discoveries in semiotics may be the breakthrough that will lead to a robust fused detection scheme.

  19. Electrochemical detection of leukemia oncogenes using enzyme-loaded carbon nanotube labels

    SciTech Connect (OSTI)

    Lee, Ai Cheng; Du, Dan; Chen, Baowei; Heng, Chew-Kiat; Lim, Tit-Meng; Lin, Yuehe

    2014-09-07

    Here we describe an ultrasensitive electrochemical nucleic acids assay amplified by carbon nanotubes (CNTs)-based labels for the detection of human acute lymphocytic leukemia (ALL) related p185 BCR-ABL fusion transcript. The carboxylated CNTs were functionalized with horseradish peroxidase (HRP) molecules and target-specific detection probes (DP) via diimide-activated amidation, and used to label and amplify target hybridization signal. The activity of captured HRP was monitored by square-wave voltammetry measuring the electroactive enzymatic product in the presence of 2-aminophenol and hydrogen peroxide substrate solution. The effect of DP and HRP loading of the CNT-based labels on its signal-to-noise ratio of electrochemical detection was studied systematically for the first time. Under optimized conditions, the signal-amplified assay achieved a detection limit of 83 fM targets oligonuecleotides and a 4-order wide dynamic range of target concentration. The resulting assay allowed a robust discrimination between the perfect match and a three-base mismatch sequence. When subjected to full-length (491 bp) DNA oncogene, the approach demonstrated a detection limit of approximately 33 pg of the target gene. The high sensitivity and specificity of assay enabled PCR-free detection of target transcripts in as little as 65 ng of mRNA extracted from positive ALL cell lines SUP-B15, in comparison to those obtained from negative cell lines HL-60. The approach holds promise for simple, low cost and ultrasensitive electrochemical nucleic acids detection in portable devices, point-of-care and early disease diagnostic applications.

  20. Aging assessment for active fire protection systems

    SciTech Connect (OSTI)

    Ross, S.B. [Science and Engineering Associates, Inc. (United States); Nowlen, S.P.; Tanaka, T. [Sandia National Labs., Albuquerque, NM (United States)

    1995-06-01

    This study assessed the impact of aging on the performance and reliability of active fire protection systems including both fixed fire suppression and fixed fire detection systems. The experience base shows that most nuclear power plants have an aggressive maintenance and testing program and are finding degraded fire protection system components before a failure occurs. Also, from the data reviewed it is clear that the risk impact of fire protection system aging is low. However, it is assumed that a more aggressive maintenance and testing program involving preventive diagnostics may reduce the risk impact even further.

  1. Design and Fabrication of Cherenkov Counters for the Detection of SNM

    SciTech Connect (OSTI)

    Erickson, Anna S.; Lanza, Richard; Galaitsis, Anthony; Hynes, Michael; Blackburn, Brandon; Bernstein, Adam

    2011-12-13

    The need for large-size detectors for long-range active interrogation (AI) detection of SNM has generated interest in water-based detector technologies. Water Cherenkov Detectors (WCD) were selected for this research because of their transportability, scalability, and an inherent energy threshold. The detector design and analysis was completed using the Geant4 toolkit. It was demonstrated both computationally and experimentally that it is possible to use WCD to detect and characterize gamma rays. Absolute efficiency of the detector (with no energy cuts applied) was determined to be around 30% for a {sup 60}Co source.

  2. Time Activity Time Activity Time Activity Tuesday CLOSED CONFERENCE CLOSED CONFERENCE CLOSED CONFERENCE

    E-Print Network [OSTI]

    Burg, Theresa

    Time Activity Time Activity Time Activity Tuesday CLOSED CONFERENCE CLOSED CONFERENCE CLOSED CONFERENCE 2-Jun-15 Wednesday CLOSED CONFERENCE CLOSED CONFERENCE CLOSED CONFERENCE 3-Jun-15 Thursday CLOSED

  3. Activation of fly ash

    DOE Patents [OSTI]

    Corbin, David R. (New Castle, DE); Velenyi, Louis J. (Lyndhurst, OH); Pepera, Marc A. (Northfield, OH); Dolhyj, Serge R. (Parma, OH)

    1986-01-01

    Fly ash is activated by heating a screened magnetic fraction of the ash in a steam atmosphere and then reducing, oxidizing and again reducing the hydrothermally treated fraction. The activated fly ash can be used as a carbon monoxide disproportionating catalyst useful in the production of hydrogen and methane.

  4. Activation of fly ash

    DOE Patents [OSTI]

    Corbin, D.R.; Velenyi, L.J.; Pepera, M.A.; Dolhyj, S.R.

    1986-08-19

    Fly ash is activated by heating a screened magnetic fraction of the ash in a steam atmosphere and then reducing, oxidizing and again reducing the hydrothermally treated fraction. The activated fly ash can be used as a carbon monoxide disproportionating catalyst useful in the production of hydrogen and methane.

  5. Detection of circular polarization in light scattered from photosynthetic microbes

    E-Print Network [OSTI]

    Sparks, William B; Germer, Thomas A; Chen, Feng; DasSarma, Shiladitya; DasSarma, Priya; Robb, Frank T; Manset, Nadine; Kolokolova, Ludmilla; Reid, Neill; Macchetto, F Duccio; Martin, William; 10.1073/pnas.0810215106

    2009-01-01

    The identification of a universal biosignature that could be sensed remotely is critical to the prospects for success in the search for life elsewhere in the universe. A candidate universal biosignature is homochirality, which is likely to be a generic property of all biochemical life. Due to the optical activity of chiral molecules, it has been hypothesized that this unique characteristic may provide a suitable remote sensing probe using circular polarization spectroscopy. Here, we report the detection of circular polarization in light scattered by photosynthetic microbes. We show that the circular polarization appears to arise from circular dichroism of the strong electronic transitions of photosynthetic absorption bands. We conclude that circular polarization spectroscopy could provide a powerful remote sensing technique for generic life searches.

  6. Photon Detection System Designs for the Deep Underground Neutrino Experiment

    E-Print Network [OSTI]

    Whittington, Denver

    2015-01-01

    The Deep Underground Neutrino Experiment (DUNE) will be a premier facility for exploring long-standing questions about the boundaries of the standard model. Acting in concert with the liquid argon time projection chambers underpinning the far detector design, the DUNE photon detection system will capture ultraviolet scintillation light in order to provide valuable timing information for event reconstruction. To maximize the active area while maintaining a small photocathode coverage, the experiment will utilize a design based on plastic light guides coated with a wavelength-shifting compound, along with silicon photomultipliers, to collect and record scintillation light from liquid argon. This report presents recent preliminary performance measurements of this baseline design and several alternative designs which promise significant improvements in sensitivity to low-energy interactions.

  7. FY2010 Annual Report for the Actinide Isomer Detection Project

    SciTech Connect (OSTI)

    Warren, Glen A.; Francy, Christopher J.; Ressler, Jennifer J.; Erikson, Luke E.; Miller, Erin A.; Hatarik, R.

    2011-01-01

    This project seeks to identify a new signature for actinide element detection in active interrogation. This technique works by exciting and identifying long-lived nuclear excited states (isomers) in the actinide isotopes and/or primary fission products. Observation of isomers in the fission products will provide a signature for fissile material. For the actinide isomers, the decay time and energy of the isomeric state is unique to a particular isotope, providing an unambiguous signature for Special Nuclear Materials (SNM). Future work will include a follow-up measurement scheduled for December 2010 at LBNL. Lessons learned from the July 2010 measurements will be incorporated into these new measurements. Analysis of both the July and December experiments will be completed in a few months. A research paper to be submitted to a peer-reviewed journal will be drafted if the conclusions from the measurements warrant publication.

  8. Recognizing Human Activities from Multi-Modal Shu Chen,Yan Huang

    E-Print Network [OSTI]

    Huang, Yan

    and used in our experiments can also be accessed online. II. RELATED WORK Automatic human activities and experiments are not provided in their paper. Joshua et al. [5] use RFID-based tech- niques to detect humanRecognizing Human Activities from Multi-Modal Sensors Shu Chen,Yan Huang Department of Computer

  9. Neutron counter based on beryllium activation

    SciTech Connect (OSTI)

    Bienkowska, B.; Prokopowicz, R.; Kaczmarczyk, J.; Paducha, M. [Institute of Plasma Physics and Laser Microfusion (IPPLM), Hery 23, 01-497 Warsaw (Poland); Scholz, M.; Igielski, A. [Institute of Nuclear Physics PAS (IFJPAN), Radzikowskiego 152, 31-342 Krakow (Poland); Karpinski, L. [Faculty of Electrical Engineering, Rzeszow University of Technology, Pola 2, 35-959 Rzeszow (Poland); Pytel, K. [National Centre for Nuclear Research (NCBJ), Soltana 7, 05-400 Otwock - Swierk (Poland)

    2014-08-21

    The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction {sup 9}Be(n, ?){sup 6}He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, {sup 6}He, decays with half-life T{sub 1/2} = 0.807 s emitting ?{sup ?} particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of ?–particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known ?–source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5–the Monte Carlo transport code. It allowed proper application of the results of transport calculations of ?{sup ?} particles emitted from radioactive {sup 6}He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

  10. Detecting Fractures Using Technology at High Temperatures and...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Detecting Fractures Using Technology at High Temperatures and Depths - Geothermal Ultrasonic Fracture Imager (GUFI); 2010 Geothermal Technology Program Peer Review Report Detecting...

  11. Nuclear Detection and Sensor Testing Center | Y-12 National Security...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Detection and Sensor Testing Center, which offers dedicated facilities for the testing of radiation detection capabilities using enriched and highly enriched uranium. In addition...

