Sample records for bssd genomic science

  1. CROP & SOIL SCIENCES Quantitative Genomics

    E-Print Network [OSTI]

    Arnold, Jonathan

    CROP & SOIL SCIENCES Quantitative Genomics Committee Membership Dr. Scott Jackson - committee chair Dr. Peng-Wah Chee Department of Crop & Soil Sciences Department of Crop & Soil Sciences University of Horticulture Department of Crop & Soil Sciences University of Georgia University of Georgia 2360 Rainwater Rd

  2. Biological Systems Science Division (BSSD) | U.S. DOE Office of Science

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 Industrial CarbonArticlesHumanJune 2008 Basic EnergyB.Bette Korber, 2004 TheStaff

  3. Genome Science/Technologies

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genome Genome

  4. Genome Science and Personalized Cancer Treatment

    ScienceCinema (OSTI)

    Joe Gray

    2010-01-08T23:59:59.000Z

    August 4, 2009 Berkeley Lab lecture: Results from the Human Genome Project are enabling scientists to understand how individual cancers form and progress. This information, when combined with newly developed drugs, can optimize the treatment of individual cancers. Joe Gray, director of Berkeley Labs Life Sciences Division and Associate Laboratory Director for Life and Environmental Sciences, will focus on this approach, its promise, and its current roadblocks ? particularly with regard to breast cancer.

  5. Genomic Sciences | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genome

  6. Public Health Genomics Population Health Sciences 650 Section 023

    E-Print Network [OSTI]

    Sheridan, Jennifer

    Public Health Genomics Population Health Sciences 650 Section 023 Summer 2009, 07/20/09 ­ 07: Public health genomics is a new discipline that uses knowledge gained from genetic and molecular research and the social sciences, and much more. This course will provide 1) an introduction to public health genomics, 2

  7. 684 journal of law, medicine & ethics he new science of genomics endeavors to

    E-Print Network [OSTI]

    Church, George M.

    684 journal of law, medicine & ethics T he new science of genomics endeavors to chart the genomes and develop- ing countries, the promises and perils of genomic science appear against a backdrop of global attempting to decide about participating in genomic research or any other biomedical research. Genomic

  8. The Plant Genome [A Supplement to Crop Science] March 2008 No. 1 S-27 Genomic Origins of Potato

    E-Print Network [OSTI]

    Spooner, David

    The Plant Genome [A Supplement to Crop Science] March 2008 No. 1 S-27 Genomic Origins of Potato., and Shelley H. Jansky Abstract Chromosome pairing relationships within cultivated potato (Solanum tuberosum we reexamine potato genome hypotheses with the first phylogenetic analysis of all major genomes

  9. Genome Science and Personalized Cancer Treatment (LBNL Summer Lecture Series)

    ScienceCinema (OSTI)

    Gray, Joe

    2011-04-28T23:59:59.000Z

    Summer Lecture Series 2009: Results from the Human Genome Project are enabling scientists to understand how individual cancers form and progress. This information, when combined with newly developed drugs, can optimize the treatment of individual cancers. Joe Gray, director of Berkeley Labs Life Sciences Division and Associate Laboratory Director for Life and Environmental Sciences, will focus on this approach, its promise, and its current roadblocks ? particularly with regard to breast cancer.

  10. Proceedings of the Sudden Oak Death Third Science Symposium Mitochondrial Genomics in the Genus

    E-Print Network [OSTI]

    Standiford, Richard B.

    Proceedings of the Sudden Oak Death Third Science Symposium 243 Mitochondrial Genomics in the Genus The mitochondrial genomes of Phytophthora infestans, P. ramorum and P. sojae have been sequenced and comparative genomics has provided an opportunity to examine the processes involved with genome evolution in the genus

  11. Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum

    E-Print Network [OSTI]

    Ditty, Jayna L.

    2012-01-01T23:59:59.000Z

    Page Incorporating Genomics and Bioinformatics across the2007) Discovering Genomics, Proteomics, and Bioinformatics,2003) Public access for teaching genomics, proteomics, and

  12. Incorporating Genomics and Bioinformatics across the Life Sciences Curriculum

    SciTech Connect (OSTI)

    Ditty, Jayna L.; Kvaal, Christopher A.; Goodner, Brad; Freyermuth, Sharyn K.; Bailey, Cheryl; Britton, Robert A.; Gordon, Stuart G.; Heinhorst, Sabine; Reed, Kelynne; Xu, Zhaohui; Sanders-Lorenz, Erin R.; Axen, Seth; Kim, Edwin; Johns, Mitrick; Scott, Kathleen; Kerfeld, Cheryl A.

    2011-08-01T23:59:59.000Z

    Undergraduate life sciences education needs an overhaul, as clearly described in the National Research Council of the National Academies publication BIO 2010: Transforming Undergraduate Education for Future Research Biologists. Among BIO 2010's top recommendations is the need to involve students in working with real data and tools that reflect the nature of life sciences research in the 21st century. Education research studies support the importance of utilizing primary literature, designing and implementing experiments, and analyzing results in the context of a bona fide scientific question in cultivating the analytical skills necessary to become a scientist. Incorporating these basic scientific methodologies in undergraduate education leads to increased undergraduate and post-graduate retention in the sciences. Toward this end, many undergraduate teaching organizations offer training and suggestions for faculty to update and improve their teaching approaches to help students learn as scientists, through design and discovery (e.g., Council of Undergraduate Research [www.cur.org] and Project Kaleidoscope [www.pkal.org]). With the advent of genome sequencing and bioinformatics, many scientists now formulate biological questions and interpret research results in the context of genomic information. Just as the use of bioinformatic tools and databases changed the way scientists investigate problems, it must change how scientists teach to create new opportunities for students to gain experiences reflecting the influence of genomics, proteomics, and bioinformatics on modern life sciences research. Educators have responded by incorporating bioinformatics into diverse life science curricula. While these published exercises in, and guidelines for, bioinformatics curricula are helpful and inspirational, faculty new to the area of bioinformatics inevitably need training in the theoretical underpinnings of the algorithms. Moreover, effectively integrating bioinformatics into courses or independent research projects requires infrastructure for organizing and assessing student work. Here, we present a new platform for faculty to keep current with the rapidly changing field of bioinformatics, the Integrated Microbial Genomes Annotation Collaboration Toolkit (IMG-ACT). It was developed by instructors from both research-intensive and predominately undergraduate institutions in collaboration with the Department of Energy-Joint Genome Institute (DOE-JGI) as a means to innovate and update undergraduate education and faculty development. The IMG-ACT program provides a cadre of tools, including access to a clearinghouse of genome sequences, bioinformatics databases, data storage, instructor course management, and student notebooks for organizing the results of their bioinformatic investigations. In the process, IMG-ACT makes it feasible to provide undergraduate research opportunities to a greater number and diversity of students, in contrast to the traditional mentor-to-student apprenticeship model for undergraduate research, which can be too expensive and time-consuming to provide for every undergraduate. The IMG-ACT serves as the hub for the network of faculty and students that use the system for microbial genome analysis. Open access of the IMG-ACT infrastructure to participating schools ensures that all types of higher education institutions can utilize it. With the infrastructure in place, faculty can focus their efforts on the pedagogy of bioinformatics, involvement of students in research, and use of this tool for their own research agenda. What the original faculty members of the IMG-ACT development team present here is an overview of how the IMG-ACT program has affected our development in terms of teaching and research with the hopes that it will inspire more faculty to get involved.

  13. Post-Genomics Nanotechnology Is Gaining Momentum: Nanoproteomics and Applications in Life Sciences

    E-Print Network [OSTI]

    Tan, Weihong

    Post-Genomics Nanotechnology Is Gaining Momentum: Nanoproteomics and Applications in Life Sciences of nanotechnology applications, including nanoporous structures, functionalized nanoparticles, quantum dots

  14. Applications of Genome-based Science in Shaping Citrus Industries of the World (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    SciTech Connect (OSTI)

    Gmitter Jr, Fred [University of Florida

    2012-03-21T23:59:59.000Z

    Fred Gmitter from the University of Florida on "Applications of Genome-based Science in Shaping the Future of the World's Citrus Industries" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  15. Applications of Genome-based Science in Shaping Citrus Industries of the World (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    ScienceCinema (OSTI)

    Gmitter Jr, Fred [University of Florida

    2013-01-15T23:59:59.000Z

    Fred Gmitter from the University of Florida on "Applications of Genome-based Science in Shaping the Future of the World's Citrus Industries" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  16. Los Alamos Science: The Human Genome Project. Number 20, 1992

    SciTech Connect (OSTI)

    Cooper, N G; Shea, N [eds.

    1992-01-01T23:59:59.000Z

    This article provides a broad overview of the Human Genome Project, with particular emphasis on work being done at Los Alamos. It tries to emphasize the scientific aspects of the project, compared to the more speculative information presented in the popular press. There is a brief introduction to modern genetics, including a review of classic work. There is a broad overview of the Genome Project, describing what the project is, what are some of its major five-year goals, what are major technological challenges ahead of the project, and what can the field of biology, as well as society expect to see as benefits from this project. Specific results on the efforts directed at mapping chromosomes 16 and 5 are discussed. A brief introduction to DNA libraries is presented, bearing in mind that Los Alamos has housed such libraries for many years prior to the Genome Project. Information on efforts to do applied computational work related to the project are discussed, as well as experimental efforts to do rapid DNA sequencing by means of single-molecule detection using applied spectroscopic methods. The article introduces the Los Alamos staff which are working on the Genome Project, and concludes with brief discussions on ethical, legal, and social implications of this work; a brief glimpse of genetics as it may be practiced in the next century; and a glossary of relevant terms.

  17. Entrepreneurial experiments in science policy: Analyzing the Human Genome Project

    E-Print Network [OSTI]

    Huang, Kenneth G.

    We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments ...

  18. Genome To Life Report | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 IndustrialIsadoreConnecticut Regions National Science2Gcreport Biological andGenome

  19. Current Genomics, 2004, 5, 299-308 1 1389-2029/04 $45.00+.00 2004 Bentham Science Publishers Ltd.

    E-Print Network [OSTI]

    Martin, Cristofre

    Current Genomics, 2004, 5, 299-308 1 1389-2029/04 $45.00+.00 ©2004 Bentham Science Publishers Ltd. Not Just a Fishing Trip ­ Environmental Genomics Using Zebrafish Louise E. Coverdale, David Lean and C. Cristofre Martin* Center for Advanced Research in Environmental Genomics, Department of Biology, University

  20. Current Genomics, 2002, 3, 000-000 1 1389-2029/02 $35.00+.00 2002 Bentham Science Publishers Ltd.

    E-Print Network [OSTI]

    Wendel, Jonathan F.

    Current Genomics, 2002, 3, 000-000 1 1389-2029/02 $35.00+.00 © 2002 Bentham Science Publishers Ltd. Non-Mendelian Phenomena in Allopolyploid Genome Evolution Bao Liu1 and Jonathan F. Wendel2,* 1. Recent evidence indicates that this genome doubling may be accompanied by a variety of non- Mendelian

  1. Standards in Genomic Science: An Open-Access Journal of the Genomic Standards Consortium (GSC8 Meeting)

    ScienceCinema (OSTI)

    Garrity, George

    2011-06-03T23:59:59.000Z

    George Garrity of Michigan State University talks about the GSC's open-access journal SIGS at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

  2. Computational methods and analyses in comparative genomics and epigenomics

    E-Print Network [OSTI]

    Peng, Qian

    2012-01-01T23:59:59.000Z

    promise of comparative genomics in mammals. Science, 286,homology relationships. Genomics, Dehal, P. and Boore, J.to plant comparative genomics. Genome Research, 13(5), 999

  3. Genomic Advances to Improve Biomass for Biofuels (LBNL Science at the Theater)

    ScienceCinema (OSTI)

    Rokhsar, Daniel

    2011-04-28T23:59:59.000Z

    Lawrence Berkeley National Lab bioscientist Daniel Rokhsar discusses genomic advances to improve biomass for biofuels. He presented his talk Feb. 11, 2008 in Berkeley, California as part of Berkeley Lab's community lecture series. Rokhsar works with the U.S. Department of Energy's Joint Genome Institute and Berkeley Lab's Genomics Division.

  4. Whitehead Policy Symposium. The Human Genome Project: Science, law, and social change in the 21st century

    SciTech Connect (OSTI)

    Nichols, E.K.

    2000-02-17T23:59:59.000Z

    Advances in the biomedical sciences, especially in human genomics, will dramatically influence law, medicine, public health, and many other sectors of our society in the decades ahead. The public already senses the revolutionary nature of genomic knowledge. In the US and Europe, we have seen widespread discussions about genetic discrimination in health insurance; privacy issues raised by the proliferation of DNA data banks; the challenge of interpreting new DNA diagnostic tests; changing definitions of what it means to be healthy; and the science and ethics of cloning animals and human beings. The primary goal of the Whitehead/ASLME Policy Symposium was to provide a bridge between the research community and professionals, who were just beginning to grasp the potential impact of new genetic technologies on their fields. The ''Human Genome Project: Science, Law, and Social Change in the 21st Century'' initially was designed as a forum for 300-500 physicians, lawyers, consumers, ethicists, and scientists to explore the impact of new genetic technologies and prepare for the challenges ahead.

  5. GIS: a web-based genomics information system for efficiently manipulating and accessing genome physical maps.

    E-Print Network [OSTI]

    Chen, Huaming

    2012-01-01T23:59:59.000Z

    ??Biological science has entered the genome era. Global genome integrative physical and genetic mapping promises to revolutionize modern genomics research. To facilitate manipulation and applications (more)

  6. First Annual U.S. Department of Energy Office of Science Joint Genome Institute User Meeting

    E-Print Network [OSTI]

    Various

    2006-01-01T23:59:59.000Z

    Genome Analysis of MTBE-Degrading Beta- Proteobacteriummethyl tert- butyl ether (MTBE). Strain PM1 can alsooften co-contaminants with MTBE in groundwater, including

  7. Personal Genomics, Personalized Medicine,

    E-Print Network [OSTI]

    Napp, Nils

    Personal Genomics, Personalized Medicine, & YOU Carrie Iwema, PhD, MLS 21st May 2012 AAAS/Science Translational Medicine panel discussion; MLA 2012 #12;Timeline: Human Genome Sequence HSLS, U.Pitt 1995 2014 2000 2003 2007 2007 2010 Human Genome Draft Sequence Complete Human Reference Genome Individual Human

  8. FUNCTIONAL GENOMICS Program of Study

    E-Print Network [OSTI]

    Thomas, Andrew

    FUNCTIONAL GENOMICS Program of Study Research Areas Students Applying Correspondence Graduate Genomics. Students receive training in the biological, physical and computational sciences through of primary institutional affiliation. The Functional Genomics program is administered through the Graduate

  9. First Annual U.S. Department of Energy Office of Science Joint Genome Institute User Meeting

    E-Print Network [OSTI]

    Various

    2006-01-01T23:59:59.000Z

    solvents tetrachloroethene (PCE) and trichloroethene (TCE),PCBs. The genome of the PCE-dechlorinating D. ethenogenesin D. ethenogenes grown on PCE or TCE by qPCR showed high

  10. GIS: a web-based genomics information system for efficiently manipulating and accessing genome physical maps

    E-Print Network [OSTI]

    Chen, Huaming

    2000-01-01T23:59:59.000Z

    Biological science has entered the genome era. Global genome integrative physical and genetic mapping promises to revolutionize modern genomics research. To facilitate manipulation and applications of the results from genomics research, many...

  11. Tissue sampling and standards for vertebrate genomics

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    and standards for vertebrate genomics. GigaScience 2012 1:8.transition to conservation genomics. TIG 2010, 26:177187.Siemens DH: Ecological genomicschanging perspectives on

  12. Computational genomics : mapping, comparison, and annotation of genomes

    E-Print Network [OSTI]

    Batzoglou, Serafim

    2000-01-01T23:59:59.000Z

    The field of genomics provides many challenges to computer scientists and mathematicians. The area of computational genomics has been expanding recently, and the timely application of computer science in this field is ...

