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We encourage you to perform a real-time search of NLEBeta
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1

Biological Systems Science Division (BSSD) | U.S. DOE Office of Science  

Office of Science (SC) Website

Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Structural Biology DOE Joint Genome Institute Climate and Environmental Sciences Division (CESD) Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301)

2

Genomic Science | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Biological Systems Science Division (BSSD) » Genomic Science Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Structural Biology DOE Joint Genome Institute Climate and Environmental Sciences Division (CESD) Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building

3

DOE Joint Genome Institute | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

DOE Joint Genome Institute DOE Joint Genome Institute Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Structural Biology DOE Joint Genome Institute Climate and Environmental Sciences Division (CESD) Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301)

4

Genome Science/Technologies  

NLE Websites -- All DOE Office Websites (Extended Search)

Science & Innovation » Science & Innovation » Science & Engineering Capabilities » Bioscience: Bioenergy, Biosecurity, and Health » Environmental Microbiology » Genome Genome Science/Technologies Los Alamos using cutting-edge sequencing, finishing, and analysis, impact valuable genomic data. Get Expertise Cheryl Kuske DOE BER Biological System Science Division Program Manager Email Srinivas Iyer Bioscience Group Leader Email Momchilo Vuyisich Bioenergy and Biomedical Sciences Email Rebecca McDonald Bioscience Communications Email State-of-the art technology and extensive genomics expertise Protein research Read caption + Los Alamos National Laboratory graduate student, Patricia Langan, changes the properties of a green fluorescent protein in order to create new fluorescent protein variants.

5

Genome Science/Technologies  

NLE Websites -- All DOE Office Websites (Extended Search)

Momchilo Vuyisich Bioenergy and Biomedical Sciences Email Rebecca McDonald Bioscience Communications Email State-of-the art technology and extensive genomics expertise Protein...

6

Structural Biology | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Structural Biology Structural Biology Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Structural Biology DOE Joint Genome Institute Climate and Environmental Sciences Division (CESD) Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301)

7

Life Sciences & Genomics Division Diversity  

NLE Websites -- All DOE Office Websites (Extended Search)

Sciences & Genomics Diversity imagemap Workforce Diversity Action Plans title Diversity Committee Employment Opportunities Community Outreach Activities htmlempopps.html Read...

8

Low Dose Radiation | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Radiobiology: Low Dose Radiation Radiobiology: Low Dose Radiation Research Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Structural Biology DOE Joint Genome Institute Climate and Environmental Sciences Division (CESD) Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301)

9

Radiochemistry & Imaging Instrumentation | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Radiochemistry & Imaging Instrumentation Radiochemistry & Imaging Instrumentation Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Structural Biology DOE Joint Genome Institute Climate and Environmental Sciences Division (CESD) Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301)

10

Genomic Science Program Systems Biology for Energy and Environment  

NLE Websites -- All DOE Office Websites (Extended Search)

Major KBase Public Release Now Available 0213 More News and Announcements Reports DOE JGI Strategic Planning for the Genomic Sciences: Workshop Report 912 Plants and...

11

Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum  

E-Print Network (OSTI)

Page Incorporating Genomics and Bioinformatics across the2007) Discovering Genomics, Proteomics, and Bioinformatics,2003) Public access for teaching genomics, proteomics, and

Ditty, Jayna L.

2012-01-01T23:59:59.000Z

12

Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum  

Science Conference Proceedings (OSTI)

Undergraduate life sciences education needs an overhaul, as clearly described in the National Research Council of the National Academies publication BIO 2010: Transforming Undergraduate Education for Future Research Biologists. Among BIO 2010's top recommendations is the need to involve students in working with real data and tools that reflect the nature of life sciences research in the 21st century. Education research studies support the importance of utilizing primary literature, designing and implementing experiments, and analyzing results in the context of a bona fide scientific question in cultivating the analytical skills necessary to become a scientist. Incorporating these basic scientific methodologies in undergraduate education leads to increased undergraduate and post-graduate retention in the sciences. Toward this end, many undergraduate teaching organizations offer training and suggestions for faculty to update and improve their teaching approaches to help students learn as scientists, through design and discovery (e.g., Council of Undergraduate Research [www.cur.org] and Project Kaleidoscope [www.pkal.org]). With the advent of genome sequencing and bioinformatics, many scientists now formulate biological questions and interpret research results in the context of genomic information. Just as the use of bioinformatic tools and databases changed the way scientists investigate problems, it must change how scientists teach to create new opportunities for students to gain experiences reflecting the influence of genomics, proteomics, and bioinformatics on modern life sciences research. Educators have responded by incorporating bioinformatics into diverse life science curricula. While these published exercises in, and guidelines for, bioinformatics curricula are helpful and inspirational, faculty new to the area of bioinformatics inevitably need training in the theoretical underpinnings of the algorithms. Moreover, effectively integrating bioinformatics into courses or independent research projects requires infrastructure for organizing and assessing student work. Here, we present a new platform for faculty to keep current with the rapidly changing field of bioinformatics, the Integrated Microbial Genomes Annotation Collaboration Toolkit (IMG-ACT). It was developed by instructors from both research-intensive and predominately undergraduate institutions in collaboration with the Department of Energy-Joint Genome Institute (DOE-JGI) as a means to innovate and update undergraduate education and faculty development. The IMG-ACT program provides a cadre of tools, including access to a clearinghouse of genome sequences, bioinformatics databases, data storage, instructor course management, and student notebooks for organizing the results of their bioinformatic investigations. In the process, IMG-ACT makes it feasible to provide undergraduate research opportunities to a greater number and diversity of students, in contrast to the traditional mentor-to-student apprenticeship model for undergraduate research, which can be too expensive and time-consuming to provide for every undergraduate. The IMG-ACT serves as the hub for the network of faculty and students that use the system for microbial genome analysis. Open access of the IMG-ACT infrastructure to participating schools ensures that all types of higher education institutions can utilize it. With the infrastructure in place, faculty can focus their efforts on the pedagogy of bioinformatics, involvement of students in research, and use of this tool for their own research agenda. What the original faculty members of the IMG-ACT development team present here is an overview of how the IMG-ACT program has affected our development in terms of teaching and research with the hopes that it will inspire more faculty to get involved.

Ditty, Jayna L.; Kvaal, Christopher A.; Goodner, Brad; Freyermuth, Sharyn K.; Bailey, Cheryl; Britton, Robert A.; Gordon, Stuart G.; Heinhorst, Sabine; Reed, Kelynne; Xu, Zhaohui; Sanders-Lorenz, Erin R.; Axen, Seth; Kim, Edwin; Johns, Mitrick; Scott, Kathleen; Kerfeld, Cheryl A.

2011-08-01T23:59:59.000Z

13

Data Management | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Data Management Data Management Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC)

14

Dr J Michael Kuperberg | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Climate and Climate and Environmental Sciences Division (CESD) » Dr J Michael Kuperberg Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities

15

ARM Climate Research Facility | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Research » Climate and Research » Climate and Environmental Sciences Division (CESD) » ARM Climate Research Facility Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER

16

William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) | U.S.  

NLE Websites -- All DOE Office Websites (Extended Search)

William R. Wiley Environmental William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC)

17

Atmospheric System Research (ASR) Program | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

» Atmospheric System Research (ASR) » Atmospheric System Research (ASR) Program Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC)

18

Integrated Assessment of Global Climate Change | U.S. DOE Office of Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Integrated Assessment of Global Integrated Assessment of Global Climate Change Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC)

19

Earth System Modeling (ESM) Program | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Earth System Modeling (ESM) Earth System Modeling (ESM) Program Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC)

20

Subsurface Biogeochemical Research | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Subsurface Biogeochemical Subsurface Biogeochemical Research Biological and Environmental Research (BER) BER Home About Research Research Abstracts Searchable Archive of BER Highlights External link Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change Regional & Global Climate Modeling (RGCM) Program Subsurface Biogeochemical Research Terrestrial Carbon Sequestration External link Terrestrial Ecosystem Science Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC)

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Science Highlights | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Science Highlights Science Highlights Biological and Environmental Research (BER) BER Home About Research Facilities Science Highlights Searchable Archive of BER Highlights External link Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301) 903-5051 E: sc.ber@science.doe.gov More Information » Science Highlights Print Text Size: A A A Subscribe FeedbackShare Page Filter within BER Or press Esc Key to close. close Select all that apply. Bioenergy Research Centers (BRCs) Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD)

22

Los Alamos National Laboratory: Bioscience Division: Genome Science...  

NLE Websites -- All DOE Office Websites (Extended Search)

areas. B-6 Teams Applications Bioinformatics Computational Finishing Project Management Sequencing Technology Focus on Research Links Resources Joint Genome Institute (JGI)...

23

Applications of Genome-based Science in Shaping the World's Citrus Industries (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)  

Science Conference Proceedings (OSTI)

Fred Gmitter from the University of Florida on "Applications of Genome-based Science in Shaping the Future of the World's Citrus Industries" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

Gmitter, Jr., Fred (University of Florida)

2012-03-21T23:59:59.000Z

24

Entrepreneurial experiments in science policy: Analyzing the Human Genome Project  

E-Print Network (OSTI)

We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments ...

Huang, Kenneth G.

25

DOE Joint Genome Institute: Tringe on Popular Science's "Brilliant 10"  

NLE Websites -- All DOE Office Websites (Extended Search)

6, 2011 6, 2011 Tringe on Popular Science's "Brilliant 10" List WALNUT CREEK, Calif.-Susannah Green Tringe of the DOE Joint Genome Institute (DOE JGI) has been named one of 2011's "Brilliant 10," the annual list compiled by Popular Science magazine of top young researchers. In adding her name to the list, which appears in the October issue, the magazine recognized her $2.5 million grant from the DOE Early Career Research Program to study the role of microbial communities in restored wetlands in the San Francisco Bay-Delta region of California and their impact on long-term carbon sequestration. Bigelow's Dashiell Masland working Photo: Tringe wading into the Brilliant 10 list The Popular Science Brilliant 10 recognizes scientists and researchers

26

First Annual U.S. Department of Energy Office of Science Joint Genome Institute User Meeting  

E-Print Network (OSTI)

relatives for genome sequencing (A. lyrata and CapsellaThis is our rationale for genome sequencing of a free-livingof de Novo Genome Sequencing with 454 Technology Stephen

Various

2006-01-01T23:59:59.000Z

27

Computational methods and analyses in comparative genomics and epigenomics  

E-Print Network (OSTI)

promise of comparative genomics in mammals. Science, 286,homology relationships. Genomics, Dehal, P. and Boore, J.to plant comparative genomics. Genome Research, 13(5), 999

Peng, Qian

2012-01-01T23:59:59.000Z

28

Genomic Advances to Improve Biomass for Biofuels (LBNL Science at the Theater)  

DOE Green Energy (OSTI)

Lawrence Berkeley National Lab bioscientist Daniel Rokhsar discusses genomic advances to improve biomass for biofuels. He presented his talk Feb. 11, 2008 in Berkeley, California as part of Berkeley Lab's community lecture series. Rokhsar works with the U.S. Department of Energy's Joint Genome Institute and Berkeley Lab's Genomics Division.

Rokhsar, Daniel

2008-02-11T23:59:59.000Z

29

Genome To Life Report | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Genome To Life Report Genome To Life Report Biological and Environmental Research Advisory Committee (BERAC) BERAC Home Meetings Members Charges/Reports Current BERAC Charges Archive of BERAC Reports Charter .pdf file (40KB) BER Committees of Visitors BER Home Charges/Reports Genome To Life Report Print Text Size: A A A RSS Feeds FeedbackShare Page DOE Genomes to Life Program Information External link BRINGING THE GENOME TO LIFE - Energy Related Biology in the New Genomic World - A New Research Program for the Department of Energy's Office of Biological and Environmental Research recommended by the Biological and Environmental Research Advisory Committee June 2000 In response to the charge letter of Dr. Martha Krebs, November 24, 1999 OVERVIEW Mission: To develop the capability of understanding and predicting the behavior of

30

DOE Joint Genome Institute: A DOE Office of Science User Facility of  

NLE Websites -- All DOE Office Websites

MyJGISubmit ProposalsInternalEmergency InfoCareers MyJGISubmit ProposalsInternalEmergency InfoCareers JGI website People Go Genomes Project List User Programs Sequencing Informatics Systems Education News & Publications Events About Us JGI Home DOE Joint Genome Institute Latest News R. irregularis December 20, 2013 A gluttonous plant reveals how its cellular power plant devours foreign DNA. Amborella trichopoda, a sprawling shrub that grows on just a single island in the remote South Pacific, is the only plant in its family and genus. It is also one of the oldest flowering plants, having branched off from others about 200 million years ago. more... R. irregularis November 25, 2013 How Scavenging Fungi Became a Plant's Best Friend. Glomeromycota is an ancient lineage of fungi that has a symbiotic relationship with roots that

31

DOE Joint Genome Institute: A DOE Office of Science User Facility of  

NLE Websites -- All DOE Office Websites (Extended Search)

DOE Joint Genome Institute DOE Joint Genome Institute Latest News R. irregularis December 20, 2013 A gluttonous plant reveals how its cellular power plant devours foreign DNA. Amborella trichopoda, a sprawling shrub that grows on just a single island in the remote South Pacific, is the only plant in its family and genus. It is also one of the oldest flowering plants, having branched off from others about 200 million years ago. more... R. irregularis November 25, 2013 How Scavenging Fungi Became a Plant's Best Friend. Glomeromycota is an ancient lineage of fungi that has a symbiotic relationship with roots that goes back nearly 420 million years to the earliest plants. More than two thirds of the world's plants depend on this soil-dwelling symbiotic fungus to survive, including critical agricultural crops such as wheat,

32

Science Videos from DOE's Joint Genome Institute on YouTube  

DOE Data Explorer (OSTI)

DOE's Joint Genome Institute began posting lab-produced videos on YouTube in September of 2008. Many of JGI's YouTube videos are of speakers' presentations at meetings and workshops; others may be promotional or educational in nature. They are freely available to the public for viewing and can be interactively shared or commented on. Users can subscribe and be notified when new videos are posted to their specific area of interest.

33

Tissue sampling and standards for vertebrate genomics  

E-Print Network (OSTI)

and standards for vertebrate genomics. GigaScience 2012 1:8.transition to conservation genomics. TIG 2010, 26:177187.Siemens DH: Ecological genomicschanging perspectives on

2012-01-01T23:59:59.000Z

34

Communicating Genomics:GTL  

NLE Websites -- All DOE Office Websites (Extended Search)

Annual Annual DOE Joint Genome Institute User Meeting Sponsored By U.S. Department of Energy Office of Science March 29-April 1, 2006 Embassy Suites Hotel and DOE Joint Genome Institute Walnut Creek, California iii Contents Agenda .................................................................................................................. iv Speaker Presentations . .........................................................................................1 Abtracts in order of presentation according to agenda (p. iv) Poster Presentations ..............................................................................................9 Posters alphabetical by first author. *Presenting author. Attendees...............................................................................................................75

35

DOE Joint Genome Institute: JGI's Susannah Tringe Receives Prestigious...  

NLE Websites -- All DOE Office Websites (Extended Search)

Energy (DOE) Office of Science Early Career Research Program has awarded a grant to DOE Joint Genome Institute scientist Susannah Green Tringe to conduct genomic studies of...

36

Genomics and Systems Biology  

NLE Websites -- All DOE Office Websites (Extended Search)

Genomics and Systems Biology Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work cover diverse fields such as energy, agriculture, and environmental cleanup. Get Expertise Babetta Marrone Biofuels Program Manager Email Cheryl Kuske DOE BER Biological System Science Division Program Manager Email Chris Detter Emerging Threats Program Manager: Email Rebecca McDonald Bioscience Communications Email "We were asked to build a rocket ship," said developer Joel Berendzen, "but instead we built a 10,000 mph motorcycle." - Sequedex team LANL leads the world in computational finishing of microbial genomes Protein research Read caption + In 2013, Los Alamos scientist Richard Sayre and his team genetically

37

Berkeley Lab Science Articles Archive  

NLE Websites -- All DOE Office Websites (Extended Search)

History of the Laboratory Human Genome & DNA Research Life Sciences Materials Sciences Medical & Risk-related Research Nuclear Science Physics Reports on Distinguished Lecturers...

38

Analyzing genomic data: understanding the genome  

Science Conference Proceedings (OSTI)

The effort that led to the sequencing of the human genome ushered life sciences into a new era. One of the largest international scientific endeavors of the time delivered the genetic makeup of our species to the research community. Further international ... Keywords: Algorithmic Development, Biological Data Mining, Data Mining Software Tools

Xos M. Fernndez-Surez

2012-03-01T23:59:59.000Z

39

Communicating Genomics:GTL  

NLE Websites -- All DOE Office Websites (Extended Search)

DOE Joint Genome Institute User Meeting Sponsored By U.S. Department of Energy Office of Science March 24-26, 2010 Walnut Creek Marriott Walnut Creek, California iii Contents Speaker Presentations ......................................................................................... 1 Poster Presentations........................................................................................... 11 Attendees............................................................................................................. 67 Author Index ...................................................................................................... 75 iv Posters alphabetical by first author. *Presenting author 1 Speaker Presentations Abstracts alphabetical by speaker

40

Genomic Aspects of Research Involving Polyploid Plants  

Science Conference Proceedings (OSTI)

Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Molluscan Evolutionary Genomics  

E-Print Network (OSTI)

59179 Molluscan Evolutionary Genomics W. Brian Simison andBoore Molluscan Evolutionary Genomics W. Brian Simison andL. Boore Evolutionary Genomics Department, DOE Joint Genome

Simison, W. Brian

2010-01-01T23:59:59.000Z

42

JGI - Structural Genomics Program  

NLE Websites -- All DOE Office Websites (Extended Search)

Structural Genomics Program Structural Genomics Program The structural characterization of proteins of unknown function can be described as structural genomics, an approach in which structure determination by X-ray crystallography supplies key functional information. This is exemplified by studies of the carboxysome. The structures of the first carboxysome shell proteins (Kerfeld et al., Science 2005) confirmed earlier hypotheses that they are indeed the basic building blocks of the carboxysome shell; the quaternary structure and the higher order assemblies of the proteins in the crystals provided insight into how they assemble into shell facets. Likewise, our structure of the carboxysome component CsoS3 revealed that it was a member of the beta-carbonic family, despite having no detectable sequence homology at the level of primary structure

43

Human Genome Program Image Gallery (from genomics.energy.gov)  

DOE Data Explorer (OSTI)

This collection contains approximately 240 images from the genome programs of DOE's Office of Science. The images are divided into galleries related to biofuels research, systems biology, and basic genomics. Each image has a title, a basic citation, and a credit or source. Most of the images are original graphics created by the Genome Management Information System (GMIS). GMIS images are recognizable by their credit line. Permission to use these graphics is not needed, but please credit the U.S. Department of Energy Genome Programs and provide the website http://genomics.energy.gov. Other images were provided by third parties and not created by the U.S. Department of Energy. Users must contact the person listed in the credit line before using those images. The high-resolution images can be downloaded.

44

Human Genome Research: Decoding DNA  

NLE Websites -- All DOE Office Websites (Extended Search)

Human Genome Research: Decoding DNA Human Genome Research: Decoding DNA Resources with Additional Information Charles DeLisi As head of DOE's Office of Health and Environmental Research, Charles DeLisi played a pivotal role in proposing and initiating the Human Genome Program in 1986. The U.S. Department of Energy (DOE) has historically been active in supporting human genome research. On September 10, 2003, Secretary of Energy Spencer Abraham presented the Secretary's Gold Award to Aristides Patrinos and Francis Collins for their leadership of the government's Human Genome Project. At DOE's Office of Science, Dr. Patrinos is the Associate Director for Biological and Environmental Research. He has been a researcher at the department's Oak Ridge National Laboratory and Brookhaven National Laboratory.

45

Genome Analyses and Supplement Data from the International Populus Genome Consortium (IPGC)  

DOE Data Explorer (OSTI)

The sequencing of the first tree genome, that of Populus, was a project initiated by the Office of Biological and Environmental Research in DOEs Office of Science. The International Populus Genome Consortium (IPGC) was formed to help develop and guide post-sequence activities. The IPGC website, hosted at the Oak Ridge National Laboratory, provides draft sequence data as it is made available from DOE Joint Genome Institute, genome analyses for Populus, lists of related publications and resources, and the science plan. The data are available at http://www.ornl.gov/sci/ipgc/ssr_resource.htm.

International Populus Genome Consortium (IPGC)

46

Genome resequencing reveals multiscale geographic structure and...  

NLE Websites -- All DOE Office Websites (Extended Search)

S, Bottolo L, Freeman C, McVean G, Donnelly P. 2005. A fine-scale map of recombination rates and hotspots across the human genome. Science 310: 321-324. Neale DB, Ingvarsson PK....

47

The comparative genomics of salinispora and the distribution and abundance of secondary metabolite genes in marine plankton  

E-Print Network (OSTI)

rplB smpB Comparative genomics Gene gain Gene loss Totalbiology and comparative genomics. BMC Bioinformatics 10(1):Intersection of Evolution and Genomics. Science 300(5626):

Penn, Kevin Matthew

2012-01-01T23:59:59.000Z

48

Molluscan Evolutionary Genomics  

E-Print Network (OSTI)

Todays high-throughput genome sequencing centers lack thecomplete nuclear genome sequencing, with several mollusksparticipation. The cost of genome sequencing is still very

Simison, W. Brian

2010-01-01T23:59:59.000Z

49

JGI Fungal Genomics Program  

E-Print Network (OSTI)

View Supports functional genomics, user data deposition andJGI Fungal Genomics Program Igor V. Grigoriev 1 DOE Jointof California. JGI Fungal Genomics Program Contact: Igor

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

50

JGI Fungal Genomics Program  

E-Print Network (OSTI)

JGI Fungal Genomics Program Igor V. Grigoriev 1 Lawrenceof California. JGI Fungal Genomics Program Contact: IgorJGI). Its key project, the Genomics Encyclopedia of Fungi,

Grigoriev, Igor V.

2012-01-01T23:59:59.000Z

51

Genomic Sciences | Clean Energy | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

research and communication resources at ORNL include the following: Plant Systems Biology Systems Genetics Metabolomics Plant-Microbe Interfaces Biological and Environmental...

52

Microbial Genomics  

NLE Websites -- All DOE Office Websites (Extended Search)

Teaching Tools Fun Facts Images Microbial Primer search Disclaimer Contact Us Awards Site Statistics The U.S. Department of Energy (DOE) Office of Science supports innovative,...

53

Using Partial Genomic Fosmid Libraries for Sequencing Complete Organellar Genomes  

E-Print Network (OSTI)

than total nuclear genome sequencing, making broaderavailable organellar genome sequencing methods, especiallyenables plastid genome sequencing from both parasitic and

McNeal, Joel R.; Leebens-Mack, James H.; Arumuganathan, K.; Kuehl, Jennifer V.; Boore, Jeffrey L.; dePamphilis, Claude W.

2005-01-01T23:59:59.000Z

54

DOE Joint Genome Institute: New Genomic Model Defines Microbes by  

NLE Websites -- All DOE Office Websites (Extended Search)

September 8, 2009 September 8, 2009 New Genomic Model Defines Microbes by Diet-Provides Tool for Tracking Environmental Change WALNUT CREEK, CA-In line with the U.S. Department of Energy (DOE) interest in characterizing the biotic factors involved in global carbon cycling, the DOE Joint Genome Institute (JGI) characterizes a diverse array of plants, microorganisms, and the communities in which they reside to inform options for reducing and stabilizing atmospheric greenhouse gases. Through a novel genomic approach detailed in the September 7 online edition and on the cover September 14 of the journal Proceedings of the National Academy of Sciences, an international team of scientists led by the University of New South Wales and the DOE JGI demonstrates how the microbial diversity of the oceans can be analyzed without necessarily

55

DOE Joint Genome Institute: Soybean Genome Analysis Reveals Pathways for  

NLE Websites -- All DOE Office Websites (Extended Search)

January 13, 2010 January 13, 2010 Soybean Genome Analysis Reveals Pathways for Improving Biodiesel, Disease Resistance, and Reducing Waste Runoff WALNUT CREEK, CA-Soybean, one of the most important global sources of protein and oil, is now the first legume species with a published complete draft genome sequence. The sequence and its analysis appear in the January 14 edition of the journal Nature. The research team comprised 18 institutions, including the U.S. Department of Energy Joint Genome Institute (DOE JGI), the U.S. Department of Agriculture-Agricultural Research Service (USDA-ARS), Purdue University and the University of North Carolina at Charlotte. The DOE, National Science Foundation, USDA and United Soybean Board supported the research. helix made of soybeans

56

Science  

NLE Websites -- All DOE Office Websites (Extended Search)

149802 149802 , 1291 (2007); 318 Science et al. L. Ozyuzer, Superconductors Emission of Coherent THz Radiation from www.sciencemag.org (this information is current as of November 29, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/318/5854/1291 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/318/5854/1291/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.sciencemag.org/cgi/content/full/318/5854/1291#related-content http://www.sciencemag.org/cgi/content/full/318/5854/1291#otherarticles

57

SCience  

NLE Websites -- All DOE Office Websites (Extended Search)

all all SCience Chicago Office Environment, Safety and Health Functions, Responsibilities, and Authorities Manual December 2012 ~5 {?JI-- l L-H1- I Roxanne E. Purucker, Manager Date SC-CH FRAM Revision 7 Office of Science - Chicago Office SC-CH Revision History TITLE: SC-CH Functions, Responsibilities, and Authorities Manual POINT OF CONTACT: Karl Moro SCMS MANAGEMENT SYSTEM: Environment, Safety and Health (ES&H) TO BE UPDATED: December 31, 2013 Revision Date Reason/Driver Description 5 Oct 10 Annual review and revision of the SC-CH ES&H Functions, Responsibilities, and Authorities Manual Changes were primarily made to address administrative and organizational changes and general improvement of text and presentation. I 6 Nov 11 Annual review and revision of

58

Fact Sheets : BioEnergy Science Center  

NLE Websites -- All DOE Office Websites (Extended Search)

Fact Sheets DOE Mission Focus: BioFuels US Department of Energy's Genomic Science Program DOE BioEnergy Science Center - fact sheet - 2011 DOE BioEnergy Science Center - fact sheet...

59

Genomics and Systems Biology  

NLE Websites -- All DOE Office Websites (Extended Search)

Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

60

mathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publisher  

E-Print Network (OSTI)

sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences

Calegari, Frank

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

DOE Joint Genome Institute: Preparing for a Thaw: How Arctic...  

NLE Websites -- All DOE Office Websites (Extended Search)

Research) To answer this question, researchers from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), the Earth Sciences Division (ESD) within Berkeley Lab, and the...

62

JGI Fungal Genomics Program  

SciTech Connect

Genomes of energy and environment fungi are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 50 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such 'parts' suggested by comparative genomics and functional analysis in these areas are presented here

Grigoriev, Igor V.

2011-03-14T23:59:59.000Z

63

CGAL: computing genome assembly likelihoods  

E-Print Network (OSTI)

SM, Lei M, Li J, et al: Genome sequencing in microfabricatedDe novo bacterial genome sequencing: millions of very shortGenome assembly, evaluation, likelihood, sequencing.

Rahman, Atif; Pachter, Lior

2013-01-01T23:59:59.000Z

64

Genomics Presentations from the 8th Meeting of the Genomic Standards Consortium (2009), held at the DOE JGI (Videos)  

DOE Data Explorer (OSTI)

\tA New ARM of the GSC: the RCN4GSC, Dawn Field and Peter Sterk \tStandards in Genomic Sciences (SIGS): An Open Access Journal of the Genomic Standards Consortium, George Garrity \tGSC8 Opening Remarks, Dawn Fields

65

PNNL: Biological Sciences Programs & Projects: FCSD  

NLE Websites -- All DOE Office Websites (Extended Search)

Projects Biological & Environmental Research-PNNL Proteomics Center for Systems Biology of EnteroPathogens DOE Genomic Science Program Foundational Scientific Focus Area (FSFA)...

66

Genomics and the human genome project: implications for psychiatry  

E-Print Network (OSTI)

and psychosis: a convergent functional genomics approach.Physiology & Genomics, 4, 8391. O LIPHANT , A. , B ARKER ,2004), 16(4), 294300 Genomics and the Human Genome Project:

Kelsoe, J R

2004-01-01T23:59:59.000Z

67

Palm Oil: Production, Processing, Uses, and CharacterizationChapter 3 Oil Palm Genomics  

Science Conference Proceedings (OSTI)

Palm Oil: Production, Processing, Uses, and Characterization Chapter 3 Oil Palm Genomics Food Science Health Nutrition Biochemistry Processing eChapters Food Science & Technology Health - Nutrition - Biochemistry Processing 0641F6393F

68

mathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publisher  

E-Print Network (OSTI)

& Number Theory mathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences publishersmathematical sciences

Skorobogatov, Alexei N.

69

Comparative genomic workflow  

E-Print Network (OSTI)

his article describes a workflow for identifying conserved patterns in noncoding regions of vertebrate genomes, with an intention of investigating possible functions of the conserved regions. The annotations of genomes are ...

Rajapakse, Jagath

70

Genome in a Bottle Consortium  

Science Conference Proceedings (OSTI)

Genome in a Bottle Consortium. Summary: NIST has organized the "Genome in a Bottle Consortium" to develop the reference ...

2013-03-15T23:59:59.000Z

71

Science and Public Policy  

SciTech Connect

The United States faces many issues that involve science. Issues ranging from climate change to nano-technology, from human genomics to modified food crops. What is the role that science plays in determining what the public policy for these issues should be? How as scientists should we respond to requests for advice?

Handler, Thomas [University of Tennessee

2012-11-28T23:59:59.000Z

72

BMC Genomics BioMed Central  

E-Print Network (OSTI)

Software Genome Annotation Transfer Utility (GATU): rapid annotation of viral genomes using a closely related reference genome

Vasily Tcherepanov; Angelika Ehlers; Chris Upton

2006-01-01T23:59:59.000Z

73

An integrative approach for genomic island prediction in Prokaryotic genomes  

Science Conference Proceedings (OSTI)

A genomic island (GI) is a segment of genomic sequence that is horizontally transferred from other genomes. The detection of genomic islands is extremely important to the medical research. Most of current computational approaches that use sequence composition ... Keywords: gene information, genomic islands, intergenic distance, sequence composition

Han Wang; John Fazekas; Matthew Booth; Qi Liu; Dongsheng Che

2011-05-01T23:59:59.000Z

74

Genome Sequence Databases (Overview): Sequencing and Assembly  

E-Print Network (OSTI)

complete microbial genome sequencing (you get what you payet al. (2005). Genome sequencing in open microfabricatedof problem solving in genome sequencing. Genome Research 8,

Lapidus, Alla L.

2009-01-01T23:59:59.000Z

75

JGI - Undergraduate Research in Functional Genomics  

NLE Websites -- All DOE Office Websites (Extended Search)

Education Microbial Genome Analysis Microbial Functional Genomics Undergraduate Research in Microbial Functional Genomics Genomics not only can answer questions about known genes,...

76

Genome Analysis and Systems Modeling Group  

NLE Websites -- All DOE Office Websites (Extended Search)

(Microbial Genomes) Pipeline, Comprehensive Genome Analysis Pipeline Genome Channel, Java applet for the comprehensive sequence-based view of genomes. Grail, a tool for the...

