National Library of Energy BETA

Sample records for deka deci centi

  1. Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels

    E-Print Network [OSTI]

    D. Boda; G. Leaf; J. Fonseca; B. Eisenberg


    The energetics of ionic selectivity in the neuronal sodium channels is studied. A simple model constructed for the selectivity filter of the channel is used. The selectivity filter of this channel type contains aspartate (D), glutamate (E), lysine (K), and alanine (A) residues (the DEKA locus). We use Grand Canonical Monte Carlo simulations to compute equilibrium binding selectivity in the selectivity filter and to obtain various terms of the excess chemical potential from a particle insertion procedure based on Widom's method. We show that K$^{+}$ ions in competition with Na$^{+}$ are efficiently excluded from the selectivity filter due to entropic hard sphere exclusion. The dielectric constant of protein has no effect on this selectivity. Ca$^{2+}$ ions, on the other hand, are excluded from the filter due to a free energetic penalty which is enhanced by the low dielectric constant of protein.

  2. Um Sistema Computacional integrando Suporte `a Decis~ao na Area de Reproduc ~ao Humana

    E-Print Network [OSTI]

    Baranauskas, José Augusto

    desenvolvimento de um sistema computacional que a implementa. Tais elementos permitem informatizar os processos e¸ ~ao. Palavras-chaves: Reproduc¸ ~ao Assistida, Sistemas de Suporte `a Decis~ao, Aprendizado de M´aquina

  3. rillEdge is a software system that provides real-time deci-sion support when drilling oil wells. Decisions are sup-

    E-Print Network [OSTI]

    Aamodt, Agnar

    developed DrillEdge to reduce the cost and decrease the probability of fail- ures in oil well drilling-Time Decision Support System for High Cost Oil Well Drilling Operations Odd Erik Gundersen, Frode Sørmo, AgnarD rillEdge is a software system that provides real-time deci- sion support when drilling oil wells

  4. So How Do THey DeciDe

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque|Sensitive Species3performedValley | Department of Energy How

  5. JOURNAL OF MULTI-CRITERIA DECISION ANALYSIS J. Multi-Crit. Decis. Anal. 15: 4561 (2008)

    E-Print Network [OSTI]

    Statnikov, Alexander


    , 2005; Statnikov and Matusov, 1995), truck frame, multi- stage axial flow compressor for an aircraft stages. In the first stage, based on the tests one must identify the mathematical model of the object and computed data, the latter being determined on the basis of mathematical model. The number of adequacy

  6. Crystal Plasticity Modeling of Deformation and Creep in Polycrystalline Ti-6242

    E-Print Network [OSTI]

    Ghosh, Somnath

    Crystal Plasticity Modeling of Deformation and Creep in Polycrystalline Ti-6242 DHYANJYOTI DEKA computational model based on crystal plasticity for the analysis of two-phase a/b Ti-6242 polycrystalline alloys. A rate-dependent elastic-crystal plas- ticity model is incorporated in this model to accommodate


    E-Print Network [OSTI]

    da Silva, Alberto Rodrigues

    , a meteorologia e sobre as nossas forças. Este tipo de informação geoespacial é crucial para as decisões aos

  8. Understanding Life Cycle Social Impacts in Manufacturing: A processed-based approach

    E-Print Network [OSTI]

    Hutchins, Margot J.; Robinson, Stefanie L.; Dornfeld, David


    supply chains Social impacts Social responsibility Welding aproposed to characterize social impacts and risks associatedmetrics for measuring social impacts and identifying deci-

  9. The Artificial Intelligence (AI) program at the Univer-sity of Michigan comprises a multidisciplinary group

    E-Print Network [OSTI]

    Eustice, Ryan

    The Artificial Intelligence (AI) program at the Univer- sity of Michigan comprises in areas such as healthcare, electronic commerce, and finance. Artificial IntelligenceResearch Bob of intelligent systems. Current projects include research in rational deci- sion making, distributed systems

  10. Preliminary Safety Design RM

    Office of Environmental Management (EM)

    Preliminary Safety Design Review Module March 2010 CD-0 O 0 OFFICE OF Pr C CD-1 F ENVIRO Standard R reliminar Rev Critical Decis CD-2 M ONMENTAL Review Plan ry Safety view Module...

  11. National Environmental Policy Act RM

    Office of Environmental Management (EM)

    National Environmental Policy Act Review Module March 2010 CD- N -0 OFFICE O National E C CD-1 OF ENVIRO Standa Environm Rev Critical Deci CD-2 M ONMENTA ard Review mental P view...