  13. Translational Science Seminar The University of Illinois at Chicago (UIC) Center for Clinical and

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    Science department applies multidisciplinary approaches involving human genetics, functional genomics

  14. Outlook GENOME ANALYSIS Errors in genome annotation 0168-9525/99/$ see front matter 1999 Elsevier Science All rights reserved. PII: S0168-9525(99)01706-0132

    E-Print Network [OSTI]

    Elsevier Science All rights reserved. PII: S0168-9525(99)01706-0132 At the time that Watson and Crick

  15. Reference set of regulons in Desulfovibrionales inferred by comparative genomics approach

    E-Print Network [OSTI]

    Kazakov, A.E.

    2011-01-01T23:59:59.000Z

    inferred by comparative genomics approach 1 Lawrenceout large-scale comparative genomics analysis of regulatoryEnvironmental Research, Genomics:GTL Foundational Science

  16. Methods in comparative genomics: genome correspondence, gene identification and motif discovery

    E-Print Network [OSTI]

    Kellis, Manolis

    1 Methods in comparative genomics: genome correspondence, gene identification and motif discovery@mit.edu, nickp@genome.wi.mit.edu, bwb@genome.wi.mit.edu, bab@mit.edu, lander@wi.mit.edu (1) MIT/Whitehead Institute Center for Genome Research, 320 Charles St., Cambridge MA 02139 (2) MIT Computer Science

  17. Stories of Discovery & Innovation: From Human Genome to Materials...

    Office of Science (SC) Website

    Stories of Discovery & Innovation: From Human Genome to Materials "Genome" Energy Frontier Research Centers (EFRCs) EFRCs Home Centers Research Science Highlights News & Events...

  18. Genome Science/Technologies

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    student working with Armand Dichosa, Cliff Han and Krista Reitenga. She spends the bulk of her time on projects utilizing gel microdroplet technology. Armand Dichosa, PhD,...

  19. THE CAMPAIGN FOR UC SANTA CRUZ THE GENOMICS

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    THE CAMPAIGN FOR UC SANTA CRUZ THE GENOMICS INSTITUTE #12;OVERVIEW The UC Santa Cruz Genomics Institute provides the framework for the next great leap in the science of genomics. ensured it would genomic science and speed the benefits of discoveries that improve and save lives. Cancer, autoimmune

  20. E-Print Network 3.0 - affects genome stability Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Biology, Stanford University Collection: Biology and Medicine 2 The Environmental Genomics programme Science and implementation plan Summary: The Environmental Genomics...

  1. U.S. Department of Energy's Office of Science

    E-Print Network [OSTI]

    Science, Engineering, & Technology - Hydrogen Production, Storage, and Use - Genomics: GTL, including

  2. Genomic Aspects of Research Involving Polyploid Plants

    SciTech Connect (OSTI)

    Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

    2011-01-01T23:59:59.000Z

    Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

  3. Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group Centerfor systematics - is it relevant to modern science? Istanbul, Turkey 8 August, 2008 - or - What can genomics tell us about Vibrio species? Discovering natural groups in Vibrio #12;Comparative Microbial Genomics

  4. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work...

  5. Molluscan Evolutionary Genomics

    E-Print Network [OSTI]

    Simison, W. Brian

    2010-01-01T23:59:59.000Z

    59179 Molluscan Evolutionary Genomics W. Brian Simison andBoore Molluscan Evolutionary Genomics W. Brian Simison andL. Boore Evolutionary Genomics Department, DOE Joint Genome

  6. Human Genome Program Image Gallery (from genomics.energy.gov)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    This collection contains approximately 240 images from the genome programs of DOE's Office of Science. The images are divided into galleries related to biofuels research, systems biology, and basic genomics. Each image has a title, a basic citation, and a credit or source. Most of the images are original graphics created by the Genome Management Information System (GMIS). GMIS images are recognizable by their credit line. Permission to use these graphics is not needed, but please credit the U.S. Department of Energy Genome Programs and provide the website http://genomics.energy.gov. Other images were provided by third parties and not created by the U.S. Department of Energy. Users must contact the person listed in the credit line before using those images. The high-resolution images can be downloaded.

  7. A Taste of Algal Genomes from the Joint Genome Institute

    SciTech Connect (OSTI)

    Kuo, Alan; Grigoriev, Igor

    2012-06-17T23:59:59.000Z

    Algae play profound roles in aquatic food chains and the carbon cycle, can impose health and economic costs through toxic blooms, provide models for the study of symbiosis, photosynthesis, and eukaryotic evolution, and are candidate sources for bio-fuels; all of these research areas are part of the mission of DOE's Joint Genome Institute (JGI). To date JGI has sequenced, assembled, annotated, and released to the public the genomes of 18 species and strains of algae, sampling almost all of the major clades of photosynthetic eukaryotes. With more algal genomes currently undergoing analysis, JGI continues its commitment to driving forward basic and applied algal science. Among these ongoing projects are the pan-genome of the dominant coccolithophore Emiliania huxleyi, the interrelationships between the 4 genomes in the nucleomorph-containing Bigelowiella natans and Guillardia theta, and the search for symbiosis genes of lichens.

  8. Genome Engineering

    SciTech Connect (OSTI)

    Voytas, Dan [University of Minnesota

    2014-03-20T23:59:59.000Z

    Dan Voytas, University of Minnesota, at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif

  9. JIBS | Joint Institute for Biological Sciences | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    joint institute is located close to ORNL's Laboratory for Comparative and Functional Genomics, other biomolecular sciences research laboratories, and the Environmental Sciences...

  10. The comparative genomics of salinispora and the distribution and abundance of secondary metabolite genes in marine plankton

    E-Print Network [OSTI]

    Penn, Kevin Matthew

    2012-01-01T23:59:59.000Z

    rplB smpB Comparative genomics Gene gain Gene loss Totalbiology and comparative genomics. BMC Bioinformatics 10(1):Intersection of Evolution and Genomics. Science 300(5626):

  11. Genome Analyses and Supplement Data from the International Populus Genome Consortium (IPGC)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    International Populus Genome Consortium (IPGC)

    The sequencing of the first tree genome, that of Populus, was a project initiated by the Office of Biological and Environmental Research in DOEs Office of Science. The International Populus Genome Consortium (IPGC) was formed to help develop and guide post-sequence activities. The IPGC website, hosted at the Oak Ridge National Laboratory, provides draft sequence data as it is made available from DOE Joint Genome Institute, genome analyses for Populus, lists of related publications and resources, and the science plan. The data are available at http://www.ornl.gov/sci/ipgc/ssr_resource.htm.

  12. Translational genomics of Vegetable Crops Las Vegas, NV

    E-Print Network [OSTI]

    Douches, David S.

    Translational genomics of Vegetable Crops Las Vegas, NV July 21, 2005 David Francis and Allen Van Deynze At the recent ASHS meetings in Las Vegas, a workshop "Translational Genomics of Vegetable Crops interventions" (Minna and Gazdar, 1996). In applied plant science, "translational genomics" implies

  13. Current developments in genomics challenge the established framework of

    E-Print Network [OSTI]

    Church, George M.

    Current developments in genomics challenge the established framework of biomedical ethics because the empirical facts of the genomic science change too fast for the reflections of ethics to keep pace with for pragmatic moral guidance1 . Recent revelations about the human genome, such as the abundance of copy

  14. Mapping the Human Genome: UC SANTA CRUZUC SANTA CRUZ

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    Mapping the Human Genome: UC SANTA CRUZUC SANTA CRUZ University of California Santa Cruz Foundation" of the human genome under the direction of UCSC computer science professor David Haussler (right). Story world. Unlocking the mysteries of the human genome and applying this new knowledge to improve our health

  15. JGI Fungal Genomics Program

    E-Print Network [OSTI]

    Grigoriev, Igor V.

    2011-01-01T23:59:59.000Z

    View Supports functional genomics, user data deposition andJGI Fungal Genomics Program Igor V. Grigoriev 1 DOE Jointof California. JGI Fungal Genomics Program Contact: Igor

  16. Fungal Genomics Program

    E-Print Network [OSTI]

    Grigoriev, Igor

    2012-01-01T23:59:59.000Z

    strains Comparative genomics and transcriptomics of xyloseFungal Genomics Program Igor Grigoriev 1 * (complex communities Fungal Genomics Program Igor Grigoriev

  17. JGI Fungal Genomics Program

    E-Print Network [OSTI]

    Grigoriev, Igor V.

    2012-01-01T23:59:59.000Z

    JGI Fungal Genomics Program Igor V. Grigoriev 1 Lawrenceof California. JGI Fungal Genomics Program Contact: IgorJGI). Its key project, the Genomics Encyclopedia of Fungi,

  18. Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert Southwest RegionatSearchScheduled System Outages NERSC Scheduled Systemresearch Science

  19. Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassiveSubmitted for USMaterialstheterahertzonExplore by Subjectsupernova*Science

  20. *** CANCELED *** SCIENCE ON SATURDAY- "Finding a Needle in A...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cure Cancer" Professor Olga G. Troyanskaya Lewis-Sigler Institute for Integrative Genomics & Department of Computer Science, Princeton University Science on Saturday is a...

  1. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

  2. E-Print Network 3.0 - aspergillus niger genome-wide Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Marine Benthic Ecology and Evolution, Collection: Biology and Medicine ; Environmental Sciences and Ecology 14 Genome sequencing and analysis of the versatile cell...

  3. INTRODUCTION TO GENOMIC MEDICINE

    E-Print Network [OSTI]

    INTRODUCTION TO GENOMIC MEDICINE Genomics play a role in 21st century research and clinical related to genomic medicine. Tentative Schedule: WHEN: WHERE: WHO CAN ATTEND? INTRODUCTION January 31 Implications of Genomics in Clinical Medicine February 7 Molecular Biology/Genetics Refresher - 1 February 14

  4. Discovery of functional elements in 12 Drosophila genomes using evolutionary

    E-Print Network [OSTI]

    Bartel, David

    ,6 , Joseph W. Carlson7 , Madeline A. Crosby8 , Matthew D. Rasmussen2 , Sushmita Roy9 , Ameya N. Deoras2 , J, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. 6 Institute of Computer Science, University

  5. Discovery of functional elements in 12 Drosophila genomes using evolutionary

    E-Print Network [OSTI]

    Kellis, Manolis

    Parts5,6 , Joseph W. Carlson7 , Madeline A. Crosby8 , Matthew D. Rasmussen2 , Sushmita Roy9 , Ameya N, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. 6 Institute of Computer Science, Un

  6. A GSC Global Genome Census (GSC8 Meeting)

    ScienceCinema (OSTI)

    Kyrpides, Nikos [DOE JGI

    2011-04-29T23:59:59.000Z

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding "Research Coordination Network" from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Nikos Kyrpides of the DOE Joint Genome Institute discusses the notion of a global genome census at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

  7. Assembly free comparative genomics of short-read sequence data discovers the needles in the haystack

    E-Print Network [OSTI]

    Assembly free comparative genomics of short-read sequence data discovers the needles of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA Abstract Most comparative genomic analyses an assembly free analysis of SRS data that discovers sequence variants among focal genomes by tabulating

  8. Brian Giebel Subject: FW: Faculty positions in Plant Genomics and Pathway Engineering at the JGI

    E-Print Network [OSTI]

    Borenstein, Elhanan

    1 Brian Giebel Subject: FW: Faculty positions in Plant Genomics and Pathway Engineering at the JGI: Faculty positions in Plant Genomics and Pathway Engineering at the JGI To: Jay Shendure coming out in Science targeted at recruiting individuals in plant genomics and pathway engineering

  9. Mutation Research 504 (2002) 91100 Bystander effects in radiation-induced genomic instability

    E-Print Network [OSTI]

    Mutation Research 504 (2002) 91­100 Bystander effects in radiation-induced genomic instability recombination and other phenotypes associated with genomic instability. © 2002 Elsevier Science B.V. All rights reserved. Keywords: Bystander effects; Genomic instability; Ionizing radiation 1. Introduction Exposure

  10. JGI Fungal Genomics Program

    SciTech Connect (OSTI)

    Grigoriev, Igor V.

    2011-03-14T23:59:59.000Z

    Genomes of energy and environment fungi are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 50 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such 'parts' suggested by comparative genomics and functional analysis in these areas are presented here

  11. Genomic Encyclopedia of Fungi

    SciTech Connect (OSTI)

    Grigoriev, Igor

    2012-08-10T23:59:59.000Z

    Genomes of fungi relevant to energy and environment are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 150 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such parts suggested by comparative genomics and functional analysis in these areas are presented here.

  12. Genome Biology 2004, 5:R92 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    Zitzler, Eckart

    Federal Institute of Technology (ETH), Zurich. Colab, ETH, Zurich 8092, Switzerland. Seminar for Statistics, ETH, Zurich 8092, Switzerland. §Institute for Plant Sciences and Functional Genomics Center Zurich, ETH, Zurich 8092, Switzerland. ¶Computer Engineering and Networks Laboratory, ETH, Zurich 8092

  13. Genomics and the human genome project: implications for psychiatry

    E-Print Network [OSTI]

    Kelsoe, J R

    2004-01-01T23:59:59.000Z

    and psychosis: a convergent functional genomics approach.Physiology & Genomics, 4, 8391. O LIPHANT , A. , B ARKER ,2004), 16(4), 294300 Genomics and the Human Genome Project:

  14. Biology & Biomedical Sciences ACADEMIC PROGRAM

    E-Print Network [OSTI]

    Stormo, Gary

    Biology & Biomedical Sciences ACADEMIC PROGRAM GUIDELINES Programs in Cell & Molecular Biology Developmental, Regenerative and Stem Cell Biology Molecular Cell Biology Molecular Genetics & Genomics Molecular Microbiology & Microbial Pathogenesis #12;PAGE 2 GUIDELINES TO THE PROGRAMS IN CELL AND MOLECULAR BIOLOGY

  15. Defining Genome Project Standards in a New Era of Sequencing (GSC8 Meeting)

    ScienceCinema (OSTI)

    Chain, Patrick [DOE JGI

    2011-04-28T23:59:59.000Z

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding "Research Coordination Network" from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego.

  16. Fungal Genomics Program

    SciTech Connect (OSTI)

    Grigoriev, Igor

    2012-03-12T23:59:59.000Z

    The JGI Fungal Genomics Program aims to scale up sequencing and analysis of fungal genomes to explore the diversity of fungi important for energy and the environment, and to promote functional studies on a system level. Combining new sequencing technologies and comparative genomics tools, JGI is now leading the world in fungal genome sequencing and analysis. Over 120 sequenced fungal genomes with analytical tools are available via MycoCosm (www.jgi.doe.gov/fungi), a web-portal for fungal biologists. Our model of interacting with user communities, unique among other sequencing centers, helps organize these communities, improves genome annotation and analysis work, and facilitates new larger-scale genomic projects. This resulted in 20 high-profile papers published in 2011 alone and contributing to the Genomics Encyclopedia of Fungi, which targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts). Our next grand challenges include larger scale exploration of fungal diversity (1000 fungal genomes), developing molecular tools for DOE-relevant model organisms, and analysis of complex systems and metagenomes.

  17. Webinar: Materials Genome Initative

    Broader source: Energy.gov [DOE]

    Audio recording and text version of the Fuel Cell Technologies Office webinar titled "Materials Genome Initiative," originally presented on December 2, 2014.