77

Bioconversion Science & Technology  

NLE Websites -- All DOE Office Websites (Extended Search)

BSD BSD EESD ORNL Bioconversion Science and Technology BioSciences Division Home Resources Publications People BST Students Former Members Links Contact Us Research Areas Production of Fuels and Chemicals Genomes to Life Biofuel Cells Bioprocessing of Fossil Fuels Biotreatment and Bioremediation Jonathan Mielenz, leader of the Bioconversion Science and Technology Group in ORNL's Biosciences Division, is studying a microbe that could prove more cost effective than current methods in transforming cellulose from sources such as switchgrass and poplar trees into ethanol. Bioconversion Science & Technology The Bioconversion Science and Technology group performs multidisciplinary R&D for the Department of Energy's (DOE) relevant applications of bioprocessing, especially with biomass. Bioprocessing combines the

78

JGI - Genomic Technologies  

NLE Websites -- All DOE Office Websites (Extended Search)

opportunities for technological access to our user services (including single cell genomics and DNA synthesis). Our Department serves at the interface between the Project...

79

JGI CSP Delivers First Moss Genome  

NLE Websites -- All DOE Office Websites (Extended Search)

13, 2007 13, 2007 DOE JGI Community Sequencing Program Delivers First Moss Genome WALNUT CREEK, CA--Messages from nearly a half-billion years ago, conveyed via the inventory of genes sequenced from a present-day moss, provide clues about the earliest colonization of dry land by plants. The U.S. Department of Energy Joint Genome Institute (DOE JGI) was among the leaders of an international effort uniting more than 40 institutions to complete the first genome sequencing project of a nonvascular land plant, the moss Physcomitrella patens. The team's insights into the code that enabled this seminal emergence and dominance of land by plants are published December 13 online in Science Express. Scanning electron micrograph of Physcomitrella patens gametophores (moss shoots).

80

Enhancer Identification through Comparative Genomics  

E-Print Network (OSTI)

through Comparative Genomics Axel Visel, James Bristow andWalnut Creek, CA 94598 USA. Genomics Division, MS 84-171,Len A. Pennacchio, Genomics Division, One Cyclotron Road, MS

Visel, Axel; Bristow, James; Pennacchio, Len A.

2006-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Genomic analysis of mouse tumorigenesis  

E-Print Network (OSTI)

The availability of the human and mouse genome sequences has spurred a growing interest in analyzing mouse models of human cancer using genomic techniques. Comparative genomic studies on mouse and human tumors can be ...

Tam, Mandy Chi-Mun

2006-01-01T23:59:59.000Z

82

Spectrogram analysis of genomes  

Science Conference Proceedings (OSTI)

We perform frequency-domain analysis in the genomes of various organisms using tricolor spectrograms, identifying several types of distinct visual patterns characterizing specific DNA regions. We relate patterns and their frequency characteristics to ... Keywords: DNA spectrograms, frequency-domain analysis, genome analysis

David Sussillo; Anshul Kundaje; Dimitris Anastassiou

2004-01-01T23:59:59.000Z

83

Legume Crop Genomics  

Science Conference Proceedings (OSTI)

This book will present this technical theme in a manner that should help many readers answer the question, "What is genomics?" And finally, this book should help readers formulate an opinion on the question, "Why is genomic research needed?" Legume Crop Ge

84

Genome Properties Database  

DOE Data Explorer (OSTI)

The Genome Properties system consists of a suite of "Properties" which are carefully defined attributes of prokaryotic organisms whose status can be described by numerical values or controlled vocabulary terms for individual completely sequenced genomes. Evaluation of these properties may take place via manual curation or by computer algorithms (numerical calculations or rules-based assignment of controlled vocabulary terms). The Genome Properties system has been designed to capture the widest possible range of attributes and currently encompasses taxonomic terms, genometric calculations, metabolic pathways, systems of interacting macromolecular components and quantitative and descriptive experimental observations (phenotypes) from the literature. Wherever possible, Genome Properties are linked to traceable lines of evidence and links are provided to data for any genes which are part of this evidence. The primary source of evidence linking genes to properties is homology modelling using Hidden Markov Models (HMMs) from the TIGRFAMs and Pfam databases. (Taken from the Genome Properties Home Page)(Specialized Interface)

Haft, Daniel H.; Selengut, Jeremy D.; Brinkac, Lauren M.; Zafar, Nikhat; White, Owen

85

Science Saturdays attract hundreds of students for lectures,...  

NLE Websites -- All DOE Office Websites (Extended Search)

lectures and hands-on activities centered on the science of rainbows, robotics and remote handling, the materials genome, crystals, biofuels, supercomputing, climate change...

86

Frontiers in Biological Sciences Seminar Series Presents Developing...  

NLE Websites -- All DOE Office Websites (Extended Search)

Frontiers in Biological Sciences Seminar Series Presents Developing Genome-Enabled Sustainable Lignocellulosic Biofuel Technologies at the Great Lakes Bioenergy Research Center...

87

*** CANCELED *** SCIENCE ON SATURDAY- "Finding a Needle in A...  

NLE Websites -- All DOE Office Websites (Extended Search)

*** SCIENCE ON SATURDAY- "Finding a Needle in A (Genomic) Haystack or How Can Computers Help Cure Cancer" Professor Olga G. Troyanskaya Lewis-Sigler Institute for...

88

JGI - FY2003 Sequencing for the DOE Microbial Genome Program  

NLE Websites -- All DOE Office Websites (Extended Search)

3 Sequencing for the 3 Sequencing for the DOE Microbial Genome Program For status information, see the Genome Projects section. For more information about the DOE Office of Science's Microbial Genome Program, see http://microbialgenomics.energy.gov/. For more information about microbial sequencing at JGI, contact David Bruce. Eukaryotes Organism Genome Size Emiliania huxleyi 220 Mb Ostreococcus lucimarinus 9.3 Mb Monosiga brevicollis Bacteria Organism Genome Size Anabaena variabilis ATCC 29413 7 Mb Burkholderia sp. 383 8.80 Mb Burkholderia vietnamiensis G4 8.40 Mb Chlorobium aggregatum Chlorobium chlorochromatii CaD3 2.6 Mb Chlorochromatium aggregatum Lake Dagow Crocosphaera watsonii WH 8501 6.40 Mb Kineococcus radiotolerans SRS30216 4.90 Mb Methylibium petroleiphilum PM1 4.60 Mb

89

JGI - FY2005 Sequencing for the DOE Microbial Genome Program  

NLE Websites -- All DOE Office Websites (Extended Search)

5 Sequencing for the 5 Sequencing for the DOE Microbial Genome Program For status information, see the Genome Projects section. For more information about the DOE Office of Science's Microbial Genome Program, see http://microbialgenomics.energy.gov/. For more information about microbial sequencing at JGI, contact David Bruce. Strains of Shewanella Organism Est. Genome Size Shewanella baltica OS195 5 Mb Shewanella sp. ANA-3 5 Mb Shewanella sp. MR-4 5 Mb Shewanella sp. MR-7 5 Mb Shewanella sp. W3-18-1 5 Mb Shewanella baltica OS223 5 Mb Strains of Chloroflexi Organism Est. Genome Size Chloroflexus aggregans DSM 9485 5 Mb Chloroflexus sp. Y-396-1 5 Mb Chlorothrix halophila (Candidatus) 5 Mb Herpetosiphon aurantiacus DSM 785 5 Mb Roseiflexus castenholzii HLO8 5 Mb Roseiflexus sp. strain RS-1 5 Mb

90

DOE Joint Genome Institute: DNA of Uncultured Organisms Sequenced Using  

NLE Websites -- All DOE Office Websites (Extended Search)

21, 2009 21, 2009 DNA of Uncultured Organisms Sequenced Using Novel Single-Cell Approach Download a Podcast of this Release! WALNUT CREEK, CA-Scientists from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) and the Bigelow Laboratory for Ocean Sciences have assembled high quality, contamination-free draft genomes of uncultured biodegrading microorganisms using a novel single cell genome sequencing approach. This proof of principle study, published in the April 23 edition of the journal PLoS One, offers researchers a new method to access and decipher the information embedded in genomes of interest with only minute quantities of DNA. "Most of the microbial genomes sequenced to date are derived from organisms cultured in the laboratory," said DOE JGI Director Eddy Rubin.

91

JGI - FY2002 Sequencing for the DOE Microbial Genome Program  

NLE Websites -- All DOE Office Websites (Extended Search)

2 Sequencing for the 2 Sequencing for the DOE Microbial Genome Program For status information, see the Genome Projects section. For more information about the DOE Office of Science's Microbial Genome Program, see http://microbialgenomics.energy.gov/. For more information about microbial sequencing at JGI, contact David Bruce. Eukaryotes Organism Genome Size Thalassiosira pseudonana CCMP 1335 (diatom) 32 Mb Lactic Acid Bacteria Organism Genome Size Bifidobacterium longum DJO10A 2.4 Mb Brevibacterium linens BL2 4.5 Mb Lactobacillus brevis ATCC 367 1.8 Mb Lactobacillus casei ATCC 334 2.8 Mb Lactobacillus delbrueckii ATCC BAA-365 1.6 Mb Lactobacillus gasseri ATCC 33323 1.9 Mb Lactococcus lactis subsp. cremoris SK11 2.6 Mb Leuconostoc mesenteroides ATCC 8293 2 Mb Oenococcus oeni PSU-1 1.8 Mb

92

Low Dose Radiation Research Program: Interaction of Genome and Cellular  

NLE Websites -- All DOE Office Websites (Extended Search)

of Genome and Cellular Micronenvioronment of Genome and Cellular Micronenvioronment Mina Bissell Life Sciences Division Lawrence Berkeley National Laboratory Why this Project While normal stoma can delay or prevent tumorigenesis, abnormal stromal components can promote tumor growth. Acquired or inherited mutations that alter stromal cell function can release the context-suppressed malignant cells. Literature spanning more than a century has shown that inflammation associated with tissue wounding can produce tunors. Radiation produces changes in reactive oxygen that are similar to inflammation and may represent a mechanism for radiation-induced damage. Project Goals To determine the underlying role of stromal alterations in controling genomic instability accompanying epithelial-mesenchyumal transformation.

93

Eukaryotic Genomics Data from the DOE Joint Genome Institute (JGI)  

DOE Data Explorer (OSTI)

From the JGI webportal users can choose Eukaryotic genomes from a photo list, access the JGI FTP directories to download data files, use the Tree of Life navigation tool, or choose a genome and go directly to a website specific to that one genome. The individual sites include direct access to download sequence files, BLAST, search, view and navigate the genomic annotations.

94

Granularity of genomics data in genome visualisation  

E-Print Network (OSTI)

Jakubowska,J. Hunt,E. Chalmers,M.J. DCS Technical Report Series pp 10 Dept of Computing Science, University of Glasgow

Jakubowska, J.; Hunt, E.

95

Comparative genomics of the core and accessory genomes of 48 Sinorhizobium strains comprising five genospecies  

E-Print Network (OSTI)

annotation and comparative genomics. Database (Oxford) 2009,et al. : Comparative genomics of the core and accessoryComparative genomics of the core and accessory genomes of 48

2013-01-01T23:59:59.000Z

96

Structural Genomics | Biosciences Division  

NLE Websites -- All DOE Office Websites (Extended Search)

Chart Site Index Inside BIO BIO Safety About Argonne Midwest Center for Structural Genomics Andrzej Joachimiak Director Bldg: 202. Room: Q 118 E-mail: andrzejj@anl.gov Phone:...

97

Human Genome Education Program  

Science Conference Proceedings (OSTI)

The funds from the DOE Human Genome Program, for the project period 2/1/96 through 1/31/98, have provided major support for the curriculum development and field testing efforts for two high school level instructional units: Unit 1, ''Exploring Genetic Conditions: Genes, Culture and Choices''; and Unit 2, ''DNA Snapshots: Peaking at Your DNA''. In the original proposal, they requested DOE support for the partial salary and benefits of a Field Test Coordinator position to: (1) complete the field testing and revision of two high school curriculum units, and (2) initiate the education of teachers using these units. During the project period of this two-year DOE grant, a part-time Field-Test Coordinator was hired (Ms. Geraldine Horsma) and significant progress has been made in both of the original proposal objectives. Field testing for Unit 1 has occurred in over 12 schools (local and non-local sites with diverse student populations). Field testing for Unit 2 has occurred in over 15 schools (local and non-local sites) and will continue in 12-15 schools during the 96-97 school year. For both curricula, field-test sites and site teachers were selected for their interest in genetics education and in hands-on science education. Many of the site teachers had no previous experience with HGEP or the unit under development. Both of these first-year biology curriculum units, which contain genetics, biotechnology, societal, ethical and cultural issues related to HGP, are being implemented in many local and non-local schools (SF Bay Area, Southern California, Nebraska, Hawaii, and Texas) and in programs for teachers. These units will reach over 10,000 students in the SF Bay Area and continues to receive support from local corporate and private philanthropic organizations. Although HGEP unit development is nearing completion for both units, data is still being gathered and analyzed on unit effectiveness and student learning. The final field testing result from this analysis will contribute to the final revisions of each unit during the second-year of this grant.

Richard Myers; Lane Conn

2000-05-01T23:59:59.000Z

98

Life sciences and environmental sciences  

Science Conference Proceedings (OSTI)

The DOE laboratories play a unique role in bringing multidisciplinary talents -- in biology, physics, chemistry, computer sciences, and engineering -- to bear on major problems in the life and environmental sciences. Specifically, the laboratories utilize these talents to fulfill OHER`s mission of exploring and mitigating the health and environmental effects of energy use, and of developing health and medical applications of nuclear energy-related phenomena. At Lawrence Berkeley Laboratory (LBL) support of this mission is evident across the spectrum of OHER-sponsored research, especially in the broad areas of genomics, structural biology, basic cell and molecular biology, carcinogenesis, energy and environment, applications to biotechnology, and molecular, nuclear and radiation medicine. These research areas are briefly described.

Not Available

1992-02-01T23:59:59.000Z

99

Life sciences and environmental sciences  

Science Conference Proceedings (OSTI)

The DOE laboratories play a unique role in bringing multidisciplinary talents -- in biology, physics, chemistry, computer sciences, and engineering -- to bear on major problems in the life and environmental sciences. Specifically, the laboratories utilize these talents to fulfill OHER's mission of exploring and mitigating the health and environmental effects of energy use, and of developing health and medical applications of nuclear energy-related phenomena. At Lawrence Berkeley Laboratory (LBL) support of this mission is evident across the spectrum of OHER-sponsored research, especially in the broad areas of genomics, structural biology, basic cell and molecular biology, carcinogenesis, energy and environment, applications to biotechnology, and molecular, nuclear and radiation medicine. These research areas are briefly described.

Not Available

1992-02-01T23:59:59.000Z

100

Evolutionary Genomics of Life in (and from) the Sea  

E-Print Network (OSTI)

web Genomes Online NIH Genome Sequencing Input NIH GenomesAbstract High throughput genome sequencing centers that werefunding sources of genome sequencing in the United States,

Boore, Jeffrey L.

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Genomics, Gene Expression and Other Studies in Soybean Rust  

E-Print Network (OSTI)

Joint Genome Institute Genomics, Gene Expression and otherRust Martha Luca Posada-Buitrago Ph.D Genomics DivisionEvolutionary Genomics DOE- Joint Genome Institute Lawrence

Posada-Buitrago, Martha Lucia

2005-01-01T23:59:59.000Z

102

Fueling the Future with Fungal Genomics  

E-Print Network (OSTI)

et al. 2008. Fungal genome sequencing and bioenergy. FungalCullen D, et al. 2008. Genome sequencing and analysis of theand lessons learned from genome sequencing. Methods Enzymol.

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

103

DOE Joint Genome Institute 2008 Progress Report  

E-Print Network (OSTI)

Martinez, D. , et al. Genome sequencing and analysis of thegroup, the HudsonAlpha Genome Sequencing Center, will expandnext-genera- tion genome sequencing and add capabilities to

Gilbert, David

2009-01-01T23:59:59.000Z

104

Requirements and standards for organelle genome databases  

E-Print Network (OSTI)

to the complete genome sequencing of many other organisms (guide the transition from human genome sequencing to being a04334; and Phakopsora genome sequencing direct funding).

Boore, Jeffrey L.

2006-01-01T23:59:59.000Z

105

DOE JGI Microbial Genomics & Metagenomics Workshops  

NLE Websites -- All DOE Office Websites (Extended Search)

DOE Joint Genome Institute Microbial Genomics & Metagenomics Workshops Walnut Creek, California The U.S. Department of Energy Joint Genome Institute (DOE JGI) will be offering...

106

VISTA - computational tools for comparative genomics  

E-Print Network (OSTI)

tools for comparative genomics Kelly A. Frazer 1 , LiorBerkeley, CA, 94720 Genomics Division, Lawrence Berkeleymultiple comparative genomics tools and provides users with

Frazer, Kelly A.; Pachter, Lior; Poliakov, Alexander; Rubin, Edward M.; Dubchak, Inna

2004-01-01T23:59:59.000Z

107

Fueling the Future with Fungal Genomics  

E-Print Network (OSTI)

JW. 2010. China's fungal genomics initiative: a whitepaper.and Saccharomycotina. BMC Genomics. 8, 325. Bailly J,Harnessing ectomycorrhizal genomics for ecological insights.

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

108

JGI - FY2004 Sequencing for the DOE Microbial Genome Program  

NLE Websites -- All DOE Office Websites (Extended Search)

4 Sequencing for the 4 Sequencing for the DOE Microbial Genome Program For status information, see the Genome Projects section. For more information about the DOE Office of Science's Microbial Genome Program, see http://microbialgenomics.energy.gov/. For more information about microbial sequencing at JGI, contact David Bruce. Chlorobia (avg:~2.4Mb) Organism Genome Size Chlorobium ferrooxidans DSM 13031 2.40 Mb Chlorobium limicola DSMZ 245 2.4 Mb Chlorobium phaeobacteroides BS1 2.4 Mb Chlorobium phaeobacteroides DSM 266 2.3 Mb Pelodictyon luteolum DSMZ 273 2.3 Mb Pelodictyon phaeoclathratiforme BU-1 (DSM 5477) 2.4 Mb Prosthecochloris aestuarii DSM 271 2.4 Mb Prosthecochloris vibrioformis DSM 265 2.4 Mb Chlorobaculum parvum n/a Chloroherpeton thalassium n/a Model Syntrophic Consortium

109

JGI - FY2001 Sequencing for the DOE Microbial Genome Program  

NLE Websites -- All DOE Office Websites (Extended Search)

1 Sequencing for the 1 Sequencing for the DOE Microbial Genome Program For status information, see the Genome Projects section. For more information about the DOE Office of Science's Microbial Genome Program, see http://microbialgenomics.energy.gov/. For more information about microbial sequencing at JGI, contact David Bruce. Organism Genome Size Burkholderia xenovorans LB400 8 Mb Chloroflexus aurantiacus J-10-fl 3 Mb Cupriavidus metallidurans CH34 6.8 Mb Cytophaga hutchinsonii ATCC 33406 4.4 Mb Desulfitobacterium halfniense DCB-2 4.7 Mb Enterococcus faecium DO 2.8 Mb Ferroplasma acidarmanus fer1 1.8 Mb Magnetococcus sp. MC-1 4.7 Mb Methanosarcina barkerii fusaro 4.8 Mb Nitrosomonas europaea ATCC 19718 2.8 Mb Nostoc punctiforme PCC 73102 9.2 Mb Novosphingobium aromaticivorans DSM 12444 4.2 Mb

110

JGI - FY2007 Sequencing for the DOE Microbial Genome Program  

NLE Websites -- All DOE Office Websites (Extended Search)

7 Sequencing for the 7 Sequencing for the DOE Microbial Genome Program For status information, see the Genome Projects section. For more information about the DOE Office of Science's Microbial Genome Program, see http://microbialgenomics.energy.gov/. For more information about microbial sequencing at JGI, contact David Bruce. Organism(s) Est. Genome Size Acremonium alcalophilum ATCC90507 40 MB Azolla Cyanobacterium, Arthrospira maxima, and Cyanobacterium JSC-1 NA bacterioplankton pool cDNA day, night, night + DOC1, night + DOC2 NA Clostridum carboxidivorans, Clostridium sp. strains, Clostridium straminisolvens, Clostridum thermocellum LQR1 DSM2360 , Clostridium thermocellum JW20 DSM 4150 Thermoanaerobacter italicus Ab9 DSM9252, T. ethanolicus X513, T. ethanoloicus X561, T. mathrani, Thermoanaerobacterium thermosaccharaolyticum, Thermoanaerobacterium xylanolyticum LX11 DSM7097 3.5-4.0 MB

111

Seventh Annual DOE Joint Genome Institute User Meeting Sponsored By  

NLE Websites -- All DOE Office Websites (Extended Search)

Seventh Annual Seventh Annual DOE Joint Genome Institute User Meeting Sponsored By U.S. Department of Energy Office of Science March 20-22, 2012 Walnut Creek Marriott Walnut Creek, California Contents Speaker Presentations .......................................................................................................... 1 Poster Presentations ........................................................................................................... 13 Attendees ............................................................................................................................ 83 Author Index ....................................................................................................................... 89 Abstracts alphabetical by speaker

112

Microbial Genomics Data from the DOE Joint Genome Institute (JGI)  

DOE Data Explorer (OSTI)

As of March 2008, The Joint Genome Institute has released 296 Prokaryotic microbial sites, with 216 in finished status.

113

Genomic Advances to Improve Biomass for Biofuels (Genomics and Bioenergy)  

DOE Green Energy (OSTI)

Lawrence Berkeley National Lab bioscientist Daniel Rokhsar discusses genomic advances to improve biomass for biofuels. He presented his talk Feb. 11, 2008 in Berkeley, California as part of Berkeley Lab's community lecture series. Rokhsar works with the U.S. Department of Energy's Joint Genome Institute and Berkeley Lab's Genomics Division.

Rokhsar, Daniel

2008-02-11T23:59:59.000Z

114

Biological Sciences at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Sciences Biological Sciences Biological Sciences Better knowledge of biomolecules and processes they undergo is vital for achieving a predictive, systems-level understanding of complex biological systems that have potential use in bioenergy, carbon cycling and biosequestration, and biogeochemistry. Areas that NERSC helps to enable include: Research activities using genomics and systems biology to understand plants and microbes. Developing and applying atomistic-molecular to coarse-grained mathematical models of potential energy surfaces, characterizing these surfaces through sampling techniques and finally generating ensemble or time averaged physical properties of biological phenomena. Fundamental research in the redesign of microbial metabolic processes to harness their potential in the conversion of biomass to

115

Science Afternoons  

Science Conference Proceedings (OSTI)

Science Afternoon: From Invention to Marketplace. Science Afternoon: Focus on ... Understand It? Science Afternoons. To continue ...

2013-01-16T23:59:59.000Z

116

Mammalian comparative genomics and epigenomics  

E-Print Network (OSTI)

The human genome sequence can be thought of as an instruction manual for our species, written and rewritten over more than a billion of years of evolution. Taking a complete inventory of our genome, dissecting its genes ...

Mikkelsen, Tarjei Sigurd, 1978-

2009-01-01T23:59:59.000Z

117

Genome in a Bottle Consortium Workshop  

Science Conference Proceedings (OSTI)

Genome in a Bottle Consortium Workshop. Purpose: NIST ... well. Related Project(s): Genome in a Bottle Consortium. Details: ...

2013-08-13T23:59:59.000Z

118

DOE Joint Genome Institute: Establishing Standard Definitions for Genome  

NLE Websites -- All DOE Office Websites (Extended Search)

October 8, 2009 October 8, 2009 Establishing Standard Definitions for Genome Sequences Download a podcast of this release! WALNUT CREEK, CA-In 1996, researchers from major genome sequencing centers around the world convened on the island of Bermuda and defined a finished genome as a gapless sequence with a nucleotide error rate of one or less in 10,000 bases. This effectively set the quality target for the human genome effort and was quickly applied to other genome projects. If a genome sequence didn't meet this stringent criterion, it was simply considered a "draft." More than a decade later, researchers are finding that with the advent of the latest sequencing technologies the terms "draft" and "finished" are no longer sufficient to describe the varying levels of genome sequence

119

Materials Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Materials Science science-innovationassetsimagesicon-science.jpg Materials Science National security depends on science and technology. The United States relies on Los Alamos...

120

Genomics and Systems Biology  

NLE Websites -- All DOE Office Websites (Extended Search)

such as energy, agriculture, and environmental cleanup. Get Expertise Babetta Marrone Biofuels Program Manager Email Cheryl Kuske DOE BER Biological System Science Division...

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121

Cellulases: ambiguous nonhomologous enzymes in a genomic perspective  

NLE Websites -- All DOE Office Websites (Extended Search)

Cellulases: Cellulases: ambiguous nonhomologous enzymes in a genomic perspective Leonid O. Sukharnikov 1,2,4 , Brian J. Cantwell 1,4 , Mircea Podar 1,2,4 and Igor B. Zhulin 1,3,4,5 1 BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA 2 Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA 3 Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA 4 Graduate School of Genome Science and Technology, University of Tennessee, Knoxville, TN 37996, USA 5 Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA The key material for bioethanol production is cellulose, which is one of the main components of the plant cell wall. Enzymatic depolymerization of cellulose is an essential step in bioethanol production, and can be accomplished by fungal and bacterial cellulases. Most

122

Claire M. Fraser, 2002 | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Page Life Sciences: For her contributions to genome analysis technology, its extension to the understanding of microbial diversity and its application to human pathogens...

123

JGI - Intro to Genomics 1  

NLE Websites -- All DOE Office Websites (Extended Search)

An Introduction to Genomics: The Human Genome and Beyond An Introduction to Genomics: The Human Genome and Beyond 1 | 2 | 3 | 4 | Next>> What is genomics? THE HUMAN BODY consists of trillions of cells. Almost all contain an entire genome--the complete set of inherited genetic information encoded in our DNA. When humans reproduce, the parents' sperm and egg DNA combine to contribute a genome's worth of genetic information to the fertilized embryo. That same information is in each of the cells that eventually make up an organism. cell, DNA helix, and protein structure Some segments of DNA, called genes or "coding" DNA, contain the chemical recipe that determines particular traits; genetics is the study of the inheritance and function of these genes. Scientists now estimate that humans have about 30,000 genes, located along threadlike, tightly coiled

124

Genomics Division Home  

NLE Websites -- All DOE Office Websites (Extended Search)

PIs PIs Mark Biggin Jim Bristow Jan-Fang Cheng Inna Dubchak Suzanna Lewis Chris Mungall Len Pennacchio Eddy Rubin Axel Visel Divisional Information Support Staff Seminars Diversity Directory Contact Us The characterization and analysis of genome sequences from such diverse organisms as humans to the most primitive soil microbe represent a watershed opportunity for biology. The Genomics Division is taking advantage of this wealth of new information. While it is well known that DNA encodes the basic blue print of life, it is not known how best to interpret most of this information. To address this question, laboratories within the division are developing computational, biochemical, genetic, and imaging methods to decipher the complex sequence motifs that control RNA transcription, DNA replication, and chromosome structure. The Division is

125

The US Department of Energy Joint Genome Institute Microbial Genome Program  

E-Print Network (OSTI)

Institute A typical genome sequencing project AssemblyInstitute A typical genome sequencing project AssemblyJGI Microbial Sequencing US DOE Joint Genome Institute JGI

Lapidus, Alla

2005-01-01T23:59:59.000Z

126

A physical map of the papaya genome with integrated genetic map and genome sequence  

E-Print Network (OSTI)

As a part of the genome sequencing project, we constructed ational papaya whole genome sequencing may be carried out inframework to guide the genome sequencing of related species.

2009-01-01T23:59:59.000Z

127

Comparative genomic analysis of fungal genomes reveals intron-rich ancestors  

E-Print Network (OSTI)

remain debated. Genome sequencing and comparative analysisInternational Human Genome Sequencing Consortium: Finishingreinhardtii genome structure using large-scale sequencing of

Stajich, Jason E; Dietrich, Fred S; Roy, Scott W

2007-01-01T23:59:59.000Z

128

Mitochondrial genome sequences and comparative genomics of Phytophthora ramorum and P. sojae  

E-Print Network (OSTI)

sequences and comparative genomics of Phytophthora ramorumAnnotation and comparative genomics - Annotation of codingtools for comparative genomics. Nuc Acids Res July 1:32:

Martin, Frank N.; Douda, Bensasson; Tyler, Brett M.; Boore, Jeffrey L.

2007-01-01T23:59:59.000Z

129

Coral Reef Genomics: Developing tools for functional genomics of coral symbiosis  

E-Print Network (OSTI)

Coral Reef Genomics: Developing toolsfor functional genomics of coral symbiosis Jodi SCHWARZ 1 ,symbiosis functional genomics cDNA microarray ABSTRACT

Schwarz, Jodi; Brokstein, Peter; Manohar, Chitra; Coffroth, Mary Alice; Szmant, Alina; Medina, Monica

2008-01-01T23:59:59.000Z

130

DOE Joint Genome Institute: Brown Tide Culprit Sequenced: Genome...  

NLE Websites -- All DOE Office Websites (Extended Search)

Culprit Sequenced: Genome of the First of Algal Bloom Species WALNUT CREEK, Calif.- Algae play key roles in the global carbon cycle, helping sequester significant amounts of...

131

BER Science Network Requirements  

Science Conference Proceedings (OSTI)

The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the US Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In April 2010 ESnet and the Office of Biological and Environmental Research, of the DOE Office of Science, organized a workshop to characterize the networking requirements of the science programs funded by BER. The requirements identified at the workshop are summarized and described in more detail in the case studies and the Findings section. A number of common themes emerged from the case studies and workshop discussions. One is that BER science, like many other disciplines, is becoming more and more distributed and collaborative in nature. Another common theme is that data set sizes are exploding. Climate Science in particular is on the verge of needing to manage exabytes of data, and Genomics is on the verge of a huge paradigm shift in the number of sites with sequencers and the amount of sequencer data being generated.

Dart, Eli; Tierney, Brian

2010-11-01T23:59:59.000Z

132

Salt Stress in Desulfovibrio vulgaris Hildenborough: An integrated genomics approach  

E-Print Network (OSTI)

2002. Integrating cancer genomics and proteomics in theWeb site for comparative genomics. Genome Res 15:1015-22.Hildenborough: An integrated genomics approach. Aindrila

Mukhopadhyay, Aindrila

2010-01-01T23:59:59.000Z

133

Population genomics: Whole-genome analysis of polymorphism and divergence in Drosophila simulans  

E-Print Network (OSTI)

PLoS BIOLOGY Population Genomics: Whole-Genome Analysis ofwww.plosbiology.org Population Genomics of D. simulans Table11 | e310 Population Genomics of D. simulans Table S15. GO

2007-01-01T23:59:59.000Z

134

Findiing Science with Science Page 1 Finding Science with Science  

E-Print Network (OSTI)

Findiing Science with Science Page 1 Finding Science with Science: Evaluating the Use Stojanovicd , Femke Reitsmae , Lukasz Korczynskif and Boyan Brodaricg a Centre for Geospatial Science of Earth and Ocean Sciences, Cardiff University, Cardiff, UK; e Department of Geography, University

Stock, Kristin

135

DOI: 10.1126/science.1241459 , 357 (2013);342Science  

E-Print Network (OSTI)

DOI: 10.1126/science.1241459 , 357 (2013);342Science et al.Marc J. Lajoie Genomically Recoded.html#related found at: can berelated to this articleA list of selected additional articles on the Science Web sites articles hosted by HighWire Press; see:cited byThis article has been registered trademark of AAAS. is aScience

Church, George M.

