National Library of Energy BETA

Sample records for d-3 ement cd-4

  1. The UNEP project CD4CDM Guidebook to

    E-Print Network [OSTI]

    months, with more than 1,700 projects in the pipeline by March 2007. However, CDM project development numerous CDM project concepts never materialise. This has been the case especially for Africa and for otherThe UNEP project CD4CDM Guidebook to Financing CDM Projects #12;Guidebook to Financing CDM Projects

  2. Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells

    E-Print Network [OSTI]

    Ploegh, Hidde

    Although it has long been known that human CD4+ T cells can express functional class II MHC molecules, the role of lysosomal proteases in the T cell class II MHC processing and presentation pathway is unknown. Using CD4+ ...

  3. Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells

    E-Print Network [OSTI]

    Babu, M. Madan

    Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells Daniel Hebenstreit1 , Andrew Deonarine1 , M Madan Babu and Sarah A Teichmann CD4+ T cells play key roles in orchestrating adaptive immune responses, and are a popular model for mammalian cell differentiation. While immune

  4. The role of Erk MAPK pathway in CD4 T cell proliferation and differentiation

    E-Print Network [OSTI]

    Chang, Chiung-Fang

    2011-01-01

    B. (2010). Key role of ERK pathway signaling in lupus.and Hedrick, S.M. The role of Erk MAPK pathway in CD4 T cellTHE DISSERTATION The role of Erk MAPK pathway in CD4 T cell

  5. CD4+ T cell responses to myelin autoantigens: activation, memory and tolerance 

    E-Print Network [OSTI]

    Chung, Chen-Yen

    2009-01-01

    Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T cell mediated autoimmune disease of the central nervous system and shares many characteristics with multiple sclerosis (MS). Induction of EAE is mediated by ...

  6. Intersecting D3-D3' system at finite temperature

    E-Print Network [OSTI]

    Cottrell, William; Hashimoto, Akikazu; Loveridge, Andrew; Pettengill, Duncan

    2015-01-01

    We analyze the embedding of probe D3'-brane in the background of $N$ D3-branes at finite temperature, oriented such that they overlap in 1+1 dimensions. As the distance between the D3'-brane and the D3 brane is varied, we find solutions that appear to intersect the horizon. We find that this brane bends logarithmically, making the precise definition of the distance separating the D3 and the D3' brane scale dependent. We also consider the embedding of a probe M5-brane in the background of $N$ M2-branes at finite temperature, for which the logarithmic bending is absent. These systems appear to open a path to probe physics near and behind the black hole horizon in a strictly field theoretic framework.

  7. Correlated energy disposal and scattering dynamics of the Cl CD4(m3 2) reaction

    E-Print Network [OSTI]

    Zare, Richard N.

    Correlated energy disposal and scattering dynamics of the Cl þ CD4(m3 ¼ 2) reaction HANS A-of-flight spectrometer. After preparing the first overtone of the antisymmetric stretch (3 ¼ 2) with direct IR excitation to the stretch­bend combination (11 121 1) band. The product correlated energy disposal and the scattering

  8. A decrease of circulating CD4? T cells in Attwater's prairie chickens infected with reticuloendotheliosis virus 

    E-Print Network [OSTI]

    Ferro, Pamela Joyce Bloomer

    2001-01-01

    of this project was to develop a method to monitor CD4? and CD8? T cells in prairie chickens and to determine if there was an alteration in the number of circulating T cells associated with REV infection in prairie chickens. A panel of anti-chicken monoclonal...

  9. Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Moody, M.  Anthony; Gao, Feng; Gurley, Thaddeus  C.; Amos, Joshua  D.; Kumar, Amit; Hora, Bhavna; Marshall, Dawn  J.; Whitesides, John  F.; Xia, Shi-Mao; Parks, Robert; et al

    2015-09-09

    The third variable (V3) loop and the CD4 binding site (CD4bs) of the viral envelope are frequently targeted by neutralizing antibodies (nAbs) in HIV-1-infected individuals. In chronic infection, virus escape mutants repopulate the plasma and V3 and CD4bs nAbs emerge that can neutralize heterologous tier 1 easy-to-neutralize, but not tier 2 difficult-to-neutralize HIV-1 isolates. However, neutralization sensitivity of autologous plasma viruses to this type of nAb response has not been studied. We describe the development and evolution in vivo of antibodies distinguished by their target specificity for V3and CD4bs epitopes on autologous tier 2 viruses but not on heterologous tiermore »2 viruses. A surprisingly high fraction of autologous circulating viruses was sensitive to these antibodies. These findings demonstrate a role for V3 and CD4bs antibodies in constraining the native envelope trimer in vivo to a neutralization-resistant phenotype, explaining why HIV-1 transmission generally occurs by tier 2 neutralization-resistant viruses.« less

  10. Molecular mechanisms of immunosuppressive effects of dietary n-3 pufa, curcumin and limonin on murine cd4+ t cells 

    E-Print Network [OSTI]

    Kim, Wooki

    2009-05-15

    The molecular mechanisms of putative anti-inflammatory nutrients, i.e., fish oil, curcumin and limonin, were investgated with respect to CD4+ T cell function. Initially, using a DO11.10 mouse model which exhibits a transgenic T cell receptor...

  11. Uplifting and Inflation with D3 Branes

    E-Print Network [OSTI]

    Cliff P. Burgess; James M. Cline; Keshav Dasgupta; Hassan Firouzjahi

    2006-10-30

    Back-reaction effects can modify the dynamics of mobile D3 branes moving within type IIB vacua, in a way which has recently become calculable. We identify some of the ways these effects can alter inflationary scenarios, with the following three results: (1) By examining how the forces on the brane due to moduli-stabilizing interactions modify the angular motion of D3 branes moving in Klebanov-Strassler type throats, we show how previous slow-roll analyses can remain unchanged for some brane trajectories, while being modified for other trajectories. These forces cause the D3 brane to sink to the bottom of the throat except in a narrow region close to the D7 brane, and do not ameliorate the \\eta-problem of slow roll inflation in these throats; (2) We argue that a recently-proposed back-reaction on the dilaton field can be used to provide an alternative way of uplifting these compactifications to Minkowski or De Sitter vacua, without the need for a supersymmetry-breaking anti-D3 brane; and (3) by including also the D-term forces which arise when supersymmetry-breaking fluxes are included on D7 branes we identify the 4D supergravity interactions which capture the dynamics of D3 motion in D3/D7 inflationary scenarios. The form of these potentials sheds some light on recent discussions of how symmetries constrain D term interactions in the low-energy theory.

  12. Id1 expression promotes peripheral CD4{sup +} T cell proliferation and survival upon TCR activation without co-stimulation

    SciTech Connect (OSTI)

    Liu, Chen; Jin, Rong [Department of Immunology, Peking University Health Science Center, Beijing (China)] [Department of Immunology, Peking University Health Science Center, Beijing (China); Wang, Hong-Cheng [Oklahoma Medical Research Foundation, Oklahoma City, OK (United States)] [Oklahoma Medical Research Foundation, Oklahoma City, OK (United States); Tang, Hui; Liu, Yuan-Feng; Qian, Xiao-Ping; Sun, Xiu-Yuan; Ge, Qing [Department of Immunology, Peking University Health Science Center, Beijing (China)] [Department of Immunology, Peking University Health Science Center, Beijing (China); Sun, Xiao-Hong, E-mail: sunx@omrf.org [Oklahoma Medical Research Foundation, Oklahoma City, OK (United States)] [Oklahoma Medical Research Foundation, Oklahoma City, OK (United States); Zhang, Yu, E-mail: zhangyu007@bjmu.edu.cn [Department of Immunology, Peking University Health Science Center, Beijing (China)] [Department of Immunology, Peking University Health Science Center, Beijing (China)

    2013-06-21

    Highlights: •Id1 expression enables naïve T cell proliferation without anti-CD28 co-stimulation. •Id1 expression facilitates T cells survival when stimulated with anti-CD3. •Elevation of IL-2 production by Id1 contributes increased proliferation and survival. •Id1 potentiates NF-?B activation by anti-CD3 stimulation. -- Abstract: Although the role of E proteins in the thymocyte development is well documented, much less is known about their function in peripheral T cells. Here we demonstrated that CD4 promoter-driven transgenic expression of Id1, a naturally occurring dominant-negative inhibitor of E proteins, can substitute for the co-stimulatory signal delivered by CD28 to facilitate the proliferation and survival of naïve CD4{sup +} cells upon anti-CD3 stimulation. We next discovered that IL-2 production and NF-?B activity after anti-CD3 stimulation were significantly elevated in Id1-expressing cells, which may be, at least in part, responsible for the augmentation of their proliferation and survival. Taken together, results from this study suggest an important role of E and Id proteins in peripheral T cell activation. The ability of Id proteins to by-pass co-stimulatory signals to enable T cell activation has significant implications in regulating T cell immunity.

  13. Excitation functions for the reactions of Ar^+ with CH4, CD4, and CH2D2

    E-Print Network [OSTI]

    Wyatt, J. R.; Strattan, L. W.; Chivalak, S.; Hierl, Peter M.

    1975-01-01

    )-(3) are plotted in Figs. 6 and 7. It was found that the over-all shape of the excitation functions for Reactions (1)-(3) could be described rea­ sonably well (sQe Figs. 6 and 7) by a simple expreSSion of the general form {o if E"'Eo uR(E)= A(E_Eo)Be_C(E-EO... to IP: 129.237.46.100 On: Mon, 15 Sep 2014 13:25:50 Wyatt, Strattan, Chivalak, and Hierl: Reactions of Ar+ with CH4 , CD4 , and CH2 D2 4589 (0) 0.25 0 0 C\\l E u <:e I 0 cr b (b) C\\l E u <:e I Q cr b 0.15 0.0 o. FIG. 7. Integral...

  14. Role of the frequency of blood CD4{sup +} CXCR5{sup +} CCR6{sup +} T cells in autoimmunity in patients with Sjoegren's syndrome

    SciTech Connect (OSTI)

    Li, Xue-yi; Wu, Zhen-biao; Ding, Jin; Zheng, Zhao-hui [Department of Clinical Immunology, State key Discipline of Cell Biology, Xi-jing Hospital, Fourth Military Medical University, Shaanxi Province (China)] [Department of Clinical Immunology, State key Discipline of Cell Biology, Xi-jing Hospital, Fourth Military Medical University, Shaanxi Province (China); Li, Xiao-yan [Department of Endocrine and Metabolic Diseases, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi Province (China)] [Department of Endocrine and Metabolic Diseases, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi Province (China); Chen, Li-na [Department of Clinical Immunology, State key Discipline of Cell Biology, Xi-jing Hospital, Fourth Military Medical University, Shaanxi Province (China)] [Department of Clinical Immunology, State key Discipline of Cell Biology, Xi-jing Hospital, Fourth Military Medical University, Shaanxi Province (China); Zhu, Ping, E-mail: zhuping@fmmu.edu.cn [Department of Clinical Immunology, State key Discipline of Cell Biology, Xi-jing Hospital, Fourth Military Medical University, Shaanxi Province (China)] [Department of Clinical Immunology, State key Discipline of Cell Biology, Xi-jing Hospital, Fourth Military Medical University, Shaanxi Province (China)

    2012-06-01

    Highlights: Black-Right-Pointing-Pointer The frequency of CD4{sup +} CXCR5{sup +} CCR6{sup +} T cells increased in pSS patients and positively correlated with autoantibodies in the blood. Black-Right-Pointing-Pointer CD4{sup +} CXCR5{sup +} CCR6{sup +} T cells in blood invariably coexpressed PD-1, ICOS, CD40L, Bcl-6 and secreted IL-21 after stimulated by PHA. Black-Right-Pointing-Pointer CD4{sup +} CXCR5{sup +} CCR6{sup +} Tfh cells in blood may be suitable biomarkers for the evaluation of the active immune stage of pSS patients. -- Abstract: The blood CD4{sup +} CXCR5{sup +} T cells, known as 'circulating' Tfh, have been shown to efficiently induce naieve B cells to produce immunoglobulin. They play an important role in certain autoimmune diseases. In the present study, we show for the first time that the frequency of CD4{sup +} CXCR5{sup +} T cells is increased in pSS patients and positively correlated with autoantibodies in the blood. The concentration of Th17-like subsets (CD4{sup +} CXCR5{sup +} CCR6{sup +}) in pSS patients was found to be significantly higher than in healthy controls. Functional assays showed that activated Th17-like subtypes in the blood display the key features of Tfh cells, including invariably coexpressed PD-1, ICOS, CD40L and IL-21. Th17 subsets were found to highly express Bcl-6 protein and Th1 and Th2 were not. Bcl-6 is believed to be a master transforming factor for Tfh cell differentiation and facilitate B cell proliferation and somatic hypermutation within the germinal center. These data indicate that Th17 subsets of CD4{sup +} CXCR5{sup +} T cells in the blood may participate in the antibody-related immune responses and that high frequency of CD4{sup +} CXCR5{sup +} CCR6{sup +} Tfh cells in blood may be suitable biomarkers for the evaluation of the active immune stage of pSS patients. It might provide insights into the pathogenesis and perhaps help researchers identify novel therapeutic targets for pSS.

  15. D3 website database | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department of EnergyCyrus Wadia About Us Cyrus Wadia -D3 website

  16. H + CD4 Abstraction Reaction Dynamics: Product Energy Partitioning Wenfang Hu, Gyo1rgy Lendvay, Diego Troya,# George C. Schatz,*, Jon P. Camden,|

    E-Print Network [OSTI]

    Zare, Richard N.

    H + CD4 Abstraction Reaction Dynamics: Product Energy Partitioning Wenfang Hu, Gyo1rgy LendvayVember 12, 2005 This paper presents experimental and theoretical studies of the product energy partitioning of the energy appears in product translation at energies just above the reactive threshold; however, HD

  17. Regression coefficient maps showing that Nadir CD4+ count is correlated with regional white matter volumes (FDR q=0.05, critical P=0.03)

    E-Print Network [OSTI]

    Thompson, Paul

    Results Regression coefficient maps showing that Nadir CD4+ count is correlated with regional white matter volumes (FDR q=0.05, critical P=0.03) Regression coefficient maps showing that NAA levels of neurodegeneration. At each voxel in the brain, multiple regression was used to assess associations between regional

  18. A Reinterpretation of the Mechanism of the Simplest Reaction at an -Hybridized Carbon Atom: H + CD4 f CD3 + HD

    E-Print Network [OSTI]

    Zare, Richard N.

    ,11 we measure the center of mass differential cross-section (DCS) of the CD3()0) products for Ecoll + CD4 f CD3 + HD Jon P. Camden, Hans A. Bechtel, Davida J. Ankeny Brown, Marion R. Martin, Richard N, but the small reaction cross-section has made state-to- state resolved dynamics experiments difficult, and few

  19. A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state

    E-Print Network [OSTI]

    2010-01-01

    found B6 CD93 ?/? and B6. NOD Idd13 mice to be susceptibleCD4 + NKT cells. Keywords NOD mice . Idd13 . NZB/W F1 mice .Abbreviations BM TR MZ iNKT cell NOD DN CD4SP Idd alpha-

  20. Evolution of the D3-brane for dynamical embeddings

    E-Print Network [OSTI]

    Pawel Gusin; Jerzy Warczewski

    2008-09-03

    The Dirac-Born-Infeld (DBI) action of the 3-dimensional brane for its dynamical embeddings and the gauge fields has been studied. The evolution of both the D3-brane and the ambient space has been obtained. For the special constraint put on the transverse coordinates a family of the contracting and expanding spaces has been found.

  1. 4000 cm D2 MAGNET D3 MAGNET

    E-Print Network [OSTI]

    Tokyo, University of

    MONITOR D2 MAGNET S2 STEERING HORIZONTAL BEAM PIPE SUPER-KAMIOKANDE TANK 1350mm LEAD SHIELD LEAD SHIELD SUPER-KAMIOKANDE TANK C4 COLLIMATOR Q1 QUADROPOLE M2 BEAM MONITOR D3 BENDING MAGNET Q2 QUADRO- POLE

  2. Deconstructing and Restyling D3 Visualizations Jonathan Harper

    E-Print Network [OSTI]

    O'Brien, James F.

    . of her webpage. A viewer might prefer to view a pie chart in the form of a bar chart so that it is easier. Author Keywords Visualization, chart understanding, restyling, D3 ACM Classification Keywords H.5 of a visualization. For instance, a colorblind viewer may need to shift the red and green marks in a chart to colors

  3. [Cu(pyrazine-2-carboxylate)2]2Cd4I8: unprecedented 1-D serpentine inorganic chains and regular 2-D metalorganic square grids in a 3-D

    E-Print Network [OSTI]

    zur Loye, Hans-Conrad

    the design and synthesis of new hybrid organic­ inorganic materials to become a prolific domain in the field[Cu(pyrazine-2-carboxylate)2]2Cd4I8: unprecedented 1-D serpentine inorganic chains and regular 2-D are also known: Zubieta and coworkers13 have reported the synthesis of anionic 1-D oxide chains covalently

  4. Taming Supersymmetric Defects in 3d-3d Correspondence

    E-Print Network [OSTI]

    Gang, Dongmin; Romo, Mauricio; Yamazaki, Masahito

    2015-01-01

    We study knots in 3d Chern-Simons theory with complex gauge group $SL(N,\\mathbb{C})$, in the context of its relation with 3d $\\mathcal{N}=2$ theory (the so-called 3d-3d correspondence). The defect has either co-dimension 2 or co-dimension 4 inside the 6d $(2,0)$ theory, which is compactified on a 3-manifold $\\hat{M}$. We identify such defects in various corners of the 3d-3d correspondence, namely in 3d $SL(N,\\mathbb{C})$ Chern-Simons theory, in 3d $\\mathcal{N}=2$ theory, in 5d $\\mathcal{N}=2$ super Yang-Mills theory, and in the M-theory holographic dual. We can make quantitative checks of the 3d-3d correspondence by computing partition functions at each of these theories. This Letter is a companion to a longer paper, which contains more details and more results.

  5. BPS Soliton Solutions of a D3-brane Action

    E-Print Network [OSTI]

    John H. Schwarz

    2014-07-07

    The world-volume action of a probe D3-brane in $AdS_5 \\times S^5$ with $N$ units of flux has the field content, symmetries, and dualities of the $U(1)$ factor of ${\\cal N} = 4$ $U(N+1)$ super Yang--Mills theory, spontaneously broken to $U(N) \\times U(1)$ by being on the Coulomb branch, with the massive fields integrated out. Thus, it might be the exact effective action (a highly effective action), or else a useful approximation to it. We construct an $SL(2,Z)$ multiplet of BPS soliton solutions of the D3-brane action and show that in the $N=1$ case they correspond to the electrically charged states that have been integrated out as well as magnetic monopoles and dyons. Their charges are uniformly spread on a spherical surface, a soliton bubble, which can be interpreted as a phase boundary. This picture is consistent with previous results in the string theory and field theory literature.

  6. 2D/3D registration algorithm for lung brachytherapy

    SciTech Connect (OSTI)

    Zvonarev, P. S.; Farrell, T. J.; Hunter, R.; Wierzbicki, M.; Hayward, J. E.; Sur, R. K.

    2013-02-15

    Purpose: A 2D/3D registration algorithm is proposed for registering orthogonal x-ray images with a diagnostic CT volume for high dose rate (HDR) lung brachytherapy. Methods: The algorithm utilizes a rigid registration model based on a pixel/voxel intensity matching approach. To achieve accurate registration, a robust similarity measure combining normalized mutual information, image gradient, and intensity difference was developed. The algorithm was validated using a simple body and anthropomorphic phantoms. Transfer catheters were placed inside the phantoms to simulate the unique image features observed during treatment. The algorithm sensitivity to various degrees of initial misregistration and to the presence of foreign objects, such as ECG leads, was evaluated. Results: The mean registration error was 2.2 and 1.9 mm for the simple body and anthropomorphic phantoms, respectively. The error was comparable to the interoperator catheter digitization error of 1.6 mm. Preliminary analysis of data acquired from four patients indicated a mean registration error of 4.2 mm. Conclusions: Results obtained using the proposed algorithm are clinically acceptable especially considering the complications normally encountered when imaging during lung HDR brachytherapy.

  7. Uplifting the baryonic branch: a test for backreacting anti-D3-branes

    E-Print Network [OSTI]

    Anatoly Dymarsky; Stefano Massai

    2013-09-30

    Placing D3 or anti-D3-branes at the tip of the Klebanov-Strassler background results in uplifting the baryonic branch of the moduli space of the dual field theory. In this paper we derive a mass formula for the scalar particle associated with the motion along the baryonic branch, from both open and closed string points of view. We show that both methods give the same mass at linear order in number of (anti)D3-branes, thus providing a comprehensive check for the recently found linearized supergravity solution describing backreacting anti-D3-branes at the tip.

  8. D3: Data-centric Data Dissemination in Wireless Sensor Networks

    E-Print Network [OSTI]

    Langendoen, Koen

    D3: Data-centric Data Dissemination in Wireless Sensor Networks Maarten Ditzel Netherlands, called D3 (Data-centric Data Dissemination). The method combines the advantages of data-centric routing much energy or poorly support multi-hop networks. In [8] and [9] the authors propose a new data-centric

  9. Ubiquitination and degradation of the hominoid-specific oncoprotein TBC1D3 is regulated by protein palmitoylation

    SciTech Connect (OSTI)

    Kong, Chen; Lange, Jeffrey J.; Samovski, Dmitri [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States)] [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States); Su, Xiong [Department of Internal Medicine, Center for Human Nutrition Washington University School of Medicine, St. Louis, MO 63110 (United States)] [Department of Internal Medicine, Center for Human Nutrition Washington University School of Medicine, St. Louis, MO 63110 (United States); Liu, Jialiu [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States)] [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States); Sundaresan, Sinju [Department of Internal Medicine, Center for Human Nutrition Washington University School of Medicine, St. Louis, MO 63110 (United States)] [Department of Internal Medicine, Center for Human Nutrition Washington University School of Medicine, St. Louis, MO 63110 (United States); Stahl, Philip D., E-mail: pstahl@wustl.edu [Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110 (United States)

    2013-05-03

    Highlights: •Hominoid-specific oncogene TBC1D3 is targeted to plasma membrane by palmitoylation. •TBC1D3 is palmitoylated on two cysteine residues: 318 and 325. •TBC1D3 palmitoylation governs growth factors-induced TBC1D3 degradation. •Post-translational modifications may regulate oncogenic properties of TBC1D3. -- Abstract: Expression of the hominoid-specific oncoprotein TBC1D3 promotes enhanced cell growth and proliferation by increased activation of signal transduction through several growth factors. Recently we documented the role of CUL7 E3 ligase in growth factors-induced ubiquitination and degradation of TBC1D3. Here we expanded our study to discover additional molecular mechanisms that control TBC1D3 protein turnover. We report that TBC1D3 is palmitoylated on two cysteine residues: 318 and 325. The expression of double palmitoylation mutant TBC1D3:C318/325S resulted in protein mislocalization and enhanced growth factors-induced TBC1D3 degradation. Moreover, ubiquitination of TBC1D3 via CUL7 E3 ligase complex was increased by mutating the palmitoylation sites, suggesting that depalmitoylation of TBC1D3 makes the protein more available for ubiquitination and degradation. The results reported here provide novel insights into the molecular mechanisms that govern TBC1D3 protein degradation. Dysregulation of these mechanisms in vivo could potentially result in aberrant TBC1D3 expression and promote oncogenesis.

  10. Abstract. Background: 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] is the biological active form of vitamin D. Its

    E-Print Network [OSTI]

    of vitamin D. Its antiproliferative capacities make it a potential drug to treat diseases such as cancer1112. Conclusion: The superagonistic vitamin D analog WY1112 induces the same set of genes as 1,25-(OH of producing the major portion of vitamin D3 itself by photosynthesis in the skin. Under the influence of UV

  11. Re-evaluation of the Vitamin D3 Requirement for Growing Chickens 

    E-Print Network [OSTI]

    Leyva Jimenez, Hector Enrique

    2015-07-24

    Three experiments were conducted with the purpose of re-evaluating the vitamin D3 requirement of growing chickens. Due to intense genetic selection in the poultry industry, it is probable that modern strains have altered ...

  12. A 3D-3C Reflection Seismic Survey and Data Integration to Identify...

    Open Energy Info (EERE)

    A 3D-3C Reflection Seismic Survey and Data Integration to Identify the Seismic Response of Fractures and Permeable Zones Over a Known Geothermal Resource at Soda Lake, Churchill...

  13. Uptake of donor lymphocytes treated with 8-methoxypsoralen and ultraviolet A light by recipient dendritic cells induces CD4{sup +}CD25{sup +}Foxp3{sup +} regulatory T cells and down-regulates cardiac allograft rejection

    SciTech Connect (OSTI)

    Zheng, De-Hua; Dou, Li-Ping; Wei, Yu-Xiang; Du, Guo-Sheng; Zou, Yi-Ping; Song, Ji-Yong; Zhu, Zhi-Dong; Cai, Ming; Qian, Ye-Yong; Shi, Bing-Yi

    2010-05-14

    Extracorporeal photopheresis (ECP) is an effective immunomodulatory therapy and has been demonstrated to be beneficial for graft-vs-host disease and solid-organ allograft rejection. ECP involves reinfusion of a patient's autologous peripheral blood leukocytes treated ex vivo with 8-methoxypsoralen and UVA light radiation (PUVA). Previous studies focused only on ECP treatment of recipient immune cells. Our study is the first to extend the target of ECP treatment to donor immune cells. The results of in vitro co-culture experiments demonstrate uptake of donor PUVA-treated splenic lymphocytes (PUVA-SPs) by recipient immature dendritic cells (DCs). Phagocytosis of donor PUVA-SPs does not stimulate phenotype maturation of recipient DCs. In the same co-culture system, donor PUVA-SPs enhanced production of interleukin-10 and interferon-{gamma} by recipient DCs and impaired the subsequent capability of recipient DCs to stimulate recipient naive T cells. Phagocytosis of donor PUVA-SP (PUVA-SP DCs) by recipient DCs shifted T-cell responses in favor of T helper 2 cells. Infusion of PUVA-SP DCs inhibited cardiac allograft rejection in an antigen-specific manner and induced CD4{sup +}CD25{sup high}Foxp3{sup +} regulatory T cells. In conclusion, PUVA-SP DCs simultaneously deliver the donor antigen and the regulatory signal to the transplant recipient, and thus can be used to develop a novel DC vaccine for negative immune regulation and immune tolerance induction.

  14. Project Transition/Closeout (CD-4)

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2008-09-24

    This Guide is written for the federal project director ensuring that processes progress smoothly and that projects meet asset management goals and financial closure requirements of DOE.

  15. Polymeric-lens-embedded 2D/3D switchable display with dramatically reduced crosstalk

    E-Print Network [OSTI]

    Wu, Shin-Tson

    OCIS codes: (110.1080) Active or adaptive optics; (110.0110) Imaging systems; (100.6890) Three and mobile displays. A critical element in the 2D/3D switchable display is the adaptive liquid crystal (LC optimization by modifying the layout of light blocking components [21], and us- ing triplet structures

  16. IAC-05-D3.3.03 SUSTAINABILITY IN SYSTEM ARCHITECTURES

    E-Print Network [OSTI]

    de Weck, Olivier L.

    performance. Sustainable system architectures however need to be affordable, ensure delivery of valueIAC-05-D3.3.03 SUSTAINABILITY IN SYSTEM ARCHITECTURES THROUGH RECONFIGURABILITY: A CASE STUDY be on the order of 35% while risk of non-performance can be reduced to 1%. The cost of reconfiguration however

  17. Hybrid Tetramers Reveal Elements of Cooperativity in Escherichia coli D-3-Phosphoglycerate Dehydrogenase*

    E-Print Network [OSTI]

    Grant, Gregory

    Hybrid Tetramers Reveal Elements of Cooperativity in Escherichia coli D-3-Phosphoglycerate is a tetramer of identical subunits that is inhibited when L-serine binds at allosteric sites between subunits- taining a mutation that eliminates serine binding, pro- duces hybrid tetramers that can be separated

  18. 8D.3 INVESTIGATING CONVECTIVE ELEMENTS IN A HIGH RESOLUTION SIMULATION OF HURRICANE OPAL (1995)

    E-Print Network [OSTI]

    Wilhelmson, Robert

    1995-01-01

    8D.3 INVESTIGATING CONVECTIVE ELEMENTS IN A HIGH RESOLUTION SIMULATION OF HURRICANE OPAL (1995. INTRODUCTION Numerous studies have investigated the intensity and track of Hurricane Opal in 1995, an event the convective scale behavior of the hurricane. This is of particular interest because Hurricane Opal

  19. Efficacy of high-concentration tacalcitol ointment in psoriasis vulgaris after changing from other high-concentration vitamin D3 ointments

    E-Print Network [OSTI]

    Abe, Masatoshi; Syuto, Tomoko; Ishibuchi, Hirohisa; Sogabe, Yoko; Yokoyama, Yoko; Ishikawa, Osamu

    2008-01-01

    D3, a novel active form of vitamin D3 with high activity forIqbal SJ, Hutchinson PE. Vitamin D analogues in psoriasis:other high-concentration vitamin D3 ointments Masatoshi Abe

  20. 2D?3D polycatenated and 3D?3D interpenetrated metal–organic frameworks constructed from thiophene-2,5-dicarboxylate and rigid bis(imidazole) ligands

    SciTech Connect (OSTI)

    Erer, Hakan; Ye?ilel, Okan Zafer; Ar?c?, Mürsel; Keskin, Seda; Büyükgüngör, Orhan

    2014-02-15

    Hydrothermal reactions of rigid 1,4-bis(imidazol-1-yl)benzene (dib) and 1,4-bis(imidazol-1-yl)-2,5-dimethylbenzene (dimb) with deprotonated thiophene-2,5-dicarboxylic acid (H{sub 2}tdc) in the presence of Zn(II) and Cd(II) salts in H{sub 2}O produced three new metal–organic frameworks, namely, [Zn(µ-tdc)(H{sub 2}O)(µ-dib)]{sub n} (1), [Cd(µ-tdc)(H{sub 2}O)(µ-dib)]{sub n} (2), and ([Cd{sub 2}(µ{sub 3}-tdc){sub 2}(µ-dimb){sub 2}]·(H{sub 2}O)){sub n}(3). These MOFs were characterized by FT-IR spectroscopy, elemental, thermal (TG, DTA, DTG and DSC), and single-crystal X-ray diffraction analyses. Isomorphous complexes 1 and 2 reveal polycatenated 2D+2D?3D framework based on an undulated (4,4)-sql layer. Complex 3 exhibits a new 4-fold interpenetrating 3D framework with the point symbol of 6{sup 6}. Molecular simulations were used to assess the potentials of the complexes for H{sub 2} storage application. Moreover, these coordination polymers exhibit blue fluorescent emission bands in the solid state at room temperature. - Graphical abstract: In this study, hydrothermal reactions of rigid 1,4-bis(imidazol-1-yl)benzene (dib) and 1,4-bis(imidazol-1-yl)-2,5-dimethylbenzene (dimb) with deprotonated thiophene-2,5-dicarboxylic acid (H{sub 2}tdc) in the presence of Zn(II) and Cd(II) salts in H{sub 2}O produced three new metal–organic frameworks. Isomorphous complexes 1 and 2 reveal polycatenated 2D+2D?3D framework based on an undulated (4,4)-sql layer. Complex 3 exhibits a new 4-fold interpenetrating 3D framework with the point symbol of 6{sup 6}. Molecular simulations were used to assess the potentials of the complexes for H{sub 2} storage application. These coordination polymers exhibit blue fluorescent emission bands in the solid state at room temperature. Display Omitted - Highlights: • Complexes 1 and 2 display polycatenated 2D+2D?3D framework. • Complex 3 exhibits a new 4-fold interpenetrating 3D framework. • Complex 1 adsorbs the highest amount of H{sub 2} at 100 bar and 298 K. • Complexes display blue fluorescent emission bands.

  1. Analysis results from the Los Alamos 2D/3D program

    SciTech Connect (OSTI)

    Boyack, B.E.; Cappiello, M.W.; Harmony, S.C.; Shire, P.R.; Siebe, D.A.

    1987-01-01

    Los Alamos National Laboratory is a participant in the 2D/3D program. Activities conducted at Los Alamos National Laboratory in support of 2D/3D program goals include analysis support of facility design, construction, and operation; provision of boundary and initial conditions for test-facility operations based on analysis of pressurized water reactors; performance of pretest and posttest predictions and analyses; and use of experimental results to validate and assess the single- and multi-dimensional, nonequilibrium features in the Transient Reactor Analysis Code (TRAC). During fiscal year 1987, Los Alamos conducted analytical assessment activities using data from the Slab Core Test Facility, The Cylindrical Core Test Facility, and the Upper Plenum Test Facility. Finally, Los Alamos continued work to provide TRAC improvements. In this paper, Los Alamos activities during fiscal year 1987 will be summarized; several significant accomplishments will be described in more detail to illustrate the work activities at Los Alamos.

  2. E~ S·D3 Weldon Spring Site Environmental Repon lor Calendar Year 2002

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouth DakotaRobbins and700, 1.Reports1E~ S·D3 Weldon Spring Site

  3. Normalized%Infection CD4CCR5 Normalized%Infection CD4CCR5

    E-Print Network [OSTI]

    Levine, Alex J.

    , Tom Chou2 , Katharina Borm3 , Jasminka Sterjovski3,4 , Paul R Gorry3,4,5 and Benhur Lee1,6* Abstract

  4. Analysis results from the Los Alamos 2D/3D program

    SciTech Connect (OSTI)

    Boyack, B.E.; Cappiello, M.W.; Stumpf, H.; Shire, P.; Gilbert, J.; Hedstrom, J.

    1986-01-01

    Los Alamos National Laboratory is a participant in the 2D/3D program. Activities conducted at Los Alamos National Laboratory in support of 2D/3D program goals include analysis support of facility design, construction, and operation; provision of boundary and initial conditions for test facility operations based on analysis of pressurized water reactors; performance of pretest and posttest predictions and analyses; and use of experimental results to validate and assess the single- and multidimensional nonequilibrium features in the Transient Reactor Analysis Code (TRAC). During Fiscal Year 1986, Los Alamos conducted analytical assessment activities using data from the Cylindrical Core Test Facility and the Slab Core Test Facility. Los Alamos also continued to provide support analysis for the planning of Upper Plenum Test Facility experiments. Finally, Los Alamos either completed or is currently working on three areas of TRAC modeling improvement. In this paper, Los Alamos activities during Fiscal Year 1986 are summarized; several significant accomplishments are described in more detail to illustrate the work activities at Los Alamos.

  5. Use of 2D/3D data for peak cladding temperature uncertainty studies

    SciTech Connect (OSTI)

    Boyack, B.E.

    1988-01-01

    In August 1988, the Nuclear Regulatory Commission (NRC) approved the final version of a revised rule on the acceptance of emergency core cooling systems. The revised rule allows emergency core cooling system analysis based on best-estimate methods, provided uncertainties in the prediction of prescribed acceptance limits are quantified and reported. To support the revised rule, the NRC developed the Code Scaling, Applicability, and Uncertainty (CSAU) evaluation methodology. Data from the 2D/3D program have been used in a demonstration of the CSAU methodology in two ways. First, the data were used to identify and quantify biases that are related to the implementation of selected correlations and models in the thermal-hydraulic systems code TRAC-PF1/MOD1 as it is used to calculate the demonstration transient, a large-break loss-of-coolant accident. Second, the data were used in a supportive role to provide insight into the accuracy of code calculations and to confirm conclusions that are drawn regarding specific CSAU studies. Examples are provided illustrating each of these two uses of 2D/3D data. 9 refs., 7 figs.

  6. arXiv:cond-mat/0503226v19Mar2005 Two Superconducting Phases in the d = 3 Hubbard Model

    E-Print Network [OSTI]

    Gozuacik, Devrim

    arXiv:cond-mat/0503226v19Mar2005 Two Superconducting Phases in the d = 3 Hubbard Model: Phase. The strong-coupling phase, on the other hand, has characteristics of BEC-type superconductivity, including

  7. Data:12a45141-7972-4ec8-a2dc-37fedc8133d3 | Open Energy Information

    Open Energy Info (EERE)

    ec8-a2dc-37fedc8133d3 No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic...

  8. 1D3V PIC simulation of propagation of relativistic electron beam in an inhomogeneous plasma

    E-Print Network [OSTI]

    Shukla, Chandrashekhar; Patel, Kartik

    2015-01-01

    A recent experimental observation has shown efficient transport of Mega Ampere of electron currents through aligned carbon nanotube arrays [Phys. Rev Letts. 108, 235005 (2012)]. The result was subsequently interpreted on the basis of suppression of the filamentation instability in an inhomogeneous plasma [Phys. Plasmas 21, 012108 (2014)]. This inhomogeneity forms as a result of the ionization of the carbon nanotubes. In the present work a full 1D3V Particle-in-Cell (PIC) simulations have been carried out for the propagation of relativistic electron beams (REB) through an inhomogeneous background plasma. The suppression of the filamentation instability, responsible for beam divergence, is shown. The simulation also confirms that in the nonlinear regime too the REB propagation is better when it propagates through a plasma whose density is inhomogeneous transverse to the beam. The role of inhomogeneity scale length, its amplitude and the transverse beam temperature etc., in the suppression of the instability is ...

  9. Fusion of Superalgebras and D=3, N=4 Quiver Gauge Theories

    E-Print Network [OSTI]

    Fa-Min Chen; Yong-Shi Wu

    2012-12-29

    For further investigating the underlying structures of the D=3, N=4 Chern-Simons-matter (CSM) theories, we suggest a new concept and procedure for "fusing" two superalgebras into a single new superalgebra. The starting superalgebras may be those used in the previous construction of the double-symplectic 3-algebras in the N=4 CSM theories: The bosonic parts of these two superalgebras share at least one simple factor or U(1) factor. We are able to provide two different methods to do the "fusion". Several explicit examples are presented to demonstrate the "fusion" procedure. We also generalize the "fusion" procedure so that more than two superaglebras can be fused into a single one, provided some conditions are satisfied. It is shown that two or more N=4 theories with different gauge groups may be associated with the same "fused" superalgebra.

  10. Diffusion of barium atoms in the 6s5d 3 DJ metastable levels and the 6s2 1

    E-Print Network [OSTI]

    Huennekens, John

    ) for the barium-helium system are compared with values calculated from published, theoretical barium-helium to be negligible. Thus the main loss mechanism of 6s5d 3 DJ state atoms out of the detection region is diffusion

  11. Remaining Sites Verification Package for 132-D-3, 1608-D Effluent Pumping Station, Waste Site Reclassification Form 2005-033

    SciTech Connect (OSTI)

    R. A. Carlson

    2006-05-09

    Decommissioning and demolition of the 132-D-3 site, 1608-D Effluent Pumping Station was performed in 1986. Decommissioning included removal of equipment, water, and sludge for disposal as radioactive waste. The at- and below-grade structure was demolished to at least 1 m below grade and the resulting rubble buried in situ. The area was backfilled to grade with at least 1 m of clean fill and contoured to the surrounding terrain. Residual concentrations support future land uses that can be represented by a rural-residential scenario and pose no threat to groundwater or the Columbia River based on RESRAD modeling.

  12. The influence of coronal EUV irradiance on the emission in the He I 10830 A and D3 multiplets

    E-Print Network [OSTI]

    R. Centeno; J. Trujillo Bueno; H. Uitenbroek; M. Collados

    2007-12-13

    Two of the most attractive spectral windows for spectropolarimetric investigations of the physical properties of the plasma structures in the solar chromosphere and corona are the ones provided by the spectral lines of the He I 10830 A and 5876 A (or D3) multiplets, whose polarization signals are sensitive to the Hanle and Zeeman effects. However, in order to be able to carry out reliable diagnostics, it is crucial to have a good physical understanding of the sensitivity of the observed spectral line radiation to the various competing driving mechanisms. Here we report a series of off-the-limb non-LTE calculations of the He I D3 and 10830 A emission profiles, focusing our investigation on their sensitivity to the EUV coronal irradiation and the model atmosphere used in the calculations. We show in particular that the intensity ratio of the blue to the red components in the emission profiles of the He I 10830 A multiplet turns out to be a good candidate as a diagnostic tool for the coronal irradiance. Measurements of this observable as a function of the distance to the limb and its confrontation with radiative transfer modeling might give us valuable information on the physical properties of the solar atmosphere and on the amount of EUV radiation at relevant wavelengths penetrating the chromosphere from above.