  18. Life sciences and environmental sciences

    SciTech Connect (OSTI)

    Not Available

    1992-02-01T23:59:59.000Z

    The DOE laboratories play a unique role in bringing multidisciplinary talents -- in biology, physics, chemistry, computer sciences, and engineering -- to bear on major problems in the life and environmental sciences. Specifically, the laboratories utilize these talents to fulfill OHER`s mission of exploring and mitigating the health and environmental effects of energy use, and of developing health and medical applications of nuclear energy-related phenomena. At Lawrence Berkeley Laboratory (LBL) support of this mission is evident across the spectrum of OHER-sponsored research, especially in the broad areas of genomics, structural biology, basic cell and molecular biology, carcinogenesis, energy and environment, applications to biotechnology, and molecular, nuclear and radiation medicine. These research areas are briefly described.

  19. Life sciences and environmental sciences

    SciTech Connect (OSTI)

    Not Available

    1992-02-01T23:59:59.000Z

    The DOE laboratories play a unique role in bringing multidisciplinary talents -- in biology, physics, chemistry, computer sciences, and engineering -- to bear on major problems in the life and environmental sciences. Specifically, the laboratories utilize these talents to fulfill OHER's mission of exploring and mitigating the health and environmental effects of energy use, and of developing health and medical applications of nuclear energy-related phenomena. At Lawrence Berkeley Laboratory (LBL) support of this mission is evident across the spectrum of OHER-sponsored research, especially in the broad areas of genomics, structural biology, basic cell and molecular biology, carcinogenesis, energy and environment, applications to biotechnology, and molecular, nuclear and radiation medicine. These research areas are briefly described.

  20. Enhancer Identification through Comparative Genomics

    E-Print Network [OSTI]

    Visel, Axel; Bristow, James; Pennacchio, Len A.

    2006-01-01T23:59:59.000Z

    through Comparative Genomics Axel Visel, James Bristow andWalnut Creek, CA 94598 USA. Genomics Division, MS 84-171,Len A. Pennacchio, Genomics Division, One Cyclotron Road, MS

  1. The Future of Microbial Genomics

    SciTech Connect (OSTI)

    Kyrpides, Nikos [Genome Biology group at the DOE Joint Genome Institute

    2010-06-02T23:59:59.000Z

    Nikos Kyrpides, head of the Genome Biology group at the DOE Joint Genome Institute discusses current challenges in the field of microbial genomics on June 2, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

  2. Genomic analysis of mouse tumorigenesis

    E-Print Network [OSTI]

    Tam, Mandy Chi-Mun

    2006-01-01T23:59:59.000Z

    The availability of the human and mouse genome sequences has spurred a growing interest in analyzing mouse models of human cancer using genomic techniques. Comparative genomic studies on mouse and human tumors can be ...

  3. Genomic Analysis of Burkholderia And Rhodococcus equi Bacteriophages

    E-Print Network [OSTI]

    Orchard II, Robert C.

    2011-08-04T23:59:59.000Z

    bacteriophages and pyrosequenced using 454 LifeSciences Technology. These phages are mosaic and sequencing traditional plasmid libraries were sufficient to deconvolute the 454 data. Also reported is the complete genomic sequencing of BcepNY3, a Burkholderia... cenocepacia bacteriophage via a Whole Genome Shotgun Approach. BcepNY3?s 47,382 bp genome was found to encode 70 proteins and 1 tRNA. It was determined that BcepNY3 is part of the previously described Bcep781 family of phages (26). Surprisingly...

  4. National Commission on Forensic Science (NCFS) and

    E-Print Network [OSTI]

    National Commission on Forensic Science (NCFS) and Organization of Scientific Area Committees (OSAC and Technology NIST Fellow & Special Assistant to the Director for Forensic Science Vice-Chair, National Commission on Forensic Science GenomeID Forum Greenville, NC September 10, 2014 #12;Material Measurement

  5. Automated Microbial Genome Annotation

    SciTech Connect (OSTI)

    Land, Miriam [DOE Joint Genome Institute at Oak Ridge National Laboratory

    2009-05-29T23:59:59.000Z

    Miriam Land of the DOE Joint Genome Institute at Oak Ridge National Laboratory gives a talk on the current state and future challenges of moving toward automated microbial genome annotation at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

  6. Evolutionary Genomics of Salmonella enterica Subspecies

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    M. 2013. Evolutionary genomics of Salmonella entericaEvolutionary Genomics of Salmonella enterica Subspecies

  7. NREL Support for a Functional Genomics Approach to Investigate Regulation of Phenolic Glycoside: Cooperative Research and Development Final Report, CRADA number CRD-07-00218

    SciTech Connect (OSTI)

    Davis, M.

    2010-07-01T23:59:59.000Z

    NREL and MTU collaborated on a proposal 'A Functional Genomics Approach to Investigate Regulation of Phenolic Glycoside Metabolism in Populus' funded by the National Science Foundation.

  8. Institute for Plant Genomics and Biotechnology GENOMICS AND BIOTECHNOLOGY

    E-Print Network [OSTI]

    Institute for Plant Genomics and Biotechnology GENOMICS AND BIOTECHNOLOGY A multidisciplinary organization, the Institute for Plant Genomics and Biotechnology is a composed of faculty members representing projects at the Institute for Plant Genomics and Biotechnology include the development of transgenic plants

  9. Comparative and Functional Genomics Comp Funct Genom 2003; 4: 239245.

    E-Print Network [OSTI]

    Wurtele, Eve Syrkin

    Comparative and Functional Genomics Comp Funct Genom 2003; 4: 239­245. Published online 1 April://www.botany.iastate.edu/mash/metnetex/metabolicnetex.html) is pub- licly available software in development for analysis of genome-wide RNA, protein and metabolite in the post-genome era is to understand how interactions among molecules in a cell determine its form

  10. Update on Genomic Studies of Algae Paths toward Algal Genomics

    E-Print Network [OSTI]

    Update on Genomic Studies of Algae Paths toward Algal Genomics Arthur R. Grossman* The Carnegie of genomic information that is being used to help researchers understand the gene content of organisms, how the expression of genes. In this introductory manuscript, I discuss select algae and how genomics is impacting

  11. Comparative and Functional Genomics Comp Funct Genom 2003; 4: 3136.

    E-Print Network [OSTI]

    Allen, John F.

    Comparative and Functional Genomics Comp Funct Genom 2003; 4: 31­36. Published online in Wiley and mitochondria contain genomes John F. Allen* Plant Biochemistry, Center for Chemistry and Chemical Engineering that the nucleotide sequences of mitochondrial and chloroplast genomes would provide the answer has proved unfounded

  12. Eukaryotic Genomics Data from the DOE Joint Genome Institute (JGI)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    From the JGI webportal users can choose Eukaryotic genomes from a photo list, access the JGI FTP directories to download data files, use the Tree of Life navigation tool, or choose a genome and go directly to a website specific to that one genome. The individual sites include direct access to download sequence files, BLAST, search, view and navigate the genomic annotations.

  13. Comparative genomics of the core and accessory genomes of 48 Sinorhizobium strains comprising five genospecies

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    annotation and comparative genomics. Database (Oxford) 2009,et al. : Comparative genomics of the core and accessoryComparative genomics of the core and accessory genomes of 48

  14. Granularity of genomics data in genome visualisation

    E-Print Network [OSTI]

    Jakubowska, J.; Hunt, E.

    Jakubowska,J. Hunt,E. Chalmers,M.J. DCS Technical Report Series pp 10 Dept of Computing Science, University of Glasgow

  15. Human Genome Program

    SciTech Connect (OSTI)

    Not Available

    1993-01-01T23:59:59.000Z

    The DOE Human Genome program has grown tremendously, as shown by the marked increase in the number of genome-funded projects since the last workshop held in 1991. The abstracts in this book describe the genome research of DOE-funded grantees and contractors and invited guests, and all projects are represented at the workshop by posters. The 3-day meeting includes plenary sessions on ethical, legal, and social issues pertaining to the availability of genetic data; sequencing techniques, informatics support; and chromosome and cDNA mapping and sequencing.

  16. The Center for integrative genomics

    E-Print Network [OSTI]

    Kaessmann, Henrik

    The Center for integrative genomics Report 2005­2006 #12;Presentation Director's message 4 Scientific advisory committee 6 Organigram of the CIG 7 research The structure and function of genomes and their evolution alexandrereymond ­ Genome structure and expression 10 henrikKaessmann ­ Evolutionary genomics 12

  17. Genomic Science | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 IndustrialIsadore Perlman,Bios High EnergyEliane SJulyFrequently Asked

  18. Franois Pompanon and Aurlie Bonin (eds.), Data Production and Analysis in Population Genomics: Methods and Protocols, Methods in Molecular Biology, vol. 888, DOI 10.1007/978-1-61779-870-2_17, Springer Science+Business Media New York 2012

    E-Print Network [OSTI]

    correlate allelic frequencies and environmental variables such as precipitation, temperature, or sun, temperature, sun radia- tion, etc.) (4, 5). In this case, the geographic coordinates (spatial variables Variables in the Context of Allele Distribution Models: Detecting Signatures of Selection in the Genome

  19. E-Print Network 3.0 - accelerated genome evolution Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1 2006, UCSC Center for Biomolecular Science & Engineering--Page 1 of 3 COMPARATIVE GENOMICS AT UCSC Summary: of evolution. DISCOVERIES AT UCSC The completion of the first three...

  20. Genomic library construction

    DOE Patents [OSTI]

    Church, George M. (Brookline, MA); Zhang, Kun (San Diego, CA)

    2011-07-26T23:59:59.000Z

    Compositions and methods for amplifying nucleic acid sequences from a single cell are provided. Compositions and methods for constructing a genomic library from a single cell are also provided.

  1. Human Genome Education Program

    SciTech Connect (OSTI)

    Richard Myers; Lane Conn

    2000-05-01T23:59:59.000Z

    The funds from the DOE Human Genome Program, for the project period 2/1/96 through 1/31/98, have provided major support for the curriculum development and field testing efforts for two high school level instructional units: Unit 1, ''Exploring Genetic Conditions: Genes, Culture and Choices''; and Unit 2, ''DNA Snapshots: Peaking at Your DNA''. In the original proposal, they requested DOE support for the partial salary and benefits of a Field Test Coordinator position to: (1) complete the field testing and revision of two high school curriculum units, and (2) initiate the education of teachers using these units. During the project period of this two-year DOE grant, a part-time Field-Test Coordinator was hired (Ms. Geraldine Horsma) and significant progress has been made in both of the original proposal objectives. Field testing for Unit 1 has occurred in over 12 schools (local and non-local sites with diverse student populations). Field testing for Unit 2 has occurred in over 15 schools (local and non-local sites) and will continue in 12-15 schools during the 96-97 school year. For both curricula, field-test sites and site teachers were selected for their interest in genetics education and in hands-on science education. Many of the site teachers had no previous experience with HGEP or the unit under development. Both of these first-year biology curriculum units, which contain genetics, biotechnology, societal, ethical and cultural issues related to HGP, are being implemented in many local and non-local schools (SF Bay Area, Southern California, Nebraska, Hawaii, and Texas) and in programs for teachers. These units will reach over 10,000 students in the SF Bay Area and continues to receive support from local corporate and private philanthropic organizations. Although HGEP unit development is nearing completion for both units, data is still being gathered and analyzed on unit effectiveness and student learning. The final field testing result from this analysis will contribute to the final revisions of each unit during the second-year of this grant.

  2. Genomics, Gene Expression and Other Studies in Soybean Rust

    E-Print Network [OSTI]

    Posada-Buitrago, Martha Lucia

    2005-01-01T23:59:59.000Z

    Joint Genome Institute Genomics, Gene Expression and otherRust Martha Luca Posada-Buitrago Ph.D Genomics DivisionEvolutionary Genomics DOE- Joint Genome Institute Lawrence

  3. SCIENCE CHINA Technological Sciences

    E-Print Network [OSTI]

    Wang, Zhong L.

    SCIENCE CHINA Technological Sciences © Science China Press and Springer-Verlag Berlin Heidelberg and Nanosystems, Chinese Academy of Sciences, Beijing 100083, China; 2 Institute of Theoretical Physics, Lanzhou University, Lanzhou 730000, China; 3 School of Material Science and Engineering, Georgia Institute

  4. Bioinformatics and Genomics Degree Requirements Booklet

    E-Print Network [OSTI]

    dePamphilis, Claude

    Bioinformatics and Genomics Degree Requirements Booklet Fall 2010 #12;Contents Course Requirements Bioinformatics and Genomics Curriculum -------------------------------------------------------8 General #12;Bioinformatics and Genomics Option (BG

  5. Fueling the Future with Fungal Genomics

    E-Print Network [OSTI]

    Grigoriev, Igor V.

    2011-01-01T23:59:59.000Z

    JW. 2010. China's fungal genomics initiative: a whitepaper.and Saccharomycotina. BMC Genomics. 8, 325. Bailly J,Harnessing ectomycorrhizal genomics for ecological insights.

  6. VISTA - computational tools for comparative genomics

    E-Print Network [OSTI]

    Frazer, Kelly A.; Pachter, Lior; Poliakov, Alexander; Rubin, Edward M.; Dubchak, Inna

    2004-01-01T23:59:59.000Z

    tools for comparative genomics Kelly A. Frazer 1 , LiorBerkeley, CA, 94720 Genomics Division, Lawrence Berkeleymultiple comparative genomics tools and provides users with

  7. Department of Energy funds genomic research By Paula Hartman Cohen

    E-Print Network [OSTI]

    Lovley, Derek

    Department of Energy funds genomic research By Paula Hartman Cohen News Office staff A research.S. Department of Energy (DOE) to determine whether the new field of ge- nomic science can be applied to clean DNA. "It's now our job to determine what all this genetic informa- tion can tell us about why

  8. BER Science Network Requirements

    SciTech Connect (OSTI)

    Dart, Eli; Tierney, Brian

    2010-11-01T23:59:59.000Z

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the US Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In April 2010 ESnet and the Office of Biological and Environmental Research, of the DOE Office of Science, organized a workshop to characterize the networking requirements of the science programs funded by BER. The requirements identified at the workshop are summarized and described in more detail in the case studies and the Findings section. A number of common themes emerged from the case studies and workshop discussions. One is that BER science, like many other disciplines, is becoming more and more distributed and collaborative in nature. Another common theme is that data set sizes are exploding. Climate Science in particular is on the verge of needing to manage exabytes of data, and Genomics is on the verge of a huge paradigm shift in the number of sites with sequencers and the amount of sequencer data being generated.

  9. Microbial Genomics Data from the DOE Joint Genome Institute (JGI)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    As of March 2008, The Joint Genome Institute has released 296 Prokaryotic microbial sites, with 216 in finished status.

  10. Mammalian comparative genomics and epigenomics

    E-Print Network [OSTI]

    Mikkelsen, Tarjei Sigurd, 1978-

    2009-01-01T23:59:59.000Z

    The human genome sequence can be thought of as an instruction manual for our species, written and rewritten over more than a billion of years of evolution. Taking a complete inventory of our genome, dissecting its genes ...

  11. Computer Science Computer Science?

    E-Print Network [OSTI]

    Eustice, Ryan

    Michigan Autonomous Aerial Vehicles, UM::Autonomy, U-M Programming, U-M Solar Car, Hybrid RacingComputer Science @ Michigan Life as a CS Student What is Computer Science? Computer science is shaping the future. A degree in computer science can help shape yours. Michigan CS students have

  12. Clinical Microfluidics for Neutrophil Genomics and Proteomics...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Clinical Microfluidics for Neutrophil Genomics and Proteomics. Clinical Microfluidics for Neutrophil Genomics and Proteomics. Abstract: Neutrophils play critical roles in...

  13. DOI: 10.1126/science.1241459 , 357 (2013);342Science

    E-Print Network [OSTI]

    Church, George M.