136

Single Cell Whole Genome Amplification  

NLE Websites -- All DOE Office Websites (Extended Search)

Single Cell Whole Genome Amplification Single Cell Whole Genome Amplification of Uncultivated Organisms Mircea Podar , Martin Keller , and Philip Hugenholtz (* ü ) Abstract Whole genome amplification of single cells is emerging as a powerful technique for accessing the genomes of individual members of microbial communi- ties without the complication of identifying the source of sequence data posed by shotgun sequencing of environmental samples (metagenomics). This method holds particular promise for the molecular unveiling of uncultivated organisms that com- prise the bulk of the microbial diversity and functionality on our planet. 1 Introduction Over the last two decades, it has become increasingly apparent that microbial diversity

137

genome109280 634..641  

NLE Websites -- All DOE Office Websites (Extended Search)

(http: www.phytozome.net), Selaginella moellendorffii (http:www. phytozome.net), Sorghum bicolor (http:genome.jgi-psf.org Sorbi1), Vitis vinifera (http:...

138

ORNL Genome Analysis Pipeline - Eukaryotic  

NLE Websites -- All DOE Office Websites (Extended Search)

Grail (Microbial Gene Prediction System Internet Link) GrailEXP Genome Analysis Pipeline DomainParser PROSPECT (PROtein Structure Prediction and Evaluation Computer...

139

Science Pillars  

NLE Websites -- All DOE Office Websites (Extended Search)

Environment Feature Stories Public Reading Room: Environmental Documents, Reports LANL Home Phonebook Calendar Video Science & Innovation Science Pillars Science Pillars...

140

Rooted in Wonder: Joint Genome Institute Study Reveals Amazing World  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Rooted in Wonder: Joint Genome Institute Study Reveals Amazing Rooted in Wonder: Joint Genome Institute Study Reveals Amazing World Underfoot Rooted in Wonder: Joint Genome Institute Study Reveals Amazing World Underfoot August 13, 2012 - 2:33pm Addthis By developing a better understanding of the microbes that affect the growth of other plants (crops like corn or wheat) researchers may be able to improve their growth -- or provide better care for them in times of drought. By developing a better understanding of the microbes that affect the growth of other plants (crops like corn or wheat) researchers may be able to improve their growth -- or provide better care for them in times of drought. Charles Rousseaux Charles Rousseaux Senior Writer, Office of Science What Is A Weed It's also known as a mouse-ear cress. The scientific name is Arababidopsis thaliana.

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While these samples are representative of the content of NLEBeta,
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We encourage you to perform a real-time search of NLEBeta
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141

DOE Joint Genome Institute 2008 Progress Report  

Science Conference Proceedings (OSTI)

While initially a virtual institute, the driving force behind the creation of the DOE Joint Genome Institute in Walnut Creek, California in the Fall of 1999 was the Department of Energy's commitment to sequencing the human genome. With the publication in 2004 of a trio of manuscripts describing the finished 'DOE Human Chromosomes', the Institute successfully completed its human genome mission. In the time between the creation of the Department of Energy Joint Genome Institute (DOE JGI) and completion of the Human Genome Project, sequencing and its role in biology spread to fields extending far beyond what could be imagined when the Human Genome Project first began. Accordingly, the targets of the DOE JGI's sequencing activities changed, moving from a single human genome to the genomes of large numbers of microbes, plants, and other organisms, and the community of users of DOE JGI data similarly expanded and diversified. Transitioning into operating as a user facility, the DOE JGI modeled itself after other DOE user facilities, such as synchrotron light sources and supercomputer facilities, empowering the science of large numbers of investigators working in areas of relevance to energy and the environment. The JGI's approach to being a user facility is based on the concept that by focusing state-of-the-art sequencing and analysis capabilities on the best peer-reviewed ideas drawn from a broad community of scientists, the DOE JGI will effectively encourage creative approaches to DOE mission areas and produce important science. This clearly has occurred, only partially reflected in the fact that the DOE JGI has played a major role in more than 45 papers published in just the past three years alone in Nature and Science. The involvement of a large and engaged community of users working on important problems has helped maximize the impact of JGI science. A seismic technological change is presently underway at the JGI. The Sanger capillary-based sequencing process that dominated how sequencing was done in the last decade is being replaced by a variety of new processes and sequencing instruments. The JGI, with an increasing number of next-generation sequencers, whose throughput is 100- to 1,000-fold greater than the Sanger capillary-based sequencers, is increasingly focused in new directions on projects of scale and complexity not previously attempted. These new directions for the JGI come, in part, from the 2008 National Research Council report on the goals of the National Plant Genome Initiative as well as the 2007 National Research Council report on the New Science of Metagenomics. Both reports outline a crucial need for systematic large-scale surveys of the plant and microbial components of the biosphere as well as an increasing need for large-scale analysis capabilities to meet the challenge of converting sequence data into knowledge. The JGI is extensively discussed in both reports as vital to progress in these fields of major national interest. JGI's future plan for plants and microbes includes a systematic approach for investigation of these organisms at a scale requiring the special capabilities of the JGI to generate, manage, and analyze the datasets. JGI will generate and provide not only community access to these plant and microbial datasets, but also the tools for analyzing them. These activities will produce essential knowledge that will be needed if we are to be able to respond to the world's energy and environmental challenges. As the JGI Plant and Microbial programs advance, the JGI as a user facility is also evolving. The Institute has been highly successful in bending its technical and analytical skills to help users solve large complex problems of major importance, and that effort will continue unabated. The JGI will increasingly move from a central focus on 'one-off' user projects coming from small user communities to much larger scale projects driven by systematic and problem-focused approaches to selection of sequencing targets. Entire communities of scientists working in a particular field, such as feeds

Gilbert, David

2009-03-12T23:59:59.000Z

142

Science DMZ  

NLE Websites -- All DOE Office Websites (Extended Search)

ESnet Overview ESnet Staff Governance Our Network Case Studies OSCARS Case Studies Science DMZ Case Studies Science DMZ CU Science DMZ Penn State & VTTI Science DMZ NOAA...

143

Genome Majority Vote (GMV), Version 0.x  

NLE Websites -- All DOE Office Websites (Extended Search)

Genome Majority Vote (GMV), Version 0.x Genome Majority Vote (GMV), Version 0.x The pipeline runs PRODIGAL gene predictions on all genomes, runs pan-reciprocal BLAST, and...

144

The evolution of genome size in ants  

E-Print Network (OSTI)

for future whole-genome sequencing projects. Page 1 of 9 (genotyping to whole-genome sequencing [1-3]. The genomeconsideration for whole-genome sequencing programs, our

Tsutsui, Neil D; Suarez, Andrew V; Spagna, Joseph C; Johnston, J Spencer

2008-01-01T23:59:59.000Z

145

One Bacterial Cell, One Complete Genome  

E-Print Network (OSTI)

Bader JS, et al. (2005) Genome sequencing in microfabricatedDR (2006) Whole-genome re-sequencing. Curr Opin Genet DevSingle cell MDA and genome sequencing The yellow portion of

Woyke, Tanja

2010-01-01T23:59:59.000Z

146

Rearrangement Phylogeny of Genomes in Contig Form  

Science Conference Proceedings (OSTI)

There has been a trend in increasing phylogenetic coverage for genome sequencing while decreasing the sequencing coverage for each genome. With lower coverage, there is an increasing number of genomes being published in contig form. Rearrangement algorithms, ...

Adriana Muoz; David Sankoff

2009-04-01T23:59:59.000Z

147

PLATCOM: a platform for computational comparative genomics  

E-Print Network (OSTI)

The exponential accumulation of genomic sequence data demands systematic analysis of genetic information and requires use of various computational approaches to handle such huge sets of genomic data. Comparative genomics,

Kwangmin Choi; Jeong-hyeon Choi; Amit Saple; Zhiping Wang; Jason Lee; Sun Kim

2005-01-01T23:59:59.000Z

148

Genome Halving by Block Interchange  

E-Print Network (OSTI)

We address the problem of finding the minimal number of block interchanges (exchange of two intervals) required to transform a duplicated linear genome into a tandem duplicated linear genome. We provide a formula for the distance as well as a polynomial time algorithm for the sorting problem.

Thomas, Antoine; Varr, Jean-Stphane

2011-01-01T23:59:59.000Z

149

BMC Genomics BioMed Central  

E-Print Network (OSTI)

Research article What can you do with 0.1 genome coverage? A case study based on a genome survey of the scuttle fly Megaselia scalaris (Phoridae)

David A Rasmussen; Mohamed Af Noor

2009-01-01T23:59:59.000Z

150

JGI - Distinguished Postdoctoral Fellow in Genomics  

NLE Websites -- All DOE Office Websites (Extended Search)

Distinguished Postdoctoral Fellow in Genomics The Department of Energy Joint Genome Institute (DOE JGI) in Walnut Creek, CA is soliciting Postdoctoral Fellows working in the...

151

Yeast Ancestral Genome Reconstructions - CECM - Simon Fraser ...  

E-Print Network (OSTI)

on eukaryotic nuclear genomes are based on parsimony (some statistical methods have been used on mitochondrial or bacterial genomes, see Darling et al.

152

Materials Science  

Science Conference Proceedings (OSTI)

Materials Science. Summary: ... Description: Group focus in materials science (inkjet metrology, micro-macro, advanced characterizations). ...

2012-10-02T23:59:59.000Z

153

Draft Genome Sequence  

NLE Websites -- All DOE Office Websites (Extended Search)

Draft Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and Gas Vesicles Peter C. Fineran, a Marina C. Iglesias Cans, a Joshua P. Ramsay, b Nabil M. Wilf, b Desiree Cossyleon, a Matthew B. McNeil, a Neil R. Williamson, b Rita E. Monson, b S. Anette Becher, c Jo-Ann L. Stanton, d Kim Brügger, e Steven D. Brown, f George P. C. Salmond b Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand a ; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom b ; AgResearch Ltd., Invermay Agricultural Centre, Mosgiel, New Zealand c ; Department of Anatomy, University of Otago, Dunedin, New Zealand d ; EASIH, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom e ; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge,

154

USDA-DOE Make Available $4 Million for Biomass Genomics Research | U.S. DOE  

NLE Websites -- All DOE Office Websites (Extended Search)

USDA-DOE Make USDA-DOE Make Available $4 Million for Biomass Genomics Research News Featured Articles Science Headlines 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Presentations & Testimony News Archives Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 10.12.06 USDA-DOE Make Available $4 Million for Biomass Genomics Research Print Text Size: A A A Subscribe FeedbackShare Page ST. LOUIS, MO - The U.S. Departments of Energy and Agriculture (DOE and USDA) today announced $4 million for bio-based fuels research that will accelerate the development of alternative fuels. The departments issued a solicitation for research proposals for new plant feedstock genomics research projects. Dr. Raymond L. Orbach, DOE Under Secretary for Science,

155

DOE Joint Genome Institute: Spikemoss Genome Offers New Paths...  

NLE Websites -- All DOE Office Websites (Extended Search)

5, 2011 Spikemoss Genome Offers New Paths for Biofuels Research--Bridges Plant Development Gap WALNUT CREEK, Calif.- It's not quite Christmas, but the DNA sequence of a small plant...

156

Human genome. 1993 Program report  

SciTech Connect

The purpose of this report is to update the Human Genome 1991-92 Program Report and provide new information on the DOE genome program to researchers, program managers, other government agencies, and the interested public. This FY 1993 supplement includes abstracts of 60 new or renewed projects and listings of 112 continuing and 28 completed projects. These two reports, taken together, present the most complete published view of the DOE Human Genome Program through FY 1993. Research is progressing rapidly toward 15-year goals of mapping and sequencing the DNA of each of the 24 different human chromosomes.

Not Available

1994-03-01T23:59:59.000Z

157

SCIENCE CHINA Technological Sciences  

E-Print Network (OSTI)

SCIENCE CHINA Technological Sciences © Science China Press and Springer-Verlag Berlin Heidelberg distribution and its relationship with soil water and salt under mulched drip irrigation in Xinjiang of China of Hydroscience and Engineering, Tsinghua University, Beijing 100084, China Received July 8, 2010; accepted

Ahmad, Sajjad

158

Annotation-based genome-wide SNP discovery in the large and complex Aegilops tauschii genome using next-generation sequencing without a reference genome sequence  

E-Print Network (OSTI)

and physical maps, genome sequencing, marker-assistedof scaffolds during genome sequencing. To use RJs in SNPallows for deep genome coverage sequencing, a prerequisite

2011-01-01T23:59:59.000Z

159

Information entropy based methods for genome comparison  

Science Conference Proceedings (OSTI)

A plethora of biologically useful information lies obscured in the genomes of organisms. Encoded within the genome of an organism is the information about its evolutionary history. Evolutionary signals are scattered throughout the genome. Bioinformatics ... Keywords: clustering, genome comparison, segmentation, sequence alignment, shannon entropy

Mehul Jani; Rajeev K. Azad

2013-05-01T23:59:59.000Z

160

DOE Joint Genome Institute 2008 Progress Report  

E-Print Network (OSTI)

biofuel production. Diatom Genome Helps Explain Their Success in Capturing Carbon Diatoms, mighty microscopic algae,

Gilbert, David

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Synthetic Genomics: Options for Governance  

E-Print Network (OSTI)

Gene and genome synthesis, that is, constructing long stretches of DNA from constituent chemicals, provides scientists with new and unparalleled capabilities both for understanding biology and for using it for beneficial ...

Garfinkel, Michele

2007-10-17T23:59:59.000Z

162

JGI - 2009 Genome Sequencing Targets  

NLE Websites -- All DOE Office Websites (Extended Search)

July 2, 2008 July 2, 2008 Pine Tree, Boat-Boring Bivalve "Bugs", Duck Weed, Oil-Producing Microalgae, Stinkbird Gut, 40 Others Top DOE Joint Genome Institute 2009 Genome Sequencing Targets WALNUT CREEK, CA-In the continuing effort to tap the vast, unexplored reaches of the earth's microbial and plant domains for bioenergy and environmental applications, the DOE Joint Genome Institute (DOE JGI) has announced its latest portfolio of DNA sequencing projects that it will undertake in the coming year. The 44 projects, culled from nearly 150 proposals received through the Community Sequencing Program (CSP), represent over 60 billion nucleotides of data to be generated through this biodiversity sampling campaign-roughly the equivalent of 20 human genomes. "The scientific and technological advances enabled by the information

163

Closing Keynote Presentation on the Genomics of Energy and the Environment (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

Science Conference Proceedings (OSTI)

Steve Benner, a distinguished chemist at the Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology, provides the closing keynote address for the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

Benner, Stephen [Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology

2012-03-22T23:59:59.000Z

164

PNNL: Biological Sciences: Fundamental and Computational Sciences  

NLE Websites -- All DOE Office Websites (Extended Search)

We perform Biological Systems Science research using prediction and We perform Biological Systems Science research using prediction and experimentation to understand the design of biological systems, translating the genome to functional capabilities for applications to energy, environment, and health. Microbial community research at PNNL is focusing on environment and energy processes, and rational design and development of new bioprocesses, while our health-related research is centering on how multicellular systems, tissues and organisms respond to disease and exposure to the environment. Dayle Smith PNNL and Collaborators Receive ARPA-E Award for Gas-to-Liquid Fuel Biocatalysis Congratulations to Pacific Northwest National Laboratory computational scientist Dr. Dayle Smith, who is part of a team that recently received a

165

Science Highlights  

NLE Websites -- All DOE Office Websites (Extended Search)

Science Highlights Science Highlights Print Science Highlights Featured scientific research based on publications resulting from work done at the ALS. Highlights are nominated by...

166

131Cognitive Science COGNITIVE SCIENCE  

E-Print Network (OSTI)

131Cognitive Science COGNITIVE SCIENCE PROFESSOR ELMES* MAJOR A major in cognitive science leading courses: Cognitive Science 110, 395, 403, 473; Computer Science 111, 211; Philosophy 106, 313; Psychology Science: Com- puter Science 295 (LISP, PROLOG or C), 313, 315; Psychology 207 b. Philosophical Foundations

Marsh, David

167

Implications of structural genomics target selection strategies: Pfam5000, whole genome, and random approaches  

E-Print Network (OSTI)

SK, Bonanno JB. Structural genomics. Methods Biochem AnalMizuguchi K. Structural genomics: an overview. Prog BiophysSE. A tour of structural genomics. Nat Rev Genet 2001;2(10):

Chandonia, John-Marc; Brenner, Steven E.

2004-01-01T23:59:59.000Z

168

Mapping our genes: The genome projects: How big, how fast  

DOE Green Energy (OSTI)

For the past 2 years, scientific and technical journals in biology and medicine have extensively covered a debate about whether and how to determine the function and order of human genes on human chromosomes and when to determine the sequence of molecular building blocks that comprise DNA in those chromosomes. In 1987, these issues rose to become part of the public agenda. The debate involves science, technology, and politics. Congress is responsible for /open quotes/writing the rules/close quotes/ of what various federal agencies do and for funding their work. This report surveys the points made so far in the debate, focusing on those that most directly influence the policy options facing the US Congress. Congressional interest focused on how to assess the rationales for conducting human genome projects, how to fund human genome projects (at what level and through which mechanisms), how to coordinate the scientific and technical programs of the several federal agencies and private interests already supporting various genome projects, and how to strike a balance regarding the impact of genome projects on international scientific cooperation and international economic competition in biotechnology. OTA prepared this report with the assistance of several hundred experts throughout the world. 342 refs., 26 figs., 11 tabs.

none,

1988-04-01T23:59:59.000Z

169

Genomics.energy.gov--genome programs of the U.S. Department of...  

NLE Websites -- All DOE Office Websites (Extended Search)

in environmental-waste cleanup, energy production, carbon cycling, and biotechnology. Genomics Image Gallery Visit this site for free downloadable, high-resolution, genomics...

170

DOE Joint Genome Institute: Unraveling the Threads: Simplest cotton genome  

NLE Websites -- All DOE Office Websites (Extended Search)

December 19, 2012 December 19, 2012 Unraveling the Threads: Simplest cotton genome offers clues for fiber improvements From the stockings decorating mantles to the new outfits in display windows calling to shoppers, cotton is woven into the fabric of the holiday season. For bioenergy researchers, however, fiber composition matters more than color and texture as each cotton strand is composed of more than two dozen coils of cellulose, a target biomass for next-generation biofuels. In the December 20, 2012 edition of Nature, an international consortium of researchers from 31 institutions including a team from the U.S. Department of Energy Joint Genome Institute (DOE JGI) present a high-quality draft assembly of the simplest cotton (Gossypium raimondii) genome. Additionally,

171

DOE Joint Genome Institute Completes Soybean Genome- Data Released to  

NLE Websites -- All DOE Office Websites (Extended Search)

Press Release: December 8, 2008 Press Release: December 8, 2008 DOE Joint Genome Institute Completes Soybean Genome- Data Released to Advance Biofuel, Food, & Feed Research WALNUT CREEK, CA- The U.S. Department of Energy Joint Genome Institute (DOE JGI) has released a complete draft assembly of the soybean (Glycine max) genetic code, making it widely available to the research community to advance new breeding strategies for one of the world's most valuable plant commodities. Soybean not only accounts for 70 percent of the world's edible protein, but also is an emerging feedstock for biodiesel production. Soybean is second only to corn as an agricultural commodity and is the leading U.S. agricultural export. DOE JGI's interest in sequencing the soybean centers on its use for biodiesel, a renewable, alternative fuel with the highest energy content of

172

Joint Genome Institute Progress Report 2002-2005  

E-Print Network (OSTI)

S, et al. Comparative genome sequencing of DrosophilaInternational Human Genome Sequencing Consortium. FinishingWhile NIH-funded genome sequencing activities largely

Gilbert, David

2005-01-01T23:59:59.000Z

173

Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity  

E-Print Network (OSTI)

management of the genome sequencing. References Altschul,species revealed the core genome, sequencing of 12 isolatesrevealed by ongoing genome sequencing projects. Although

Walker, C.B.

2010-01-01T23:59:59.000Z

174

Genomics, Gene Expression and Other Studies in Soybean Rust  

E-Print Network (OSTI)

by Christine Stone GENOME SEQUENCING PROJECT PhakopsoraUS DOE Joint Genome Institute DNA sequencing process LibraryUS DOE Joint Genome Institute DNA sequencing process Rolling

Posada-Buitrago, Martha Lucia

2005-01-01T23:59:59.000Z

175

Genome Project Standards in a New Era of Sequencing  

E-Print Network (OSTI)

for clone- based human genome sequencing, this finishing20850,USA HumanGenomeSequencingCenter,BaylorCollegeUSA HudsonAlphaGenomeSequencingCenter,HudsonAlpha

Hostetler, J.

2010-01-01T23:59:59.000Z

176

Complete genome sequence of Desulfomicrobium baculatum type strain (XT)  

E-Print Network (OSTI)

is deposited in Genome sequencing and annotation Genomeof Life, GEBA Table 2. Genome sequencing project informationand DNA isolation Genome sequencing and assembly tions to

Copeland, Alex

2010-01-01T23:59:59.000Z

177

Genomic Sequencing of Single Microbial Cells from Environmental Samples  

E-Print Network (OSTI)

as function of the genome sequencing effort. AdditionalYJ, Chen Z, et al. : Genome sequencing in microfabricatedof whole genome amplification and sequencing. Mechanical

Ishoey, Thomas

2010-01-01T23:59:59.000Z

178

Genomic analysis of high pressure adaptation in deep sea bacteria  

E-Print Network (OSTI)

This makes the genome sequencing project of Carnobacteriumpiezophile to undergo genome sequencing. Investigation intoMarine Microbial Genome Sequencing project. The initial

Stratton, Taylor Kristen

2008-01-01T23:59:59.000Z

179

Complete genome sequence of Acidimicrobium ferrooxidans type strain (ICPT)  

E-Print Network (OSTI)

with type strain genome sequencing projects registered inResearch, Braunschweig) Genome sequencing and annotationthe complete Table 2. Genome sequencing project information

Clum, Alicia

2010-01-01T23:59:59.000Z

180

Genomes containing Duplicates are Hard to compare ... - CECM  

E-Print Network (OSTI)

and other genomic markers are common in genomes, due to several evolutionary . mechanisms, like gene duplication or whole genomes duplications [San01].

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Dissection of Plant Defense Mechanisms Using Chemical and Molecular Genomics  

E-Print Network (OSTI)

of auxins by a chemical genomics approach." Journal ofadvances in chemical genomics." Current Medicinal Chemistrymolecular and chemical genomics." Phytopathology 97(7): S58-

Rodriguez-Salus, Melinda Sue

2012-01-01T23:59:59.000Z

182

Validation in Genomics: CpG Island Methylation Revisited  

E-Print Network (OSTI)

analysis. In: Functional Genomics: Methods and Protocols, M.Segal: Validation in Genomics: CpG Island Methylationpackage and applications to genomics. Bioinformatics and

Segal, Mark R

2006-01-01T23:59:59.000Z

183

Comparative genomics and evolution of eukaryotic phospholipid biosynthesis  

E-Print Network (OSTI)

S. Banfi and B. Franco, Genomics 55 (1999) 68-77. F. Simmer,Comparative genomics and evolution of eukaryoticwork utilizes comparative genomics and phylogenetics for

Lykidis, Athanasios

2006-01-01T23:59:59.000Z

184

Comparative genomics reveals diversity among xanthomonads infecting tomato and pepper  

E-Print Network (OSTI)

Potnis et al. : Comparative genomics reveals diversity amongtomato and pepper. BMC Genomics Submit your next manuscriptpv. syringae Potnis et al. BMC Genomics 2011, 12:146 http://

2011-01-01T23:59:59.000Z

185

Genomics of emerging infectious disease: A PLoS collection.  

E-Print Network (OSTI)

Origins and evolutionary genomics of the 2009 swine-originan Infectious Diseases Genomics Project predict and preventRavel J (2009) The role of genomics in the identification,

Eisen, Jonathan A; MacCallum, Catriona J

2009-01-01T23:59:59.000Z

186

TOPSAN: a collaborative annotation environment for structural genomics.  

E-Print Network (OSTI)

environment for structural genomics Dana Weekes 1 , S Srihigh-throughput structural genomics centers, despite theirbeing determined by structural genomics centers and high-

Weekes, Dana; Krishna, S; Bakolitsa, Constantina; Wilson, Ian A; Godzik, Adam; Wooley, John

2010-01-01T23:59:59.000Z

187

Application of Statistical Methods to Integrative Analysis of Genomic Data  

E-Print Network (OSTI)

in functional genomics . . . . . . . . . . . . . . . . . 1.3throughput technologies in genomics and proteomics promotesElizabeth A. Winzeler. Genomics, gene expression and DNA

Kim, Kyung Pil

2013-01-01T23:59:59.000Z

188

Science Conference Proceedings : About  

Office of Scientific and Technical Information (OSTI)

Science Conference Proceedings - Home Science Conference Proceedings - Home Science Conference Proceedings - About Science Conference Proceedings - Advanced Search Science...

189

D.: Genome halving with an outgroup  

E-Print Network (OSTI)

Abstract: Some genomes are known to have incurred a genome doubling (tetraploidization) event in their evo lutionary history, and this is reflected today in patterns of duplicated segments scattered throughout their chromosomes. These duplications may be used as data to halve the genome, i.e. to reconstruct the an cestral genome at the moment of tetraploidization, but the solution is often highly non- unique. To resolve this problem, we adapt the genome halving algorithm of El-Mabrouk and Sankoff to take account of an external reference genome. We apply this to reconstruct the tetraploid ancestor of maize, using either rice or sorghum as the reference.

Chunfang Zheng; Qian Zhu; David Sankoff

2006-01-01T23:59:59.000Z

190

The Genomes On Line Database (GOLD) in 2007: status of genomic and metagenomic projects and their associated metadata  

E-Print Network (OSTI)

constantly monitoring genome sequencing projects worldwideas part of the Whole Genome Sequencing (WGS) project.large scale microbial genome sequencing programs have been

Liolios, Konstantinos

2008-01-01T23:59:59.000Z

191

The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata  

E-Print Network (OSTI)

large-scale microbial genome sequencing initiatives, e.g. ,in the history of genome sequencing projects: the completedfor publication of genome sequencing projects require the

Liolios, Konstantinos

2010-01-01T23:59:59.000Z

192

DOE Joint Genome Institute: Breaking down cellulose without blasting  

NLE Websites -- All DOE Office Websites (Extended Search)

4, 2011 4, 2011 Breaking down cellulose without blasting lignin: "Dry rot" genome offers lessons for biofuel pretreatment WALNUT CREEK, Calif.-Feared by realtors and homeowners alike, dry rot due to the fungus Serpula lacrymans causes millions of dollars worth of damage to homes and buildings around the world. This brown rot fungus' capacity to break down the cellulose in wood led to its selection for sequencing by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) in 2007, with the goal of identifying the enzymes involved in the degradation process and using the information to improve cellulosic biofuels production. Photo: A variant of Serpula lacrymans causes dry rot. (Dave Brown via Flickr/Creative Commons Attribution 2.0) As reported online July 14 in Science Express, an international team of

193

DOE Joint Genome Institute: DOE JGI Announces 2011 Community Sequencing  

NLE Websites -- All DOE Office Websites (Extended Search)

October 4, 2010 October 4, 2010 Bigger is Better: DOE JGI Announces 2011 Community Sequencing Program Portfolio The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has selected 35 new genomic sequencing projects for its 2011 Community Sequencing Program (CSP)-a targeted sampling of the planet's biodiversity-to be characterized for bioenergy and environmental applications. A sample of CSP 2011 projects *[see photo credits below] Supported by the Office of Biological and Environmental Research in the DOE Office of Science, the DOE JGI's Community Sequencing Program enables scientists from universities and national laboratories around the world to probe the hidden world of microbes and plants for innovative solutions to the nation's major challenges in energy, climate, and environment. This

194

USDA-DOE Make Available $4 Million for Biomass Genomics Research |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

USDA-DOE Make Available $4 Million for Biomass Genomics Research USDA-DOE Make Available $4 Million for Biomass Genomics Research USDA-DOE Make Available $4 Million for Biomass Genomics Research October 12, 2006 - 9:08am Addthis ST. LOUIS, MO -- The U.S. Departments of Energy and Agriculture (DOE and USDA) today announced $4 million for bio-based fuels research that will accelerate the development of alternative fuels. The departments issued a solicitation for research proposals for new plant feedstock genomics research projects. Dr. Raymond L. Orbach, DOE Under Secretary for Science, made the announcement at Advancing Renewable Energy: An American Rural Renaissance, a conference jointly hosted by the two agencies in St. Louis. "We are seeking to accelerate research breakthroughs that contribute towards making biofuels a cost-effective alternative to fossil fuels, with

195

JGI Visiting Scientist Program The DOE Joint Genome Institute Visiting Scientist Program (VSP)  

NLE Websites -- All DOE Office Websites (Extended Search)

Visiting Scientist Program Visiting Scientist Program The DOE Joint Genome Institute Visiting Scientist Program (VSP) provides an opportunity for researchers who are seeking to build upon their line of scientific inquiry by leveraging JGI experimental, computational, and personnel resources for genomic research and sequence-based science. Projects include de novo generation of genome data, assistance in interpreting and/or building on an existing data set, or the refining of new technology (e.g., single-cell genomics; metagenomics, etc.). Length of stay depends on complexity of the project being considered and availability of data and other resources. Investigators, post docs, and graduate students participating in approved JGI User Projects are also invited to apply for on-site access to JGI

196

Development of stable lines of transgenic zebrafish (Danio rerio) to investigate genomic instability  

NLE Websites -- All DOE Office Websites (Extended Search)

stable lines of transgenic zebrafish (Danio rerio) to stable lines of transgenic zebrafish (Danio rerio) to investigate genomic instability Lahcen Jaafar 1 , Wendy W. Kuhne 2 , Xiayang Xie 3 , Xuan Zheng 1,4 , Jeffrey S. Mumm 3 , and William S. Dynan 1 1 Institute of Molecular Medicine and Genetics, Georgia Health Sciences University, Georgia 30912, USA, 2 Savannah River National Laboratory, Aiken SC 29808, 3 Department of Cellular Biology and Anatomy, Georgia Health Sciences University, Georgia 30912, USA, 4 Genetic Diagnosis Center, Zhongnan Hospital of Wuhan University, Wuhan, China The goal of our project is to investigate low-dose radiation induced-genomic instability. We describe the development of a whole-vertebrate model bearing a reporter transgene that is designed to indicate the presence of genome instability by somatic homologous

197

Energy Department Awards $92 Million for Genomics Research | U.S. DOE  

NLE Websites -- All DOE Office Websites (Extended Search)

Energy Energy Department Awards $92 Million for Genomics Research News Featured Articles Science Headlines 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Presentations & Testimony News Archives Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 10.03.05 Energy Department Awards $92 Million for Genomics Research Print Text Size: A A A Subscribe FeedbackShare Page WASHINGTON, DC - The Department of Energy (DOE) today issued a comprehensive plan for a new generation of biology research that builds on genome project investments to help solve national energy and environmental challenges. Microbial enzymes could, for example, be used to improve the manufacture of ethanol from cellulose by replacing the inefficient and

198

Faculty of Science General Science  

E-Print Network (OSTI)

Faculty of Science General Science The General Science program gives you maximum flexibility to explore the sciences, plus the core requirements you need for on-going, specialized studies. www.uwindsor.ca/science Rigorous, Enriching Programs The BSc General Science program is a great way to explore your many interests

199

Wine Science Wine Sciencee Science  

E-Print Network (OSTI)

Wine Science Wine Sciencee Science Thomas Henick-Kling Professor of Enology Director of Viticulture & Enology Program #12;Wine Science Wine Science Growth of Washington Wine Industry #12;Wine Science Wine Science Wine Grapes utilized 2007 2008 2009 2010 WA 127,000 145,000 156,000 160,000 NY 24,000 26,000 30

200

Stepping Up the Pace of Discovery: the Genomes to Life Program  

Science Conference Proceedings (OSTI)

Genomes to Life (GTL), the U.S. Department ofEnergy Office of Science's systems biology program,focuses on environmental microbiology. Over the next 10to 20 years, GTL's key goal is to understand the lifeprocesses of thousands of microbes and microbial ...