  13. CD4CDM Developments Romeo Pacudan PhD

    E-Print Network [OSTI]

    NEP Resubmission of revised project documents Are revisions needed? Assessment oftheproject documents usingthe National Evaluation Protocol (NEP) CDM Secreta

  14. Critical Decision 4 (CD-4) Approval Template | Department of...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    More Documents & Publications Example BCP Template Critical Decision 2 (CD-2) Approval Template SOW and Key Performance Parameters (KPP) Handbook Final Version 9-30-2014...

  15. DOE CD-4 Review of the MINERvA Project

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory of raregovAboutRecoveryplanningCoalSocialFrameworksNOWRegisterDOE CD-1/2/3a3b4

  16. Thermalization of fast cesium 5D3/2 atoms in collisions with ground-state cesium atoms A. P. Hickman,1

    E-Print Network [OSTI]

    Huennekens, John

    Thermalization of fast cesium 5D3/2 atoms in collisions with ground-state cesium atoms A. Marks,1 A atoms. Photodissociation of Cs2 molecules into ground- and excited-state cesium atoms has been observed + is the ground state of the cesium molecule and Cs2 * represents an excited state or states that can be reached

  17. The Multidimensional Filter Diagonalization Method II. Application to 2D Projections of 2D, 3D, and 4D NMR Experiments

    E-Print Network [OSTI]

    Mandelshtam, Vladimir A.

    The Multidimensional Filter Diagonalization Method II. Application to 2D Projections of 2D, 3D signals with up to four independent time variables. Direct projections of the multidimensional time- quency dimension (1). The increase in experiment time is a fair price to pay for the ability to tease out

  18. Seismic attribute analysis of the Upper Morrow Sandstone and the Arbuckle Group from 3D-3C seismic data at Cutter Field, southwest Kansas

    E-Print Network [OSTI]

    Redger, Clyde Austin

    2015-05-31

    these reservoirs with seismic methods is challenging for a number of geophysical reasons. This study investigates the accuracy with which analysis of post-stack 3D-3C seismic data can delineate Upper Morrow Sandstone reservoirs and predict Arbuckle Group rock...

  19. Heat Transfer -2 A pure platinum wire with diameter D = 3 mm and length L = 20 mm is placed outside on a day when air temperature

    E-Print Network [OSTI]

    Virginia Tech

    Heat Transfer - 2 A pure platinum wire with diameter D = 3 mm and length L = 20 mm is placed outside on a day when air temperature T = 10o C. The heat transfer coefficient at the wire's surface h equation that includes all heat transfer mechanisms involved in this problem. Write this energy balance

  20. Exotic magnetism on the quasi-FCC lattices of the d3 double perovskites La2NaB'O6 (B' = Ru, Os)

    SciTech Connect (OSTI)

    Aczel, Adam A; Baker, Peter J.; Bugaris, Dan; Yeon, Jeongho; Zur Loye, Hans-Conrad; Guidi, T.; Adroja, D. T.

    2014-01-01

    We find evidence for long-range and short-range ($\\zeta$~$=$~70~\\AA~at 4~K) incommensurate magnetic order on the quasi-face-centered-cubic (FCC) lattices of the monoclinic double perovskites La$_2$NaRuO$_6$ and La$_2$NaOsO$_6$ respectively. Incommensurate magnetic order on the FCC lattice has not been predicted by mean field theory, but may arise via a delicate balance of inequivalent nearest neighbour and next nearest neighbour exchange interactions. In the Ru system with long-range order, inelastic neutron scattering also reveals a spin gap $\\Delta$~$\\sim$~2.75~meV. Magnetic anisotropy is generally minimized in the more familiar octahedrally-coordinated $3d^3$ systems, so the large gap observed for La$_2$NaRuO$_6$ may result from the significantly enhanced value of spin-orbit coupling in this $4d^3$ material.

  1. u.s. DEPARThIENT OF ENERGY EERE PROJECT MANAG EMENT CENTER NFPA...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Inc. (BGI) would utilize DOE and cost share funds to (1) combine airborne full tensor gravity (FTG) and the z-axis tipper electromagnetic (ZTEM) deep penetrating, low frequency,...

  2. DEPARTlIiIENT OF ENERGY EERE PROJECT MAN AG EMENT CENTER NEPA DETERMINATION

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based| Department of EnergyCyrus Wadia About UsAwardDEPARTMENT OF THElAUIl)

  3. u.s. DEPARIUENI OF ENERGY EERE PROJECT MAN AG EMENT CENTER NEPA DETERMINATION

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobsMotion to Withdraw | DepartmentSuite 600, 1901THE6,test test1:

  4. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2 and 118-H-3 Solid Waste Burial Grounds

    SciTech Connect (OSTI)

    K. L. Vialetti

    2008-05-20

    This report presents the final hazard categorization for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  5. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    SciTech Connect (OSTI)

    T. J. Rodovsky

    2006-12-06

    This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  6. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    SciTech Connect (OSTI)

    T. J. Rodovsky

    2007-04-12

    This report presents the final hazard categorization (FHC) for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  7. Materials Data on Cd4OF6 (SG:137) by Materials Project

    SciTech Connect (OSTI)

    Kristin Persson

    2014-11-02

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  8. The mechanism of HIV-1 Nef-mediated downregulation of CD4

    E-Print Network [OSTI]

    Chaudhuri, Rittik

    2010-02-09

    ribosome entry site ITAM immunoreceptor tyrosine-based activation motif IVT in vitro transcription kDa kilodalton kT kilotesla LAMP1 lysosome associated membrane protein 1 LATE lithium acetate, tris, EDTA LB lysogeny broth Lck p56Lck LTNP long-term non...

  9. Materials Data on Ca9Cd4Bi9 (SG:55) by Materials Project

    SciTech Connect (OSTI)

    Kristin Persson

    2014-11-02

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  10. The role of Erk MAPK pathway in CD4 T cell proliferation and differentiation

    E-Print Network [OSTI]

    Chang, Chiung-Fang

    2011-01-01

    obtained using MHC-Class II tetramers to track LCMV-specificLCMV infection, fewer IFN? and tetramer positive cells wereErk2-deficient cells. The tetramer positive cells were able

  11. Supplement for: Characterizing the dynamics of CD4+ T cell priming within a

    E-Print Network [OSTI]

    Kirschner, Denise

    such that the number of DCs on the grid taper off after 33 hours Based Model S1.1.1 Environment Environment of our model is a 200 X 25, two dimensional grid that represents a 1/20 section of mouse lymph node (LN); each micro compartment of the grid (grid unit) is a 20 µm

  12. January_2007 Variation of CD4 count and percentage among women receiving antiretroviral

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , France. 3 Centre de Diagnostic et de Recherche sur le Sida (CeDReS), Centre Hospitalier Universitaire de and data management: Gérard Allou, Renaud Becquet, Katia Castetbon, Laurence Dequae-Merchadou, Charlotte

  13. Letters to Analytical Chemistry Microfluidic CD4+ T-Cell Counting Device Using

    E-Print Network [OSTI]

    Sia, Samuel K.

    syndrome (HIV/AIDS), which remains a major pandemic in both developed1 and developing countries,2 Amsterdam Avenue, New York, New York 10027, Department of Electrical Engineering, Columbia University, 1300, City University of Hong Kong, Kowloon, Hong Kong. § Department of Electrical Engineering, Columbia

  14. Integrated Biorefinery Research Facility (IBRF I-II) (Post CD-4), EERE, Aug

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematicsEnergy HeadquartersFuelBConservationEnergy5975-01 REPORT ONInstitutionalIntegrated2011 |

  15. C-340 Complex D&D Final Lessons Learned (Post CD-4), Environmental

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirley Ann JacksonDepartment|Marketing, LLCEfficiency | DepartmentEnergyof EnergyManagement

  16. Final Hazard Categorization and Auditable Safety Analysis for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2 and 118-H-3 Solid Waste Burial Grounds

    SciTech Connect (OSTI)

    T. J. Rodovsky

    2006-03-01

    This report presents the initial hazard categorization, final hazard categorization and auditable safety analysis for the remediation of the 118-D-1, 118-D-2, and 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site.

  17. Final Hazard Categorization for the Remediation of the 118-D-1, 118-D-2, 118-D-3, 118-H-1, 118-H-2, and 118-H-3 Solid Waste Burial Grounds

    SciTech Connect (OSTI)

    J.D. Ludowise

    2009-06-17

    This report presents the final hazard categorization for the remediation of the 118-D-1, 118-D-2, 118-D-3 Burial Grounds located within the 100-D/DR Area of the Hanford Site and the 118-H-1, 118-H-2, and 118-H-3 Burial Grounds located within the 100-H Area of the Hanford Site. A material at risk calculation was performed that determined the radiological inventory for each burial ground to be Hazard Category 3.

  18. n-3 Polyunsaturated Fatty Acids Alter Mouse CD4+ T Cell Activation by Modifying the Lipid Bilayer Properties 

    E-Print Network [OSTI]

    Hou, Tim Yu-Tien

    2014-12-05

    phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P2], which modulates actin remodeling, is perturbed by n-3 PUFA. Utilizing the transgenic Fat-1 mouse model that synthesizes n-3 PUFA de novo and enriches the plasma membrane with n-3 PUFA, and wild type (WT) mice fed...

  19. Immunosuppressive dietary n-3 polyunsaturated fatty acids differentially modulate costimulatory regulation of murine CD4+ T-cell function 

    E-Print Network [OSTI]

    Ly, Lan H.

    2005-02-17

    Consumption of fish oils (FO) enriched with the n-3 polyunsaturated fatty acids (PUFA), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), is beneficial to a variety of inflammatory disorders due, in part, to the alteration of membrane...

  20. Affinofile profiling: How efficiency of CD4/CCR5 usage impacts the biological and pathogenic phenotype of HIV

    E-Print Network [OSTI]

    Levine, Alex J.

    phenotype of HIV Kelechi Chikere a , Tom Chou b,c , Paul R. Gorry d,e,f , Benhur Lee a,c,g,n a Department

  1. Implicit Finite-Volume CMS2D/3D Models for Coastal Flow and Sediment Transport Weiming Wu1, Alejandro Sanchez2, Qianru Lin1, Lihwa Lin2, Julie D. Rosati2, Zeki Demirbilek2, Honghai Li2, Tanya M. Beck2, and Mitchell Brown2

    E-Print Network [OSTI]

    US Army Corps of Engineers

    Implicit Finite-Volume CMS2D/3D Models for Coastal Flow and Sediment Transport Weiming Wu1 and sediment transport model has been well tested by using laboratory and field measurement data and applied, Cross-shore Solvers: GMRES, BiCGSTAB, Gauss-Seidel Drying and wetting ­ "Freezing" dry nodes Multiple

  2. Library of high and mid-resolution spectra in the CaII H & K, H{alpha}, H{beta}, NaI D{1}, D{2}, and HeI D{3} line regions of F, G, K and M field stars

    E-Print Network [OSTI]

    D. Montes; E. L. Martin; M. J. Fernandez-Figueroa; M. Cornide; E. De Castro

    1996-09-30

    In this work we present spectroscopic observations centered in the spectral lines most widely used as optical indicators of chromospheric activity (H{alpha}, H{beta}, Ca II H & K, and He I D{3}) in a sample of F, G, K and M chromospherically inactive stars. The spectra have been obtained with the aim of providing a library of high and mid-resolution spectra to be used in the application of the spectral subtraction technique to obtain the active-chromosphere contribution to these lines in chromospherically active single and binary stars. This library can also be used for spectral classification purposes. A digital version with all the spectra is available via ftp and the World Wide Web (WWW) in both ASCII and FITS formats

  3. 10/28/14, 1:54 PMAbstract Print View Page 1 of 2http://www.abstractsonline.com/Plan/AbstractPrintView.aspx?mID=3527&sK...-50d3-406e-9abe-741db9e992b6&cKey=3bc280f8-7c03-49a3-a0c9-83da620cfb4d

    E-Print Network [OSTI]

    Shenoy, Krishna V.

    .abstractsonline.com/Plan/AbstractPrintView.aspx?mID=3527&sK...-50d3-406e-9abe-741db9e992b6&cKey=3bc280f8-7c03-49a3-a0c9-83da620cfb4d Print this Page.abstractsonline.com/Plan/AbstractPrintView.aspx?mID=3527&sK...-50d3-406e-9abe-741db9e992b6&cKey=3bc280f8-7c03-49a3-a0c9-83da620cfb4d tested

  4. Night Wind -Deliverable D.3.2 Main Simulation Report

    E-Print Network [OSTI]

    stores and background to the simulations 9 3 Cold store model and verification 11 3.1 The basic cold store model 11 3.2 Model verification 12 3.3 Assumptions 14 4 Cold store controllers and the NWCS 15 4 of cold stores) within a power system where there is a high degree of wind power penetration. The Night

  5. 1d, 2d, & 3d Simulations of Hurricane Wake

    E-Print Network [OSTI]

    Fox-Kemper, Baylor

    vs. unforced model #12;The Scaling of MLIs Mixed Layer Eddies (MLEs) begin as ageostrophic baroclinic MLEs form from MLIs, but scale differently due to an inverse cascade. See Fox-Kemper et al 08 #12;MLEs form from MLIs, but scale differently due to an inverse cascade. See Fox-Kemper et al 08 MLE

  6. Genome-wide transcriptional analyses of islet-specific CD4+ T cells identify Idd9 genes controlling diabetogenic T cell function

    E-Print Network [OSTI]

    Berry, Gregory J.; Frielle, Christine; Luu, Thaiphi; Salzberg, Anna C.; Rainbow, Daniel B.; Wicker, Linda S.; Waldner, Hanspeter

    2015-02-11

    Type 1 diabetes (T1D) is a polygenic disease with multiple insulin-dependent diabetes (Idd) loci predisposing humans and NOD mice to disease. NOD.B10 Idd9 congenic mice, in which the NOD Idd9 chromosomal region is replaced by the Idd9 from T1D...

  7. IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients

    E-Print Network [OSTI]

    Ferreira, Ricardo C.; Simons, Henry Z.; Thompson, Whitney S.; Cutler, Antony J.; Dopico, Xaquin Castro; Smyth, Deborah J.; Mashar, Meghavi; Schuilenburg, Helen; Walker, Neil M.; Dunger, David B.; Wallace, Chris; Todd, John A.; Wicker, Linda S.; Pekalski, Marcin L.

    2015-02-06

    thawing, PBMCs were resuspended in RPMI medi- um (Gibco, Paisley, UK) supplemented with 10% (vol/vol) FBS, 2 mol/l L-Glutamine and 100 ?g/ml Pen-Strep and cul- tured (106 PBMCs/well) in 24-well flat-bottom cell culture plates (BD Biosciences, San Diego, CA...

  8. CD4 count at presentation for HIV care in the United States and Canada: Are those over 50 years more likely to have a delayed presentation?

    E-Print Network [OSTI]

    2010-01-01

    JP, Mocroft A, Chiesi A, Kirk O, Roge B, Panos G, et al:Jacobson 1 , Gregory D Kirk 1 , Ann C Collier 9 , ConstanceBosch, Martin, Jacobson, Kirk, Napravnik, Goedert, Buchacz,

  9. Title: First year lymphocyte T CD4+ response to antiretroviral therapy according to the HIV type in the IeDEA West Africa collaboration.

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    (c) Service de Maladies Infectieuses et Tropicales (SMIT), Centre Hospitalier Universitaire (CHU) de, Mali (e) Centre de Prise en Charge des personnes vivant avec le VIH (PVVIH) du Centre Hospitalier]. Using this international database, we describe the case management of HIV-2 infected or dually positive

  10. Economic potential of a point-of-care CD4+ T cell count diagnostic in Mexico : a case study for low-end disruption diagnostics in middle of the pyramid Latin America

    E-Print Network [OSTI]

    Camargo Támara, Mauricio

    2012-01-01

    Disruptive models of innovation are starting to appear in healthcare. In the US, for instance, retail medicine clinics are changing the way in which patients satisfy their basic medical needs. In Mexico, similar retail ...

  11. Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1

    E-Print Network [OSTI]

    Mooij, Petra; Koopman, Gerrit; Drijfhout, Jan Wouter; Nieuwenhuis, Ivonne G.; Beenhakker, Niels; Koestler, Josef; Bogers, Willy M. J. M.; Wagner, Ralf; Esteban, Mariano; Pantaleo, Giuseppe; Heeney, Jonathan L.; Jacobs, Bertram L.; Melief, Cornelis J. M.

    2015-02-09

    ? de ? Biotecnologia, ? CSIC, ? Madrid, ? Spain; ?15 e Division ? of ? Immunology ? and ? Allergy, ? Centre ? Hospitalier ? Universitaire ? Vaudois, ?16 Lausanne, ? Switzerland; ? f Swiss ? Vaccine ? Research ? Institute, ? Lausanne, ? Switzerland...

  12. A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state

    E-Print Network [OSTI]

    2010-01-01

    PE conjugated CD1d tetramer loaded with PBS-57 (Alpha-was prepared by the NIH Tetramer Facility. A total of 1–2 ×CD3 lo , PBS57-loaded CD1d Tetramer+) in the liver of B6 (n=

  13. CSc-165 Spring 2015 Week 2 (d) 3D / Objects / Cameras

    E-Print Network [OSTI]

    Gordon, Scott

    Teapot(Color.blue); Matrix3D teaM = teap.getLocalTranslation(); teaM.translate(-1,1,-5); teap.setLocalTranslation(tea, xEnd, Color.red, 2); Line yAxis = new Line (origin, yEnd, Color.green, 2); Line zAxis = new Line

  14. Virus-enabled synthesis and 2D/3D assembly of nanowire networks

    E-Print Network [OSTI]

    Liau, Forrest (Forrest W.)

    2013-01-01

    Dense networks of high aspect ratio nanowires can provide important functionality to electronic devices through a unique combination of electronic and structural properties including high conductivity, high surface area, ...

  15. ATL INST, OF STAND & TECH R.I.C-A111D3 SED71b

    E-Print Network [OSTI]

    and Technology Telecommunications Security Guidelines for Telecommunications Management Network John Kimmins in the development of technology . . . needed to improve product quality, to modernize manufacturing processes Services · Manufacturing Extension Partnership · Standards Services · Technology Commercialization

  16. Proceedings of ALGORITMY 2009 A 2D/3D FINITE VOLUME METHOD USED TO SOLVE THE

    E-Print Network [OSTI]

    Coudière, Yves

    , that generate a non-stationary electrical field. The measures of this electrical field at the body surface to the evo- lution of the extracardiac electrical field. The coupling occurs through flux continuity experiments. 2. Principles of the computation of ECGs. 2.1. The bidomain equations. The computational domain

  17. A 3D-3C Reflection Seismic Survey and Data Integration to Identify...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Summary: Understanding geothermal reservoirs requires multi-discipline, integrated 3D GIS: Access down hole geophysical logs, surface geophysics, isotherms, isoresistivity...

  18. ?-deformation of B-twisted gauge theories and the 3d-3d correspondence

    E-Print Network [OSTI]

    Yuan Luo; Meng-Chwan Tan; Junya Yagi; Qin Zhao

    2015-02-07

    We study \\Omega-deformation of B-twisted gauge theories in two dimensions. As an application, we construct an \\Omega-deformed, topologically twisted five-dimensional maximally supersymmetric Yang-Mills theory on the product of a Riemann surface $\\Sigma$ and a three-manifold $M$, and show that when $\\Sigma$ is a disk, this theory is equivalent to analytically continued Chern-Simons theory on $M$. Based on these results, we establish a correspondence between three-dimensional $\\mathcal{N} = 2$ superconformal theories and analytically continued Chern-Simons theory. Furthermore, we argue that there is a mirror symmetry between {\\Omega}-deformed two-dimensional theories.

  19. Statistical methods for 2D-3D registration of optical and LIDAR images

    E-Print Network [OSTI]

    Mastin, Dana Andrew

    2009-01-01

    Fusion of 3D laser radar (LIDAR) imagery and aerial optical imagery is an efficient method for constructing 3D virtual reality models. One difficult aspect of creating such models is registering the optical image with the ...

  20. Visual geo-localization of non-photographic depictions via 2D-3D alignment

    E-Print Network [OSTI]

    and Josef Sivic Fig. 1 Our system automatically geo-localizes paintings, drawings, and historical, paintings and historical pho- tographs. This is achieved by aligning the input depiction with a 3D model of several scenes are represented by a set of discrim- inative visual elements that are automatically learnt

  1. Enhanced Pairing of Quantum Critical Metals Near d=3+1

    E-Print Network [OSTI]

    A. Liam Fitzpatrick; Shamit Kachru; Jared Kaplan; S. Raghu; Gonzalo Torroba; Huajia Wang

    2015-03-10

    We study the dynamics of a quantum critical boson coupled to a Fermi surface in intermediate energy regimes where the Landau damping of the boson can be parametrically controlled, either via large Fermi velocity or by large N techniques. We focus on developing a systematic approach to studying the BCS instability, including careful treatment of the enhanced log^2 and log^3 singularities which appear already at 1-loop. We also treat possible instabilities to charge density wave (CDW) formation, and compare the scales Lambda_{BCS} and Lambda_{CDW} of the onset of the instabilities in different parametric regimes. We address the question of whether the dressing of the fermions into a non-Fermi liquid via interactions with the order parameter field can happen at energies > Lambda_{BCS}, Lambda_{CDW}.

  2. 57th International Astronautical Congress 2006 IAC-06-D3.3.1

    E-Print Network [OSTI]

    de Weck, Olivier L.

    . Terrestrial logistics and supply chain management is a highly-developed field; techniques for efficient supply logistics. This paper describes the space logistics model developed by personnel at Massachusetts Institute FOR SUSTAINABLE SPACE EXPLORATION Mrs. Sarah A. Shull Massachusetts Institute of Technology (MIT), Cambridge, MA

  3. REGRESSION LEARNING FOR 2D/3D IMAGE REGISTRATION Chen-Rui Chou

    E-Print Network [OSTI]

    North Carolina at Chapel Hill, University of

    Frederick and Gig Mageras, for their extremely insightful suggestions on this research. I would like

  4. De-regulation of D-3-phosphoglycerate dehydrogenase by domain Jessica K. Bell1

    E-Print Network [OSTI]

    Grant, Gregory

    , Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA; 2 Department of Chemistry, University of Richmond, Richmond, Virginia, USA; 3 Department of Molecular Biology and Pharmacology

  5. DOI: 10.1002/cphc.200600390 Identification of the D3h Isomer of Carbon

    E-Print Network [OSTI]

    Kaiser, Ralf I.

    -bearing molecules such as ozone or carbon dioxide, ionizing radiation from the solar wind can liberate oxygen atoms enrichment of stratospheric carbon dioxide.[1­4] In view of radiation-induced degradation of oxygen.[17] However, despite the importance of the carbon trioxide isomers in atmospheric chemistry, to date

  6. C:\DOCUME~1\d3k776\LOCALS~1\TEM

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 OutreachProductswsicloudwsiclouddenDVA N C E D B L OBransenBusiness networking and59:80 (6pp), 201232

  7. A 3D-3C Reflection Seismic Survey and Data Integration to Identify the

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EAand Dalton JumpProgram | Open EnergyEnergyEnergyEnergySeismic Response of

  8. Enhanced pairing of quantum critical metals near d = 3 + 1 (Journal

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfate Reducing(Journal Article) | SciTech(Journal(Patent) |(Journal Article) | SciTechCarbon

  9. A 3D-3C Reflection Seismic Survey and Data Integration to Identify the

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustmentsShirleyEnergyTher i n c i p a l De p u t y A s s iof1 of 8 2Seismic Response of Fractures and

  10. Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B cell receptor signaling

    E-Print Network [OSTI]

    Tribolet, Leon; Cantacessi, Cinzia; Pickering, Darren; Navarro, Severine; Doolan, Denise; Trieu, Angela; Fei, Huang; Chao, Yang; Hofmann, Andreas; Gasser, Robin; Giacomin, Paul; Loukas, Alex

    2014-08-19

    , Sigma). 154 155 Flow cytometry and cell sorting 156 Cells were stained with fluorophore-conjugated antibodies against CD19 (HIB19), CD20 (2H7), 157 CD3 (OKT3), CD4 (OKT4), CD14 (61D3) CD69 (FN50), HLA-DR (LN3), CD80 (2D10.4), CD86 158 (IT2.2) (all... . Controlling the false discovery rate in 462 behavior genetics research. Behav Brain Res 2001; 125:279-84. 463 30. Boyle EI, Weng S, Gollub J, et al. GO::TermFinder--open source software for accessing Gene 464 Ontology information and finding significantly...

  11. arXiv:cond-mat/0504741v128Apr2005 d = 3 Anisotropic and d = 2 tJ Models

    E-Print Network [OSTI]

    Gozuacik, Devrim

    to the superconducting phase in high-Tc materials, persists even for strong anisotropy. While the phase appears at low of the superconducting phase in high-Tc materials.[4, 5] In fact, the calculated superfluid weight shows a marked peak regime, which is the one directly relevant to high-temperature superconductivity. The extension

  12. TRAC code assessment using data from SCTF Core-III, a large-scale 2D/3D facility

    SciTech Connect (OSTI)

    Boyack, B.E.; Shire, P.R.; Harmony, S.C.; Rhee, G.

    1988-01-01

    Nine tests from the SCTF Core-III configuration have been analyzed using TRAC-PF1/MOD1. The objectives of these assessment activities were to obtain a better understanding of the phenomena occurring during the refill and reflood phases of a large-break loss-of-coolant accident, to determine the accuracy to which key parameters are calculated, and to identify deficiencies in key code correlations and models that provide closure for the differential equations defining thermal-hydraulic phenomena in pressurized water reactors. Overall, the agreement between calculated and measured values of peak cladding temperature is reasonable. In addition, TRAC adequately predicts many of the trends observed in both the integral effect and separate effect tests conducted in SCTF Core-III. The importance of assessment activities that consider potential contributors to discrepancies between the measured and calculated results arising from three sources are described as those related to (1) knowledge about the facility configuration and operation, (2) facility modeling for code input, and (3) deficiencies in code correlations and models. An example is provided. 8 refs., 7 figs., 2 tabs.

  13. PHYSICAL REVIEW A 83, 042511 (2011) Experimental and theoretical study of the 6d3/2 polarizability of cesium

    E-Print Network [OSTI]

    Safronova, Marianna

    2011-01-01

    of cesium A. Kortyna, C. Tinsman, and J. Grab* Department of Physics, Lafayette College, Easton (Received 8 February 2011; published 20 April 2011) We report polarizability measurements of atomic cesium accurate atomic-physics PNC measurement has been carried out in atomic cesium [4]. Interpreting

  14. The massive fermion phase for the U(N) Chern-Simons gauge theory in D=3 at large N

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Bardeen, William A.

    2014-10-07

    We explore the phase structure of fermions in the U(N) Chern-Simons Gauge theory in three dimensions using the large N limit where N is the number of colors and the fermions are taken to be in the fundamental representation of the U(N) gauge group. In the large N limit, the theory retains its classical conformal behavior and considerable attention has been paid to possible AdS/CFT dualities of the theory in the conformal phase. In this paper we present a solution for the massive phase of the fermion theory that is exact to the leading order of ‘t Hooft’s large Nmore »expansion. We present evidence for the spontaneous breaking of the exact scale symmetry and analyze the properties of the dilaton that appears as the Goldstone boson of scale symmetry breaking.« less

  15. The type Ia supernova SNLS-03D3bb from a super-Chandrasekhar-mass white dwarf star

    E-Print Network [OSTI]

    2008-01-01

    magnitudes of Type IA supernovae. Astrophys. J. Lett. 413,from 42 High-Redshift Supernovae. Astrophys. J. 517, 565–Observational Evidence from Supernovae for an Accelerating

  16. The massive fermion phase for the U(N) Chern-Simons gauge theory in D=3 at large N

    SciTech Connect (OSTI)

    Bardeen, William A.

    2014-10-07

    We explore the phase structure of fermions in the U(N) Chern-Simons Gauge theory in three dimensions using the large N limit where N is the number of colors and the fermions are taken to be in the fundamental representation of the U(N) gauge group. In the large N limit, the theory retains its classical conformal behavior and considerable attention has been paid to possible AdS/CFT dualities of the theory in the conformal phase. In this paper we present a solution for the massive phase of the fermion theory that is exact to the leading order of ‘t Hooft’s large N expansion. We present evidence for the spontaneous breaking of the exact scale symmetry and analyze the properties of the dilaton that appears as the Goldstone boson of scale symmetry breaking.

  17. Magnetic order and electronic structure of 5d3 double perovskite Sr2ScOsO6

    SciTech Connect (OSTI)

    Calder, Stuart A; Morrow, Ryan; Taylor, Alice E; Lumsden, Mark D; Woodward, Patrick; Christianson, Andrew D; Singh, David J

    2015-01-01

    The magnetic susceptibility, crystal and magnetic structures, and electronic structure of double perovskite Sr2ScOsO6 are reported. Using both neutron and x-ray powder diffraction we find that the crystal structure is monoclinic P21/n from 3.5 to 300 K. Magnetization measurements indicate an antiferromagnetic transition at TN=92 K, one of the highest transition temperatures of any double perovskite hosting only one magnetic ion. Type I antiferromagnetic order is determined by neutron powder diffraction, with an Os moment of only 1.6(1) muB, close to half the spin-only value for a crystal field split 5d electron state with t2g^3 ground state. Density functional calculations show that this reduction is largely the result of strong Os-O hybridization, with spin-orbit coupling responsible for only a ~0.1 muB reduction in the moment.

  18. supplemental_lists_1d-2d-3c_06-24-2011.xls | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LIST OFAMERICA'S FUTURE.EnergyWooden RooftopsNRC FORM 74116,

  19. Regular unipotent elements Elements unipotents reguliers

    E-Print Network [OSTI]

    Bonnafé, Cédric

    GF . Alors il existe un ´el´ement unipotent r´egulier v dans LF tel que RG LPG u = L v o`u G u est un ´el´ement unipotent r´egulier de GF et soit uL = resG L u. Alors RG LPG u = L uL . L

  20. Immunity to Toxoplasma gondii

    E-Print Network [OSTI]

    Grover, Harshita Satija

    2012-01-01

    T. gondii +AS15 Naive Tetramer IFN-? B. CD4 CD4 Immunized +IFN-? or by staining with tetramers. A) Representative flowAPC: IFN-? Spleen Spleen Tetramer C. E. Brain Brain Figure

  1. Data:94d06976-03c6-46f7-a433-abc5f4968d3a | Open Energy Information

    Open Energy Info (EERE)

    under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic Information 2. Demand 3. Energy << Previous 1 2 3 Next >> Basic Information...

  2. Expression of vitamin D target genes and proteins in human osteosarcoma cell line, 143B, in response to 1-alpha,25-dihydroxyvitamin D3

    E-Print Network [OSTI]

    Wang, Shanshan

    2010-06-08

    of the study was to find out the relationship between calcitriol treatment and expression levels of vitamin D target genes: vitamin D receptor (VDR), 1?-hydroxylase (CYP27B1), 24 hydroxylase (CYP24A1), runt related transcription factor-2 (RUNX-2...

  3. The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)(2)-vitamin D-3 in vivo and in vitro

    E-Print Network [OSTI]

    Huhtakangas, J A; Olivera, C J; Bishop, J E; Zanello, L P; Norman, Anthony W

    2004-01-01

    induces translocation of the vitamin D receptor (VDR) to therelationships in the vitamin D endocrine system. Endocr Revterminal variant human vitamin D receptor gene transcripts.

  4. Vitamin D3 effects on lipids differ in statin and non-statin-treated humans: Superiority of free 25-OH D levels in detecting relationships

    E-Print Network [OSTI]

    2013-01-01

    827-828. Autier P, Gandini S: Vitamin D supplementation and1737. Michos E, Blumenthal R: Vitamin D supplementation andD: New insights about vitamin D and cardiovascular disease.

  5. Session II-D-3 American Society for Engineering Education March 27, 2004 Bradley University/Illinois Central College, Peoria, Illinois

    E-Print Network [OSTI]

    Kostic, Milivoje M.

    % Otto (gasoline) engine 25-35 Diesel engine 30-40 Gas turbine 30-40 Steam turbine 30-40 Nuclear, steam turbine 30-35 Combined gas/steam turbines 40-55+ Fuel cell (hydrogen, etc.) 40-60+ Photovoltaic cell 10-20 Windmill 30-40 (59% limit) Hydro turbine 80-85 Electro-mechanical motor/generator 80-95 NOTE: Thermal

  6. Efficacy of high-concentration tacalcitol ointment in psoriasis vulgaris after changing from other high-concentration vitamin D3 ointments

    E-Print Network [OSTI]

    Abe, Masatoshi; Syuto, Tomoko; Ishibuchi, Hirohisa; Sogabe, Yoko; Yokoyama, Yoko; Ishikawa, Osamu

    2008-01-01

    with chronic plaque psoriasis. Br J Dermatol. 2002 Mar;146(in the management of psoriasis. Am J Clin Dermatol. 2001 ;2(of chronic plaque psoriasis in dermatological practice.

  7. 734 IEEE TRANSACTIONS ON SUSTAINABLE ENERGY, VOL. 4, NO. 3, JULY 2013 Hybrid 2D-3D Space Vector Modulation Voltage

    E-Print Network [OSTI]

    Fu, Yong

    , such as ac drives, uninterruptible power supplies (UPS), switching compensators, and unified power flow, flexibility, and the performance of the network [1]. Power elec- tronic converters constitute the controllable an islanded operation. Three-phase inverters are employed in power systems and industrial applications

  8. Open D3t8, E-ReseaFch, I N F O R M AT I O N and communication

    E-Print Network [OSTI]

    open access institu- tional repositories and Web 2.0 technologies. Recent research carried out experimentation or "dark data" ("F'Yeeing tbe Dark Data of Failed Scientific Experiments," hy Tbomas Goetz, Wired

  9. Section IV.D.3 for DOE 2013 Annual Report: Novel Phosphazene-based Compounds to Enhance Safety and Stability of Cell Chemistries for High Voltage Applications (INL)

    SciTech Connect (OSTI)

    Kevin L. Gering; Mason K. Harrup; Eric J. Dufek; Sergiy V. Sazhin; Harry W. Rollins; David K. Jamison; Fred F. Stewart; John Burba

    2013-09-01

    Electrolytes play a central role in performance and aging in most electrochemical systems. As automotive and grid applications place a higher reliance on electrochemical stored energy, it becomes more urgent to have electrolyte components that enable optimal battery performance while promoting battery safety and longevity. Safety remains a foremost concern for widespread utilization of Li-ion technology in electric-drive vehicles, especially as the focus turns to higher voltage systems (5V). This work capitalizes on the long established INL expertise regarding phosphazene chemistry, aimed at battery-viable compounds for electrolytes and electrodes that are highly tolerant to abusive conditions. This report showcases our 2013 work for the DOE applied battery research (ABR) program, wherein testing results are summarized for INL electrolytes and alternative anode materials.

  10. Non-perturbative quantum effects in stringy degenerate geometries: Vacuum created pair of $(D{\\bar D})_3$-brane by a two form

    E-Print Network [OSTI]

    K. Priyabrat Pandey; Abhishek K. Singh; Sunita Singh; Supriya Kar

    2015-04-26

    We obtain axionic charged primordial black holes on a vacuum created gravitational pair of $(3{\\bar 3})$-brane by the Kalb-Ramond field on a $D_4$-brane in presence of a background open string metric. The new geometries on an emergent pair of $(3{\\bar 3})$-brane universe is shown to be influenced by the non-perturbative quantum effects underlying a geometric torsion in a second order formalism. The presence of small extra dimensions transverse to the pair in the formalism ensures dynamical scalar fields hidden to a $3$-brane or an anti 3-brane universe. We investigate the non-perturbative quantum vacua for their characteristic properties to explain the accelerated expansion of our universe. Interestingly the emergent brane universe is shown to possess its origin in a degenerate stringy de Sitter vacua at an early epoch. A non-perturbative $D_p$-brane world volume correction for $p < 3$ is worked out to explain some of the quantum effects underlying a quintessence axion in the string-brane setup. Our analysis reveals that a $D$-instanton can be a potential candidate to source the dark energy in our brane universe.

  11. A novel particle time of flight diagnostic for measurements of shock-and compression-bang times in D3He and DT implosions at the NIF

    E-Print Network [OSTI]

    ) A dual-channel, focusing x-ray spectrograph with uniform dispersion for Z pinch plasmas measurement Rev. Olson,4 J. Kline,5 and J. Kilkenny6 1 Massachusetts Institute of Technology, Cambridge, Massachusetts

  12. Summary - WTP Pretreatment Facility

    Office of Environmental Management (EM)

    prio To view the full T http:www.em.doe. objective of a Tech ements (CTEs), usin HanfordORP Waste Treatme March 2007 Departmen te Treatm E-EM Did This um Nitric Acid R a...

  13. Exploring the Neutrinoless Double Beta Decay in the Inverted Neutrino Hierarchy with Bolometric Detectors

    E-Print Network [OSTI]

    Artusa, D. R.

    2014-01-01

    Exploring the Neutrinoless Double Beta Decay in the InvertedC. Giunti, Neutrinoless double-beta decay. A brief review,el- ements for neutrinoless double-beta decay and double-

  14. Energy Efficient Nanoelectronic System Design

    E-Print Network [OSTI]

    Mohanty, Saraju P.

    Example Electronic System: Secure Digital Camera Power Manag ement Unit (PMU) 05/21/2013 17 #12;Power Management Unit (PMU) Manages the power distribution to the various subsyst

  15. Centrale nucleaire de production d'electricite. Analyse d'une centrale type P.W.R. du palier 900 MWe.

    E-Print Network [OSTI]

    Ravelet, Florent

    / tonne), il reste : ´el´ements potentiellement fissiles ; beaucoup d'Uranium 238 ; produits de fission) et aspersion. Contr^ole du niveau. Une / boucle (branche froide). H´elico-centrifuge mono-´etage. Qv

  16. Milk fat composition of a lactating dairy cow as influenced by abomasal infusion of various long chain fatty acids 

    E-Print Network [OSTI]

    Switzer, Leonard Anderson

    1971-01-01

    Ql 0 tD E IQ CD 4 ID 3 0 0 0 4 Q? 0 ttl CQ 0 0 4 4 LQ 0 Ln CJ 4 tD 3 0 Q- Q? IQ cnl 4 tD 3 Ql 0 CI 0 0 Q- 4 L- ID 0 Gl Lnl o cn 0 4 CQ 3 tD 0 0 0 C Q- 4 Q- IQ 0 Ql cnl cl cn ID 37 IQ V tl In U 4 O cnl 0 CO F ll O... in the same column uith dif'ferent superscripts (a, b, c) differed significantly (P&0. 05). 20 03 C 'I Cll IO LO I CO M OI IO N M IO N IO H C7I 4 LC3 D N M C LO CO D rt W N t N D Ot Cll N N CO LO IO (O CO D D D N \\0 IO LO (8 N N N LO M D f71 CII...

  17. Strengthening Line Management Oversight and Federal Monitoring...

    Office of Environmental Management (EM)

    1 Nuclear Safety Basis Program Review Overview and Management Oversight Facility Life Cycle Applicability CD-1 CD-2 CD-3 CD-4 Operations and Transitions Decommissioning &...

  18. Soil and Groundwater Cleanup - In-Situ Grouting, Lessons Learned...

    Energy Savers [EERE]

    Soil and Groundwater Cleanup - In-Situ Grouting, Lessons Learned (Post CD-4), Environmental Management Cleanup, May 2011 Soil and Groundwater Cleanup - In-Situ Grouting, Lessons...