  12. The Role of Psychological Needs for Autonomy, Competence, Relatedness and Money-luxury in State Authenticity 

    E-Print Network [OSTI]

    Renwick, Louisa Catherine


    This study aimed to determine the effects of psychological needs on states of authenticity. Self-determination theory proposes three basic psychological needs, for autonomy, competence and relatedness (Deci & Ryan, 1985). ...

  13. Master Thesis Projects Topics within Agroecology

    E-Print Network [OSTI]

    Bataillon, Thomas

    Master Thesis Projects Topics within Agroecology AgroEnvironmental Management & Agrobiology MSc 2015 #12;1 Preface This catalogue of master thesis projects available in 2015-2016 was prepared to help students in their deci- sions selecting a topic for their thesis project. A number of project

  14. Taylor Hicks' Soul Patrol

    E-Print Network [OSTI]

    Bedwell, David M.

    of Engineering are preparing a Formula One race car to be entered into the annual Formula SAE Project Lucas heard her students wanted to build a Formula One (F1) racing car to enter into an annual national competition, she says the deci- sion to go forward was an easy one. "Mechanical and material engineering

  15. February 2006 / Vol. 56 No. 2 BioScience 121 The history of environmental and resource manage-

    E-Print Network [OSTI]

    Vermont, University of

    (Andrews 1999, Mangun and Henning 1999). Deci- sionmaking approaches tied to evaluations of environmental 1985, Treweek 1999). The ecosystem services approach addresses recent calls for the explicit). For example, Treweek (1999) notes that "while there are well-developed techniques for economic appraisal

  16. Perceptions are the basis for our understanding of the world. For

    E-Print Network [OSTI]

    of symbolic repre- sentation of the outside world; a self-made model of the world. What we perceive really depends essential- ly on unconscious cognitive deci- sions and conclusions. The brain usually makes especially bothered about the actual realities. We cannot force our way to the out- side through the nerves

  17. ORIGINAL ARTICLE Situating adaptation: how governance challenges and perceptions

    E-Print Network [OSTI]

    Yung, Laurie

    Adaptation is situated within multiple, inter- acting social, political, and economic forces. Adaptation socio- political context. Pathways emphasize that current deci- sions are both informed by past actions and shape the landscape of future options. This research examines how adaptation actors in Grand County

  18. Um Modelo de Gest~ao E ciente de Recursos Computacionais Marcos Castilho Renato Carmo

    E-Print Network [OSTI]

    Hexsel, Roberto A

    vez maior. A din^amica que rege a aquisi#24;c~ao de equipamentos e a contrata#24;c~ao de recursos tecnologia, e mais, as decis~oes que norteiam estas compras s~ao muitas vezes tomadas por grupos

  19. Spring, 1999 Prof. Rich Kozick

    E-Print Network [OSTI]

    Kozick, Richard J.

    system. The solar heating system consists of a collector, a rock energy storage bin, a heated space- prised if you have to make some engineering decisions during the design process. Justify the deci- sions for you to think about. Have fun! Problem 1 You are asked to design the logic to control a solar heating

  20. International Journal of Uncertainty, Fuzziness and KnowledgeBased Systems c World Scientific Publishing Company

    E-Print Network [OSTI]

    Kreinovich, Vladik

    Publishing Company INTERVAL­VALUED DEGREES OF BELIEF: APPLICATIONS OF INTERVAL COMPUTATIONS TO EXPERT SYSTEMS doctors successfully cure diseases; expert geologists find oil; expert astronauts know how to dock the experts in the field, there are a few top experts whose deci­ sions turn out to be the most efficient

  1. International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems fc World Scientific Publishing Company

    E-Print Network [OSTI]

    Kreinovich, Vladik

    Publishing Company INTERVAL-VALUED DEGREES OF BELIEF: APPLICATIONS OF INTERVAL COMPUTATIONS TO EXPERT SYSTEMS successfully cure diseases; expert geologists find oil; expert astronauts know how to dock and land the Space in the field, there are a few top experts whose deci- sions turn out to be the most efficient. Since

  2. J. Hebcek et al. (Eds.): ISESS 2013, IFIP AICT 413, pp. 311320, 2013. IFIP International Federation for Information Processing 2013

    E-Print Network [OSTI]

    in the near future. Keywords: Smart Cities, urban safety, urban crime, data visualisation, deci- sion driven Future Internet concepts of "Smart cities" [5], [2]. For example, security in the smart cities alone, a key driver which will aid smart cities to be managed at localised levels in- volves

  3. Integrated Science and Computing Support for National Climate Service PRINCIPAL INVESTIGATOR: Thomas J. Wilbanks

    E-Print Network [OSTI]

    of an information technology (IT)-based bridge between deci- sion support for a National Climate Service and state and technology (S&T), not only regarding climate data and projections but also regarding informatics, visuIntegrated Science and Computing Support for National Climate Service PRINCIPAL INVESTIGATOR

  4. Bonding and Structure of Ceramic-Ceramic Interfaces Kohei Shimamura,1,2,3

    E-Print Network [OSTI]

    Southern California, University of

    interfacial design of high-temperature ceramic composites for broad applications such as power generation [3,4]) play a deci- sive role in determining material properties of ceramics. An archetypal ceramic-ceramic service temperatures in their applications such as turbines in power generators [9]. Though structural

  5. The Slovene Sound System Through Time

    E-Print Network [OSTI]

    Greenberg, Marc L.