Marvin Frazier; David Thomassen; Aristides Patrinos; Gary Johnson; Carl E. Oliver; Edward Uberbacher

2003-08-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Genomic Analysis of Burkholderia And Rhodococcus equi Bacteriophages  

E-Print Network (OSTI)

Recently there has been an increase in bacterial infections that are resistant to traditional antibiotics. With this upward trend of resistance, many scientists are turning to alternative treatments like phage therapeutics. In this report there is discussion of isolating and characterizing novel phages of Rhodococcus equi and Burkholderia cenocepacia. Burkholderia cenocepacia is part of the Burkholderia cepacia complex (BCC), which causes pulmonary infections in cystic fibrosis patients (10). Rhodococcus equi is an intracellular pathogen which invades the macrophages of immunocompromised individuals such as young foals. While phylogenetically R. equi, a Gram-positive bacterium, and Burkholderia, Gram-negative bacteria, are unrelated, they both occupy the same ecological niche as soil saprophytes. Therefore, it is possible to isolate novel phages from the soil for both of these bacteria. Using a soil enrichment procedure, it has been possible to isolate and amplify 12 novel R. equi bacteriophages. These bacteriophages all appear to have the same morphologies as siphophages and similar genome sizes. Five of the R. equi phage genomes were pooled together with iv other bacteriophages and pyrosequenced using 454 LifeSciences Technology. These phages are mosaic and sequencing traditional plasmid libraries were sufficient to deconvolute the 454 data. Also reported is the complete genomic sequencing of BcepNY3, a Burkholderia cenocepacia bacteriophage via a Whole Genome Shotgun Approach. BcepNY3s 47,382 bp genome was found to encode 70 proteins and 1 tRNA. It was determined that BcepNY3 is part of the previously described Bcep781 family of phages (26). Surprisingly, it is also related to the Xanthomonas oryzae phage OP2, and proposed in this report is a possible evolutionary connection between OP2 and the Bcep781 family of phages.

Orchard II, Robert C.

2011-08-04T23:59:59.000Z

202

Materials Genome: CALPHAD, ESPEI, and Beyond  

Science Conference Proceedings (OSTI)

Materials Genomics Past & Future: From CALPHAD to Flight Modelling the Properties of Multi-Component Commercial Alloys Molecular Dynamics...

203

April 20, 2012 NIST Genomes in a Bottle Workshop ...  

Science Conference Proceedings (OSTI)

... discussed the Archon Genomics XPrize work characterizing genomes and validating pipelines, Ryan Poplin discussed Broad's pipeline to analyze ...

2012-10-04T23:59:59.000Z

204

Nuclear Organization and Genome Function  

E-Print Network (OSTI)

Nuclear Organization and Genome Function Kevin Van Bortle and Victor G. Corces Department-range interactions and have proposed roles in nuclear organization. In this review, we explore recent findings for the roles of insulators in nuclear organization. 163 Annu.Rev.CellDev.Biol.2012.28:163-187.Downloadedfromwww

Corces, Victor G.

205

Robust classifying of prokaryotic genomes  

Science Conference Proceedings (OSTI)

In this paper, we propose a method to classify prokaryotic genomes using the agglomerative information bottleneck method for unsupervised clustering. Although the method we present here is closely related to a group of methods based on detecting the ... Keywords: Agglomerative clustering, COGs, Gene length, IB, Information bottleneck method, Jackknifing, NJ, Phylogenomics, UPGMA

Katerina Korenblat; Zeev Volkovich; Alexander Bolshoy

2012-10-01T23:59:59.000Z

206

Genomes and evolution Editorial overview  

E-Print Network (OSTI)

. co/i is true for the elephant", asserted Jacques Monod [l] during the heroic age of molecular biology-effective strategy to develop genome sequencing infrastructure as well as to provide grist for biologists' mills and illustrates the utility of studying things in pairs. These two species are highly divergent evolutionarily

Boguski, Mark S.

207

Is sustainability science really a science?  

NLE Websites -- All DOE Office Websites (Extended Search)

Is sustainability science really a science? Is sustainability science really a science? The team's work shows that although sustainability science has been growing explosively...

208

Whole genome sequencing and comparative genomic analyses of two Vibrio cholerae O139 Bengal-specific Podoviruses to other N4-like phages reveal extensive genetic diversity  

E-Print Network (OSTI)

Chen YJ, Chen Z, et al: Genome sequencing in microfabricatedas: Fouts et al. : Whole genome sequencing and comparativeOpen Access Whole genome sequencing and comparative genomic

2013-01-01T23:59:59.000Z

209

Science Education ProgramScience Education Program TEACH SCIENCE  

E-Print Network (OSTI)

Science Education ProgramScience Education Program TEACH SCIENCE IMPACT THE FUTURE #12;Science Education ProgramScience Education Program Why Teach Science? #12;Science Education Program SCIENCE, a middle school science teacher. He teaches several grades and covers many science topics, covering

de Lijser, Peter

210

Information Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Information Science Information Science1354608000000Information ScienceSome of these resources are LANL-only and will require Remote Access.NoQuestions? 667-5809library@lanl.gov...

211

The ecoresponsive genome of Daphnia pulex  

Science Conference Proceedings (OSTI)

This document provides supporting material related to the sequencing of the ecoresponsive genome of Daphnia pulex. This material includes information on materials and methods and supporting text, as well as supplemental figures, tables, and references. The coverage of materials and methods addresses genome sequence, assembly, and mapping to chromosomes, gene inventory, attributes of a compact genome, the origin and preservation of Daphnia pulex genes, implications of Daphnia's genome structure, evolutionary diversification of duplicated genes, functional significance of expanded gene families, and ecoresponsive genes. Supporting text covers chromosome studies, gene homology among Daphnia genomes, micro-RNA and transposable elements and the 46 Daphnia pulex opsins. 36 figures, 50 tables, 183 references.

Colbourne, John K.; Pfrender, Michael E.; Gilbert, Donald; Thomas, W. Kelley; Tucker, Abraham; Oakley, Todd H.; Tokishita, Shinichi; Aerts, Andrea; Arnold, Georg J.; Basu, Malay Kumar; Bauer, Darren J.; Caceres, Carla E.; Carmel, Liran; Casola, Claudio; Choi, Jeong-Hyeon; Detter, John C.; Dong, Qunfeng; Dusheyko, Serge; Eads, Brian D.; Frohlich, Thomas; Geiler-Samerotte, Kerry A.; Gerlach, Daniel; Hatcher, Phil; Jogdeo, Sanjuro; Krijgsveld, Jeroen; Kriventseva, Evgenia V; Kltz, Dietmar; Laforsch, Christian; Lindquist, Erika; Lopez, Jacqueline; Manak, Robert; Muller, Jean; Pangilinan, Jasmyn; Patwardhan, Rupali P.; Pitluck, Samuel; Pritham, Ellen J.; Rechtsteiner, Andreas; Rho, Mina; Rogozin, Igor B.; Sakarya, Onur; Salamov, Asaf; Schaack, Sarah; Shapiro, Harris; Shiga, Yasuhiro; Skalitzky, Courtney; Smith, Zachary; Souvorov, Alexander; Sung, Way; Tang, Zuojian; Tsuchiya, Dai; Tu, Hank; Vos, Harmjan; Wang, Mei; Wolf, Yuri I.; Yamagata, Hideo; Yamada, Takuji; Ye, Yuzhen; Shaw, Joseph R.; Andrews, Justen; Crease, Teresa J.; Tang, Haixu; Lucas, Susan M.; Robertson, Hugh M.; Bork, Peer; Koonin, Eugene V.; Zdobnov, Evgeny M.; Grigoriev, Igor V.; Lynch, Michael; Boore, Jeffrey L.

2011-02-04T23:59:59.000Z

212

DOE Joint Genome Institute: Genome of Simplest Animal Reveals Ancient  

NLE Websites -- All DOE Office Websites (Extended Search)

21, 2008 21, 2008 Genome of Simplest Animal Reveals Ancient Lineage, Confounding Array of Complex Capabilities WALNUT CREEK, CA-As Aesop said, appearances are deceiving-even in life's tiniest critters. From first detection in the 1880s, clinging to the sides of an aquarium, to its recent characterization by the U.S. Department of Energy Joint Genome Institute (DOE JGI), a simple and primitive animal, Trichoplax adhaerens, appears to harbor a far more complex suite of capabilities than meets the eye. The findings, reported in the August 21 online edition of the journal Nature, establish a group of organisms as a branching point of animal evolution and identify sets of genes, or a "parts list," employed by organisms that have evolved along particular branches.

213

Sequencing Intractable DNA to Close Microbial Genomes  

Science Conference Proceedings (OSTI)

Advancement in high throughput DNA sequencing technologies has supported a rapid proliferation of microbial genome sequencing projects, providing the genetic blueprint for for in-depth studies. Oftentimes, difficult to sequence regions in microbial genomes are ruled intractable resulting in a growing number of genomes with sequence gaps deposited in databases. A procedure was developed to sequence such difficult regions in the non-contiguous finished Desulfovibrio desulfuricans ND132 genome (6 intractable gaps) and the Desulfovibrio africanus genome (1 intractable gap). The polynucleotides surrounding each gap formed GC rich secondary structures making the regions refractory to amplification and sequencing. Strand-displacing DNA polymerases used in concert with a novel ramped PCR extension cycle supported amplification and closure of all gap regions in both genomes. These developed procedures support accurate gene annotation, and provide a step-wise method that reduces the effort required for genome finishing.

Hurt, Jr., Richard Ashley [ORNL; Brown, Steven D [ORNL; Podar, Mircea [ORNL; Palumbo, Anthony Vito [ORNL; Elias, Dwayne A [ORNL

2012-01-01T23:59:59.000Z

214

Insights from Human/Mouse genome comparisons  

SciTech Connect

Large-scale public genomic sequencing efforts have provided a wealth of vertebrate sequence data poised to provide insights into mammalian biology. These include deep genomic sequence coverage of human, mouse, rat, zebrafish, and two pufferfish (Fugu rubripes and Tetraodon nigroviridis) (Aparicio et al. 2002; Lander et al. 2001; Venter et al. 2001; Waterston et al. 2002). In addition, a high-priority has been placed on determining the genomic sequence of chimpanzee, dog, cow, frog, and chicken (Boguski 2002). While only recently available, whole genome sequence data have provided the unique opportunity to globally compare complete genome contents. Furthermore, the shared evolutionary ancestry of vertebrate species has allowed the development of comparative genomic approaches to identify ancient conserved sequences with functionality. Accordingly, this review focuses on the initial comparison of available mammalian genomes and describes various insights derived from such analysis.

Pennacchio, Len A.

2003-03-30T23:59:59.000Z

215

Science Highlights  

NLE Websites -- All DOE Office Websites (Extended Search)

Science Highlights Print Science Highlights Featured scientific research based on publications resulting from work done at the ALS. Highlights are nominated by management and...

216

Science Organizations  

NLE Websites -- All DOE Office Websites (Extended Search)

Organizations Science Organizations National security depends on science and technology. The United States relies on Los Alamos National Laboratory for the best of both. No place...

217

Science Requirements  

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Science Requirements About ESnet Overview ESnet Staff Governance Our Network Case Studies ESnet Strategic Plan ESnet Organizational Chart ESnet History Science Requirements Network...

218

Computer Science  

NLE Websites -- All DOE Office Websites (Extended Search)

in Physics, Mathematics, Computer Science, Quantitative Biology, Quantitative Finance and Statistics Cite Seer Department of Energy provided open access science research citations...

219

Science & Innovation  

NLE Websites -- All DOE Office Websites (Extended Search)

National Laboratory for the best of both. No place on Earth pursues a broader array of world-class scientific endeavors. Faces of Science Science & Engineering Capabilities...

220

Life sciences: Lawrence Berkeley Laboratory, 1988  

SciTech Connect

Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program laboratory has emerged, in which the life sciences participate as a full partner. The LBL Human Genome Center is a contribution to the growing international effort to map the human genome. Its achievements represent LBL divisions, including Engineering, Materials and Chemical Sciences, and Information and Computing Sciences, along with Cell and Molecular Biology and Chemical Biodynamics. The Advanced Light Source Life Sciences Center will comprise not only beamlines and experimental end stations, but also supporting laboratories and office space for scientists from across the US. This effort reflects a confluence of scientific disciplines --- this time represented by individuals from the life sciences divisions and by engineers and physicists associated with the Advanced Light Source project. And finally, this report itself, the first summarizing the efforts of all four life sciences divisions, suggests a new spirit of cooperation. 30 figs.

1989-07-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Life sciences: Lawrence Berkeley Laboratory, 1988  

DOE Green Energy (OSTI)

Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program laboratory has emerged, in which the life sciences participate as a full partner. The LBL Human Genome Center is a contribution to the growing international effort to map the human genome. Its achievements represent LBL divisions, including Engineering, Materials and Chemical Sciences, and Information and Computing Sciences, along with Cell and Molecular Biology and Chemical Biodynamics. The Advanced Light Source Life Sciences Center will comprise not only beamlines and experimental end stations, but also supporting laboratories and office space for scientists from across the US. This effort reflects a confluence of scientific disciplines --- this time represented by individuals from the life sciences divisions and by engineers and physicists associated with the Advanced Light Source project. And finally, this report itself, the first summarizing the efforts of all four life sciences divisions, suggests a new spirit of cooperation. 30 figs.

Not Available

1989-07-01T23:59:59.000Z

222

Science | ORNL Neutron Sciences  

NLE Websites -- All DOE Office Websites (Extended Search)

Neutron Science Neutron Science Neutron Scattering Science Neutrons are one of the fundamental particles that make up matter and have properties that make them ideal for certain types of research. In the universe, neutrons are abundant, making up more than half of all visible matter. Neutron scattering provides information about the positions, motions, and magnetic properties of solids. When a beam of neutrons is aimed at a sample, many neutrons will pass through the material. But some will interact directly with atomic nuclei and "bounce" away at an angle, like colliding balls in a game of pool. This behavior is called neutron diffraction, or neutron scattering. Using detectors, scientists can count scattered neutrons, measure their energies and the angles at which they scatter, and map their final position

223

Genome Improvement at JGI-HAGSC  

Science Conference Proceedings (OSTI)

Since the completion of the sequencing of the human genome, the JGI has rapidly expanded its scientific goals in several DOE mission-relevant areas. At the JGI-HAGSC, we have kept pace with this rapid expansion of projects with our focus on assessing, assembling, improving and finishing eukaryotic whole genome shotgun (WGS) projects for which the shotgun sequence is generated at the Production Genomic Facility (JGI-PGF). We follow this by combining the draft WGS with genomic resources generated at JGI-HAGSC or in collaborator laboratories (including BAC end sequences, genetic maps and FLcDNA sequences) to produce an improved draft sequence. For eukaryotic genomes important to the DOE mission, we then add further information from directed experiments to produce reference genomic sequences that are publicly available for any scientific researcher. Also, we have continued our program for producing BAC-based finished sequence, both for adding information to JGI genome projects and for small BAC-based sequencing projects proposed through any of the JGI sequencing programs. We have now built our computational expertise in WGS assembly and analysis and have moved eukaryotic genome assembly from the JGI-PGF to JGI-HAGSC. We have concentrated our assembly development work on large plant genomes and complex fungal and algal genomes.

Grimwood, Jane: Schmutz, Jeremy, J.: Myers, Richard, M.

2012-03-03T23:59:59.000Z

224

Building Science  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Science Science The "Enclosure" Joseph Lstiburek, Ph.D., P.Eng, ASHRAE Fellow www.buildingscience.com * Control heat flow * Control airflow * Control water vapor flow * Control rain * Control ground water * Control light and solar radiation * Control noise and vibrations * Control contaminants, environmental hazards and odors * Control insects, rodents and vermin * Control fire * Provide strength and rigidity * Be durable * Be aesthetically pleasing * Be economical Building Science Corporation Joseph Lstiburek 2 Water Control Layer Air Control Layer Vapor Control Layer Thermal Control Layer Building Science Corporation Joseph Lstiburek 3 Building Science Corporation Joseph Lstiburek 4 Building Science Corporation Joseph Lstiburek 5 Building Science Corporation

225

PNNL: Biological Sciences: Frontiers in Biological Sciences Seminar Series  

NLE Websites -- All DOE Office Websites (Extended Search)

Frontiers in Biological Sciences Frontiers in Biological Sciences The seminar series features nationally/internationally known researchers from industry, government, and academia discussing novel ideas and advancements related to biological sciences. The hour-long seminars will feature a 45-minute talk by the featured speaker followed by 15 minutes of discussion with the audience members. 2014 Tim Donohue Timothy J. Donohue, Ph.D. Timothy J. Donohue, Ph.D. Department of Bacteriology University of Wisconsin-Madison Director, Great Lakes Bioenergy Research Center Tuesday, January 14, 2014 EMSL Auditorium 11:00 a.m. Biological Insights and Products Gleaned from Mining Bacterial Genomes and Pathways Professor Donohue has been a member of the UW-Madison Bacteriology Department since 1986. His research program studies bacterial energy

226

In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing  

E-Print Network (OSTI)

Yeung G, et al: Human genome sequencing using unchained basecell line using whole genome sequencing. BMC Genomics 2012cell line using whole genome sequencing Dorothee Nickles 1 ,

2012-01-01T23:59:59.000Z

227

Complete genome sequence of Sanguibacter keddieii type strain (ST-74T)  

E-Print Network (OSTI)

60%. Strains with a genome sequencing project registered inacknowledgements. Genome sequencing Genome project historyin Table 2. Table 2. Genome sequencing project information

Ivanova, Natalia

2010-01-01T23:59:59.000Z

228

The Pinus taeda genome is characterized by diverse and highly diverged repetitive sequences  

E-Print Network (OSTI)

deep transcriptome or genome sequencing, as well as experi-Three sets of whole genome shotgun sequencing were performedthroughput Whole Genome Shotgun Sequencing genomic DNA at a

2010-01-01T23:59:59.000Z

229

Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460T)  

E-Print Network (OSTI)

of the complete genome sequencing and annotation. Figure 160%. Strains with a genome sequencing project registered inexamined to date. Genome sequencing and annotation Genome

Kiss, Hajnalka

2010-01-01T23:59:59.000Z

230

Complete genome sequence of Beutenbergia cavernae type strain (HKI 0122T)  

E-Print Network (OSTI)

of the complete genome sequencing and annotation. In60%. Strains with a genome-sequencing project regis- tered8] and the complete Genome sequencing and annotation Genome

Land, Miriam

2010-01-01T23:59:59.000Z

231

Plethodontid salamander mitochondrial genomics: A parsimony evaluation of character conflict and implications for historical biogeography  

E-Print Network (OSTI)

Mitochondrial DNA; Genomics; Biogeography; Appalachia. 1.salamander mitochondrial genomics: A parsimony evaluation of1,2 Department of Evolutionary Genomics, DOE Joint Genome

Macey, J. Robert

2005-01-01T23:59:59.000Z

232

History of the DOE Human Genome Program  

Office of Scientific and Technical Information (OSTI)

History of the DOE Human Genome Program History of the DOE Human Genome Program The following history is taken from the U.S. Department of Energy 1991-91 Human Genome Program Report (June 1992). This is an archived item. A brief history of the U.S. Department of Energy (DOE) Human Genome Program will be useful in a discussion of the objectives of the DOE program as well as those of the collaborative U.S. Human Genome Project. The Office of Health and Environmental Research (OHER) of DOE and its predecessor agencies--the Atomic Energy Commission and the Energy Research and Development Administration--have long sponsored research into genetics, both in microbial systems and in mammals, including basic studies on genome structure, replication, damage, and repair and the consequences of genetic

233

Faculty of Science Computer Science  

E-Print Network (OSTI)

Faculty of Science Computer Science Computer software engineering, network and system analysis.uwindsor.ca/computerscience The University of Windsor offers a variety of computer science programs to prepare students for a career in the technology industry or in research and academia. A computer science degree provides an in-depth understanding

234

DOE Joint Genome Institute: JGI & NERSC Partner for GenomicHigh...  

NLE Websites -- All DOE Office Websites (Extended Search)

April 12, 2010 JGI & NERSC Partner for Genomic High-performance Computing WALNUT CREEK, CA-The Department of Energy Joint Genome Institute (JGI) and the National Energy Research...

235

Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

Science Conference Proceedings (OSTI)

Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

Zimmer, Carl [New York Times

2012-03-20T23:59:59.000Z

236

NIST and The Materials Genome Initiative  

Science Conference Proceedings (OSTI)

... the Materials Genome Ini(a(ve formed (NIST, DOE, DOD, NSF, NASA, NIH, USGS, NNSA, DARPA, NSA, OMB) 6/12: MGI White House Kickoff Event ...

2013-07-02T23:59:59.000Z

237

Fueling the Future with Fungal Genomics  

E-Print Network (OSTI)

genome sequencing and bioenergy. Fungal Biology Reviews. 22:of fungal pathogens of bioenergy crops with sequenced hostand improve them to make bioenergy production efficient on

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

238

Today, DOE's Joint Genome Institute (a  

NLE Websites -- All DOE Office Websites (Extended Search)

characterizing the basic principles and relationships underlying living systems. Social Impact: Armed with the DNA sequence of the human genome, scientists will be able to...

239

Synthetic Genomics Inc | Open Energy Information  

Open Energy Info (EERE)

search Name Synthetic Genomics Inc. Place La Jolla, California Sector Hydro, Hydrogen, Renewable Energy Product California-based company planning to create new types of...

240

ICME Successes: From Genome to Flight  

Science Conference Proceedings (OSTI)

Past success defines a clear path forward for major enhancement of materials genomics technology. Proceedings Inclusion? Definite: A combination print-CD...

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Genomics Division: How to Contact Us  

NLE Websites -- All DOE Office Websites (Extended Search)

How to Contact Us Please contact: Mary Miller, Senior Administrator Genomics Division Lawrence Berkeley National Laboratory 1 Cyclotron Road, Mailstop 84-171 Berkeley, CA 94720...

242

CI Announces Globus Genomics | Argonne National Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

CI Announces Globus Genomics April 9, 2013 Tweet EmailPrint The ArgonneUniversity of Chicago Computation Institute has announced a new sequencing analysis service called Globus...

243

DOE Joint Genome Institute 2008 Progress Report  

E-Print Network (OSTI)

Paterson, A. , et al. The Sorghum bicolor genome and thethe 730-million nucleotide Sorghum bicolor sequence, and thesoybean, eucalyp- tus, sorghum, foxtail millet, cassava,

Gilbert, David

2009-01-01T23:59:59.000Z

244

DOE Joint Genome Institute 2008 Progress Report  

E-Print Network (OSTI)

proteins for biofuel production. Trends in Mi- crobiology,could help improve biofuel production. Diatom Genome Helpsa key target. Current biofuel production meth- ods, such as

Gilbert, David

2009-01-01T23:59:59.000Z

245

DOE JGI Releases Soybean Genome Assembly  

NLE Websites -- All DOE Office Websites (Extended Search)

SoyMap team, comprising principal investigator Scott Jackson, Gary Stacey and Henry Nguyen, Jeff Doyle of Cornell University, William Beavis of the National Center for Genome...

246

When is Reproducibility an Ethical Issue? Genomics ...  

Science Conference Proceedings (OSTI)

... Genomics, personalized medicine, and human error. ... Dr. Baggerly will present several case studies where simple errors may have put patients at risk ...

2013-03-20T23:59:59.000Z

247

ORNL Genome Analysis Pipeline - Yeast (Saccharomyces cerevisiae...  

NLE Websites -- All DOE Office Websites (Extended Search)

Grail (Microbial Gene Prediction System Internet Link) GrailEXP Genome Analysis Pipeline DomainParser PROSPECT (PROtein Structure Prediction and Evaluation Computer Toolkit)...

248

Science Projects  

NLE Websites -- All DOE Office Websites (Extended Search)

Argonne Argonne Science Project Ideas! Our Science Project section provides you with sample classroom projects and experiments, online aids for learning about science, as well as ideas for Science Fair Projects. Please select any project below to continue. Also, if you have an idea for a great project or experiment that we could share, please click our Ideas page. We would love to hear from you! Science Fair Ideas Science Fair Ideas! The best ideas for science projects are learning about and investigating something in science that interests you. NEWTON has a list of Science Fair linkd that can help you find the right topic. Toothpick Bridge Web Sites Toothpick Bridge Sites! Building a toothpick bridge is a great class project for physics and engineering students. Here are some sites that we recommend to get you started!

249

About | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

About About Biological and Environmental Research (BER) BER Home About Staff Organization Chart .pdf file (172KB) BER Budget BER Committees of Visitors Directions Jobs Research Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301) 903-5051 E: sc.ber@science.doe.gov More Information » About Print Text Size: A A A RSS Feeds FeedbackShare Page BER's scientific impact has been transformative. In 1986, the Human Genome Project gave birth to modern biotechnology and genomics-based systems biology. Today, with its Genomic Sciences Program and the DOE Joint

250

Materials Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Materials Science Materials Science Materials Science1354608000000Materials ScienceSome of these resources are LANL-only and will require Remote Access./No/Questions? 667-5809library@lanl.gov Materials Science Some of these resources are LANL-only and will require Remote Access. Key Resources Data Sources Reference Organizations Journals Key Resources CINDAS Materials Property Databases video icon Thermophysical Properties of Matter Database (TPMD) Aerospace Structural Metals Database (ASMD) Damage Tolerant Design Handbook (DTDH) Microelectronics Packaging Materials Database (MPMD) Structural Alloys Handbook (SAH) Proquest Technology Collection Includes the Materials Science collection MRS Online Proceedings Library Papers presented at meetings of the Materials Research Society Data Sources

251

NREL: Energy Sciences - Larry Taylor  

NLE Websites -- All DOE Office Websites (Extended Search)

Larry Taylor Larry Taylor Research Scientist Phone: (303) 384-7784 Email: larry.taylor@nrel.gov At NREL Since: 2007 Larry Taylor received his Ph.D. in Environmental Molecular Biology and Biotechnology from the Marine and Estuarine Environmental Sciences department at the University of Maryland, College Park. His dissertation work focused on the functional genomics of the plant cell wall degrading enzyme systems of the marine bacterium Saccharophagus degradans 2-40, which was isolated from decaying salt marsh grass the Chesapeake Bay watershed in 1988. Preliminary genomic analyses revealed that the S. degradans encodes more than 180 predicted carbohydrases. Under the direction of Prof. Ronald M. Weiner, and in collaboration with Dr. Bernard Henrisaat, Dr. Taylor identified the predicted cellulase system of S. degradans through sequence

252

ComBo : a visualization tool for comparative genomic data  

E-Print Network (OSTI)

Propelled by advances in sequencing technology, the advent of the genomic era brings the challenge of managing and interpreting massive amount of genomic data. A number of single-genome browsers have been developed for ...

Yu, Tamara H. (Tamara Hui)

2004-01-01T23:59:59.000Z

253

Evolutionary Genomics of Life in (and from) the Sea  

E-Print Network (OSTI)

291: 1304-1351. Table 1. Genomics information on the webLBNL-59356 Evolutionary Genomics of Life in (and from) thean engine for comparative genomics. The six largest centers

Boore, Jeffrey L.

2009-01-01T23:59:59.000Z

254

Structural Genomics of Minimal Organisms: Pipeline and Results  

E-Print Network (OSTI)

of recombinant proteins. J. Struct. Funct. Genomics 5:69-74.proteins. J. Struct. Funct. Genomics 5:69-74. Oganesyan,Structural Genomics of Minimal Organisms: Pipeline and

Kim, Sung-Hou

2008-01-01T23:59:59.000Z

255

The Impact of Structural Genomics: Expectations and Outcomes  

E-Print Network (OSTI)

Choi et al. , J Struct Funct Genomics 4, 31-4 (2003). H. M.Center for Structural Genomics, sequence families of unknownMCSG) Northeast Structural Genomics Consortium, Novel folds

Chandonia, John-Marc; Brenner, Steven E.

2005-01-01T23:59:59.000Z

256

Comparative genomics reveals evidence of marine adaptation in Salinispora species.  

E-Print Network (OSTI)

Orcutt B, et al: Ecological genomics of marine roseobacters.1037-1042. Penn and Jensen BMC Genomics 2012, 13:86 http://and Jensen: Comparative genomics reveals evidence of marine

Penn, Kevin; Jensen, Paul R

2012-01-01T23:59:59.000Z

257

Target Selection and Deselection at the Berkeley Structural Genomics Center  

E-Print Network (OSTI)

gene-set concept. Annu Rev Genomics Hum Genet 2000;1:99-116.SE. A tour of structural genomics. Nat Rev Genet 2001;2(10):M, Wang LK. Structural genomics: a pipeline for providing

Chandonia, John-Marc; Kim, Sung-Hou; Brenner, Steven E.

2005-01-01T23:59:59.000Z

258

Phytozome: A Comparative Platform for Green Plant Genomics  

E-Print Network (OSTI)

a growing plant comparative genomics resource. Nucleic AcidsL.A. (2011) The Sol Genomics Network (solgenomics.net):for comparative plant genomics. Nucleic Acids Res, 36, D959-

Goodstein, David M.

2012-01-01T23:59:59.000Z

259

UV Decontamination of MDA Reagents for Single Cell Genomics  

E-Print Network (OSTI)

Reagents for Single Cell Genomics Janey Lee 1* , Damon TigheReagents for Single Cell Genomics Janey Lee 1 , Damon TigheAbstract Single cell genomics, the amplification and

Lee, Janey

2011-01-01T23:59:59.000Z

260

Biological and Environmental Research (BER) Homepage | U.S. DOE Office of  

Office of Science (SC) Website

BER Home BER Home Biological and Environmental Research (BER) BER Home About Research Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301) 903-5051 E: sc.ber@science.doe.gov More Information » BER Accomplishments BSSD / CESD Timeline Take an interactive look at a century of scientific accomplishments in BER's Climate and Environmental Sciences / Biological Systems Science DivisionsRead More BER Interactive Accomplishments Timeline Understanding Complex Biological and Environmental Systems

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

EMSL: Science  

NLE Websites -- All DOE Office Websites (Extended Search)

EMSL's Science and Science Themes EMSL's Science and Science Themes EMSL's unique and state-of-the-art capabilities along with staff expertise can help scientists gain a predictive understanding of the molecular-to-mesoscale processes in climate, biological, environmental and energy systems. These advancements are critical to development of sustainable solutions to the nation's energy and environmental challenges. Four Science Themes help EMSL define and direct the research investments and establish a portfolio of user projects to accelerate scientific innovation and discovery in the areas of environmental molecular science critical to DOE and the nation. EMSL's annual call for proposals solicits proposals on specific topics within these Science Themes. Over the next 10 years, EMSL will focus its science toward developing

262

Scientists Launch the Genomic Encyclopedia of Bacteria and Archaea | U.S.  