  19. Lot #62W (Red Cedar Road).........................................................................................................................D3 Rate is 80 per half hour for visitors. The rate is 40 per half hour for alumni with valid MSU Alumni

    E-Print Network [OSTI]

    )................................................................................................................................... B5 Employee parking and 147 metered spots. Meter rate is $1.50 per hour. Ramp #2 (Auditorium Road. Employee parking spaces are available to visitors 6pm through 7am Monday-- Friday and all day weekends Library) is available to visitors 11pm through 7am Monday--Friday and after 2pm Saturday and Sunday. ( 2

  20. Observations of Comets C/2007 D1 (LINEAR), C/2007 D3 (LINEAR), C/2010 G3 (WISE), C/2010 S1 (LINEAR), and C/2012 K6 (McNaught) at large heliocentric distances

    E-Print Network [OSTI]

    Ivanova, Oleksandra; Krišandova, Zuzana Seman; Svore?, Jan; Korsun, Pavlo; Afanasiev, Viktor; Resetnyk, Volodymyr; Andreev, Maxim

    2015-01-01

    Photometric and spectroscopic observations of five nearly parabolic comets with eccentricity larger than 0.99 at heliocentric distances greater than 4 AU were performed. No molecular emission was observed for any studied comet and the entire cometary activity in all cases was attributed to dust production. Upper limits of the gas production rates for the main neutral molecules in the cometary comae were calculated. The derived values of dust apparent magnitudes were used to estimate the upper limit of the geometric cross-section of cometary nuclei (upper limits of radii range from 2 km to 28 km). Due to the poor sublimation of water ice at these distances from the Sun, other mechanisms triggering activity in comets are discussed.

  1. Extensive investigation of reticuloendotheliosis virus in the endangered Attwater's prairie chicken 

    E-Print Network [OSTI]

    Bohls, Ryan Lanier

    2007-09-17

    ........................................................................................... 82 V FLOW CYTOMETRIC ANALYSIS OF REV INFECTION IN CD4 + AND CD8 + T CELLS...................................................................................... 84 Introduction... ................................................................................................ 81 15. Comparison of CD4 + and CD8 + T cell percentages in REV infected and uninfected Attwater’s prairie chickens.................................................................... 90 ix 16. Histograms showing percentage of cells...

  2. Wind Power and the Clean Development Mechanism

    E-Print Network [OSTI]

    . data source: www.CD4CDM.org compiled by J. Fenhann UNEP Risoe Centre CDM Pipeline of Projects (UNFCCC, Philippines EC-ASEAN ENERGY FACILITY #12;CD4CDM project Objective · Help developing countries participate : Cambodia, Philippines, Vietnam · Latin America: Bolivia, Ecuador, Guatemala · Middle East and North Africa

  3. Flow visualization of molten alloys using real-time neutron radiography 

    E-Print Network [OSTI]

    Bennett, Tami Norene

    1994-01-01

    . To observe the flow of molten metals induced by natural convection, an experiment was attempted using the lead-bismuth (Pb-Bi) eutectic with tracer particles made of the intermetallic compound gold-cadmium (AuCd4). The Pb-Bi material, with the AuCd4 particles...

  4. Faculte de Sciences Appliquees Service Ingenierie Informatique

    E-Print Network [OSTI]

    Libre de Bruxelles, Université

    de monitoring conforme ITIL : Application au r´eseau A.S.T.R.I.D. Nicolas Vannieuwerburgh Directeur se base sur une impl´ementation d'ITIL qui devra satisfaire la solution de surveillance du syst`eme. Ce m´emoire contiendra donc une intro- duction `a ITIL via ses diff´erents ouvrages, ainsi qu

  5. A Metaphor Graphics Based Representation of Digital Libraries on the World Wide Web: Using the libViewer to Make Metadata Visible

    E-Print Network [OSTI]

    Rauber,Andreas

    A Metaphor Graphics Based Representation of Digital Libraries on the World Wide Web: Using the lib way to go. Most interfaces to digital libraries present themselves as various forms of sorted lists interface to digital libraries using metaphor graphics to display information on the el­ ements in a digital

  6. A Metaphor Graphics Based Representation of Digital Libraries on the World Wide Web: Using the libViewer to Make Metadata Visible

    E-Print Network [OSTI]

    Rauber,Andreas

    A Metaphor Graphics Based Representation of Digital Libraries on the World Wide Web: Using the lib way to go. Most interfaces to digital libraries present themselves as various forms of sorted lists interface to digital libraries using metaphor graphics to display information on the el- ements in a digital

  7. RENEWAL THEORY IN ANALYSIS OF TRIES AND SVANTE JANSON

    E-Print Network [OSTI]

    Janson, Svante

    ´ement, Flajolet and Vall´ee [7] for various interesting probability models of random strings. Renewal theory of the purposes of this paper is to make propaganda for the use of renewal theory to study e.g. Markov modelsRENEWAL THEORY IN ANALYSIS OF TRIES AND STRINGS SVANTE JANSON To my colleague and friend Allan Gut

  8. Finite Element Approximation of the Acoustic Wave Equation: Error Control and Mesh

    E-Print Network [OSTI]

    Bangerth, Wolfgang

    Finite Element Approximation of the Acoustic Wave Equation: Error Control and Mesh Adaptation of the Acoustic Wave Equation: Error Control and Mesh Adaptation Wolfgang Bangerth and Rolf Rannacher1 Institute@iwr.uni-heidelberg.de Abstract We present an approach to solving the acoustic wave equation by adaptive finite el- ement methods

  9. ON CONVECTIVE HEAT TRANSFER IN BUILDING ENERGY ANALYSIS

    E-Print Network [OSTI]

    Gadgil, Ashok Jagannath

    2013-01-01

    an ement of fluid in a steady laminar flow, can be used tolaminar, the f1uid flows along streamli defined by *For steady flow~ fluid particles flowlaminar boundary layer thickness, L v'Re RECIRCULATING FLOW INDUCED IN A FLUID

  10. UNIVERSITE PAUL VERLAINE, METZ Annee Universitaire 2007/2008 Departement de Mathematiques

    E-Print Network [OSTI]

    Mortini, Raymond

    |) anz converge localement uniform´ement sur C produit f(z) = n=0 sin(anz) anz converge pour tout z C , que f est la trace d'une fonction enti`ere et que pour tout z C |f(z)| exp( n=0 an|z|). #12;UNIVERSITE PAUL VERLAINE, METZ Ann´ee Universitaire

  11. 1014 IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, VOL. 52, NO. 3, MARCH 2004 Recycling Ambient Microwave Energy With

    E-Print Network [OSTI]

    are in wireless powering of industrial sensors and recycling of ambient RF energy. A 64-el- ement dual Ambient Microwave Energy With Broad-Band Rectenna Arrays Joseph A. Hagerty, Student Member, IEEE, Florian] including utility power satellites [5], mechanical actuators for space-based telescopes [6], small dc motor

  12. 746 IEEE TRANSACTIONS ON MAGNETICS, VOL. 36, NO. 4, JULY 2000 Solving 3D Eddy Current Problems Using Second

    E-Print Network [OSTI]

    Ida, Nathan

    746 IEEE TRANSACTIONS ON MAGNETICS, VOL. 36, NO. 4, JULY 2000 Solving 3D Eddy Current ProblemsD eddy current prob- lems. The asymmetry of the facet related functions in the edge el- ement basis- ments is compared through an example. Index Terms--Eddy currents, finite element modeling, second order

  13. Requirements-Based Design Guidance: A Process-Centered Consistency Management Approach

    E-Print Network [OSTI]

    Cass, Aaron G.

    on the relationships between requirements elements and design el- ements can be used to guide designers in making on the relationships between requirements elements and design elements can be used to guide design- ers in making diagrams (design elements), given use cases with activity diagrams (requirements elements). From

  14. RequirementsBased Design Guidance: A ProcessCentered Consistency Management Approach

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    on the relationships between requirements elements and design el­ ements can be used to guide designers in making on the relationships between requirements elements and design elements can be used to guide design­ ers in making diagrams (design elements), given use cases with activity diagrams (requirements elements). From

  15. Modelling of dune patterns by short range interactions Clement Narteau, Eric Lajeunesse, Francois Metivier & Olivier Rozier

    E-Print Network [OSTI]

    Narteau, Clément

    Modelling of dune patterns by short range interactions Cl´ement Narteau, Eric Lajeunesse, Franc on crescentic barchan dunes that are used as a benchmark for our numerical model of bedforms. Length and time scales of isolated barchan dunes are studied in order to constrain the parameters of the model. Then we

  16. Morphology and Anatomy of Texas Persimmon (Diospyros texana Scheele). 

    E-Print Network [OSTI]

    Meyer, R. E.

    1974-01-01

    in Figure 3C ancl wit11 part of the corolla and calyx reinoved in Figure 3D. , Fifteen male stems with four e1011g;ition-growth increments each were collected from plants at George- town on April I, 197 1. Krancll inci-ements, beginning ;it...

  17. Bonneville Power Administration's Purchasing of Energy Savings 

    E-Print Network [OSTI]

    Schick, H.

    1985-01-01

    features include the type of financing to be used (shared savings, leasing, interna1 fi nanc ing, etc.), documentat i on ,of the financial stability of the sponsor and the,parti ci pants, the terms of the contractua1 agr~ement, and the incentive level...

  18. Biogeosciences, 4, 905911, 2007 www.biogeosciences.net/4/905/2007/

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , with carbon sequestration rates being highly sen- sitive even to minor climatic fluctuations (Yu et al., 2003 played a critical role in the cycling of elements coupled to carbon dynamics. Dry phases caused increased in carbon release, which leads to an enrichment of el- ements, may enhance the export of stored contaminants

  19. Mod`ele Elements Finis d'un Pli Vocal Artificiel avec Couplage Hydro-elastique

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Mod`ele El´ements Finis d'un Pli Vocal Artificiel avec Couplage Hydro-´elastique N. Hermanta , F formulation variationnelle du couplage hydro-élastique. Un premier calcul hyper-élastique simule le gonflement dans l'analyse modale des vibrations de petite amplitude du système hydro-élastique, permettant ainsi

  20. An efficient Java implementation of the immediate successors calculation

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    An efficient Java implementation of the immediate successors calculation Cl´ement Gu´erin, Karell an effective Java imple- mentation of the concept immediate successors calculation. It is based on the lattice Java library, developed by K. Bertet and the Limited Objects Access algorithm, proposed by C. Demko [5

  1. ,,INTERNET-KLINIK" Neue Medien in der Psychotherapie

    E-Print Network [OSTI]

    Manstein, Dietmar J.

    ,,INTERNET-KLINIK" Neue Medien in der Psychotherapie Martina de Zwaan Klinik für Psychosomatik und Psychotherapie #12;Internet = Alltagsmedium 78% der Erwachsenen in Deutschland verwenden das Internet Klinik für · E-Mental Health: Nutzung von Informations- und Kommunikationstechnologien (IKT; Computer, Internet

  2. Proceedings of PASCO 2010: Parallel Symbolic Computation 2010 Editors: Marc Moreno Maza and Jean-Louis Roch

    E-Print Network [OSTI]

    Moreno Maza, Marc

    multi-criteria objectives: time, energy consumption, resource usage, reliability. In this context on Symbolic and Algebraic Computation (ISSAC) in Munich, Germany. Immediately prior to the ISSAC 2010 meeting Char (USA) Winfried Neun (Germany) Gene Cooperman (USA) Cl´ement Pernet (France) Gabriel Dos Reis (USA

  3. Proceedings of the WORKSHOP on Fundamental Issues and Future Research Directions for Parallel Mechanisms and Manipulators

    E-Print Network [OSTI]

    Hayes, John

    , it is natural to call them constraint surfaces. Kinematic analysis of GP3LP reduces to intersection problems Mechanisms and Manipulators October 3­4, 2002, Quebec City, Quebec, Canada Cl´ement M. Gosselin and Imme Ebert-Uphoff, editors Architecture Independent Workspace Analysis of Planar Three-Legged Manipulators M

  4. Technische Universitat Berlin Fakultat II -Mathematik und Naturwissenschaften

    E-Print Network [OSTI]

    Mehl, Christian

    principal. Exercice 3 (L'anneau Z[i 5]). On consid`ere l'anneau A = Z[i 5] := {a + ib 5; a, b Z}. On d´efinit la norme d'un ´el´ement z = a + ib 5 par N(z) := z.¯z = a2 + 5b2 . (1) Montrer que la norme est

  5. Constraints: An International Journal, 3, 203--212 (1998) fl 1998 Kluwer Academic Publishers, Boston. Manufactured in The Netherlands.

    E-Print Network [OSTI]

    Leeds, University of

    1998-01-01

    'e Paris­Nord, Avenue J.­B. Cl'ement, F­93430 Villetaneuse, France AMAR ISLI isli@scs.leeds.ac.uk Division of Artificial Intelligence, School of Computer Studies, University of Leeds, Leeds LS2 9JT, United Kingdom representation) The network representation of P is the labelled directed graph of which the vertices

  6. AN HTML TUTORIAL Java applets are embedded in HTML files. HTML (HyperText Markup Language)

    E-Print Network [OSTI]

    Liang, Y. Daniel

    . The Web is the major reason for its popularity. HTML documents are displayed by a program called a Web browser. When a doc- ument is coded in HTML, a Web browser interprets the HTML to identify the el- ements-to-use authoring tools for creating Web pages. For example, you can create HTML files using Microsoft Word

  7. Journal of Electron Spectroscopy and Related Phenomena 155 (2007) 2834 Electron Compton scattering from methane and methane-d4

    E-Print Network [OSTI]

    Hitchcock, Adam P.

    2007-01-01

    from methane and methane-d4 G. Coopera, A.P. Hitchcocka,, C.A. Chatzidimitriou-Dreismannb, M. Vosc]. © 2006 Elsevier B.V. All rights reserved. Keywords: Quasi-elastic electron scattering; Methane; CD4

  8. Protein engineering for cancer therapy

    E-Print Network [OSTI]

    Liu, David Victor

    2012-01-01

    The immunosuppressive effects of CD4?CD25? regulatory T cells (Tregs) interfere with anti-tumor immune responses in cancer patients. In the first part of this work, we present a novel class of engineered Interleukin-2 ...

  9. Strengthening Line Management Oversight and Federal Monitoring...

    Office of Environmental Management (EM)

    Plan Volume 5 Nuclear Safety Basis Program Review of TSRs, USQs and SERs Facility Life Cycle Applicability CD-1 CD-2 CD-3 CD-4 Operations and Transitions Decommissioning &...

  10. Uptake and Presentation of Antigen by B Cells 

    E-Print Network [OSTI]

    Brooks, Katharine E

    B cells internalize antigen in a specific manner through the B cell receptor (BCR). The antigen is processed into peptides that are loaded on to MHC class II molecules and presented to CD4+ T cells. I have investigated ...

  11. T cell polarisation by dendritic cells: a role for Notch ligands? 

    E-Print Network [OSTI]

    Worsley, Alan GF

    2009-01-01

    The intention of the work described in this thesis was to identify whether the Notch signalling pathway is utilized by antigen presenting cells in order to influence CD4+ adaptive immune responses. The notion that Notch ...

  12. Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg. 

    E-Print Network [OSTI]

    Stephens LA; Malpass KH; Anderton SM

    2009-01-01

    The potential use of CD4(+)Foxp3(+) Treg as a cellular therapy for autoimmune disease is of great interest. For clinical translation, the key objective is to reverse established disease. Here we demonstrate that myelin ...

  13. Peptide immunotherapy in models of allergic airways disease 

    E-Print Network [OSTI]

    MacKenzie, Karen Joan

    2011-11-25

    Allergen-reactive CD4+ T cells are implicated in the pathogenesis of allergic disease. Peptide immunotherapy (PIT) involves therapeutic administration of short immunodominant peptides from within the protein allergen to ...

  14. Engineering of HIV gp120 by yeast surface display for neutralizing antibody characterization and immunogen design

    E-Print Network [OSTI]

    Mata-Fink, Jordi

    2013-01-01

    The sequence diversity of glycoprotein gp120 of the envelope spike of Human Immunodeficiency Virus (HIV) allows the virus to escape from antibody selection pressure. Certain conserved epitopes, like the CD4 binding site, ...

  15. FY 2014 Q3 RCA CAP Performance Metrics Report 2014-09-05.xlsx

    Energy Savers [EERE]

    no later than CD-3. ContractProject Management Performance Metrics FY12-FY14: 52 completions through 3rd Qtr. CD-4: Critical Decision-4, Approve Start of OperationsProject...

  16. On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells

    E-Print Network [OSTI]

    Song, Qing

    The frequencies of antigen-specific CD4+ T cells in samples of human tissue have been difficult to determine accurately ex vivo, particularly for autoimmune diseases such as multiple sclerosis or type 1 diabetes. Conventional ...

  17. Pilomatrical carcinoma: A case in a patient with HIV and hepatitis C

    E-Print Network [OSTI]

    Scheinfeld, Noah

    2008-01-01

    in a patient with HIV and hepatitis C Dermatology Onlinea 51-year-old man with HIV, hepatitis C, and pilomatricalCD4 count of 84, and hepatitis C with hepatic cirrhosis,

  18. N-3 Polyunsaturated Fatty Acids Reduce Th17 Differentiation by Decreasing Responsiveness to Interleukin-6 in Mice 

    E-Print Network [OSTI]

    Allen, Marilyn Jean

    2014-05-29

    CD4^(+) effector T cell subsets (e.g., Th1, Th17) are implicated in autoimmune and inflammatory disorders such as multiple sclerosis, psoriasis and rheumatoid arthritis. For optimal activation, IL-6 induces Th17 polarization and signals through...

  19. Modulation of purified murine T cell subset activation by dietary n-3 Polyunsaturated fatty acids 

    E-Print Network [OSTI]

    Arrington, Jennifer L

    2000-01-01

    n-3 Polyunsaturated fatty acids (PUFA) have been shown to reduce inflammation in diseases such as rheumatoid arthritis. The present studies sought to elucidate mechanisms whereby n-3 PUFAs downregulate T cell proliferation and affect CD4 and CD8...

  20. Effect of tolerogenic peptide administration on pathogenic antigen-experienced T cells 

    E-Print Network [OSTI]

    McPherson, Rhoanne Catherine

    2012-11-30

    The administration of soluble antigenic peptides is known to be effective at inducing tolerance in naïve antigen-reactive CD4+ T cells. This observation forms the basis of antigen-based therapy, which offers the potential ...

  1. Differential activation of bovine T lymphocyte subpopulations in response to mitogen and superantigen stimulation 

    E-Print Network [OSTI]

    Keahey, Jennifer Leigh

    2000-01-01

    This study examined the response of bovine CD4?, CD8?, and TCR ?[] T lymphocytes to activation with the mitogens concanavalin A (Con A), phytohemagglutinin (PHA), and pokeweed mitogen (PWM), and the superantigens Staphylococcus enterotoxin A (SEA...

  2. Developmental arrest of T cells in RpL22-deficient mice is dependent upon multiple p53 effectors

    E-Print Network [OSTI]

    Stadanlick, Jason E.

    alpha beta and gamma delta lineage T cells are thought to arise from a common CD4–CD8– progenitor in the thymus. However, the molecular pathways controlling fate selection and maturation of these two lineages remain poorly ...

  3. The effect of stratigraphy and soil plasticity on the settlement characteristics of reclaimed surface mined land 

    E-Print Network [OSTI]

    Rangel, Jorge Enrique

    1979-01-01

    of the manuscript I am grateful to my fellow graduate students who worked with me in this thesis: I thank Richard M. Pollard for his skillful operation of the Scanning Electron microscope whicn produced optimum microphotographs very important...THE EFFECT OF STRATIGRAPHY AND SOIL PLASTICITY ON THE SETTLEMENT CHARACTERISTICS OF FECLAIMED SURFACE MINED I~D A Thesis GORGE ENRIQUE RANGEL Submitted to the Graduate College of Texas ASM University in partial fulfillment of the regni ement...

  4. Convective rainfall estimation from digital GOES-1 infrared data 

    E-Print Network [OSTI]

    Sickler, Gary L

    1979-01-01

    scheme was adapted for this study and used with the digital geostationary satellite data. The concept of enhancement curves with respect to rainfall approxima- tion is discussed. Raingage rainfall analyses and satellite-derived rainfall estimation... digital geostationary infrared satellite data is feasible. A CKNOWLE DG EMENT S The author's graduate program was sponsored and financed by the Air Force Institute of Technology, United States Air Force. I would like to express my appreciation...

  5. Hydrothermal metamorphism and low-temperature alteration on the Mid-Atlantic ridge 

    E-Print Network [OSTI]

    Peron, Philippe Raymond

    1978-01-01

    and trace el- ement compositions and mineralogy of low-temperature altered basalts and hydrotherally alt. ered (metamorphosed) basalts; (2) to compare these an- alyses to those of experimentally altered basalts and to those of meta- morphosed oceanic... by changes of whole rock elemental compositions. Humphris (1975) finds TAB1. E 1: Minerals commonly found in metamorphic submarine basalts. Study Minerals Method of identification Miyashiro et al. (1971) chlorite, quartz, epidote albite, natrolite...

  6. Boundary element based multiresolution shape optimisation in electrostatics

    E-Print Network [OSTI]

    Bandara, Kosala; Cirak, Fehmi; Of, Günther; Steinbach, Olaf; Zapletal, Jan

    2015-05-18

    does not lead to non-physical oscillations in geometry. Moreover, the occurrence mesh pathologies, like inverted elements, is greatly reduced because the support size of the geometry modifications and e element sizes are well coordinated. This paper... of the cylinder contains 264 ements. The creases on the cylinder are not tagged. Therefore, the geometry becomes smoother while it is refined by bdivision. As a design constraint, the inner surface of the cylinder is required to have a constant radius for a bolt...

  7. The function of interpretation as perceived by park visitors and interpreters 

    E-Print Network [OSTI]

    Silvy, Valeen Adams

    1977-01-01

    . . . . . . . . . . . . 1 A comparison of perception stat. ement means and visitor/interpreter by reasons for attending programs. 79 81 CHAPTER I INTRODUCTION Interpretation is a communication process used by resource managers to inform the visitor about a resource.... The availability of regularly scheduled programs provided ample opportunity to study interpretation within the system. The need to study personal contact interpretive programs limited the general availability of programs for study, but adequate numbers were...

  8. i1j1K011 CiiHTAKT1'!!iI1 11 CEMAl!Tlt'H Ul Bi'D.3KI1 ME:tllY CY!JEPfiHTYI1W1OHI1C1"KYl1'E H MHor03HAlJmHE

    E-Print Network [OSTI]

    Goranko, Valentin

    rules o f infe Te~ (see [6JJ ': Ax i ont5 : (J) ') (.1J") (]J;) ( R ) (C,) CUr) for i,ti=:l, ...· m- 1

  9. Cotton Could Clean Up Toxic Oil Spills, Say Texas Tech Researchers -India West: Global Indian http://www.indiawest.com/news/global_indian/cotton-could-clean-up-toxic-oil-spills-say-texas-tech/article_5737b73a-404f-11e4-b1d6-d3b81a397f39.html[9/22/2014 8:1

    E-Print Network [OSTI]

    Rock, Chris

    Cotton Could Clean Up Toxic Oil Spills, Say Texas Tech Researchers - India West: Global Indian http://www.indiawest.com/news/global_indian/cotton-could-clean-up-toxic-oil: Cotton Could Clean Up Toxic Oil Spills, Say Texas Tech Researchers Posted: Friday, September 19, 2014 4

  10. Please cite this article in press as: Y.-R. Lou, et al., 25-Hydroxyvitamin D3 is an agonistic vitamin D receptor ligand, J. Steroid Biochem. Mol. Biol. (2009), doi:10.1016/j.jsbmb.2009.11.011

    E-Print Network [OSTI]

    Kalueff, Allan V.

    2009-01-01

    , University of Tampere, Tampere, FIN-33014, Finland4 b Division of Biopharmaceutics and Pharmacokinetics of Clinical Chemistry, Tampere University Hospital, Tampere, FIN-33520, Finland9 10 a r t i c l e i n f o11 12 of Tampere, Tampere, FIN- 33014, Finland. Tel.: +358

  11. Fermilab Map Legend

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Area - C-4 Proton Assembly - C-4 PS2 - D-3 PS3 - C-4 PS4, PE3 - C-4 PS5 - C-4 PSI, PSO - D-3 PW2 - D-3 PW3 - D-3 PW4 - D-3 PW6 - C-4 R Ramsey Auditorium - E-2 Roads & Grounds...

  12. Intrathymic radioresistant stem cells follow an IL-2/IL-2R pathway during thymic regeneration after sublethal irradiation

    SciTech Connect (OSTI)

    Zuniga-Pfluecker, J.C.K.; Kruisbeek, A.M. )

    1990-05-15

    Sublethally irradiated mice undergo thymic regeneration which follows a phenotypic pattern of events similar to that observed during normal fetal development. Thymic regeneration after irradiation is the product of a limited pool of intrathymic radioresistant stem cells undergoing simultaneous differentiation. We show that in this model of T cell development, thymic regeneration follows a pathway in which the IL-2R is transiently expressed on CD4-/CD8- cells. IL-2R expression occurred during the exponential growth period of thymic regeneration, and IL-2R blocking prevented this explosive growth. Flow cytometry analysis revealed that the IL-2R blockade affected primarily the development of the immature CD3-/CD4-/CD8- (triple negative) cells and their ability to generate CD3+/CD4+/CD8+ or CD3+/CD4+/CD8- and CD3+/CD4-/CD8+ thymocytes. Thus, our findings demonstrate that blocking of the IL-2R resulted in an arrest in proliferation and differentiation by intrathymic radioresistant stem cells, indicating that the IL-2/IL-2R pathway is necessary for the expansion of immature triple negative T cells.

  13. Feasibility and preliminary design study for a high velocity, low density wind tunnel utilizing the thermal creep effect 

    E-Print Network [OSTI]

    Stephen, Alton Lee

    1968-01-01

    FE7 SE'BID 1'"Y AND PB I '&NAEY DLS1GN STUDY POR A H. GH V' LOCITY, 10iif DFN ITY BIND UNNEL UT1LI71NG THE THEP". AL CREEP EFFECT A Thesis Alton Lee Steghens, Jr. Submitted to the Graduate College of the Texas AKN University in partial fulf... illment o- the regui ements for the degree NASTEP. 0 SCIENCE Aug st 1968 Yajor Subject: A rospa. e Engineering FEASIBILITY AND PRELIMINARY DESIGN STUDY FOR A HIGH VELOCITY, LOW DENSITY HIND TUNNEL UTILIZING THE THERiMAL CREEP EFFECT A Thesis Alton...

  14. A Study of the Use of a Lossless Lattice for the Synthesis of a Minimum Impedance Function 

    E-Print Network [OSTI]

    Barnard, Herbert Marvin

    1960-01-01

    transformers waa e-? t ablixhed? network theorists have worked on reducing the number of CB) el?ments required for such a realization. Pautell ? Reza( ? and (51 Pialkow and Gerst (independently) discovered a modification of the Bnt t -Duf fin procedure... that reduces the u!ml er of el ements from six to five pet' cycle. If the specified Iunction is a biquadratic mini mum function, seven elements would be required in the modi fled Bott- Duf fin procedure (five elements in the cycle pl!!s twc. I ermi !ation...

  15. Measurement and modeling of uranium and strategic element sorption by amidoxime resins in natural seawater 

    E-Print Network [OSTI]

    Pina-Jordan, Jose Gregorio

    1985-01-01

    -JORDAN Approved as to style and content by: F, A. Best (Chairman of Committee) C. A. Erdman (Head of Department) S. sun aram (Member) Mar R. Scott (Member) Dec. 1985 ABSTRACT Measur ement and modeling of Uranium and Strategic Element Sor ption... by Amidoxime Resins in Natural Seawater . (Dec. 1985) Jose Gregor io Pica-Jordan, B. S. , Texas A&M University Chairman of Advisory Committee: Dr . F. R. Best The international effort to economically recover ur anium and strategic elements from seawater has...

  16. An investigation of the use of lime as a soil additive to modify the detrimental effects of frost action 

    E-Print Network [OSTI]

    Earnest, Clyde Talley

    1959-01-01

    AN INVESTIGATION OF THE USE OF LIME AS A SOIL ADDITIVE TO MODIFI THE DETfEMENTAL EFFECTS OF FROST ACTION GLIDE T. EARNEST~ JR. Captain~ Corps of Engineers Submitted to the Graduate School of the Agricultural and Mechanical College of Texas... in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE August 1959 Ma)or Sub)acts Civil Engineering AN INVESTIGATION OF THE USE OF LIME AS A SOIL ADDITIVE TO MODIFY THE DETRIMENTAL EFFECTS OF FROST ACTION A Thesis CLYDE T...

  17. 10/28/14, 1:55 PMAbstract Print View Page 1 of 3http://www.abstractsonline.com/Plan/AbstractPrintView.aspx?mID=3527&sKe...b-e272-489b-a12e-0392a61363e8&cKey=08ff6a21-cf84-43cb-8608-adf8709d3f11

    E-Print Network [OSTI]

    Shenoy, Krishna V.

    to manipulate a 3 degree of freedom haptic feedback device (delta.3, Force Dimension) fitted with a 3d-printed

  18. Intraoperative Electrochemotherapy of Colorectal Liver Metastases IBRAHIM EDHEMOVIC, MD, MSc,1

    E-Print Network [OSTI]

    Ljubljana, University of

    MALI, PhD,3 TOMAZ JARM, PhD,3 BOR KOS, PhD,3 DENIS PAVLIHA, PhD,3 BILJANA GRCAR KUZMANOV, MD, PhD,1 Ljubljana, Ljubljana, Slovenia 3 Department of Biomedical Engineering, Faculty of Electrical Engineering

  19. Tea Pigments Inhibit the Production of Type 1 (TH1) and Type 2 (TH2) Helper T Cell Cytokines

    E-Print Network [OSTI]

    Toledo, University of

    , such as those present in green tea have been shown to exhibit cardioprotective and anticarcinogenic effects, catechins from green tea extract, and curcumin from turmeric are potent scavengers of oxygen and lipidTea Pigments Inhibit the Production of Type 1 (TH1) and Type 2 (TH2) Helper T Cell Cytokines in CD4

  20. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents

    E-Print Network [OSTI]

    Levin, Judith G.

    sections. Significant updates are highlighted throughout the document. New Section Cost Considerations therapy (ART). This new section provides an overview of costs as they relate to adherence, including-associated clinical symptoms; or who develop conditions or initiate therapy that may lead to reduction of CD4 cell

  1. Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells

    SciTech Connect (OSTI)

    Kim, Joon-Young [Cancer Stem Cell Section, Laboratory of Cancer Prevention, NCI-Frederick, 1050 Boyles Street, Building 560, Room 21-78, Frederick, MD 21702 (United States)], E-mail: jykim@ncifcrf.gov; Kim, Han-Jong; Hurt, Elaine M. [Cancer Stem Cell Section, Laboratory of Cancer Prevention, NCI-Frederick, 1050 Boyles Street, Building 560, Room 21-78, Frederick, MD 21702 (United States); Chen, Xin [Basic Research Program, SAIC-Frederick, Inc., NCI-Frederick, MD 21702 (United States); Howard, O.M. Zack [Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702 (United States); Farrar, William L. [Cancer Stem Cell Section, Laboratory of Cancer Prevention, NCI-Frederick, 1050 Boyles Street, Building 560, Room 21-78, Frederick, MD 21702 (United States)], E-mail: farrar@mail.ncifcrf.gov

    2007-10-12

    FOXP3, a forkhead transcription factor is essential for the development and function of CD4{sup +}CD25{sup +} regulatory T cells (Tregs). In contrast to conversion of murine naive T cells to Tregs by transduction of Foxp3, it is controversial whether ectopic expression of FOXP3 in human CD4{sup +} T cells is sufficient for acquisition of suppressive activity. Here, we show that retroviral transduction of FOXP3 induces a Treg phenotype in human leukemic CD4{sup +} Jurkat-T cells, evidenced by increased expression of Treg-associated cell surface markers as well as inhibition of cytokine production. Furthermore, FOXP3-transduced Jurkat-T cells suppress the proliferation of human CD4{sup +}CD25{sup -} T cells. Additionally, DNA microarray analysis identifies Treg-related genes regulated by FOXP3. Our study demonstrates that enforced expression of FOXP3 confers Treg-like properties on Jurkat-T cells, which can be a convenient and efficient Treg-like cell model for further study to identify Treg cell surface markers and target genes regulated by FOXP3.

  2. Improving the Anti-HIV Potency of Different Compounds through Synergy and Covalent Linkage: Dimerization Studies of CXCL8 

    E-Print Network [OSTI]

    Kagiampakis, Ioannis

    2011-10-21

    In the first part of my dissertation we focused on the development of covalently linking compounds that bind gp120 with those that bind gp41 in order to block HIV fusion. We used griffithsin or CD4M33, that both bind to gp120, covalently linked...

  3. www.rsc.org/loc ISSN 1473-0197

    E-Print Network [OSTI]

    Daraio, Chiara

    primary T cells. Spatiotemporally deterministic retrieval of T cell subsets in relation to their migration the capabilities of traditional cell culture and migration assays, and characterized migration of primary human CD4 and gene expression analysis of migrating human T cells Volume 15 Number 5 7 March 2015 Pages 1217­1396 #12

  4. February 2004 | Volume 2 | Issue 2 | Page 0140PLoS Biology | http://biology.plosjournals.org Of the 300 or so viruses that cause

    E-Print Network [OSTI]

    Chuang, Jeffrey

    ://biology.plosjournals.org Of the 300 or so viruses that cause disease in humans,HIV may have the greatest adaptive advantage.Like most the virus.But as the infection progresses, CD4 counts drop and the body's ability to renew T-cells decreases

  5. Quasielastic electron scattering from methane, methane-d4, methane-d2, ethylene, and 2-methylpropane

    E-Print Network [OSTI]

    Hitchcock, Adam P.

    Quasielastic electron scattering from methane, methane-d4, methane-d2, ethylene, and 2-methylpropane, ethylene, methane, and two isotopically substituted methanes, CH2D2 and CD4, at a momentum constituent. For example, Fig. 1 of Ref. 2 shows that, for gaseous methane, above a certain momentum transfer

  6. 2001 Macmillan Magazines Ltd 60 | JANUARY 2002 | VOLUME 2 www.nature.com/reviews/immunol

    E-Print Network [OSTI]

    MacDonald, Andrew

    ., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor -chains (CD25). Breakdown of a single mechanism of self- tolerance causes various autoimmune diseases. J. Immunol. 155, 1151­1164 (1995). 81. Groux, H. et al. A CD4+ T-cell subset inhibits

  7. Agrawal A, Wetherill L, Dick DM, Xuei X, Hinrichs A, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Bierut LJ, Edenberg HJ, Foroud T. Evidence for association

    E-Print Network [OSTI]

    Oliver, Douglas L.

    18618593) Chhabra A. MHC class I TCR engineered anti-tumor CD4 T cells: implications for cancer, Morgan TR, Sterling RK, Wagner DA, Desanto JL, Curto TM, Wright EC, HALT-C Trial Group. Quantitative, Bonkovsky HL, Naishadham D, Dienstag JL, Sterling RK, Lok AS, Su GL, Halt- C Trial Group. Serum fibrosis

  8. The selective effect of dietary n-3 polyunsaturated fatty acids on murine Th1 and Th2 cell development 

    E-Print Network [OSTI]

    Zhang, Ping

    2006-10-30

    To examine how dietary n-3 polyunsaturated fatty acids affect Th2 cell development, female C57BL/6 mice were fed a washout corn oil (CO) diet for 1 wk followed by 2 wk of either the same CO diet or a fish oil (FO) diet. CD4+ T cells were isolated...

  9. ENERGY, CLIMATE AND SUSTAINABLE

    E-Print Network [OSTI]

    OUNtries: a Perspective from southern africa . . . . . . . . . . 33 WashingtonZhakata aN Observer's PersDenmark,theNetherlandsMinistryofForeignAffairs,nortotherespectiveorganizationsofeachindividualauthor. CapacityDevelopmentforCDM(CD4CDM)Project UNEPRisøCentre, RisøNationalLaboratoryforSustainableEnergy Thetherewereabout5000projectsinthe pipeline,whichwereprojectedtogenerateatotal issuanceof1.2billiontonnesof

  10. 336 IEEE TRANSACTIONS ON AUTOMATIC CONTROL, VOL. 48, NO. 2, FEBRUARY 2003 VI. CONCLUSION

    E-Print Network [OSTI]

    Qu, Zhihua

    In this note, we have studied different concepts of nonlinear iden- tifiability in the linear algebraic: An Algebraic Setting. London, U.K.: Springer-Verlag, 1999. [3] Á Császár, General Topology. New York: Adam. M. Leonard, and M. Markowitz, "Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1

  11. Pb exposure attenuates hypersensitivity in vivo by increasing regulatory T cells

    SciTech Connect (OSTI)

    Fang, Liang; Zhao, Fang; Shen, Xuefeng; Ouyang, Weiming; Liu, Xinqin; Xu, Yan; Yu, Tao; Jin, Boquan; Chen, Jingyuan; Luo, Wenjing

    2012-12-01

    Pb is a common environmental pollutant affecting various organs. Exposure of the immune system to Pb leads to immunosuppression or immunodysregulation. Although previous studies showed that Pb exposure can modulate the function of helper T cells, Pb immunotoxicity remains incompletely understood. In this study, we investigated the effect of Pb exposure on T cell development, and the underlying mechanism of Pb-induced suppression of the delayed-type hypersensitivity (DTH) response in vivo. Sprague–Dawley rats were exposed to 300 ppm Pb-acetate solution via the drinking water for six weeks, and we found that Pb exposure significantly increased Pb concentrations in the blood by 4.2-fold (p < 0.05) as compared to those in the control rats. In Pb-exposed rats, the amount of thymic CD4{sup +}CD8{sup ?} and peripheral CD4{sup +} T cells was significantly reduced, whereas, CD8{sup +} population was not affected. In contrast to conventional CD4{sup +} T cells, Foxp3{sup +} regulatory T cells (Tregs) were increased in both the thymus and peripheral lymphoid organs of Pb-exposed rats. In line with the increase of Tregs, the DTH response of Pb-exposed rats was markedly suppressed. Depletion of Tregs reversed the suppression of DTH response by Pb-exposed CD4{sup +} T cells in an adoptive transfer model, suggesting a critical role of the increased Tregs in suppressing the DTH response. Collectively, this study revealed that Pb-exposure may upregulate Tregs, thereby leading to immunosuppression. -- Highlights: ? Pb exposure impaired CD4{sup +} thymic T cell development. ? Peripheral T lymphocytes were reduced following Pb exposure. ? Pb exposure increases thymic and peripheral Treg cells in rats. ? Tregs played a critical role in Pb-exposure-induced immune suppression.

  12. Name: ____________________________________ Instructions

    E-Print Network [OSTI]

    California at San Diego, University of

    = parity reconstructed from d; dr = corrected d Let cx = cr ^ c = syndrome cr[0] = d[3]^d[1]^d[0], cr[1] = d[3]^d[2]^d[0], cr[2] = d[3]^d[2]^d[1]. dr*3+ = d*3+ ^ (cx==3'b111) dr*2+ = d*2+ ^ (cx==3'b100) dr*1+ = d*1+ ^ (cx==3'b010) dr*0+ = d*0+ ^ (cx==3'b001) c. How many errors can you design detect, and how

  13. TARM1 is a novel LRC-encoded ITAM receptor 1 that co-stimulates pro-inflammatory 2 cytokine secretion by macrophages and neutrophils

    E-Print Network [OSTI]

    Radjabova, Valeria; Mastroeni, Piero; Skjødt, Karsten; Zaccone, Paola; de Bono, Bernard; Goodall, Jane C.; Chilvers, Edwin R.; Juss, Jatinder K.; Jones, Des C.; Trowsdale, John; Barrow, Alexander David

    2015-07-29

    longer than previously appreciated, can undergo 84 reverse transmigration, display plasticity and functional and phenotypic heterogeneity (13) (14). 85 There is compelling evidence that neutrophils engage in bi-directional interactions with a variety 86... incubation at 37 ?C, DMSO was used to dissolve formazan 308 crystals and absorbance (570 nm) was measured on a Synergy HT plate reader. Human T cells 309 were isolated from peripheral blood of healthy donors (n=2) using CD4+ positive selection 310 magnetic...