  12. Damage Detection in Plate Structures using Guided Ultrasonic Waves

    E-Print Network [OSTI]

    Jarmer, Gregory James Sylvester

    2009. “Evaluation of the Damage Detection Capability of alikelihood Estimation of Damage Location in Guided- waveStatistically-based Damage Detection in Geometrically-

  13. Fast Change Point Detection for Electricity Market Analysis

    E-Print Network [OSTI]

    Gu, William

    2014-01-01

    The trouble with electricity markets: understandingPoint Detection for Electricity Market Analysis William Gu ?Point Detection for Electricity Market Analysis William Gu,

  14. EECBG Success Story: Energy Detectives Help Pennsylvania Town...

    Energy Savers [EERE]

    Energy Detectives Help Pennsylvania Town Reduce Costs EECBG Success Story: Energy Detectives Help Pennsylvania Town Reduce Costs July 23, 2010 - 3:24pm Addthis Judith Mondre meets...

  15. Detection and characterization of multi-filament evolution during...

    Office of Scientific and Technical Information (OSTI)

    Journal Article: Detection and characterization of multi-filament evolution during resistive switching. Citation Details In-Document Search Title: Detection and characterization of...

  16. A different Big Bang theory: Los Alamos unveils explosives detection...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    unveils explosives detection expertise A different Big Bang theory: Los Alamos unveils explosives detection expertise A team of scientists is now rolling out a collaborative...

  17. Automatic Microaneurysm Detection and Characterization Through Digital Color Fundus Images

    E-Print Network [OSTI]

    Martins, Charles

    2010-01-01

    and M. D. Abr` moff. Automatic detection of red a lesions inAutomatic Microaneurysm Detection and Characterizationimportant task in the automatic MAs characterization scheme.

  18. Prospects for Relic Neutrino Detection at PTOLEMY: Princeton...

    Office of Environmental Management (EM)

    Relic Neutrino Detection at PTOLEMY: Princeton Tritium Observatory for Light, Early-Universe, Massive-Neutrino Yield Prospects for Relic Neutrino Detection at PTOLEMY: Princeton...

  19. Multiscale Edge Detection in the Corona

    E-Print Network [OSTI]

    C. Alex Young; Peter T. Gallagher

    2008-04-11

    Coronal Mass Ejections (CMEs) are challenging objects to detect using automated techniques, due to their high velocity and diffuse, irregular morphology. A necessary step to automating the detection process is to first remove the subjectivity introduced by the observer used in the current, standard, CME detection and tracking method. Here we describe and demonstrate a multiscale edge detection technique that addresses this step and could serve as one part of an automated CME detection system. This method provides a way to objectively define a CME front with associated error estimates. These fronts can then be used to extract CME morphology and kinematics. We apply this technique to a CME observed on 18 April 2000 by the Large Angle Solar COronagraph experiment (LASCO) C2/C3 and a CME observed on 21 April 2002 by LASCO C2/C3 and the Transition Region and Coronal Explorer (TRACE). For the two examples in this work, the heights determined by the standard manual method are larger than those determined with the multiscale method by approximately 10% using LASCO data and approximately 20% using TRACE data.

  20. Active optical zoom system

    DOE Patents [OSTI]

    Wick, David V.

    2005-12-20

    An active optical zoom system changes the magnification (or effective focal length) of an optical imaging system by utilizing two or more active optics in a conventional optical system. The system can create relatively large changes in system magnification with very small changes in the focal lengths of individual active elements by leveraging the optical power of the conventional optical elements (e.g., passive lenses and mirrors) surrounding the active optics. The active optics serve primarily as variable focal-length lenses or mirrors, although adding other aberrations enables increased utility. The active optics can either be LC SLMs, used in a transmissive optical zoom system, or DMs, used in a reflective optical zoom system. By appropriately designing the optical system, the variable focal-length lenses or mirrors can provide the flexibility necessary to change the overall system focal length (i.e., effective focal length), and therefore magnification, that is normally accomplished with mechanical motion in conventional zoom lenses. The active optics can provide additional flexibility by allowing magnification to occur anywhere within the FOV of the system, not just on-axis as in a conventional system.

  1. Structural damage detection using the holder exponent.

    SciTech Connect (OSTI)

    Farrar, C. R. (Charles R.); Do, N. B. (Nguyen B.); Green, S. R. (Scott R.); Schwartz, T. A. (Timothy A.)

    2002-01-01

    This paper implements a damage detection strategy that identifies damage sensitive features associated with nonlinearities. Some rion-linezlrities result from discontinuities introduced into the data by certain types of darnage. These discontinuities may also result from noise in the measured dynamic response data or can be caused by random excitation of the system. The Holder Exponent, which is a measure of the degree to which a signal is differentiable, is used to detect the discontinuities. By studying the Holder bponent as a function af time, a statistical model is developed that classifies changes in the Holder Exponent that are associated with clamage-induced discontinuities. The results show that for certain cases, the Holder Exponent is an effective technique to detect damage.

  2. Probe for contamination detection in recyclable materials

    DOE Patents [OSTI]

    Taleyarkhan, Rusi

    2003-08-05

    A neutron detection system for detection of contaminants contained within a bulk material during recycling includes at least one neutron generator for neutron bombardment of the bulk material, and at least one gamma ray detector for detection of gamma rays emitted by contaminants within the bulk material. A structure for analyzing gamma ray data is communicably connected to the gamma ray detector, the structure for analyzing gamma ray data adapted. The identity and concentration of contaminants in a bulk material can also be determined. By scanning the neutron beam, discrete locations within the bulk material having contaminants can be identified. A method for recycling bulk material having unknown levels of contaminants includes the steps of providing at least one neutron generator, at least one gamma ray detector, and structure for analyzing gamma ray data, irradiating the bulk material with neutrons, and then determining the presence of at least one contaminant in the bulk material from gamma rays emitted from the bulk material.

  3. Disentangling Dark Matter Dynamics with Directional Detection

    SciTech Connect (OSTI)

    Lisanti, Mariangela; Wacker, Jay G.; /SLAC

    2009-12-16

    Inelastic dark matter reconciles the DAMA anomaly with other null direct detection experiments and points to a non-minimal structure in the dark matter sector. In addition to the dominant inelastic interaction, dark matter scattering may have a subdominant elastic component. If these elastic interactions are suppressed at low momentum transfer, they will have similar nuclear recoil spectra to inelastic scattering events. While upcoming direct detection experiments will see strong signals from such models, they may not be able to unambiguously determine the presence of the subdominant elastic scattering from the recoil spectra alone. We show that directional detection experiments can separate elastic and inelastic scattering events and discover the underlying dynamics of dark matter models.

  4. Network Community Detection on Metric Space

    E-Print Network [OSTI]

    Saha, Suman

    2015-01-01

    Community detection in a complex network is an important problem of much interest in recent years. In general, a community detection algorithm chooses an objective function and captures the communities of the network by optimizing the objective function, and then, one uses various heuristics to solve the optimization problem to extract the interesting communities for the user. In this article, we demonstrate the procedure to transform a graph into points of a metric space and develop the methods of community detection with the help of a metric defined for a pair of points. We have also studied and analyzed the community structure of the network therein. The results obtained with our approach are very competitive with most of the well-known algorithms in the literature, and this is justified over the large collection of datasets. On the other hand, it can be observed that time taken by our algorithm is quite less compared to other methods and justifies the theoretical findings.

  5. Renewable Surface Biosensors With Optical Detection

    SciTech Connect (OSTI)

    Bruckner-Lea, Cynthia J.; Ackerman, Eric J.; Dockendorff, Brian P.; Holman, David A.; Grate, Jay W.

    2001-12-01

    One major challenge in the development of biosensors is the limited lifetime of a chemically selective surface that includes biomolecules. Renewable surface biosensors address this issue by using fresh aliquots of derivatized microbeads for each analysis. The analyte detection can then occur on the microbeads, or downstream from the microbeads. In this paper, we will describe two types of renewable surface biosensors. The first renewable biosensor system includes on-column optical detection for monitoring the binding of biomolecules onto protein or DNA-derivatized Sepharose beads. The second renewable biosensor system includes detection downstream from the microparticles and is based on the use of derivatized magnetic particles for selective binding. The magnetic particles are fluidically captured and released in a sequential injection system to allow the automation of an Enzyme Linked ImmunoSorbent Assay.

  6. Renewable Surface Biosensors with Optical Detection

    SciTech Connect (OSTI)

    Bruckner-Lea, Cindy J.; Ackerman, Eric J.; Dockendorff, Brian P.; Holman, David A.; Grate, Jay W.

    2001-04-30

    One major challenge in the development of biosensors is the limited lifetime of a chemically selective surface that includes biomolecules. Renewable surface biosensors address this issue by using fresh aliquots of derivatized microbeads for each analysis. The analyte detection can then occur on the microbeads, or downstream from the microbeads. In this paper, we will describe two types of renewable surface biosensors. The first renewable biosensor system includes on-column optical detection for monitoring the binding of biomolecules onto protein or DNA-derivatized Sepharose beads. The second renewable biosensor system includes detection downstream from the microparticles and is based on the use of derivatized magnetic particles for selective binding. The magnetic particles are fluidically captured and released in a sequential injection system to allow the automation of an Enzyme Linked ImmunoSorbent Assay.

  7. A toolkit for detecting technical surprise.

    SciTech Connect (OSTI)

    Trahan, Michael Wayne; Foehse, Mark C.

    2010-10-01

    The detection of a scientific or technological surprise within a secretive country or institute is very difficult. The ability to detect such surprises would allow analysts to identify the capabilities that could be a military or economic threat to national security. Sandia's current approach utilizing ThreatView has been successful in revealing potential technological surprises. However, as data sets become larger, it becomes critical to use algorithms as filters along with the visualization environments. Our two-year LDRD had two primary goals. First, we developed a tool, a Self-Organizing Map (SOM), to extend ThreatView and improve our understanding of the issues involved in working with textual data sets. Second, we developed a toolkit for detecting indicators of technical surprise in textual data sets. Our toolkit has been successfully used to perform technology assessments for the Science & Technology Intelligence (S&TI) program.