NLE Websites -- All DOE Office Websites (Extended Search)

Scientists Scientists Launch the Genomic Encyclopedia of Bacteria and Archaea News Featured Articles 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Science Headlines Presentations & Testimony News Archives Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 12.28.09 Scientists Launch the Genomic Encyclopedia of Bacteria and Archaea Unlocking the diversity of microbial communities may benefit biofuel production, global carbon storage, and bioremediation. Print Text Size: A A A Subscribe FeedbackShare Page Scientists estimate that there are approximately 4 × 10^30 microbes living on the planet. To put this number into perspective, there are 4,000,000,000,000,000,000,000,000,000,000 microbes living on the planet

263

Nuclear Sciences | More Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Chemistry Chemistry Advanced Materials Nuclear Forensics Climate & Environment Biology and Soft Matter Chemical and Engineering Materials Quantum Condensed Matter Computational Chemistry Nuclear Sciences More Science Home | Science & Discovery | More Science | Chemistry | Nuclear Sciences SHARE Nuclear Sciences In World War II's Manhattan Project, ORNL helped usher in the nuclear age. Today, laboratory scientists are leaders in using nuclear technologies and systems to improve human health; explore safer, more environmentally friendly power; and better understand the structure of matter. Thanks to its nuclear heritage, ORNL is a world leader in the production of isotopes for medical purposes and research. The lab's High Flux Isotope Reactor (HFIR) and Radiochemical Engineering Development Center (REDC)

264

Materials Science  

Science Conference Proceedings (OSTI)

Materials Science. Summary: Key metrologies/systems: In situ spectroscopic ellipsometry, linear and non-linear spectroscopies ...

2012-10-02T23:59:59.000Z

265

Uses of antimicrobial genes from microbial genome  

DOE Patents (OSTI)

We describe a method for mining microbial genomes to discover antimicrobial genes and proteins having broad spectrum of activity. Also described are antimicrobial genes and their expression products from various microbial genomes that were found using this method. The products of such genes can be used as antimicrobial agents or as tools for molecular biology.

Sorek, Rotem; Rubin, Edward M.

2013-08-20T23:59:59.000Z

266

DOE Joint Genome Institute: Peach Genome Offers Insights into Breeding  

NLE Websites -- All DOE Office Websites (Extended Search)

March 24, 2013 March 24, 2013 Peach Genome Offers Insights into Breeding Strategies for Biofuels Crops Rapidly growing trees like poplars and willows are candidate "biofuel crops" from which it is expected that cellulosic ethanol and higher energy content fuels can be efficiently extracted. Domesticating these crops requires a deep understanding of the physiology and genetics of trees, and scientists are turning to long-domesticated fruit trees for hints. The relationship between a peach and a poplar may not be obvious at first glance, but to botanists both trees are part of the rosid superfamily, which includes not only fruit crops like apples, strawberries, cherries, and almonds, but many other plants as well, including rose that gives the superfamily its name.

267

Whole Genome Duplications, Multi-Break Rearrangements, and Genome Halving Theorem  

E-Print Network (OSTI)

The Genome Halving Problem, motivated by the whole genome duplication events in molecular evolution, was solved by El-Mabrouk and Sankoff. The El-Mabrouk Sankoff algorithm is rather complex inspiring a quest for a simpler solution. An alternative approach to Genome Halving Problem based on the notion of the contracted breakpoint graph was recently proposed in [2]. This new technique reveals that while the El-MabroukSankoff result is correct in most cases, it does not hold in the case of unichromosomal genomes. This raises a problem of correcting El-MabroukSankoff analysis and devising an algorithm that deals adequately with all genomes. In this paper we efficiently classify all genomes into two classes and show that while the El-MabroukSankoff theorem holds for the first class, it is incorrect for the second class. The crux of our analysis is a new combinatorial invariant defined on duplicated permutations. Using this invariant we were able to come up with a full proof of the Genome Halving theorem and a polynomial algorithm for Genome Halving Problem (for unichromosomal genomes). We also give the first short proof of the original El-MabroukSankoff result for multichromosomal genomes. Finally, we discuss a generalization of Genome Halving Problem for a more general set of rearrangement operations (including transpositions) and propose an efficient algorithm for solving this problem. 1

Max A. Alekseyev; Pavel A. Pevzner

2007-01-01T23:59:59.000Z

268

The Arabidopsis lyrata genome sequence and the basis of rapid genome size change  

Science Conference Proceedings (OSTI)

In our manuscript, we present a high-quality genome sequence of the Arabidopsis thaliana relative, Arabidopsis lyrata, produced by dideoxy sequencing. We have performed the usual types of genome analysis (gene annotation, dN/dS studies etc. etc.), but this is relegated to the Supporting Information. Instead, we focus on what was a major motivation for sequencing this genome, namely to understand how A. thaliana lost half its genome in a few million years and lived to tell the tale. The rather surprising conclusion is that there is not a single genomic feature that accounts for the reduced genome, but that every aspect centromeres, intergenic regions, transposable elements, gene family number is affected through hundreds of thousands of cuts. This strongly suggests that overall genome size in itself is what has been under selection, a suggestion that is strongly supported by our demonstration (using population genetics data from A. thaliana) that new deletions seem to be driven to fixation.

Hu, Tina T.; Pattyn, Pedro; Bakker, Erica G.; Cao, Jun; Cheng, Jan-Fang; Clark, Richard M.; Fahlgren, Noah; Fawcett, Jeffrey A.; Grimwood, Jane; Gundlach, Heidrun; Haberer, Georg; Hollister, Jesse D.; Ossowski, Stephan; Ottilar, Robert P.; Salamov, Asaf A.; Schneeberger, Korbinian; Spannagl, Manuel; Wang, Xi; Yang, Liang; Nasrallah, Mikhail E.; Bergelson, Joy; Carrington, James C.; Gaut, Brandon S.; Schmutz, Jeremy; Mayer, Klaus F. X.; Van de Peer, Yves; Grigoriev, Igor V.; Nordborg, Magnus; Weigel, Detlef; Guo, Ya-Long

2011-04-29T23:59:59.000Z

269

Data Management for High-Throughput Genomics  

E-Print Network (OSTI)

Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be automatically processed and made available to scientists for further analysis. This paper explores the potential and the limitations of using relational database systems as the data processing platform for high-throughput genomics. In particular, we are interested in the storage management for high-throughput sequence data and in leveraging SQL and user-defined functions for data analysis inside a database system. We give an overview of a database design for high-throughput genomics, how we used a SQL Server database in some unconventional ways to prototype this scenario, and we will discuss some initial findings about the scalability and performance of such a more database-centric approach.

Roehm, Uwe

2009-01-01T23:59:59.000Z

270

Artificial intelligence in genomic sequence, protein structure function prediction and DNA microarrays: a survey  

Science Conference Proceedings (OSTI)

Bioinformatics is conceptualising biology in terms of molecules (in the sense of physical chemistry) and applying 'informatics techniques' (derived from disciplines such as applied mathematics, computer science and statistics) ... Keywords: AI, ANNs, DNA microarrays, K-nearest neighbour, SVM, artificial intelligence, artificial neural networks, bioinformatics, data mining, decision trees, ensemble learning, genomic sequences, hidden Markov modelling, protein function prediction, protein structure, rough sets, support vector machine

Athanasios V. Vasilakos; Bing Niu; Liang Liu; Wencong Lu

2009-12-01T23:59:59.000Z

271

U.S. Department of Energy Joint Genome Institute Progress Report  

NLE Websites -- All DOE Office Websites (Extended Search)

U.S. Department of Energy Joint Genome Institute Progress Report Sequencing the world of possibilities for energy and the environment Table of Contents DOE JGI Mission ........................................................ 7 Director's Perspective.................................................... 8 DOE Mission Areas ................................................... 12 By the Numbers.......................................................... 14 User Map ............................................................ 15 Scientific Literature/Impact ................................ 16 DOE JGI Sequence Output .............................. 17 DOE JGI Team Science Realized ....................... 18 DOE JGI User Community ............................... 19 User Meeting 5 ...........................................................

272

Application of High Performance Computing to the DOE Joint Genomic...  

NLE Websites -- All DOE Office Websites (Extended Search)

Application of High Performance Computing to the DOE Joint Genomic Institute's Data Challenges January 25-26, 2010 DOE Joint Genome Institute, Walnut Creek, CA USA -by invitation...

273

JGI - Sequencing for the DOE Genomics: GTL Program  

NLE Websites -- All DOE Office Websites (Extended Search)

Educational Resources MyJGI: Information for Collaborators Sequencing for the DOE Genomics: GTL Program For status information, see the Genome Projects section. For more...

274

The Microbial Genomics and Metagenomics (MGM) five-day  

NLE Websites -- All DOE Office Websites (Extended Search)

Microbial Genomics and Metagenomics (MGM) five-day workshop (www.jgi.doe.gov meetingsmgm) provides strong and solid training in microbial genomic and metagenomic analysis and...

275

Rooted in Wonder: Joint Genome Institute Study Reveals Amazing...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Rooted in Wonder: Joint Genome Institute Study Reveals Amazing World Underfoot Rooted in Wonder: Joint Genome Institute Study Reveals Amazing World Underfoot August 13, 2012 -...

276

ComputationalComputational ScienceScience  

E-Print Network (OSTI)

ComputationalComputational ScienceScience KenKen HawickHawick k.a.k.a.hawickhawick@massey.ac.nz@massey.ac.nz Massey UniversityMassey University #12;Computational Science / eScienceComputational Science / eScience Computational Science concerns the application of computer science to physics, mathematics, chemistry, biology

Hawick, Ken

277

Genome resequencing in Populus: Revealing large-scale genome variation and implications on specialized-trait genomics  

Science Conference Proceedings (OSTI)

To date, Populus ranks among a few plant species with a complete genome sequence and other highly developed genomic resources. With the first genome sequence among all tree species, Populus has been adopted as a suitable model organism for genomic studies in trees. However, far from being just a model species, Populus is a key renewable economic resource that plays a significant role in providing raw materials for the biofuel and pulp and paper industries. Therefore, aside from leading frontiers of basic tree molecular biology and ecological research, Populus leads frontiers in addressing global economic challenges related to fuel and fiber production. The latter fact suggests that research aimed at improving quality and quantity of Populus as a raw material will likely drive the pursuit of more targeted and deeper research in order to unlock the economic potential tied in molecular biology processes that drive this tree species. Advances in genome sequence-driven technologies, such as resequencing individual genotypes, which in turn facilitates large scale SNP discovery and identification of large scale polymorphisms are key determinants of future success in these initiatives. In this treatise we discuss implications of genome sequence-enable technologies on Populus genomic and genetic studies of complex and specialized-traits.

Muchero, Wellington [ORNL; Labbe, Jessy L [ORNL; Priya, Ranjan [University of Tennessee, Knoxville (UTK); DiFazio, Steven P [West Virginia University, Morgantown; Tuskan, Gerald A [ORNL

2013-01-01T23:59:59.000Z

278

Plant Genomics Vol 3.pmd  

NLE Websites -- All DOE Office Websites (Extended Search)

Populus Populus Genome Initiative Stephen DiFazio Department of Biology, West Virginia University, Morgantown, West Virginia 26508-6057 USA Email: spdifazio@mail.wvu.edu 8 1 INTRODUCTION 1.1 Background on Populus Biology The genus Populus consists of about 29 species organized into six major sections that occur primarily in the Northern Hemisphere (Eckenwalder 1996). Species from the different sections of the genus have diverse ecological characteristics. Two of the most economically important sections (Aigeiros and Tacamahaca) contain species collectively known as cottonwoods. These occur mostly in riparian zones and are characterized by primarily ruderal life history, dominating early successional stages and thriving on flood-mediated disturbance (Braatne et al. 1996; Karrenberg et al. 2002). The other major section of the genus (section Populus,

279

Improved genome annotation for Zymomonas mobilis  

NLE Websites -- All DOE Office Websites (Extended Search)

USA. 3 Department of Genetics & Biotechnology, University of Athens, Athens, Greece. 4 Chemical Sciences Division and 5 Computer Science and Mathematics Division, Oak...

280

Investigating science teachers' beliefs about science and science teaching.  

E-Print Network (OSTI)

??The purposes of this quantitative, descriptive study were to investigate Saudi science teachers' beliefs about science and science teaching, and to determine how do Saudi (more)

AL-Abdulkareem, Saleh A. M., 1965-

2004-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

DOE Joint Genome Institute: Model Microbial Community for Studying  

NLE Websites -- All DOE Office Websites (Extended Search)

October 22, 2009 October 22, 2009 Model Microbial Community for Studying Expanding Dead Zones Characterized WALNUT CREEK, CA-Among the many changes in the ocean is the expansion of oxygen-deficient or oxygen minimum zones (OMZs), also known as dead zones, which affect the processes by which carbon is captured and sequestered on the seafloor and alter the microbial activities that impact the rate and magnitude of ocean carbon sequestration. Despite the importance of these effects, very little is known about the metabolism of OMZ microbes and how they respond to environmental changes. In the Oct. 23 issue of the journal Science, researchers from the University of British Columbia and the U.S. Department of Energy Joint Genome Institute (DOE JGI) describe the metagenome of an abundant but

282

Earth and Atmospheric Sciences | More Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Nuclear Forensics Climate & Environment Sensors and Measurements Chemical & Engineering Materials Computational Earth Science Systems Modeling Geographic Information Science and Technology Materials Science and Engineering Mathematics Physics More Science Home | Science & Discovery | More Science | Earth and Atmospheric Sciences SHARE Earth and Atmospheric Sciences At ORNL, we combine our capabilities in atmospheric science, computational science, and biological and environmental systems science to focus in the cross-disciplinary field of climate change science. We use computer models to improve climate change predications and to measure the impact of global warming on the cycling of chemicals in earth systems. Our Climate Change Science Institute uses models to explore connections among atmosphere,

283

ENVIRONMENTAL SCIENCE AND  

E-Print Network (OSTI)

ENVIRONMENTAL SCIENCE AND MANAGEMENT www.esr.pdx.edu Undergraduate Program: Environmental Science an emphasis on natural sciences and mathematics (Environmental Science) or emphasis on policy, geography and social sciences (Environmental Studies). Undergraduate Degrees Offered: Environmental Science Bachelor

284

Life Sciences Portal  

Science Conference Proceedings (OSTI)

NIST Home > Life Sciences Portal. Life Sciences Portal. Programs ... more. >> see all Life Sciences programs and projects ... ...

2012-12-18T23:59:59.000Z

285

Fusion Nuclear Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Nuclear Systems Modeling, Simulation & Validation Nuclear Systems Technology Reactor Technology Nuclear Science Home | Science & Discovery | Nuclear Science | Research...

286

Fusion Science at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

Rotating Plasma Finding is Key for ITER Heavy-Ion Fusion Science (HIFS) Math & Computer Science Nuclear Science Science Highlights HPC Requirements Reviews NERSC HPC Achievement...

287

NEWTON's Computer Science Videos  

NLE Websites -- All DOE Office Websites (Extended Search)

Computer Science Videos Do you have a great computer science video? Please click our Ideas page. Featured Videos: Computer Science Videos from Purdue Computer Science Videos from...

288

Science Accelerator : User Account  

NLE Websites -- All DOE Office Websites (Extended Search)

Energy Office of Science Office of Scientific and Technical Information Website PoliciesImportant Links Science Accelerator science.gov WorldWideScience.org Deep Web Technologies...

289

BER Science Network Requirements  

E-Print Network (OSTI)

Department of Energy, Office of Science, Office of Advancedthe Directors of the Office of Science, Office of AdvancedResearch, DOE Office of Science Energy Sciences Network

Dart, Eli

2011-01-01T23:59:59.000Z

290

ASCR Science Network Requirements  

E-Print Network (OSTI)

Computing Research, DOE Office of Science Energy SciencesDepartment of Energy, Office of Science, Office of Advancedthe Directors of the Office of Science, Office of Advanced

Dart, Eli

2010-01-01T23:59:59.000Z

291

A small trip in the untranquil world of genomes  

Science Conference Proceedings (OSTI)

Genomes are dynamic molecules that are constantly undergoing mutations and rearrangements. The latter are large scale changes in a genome organisation that participate in the evolutionary and speciation process, but may also be involved in inherited ... Keywords: Breakpoint region, Conserved segment, Genome dynamics, Rearrangement, Synteny block, Whole genome alignment

Claire Lemaitre; Marie-France Sagot

2008-05-01T23:59:59.000Z

292

Science Cinema  

NLE Websites -- All DOE Office Websites (Extended Search)

Cinema Science Experiments and Demonstrations Frostbite Theater - A collection of short, fun videos that you can use to explore liquid nitrogen, radioactivity, electricity and even...

293

Energy Science  

NLE Websites -- All DOE Office Websites (Extended Search)

sources of tomorrow-are the scientific tools of choice for exploring the electronic and atomic structure of matter. As such these photon-science facilities are uniquely...

294

Science Highlights  

NLE Websites -- All DOE Office Websites (Extended Search)

Introduction Science Highlights Operations Events Abstracts Publications Credits Cover images legend Disclaimer National Synchrotron Light Source Activity Report For the period...

295

Life Sciences Division Open Literature Publications  

E-Print Network (OSTI)

Human Subjects, Fall 2000 issue (2000) Human Genome Management Information Systems, Human Genome News 11

296

Prokaryotic Genomes from the Comprehensive Microbial Resource (CMR)  

DOE Data Explorer (OSTI)

The Comprehensive Microbial Resource (CMR) is a free website used to display information on all of the publicly available, complete prokaryotic genomes. In addition to the convenience of having all of the organisms on a single website, common data types across all genomes in the CMR make searches more meaningful, and cross genome analysis highlight differences and similarities between the genomes. For each genome not sequenced at TIGR two kinds of annotation are displayed: the Primary annotation taken from the genome sequencing center and the TIGR annotation generated by an automated annotation process at TIGR. Use the CMR to access information on all of the bacterial genomes or any subset of them.

297

Genome Engineering with TAL Effector Nucleases  

NLE Websites -- All DOE Office Websites (Extended Search)

Genome Engineering with TAL Effector Nucleases Print Genome Engineering with TAL Effector Nucleases Print Genome engineering (GE), an emerging discipline in which a DNA sequence is altered at a single position, has a wide variety of potential uses, such as the correction of gene sequences in patients suffering from genetic diseases, the modification or insertion of genes in plants, and the generation of unique cell lines for treatment of diseases such as cancer. GE requires the development of molecular tools that can search out and bind to one unique site within a complex genome while avoiding 'off-target' interactions across the remaining billions of DNA bases present in a cell's nucleus. Using ALS Beamline 5.0.2, researchers have solved the structure of one such tool called a TAL protein, learning its mechanism of action for DNA recognition and binding.

298

First international E. coli genome meeting  

SciTech Connect

This volume is a collection of abstracts of oral presentations and poster sessions of studies reported at the First International E. Coli Genome Meeting, held September 10-14, 1992 at the University of Wisconsin.

1992-01-01T23:59:59.000Z

299

First international E. coli genome meeting  

SciTech Connect

This volume is a collection of abstracts of oral presentations and poster sessions of studies reported at the First International E. Coli Genome Meeting, held September 10-14, 1992 at the University of Wisconsin.

1992-12-31T23:59:59.000Z

300

Genome Size Varaiation in D. melanogaster  

E-Print Network (OSTI)

As yet significant portions of the genetic variation in complex traits have not been explained with genome wide association experiments; and this has led to the search for the "missing heritability". Our data support the hypothesis that variation in genome size may account for some of the missing heritability. We measured female genome sizes for 34 Drosophila melanogaster inbred strains that derived from isofemale lines established from a natural population in Raleigh, NC, in addition to a group of 40 strains artificially selected for increased and decreased body size. We provide the first evidence that significant intraspecific genome size variation exists among these Drosophila melanogaster lines and that selection has a downsizing effect on the extent of variation.

Alfrejd, Benjamin

2011-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Rhodopseudomonas palustris genome project. Final report  

DOE Green Energy (OSTI)

Rhodopseudomonas palustris is a common soil and water bacterium that makes its living by converting sunlight to cellular energy and by absorbing atmospheric carbon dioxide and converting it to biomass. This microbe can also degrade and recycle components of the woody tissues of plants, wood being the most abundant polymer on earth. Because of its intimate involvement in carbon management and recycling, R. palustris was selected by the DOE Carbon Management Program to have its genome sequenced by the Joint Genome Institute (JGI). This award provided funds for the preparation of R. palustris genomic DNA which was then supplied to the JGI in sufficient amounts to enable the complete sequencing of the R. palustris genome. The PI also supplied the JGI with technical information about the molecular biology of R. palustris.

Harwood, Caroline S.

2000-11-22T23:59:59.000Z

302

Justice and the Human Genome Project  

Science Conference Proceedings (OSTI)

Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

Murphy, T.F.; Lappe, M. (eds.)

1992-01-01T23:59:59.000Z

303

Prokaryotic Genomes from Microbes Online Database  

DOE Data Explorer (OSTI)

To describe the potential functions of genes, MicrobesOnline includes protein family analyses (from InterPro and COG), metabolic maps (from KEGG), links to research papers (from UniProt and PubMed), and operon predictions for every genome. To examine each gene's evolutionary history, MicrobesOnline includes precomputed phylogenetic trees for all the gene families. It displays gene trees with genomic context or it compares the gene tree to the species tree. The tools provided with MicrobesOnline allow users to: compute customized motifs, sequence alignments, and phylogenetic trees change expression patterns in metabolic maps annotate genes in various ways The database contains more than 430 genomes. A browse tree tool and a genome browser are available, along with specialized search capabilities. (Specialized Interface)

Alm, Eric J.; Huang, Katherine H.; Price, Morgan N.; Koche, Richard P.; Keller, Keith; Dubchak, Inna L.; Arkin, Adam P.

304

DOE Joint Genome Institute 2008 Progress Report  

E-Print Network (OSTI)

Genomics of cellulosic biofuels. Nature, 454 (7206):841-845,2008 Termite Bellies and Biofuels (Published in Smithsonian,in the quest for viable biofuels. An estimated 10,000 marine

Gilbert, David

2009-01-01T23:59:59.000Z

305

Integrating genomic conservation data with motif discovery  

E-Print Network (OSTI)

We formalize a probabilistic model of inter-species sequence conservation for motif discovery, and demonstrate that adding large-scale genomic conservation data to an existing motif discovery procedure improves the quality ...

Danford, Timothy W. (Timothy William), 1979-

2004-01-01T23:59:59.000Z

306

Genome Engineering with TAL Effector Nucleases  

NLE Websites -- All DOE Office Websites (Extended Search)

Genome Engineering with TAL Effector Nucleases Print Genome Engineering with TAL Effector Nucleases Print Genome engineering (GE), an emerging discipline in which a DNA sequence is altered at a single position, has a wide variety of potential uses, such as the correction of gene sequences in patients suffering from genetic diseases, the modification or insertion of genes in plants, and the generation of unique cell lines for treatment of diseases such as cancer. GE requires the development of molecular tools that can search out and bind to one unique site within a complex genome while avoiding 'off-target' interactions across the remaining billions of DNA bases present in a cell's nucleus. Using ALS Beamline 5.0.2, researchers have solved the structure of one such tool called a TAL protein, learning its mechanism of action for DNA recognition and binding.

307

Genome Engineering with TAL Effector Nucleases  

NLE Websites -- All DOE Office Websites (Extended Search)

Genome Engineering with TAL Effector Nucleases Print Genome Engineering with TAL Effector Nucleases Print Genome engineering (GE), an emerging discipline in which a DNA sequence is altered at a single position, has a wide variety of potential uses, such as the correction of gene sequences in patients suffering from genetic diseases, the modification or insertion of genes in plants, and the generation of unique cell lines for treatment of diseases such as cancer. GE requires the development of molecular tools that can search out and bind to one unique site within a complex genome while avoiding 'off-target' interactions across the remaining billions of DNA bases present in a cell's nucleus. Using ALS Beamline 5.0.2, researchers have solved the structure of one such tool called a TAL protein, learning its mechanism of action for DNA recognition and binding.

308

Joint Genome Institute (JGI) Projects at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

Joint Genome Institute Joint Genome Institute (JGI) Joint Genome Institute (JGI) nicole-illumina-flowcell.jpg Key Challenges: Ensuring that there is a robust computational infrastructure for managing, storing and gleaning scientific insights from the torrent of data that constantly flows from the advanced sequencing platforms at the Department of Energy Joint Genome Institute (JGI). JGI sequencing capacity exceeds 40 billion DNA base pairs per year and is growing at a rate that exceeds computer hardware improvements, with exponential increases in computation and storage needed. JGI will generate about 1 petabyte of data in their first year as a NERSC partner; this is expected to double each year. Why it Matters: JGI is the primary production sequencing facility for the DOE. By revealing the genetic blueprint and fundamental principles that

309

Facilities and Equipment for Genomics/Comparative Functional Genomics at New York University  

Science Conference Proceedings (OSTI)

This award was for partial support for the renovation of space to house research laboratories and moveable scientific equipment for genomics/functional geonomics at New York University.

Lennie, Peter

2006-06-29T23:59:59.000Z

310

Genome Webcasts: Online Audio and Video Files about Genetics and the Human Genome Project  

DOE Data Explorer (OSTI)

\tPresentations from special events such as the White House Millenium Evening, Informatics Meets Genomics and from various scientific conferences

311

Funding Opportunities | U.S. DOE Office of Science (SC)  

NLE Websites -- All DOE Office Websites (Extended Search)

Opportunities Opportunities Funding Opportunities Grants & Contracts Support Award Search Find Funding Early Career Research Program Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 JGI Illumina Genome Sequencers BNL Joint Genome Institute genome sequencers. Lawrence Berkeley National Laboratory Print Text Size: A A A RSS Feeds FeedbackShare Page The Office of Science issues two types of funding announcements: Funding Opportunity Announcements (FOAs), which may be open to one or more institution types (please read the eligibility requirements in a given FOA for details); and DOE National Laboratory Announcements, which are open only to DOE Laboratories. FOAs and DOE National Laboratory Announcements may be issued either as

312

Frameshift detection in prokaryotic genomic sequences  

Science Conference Proceedings (OSTI)

We have developed a new method for frameshift detection, a combination of ab initio and alignment-based algorithms, that can serve as a useful tool for sequencing quality control in the next generation sequencing. We evaluated the method's accuracy ... Keywords: HMM, Markov chains, bioinformatics, frameshift, frameshift detection, genomics, hidden Markov model, machine learning, prokaryotic genomic sequences, protein coding, pyrosequencing, sensitivity, sequencing quality control, specificity

Andrey Kislyuk; Alexandre Lomsadze; Alla L. Lapidus; Mark Borodovsky

2009-07-01T23:59:59.000Z

313

Genomic sequencing of Pleistocene cave bears  

SciTech Connect

Despite the information content of genomic DNA, ancient DNA studies to date have largely been limited to amplification of mitochondrial DNA due to technical hurdles such as contamination and degradation of ancient DNAs. In this study, we describe two metagenomic libraries constructed using unamplified DNA extracted from the bones of two 40,000-year-old extinct cave bears. Analysis of {approx}1 Mb of sequence from each library showed that, despite significant microbial contamination, 5.8 percent and 1.1 percent of clones in the libraries contain cave bear inserts, yielding 26,861 bp of cave bear genome sequence. Alignment of this sequence to the dog genome, the closest sequenced genome to cave bear in terms of evolutionary distance, revealed roughly the expected ratio of cave bear exons, repeats and conserved noncoding sequences. Only 0.04 percent of all clones sequenced were derived from contamination with modern human DNA. Comparison of cave bear with orthologous sequences from several modern bear species revealed the evolutionary relationship of these lineages. Using the metagenomic approach described here, we have recovered substantial quantities of mammalian genomic sequence more than twice as old as any previously reported, establishing the feasibility of ancient DNA genomic sequencing programs.

Noonan, James P.; Hofreiter, Michael; Smith, Doug; Priest, JamesR.; Rohland, Nadin; Rabeder, Gernot; Krause, Johannes; Detter, J. Chris; Paabo, Svante; Rubin, Edward M.

2005-04-01T23:59:59.000Z

314

Titel Autor Jahr URL ABC Proteins I. Barry Holland/Susan Cole/Karl Kuchler/Christopher Higgins 2003 http://www.sciencedirect.com/science/book/9780123525512  

E-Print Network (OSTI)

/book/9780120845620 Biotechnology in the Pulp and Paper Industry L. Viikari, R. Lantto 2002 http://www.sciencedirect.com/science/publication?issn=09210423&volume=17 Foundations of Comparative Genomics Arcady R. Mushegian 2007 http://www.sciencedirect.com/science A R.S. Verma 1998 http://www.sciencedirect.com/science/issue/41823-1998-999949999.7998-649996 Genes

Osnabrück, University of

315

Nuclear Science at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

Accelerator Science Accelerator Science Astrophysics Biological Sciences Chemistry & Materials Science Climate & Earth Science Energy Science Engineering Science Environmental Science Fusion Science Math & Computer Science Nuclear Science Science Highlights NERSC Citations HPC Requirements Reviews Home » Science at NERSC » Nuclear Science Nuclear Science Experimental and theoretical nuclear research carried out at NERSC is driven by the quest for improving our understanding of the building blocks of matter. This includes discovering the origins of nuclei and identifying the forces that transform matter. Specific topics include: Nuclear astrophysics and the synthesis of nuclei in stars and elsewhere in the cosmos; Nuclear forces and quantum chromodynamics (QCD), the quantum field

316

Life sciences  

DOE Green Energy (OSTI)

This document is the 1989--1990 Annual Report for the Life Sciences Divisions of the University of California/Lawrence Berkeley Laboratory. Specific progress reports are included for the Cell and Molecular Biology Division, the Research Medicine and Radiation Biophysics Division (including the Advanced Light Source Life Sciences Center), and the Chemical Biodynamics Division. 450 refs., 46 figs. (MHB)

Day, L. (ed.)

1991-04-01T23:59:59.000Z

317

carleton.ca/science FACULTY OF SCIENCE  

E-Print Network (OSTI)

carleton.ca/science FACULTY OF SCIENCE ANYTHING BUT TEXTBOOK #12;Areas of study Bachelor of Computer Science* Algorithms Biomedical Computing Computer Game Development Computer and Internet Security Mathematics Computer Science and Mathematics Concentrations in Computing Theory and Numerical Methods

Carleton University

318

Bachelor of Science & Bachelor of Science (Technology)  

E-Print Network (OSTI)

Bachelor of Science & Bachelor of Science (Technology) SpecialiSationS Environmental Microbiology environment. This specialisation can be attached to the Environmental Sciences major. Environmental Modelling Sciences major. Land and Freshwater Environments This specialisation is for students interested

Waikato, University of

319

Integrated Microbial Genomes (IMG) System from the DOE Joint Genome Institute (JGI)  

DOE Data Explorer (OSTI)

The integrated microbial genomes (IMG) system is a data management, analysis and annotation platform for all publicly available genomes. IMG contains both draft and complete JGI microbial genomes integrated with all other publicly available genomes from all three domains of life, together with a large number of plasmids and viruses. IMG provides tools and viewers for analyzing and annotating genomes, genes and functions, individually or in a comparative context. Since its first release in 2005, IMG's data content and analytical capabilities have been constantly expanded through quarterly releases. IMG is provided by the DOE-Joint Genome Institute (JGI) and is available from http://img.jgi.doe.gov. [Abstract from The integrated microbial genomes (IMG) system in 2007: data content and analysis tool extensions; Victor M. Markowitz, Ernest Szeto, Krishna Palaniappan, Yuri Grechkin, Ken Chu, I-Min A. Chen, Inna Dubchak, Iain Anderson, Athanasios Lykidis, Konstantinos Mavromatis, Natalia N. Ivanova and Nikos C. Kyrpides; Nucleic Acids Research, 2008, Vol. 36. (Database Issue) See also the companion system, Integrated Microbial Genomes with Microbiome Samples.