    DOI: 10.1126/science.1241459 , 357 (2013);342Science et al.Marc J. Lajoie Genomically Recoded.html#related found at: can berelated to this articleA list of selected additional articles on the Science Web sites articles hosted by HighWire Press; see:cited byThis article has been registered trademark of AAAS. is aScience

  14. SHORT REVIEW Butterfly genomics eclosing

    E-Print Network [OSTI]

    Beldade, Patrícia

    SHORT REVIEW Butterfly genomics eclosing P Beldade1 , WO McMillan2 and A Papanicolaou3 1 Section to an explosion of genomic data and the emergence of new research avenues. Evolutionary and ecological functional genomics, with its focus on the genes that affect ecological success and adaptation in natural populations

  15. International milk genomics consortium

    E-Print Network [OSTI]

    Rocke, David M.

    University, Wooster, OH 44691, USA c University of Idaho, Moscow, ID 83844, USA d University of Colorado. The general goals of the Milk Genomics Consortium are to link the scientific community through milk and geno value of milk's components is known (German, Dillard, & Ward, 2002). The scientific challenge, therefore

  16. Coral Reef Genomics: Developing tools for functional genomics of coral symbiosis

    E-Print Network [OSTI]

    Schwarz, Jodi; Brokstein, Peter; Manohar, Chitra; Coffroth, Mary Alice; Szmant, Alina; Medina, Monica

    2008-01-01T23:59:59.000Z

    Coral Reef Genomics: Developing toolsfor functional genomics of coral symbiosis Jodi SCHWARZ 1 ,symbiosis functional genomics cDNA microarray ABSTRACT

  17. Navigating protected genomics data with UCSC Genome Browser in a Box.

    E-Print Network [OSTI]

    2014-01-01T23:59:59.000Z

    H. et al. (2013) Integrative Genomics Viewer (IGV):High-performance genomics data visualization andbrowsers for comparative genomics. Bioinformatics. In press.

  18. SCIENCE CHINA Technological Sciences

    E-Print Network [OSTI]

    Ahmad, Sajjad

    SCIENCE CHINA Technological Sciences © Science China Press and Springer-Verlag Berlin Heidelberg HU HongChang, TIAN FuQiang* & HU HePing Department of Hydraulic Engineering, State Key Laboratory as a key soil physical parameter and has been widely used to predict soil hydraulic and other related

  19. SCIENCE CHINA Technological Sciences

    E-Print Network [OSTI]

    Simons, Jack

    SCIENCE CHINA Technological Sciences © Science China Press and Springer-Verlag Berlin Heidelberg. Density-functional-theory formulation of classical and quantum Hooke's law. Sci China Tech Sci, 2014, 57- sider an equilibrium lattice without strain (=0), but elec- #12;Hu H, et al. Sci China Tech Sci April

  20. Salt Stress in Desulfovibrio vulgaris Hildenborough: An integrated genomics approach

    E-Print Network [OSTI]

    Mukhopadhyay, Aindrila

    2010-01-01T23:59:59.000Z

    2002. Integrating cancer genomics and proteomics in theWeb site for comparative genomics. Genome Res 15:1015-22.Hildenborough: An integrated genomics approach. Aindrila

  1. acanthamoeba castellanii genome: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Medicine Websites Summary: Prokaryotic Genomes Eurkaryotic Genomes Chapter 6. Genomics and Gene Identification Weigang Qiu Weigang Qiu Chapter 6. Genomics and Gene...

  2. aeromonas caviae genomic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Medicine Websites Summary: Prokaryotic Genomes Eurkaryotic Genomes Chapter 6. Genomics and Gene Identification Weigang Qiu Weigang Qiu Chapter 6. Genomics and Gene...

  3. Population genomics: Whole-genome analysis of polymorphism and divergence in Drosophila simulans

    E-Print Network [OSTI]

    2007-01-01T23:59:59.000Z

    PLoS BIOLOGY Population Genomics: Whole-Genome Analysis ofwww.plosbiology.org Population Genomics of D. simulans Table11 | e310 Population Genomics of D. simulans Table S15. GO

  4. POSTDOCTORAL POSITION IN BIOINFORMATICS AND EVOLUTIONARY GENOMICS: Next generation sequencing and analysis of complex polyploid genomes

    E-Print Network [OSTI]

    Rennes, Université de

    POSTDOCTORAL POSITION IN BIOINFORMATICS AND EVOLUTIONARY GENOMICS: Next generation sequencing and analysis of complex polyploid genomes The research group Genome Evolution and Speciation (Team) to work on the analysis of genome and transcriptome sequence data (generated using 454 Roche

  5. Biological Production of Hydrogen DOE Office of Science,

    E-Print Network [OSTI]

    .Houghton@science.doe.gov #12;Biology transforms energy in a series ofBiology transforms energy in a series University Artificial Chromosome: Minimum Genome Oligo Assembly Microalgae production facility of Cyanotech

  6. Ecology and Evolutionary Biology The Wiess School of Natural Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    Ecology and Evolutionary Biology The Wiess School of Natural Sciences Chair Evan Siemann Professors of Ecology and Evolutionary Biologyoffersabroadrangeofcoursesinthebiosciences:animalbehavior,animal biology, bioinformatics, conservation biology, diseases, ecology, evolutionary biology, field ecology, genetics, genomics

  7. Original article Neisseria Base: a comparative genomics

    E-Print Network [OSTI]

    Jordan, King

    Original article Neisseria Base: a comparative genomics database for Neisseria meningitidis Lee S, septicemia and in some cases pneumonia. Genomic studies hold great promise for N. meningitidis research genomics database and genome browser that houses and displays publicly available N. meningitidis genomes

  8. A Novel Approach for Comparative Genomics

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    A Novel Approach for Comparative Genomics & Annotation Transfer Alban MANCHERON Raluca URICARU Eric is genome comparison good for?" Genome comparison is crucial for genome annotation, regulatory motifs identification, and vaccine design aims at finding genomic regions either specific to or in one

  9. Explore Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Explore Science Explore Explore these Topics Activities Videos Cool Links Favorite Q&A invisible utility element Science is thinking in an organized way about things...

  10. Detection Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Chemistry for Measurement and Detection Science Chemistry for Measurement and Detection Science Project Description Chemistry used in measurement and detection science plays a...

  11. DOE Joint Genome Institute 2008 Progress Report

    SciTech Connect (OSTI)

    Gilbert, David

    2009-03-12T23:59:59.000Z

    While initially a virtual institute, the driving force behind the creation of the DOE Joint Genome Institute in Walnut Creek, California in the Fall of 1999 was the Department of Energy's commitment to sequencing the human genome. With the publication in 2004 of a trio of manuscripts describing the finished 'DOE Human Chromosomes', the Institute successfully completed its human genome mission. In the time between the creation of the Department of Energy Joint Genome Institute (DOE JGI) and completion of the Human Genome Project, sequencing and its role in biology spread to fields extending far beyond what could be imagined when the Human Genome Project first began. Accordingly, the targets of the DOE JGI's sequencing activities changed, moving from a single human genome to the genomes of large numbers of microbes, plants, and other organisms, and the community of users of DOE JGI data similarly expanded and diversified. Transitioning into operating as a user facility, the DOE JGI modeled itself after other DOE user facilities, such as synchrotron light sources and supercomputer facilities, empowering the science of large numbers of investigators working in areas of relevance to energy and the environment. The JGI's approach to being a user facility is based on the concept that by focusing state-of-the-art sequencing and analysis capabilities on the best peer-reviewed ideas drawn from a broad community of scientists, the DOE JGI will effectively encourage creative approaches to DOE mission areas and produce important science. This clearly has occurred, only partially reflected in the fact that the DOE JGI has played a major role in more than 45 papers published in just the past three years alone in Nature and Science. The involvement of a large and engaged community of users working on important problems has helped maximize the impact of JGI science. A seismic technological change is presently underway at the JGI. The Sanger capillary-based sequencing process that dominated how sequencing was done in the last decade is being replaced by a variety of new processes and sequencing instruments. The JGI, with an increasing number of next-generation sequencers, whose throughput is 100- to 1,000-fold greater than the Sanger capillary-based sequencers, is increasingly focused in new directions on projects of scale and complexity not previously attempted. These new directions for the JGI come, in part, from the 2008 National Research Council report on the goals of the National Plant Genome Initiative as well as the 2007 National Research Council report on the New Science of Metagenomics. Both reports outline a crucial need for systematic large-scale surveys of the plant and microbial components of the biosphere as well as an increasing need for large-scale analysis capabilities to meet the challenge of converting sequence data into knowledge. The JGI is extensively discussed in both reports as vital to progress in these fields of major national interest. JGI's future plan for plants and microbes includes a systematic approach for investigation of these organisms at a scale requiring the special capabilities of the JGI to generate, manage, and analyze the datasets. JGI will generate and provide not only community access to these plant and microbial datasets, but also the tools for analyzing them. These activities will produce essential knowledge that will be needed if we are to be able to respond to the world's energy and environmental challenges. As the JGI Plant and Microbial programs advance, the JGI as a user facility is also evolving. The Institute has been highly successful in bending its technical and analytical skills to help users solve large complex problems of major importance, and that effort will continue unabated. The JGI will increasingly move from a central focus on 'one-off' user projects coming from small user communities to much larger scale projects driven by systematic and problem-focused approaches to selection of sequencing targets. Entire communities of scientists working in a particular field, such as feeds

  12. Evolutionary Genomics of Prokaryotic Viruses.

    E-Print Network [OSTI]

    Krupovic, Mart

    2010-01-01T23:59:59.000Z

    ??Evolutionary history of biological entities is recorded within their nucleic acid sequences and can (sometimes) be deciphered by thorough genomic analysis. In this study we (more)

  13. Computational genomics on the grid.

    E-Print Network [OSTI]

    Chen, Chunxi.

    2008-01-01T23:59:59.000Z

    ??The post-genomic era is characterized by large amount of data available from sequencing projects. The large size of biological datasets, inherent complexity of biological problems (more)

  14. Comparative genomics of arabidopsis thaliana.

    E-Print Network [OSTI]

    Hu, Tina T.

    2009-01-01T23:59:59.000Z

    ??The highly sel?ng Arabidopsis thaliana differs from its closest relative, the obligate outcrosser A. lyrata, both in genome size and organization. During approximately 5 million (more)

  15. 131Cognitive Science COGNITIVE SCIENCE

    E-Print Network [OSTI]

    Marsh, David

    131Cognitive Science COGNITIVE SCIENCE PROFESSOR ELMES* MAJOR A major in cognitive science leading courses: Cognitive Science 110, 395, 403, 473; Computer Science 111, 211; Philosophy 106, 313; Psychology Science: Com- puter Science 295 (LISP, PROLOG or C), 313, 315; Psychology 207 b. Philosophical Foundations

  16. The human genome project

    SciTech Connect (OSTI)

    Bell, G.I.

    1991-06-01T23:59:59.000Z

    The Human Genome Project will obtain high-resolution genetic and physical maps of each human chromosome and, somewhat later, of the complete nucleotide sequence of the deoxyribonucleic acid (DNA) in a human cell. The talk will begin with an extended introduction to explain the Project to nonbiologists and to show that map construction and sequence determination require extensive computation in order to determine the correct order of the mapped entities and to provide estimates of uncertainty. Computational analysis of the sequence data will become an increasingly important part of the project, and some computational challenges are described. 5 refs.

  17. Genomics Division Home

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genomefor Genomics DanPIs Mark

  18. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals.Genomefor Genomics DanPIs

  19. Integrative Genomics Building

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFunInfrared Land SurfaceVirus-Infected MacaquesIntegration ofIntegrative Genomics

  20. Yeast Genomic Library Genomic DNA Sau3AI partial digestion

    E-Print Network [OSTI]

    Odorizzi, Greg

    Yeast Genomic Library Concept: Genomic DNA Sau3AI partial digestion Vector DNA BamHI full digestion partial Ligate and transform above products Vector Information: use centromeric plasmid to avoid of the mcs Preparing Vector: 1) digest 3-4ug of library vector with BamHI for 2-4hrs in a total volume of 20

  1. Trichoderma: the genomics of opportunistic success

    E-Print Network [OSTI]

    Druzhinina, Irina S.

    2011-01-01T23:59:59.000Z

    of a fungal prey. BMC Genomics 10, 567 (2009). This studythe TrichoEST functional genomics approach. Curr. Genet. 51,in Hypocrea jecorina. BMC Genomics. 9, 430 (2008) Mukherjee,

  2. Evolutionary Genomics of Salmonella enterica Subspecies

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    M. 2002. Evolutionary genomics of Salmonella: genesubsystems technology. BMC Genomics 9:75. 23. Ochman H,Salmonella enterica. BMC Genomics 12:425. PubMed. 29. Falush

  3. 29The Journal of Cotton Science 10:2938 (2006) http://journal.cotton.org, The Cotton Foundation 2006

    E-Print Network [OSTI]

    Chee, Peng W.

    29The Journal of Cotton Science 10:29­38 (2006) http://journal.cotton.org, © The Cotton Foundation 2006 BREEDING AND GENETICS Predicting Intron Sites by Aligning Cotton ESTs with Arabidopsis Genomic DNADNA with their genomic coun- terpart. In cotton, this process is exacerbated by the scarcity of cotton genomic DNA

  4. Science Mathematics Engineering

    E-Print Network [OSTI]

    Hamlet, Richard

    Science Mathematics Engineering . ­ p.1 #12;Science Mathematics Engineering Science, Computer `Science', . ­ p.1 #12;Science Mathematics Engineering Science, Computer `Science', Mathematics, . ­ p.1 #12;Science Mathematics Engineering Science, Computer `Science', Mathematics, and Software Development

  5. Identification and characterization of insect-specific proteins by genome data analysis

    E-Print Network [OSTI]

    Zhang, Guojie; Wang, Hongsheng; Shi, Junjie; Wang, Xiaoling; Zheng, Hongkun; Wong, Gane Ka-Shu; Clark, Terry; Wang, Wen; Wang, Jun; Kang, Le

    2007-04-04T23:59:59.000Z

    ral ssBioMed CentBMC Genomics Open AcceResearch article Identification and characterization of insect-specific proteins by genome data analysis Guojie Zhang1,2,3, Hongsheng Wang1, Junjie Shi2, Xiaoling Wang2, Hongkun Zheng2, Gane Ka-Shu Wong2..., Terry Clark4, Wen Wang3, Jun Wang2,5 and Le Kang*1 Address: 1State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology Chinese Academy of Sciences, Haidian Beijing 100080, China, 2Beijing Institute of Genomics...

  6. Fueling Future with Algal Genomics

    SciTech Connect (OSTI)

    Grigoriev, Igor

    2012-07-05T23:59:59.000Z

    Algae constitute a major component of fundamental eukaryotic diversity, play profound roles in the carbon cycle, and are prominent candidates for biofuel production. The US Department of Energy Joint Genome Institute (JGI) is leading the world in algal genome sequencing (http://jgi.doe.gov/Algae) and contributes of the algal genome projects worldwide (GOLD database, 2012). The sequenced algal genomes offer catalogs of genes, networks, and pathways. The sequenced first of its kind genomes of a haptophyte E.huxleyii, chlorarachniophyte B.natans, and cryptophyte G.theta fill the gaps in the eukaryotic tree of life and carry unique genes and pathways as well as molecular fossils of secondary endosymbiosis. Natural adaptation to conditions critical for industrial production is encoded in algal genomes, for example, growth of A.anophagefferens at very high cell densities during the harmful algae blooms or a global distribution across diverse environments of E.huxleyii, able to live on sparse nutrients due to its expanded pan-genome. Communications and signaling pathways can be derived from simple symbiotic systems like lichens or complex marine algae metagenomes. Collectively these datasets derived from algal genomics contribute to building a comprehensive parts list essential for algal biofuel development.

  7. Comparative genomics of the Mycobacterium tuberculosis complex.

    E-Print Network [OSTI]

    Mostowy, Serge.