  8. Neutrino detection at a spallation source

    E-Print Network [OSTI]

    Huang, Ming-Yang

    2015-01-01

    In this paper, we study the detection of accelerator neutrinos and supernova (SN) neutrinos at China Spallation Neutron Source (CSNS). Firstly, by using the code FLUKA, the processes of accelerator neutrinos production during the proton beam hitting on the tungsten target can be simulated, and the yield efficiency, numerical flux, average energy of different flavor neutrinos are given. Secondly, the detection of accelerator neutrinos through two reaction channels: the neutrino-electron reactions and the neutrino-carbon reactions, is studied, and the neutrino event numbers can be calculated. Finally, while considering the SN shock effects, the MSW effects, the neutrino collective effects, and the Earth matter effects, the detection of SN neutrinos on the Earth is studied. Then, the event numbers of SN neutrinos observed through various reaction channels are given.

  9. Nuclear material detection apparatus and method

    DOE Patents [OSTI]

    Jones, James L.; Hoggan, Jerry M.; Harker, Yale D.; Yoon, Woo Y.; Johnson, Larry O.

    2006-11-28

    A device for detecting photonuclear-induced neutrons is described herein. One embodiment of the device may comprise a neutron detector and a detection circuit. The neutron detector may comprise a detector output. The detection circuit may be operatively connected to the detector output and may comprise an amplifier, a low-pass filter, and a high pass filter. The amplifier may comprise an amplifier input and an amplifier output. The amplifier input may be being operatively connected to the detector output. The low-pass filter may comprise a low-pass filter input and a low-pass filter output. The low-pass filter input may be operatively connected to the amplifier output. The high-pass filter may comprise a high-pass filter input and a high-pass filter output. The high-pass filter input may be operatively connected to the amplifier output.

  10. System and method for detecting cells or components thereof

    DOE Patents [OSTI]

    Porter, Marc D. (Ames, IA); Lipert, Robert J. (Ames, IA); Doyle, Robert T. (Ames, IA); Grubisha, Desiree S. (Corona, CA); Rahman, Salma (Ames, IA)

    2009-01-06

    A system and method for detecting a detectably labeled cell or component thereof in a sample comprising one or more cells or components thereof, at least one cell or component thereof of which is detectably labeled with at least two detectable labels. In one embodiment, the method comprises: (i) introducing the sample into one or more flow cells of a flow cytometer, (ii) irradiating the sample with one or more light sources that are absorbed by the at least two detectable labels, the absorption of which is to be detected, and (iii) detecting simultaneously the absorption of light by the at least two detectable labels on the detectably labeled cell or component thereof with an array of photomultiplier tubes, which are operably linked to two or more filters that selectively transmit detectable emissions from the at least two detectable labels.

  11. VOICE ACTIVITY DETECTION IN THE PRESENCE OF BREATHING NOISE USING NEURAL NETWORK AND HIDDEN MARKOV MODEL

    E-Print Network [OSTI]

    Virtanen, Tuomas

    MODEL Mikko Myllym¨aki and Tuomas Virtanen Department of Signal Processing, Tampere University of Technology Korkeakoulunkatu 1, 33720, Tampere, Finland email: mikko.v.myllymaki@tut.fi, tuomas

  12. Hypothesis Testing Framework for Active Object Detection Nikolay Atanasov*, Bharath Sankaran*,

    E-Print Network [OSTI]

    Daniilidis, Kostas

    and orientation. The sensor then plans a sequence of view- points, which balances the amount of energy used restricted to controlled industrial environments. The focus has shifted to high-level interactive tasks, {atanasov, pappasg}@seas.upenn.edu. B. Sankaran is with the Computational Learning and Motor Con- trol Lab

  13. A Novel Technique for Improving Hardware Trojan Detection and Reducing Trojan Activation Time

    E-Print Network [OSTI]

    Plusquellic, James

    to disclose Trojan impact on design characteristics beyond process and environmental variations. Trojan,tehrani}@engr.uconn.edu Jim Plusquellic ECE Department University of New Mexico jimp@ece.unm.edu Abstract-- Fabless by nets with low transition probabilities to lessen its impact on circuit side-channel signals

  14. Detecting Bots Based on Keylogging Activities Yousof Al-Hammadi and Uwe Aickelin

    E-Print Network [OSTI]

    Aickelin, Uwe

    . Index Terms­ API function calls, Bot, Correlation, IRC I. INTRODUCTION For some time now, computers face (IRC) network as a communication channel. These instructions command the bot on the infected machine connects to the IRC server and joins the specified Command and Control channel. Having joined the channel

  15. Real-time Storm Detection and Weather Forecast Activation through Data Mining and Events Processing

    E-Print Network [OSTI]

    Plale, Beth

    in the physical environment driven by the use cases in mesoscale meteorology. The contribution of the research

  16. Detecting stable phase structures in EEG signals to classify brain activity amplitude patterns

    E-Print Network [OSTI]

    Ruiz, Yusely; Li, Guang; Freeman, Walter J III; Gonzalez, Eduardo

    2009-01-01

    Freeman, W. J. and Van Dijk, B. W. , 1987. "Spatial patternsBreakspear M, Cappellen A. Dijk B. W. , 2003. ?Nonlinearphase (PM) (Freeman and Van Dijk 1987; Freeman and Barrie

  17. Rapid detection of thrombin and other protease activity directly in whole blood

    E-Print Network [OSTI]

    Yu, Johnson Chung Sing

    2012-01-01

    an environment without wall power, say out in the field of ain a POC setting without wall power. According to Figure 17

  18. Nanogenerator as an active sensor for vortex capture and ambient wind-velocity detection

    E-Print Network [OSTI]

    Wang, Zhong L.

    efficiently convert the vortex motion in the atmosphere into electricity. Based on the Karman vortex street in wireless environmental monitoring networks. 1. Introduction Self-powered nanosystem is a promising concept for the realization of environmental wireless sensor networks. Due to the enormous demands of distributed nodes

  19. On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells

    E-Print Network [OSTI]

    Song, Qing

    The frequencies of antigen-specific CD4+ T cells in samples of human tissue have been difficult to determine accurately ex vivo, particularly for autoimmune diseases such as multiple sclerosis or type 1 diabetes. Conventional ...

  20. Passive Acoustic Detection of Wind Turbine In-Flow Conditions for Active Control and Optimization

    SciTech Connect (OSTI)

    Murray, Nathan E.

    2012-03-12

    Wind is a significant source of energy; however, the human capability to produce electrical energy still has many hurdles to overcome. One of these is the unpredictability of the winds in the atmospheric boundary layer (ABL). The ABL is highly turbulent in both stable and unstable conditions (based on the vertical temperature profile) and the resulting fluctuations can have a dramatic impact on wind turbine operation. Any method by which these fluctuations could be observed, estimated, or predicted could provide a benefit to the wind energy industry as a whole. Based on the fundamental coupling of velocity fluctuations to pressure fluctuations in the nearly incompressible flow in the ABL, This work hypothesizes that a ground-based array of infrasonic pressure transducers could be employed to estimate the vertical wind profile over a height relevant for wind turbines. To analyze this hypothesis, experiments and field deployments were conducted. Wind tunnel experiments were performed for a thick turbulent boundary layer over a neutral or heated surface. Surface pressure and velocity probe measurements were acquired simultaneously. Two field deployments yielded surface pressure data from a 49 element array. The second deployment at the Reese Technology Center in Lubbock, TX, also included data from a smaller aperture, 96-element array and a 200-meter tall meteorological tower. Analysis of the data successfully demonstrated the ability to estimate the vertical velocity profile using coherence data from the pressure array. Also, dynamical systems analysis methods were successful in identifying and tracking a gust type event. In addition to the passive acoustic profiling method, this program also investigated a rapid response Doppler SODAR system, the optimization of wind turbine blades for enhanced power with reduced aeroacoustic noise production, and the implementation of a wireless health monitoring system for the wind turbine blades. Each of these other objectives was met successfully. The use of phase unwrapping applied to SODAR data was found to yield reasonable results for per-pulse measurements. A health monitoring system design analysis was able to demonstrate the ability to use a very small number of sensors to monitor blade health based on the blade's overall structural modes. Most notable was the development of a multi-objective optimization methodology that successfully yielded an aerodynamic blade design that produces greater power output with reduced aerodynamic loading noise. This optimization method could be significant for future design work.

  1. An active system for the detection of special fissile material in small watercraft 

    E-Print Network [OSTI]

    Johansen, Norman Alfan, III

    2006-10-30

    technique. The MCNP Monte Carlo transport code was used to simulate the use of a pulsed neutron generator to induce fission in the fissile material and then estimate the detector response. The detector modeled was based on elastic scattering-induced recoil...

  2. Adaptation of an enzyme-linked immunosorbent assay for detecting Brucella antibody activity in reindeer sera 

    E-Print Network [OSTI]

    Perry, Dana Lynn

    1982-01-01

    compared to conventional serologic results from the SPT, card, Rivanol, and CF methods. Sera were considered pos1tive by the SPT, Rivanol, and CF methods according to the criteria of a SPTA ' 50, SPTB '100, Rivanol '50, Hill's CF &40, and automated CF...lar manifestations 1n cattle (6), elk (7), and reindeer (8). Signs of infection 1n female animals include abortion, retained placentae, and birth of nonv1able offspring; signs in males include inflammation of the seminal vesicules, ampullae, test1...

  3. Comparison of methods for melt detection over Greenland using active and passive microwave measurements

    E-Print Network [OSTI]

    Long, David G.

    snow absorbs approximately 45% more incoming solar radiation than dry snow (Abdalati and Steffen, 1995/sensor combinations are compared using data for the summer of 2000. The sensors include the Special Spectral Microwave factor in global sea level change, the Earth's radiation budget, and other areas of global environmental

  4. Design and evaluation of the ReKon : an integrated detection and assessment perimeter system.

    SciTech Connect (OSTI)

    Dabling, Jeffrey Glenn; Andersen, Jason Jann; McLaughlin, James O.