    3 ). From a theoretical viewpoint, sound change is conceptualized along the lines of Henning Andersen’s model, in which deductively developed (phonetic) changes create ambiguities that are resolved by abductive deci- sions by speakers about... and Greenberg 1999; the reversal of lenited mediae, G 38 and Green- berg 2001). While structural factors (deductive change or drift, abductive change or phonemic reinterpretation) drive sound change in one direction, stylistic considera- tions for speakers...

  6. The use of milk progesterone assay as an aid to brood mare management 

    E-Print Network [OSTI]

    Honey, Peter Geoffrey


    of th1s study strongly suggested that much of the infertil1ty 1n mares is due to fa1lure to breed mares in close synchrony with ovulat1on. Difficulty 1n interpretation of palpat1on findings and between mare var1ation in teas1ng results contr1buted... most to mares being bred at sub-optimal t1me. Analys1s of milk progesterone data disclosed these management problems. Two add1tional mares were mon1tored on days that breeding manage- ment decis1ons were made. Milk progesterone levels reflected...

  7. A review of "The Jesuits and the Thirty Years War" by Robert Bireley. 

    E-Print Network [OSTI]

    Mark Charles Fissel


    Bireley con- structs a narrative of the Jesuits? activities in church-state politics, diplomacy, and strategic decision-making in the period 1618-1648. He ventures into the four most important Catholic courts of Eu- rope: Vienna, Munich, Paris, and Madrid... into the sphere of advising on political and military deci- sions? At Vienna and Munich the stakes were high, for Bireley demonstrates that at those courts the Jesuit confessors did affect the prosecution of the war. Far from appearing as calculating...

  8. Self-organized Models of Selectivity in Ca and Na Channels

    E-Print Network [OSTI]

    Bob Eisenberg


    A simple pillbox model with two adjustable parameters accounts for the selectivity of both DEEA Ca channels and DEKA Na channels in many ionic solutions of different composition and concentration. Only the side chains are different in the model of the Ca and Na channels. Parameters are the same for both channels in all solutions. 'Pauling' radii are used for ions. No information from crystal structures is used in the model. Side chains are grossly approximated as spheres. The predicted properties of the Na and Ca channels are very different. How can such a simple model give such powerful results when chemical intuition says that selectivity depends on the precise relation of ions and side chains? We use Monte Carlo simulations of this model that determine the most stable-lowest free energy-structure of the ions and side chains. Structure is the computed consequence of the forces in this model. The relationship of ions and side chains vary with ionic solution and are very different in simulations of the Na and Ca channels. Selectivity is a consequence of the 'induced fit' of side chains to ions and depends on the flexibility (entropy) of the side chains as well as their location. The model captures the relation of side chains and ions well enough to account for selectivity of both Na channels and Ca channels in the wide range of conditions measured in experiments. Evidently, the structures in the real Na and Ca channels responsible for selectivity are self-organized, at their free energy minimum. Oversimplified models are enough to account for selectivity if the models calculate the 'most stable' structure as it changes from solution to solution, and mutation to mutation.

  9. A study of physiological responses of lactating dairy cows to summer climatic factors under shaded and non-shaded conditions 

    E-Print Network [OSTI]

    Harris, Dewey Lynn


    &SZ S XD"D A LD?Oil-S'1AD. . D COliDITIOllS A Ti'esLs Deci~~I L, "!~1 . 1AKIIS Appx'o~"eel 89 i, o 8 'Ie 8. :6 ec'. "eA' t 0 al h E Hi Ic i INTRODUCTION REVIEM OF THE LITERATURE EXPErRZ JACAL PROCEDURE 3 24 Nultiple Regressiou Analysis... rigation, and storage of forages grown during the milder seasons. Unfo. tuna"ely, progress in the study of the adverse efi'acts of "hot" cliia'es ac'lng directly on the animals has not been as iWzitful. Sires mosi Gl the high pr oducing dairy breeds have...