320

Whole genome duplications, multi-break rearrangements, and genome halving problem  

Science Conference Proceedings (OSTI)

The Genome Halving Problem, motivated by the whole genome duplication events in molecular evolution, was solved by El-Mabrouk and Sankoff. The El-Mabrouk-Sankoff algorithm is rather complex inspiring a quest for a simpler solution. An alternative approach ...

Max A. Alekseyev; Pavel A. Pevzner

2007-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

"The Map of the Mexican's Genome": overlapping national identity, and population genomics  

Science Conference Proceedings (OSTI)

This paper explores the intersections between national identity and the production of medical/population genomics in Mexico. The ongoing efforts to construct a Haplotype Map of Mexican genetic diversity offers a unique opportunity to illustrate and analyze ... Keywords: Ethnography, Haplotypes, Mestizo identity, Nationalism, Population genomics

Ernesto Schwartz-Marn; Irma Silva-Zolezzi

2010-12-01T23:59:59.000Z

322

Structural characteristics of genomic islands associated with GMP synthases as integration hotspot among sequenced microbial genomes  

Science Conference Proceedings (OSTI)

tRNA, tmRNA and some small RNA genes are recognized as general integration hotspots of genomic islands (GIs). The GMP synthase gene (guaA) has been firstly identified as one insertion hotspot of foreign DNA fragments. Thirty four islands integrated into ... Keywords: AlpA, GMP synthase gene (guaA), Genomic island (GI), Integration hotspot, P4 integrase

Lei Song; Yuting Pan; Sihong Chen; Xuehong Zhang

2012-02-01T23:59:59.000Z

323

Security Science & Technology | Nuclear Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Security Treaty Verification Nuclear Systems Modeling, Simulation & Validation Nuclear Systems Technology Reactor Technology Nuclear Science Home | Science & Discovery |...

324

Materials Science Evaluation Portal  

Science Conference Proceedings (OSTI)

NIST Home > Materials Science Evaluation Portal. Materials Science Evaluation Portal. Subject Areas. Modeling; Nondestructive; ...

2013-08-08T23:59:59.000Z

325

Bioanalytical Science Group  

Science Conference Proceedings (OSTI)

Bioanalytical Science Group. Welcome. We provide the measurement science, standards, technology, and data required ...

2013-02-08T23:59:59.000Z

326

Argonne TDC: Physical Sciences  

Emergency Response. Engineering. Environmental Research. Fuel Cells. Imaging Technology. Material Science. Nanotechnology. Physical Sciences. Sensor ...

327

[Faculty of Science Information and Computing Sciences  

E-Print Network (OSTI)

Set Parser r = Input [r ? Input] #12;[Faculty of Science Information and Computing Sciences] 13) :: [ ] #12;[Faculty of Science Information and Computing Sciences] 13 Applicative interface fail : {r Parser r Parser r (p q) inp = p inp ++ q inp #12;[Faculty of Science Information and Computing Sciences

Löh, Andres

328

[Faculty of Science Information and Computing Sciences  

E-Print Network (OSTI)

of Science Information and Computing Sciences] 7 Regular functors Combinators for regular functors: data I r r #12;[Faculty of Science Information and Computing Sciences] 8 Converting between datatype[Faculty of Science Information and Computing Sciences] Generic programming with the multirec

Löh, Andres

329

Faculty of Science Computer Science Handbook  

E-Print Network (OSTI)

Faculty of Science Computer Science Handbook 2013 #12;Welcome to Computer Science Welcome from the Head of Department 2 What is Computer Science? 2 Careers in Computer Science 3 What can you do with a Computer Science degree? 4 Meet our students 5 Academic information Important dates 7 Admission

Sun, Jing

330

BES Science Network Requirements  

E-Print Network (OSTI)

the Directors of the Office of Science, Office of AdvancedBasic Energy Sciences, DOE Office of Science Energy SciencesDepartment of Energy, Office of Science, Office of Advanced

Dart, Eli

2011-01-01T23:59:59.000Z

331

COMPUTER SCIENCE EECS Department  

E-Print Network (OSTI)

COMPUTER SCIENCE EECS Department The Electrical Engineering and Computer Science (EECS) Department at WSU offers undergraduate degrees in electrical engineering, computer engineering and computer science. The EECS Department offers master of science degrees in computer science, electrical engineering

332

Computer Science UNDERGRADUATE  

E-Print Network (OSTI)

447 Computer Science UNDERGRADUATE PROGRAMS The Department of Computer Science provides undergraduate instruction leading to the bachelor's degree in computer science. This program in computer science is accredited by the Computer Science Accreditation Board (CSAB), a specialized accrediting body recognized

Suzuki, Masatsugu

333

Development of tools for the preparation of genomic libraries for next-generation sequencing  

E-Print Network (OSTI)

et al. (2008) Whole- genome sequencing and variant discoveryChen, Z. et al. (2005) Genome sequencing in microfabricatedS. (2008) Rapid genome sequencing with short universal

Joneja, Aric

2011-01-01T23:59:59.000Z

334

A korarchaeal genome reveals insights into the evolution of the Archaea  

E-Print Network (OSTI)

detailed protocol. Genome Sequencing and Assembly. LibrarySupport for genome sequencing and assembly was provided byCell Preparation and Genome Sequencing. It was observed that

Elkins, James G.

2008-01-01T23:59:59.000Z

335

Retrotransposition of gene transcripts leads to structural variation in mammalian genomes  

E-Print Network (OSTI)

for Broad Institute Genome Sequencing and Analysis Programsequenced by the Mouse Genome Sequencing Consortium [49] andto the Chimp Genome Sequencing Consortium 2.1/panTro2

2013-01-01T23:59:59.000Z

336

Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis  

E-Print Network (OSTI)

enabling non-optical genome sequencing. Nature 2011, 475:microarray analyses, genome sequencing, bioinformaticMDS-298 Genome recovery and sequencing (2746 forward)

2012-01-01T23:59:59.000Z

337

Complete genome sequence of Leptotrichia buccalis type strain (C-1013-bT)  

E-Print Network (OSTI)

with type strain genome sequencing projects registered inthe acknowledgements. Genome sequencing information Genomein Table 2. Table 2. Genome sequencing project information

Ivanova, Natalia

2010-01-01T23:59:59.000Z

338

Complete genome sequence of Coraliomargarita akajimensis type strain (04OKA010-24T)  

E-Print Network (OSTI)

with type strain genome sequencing projects registered inMavromatis et al. Genome sequencing and annotation Genomeparameters are - Genome sequencing and assembly consed -a

Mavromatis, Konstantinos

2010-01-01T23:59:59.000Z

339

Genome sequencing reveals fine scale diversification and reticulation history during speciation in Sus  

E-Print Network (OSTI)

as: Frantz et al. : Genome sequencing reveals fine scaleThornton K, Presgraves DC: Genome sequencing reveals complexRESEARCH Open Access Genome sequencing reveals fine scale

2013-01-01T23:59:59.000Z

340

Pigeonpea genomics initiative (PGI): an international effort to improve crop productivity of pigeonpea (Cajanus cajan L.)  

E-Print Network (OSTI)

and transcriptome/genome sequencing; Phase 3, plansfor large scale genome sequencing, and Phase 4, utilizingwould follow from genome sequencing, PGI has initiated the

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10T)  

E-Print Network (OSTI)

60%. Strains with a genome-sequencing project registered inacknowledgements. Genome sequencing and annotation Genomeet al. Table 2. Genome sequencing project information MIGS

Lapidus, Alla

2010-01-01T23:59:59.000Z

342

The positive role of the ecological community in the genomic revolution  

E-Print Network (OSTI)

Indeed, as the number of genome sequencing project increasesfrom major genome sequencing centres, researchers generatingNB, et al. (2006) Sequencing genomes from single cells by

Field, Dawn; Methe, Barbara; Nelson, Karen; Kyrpides, Nikos

2006-01-01T23:59:59.000Z

343

Computational methods for analyzing and detecting genomic structural variation : applications to cancer  

E-Print Network (OSTI)

Accurate whole human genome sequencing using reversibleson, S. , 2008: Rapid genome sequencing with short universalalterations in cancer. In Genome Sequencing Technology and

Bashir, Ali

2009-01-01T23:59:59.000Z

344

Complete genome sequence of Dyadobacter fermentans type strain (NS114T)  

E-Print Network (OSTI)

60%. Strains with a genome sequencing project registered inin the acknowledgements. Genome sequencing and annotationin Table 2. Table 2. Genome sequencing project information

Bristow, Jim

2010-01-01T23:59:59.000Z

345

Complete genome sequence of Catenulispora acidiphila type strain (ID 139908T)  

E-Print Network (OSTI)

60%. Strains with a genome sequencing project registered inin the acknowledgements. Genome sequencing and annotationin Table 2. Table 2. Genome sequencing project information

Copeland, Alex

2010-01-01T23:59:59.000Z

346

Combinatorial methods in computational genomics : mammalian phylogenetics using microinversions and fragment assembly with short reads  

E-Print Network (OSTI)

A diagram of whole genome sequencing strategies contrastingInternational Human Genome Sequencing Consortium. Initial921, 2008. [28] Mouse Genome Sequencing Consortium. Initial

Chaisson, Mark

2008-01-01T23:59:59.000Z

347

A Comparison of the First Two Sequenced Chloroplast Genomes in Asteraceae: Lettuce and Sunflower  

E-Print Network (OSTI)

used in the chloroplast genome sequencing. These differencesEST and nuclear genome sequencing efforts of the Compositaeand JLB performed the genome sequencing and draft assembly.

Timme, Ruth E.

2009-01-01T23:59:59.000Z

348

Whole genome sequencing of peach (Prunus persica L.) for SNP identification and selection  

E-Print Network (OSTI)

R, Abbott AG: Rosaceaous Genome Sequencing: Perspectives andal: Accurate whole human genome sequencing using reversibleas: Ahmad et al. : Whole genome sequencing of peach (Prunus

2011-01-01T23:59:59.000Z

349

Comparative genomics of metabolic capacities of regulons controlled by cis-regulatory RNA motifs in bacteria  

E-Print Network (OSTI)

RH, Breaker RR: Comparative genomics reveals 104 candidateof transporters. BMC Genomics 2008, 9:330. 16. Green NJ,in proteobacteria: comparative genomics analysis. FEMS

Sun, Eric I; Leyn, Semen A; Kazanov, Marat D; Saier, Milton H; Novichkov, Pavel S; Rodionov, Dmitry A

2013-01-01T23:59:59.000Z

350

Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets  

E-Print Network (OSTI)

components within functional genomics datasets BMC SystemssiRNA-based functional genomics of pigmentation identifiesrelated functional genomics data. J R Soc Interface Motulsky

Ho, Hsiang; Milenkovi?, Tijana; Memievi?, Vesna; Aruri, Jayavani; Prulj, Nataa; Ganesan, Anand K

2010-01-01T23:59:59.000Z

351

Genomics-based breeding in forest trees: are we there yet?  

E-Print Network (OSTI)

PRESENTATION Open Access Genomics-based breeding in forestEfforts to realize genomics-based breeding in conifer treeUSDA. The Conifer Translational Genomics Network Coordinated

Neale, David

2011-01-01T23:59:59.000Z

352

Evolutionary genomics of divergence and adaptation within the model fungi Neurospora crassa and Neurospora tetrasperma  

E-Print Network (OSTI)

Taylor JW. 2011. Population genomics and local adaptation inpromise of population genomics: from genotyping to genomeera. Annual Review of Genomics and Human Genetics 11:265-89.

Ellison, Christopher

2011-01-01T23:59:59.000Z

353

From Benefit Sharing to Power Sharing: Partnership Governance in Population Genomics Research  

E-Print Network (OSTI)

T. Greely, Iceland's Plan for Genomics Research: Facts andMike Fortun, Promising Genomics: Iceland and deCODE Geneticsabout commercialization in genomics research. 18 In this

Winickoff, David E

2008-01-01T23:59:59.000Z

354

MicrobesOnline: an integrated portal for comparative and functional genomics  

E-Print Network (OSTI)

for comparative and functional genomics Paramvir S. DehalUS Department of Energy Genomics: GTL program (grant DE-approach to comparative genomics, including a tree-based

Dehal, Paramvir

2013-01-01T23:59:59.000Z

355

RegPredict: an integrated system for regulon inference in prokaryotes by comparative genomics approach  

E-Print Network (OSTI)

motifs by comparative genomics. Nucleic Acids Res. , 28,M.S. (2009) Comparative genomics of regulation of fatty acidcomparative and functional genomics. Nucleic Acids Res. ,

Novichkov, Pavel S.

2010-01-01T23:59:59.000Z

356

Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters  

E-Print Network (OSTI)

Metabolic Complementarity and Genomics of the Dual BacterialMetabolic complementarity and genomics of the dual bacterialthe other. ) Comparative genomics. The predicted proteomes

2006-01-01T23:59:59.000Z

357

Comparative functional genomics of energy metabolism and insulin resistance in mammalian systems  

E-Print Network (OSTI)

oftwo-channelfunctionalgenomicsdata. (inreview). anddifferentiation. Genomics,2004. 84 (5):p. 876-ComparativeFunctionalGenomics ofEnergyMetabolismand

Hsiao, Albert

2005-01-01T23:59:59.000Z

358

Pigeonpea genomics initiative (PGI): an international effort to improve crop productivity of pigeonpea (Cajanus cajan L.)  

E-Print Network (OSTI)

009-9327-2 Pigeonpea genomics initiative (PGI): anIndia R. K. Varshney (&) Genomics Towards Gene Discoverycrop legume. To enable genomics-assisted breeding in this

2010-01-01T23:59:59.000Z

359

Update on the Pfam5000 Strategy for Selection of Structural Genomics Targets  

E-Print Network (OSTI)

Mizuguchi, "Structural genomics: an overview," Prog BiophysA tour of structural genomics," Nat Rev Genet, vol. 2, pp.Montelione, "Structural genomics: an approach to the protein

Chandonia, John-Marc; Brenner, Steven E.

2005-01-01T23:59:59.000Z

360

Discovering and validating biological hypotheses from coherent patterns in functional genomics data  

E-Print Network (OSTI)

patterns in functional genomics data Marcin P. Joachimiakpatterns in functional genomics data Marcin P. Joachimiakand Environmental Research, Genomics Program:GTL through

Joachimiak, Marcin Pawel

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Environmental genomics reveals a single species ecosystem deep within the Earth  

E-Print Network (OSTI)

Environmental genomics reveals a single species ecosystemMaterial for Environmental genomics reveals a single speciesTechnology Program, DOE Joint Genomics Institute, Berkeley,

Chivian, Dylan

2008-01-01T23:59:59.000Z

362

Combinatorial methods in computational genomics : mammalian phylogenetics using microinversions and fragment assembly with short reads  

E-Print Network (OSTI)

Methods in Computational Genomics: Mammalian Phylogeneticstheory of the method. Genomics, 4:114128, 1989. [37] JMethods in Computational Genomics: Mammalian Phylogenetics

Chaisson, Mark

2008-01-01T23:59:59.000Z

363

Population and conservation genomics of forest trees: seeing the forest for the trees  

E-Print Network (OSTI)

DB, Kremer A: Forest tree genomics: Growing resources andPopulation and conservation genomics of forest trees: seeingPopulation and conservation genomics of forest trees: seeing

Eckert, Andrew

2011-01-01T23:59:59.000Z

364

Applications of the Pipeline Environment for Visual Informatics and Genomics Computations  

E-Print Network (OSTI)

for visual informatics and genomics computations. BMCfor visual informatics and genomics computations Ivo D DinovContemporary informatics and genomics research require

2011-01-01T23:59:59.000Z

365

Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies  

E-Print Network (OSTI)

J Struct Funct Genomics (2009) 10:107125 DOIannotation for the structural genomics of the amidohydrolaseCenter for Structural Genomics (NYSGXRC) that aims to

2009-01-01T23:59:59.000Z

366

Comparative chloroplast genomics: Analyses including new sequences from the angiosperms Nuphar advena and Ranunculus macranthus  

E-Print Network (OSTI)

to other angiosperms. BMC Genomics 2006, 7:61. 20.history of chloroplast genomics. Photosynth Res 2003, 76:Comparative chloroplast genomics: Analyses including new

2007-01-01T23:59:59.000Z

367

Logic, genomics, and evolution of the peripheral nervous system transcriptional network of Drosophila  

E-Print Network (OSTI)

CALIFORNIA, SAN DIEGO Logic, genomics, and evolution of thetechnician in a cattle genomics lab, I decided to apply toBiology Studies in Developmental Genomics Professor James W.

Rebeiz, Mark John

2006-01-01T23:59:59.000Z

368

To Know Ourselves: The U.S. Department of Energy and The Human Genome Project  

DOE R&D Accomplishments (OSTI)

The Genome Project and its various aspects: why the DOE?; introducing the human genome; exploring the genomic landscape; beyond biology; and ethical, legal, and social implications.

1996-07-00T23:59:59.000Z

369

Sorghum genome sequencing by methylation filtration  

E-Print Network (OSTI)

Sorghum bicolor is a close relative of maize and is a staple crop in Africa and much of the developing world because of its superior tolerance of arid growth conditions. We have generated sequence from the hypomethylated portion of the sorghum genome by applying methylation filtration (MF) technology. The evidence suggests that 96 % of the genes have been sequence tagged, with an average coverage of 65 % across their length. Remarkably, this level of gene discovery was accomplished after generating a raw coverage of less than 300 megabases of the 735-megabase genome. MF preferentially captures exons and introns, promoters, microRNAs, and simple sequence repeats, and minimizes interspersed repeats, thus providing a robust view of the functional parts of the genome. The sorghum MF sequence set is beneficial to research on sorghum and is also a powerful resource for comparative genomics among the grasses and across the entire plant kingdom. Thousands of hypothetical gene predictions in rice and Arabidopsis are supported by the sorghum dataset, and genomic similarities highlight evolutionarily conserved regions that will lead to a better understanding of rice and Arabidopsis.

Joseph A. Bedell; Muhammad A. Budiman; Andrew Nunberg; Robert W. Citek; Dan Robbins; Joshua Jones; Elizabeth Flick; Theresa Rohlfing; Jason Fries; Kourtney Bradford; Jennifer Mcmenamy; Michael Smith; Heather Holeman; Bruce A. Roe; Graham Wiley; Ian F. Korf; Pablo D. Rabinowicz; Nathan Lakey; W. Richard Mccombie; Jeffrey A. Jeddeloh; Robert A. Martienssen

2005-01-01T23:59:59.000Z

370

Energy Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Energy Science Energy Science Energy Science Print Our current fossil-fuel-based system is causing potentially catastrophic changes to our planet. The quest for renewable, nonpolluting sources of energy requires us to understand, predict, and ultimately control matter and energy at the electronic, atomic, and molecular levels. Light-source facilities-the synchrotrons of today and the next-generation light sources of tomorrow-are the scientific tools of choice for exploring the electronic and atomic structure of matter. As such these photon-science facilities are uniquely positioned to jump-start a global revolution in renewable and carbon-neutral energy technologies. To establish the scientific foundations for the kind of transformative breakthroughs needed to build a 21st-century energy economy, we must address fundamental questions involving matter and energy. Below is a sampling of such questions that can be addressed by light-source facilities:

371

Science Museum  

NLE Websites -- All DOE Office Websites (Extended Search)

- 1 - Nanotechnology and algae biofuels exhibits open July 26 at the Bradbury Science Museum July 22, 2013 LOS ALAMOS, N.M., July 22, 2013-Los Alamos National Laboratory's Bradbury...

372

ARM - Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Read about the 20 years of accomplishments (PDF, 696KB) from the ARM Program and user facility. Performance Metrics ASR Metrics 2009 2008 2007 2006 Science New C-band...

373

Applied Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Nuclear Science EXAFS and XANES of plutonium and uranium edges from titanate ceramics for fissile materials disposition J.A. Fortner, A.J. Kropf, R.J. Finch, M.C. Hash, S.B. Aase,...

374

Science Museum  

NLE Websites -- All DOE Office Websites (Extended Search)

lecture December 12, 2013 Last in year-long series of public talks at Bradbury Science Museum LOS ALAMOS, N.M., Dec. 12, 2013-The role Los Alamos National Laboratory plays...

375

Nuclear Science  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Science Science and Engineering Education Sourcebook 2013 American Nuclear Society US Department of Energy Nuclear Science & Engineering Education Sourcebook 2013 North American Edition American Nuclear Society Education, Training, and Workforce Division US Department of Energy Office of Nuclear Energy Editor and Founder John Gilligan Professor of Nuclear Engineering North Carolina State University Version 5.13 Welcome to the 2013 Edition of the Nuclear Science and Engineering Education (NS&EE) Sourcebook. We have evolved and improved! The core mission of the Sourcebook has not changed, however. Our purpose is to facilitate interaction among faculty, students, industry, and government agencies to accomplish nuclear research, teaching and service activities. Since 1986 we have compiled critical information on nuclear

376

DOE Joint Genome Institute: Genes from Tiny Algae Shed Light on Big Role  

NLE Websites -- All DOE Office Websites (Extended Search)

April 9, 2009 April 9, 2009 Genes from Tiny Algae Shed Light on Big Role Managing Carbon in World's Oceans & Coping with Environmental Change WALNUT CREEK, CA-Scientists from two-dozen research organizations led by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) and the Monterey Bay Aquarium Research Institute (MBARI) have decoded genomes of two algal strains, highlighting the genes enabling them to capture carbon and maintain its delicate balance in the oceans. These findings, from a team led by Alexandra Z. Worden of MBARI and published in the April 10 edition of the journal Science, will illuminate cellular processes related to algae-derived biofuels being pursued by DOE scientists. The study sampled two geographically diverse isolates of the photosynthetic

377

The Los Alamos Science Pillars The Science of Signatures  

Science Conference Proceedings (OSTI)

As a national security science laboratory, Los Alamos is often asked to detect and measure the characteristics of complex systems and to use the resulting information to quantify the system's behavior. The Science of Signatures (SoS) pillar is the broad suite of technical expertise and capability that we use to accomplish this task. With it, we discover new signatures, develop new methods for detecting or measuring signatures, and deploy new detection technologies. The breadth of work at Los Alamos National Laboratory (LANL) in SoS is impressive and spans from the initial understanding of nuclear weapon performance during the Manhattan Project, to unraveling the human genome, to deploying laser spectroscopy instrumentation on Mars. Clearly, SoS is a primary science area for the Laboratory and we foresee that as it matures, new regimes of signatures will be discovered and new ways of extracting information from existing data streams will be developed. These advances will in turn drive the development of sensing instrumentation and sensor deployment. The Science of Signatures is one of three science pillars championed by the Laboratory and vital to supporting our status as a leading national security science laboratory. As with the other two pillars, Materials for the Future and Information Science and Technology for Predictive Science (IS&T), SoS relies on the integration of technical disciplines and the multidisciplinary science and engineering that is our hallmark to tackle the most difficult national security challenges. Over nine months in 2011 and 2012, a team of science leaders from across the Laboratory has worked to develop a SoS strategy that positions us for the future. The crafting of this strategy has been championed by the Chemistry, Life, and Earth Sciences Directorate, but as you will see from this document, SoS is truly an Institution-wide effort and it has engagement from every organization at the Laboratory. This process tapped the insight and imagination of many LANL staff and managers and resulted in a strategy which focuses on our strengths while recognizing that the science of signatures is dynamic. This report highlights the interdependence between SoS, advances in materials science, and advances in information technology. The intent is that SoS shape and inform Los Alamos investments in nuclear forensics, nuclear diagnostics, climate, space, energy, and biosurveillence; the areas of leadership that you will read about in this strategy document. The Science of Signatures is still a relatively new strategic direction for the Laboratory. The primary purpose of this document is tell Laboratory staff how SoS is being managed and give them a chance to get involved. A second important purpose is to inform the Department of Energy and our customers of our capability growth in this important scientific area. Questions concerning the SoS strategy and input to it are welcomed and may be directed to any member of the SoS Leadership Council or to the Chemistry, Life, and Earth Science Directorate Office.

Smith, Joshua E. [Los Alamos National Laboratory; Peterson, Eugene J. [Los Alamos National Laboratory

2012-09-13T23:59:59.000Z

378

Standards for a new genomic era  

NLE Websites -- All DOE Office Websites (Extended Search)

Standards for new genomic era Standards for new genomic era Standards for a new genomic era A team of geneticists has recently proposed a set of standards designed to elucidate the quality of publicly available genetic sequencing information. October 21, 2009 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials. Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials. Contact

379

Genome-Facilitated Analyses of Geomicrobial Processes  

SciTech Connect

This project had the goal(s) of understanding the mechanism(s) of extracellular electron transport (EET) in the microbe Shewanella oneidensis MR-1, and a number of other strains and species in the genus Shewanella. The major accomplishments included sequencing, annotation, and analysis of more than 20 Shewanella genomes. The comparative genomics enabled the beginning of a systems biology approach to this genus. Another major contribution involved the study of gene regulation, primarily in the model organism, MR-1. As part of this work, we took advantage of special facilities at the DOE: e.g., the synchrotron radiation facility at ANL, where we successfully used this system for elemental characterization of single cells in different metabolic states (1). We began work with purified enzymes, and identification of partially purified enzymes, leading to initial characterization of several of the 42 c-type cytochromes from MR-1 (2). As the genome became annotated, we began experiments on transcriptome analysis under different conditions of growth, the first step towards systems biology (3,4). Conductive appendages of Shewanella, called bacterial nanowires were identified and characterized during this work (5, 11, 20,21). For the first time, it was possible to measure the electron transfer rate between single cells and a solid substrate (20), a rate that has been confirmed by several other laboratories. We also showed that MR-1 cells preferentially attach to cells at a given charge, and are not attracted, or even repelled by other charges. The interaction with the charged surfaces begins with a stimulation of motility (called electrokinesis), and eventually leads to attachment and growth. One of the things that genomics allows is the comparative analysis of the various Shewanella strains, which led to several important insights. First, while the genomes predicted that none of the strains looked like they should be able to degrade N-acetyl glucosamine (NAG), the monomer that makes up chitin, virtually all of the strains were in fact capable. This led to the discovery of a great many new genes involved with chitin and NAG metabolism (7). In a similar vein, a detailed study of the sugar utilization pathway revealed a major new insight into the regulation of sugar metabolism in this genus (19). Systems Biology and Comparative Genomics of the shewanellae: Several publications were put together describing the use of comparative genomics for analyses of the group Shewanella, and these were a logical culmination of our genomic-driven research (10,15,18). Eight graduate students received their Ph.D. degrees doing part of the work described here, and four postdoctoral fellows were supported. In addition, approximately 20 undergraduates took part in projects during the grant period.

Kenneth H. Nealson

2012-05-02T23:59:59.000Z

380

Genomic Data and Annotation from the SEED  

DOE Data Explorer (OSTI)

The SEED Project has been extended to support metagenomic samples and concomitant analytical tools. Moreover, the number of genomes being introduced into SEED is growing very rapidly. Building a framework to support this growth while providing highly accurate annotations is centrally important to SEED. The projects subsystem-based annotation strategy has become the technological foundation for addressing these challenges.(copied from Appendix 7 of Systems Biology Knowledgebase for a New Era in Biology, A Genomics:GTL Report from the May 2008 Workshop, DOE/SC-0113, Grequrick, S; Fredrickson, J.K.; Stevens, R., Pub March 1, 2009.)

Fonstein, Michael; Kogan, Yakov; Osterman, Andrei; Overbeek, Ross; Vonstein, Veronika The Fellowship for Interpretation of Genomes (FIG)

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Neutron Science | More Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

of the 1994 Nobel Prize in Physics for this groundbreaking work. Today, the laboratory is home to two of the most powerful neutron science facilities in the world-the Spallation...

382

Initial impact of the sequencing of the human genome  

E-Print Network (OSTI)

The sequence of the human genome has dramatically accelerated biomedical research. Here I explore its impact, in the decade since its publication, on our understanding of the biological functions encoded in the genome, on ...

Massachusetts Institute of Technology. Dept. of Biology; Broad Institute of MIT and Harvard; Lander, Eric S.; Lander, Eric S.

383

Error and Error Mitigation in Low-Coverage Genome Assemblies  

E-Print Network (OSTI)

The recent release of twenty-two new genome sequences has dramatically increased the data available for mammalian comparative genomics, but twenty of these new sequences are currently limited to ~2 coverage. Here we examine ...

Hubisz, Melissa J.

384

Efficiently identifying significant associations in genome-wide association studies  

Science Conference Proceedings (OSTI)

Over the past several years, genome wide association studies (GWAS) have implicated hundreds of genes in common disease. More recently, the GWAS approach has been utilized to identify regions of the genome which harbor variation affecting gene expression ...

Emrah Kostem; Eleazar Eskin

2013-04-01T23:59:59.000Z

385

Novel phylogenetic approaches to problems in microbial genomics  

E-Print Network (OSTI)

Present day microbial genomes are the handiwork of over 3 billion years of evolution. Comparisons between these genomes enable stepping backwards through past evolutionary events, and can be formalized using binary tree ...

David, Lawrence A. (Lawrence Anthony)

2010-01-01T23:59:59.000Z

386

The human genome initiative of the Department of Energy  

DOE Green Energy (OSTI)

The structural characterization of genes and elucidation of their encoded functions have become a cornerstone of modern health research, biology and biotechnology. A genome program is an organized effort to locate and identify the functions of all the genes of an organism. Beginning with the DOE-sponsored, 1986 human genome workshop at Santa Fe, the value of broadly organized efforts supporting total genome characterization became a subject of intensive study. There is now national recognition that benefits will rapidly accrue from an effective scientific infrastructure for total genome research. In the US genome research is now receiving dedicated funds. Several other nations are implementing genome programs. Supportive infrastructure is being improved through both national and international cooperation. The Human Genome Initiative of the Department of Energy (DOE) is a focused program of Resource and Technology Development, with objectives of speeding and bringing economies to the national human genome effort. This report relates the origins and progress of the Initiative. 34 refs.

none,

1988-01-01T23:59:59.000Z

387

DOE Joint Genome Institute: Opening New Frontiers: First Volume...  

NLE Websites -- All DOE Office Websites (Extended Search)

in the spirit of his goal of providing "light to the obscure," the Department of Energy Joint Genome Institute (DOE JGI) has published the initial "volume" of the Genomic...

388

JGI Genomics and Bioinformatics for Undergraduate Educators Workshop |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

JGI Genomics and Bioinformatics for Undergraduate Educators JGI Genomics and Bioinformatics for Undergraduate Educators Workshop JGI Genomics and Bioinformatics for Undergraduate Educators Workshop March 23, 2013 3:00PM EDT to March 26, 2013 6:00PM EDT University of California The JGI will be holding the JGI Genomics and Bioinformatics for Undergraduate Educators Workshop in conjunction with the JGI User Meeting. The workshop will take place March 23-26, 2013 at the JGI. The DOE Joint Genome Institute's Education Program is providing opportunities for colleges and universities across the country to "interpret" bacterial genomes, such as those sequenced as part of the GEBA project, for analysis. This "Interpret a GEBA Genome" Education Program makes available a selection of recently sequenced genomes

389

Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species  

E-Print Network (OSTI)

in de novo plant genome sequencing and assembly. Genome BiolJ: Haplotype-resolved genome sequencing of a Gujarati Indianambitious multi-species genome sequencing projects such as

2013-01-01T23:59:59.000Z

390

MicrobesOnline: an integrated portal for comparative and functional genomics  

E-Print Network (OSTI)

the US Department of Energy Genomics: GTL program (DE-AC02-Web site for comparative genomics. Genome Res, 15, 1015-comparative and functional genomics Paramvir S. Dehal 1,2* ,

Dehal, Paramvir S.