    2013-02-01

    Kontek Industries (Kannapolis, NC) and their subsidiary, Stonewater Control Systems (Kannapolis, NC), have entered into a cooperative research and development agreement with Sandia to jointly develop and evaluate an integrated perimeter security system solution, one that couples access delay with detection and assessment. This novel perimeter solution was designed to be configurable for use at facilities ranging from high-security military sites to commercial power plants, to petro/chemical facilities of various kinds. A prototype section of the perimeter has been produced and installed at the Sandia Test and Evaluation Center in Albuquerque, NM. This prototype system integrated fiber optic break sensors, active infrared sensors, fence disturbance sensors, video motion detection, and ground sensors. This report documents the design, testing, and performance evaluation of the developed ReKon system. The ability of the system to properly detect pedestrian or vehicle attempts to bypass, breach, or otherwise defeat the system is characterized, as well as the Nuisance Alarm Rate.

  5. DETECTING INDUSTRIAL POLLUTION IN THE ATMOSPHERES OF EARTH-LIKE EXOPLANETS

    SciTech Connect (OSTI)

    Lin, Henry W. [Harvard College, Cambridge, MA 02138 (United States); Abad, Gonzalo Gonzalez; Loeb, Abraham, E-mail: henrylin@college.harvard.edu, E-mail: ggonzalezabad@cfa.harvard.edu, E-mail: aloeb@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States)

    2014-09-01

    Detecting biosignatures, such as molecular oxygen in combination with a reducing gas, in the atmospheres of transiting exoplanets has been a major focus in the search for alien life. We point out that in addition to these generic indicators, anthropogenic pollution could be used as a novel biosignature for intelligent life. To this end, we identify pollutants in the Earth's atmosphere that have significant absorption features in the spectral range covered by the James Webb Space Telescope. We focus on tetrafluoromethane (CF{sub 4}) and trichlorofluoromethane (CCl{sub 3}F), which are the easiest to detect chlorofluorocarbons (CFCs) produced by anthropogenic activity. We estimate that ?1.2 days (?1.7 days) of total integration time will be sufficient to detect or constrain the concentration of CCl{sub 3}F (CF{sub 4}) to ?10 times the current terrestrial level.

  6. Detecting particles with cell phones: the Distributed Electronic Cosmic-ray Observatory

    E-Print Network [OSTI]

    Vandenbroucke, Justin; Karn, Peter; Meehan, Matthew; Plewa, Matthew; Ruggles, Tyler; Schultz, David; Peacock, Jeffrey; Simons, Ariel Levi

    2015-01-01

    In 2014 the number of active cell phones worldwide for the first time surpassed the number of humans. Cell phone camera quality and onboard processing power (both CPU and GPU) continue to improve rapidly. In addition to their primary purpose of detecting photons, camera image sensors on cell phones and other ubiquitous devices such as tablets, laptops and digital cameras can detect ionizing radiation produced by cosmic rays and radioactive decays. While cosmic rays have long been understood and characterized as a nuisance in astronomical cameras, they can also be identified as a signal in idle camera image sensors. We present the Distributed Electronic Cosmic-ray Observatory (DECO), a platform for outreach and education as well as for citizen science. Consisting of an app and associated database and web site, DECO harnesses the power of distributed camera image sensors for cosmic-ray detection.

  7. Detecting particles with cell phones: the Distributed Electronic Cosmic-ray Observatory

    E-Print Network [OSTI]

    Justin Vandenbroucke; Silvia Bravo; Peter Karn; Matthew Meehan; Matthew Plewa; Tyler Ruggles; David Schultz; Jeffrey Peacock; Ariel Levi Simons

    2015-10-26

    In 2014 the number of active cell phones worldwide for the first time surpassed the number of humans. Cell phone camera quality and onboard processing power (both CPU and GPU) continue to improve rapidly. In addition to their primary purpose of detecting photons, camera image sensors on cell phones and other ubiquitous devices such as tablets, laptops and digital cameras can detect ionizing radiation produced by cosmic rays and radioactive decays. While cosmic rays have long been understood and characterized as a nuisance in astronomical cameras, they can also be identified as a signal in idle camera image sensors. We present the Distributed Electronic Cosmic-ray Observatory (DECO), a platform for outreach and education as well as for citizen science. Consisting of an app and associated database and web site, DECO harnesses the power of distributed camera image sensors for cosmic-ray detection.

  8. Low energy conversion electron detection in superfluid He3 at ultra-low temperature

    E-Print Network [OSTI]

    E. Moulin; C. Winkelmann; J. F. Macias-Perez; Yu. M. Bunkov; H. Godfrin; D. Santos

    2005-04-12

    We report on the first results of the MACHe3 (MAtrix of Cells of Helium 3) prototype experiment concerning the measurement of low energy conversion electrons at ultra-low temperature. For the first time, the feasibility of the detection of low energy electrons is demonstrated in superfluid He3-B cooled down to 100 microK. Low energy electrons at 7.3 keV coming from the K shell conversion of the 14.4 keV nuclear transition of a low activity Co57 source are detected, opening the possibility to use a He3-based detector for the detection of Weakly Interacting Massive Particles (WIMPs) which are expected to release an amount of energy higher-bounded by 5.6 keV.

  9. Crack detection diagnostics using ultrasonic insonification

    E-Print Network [OSTI]

    Jarmer, Gregory James Sylvester

    2009-01-01

    xiii Chapter 1 Structural Health Monitoring . . . . 1.1Active Sensors for Structural Health Monitoring. Journal ofC.R. Farrar. Structural health monitoring using statistical

  10. Cantilever MEMS Detection ofCantilever MEMS Detection of CancerCancer

    E-Print Network [OSTI]

    Petta, Jason

    Cantilever MEMS Detection ofCantilever MEMS Detection of CancerCancer O. Bravo, C. Milburn, W, NJ 08544 #12;OutlineOutline Introduction of bioMEMS AFM platform schematics Nanoindentations Vimentin antigen Graphs and data Clinical implications Future work #12;Introduction to BioMEMS Structure

  11. PRESSURE ACTIVATED SEALANT TECHNOLOGY

    SciTech Connect (OSTI)

    Michael A. Romano

    2004-04-01

    The objective of this project is to develop new, efficient, cost effective methods of internally sealing natural gas pipeline leaks through the application of differential pressure activated sealants. In researching the current state of the art for gas pipeline sealing technologies we concluded that if the project was successful, it appeared that pressure activated sealant technology would provide a cost effective alternative to existing pipeline repair technology. From our analysis of current field data for a 13 year period from 1985 to 1997 we were able to identify 205 leaks that were candidates for pressure activated sealant technology, affirming that pressure activated sealant technology is a viable option to traditional external leak repairs. The data collected included types of defects, areas of defects, pipe sizes and materials, incident and operating pressures, ability of pipeline to be pigged and corrosion states. This data, and subsequent analysis, was utilized as a basis for constructing applicable sealant test modeling.

  12. Undergraduate Activities Fund

    E-Print Network [OSTI]

    Undergraduate Activities Fund Brought to you by the Undergraduate Finance Committee #12;General UAF industry representatives informed students on the current state of the mining and oil and gas industries

  13. Student Activities Office 

    E-Print Network [OSTI]

    Unknown

    2011-08-17

    School-based extracurricular activity participation has been linked to positive behavioral and academic outcomes; however, little is known about the participation and outcomes of participation of Hispanic students, a group that is historically...

  14. Detection of superimposed periodic signals using wavelets

    E-Print Network [OSTI]

    X. Otazu; M. Ribo; M. Peracaula; J. M. Paredes; J. Nunez

    2002-02-05

    In this paper we present a wavelet based algorithm that is able to detect superimposed periodic signals in data with low signal-noise ratio. In this context, the results given by classical period determination methods highly depend on the intrinsic characteristics of each periodic signal, like amplitude or profile. It is then difficult to detect the different periods present in the data set. The results given by the wavelet based method for period determination we present here are independent of the characteristics of the signals.

  15. Nonlinear nanomechanical oscillators for ultrasensitive inertial detection

    DOE Patents [OSTI]

    Datskos, Panagiotis George; Lavrik, Nickolay V

    2013-08-13

    A system for ultrasensitive mass and/or force detection of this invention includes a mechanical oscillator driven to oscillate in a nonlinear regime. The mechanical oscillator includes a piezoelectric base with at least one cantilever resonator etched into the piezoelectric base. The cantilever resonator is preferably a nonlinear resonator which is driven to oscillate with a frequency and an amplitude. The system of this invention detects an amplitude collapse of the cantilever resonator at a bifurcation frequency as the cantilever resonator stimulated over a frequency range. As mass and/or force is introduced to the cantilever resonator, the bifurcation frequency shifts along a frequency axis in proportion to the added mass.

  16. A comparison of edge detection operators 

    E-Print Network [OSTI]

    Lee, Juck Sik

    1986-01-01

    , (a. IS) where I(z, y) is the image, and & is the convolution operator. By the derivative rule for convolutions, f(z, y) = G(x, y) ~ V I(z, y) = V G(x, y) w I(x, y). (2. 16) V'zG(z, y) is given by the following expression 8 G(z, y) 8 G(z, y) '7'G... Operator 5 7 10 ll III DISCUSSION ON EDGE DETECTION OPERATORS 16 A. Transfer Function B. Filtering C. Differentiation D. Zero Crossing E. Thresholding F. Edge Length and Displacement 17 19 20 22 24 25 IV EDGE DETECTION PERFORMANCE...

  17. Analog detection for cavity lifetime spectroscopy

    DOE Patents [OSTI]

    Zare, Richard N. (Stanford, CA); Harb, Charles C. (Palo Alto, CA); Paldus, Barbara A. (Mountain View, CA); Spence, Thomas G. (Palo Alto, CA)

    2003-01-01

    An analog detection system for determining a ring-down rate or decay rate 1/.tau. of an exponentially decaying ring-down beam issuing from a lifetime or ring-down cavity during a ring-down phase. Alternatively, the analog detection system determines a build-up rate of an exponentially growing beam issuing from the cavity during a ring-up phase. The analog system can be employed in continuous wave cavity ring-down spectroscopy (CW CRDS) and pulsed CRDS (P CRDS) arrangements utilizing any type of ring-down cavity including ring-cavities and linear cavities.