  14. Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling

    SciTech Connect (OSTI)

    Forward, Nicholas A.; Conrad, David M.; Power Coombs, Melanie R.; Doucette, Carolyn D.; Furlong, Suzanne J.; Lin, Tong-Jun; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia ; Hoskin, David W.

    2011-04-22

    Highlights: {yields} Curcumin inhibits CD4{sup +} T-lymphocyte proliferation. {yields} Curcumin inhibits interleukin-2 (IL-2) synthesis and CD25 expression by CD4{sup +} T-lymphocytes. {yields} Curcumin interferes with IL-2 receptor signaling by inhibiting JAK3 and STAT5 phosphorylation. {yields} IL-2-dependent regulatory T-lymphocyte function and Foxp3 expression is downregulated by curcumin. -- Abstract: Curcumin (diferulomethane) is the principal curcuminoid in the spice tumeric and a potent inhibitor of activation-induced T-lymphocyte proliferation; however, the molecular basis of this immunosuppressive effect has not been well studied. Here we show that micromolar concentrations of curcumin inhibited DNA synthesis by mouse CD4{sup +} T-lymphocytes, as well as interleukin-2 (IL-2) and CD25 ({alpha} chain of the high affinity IL-2 receptor) expression in response to antibody-mediated cross-linking of CD3 and CD28. Curcumin acted downstream of protein kinase C activation and intracellular Ca{sup 2+} release to inhibit I{kappa}B phosphorylation, which is required for nuclear translocation of the transcription factor NF{kappa}B. In addition, IL-2-dependent DNA synthesis by mouse CTLL-2 cells, but not constitutive CD25 expression, was impaired in the presence of curcumin, which demonstrated an inhibitory effect on IL-2 receptor (IL-2R) signaling. IL-2-induced phosphorylation of STAT5A and JAK3, but not JAK1, was diminished in the presence of curcumin, indicating inhibition of critical proximal events in IL-2R signaling. In line with the inhibitory action of curcumin on IL-2R signaling, pretreatment of CD4{sup +}CD25{sup +} regulatory T-cells with curcumin downregulated suppressor function, as well as forkhead box p3 (Foxp3) expression. We conclude that curcumin inhibits IL-2 signaling by reducing available IL-2 and high affinity IL-2R, as well as interfering with IL-2R signaling.

  15. NSTX-U NSTX-U PAC-36 1 PAC-36 Agenda June 23, 2015

    E-Print Network [OSTI]

    Princeton Plasma Physics Laboratory

    HHFW System 1st NBI 2nd NBI NSTX-U · 1 shot away from 1st plasma attempt, had arc on OH water cooling-40 minutes #12;M. Ono NSTX-U PAC-36 June 23, 2015NSTX-U NSTX-U OH Arc Incident / Facility Status Masa Ono, we were performing test shots in preparation for the CD-4 KPP attempt when an arc occurred. 3

  16. The role of CCL5 (RANTES) in the immune response against Mycobacterium tuberculosis in the guinea pig 

    E-Print Network [OSTI]

    Skwor, Troy Arthur

    2005-02-17

    Page 1 Ranking of Tuberculous Pleurisy Post-4 Days Induction...................................105 2 Primers Used for Real-time PCR ........................................................................117 3 Scoring of Granulomas 4... for the host phagocytes to release cytokines favoring the differentiation of CD4+ T helper cells into Th1 effector cells. The production of IL-12, IL-18, and IL-23 are pivotal in this step. These cytokines induce naive and memory T lymphocytes to release...

  17. Michigan State of the State 51 Weight Variable: statewt

    E-Print Network [OSTI]

    Riley, Shawn J.

    1 Most Important Problem 9 PO1 Obama Rating 11 PO2 Granholm Rating 11 P4a Issue Governor Companies Less Likely Lay Off 30 sm5 Self Employed Make Good Living 31 sm6 Source Information Start Business Factor: Close Family/Friends 49 CD1 Sex 49 CD2 Year Born 50 CD3 Education Level 52 CD5a Ethnicity 53 CD4

  18. Vitamin D designates a group of calcitriols, fat solu ble hormones of secosteroid nature [1 3]. The calcitriols

    E-Print Network [OSTI]

    Kalueff, Allan V.

    Vitamin D designates a group of calcitriols, fat solu ble hormones of secosteroid nature [1 3]. The calcitriols include vitamins D2, D3, D4, D5, and their derivatives [3]. Vitamin D3 (cholecalciferol, 4]. Vitamin D3 itself is biologi cally inert, and its bioactivation involves double hydroxy lation

  19. Callosal Tissue Loss in Multiple System Atrophy--A One-Year Follow-Up Study

    E-Print Network [OSTI]

    Thompson, Paul

    ,2 * Eileen Lu¨ders, PhD,3 Karsten Specht, PhD,4,5 Ju¨rgen Ruhlmann, MD,6 Nicole Schimke, MD,7 Paul M. Thompson, PhD,3 Yi Y. Chou, MS,3 Arthur W. Toga, PhD,3 Michael Abele, MD,2 Ullrich Wu¨llner, MD,2

  20. Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Pan, Ruimin; Chen, Yuxin; Vaine, Michael; Hu, Guangnan; Wang, Shixia; Lu, Shan; Kong, Xiang -Peng

    2015-07-15

    The fourth conserved region (C4) in the HIV-1 envelope glycoprotein (Env) gp120 is a structural element that is important for its function, as it binds to both the receptor CD4 and the co-receptor CCR5/CXCR4. It has long been known that this region is highly immunogenic and that it harbors B-cell as well as T-cell epitopes. It is the target of a number of antibodies in animal studies, which are called CD4-blockers. However, the mechanism by which the virus shields itself from such antibody responses is not known. Here, we determined the crystal structure of R53 in complex with its epitopemore »peptide using a novel anti-C4 rabbit monoclonal antibody R53. Our data show that although the epitope of R53 covers a highly conserved sequence 433AMYAPPI439, it is not available in the gp120 trimer and in the CD4-bound conformation. Our results suggest a masking mechanism to explain how HIV-1 protects this critical region from the human immune system.« less

  1. Closeout of the Melton Valley Completion Project at the Oak Ridge National Laboratory

    SciTech Connect (OSTI)

    Bonilla, R.; Johnson, Ch. [Bechtel Jacobs Company, LLC, Oak Ridge, TN (United States); Skinner, R. [U.S. DOE, Oak Ridge Operations Office, Oak Ridge, TN (United States); Adams, V. [U.S. DOE, Office of Groundwater and Soil Remediation, Washington, DC (United States)

    2008-07-01

    The U.S. Department of Energy DOE Order 413.3A (Program and Project Management for the Acquisition of Capital Assets) identifies major milestones in a project life cycle that require approval upon achievement, including Critical Decision-4 (CD-4), the project completion milestone. A CD-4 document is required for all DOE projects in accordance with DOE Order 413.3A, Program and Project Management for Acquisition of Capital Assets. A conditional CD-4 report was prepared for the Melton Valley Completion Project (MVCP) in order to document the completion of the remedial action in the Melton Valley watershed. Approval of the MVCP CD-4 was 'conditional' pending final resolution of a small quantity of unexpected pyrophoric material, with no current disposition pathway, remaining in one of the waste trenches that were to be remediated as part of the completion project. This paper will provide an overview of the MVCP remediation work and the process successfully used to demonstrate closeout of a major CERCLA project in accordance with DOE requirements. In summary: The MV ROD was planned to be completed in 12 years; however, under the ACP the remedial activities were completed 6 years ahead of schedule (September 2006). Highlights of the remedial actions include: - Completion of remedial action activities at 219 release sites identified in the MV ROD. - Construction of 58 hectares of multilayer caps for SWSA 4, SWSA 5, SWSA 6, Pits 2, 3 and 4 and Trenches 5, 6, and 7; - Complete excavation, retrieval and over-pack of 204 casks, 8 boxes, and 530 m{sup 3} of loose waste from the TRU waste retrieval project; - Complete demolition and disposition of approx. 557 m{sup 2} of various buildings such as HRE ancillary facilities, NHF, Liquid LLW pumping stations, 7841 Scrap Yard, misc. storage buildings, and well P and A; - Removal of LLW sludges and stabilization of T-1, T-2, and HFIR tanks; - In situ grouting/stabilization of approx. 12 km of inactive waste pipelines; - Excavation and disposition of approx. 38,000 m{sup 3} of soil from HFIR impoundments, HRE cryogenic pond, IHP and contaminated soil from miscellaneous leak sites; - Completion of in-situ grouting of LLLW matrix at Trenches 5 and 7. The CD-4 document to demonstrate attainment of the project completion milestone was prepared to document close-out activities. Approval of the MVCP CD-4 was obtained but deemed 'conditional' pending final resolution of a small quantity of unexpected pyrophoric material, with no current disposition pathway, remaining in Trench 13 of the 22 Trench Area in SWSA 5N. DOE is currently evaluating options for the final disposition of this material and has committed to resolution of the issue by the end of Fiscal Year 2008. At that time, all aspects of the Melton Valley Completion Project will be complete. (authors)

  2. He proton spectra for diagnosing shell R and fuel Ti of imploded capsules at OMEGA

    E-Print Network [OSTI]

    D­3 He proton spectra for diagnosing shell R and fuel Ti of imploded capsules at OMEGA C. K. Li, D the first use of 14.7 MeV deuterium­helium3 (D­3 He) proton spectra for diagnosing shell areal density ( R the conditions achieved by these implosions, we utilize, in large part, the 14.7 MeV protons generated from D­3

  3. Date: August 20, 2014 SCHOOL OF MEDICINE IN NEW ORLEANS

    E-Print Network [OSTI]

    Vice Chair 3 2012 Medicine Carmen Canavier, PhD 3 2006 CBA Jesus Lovera, MD 2 2008 Neurology Pam Houhui Xia, PhD 3 2010 CBA/NSC June Liu, PhD 2 2011 CBA Ludmila Belayev, MD 2 2011 Neurosurgery/NSC Minghao Jin, PhD 2 2012 Ophthalmology/NSC YaPing Tang, PhD 3 2012 CBA David Worthylake, PhD 2 2012

  4. Bekenstein-Spectrum, Hawking-Temperature and Specific Heat of Schwarzschild Black Holes from Microscopic Chains

    E-Print Network [OSTI]

    Axel Krause

    2005-10-28

    We study the thermodynamic consequences of a recently proposed description for a Schwarzschild black hole based on Euclidean (D3,D3)+(\\bar{D3},\\bar{D3}) brane pairs described in terms of chain-like excitations. A discrete mass-spectrum of Bekenstein-type is inferred and upon identification of the black hole mass with the chain's energy the leading corrections to both Hawking-temperature and specific heat of the black hole are obtained. The results indicate that for small black holes the evaporation process will be considerably altered.

  5. Vrme-och strmningsteknik Processteknikens grunder (PTG) 2010

    E-Print Network [OSTI]

    Zevenhoven, Ron

    hastighet, v1 = 5·z m/s, genom ett rör med diametern D1= (z + c) cm in i ett annat rör med diametern D3 = (3

  6. Vitamin D, parathyroid hormone levels and bone mineral density in community-dwelling older women: The Rancho Bernardo Study

    E-Print Network [OSTI]

    von Mühlen, Denise G; Greendale, Gail A; Garland, Cedric F; Wan, Lori; Barrett-Connor, Elizabeth

    2005-01-01

    Effect of four monthly oral vitamin D3 (cholecalciferol)A, Pedersen, JI (2002) Can vitamin D supplementation reduceHolick, MF (1998) Redefining vitamin D insufficiency. Lancet

  7. The ExoVM System for Automatic VM and Application Reduction

    E-Print Network [OSTI]

    Titzer, B L; Joshua Auerbach; David F. Bacon; Palsberg, J

    2007-01-01

    Mulchandani, Java for embedded systems," Internet Computing,Systems]: Real-time and embedded systems; D.3.2 [Programmingfor deployment on embedded systems," Sci. Comput. Program. ,

  8. An experimental and numerical study of wind turbine seismic behavior

    E-Print Network [OSTI]

    Prowell, I.

    2011-01-01

    3.2.1 Description of Test Wind Turbine . . . . . .Figure 1.2: Components of a modern wind turbine . . . . . .D.3: D.4: Wind turbine parameters . . . . . . . . . . . .

  9. Financial Analysis of Incentive Mechanisms to Promote Energy Efficiency: Case Study of a Prototypical Southwest Utility

    E-Print Network [OSTI]

    Cappers, Peter

    2009-01-01

    costs of energy and capacity . 73 Table C- 3.costs of energy and capacity 82 Table D- 3.return of avoided energy and capacity costs Figure ES- 1.

  10. LncRNA Expression Discriminates Karyotype and Predicts Survival in B-Lymphoblastic Leukemia

    E-Print Network [OSTI]

    2015-01-01

    Malave 1,2* , Ella V. Waters 1 , Weihong Yan, Ph.D. 3 ,doxorubicin dissolved in water) for 24 hours, then harvested

  11. Instrumentation upgrades for the Macromolecular Crystallography...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    322 Martin Fuchs, MX Group, Swiss Light Source; Paul Scherrer Institute (Villigen, Switzerland) A new unified diffractometer - the D3 - has been developed for the three MX...

  12. Reliable and Efficient Programming Abstractions for Wireless Sensor Networks

    E-Print Network [OSTI]

    Kothari, Nupur; Gummadi, Ramakrishna; Millstein, Todd; Govindan, Ramesh

    2007-01-01

    systems languages, and parallel programming languages.present the Pleiades programming language, its compiler, andprogramming; D.3.2 [Programming Languages]: Language Classi?

  13. Detecting regular sound changes in linguistics as events of concerted...

    Office of Scientific and Technical Information (OSTI)

    other evolving group. less Authors: Hruschka, Daniel J. 1 ; Branford, Simon 2 ; Smith, Eric D. 3 ; Wilkins, Jon 4 ; Meade, Andrew 2 ; Pagel, Mark 5 ; Bhattacharya,...

  14. Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification

    E-Print Network [OSTI]

    Lyons, Paul A.; Koukoulaki, Maria; Hatton, Alexander; Doggett, Karen; Woffendin, Hayley B.; Chaudhry, Afzal N.; Smith, Kenneth G. C.

    2007-03-05

    . Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, Shark KB, Grande WJ, Hughes KM, Kapur V, Gregersen PK, Behrens TW: Interferon-inducible gene expression signature 12. Bennett L, Palucka AK, Arce E, Cantrell V, Borvak J, Banchereau J... plasma cells in peripheral blood and their clinical significance. Br J Haema- tol 1996, 92:184-191. 17. Stanciu LA, Shute J, Holgate ST, Djukanovic R: Production of IL-8 and IL-4 by positively and negatively selected CD4+ and CD8+ human T cells following...

  15. Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein

    E-Print Network [OSTI]

    Kassa, Aemro; Dey, Antu K.; Sarkar, Pampi; Labranche, Celia; Go, Eden P.; Clarck, Danile F.; Sun, Yide; Nandi, Avishek; Hartog, Karin; Desaire, Heather; Montefiori, David; Carfri, Andrea; Srivastava, Indresh K.; Barnett, Susan W.

    2013-10-13

    , and reproduction in any medium, provided the original author and source are credited. Funding: This study was supported by the NIAID-NIH HIV Vaccine Research and Design (HIVRAD) grant # 5P01 AI066287. The funders had no role in study design, data collection...-mediated neutralization. Recent high-resolution gp120 structures [5,6] have revealed the complete structure of the inner domain of HIV-1 gp120 that was missing from previous studies [7–10]. These structures showed that the inner domain of gp120 in CD4-bound state...

  16. Evaluation of microencapsulation as an improved vaccination strategy against brucellosis 

    E-Print Network [OSTI]

    Arenas Gamboa, Angela Maria

    2009-05-15

    imunized with Escherichia coli expresing Brucela bortus Cu/Zn superoxide-ismutase. Animals that recived the vacine, wer able to elicit protective imunity aginst B. abortus wild-type chalenge and when splenocytes wer separted into CD4 + and CD8.../VpB shel). Control groups recived 1x0 5 CFU of either (a) noencapsulated luxR:Tn5, (b) Empty capsules (no bacteria entraped) or (c) two hundre microliters of MOPS bufer. Evalution f Brucela specif antibody. To detrmine anti...

  17. Prenatal cadmium exposure produces persistent changes to thymus and spleen cell phenotypic repertoire as well as the acquired immune response

    SciTech Connect (OSTI)

    Holásková, Ida; Elliott, Meenal; Hanson, Miranda L.; Schafer, Rosana [Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506 (United States)] [Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506 (United States); Barnett, John B., E-mail: jbarnett@hsc.wvu.edu [Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506 (United States); Mary Babb Randolph Cancer Center, West Virginia University School of Medicine, Morgantown, WV 26506 (United States)

    2012-12-01

    Cadmium (Cd) is a common environmental contaminant. Adult exposure to Cd alters the immune system, however, there are limited studies on the effects of prenatal exposure to Cd. Pregnant C57Bl/6 mice were exposed to an environmentally relevant dose of CdCl{sub 2} (10 ppm) and the effects on the immune system of the offspring were assessed at 20 weeks of age. Prenatal Cd exposure caused an increase in the percent of CD4{sup ?}CD8{sup ?}CD44{sup +}CD25{sup ?} (DN1) thymocytes in both sexes and a decrease in the percent of CD4{sup ?}CD8{sup ?}CD44{sup ?}CD25{sup +} (DN3) thymocytes in females. Females had an increase in the percent of splenic CD4{sup +} T cells, CD8{sup +} T cells, and CD45R/B220{sup +} B cells and a decrease in the percent of NK cells and granulocytes (Gr-1{sup +}). Males had an increase in the percent of splenic CD4{sup +} T cells and CD45R/B220{sup +} B cells and a decrease in the percent of CD8{sup +} T cells, NK cells, and granulocytes. The percentage of neutrophils and myeloid-derived suppressor cells were reduced in both sexes. The percent of splenic nTreg cells was decreased in all Cd-exposed offspring. Cd-exposed offspring were immunized with a streptococcal vaccine and the antibody response was determined. PC-specific serum antibody titers were decreased in Cd exposed female offspring but increased in the males. PspA-specific serum IgG titers were increased in both females and males compared to control animals. Females had a decrease in PspA-specific serum IgM antibody titers. Females and males had a decrease in the number of splenic anti-PspA antibody-secreting cells when standardized to the number of B cells. These findings demonstrate that very low levels of Cd exposure during gestation can result in long term sex-specific alterations on the immune system of the offspring. -- Highlights: ? Prenatal exposure to cadmium alters the immune system of 20 week old offspring. ? The percentage of DN1 and DN3 thymocytes was changed. ? Males and females had changed percentages of numerous splenic cell populations. ? The antibody response of a streptococcal vaccine showed numerous changes.

  18. Soil and Groundwater Cleanup - In-Situ Grouting, Lessons Learned (Post

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing Tool FitsProjectDataSecretaryDepartment of EnergyDepartment» Software ToolsCD-4),

  19. Supplemental Information : Secondary Organic Aerosol Production from Modern Diesel Engine Emissions, Shar Samy and1 Barbara Zielinska2

    E-Print Network [OSTI]

    Meskhidze, Nicholas

    Supplemental Information : Secondary Organic Aerosol Production from Modern Diesel Engine Emissions emissions. For more detail on compositional and toxicity changes produced from further29 diesel engine use of Final Mass 05/16/05 D-3, Diesel in Dark with ozone 9:15 11.5 15:30 11 -0.5 0.0 05/17/05 D-3, Diesel

  20. Photovoltaic Energy Conversion

    E-Print Network [OSTI]

    Glashausser, Charles

    Photovoltaic Energy Conversion Frank Zimmermann #12;Solar Electricity Generation Consumes no fuel Electrode Valence Band Conduction Band Fermi Level I- /I3 - Redox Potential Dye 1D 3D* 1D* Energy Levels Counter Electrode Valence Band Conduction Band Fermi Level I- /I3 - Redox Potential Dye 1D 3D* 1D* Energy

  1. Vitamin D Enhances Corneal Epithelial Barrier Function Zhaohong Yin,1

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Vitamin D Enhances Corneal Epithelial Barrier Function Zhaohong Yin,1 Victorina Pintea,1 Yanping contain mRNA for the vitamin D receptor (VDR) and 1 -hydroxylase, the enzyme required to convert 25(OH)D3 to 1,25(OH)2D3, and measured vitamin D metabolite concentra- tions in aqueous and vitreous humor

  2. Proton Irradiation Damage Assessment of Carbon Reinforced Composites

    E-Print Network [OSTI]

    McDonald, Kirk

    Proton Irradiation Damage Assessment of Carbon Reinforced Composites: 2-D & 3-D Weaved Structures. of thermal expansion (CTE). #12;Positive news regarding 3D Carbon composite kept coming !! Irradiation damage-carbon under heavy irradiation (LHC Phase-I collimator material) Phase 2 Expose 2D & 3D carbon

  3. Sets and Constraint Logic Programming Agostino Dovier

    E-Print Network [OSTI]

    Rossi, Gianfranco

    are embedded in a Constraint Logic Programming (CLP) language which provides #12;nite sets|along with basic set by programming in CLP(SET ). Categories and Subject Descriptors: D.3.2 [Programming Languages]: Constraint and Logic Languages; D.3.3 [Programming Languages]: Language Constructs and Features; F.4 [Math- ematical

  4. A Fully Abstract Semantics for a Firstorder Functional Language with Logic Variables

    E-Print Network [OSTI]

    Jagadeesan, Radha

    general, and can be used to give semantics to any constraint­based logic programming languages. Our]: Functional Programming; D.3.1 [Programming Languages]: Formal Definitions and Theory ­ semantics; D.3.2 [Programming Languages]: Dataflow Languages; F.3.2 [Theory of Computation]: Semantics of Programming Languages

  5. US/CERN LHC Accelerator Collaboration DESIGN REPORT

    E-Print Network [OSTI]

    Homes, Christopher C.

    RHIC-type cold mass in a cryostat. The D3 magnets will be built with two single aperture RHIC-type cold acceleration cavities for the two beams. The dipole magnets are designed with a common element: superconducting are designed with one RHIC-style cold mass in a cryostat and the D3 magnets are designed with two such cold

  6. On the Noether Derivation of the Gyrokinetic Energy-Momentum Conservation Laws

    E-Print Network [OSTI]

    On the Noether Derivation of the Gyrokinetic Energy-Momentum Conservation Laws Alain J. Brizard Variational Principles · Gyrokinetic Energy-Momentum Conservation Laws · Gyrokinetic Angular Momentum = - n (d3 x) = - n [( · ) d3 x] #12;· Energy-momentum Conservation Law Infinitesimal space

  7. Human Glucocorticoid-Induced TNF Receptor Ligand Regulates its Signaling Activity Through Multiple Oligomerization States

    SciTech Connect (OSTI)

    Zhou,Z.; Dong, X.; Berezov, A.; Zhang, G.; Li, Y.; Zhang, H.; Murali, R.; Li, B.; Greene, M.

    2008-01-01

    Ligation between glucocorticoid-induced tumor necrosis factor receptor (GITR) and its ligand (GITRL) provides an undefined signal that renders CD4+CD25- effector T cells resistant to the inhibitory effects of CD4+CD25+ regulatory T cells. To understand the structural basis of GITRL function, we have expressed and purified the extracellular domain of human GITR ligand in Escherichia coli. Chromotography and cross-linking studies indicate that human GITRL (hGITRL) exists as dimers and trimers in solution and also can form a supercluster. To gain insight into the nature of GITRL oligomerization, we determined the crystallographic structures of hGITRL, which revealed a loosely associated open trimer with a deep cavity at the molecular center and a flexible C-terminal tail bent for trimerization. Moreover, a tetramer of trimers (i.e., supercluster) has also been observed in the crystal, consistent with the cross-linking analysis. Deletion of the C-terminal distal three residues disrupts the loosely assembled trimer and favors the formation of a dimer that has compromised receptor binding and signaling activity. Collectively, our studies identify multiple oligomeric species of hGITRL that possess distinct kinetics of ERK activation. The studies address the functional implications and structural models for a process by which hGITRL utilizes multiple oligomerization states to regulate GITR-mediated signaling during T cell costimulation.

  8. Wenn Z irgendeine Funktion der Variablen x und y und deren Differentiale involvie-renden Gren p, q, r, s etc. ist, sodass ihr Differential von dieser Art ist

    E-Print Network [OSTI]

    dx2 ddR - y dx2 d3 R, S d4y dx3 = S d3y dx3 - ddy dx3 dS + dy dx3 ddS - y dx3 d3 S - y dx3 d4 S etcR dx3 + d4S dx4 - etc. + y P - dQ dx + ddR dx2 - d3S dx3 + etc. + dy dx Q - dR dx + ddS dx2 - etc aber notwendig, dass für x = a diesen Gleichungen Genüge geleistet wird: P - dQ dx + ddR dx2 - d3S dx3

  9. Anomaly of Tensionless String in Light-cone Gauge

    E-Print Network [OSTI]

    Kenta Murase

    2015-03-04

    The classical tensionless string theory has the spacetime conformal symmetry. We expect and require that the quantum tensionless string theory has it too. In the BRST quantization method, the theory has no spacetime conformal anomaly in two dimensions. On the other hand, in the light-cone gauge quantization without the mode expansion, the theory in $D>3$ has the spacetime conformal anomaly in the traceless part of $[\\mathcal{J}^{-I}, \\mathcal{K}^{J}]$ in some operator order. In this paper, we consider a tensionless closed bosonic string in the light-cone gauge and investigate the spacetime conformal anomaly in the theory with the mode expansion. The appearance of the spacetime conformal anomaly in the light-cone gauge is different between the case of $D>3$ and the case of $D=3$ and depends on the choice of the operator order. Therefore we must consider dangerous commutators in the spacetime conformal symmetry of $D>3$ and $D=3$ in each operator order separately. Specifically we calculate dangerous commutators, $[\\mathcal{J}^{-I},\\mathcal{K}^{K}]$ in $D>3$ and $\\tilde{\\mathcal{K}}^{-}\\equiv -i[\\mathcal{J}^{-}, \\tilde{\\mathcal{K}}^{-}]$ and $[\\mathcal{J}^{-}, \\tilde{\\mathcal{K}}^{-}]$ in $D=3$, in two types of the operator order.

  10. A Simple and Efficient Parallel Disk Mergesort

    E-Print Network [OSTI]

    Barve, Rakesh; Vitter, Jeffrey Scott

    2002-01-01

    BT CBCXD1D4D0CT CPD2CS BXÆCRCXCTD2D8 C8CPD6CPD0D0CTD0 BWCXD7CZ C5CTD6CVCTD7D3D6D8 BD CACPCZCTD7CW BWBA BUCPD6DACT BE C2CTABD6CTDD CBCRD3D8D8 CECXD8D8CTD6 BF BD BT D7CWD3D6D8CTD2CTCS DACTD6D7CXD3D2 D3CU D8CWCXD7 D4CPD4CTD6 CPD4D4CTCPD6CTCS CXD2 C8D6D...3CRCTCTCSCXD2CVD7 D3CU D8CWCT BDBDD8CW BTD2D2D9CPD0 BTBVC5 CBDDD1D4D3D7CXD9D1 D3D2 C8CPD6CPD0D0CTD0 BTD0CVD3D6CXD8CWD1D7 CPD2CS BTD6CRCWCXD8CTCRD8D9D6CTD7 B4CBC8BTBT B3BLBLB5B8 CBD8BA C5CPD0D3B8 BYD6CPD2CRCTB8 C2D9D2CT BDBLBLBLB8 BEBFBEDFBEBGBDBA...

  11. Revolving D-branes and Spontaneous Gauge Symmetry Breaking

    E-Print Network [OSTI]

    Iso, Satoshi

    2015-01-01

    We propose a new mechanism of spontaneous gauge symmetry breaking in the world-volume theory of revolving D-branes around a fixed point of orbifolds. In this paper, we consider a simple model of the T6/Z3 orbifold on which we put D3-branes, D7-branes and their anti-branes. The configuration breaks supersymmetry, but the R-R tadpole cancellation conditions are satisfied. A set of three D3-branes at an orbifold fixed point can separate from the point, but when they move perpendicular to the anti-D7-branes put on the fixed point, they are forced to be pulled back due to an attractive interaction between the D3 and anti-D7 branes. In order to stabilize the separation of the D3-branes at nonzero distance, we consider revolution of the D3-branes around the fixed point. Then the gauge symmetry on D3-branes is spontaneously broken, and the rank of the gauge group is reduced. The distance can be set at our will by appropriately choosing the angular momentum of the revolving D3-branes, which should be determined by the...

  12. Molecular analysis and genetic mapping of the rhodopsin gene in families with autosomal dominant retinitis pigmentosa

    SciTech Connect (OSTI)

    Bunge, S.; Wedemann, H.; Samanns, C.; Horn, M.; Schwinger, E.; Gal, A. (Medizinische Universitaet zu Luebeck (Germany)); David, D. (Laboratorio de Genetica Humana, Lisbon (Portugal)); Terwilliger, D.J.; Ott, J. (Columbia Univ., New York, NY (United States)); Born, L.I. van den (The Netherlands Ophthalmic Research Institute, Amsterdam (Netherlands)) (and others)

    1993-07-01

    Eighty-eight patients/families with autosomal dominant retinitis pigmentosa (RP) were screened for rhodopsin mutations. Direct sequencing revealed 13 different mutations in a total of 14 (i.e., 16%) unrelated patients. Five of these mutations (T4K, Q28H, R135G, F220C, and C222R) have not been reported so far. In addition, multipoint linkage analysis was performed on two large families with autosomal dominant RP due to rhodopsin mutations by using five DNA probes from 3q21-q24. No tight linkage was found between the rhodopsin locus (RHO) and D3S47 ([theta][sub max] = 0.08). By six-point analysis, RHO was localized in the region between D3S21 and D3S47, with a maximum lod score of 13.447 directly at D3S20. 13 refs., 1 fig., 2 tabs.

  13. Chemistry & Biology Natural and Nonnatural Vitamin Ds Compared

    E-Print Network [OSTI]

    Chemistry & Biology 1266 Natural and Nonnatural Vitamin Ds Compared with the Protein-Bound Vitamin Structures of the active vitamin D metabolite 1,25(OH)2D3 (A), the related synthetic agonist LG190155 (B

  14. The Effect of Vitamin D Deficiency on Periodontal Inflammation

    E-Print Network [OSTI]

    Warda, Sherif

    2015-01-01

    Systemic Vitamin K2 and Vitamin D3 on Gingival InflammationGuillot, Xavier, et al. "Vitamin D and inflammation." Joint12. Holick, Michael F. "Vitamin D deficiency." New England

  15. Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly men

    E-Print Network [OSTI]

    2010-01-01

    6):556–562 Bikle DD (2004) Vitamin D and skin cancer. J NutrSundberg JP, Welsh J (2002) Vitamin D(3) receptor ablationbetween serum 25(OH) vitamin D levels and non-melanoma skin

  16. Minireview: vitamin D receptor: new assignments for an already busy receptor.

    E-Print Network [OSTI]

    Norman, Anthony W

    2006-01-01

    of the nuclear receptor for vitamin D bound to its naturalNorman AW 2005 1 ? ,25(OH) 2 -Vitamin D 3 mediated rapid andJW, Glorieux FH, eds. Vitamin D. 2nd ed. San Diego: Elsevier

  17. Localized light orbitals: Basis states threedimensional photonic crystal microscale circuits Hiroyuki Takeda, Alongkarn Chutinan, Sajeev John

    E-Print Network [OSTI]

    John, Sajeev

    , three­dimensional #3D# scattering, micro­ structures enable unprecedented forms optical waveguiding'' reconstruct electromagnetic waveguiding bulk two­ dimensional materials, 2D­3D heterostructures composed PBG # demonstrate utility three­dimensional optical Wannier functions #WF's# for quantitative description

  18. Engineering geology of a mudslide at Bracebridge Inlet, Bathurst Island, Northwest Territories, Canada 

    E-Print Network [OSTI]

    Mayer, Terry Ann

    1980-01-01

    AdoIoaB:qoaCqnS uoCeN OGeI uaq??0 30N3IDS 30 'd3lSW J. o aaubap aqua uog quamautnbau aug go guamIIIJ Ing Ieigued ui EgIswancuO gIIy sexal go a5a IIog aq. enpeuB aqua oy paggteqnS 'd3MIN NNV ld'd3J. slsaqJ VQ'dN'd0 ' S3IKIQJI'd'd3l iS3MHJ. 'd... possible through the kindness of the Terrain Sciences Division of the Geological Survey of Canada. Mr. Fred Alt and the Polar Continental Shelf Project, Depart- ment of Energy, Mines, and Resources of Canada, provided logistical support. Dr. Larry Dyke...

  19. REPRESENTATION TYPES AND 2-PRIMARY HOMOTOPY ...

    E-Print Network [OSTI]

    min(28,?(m ? 215 ? 214 ? 211 ? 19) + 12) m ? 3 mod 8 ... Note that the numbers m0 = 17, 19, 29, and 23 which occur in ?(m ? m0 ? 2L) ...... Z2(B2 + B5) d = 3.

  20. Structural insights into the enzymes of the serine and biotin biosynthetic pathways in mycobacterium tuberculosis 

    E-Print Network [OSTI]

    Dey, Sanghamitra

    2009-05-15

    biosynthetic pathways for Mtb survival. In this study, enzymes from these pathways were characterized using X-ray crystallographic and biochemical studies. D-3-phosphoglycerate dehydrogenase (PGDH) catalyzes the first step of phosphorylated serine biosynthesis...

  1. Fully kinetic numerical modeling of a plasma thruster

    E-Print Network [OSTI]

    Szabo, James Joseph, 1969-

    2001-01-01

    A Hall effect plasma thruster with conductive acceleration channel walls was numerically modeled using 2D3V Particle-in-Cell (PIC) and Monte-Carlo Collision (MCC) methodolo- gies. Electron, ion, and neutral dynamics were ...

  2. Index to stations Grid ZonesStation & facilities Grid Station & facilities ZonesStation & facilities Grid ZonesStation & facilities Grid ZonesStation & facilities Grid ZonesStation & facilities Grid ZonesStation & facilities

    E-Print Network [OSTI]

    Russo, Bernard

    Road Peckham Á ø D4 Queensway Á ______________________________ D3 Ravenscourt Park Á B2 Rayners Lane Y Canada Water Á ( ) § { D7 Canary Wharf § Á ( ) { D8 Canning Town Á ( ) § { D6 Cannon Street ( ) * B7

  3. Advances in three-dimensional rapid prototyping of microfluidic devices for biological applications

    E-Print Network [OSTI]

    Chang, Hsueh-Chia

    . #12;2 Abstract The capability of 3D printing technologies for direct production of complex 3D 3D printing technologies and direct internal 3D laser writing fabrication methods. Current

  4. Letters to Analytical Chemistry Silver Nanoparticles on a Plastic Platform for

    E-Print Network [OSTI]

    Brolo, Alexandre G.

    MNPs suspended in a liquid phase suffers from the inherent stability issues related to the colloidal of nanoparticle's size, shape, and material.1d,3 Suspensions of metallic nanoparticles (MNPs), especially Au NPs

  5. Unification and explanation in early Kaluza-Klein theories

    E-Print Network [OSTI]

    Muntean, Ioan Lucian

    2009-01-01

    attraction (Newton’s gravitation law). 251 D=3 because someand gravitation and not a specific phenomenon. The explananda, as we will see later are laws,law (this is the case with EM and electroweak theory). But gravitation

  6. 2011-VPFA-02, January 2013 Page | 1 Effective Date: January 1, 2011 Prepared by: Business Office

    E-Print Network [OSTI]

    to grant insurance in countries where economic sanctions have been imposed. It is important to look a trip abroad: http://www.international.gc.ca/sanctions/index.aspx?lang=eng&view=d 3.2 Private automobile

  7. CRICKET V2.0 NETWORKS AND MOBILE SYSTEMS GROUP

    E-Print Network [OSTI]

    (£¦§¡¡T#hi$¨§FU0&UV ©"§ f ¡£¦UTa¥2¡¨§1bX8¨#©£¦¤§¡¨TU¦#3©"%£¦¥¨i©"$I#Y0s3(¡90Uf6T#§#¡¨TUD5g£¦¥2 d@3x'3%h

  8. Fast Floating-Point Processing in Common Lisp RICHARD J. FATEMAN

    E-Print Network [OSTI]

    Fateman, Richard J.

    computing environments including symbolic mathematics sys- tems, numerical computing, and graphics. CategoriesandSubjectDescriptors: G.4 Mathematicsof Computing]: MathematicalSoftware{ e ciency, portability D.3 computation, Numerical algorithms 1. INTRODUCTION The combination of symbolic and numeric computation has

  9. DC Discharge Studies Using PIC-MCC: PIC Simulations Jeff Hammel & John Verboncoeur

    E-Print Network [OSTI]

    Wurtele, Jonathan

    DC Discharge Studies Using PIC-MCC: PIC Simulations Jeff Hammel & John Verboncoeur Electronics PIC Simulations (XPDP1) XPDP1, a 1D-3V PIC-MCC code (Verboncoeur et al., 1993), was used to simu- late

  10. For Immediate release: 03/21/12 Contact: Ingrid Wright

    E-Print Network [OSTI]

    Ward, Karen

    , and even clothing. Participating students will also build displays and memory/computer tablets using 2D/3D printing strategies. The cooperative program includes study abroad for MME students from UTEP and Seokyeong

  11. PURDUE UNIVERSITY STUDY GUIDE FOR INTERMEDIATE ...

    E-Print Network [OSTI]

    4. When you feel you are prepared for it, take the sample examination. 5. When you believe your ... —5:z:+25 (1%:122 - gig-25 D. 3:2 - gz+25. E. None of these.

  12. D i s c u s s i o n Discussion2 3Discussion

    E-Print Network [OSTI]

    Yamamoto, Hirosuke

    #12;15 15 MRICT 6 CO2 Conference on Supercritical Fluids- Best Student Poster Award Eriko ShimodaM2 44 M2 22 D3 2 1

  13. Department of Computer Science University of North Carolina at Chapel Hill August 2007 The Challenge

    E-Print Network [OSTI]

    Pollefeys, Marc

    The Challenge Fluid phenomena play important roles in everyday life --- as blowing winds, jet streams, chemical on a Pentium D 3.4GHz processor with 2 GB of RAM. Our fluid simulation using RDS runs in real time

  14. The Differential Effects of Buprenorphine and Methadone on Adolescent Mice. 

    E-Print Network [OSTI]

    Barwatt, Joseph

    2013-03-01

    receptors in adolescent mice. The D2/D3 dopamine receptor may mediate long-term mental changes in adolescents, specifically changes linked to mood and psychotic disorders. Thus, this study examined whether buprenorphine and methadone alter the responses...

  15. Application for use of BPA Right-of-Way

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    foreign line crosses more than one BPA line use additional sheets. BPA Str No. d 3 F POLES LENGTH DEPTH SET CLASS POLE POLE 1 POLE 1 POLE 2 F I X T U R E S SIZE OF CROSSARMS...

  16. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

    SciTech Connect (OSTI)

    Wu, Xueling; Zhou, Tongqing; Zhu, Jiang; Zhang, Baoshan; Georgiev, Ivelin; Wang, Charlene; Chen, Xuejun; Longo, Nancy S.; Louder, Mark; McKee, Krisha; O’ Dell, Sijy; Perfetto, Stephen; Schmidt, Stephen D.; Shi, Wei; Wu, Lan; Yang, Yongping; Yang, Zhi-Yong; Yang, Zhongjia; Zhang, Zhenhai; Bonsignori, Mattia; Crump, John A.; Kapiga, Saidi H.; Sam, Noel E.; Haynes, Barton F.; Simek, Melissa; Burton, Dennis R.; Koff, Wayne C.; Doria-Rose, Nicole A.; Connors, Mark; Mullikin, James C.; Nabel, Gary J.; Roederer, Mario; Shapiro, Lawrence; Kwong, Peter D.; Mascola, John R. (Tumaini); (NIH); (Duke); (Kilimanjaro Repro.); (IAVI)

    2013-03-04

    Antibody VRC01 is a human immunoglobulin that neutralizes about 90% of HIV-1 isolates. To understand how such broadly neutralizing antibodies develop, we used x-ray crystallography and 454 pyrosequencing to characterize additional VRC01-like antibodies from HIV-1-infected individuals. Crystal structures revealed a convergent mode of binding for diverse antibodies to the same CD4-binding-site epitope. A functional genomics analysis of expressed heavy and light chains revealed common pathways of antibody-heavy chain maturation, confined to the IGHV1-2*02 lineage, involving dozens of somatic changes, and capable of pairing with different light chains. Broadly neutralizing HIV-1 immunity associated with VRC01-like antibodies thus involves the evolution of antibodies to a highly affinity-matured state required to recognize an invariant viral structure, with lineages defined from thousands of sequences providing a genetic roadmap of their development.