  10. Biology and chemical control of the spotted alfalfa aphid 

    E-Print Network [OSTI]

    Downing, Douglas Holland


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  11. DECIGO/BBO as a probe to constrain alternative theories of gravity

    E-Print Network [OSTI]

    Kent Yagi; Takahiro Tanaka


    We calculate how strongly one can constrain the alternative theories of gravity with deci-Hz gravitational wave interferometers such as DECIGO and BBO. Here we discuss Brans-Dicke theory and massive graviton theories as typical examples. We consider the inspiral of compact binaries composed of a neutron star (NS) and an intermediate mass black hole (IMBH) for Brans-Dicke (BD) theory and those composed of a super massive black hole (SMBH) and a black hole (SMBH) for massive graviton theories. Using the restricted 2PN waveforms including spin effects and taking the spin precession into account, we perform the Monte Carlo simulations of $10^4$ binaries to estimate the determination accuracy of binary parameters including the Brans-Dicke parameter $\\omega_{\\mathrm{BD}}$ and the graviton Compton length $\\lambda_g$. Assuming a $(1.4, 10)M_{\\odot}$ NS/BH binary of SNR=$\\sqrt{200}$, the constraint on $\\omega_{\\mathrm{BD}}$ is obtained as $\\omega_{\\mathrm{BD}}>2.32\\times 10^6$, which is 300 times stronger than the estimated constraint from LISA observation. Furthermore, we find that, due to the expected large merger rate of NS/BH binaries of $O(10^4)$ yr$^{-1}$, a statistical analysis yields $\\omega_{\\mathrm{BD}}>3.77\\times10^8$, which is 4 orders of magnitude stronger than the current strongest bound obtained from the solar system experiment. For massive graviton theories, assuming a $(10^6, 10^5)M_{\\odot}$ BH/BH binary at 3Gpc, one can put a constraint $\\lambda_g>3.35\\times10^{20}$cm, on average. This is three orders of magnitude stronger than the one obtained from the solar system experiment. From these results, it is understood that DECIGO/BBO is a very powerful tool for constraining alternative theories of gravity, too.

  12. Distributed Sensor Coordination for Advanced Energy Systems

    SciTech Connect (OSTI)

    Tumer, Kagan


    The ability to collect key system level information is critical to the safe, efficient and reli- able operation of advanced energy systems. With recent advances in sensor development, it is now possible to push some level of decision making directly to computationally sophisticated sensors, rather than wait for data to arrive to a massive centralized location before a decision is made. This type of approach relies on networked sensors (called “agents” from here on) to actively collect and process data, and provide key control deci- sions to significantly improve both the quality/relevance of the collected data and the as- sociating decision making. The technological bottlenecks for such sensor networks stem from a lack of mathematics and algorithms to manage the systems, rather than difficulties associated with building and deploying them. Indeed, traditional sensor coordination strategies do not provide adequate solutions for this problem. Passive data collection methods (e.g., large sensor webs) can scale to large systems, but are generally not suited to highly dynamic environments, such as ad- vanced energy systems, where crucial decisions may need to be reached quickly and lo- cally. Approaches based on local decisions on the other hand cannot guarantee that each agent performing its task (maximize an agent objective) will lead to good network wide solution (maximize a network objective) without invoking cumbersome coordination rou- tines. There is currently a lack of algorithms that will enable self-organization and blend the efficiency of local decision making with the system level guarantees of global decision making, particularly when the systems operate in dynamic and stochastic environments. In this work we addressed this critical gap and provided a comprehensive solution to the problem of sensor coordination to ensure the safe, reliable, and robust operation of advanced energy systems. The differentiating aspect of the proposed work is in shift- ing the focus towards “what to observe” rather than “how to observe” in large sensor networks, allowing the agents to actively determine both the structure of the network and the relevance of the information they are seeking to collect. In addition to providing an implicit coordination mechanism, this approach allows the system to be reconfigured in response to changing needs (e.g., sudden external events requiring new responses) or changing sensor network characteristics (e.g., sudden changes to plant condition). Outcome Summary: All milestones associated with this project have been completed. In particular, private sensor objective functions were developed which are aligned with the global objective function, sensor effectiveness has been improved by using “sensor teams,” system efficiency has been improved by 30% using difference evaluation func- tions, we have demonstrated system reconfigurability for 20% changes in system con- ditions, we have demonstrated extreme scalability of our proposed algorithm, we have demonstrated that sensor networks can overcome disruptions of up to 20% in network conditions, and have demonstrated system reconfigurability to 20% changes in system conditions in hardware-based simulations. This final report summarizes how each of these milestones was achieved, and gives insight into future research possibilities past the work which has been completed. The following publications support these milestones [6, 8, 9, 10, 16, 18, 19].