  18. Analog detection for cavity lifetime spectroscopy

    DOE Patents [OSTI]

    Zare, Richard N. (Stanford, CA); Harb, Charles C. (Palo Alto, CA); Paldus, Barbara A. (Mountain View, CA); Spence, Thomas G. (Palo Alto, CA)

    2001-05-15

    An analog detection system for determining a ring-down rate or decay rate 1/.tau. of an exponentially decaying ring-down beam issuing from a lifetime or ring-down cavity during a ring-down phase. Alternatively, the analog detection system determines a build-up rate of an exponentially growing beam issuing from the cavity during a ring-up phase. The analog system can be employed in continuous wave cavity ring-down spectroscopy (CW CRDS) and pulsed CRDS (P CRDS) arrangements utilizing any type of ring-down cavity including ring-cavities and linear cavities.

  19. System for particle concentration and detection

    DOE Patents [OSTI]

    Morales, Alfredo M.; Whaley, Josh A.; Zimmerman, Mark D.; Renzi, Ronald F.; Tran, Huu M.; Maurer, Scott M.; Munslow, William D.

    2013-03-19

    A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip.

  20. System For Detection Of Hazardous Events

    DOE Patents [OSTI]

    Kulesz, James J [Oak Ridge, TN; Worley, Brian A [Knoxville, TN

    2005-08-16

    A system for detecting the occurrence of anomalies, includes a plurality of spaced apart nodes, with each node having adjacent nodes, each of the nodes having one or more sensors associated with the node and capable of detecting anomalies, and each of the nodes having a controller connected to the sensors associated with the node. The system also includes communication links between adjacent nodes, whereby the nodes form a network. Each controller is programmed to query its adjacent nodes to assess the status of the adjacent nodes and the communication links.

  1. System for detection of hazardous events

    DOE Patents [OSTI]

    Kulesz, James J.; Worley, Brian A.

    2006-05-23

    A system for detecting the occurrence of anomalies, includes a plurality of spaced apart nodes, with each node having adjacent nodes, each of the nodes having one or more sensors associated with the node and capable of detecting anomalies, and each of the nodes having a controller connected to the sensors associated with the node. The system also includes communication links between adjacent nodes, whereby the nodes form a network. Each controller is programmed to query its adjacent nodes to assess the status of the adjacent nodes and the communication links.

  2. Apparatus and methods for detecting chemical permeation

    DOE Patents [OSTI]

    Vo-Dinh, T.

    1994-12-27

    Apparatus and methods for detecting the permeation of hazardous or toxic chemicals through protective clothing are disclosed. The hazardous or toxic chemicals of interest do not possess the spectral characteristic of luminescence. The apparatus and methods utilize a spectrochemical modification technique to detect the luminescence quenching of an indicator compound which upon permeation of the chemical through the protective clothing, the indicator is exposed to the chemical, thus indicating chemical permeation. The invention also relates to the fabrication of protective clothing materials. 13 figures.

  3. Nonproliferation and safeguarding via ionization detection

    SciTech Connect (OSTI)

    Koster, J.E.; Johnson, J.P.; Steadman, P.

    1995-05-01

    A significant signature of the presence of special nuclear material (SNM) is ionizing radiation. SNM naturally decays with the emission of alpha particles, gamma rays, and neutrons. Detecting and monitoring these emissions is an important capability for international safeguards. A new detection method collects the ions produced by such radiation in ambient air. Alpha particles in particular are specific to heavy nuclei but have very short range. The ions produced by an alpha, however, can be transported tens of meters to an ion detector. These new monitors are rugged, very sensitive, respond in real time, and in most cases are quite portable.

  4. Nauru Island Effect Detection Data Set

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Long, Chuck

    2010-07-15

    During Nauru99 it was noted that the island was producing small clouds that advected over the ARM site. The Nauru Island Effect Study was run for 1.5 years and the methodology developed to detect the occurrence. Nauru ACRF downwelling SW, wind direction, and air temperature data are used, along with downwelling SW data from Licor radiometers located on the southern end of the island near the airport landing strip. A statistical analysis and comparison of data from the two locations is used to detect the likely occurrence of an island influence on the Nauru ACRF site data

  5. Supernova neutrino detection at spallation neutron sources

    E-Print Network [OSTI]

    Huang, Ming-Yang; Young, Bing-Lin

    2015-01-01

    With considering the supernova shock effects, the Mikheyev-Smirnov-Wolfenstein effects, the neutrino collective effects, and the Earth matter effects, the detection of supernova neutrinos at China Spallation Neutron Sources is studied and the event numbers of different flavor supernova neutrinos observed through various reaction channels are calculated with the neutrino energy spectra described by the Fermi-Dirac distribution and "beta fit" distribution respectively. Furthermore, the numerical calculation method of supernova neutrino detection on the Earth is applied to some other spallation neutron sources, and the total event numbers of supernova neutrinos observed through different reactions channels are given.

  6. Method and system for detecting an explosive

    DOE Patents [OSTI]

    Reber, Edward L. (Idaho Falls, ID); Rohde, Kenneth W. (Idaho Falls, ID); Blackwood, Larry G. (Bozeman, MT)

    2010-12-07

    A method and system for detecting at least one explosive in a vehicle using a neutron generator and a plurality of NaI detectors. Spectra read from the detectors is calibrated by performing Gaussian peak fitting to define peak regions, locating a Na peak and an annihilation peak doublet, assigning a predetermined energy level to one peak in the doublet, and predicting a hydrogen peak location based on a location of at least one peak of the doublet. The spectra are gain shifted to a common calibration, summed for respective groups of NaI detectors, and nitrogen detection analysis performed on the summed spectra for each group.

  7. Detection of electrophilic and nucleophilic chemical agents

    DOE Patents [OSTI]

    McElhanon, James R.; Shepodd, Timothy J.

    2014-08-12

    A "real time" method for detecting chemical agents generally and particularly electrophilic and nucleophilic species by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species. By bonding or otherwise attaching these precursor molecules to a surface or substrate they can be used in numerous applications.

  8. Portable chemical detection system with intergrated preconcentrator

    DOE Patents [OSTI]

    Baumann, Mark J.; Brusseau, Charles A.; Hannum, David W.; Linker, Kevin L.

    2005-12-27

    A portable system for the detection of chemical particles such as explosive residue utilizes a metal fiber substrate that may either be swiped over a subject or placed in a holder in a collection module which can shoot a jet of gas at the subject to dislodge residue, and then draw the air containing the residue into the substrate. The holder is then placed in a detection module, which resistively heats the substrate to evolve the particles, and provides a gas flow to move the particles to a miniature detector in the module.

  9. Nauru Island Effect Detection Data Set

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Long, Chuck

    During Nauru99 it was noted that the island was producing small clouds that advected over the ARM site. The Nauru Island Effect Study was run for 1.5 years and the methodology developed to detect the occurrence. Nauru ACRF downwelling SW, wind direction, and air temperature data are used, along with downwelling SW data from Licor radiometers located on the southern end of the island near the airport landing strip. A statistical analysis and comparison of data from the two locations is used to detect the likely occurrence of an island influence on the Nauru ACRF site data

  10. ACTIVITY NETWORKS JIM MORROW

    E-Print Network [OSTI]

    Morrow, James A.

    fl(pq) = 0. A critical_path_is a longest path from S to F . An activity is critical if and only if it is on a critical path. There is an algorithm for computing e(p) which can be easily modi- fied to compute l to be the length of the longest path from S to F . The earliest_starting_time_, e(p), of activ- ity pq is defined

  11. Toroidal optical activity

    E-Print Network [OSTI]

    Raybould, T A; Papasimakis, N; Kuprov, I; Youngs, I; Chen, W T; Tsai, D P; Zheludev, N I

    2015-01-01

    Optical activity is ubiquitous across natural and artificial media and is conventionally understood in terms of scattering from electric and magnetic moments. Here we demonstrate experimentally and confirm numerically a type of optical activity that cannot be attributed to electric and magnetic multipoles. We show that our observations can only be accounted for by the inclusion of the toroidal dipole moment, the first term of the recently established peculiar family of toroidal multipoles.

  12. Low activation ferritic alloys

    DOE Patents [OSTI]

    Gelles, David S. (West Richland, WA); Ghoniem, Nasr M. (Granada Hills, CA); Powell, Roger W. (Pasco, WA)

    1986-01-01

    Low activation ferritic alloys, specifically bainitic and martensitic stainless steels, are described for use in the production of structural components for nuclear fusion reactors. They are designed specifically to achieve low activation characteristics suitable for efficient waste disposal. The alloys essentially exclude molybdenum, nickel, nitrogen and niobium. Strength is achieved by substituting vanadium, tungsten, and/or tantalum in place of the usual molybdenum content in such alloys.

  13. Low activation ferritic alloys

    DOE Patents [OSTI]

    Gelles, D.S.; Ghoniem, N.M.; Powell, R.W.

    1985-02-07

    Low activation ferritic alloys, specifically bainitic and martensitic stainless steels, are described for use in the production of structural components for nuclear fusion reactors. They are designed specifically to achieve low activation characteristics suitable for efficient waste disposal. The alloys essentially exclude molybdenum, nickel, nitrogen and niobium. Strength is achieved by substituting vanadium, tungsten, and/or tantalum in place of the usual molybdenum content in such alloys.

  14. Measuring indigenous photosynthetic organisms to detect chemical warefare agents in water

    DOE Patents [OSTI]

    Greenbaum, Elias; Sanders, Charlene A.

    2005-11-15

    A method of testing water to detect the presence of a chemical or biological warfare agent is disclosed. The method is carried out by establishing control data by providing control water containing indigenous organisms but substantially free of a chemical and a biological warfare agent. Then measuring photosynthetic activity of the control water with a fluorometer to obtain control data to compare with test data to detect the presence of the chemical or agent. The test data is gathered by providing test water comprising the same indigenous organisms as contained in the control water. Further, the test water is suspected of containing the chemical or agent to be tested for. Photosynthetic activity is also measured by fluorescence induction in the test water using a fluorometer.