    2005-01-01T23:59:59.000Z

    ??The study of microbial evolution has been recently accelerated by the advent of comparative genomics, an approach enabling investigation of organisms at the whole-genome level. (more)

  8. Science Fairs for Science Literacy

    E-Print Network [OSTI]

    Mackey, Katherine; Culbertson, Timothy

    2014-01-01T23:59:59.000Z

    is supported by a National Science Foundation PostdoctoralT. Culbertson is a middle school science and math teacher.for the Advancement of Science (AAAS) (1990), Science for

  9. Wine Science Wine Sciencee Science

    E-Print Network [OSTI]

    Wine Science Wine Sciencee Science Thomas Henick-Kling Professor of Enology Director of Viticulture & Enology Program #12;Wine Science Wine Science Growth of Washington Wine Industry #12;Wine Science Wine Science Wine Grapes utilized 2007 2008 2009 2010 WA 127,000 145,000 156,000 160,000 NY 24,000 26,000 30

  10. 1 Biomedical Sciences BIOMEDICAL SCIENCES

    E-Print Network [OSTI]

    Vertes, Akos

    1 Biomedical Sciences BIOMEDICAL SCIENCES The interdisciplinary doctoral programs in the biomedical sciences are organized within the Institute for Biomedical Sciences. The first full year of study toward are admitted directly into the Institute for Biomedical Sciences through Columbian College of Arts and Sciences

  11. Closing Keynote Presentation on the Genomics of Energy and the Environment (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect (OSTI)

    Benner, Stephen [Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology] [Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology

    2012-03-22T23:59:59.000Z

    Steve Benner, a distinguished chemist at the Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology, provides the closing keynote address for the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  12. Closing Keynote Presentation on the Genomics of Energy and the Environment (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema (OSTI)

    Benner, Stephen [Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology

    2013-01-22T23:59:59.000Z

    Steve Benner, a distinguished chemist at the Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology, provides the closing keynote address for the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  13. Human genome. 1993 Program report

    SciTech Connect (OSTI)

    Not Available

    1994-03-01T23:59:59.000Z

    The purpose of this report is to update the Human Genome 1991-92 Program Report and provide new information on the DOE genome program to researchers, program managers, other government agencies, and the interested public. This FY 1993 supplement includes abstracts of 60 new or renewed projects and listings of 112 continuing and 28 completed projects. These two reports, taken together, present the most complete published view of the DOE Human Genome Program through FY 1993. Research is progressing rapidly toward 15-year goals of mapping and sequencing the DNA of each of the 24 different human chromosomes.

  14. Challenges in Whole-Genome Annotation of Pyrosequenced Eukaryotic Genomes

    SciTech Connect (OSTI)

    Kuo, Alan; Grigoriev, Igor

    2009-04-17T23:59:59.000Z

    Pyrosequencing technologies such as 454/Roche and Solexa/Illumina vastly lower the cost of nucleotide sequencing compared to the traditional Sanger method, and thus promise to greatly expand the number of sequenced eukaryotic genomes. However, the new technologies also bring new challenges such as shorter reads and new kinds and higher rates of sequencing errors, which complicate genome assembly and gene prediction. At JGI we are deploying 454 technology for the sequencing and assembly of ever-larger eukaryotic genomes. Here we describe our first whole-genome annotation of a purely 454-sequenced fungal genome that is larger than a yeast (>30 Mbp). The pezizomycotine (filamentous ascomycote) Aspergillus carbonarius belongs to the Aspergillus section Nigri species complex, members of which are significant as platforms for bioenergy and bioindustrial technology, as members of soil microbial communities and players in the global carbon cycle, and as agricultural toxigens. Application of a modified version of the standard JGI Annotation Pipeline has so far predicted ~;;10k genes. ~;;12percent of these preliminary annotations suffer a potential frameshift error, which is somewhat higher than the ~;;9percent rate in the Sanger-sequenced and conventionally assembled and annotated genome of fellow Aspergillus section Nigri member A. niger. Also,>90percent of A. niger genes have potential homologs in the A. carbonarius preliminary annotation. Weconclude, and with further annotation and comparative analysis expect to confirm, that 454 sequencing strategies provide a promising substrate for annotation of modestly sized eukaryotic genomes. We will also present results of annotation of a number of other pyrosequenced fungal genomes of bioenergy interest.

  15. SHORT REVIEW Ecological genomics: understanding gene and

    E-Print Network [OSTI]

    Kaufman, Glennis A.

    SHORT REVIEW Ecological genomics: understanding gene and genome function in the natural environment MC Ungerer, LC Johnson and MA Herman Division of Biology, Ecological Genomics Institute, Kansas State University, Manhattan, KS, USA The field of ecological genomics seeks to understand the genetic mechanisms

  16. Hindawi Publishing Corporation Comparative and Functional Genomics

    E-Print Network [OSTI]

    Newcastle upon Tyne, University of

    Hindawi Publishing Corporation Comparative and Functional Genomics Volume 2007, Article ID 47304, 7 pages doi:10.1155/2007/47304 Meeting Report eGenomics: Cataloguing Our Complete Genome Collection III, Michigan State University, East Lansing, MI 48824, USA 3 The Institute for Genomic Research, 9712 Medical

  17. A Statistical Framework for Spatial Comparative Genomics

    E-Print Network [OSTI]

    A Statistical Framework for Spatial Comparative Genomics Rose Hoberman May 2007 CMU-CS-07, or the U.S. Government. #12;Keywords: spatial comparative genomics, comparative genomics, gene clusters, max-gap clusters, gene teams, whole genome duplication, paralogons, synteny, ortholog detection #12

  18. Genomics and ornithology Scott V. Edwards

    E-Print Network [OSTI]

    Edwards, Scott

    REVIEW Genomics and ornithology Scott V. Edwards Received: 23 September 2007 / Accepted: 27 Genomics is revolutionizing ornithology in the same ways it is reinvigorating other biological disciplines. In this review, I will highlight applications of genomics and genomics technologies to the study of the ecology

  19. Extreme Genomics By Scouring the Genomes of 50 HIV-Resistant People, Study

    E-Print Network [OSTI]

    Dolbow, John

    Extreme Genomics By Scouring the Genomes of 50 HIV-Resistant People, Study Takes Aim at Rare Gene Genome Variation, and his colleagues think that the complete genome sequences of those fortunate few against the viral strain that usually infects humans. That's because the CCR5 protein is Extreme Genomics

  20. Is sustainability science really a science?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Is sustainability science really a science? Is sustainability science really a science? The team's work shows that although sustainability science has been growing explosively...

  1. Synthetic Genomics: Options for Governance

    E-Print Network [OSTI]

    Garfinkel, Michele

    2007-10-17T23:59:59.000Z

    Gene and genome synthesis, that is, constructing long stretches of DNA from constituent chemicals, provides scientists with new and unparalleled capabilities both for understanding biology and for using it for beneficial ...

  2. Earth Sciences Environmental Earth Sciences,

    E-Print Network [OSTI]

    Brierley, Andrew

    94 Earth Sciences­ Environmental Earth Sciences, Geology Degree options MGeol (Single Honours Degrees) Earth Sciences BSc (Single Honours Degrees) Environmental Earth Sciences Geology BSc (Joint placement. * The Geology and Environmental Earth Sciences degrees are accredited by the Geological Society

  3. 1 Political Science POLITICAL SCIENCE

    E-Print Network [OSTI]

    Vertes, Akos

    1 Political Science POLITICAL SCIENCE With Capitol Hill nearby and the White House just blocks away, GW is the ideal place to study political science. Students in the program benefit from rigorous study and behavioral sciences discipline in the Columbian College of Arts and Sciences, the program examines politics

  4. 1 Forensic Sciences FORENSIC SCIENCES

    E-Print Network [OSTI]

    Vertes, Akos

    1 Forensic Sciences FORENSIC SCIENCES As part of the Columbian College of Arts and Sciences' natural, mathematical and biomedical sciences programs, the forensic sciences program provides an understanding of the integration of forensic disciplines with the investigation of criminal activity, along

  5. FORENSIC SCIENCE About Forensic Science

    E-Print Network [OSTI]

    Su, Xiao

    Fact Sheet FORENSIC SCIENCE About Forensic Science: The Forensic Science program at SJSU offers: The SJSU Forensic Science program delivers coursework and training to · Empowergraduatestobecomeagentsofchangetorecognize, document and report errors and injustices in the practice of forensic science and crime scene

  6. Mapping our genes: The genome projects: How big, how fast

    SciTech Connect (OSTI)

    none,

    1988-04-01T23:59:59.000Z

    For the past 2 years, scientific and technical journals in biology and medicine have extensively covered a debate about whether and how to determine the function and order of human genes on human chromosomes and when to determine the sequence of molecular building blocks that comprise DNA in those chromosomes. In 1987, these issues rose to become part of the public agenda. The debate involves science, technology, and politics. Congress is responsible for /open quotes/writing the rules/close quotes/ of what various federal agencies do and for funding their work. This report surveys the points made so far in the debate, focusing on those that most directly influence the policy options facing the US Congress. Congressional interest focused on how to assess the rationales for conducting human genome projects, how to fund human genome projects (at what level and through which mechanisms), how to coordinate the scientific and technical programs of the several federal agencies and private interests already supporting various genome projects, and how to strike a balance regarding the impact of genome projects on international scientific cooperation and international economic competition in biotechnology. OTA prepared this report with the assistance of several hundred experts throughout the world. 342 refs., 26 figs., 11 tabs.

  7. E-Print Network 3.0 - analyses genomes comparison Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    genomes comparison Page: << < 1 2 3 4 5 > >> 1 A Novel Approach for Comparative Genomics Summary: is genome comparison good for?" Genome comparison is crucial for genome...

  8. Implications of structural genomics target selection strategies: Pfam5000, whole genome, and random approaches

    E-Print Network [OSTI]

    Chandonia, John-Marc; Brenner, Steven E.

    2004-01-01T23:59:59.000Z

    SK, Bonanno JB. Structural genomics. Methods Biochem AnalMizuguchi K. Structural genomics: an overview. Prog BiophysSE. A tour of structural genomics. Nat Rev Genet 2001;2(10):

  9. Computational Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computational Science and Engineering Petascale Initiative at LBNL Progress Report PI: Alice Koniges June 28, 2010 Computational Science and Engineering Petascale Initiative PI,...

  10. Science & Engineering

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Technology Delivering basic and applied science discoveries and innovating engineering R&D is the hallmark of the Science and Engineering division in support of INL's...

  11. Dissection of Plant Defense Mechanisms Using Chemical and Molecular Genomics

    E-Print Network [OSTI]

    Rodriguez-Salus, Melinda Sue

    2012-01-01T23:59:59.000Z

    of auxins by a chemical genomics approach." Journal ofadvances in chemical genomics." Current Medicinal Chemistrymolecular and chemical genomics." Phytopathology 97(7): S58-

  12. Comparative genomics reveals diversity among xanthomonads infecting tomato and pepper

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    Potnis et al. : Comparative genomics reveals diversity amongtomato and pepper. BMC Genomics Submit your next manuscriptpv. syringae Potnis et al. BMC Genomics 2011, 12:146 http://

  13. TOPSAN: a collaborative annotation environment for structural genomics.

    E-Print Network [OSTI]

    Weekes, Dana; Krishna, S; Bakolitsa, Constantina; Wilson, Ian A; Godzik, Adam; Wooley, John

    2010-01-01T23:59:59.000Z

    environment for structural genomics Dana Weekes 1 , S Srihigh-throughput structural genomics centers, despite theirbeing determined by structural genomics centers and high-

  14. Genomics of emerging infectious disease: A PLoS collection.

    E-Print Network [OSTI]

    Eisen, Jonathan A; MacCallum, Catriona J

    2009-01-01T23:59:59.000Z

    Origins and evolutionary genomics of the 2009 swine-originan Infectious Diseases Genomics Project predict and preventRavel J (2009) The role of genomics in the identification,

  15. Validation in Genomics: CpG Island Methylation Revisited

    E-Print Network [OSTI]

    Segal, Mark R

    2006-01-01T23:59:59.000Z

    analysis. In: Functional Genomics: Methods and Protocols, M.Segal: Validation in Genomics: CpG Island Methylationpackage and applications to genomics. Bioinformatics and

  16. Environmental Genomics Reveals a Single-Species Ecosystem Deep Earth

    E-Print Network [OSTI]

    Arkin, Adam P.

    2014-01-01T23:59:59.000Z

    Environmental Genomics Reveals a Single-Species EcosystemTechnology Program, DOE Joint Genomics Institute, Berkeley,and Environmental Research, Genomics:GTL program through

  17. MicrobesOnline: an integrated portal for comparative functional genomics

    E-Print Network [OSTI]

    Joachimiak, Marcin P.

    2014-01-01T23:59:59.000Z

    comparative functional genomics Marcin P. Joachimiak 1,2 ,for comparative functional genomics of bacteria and archaea.publicly avail- able functional genomics data from published

  18. Microbes Online: an integrated portal for comparative functional genomics

    E-Print Network [OSTI]

    Arkin, Adam P.

    2014-01-01T23:59:59.000Z

    comparative functional genomics of bacteria, archaea, fungifor comparative functional genomics Paramvir S. Dehal 1,2* (and Environmental Research, Genomics:GTL program through

  19. GOLD: The Genomes Online Database

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Kyrpides, Nikos; Liolios, Dinos; Chen, Amy; Tavernarakis, Nektarios; Hugenholtz, Philip; Markowitz, Victor; Bernal, Alex

    Since its inception in 1997, GOLD has continuously monitored genome sequencing projects worldwide and has provided the community with a unique centralized resource that integrates diverse information related to Archaea, Bacteria, Eukaryotic and more recently Metagenomic sequencing projects. As of September 2007, GOLD recorded 639 completed genome projects. These projects have their complete sequence deposited into the public archival sequence databases such as GenBank EMBL,and DDBJ. From the total of 639 complete and published genome projects as of 9/2007, 527 were bacterial, 47 were archaeal and 65 were eukaryotic. In addition to the complete projects, there were 2158 ongoing sequencing projects. 1328 of those were bacterial, 59 archaeal and 771 eukaryotic projects. Two types of metadata are provided by GOLD: (i) project metadata and (ii) organism/environment metadata. GOLD CARD pages for every project are available from the link of every GOLD_STAMP ID. The information in every one of these pages is organized into three tables: (a) Organism information, (b) Genome project information and (c) External links. [The Genomes On Line Database (GOLD) in 2007: Status of genomic and metagenomic projects and their associated metadata, Konstantinos Liolios, Konstantinos Mavromatis, Nektarios Tavernarakis and Nikos C. Kyrpides, Nucleic Acids Research Advance Access published online on November 2, 2007, Nucleic Acids Research, doi:10.1093/nar/gkm884]

    The basic tables in the GOLD database that can be browsed or searched include the following information:

    • Gold Stamp ID
    • Organism name
    • Domain
    • Links to information sources
    • Size and link to a map, when available
    • Chromosome number, Plas number, and GC content
    • A link for downloading the actual genome data
    • Institution that did the sequencing
    • Funding source
    • Database where information resides
    • Publication status and information

    (Specialized Interface)

  20. Uncovering the dynamics of genome function at the organismal scale using

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    and Page, Science, 2000 Genetronic Replicator Star Trek: TNG, 1992 #12;The genomic powerhouses ~20 facilitate the above ~25,000 genes #12;Workflow Data Capture Data Capture Data Storage (30 TB) Data Compression and Analysis Feature Extraction Data Storage (X TB) Schorr Center and OSG 0.5 TB/day Data

  1. Life sciences: Lawrence Berkeley Laboratory, 1988

    SciTech Connect (OSTI)

    Not Available

    1989-07-01T23:59:59.000Z

    Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program laboratory has emerged, in which the life sciences participate as a full partner. The LBL Human Genome Center is a contribution to the growing international effort to map the human genome. Its achievements represent LBL divisions, including Engineering, Materials and Chemical Sciences, and Information and Computing Sciences, along with Cell and Molecular Biology and Chemical Biodynamics. The Advanced Light Source Life Sciences Center will comprise not only beamlines and experimental end stations, but also supporting laboratories and office space for scientists from across the US. This effort reflects a confluence of scientific disciplines --- this time represented by individuals from the life sciences divisions and by engineers and physicists associated with the Advanced Light Source project. And finally, this report itself, the first summarizing the efforts of all four life sciences divisions, suggests a new spirit of cooperation. 30 figs.