2010-01-01T23:59:59.000Z

391

Materials Science & Engineering | More Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Advanced Materials Clean Energy Materials Theory and Simulation Neutron Science Nuclear Forensics Nuclear Science Supercomputing Theory, Modeling and Simulation Mathematics Physics More Science Home | Science & Discovery | More Science | Materials Science and Engineering SHARE Materials Science and Engineering ORNL's core capability in applied materials science and engineering directly supports missions in clean energy, national security, and industrial competitiveness. A key strength of ORNL's materials science program is the close coupling of basic and applied R&D. Programs building on this core capability are focused on (1) innovations and improvements in materials synthesis, processing, and design; (2) determination and manipulation of critical structure-property relationships, and (3)

392

Contact ORNL Neutron Sciences  

NLE Websites -- All DOE Office Websites (Extended Search)

Sciences Organization Charts Neutron Sciences Directorate Associate Laboratory Director for Neutron Sciences, Kelly Beierschmitt Biology and Soft Matter Division Director, Paul...

393

More Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology Chemistry Engineering Computer Science Earth and Atmospheric Sciences Materials Science and Engineering Mathematics Physics ORNL wins six R&D 100s R&D Magazine recognizes...

394

NERSC Science Gateways  

NLE Websites -- All DOE Office Websites (Extended Search)

Analytics & Visualization Science Gateways Demos Database services OpenDAP User Surveys NERSC Users Group User Announcements Help Home For Users Science Gateways Science...

395

ASCR Science Network Requirements  

E-Print Network (OSTI)

ASCR Science Network Requirements Office of AdvancedScientific Computing Research, DOE Office of ScienceEnergy Sciences Network Gaithersburg, MD April 15 and 16,

Dart, Eli

2010-01-01T23:59:59.000Z

396

BER Science Network Requirements  

E-Print Network (OSTI)

of Energy, Office of Science, Office of Advanced Scientificthe Directors of the Office of Science, Office of Advanced5 Simulation Data Key Remote Science Drivers Instruments and

Dart, Eli

2011-01-01T23:59:59.000Z

397

History of Science 157 Sociology of Science  

E-Print Network (OSTI)

1 History of Science 157 Sociology of Science Fall 2009 Steven Shapin Science Center 469 Tuesdays to thinking about science, its historical development, its relations to society and other forms of culture: Science Center 451 Office hours: Mondays 8:30 -> 10.15, or by arrangement #12;2 E-mail: shapin

Shapin, Steven

398

www.ucd.ie/science UCD SCIENCE  

E-Print Network (OSTI)

* D N 200 SC IEN C E 4 N ew Pathw ays to Teaching M athem atics and Science www.ucd.ie/science UCD SCIENCE 2013 Discover. Experience. Choose. #12;2 www.ucd.ie/science Biochemistry & Molecular Biology 6 DN & Biomolecular Sciences Pharmacology 12 DN200 Neuroscience 11 DN200 Plant Biology 14 DN200 Physiology 13 DN200

399

Third International E. coli genome meeting  

SciTech Connect

Proceedings of the Third E. Coli Genome Meeting are provided. Presentations were divided into sessions entitled (1) Large Scale Sequencing, Sequence Analysis; (2) Databases; (3) Sequence Analysis; (4) Sequence Divergence in E. coli Strains; (5) Repeated Sequences and Regulatory Motifs; (6) Mutations, Rearrangements and Stress Responses; and (7) Origins of New Genes. The document provides a collection of abstracts of oral and poster presentations.

1994-12-31T23:59:59.000Z

400

Taking stock of the genome project  

SciTech Connect

This article describes the various projects within the Human Genome Project, and what their progress has been in terms of goals met and money spent. The discussion focuses on the need for more funding, and what projects should receive increased funding and which ones should not. The article also describes some of the shifts in research emphasis under a new director.

Roberts, L.

1993-10-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Comparative Analysis of Genome Sequences with VISTA  

DOE Data Explorer (OSTI)

VISTA is a comprehensive suite of programs and databases developed by and hosted at the Genomics Division of Lawrence Berkeley National Laboratory. They provide information and tools designed to facilitate comparative analysis of genomic sequences. Users have two ways to interact with the suite of applications at the VISTA portal. They can submit their own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species. A key menu option is the Enhancer Browser and Database at http://enhancer.lbl.gov/. The VISTA Enhancer Browser is a central resource for experimentally validated human noncoding fragments with gene enhancer activity as assessed in transgenic mice. Most of these noncoding elements were selected for testing based on their extreme conservation with other vertebrates. The results of this enhancer screen are provided through this publicly available website. The browser also features relevant results by external contributors and a large collection of additional genome-wide conserved noncoding elements which are candidate enhancer sequences. The LBL developers invite external groups to submit computational predictions of developmental enhancers. As of 10/19/2009 the database contains information on 1109 in vivo tested elements - 508 elements with enhancer activity.

Dubchak, Inna

402

Systems analysis of genomes: Towards a "topobiology"  

E-Print Network (OSTI)

the E. coli genome (mmol/g-DCW/hr). The average proteinribosomes, mass = 4.33 10 ?13 g-DCW/cell, and density= 382.72 g-DCW/L [31]. Demands Random All Data CV s (%) AAs

Allen, Timothy Eric

2006-01-01T23:59:59.000Z

403

Genome Technology Program Bibliography Publications and Patents  

E-Print Network (OSTI)

NHGRI launched an ambitious program in 2004 to reduce the cost of full genome sequencing initially by 100-fold and subsequently by an additional 100-fold. Below, listed by Principal Investigator, are citations and links to many of the articles and patents resulting from this and closely related programs.

Benner Steven A

2010-01-01T23:59:59.000Z

404

New computational tools for Brassica genome research: Conference Reviews  

Science Conference Proceedings (OSTI)

With the increasing quantities of Brassica genomic data being entered into the public domain and in preparation for the complete Brassica genome sequencing effort, there is a growing requirement for the structuring and detailed bioinformatic ... Keywords: ASTRA, EnsEMBL, Gene Ontology (GO), bacterial artificial chromosome (BAC), genome sequencing, molecular marker

Christopher G. Love; Jacqueline Batley; Geraldine Lim; Andrew J. Robinson; David Savage; Daniel Singh; German C. Spangenberg; David Edwards

2004-04-01T23:59:59.000Z

405

A linguistic approach to classification of bacterial genomes  

Science Conference Proceedings (OSTI)

In the present paper, 188 prokaryote genomes are classified by separately calculating the compositional spectra for the coding and the non-coding parts of the genomes. For each subsequence, the compositional spectrum is transformed into the corresponding ... Keywords: Cluster validation, Compositional spectra method, Genome clustering

Zeev Volkovich; Valery Kirzhner; Zeev Barzily; Sergey Hosid; Katerina Korenblat

2010-03-01T23:59:59.000Z

406

Methodological Review: 'Big data', Hadoop and cloud computing in genomics  

Science Conference Proceedings (OSTI)

Since the completion of the Human Genome project at the turn of the Century, there has been an unprecedented proliferation of genomic sequence data. A consequence of this is that the medical discoveries of the future will largely depend on our ability ... Keywords: Big data, Bioinformatics, Cloud computing, Genomics, Hadoop

Aisling O' Driscoll, Jurate Daugelaite, Roy D. Sleator

2013-10-01T23:59:59.000Z

407

The US Department of Energy Joint Genome Institute Microbial Genome Program  

E-Print Network (OSTI)

Community Sequencing Program (CSP). 24 proposals accepted 10http://www.jgi.doe.gov/CSP/ US DOE Joint Genome InstituteGTL) Community Sequencing Program (CSP) JGI Internal Program

Lapidus, Alla

2005-01-01T23:59:59.000Z

408

Genomics of Climate Resilience (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)  

SciTech Connect

Eldredge Bermingham of the Smithsonian Tropical Research Institute-Panama on "Genomics of climate resilience" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

Bermingham, Eldredge [STRI-Panama

2013-03-27T23:59:59.000Z

409

The Sunflower Genome and its Evolution (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

Science Conference Proceedings (OSTI)

Loren Rieseberg from the University of British Columbia on "The Sunflower Genome and its Evolution" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

Rieseberg, Loren [University of British Columbia

2012-03-21T23:59:59.000Z

410

Entering the Era of Mega-genomics ( JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)  

Science Conference Proceedings (OSTI)

Michael Schatz from Cold Spring Harbor Laboratory on "Entering the Era of Mega-genomics" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif.

Schatz, Michael C [Cold Spring Harbor Laboratory

2012-03-21T23:59:59.000Z

411

Using Genomics to Dissect Seed Development (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment Meeting)  

Science Conference Proceedings (OSTI)

Robert Goldberg of UCLA presents "Using Genomics to Dissect Seed Development" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

Goldberg, Robert [UCLA

2012-03-21T23:59:59.000Z

412

A rapid whole genome sequencing and analysis system supporting genomic epidemiology (7th Annual SFAF Meeting, 2012)  

Science Conference Proceedings (OSTI)

Michael FitzGerald on "A rapid whole genome sequencing and analysis system supporting genomic epidemiology" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

FitzGerald, Michael [Broad Institute

2012-06-01T23:59:59.000Z

413

SCIENCE Program  

NLE Websites -- All DOE Office Websites (Extended Search)

SCIENCE Program SCIENCE Program early science program Early at the Argonne Leadership Computing Facility CONTACT  Argonne Leadership Computing Facility | www.alcf.anl.gov | (877) 737-8615 Climate-Weather Modeling Studies Using a Prototype Global Cloud-System Resolving Model PI: Venkatramani Balaji Geophysical Fluid Dynamics Laboratory Award: 150 Million Hours Materials Design and Discovery: Catalysis and Energy Storage PI: Larry Curtiss Argonne National Laboratory Award: 50 Million Hours Direct Numerical Simulation of Autoignition in a Jet in a Cross-Flow PI: Christos Frouzakis Swiss Federal Institute of Technology Award: 150 Million Hours High-Accuracy Predictions of the Bulk Properties of Water PI: Mark Gordon Iowa State University Award: 150 Million Hours Cosmic Structure Probes

414

EMSL: Science: Cross-Cutting Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Cross-Cutting Science Areas Cross-cutting science EMSL's integrated approach supports science that doesn't fit easily into single categories. Here we capture EMSL's areas of...

415

Yeast Ancestral Genome Reconstructions - CECM - Simon Fraser ...  

E-Print Network (OSTI)

2Faculty of Natural Sciences, University of Sarajevo, Sarajevo, Bosnia and Herzegovina. 3INRIA Lille-Nord-Europe, Universit? Lille 1, LIFL, UMR CNRS 8022,...

416

Scrambled Science Words  

NLE Websites -- All DOE Office Websites (Extended Search)

Scrambled Science Words Welcome to Scrambled Science Words Welcome to Scrambled Science Words The computer will pick a science word or term and then scramble its letters. Once you...

417

Science in the News  

Office of Scientific and Technical Information (OSTI)

Science in the News Now you can get science news from many U.S. science agencies via a new feed at Science.gov. From aftershock assessment of earthquakes to food recalls to U.S....

418

Anthropology Bachelor of Science  

E-Print Network (OSTI)

Anthropology Bachelor of Science 201213 Degree Map First Year Fall Winter Spring Notes ANTH 1031 4 Lab Science Elective 4 Lab Science Elective 4 Science Elective 4 Total Credits

Bertini, Robert L.

419

Understanding Materials Science History, Science, Applications - TMS  

Science Conference Proceedings (OSTI)

Feb 10, 2007 ... CITATION: Hummel, R.E. Understanding Materials Science History, Science, Applications, 2nd Edition, New York: Springer, 2004.

420

Jefferson Lab Science Series - Adventures in Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Physics IQ Test Previous Video (Physics IQ Test) Science Series Video Archive Next Video (Polymers, Foams and Gels) Polymers, Foams and Gels Adventures in Science Professor Cynthia...

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Algorithms for Gene Clustering Analysis on Genomes  

E-Print Network (OSTI)

The increased availability of data in biological databases provides many opportunities for understanding biological processes through these data. As recent attention has shifted from sequence analysis to higher-level analysis of genes across multiple genomes, there is a need to develop efficient algorithms for these large-scale applications that can help us understand the functions of genes. The overall objective of my research was to develop improved methods which can automatically assign groups of functionally related genes in large-scale data sets by applying new gene clustering algorithms. Proposed gene clustering algorithms that can help us understand gene function and genome evolution include new algorithms for protein family classification, a window-based strategy for gene clustering on chromosomes, and an exhaustive strategy that allows all clusters of small size to be enumerated. I investigate the problems of gene clustering in multiple genomes, and define gene clustering problems using mathematical methodology and solve the problems by developing efficient and effective algorithms. For protein family classification, I developed two supervised classification algorithms that can assign proteins to existing protein families in public databases and, by taking into account similarities between the unclassified proteins, allows for progressive construction of new families from proteins that cannot be assigned. This approach is useful for rapid assignment of protein sequences from genome sequencing projects to protein families. A comparative analysis of the method to other previously developed methods shows that the algorithm has a higher accuracy rate and lower mis-classification rate when compared to algorithms that are based on the use of multiple sequence alignments and hidden Markov models. The proposed algorithm performs well even on families with very few proteins and on families with low sequence similarity. Apart from the analysis of individual sequences, identifying genomic regions that descended from a common ancestor helps us study gene function and genome evolution. In distantly related genomes, clusters of homologous gene pairs serve as evidence used in function prediction, operon detection, etc. Thus, reliable identification of gene clusters is critical to functional annotation and analysis of genes. I developed an efficient gene clustering algorithm that can be applied on hundreds of genomes at the same time. This approach allows for large-scale study of evolutionary relationships of gene clusters and study of operon formation and destruction. By placing a stricter limit on the maximum cluster size, I developed another algorithm that uses a different formulation based on constraining the overall size of a cluster and statistical estimates that allow direct comparisons of clusters of different size. A comparative analysis of proposed algorithms shows that more biological insight can be obtained by analyzing gene clusters across hundreds of genomes, which can help us understand operon occurrences, gene orientations and gene rearrangements.

Yi, Gang Man

2011-05-01T23:59:59.000Z

422

NIST Forensic Science Research  

Science Conference Proceedings (OSTI)

*. Bookmark and Share. NIST Forensic Science Research. NIST has conducted and supported forensic science research for many decades. ...

2013-09-23T23:59:59.000Z

423

NIST Forensic Science Newsroom  

Science Conference Proceedings (OSTI)

... three publication covers See our latest publications! NIST Forensic Science Newsroom. ... News Archive. NIST Forensic Science News newsletter. ...

2013-10-23T23:59:59.000Z

424

Biology | More Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Bioinformatics Nuclear Medicine Climate and Environment Systems Biology Computational Biology Chemistry Engineering Computer Science Earth and Atmospheric Sciences Materials...

425

NETL: Science Bowl Information  

NLE Websites -- All DOE Office Websites (Extended Search)

Educational Initiatives > Science Bowl Information Educational Initiatives Science Bowl Information Regional Sites Southwestern PA Regional Site West Virginia Regional Site...

426

Genome sequencing and analysis of the model grass Brachypodium distachyon  

NLE Websites -- All DOE Office Websites (Extended Search)

Genome Genome sequencing and analysis of the model grass Brachypodium distachyon The International Brachypodium Initiative* Three subfamilies of grasses, the Ehrhartoideae, Panicoideae and Pooideae, provide the bulk of human nutrition and are poised to become major sources of renewable energy. Here we describe the genome sequence of the wild grass Brachypodium distachyon (Brachypodium), which is, to our knowledge, the first member of the Pooideae subfamily to be sequenced. Comparison of the Brachypodium, rice and sorghum genomes shows a precise history of genome evolution across a broad diversity of the grasses, and establishes a template for analysis of the large genomes of economically important pooid grasses such as wheat. The high-quality genome sequence, coupled with ease of cultivation and transformation, small size and rapid life cycle, will help Brachypodium reach its

427

DOUBLE MAJORS Imaging Science + ...  

E-Print Network (OSTI)

DOUBLE MAJORS Imaging Science + ... Applied Mathematics Biomedical Sciences Computer Science Undergraduate Research Internships and Cooperative Education (Co-op) (optional) Study Abroad WHY IMAGING SCIENCE Science: BS, MS, PhD Color Science: MS, PhD BS + MS/PhD Combos HUMAN VISION BIO- MEDICAL ASTRO- PHYSICS

Zanibbi, Richard

428

FES Science Network Requirements  

E-Print Network (OSTI)

FES Science Network Requirements Report of the Fusion Energy Sciences Network Requirements Workshop Conducted March 13 and 14, 2008 #12;FES Science Network Requirements Workshop Fusion Energy Sciences Program Office, DOE Office of Science Energy Sciences Network Gaithersburg, MD ­ March 13 and 14, 2008 ESnet

Geddes, Cameron Guy Robinson

429

INTEGRATED GENOME-BASED STUDIES OF SHEWANELLA ECOPHYSIOLOGY  

SciTech Connect

This project had as its goals the understanding of the ecophysiology of the genus Shewanella using various genomics approaches. As opposed to other programs involving Shewanella, this one branched out into the various areas in which Shewanella cells are active, and included both basic and applied studies. All of the work was, to some extent, related to the ability of the bacteria to accomplish electron exchange between the cell and solid state electron acceptors and/or electron donors, a process we call Extracellular Electron Transport, or EET. The major accomplishments related to several different areas: Basic Science Studies: 1. Genetics and genomics of nitrate reduction, resulting in elucidation of atypical nitrate reduction systems in Shewanella oneidensis (MR-1)[2]. 2. Influence of bacterial strain and growth conditions on iron reduction, showing that rates of reduction, extents of reduction, and the formation of secondary minerals were different for different strains of Shewanella [3,4,9]. 3. Comparative genomics as a tool for comparing metabolic capacities of different Shewanella strains, and for predicting growth and metabolism [6,10,15]. In these studies, collaboration with ORNL, PNNL, and 4. Basic studies of electron transport in strain MR-1, both to poised electrodes, and via conductive nanowires [12,13]. This included the first accurate measurements of electrical energy generation by a single cell during electrode growth [12], and the demonstration of electrical conductivity along the length of bacterial nanowires [13]. 5. Impact of surface charge and electron flow on cell movement, cell attachment, cell growth, and biofilm formation [7.18]. The demonstration that interaction with solid state electron acceptors resulted in increased motility [7] led to the description of a phenomenon called electrokinesis. The importance of this for biofilm formation and for electron flow was hypothesized by Nealson & Finkel [18], and is now under study in several laboratories. Applications: 1. Corrosion: Electron flow is often part of the corrosive process, and several studies were done in concert with this proposal with regard to the ability of EET-capable bacteria to enhance, inhibit, or detect corrosion. These included using EET-capable bacteria to detect corrosion in its earliest stages [5], to use corrosion-causing bacteria for the study of the microbe/mineral interface during corrosion [1], and to study the groups of microbes involved with corrosion of natural systems [19]. 2. Bioenergy and microbial fuel cells: The production of electricity by Shewanella was shown early in this program (several years ago) to be dependent on the genes for extracellular electron transport (EET), and applied work involved the testing of various strains and conditions for the optimization of current production by the shewanellae [11,14,16]. 3. Identification of shewanellae strains: Based on similarities seen in genomic comparisons, a rapid method was employed for distinguishing between shewanellae strains [17]. Interactions with other laboratories: This grant was an extension of a grant involving the so-called ?Shewanella Federation?, and as such, a number of our publications were joint with other members of this group. The groups included: 1. Pacific Northwest Laboratories ? 2. Oak Ridge National Labs 3. Michigan State University 4. University of Oklahoma 5. Naval Research Laboratory, Washington DC 6. Burnham Medical Research Institute, San Diego 7. J. Craig Venter Institute, San Diego Education: Graduate Students: Michael Waters, Ph.D. ? at NIST, Washington D.C. Lewis Hsu, Ph.D. ? at NRL, San Diego Howard Harris, Ph.D. ? Postdoc at University, France Everett Salas, Ph.D. ? Scientist at Chevron McLean, Jeffrey, Ph.D. ? Scientist at J. Craig Venter Institute McCrow, John, Ph.D. ? Scientist at J. Craig Venter Institute Postdocs: Mohamed El-Naggar ? Professor of Physics, USC Jinjun Kan ? Senior Researcher at Undergraduatges: During this year, we had three undergraduate researchers in the lab, each working on an aspect of this work, and each

NEALSON, KENNETH H.

2013-10-15T23:59:59.000Z

430

Genomics:GTL Bioenergy Research Centers White Paper  

SciTech Connect

In his Advanced Energy Initiative announced in January 2006, President George W. Bush committed the nation to new efforts to develop alternative sources of energy to replace imported oil and fossil fuels. Developing cost-effective and energy-efficient methods of producing renewable alternative fuels such as cellulosic ethanol from biomass and solar-derived biofuels will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy production methods will not suffice. The Genomics:GTL Bioenergy Research Centers will be dedicated to fundamental research on microbe and plant systems with the goal of developing knowledge that will advance biotechnology-based strategies for biofuels production. The aim is to spur substantial progress toward cost-effective production of biologically based renewable energy sources. This document describes the rationale for the establishment of the centers and their objectives in light of the U.S. Department of Energy's mission and goals. Developing energy-efficient and cost-effective methods of producing alternative fuels such as cellulosic ethanol from biomass will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy-production methods will not suffice. The focus on microbes (for cellular mechanisms) and plants (for source biomass) fundamentally exploits capabilities well known to exist in the microbial world. Thus 'proof of concept' is not required, but considerable basic research into these capabilities remains an urgent priority. Several developments have converged in recent years to suggest that systems biology research into microbes and plants promises solutions that will overcome critical roadblocks on the path to cost-effective, large-scale production of cellulosic ethanol and other renewable energy from biomass. The ability to rapidly sequence the DNA of any organism is a critical part of these new capabilities, but it is only a first step. Other advances include the growing number of high-throughput techniques for protein production and characterization; a range of new instrumentation for observing proteins and other cell constituents; the rapid growth of commercially available reagents for protein production; a new generation of high-intensity light sources that provide precision imaging on the nanoscale and allow observation of molecular interactions in ultrafast time intervals; major advances in computational capability; and the continually increasing numbers of these instruments and technologies within the national laboratory infrastructure, at universities, and in private industry. All these developments expand our ability to elucidate mechanisms present in living cells, but much more remains to be done. The Centers are designed to accomplish GTL program objectives more rapidly, more effectively, and at reduced cost by concentrating appropriate technologies and scientific expertise, from genome sequence to an integrated systems understanding of the pathways and internal structures of microbes and plants most relevant to developing bioenergy compounds. The Centers will seek to understand the principles underlying the structural and functional design of selected microbial, plant, and molecular systems. This will be accomplished by building technological pathways linking the genome-determined components in an organism with bioenergy-relevant cellular systems that can be characterized sufficiently to generate realistic options for biofuel development. In addition, especially in addressing what are believed to be nearer-term approaches to renewable energy (e.g., producing cellulosic ethanol cost-effectively and energy-efficiently), the Center research team must understand in depth the current industrial-level roadblocks and bottlenecks (see section, GTL's Vision for Biological Energy Alternatives, below). For the Centers, and indeed the entire BER effort, to be successful, Center research must be integrated with individual investigator research, and coordina

Mansfield, Betty Kay [ORNL; Alton, Anita Jean [ORNL; Andrews, Shirley H [ORNL; Bownas, Jennifer Lynn [ORNL; Casey, Denise [ORNL; Martin, Sheryl A [ORNL; Mills, Marissa [ORNL; Nylander, Kim [ORNL; Wyrick, Judy M [ORNL; Drell, Dr. Daniel [Office of Science, Department of Energy; Weatherwax, Sharlene [U.S. Department of Energy; Carruthers, Julie [U.S. Department of Energy

2006-08-01T23:59:59.000Z

431

Genomics:GTL Bioenergy Research Centers White Paper  

DOE Green Energy (OSTI)

In his Advanced Energy Initiative announced in January 2006, President George W. Bush committed the nation to new efforts to develop alternative sources of energy to replace imported oil and fossil fuels. Developing cost-effective and energy-efficient methods of producing renewable alternative fuels such as cellulosic ethanol from biomass and solar-derived biofuels will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy production methods will not suffice. The Genomics:GTL Bioenergy Research Centers will be dedicated to fundamental research on microbe and plant systems with the goal of developing knowledge that will advance biotechnology-based strategies for biofuels production. The aim is to spur substantial progress toward cost-effective production of biologically based renewable energy sources. This document describes the rationale for the establishment of the centers and their objectives in light of the U.S. Department of Energy's mission and goals. Developing energy-efficient and cost-effective methods of producing alternative fuels such as cellulosic ethanol from biomass will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy-production methods will not suffice. The focus on microbes (for cellular mechanisms) and plants (for source biomass) fundamentally exploits capabilities well known to exist in the microbial world. Thus 'proof of concept' is not required, but considerable basic research into these capabilities remains an urgent priority. Several developments have converged in recent years to suggest that systems biology research into microbes and plants promises solutions that will overcome critical roadblocks on the path to cost-effective, large-scale production of cellulosic ethanol and other renewable energy from biomass. The ability to rapidly sequence the DNA of any organism is a critical part of these new capabilities, but it is only a first step. Other advances include the growing number of high-throughput techniques for protein production and characterization; a range of new instrumentation for observing proteins and other cell constituents; the rapid growth of commercially available reagents for protein production; a new generation of high-intensity light sources that provide precision imaging on the nanoscale and allow observation of molecular interactions in ultrafast time intervals; major advances in computational capability; and the continually increasing numbers of these instruments and technologies within the national laboratory infrastructure, at universities, and in private industry. All these developments expand our ability to elucidate mechanisms present in living cells, but much more remains to be done. The Centers are designed to accomplish GTL program objectives more rapidly, more effectively, and at reduced cost by concentrating appropriate technologies and scientific expertise, from genome sequence to an integrated systems understanding of the pathways and internal structures of microbes and plants most relevant to developing bioenergy compounds. The Centers will seek to understand the principles underlying the structural and functional design of selected microbial, plant, and molecular systems. This will be accomplished by building technological pathways linking the genome-determined components in an organism with bioenergy-relevant cellular systems that can be characterized sufficiently to generate realistic options for biofuel development. In addition, especially in addressing what are believed to be nearer-term approaches to renewable energy (e.g., producing cellulosic ethanol cost-effectively and energy-efficiently), the Center research team must understand in depth the current industrial-level roadblocks and bottlenecks (see section, GTL's Vision for Biological Energy Alternatives, below). For the Centers, and indeed the entire BER effort, to be successful, Center research must be integrated with individual investigator research, and coordination of activities,

Mansfield, Betty Kay [ORNL; Alton, Anita Jean [ORNL; Andrews, Shirley H [ORNL; Bownas, Jennifer Lynn [ORNL; Casey, Denise [ORNL; Martin, Sheryl A [ORNL; Mills, Marissa [ORNL; Nylander, Kim [ORNL; Wyrick, Judy M [ORNL; Drell, Dr. Daniel [Office of Science, Department of Energy; Weatherwax, Sharlene [U.S. Department of Energy; Carruthers, Julie [U.S. Department of Energy

2006-08-01T23:59:59.000Z

432

Information on a Major New Initiative: Mapping and Sequencing the Human Genome (1986 DOE Memorandum)  

DOE R&D Accomplishments (OSTI)

In the history of the Human Genome Program, Dr. Charles DeLisi and Dr. Alvin Trivelpiece of the Department of Energy (DOE) were instrumental in moving the seeds of the program forward. This May 1986 memo from DeLisi to Trivelpiece, Director of DOE's Office of Energy Research, documents this fact. Following the March 1986 Santa Fe workshop on the subject of mapping and sequencing the human genome, DeLisi's memo outlines workshop conclusions, explains the relevance of this project to DOE and the importance of the Department's laboratories and capabilities, notes the critical experience of DOE in managing projects of this scale and potential magnitude, and recognizes the fact that the project will impact biomedical science in ways which could not be fully anticipated at the time. Subsequently, program guidance was further sought from the DOE Health Effects Research Advisory Committee (HERAC) and the April 1987 HERAC report recommended that DOE and the nation commit to a large, multidisciplinary, scientific and technological undertaking to map and sequence the human genome.

DeLisi, Charles (Associate Director, Health and Environmental Research, DOE Office of Energy Research)

1986-05-06T23:59:59.000Z

433

The Human Genome Project: Sequencing the Future  

E-Print Network (OSTI)

. Performance The Office of Science activities target the Secretary's Innovation goal (Lead the world in science to contribute to new strategies for producing new biofuels, cleaning up legacy waste, and sequestering carbon technology, low-enriched uranium (LEU) target technology, LEU solution reactor technology, and neutron

434

Life Sciences Division 2001 Presentations  

E-Print Network (OSTI)

. Uberbacher, "Multiple Gene Finders and their Contribution to our Understanding of the Human Genome

435

Why Sequence the Simplest Cotton Genome?  

NLE Websites -- All DOE Office Websites (Extended Search)

Sequence the Simplest Cotton Genome? Sequence the Simplest Cotton Genome? Cotton is one of the world's most important crops, and it sustains one of the world's largest industries (textiles). The value of cotton fiber and byproducts grown in the USA is typically about $6-7 billion/yr. More than 440,000 domestic jobs are related to cotton processing, with an aggregate influence of ~$120 billion/yr on the US gross domestic product and ~$500 billion/yr worldwide. Increased durability and strength of cotton fiber offers the opportunity to replace synthetic fibers that require more than 200 million barrels of petroleum per year to produce in the USA alone, also increasing use of bio-based products and increasing farm income. Its seed oil, and also byproducts of cotton processing, are potential raw materials

436

Fueling the Future with Fungal Genomics  

SciTech Connect

Fungi play important roles across the range of current and future biofuel production processes. From crop/feedstock health to plant biomass saccharification, enzyme production to bioprocesses for producing ethanol, higher alcohols or future hydrocarbon biofuels, fungi are involved. Research and development are underway to understand the underlying biological processes and improve them to make bioenergy production efficient on an industrial scale. Genomics is the foundation of the systems biology approach that is being used to accelerate the research and development efforts across the spectrum of topic areas that impact biofuels production. In this review, we discuss past, current and future advances made possible by genomic analyses of the fungi that impact plant/feedstock health, degradation of lignocellulosic biomass and fermentation of sugars to ethanol, hydrocarbon biofuels and renewable chemicals.

Grigoriev, Igor V.; Cullen, Daniel; Hibbett, David; Goodwin, Stephen B.; Jeffries, Thomas W.; Kubicek, Christian P.; Kuske, Cheryl; Magnuson, Jon K.; Martin, Francis; Spatafora, Joey; Tsang, Adrian; Baker, Scott E.

2011-04-29T23:59:59.000Z

437

Fueling the future with fungal genomics  

E-Print Network (OSTI)

Fungi play important roles across the range of current and future biofuel production processes. From crop/feedstock health to plant biomass saccharification, enzyme production to bioprocesses for producing ethanol, higher alcohols, or future hydrocarbon biofuels, fungi are involved. Research and development are underway to understand the underlying biological processes and improve them to make bioenergy production efficient on an industrial scale. Genomics is the foundation of the systems biology approach that is being used to accelerate the research and development efforts across the spectrum of topic areas that impact biofuels production. In this review, we discuss past, current, and future advances made possible by genomic analyses of the fungi that impact plant/feedstock health, degradation of lignocellulosic biomass, and fermentation of sugars to ethanol, hydrocarbon biofuels, and renewable chemicals.