  15. Determining plutonium mass in spent fuel using Cf-252 interrogation with prompt neutron detection

    SciTech Connect (OSTI)

    Hu, Jianwei; Tobin, Stephen J; Menlove, Howard O; Croft, Stephen

    2010-01-01

    {sup 252}Cf Interrogation with Prompt Neutron (CIPN) detection is proposed as one of 14 NDA techniques to determine Pu mass in spent fuel assemblies (FAs). CIPN is a low-cost and portable instrument, and it looks like a modified fork detector combined with an active interrogation source. Fission chamber (FC) is chosen as neutron detector because of its insensitivity to {gamma} radiation. The CIPN assay is comprised of two measurements, a background count and an active count, without and with the {sup 252}Cf source next to the fuel respectively. The net signal above background is primarily due to the multiplication of Cf source neutrons caused by the fissile content. The capability of CIPN to detect diversion and to determine fissile content was quantified using MCNPX simulations. New schemes were proposed (such as burnup and cooling time correction, etc.) and the results show that the fissile content of a target spent fuel assembly can be determined using CIPN signal.

  16. Tissue-based water quality biosensors for detecting chemical warfare agents

    DOE Patents [OSTI]

    Greenbaum, Elias (Oak Ridge, TN); Sanders, Charlene A. (Knoxville, TN)

    2003-05-27

    A water quality sensor for detecting the presence of at least one chemical or biological warfare agent includes: a cell; apparatus for introducing water into the cell and discharging water from the cell adapted for analyzing photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms in water; a fluorometer for measuring photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms drawn into the cell; and an electronics package that analyzes raw data from the fluorometer and emits a signal indicating the presence of at least one chemical or biological warfare agent in the water.

  17. Apparatus and methods for real-time detection of explosives devices

    DOE Patents [OSTI]

    Blackburn, Brandon W [Idaho Falls, ID; Hunt, Alan W [Pocatello, ID; Chichester, David L [Idaho Falls, ID

    2014-01-07

    The present disclosure relates, according to some embodiments, to apparatus, devices, systems, and/or methods for real-time detection of a concealed or camouflaged explosive device (e.g., EFPs and IEDs) from a safe stand-off distance. Apparatus, system and/or methods of the disclosure may also be operable to identify and/or spatially locate and/or detect an explosive device. An apparatus or system may comprise an x-ray generator that generates high-energy x-rays and/or electrons operable to contact and activate a metal comprised in an explosive device from a stand-off distance; and a detector operable to detect activation of the metal. Identifying an explosive device may comprise detecting characteristic radiation signatures emitted by metals specific to an EFP, an IED or a landmine. Apparatus and systems of the disclosure may be mounted on vehicles and methods of the disclosure may be performed while moving in the vehicle and from a safe stand-off distance.

  18. NSLS 2009 Activity Report

    SciTech Connect (OSTI)

    Nasta K.; Mona R.

    2009-05-01

    2009 was an incredibly exciting year for light sources at Brookhaven. The National Synchrotron Light Source (NSLS) hosted more than 2,200 visiting researchers, who, along with the about 50 members of our scientific staff, produced a total of 957 publications - about 20 percent of which appeared in premier journals. Covering topics ranging from Alzheimer's disease detection to ethanol-powered fuel cells, a sampling of these findings can be found in this Activity Report. We've also seen the resurfacing of some of our long-time users hard work. I was very proud to hear that two of the three recipients of the 2009 Nobel Prize in Chemistry have ties to the NSLS. Venki Ramakrishnan, a former employee in Brookhaven's biology department and long-time user of the NSLS, now at Cambridge University, and Thomas A. Steitz of Yale University, also a long-time NSLS user, shared the prize with Ada E. Yonath of the Weizmann Institute of Science for their work on the structure and function of the ribosome. In the late 1990s, Ramakrishnan and Steitz used protein crystallography at the NSLS to gather atomic-level images of two ribosome subunits: 30S (Ramakrishnan) and 50S (Steitz). Both laureates solved the high-resolution structures for these subunits based on this data. After struggling with a rough budget for several years, we received excellent funding, and then some, this year. In addition to NSLS operations funding, we received $3 million in funds from the American Recovery and Reinvestment Act (ARRA). We used that additional money for two exciting projects: construction of a full-field x-ray microscope and acquisition of several advanced x-ray detectors. The x-ray microscope will be able to image objects with a targeted spatial resolution of 30 nanometers. This capability will be particularly important for new initiatives in energy research and will prepare our users for the projected 1-nanometer resolution benchmark at the National Synchrotron Light Source II (NSLS-II). The detectors project is expected to increase the throughput of several high-demand beamlines by an order of magnitude as well as enable new classes of experiments. In addition, a huge chunk of ARRA money - $150 million - was put toward accelerating the construction of NSLS-II, which is now taking shape across the street. Now physically much more than just a pile of dirt, NSLS-II was granted Critical Decision 3 status by the Department of Energy (DOE) early last year, giving the official go-ahead for construction. In July, construction began, marked by a groundbreaking ceremony that attracted elected officials, media, and DOE, Battelle, and Stony Brook University representatives from across the state and the country. As progress on NSLS-II continues, we're working with Stony Brook University to identify ways to capitalize on the facility's unique capabilities through the Joint Photon Sciences Institute (JPSI). Included in this effort is a series of workshops to encourage the development and application of the photon sciences with collaborative research between industries, universities, and national laboratories. We helped host three of these workshops this year, focusing on microelectronics, energy storage, and materials in next-generation energy systems. The conversation and ideas generated at these meetings has been fresh and valuable and we hope to use this model to organize research opportunities in other scientific fields. Also this year: Brookhaven was deemed the lead institution for one of DOE's 46 Energy Frontier Research Centers, focused on understanding the underlying nature of superconductivity in complex materials by using techniques at the NSLS and CFN; DOE awarded a $100,000 supplemental grant to our detector program to continue the development of a new generation of x-ray detectors that use germanium sensors, which, at high energies, are much more efficient than equivalent ones based on silicon; and funding for one of our largest consortia, Case Western Reserve University's Center for Synchrotron Biosciences (CSB), was renewed through the National Inst

  19. Sensor Management Problems of Nuclear Detection Tamra Carpenter

    E-Print Network [OSTI]

    ) detection using a fleet of mobile radiation sensors; and 4) data sampling strategies for nuclear detection. The nuclear and radiological materials whose detection is of particular concern are radiation dispersion detection: Border crossings ­ At borders, vehicles move through radiation portal monitors (RPMs

  20. Transcription factor-based biosensors for detecting dicarboxylic acids

    SciTech Connect (OSTI)

    Dietrich, Jeffrey; Keasling, Jay

    2014-02-18

    The invention provides methods and compositions for detecting dicarboxylic acids using a transcription factor biosensor.

  1. UNIVERSITY OF CALGARY Refined Freeman-Durden for Harvest Detection

    E-Print Network [OSTI]

    Calgary, University of

    detection in rice paddy fields. However, harvest detection for other crops without a smooth underlying water#12;UNIVERSITY OF CALGARY Refined Freeman-Durden for Harvest Detection using PolSAR data by Sina is one of the main challenges of the current century. Harvest detection, as an input for decision making

  2. Using Near-Infrared Light To Detect Breast Cancer

    E-Print Network [OSTI]

    Fantini, Sergio

    Using Near-Infrared Light To Detect Breast Cancer Using Near-Infrared Light To Detect Breast Cancer News 25 T he idea of using light to non- invasively detect breast cancer has been revisited in the past of selectively labeling breast tumors may open new opportunities in the optical detection of breast cancer

  3. Method for detecting sophisticated cyber attacks

    SciTech Connect (OSTI)

    Potok, Thomas E. (Oak Ridge, TN)

    2008-11-18

    A method of analyzing computer intrusion detection information that looks beyond known attacks and abnormal access patterns to the critical information that an intruder may want to access. Unique target identifiers and type of work performed by the networked targets is added to audit log records. Analysis using vector space modeling, dissimilarity matrix comparison, and clustering of the event records is then performed.

  4. Simple Microwave Method for Detecting Water Holdup

    E-Print Network [OSTI]

    Iqbal, Sheikh Sharif

    combinations of oil and water contents. The #12;reflection responses (S11) of the pipe with water level rangingSimple Microwave Method for Detecting Water Holdup Sheikh S. I., Alqurashi K. Y., Ragheb H to determine the water holdup of a near horizontal oil carrying pipeline. This technique is particularly useful

  5. Unifying sensor fault detection with energy conservation

    E-Print Network [OSTI]

    Dobson, Simon

    Unifying sensor fault detection with energy conservation Lei Fang and Simon Dobson School energy usage. Section 2 presents our framework, which is evaluated in section 3 by means of some reliability. Sensors are often energy-hungry and cannot operate over the long term, and the data they gather

  6. Method and apparatus for detecting an analyte

    DOE Patents [OSTI]

    Allendorf, Mark D. (Pleasanton, CA); Hesketh, Peter J. (Atlanta, GA)

    2011-11-29

    We describe the use of coordination polymers (CP) as coatings on microcantilevers for the detection of chemical analytes. CP exhibit changes in unit cell parameters upon adsorption of analytes, which will induce a stress in a static microcantilever upon which a CP layer is deposited. We also describe fabrication methods for depositing CP layers on surfaces.

  7. Composite scintillators for detection of ionizing radiation

    DOE Patents [OSTI]

    Dai, Sheng (Knoxville, TN) [Knoxville, TN; Stephan, Andrew Curtis (Knoxville, TN) [Knoxville, TN; Brown, Suree S. (Knoxville, TN) [Knoxville, TN; Wallace, Steven A. (Knoxville, TN) [Knoxville, TN; Rondinone, Adam J [Knoxville, TN

    2010-12-28

    Applicant's present invention is a composite scintillator having enhanced transparency for detecting ionizing radiation comprising a material having optical transparency wherein said material comprises nano-sized objects having a size in at least one dimension that is less than the wavelength of light emitted by the composite scintillator wherein the composite scintillator is designed to have selected properties suitable for a particular application.