  2. Addressing the Omics Data Explosion: a Comprehensive Reference Genome Representation and the Democratization of Comparative Genomics and Immunogenomics

    E-Print Network [OSTI]

    Nguyen, Ngan Kim

    2014-01-01T23:59:59.000Z

    Hubs: Web Accessible Browsers for Compar- ative Genomics 3.1Comparative Genomics Analyses . . . . . . . . . . . . . .browsers for comparative genomics B.1 E. coli KO11FL 162099

  3. Neal Lane: Confessions of a President's Science Advisor

    ScienceCinema (OSTI)

    Neal Lane

    2010-09-01T23:59:59.000Z

    Former science advisor to president Bill Clinton Neal Lane briefly reviews the history of the job of Science Advisor to the President and give some examples of issues he had to deal with when he was in that position, including climate change, stem cell research, the human genome, nanotechnology and research funding. He will also give his opinions about the present and future state of science in the U.S.

  4. The Genomes and Metagenomes (GEM) Catalogue (first presentation) and The ISA-GCDML Workshop (second presentation) (GSC8 Meeting)

    ScienceCinema (OSTI)

    Field, Dawn [NERC Centre for Ecology and Hydrology]; Sansone, Susanna [EBI

    2011-04-29T23:59:59.000Z

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding ''Research Coordination Network'' from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Dawn Field of the NERC Centre for Ecology & Hydrology briefly introduces the GEM Catalogue, followed by Susanna Sansone of the European Bioinformatics Institute who talks about the ISA-GCDML workshop at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

  5. The Genomes and Metagenomes (GEM) Catalogue (first presentation) and The ISA-GCDML Workshop (second presentation) (GSC8 Meeting)

    SciTech Connect (OSTI)

    Field, Dawn [NERC Centre for Ecology and Hydrology; Sansone, Susanna [EBI

    2009-09-09T23:59:59.000Z

    The Genomic Standards Consortium was formed in September 2005. It is an international, open-membership working body which promotes standardization in the description of genomes and the exchange and integration of genomic data. The 2009 meeting was an activity of a five-year funding ''Research Coordination Network'' from the National Science Foundation and was organized held at the DOE Joint Genome Institute with organizational support provided by the JGI and by the University of California - San Diego. Dawn Field of the NERC Centre for Ecology & Hydrology briefly introduces the GEM Catalogue, followed by Susanna Sansone of the European Bioinformatics Institute who talks about the ISA-GCDML workshop at the Genomic Standards Consortium's 8th meeting at the DOE JGI in Walnut Creek, Calif. on Sept. 9, 2009.

  6. Enhancer Identification through Comparative Genomics

    SciTech Connect (OSTI)

    Visel, Axel; Bristow, James; Pennacchio, Len A.

    2006-10-01T23:59:59.000Z

    With the availability of genomic sequence from numerousvertebrates, a paradigm shift has occurred in the identification ofdistant-acting gene regulatory elements. In contrast to traditionalgene-centric studies in which investigators randomly scanned genomicfragments that flank genes of interest in functional assays, the modernapproach begins electronically with publicly available comparativesequence datasets that provide investigators with prioritized lists ofputative functional sequences based on their evolutionary conservation.However, although a large number of tools and resources are nowavailable, application of comparative genomic approaches remains far fromtrivial. In particular, it requires users to dynamically consider thespecies and methods for comparison depending on the specific biologicalquestion under investigation. While there is currently no single generalrule to this end, it is clear that when applied appropriately,comparative genomic approaches exponentially increase our power ingenerating biological hypotheses for subsequent experimentaltesting.

  7. Political Science College of Arts and Sciences

    E-Print Network [OSTI]

    Collins, Gary S.

    Political Science College of Arts and Sciences Degree Options Bachelor of Arts in Political Science General Political Science Global Politics Political Science Pre-Law Minors Political Science Program Law Campaign worker Politics Marketing and sales Nonprofit administration Consultant Certification

  8. [Faculty of Science Information and Computing Sciences

    E-Print Network [OSTI]

    Löh, Andres

    [Faculty of Science Information and Computing Sciences] Terminating combinator parsers in Agda and Computing Sciences Utrecht University June 12, 2008 #12;[Faculty of Science Information and Computing Sciences] 2 Overview Totality Parser combinators Terminating combinator parsers #12;[Faculty of Science

  9. Faculty of Science Computer Science

    E-Print Network [OSTI]

    Faculty of Science Computer Science Computer software engineering, network and system analysis.uwindsor.ca/computerscience The University of Windsor offers a variety of computer science programs to prepare students for a career in the technology industry or in research and academia. A computer science degree provides an in-depth understanding

  10. Faculty of Science Computer Science

    E-Print Network [OSTI]

    Faculty of Science Computer Science Software engineering, network and system analysis continue a variety of computer science programs to prepare students for a career in the technology industry or in research and academia. A computer science degree provides an in-depth understanding of the fundamentals

  11. Earth Sciences Environmental Earth Sciences,

    E-Print Network [OSTI]

    Brierley, Andrew

    84 Earth Sciences­ Environmental Earth Sciences, Geology MGeol (Single Honours Degrees) Earth Sciences BSc (Single Honours Degrees) Environmental Earth Sciences Geology BSc (Joint Honours Degrees) and among the most research-intensive in Europe. Features * The Department of Earth and Environmental

  12. Faculty of Science Science Undergraduate

    E-Print Network [OSTI]

    Pedersen, Tom

    Faculty of Science Science Undergraduate Research Awards (SURA) What are Science Undergraduate by an endowment provided by the estate of the late Eva Moody allows the Faculty of Science to provide a number are directed at undergraduate students who wish to carry out a research project during the summer under

  13. Faculty of Science Environmental Science

    E-Print Network [OSTI]

    Faculty of Science Environmental Science If you have a natural curiosity and concern about the environment, Environmental Science offers you exciting career opportunities. It applies scientific tools from.uwindsor.ca/earth #12;Environmental Science We look forward to meeting you! You will receive a solid grounding

  14. Genome Engineering with TAL Effector Nucleases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genome Engineering with TAL Effector Nucleases Print Genome engineering (GE), an emerging discipline in which a DNA sequence is altered at a single position, has a wide variety of...

  15. GWIDD: Genome-wide protein docking database

    E-Print Network [OSTI]

    Kundrotas, Petras J.; Zhu, Zhengwei; Vasker, Ilya A.

    2009-11-09T23:59:59.000Z

    Structural information on interacting proteins is important for understanding life processes at the molecular level. Genome-wide docking database is an integrated resource for structural studies of proteinprotein interactions on the genome scale...

  16. Genome Size Varaiation in D. melanogaster

    E-Print Network [OSTI]

    Alfrejd, Benjamin

    2011-04-26T23:59:59.000Z

    in genome size may account for some of the missing heritability. We measured female genome sizes for 34 Drosophila melanogaster inbred strains that derived from isofemale lines established from a natural population in Raleigh, NC, in addition to a group...

  17. Unlocking the Secrets of the Genome

    E-Print Network [OSTI]

    Celniker, Susan E.

    The primary objective of the Human Genome Project was to produce high-quality sequences not just for the human genome but also for those of the chief model organisms: Escherichia coli, yeast (Saccharomyces cerevisiae), ...

  18. From genomics to chemical genomics: new developments in KEGG

    E-Print Network [OSTI]

    Minoru Kanehisa; Susumu Goto; Masahiro Hattori; Kiyoko F. Aoki-kinoshita; Masumi Itoh; Shuichi Kawashima; Toshiaki Katayama; Michihiro Araki; Mika Hirakawa

    2006-01-01T23:59:59.000Z

    The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interactions with the environment, as well as for medical, industrial and other practical applications. The KEGG resource

  19. The Genome of the Epsilonproteobacterial Chemolithoautotroph Sulfurimonas dentrificans

    E-Print Network [OSTI]

    Sievert, Stefan M.; USF Genomics Class

    2008-01-01T23:59:59.000Z

    10 , Jrg Simon 11 , and the USF Genomics Class 2, ? Biologyof coverage at the Production Genomics Facility of the Joint

  20. Genome Sequence of the Pea Aphid Acyrthosiphon The International Aphid Genomics Consortium"

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Genome Sequence of the Pea Aphid Acyrthosiphon pisum The International Aphid Genomics Consortium we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple

  1. Population genomics20-02-2009 Antnio Rodrigues; Bruno Santos / 59 Population Genomics

    E-Print Network [OSTI]

    Goldschmidt, Christina

    Population genomics20-02-2009 António Rodrigues; Bruno Santos / 59 Population Genomics 1 António Rodrigues (PDBC 2008) Bruno Santos (PDBC 2008) #12;Population genomics20-02-2009 António Rodrigues; Bruno Santos / 59 Contents 2 2 1000 genome project 1 Motivation and Introduction New generation sequencing

  2. Joint Genome Institute's Automation Approach and History

    E-Print Network [OSTI]

    Roberts, Simon

    2006-01-01T23:59:59.000Z

    Joint Genome Institutes Automation Approach and Historythroughput environment; automation does not necessarilyissues Islands of Automation modular instruments with

  3. UNL Core for Applied Genomics and Ecology

    E-Print Network [OSTI]

    Farritor, Shane

    UNL Core for Applied Genomics and Ecology Bioinformatics training Roche 454 GS-FLX Registration, Microbiomes, Variant Analysis, Whole Genomes, Transcriptomes Data Analysis and Statistics CAGE database and employer. University of Nebraska-Lincoln*Core for Applied Genomics and Ecology* 323 Filley Hall *Lincoln

  4. Bridging mycorrhizal genomics, metagenomics and forest ecology

    E-Print Network [OSTI]

    Pringle, Anne

    Meetings Bridging mycorrhizal genomics, metagenomics and forest ecology 6th New Phytologist of easily cultured saprotrophic fungi (among the first three published genomes were the models Saccharomyces or biotechnological interest, genomics is now poised to rapidly permeate the fields of fungal ecology and evolution

  5. Leading Edge Bacterial Genomics and Pathogen Evolution

    E-Print Network [OSTI]

    Mekalanos, John

    Leading Edge Review Bacterial Genomics and Pathogen Evolution David M. Raskin,1 Rekha Seshadri,2 Medical School, Boston, MA 02115, USA 2 The Institute for Genomic Research, 9712 Medical Center Drive.02.002 The availability of hundreds of bacterial genome sequences has altered the study of bacte- rial pathogenesis

  6. One day seminar: Genetics and Genomics of

    E-Print Network [OSTI]

    Brierley, Andrew

    SCHOOL OF MEDICINE One day seminar: Genetics and Genomics of Infectious Diseases Malaria and TB 14th June 2013 University of St Andrews - School of Medicine Pathogen genome research allows exquisite to understanding disease progression. Pathogen genome sequencing is accessible to most. Outputs have broad

  7. INVITED: Comparative Microbial Genomics Giri Narasimhan

    E-Print Network [OSTI]

    Narasimhan, Giri

    INVITED: Comparative Microbial Genomics Giri Narasimhan Bioinformatics Research Group (Bio, comparative genomics holds the keys to decipher and mine this wealth of information. We discuss the diverse ways in which the availability of comparative genomics data allows us to answer more questions

  8. Bioinformatics The Maize Genetics and Genomics Database.

    E-Print Network [OSTI]

    Brendel, Volker

    Bioinformatics The Maize Genetics and Genomics Database. The Community Resource for Access 500113260 (T.E.S.) The Maize Genetics and Genomics Database (MaizeGDB) serves the maize (Zea mays data types available through MaizeGDB. MISSION AND SCOPE The Maize Genetics and Genomics Database

  9. Microfluidic Devices for Genomic Analysis

    E-Print Network [OSTI]

    the puzzle of interactions between proteins is far more complicated than deciphering genomes, due to the lack, and industry. Fractionation of biological molecules, such as nucleic acids and proteins, plays a central role of proteins' equivalent of amplification, fractionation and sequencing techniques. Micro- and nano

  10. Nuclear Organization and Genome Function

    E-Print Network [OSTI]

    Corces, Victor G.

    Nuclear Organization and Genome Function Kevin Van Bortle and Victor G. Corces Department-range interactions and have proposed roles in nuclear organization. In this review, we explore recent findings for the roles of insulators in nuclear organization. 163 Annu.Rev.CellDev.Biol.2012.28:163-187.Downloadedfromwww

  11. TRENDS in Genetics Vol.18 No.11 November 2002 http://tig.trends.com 0168-9525/02/$ see front matter 2002 Elsevier Science Ltd. All rights reserved. PII

    E-Print Network [OSTI]

    Fernandez, Thomas

    matter © 2002 Elsevier Science Ltd. All rights reserved. PII: 555Opinion One result of genome-9525/02/$ ­ see front matter © 2002 Elsevier Science Ltd. All rights reserved. PII: S0168-9525(02)02765-8 Genotype

  12. Progress Report for Structural Genomics Science Theme, year 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 - SeptemberMicroneedles for4-16Hamada winsProgress Report Workgroup #3 LowAdvanced#:

  13. From Human Genome to Materials "Genome" | U.S. DOE Office of Science

    Office of Science (SC) Website

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear SecurityTensile Strain Switched5 Industrial CarbonArticles News(SC) CCIScatteringFacilitiesU.S.Frequently

  14. 10.1101/gr.133330.111Access the most recent version at doi: published online March 27, 2012Genome Res.

    E-Print Network [OSTI]

    Miska, Eric

    Kingdom; 5 Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland; 6 Functional Genomics Center, ETH and University of Zurich, 8057 Zurich, Switzerland; 7 Laval of Science, University of Zurich, 8057 Zurich, Switzerland; 10 Institute of Pharmaceutical Sciences, ETH

  15. Big Science

    ScienceCinema (OSTI)

    Dr. Thomas Zacharia

    2010-01-08T23:59:59.000Z

    Big science seeks big solutions for the most urgent problems of our times. Video courtesy Cray, Inc.

  16. Big Science

    SciTech Connect (OSTI)

    Dr. Thomas Zacharia

    2008-12-01T23:59:59.000Z

    Big science seeks big solutions for the most urgent problems of our times. Video courtesy Cray, Inc.

  17. The ecoresponsive genome of Daphnia pulex

    SciTech Connect (OSTI)

    Colbourne, John K.; Pfrender, Michael E.; Gilbert, Donald; Thomas, W. Kelley; Tucker, Abraham; Oakley, Todd H.; Tokishita, Shinichi; Aerts, Andrea; Arnold, Georg J.; Basu, Malay Kumar; Bauer, Darren J.; Caceres, Carla E.; Carmel, Liran; Casola, Claudio; Choi, Jeong-Hyeon; Detter, John C.; Dong, Qunfeng; Dusheyko, Serge; Eads, Brian D.; Frohlich, Thomas; Geiler-Samerotte, Kerry A.; Gerlach, Daniel; Hatcher, Phil; Jogdeo, Sanjuro; Krijgsveld, Jeroen; Kriventseva, Evgenia V; Kltz, Dietmar; Laforsch, Christian; Lindquist, Erika; Lopez, Jacqueline; Manak, Robert; Muller, Jean; Pangilinan, Jasmyn; Patwardhan, Rupali P.; Pitluck, Samuel; Pritham, Ellen J.; Rechtsteiner, Andreas; Rho, Mina; Rogozin, Igor B.; Sakarya, Onur; Salamov, Asaf; Schaack, Sarah; Shapiro, Harris; Shiga, Yasuhiro; Skalitzky, Courtney; Smith, Zachary; Souvorov, Alexander; Sung, Way; Tang, Zuojian; Tsuchiya, Dai; Tu, Hank; Vos, Harmjan; Wang, Mei; Wolf, Yuri I.; Yamagata, Hideo; Yamada, Takuji; Ye, Yuzhen; Shaw, Joseph R.; Andrews, Justen; Crease, Teresa J.; Tang, Haixu; Lucas, Susan M.; Robertson, Hugh M.; Bork, Peer; Koonin, Eugene V.; Zdobnov, Evgeny M.; Grigoriev, Igor V.; Lynch, Michael; Boore, Jeffrey L.