Igor V. Grigoriev A; Daniel Cullen B; Stephen B. Goodwin C; David Hibbett D; Thomas W. Jeffries B; Christian P. Kubicek E; Cheryl Kuske F; Jon K. Magnuson G; Francis Martin H; Joseph W. Spatafora I; Adrian Tsang J; Scott E. Baker A

2011-01-01T23:59:59.000Z

438

Comparative proteogenomics: combining mass spectrometry and comparative genomics to analyze multiple genomes  

SciTech Connect

While bacterial genome annotations have significantly improved in recent years, techniques for bacterial proteome annotation (including post-translational chemical modifications, signal peptides, proteolytic events, etc.) are still in their infancy. At the same time, the number of sequenced bacterial genomes is rising sharply, far outpacing our ability to validate the predicted genes, let alone annotate bacterial proteomes. In this study, we use tandem mass spectrometry (MS/MS) to annotate the proteome of Shewanella oneidensis MR-1, an important microbe for bioremediation. In particular, we provide the first comprehensive map of post-translational modifications in a bacterial genome, including a large number of chemical modifications, signal peptide cleavages and cleavage of N-terminal methionine residues. We also detect multiple genes that were missed or assigned incorrect start positions by gene prediction programs and suggest corrections to improve the gene annotation. This study demonstrates that complementing every genome sequencing project by an MS/MS project would significantly improve both genome and proteome annotations for a reasonable cost.

Gupta, Nitin; Benhamida, Jamal; Bhargava, Vipul; Goodman, Daniel; Kain , Elisabeth; Kerman, Ian; Nguyen , Ngan; Ollikainen, Noah; Rodriguez, Jesse; Wang, J.; Lipton, Mary S.; Romine, Margaret F.; Bafna, Vineet; Smith, Richard D.; Pevzner, Pavel A.

2008-07-30T23:59:59.000Z

439

Science Highlights  

NLE Websites -- All DOE Office Websites (Extended Search)

Highlights Highlights Science Highlights Science highlights feature research conducted by staff and users at the ALS. If a Power Point summary slide or a PDF handout of the highlight is available, you will find it linked beneath the highlight listing and on the highlight's page. You may also print a version of a highlight by clicking the print icon associated with each highlight. The Molecular Ingenuity of a Unique Fish Scale Print Monday, 25 November 2013 12:06 ALS research has shown how the scales of a freshwater fish found in the Amazon Basin can literally re-orient themselves in real time to resist force, in essence creating an adaptable body armor. Read more... New Research on Jamming Behavior Expands Understanding Print Tuesday, 22 October 2013 00:00 Recent ALS research has revealed that even magnetic domains behave very much like other granular material systems, and their dynamical behavior mimics the universal characteristics of several jammed systems.

440

Applied Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Applied Science Applied Science Correlation of predicted and measured iron oxidation states in mixed iron oxides H. D. Rosenfeld and W. L. Holstein Development of a quantitative measurement of a diesel spray core using synchrotron x-rays C.F. Powell, Y. Yue, S. Gupta, A. McPherson, R. Poola, and J. Wang Localized phase transformations by x-ray-induced heating R.A. Rosenberg, Q. Ma, W. Farrell, E.D. Crozier, G.J. Soerensen, R.A. Gordon, and D.-T. Jiang Resonant x-ray scattering at the Se edge in ferroelectric liquid crystal materials L. Matkin, H. Gleeson, R. Pindak, P. Mach, C. Huang, G. Srajer, and J. Pollmann Synchrotron-radiation-induced anisotropic wet etching of GaAs Q. Ma, D.C. Mancini, and R.A. Rosenberg Synchrotron-radiation-induced, selective-area deposition of gold on

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Applied Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Geological Sciences Geological Sciences Atomic-scale structure of the orthoclase (001)-water interface measured with high-resolution x-ray reflectivity P. Fenter, H. Teng, P. Geissbühler, J.M. Hanchar, K.L. Nagy, and N.C. Sturchio Chemical analysis of individual interplanetary dust particles G.J. Flynn, S.R. Sutton, M. Rivers, P. Eng, and M. Newville Diffusion-limited biotransformation of metal contaminants in soils/sediments: chromium T. Tokunaga, J. Wan, D. Joyner, T. Hazen, M. Firestone, E. Schwartz, S. Sutton, and M. Newville Investigation of meteorite porosity by computed microtomography G.J. Flynn, M. Rivers, and S.R. Sutton Microscale imaging of pore structure in hydrothermal sulfide chimneys using synchrotron x-ray computed tomography P. O'Day, J. Muccino, S. Thompson, M.Jew, and J. Holloway

442

[Faculty of Science Information and Computing Sciences  

E-Print Network (OSTI)

and Computing Sciences] 7 Combinators data I r = I r data K a r = K a data U r = U -- for constructors) Fix f r fold alg (In f) = alg (fmap (fold alg) f) #12;[Faculty of Science Information and Computing;[Faculty of Science Information and Computing Sciences] 17 Representing a family data ExprF (r :: ) (ix

Löh, Andres

443

[Faculty of Science Information and Computing Sciences  

E-Print Network (OSTI)

[Faculty of Science Information and Computing Sciences] Generic diff Andres Löh joint work with Eelco Lempsink and Sean Leather Dept. of Information and Computing Sciences, Utrecht University IFIP WG 2.1 meeting #64, Weltenburg, April 2, 2009 #12;[Faculty of Science Information and Computing

Löh, Andres

444

Past Science Advisors Early Science Advisors  

E-Print Network (OSTI)

NSTC NNSA with R&D agencies Science and Technology in the U.S. GovernmentScience and Technology Transportation Defense Energy NSF-36 NIH USGS NOAA NIST Homeland Security DARPA, ONR, AFOSR NSTC NNSA Science NIST Homeland Security DARPA, ONR, AFOSR NSTC NNSA Science and Technology are important to most Federal

Colorado at Boulder, University of

445

POLITICAL SCIENCE Political science is the study  

E-Print Network (OSTI)

POLITICAL SCIENCE Political science is the study of governments, public policies, and political behavior. Political science uses both humanistic perspectives and scientific skills to examine the United States and all countries and regions of the world. Students enrolled in Political Science courses explore

446

Web of Science Welcome to the Web of Science................................................................................................ 2  

E-Print Network (OSTI)

Web of Science #12; Welcome to the Web of Science................................................................................................ 2 Web of Science.................................................................................................................. 4 ISI Web of Knowledge

Huang, Su-Yun

447

Comparative Genomics Analysis and Phenotypic Characterization of Shewanella putrefaciens W3-18-1: Anaerobic Respiration, Bacterial Microcompartments, and Lateral Flagella  

E-Print Network (OSTI)

Comparative genomics analysis and phenotypicfor Environmental Genomics, University of Okalahoma, Norman,Table 1 Comparative genomics analyses of components of

Qiu, D.

2010-01-01T23:59:59.000Z

448

EST_GENOME: a program to align spliced DNA sequences to unspliced genomic DNA  

E-Print Network (OSTI)

spliced DNA to unspliced genomic DNA. It is written in ANSI C and has been tested under Digital OSF3.2. The spurce code and documentation are available from ftp:// www.sanger.ac.uky ftp/pub / badger/est_genome.2.tar.Z. The prediction of genes in uncharacterized genomic DNA sequence is currently one of the main problems facing sequence annotators. Methods based on de novo prediction, e.g. searching for motifs like the splice-site consensus, or on statistical properties such as biased codon usage, etc. (Solovyev et al., 1994; Hebsgaard et al., 1996) have been only partially successful, and investigators have often found that the surest way of predicting a gene is by alignment with a homologous protein sequence (Birney et al., 1996; Gelfand et al., 1996; Huang and Zhang, 1996), or a spliced gene product [an expressed sequence tag (EST), mRNA or cDNA],

Richard Mott

1997-01-01T23:59:59.000Z

449

Behavioral Sciences | ornl.gov  

NLE Websites -- All DOE Office Websites (Extended Search)

Chemistry Computational Engineering Computer Science Data Earth Sciences Energy Science Future Technology Knowledge Discovery Materials Mathematics National Security Systems...

450

Materials Science | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Economy Funding Opportunities State & Local Government Science & Innovation Science & Technology Science Education Innovation Energy Sources Energy Usage Energy Efficiency...

451

Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study  

E-Print Network (OSTI)

USA. 19 Office of Population Genomics, National Human GenomeArchitecture using Genomics and Epidemiology (PAGE) Study.Architecture using Genomics and Epidemiology (PAGE) study.

2013-01-01T23:59:59.000Z

452

Genomic Speciation and Adaptation in Aquilegia (2011 JGI User Meeting)  

Science Conference Proceedings (OSTI)

The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Scott Hodges of the University of California, Santa Barbara gives a presentation on "Genomic Speciation and Adaptation in Aquilegia" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

Hodges, Scott [University of California, Santa Barbara

2011-03-23T23:59:59.000Z

453

Genomics of Extinct and Endangered Species (2011 JGI User Meeting)  

Science Conference Proceedings (OSTI)

The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Stephen Shuster of Penn State University gives a presentation on "Genomics of Extinct and Endangered Species" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

Shuster, Stephen [Penn State University

2011-03-23T23:59:59.000Z

454

ORISE: Center for Science Education  

NLE Websites -- All DOE Office Websites (Extended Search)

Center for Science Education ORAU Center for Science Education ORAU Center for Science Education Completed in January 2009, the Center for Science Education was established to...

455

Science DMZ Implemented at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

ESnet Overview ESnet Staff Governance Our Network Case Studies OSCARS Case Studies Science DMZ Case Studies Science DMZ CU Science DMZ Penn State & VTTI Science DMZ NOAA...

456

Publications of the Life Sciences Division, ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

LSD logo Life Sciences Division LSD logo Life Sciences Division Oak Ridge National Laboratory Programs Partners Organization Highlights In the News --- Home Internal (Restricted Access) Contacts Publications 2003 Publications/Presentations Akabani, G., S. J. Kennel, and M. R. Zalutsky, "Microdosimetric analysis of alpha-particle-emitting targeted radiotherapeutics using histological images," J. Nucl. Med. 44(5):792-805 (May 2003). Allain, L. R., D. N. Stratis, C. M. Cullum, J. Mobley, M. R. Hajaligol, and T. Vo-Dinh, "Real-time detection of PAH mixtures in the vapor phase at high temperatures," J. Anal. Appl. Pyrolysis 66(1-2):145-154 (January 2003). Chain, P., J. Lamerdin, F. Larimer, W. Regala, V. Lao, M. Land, L. Hauser, A. Hooper, M. Klotz, J. Norton, L. Sayavedra- Soto, D. Arciero, N. Hommes, M. Whittaker, and D. Arp, "Complete Genome Sequence of the Ammonia-Oxidizing Bacterium and Obligate Chemolithoautotroph NitrosomonaseEuropaea," J. Bacteriology 185(9):2759-2773 (May 2003).

457

Fueling the Future with Fungal Genomics  

E-Print Network (OSTI)

yeast for improved biofuel production. Science. 330:84-86.current and future biofuel production processes. From crop/platforms for biomass-to-biofuel production on an industrial

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

458

Supercomputing | Computer Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Resilience Engineering of Scientific Software Translation Quantum Computing Machine Learning Information Retrieval Content Tagging Visual Analytics Data Earth Sciences Energy Science Future Technology Knowledge Discovery Materials Mathematics National Security Systems Modeling Engineering Analysis Behavioral Sciences Geographic Information Science and Technology Quantum Information Science Supercomputing and Computation Home | Science & Discovery | Supercomputing and Computation | Research Areas | Computer Science SHARE Computer Science Computer Science at ORNL involves extreme scale scientific simulations through research and engineering efforts advancing the state of the art in algorithms, programming environments, tools, and system software. ORNL's work is strongly motivated by, and often carried out in direct

459

Facilities | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Facilities Facilities Biological and Environmental Research (BER) BER Home About Research Facilities DOE Joint Genome Institute (JGI) ARM Climate Research Facility Environmental Molecular Sciences Laboratory Facility Metrics Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) News & Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301) 903-5051 E: sc.ber@science.doe.gov More Information » Facilities Print Text Size: A A A RSS Feeds FeedbackShare Page BER User Facilities DOE designs, develops, builds, and operates unique, world-class facilities for the benefit of the entire research community. DOE Office of Science

460

Towards a Library of Standard Operating Procedures (SOPs) for (meta)genomic annotation  

SciTech Connect

Genome annotations describe the features of genomes and accompany sequences in genome databases. The methodologies used to generate genome annotation are diverse and typically vary amongst groups. Descriptions of the annotation procedure are helpful in interpreting genome annotation data. Standard Operating Procedures (SOPs) for genome annotation describe the processes that generate genome annotations. Some groups are currently documenting procedures but standards are lacking for structure and content of annotation SOPs. In addition, there is no central repository to store and disseminate procedures and protocols for genome annotation. We highlight the importance of SOPs for genome annotation and endorse a central online repository of SOPs.

Kyrpides, Nikos; Angiuoli, Samuel V.; Cochrane, Guy; Field, Dawn; Garrity, George; Gussman, Aaron; Kodira, Chinnappa D.; Klimke, William; Kyrpides, Nikos; Madupu, Ramana; Markowitz, Victor; Tatusova, Tatiana; Thomson, Nick; White, Owen

2008-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

GLAMM: Genome-Linked Application for Metabolic Maps  

SciTech Connect

The Genome-Linked Application for Metabolic Maps (GLAMM) is a unified web interface for visualizing metabolic networks, reconstructing metabolic networks from annotated genome data, visualizing experimental data in the context of metabolic networks, and investigating the construction of novel, transgenic pathways. This simple, user-friendly interface is tightly integrated with the comparative genomics tools of MicrobesOnline. GLAMM is available for free to the scientific community at glamm.lbl.gov.

Bates, John; Chivian, Dylan; Arkin, Adam

2011-05-29T23:59:59.000Z

462

Complete genome sequence of Methanoculleus marisnigri type strain JR1  

SciTech Connect

Methanoculleus marisnigri Romesser et al. 1981 is a methanogen belonging to the order Methanomicrobiales within the archaeal phylum Euryarchaeota. The type strain, JR1, was isolated from anoxic sediments of the Black Sea. M. marisnigri is of phylogenetic interest because at the time the sequencing project began only one genome had previously been sequenced from the order Methanomicrobiales. We report here the complete genome sequence of M. marisnigri type strain JR1 and its annotation. This is part of a Joint Genome Institute 2006 Community Sequencing Program to sequence genomes of diverse Archaea.

Anderson, Iain [U.S. Department of Energy, Joint Genome Institute; Sieprawska-Lupa, Magdalena [University of Georgia, Athens, GA; Goltsman, Eugene [U.S. Department of Energy, Joint Genome Institute; Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Tice, Hope [U.S. Department of Energy, Joint Genome Institute; Dalin, Eileen [U.S. Department of Energy, Joint Genome Institute; Barry, Kerrie [U.S. Department of Energy, Joint Genome Institute; Saunders, Elizabeth H [Los Alamos National Laboratory (LANL); Han, Cliff [Los Alamos National Laboratory (LANL); Brettin, Tom [Los Alamos National Laboratory (LANL); Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Bruce, David [Los Alamos National Laboratory (LANL); Mikhailova, Natalia [U.S. Department of Energy, Joint Genome Institute; Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Hauser, Loren John [ORNL; Land, Miriam L [ORNL; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Richardson, P M [U.S. Department of Energy, Joint Genome Institute; Whitman, W. B. [University of Georgia, Athens, GA; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute

2009-01-01T23:59:59.000Z

463

Complete genome sequence of Methanocorpusculum labreanum type strain Z  

Science Conference Proceedings (OSTI)

Methanocorpusculum labreanum is a methanogen belonging to the order Methanomicrobiales within the archaeal phylum Euryarchaeota. The type strain Z was isolated from surface sediments of Tar Pit Lake in the La Brea Tar Pits in Los Angeles, California. M. labreanum is of phylogenetic interest because at the time the sequencing project began only one genome had previously been sequenced from the order Methanomicrobiales. We report here the complete genome sequence of M. labreanum type strain Z and its annotation. This is part of a 2006 Joint Genome Institute Community Sequencing Program project to sequence genomes of diverse Archaea.

Anderson, Iain [U.S. Department of Energy, Joint Genome Institute; Sieprawska-Lupa, Magdalena [University of Georgia, Athens, GA; Goltsman, Eugene [U.S. Department of Energy, Joint Genome Institute; Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Tice, Hope [U.S. Department of Energy, Joint Genome Institute; Dalin, Eileen [U.S. Department of Energy, Joint Genome Institute; Barry, Kerrie [U.S. Department of Energy, Joint Genome Institute; Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Hauser, Loren John [ORNL; Land, Miriam L [ORNL; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Richardson, P M [U.S. Department of Energy, Joint Genome Institute; Whitman, W. B. [University of Georgia, Athens, GA; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute

2009-01-01T23:59:59.000Z

464

A Celebration of The Genome, 1953-2003  

Office of Scientific and Technical Information (OSTI)

the historic culmination of one of the most important scientific projects in history, the sequencing of the human genome, and the 50th anniversary of James Watson and...

465

Genomic Sequencing of Single Bacterial Cells (2010 JGI User Meeting)  

SciTech Connect

Tanja Woyke from the DOE JGI on the "Genomic Sequencing of Single Bacterial Cells" on March 26, 2010 at the 5th Annual DOE JGI User Meeting

Woyke, Tanje

2010-03-26T23:59:59.000Z

466

EA-1065: Proposed Construction and Operation of a Genome Sequencing...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

65: Proposed Construction and Operation of a Genome Sequencing Facility in Building 64 at Lawrence Berkeley Laboratory, Berkeley, California EA-1065: Proposed Construction and...

467

Low Dose Radiation Research Program: Induction of Genomic Instability...  

NLE Websites -- All DOE Office Websites (Extended Search)

Brook Why This Project Genomic instability is an important step in radiation-induced cancer. We will investigate one potential repair mechanism involved in radiation-induced...

468

Fast Identification of Gene Clusters in Prokaryotic Genomes ... - CECM  

E-Print Network (OSTI)

linear space practical complexity. The number of clusters for the data set of 12 genomes goes from 199 clusters (? = 3, ? = 2. and ? = 100) to 930 clusters (? = 2, ...

469

DOE Joint Genome Institute: Exploring Standards to Advance Microbial...  

NLE Websites -- All DOE Office Websites (Extended Search)

July 9, 2009 Exploring Standards to Advance Microbial Genomics WALNUT CREEK, CA-Microbes contribute to manifold human endeavors ranging from bioenergy to agriculture to medicine....

470

DOE Joint Genome Institute: Up from the Depths: How Bacteria...  

NLE Websites -- All DOE Office Websites (Extended Search)

to verify the predominant bacterial lineages capable of trapping carbon in this deep underwater region. "This study represents a pristine example for the use of single cell genome...

471

DOE human genome program contractor-grantee workshop VI  

SciTech Connect

Research is presented from the workshop on the Human Genome Project. Topics include sequencing, genetic mapping, informatics, ethical and legal issues, and infrastructure.

NONE

1997-10-01T23:59:59.000Z

472

Low Dose Radiation Research Program: Genomic Instability and...  

NLE Websites -- All DOE Office Websites (Extended Search)

Genomic Instability and Low Dose Low Dose Rate Radiation. Authors: Lei Huang, Suzanne Grim, William F. Morgan Institutions: University of Maryland. Humans will always receive...

473

Low Dose Radiation Research Program: Induction of Genomic Instability...  

NLE Websites -- All DOE Office Websites (Extended Search)

lesions in the progeny of exposed cells for several cell generations following irradiation. It has been hypothesized that genomic instability is a key event in the...

474

Contribution of Tissue Level Organization to Genomic Stability...  

NLE Websites -- All DOE Office Websites (Extended Search)

of Tissue Level Organization to Genomic Stability Following Low Dose Gamma Irradiation Cheryl Burrell Loma Linda University Abstract Our study proposes that the level of...

475

Joint Genome Institute Progress Report 2002-2005  

SciTech Connect

Progress report covering activities at the DOE-Joint Genome Institute in Walnut Creek, California for the period 2002-2005.

Gilbert, David

2005-10-03T23:59:59.000Z

476

Complete genome sequence of Acidimicrobium ferrooxidans type strain (ICPT)  

Science Conference Proceedings (OSTI)

Acidimicrobium ferrooxidans (Clark and Norris 1996) is the sole and type species of the genus, which until recently was the only genus within the actinobacterial family Acidimicrobiaceae and in the order Acidomicrobiales. Rapid oxidation of iron pyrite during autotrophic growth in the absence of an enhanced CO2 concentration is characteristic for A. ferrooxidans. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first complete genome sequence of the order Acidomicrobiales, and the 2,158,157 bp long single replicon genome with its 2038 protein coding and 54 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Clum, Alicia; Nolan, Matt; Lang, Elke; Glavina Del Rio, Tijana; Tice, Hope; Copeland, Alex; Cheng, Jan-Fang; Lucas, Susan; Chen, Feng; Bruce, David; Goodwin, Lynne; Pitluck, Sam; Ivanova, Natalia; Mavrommatis, Konstantinos; Mikhailova, Natalia; Pati, Amrita; Chen, Amy; Palaniappan, Krishna; Goker, Markus; Spring, Stefan; Land, Miriam; Hauser, Loren; Chang, Yun-Juan; Jefferies, Cynthia C.; Chain, Patrick; Bristow, James; Eisen, Jonathan A.; Markowitz, Victor; Hugenholtz, Philip; Kyrpides, Nikos C.; Klenk, Hans-Peter; Lapidus, Alla

2009-05-20T23:59:59.000Z

477

DOE Joint Genome Institute: IMG ER Goes Primetime: Provides Expert...  

NLE Websites -- All DOE Office Websites (Extended Search)

that regulate our environment. Scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) and the Biological Data Management and Technology Center...

478

Chloroplast DNA insertions into the nuclear genome of rice: the ...  

Science Conference Proceedings (OSTI)

Shahmuradov IA, Akbarova YY, Solovyev VV, Aliye JA (2003). Abundance of plastid DNA insertions in nuclear genomes of rice and Arabidopsis. Plant Mol Biol...

479

The Oak Ridge Genome Annotation and Analysis Pipelines  

NLE Websites -- All DOE Office Websites (Extended Search)

Grail (Microbial Gene Prediction System Internet Link) GrailEXP Genome Analysis Pipeline DomainParser PROSPECT (PROtein Structure Prediction and Evaluation Computer...

480

Whole-genome shotgun optical mapping of rhodospirillum rubrum  

E-Print Network (OSTI)

of the University of Wisconsin-Madison Laboratory forComputational Genomics, University of Wisconsin- Madison,Madison, Wisconsin 53706 USA; 2 Department of Chemistry,

2004-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "bssd genomic science" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Analysis of human mRNAs with the reference genome sequence reveals potent errors, polymorphisms, and RNA editing  

E-Print Network (OSTI)

977. International Human Genome Sequencing Consortium 2001.Res. 32: D32D34. Mouse Genome Sequencing Consortium 2002.95064, USA; 2 Genome Sequencing Center, Washington

2004-01-01T23:59:59.000Z

482

Comparative genomics and natural distributions of phenotypically distinct strains of the nitrogen-fixing cyanobacterium Crocosphaera watsonii  

E-Print Network (OSTI)

Where genetics meets genomics. Nat. Rev. Genet. 3, 329-341.cyanobacterium. BMC Genomics 9, 274. Goericke, R. , andF. (2009). Ecological Genomics of Marine Picocyanobacteria.

Bench, Shellie

2012-01-01T23:59:59.000Z

483

The Comparative Genomics of Salinispora and the Distribution and Abundance of Secondary Metabolite Genes in Marine Plankton  

E-Print Network (OSTI)

Buchan A (2007) Ecological Genomics of Marine Roseobacters.biology and comparative genomics. BMC Bioinformatics 10(1):SAN DIEGO The Comparative Genomics of Salinispora and the

Penn, Kevin Matthew

2012-01-01T23:59:59.000Z

484

Functional genomics of the bacterial degradation of the emerging water contaminants: 1,4-dioxane and N-nitrosodimethylamine (NDMA)  

E-Print Network (OSTI)

database: A comprehensive genomics resource on microbialtherefore functional genomics approaches that marry theFunctional genomics of the bacterial degradation of the

Sales, Christopher Michael

2012-01-01T23:59:59.000Z

485

Comparative genomics of citric-acid producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88  

E-Print Network (OSTI)

expression profiles. Mol. Genet. Genomics 279:Comparative genomics of citric-acid producing Aspergillus2006. Aspergillusnigergenomics:past,presentandinto

Grigoriev, Igor V.

2011-01-01T23:59:59.000Z

486

NREL: Energy Sciences - Theoretical Materials Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Computational Materials Science Solid-State Theory Materials Science Hydrogen Technology & Fuel Cells Process Technology & Advanced Concepts Research Staff Computational Science Printable Version Theoretical Materials Science Learn about our research staff including staff profiles, publications, and contact information. Using modern computational techniques, the Theoretical Materials Science Group, within NREL's Chemical and Materials Science Center, applies quantum mechanics to complex materials, yielding quantitative predictions to guide and interact with experimental explorations. Current research focuses on the following efforts: Design new photovoltaic materials that can improve solar cell efficiency and reduce its cost. Explain the underlying physics of new

487

Biological Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Science Biological Science A unique zinc-binding site revealed by the high-resolution x-ray structure of homotrimeric Apo2L/TRAIL S.G. Hymowitz, M.P. O'Connell, M.H. Ultsch, A. Hurst, K. Totpal, A. Ashkenazi, R.F. Kelley, and A.M. de Vos b-carbonic anhydrase active site architecture is a mirror image of a-carbonic anhydrases E.F. Pai and M.S. Kimber Binding of Cd ions to the cell wall of B. Subtilis - an EXAFS study M. Boyanov, D. Fowle, K. Kemner, B. Bunker, and J. Fein Crystallographic evidence for Try157 functioning as the active site base in human UDP-galactose 4-epimerase J.B. Thoden, T.M. Wohlers, J.L. Fridovich-Keil, and H.M. Holden Crystallographic studies of dsDNA phage HK97 structure and maturation W.R. Wikoff, Z. Che, W. Schildkamp, L. Liljas, R.L. Duda, R.W. Hendrix, and

488

Chemical Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Chemical Science Chemical Science Compton double ionization of helium in the region of the cross-section maximum B. Krässig, R.W. Dunford, D.S. Gemmell, S. Hasegawa, E.P. Kanter, H. Schmidt-Böcking, W. Schmitt, S.H. Southworth, Th. Weber, and L. Young Crystal structure analysis of microporous Na16Nb12.8Ti3.2O44.8(OH)3.2l8H2O and Na/Nb/Zr/O/H2O phases A. Tripathi, J. Parise, M. Nyman, T.M. Nenoff, and W. Harrison Double K-photoionization of heavy atoms R.W. Dunford, D.S. Gemmell, E.P. Kanter, B. Krässig, and S.H. Southworth Forward-backward asymmetries of atomic photoelectrons S.H. Southworth, B. Krässig, E.P. Kanter, J.C. Bilheux, R.W. Dunford, D.S. Gemmell, S. Hasegawa, and L. Young In situreduction of various iron oxides to form high-surface-area Fe-metal catalysts as studied by high-resolution powder diffraction

489

Genomic and Genetic Approaches to Solvent Tolerance  

DOE Green Energy (OSTI)

The proposed research is to understand and exploit the molecular basis that determines tolerance of the industrially important anaerobic clostridia to solvents. Furthermore, we aim to develop general genomic and metabolic engineering strategies for understanding the molecular basis of tolerance to chemicals and for developing tolerant strains. Our hypothesis is that the molecular basis of what makes bacterial cells able to withstand high solvent concentrations can be used to metabolically engineer cells so that they can tolerate higher concentrations of solvents and related chemicals.

Eleftherios T. Papoutsakis

2005-06-10T23:59:59.000Z

490

E-Science Day  

E-Print Network (OSTI)

on December 6, 2011, E-Science Day was a day-long event,regional librarians in e-science, and to expose regionalthe initiation of e-science support projects within their

Abad, Raquel

2012-01-01T23:59:59.000Z

491

Communicating Evolution as Science  

E-Print Network (OSTI)

thuringiensis toxins. Science. 1992;258(5087):14515. MillerRT, Ruse M. But is it science? Amherst, NY: Prometheusto the philosophy of science: theory and reality. Chicago:

Thanukos, Anastasia

2010-01-01T23:59:59.000Z

492

BES Science Network Requirements  

E-Print Network (OSTI)

the Directors of the Office of Science, Office of AdvancedOffice of Basic Energy Sciences. This is LBNL report LBNL-BES Science Network Requirements Report of the Basic Energy

Dart, Eli

2011-01-01T23:59:59.000Z

493

Science-Driven Network  

NLE Websites -- All DOE Office Websites (Extended Search)

Science-Driven Network Requirements for ESnet Update to the 2002 Office of Science Networking Requirements Workshop Report February 21, 2006 1-1 Science-Driven Network Requirements...

494

doi:10.1093/nar/gkr947 The Genome Portal of the Department of Energy Joint Genome Institute  

E-Print Network (OSTI)

The Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility with massive-scale DNA sequencing and analysis capabilities dedicated to advancing genomics for bioenergy and environmental applications. Beyond generating tens of trillions of DNA bases annually, the Institute develops and maintains data management systems and specialized analytical capabilities to manage and interpret complex genomic data sets, and to enable an expanding community of users around the world to analyze these data in different contexts over the web. The JGI Genome Portal

Igor V. Grigoriev; Henrik Nordberg; Igor Shabalov; Andrea Aerts; Mike Cantor; David Goodstein; Alan Kuo; Simon Minovitsky; Roman Nikitin; Robin A. Ohm; Robert Otillar; Alex Poliakov; Igor Ratnere; Robert Riley; Tatyana Smirnova; Daniel Rokhsar; Inna Dubchak

2011-01-01T23:59:59.000Z

495

Basic Energy Sciences  

Office of Science (SC) Website

http:science.energy.govbesaboutjobs Below is a list of currently open federal employment opportunities in the Office of Science. Prospective applicants should follow the...

496

Fusion Energy Sciences  

Office of Science (SC) Website

http:science.energy.govfesaboutjobs Below is a list of currently open federal employment opportunities in the Office of Science. Prospective applicants should follow the...

497

BNL | Computational Science Center  

NLE Websites -- All DOE Office Websites (Extended Search)

Computational Science Center Home Research Support Areas Publications Staff EBC Environmental, Biological, and Computational Sciences Directorate CSC image CSC image CSC image CSC...

498

Lederman Science Center  

NLE Websites -- All DOE Office Websites (Extended Search)

Lederman Science Center: Fermilab Science for Kids and Educators LSC Home Plan a Visit DirectionsMap Exhibits: Overview - List - Physics Playground LSC Floorplan LSC Store...

499

Energy Science at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

Artificial Photosynthesis II - EFRC Carbon Capture and Sequestration Activities at NERSC Novel Methods for Harvesting Solar Energy Engineering Science Environmental Science Fusion...

500

Life Sciences News  

Science Conference Proceedings (OSTI)

... Life Sciences News. ... may be within reach of every doctor's office if recent ... NIST Center for Nanoscale Science and Technology researchers Gregg ...

2010-05-24T23:59:59.000Z