  8. Quantitative multiplex detection of pathogen biomarkers

    DOE Patents [OSTI]

    Mukundan, Harshini; Xie, Hongzhi; Swanson, Basil I; Martinez, Jennifer; Grace, Wynne K

    2014-10-14

    The present invention addresses the simultaneous detection and quantitative measurement of multiple biomolecules, e.g., pathogen biomarkers through either a sandwich assay approach or a lipid insertion approach. The invention can further employ a multichannel, structure with multi-sensor elements per channel.

  9. Fuel cell flooding detection and correction

    DOE Patents [OSTI]

    DiPierno Bosco, Andrew (Rochester, NY); Fronk, Matthew Howard (Honeoye Falls, NY)

    2000-08-15

    Method and apparatus for monitoring an H.sub.2 -O.sub.2 PEM fuel cells to detect and correct flooding. The pressure drop across a given H.sub.2 or O.sub.2 flow field is monitored and compared to predetermined thresholds of unacceptability. If the pressure drop exists a threshold of unacceptability corrective measures are automatically initiated.

  10. Possibility of a photometric detection of "exomoons"

    E-Print Network [OSTI]

    Szabó, G M; Diveki, Z; Simon, A; Szabo, Gy. M.; Diveki, Zs.

    2006-01-01

    We examined which exo-systems contain moons that may be detected in transit. We numerically modeled transit light curves of Earth-like and giant planets that cointain moons with 0.005--0.4 Earth-mass. The orbital parameters were randomly selected, but the entire system fulfilled Hill-stability. We conclude that the timing effect is caused by two scenarios: the motion of the planet and the moon around the barycenter. Which one dominates depends on the parameters of the system. Already planned missions (Kepler, COROT) may be able to detect the moon in transiting extrasolar Earth-Moon-like systems with a 20% probability. From our sample of 500 free-designed systems, 8 could be detected with the photometric accuracy of 0.1 mmag and a 1 minute sampling, and one contains a stony planet. With ten times better accuracy, 51 detections are expected. All such systems orbit far from the central star, with the orbital periods at least 200 and 10 days for the planet and the moon, while they contain K- and M-dwarf stars. Fi...

  11. Structural Damage Detection and Localization Using NETSHM

    E-Print Network [OSTI]

    Gnawali, Omprakash

    Structural Damage Detection and Localization Using NETSHM Krishna Chintalapudi, Jeongyeup Paek and localize damage in large civil structures. Structural engineers often implement and test SHM algorithms the intricacies of wireless networking, or the details of sensor data acquisition. We have implemented a damage

  12. Image Watermarking for Tamper Detection Jiri Fridrich

    E-Print Network [OSTI]

    Fridrich, Jessica

    Image Watermarking for Tamper Detection Jiri Fridrich Center for Intelligent Systems, SUNY 87501 fridrich@binghamton.edu Abstract We propose an oblivious watermarking technique for tamper could probably reveal some cases of tampering, but a capable attacker with enough expertise can always

  13. Laser speckle photography for surface tampering detection

    E-Print Network [OSTI]

    Shih, YiChang

    2012-01-01

    It is often desirable to detect whether a surface has been touched, even when the changes made to that surface are too subtle to see in a pair of before and after images. To address this challenge, we introduce a new imaging ...

  14. Laser speckle photography for surface tampering detection

    E-Print Network [OSTI]

    Shih, YiChang

    It is often desirable to detect whether a surface has been touched, even when the changes made to that surface are too subtle to see in a pair of before and after images. To address this challenge, we introduce a new imaging ...

  15. Method for detecting gas turbine engine flashback

    DOE Patents [OSTI]

    Singh, Kapil Kumar; Varatharajan, Balachandar; Kraemer, Gilbert Otto; Yilmaz, Ertan; Lacy, Benjamin Paul

    2012-09-04

    A method for monitoring and controlling a gas turbine, comprises predicting frequencies of combustion dynamics in a combustor using operating conditions of a gas turbine, receiving a signal from a sensor that is indicative of combustion dynamics in the combustor, and detecting a flashback if a frequency of the received signal does not correspond to the predicted frequencies.

  16. Binderless composite scintillator for neutron detection

    DOE Patents [OSTI]

    Hodges, Jason P [Knoxville, TN; Crow, Jr; Lowell, M [Oak Ridge, TN; Cooper, Ronald G [Oak Ridge, TN

    2009-03-10

    Composite scintillator material consisting of a binderless sintered mixture of a Lithium (Li) compound containing .sup.6Li as the neutron converter and Y.sub.2SiO.sub.5:Ce as the scintillation phosphor, and the use of this material as a method for neutron detection. Other embodiments of the invention include various other Li compounds.

  17. Coated semiconductor devices for neutron detection

    DOE Patents [OSTI]

    Klann, Raymond T. (Bolingbrook, IL); McGregor, Douglas S. (Whitmore Lake, MI)

    2002-01-01

    A device for detecting neutrons includes a semi-insulated bulk semiconductor substrate having opposed polished surfaces. A blocking Schottky contact comprised of a series of metals such as Ti, Pt, Au, Ge, Pd, and Ni is formed on a first polished surface of the semiconductor substrate, while a low resistivity ("ohmic") contact comprised of metals such as Au, Ge, and Ni is formed on a second, opposed polished surface of the substrate. In one embodiment, n-type low resistivity pinout contacts comprised of an Au/Ge based eutectic alloy or multi-layered Pd/Ge/Ti/Au are also formed on the opposed polished surfaces and in contact with the Schottky and ohmic contacts. Disposed on the Schottky contact is a neutron reactive film, or coating, for detecting neutrons. The coating is comprised of a hydrogen rich polymer, such as a polyolefin or paraffin; lithium or lithium fluoride; or a heavy metal fissionable material. By varying the coating thickness and electrical settings, neutrons at specific energies can be detected. The coated neutron detector is capable of performing real-time neutron radiography in high gamma fields, digital fast neutron radiography, fissile material identification, and basic neutron detection particularly in high radiation fields.

  18. A "Poisoning" Attack Against Online Anomaly Detection

    E-Print Network [OSTI]

    Freytag, Johann-Christoph

    A "Poisoning" Attack Against Online Anomaly Detection Marius Kloft Department of Computer Science it is robust against targeted "poisoning" attacks. The latter have been first investigated by Nelson et al. [1 of all data points observed so far. The key idea of a poisoning attack is to insert specially crafted

  19. A MULTIVARIATE OUTLIER DETECTION P. Filzmoser

    E-Print Network [OSTI]

    Filzmoser, Peter

    A MULTIVARIATE OUTLIER DETECTION METHOD P. Filzmoser Department of Statistics and Probability of multivariate outliers is proposed which accounts for the data structure and sample size. The cut-off value no distinction is made between outliers and extremes of a distribution. The basis for multivariate outlier

  20. Parametric probability distributions for anomalous change detection

    SciTech Connect (OSTI)

    Theiler, James P; Foy, Bernard R; Wohlberg, Brendt E; Scovel, James C

    2010-01-01

    The problem of anomalous change detection arises when two (or possibly more) images are taken of the same scene, but at different times. The aim is to discount the 'pervasive differences' that occur thoughout the imagery, due to the inevitably different conditions under which the images were taken (caused, for instance, by differences in illumination, atmospheric conditions, sensor calibration, or misregistration), and to focus instead on the 'anomalous changes' that actually take place in the scene. In general, anomalous change detection algorithms attempt to model these normal or pervasive differences, based on data taken directly from the imagery, and then identify as anomalous those pixels for which the model does not hold. For many algorithms, these models are expressed in terms of probability distributions, and there is a class of such algorithms that assume the distributions are Gaussian. By considering a broader class of distributions, however, a new class of anomalous change detection algorithms can be developed. We consider several parametric families of such distributions, derive the associated change detection algorithms, and compare the performance with standard algorithms that are based on Gaussian distributions. We find that it is often possible to significantly outperform these standard algorithms, even using relatively simple non-Gaussian models.

  1. All row, planar fault detection system

    DOE Patents [OSTI]

    Archer, Charles Jens; Pinnow, Kurt Walter; Ratterman, Joseph D; Smith, Brian Edward

    2013-07-23

    An apparatus, program product and method for detecting nodal faults may simultaneously cause designated nodes of a cell to communicate with all nodes adjacent to each of the designated nodes. Furthermore, all nodes along the axes of the designated nodes are made to communicate with their adjacent nodes, and the communications are analyzed to determine if a node or connection is faulty.

  2. Fusion Protein Products Screen Purify Detect Cleave

    E-Print Network [OSTI]

    Lebendiker, Mario

    Fusion Protein Products · Screen · Purify · Detect · Cleave Fusion Protein Products · Screen researchers look to plasmid vectors to express fusion proteins, they find themselves in need of methods proteins is also included for those fusion proteins that may have an inaccessible tag. Pierce offers a host

  3. Automatic Decision Detection in Meeting Speech 

    E-Print Network [OSTI]

    Hsueh, Pei-Yun; Moore, Johanna D.

    2010-11-01

    are not sufficient for locating decision points from meeting archives. In this paper, we present the AMI DecisionDetector, a system that automatically detects and highlights where the decision-related conversations are. In this paper, we apply the models developed...

  4. Digital radiographic systems detect boiler tube cracks

    SciTech Connect (OSTI)

    Walker, S. [EPRI, Charlotte, NC (United States)

    2008-06-15

    Boiler water wall leaks have been a major cause of steam plant forced outages. But conventional nondestructive evaluation techniques have a poor track record of detecting corrosion fatigue cracking on the inside surface of the cold side of waterwall tubing. EPRI is performing field trials of a prototype direct-digital radiographic system that promises to be a game changer. 8 figs.

  5. Breast Cancer Detection Using Multilevel Thresholding

    E-Print Network [OSTI]

    Rejani, Y Ireaneus Anna

    2009-01-01

    This paper presents an algorithm which aims to assist the radiologist in identifying breast cancer at its earlier stages. It combines several image processing techniques like image negative, thresholding and segmentation techniques for detection of tumor in mammograms. The algorithm is verified by using mammograms from Mammographic Image Analysis Society. The results obtained by applying these techniques are described.