    2011-02-04T23:59:59.000Z

    This document provides supporting material related to the sequencing of the ecoresponsive genome of Daphnia pulex. This material includes information on materials and methods and supporting text, as well as supplemental figures, tables, and references. The coverage of materials and methods addresses genome sequence, assembly, and mapping to chromosomes, gene inventory, attributes of a compact genome, the origin and preservation of Daphnia pulex genes, implications of Daphnia's genome structure, evolutionary diversification of duplicated genes, functional significance of expanded gene families, and ecoresponsive genes. Supporting text covers chromosome studies, gene homology among Daphnia genomes, micro-RNA and transposable elements and the 46 Daphnia pulex opsins. 36 figures, 50 tables, 183 references.

  18. Studies on the integration pattern of FBDV genome in host cell DNA

    E-Print Network [OSTI]

    Baig, Mirza Amanatulla

    1992-01-01T23:59:59.000Z

    STUDIES ON THE INTEGRATION PATTERN OF FBDV GENOME IN HOST CELL DNA A Thesis by MIRZA AMANATULLA BAIG Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE May 1992 Major Subject: Veterinary Microbiology STUDIES ON THE INTEGRATION PA~ OF FBDV GENOME IN HOST CELL DNA A Thesis by MIRZA AMANATULLA BAIG Approved as to style and content by: David L. Grah m (Chair of Commi tee) Maurice C. mp...

  19. ComputationalComputational ScienceScience

    E-Print Network [OSTI]

    Hawick, Ken

    ComputationalComputational ScienceScience KenKen HawickHawick k.a.k.a.hawickhawick@massey.ac.nz@massey.ac.nz Massey UniversityMassey University #12;Computational Science / eScienceComputational Science / eScience Computational Science concerns the application of computer science to physics, mathematics, chemistry, biology

  20. 10. international mouse genome conference

    SciTech Connect (OSTI)

    Meisler, M.H.

    1996-12-31T23:59:59.000Z

    Ten years after hosting the First International Mammalian Genome Conference in Paris in 1986, Dr. Jean-Louis Guenet presided over the Tenth Conference at the Pasteur Institute, October 7--10, 1996. The 1986 conference was a satellite to the Human Gene Mapping Workshop and had approximately 50 attendees. The 1996 meeting was attended by 300 scientists from around the world. In the interim, the number of mapped loci in the mouse increased from 1,000 to over 20,000. This report contains a listing of the program and its participants, and two articles that review the meeting and the role of the laboratory mouse in the Human Genome project. More than 200 papers were presented at the conference covering the following topics: International mouse chromosome committee meetings; Mutant generation and identification; Physical and genetic maps; New technology and resources; Chromatin structure and gene regulation; Rate and hamster genetic maps; Informatics and databases; and Quantitative trait analysis.

  1. Genome Improvement at JGI-HAGSC

    SciTech Connect (OSTI)

    Grimwood, Jane: Schmutz, Jeremy, J.: Myers, Richard, M.

    2012-03-03T23:59:59.000Z

    Since the completion of the sequencing of the human genome, the JGI has rapidly expanded its scientific goals in several DOE mission-relevant areas. At the JGI-HAGSC, we have kept pace with this rapid expansion of projects with our focus on assessing, assembling, improving and finishing eukaryotic whole genome shotgun (WGS) projects for which the shotgun sequence is generated at the Production Genomic Facility (JGI-PGF). We follow this by combining the draft WGS with genomic resources generated at JGI-HAGSC or in collaborator laboratories (including BAC end sequences, genetic maps and FLcDNA sequences) to produce an improved draft sequence. For eukaryotic genomes important to the DOE mission, we then add further information from directed experiments to produce reference genomic sequences that are publicly available for any scientific researcher. Also, we have continued our program for producing BAC-based finished sequence, both for adding information to JGI genome projects and for small BAC-based sequencing projects proposed through any of the JGI sequencing programs. We have now built our computational expertise in WGS assembly and analysis and have moved eukaryotic genome assembly from the JGI-PGF to JGI-HAGSC. We have concentrated our assembly development work on large plant genomes and complex fungal and algal genomes.

  2. E-Print Network 3.0 - artificial genome model Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomes: Choices to Make The first sequenced genome of a plant, Summary: in plant genomics re- search. Many of the obvious candidates for genome sequencing, model species......

  3. E-Print Network 3.0 - applying whole-genome studies Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (Lec 19) Picture Copyright: AccessExcellence @ the National Museum of Health Summary: Genomics Comparison of whole genomes. - Whole genome sequencing - Whole genome annotation &...

  4. E-Print Network 3.0 - adaptive responses genomic Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Selected Topics in Molecular Biology Summary: genome variation - cancer genomes Genomics of the adaptive immune system Ancient genomes Synthetic... MOLECULAR BIOLOGY...

  5. ENVIRONMENTAL SCIENCE AND

    E-Print Network [OSTI]

    ENVIRONMENTAL SCIENCE AND MANAGEMENT www.esr.pdx.edu Undergraduate Program: Environmental Science an emphasis on natural sciences and mathematics (Environmental Science) or emphasis on policy, geography and social sciences (Environmental Studies). Undergraduate Degrees Offered: Environmental Science Bachelor

  6. Cassava Genomics: can genomic technology benefit smallholder farmers in Africa? (2014 DOE JGI Genomics of Energy & Environment Meeting)

    SciTech Connect (OSTI)

    Rounsley, Steve [University of Arizona

    2014-03-20T23:59:59.000Z

    Steve Rounsley of the University of Arizona speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

  7. Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect (OSTI)

    Zimmer, Carl [New York Times] [New York Times

    2012-03-20T23:59:59.000Z

    Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

  8. Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema (OSTI)

    Zimmer, Carl [New York Times

    2013-01-22T23:59:59.000Z

    Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

  9. Genome Announcement1 Draft genome sequence of the electricity producing3

    E-Print Network [OSTI]

    Hazen, Terry

    1 Genome Announcement1 2 Draft genome sequence of the electricity producing3 Thermincola potens of insoluble electron acceptors by model Gram-negative64 bacteria such as Geobacter or Shewanella species (4

  10. Processing Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Processing Science Related to the Electron Beam Melting Additive Manufacturing Process October 14 th , 2014 Ryan Dehoff Metal Additive Manufacturing Thrust Lead Manufacturing...

  11. What Makes Science, Science? Research, Shared Effort ... & A...

    Broader source: Energy.gov (indexed) [DOE]

    What Makes Science, Science? Research, Shared Effort ... & A New Office of Science Website What Makes Science, Science? Research, Shared Effort ... & A New Office of Science...

  12. Comparative Mapping of the Alpaca Genome

    E-Print Network [OSTI]

    Fagundes De Avila, Felipe

    2014-08-06T23:59:59.000Z

    Research Institute (NHGRI) at the National Institutes of Health (NIH) for low coverage (2X) whole genome sequencing, together with 21 other mammalian species. This was done primarily to use comparative genomic information to improve the annotation...; https://bacpac.chori.org/library.php?id=448) (Figure 5). Figure 5. Nyala's Accoyo Empress Carlotta. The first round of genome sequencing (VicPac1.0; http://www.ncbi.nlm. nih.gov/genome/905) was generated at the Broad Institute by whole...

  13. Diatom Genomics (2009 JGI User Meeting)

    ScienceCinema (OSTI)

    Ambrust, Ginger

    2011-04-25T23:59:59.000Z

    Ginger Armbrust from the University of Washington spoke about diatom genomics on March 26, 2009 at the DOE JGI User Meeting

  14. Generalized genetical genomics : advanced methods and applications.

    E-Print Network [OSTI]

    Li, Yang

    2010-01-01T23:59:59.000Z

    ??Generalized genetical genomics (GGG) is a systems genetics approach that combines the analysis of genetic variation with population-wide assessment of variation in molecular traits in (more)

  15. Bradbury Science Museum - Science on Wheels

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bradbury Science Museum - Science on Wheels Our Mission: To stimulate interest in and enthusiasm for science, technology, engineering and mathematics and promote public...

  16. Update on the Maize Genome Sequencing Project The Maize Genome Sequencing Project

    E-Print Network [OSTI]

    Brendel, Volker

    Update on the Maize Genome Sequencing Project The Maize Genome Sequencing Project Vicki L. Chandler Genome Sequencing Project. The momentum for this endeavor has been building within the maize (Zea mays- sion. This Update reviews the project goals and the expected deliverables deriving from the two funded

  17. GENOMIC RESOURCES NOTE Genomic Resources Notes accepted 1 February 201331 March

    E-Print Network [OSTI]

    Rieseberg, Loren

    GENOMIC RESOURCES NOTE Genomic Resources Notes accepted 1 February 201331 March 2013 GENOMIC RESOURCES DEVELOPMENT CONSORTIUM,1 MATTHEW G. KING,2 SE BASTIEN RENAUT,3 LOREN H. RIESEBERG2,4 and HEATHER C. ROWE3 1 Molecular Ecology Resources Editorial Office, 6270 University Blvd, Vancouver, BC V6T 1Z4

  18. Cognitive Science 1 Cognitive Science

    E-Print Network [OSTI]

    (Linguistics), Laurie Santos (Psychology), Brian Scassellati (Computer Science) Assistant Professors Daylian and cognition based on patterns of breakdown in pathology, computational and robotic research that strives

  19. Life sciences

    SciTech Connect (OSTI)

    Day, L. (ed.)

    1991-04-01T23:59:59.000Z

    This document is the 1989--1990 Annual Report for the Life Sciences Divisions of the University of California/Lawrence Berkeley Laboratory. Specific progress reports are included for the Cell and Molecular Biology Division, the Research Medicine and Radiation Biophysics Division (including the Advanced Light Source Life Sciences Center), and the Chemical Biodynamics Division. 450 refs., 46 figs. (MHB)

  20. Database Requirements for Workflow Management in a HighThroughput Genome Laboratory 1

    E-Print Network [OSTI]

    Bonner, Anthony

    @genome.wi.mit.edu 2 University of Toronto Department of Computer Science 10 King's College Rd Toronto, ON, Canada M5S constitutes an audit trail, or event history, and has much the same function as a laboratory notebook number P50 HG00098, and from the U.S. Department of Energy under contract DE­FG02­95ER62101. 1 #12

  1. ORIGINAL ARTICLE Comparative genomics of two newly isolated

    E-Print Network [OSTI]

    Alvarez-Cohen, Lisa

    ORIGINAL ARTICLE Comparative genomics of two newly isolated Dehalococcoides strains of Microbiology, Cornell University, Ithaca, NY, USA Comparative genomics of Dehalococcoides strains and an enrichment were performed using a microarray targeting genes from all available sequenced genomes

  2. UV Decontamination of MDA Reagents for Single Cell Genomics

    E-Print Network [OSTI]

    Lee, Janey

    2011-01-01T23:59:59.000Z

    Reagents for Single Cell Genomics Janey Lee 1* , Damon TigheReagents for Single Cell Genomics Janey Lee 1 , Damon TigheAbstract Single cell genomics, the amplification and

  3. Structural Genomics of Minimal Organisms: Pipeline and Results

    E-Print Network [OSTI]

    Kim, Sung-Hou

    2008-01-01T23:59:59.000Z

    of recombinant proteins. J. Struct. Funct. Genomics 5:69-74.proteins. J. Struct. Funct. Genomics 5:69-74. Oganesyan,Structural Genomics of Minimal Organisms: Pipeline and

  4. Comparative genomics reveals evidence of marine adaptation in Salinispora species.

    E-Print Network [OSTI]

    Penn, Kevin; Jensen, Paul R

    2012-01-01T23:59:59.000Z

    Orcutt B, et al: Ecological genomics of marine roseobacters.1037-1042. Penn and Jensen BMC Genomics 2012, 13:86 http://and Jensen: Comparative genomics reveals evidence of marine

  5. Evolutionary Genomics of Life in (and from) the Sea

    E-Print Network [OSTI]

    Boore, Jeffrey L.

    2009-01-01T23:59:59.000Z

    291: 1304-1351. Table 1. Genomics information on the webLBNL-59356 Evolutionary Genomics of Life in (and from) thean engine for comparative genomics. The six largest centers

  6. Phytozome: A Comparative Platform for Green Plant Genomics

    E-Print Network [OSTI]

    Goodstein, David M.

    2012-01-01T23:59:59.000Z

    a growing plant comparative genomics resource. Nucleic AcidsL.A. (2011) The Sol Genomics Network (solgenomics.net):for comparative plant genomics. Nucleic Acids Res, 36, D959-

  7. Defining Genome Project Standards in a New Era of Sequencing

    SciTech Connect (OSTI)

    Chain, Patrick [DOE-JGI

    2009-05-27T23:59:59.000Z

    Patrick Chain of the DOE Joint Genome Institute gives a talk on behalf of the International Genome Sequencing Standards Consortium on the need for intermediate genome classifications between "draft" and "finished"

  8. Genome sequence of the Brown Norway rat yields insights into

    E-Print Network [OSTI]

    Pachter, Lior

    Genome sequence of the Brown Norway rat yields insights into mammalian evolution Rat Genome Norway (BN) rat strain. The sequence represents a high-quality `draft' covering over 90% of the genome

  9. Target Selection and Deselection at the Berkeley Structural Genomics Center

    E-Print Network [OSTI]

    Chandonia, John-Marc; Kim, Sung-Hou; Brenner, Steven E.

    2005-01-01T23:59:59.000Z

    gene-set concept. Annu Rev Genomics Hum Genet 2000;1:99-116.SE. A tour of structural genomics. Nat Rev Genet 2001;2(10):M, Wang LK. Structural genomics: a pipeline for providing

  10. The common ground of genomics and systems biology

    E-Print Network [OSTI]

    Conesa, Ana; Mortazavi, Ali

    2014-01-01T23:59:59.000Z

    8/S2. Authors details Genomics of Gene Expression Lab,systems biology. Annu Rev. Genomics Hum. Genet 2001, 2:343-projection strategies. Genomics 2008, 92(6):373-83. 31.

  11. The Impact of Structural Genomics: Expectations and Outcomes

    E-Print Network [OSTI]

    Chandonia, John-Marc; Brenner, Steven E.

    2005-01-01T23:59:59.000Z

    Choi et al. , J Struct Funct Genomics 4, 31-4 (2003). H. M.Center for Structural Genomics, sequence families of unknownMCSG) Northeast Structural Genomics Consortium, Novel folds

  12. The Evolution of the Anopheles 16 Genomes Project

    E-Print Network [OSTI]

    Waterhouse, Robert

    We report the imminent completion of a set of reference genome assemblies for 16 species of Anopheles mosquitoes. In addition to providing a generally useful resource for comparative genomic analyses, these genome sequences ...