  17. Determination of amino acids by use of the high frequency titrimeter 

    E-Print Network [OSTI]

    Johnson, John Warren

    1941-01-01

    )oat& ChamiatI. y By yoha 1agem gqhaacaL Ray lAX ]s+l WKSORLZgQR+I ThO WX'LCdl', 1igh08 40 8XpXISS hi@ 43955IN 40 QL'e fyWo QNL0%1 BIO ligsotc@ thia margxeh, far his suggestions sN aeetetanoo oa thhs ~ada CD4 i1L the VOWi810h Ot th%8 tlhMfSy Xatro4... THE TIVRKQU Oy' DISlSXO 4680 kSXDS Titrationo were yerfomed on the, Cibasio anCuo aside within ths frequency ra@go of 58' to Sdt sisaoyolese The NaxiRQu absorption by the dibasic amino acids occurs within this region, as is shown by the Cata and graph...

  18. Zhong, Fengtian He, Guo-Cheng Yuan, Da-Zhi Wang and Chunyu Zeng Yujia Yang, Yukai Liu, Zaicheng Xu, Duofen He, Xiaoqun Zhang, Xiaoyun Hu, Luca Pinello, Dan

    E-Print Network [OSTI]

    Yuan, Guo-Cheng "GC"

    Zhong, Fengtian He, Guo-Cheng Yuan, Da-Zhi Wang and Chunyu Zeng Yujia Yang, Yukai Liu, Zaicheng Xu ; Xiaoqun Zhang, BS1 ; Xiaoyun Hu, MS2 ; Luca Pinello, PhD4 ; Dan Zhong, PhD3 ; Fengtian He, MD, PhD3 ; Guo-Cheng Yuan, PhD4 ; Da-Zhi Wang, PhD2,5 ; Chunyu Zeng, MD, PhD1 1 Dept of Cardiology, Chongqing Institute

  19. 1D AND 2D PIC-MCC SIMULATIONS OF DC DISCHARGES BETWEEN PLANAR ELECTRODES

    E-Print Network [OSTI]

    Wurtele, Jonathan

    1D AND 2D PIC-MCC SIMULATIONS OF DC DISCHARGES BETWEEN PLANAR ELECTRODES Verboncoeur, JV, Hammel in argon and helium (p = 0.1 - 1 Torr; I = 10-6 - 10-2 A) have been simulated using the PIC-MCC methedology using 1d-3v and 2d-3v models. The theory for glow discharges is presented. PIC results are analyzed

  20. Digit Representations Helmut Knaust, Department of Mathematical Sciences, UTEP, El Paso TX 79968

    E-Print Network [OSTI]

    Knaust, Helmut

    ]:= DigitRepresentation fraction_, base_: 10 : Module nr fraction, b, d1, d2, d3, fp, d, pos , b base; d1, nr ; nr b nr; d Append d, IntegerPart nr ; nr nr IntegerPart nr ; ; pos Position fp, nr 1, 1 ; d2 If pos 1, d 1 ;; pos 1 , ; d3 d pos ;; Length d ; Print If b 10, "", " " , d1, ".", If d2 , "", Integer

  1. How to Calculate Your Grade Point Average Your GPA is the numerical system used by almost every

    E-Print Network [OSTI]

    Xi, Weimin

    hours of credit HIST 1301 for 3 semester hours of credit PSYC 2301 for 3 semester hours of credit MATH Hours X 3 = 9 Points PSYC 2301 D 3 Hours X 1 = 3 Points MATH 2413 B 4 Hours X 3 = 12 Points TOTAL SCH X 3 = 9 Points PSYC 2301 D 3 Hours X 1 = 3 Points MATH 2413 F 4 Hours X 0 = 0 Points TOTAL SCH: 16

  2. Revolving D-branes and Spontaneous Gauge Symmetry Breaking

    E-Print Network [OSTI]

    Satoshi Iso; Noriaki Kitazawa

    2015-10-07

    We propose a new mechanism of spontaneous gauge symmetry breaking in the world-volume theory of revolving D-branes around a fixed point of orbifolds. In this paper, we consider a simple model of the T6/Z3 orbifold on which we put D3-branes, D7-branes and their anti-branes. The configuration breaks supersymmetry, but the R-R tadpole cancellation conditions are satisfied. A set of three D3-branes at an orbifold fixed point can separate from the point, but when they move perpendicular to the anti-D7-branes put on the fixed point, they are forced to be pulled back due to an attractive interaction between the D3 and anti-D7 branes. In order to stabilize the separation of the D3-branes at nonzero distance, we consider revolution of the D3-branes around the fixed point. Then the gauge symmetry on D3-branes is spontaneously broken, and the rank of the gauge group is reduced. The distance can be set at our will by appropriately choosing the angular momentum of the revolving D3-branes, which should be determined by the initial condition of the cosmological evolution of D-brane configurations. The distance corresponds to the vacuum expectation values of brane moduli fields in the world-volume theory and, if it is written as M/Ms^2 in terms of the string scale Ms, the scale of gauge symmetry breaking is given by M. Angular momentum conservation of revolving D3-branes assures the stability of the scale M against Ms.

  3. 78.6%8 /209 81.3%3 /216 94.1%1 /218 100% Master's Course of Oral Health Science

    E-Print Network [OSTI]

    Yamamoto, Hirosuke

    22 22 40 F [] 37 30 12 120 #12;1 2 3 4 5 6 7 8:4510:15 10:3012:00 13:0014:30 14 D1 D2 D3 M1 M2 D1 D2 2 D3 e-learning #12;1 2 3 4 5 6 7 8:4510:15 10:3012

  4. Structural Analysis of a Highly Glycosylated and Unliganded gp120-Based Antigen Using Mass Spectrometry

    SciTech Connect (OSTI)

    L Wang; Y Qin; S Ilchenko; J Bohon; W Shi; M Cho; K Takamoto; M Chance

    2011-12-31

    Structural characterization of the HIV-1 envelope protein gp120 is very important for providing an understanding of the protein's immunogenicity and its binding to cell receptors. So far, the crystallographic structure of gp120 with an intact V3 loop (in the absence of a CD4 coreceptor or antibody) has not been determined. The third variable region (V3) of the gp120 is immunodominant and contains glycosylation signatures that are essential for coreceptor binding and entry of the virus into T-cells. In this study, we characterized the structure of the outer domain of gp120 with an intact V3 loop (gp120-OD8) purified from Drosophila S2 cells utilizing mass spectrometry-based approaches. We mapped the glycosylation sites and calculated the glycosylation occupancy of gp120-OD8; 11 sites from 15 glycosylation motifs were determined as having high-mannose or hybrid glycosylation structures. The specific glycan moieties of nine glycosylation sites from eight unique glycopeptides were determined by a combination of ECD and CID MS approaches. Hydroxyl radical-mediated protein footprinting coupled with mass spectrometry analysis was employed to provide detailed information about protein structure of gp120-OD8 by directly identifying accessible and hydroxyl radical-reactive side chain residues. Comparison of gp120-OD8 experimental footprinting data with a homology model derived from the ligated CD4-gp120-OD8 crystal structure revealed a flexible V3 loop structure in which the V3 tip may provide contacts with the rest of the protein while residues in the V3 base remain solvent accessible. In addition, the data illustrate interactions between specific sugar moieties and amino acid side chains potentially important to the gp120-OD8 structure.

  5. Effects of Respiratory Motion on Passively Scattered Proton Therapy Versus Intensity Modulated Photon Therapy for Stage III Lung Cancer: Are Proton Plans More Sensitive to Breathing Motion?

    SciTech Connect (OSTI)

    Matney, Jason; Park, Peter C. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (United States); Bluett, Jaques [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Chen, Yi Pei [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (United States); Liu, Wei; Court, Laurence E. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao, Zhongxing [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Li, Heng [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe, E-mail: rmohan@mdanderson.org [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-11-01

    Purpose: To quantify and compare the effects of respiratory motion on paired passively scattered proton therapy (PSPT) and intensity modulated photon therapy (IMRT) plans; and to establish the relationship between the magnitude of tumor motion and the respiratory-induced dose difference for both modalities. Methods and Materials: In a randomized clinical trial comparing PSPT and IMRT, radiation therapy plans have been designed according to common planning protocols. Four-dimensional (4D) dose was computed for PSPT and IMRT plans for a patient cohort with respiratory motion ranging from 3 to 17 mm. Image registration and dose accumulation were performed using grayscale-based deformable image registration algorithms. The dose–volume histogram (DVH) differences (4D-3D [3D = 3-dimensional]) were compared for PSPT and IMRT. Changes in 4D-3D dose were correlated to the magnitude of tumor respiratory motion. Results: The average 4D-3D dose to 95% of the internal target volume was close to zero, with 19 of 20 patients within 1% of prescribed dose for both modalities. The mean 4D-3D between the 2 modalities was not statistically significant (P<.05) for all dose–volume histogram indices (mean ± SD) except the lung V5 (PSPT: +1.1% ± 0.9%; IMRT: +0.4% ± 1.2%) and maximum cord dose (PSPT: +1.5 ± 2.9 Gy; IMRT: 0.0 ± 0.2 Gy). Changes in 4D-3D dose were correlated to tumor motion for only 2 indices: dose to 95% planning target volume, and heterogeneity index. Conclusions: With our current margin formalisms, target coverage was maintained in the presence of respiratory motion up to 17 mm for both PSPT and IMRT. Only 2 of 11 4D-3D indices (lung V5 and spinal cord maximum) were statistically distinguishable between PSPT and IMRT, contrary to the notion that proton therapy will be more susceptible to respiratory motion. Because of the lack of strong correlations with 4D-3D dose differences in PSPT and IMRT, the extent of tumor motion was not an adequate predictor of potential dosimetric error caused by breathing motion.

  6. Anomaly of Tensionless String in Light-cone Gauge

    E-Print Network [OSTI]

    Murase, Kenta

    2015-01-01

    The classical tensionless string theory has the spacetime conformal symmetry. We expect and require that the quantum tensionless string theory has it too. In the BRST quantization method, the theory has no spacetime conformal anomaly in two dimensions. On the other hand, in the light-cone gauge quantization without the mode expansion, the theory in $D>3$ has the spacetime conformal anomaly in the traceless part of $[\\mathcal{J}^{-I}, \\mathcal{K}^{J}]$ in some operator order. In this paper, we consider a tensionless closed bosonic string in the light-cone gauge and investigate the spacetime conformal anomaly in the theory with the mode expansion. The appearance of the spacetime conformal anomaly in the light-cone gauge is different between the case of $D>3$ and the case of $D=3$ and depends on the choice of the operator order. Therefore we must consider dangerous commutators in the spacetime conformal symmetry of $D>3$ and $D=3$ in each operator order separately. Specifically we calculate dangerous commutators...

  7. Quantum Moduli Space of the Cascading Sp(p+M) x Sp(p) Gauge Theory

    E-Print Network [OSTI]

    Fumikazu Koyama; Futoshi Yagi

    2006-12-27

    We extend the detailed analysis of the quantum moduli space of the cascading SU(p+M) x SU(p) gauge theory in the recent paper of Dymarsky, Klebanov, and Seiberg for the Sp(p+M) x Sp(p) cascading gauge theory, which lives on the world volume of p D3-branes and M fractional D3-branes at the tip of the orientifolded conifold. As in their paper, we also find in this case that the ratio of the deformation parameters of the quantum constraint on the different branches in the gauge theory can be reproduced by the ratio of the deformation parameters of the conifold with different numbers of mobile D3-branes.

  8. Saturation in diffractive deep inelastic eA scattering

    E-Print Network [OSTI]

    M. S. Kugeratski; V. P. Goncalves; F. S. Navarra

    2006-02-24

    In this paper we investigate the saturation physics in diffractive deep inelastic electron-ion scattering. We estimate the energy and nuclear dependence of the ratio $\\sigma^{diff}/\\sigma^{tot}$ and predict the $x_{\\pom}$ and $\\beta$ behavior of the nuclear diffractive structure function $F_{2,A}^{D(3)}(Q^2, \\beta, x_{IP})$. Moreover, we analyze the ratio $R^{diff}_{A1,A2}(Q^2, \\beta, x_{IP}) = F_{2,A1} ^{D(3)}/F_{2,A2} ^{D(3)}$, which probes the nuclear dependence of the structure of the Pomeron. We show that saturation physics predicts that approximately 37 % of the events observed at eRHIC should be diffractive.

  9. 34th St. 34th St. MichiganAve.MichiganAve.

    E-Print Network [OSTI]

    LdnalsIkcoRarteM A2 A3 A5 A6 B3 B4 B5 B6 C1 C2 D5 D1 D2 D3 Parking Lot Map Reserved Parking, No Parking Zones, and Vehicular & Pedestrian Obstructions All Permit and Visitor Parking Lots Parking Color Key Gold D5 A4 C5 B2 VLdnalsIkcoRarteM A2 A3 A5 A6 B3 B4 B5 B6 C1 C2 C5 D5 D1 D2 D3 Parking Lot Map Reserved Parking, No Parking Zones

  10. 34th St. 34th St. MichiganAve.MichiganAve.

    E-Print Network [OSTI]

    LdnalsIkcoRarteM A2 A3 A5 A6 B3 B4 B5 B6 C1 C2 D5 D1 D2 D3 Parking Lot Map Reserved Parking, No Parking Zones, and Vehicular & Pedestrian Obstructions All Permit and Visitor Parking Lots Parking Color Key Gold D5 A4 C5 B2 V­eniLneerG/ATC eniLdnalsIkcoRarteM A2 A3 A5 A6 B3 B4 B5 B6 C1 C2 C5 D5 D1 D2 D3 Parking Lot Map

  11. Gauge theories on hyperbolic spaces and dual wormhole instabilities

    SciTech Connect (OSTI)

    Buchel, Alex

    2004-09-15

    We study supergravity duals of strongly coupled four-dimensional gauge theories formulated on compact quotients of hyperbolic spaces. The resulting background geometries are represented by Euclidean wormholes, which complicate establishing the precise gauge theory/string theory correspondence dictionary. These backgrounds suffer from the nonperturbative instabilities arising from the D3D3-bar pair-production in the background four-form potential. We discuss conditions for suppressing this Schwingerlike instability. We find that Euclidean wormholes arising in this construction develop a naked singularity before they can be stabilized.

  12. Cyclone analysis for the abatement of grain sorghum emmissions in granaries 

    E-Print Network [OSTI]

    Avant, Robert V

    1976-01-01

    Incremental cones Dg Figure 7. Variable geometry cyclone ~ 28 Figure 8. 1D-1D cycione. Figure 9. 1D-2D cyc1one. 29 Figure 10. 1D-3D cyclone. 30 Figure 11. 2D-1D cyclone. Figure 12. 2D-2D cyclone. (Lapple cyclone) 32 Figure 13. 2D-3D cyclone... drop barrel by cone relationship 83 29 Pressure drop cone by barrel relationship 30. 1D-1D cyclone efficiencies 31. 1D-2D cyclone efficiencies 32. 2D-2D cyclone efficiencies 33. 2D-1D cyclone efficiencies 34. 3D-1D cyclone efficiencies 35. 3D-2D...

  13. Electric fields in a sheath near a metal-dielectric interface

    SciTech Connect (OSTI)

    Barnat, E.V.; Hebner, G.A. [Sandia National Laboratories, Albuquerque, New Mexico 87185-1423 (United States)

    2004-10-18

    Spatially resolved electric fields in the sheath region near a metal-dielectric junction were measured in a radio-frequency-driven argon plasma. The fields were determined by observing the Stark shifted transitions to the 13d[3/2]{sub 1} Rydberg state by laser-induced fluorescence-dip spectroscopy. Calibration of the Stark shifts for the 13d[3/2]{sub 1} Rydberg state were experimentally obtained in a separate apparatus. Maps of the electric fields illustrate that the structure of the sheath formed around the junction depended on both the surface material and on the configuration of the surface.

  14. Angular correlations of lepton pairs from vector boson and top quark decays in Monte Carlo simulations.

    E-Print Network [OSTI]

    Frixione, Stefano; Laenen, Eric; Motylinski, Patrick; Webber, Bryan R

    -space factorization d?3n+1?(P1 + P2; k1, . . . , k2n, r1, . . . , rn, x) = d?n+1?(P1 + P2; p1, . . . , pn, x) n ? i=1 d?3(pi; k2i?1, k2i, ri) dp2i 2pi , (2.13) with the three-body phase spaces on the r.h.s. accounting for the decays ti(pi) ?? Wi(qi) + bi(ri) ?? li(k2i...

  15. Recent Developments in Dual Lattice Algorithms

    E-Print Network [OSTI]

    J. Wade Cherrington

    2008-10-02

    We review recent progress in numerical simulations with dually transformed SU(2) LGT, starting with a discussion of explicit dual amplitudes and algorithms for SU(2) pure Yang Mills in D=3 and D=4. In the D=3 case, we discuss results that validate the dual algorithm against conventional simulations. We also review how a local, exact dynamical fermion algorithm can naturally be incorporated into the dual framework. We conclude with an outlook for this technique and a look at some of the current challenges we've encountered with this method, specifically critical slowing down and the sign problem.

  16. Aggie Band - 1971-1980 - 34 

    E-Print Network [OSTI]

    Unknown

    2006-11-22

    .) Acanthoparyphium spinulo- Martin, W. E.; and Bils, R. sum F., 1964 a, pis. figs. 1-11 excretory concretions; formation and fine structure Acanthopsolus oculatus Bauer, 0. N., [1949 b], I63 (Levinsen) Lena river [Myoxocephalus sp.] Acanthopsolus oculatus.... Allocreadium Looss, I9OO Roitman, V. ?., I963 d, 3?3 Allocreadiidae Stossich, I9O3 Allocreadium sp. ?Phoxinus czekanowskii] P. percnurus] Bauer, 0. N., [1949 a], II3-114, fig. 3 all from Yenisei river Roitman, V. ?., I963 d, 3II Allocreadium baueri Spassky...

  17. Electromechanical Limits of Polymersomes

    E-Print Network [OSTI]

    H. Aranda-Espinoza; H. Bermudez; F. S. Bates; D. Discher

    2001-07-02

    Self-assembled membranes of amphiphilic diblock copolymers enable comparisons of cohesiveness with lipid membranes over the range of hydrophobic thicknesses d=3-15 nm. At zero mechanical tension the breakdown potential V_c for polymersomes with d=15 nm is 9 V compared to 1 V for liposomes with d=3 nm. Nonetheless, electromechanical stresses at breakdown universally exhibit a square dependence on V_c, and membrane capacitance shows the expected strong d-dependence, conforming to simple thermodynamic models. The viscous nature of the diblock membranes is apparent in the protracted post-poration dynamics.

  18. Multipolar expansion of the electrostatic interaction between charged colloids at interfaces

    E-Print Network [OSTI]

    A. Dominguez; D. Frydel; M. Oettel

    2007-10-23

    The general form of the electrostatic potential around an arbitrarily charged colloid at an interface between a dielectric and a screening phase (such as air and water, respectively) is analyzed in terms of a multipole expansion. The leading term is isotropic in the interfacial plane and varies with $d^{-3}$ where $d$ is the in--plane distance from the colloid. The electrostatic interaction potential between two arbitrarily charged colloids is likewise isotropic and $\\propto d^{-3}$, corresponding to the dipole--dipole interaction first found for point charges at water interfaces. Anisotropic interaction terms arise only for higher powers $d^{-n}$ with $n \\ge 4$.

  19. First Observations of Nonhydrodynamic Mix at the Fuel-Shell Interface in Shock-Driven Inertial Confinement Implosions

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Rinderknecht, H. G.; Sio, H.; Li, C. K.; Zylstra, A. B.; Rosenberg, M. J.; Amendt, P.; Delettrez, J.; Bellei, C.; Frenje, J. A.; Gatu Johnson, M.; et al

    2014-04-01

    A strong nonhydrodynamic mechanism generating atomic fuel-shell mix has been observed in strongly shocked inertial confinement fusion implosions of thin deuterated-plastic shells filled with 3He gas. These implosions were found to produce D3He-proton shock yields comparable to implosions of identical shells filled with a hydroequivalent 50:50 D3He gas mixture. Standard hydrodynamic mixing cannot explain this observation, as hydrodynamic modeling including mix predicts a yield an order of magnitude lower than was observed. Instead, these results can be attributed to ion diffusive mix at the fuel-shell interface.

  20. Natural CD8{sup +}25{sup +} regulatory T cell-secreted exosomes capable of suppressing cytotoxic T lymphocyte-mediated immunity against B16 melanoma

    SciTech Connect (OSTI)

    Xie, Yufeng; Zhang, Xueshu; Zhao, Tuo; Li, Wei; Xiang, Jim, E-mail: jim.xiang@saskcancer.ca

    2013-08-16

    Highlights: •CD8{sup +}25{sup +} regulatory T cells secrete tolerogenic exosomes. •CD8{sup +}25{sup +} regulatory T cell-derived exosomes exhibit immunosuppressive effect. •CD8{sup +}25{sup +} regulatory T cell-derived exosomes inhibit antitumor immunity. -- Abstract: Natural CD4{sup +}25{sup +} and CD8{sup +}25{sup +} regulatory T (Tr) cells have been shown to inhibit autoimmune diseases. Immune cells secrete exosomes (EXOs), which are crucial for immune regulation. However, immunomodulatory effect of natural Tr cell-secreted EXOs is unknown. In this study, we purified natural CD8{sup +}25{sup +} Tr cells from C57BL/6 mouse naive CD8{sup +} T cells, and in vitro amplified them with CD3/CD28 beads. EXOs (EXO{sub Tr}) were purified from Tr cell’s culture supernatants by differential ultracentrifugation and analyzed by electron microscopy, Western blot and flow cytometry. Our data showed that EXO{sub Tr} had a “saucer” or round shape with 50–100 nm in diameter, contained EXO-associated markers LAMP-1 and CD9, and expressed natural Tr cell markers CD25 and GITR. To assess immunomodulatory effect, we i.v. immunized C57BL/6 mice with ovalbumin (OVA)-pulsed DCs (DC{sub OVA}) plus Tr cells or EXO{sub Tr}, and then assessed OVA-specific CD8{sup +} T cell responses using PE-H-2K{sup b}/OVA tetramer and FITC-anti-CD8 antibody staining by flow cytometry and antitumor immunity in immunized mice with challenge of OVA-expressing BL6–10{sub OVA} melanoma cells. We demonstrated that DC{sub OVA}-stimulated CD8{sup +} T cell responses and protective antitumor immunity significantly dropped from 2.52% to 1.08% and 1.81% (p < 0.05), and from 8/8 to 2/8 and 5/8 mice DC{sub OVA} (p < 0.05) in immunized mice with co-injection of Tr cells and EXO{sub Tr}, respectively. Our results indicate that natural CD8{sup +}25{sup +} Tr cell-released EXOs, alike CD8{sup +}25{sup +} Tr cells, can inhibit CD8{sup +} T cell responses and antitumor immunity. Therefore, EXOs derived from natural CD4{sup +}25{sup +} and CD8{sup +}25{sup +} Tr cells may become an alternative for immunotherapy of autoimmune diseases.

  1. Name Num. Grid 259 Wadell St 0757 B -1

    E-Print Network [OSTI]

    Arnold, Jonathan

    , B - 4 Food Processing Lab 1022 C - 3 Food Science Building 1020 D - 3 Forestry Resources 1 1040 C - 4 Forestry Resources 2 1140 C - 4 Forestry Resources 3 1044 C - 4 Forestry Resources 4 1046 C - 4 0043 C - 1 Hodgson Oil Building 0019 D - 1 Hoke Smith Annex 1042 B - 4 Holmes/Hunter Academic Building

  2. Deadline-Aware Datacenter TCP (D2 Balajee Vamanan

    E-Print Network [OSTI]

    Cortes, Corinna

    Deadline-Aware Datacenter TCP (D2 TCP) Balajee Vamanan Purdue University bvamanan@ecn.purdue.edu ABSTRACT An important class of datacenter applications, called Online Data- Intensive (OLDI) applications on datacenter network protocols is either deadline-agnostic (DCTCP) or is deadline-aware (D3 ) but suffers under

  3. Wednesday, August 21, 2013 Biological Sciences Learning Center | Room 115

    E-Print Network [OSTI]

    Sherman, S. Murray

    Patients at Increased Risk of Hospitalization Mentor: David Meltzer, MD, PhD 3:30pm Amrita Mukhopadhyay Guided L5/S1 Placement of Labor Epidurals Does Not Improve Dermatomal Blockade in Parturients Mentor, PhD 10:20am BREAK 10:40am Craig Brown Risk Factors Predicting Progression from Barrett's Esophagus

  4. Demo time! www.nationaleatlas.nl

    E-Print Network [OSTI]

    ? #12;Brief history of the Dutch National Atlas after 1998 government involvement and funding ended Platform - uses D3 library #12;Architecture: middleware ATLAS utility services & basedata #12;Architecture;Conclusions the test bed shows: that a (National) Atlas as an integral part of a (National) SDI is feasible

  5. Nordic Journal of Computing TOWARDS FULLY-FLEDGED REVERSE

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    .g. from standard libraries. The situation is particularly difficult when one needs to combine two or more is perhaps the most suitable language for that purpose because of its flexible inheritance principles and Features -- inheritance; D.3.2 [Programming Languages]: Language Classifications -- object

  6. A Practical Type Analysis for Verification of Modular Prolog Programs

    E-Print Network [OSTI]

    Puebla, Germán

    in the libraries. We claim that, for the purpose of verifying type signatures given in the form of asser- tions of reanalysis performed, especially for library modules. Borrowing some ideas from polymorphic type systems, we, Diagnostics, Symbolic execution; D.3.2 [Software Engineering]: Language Classifications--Constraint and logic

  7. Domain-Driven Data Mining: Challenges and Prospects

    E-Print Network [OSTI]

    Cao, Longbing

    in real- world smart decision making. To this end, domain-driven data mining (D3 M) has been proposed, which is supposed to enable smart business intelligence for smart decisions in production. If we by business people for seamless decision making. To bridge the gap and enhance real-world problem- solving

  8. NATIONAL RADIO ASTRONOMY OBSERVATORY GREEN BANK, WEST VIRGINIA

    E-Print Network [OSTI]

    Groppi, Christopher

    TU VLA GB Library ER Library Library Downtown VIA Library R. Lacasse IR Library Library Mountain P to weather information, 16 bits of digital input and output were provided. In order to provide isolation Ch 7 64 Digital Output, 16 Bits DO Alarm, output a 1 to close a contact D1-D3 Spare output contact

  9. Proton core imaging of the nuclear burn in inertial confinement fusion implosions

    E-Print Network [OSTI]

    Proton core imaging of the nuclear burn in inertial confinement fusion implosions J. L. De; published online 7 April 2006 A proton emission imaging system has been developed and used extensively the penetrating 14.7 MeV protons produced from D 3 He fusion reactions to produce emission images of the nuclear

  10. He-proton emission imaging for inertial-confinement-fusion experiments (invited)

    E-Print Network [OSTI]

    D3 He-proton emission imaging for inertial-confinement-fusion experiments (invited) F. H. Séguin, Livermore, California 94550 (Presented on 19 April 2004; published 5 October 2004) Proton emission imaging cameras, in combination with proton spectrometers and a proton temporal diagnostic, provide a great deal

  11. Working Group 4 April 25 -30 2000

    E-Print Network [OSTI]

    DIS2000 Working Group 4 April 25 - 30 2000 Liverpool, UK Di#11;ractive D #3;#6; (2010) Production Selection #15; Results from ZEUS and H1 #15; Conclusions #12; DIS2000 | Working Group 4 Jo Cole Why measure states, eg. J= #15; Study of charm provides test of under- lying dynamics of di#11;raction April 2000 2

  12. Self-organized mode-locking effect in superconductor/ferromagnet hybrids J. Van de Vondel,1 A. V. Silhanek,1 V. Metlushko,2 P. Vavassori,3,4 B. Ilic,5 and V. V. Moshchalkov1

    E-Print Network [OSTI]

    Metlushko, Vitali

    between a vortex line and a finite-size permanent magnet is given by3 Up R = - dot m · Bv R - r d3 r, 1 of the vortex line, m is the magnetic moment of the ferromagnetic dot and Bv is the field generated and Magnetism Group, INPAC-Institute for Nanoscale Physics and Chemistry, K. U. Leuven, Celestijnenlaan 200D, B

  13. MHD Simulations of the Parker Model of Solar Coronal Heating

    E-Print Network [OSTI]

    Ng, Chung-Sang

    MHD Simulations of the Parker Model of Solar Coronal Heating Chung-Sang Ng Geophysical Institute, University of Alaska Fairbanks Collaborators: Amitava Bhattacharjee, Liwei Lin, Tim Dennis Funding.alaska.edu/~chungsangng/ · 2D/3D BGK modes (with/without magnetic field) · MHD turbulence (theory/simulations/solar wind

  14. Limbic System Page 1 of 10 Srdjan D. Antic, M.D. Limbic system Emotional Experience

    E-Print Network [OSTI]

    Oliver, Douglas L.

    function. NMDA-dependent long-term potentiation is a cellular mechanism responsible for fear conditioning.M. is the most studied patient with Urbach-Wiethe disease. After a battery of tests, which included spiders Srdjan D. Antic, M.D. 3 as well as an appetitive (positive) conditioning. Individuals with larger

  15. A strongly coupled anyon material

    E-Print Network [OSTI]

    Daniel K. Brattan

    2014-12-03

    We use alternative quantisation of the D3-D5 system to explore properties of a strongly coupled anyon material at finite density and temperature. We study the transport properties of the material and find both diffusion and massive holographic zero sound modes. By studying the anyon number conductivity we also find evidence for the anyonic analogue of the metal-insulator transition.

  16. The Essentials of Software Testing 1 Copyright Data Kinetics Ltd. STP 2.1 11/98

    E-Print Network [OSTI]

    Boetticher, Gary D.

    The Essentials of Software Testing 1 Copyright Data Kinetics Ltd. STP 2.1 ­ 11/98 Exhibit D-3 check-points in long tests. 10. TEST DELIVERABLES What, besides software, will be delivered? Test report Test software 11. TESTING TASKS Functional tasks (e.g., equipment set up) Administrative tasks 12

  17. Couplings between Chern-Simons gravities and 2p-branes

    SciTech Connect (OSTI)

    Miskovic, Olivera; Zanelli, Jorge

    2009-08-15

    The interaction between Chern-Simons (CS) theories and localized external sources (2p-branes) is analyzed. This interaction generalizes the minimal coupling between a point charge (0-brane) and a gauge connection. The external currents that define the 2p branes are covariantly constant (D-2p-1)-forms coupled to (2p-1) CS forms. The general expression for the sources--charged with respect to the corresponding gauge algebra--is presented, focusing on two special cases: 0-branes and (D-3)-branes. In any dimension, 0-branes are constructed as topological defects produced by a surface deficit of (D-2)-sphere in anti-de Sitter space, and they are not constant curvature spaces for D>3. They correspond to dimensionally continued black holes with negative mass. On the other hand, in the case of CS (super) gravities, the (D-3)-branes are naked conical singularities (topological defects) obtained by identification of points with a Killing vector. In 2+1 dimensions, extremal spinning branes of this type are Bogomol'nyi-Prasad-Sommerfield states. Stable (D-3)-branes are shown to exist also in higher dimensions, as well. Classical field equations are also discussed, and in the presence of sources there is a large number of inequivalent and disconnected sectors in solution space.

  18. Pluggable Abstract Domains for Analyzing Embedded Software Nathan Cooprider John Regehr

    E-Print Network [OSTI]

    Regehr, John

    of cXprop, an analysis and trans- formation tool for C that implements "conditional X propagation size reduction of 8.2% through RAM compression. Categories and Subject Descriptors D.3.4 [Programming functions conforming to an abstract domain interface that we developed. cXprop can operate in three modes

  19. The Accreting Black Hole Swift J1753.5-0127 from Radio to Hard X-Ray

    E-Print Network [OSTI]

    Tomsick, John A; Kolehmainen, Mari; Miller-Jones, James; Fuerst, Felix; Yamaoka, Kazutaka; Akitaya, Hiroshi; Corbel, Stephane; Coriat, Mickael; Done, Chris; Gandhi, Poshak; Harrison, Fiona A; Huang, Kuiyun; Kaaret, Philip; Kalemci, Emrah; Kanda, Yuka; Migliari, Simone; Miller, Jon M; Moritani, Yuki; Stern, Daniel; Uemura, Makoto; Urata, Yuji

    2015-01-01

    (abridged) We report on multi-wavelength measurements of Swift J1753.5-0127 in the hard state at L=2.7e36 erg/s (assuming d=3 kpc) in 2014. The radio emission is optically thick synchrotron, presumably from a compact jet. We take advantage of the low extinction and model the near-IR to UV emission with a multi-temperature disk model. Assuming a BH mass of M_BH=5 Msun and a system inclination of 40 deg, the fits imply an inner radius for the disk of Rin/Rg>212 d_3 (5Msun/M_BH). The outer radius is R_out/R_g=90,000 d_3 (5Msun/M_BH), which corresponds to 6.6e10 d_3 cm, consistent with the expected size of the disk. The 0.5-240 keV spectrum measured by Swift/XRT, Suzaku, and NuSTAR is relatively well characterized by a power-law with a photon index of Gamma=1.722+/-0.003, but a significant improvement is seen when a second continuum component is added. Reflection is a possibility, but no iron line is detected, implying a low iron abundance. We are able to fit the entire SED with a multi-temperature disk component...

  20. Thermo-mechanical approach to validation of deep crustal and lithospheric structures inferred from multidisciplinary data

    E-Print Network [OSTI]

    Podladchikov, Yuri

    -sections, gravity profiles, and partly magnetic, geodetic, thermal and stratigraphy data. Seismic data on bulk- gical and geophysical 2D/3D data sources (Ledru et al., 1997). Seismic data are a major source-unique. Forthis reason, potential field data (gravity, magnetics) are used to constrain and complete seismically

  1. Preguntas muestra del examen de admisin al posgrado en Ciencias de la Computacin

    E-Print Network [OSTI]

    -=-=-= xxx d. 3,2,1 321 === xxx e. 0,2,1 321 =-== xxx 2. Elija la expresión equivalente a CBA . a. CBA b. CBA c. CBA d. CBA e. CBA 3. ¿Cuántas diagonales se pueden trazar en un polígono de n lados? a. 2

  2. INGENIRUDDANNELSER P AARHUS UNIVERSITET, SCIENCE & TECHNOLOGY

    E-Print Network [OSTI]

    Bataillon, Thomas

    ENGELSK2 INGENIØRUDDANNELSER PÅ AARHUS UNIVERSITET, SCIENCE & TECHNOLOGY FORSKER (Ph.d.) (3 år Design Engineer (Elektronik) - Herning Business Development Engineer - Herning 4½ år Global Management and Manufacturing - Herning JOBJOB JOB JOB CIVILINGENIØR (+2 år) Biomedicinsk teknologi Byggeri Kemi og bioteknologi

  3. CX-001422: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    A 3D-3C Reflection Seismic Survey and Data Integration to Identify the Seismic Response of Fractures and Permeable Zones Over a Known Geothermal Resource: Soda lake, Churchill County, NevadaCX(s) Applied: B3.1, A9Date: 03/29/2010Location(s): Soda Lake, NevadaOffice(s): Energy Efficiency and Renewable Energy, Golden Field Office

  4. Tactile Switch (SMD) B3FS1138 Tactile Switch (SMD)

    E-Print Network [OSTI]

    Berns, Hans-Gerd

    Tactile Switch (SMD) B3FS1138 Tactile Switch (SMD) B3FS Surface-mounting Switches Ideal for High mechanism that ensures sharp switching operations D 3 actuator heights for design flexibility D Ro,000 pieces. For the packing style, refer to Key Switch Packing under Precautions section. Important Note

  5. College of Physical and Mathematical Sciences Brigham Young University

    E-Print Network [OSTI]

    Hart, Gus

    Expectations Document 4C. Chair's Expectations 4D. 3rd Year Review Letter (Required for sixth-year review) 4E FOR CONTINUING FACULTY STATUS AND ADVANCEMENT IN RANK Name: BYU ID: Year Appointed: Current Rank: Year Received: Department: College: Physical and Mathematical Sciences Highest Degree: Year: Institution: For advancement

  6. College of Physical and Mathematical Sciences Brigham Young University

    E-Print Network [OSTI]

    Hart, Gus

    . Department Expectations Document 4C. Chair's Expectations 4D. 3rd Year Review Letter (Required for sixth-year AND ADVANCEMENT IN RANK Name: BYU ID: Year Appointed: Current Rank: Year Received: Department: College: Highest Degree: Year: Institution: ___ For advancement to the rank of : ___ Initial Review for Candidacy

  7. ESnet Visualization Widgets

    SciTech Connect (OSTI)

    Gopal Vaswani, Jon Dugan

    2012-07-01

    The ESnet Visualization widgets are various data visualization widgets for use in web browsers to aid in the visualization of computer networks. In particular the widgets are targetted at displaying timeseries and topology data. They were developed for use in the MyESnet portal but are general enough to be used other places. The widgets are built using the d3.js library.

  8. Engineering Formal Metatheory Brian Aydemir

    E-Print Network [OSTI]

    Pollack, Randy

    @cis.upenn.edu Arthur Chargu´eraud INRIA arthur.chargueraud@inria.fr Benjamin C. Pierce University of Pennsylvania and little infras- tructure within the proof assistant. We have carried out several large developments, California, USA. Copyright c 2008 ACM 978-1-59593-689-9/08/0001...$5.00 rem proving; D.3.1 [Programming

  9. Engineering Formal Metatheory Brian Aydemir

    E-Print Network [OSTI]

    Ahmed, Amal

    @cis.upenn.edu Arthur Chargu´eraud INRIA arthur.chargueraud@inria.fr Benjamin C. Pierce University of Pennsylvania and little infras- tructure within the proof assistant. We have carried out several large developments. The definitive version will appear in the proceedings of POPL 2008. rem proving; D.3.1 [Programming Languages

  10. Modeling of reflected and scattered light intensity of ordered mesoporous layers of silica

    E-Print Network [OSTI]

    Boyer, Edmond

    a periodic lattice, the structure factor modulates the optical properties and the form factor that describes 1. Introduction Mesoporous materials are artificial materials with potential optical applications [1 for mesoporous layer- SiO2 and 34 for SiO2­Si interfaces respectively. Then, let us write q24 ¼ q23 þ q34e2ik3d3

  11. LOW TEMPERATURE OPTICAL STUDY OF MANGANOUS CHLORIDE M. REGIS and Y. FARGE

    E-Print Network [OSTI]

    Boyer, Edmond

    that, in a lot of transparent magnetic materials, the behaviour of the optical spectrum is related of metal atoms are separated by two layers of chlorine atoms. The crystal field D3d on the manganese ions627 LOW TEMPERATURE OPTICAL STUDY OF MANGANOUS CHLORIDE M. REGIS and Y. FARGE Laboratoire de

  12. CLNS00/1710 STRING WEBS AND THE DECAY OF

    E-Print Network [OSTI]

    CLNS­00/1710 STRING WEBS AND THE DECAY OF SUPERSYMMETRIC PARTICLES PHILIP C. ARGYRES and K. NARAYAN is a generalization of the ``string web'' picture of these states found in string constructions of certain theories coincides with the ``string web'' picture of BPS states developed in the context of the D3­brane

  13. 16th Int Symp on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 912 July, 2012

    E-Print Network [OSTI]

    Garbe, Christoph S.