  6. Direct Detection of Nonbaryonic Dark Matter

    E-Print Network [OSTI]

    Laura Baudis; H. V. Klapdor-Kleingrothaus

    2000-03-29

    Weakly Interacting Massive Particles (WIMPs) are leading candidates for the dominant part of the mass density of the Universe. Here we will review direct WIMP detection techniques by giving examples of currently running experiments, and present the status of the most promising future projects.

  7. Active System For Monitoring Volcanic Activity- A Case Study...

    Open Energy Info (EERE)

    Central Japan Jump to: navigation, search OpenEI Reference LibraryAdd to library Journal Article: Active System For Monitoring Volcanic Activity- A Case Study Of The...

  8. Optical-Infrared Properties of Faint 1.3 mm Sources Detected with ALMA

    E-Print Network [OSTI]

    Hatsukade, Bunyo; Yabe, Kiyoto; Seko, Akifumi; Makiya, Ryu; Akiyama, Masayuki

    2015-01-01

    We report optical-infrared (IR) properties of faint 1.3 mm sources (S_1.3mm = 0.2-1.0 mJy) detected with the Atacama Large Millimeter/submillimeter Array (ALMA) in the Subaru/XMM-Newton Deep Survey (SXDS) field. We searched for optical/IR counterparts of 8 ALMA-detected sources (>=4.0 sigma, the sum of the probability of spurious source contamination is ~1) in a K-band source catalog. Four ALMA sources have K-band counterpart candidates within a 0.4" radius. Comparison between ALMA-detected and undetected K-band sources in the same observing fields shows that ALMA-detected sources tend to be brighter, more massive, and more actively forming stars. While many of the ALMA-identified submillimeter-bright galaxies (SMGs) in previous studies lie above the sequence of star-forming galaxies in stellar mass--star-formation rate plane, our ALMA sources are located in the sequence, suggesting that the ALMA-detected faint sources are more like `normal' star-forming galaxies rather than `classical' SMGs. We found a regio...

  9. High repetition rate laser-induced breakdown spectroscopy using acousto-optically gated detection

    SciTech Connect (OSTI)

    Po?ízka, Pavel [BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Straße 11, D-12489 Berlin (Germany); Institute of Physical Engineering, Faculty of Mechanical Engineering, Brno University of Technology, Technicka 2896/2, 61669 Brno (Czech Republic); Klessen, Benjamin; Gornushkin, Igor; Riedel, Jens [BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Straße 11, D-12489 Berlin (Germany); Kaiser, Jozef [Institute of Physical Engineering, Faculty of Mechanical Engineering, Brno University of Technology, Technicka 2896/2, 61669 Brno (Czech Republic); Panne, Ulrich [BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Straße 11, D-12489 Berlin (Germany); Chemistry Department, Humboldt Universität zu Berlin, Brook-Taylor-Straße 2, D-12489 Berlin (Germany)

    2014-07-15

    This contribution introduces a new type of setup for fast sample analysis using laser-induced breakdown spectroscopy (LIBS). The novel design combines a high repetition rate laser (up to 50 kHz) as excitation source and an acousto-optical modulator (AOM) as a fast switch for temporally gating the detection of the emitted light. The plasma radiation is led through the active medium of the AOM where it is diffracted on the transient ultrasonic Bragg grid. The diffracted radiation is detected by a compact Czerny-Turner spectrometer equipped with a CCD line detector. Utilizing the new combination of high repetition rate lasers and AOM gated detection, rapid measurements with total integration times of only 10 ms resulted in a limit of detection (LOD) of 0.13 wt.% for magnesium in aluminum alloys. This short integration time corresponds to 100 analyses/s. Temporal gating of LIP radiation results in improved LODs and consecutively higher sensitivity of the LIBS setup. Therefore, an AOM could be beneficially utilized to temporally detect plasmas induced by high repetition rate lasers. The AOM in combination with miniaturized Czerny-Turner spectrometers equipped with CCD line detectors and small footprint diode pumped solid state lasers results in temporally gateable compact LIBS setups.

  10. Direct, Rapid, and Label-Free Detection of Enzyme-Substrate Interactions in Physiological Buffers Using CMOS-Compatible

    E-Print Network [OSTI]

    Reed, Mark

    the activity of the enzyme compared to its natural environment,21 which precludes meaningful extraction of detection of extract accurate enzyme kinetics or consume acidic or basic products and thus alter the pH of their environments,5 suggesting FET

  11. Planets around active stars

    E-Print Network [OSTI]

    J. Setiawan; P. Weise; Th. Henning; A. P. Hatzes; L. Pasquini; L. da Silva; L. Girardi; O. von der Luhe; M. P. Dollinger; A. Weiss; K. Biazzo

    2007-04-17

    We present the results of radial velocity measurements of two samples of active stars. The first sample contains field G and K giants across the Red Giant Branch, whereas the second sample consists of nearby young stars (d 1999 - 2002) and continued since 2003 at 2.2 m MPG/ESO telescope. We observed stellar radial velocity variations which originate either from the stellar activity or the presence of stellar/substellar companions. By means of a bisector technique we are able to distinguish the sources of the radial velocity variation. Among them we found few candidates of planetary companions, both of young stars and G-K giants sample.

  12. 4-H Activities 

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10

    ? are heard often when 4-H members work and learn together. Preparing and presenting demonstrations and illustrated talks help 4-H members gain additional knowl- edge and learn new skills and practices. Younger mem- bers start with easy-to-do ?show and tell... decisions ver- bally. ? Tolerant of other?s decisions. ? Use group activities to increase their interest in 4-H club work. ? Apply what was learned through judging in everyday living. Community Service Community service activities enable 4-H mem- bers...

  13. Microgrid Activities | Department of Energy

    Office of Environmental Management (EM)

    Microgrids Microgrid Activities Microgrid Activities Federal programs, institutions, and the private sector are increasing microgrid development and deployment. The number of...

  14. Active and passive plasmonic devices

    E-Print Network [OSTI]

    Pourabdollah Nezhad, Maziar

    2007-01-01

    G. Mattiussi, and P. Berini, "Passive integrated opticsCALIFORNIA, SAN DIEGO Active and Passive Plasmonic Devices ADISSERTATION Active and Passive Plasmonic Devices by Maziar

  15. Principal Building Activities--1995 CBECS

    U.S. Energy Information Administration (EIA) Indexed Site

    Detailed Tables > Principal Building Activities Table Number of Buildings, Total Floorspace, and Total Site and Primary Energy Consumption for All Principal Building Activities,...

  16. Applied change of mean detection techniques for HVAC fault detection and diagnosis and power monitoring

    E-Print Network [OSTI]

    Hill, Roger Owen

    1995-01-01

    A signal processing technique, the detection of abrupt changes in a time-series signal, is implemented with two different applications related to energy use in buildings. The first application is a signal pre-processor for ...

  17. Linking Europa's plume activity to tides, tectonics, and liquid water

    E-Print Network [OSTI]

    Rhoden, Alyssa R; Roth, Lorenz; Retherford, Kurt

    2015-01-01

    Much of the geologic activity preserved on Europa's icy surface has been attributed to tidal deformation, mainly due to Europa's eccentric orbit. Although the surface is geologically young (30 - 80 Myr), there is little information as to whether tidally-driven surface processes are ongoing. However, a recent detection of water vapor near Europa's south pole suggests that it may be geologically active. Initial observations indicated that Europa's plume eruptions are time-variable and may be linked to its tidal cycle. Saturn's moon, Enceladus, which shares many similar traits with Europa, displays tidally-modulated plume eruptions, which bolstered this interpretation. However, additional observations of Europa at the same time in its orbit failed to yield a plume detection, casting doubt on the tidal control hypothesis. The purpose of this study is to analyze the timing of plume eruptions within the context of Europa's tidal cycle to determine whether such a link exists and examine the inferred similarities and...

  18. Improved Fission Neutron Data Base for Active Interrogation of Actinides

    SciTech Connect (OSTI)

    Pozzi, Sara; Czirr, J. Bart; Haight, Robert; Kovash, Michael; Tsvetkov, Pavel

    2013-11-06

    This project will develop an innovative neutron detection system for active interrogation measurements. Many active interrogation methods to detect fissionable material are based on the detection of neutrons from fission induced by fast neutrons or high-energy gamma rays. The energy spectrum of the fission neutrons provides data to identify the fissionable isotopes and materials such as shielding between the fissionable material and the detector. The proposed path for the project is as follows. First, the team will develop new neutron detection systems and algorithms by Monte Carlo simulations and bench-top experiments. Next, They will characterize and calibrate detection systems both with monoenergetic and white neutron sources. Finally, high-fidelity measurements of neutron emission from fissions induced by fast neutrons will be performed. Several existing fission chambers containing U-235, Pu-239, U-238, or Th-232 will be used to measure the neutron-induced fission neutron emission spectra. The challenge for making confident measurements is the detection of neutrons in the energy ranges of 0.01 – 1 MeV and above 8 MeV, regions where the basic data on the neutron energy spectrum emitted from fission is least well known. In addition, improvements in the specificity of neutron detectors are required throughout the complete energy range: they must be able to clearly distinguish neutrons from other radiations, in particular gamma rays and cosmic rays. The team believes that all of these challenges can be addressed successfully with emerging technologies under development by this collaboration. In particular, the collaboration will address the area of fission neutron emission spectra for isotopes of interest in the advanced fuel cycle initiative (AFCI).

  19. EPAct Transportation Regulatory Activities

    SciTech Connect (OSTI)

    2011-11-21

    The U.S. Department of Energy's (DOE) Vehicle Technologies Program manages several transportation regulatory activities established by the Energy Policy Act of 1992 (EPAct), as amended by the Energy Conservation Reauthorization Act of 1998, EPAct 2005, and the Energy Independence and Security Act of 2007 (EISA).

  20. Active-bridge oscillator

    DOE Patents [OSTI]

    Wessendorf, Kurt O. (Albuquerque, NM)

    2001-01-01

    An active bridge oscillator is formed from a differential amplifier where positive feedback is a function of the impedance of one of the gain elements and a relatively low value common emitter resistance. This use of the nonlinear transistor parameter h stabilizes the output and eliminates the need for ALC circuits common to other bridge oscillators.