    16th Int Symp on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 9­12 July on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 9­12 July, 2012 In this equation, (gx, gy, 2012 Plenoptic Particle Streak Velocimetry (pPSV): 3D3C fluid flow measurement from light fields

  14. K. Czarnecki et al. (Eds.): MoDELS 2008, LNCS 5301, pp. 264279, 2008. Springer-Verlag Berlin Heidelberg 2008

    E-Print Network [OSTI]

    van Schyndel, Ron

    UML, X3D, 3D Software Visualization, VRML. 1 Introduction Computers in current day software development houses are now capable of rendering quality real time 3D visualisations. In the past, 3D into the overall benefit of completing common and critical software engineer- ing tasks with UML extended using 3D

  15. EMCF08 Math 1432, 13209 The answer sheet for this assignment can be found by logging into CourseWare at

    E-Print Network [OSTI]

    Glowinski, Roland

    . 0 d. 3 e. None of these. 3. dx x2 29 1 a. Cx 3 2 arctan 23 1 b. Cx 3 2 arctan 6 1 c. Cx 3 2 arctan 2 1 d. Cx 3 2 arctan 2 1 e. None of these. #12;4. 4 1 2 x dx x a. 2ln2

  16. !"#$"%i"g )#* +*%#$"i%$, $"-F/$%)0/* 1/23*/)i*4 25 6$"2%27324i)*4 84i"g 9$/:2" 6$"2)0:*4

    E-Print Network [OSTI]

    Thouless, Michael

    for energy storage D1E, high-k dielectrics D2E, light-emitting diodes D3E, actuators D4E, sensors D5E, among, silicon, metals, among others) in oppositely-charged solutions to deposit various nanomaterials one

  17. ONETEP: linear-scaling density-functional theory with plane-waves

    E-Print Network [OSTI]

    Haynes, Peter

    overview of the methodology implemented in onetep (Order-N Electronic Total Energy Package), a parallel(r) = jkjk(r) , (1) n(r) = cell j 1BZ d3k (2)3 fjk |jk(r)|2 , (2) where j, k and label the band index, k

  18. What we've learned so far about the Stability of Plasma

    E-Print Network [OSTI]

    of Technology About PSFC Research People Education News & Even The Plasma Science & Fusion Center (PSFC Rick Phil Joe #12;Dipole Fusion Concept Testing a New Approach to Fusion and Laboratory Plasma. Nucl. Fus. 2002 #12;Dipole Fusion Concept · Advanced fusion fuel... D-D (3He) with active triton

  19. WENDELSTEIN 7-X Verification of the CAS3D-perturbed equilibrium code

    E-Print Network [OSTI]

    Hudson, Stuart

    .H. Boozer2 1 PPPL, Princeton NJ 08543, 2 Columbia University, New York NY 10027 USA http. Phys. Commun. 43 , 157 (1986). · Ideal MHD energy principle ·plasma equilibrium and stability: minimize s 2 + p( · )2 - A(s )2 d3 r Summary In the context of perturbed equilibria an alternative method

  20. Theoretical study of cyclone design 

    E-Print Network [OSTI]

    Wang, Lingjuan

    2005-08-29

    velocities, which are 16 m/s (3200 ft/min) for 1D3D cyclones and 15 m/s (3000 ft/min) for 2D2D cyclones, should be determined based on standard air density. It is important to consider the air density effect on cyclone performance in the design of cyclone...

  1. Cloud County Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    21 ENGL 102 Critical Reading and Writing 3 CM 102 English Composition 2 3 GE21 Choose One: Core CM: Design Think & Make 2 3 AR 171 Design 2 3-D 3 Studio Requirements/Electives (15 hours) Photo Media elective (at least one) 3 AR 118 Photography 3 AR Photography 2 3 AR 129 Intro Digital Photo 3 Plus 12

  2. Anomalous expansion and negative specific heat in quasi-2D plasmas

    E-Print Network [OSTI]

    Lim, Chjan C.

    Anomalous expansion and negative specific heat in quasi-2D plasmas Timothy D. Andersen and Chjan C. Lim May 23, 2010 #12;Magnetic Nuclear Fusion Magnetic nuclear fusion is one of the most promising confining the plasma. #12;Magnetic Nuclear Fusion continued 2 1D +3 1 T 4 2 He +1 0 n + 17.6MeV. (1) Plasma

  3. Synthesis of triglyceride by the intestinal mucosa 

    E-Print Network [OSTI]

    Buell, George Christopher

    1958-01-01

    c3r pfdD3uc.2 aucR C3rf 2so2py-r- c3uc ar- tpf2resp -srP osc cu6r Duec .o c3r erPfoc3rP.P sa aucP .o c3r .ocrPc.orR Sucre .c 7uP P3s7o if Tr.Pre rc up ?p?? c3uc -.3f-esnfu2rcsor rPcreP duf ir c3r Der2yePse sa c3r tpf2resp sa c3r ce.tpf2re.-rP er...rcsor D3sPD3ucr uo- SU? Utpf2resD3sPD3ucrR Sucre rb.-ro2r c3uc c3r Der2yePse duf p.r .o c3.P drcuisp.2 Duc3 7uP Desb.-r- if c3r 7se6 sa +seoiret uo- le.2re ?Yq? 18?R C3rf 7rer uipr cs rPcre.af SUUtpf2resD3sPD3ucr 7.c3 1s8 rPcreP sa psot 23u.o auccf u...

  4. J.M. Butler VA DFS 2007 Training Workshop March 14, 2007 http://www.cstl.nist.gov/biotech/strbase/training.htm 1

    E-Print Network [OSTI]

    E D18S51 D21S11 TH01 D3S1358 Figure 14.9, J.M. Butler (2005) Forensic DNA Typing, 2nd Edition © 2005 EElectrophoresis (and microchip CE) Fundamentals Dr. John M. Butler National Institute of Standards and Technology for Forensic DNA Typing · Idea · Demonstration of feasibility · Research and development · Commercialization

  5. Gas Chromatographic Separation of Isotopic Molecules Using a Cavitand-Impregnated Ionic

    E-Print Network [OSTI]

    Reid, Scott A.

    of isotopic com- pounds including aromatic hydrocarbons (mixture of chlorobenzene-h5 and chlorobenzene-d5, mixture of 1,2- dichlorobenzene-h4 and 1,2-dichlorobenzene-d4), al- cohols (methanol from its corresponding methanol-d, d3, d4), ether, pyridine, and acetonitrile. The results also show that by modifying

  6. TECHNICAL NOTES Drought Storage Allocation Rules for Surface

    E-Print Network [OSTI]

    Pasternack, Gregory B.

    TECHNICAL NOTES Drought Storage Allocation Rules for Surface Reservoir Systems Jay R. Lund1 Abstract: This technical note develops a simple drought storage allocation rule to minimize evaporative as a function of storage in the following equation: D = d 3S ab 1/3 2 Marginal Losses In developing an operating

  7. The Gardens Inn at Carnall Hall

    E-Print Network [OSTI]

    Capogna, Luca

    /Bio-Chemistry Research (C-4) CHEM Chemistry (C-4) CIOS Chi Omega Sorority (B-3) COGT Chi Omega Greek Theater (C-3) CRED (D-3) AOPS Alpha Omicron Pi Sorority (B-5) ARKU Arkansas Union (C-3) ARMY Army ROTC (B-4) KASF Kappa

  8. Cellular CSK resembles natural and synthetic materials

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    Theory Pinned-pinned, three-point bending Es is modulus of elasticity for beam (F-actin GPa) d 3 48 s F l E ISession 15 #12;2 Cellular CSK resembles natural and synthetic materials Felt Paper Cotton NASA r r #12;6 (a/k/a Second Moment of Area) Geometric resistance of a beam to bending 2 2

  9. JSetL: Declarative Programming in Java with Sets G. Rossi, E. Poleo

    E-Print Network [OSTI]

    Rossi, Gianfranco

    Descriptors D.3.3 [Programming Languages]: Language Constructs and Features|Constraints; D.1.5, D.1.6 [Programming Techniques]: Object-oriented Programming, Logic Pro- gramming General Terms Languages, Algorithms logic programming languages (e.g., Oz [13])). As a matter of fact, constraints provide a powerful tool

  10. Practical Extensions in Agent Programming Languages Mehdi Dastani

    E-Print Network [OSTI]

    Dastani, Mehdi

    Practical Extensions in Agent Programming Languages Mehdi Dastani Utrecht University to improve the practi- cal application of existing BDI-based agent-oriented programming languages that have and declarative programming languages. Categories and Subject Descriptors D.3.3 [Programming Languages]: Language

  11. ALGORITHM 572 Solution of the Helmholtz Equation for the

    E-Print Network [OSTI]

    O'Leary, Dianne P.

    -Dimensional Regions [D3] DIANNE P. O'LEARY University of Maryland and OLOF WlDLUND New York University Key/or specific permission. The work of D. P O'Leary was supported by National Scmnce Foundation Grant MCS 76 and Development Agency under Contract EY-76-C-02-3077. Authors' addresses: D. P O'Leary, Computer Science

  12. Journal of Steroid Biochemistry & Molecular Biology 104 (2007) 269273 Aberrant nest building and prolactin secretion in

    E-Print Network [OSTI]

    Kalueff, Allan V.

    2007-01-01

    , Medical School, University of Tampere, Tampere 33014, Finland b Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland c Department of Clinical Chemistry, Tampere University Hospital, Tampere, Finland Abstract 1 ,25(OH)2D3, the hormonal form of vitamin D, is a neuroactive seco

  13. Finance Committee Terms of Reference, Membership and Operating Procedures

    E-Print Network [OSTI]

    Botea, Adi

    95/2012 Finance Committee ­ Terms of Reference, Membership and Operating Procedures Principles 1 on, or pose any reasonable risk to, the University's finances and operations" section 18(4)(d). 3. Council has established a Finance Committee as a committee of Council. 4. The broad purpose of the Finance

  14. Allen Hall....................................ALLEN D2 Alumni Hall..................................ALUM E2

    E-Print Network [OSTI]

    Kalisz, Susan

    F1 · Old Engineering Hall ....................OEH D2 Oxford Bldg.(3501 Forbes Ave.) OXFRD C4.............................BELLH G2 Bellefield Presbyterian Church...PRES D3 Bellefield Towers.........................BELLT F1 ....................CHILD C3 Clapp Hall..................................CLAPP F1 Community of Reconciliation Bldg. ..CR F1

  15. NIK 2005 / How to transform UML neg into a useful construct Ragnhild Kobro Runde UML neg nyttig eller ubrukelig?

    E-Print Network [OSTI]

    Runde, Ragnhild Kobro

    positive for neg d? 1. Alle som ikke er negative. 2. De negative tracene til d. 3. Ingen tracer. 4. Den S T A I R S SS TT AA II RR SS Alternativ 3 · neg d har ingen positive tracer: [[ neg d

  16. Wt l l \\l \\l l \\l l \\\\ \\\\ \\\\ \\\\ \\\\ \\\\ \\\\ \\\\ \\\\ \\\\, t \\\\ \\\\ \\\\ \\\\ \\\\ \\\\ \\l,

    E-Print Network [OSTI]

    A) e2y_%ezy B) (ln y)e*(l”y)2/2 C) ell—i623, D) 3/592” E) e?ezy. 5. An insurer estimates that Smith's time until death is uniformly distributed on the interval [0, 5].

  17. Data Acquisition Interpretation

    E-Print Network [OSTI]

    Oldenburg, Douglas W.

    Data Acquisition Inversion Interpretation Discussion Virgin River DCIP Report Justin Granek1 1 Report #12;Data Acquisition Inversion Interpretation Discussion Outline 1 Data Acquisition Location Survey Specications 2 Inversion Data Errors DCIP2D DCIP3D 3 Interpretation Correlations Snowbird Tectonic

  18. Name Num. Grid 259 Wadell St 0757 B -1

    E-Print Network [OSTI]

    Rasheed, Khaled

    - 2 Central Food Storage 2122 E - 6 Central Heating Plant 1 1620 C - 3 Central Heating Plant 2 1618 C Hall 0044 C - 1 District Energy Plant #1 0741 B - 2 District Energy Plant #2 1617 C - 3, D - 3 Drawing

  19. Role of Advanced-Fuel and Innovative Concept Fusion in the

    E-Print Network [OSTI]

    Fusion Technology Institute Main Thesis of This Talk: D-3He Fuel Could Lower R&D Costs · Engineering RRole of Advanced-Fuel and Innovative Concept Fusion in the Nuclear Renaissance John F. Santarius and Innovative Fusion Concepts? · Fusion development requires physics, engineering, safety, and environmental

  20. The Normal Modes of the Earth Lapo Boschi (lapo@erdw.ethz.ch)

    E-Print Network [OSTI]

    Boschi, Lapo

    ) is given by Newton's law of gravitation, ¨u(r, t) = V r - r |r - r|3 G(r )d3 r , (1) with G denoting Newton, with associated eigenfrequencies: the normal modes (free oscillations) of the Earth. Self-Gravitation to the gravity field caused by the Earth's deformation u(r, t) itself ("self-gravitation"). Those terms, how

  1. Nuclear magnetic octupole moment and the hyperfine structure of the 5D32,52 states A. Derevianko,1,2

    E-Print Network [OSTI]

    Blinov, Boris

    Nuclear magnetic octupole moment and the hyperfine structure of the 5D3Õ2,5Õ2 states of the Ba+ ion nuclear magnetic moments is presented. The relevant electronic matrix elements are computed relatively unexplored. While octupole moments may be approximated using the nuclear-shell model 1

  2. Recent Flare Studies at NJIT Outline of Studies

    E-Print Network [OSTI]

    continuum brightening (white-light flares) Black-light solar flares (BLFs; Henoux et al. 1990): electron flares. - Solar limb in D3, showing a narrow, bright band above the photosphere between 1000 and 2500 km3/28/2014 1 Recent Flare Studies at NJIT Lecture 10 Outline of Studies Black Light Flares Moreton

  3. Journal of Statistical Physics, Vol. 65, Nos. 1/2, 1991 Upper Bound on the Condensate in the

    E-Print Network [OSTI]

    Tóth, Bálint

    Journal of Statistical Physics, Vol. 65, Nos. 1/2, 1991 Upper Bound on the Condensate in the Hard by G. Roepstorf, we prove an upper bound for the amount of condensate in a hard-core Bose lattice gas on the amount of condensate for a Bose gas in R d, d/> 3, with arbitrary pair interaction. Exploiting the same

  4. A Semantic Image Annotation Model to Enable Integrative Translational Research

    E-Print Network [OSTI]

    Rubin, Daniel L.

    , MS1,2 Pattanasak Mongkolwat, PhD3 and David S. Channin, MD3 1 Department of Radiology, and 2 Center is not explicit in standard computer- accessible formats. We have developed an ontology- based representation that is not explicit and not accessible to machines. Images contain implicit knowledge about anatomy and abnormal

  5. VOLUME 87, NUMBER 20 P H Y S I C A L R E V I E W L E T T E R S 12 NOVEMBER 2001 Electromechanical Limits of Polymersomes

    E-Print Network [OSTI]

    VOLUME 87, NUMBER 20 P H Y S I C A L R E V I E W L E T T E R S 12 NOVEMBER 2001 Electromechanical, compared to 1 V for liposomes with d 3 nm. Nonetheless, electromechanical stresses at breakdown universally clearly demonstrated the electromechanical limits of lipid membranes via the combination of micropipette

  6. Noise in Disordered Systems: Higher Order Spectra in Avalanche Models

    E-Print Network [OSTI]

    Amit P. Mehta; Karin A. Dahmen; M. W. Weissman; Tim Wotherspoon

    2005-01-26

    We present a novel analytic calculation of the Haar power spectra, and various higher order spectra, of mean field avalanche models. We also compute these spectra from a simulation of the zero-temperature mean field RFIM and infinite range RFIM model for $d = 3$. We compare the results and obtain novel exponents.

  7. November 20th, 2013November 20 , 2013 BC Hydro Today

    E-Print Network [OSTI]

    November 20th, 2013November 20 , 2013 DRAFT 1 #12; BC Hydro Today FY 2013 IPPs in BC BC; BC Hydro serves 95 percent of the population in British Columbia1Columbia Load are split evenly (IPPs are d t t ith BC h d )3under contract with BC hydro)3 Limited transfer capability into BC from

  8. Simplified calculation method for design cooling loads in underfloor air distribution (UFAD) systems

    E-Print Network [OSTI]

    Schiavon, Stefano; Lee, Kwang Ho; Bauman, Fred; Webster, Tom

    2010-01-01

    and P.L. Linden, The EnergyPlus UFAD module. Proceedings ofUS, (2008) 23-28. EnergyPlus, Engineering Reference. U.S.uc/item/7gr8r3d3 EnergyPlus. Testing and Validation. http://

  9. MSc CSYM021 Java Programming GJH: 2008 MSc Computing (Internet Technology)

    E-Print Network [OSTI]

    Hill, Gary

    MSc CSYM021 ­ Java Programming © GJH: 2008 MSc Computing (Internet Technology) CSYM 021 Java Office (Open 10:00 - 15:00)). Aim: Produce a technical report and accompanying application using Java 2D/3D. Brief A: 2D Right (East) Panel: The Java Swing application is to include a Java 2D graphics maze

  10. MSc CSYM021 Java Programming GJH: 2009 MSc Computing (Internet Technology)

    E-Print Network [OSTI]

    Hill, Gary

    MSc CSYM021 ­ Java Programming © GJH: 2009 MSc Computing (Internet Technology) CSYM 021 Java Office (Open 10:00 - 15:00)). Aim: Produce a technical report and accompanying application using Java 2D/3D. Brief Produce a technical report and accompanying application using Java 3D. The application

  11. U-path: An undirected path-based measure of semantic similarity Bridget T. McInnes, PhD1

    E-Print Network [OSTI]

    Pedersen, Ted

    Pedersen, PhD2 , Ying Liu, PhD3 , Genevieve B. Melton, MD4 and Serguei V. Pakhomov, PhD4 1 Virginia Commonwealth University, Richmond, VA 2 University of Minnesota, Duluth, MN 3 The Advisory Board Company, San Francisco, CA 4 University of Minnesota, Minneapolis, MN Abstract In this paper, we present the results

  12. A Theory of Diagnosis as Hypothesis Refinement \\Lambda Peter Lucas

    E-Print Network [OSTI]

    Lucas, Peter

    and Meaning d 1 : influenza d 2 : tracheobronchitis d 3 : asthma f 1 : fever f 2 : sore throat f 3 : dyspnoea: ``Influenza causes fever and infection of the trachea and bronchial tree, which causes a sore throat, but if the patient suffers from asthma, dyspnoea will occur as well.'' In Figure 1(a), the directed graph

  13. A Guide for International PhD Gain a Doctorate

    E-Print Network [OSTI]

    Schüler, Axel

    A Guide for International PhD Candidates Gain a Doctorate in Leipzig internationalCentre|AAA 1 #12;Contents page Why choose the Universität Leipzig for my PhD? 3 Application and Admission 4 Which PhD programme is right for me? 4 5 steps to a PhD 5 Research Academy Leipzig 8 Internationale

  14. Regular Paths in SparQL: Querying the NCI Thesaurus Landon T. Detwiler1

    E-Print Network [OSTI]

    Washington at Seattle, University of

    Regular Paths in SparQL: Querying the NCI Thesaurus Landon T. Detwiler1 , Dan Suciu, PhD3 , James F can create views of the OWL version of the NCI Thesaurus that match the views generated by the web the matched triples. Some examples of triples from the National Cancer Institute (NCI) Thesaurus that would

  15. 17 March 2005 HPC Seminar, A. Gohm, IMGI 1 Atmospheric Modeling

    E-Print Network [OSTI]

    Gohm, Alexander

    ) Buchauer (1998) Mayr (1999) Schaffhauser (2000) Gohm (2004) Million model grid points nonlinearlinear 3D 2D 3D idealized flow realistic flow 1 grid 2 grid 3 grid 1 grid 6 grids 1 CPU 8-24 CPU Model setup CDC), currently maintained by the US spin-off company ATMET, and released under the GNU public license RAMS

  16. Charging-free electrochemical system for harvesting low-grade thermal energy

    E-Print Network [OSTI]

    Cui, Yi

    Charging-free electrochemical system for harvesting low-grade thermal energy Yuan Yanga,1 , Seok processes, environment, solar-thermal, and geothermal en- ergy (1­3). It is generally difficult to convert Cuib,d,3 , and Gang Chena,3 a Department of Mechanical Engineering, Massachusetts Institute

  17. Nucleus Implant Parameters Significantly Change the Compressive

    E-Print Network [OSTI]

    Karduna, Andrew

    stiffness of the denucleated intervertebral disc IVD when im- planted in the created nuclear defect into the custom made molds of three different diameters D1=15 mm, D2=16 mm, and D3=17 mm to achieve variation in the hydrogel implant diameter. The filled molds were gelled by six repeated cycles of freezing for 21 h at -19

  18. Adaptive Exchange of Distributed Partial Models@run.time for Highly Dynamic Systems

    E-Print Network [OSTI]

    : iliasg@d3s.mff.cuni.cz INRIA Lille / University of Lille 1, France, Email: filip other, the performance, energy and memory consumption as well as privacy are unnecessarily negatively subsystem has its own knowledge exchange policy and there is no central point of coordination from which

  19. Atmos. Chem. Phys., 8, 30333043, 2008 www.atmos-chem-phys.net/8/3033/2008/

    E-Print Network [OSTI]

    Meskhidze, Nicholas

    ­ Accepted: 15 May 2008 ­ Published: 18 June 2008 Abstract. Erythemaly weighted UV and total UV-A irra simultaneously to compare UV irradiances on vertical and horizontal planes. The en- tire range of such relative, then for vitamin D3 weighed UV irradiance. The minima of relative exposure (0.20­ 0.30) are almost the same for all

  20. Magnetohydrodynamics of Plasmas Author: Daniel Groselj

    E-Print Network [OSTI]

    ?umer, Slobodan

    for controlled thermonuclear1 fusion is [1] 2 1D + 3 1T 4 2He + n. (1) The total energy output2 (17.5 Me use-cases of MHD is the application to fusion plasmas, where the model can be used to accurately thermonuclear reactors. One of the most fundamental challenges of this field of reasearch is the study

  1. Michael De Angelo Professional Summary

    E-Print Network [OSTI]

    Yang, Zong-Liang

    at El Paso, 1983 M.S. Geophysics, The University of Texas at El Paso, 1988 Areas of Expertise A. 2-D/3-D. Development of seismic vector-wavefield technologies. D. Seismic data acquisition and 3D acquisition design, Pamphlets, Bulletins De Angelo, Michael, and Hardage, B. A., 2001, Using 3-D seismic coherency and stratal

  2. T.-B. Ho and Z.-H. Zhou (Eds.): PRICAI 2008, LNAI 5351, pp. 849858, 2008. Springer-Verlag Berlin Heidelberg 2008

    E-Print Network [OSTI]

    Cao, Longbing

    of intraday price manipulation is of great impor- tance to market integrity. However, it is very challenging to effectively detect price manipulation in real markets. Based on D3 M, this paper carries out a study on mining actionable local exceptional patterns indicating price manipulation on intraday trading data for market

  3. Enhanced gauge symmetry and winding modes in Double Field Theory

    E-Print Network [OSTI]

    G. Aldazabal; M. Graña; S. Iguri; M. Mayo; C. Nuñez; J. A. Rosabal

    2015-10-26

    We provide an explicit example of how the string winding modes can be incorporated in double field theory. Our guiding case is the closed bosonic string compactified on a circle of radius close to the self-dual point, where some modes with non-zero winding or discrete momentum number become massless and enhance the $U(1) \\times U(1)$ symmetry to $SU(2) \\times SU(2)$. We compute three-point string scattering amplitudes of massless and slightly massive states, and extract the corresponding effective low energy gauge field theory. The enhanced gauge symmetry at the self-dual point and the Higgs-like mechanism arising when changing the compactification radius are examined in detail. The extra massless fields associated to the enhancement are incorporated into a generalized frame with $\\frac{O(d+3,d+3)}{O(d+3)\\times O(d+3)}$ structure, where $d$ is the number of non-compact dimensions. We devise a consistent double field theory action that reproduces the low energy string effective action with enhanced gauge symmetry. The construction requires a truly non-geometric frame which explicitly depends on both the compact coordinate along the circle and its dual.

  4. UNIVERSIDADE FEDERAL DE MINAS GERAIS INSTITUTO DE CI

    E-Print Network [OSTI]

    Paiva Sanchis, Rémy de

    que elas sâ?ao funâ?ºcâ?oes analâ??�ticas. . No caso em que d # 3, obtemos cotas superior e inferior paraâ??avel em [0, 1] exceto no ponto crâ??�tico. Aparentemente, desde entâ?ao o problema de saber se #(p) â??e analâ??�tica

  5. Neosho County Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    Drawing II 3 ART 114 Drawing 2 3 ART 103 Art Concepts and Practice 3 ART 100 Design 2-D 3 ART 104 Art Ancient/Medieval 3 No equivalent Modern: 19th/20th/American/Photo 3 No equivalent East Asian 3 3 SOC 160 Social Problems/American Values 3 SOSC 220 Social Problems 3 PHSX 114 College Physics I 4

  6. Garden City Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    103 Art Concepts and Practice 3 ARTS 1243 Design 2-D 3 ART 104 Art Principals and Practice 3 ARTS 1293 2 3 No equivalent 1900-45 3 No equivalent Modern: 19th/20th/American/Photo 3 No equivalent GE3H Non Problems/American Values 3 SOCI 204 Social Problems 3 PHSX 111 Introductory Physics 3 PHYS 106 Descriptive

  7. Cloud County Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    ART 103 Art Concepts and Practice 3 AR 120 Design 2-D 3 ART 104 Art Principals and Practice 3 AR 171 History 2 3 No Equivalent 3 Ancient/Medieval 3 No Equivalent Modern: 19th/20th/American/Photo 3 to Sociology 3 PHSX 111 Introductory Physics 3 SC 109 Applied Physics 5 PHSX 114 College Physics I 4 SC 140

  8. Pratt Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    Concepts and Practice 3 ART 134 Design 2-D 3 ART 104 Art Principals and Practice 3 No equivalent HISTORY ART 177 Art History Renaissance to Modern 3 1900-45 3 No equivalent Modern: 19th/20th/American/Photo 3 SOC 233 Social Problems 3 PHSX 114 College Physics 4 PHS 251 General Physics 5 Outcome 2 GE12 MATH 101

  9. Garden City Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    103 Art Concepts and Practice 3 ARTS 1243 Design 2-D 3 ART 104 Art Principals and Practice 3 ARTS 1293 2 3 No equivalent Ancient/Medieval 3 No equivalent Modern: 19th/20th/American/Photo 3 No equivalent Social Problems 3 PHSX 111 Introductory Physics 3 PHYS 106 Descriptive Physics 3 PHSX 114 College Physics

  10. Labette Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    3 ART 103 Art Concepts and Practice 3 ART 107 Design 2-D 3 ART 104 Art Principals and Practice 3 ARTH HA 151 Art History 2 3 No equivalent 1900-45 3 No equivalent Modern: 19th/20th/American/Photo 3 College Physics 4 PHYS 201 College Physics I 5 PHSX 211 General Physics 4 PHYS 203 Engineering Physics 5

  11. Autosomal STR Variation in a Basque Population: Vizcaya Province

    E-Print Network [OSTI]

    Zlojutro, Mark; Roy, M.; Palikij, J.; Crawford, Michael H.

    2006-10-01

    We have characterized 68 unrelated Basque individuals from Vizcaya, Spain, for 13 tetrameric short tandem repeat (STR) loci: CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, TH01, TPOX, and VWA. Interpopulational...

  12. No. 01-1623 In the Supreme Court of the United States

    E-Print Network [OSTI]

    Kammen, Daniel M.

    . TAYLOR, PETITIONERS ON PETITION FOR A WRIT OF CERTIORARI TO THE UNITED STATES COURT OF APPEALS of Record MICHAEL CHERTOFF Assistant Attorney General MICHAEL R. DREEBEN Deputy Solicitor General MATTHEW D) ................................................................................ 3 Clark v. Johnson, 278 F.3d 459 (5th Cir. 2002), petition for cert. pending sub. nom. In re Taylor

  13. Aberconway Building C5 11 ARCCA C3 33

    E-Print Network [OSTI]

    Martin, Ralph R.

    ,Media and Cultural Studies D3 45 Joint Internal Audit Unit F3 66 Julian Hodge Building C4 14 Law D4,D4* 24 28 Road East A2 Crown Way C6 Crwys Road D5 Custom House Street E1 Dalcross Street E5 Dalton Street D5

  14. East Alumni Ave. Horticulture

    E-Print Network [OSTI]

    Vetter, Frederick J.

    , animal science (off Rte. 138 W.) Pharmacy Conference Center (Weldin House) 125 (D4) Planetarium 76 (B5 Buildings ** Adams Hall 1 (D3) * Adams House 112 (C6) ** Administrative Services, campus mail, printing services 109 (B2) Agronomy Field House (Plains Rd.) Agronomy Greenhouse (Plains Rd.) Alumni Center 87 (C6

  15. The Expression of D-Cyclin Genes Defines Distinct Developmental Zones in Snapdragon Apical Meristems and Is

    E-Print Network [OSTI]

    Murray, J.A.H.

    cyclins in turn activate cyclin-dependent protein kinases (CDKs) and thus drive cell cycle progression by the cycloidea gene. Expression of both cyclin D3 genes is reduced prior to the cessation of cell cycle activity in the length of the cell division cycle. For example, the duration of the cell cycle in Drosophila is increased

  16. Nucleosynthesis and the Chemical Evolution of the Universe

    E-Print Network [OSTI]

    Liske, Jochen

    AS2001 Nucleosynthesis and the Chemical Evolution of the Universe Tutorial 3 ­ Answers Question 1. Primordial nucleosynthesis ­ neutrons and protons get together to form the light nuclei D, 3 He, 4 He and 7 instability. Stellar nucleosynthesis ­ all other elements are synthesized inside stars or during supernova

  17. MATH225, Fall 2013 Name: Worksheet 1 (Review) Recitation Section

    E-Print Network [OSTI]

    MATH225, Fall 2013 Name: Worksheet 1 (Review) Recitation Section: Due Wednesday, Aug. 28th For full (1 - P)P dP (d) 3dy 5 + y2 #12;Algebra and Calculus Review In MATH225 you will need to use algebra may be graded more intensely than what you may have been accustomed to in your previous math classes

  18. FTIR and 27 Al MAS NMR analysis of the effect of framework Al-and Si-defects

    E-Print Network [OSTI]

    Sklenak, Stepan

    longer catalyst life-time. The micro-mesoporous H-ZSM-5 (synthesized by using carbon particles) exhib NMR and FTIR spectroscopy of OH groups and C,,N groups of adsorbed d3-acetonitrile were used, and particularly much lower catalyst life-time compared to the sample of similar composition and synthesis

  19. This CD-ROM contains spreadsheet versions of the tables included in: Smith, James E.; Heath, Linda S.; Skog, Kenneth E.; Birdsey, Richard A. 2006. Methods

    E-Print Network [OSTI]

    of each product. Table 8.--Fraction of carbon in primary wood products remaining in end uses up to 100 used for various end uses in the United States, and used for export, 1998. Table D3.--Half-life and harvested carbon, with standard estimates for forest types of the United States. Gen. Tech. Rep. NE-343

  20. Retinoic Acid Induction of Nuclear Envelope-Limited Chromatin Sheets in HL-60

    E-Print Network [OSTI]

    Olins, Ada L.

    vitamin D3, sodium butyrate, and 12-O-tetradecanoylphorbol-13-acetate (TPA) promote monocyticRetinoic Acid Induction of Nuclear Envelope-Limited Chromatin Sheets in HL-60 Ada L. Olins leukemic cell line (HL-60) to 1 M retinoic acid (RA) induces in vitro granulopoie- sis, including

  1. Tectonic and sedimentary response to oblique and incipient continental - continental collision the easternmost Mediterranean (Cyprus) 

    E-Print Network [OSTI]

    Kinnaird, Timothy C.

    , the ‘Cyprus Arc’. Early Pleistocene to Recent D3a transpression generated strike-slip faulting along E-W trends, conjugate left-lateral NNE-SSW-trending and right-lateral NNW-SSE-trending strike-slip faults and reactivated Tortonian D1 NW-SE and NE-SW...

  2. SLVS373 AUGUST 2001 3.3-V LDO AND DUAL SWITCH

    E-Print Network [OSTI]

    Berns, Hans-Gerd

    TPS2148 TPS2158 SLVS373 ­ AUGUST 2001 3.3-V LDO AND DUAL SWITCH FOR USB PERIPHERAL POWER MANAGEMENT 1www.ti.com FEATURES D Complete Power Management Solution for USB Bus-Powered Peripherals D 3.3-V Available in 8-Pin MSOP (PowerPAD) D ­40°C to 85°C Ambient Temperature Range APPLICATIONS D USB Peripherals

  3. Sandia Energy - EC Publications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    enXco A leader in renewable energy Tara Camacho-Lopez2015-04-06T22:15:34+00:00 Placeholder Download Filename 1-D-3-Maldonado1.pdf filesize 1.37 MB Version 1 date August 2, 2011...

  4. Spivack, Richard. "Innovation in Teleheath and the Role of the Government" in Future of Intelligent and Extelligent Health Environment. ed. Renata G. Bushko. IOS Press, 2005.

    E-Print Network [OSTI]

    and providers and has the potential to save costs; therefore, this technology must be a part of continuous for the Government1 2 Richard N. Spivack, PhD3 Economist, Economic Assessment Office of the Advanced Technology Program, National Institute of Standards and Technology, US Department of Commerce Abstract

  5. Predicting cyclone emissions with a new computer mode 

    E-Print Network [OSTI]

    Askew, James Wilson

    1993-01-01

    Cyclone emission tests were conducted on 1 D-3D and 2D-2D cyclones with varied outlet tube sizes and inlet velocities. Talc and wheat dusts were used in testing the laboratory scale models. Data from these tests were used in developing a...

  6. Kheshbn No. 102- Fall 1983 - Journal

    E-Print Network [OSTI]

    1983-01-01

    oVixtfü ,ix»-iypìx apy* UN inox ,*ip *iyw Viap m UN .a .K ,mrax yüyösV u t flö asra py Inox,, puya Tra» tü'Ua D3" ? wapaisya ,opt •nx^pra x u px inox ut px «pia ,ptes pp ps yaa-

  7. DISPERSIVE AND DISTRIBUTIVE MIXING CHARACTERIZATION IN EXTRUSION EQUIPMENT

    E-Print Network [OSTI]

    machinery performance has relied more on users' experience and trial and error experiments. Recently as an alternative and more efficient approach in studying the influence of design and processing conditions, defined as: old = D D + (3) can be used as a basic measure of mixing efficiency for the machine design

  8. versity of To of Medical S

    E-Print Network [OSTI]

    Goda, Keisuke

    therapy Associate Professor, Division of Stem Cell Processing & Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, IMSUT Makoto Otsu, M.D., Ph.D. 3 Application of iPS cells to retinal diseases Project Leader, Laboratory for Retinal Regeneration, Center for Developmental Biology, RIKEN

  9. MIT Research using High-Energy Density Plasmas at OMEGA and the NIF

    E-Print Network [OSTI]

    MIT Research using High-Energy Density Plasmas at OMEGA and the NIF Hans Rinderknecht Wednesday He D-D T 2.3 m SiO2 D3He gas 860 m #12;The High Energy Density Physics Division at MIT of Inertial Confinement Fusion (ICF) implosions VII. Proton Radiography #12;High Energy Density Physics

  10. SEVENTH FRAMEWORK PROGRAMME Capacities Specific Programme

    E-Print Network [OSTI]

    .: 227887 SERIES SEISMIC ENGINEERING RESEARCH INFRASTRUCTURES FOR EUROPEAN SYNERGIES Workpackage [WP3] Deliverable D3.2 [NA2.3] ­ [Report on the laboratory use of instrumentation and its management for seismic to the Networking Activity and aims at creating the conditions leading to the qualification - assessing

  11. SEVENTH FRAMEWORK PROGRAMME Capacities Specific Programme

    E-Print Network [OSTI]

    .: 227887 SERIES SEISMIC ENGINEERING RESEARCH INFRASTRUCTURES FOR EUROPEAN SYNERGIES Workpackage WP3 Deliverable 3.4 ­ Common Protocol for the Qualification of Research Infrastructures in Earthquake Engineering: Alessandro Bonzi - PeP Revision: Final January, 2013 #12;#12;D3.4 ­ Common Protocol for the Qualification

  12. Primary Radiation Therapy for Head-and-Neck Cancer in the Setting of Human Immunodeficiency Virus

    SciTech Connect (OSTI)

    Klein, Emily A.; Guiou, Michael; Farwell, D. Gregory; Luu, Quang; Lau, Derick H.; Stuart, Kerri; Vaughan, Andrew; Vijayakumar, Srinivasan; Chen, Allen M.

    2011-01-01

    Purpose: To analyze outcomes after radiation therapy for head-and-neck cancer among a cohort of patients with human immunodeficiency virus (HIV). Methods and Materials: The medical records of 12 patients with serologic evidence of HIV who subsequently underwent radiation therapy to a median dose of 68 Gy (range, 64-72 Gy) for newly diagnosed squamous cell carcinoma of the head and neck were reviewed. Six patients (50%) received concurrent chemotherapy. Intensity-modulated radiotherapy was used in 6 cases (50%). All patients had a Karnofsky performance status of 80 or 90. Nine patients (75%) were receiving antiretroviral therapies at the time of treatment, and the median CD4 count was 460 (range, 266-800). Toxicity was graded according to the Radiation Therapy Oncology Group / European Organization for the Treatment of Cancer toxicity criteria. Results: The 3-year estimates of overall survival and local-regional control were 78% and 92%, respectively. Acute Grade 3+ toxicity occurred in 7 patients (58%), the most common being confluent mucositis (5 patients) and moist skin desquamation (4 patients). Two patients experienced greater than 10% weight loss, and none experienced more than 15% weight loss from baseline. Five patients (42%) experienced treatment breaks in excess of 10 cumulative days, although none required hospitalization. There were no treatment-related fatalities. Conclusions: Radiation therapy for head-and-neck cancer seems to be relatively well tolerated among appropriately selected patients with HIV. The observed rates of toxicity were comparable to historical controls without HIV.

  13. Biomarkers of Radiosensitivity in A-Bomb Survivors Pregnant at the Time of Bombings in Hiroshima and Nagasaki

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Miles, Edward F.; Tatsukawa, Yoshimi; Funamoto, Sachiyo; Kamada, Naoko; Nakashima, Eiji; Kodama, Yoshiaki; Seed, Thomas; Kusonoki, Yoichiro; Nakachi, Kei; Fujiwara, Saeko; et al

    2011-01-01

    Purpose . There is evidence in the literature of increased maternal radiosensitivity during pregnancy. Materials and Methods . We tested this hypothesis using information from the atomic-bomb survivor cohort, that is, the Adult Health Study database at the Radiation Effects Research Foundation, which contains data from a cohort of women who were pregnant at the time of the bombings of Hiroshima and Nagasaki. Previous evaluation has demonstrated long-term radiation dose-response effects. Results/Conclusions . Data on approximately 250 women were available to assess dose-response rates for serum cholesterol, white blood cell count, erythrocyte sedimentation rate, and serum hemoglobin, and onmore »approximately 85 women for stable chromosome aberrations, glycophorin A locus mutations, and naïve CD4 T-cell counts. Although there is no statistically significant evidence of increased radiosensitivity in pregnant women, the increased slope of the linear trend line in the third trimester with respect to stable chromosome aberrations is suggestive of an increased radiosensitivity. « less

  14. Identification of full-length transmitted/founder viruses and their progeny in primary HIV-1 infection

    SciTech Connect (OSTI)

    Korber, Bette; Hraber, Peter; Giorgi, Elena; Bhattacharya, T

    2009-01-01

    Identification of transmitted/founder virus genomes and their progeny by is a novel strategy for probing the molecular basis of HIV-1 transmission and for evaluating the genetic imprint of viral and host factors that act to constrain or facilitate virus replication. Here, we show in a cohort of twelve acutely infected subjects (9 clade B; 3 clade C), that complete genomic sequences of transmitted/founder viruses could be inferred using single genome amplification of plasma viral RNA, direct amplicon sequencing, and a model of random virus evolution. This allowed for the precise identification, chemical synthesis, molecular cloning, and biological analysis of those viruses actually responsible for productive clinical infection and for a comprehensive mapping of sequential viral genomes and proteomes for mutations that are necessary or incidental to the establishment of HIV-1 persistence. Transmitted/founder viruses were CD4 and CCR5 tropic, replicated preferentially in activated primary T-Iymphocytes but not monocyte-derived macrophages, and were effectively shielded from most heterologous or broadly neutralizing antibodies. By 3 months of infection, the evolving viral quasispecies in three subjects showed mutational fixation at only 2-5 discreet genomic loci. By 6-12 months, mutational fixation was evident at 18-27 genomic loci. Some, but not all, of these mutations were attributable to virus escape from cytotoxic Tlymphocytes or neutralizing antibodies, suggesting that other viral or host factors may influence early HIV -1 fitness.

  15. Transgenic Mouse Model of Chronic Beryllium Disease

    SciTech Connect (OSTI)

    Gordon, Terry

    2009-05-26

    Animal models provide powerful tools for dissecting dose-response relationships and pathogenic mechanisms and for testing new treatment paradigms. Mechanistic research on beryllium exposure-disease relationships is severely limited by a general inability to develop a sufficient chronic beryllium disease animal model. Discovery of the Human Leukocyte Antigen (HLA) - DPB1Glu69 genetic susceptibility component of chronic beryllium disease permitted the addition of this human beryllium antigen presentation molecule to an animal genome which may permit development of a better animal model for chronic beryllium disease. Using FVB/N inbred mice, Drs. Rubin and Zhu, successfully produced three strains of HLA-DPB1 Glu 69 transgenic mice. Each mouse strain contains a haplotype of the HLA-DPB1 Glu 69 gene that confers a different magnitude of odds ratio (OR) of risk for chronic beryllium disease: HLA-DPB1*0401 (OR = 0.2), HLA-DPB1*0201 (OR = 15), HLA-DPB1*1701 (OR = 240). In addition, Drs. Rubin and Zhu developed transgenic mice with the human CD4 gene to permit better transmission of signals between T cells and antigen presenting cells. This project has maintained the colonies of these transgenic mice and tested the functionality of the human transgenes.

  16. Meteorological satellite photographs as indicators of cyclogenesis and the related cloud distribution and structure over the Gulf of Mexico: a case study. 

    E-Print Network [OSTI]

    Gosdin, Malcolm Edwood

    1964-01-01

    dl cd 4 cd M4J jcM S S ~ dj J3 dl ct Ql cd g~Wc-t bled S dj ~ 0 ct Ctl 0. + b04J S cd cd 0 4 4J jc Ch 0 0 0 bjj++ NH I a I 0 4J 0 dbms S cb QO cd Cb M S cd 044 cJ H )4J FE . A S ?0 4J 4J cd Jb cV C cO 0 S0c ql P Cb Jb 0 cd g 8... i 115' 110' 105' 100 95' Figure 7. NMC surface chart for 1200 GMT, 20 November 1962. 90' I 0 4J 0 J 0$ Cd cd O PW cd Cb Cl cd 0JJ 0 X cd' M g ld cd "0 ) O 9 Cd CV P, g cd P JJ 4J cd J3 C4 0 c0 0 CI0c cd H cJ cd Jb 0 cd 8 R 8 Cl cd...

  17. The Use of Synchrotron Infrared Microspectroscopy in the Assessment of Cutaneous T-cell Lymphoma vs. Pityriasis lichenoides Chronica

    SciTech Connect (OSTI)

    El Bedewi, A.; El Anany, G; El Mofty, M; Kretlow, A; Park, S; Miller, L

    2010-01-01

    The diagnosis of cutaneous lymphomas remains a challenge for both the clinician and dermatopathologist. To differentiate between frank malignant and premalignant lymphocytes within the skin. This study was performed on 20 patients with a mean age of 50 years. They were divided into two groups: mycosis fungoides (MF) (stage IA, IB and IIA) and pityriasis lichenoides chronica (PLC). Immunophenotyping using antibodies CD3, CD4, CD8, CD20 and CD30 was performed. Synchrotron Fourier transform infrared microspectroscopy (S-FTIRM) was performed on cell nuclei to assess chemical differences between MF and PLC cases as a potential complementary screening tool. Dermal spectra of both MF and PLC were compared using principal components analysis (PCA) of the S-FTIRM data. All PLC spectra was clustered together. However, the MF spectra formed two clusters, one that grouped with the PLC and the other grouped separately. Moreover, protein and nucleic acids showed highly significant differences between MF (IIA and IB), MF (IA) and PLC. The malignant transformation within lymphocytes was identifiable through the spectroscopic analysis of protein, RNA and DNA with S-FTIRM, making it a promising tool for classifying the progression of cutaneous T-cell lymphoma.

  18. Combined Treatment Effects of Radiation and Immunotherapy: Studies in an Autochthonous Prostate Cancer Model

    SciTech Connect (OSTI)

    Wada, Satoshi; Harris, Timothy J.; Tryggestad, Erik; Yoshimura, Kiyoshi; Zeng, Jing; Yen, Hung-Rong; Getnet, Derese; Grosso, Joseph F.; Bruno, Tullia C.; De Marzo, Angelo M.; and others

    2013-11-15

    Purpose: To optimize the combination of ionizing radiation and cellular immunotherapy using a preclinical autochthonous model of prostate cancer. Methods and Materials: Transgenic mice expressing a model antigen under a prostate-specific promoter were treated using a platform that integrates cone-beam CT imaging with 3-dimensional conformal therapy. Using this technology we investigated the immunologic and therapeutic effects of combining ionizing radiation with granulocyte/macrophage colony-stimulating factor-secreting cellular immunotherapy for prostate cancer in mice bearing autochthonous prostate tumors. Results: The combination of ionizing radiation and immunotherapy resulted in a significant decrease in pathologic tumor grade and gross tumor bulk that was not evident with either single-modality therapy. Furthermore, combinatorial therapy resulted in improved overall survival in a preventive metastasis model and in the setting of established micrometastases. Mechanistically, combined therapy resulted in an increase of the ratio of effector-to-regulatory T cells for both CD4 and CD8 tumor-infiltrating lymphocytes. Conclusions: Our preclinical model establishes a potential role for the use of combined radiation-immunotherapy in locally advanced prostate cancer, which warrants further exploration in a clinical setting.

  19. Chronic beryllium disease: Diagnosis and management

    SciTech Connect (OSTI)

    Rossman, M.D.

    1996-10-01

    Chronic beryllium disease is predominantly a pulmonary granulomatosis that was originally described in 1946. Symptoms usually include dyspnea and cough. Fever, anorexia, and weight loss are common. Skin lesions are the most common extrathoracic manifestation. Granulomatous hepatitis, hypercalcemia, and kidney stones can also occur. Radiographic and physiologic abnormalities are similar to those in sarcoidosis. While traditionally the pathologic changes included granulomas and cellular interstitial changes, the hallmark of the disease today is the well-formed granuloma. Immunologic studies have demonstrated a cell-mediated response to beryllium that is due to an accumulation of CD4{sup +} T cells at the site of disease activity. Diagnosis depends on the demonstration of pathologic changes (i.e., granuloma) and evidence that the granuloma was caused by a hypersensitivity to beryllium (i.e., positive lung proliferative response to beryllium). Using these criteria, the diagnosis of chronic beryllium disease can now be made before the onset of clinical symptoms. Whether, with early diagnosis, the natural course of this condition will be the same as when it was traditionally diagnosed is not known. Currently, corticosteroids are used to treat patients with significant symptoms or evidence of progressive disease. 21 refs.

  20. Existence, uniqueness, and parametrization of Lagrangian invariant subspaces

    E-Print Network [OSTI]

    Freiling, G.; Mehrmann, V.; Xu, Hongguo

    2002-05-10

    BPB4C2 D2 C0B5 C0 CXD7 C0CTD6D1CXD8CXCPD2B8 DBCWCTD6CT C2 D2 BP CW BC A0C1 D2 C1 D2 BC CX B8 C1 D2 CXD7 D8CWCT D2A2D2 CXCSCTD2D8CXD8DD D1CPD8D6CXDC CPD2CS D8CWCT D7D9D4CTD6D7CRD6CXD4D8 C0 CSCTD2D3D8CTD7 D8CWCT CRD3D2CYD9CVCPD8CT D8D6CPD2D7D4D3D7CTBA... CACXCRCRCPD8CX CTD5D9CPD8CXD3D2D7 D3CU D8CWCT CUD3D6D1 BT C0 CG B7CGBTA0CGC5CGB7BZ BPBCBMB4BDBABDB5 C1D8 CXD7 DBCTD0D0 CZD2D3DBD2 CJBDBHCL D8CWCPD8 CXCU CG BP CG C0 D7D3D0DACTD7 B4BDBABDB5B8 D8CWCTD2 C0 AK C1 D2 BC A0CG C1 D2 AL BP AK C1 D2 BC A0CG C1 D2 ALAK...

  1. Massive "spin-2" theories in arbitrary $D \\ge 3$ dimensions

    E-Print Network [OSTI]

    D. Dalmazi; A. L. R. dos Santos; E. L. Mendonça

    2014-08-28

    Here we show that in arbitrary dimensions $D\\ge 3$ there are two families of second order Lagrangians describing massive "spin-2" particles via a nonsymmetric rank-2 tensor. They differ from the usual Fierz-Pauli theory in general. At zero mass one of the families is Weyl invariant. Such massless theory has no particle content in $D=3$ and gives rise, via master action, to a dual higher order (in derivatives) description of massive spin-2 particles in $D=3$ where both the second and the fourth order terms are Weyl invariant, contrary to the linearized New Massive Gravity. However, only the fourth order term is invariant under arbitrary antisymmetric shifts. Consequently, the antisymmetric part of the tensor $e_{[\\mu\

  2. Electromagnetic Casimir effect on the boundary of a D-dimensional cavity and the high temperature asymptotics

    E-Print Network [OSTI]

    L. P. Teo

    2013-04-29

    We consider the finite temperature Casimir stress acting on the boundary of a D>=3 dimensional cavity due to the vacuum fluctuations of electromagnetic fields. Both perfectly conducting and infinitely permeable boundary conditions are considered, and it is proved that they correspond mathematically to the relative and absolute boundary conditions. The divergence terms of the Casimir free energy are related to the heat kernel coefficients of the Laplace operator. It is shown that the Casimir stress is free of divergence if and only if D is exactly three. The high temperature asymptotics of the regularized Casimir free energy are also found to depend on the heat kernel coefficients. When D>3, renormalization is required to remove terms of order higher than or equal to T^2.

  3. Nuclear processes in magnetic fusion reactors with polarized fuel

    E-Print Network [OSTI]

    Michail P. Rekalo; Egle Tomasi-Gustafsson

    2000-10-16

    We consider the processes $d +d \\to n +{^3He}$, $d +{^3He} \\to p +{^4He}$, $d +{^3H} \\to n +{^4He}$, ${^3He} +{^3He}\\to p+p +{^4He}$, ${^3H} +{^3He}\\to d +{^4He}$, with particular attention for applications in fusion reactors. After a model independent parametrization of the spin structure of the matrix elements for these processes at thermal colliding energies, in terms of partial amplitudes, we study polarization phenomena in the framework of a formalism of helicity amplitudes. The strong angular dependence of the final nuclei and of the polarization observables on the polarizations of the fuel components can be helpful in the design of the reactor shielding, blanket arrangement etc..We analyze also the angular dependence of the neutron polarization for the processes $\\vec d +\\vec d \\to n +{^3He}$ and $\\vec d +\\vec {^3H} \\to n +{^4He}$.

  4. Polchinski-Strassler does not uplift Klebanov-Strassler

    E-Print Network [OSTI]

    Iosif Bena; Mariana Grana; Stanislav Kuperstein; Stefano Massai

    2013-09-25

    Anti-D3-branes at the tip of the Klebanov-Strassler solution with D3-charge dissolved in fluxes give rise, in the probe approximation, to a metastable state. The fully back-reacted smeared solution has singular three-form fluxes in the IR, whose presence suggests a stringy resolution by brane polarization a la Polchinski-Strassler. In this paper we show that there is no polarization into anti-D5-branes wrapping the $S^2$ of the conifold at a finite radius. The singularities therefore do not seem to be physical, signaling that antibranes cannot be used to uplift AdS and obtain a very large landscape of de Sitter vacua in string theory.

  5. The BCS - BEC Crossover In Arbitrary Dimensions

    E-Print Network [OSTI]

    Zohar Nussinov; Shmuel Nussinov

    2005-10-11

    Cold atom traps and certain neutron star layers may contain fermions with separation much larger than the range of pair-wise potentials yet much shorter than the scattering length. Such systems can display {\\em universal} characteristics independent of the details of the short range interactions. In particular, the energy per particle is a fraction $\\xi$ of the Fermi energy of the free Fermion system. Our main result is that for space dimensions D smaller than two and larger than four a specific extension of this problem readily yields $\\xi=1$ for all $D \\le 2$ whereas $\\xi$ is rigorously non-positive (and potentially vanishing) for all $ D \\ge 4$. We discuss the D=3 case. A particular unjustified recipe suggests $\\xi=1/2$ in D=3.

  6. Directional sensitivity of velocity sense in lateral trunk flexion

    E-Print Network [OSTI]

    Soltys, Joseph S.; Wilson, Sara E.

    2008-01-04

    "7$9&/439/*’03#U’8/9+"0#’8"0’ "99D%/+3"4/**,’0$*/+$A’*"?’F/9U’A3#"0A$0#)’Ergonomics, 38cQg-’IOOPNGJ)’ ./00/#-’2)’()-’f’2"4:#/7-’5)’1)’cG^LMg)’R*$S3F3*3+,’/4A’cNg...+3"4-’/A/%+/+3"4-’/4A’$4&/49$7$4+)’Journal of Spinal Disorders, 5cNg-’ ILIPIL^e’A3#9D##3"4’I^O)’ 5/4\\/F3-’.)’.)’cG^^QFg)’X&$’#+/F3*3]34:’#,#+$7’"8’+&$’#%34$)’5/0+’[[)’j$D+0/*’]"4$’/4A’ 34#+/F3*3+,’&,%"+&$#3#)’Journal of Spinal Disorders, 5cNg-’I^JPI^Me’A3...

  7. Review: Avgust Pavel: Prekmurska Slovenska Slovnica. Vend Nyelvtan

    E-Print Network [OSTI]

    Šek Mertü k, Polonca

    2014-06-25

    #3;SUHG#3;QMHQLP#3; QDVWDQNRP#15;#3;åH#3;Y#3;þDVX#3;âWHIDQD#3;.]PLþD#15;#3; GD#3;EL#3;ODKNR#3;ELO#3;SUHNPXUVNL#3;NQMLåQL#3;MH]LN#3; QRUPLUDQ#3;åH#3;RE#3;VYRMHP#3;QDVWDQNX#3;#11;#20;#26;#26;#20;#12;#17;#3; 6ORYQLFD#3;MH#3;QDVWDOD#3;ªY#3;QHXJRGQHP#3;þ...DYORYH#3; VORYQLFH#29;#3; URNRSLV#3; VH#3; QDKDMD#3; Y#3; 3DYORYL#3; VSRPLQVNL#3; VREL#3; QD#3;.DWHGUL#3; ]D#3; VODYLVWL-­ NR#3;8QLYHU]LWHWQHJD#3; VUHGLãþD#3;6DYDULD#3; Y#3; 6RPERWHOX#15;#3; WLSNRSLV#3; SD#3; KUDQL#3;0X]HM#3; 6DYDULD#3;Y#3;6RPERWHOX#17...

  8. Triviality of the BCS-BEC crossover in extended dimensions: Implications for the ground state energy

    SciTech Connect (OSTI)

    Nussinov, Zohar [Department of Physics, Washington University, St. Louis, Missouri 63160-4899 (United States); Nussinov, Shmuel [School of Physics and Astronomy, Tel Aviv University, Ramat-Aviv, Tel Aviv 69978 (Israel)

    2006-11-15

    Cold atom traps and certain neutron star layers may contain fermions with separation much larger than the range of pairwise potentials yet much shorter than the scattering length. Such systems can display universal characteristics independent of the details of the short range interactions. Our main result is that for space dimensions D smaller than two and larger than four a specific extension of this problem is amenable to exact results. In particular, the energy per particle at the BCS-BEC crossover point is equal to the energy of the free fermion system in all D{<=}2 whereas this energy is rigorously nonpositive (and potentially vanishing) in all D{>=}4. We discuss the D=3 case. A particular unjustified recipe suggests {xi}=1/2 in D=3.

  9. Gauge Theories on the Coulomb branch

    E-Print Network [OSTI]

    John H. Schwarz

    2014-08-05

    We construct the world-volume action of a probe D3-brane in $AdS_5 \\times S^5$ with $N$ units of flux. It has the field content, symmetries, and dualities of the $U(1)$ factor of ${\\cal N} =4$ $U(N+1)$ super Yang--Mills theory, spontaneously broken to $U(N) \\times U(1)$ by being on the Coulomb branch, with the massive fields integrated out. This motivates the conjecture that it is the exact effective action, called a `highly effective action' (HEA). We construct an $SL(2,Z)$ multiplet of BPS soliton solutions of the D3-brane theory (the conjectured HEA) and show that it reproduces the electrically charged massive states that have been integrated out as well as magnetic monopoles and dyons. Their charges are uniformly spread on a spherical surface, called a `soliton bubble', which is interpreted as a phase boundary.

  10. Calibrations, Monopoles and Fuzzy Funnels

    E-Print Network [OSTI]

    Neil R. Constable; Neil D. Lambert

    2002-07-09

    We present new non-Abelian solitonic configurations in the low energy effective theory describing a collection of N parallel D1--branes. These configurations preserve 1/4, 1/8, 1/16 and 1/32 of the spacetime supersymmetry. They are solutions to a set of generalised Nahm's equations which are related to self-duality equations in eight dimensions. Our solutions represent D1--branes which expand into fuzzy funnel configurations ending on collections of intersecting D3--branes. Supersymmetry dictates that such intersecting D3--branes must lie on a calibrated three-surface of spacetime and we argue that the generalised Nahm's equations encode the data for the construction of magnetic monopoles on the relevant three-surfaces.

  11. Observation of D??K??(') and Search for CP Violation in D?????(') Decays

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Won, E.; Ko, B. R.; Adachi, I.; Aihara, H.; Arinstein, K.; Asner, D. M.; Aushev, T.; Bakich, A. M.; Barberio, E.; Bay, A.; et al

    2011-11-21

    We report the first observation of the doubly Cabibbo-suppressed decays D??K??(') using a 791 fb?¹ data sample collected with the Belle detector at the KEKB asymmetric-energy e?e? collider. The ratio of the branching fractions of doubly Cabibbo-suppressed relative to singly Cabibbo-suppressed D?????(') decays are B(K??)/B(D?????)=(3.06±0.43±0.14)% and B(K??('))/B(D?????(')) = (3.77±0.39±0.10)%. From these, we find that the relative final-state phase difference between the tree and annihilation amplitudes in D? decays, ?TA, is (72±9)° or (288±9)°. We also report the most precise measurements of CP asymmetries to date: AD?CP=(+1.74±1.13±0.19)% and AD???+?'CP = (-0.12±1.12±0.17)%.

  12. Interview with Colin Jerolmack

    E-Print Network [OSTI]

    Jerolmack, Colin; Craft, Rachel; Ordner, James

    2010-01-01

    analysts, and describe these problems, or should we take an ethical stance and attempt to activate change? JEROLMACK:#3;7KLV#3; LV#3; D#3; FODVVLF#3; TXHVWLRQ#30;#3; WKLV#3; LV#3; D#3;:HEHULDQ#3; TXHVWLRQ#3;RI#3;WKH#3;IDFW#16;YDOXH#3...#3;SDUW#3;RI#3;WKH#3;SXEOLF#3;VRFLRORJ\\#3;SURMHFW#3;WKDW¶V#3;NLQG#3;RI#3;KRW#3;ULJKW#3;QRZ" -(52/0$&.#29;#3;1RW#3;\\HW#17;#3;#3;,#3;PHDQ#15;#3;\\RX#3;NQRZ#15;#3;DJDLQ#15;#3;,¶P#3;IRUWXQDWH#3; HQRXJK#3;WR#3;EH#3;LQ#3;WKH#3;SRVLWLRQ#3;,¶P#3;LQ#3;WR#3;KDYH...

  13. 3-point temperature anisotropies in WMAP: Limits on CMB non-Gaussianities and non-linearities

    E-Print Network [OSTI]

    E. Gaztanaga; J. Wagg

    2003-06-12

    We present a study of the 3-pt angular correlation function w_3= of (adimensional) temperature anisotropies measured by the Wilkinson Microwave Anisotropy Probe (WMAP). Results can be normalized to the 2-point function w_2 = in terms of the hierarchical: q_3 ~ w_3/w_2^2 or dimensionless: d_3 ~ w_2/w_2^{3/2}$ amplitudes. Strongly non-Gaussian models are generically expected to show d_3 > 1 or q_3 > 10^3 d_3. Unfortunately, this is comparable to the cosmic variance on large angular scales. For Gaussian primordial models, q_3 gives a direct measure of the non-linear corrections to temperature anisotropies in the sky: delta = delta_L + f_{NLT} (delta_L^2 - ) with f_{NLT} = q_3/2 for the leading order term in w_2^2. We find good agreement with the Gaussian hypothesis d_3 ~ 0 within the cosmic variance of LCDM simulations (with or without a low quadrupole). The strongest constraints on q_3 come from scales smaller than 1 degree. We find q_3 =19 +/-141 for (pseudo) collapsed configurations and an average of q_3 = 336 +/-218 for non-collapsed triangles. The corresponding non-linear coupling parameter, f_{NL}, for curvature perturbations Phi, in the Sachs-Wolfe (SW) regime is: f_{NL}^{SW} = q_3/6, while on degree scales, the extra power in acoustic oscillations produces f_{NL} ~ q_3/30 in the LCM model. Errors are dominated by cosmic variance, but for the first time they begin to be small enough to constrain the leading order non-linear effects with coupling of order unity.

  14. (-]D,t) and (-]D, He-3) Reactions on C-12, O-16, Mg-24, and Ca-40 at 29 Mev 

    E-Print Network [OSTI]

    Cossairt, J. D.; Talley, S. B.; May, D. P.; Tribble, Robert E.; Spross, R. L.

    1978-01-01

    ~ col ~ ~ l A ~ l e4 chic@ Inly cn les col a ant n anl a min chica 'VO O OO lO.O COSSAIRT ALLE Y, MAy T RIBBLE AND SPROSS ~ S. IO.O IO.O IO.Q l.O ?l.O I.Q N ?IQ b l.O ?O. l Q. i ?O. i O. I l20 (deg) FIG. 3. ?gular d 2~(d 3H gf ributions...

  15. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    SciTech Connect (OSTI)

    Gemelli, Claudia, E-mail: claudia.gemelli@unimore.it [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy); Center for Regenerative Medicine, University of Modena and Reggio Emilia, Via Gottardi 100, 41125 Modena (Italy); Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy)

    2013-12-10

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling.

  16. Important Basic Equations for Order of Magnitude Estimation Conservation Laws

    E-Print Network [OSTI]

    Nimmo, Francis

    area 4r2 or d2 Sphere: volume 4 3r3 or 1 6d3 Forces Newton's Second Law F = ma Force due to gravity Fg = mg = Gm1m2 r2 Drag force Fd = 1 2cDAv2 Frictional force Ff = cf FN Buoyant force Fb = fluidV g valid for non-relativistic systems) · Energy · Linear momentum · Angular momentum Quantities Force mass

  17. 611: Electromagnetic Theory Problem Sheet 4

    E-Print Network [OSTI]

    Pope, Christopher

    611: Electromagnetic Theory Problem Sheet 4 (1a) The angular momentum 3-vector L is defined by Li) Prove from the above that for the electromagnetic field, L = 1 4 r × (E × B) d3 x (b) Prove that dR dt = P E where R is the centre of mass of the electromagnetic field, defined by R Wd3x = rWd3x

  18. The Impact of Extracellular Matrix Stiffness on Angiogensis 

    E-Print Network [OSTI]

    Lee, Po-Feng 1976-

    2012-12-06

    -110], specifically migration [107], drug responsiveness [108] and differentiation [109]. There is growing interest in 10 tissue engineering in designing the physical properties of a biomaterial scaffold, including topographical and mechanical properties... 2D/3D polymeric biomaterials used for tissue engineering or mechano-sensitivity studies consist of synthetic and natural polymeric materials. Synthetic polymeric material includes polyacrylamide (PA) [117, 120-122], polyelectrolyte multilayer film...

  19. Pan American Advanced Studies Institute Program: Process Modeling and Optimization for Energy and Sustainability

    E-Print Network [OSTI]

    Grossmann, Ignacio E.

    chemicals and 6 reactions: Products P1, P2, P3, P4, P5 and P6 can be produced from raw materials A, B, C, DC + 2P1 P3 + P5 (R4) 6E P6 (R5) 2D + 3P2 3P6 (R6) Given the availability (ai) of raw materials is the subset of raw materials and FPI is the subset of final products. Mass balance constraints can

  20. High-pressure effect on dislocation density in nanosize diamond crystals C. Panteaa,*, J. Gubiczab,c

    E-Print Network [OSTI]

    Gubicza, Jenõ

    materials are different from the coarse-grained materials. Diamond nanosize crystals attracted a lot manufacturing, high-pressure and high-tempera- ture treatment may affect structure and properties of crystalsD2 (3 GPa), nD3 (5.5 GPa), and nD4 (8.0 GPa) and the raw powder nD0. In the case of experiments

  1. L. Ballou Name____________________________ Math 132 Calculus II February 25, 2015

    E-Print Network [OSTI]

    Borchers, Brian

    required to pump the upper 3 feet of the water out of the top of an upright conical tank with top radius 4 indicated below. For each case, set up the integral; but do NOT evaluate. a. 1y . b. 6y c. 0x d. 3x #12 of a trapezoid whose top is 320 feet long, whose base is 200 feet long, and whose height is 80 feet, given

  2. L. Ballou Name____________________________ Math 132 Calculus II February 25, 2015

    E-Print Network [OSTI]

    Borchers, Brian

    the work required to pump all the water out of the top of an upright conical tank that is 12 feet high and has a radius of 6 feet at the top(let the weight- density of water be 62.4 lbs/ft3). Set up indicated below. For each case, set up the integral; but do NOT evaluate. a. 1y . b. 6y c. 0x d. 3x Solution

  3. J.M. Butler Florida Statewide DNA Training May 12-13, 2008 http://www.cstl.nist.gov/biotech/strbase/training.htm 1

    E-Print Network [OSTI]

    J.M. Butler ­ Florida Statewide DNA Training May 12-13, 2008 http://www.cstl.nist.gov/biotech, same POP6 polymer, ... #12;J.M. Butler ­ Florida Statewide DNA Training May 12-13, 2008 http://www.cstl.nist.gov/biotech from http://www.cstl.nist.gov/biotech/strbase/NISTpub.htm D18S51D21S11 D3S1358 vWA D5S818 D8S1179Amel D

  4. differences between 'the probability models that the Bayesians use and the onesthat the frequentists use to articulate their very different

    E-Print Network [OSTI]

    Fitelson, Branden

    probability of only 0.02. Now suppose that a patient, Mr Doe, is given the test. On learning that the result.95 0.05 Disease D , Absent 0.02 0.98 following conclusions: 1. Mr Doe prot)ablyldoesnot have D. 2. Mr Doe should be treated for D. 3. The test result is evidence that Mr Doe has D. Which, if any

  5. Preprint typeset in JHEP style. -PAPER VERSION hep-ph/yymmnnn Glueballs and AdS/CFT

    E-Print Network [OSTI]

    Terning, John

    Preprint typeset in JHEP style. - PAPER VERSION hep-ph/yymmnnn Glueballs and AdS/CFT John Terning T around the D3-branes. In this limit the metric reduces to that of AdS 5 #2; S 5 , where AdS 5 is a 5D coupling constant and d 5 is the line element on S 5 . The boundary of AdS 5 at #26; = 1 is a at 4D space

  6. The Ether Extract and the Chloroform Extract of Soils. 

    E-Print Network [OSTI]

    Fraps, G. S.; Rather, J. B.

    1913-01-01

    U T I N O . L N 15U L T J A U RY ,9 3L D T 9 J V S J D 3L Y FT C . J 1913 TEXAS AGRICULTURAL EXPERIMENT STATIONS. GOVERNING BOARD. (Board of Directors, A . and M . College.) TH EH RXACNDLO President..................................................................................................Entomologist PH EH RFDDUGO B. S ........................................................................................................ Agronomist lH MMH EIg)ST??O (C H 1)................................................P lant Pathologist and Physiologist o Uu...

  7. U.Va. Map : McCormick Road Area 1 (A4) Albert H. Small Building

    E-Print Network [OSTI]

    Zhigilei, Leonid V.

    ) Monroe Hill House/Range (MH3) 32 (B5) Montebello 33 (F1) Morea 34 (G2) Nameless Field 35 (F5) New Cabell*) 14 (F1) 108 Cresap Road 51 (C3) Dell 1 (Studio Art) 52 (C3) Dell 2 (Studio Art) 15 (D3) Dell Science Building (MSB) 25 (E4) Maury Hall (MRY*) 27 (B4) Mechanical Engineering (MEC) 28 (F2) Memorial

  8. A B C D E F G H CSULB "Campus Connection" Stop

    E-Print Network [OSTI]

    Sorin, Eric J.

    LOS CERRITOS HALL B5 DC DANCE CENTER F1 MHB MCINTOSH HUMANITIES BLDG F8 DESN DESIGN H5 MIC CENTER E9 EN2 ENGINEERING 2 G4 NUR NURSING C5 EN3 ENGINEERING 3 G4 OP OUTPOST G5 EN4 ENGINEERING 4 G4 PTS PARKING & TRANSPORTATION SERVICES D3 ECS ENGINEERING AND COMPUTER SCIENCE H4 PARKING STRUCTURE 1 D2 ET

  9. d upstream downstream disturbance

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    microphone Cm (s) C e (s) Controller (a) m Pmd (s) d Cm (s) Pmu (s) P ed (s) u P eu (s) e C e (s) (b) Figure) #12; y 2 =m Pmd (s) w 1 =d w 2 D 2 C m (s) Pmu (s) z 2 P ed (s) D 1 W 2 W 3 z 3 D 3 w 3 1 0 0005 1 0

  10. Well control simulation with the Macintosh II computer 

    E-Print Network [OSTI]

    Wallis, Gregory Tad

    1991-01-01

    B-1 Effect of Location on Geothermal Gradient C-1 Methane-Water Interfacial Tension as a Function of Pressure D-1 Bubble Migration Velocity in Plain Water D-2 Slug Migration Velocity in Plain Water D-3 Bubble Migration Velocity in XC Polymer... Work CONCLUSIONS NOMENCLATURE REFERENCES Page . 53 76 80 83 100 104 104 126 130 136 136 139 141 147 APPENDIX A: DRILLING AND CIRCULATION EQUATIONS . . . . I 4 9 APPENDIX B: KICK INFLUX APPENDIX C: GAS BUBBLE MIGRATION APPENDIX D...

  11. CX-004109: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Phase 2 - A 3D-3C Reflection Seismic Survey and Data Integration to Identify the Seismic Response of Fractures and Permeable Zones over a Known Geothermal Resource: Soda Lake, Churchill County, NevadaCX(s) Applied: B3.1, B3.7Date: 09/29/2010Location(s): Soda Lake, NevadaOffice(s): Energy Efficiency and Renewable Energy, Golden Field Office

  12. CX-006567: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Recovery Act: A 3D-3C Reflection Seismic Survey and Data Integration to Identify the Seismic Response of Fractures and Permeable Zones Over a Known Geothermal Resource: Soda Lake, Churchill County, NevadaCX(s) Applied: A9, B3.1, B3.7Date: 08/24/2011Location(s): Churchill County, NevadaOffice(s): Energy Efficiency and Renewable Energy, Golden Field Office

  13. Anti-de Sitter black holes in supergravity 

    E-Print Network [OSTI]

    Chong, Zhiwei

    2009-06-02

    -Generating Procedure . . . . . . . . . . . . . . . . 22 1. O(4,4) Symmetry of the Reduced D = 3 Theory . . . 23 2. O(1,1)4 Transformation of a Reduced Uncharged Solution . . . . . . . . . . . . . . . . . . . . . . . . . . 30 C. 4-Charge Rotating NUT Solution... of supersymmetric five-dimensional AdS black holes and that calculated from the counting of microstates in the D-brane models involving giant gravitons in the very recent paper [22]. In Chapter IV, we will present the details in constructing 12 these five...

  14. Site and Oxidation-State Specificity Yielding Dimensional Control in Perovskite Ruthenates

    E-Print Network [OSTI]

    Poeppelmeier, Kenneth R.

    Site and Oxidation-State Specificity Yielding Dimensional Control in Perovskite Ruthenates Job T perovskite, Sr3CaRu2O9. Ruthenium's unusual ability to readily adopt both IV(d4) and V(d3) oxidation states-sites of the perovskite lattice (Figure 1). Similarly ordered materials based on Nb5+ or Ta5+ are known and serve as good

  15. Computational Intelligence A Logical Approach

    E-Print Network [OSTI]

    Poole, David

    to be heating. Using CILog write axioms that let the system determine whether kettles are heating. Your program for Chapter 3 2 t1 t2 t3 floor p1 d1 d2d3 p2 bath shower sink p3 Figure 1: The Plumbing Domain CILog code a shower, bath denotes a bath, sink denotes a sink and floor denotes the floor. Figure 1 is intended

  16. Measurement of the 3s1/2-3p3/2 resonance line of sodiumlike Eu52+

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Träbert, E.; Beiersdorfer, P.; Hell, N.; Brown, G. V.

    2015-08-20

    We have measured the 3s1/2-3p3/2 transition in sodiumlike Eu52+ situated at 41.232 Å with an uncertainty of 73 ppm. Our measurement extends previous high-precision measurements into the 561/2-3p3/2 and 3p1/2-3d3/2 transitions in the neighboring magnesiumlike, aluminumlike, and siliconlike europium ions.

  17. A Multinuclear Copper(I) Cluster Forms the Dimerization Interface in Copper-Loaded Human Copper Chaperone for Superoxide Dismutase

    SciTech Connect (OSTI)

    Stasser, J.P.; Siluvai, G.S.; Barry, A.N.; Blackburn, N.J.

    2009-06-04

    Copper binding and X-ray aborption spectroscopy studies are reported on untagged human CCS (hCCS; CCS = copper chaperone for superoxide dismutase) isolated using an intein self-cleaving vector and on single and double Cys to Ala mutants of the hCCS MTCQSC and CSC motifs of domains 1 (D1) and 3 (D3), respectively. The results on the wild-type protein confirmed earlier findings on the CCS-MBP (maltose binding protein) constructs, namely, that Cu(I) coordinates to the CXC motif, forming a cluster at the interface of two D3 polypeptides. In contrast to the single Cys to Ser mutations of the CCS-MBP protein (Stasser, J. P., Eisses, J. F., Barry, A. N., Kaplan, J. H., and Blackburn, N. J. (2005) Biochemistry 44, 3143-3152), single Cys to Ala mutations in D3 were sufficient to eliminate cluster formation and significantly reduce CCS activity. Analysis of the intensity of the Cu-Cu cluster interaction in C244A, C246A, and C244/246A variants suggested that the nuclearity of the cluster was greater than 2 and was most consistent with a Cu4S6 adamantane-type species. The relationship among cluster formation, oligomerization, and metal loading was evaluated. The results support a model in which Cu(I) binding converts the apo dimer with a D2-D2 interface to a new dimer connected by cluster formation at two D3 CSC motifs. The predominance of dimer over tetramer in the cluster-containing species strongly suggests that the D2 dimer interface remains open and available for sequestering an SOD1 monomer. This work implicates the copper cluster in the reactive form and adds detail to the cluster nuclearity and how copper loading affects the oligomerization states and reactivity of CCS for its partner SOD1.

  18. Housing Checklist for Older Adults. 

    E-Print Network [OSTI]

    Anonymous,

    1980-01-01

    .1215 - HOUSING CHECKLIST FOR OLDER ADULTS ------ This checklist will help you evaluate a home to deter mine whether it meets the needs of the elderly and handicapped and furthers their independent living. It will also be helpful in evaluating a new house..., apart ment, mobile home or other facility for retirement living. Each statement reflects a desirable feature for the elderly and handicapped. Mark an X in the appropriate box according to the following: Yes D No D 3 Yes No LOCATION...

  19. Project Number: 215219 Project Acronym: SOA4All

    E-Print Network [OSTI]

    Hitzler, Pascal

    ______________________________________________ 14 3.4 WSML-DL V2.0 SYNTAX DEFINITION ________________________________ 15 3.5 ALGORITHMISATION.1.3 Defining the Features of the WSML-DL v2.0 Language Activity N: Activity 2 - Core Research and Development-2013) Dissemination Level PU Public X #12;SOA4All ­FP7 ­ 215219 ­ D3.1.3 Defining the Features of the WSML-DL v2.0

  20. Supplement of Atmos. Chem. Phys., 14, 46434659, 2014 http://www.atmos-chem-phys.net/acp-14-4643-2014/

    E-Print Network [OSTI]

    Meskhidze, Nicholas

    of the three ULSD used with D1, D2 and D3 are provided in Table S.1, and a more detailed analysis is given with D4 or D5. Table S.1 Selected characteristics of the three ULSD fuels used in the HDDV smog chamber experiments. A more detailed chemical analysis is provided in Figure S.1 of the SI. low aromatic ULSD mid

  1. Nome Issue 11 

    E-Print Network [OSTI]

    Multiple Contributors

    1988-01-01

    '. . enzo' c acid (PARA)s 20 mgI inositol~ 1000 mgJ methionine~ 7. 5 gmJ gIycine~ 4. 0 gmJ Delstorol (vitauIn D3 ~ 7. 5 gmJ alpha tocopheryl ace ate~ 6 mg J vitamin A (P~rnadry)~ 10s 000 units/gm, ( 1 gm I vitamin P 12~ 30 gamma I cho lire s 2000 mg I...

  2. Temperature dependent gain of the atomic xenon laser Gregory A. Hebne?)

    E-Print Network [OSTI]

    Kushner, Mark

    Temperature dependent gain of the atomic xenon laser Gregory A. Hebne?) Sandia National(3/2),-6p(5/2),] and 2.03 pm [5d(3/2)t- 6p( 3/2) t] atomic xenon transitions for gas temperatures/Xe, He/Ar/Xe, and Ne/Ar/Xe gas mixtures at a pump power of 8 W/cm3. For constant gas density, the gain

  3. Shell structure of potassium isotopes deduced from their magnetic moments

    E-Print Network [OSTI]

    J. Papuga; M. L. Bissell; K. Kreim; C. Barbieri; K. Blaum; M. De Rydt; T. Duguet; R. F. Garcia Ruiz; H. Heylen; M. Kowalska; R. Neugart; G. Neyens; W. Nortershauser; M. M. Rajabali; R. Sanchez; N. Smirnova; V. Soma; D. T. Yordanov

    2014-10-03

    \\item[Background] Ground-state spins and magnetic moments are sensitive to the nuclear wave function, thus they are powerful probes to study the nuclear structure of isotopes far from stability. \\item[Purpose] Extend our knowledge about the evolution of the $1/2^+$ and $3/2^+$ states for K isotopes beyond the $N = 28$ shell gap. \\item[Method] High-resolution collinear laser spectroscopy on bunched atomic beams. \\item[Results] From measured hyperfine structure spectra of K isotopes, nuclear spins and magnetic moments of the ground states were obtained for isotopes from $N = 19$ up to $N = 32$. In order to draw conclusions about the composition of the wave functions and the occupation of the levels, the experimental data were compared to shell-model calculations using SDPF-NR and SDPF-U effective interactions. In addition, a detailed discussion about the evolution of the gap between proton $1d_{3/2}$ and $2s_{1/2}$ in the shell model and {\\it{ab initio}} framework is also presented. \\item[Conclusions] The dominant component of the wave function for the odd-$A$ isotopes up to $^{45}$K is a $\\pi 1d_{3/2}^{-1}$ hole. For $^{47,49}$K, the main component originates from a $\\pi 2s_{1/2}^{-1}$ hole configuration and it inverts back to the $\\pi 1d_{3/2}^{-1}$ in $^{51}$K. For all even-$A$ isotopes, the dominant configuration arises from a $\\pi 1d_{3/2}^{-1}$ hole coupled to a neutron in the $\

  4. Allen County Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    3H ART 102 Drawing II 3 ART 127 Drawing 2 3 ART 103 Art Concepts and Practice 3 ART 120 Design 2-D 3 No equivalent Modern: 19th/20th/American/Photo 3 No equivalent East Asian 3 No equivalent Non Western: East to Philosophy 3 HUM 125 Philosophy 3 PHSX 211 General Physics 3 PSC 204 Engineering Physics 4 SOC 104 Elements

  5. Coffeyville Community College TRANSFER PROGRAM TO THE UNIVERSITY OF KANSAS

    E-Print Network [OSTI]

    ART 247 Drawing 2 3 ART 103 Art Concepts and Practice 3 ART 142 Design 2-D 3 ART 104 Art Principals No equivalent Modern: 19th/20th/American/Photo 3 No equivalent Non Western: East Asian/African 3 No equivalent/American Values 3 SOCI 201 American Social Problems 3 PHSX 114 College Physics 4 PHYS 203 College Physics I 5 PHSX

  6. Convex Drawings of Graphs in Two and Three Dimensions (Preliminary Version)

    E-Print Network [OSTI]

    Goodrich, Michael T.

    ], Steinitz 47], and Tutte 50, 51]. Our workaimsatcharacterizing the area/volume requirement of 2D/3D convex of drawings of n-vertex 3-connectedplanar graphs: 2D convex grid drawings with (3n) (3n=2) area under the edge L1-resolution rule; 2D strictly convex grid drawings with O(n 3) O(n 3) area under the edge

  7. E.LEWISSTREET GIRARD PARK CIRCLE

    E-Print Network [OSTI]

    Kearfott, R. Baker

    University Art Museum Joel L. Fletcher Hall Visual Arts Annex C.L. Rougeou Hall H.L. Griffin Hall Madison Rose Garden ndddolphl hl holph HHHa RSTREETTTT nnB anannauucBucha llHal n RoseeRR ardenardenGaGa. Griffin Hall D3 HH Hamilton Hall F7 JLF Joel L. Fletcher Hall E3 JUDI Judice-Rickels Hall D6 LEE Lee Hall

  8. lvlTH 140-Precalculus Oct. 16, 2014

    E-Print Network [OSTI]

    Hubbard, Keith

    lvlTH 140-Precalculus Exam 2 Name: _ Oct. 16, 2014 Directions: Answer the following questions in the space provided. Show all work for full credit. No calculators ma.y be used on this exam. (100 points-2.Si'2.- 3'f' 12. t 5Ji -2D ~3r2.. ' 3lf T ')1' (b) 4+ V2i 3 +5i (6) 2. Find the inverse function of f

  9. Using GIS and Spatial Modeling to Examine Active Travel Potential in a University Town

    E-Print Network [OSTI]

    Rybarczyk, Greg

    2014-11-19

    retention ? Universities are microcosms of society Greg Rybarczyk, Ph.D. 3 ?Universities and Active Transportation ? Benefits of increasing walking, bicycling, and mass transit utilization among a university population ? Reduce environmental externalities... ? Bicycle facilities ? Traffic Calming ? Programming ? City-wide partnerships ? Reducing parking demand ? Courses Greg Rybarczyk, Ph.D. 5 6Greg Rybarczyk, Ph.D. ?What about spatial and aspatial factors at the trip- origin? ? Neighborhood conditions ? Family...

  10. QED corrections to the 4p -4d transition energies of copperlike W. R. Johnson

    E-Print Network [OSTI]

    Johnson, Walter R.

    effects. For the 4p1/2 - 4d3/2 transition in copperlike bismuth, thorium and uranium, results are in good as the centrifugal barrier l(l + 1)/2r2 prevents them from getting too close to the nucleus, their contributions may and uranium [4]. With transition energies measured at 366.72(2), 491.94(10) and 535.15(5) eV, respectively

  11. USCOMM-WB-DC PRELIMZNARY REPORT OH HURRICANE DAISY

    E-Print Network [OSTI]

    QC 945.2 .D3 H8 1958 c.2 #12;#12;USCOMM-WB-DC #12;PRELIMZNARY REPORT OH HURRICANE DAISY AWGUST 24-29, 1958 Hurricane "Daisy", intense but small in area, was detected as a tropical storm about 300 miles into a hurricane on August 25. A u g u s t 27 it drifted very slowly northward. coast increased. the Atlantic off

  12. Ultra-broadband polarisers based on metastable free-standing aligned carbon nanotube membranes

    E-Print Network [OSTI]

    Cole, Matthew T.; Doherty, Matthew; Parmee, Richard; Dawson, Paul; Milne, William I.

    2014-07-24

    were nominally equivalent across the temperature range considered and were independently verified at room temperature using a Jandel four-probe 100 ?m contact stylus attached to a Keithley 2100. Alignment quantification: The degree of alignment... , is represented by; /2 4 /2 ( ) ( , )cosI k d ? ? ? ? ? ? ? ? ?? ?? ? ? ?? (3) where I( ? ) is the measured intensity, ? is the angle between the MWCNT axis and the incident polarised excitation, k is the maximum intensity at ? =0 and the function...

  13. The effects of deoxynivalenol on gene expression in the murine thymus

    SciTech Connect (OSTI)

    Kol, Sandra W.M. van; Hendriksen, Peter J.M.; Loveren, Henk van; Peijnenburg, Ad

    2011-02-01

    Deoxynivalenol (DON) is a mycotoxin produced by several Fusarium species and is often detected in grains. Because of its high abundance, there has been a large interest in the effects of DON in animals and humans. DON is known to be immunosuppressive at high concentrations and immunostimulatory at low concentrations. The present study aimed to acquire insight into the modes of action of DON. For this, C57Bl6 mice were orally exposed to 5, 10, or 25 mg/kg bw DON for 3, 6, or 24 h and thymuses were subjected to genome-wide expression microarray analysis. Gene set enrichment analysis (GSEA) demonstrated that DON downregulated genes involved in proliferation, mitochondria, protein synthesis, and ribosomal proteins. Furthermore, GSEA showed a selective downregulation of genes highly expressed at the early precursor thymocytes stage. This indicates that early precursor thymocytes, particularly at the double-positive CD4+CD8+ stage, are more vulnerable to DON than very early or late precursor thymocytes. There was a large overlap of genes upregulated by DON with genes previously reported to be either upregulated during T cell activation or upregulated during negative selection of thymocytes that recognize 'self-antigens'. This indicates that DON induces cellular events that also occur after activation of the T cell receptor, for example, release of calcium from the endoplasmatic reticulum. This T cell activation in the thymus then evokes negative selection and depletion of thymocytes, which provides a plausible explanation for the high sensitivity of the thymus for DON exposure. The expression patterns of four genes indicative for some of the processes that were affected after DON treatment were confirmed using real-time PCR. Immunocytological experiments with primary mouse thymocytes demonstrated the translocation of NFAT from the cytoplasm into the nucleus upon exposure top DON, thus providing further evidence for the involvement of T cell activation.

  14. ZFAT plays critical roles in peripheral T cell homeostasis and its T cell receptor-mediated response

    SciTech Connect (OSTI)

    Doi, Keiko; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka; Central Research Institute of Life Sciences for the Next Generation of Women Scientists, Fukuoka University, Fukuoka ; Fujimoto, Takahiro; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka ; Okamura, Tadashi; Ogawa, Masahiro; Tanaka, Yoko; Mototani, Yasumasa; Goto, Motohito; Ota, Takeharu; Matsuzaki, Hiroshi; Kuroki, Masahide; Tsunoda, Toshiyuki; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka ; Sasazuki, Takehiko; Shirasawa, Senji; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka

    2012-08-17

    Highlights: Black-Right-Pointing-Pointer We generated Cd4-Cre-mediated T cell-specific Zfat-deficient mice. Black-Right-Pointing-Pointer Zfat-deficiency leads to reduction in the number of the peripheral T cells. Black-Right-Pointing-Pointer Impaired T cell receptor-mediated response in Zfat-deficient peripheral T cells. Black-Right-Pointing-Pointer Decreased expression of IL-7R{alpha}, IL-2R{alpha} and IL-2 in Zfat-deficient peripheral T cells. Black-Right-Pointing-Pointer Zfat plays critical roles in peripheral T cell homeostasis. -- Abstract: ZFAT, originally identified as a candidate susceptibility gene for autoimmune thyroid disease, has been reported to be involved in apoptosis, development and primitive hematopoiesis. Zfat is highly expressed in T- and B-cells in the lymphoid tissues, however, its physiological function in the immune system remains totally unknown. Here, we generated the T cell-specific Zfat-deficient mice and demonstrated that Zfat-deficiency leads to a remarkable reduction in the number of the peripheral T cells. Intriguingly, a reduced expression of IL-7R{alpha} and the impaired responsiveness to IL-7 for the survival were observed in the Zfat-deficient T cells. Furthermore, a severe defect in proliferation and increased apoptosis in the Zfat-deficient T cells following T cell receptor (TCR) stimulation was observed with a reduced IL-2R{alpha} expression as well as a reduced IL-2 production. Thus, our findings reveal that Zfat is a critical regulator in peripheral T cell homeostasis and its TCR-mediated response.

  15. Inhibition of human peripheral blood lymphocyte function by protoporphyrin and longwave ultraviolet light

    SciTech Connect (OSTI)

    Barrett, K.E.; Yen, A.; Montisano, D.; Gigli, I.; Bigby, T.D.

    1994-10-01

    Modulation of immunologic effector cells by exogenous photoactive substances has been advanced as an underlying mechanism for the efficacy of various photochemotherapeutic regimens. It is also possible that endogenous photosensitizers, such as protoporphyrin, could similarly modify the function of immune cell types. The authors examined the effects of protoporphyrin plus longwave UV light on the ability of human PBL to proliferate in response to mitogens. Noncytotoxic dosages of protoporphyrin plus UV light suppressed PHA-stimulated proliferation of both PBMC and enriched T cells. CD8{sup +} cells were more sensitive to this inhibitory effect than CD4{sup +} cells. The inhibitory effect was also observed when proliferation was induced by the combination of a phorbol ester and ionomycin. Inhibition of PBMC proliferation was associated with inhibition of IL-2 secretion but proliferation was not restored with exogenous IL-2. Instead, the effect of protoporphyrin plus UV light may be on IL-2R. Cells treated with protoporphyrin and UV light did not display the increase in CD25 and {beta}-chain of the IL-2R induced by PHA in control cells. In contrast to the effects of protoporphyrin and UV light on IL-2 and IL-2R {alpha}-chain protein expression, the accumulation of mRNA for these proteins induced by PHA was unaffected. None of the effects of protoporphyrin plus UV light on lymphocytes were observed in control experiments where cells were treated with either protoporphyrin or UV light alone. They conclude that biologically relevant dosages of protoporphyrin and UV light modify the function of circulating lymphocytes. 26 refs., 8 figs., 1 tab.

  16. Generation of knock-in primary human T cells using Cas9 ribonucleoproteins

    SciTech Connect (OSTI)

    Schumann, Kathrin; Lin, Steven; Boyer, Eric; Simeonov, Dimitre R.; Subramaniam, Meena; Gate, Rachel E.; Haliburton, Genevieve E.; Ye, Chun J.; Bluestone, Jeffrey A.; Doudna, Jennifer A.; Marson, Alexander

    2015-07-27

    T-cell genome engineering holds great promise for cell-based therapies for cancer, HIV, primary immune deficiencies, and autoimmune diseases, but genetic manipulation of human T cells has been challenging. Improved tools are needed to efficiently “knock out” genes and “knock in” targeted genome modifications to modulate T-cell function and correct disease-associated mutations. CRISPR/Cas9 technology is facilitating genome engineering in many cell types, but in human T cells its efficiency has been limited and it has not yet proven useful for targeted nucleotide replacements. Here we report efficient genome engineering in human CD4+ T cells using Cas9:single-guide RNA ribonucleoproteins (Cas9 RNPs). Cas9 RNPs allowed ablation of CXCR4, a coreceptor for HIV entry. Cas9 RNP electroporation caused up to ~40% of cells to lose high-level cell-surface expression of CXCR4, and edited cells could be enriched by sorting based on low CXCR4 expression. Importantly, Cas9 RNPs paired with homology-directed repair template oligonucleotides generated a high frequency of targeted genome modifications in primary T cells. Targeted nucleotide replacement was achieved in CXCR4 and PD-1 (PDCD1), a regulator of T-cell exhaustion that is a validated target for tumor immunotherapy. Deep sequencing of a target site confirmed that Cas9 RNPs generated knock-in genome modifications with up to ~20% efficiency, which accounted for up to approximately one-third of total editing events. These results establish Cas9 RNP technology for diverse experimental and therapeutic genome engineering applications in primary human T cells.

  17. Generation of knock-in primary human T cells using Cas9 ribonucleoproteins

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Schumann, Kathrin; Lin, Steven; Boyer, Eric; Simeonov, Dimitre R.; Subramaniam, Meena; Gate, Rachel E.; Haliburton, Genevieve E.; Ye, Chun J.; Bluestone, Jeffrey A.; Doudna, Jennifer A.; et al

    2015-07-27

    T-cell genome engineering holds great promise for cell-based therapies for cancer, HIV, primary immune deficiencies, and autoimmune diseases, but genetic manipulation of human T cells has been challenging. Improved tools are needed to efficiently “knock out” genes and “knock in” targeted genome modifications to modulate T-cell function and correct disease-associated mutations. CRISPR/Cas9 technology is facilitating genome engineering in many cell types, but in human T cells its efficiency has been limited and it has not yet proven useful for targeted nucleotide replacements. Here we report efficient genome engineering in human CD4+ T cells using Cas9:single-guide RNA ribonucleoproteins (Cas9 RNPs). Cas9more »RNPs allowed ablation of CXCR4, a coreceptor for HIV entry. Cas9 RNP electroporation caused up to ~40% of cells to lose high-level cell-surface expression of CXCR4, and edited cells could be enriched by sorting based on low CXCR4 expression. Importantly, Cas9 RNPs paired with homology-directed repair template oligonucleotides generated a high frequency of targeted genome modifications in primary T cells. Targeted nucleotide replacement was achieved in CXCR4 and PD-1 (PDCD1), a regulator of T-cell exhaustion that is a validated target for tumor immunotherapy. Deep sequencing of a target site confirmed that Cas9 RNPs generated knock-in genome modifications with up to ~20% efficiency, which accounted for up to approximately one-third of total editing events. These results establish Cas9 RNP technology for diverse experimental and therapeutic genome engineering applications in primary human T cells.« less

  18. Molecular basis of the structural stability of a Top7-based scaffold at extreme pH and temperature conditions

    SciTech Connect (OSTI)

    Soares, Thereza A.; Boschek, Curt B.; Apiyo, David O.; Baird, Cheryl L.; Straatsma, TP

    2010-07-01

    The development of stable scaffolds that can tolerate environmental extremes has an immense potential for applications in industry and defense. Recently, we have engineered an eight-residue loop into the de novo designed Top7 protein, which specifically binds the glycoprotein CD4. The robust properties of the Top7, coupled with the ease in production, make it a robust scaffold to design novel functionalities for use under extreme environmental conditions. In the present work, a series of explicit-solvent molecular dynamics simulations are reported which investigates the effect of mutations and extreme conditions of temperature and pH on the structure, stability, and dynamics of the native and engineered Top7. These simulations indicate that i. The structural dynamics of the engineered and native Top7 in solution are equivalent under corresponding conditions of pH and temperature. Ensemble-averaged structures of the native and engineered Top7 maintain the overall tertiary structure pattern, albeit with loss of helical content when at low pH and high-temperature conditions. Mutations of residues E43A, D46A, E67A, E69A, EA81A along the ?-helices of the engineered Top7 did not lead to significant changes in the native fold under pH 2 and 400 K, suggesting that the helices can accommodate varying sequences. iii. The anti-parallel ?-sheet is the structural core responsible for the stability of the native and engineered Top7 and is well maintained under extreme pH and temperature conditions. These findings indicate that the insertion of an eight-residue loop into the structure of Top7 does not adversely affect the global fold or the structural stability of the Top7 scaffold.

  19. 3D PIC simulations of electron beams created via reflection of intense laser light from a water target

    E-Print Network [OSTI]

    Ngirmang, Gregory K; Feister, Scott; Morrison, John T; Chowdhury, Enam A; Frische, Kyle; Roquemore, W M

    2015-01-01

    We present 3D Particle-in-Cell (PIC) modeling of an ultra-intense laser experiment by the Extreme Light group at the Air Force Research Laboratory (AFRL) using the PIC code LSP. This is the first time PIC simulations have been performed in 3D for this experiment which involves an ultra-intense, short-pulse (30 fs) laser interacting with a water jet target at normal incidence. These 3D PIC simulation results are compared to results from 2D(3$v$) PIC simulations for both $5.4\\cdot10^{17}$ W cm$^{-2}$ and $3\\cdot10^{18}$ W cm$^{-2}$ intensities. Comparing the 2D(3$v$) and 3D simulation results, the laser-energy-to-ejected-electron-energy conversion efficiencies were comparable, but the angular distribution of ejected electrons show interesting differences with qualitative differences at higher intensity. An analytic plane-wave model is provided that provides some explanation for the angular distribution and energies of ejected electrons in the 2D(3$v$) simulations. We also performed a 3D simulation with circular...

  20. Deuteration in infrared dark clouds

    E-Print Network [OSTI]

    Lackington, Matias; Pineda, Jaime E; Garay, Guido; Peretto, Nicolas; Traficante, Alessio

    2015-01-01

    Much of the dense gas in molecular clouds has a filamentary structure but the detailed structure and evolution of this gas is poorly known. We have observed 54 cores in infrared dark clouds (IRDCs) using N$_2$H$^+$ (1-0) and (3-2) to determine the kinematics of the densest material, where stars will form. We also observed N$_2$D$^+$ (3-2) towards 29 of the brightest peaks to analyse the level of deuteration which is an excellent probe of the quiescent of the early stages of star formation. There were 13 detections of N$_2$D$^+$ (3-2). This is one of the largest samples of IRDCs yet observed in these species. The deuteration ratio in these sources ranges between 0.003 and 0.14. For most of the sources the material traced by N$_2$D$^+$ and N$_2$H$^+$ (3-2) still has significant turbulent motions, however three objects show subthermal N$_2$D$^+$ velocity dispersion. Surprisingly the presence or absence of an embedded 70 $\\mu$m source shows no correlation with the detection of N$_2$D$^+$ (3-2), nor does it correl...

  1. The Crystal Structure of Escherichia coli Group 4 Capsule Protein GfcC Reveals a Domain Organization Resembling That of Wza

    SciTech Connect (OSTI)

    Sathiyamoorthy, Karthik; Mills, Erez; Franzmann, Titus M.; Rosenshine, Ilan; Saper, Mark A. (Michigan); (Hebrew)

    2012-03-15

    We report the 1.9 {angstrom} resolution crystal structure of enteropathogenic Escherichia coli GfcC, a periplasmic protein encoded by the gfc operon, which is essential for assembly of group 4 polysaccharide capsule (O-antigen capsule). Presumed gene orthologs of gfcC are present in capsule-encoding regions of at least 29 genera of Gram-negative bacteria. GfcC, a member of the DUF1017 family, is comprised of tandem {beta}-grasp (ubiquitin-like) domains (D2 and D3) and a carboxyl-terminal amphipathic helix, a domain arrangement reminiscent of that of Wza that forms an exit pore for group 1 capsule export. Unlike the membrane-spanning C-terminal helix from Wza, the GfcC C-terminal helix packs against D3. Previously unobserved in a {beta}-grasp domain structure is a 48-residue helical hairpin insert in D2 that binds to D3, constraining its position and sequestering the carboxyl-terminal amphipathic helix. A centrally located and invariant Arg115 not only is essential for proper localization but also forms one of two mostly conserved pockets. Finally, we draw analogies between a GfcC protein fused to an outer membrane {beta}-barrel pore in some species and fusion proteins necessary for secreting biofilm-forming exopolysaccharides.

  2. Density-functional approaches to non-bonding interactions: a comparison of dispersion corrections (DFT-D), exchange-hole dipole moment (XDM) theory, and specialized functionals

    SciTech Connect (OSTI)

    Burns, Lori A [ORNL; Sherrill, David [Georgia Institute of Technology; Vazquez-Mayagoitia, Alvaro [ORNL; Sumpter, Bobby G [ORNL

    2011-01-01

    A systematic study of techniques for treating non-covalent interactions within the computationally efficient density functional theory (DFT) framework is presented through comparison to benchmark-quality evaluations of binding strength com- piled for molecular complexes of diverse size and nature. In particular, the effi- cacy of functionals deliberately crafted to encompass long-range forces, a posteri- ori DFT+dispersion corrections (DFT-D2 and DFT-D3), and exchange-hole dipole moment (XDM) theory is assessed against a large collection (469 energy points) of reference interaction energies at the CCSD(T) level of theory extrapolated to the estimated complete basis set limit. The established S22 and JSCH test sets of minimum-energy structures, as well as collections of dispersion-bound (NBC10) and hydrogen-bonded (HBC6) dissociation curves and a pairwise decomposition of a protein-ligand reaction site (HSG), comprise the chemical systems for this work. From evaluations of accuracy, consistency, and efficiency for PBE-D, BP86-D, B97-D, PBE0-D, B3LYP-D, B970-D, M05-2X, M06-2X, B97X-D, B2PLYP-D, XYG3, and B3LYP-XDM methodologies, it is concluded that distinct, often contrasting, groups of these elicit the best performance within the accessible double- or robust triple- basis set regimes and among hydrogen-bonded or dispersion-dominated complexes. For overall results, M05-2X, B97-D3, and B970-D2 yield superior values in conjunc- tion with aug-cc-pVDZ, for a mean absolute deviation of 0.41 0.49 kcal/mol, and B3LYP-D3, B97-D3, B97X-D, and B2PLYP-D3 dominate with aug-cc-pVTZ, af- fording, together with XYG3/6-311+G(3df,2p), a mean absolute deviation of 0.33 0.38 kcal/mol.

  3. The effect of shock dynamics on compressibility of ignition-scale National Ignition Facility implosions

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zylstra, A. B.; Frenje, J. A.; Seguin, F. H.; Hicks, D. G.; Dewald, E. L.; Robey, H. F.; Rygg, J. R.; Meezan, N. B.; Rosenberg, M. J.; Rinderknecht, H. G.; Friedrich, S.; Bionta, R.; Olson, R.; Atherton, J.; Barrios, M.; Bell, P.; Benedetti, R.; Berzak Hopkins, L.; Betti, R.; Bradley, D.; Callahan, D.; Casey, D.; Collins, G.; Dixit, S.; Doppner, T.; Edgell, D.; Edwards, M. J.; Gatu Johnson, M.; Glenn, S.; Glenzer, S.; Grim, G.; Hatchett, S.; Jones, O.; Khan, S.; Kilkenny, J.; Kline, J.; Knauer, J.; Kritcher, A.; Kyrala, G.; Landen, O.; LePape, S.; Li, C. K.; Lindl, J.; Ma, T.; Mackinnon, A.; Macphee, A.; Manuel, M. J.-E.; Meyerhofer, D.; Moody, J.; Moses, E.; Nagel, S.R.; Nikroo, A.; Pak, A.; Parham, T.; Petrasso, R. D.; Prasad, R.; Ralph, J.; Rosen, M.; Ross, J. S.; Sangster, T. C.; Sepke, S.; Sinenian, N.; Sio, H. W.; Spears, B.; Springer, P.; Tommasini, R.; Town, R.; Weber, S.; Wilson, D.; Zacharias, R.

    2014-11-01

    The effects of shock dynamics on compressibility of indirect-drive ignition-scale surrogate implosions, CH shells filled with D3He gas, have been studied using charged-particle spectroscopy. Spectral measurements of D3He protons produced at the shock-bang time probe the shock dynamics and in-flight characteristics of an implosion. The proton shock yield is found to vary by over an order of magnitude. A simple model relates the observed yield to incipient hot-spot adiabat, suggesting that implosions with rapid radiation-power increase during the main drive pulse may have a 2! higher hot-spot adiabat, potentially reducing compressibility. A self-consistent 1-D implosion model was used to infer the areal density (pR) and the shell center-of-mass radius (Rcm) from the downshift of the shock-produced D3He protons. The observed pR at shock-bang time is substantially higher for implosions, where the laser drive is on until near the compression bang time ('short-coast'), while longer-coasting implosions have lower pR. This corresponds to a much larger temporal difference between the shock- and compression-bang time in the long-coast implosions (~800 ps) than in the short-coast (~400 ps); this will be verified with a future direct bang-time diagnostic. This model-inferred differential bang time contradicts radiation-hydrodynamic simulations, which predict constant 700–800 ps differential independent of coasting time; this result is potentially explained by uncertainties in modeling late-time ablation drive on the capsule. In an ignition experiment, an earlier shock-bang time resulting in an earlier onset of shell deceleration, potentially reducing compression and, thus, fuel pR.

  4. The effect of shock dynamics on compressibility of ignition-scale National Ignition Facility implosions

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zylstra, A. B.; Frenje, J. A.; Séguin, F. H.; Hicks, D. G.; Dewald, E. L.; Robey, H. F.; Rygg, J. R.; Meezan, N. B.; Rosenberg, M. J.; Rinderknecht, H. G.; et al

    2014-11-03

    The effects of shock dynamics on compressibility of indirect-drive ignition-scale surrogate implosions, CH shells filled with D3He gas, have been studied using charged-particle spectroscopy. Spectral measurements of D3He protons produced at the shock-bang time probe the shock dynamics and in-flight characteristics of an implosion. The proton shock yield is found to vary by over an order of magnitude. A simple model relates the observed yield to incipient hot-spot adiabat, suggesting that implosions with rapid radiation-power increase during the main drive pulse may have a 2x higher hot-spot adiabat, potentially reducing compressibility. A self-consistent 1-D implosion model was used to infermore »the areal density (pR) and the shell center-of-mass radius (Rcm) from the downshift of the shock-produced D3He protons. The observed pR at shock-bang time is substantially higher for implosions, where the laser drive is on until near the compression bang time ('short-coast'), while longer-coasting implosions have lower pR. This corresponds to a much larger temporal difference between the shock- and compression-bang time in the long-coast implosions (~800 ps) than in the short-coast (~400 ps); this will be verified with a future direct bang-time diagnostic. This model-inferred differential bang time contradicts radiation-hydrodynamic simulations, which predict constant 700–800 ps differential independent of coasting time. This result is potentially explained by uncertainties in modeling late-time ablation drive on the capsule. In an ignition experiment, an earlier shock-bang time resulting in an earlier onset of shell deceleration, potentially reducing compression and, thus, fuel pR.« less

  5. Topological evolution and photoluminescent properties of a series of divalent zinc-based metal–organic frameworks tuned via ancillary ligating spacers

    SciTech Connect (OSTI)

    Lian, Xiao-Min; Zhao, Wen; Zhao, Xiao-Li

    2013-04-15

    The combination of divalent zinc ions, 4-(4-carboxybenzamido)benzoic acid and exo-bidendate bipyridine ligands gave rise to a series of new MOFs: [ZnL(bipy)]·DMF·H{sub 2}O (1), [ZnL(bpe)]·1.5H{sub 2}O (2), [ZnL(bpa)]·4H{sub 2}O (3) and [ZnL(bpp)]·1.75H{sub 2}O (4) (MOF=metal-organic framework, bipy=4,4?-bipyridine, bpe=trans-1,2-bis(4-pyridyl)ethylene, bpa=1,2-bis(4-pyridinyl)ethane, bpp=1,3-bis(4-pyridinyl)propane, H{sub 2}L=4,4?-(carbonylimino)dibenzoic acid). Fine tune over the topology of the MOFs was achieved via systematically varying the geometric length of the second ligating bipyridine ligands. Single-crystal X-ray analysis reveals that complex 1 has a triply interpenetrated three-dimensional (3D) framework with elongated primitive cubic topology, whereas isostructural complexes 2 and 3 each possesses a 6-fold interpenetrated diamondiod 3D framework. Further expansion of the length of the bipyridine ligand to bpp leads to the formation of 4, which features an interesting entangled architecture of 2D?3D parallel polycatenation. In addition, the thermogravimetric analyses and solid-state photoluminescent properties of the selected complexes are investigated. - Graphical abstract: The incorporation of exo-bidendate bipyridine spacers into the Zn–H{sub 2}L system has yielded a series of new MOFs exhibiting topological evolution from 3-fold interpenetration to 6-fold interpenetration and 2D?3D parallel polycatenation. Highlights: ? The effect of the pyridyl-based spacers on the formation of MOFs was explored. ? Fine tune over the topology of the MOFs was achieved. ? An interesting structure of 2D?3D parallel polycatenation is reported.

  6. Electric-Magnetic Dualities in Gauge Theories

    E-Print Network [OSTI]

    Jun-Kai Ho; Chen-Te Ma

    2015-07-28

    Electric-magnetic dualities are equivalence between strong and weak coupling constants. A standard way is to exchange electric and magnetic fields in the abelian gauge theory. We use three ways to perform electric-magnetic dualities in the case of the non-commutative $U(1)$ gauge theory. The first way is to use covariant field strengths to be the electric and magnetic fields. We find an invariant form of the equation of motion after performing the electric-magnetic duality. The second way is to use the Seiberg-Witten map to rewrite the non-commutative $U(1)$ gauge theory in terms of abelian field strength. The third way is that we use the large Neveu Schwarz-Neveu Schwarz (NS-NS) background limit (non-commutativity parameter only has one degree of freedom) to consider the non-commutative $U(1)$ gauge theory or D3-brane. In this limit, we introduce or dualize a new one-form gauge potential to get a D3-brane in a large Ramond-Ramond (R-R) background via field redefinition. We also use perturbation to study equivalence between two D3-brane theories. Comparison on three methods in the non-commutative $U(1)$ gauge theory gives different physical implications. This comparison reflects differences between the non-abelian and non-commutative gauge theories in the electric-magnetic dualities. For a complete study, we also extend our studies to the simplest abelian and non-abelian $p$-form gauge theories, and a non-commutative theory with the non-abelian structure.

  7. Enhancement of $B(E2)$ and low excitation of the second 0$^+$ state near N=40 in Ge isotopes

    E-Print Network [OSTI]

    M. Hasegawa; T. Mizusaki; K. Kaneko; Y. Sun

    2007-02-23

    The long-standing problem of dramatic structure change near N=40 in Ge isotopes is investigated by means of large-scale shell model calculation. The analysis of simulated calculations suggests a possible understanding of the problem in terms of rapid increase in the $g_{9/2}$ proton and neutron occupation. The observed variation in excitation of the second $0^+$ state in $^{70,72,74}$Ge appears to correlate closely with the $g_{9/2}$ occupations induced by strong proton-neutron interactions. The enhancement of the $g_{9/2}$ occupancies is probably due to correlations in the $1g2d3s$ shell.

  8. Additive renormalization of the specific heat of O(n) symmetric systems in three-loop order

    E-Print Network [OSTI]

    Stuart S. C. Burnett

    1997-10-29

    We present three-loop formulas for the additive renormalization constant A(u,epsilon) and associated renormalization group function B(u) for the specific heat of the O(n) symmetric phi^4 model. Using this result, we obtain also the amplitude function above Tc within the minimally renormalied theory at fixed d=3. At the fixed point, the three-loop correction to B(u) turns out to be small (about 3% for n=2). We note that a correction of this size may become important at the level of accuracy expected in future experiments.

  9. Specific heat amplitude ratios for anisotropic Lifshitz critical behaviors

    E-Print Network [OSTI]

    Marcelo M. Leite

    2003-04-03

    We determine the specific heat amplitude ratio near a $m$-axial Lifshitz point and show its universal character. Using a recent renormalization group picture along with new field-theoretical $\\epsilon_{L}$-expansion techniques, we established this amplitude ratio at one-loop order. We estimate the numerical value of this amplitude ratio for $m=1$ and $d=3$. The result is in very good agreement with its experimental measurement on the magnetic material $MnP$. It is shown that in the limit $m \\to 0$ it trivially reduces to the Ising-like amplitude ratio.

  10. A geometric level set model for ultrasounds analysis

    SciTech Connect (OSTI)

    Sarti, A.; Malladi, R.

    1999-10-01

    We propose a partial differential equation (PDE) for filtering and segmentation of echocardiographic images based on a geometric-driven scheme. The method allows edge-preserving image smoothing and a semi-automatic segmentation of the heart chambers, that regularizes the shapes and improves edge fidelity especially in presence of distinct gaps in the edge map as is common in ultrasound imagery. A numerical scheme for solving the proposed PDE is borrowed from level set methods. Results on human in vivo acquired 2D, 2D+time,3D, 3D+time echocardiographic images are shown.

  11. Dissociable rate dependent effects of oral methylphenidate on impulsivity and D2/3 receptor availability in the striatum

    E-Print Network [OSTI]

    Caprioli, Daniele; Jupp, Bianca; Hong, Young T.; Sawiak, Stephen J.; Ferrari, Valentina; Wharton, Laura; Williamson, David J; McNabb, Carolyn; Berry, David; Aigbirhio, Franklin I.; Robbins, Trevor W.; Fryer, Tim D.; Dalley, Jeffrey W.

    2015-03-04

    added per litre. The gradient run was 20%-100% 181 mobile phase B over 10 minutes. Positive MRM was used to monitor the chromatography column 182 eluent [MPH (MRM 234-84), ritalinic acid (MRM 220-84) and d3-MPH (MRM 237-84)]. The LLOD was 183 0.008 mg... . (2007) Consensus nomenclature for in vivo imaging of reversibly binding 525 radioligands. Journal of cerebral blood flow and metabolism : official journal of the 526 International Society of Cerebral Blood Flow and Metabolism 27:1533-1539. 527 Jupp B...

  12. Density functional theory of freezing for hexagonal symmetry: Comparison with Landau theory

    E-Print Network [OSTI]

    Laird, Brian Bostian; McCoy, John D.; Haymet, A. D. J.

    1988-01-01

    to the symmetry constraints of the crystal lattice under investigation. In paper I we corrected inconsistencies in ear­ lier versions of the Fourier expansion method, and examined carefully the freezing of the hard sphere and Lennard-Jones liquids into face...) to the triangular lattice, and in three dimensions (d = 3) to the hexagonally close-packed (hcp) lattice. The freezing of hard spheres into the hcp structure has been examined previously, by YuSSOUffl5 and by Igloil6 using the Fourier method, and by Baus...

  13. Enhanced fault-tolerant quantum computing in $d$-level systems

    E-Print Network [OSTI]

    Earl T. Campbell

    2014-06-11

    Error correcting codes protect quantum information and form the basis of fault tolerant quantum computing. Leading proposals for fault-tolerant quantum computation require codes with an exceedingly rare property, a transverse non-Clifford gate. Codes with the desired property are presented for $d$-level, qudit, systems with prime $d$. The codes use $n=d-1$ qudits and can detect upto $\\sim d/3$ errors. We quantify the performance of these codes for one approach to quantum computation, known as magic state distillation. Unlike prior work, we find performance is always enhanced by increasing $d$.

  14. Chemical Potential in the Gravity Dual of a 2+1 Dimensional System

    E-Print Network [OSTI]

    Nick Evans; Ed Threlfall

    2009-02-16

    We study probe D5 branes in D3 brane AdS_5 and AdS_5-Schwarzschild backgrounds as a prototype dual description of strongly coupled 2+1 dimensional quasi-particles. We introduce a chemical potential through the U(1)_R symmetry group, U(1) baryon number and a U(1) of isospin in the multi-flavour case. We find the appropriate D5 embeddings in each case - the embeddings do not exhibit the spontaneous symmetry breaking that would be needed for a superconductor. The isospin chemical potential does induce the condensation of charged meson states.

  15. A Fully-Integrated 5GHz CMOS Wireless-LAN Receiver

    E-Print Network [OSTI]

    Lee, Thomas H.

    ( ) ------------------ fmin fmax #12;Parasitic capacitance Cx degrades the noise performance. Noise Rejection In M3 M1 X Cx Lx;Equivalent Noise Circuit for the LNA M1 X Cx Zin Ls Lg M3 Iout + - + - V s 2 V g1 2 I g1 2 I d3 2 Rs Rin1 Cx drain noise modeled) #12;Filter Noise Model I d5 2 I L5 2 C3 C1Cx L5 1 gm5 ----------­ I d5 2 I L5 2

  16. The Flux-Scaling Scenario: De Sitter Uplift and Axion Inflation

    E-Print Network [OSTI]

    Blumenhagen, Ralph; Font, Anamaria; Herschmann, Daniela; Sun, Rui

    2015-01-01

    Non-geometric flux-scaling vacua provide promising starting points to realize axion monodromy inflation via the F-term scalar potential. We show that these vacua can be uplifted to Minkowski and de Sitter by adding an anti D3-brane or a D-term containing geometric and non-geometric fluxes. These uplifted non-supersymmetric models are analyzed with respect to their potential to realize axion monodromy inflation self-consistently. Admitting rational values of the fluxes, we construct examples with the required hierarchy of mass scales.

  17. The Flux-Scaling Scenario: De Sitter Uplift and Axion Inflation

    E-Print Network [OSTI]

    Ralph Blumenhagen; Cesar Damian; Anamaria Font; Daniela Herschmann; Rui Sun

    2015-10-06

    Non-geometric flux-scaling vacua provide promising starting points to realize axion monodromy inflation via the F-term scalar potential. We show that these vacua can be uplifted to Minkowski and de Sitter by adding an anti D3-brane or a D-term containing geometric and non-geometric fluxes. These uplifted non-supersymmetric models are analyzed with respect to their potential to realize axion monodromy inflation self-consistently. Admitting rational values of the fluxes, we construct examples with the required hierarchy of mass scales.

  18. Stable blowup for wave equations in odd space dimensions

    E-Print Network [OSTI]

    Roland Donninger; Birgit Schörkhuber

    2015-04-03

    We consider semilinear wave equations with focusing power nonlinearities in odd space dimensions $d \\geq 5$. We prove that for every $p > \\frac{d+3}{d-1}$ there exists an open set of radial initial data in $H^{\\frac{d+1}{2}} \\times H^{\\frac{d-1}{2}}$ such that the corresponding solution exists in a backward lightcone and approaches the ODE blowup profile. The result covers the entire range of energy supercritical nonlinearities and extends our previous work for the three-dimensional radial wave equation to higher space dimensions.

  19. Scaling Up Reinforcement Learning without Sacrificing Optimality by Constraining Exploration 

    E-Print Network [OSTI]

    Mann, Timothy 1984-

    2012-12-05

    . . . . . . . . 160 7.9 Comparison between the cumulative reward earned by LET and MTQL in D1, D2, D3, and D4 extended to 10 actions rather than 4. Whiskers indicate 1.5 times the interquartile range. . . . . . . . . . . . . . . . . 161 7.10 The number of entries... in the Distributed Computing Group. David?s mentor- ship helped me to gain con dence and skills that were critical for success in graduate school. During my time as a PhD student, I was fortunate to have the opportunity to work on a research project...

  20. Investigations of the distribution of the most significant F-ratio 

    E-Print Network [OSTI]

    Radhakumari, Bodapati Venkata

    1967-01-01

    2 s based on m degrees of freedom. It is well known that, if' in fact there are no real treatment effects and all treatment mean squares are tested by the ordinary F-test at the 100a percent level of sig- nificance, the risk of returning at least... of freedom to an independent 2 error mean square (s ) based on m degrees of freedom when t. =t = l. 1 2 Finney obtained the probability distribution for the above ratio as (I+I) L= 0 (-aD 1 ( m-1 -u where N = 1-L, D = 3 , L =~ u e du =I' (m) = r~m& -a...