  13. Assistant Director Physical Science and Engineering

    E-Print Network [OSTI]

    Genomics Plant Genome Physics of the Universe Education & Workforce Dev. Research Business Models Global

  14. Science Learning+: Phase 1 projects Science Learning+

    E-Print Network [OSTI]

    Rambaut, Andrew

    Science Learning+: Phase 1 projects Science Learning+ Phase 1 projects 2 December 2014 #12..............................................................................................................4 Youth access and equity in informal science learning: developing a research and practice agenda..................................................................................................5 Enhancing informal learning through citizen science..............................................6

  15. CENTRE FOR SCIENCE EDUCATION SCIENCE AND TECHNOLOGY

    E-Print Network [OSTI]

    FOR SCIENCE EDUCATION SCIENCE AND TECHNOLOGY AARHUS UNIVERSITY 13 JUNE 2013 Project work CENTRE FOR SCIENCE EDUCATION SCIENCE AND TECHNOLOGY AARHUS UNIVERSITY 13 JUNE and ICT Sessions: Mondays, Wednesdays and Fridays kl. 9-16 ICT Development Project work: Tuesdays

  16. Bachelor of Science & Bachelor of Science (Technology)

    E-Print Network [OSTI]

    Waikato, University of

    Bachelor of Science & Bachelor of Science (Technology) SpecialiSationS Environmental Microbiology environment. This specialisation can be attached to the Environmental Sciences major. Environmental Modelling Sciences major. Land and Freshwater Environments This specialisation is for students interested

  17. Uses of antimicrobial genes from microbial genome

    DOE Patents [OSTI]

    Sorek, Rotem; Rubin, Edward M.

    2013-08-20T23:59:59.000Z

    We describe a method for mining microbial genomes to discover antimicrobial genes and proteins having broad spectrum of activity. Also described are antimicrobial genes and their expression products from various microbial genomes that were found using this method. The products of such genes can be used as antimicrobial agents or as tools for molecular biology.

  18. Genome Biology 2004, 5:343 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    ://genomebiology.com/2004/5/9/343 © 2004 BioMed Central Ltd A report on the Keystone Symposium `Structural Genomics', held-dollar-plus folly? Two concurrent Keystone Symposia, `Structural Genomics' and `Frontiers in Structural Biology set up an auto- mated pipeline to annotate proteins of known structure but unknown function. The push

  19. Genome of Geobacter sulfurreducens: Metal Reduction

    E-Print Network [OSTI]

    Lovley, Derek

    and in the generation of electricity. G. sulfurreducens, a member of the - Proteobacteria and of the family GeobacterGenome of Geobacter sulfurreducens: Metal Reduction in Subsurface Environments B. A. Methe´,1 * K. Utterback,1 S. E. Van Aken,1 D. R. Lovley,2 C. M. Fraser1 The complete genome sequence of Geobacter

  20. Natural Sciences Tripos EARTH SCIENCES

    E-Print Network [OSTI]

    Cambridge, University of

    . The majority of Cambridge graduates remain within geology. Exploration and production of oil and gas still is the science of the Earth. What is the Earth made of? What processes shape and change it? What's happened of processes, geology is a holistic science, integrating physics, chemistry and biology with the evidence

  1. The Arabidopsis lyrata genome sequence and the basis of rapid genome size change

    SciTech Connect (OSTI)

    Hu, Tina T.; Pattyn, Pedro; Bakker, Erica G.; Cao, Jun; Cheng, Jan-Fang; Clark, Richard M.; Fahlgren, Noah; Fawcett, Jeffrey A.; Grimwood, Jane; Gundlach, Heidrun; Haberer, Georg; Hollister, Jesse D.; Ossowski, Stephan; Ottilar, Robert P.; Salamov, Asaf A.; Schneeberger, Korbinian; Spannagl, Manuel; Wang, Xi; Yang, Liang; Nasrallah, Mikhail E.; Bergelson, Joy; Carrington, James C.; Gaut, Brandon S.; Schmutz, Jeremy; Mayer, Klaus F. X.; Van de Peer, Yves; Grigoriev, Igor V.; Nordborg, Magnus; Weigel, Detlef; Guo, Ya-Long

    2011-04-29T23:59:59.000Z

    In our manuscript, we present a high-quality genome sequence of the Arabidopsis thaliana relative, Arabidopsis lyrata, produced by dideoxy sequencing. We have performed the usual types of genome analysis (gene annotation, dN/dS studies etc. etc.), but this is relegated to the Supporting Information. Instead, we focus on what was a major motivation for sequencing this genome, namely to understand how A. thaliana lost half its genome in a few million years and lived to tell the tale. The rather surprising conclusion is that there is not a single genomic feature that accounts for the reduced genome, but that every aspect centromeres, intergenic regions, transposable elements, gene family number is affected through hundreds of thousands of cuts. This strongly suggests that overall genome size in itself is what has been under selection, a suggestion that is strongly supported by our demonstration (using population genetics data from A. thaliana) that new deletions seem to be driven to fixation.

  2. JGI Genomics and Bioinformatics for Undergraduate Educators Workshop...

    Broader source: Energy.gov (indexed) [DOE]

    JGI Genomics and Bioinformatics for Undergraduate Educators Workshop JGI Genomics and Bioinformatics for Undergraduate Educators Workshop March 23, 2013 7:00PM EDT to March 26,...

  3. DOE JGI Whole Genome Shotgun Sequencing, part 2

    ScienceCinema (OSTI)

    Miranda Harmon-Smith

    2010-09-01T23:59:59.000Z

    A Howard Hughes Medical Institute (HHMI) video production describing the Whole Genome Shotgun Sequencing process at the US Department of Energy's Joint Genome Institute (JGI).

  4. The Seattle Structure Genomics Center for Infectious Disease...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Seattle Structure Genomics Center for Infectious Disease (SSGCID). The Seattle Structure Genomics Center for Infectious Disease (SSGCID). Abstract: The NIAID-funded Seattle...

  5. Combining Functional and Structural Genomics to Sample the Essential...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Functional and Structural Genomics to Sample the Essential Burkholderia Structome. Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome....

  6. Comparative Omics-Driven Genome Annotation Refinement: Application...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Abstract: Genome sequencing continues to be a rapidly evolving technology, yet most downstream aspects of genome annotation pipelines remain relatively stable or are even being...

  7. SciTech Connect: Multiplex automated genome engineering

    Office of Scientific and Technical Information (OSTI)

    Multiplex automated genome engineering Citation Details In-Document Search Title: Multiplex automated genome engineering You are accessing a document from the Department of...

  8. aspergillus genome database: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and avoid outdated data. Heiko Mller 11 Integrative database analysis in structural genomics CiteSeer Summary: Abstract (2 sentences) An important aspect of structural genomics...

  9. DOE JGI Whole Genome Shotgun Sequencing, part 3

    ScienceCinema (OSTI)

    Miranda Harmon-Smith

    2010-09-01T23:59:59.000Z

    A Howard Hughes Medical Institute (HHMI) video production describing the Whole Genome Shotgun Sequencing process at the US Department of Energy's Joint Genome Institute (JGI).

  10. Functional Genomics of Nervous System Development and Disease .

    E-Print Network [OSTI]

    Miller, Michael Ryan

    2011-01-01T23:59:59.000Z

    ??The goal of functional genomics is to elucidate the relationship between an organism's genotype and phenotype. A key characteristic of functional genomics is the use (more)

  11. DOE JGI Whole Genome Shotgun Sequencing, part 1

    ScienceCinema (OSTI)

    Miranda Harmon-Smith

    2010-09-01T23:59:59.000Z

    A Howard Hughes Medical Institute (HHMI) video production describing the Whole Genome Shotgun Sequencing process at the US Department of Energy's Joint Genome Institute (JGI).

  12. Faculty of Science Computer Science Handbook

    E-Print Network [OSTI]

    Sun, Jing

    Faculty of Science Computer Science Handbook 2013 #12;Welcome to Computer Science Welcome from the Head of Department 2 What is Computer Science? 2 Careers in Computer Science 3 What can you do with a Computer Science degree? 4 Meet our students 5 Academic information Important dates 7 Admission

  13. Web of Science Welcome to the Web of Science................................................................................................ 2

    E-Print Network [OSTI]

    Huang, Su-Yun

    Web of Science #12; Welcome to the Web of Science................................................................................................ 2 Web of Science.............................................................................................. 4 Web of Science

  14. des Sciences le magazine des activits de diffusion des sciences

    E-Print Network [OSTI]

    Cerf, Nicolas

    Solvay ........................................................................ 17 Classes Sciences au

  15. Comparative genomics analysis of Liberibacter species to elucidate pathogenesis and culturability

    E-Print Network [OSTI]

    Leonard, Michael T.; Fagen, Jennie R.; McCullough, Connor M.; Davis-Richardson, Austin G.; Davis, Michael J.; Triplett, Eric W.

    2014-01-01T23:59:59.000Z

    Vol. 1 (2014) Comparative genomics analysis of Liberibacterof citrus, comparative genomics of this strain with other

  16. Genome Structure Gallery from the Mycobacterium Tuberculosis Structual Genomics Consortium

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The TB Structural Genomics Consortium works with the structures of proteins from M. tuberculosis, analyzing these structures in the context of functional information that currently exists and that the Consortium generates. The database of linked structural and functional information constructed from this project will form a lasting basis for understanding M. tuberculosis pathogenesis and for structure-based drug design. The Consortium's structural and functional information is publicly available. The Structures Gallery makes more than 650 total structures available by PDB identifier. Some of these are not consortium targets, but all are viewable in 3D color and can be manipulated in various ways by Jmol, an open-source Java viewer for chemical structures in 3D from http://www.jmol.org/

  17. COMPUTER SCIENCE EECS Department

    E-Print Network [OSTI]

    COMPUTER SCIENCE EECS Department The Electrical Engineering and Computer Science (EECS) Department at WSU offers undergraduate degrees in electrical engineering, computer engineering and computer science. The EECS Department offers master of science degrees in computer science, electrical engineering

  18. Computer Science UNDERGRADUATE

    E-Print Network [OSTI]

    Suzuki, Masatsugu

    447 Computer Science UNDERGRADUATE PROGRAMS The Department of Computer Science provides undergraduate instruction leading to the bachelor's degree in computer science. This program in computer science is accredited by the Computer Science Accreditation Board (CSAB), a specialized accrediting body recognized

  19. Genome resequencing in Populus: Revealing large-scale genome variation and implications on specialized-trait genomics

    SciTech Connect (OSTI)

    Muchero, Wellington [ORNL] [ORNL; Labbe, Jessy L [ORNL] [ORNL; Priya, Ranjan [University of Tennessee, Knoxville (UTK)] [University of Tennessee, Knoxville (UTK); DiFazio, Steven P [West Virginia University, Morgantown] [West Virginia University, Morgantown; Tuskan, Gerald A [ORNL] [ORNL

    2014-01-01T23:59:59.000Z

    To date, Populus ranks among a few plant species with a complete genome sequence and other highly developed genomic resources. With the first genome sequence among all tree species, Populus has been adopted as a suitable model organism for genomic studies in trees. However, far from being just a model species, Populus is a key renewable economic resource that plays a significant role in providing raw materials for the biofuel and pulp and paper industries. Therefore, aside from leading frontiers of basic tree molecular biology and ecological research, Populus leads frontiers in addressing global economic challenges related to fuel and fiber production. The latter fact suggests that research aimed at improving quality and quantity of Populus as a raw material will likely drive the pursuit of more targeted and deeper research in order to unlock the economic potential tied in molecular biology processes that drive this tree species. Advances in genome sequence-driven technologies, such as resequencing individual genotypes, which in turn facilitates large scale SNP discovery and identification of large scale polymorphisms are key determinants of future success in these initiatives. In this treatise we discuss implications of genome sequence-enable technologies on Populus genomic and genetic studies of complex and specialized-traits.

  20. Proteogenomics : applications of mass spectrometry at the interface of genomics and proteomics

    E-Print Network [OSTI]

    Castellana, Natalie

    2012-01-01T23:59:59.000Z

    of proteomics and genomics to unravel the specificities ofetry and comparative genomics to analyze multiple genomes,genome, Comp. Funct. Genomics, vol. 3, no. 3, pp. 244253,

  1. Science Museum

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nanotechnology and algae biofuels exhibits open July 26 at the Bradbury Science Museum July 22, 2013 LOS ALAMOS, N.M., July 22, 2013-Los Alamos National Laboratory's Bradbury...

  2. Science Museum

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Maintaining nuclear stability in times of transition focus of talk at Bradbury Science Museum January 9, 2014 First in series of evening lectures open to public LOS ALAMOS, N.M.,...

  3. Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

    E-Print Network [OSTI]

    2008-01-01T23:59:59.000Z

    siRNA-Based Functional Genomics of Pigmentation Identifiespoorly understood. Functional genomics based on RNA-mediatedof RNAi-based functional genomics to identify novel genes,

  4. Genome Sequence of the Palaeopolyploid soybean

    SciTech Connect (OSTI)

    Schmutz, Jeremy; Cannon, Steven B.; Schlueter, Jessica; Ma, Jianxin; Mitros, Therese; Nelson, William; Hyten, David L.; Song, Qijian; Thelen, Jay J.; Cheng, Jianlin; Xu, Dong; Hellsten, Uffe; May, Gregory D.; Yu, Yeisoo; Sakura, Tetsuya; Umezawa, Taishi; Bhattacharyya, Madan K.; Sandhu, Devinder; Valliyodan, Babu; Lindquist, Erika; Peto, Myron; Grant, David; Shu, Shengqiang; Goodstein, David; Barry, Kerrie; Futrell-Griggs, Montona; Abernathy, Brian; Du, Jianchang; Tian, Zhixi; Zhu, Liucun; Gill, Navdeep; Joshi, Trupti; Libault, Marc; Sethuraman, Anand; Zhang, Xue-Cheng; Shinozaki, Kazuo; Nguyen, Henry T.; Wing, Rod A.; Cregan, Perry; Specht, James; Grimwood, Jane; Rokhsar, Dan; Stacey, Gary; Shoemaker, Randy C.; Jackson, Scott A.

    2009-08-03T23:59:59.000Z

    Soybean (Glycine max) is one of the most important crop plants for seed protein and oil content, and for its capacity to fix atmospheric nitrogen through symbioses with soil-borne microorganisms. We sequenced the 1.1-gigabase genome by a whole-genome shotgun approach and integrated it with physical and high-density genetic maps to create a chromosome-scale draft sequence assembly. We predict 46,430 protein-coding genes, 70percent more than Arabidopsis and similar to the poplar genome which, like soybean, is an ancient polyploid (palaeopolyploid). About 78percent of the predicted genes occur in chromosome ends, which comprise less than one-half of the genome but account for nearly all of the genetic recombination. Genome duplications occurred at approximately 59 and 13 million years ago, resulting in a highly duplicated genome with nearly 75percent of the genes present in multiple copies. The two duplication events were followed by gene diversification and loss, and numerous chromosome rearrangements. An accurate soybean genome sequence will facilitate the identification of the genetic basis of many soybean traits, and accelerate the creation of improved soybean varieties.

  5. The Los Alamos Science Pillars The Science of Signatures

    SciTech Connect (OSTI)

    Smith, Joshua E. [Los Alamos National Laboratory; Peterson, Eugene J. [Los Alamos National Laboratory

    2012-09-13T23:59:59.000Z

    As a national security science laboratory, Los Alamos is often asked to detect and measure the characteristics of complex systems and to use the resulting information to quantify the system's behavior. The Science of Signatures (SoS) pillar is the broad suite of technical expertise and capability that we use to accomplish this task. With it, we discover new signatures, develop new methods for detecting or measuring signatures, and deploy new detection technologies. The breadth of work at Los Alamos National Laboratory (LANL) in SoS is impressive and spans from the initial understanding of nuclear weapon performance during the Manhattan Project, to unraveling the human genome, to deploying laser spectroscopy instrumentation on Mars. Clearly, SoS is a primary science area for the Laboratory and we foresee that as it matures, new regimes of signatures will be discovered and new ways of extracting information from existing data streams will be developed. These advances will in turn drive the development of sensing instrumentation and sensor deployment. The Science of Signatures is one of three science pillars championed by the Laboratory and vital to supporting our status as a leading national security science laboratory. As with the other two pillars, Materials for the Future and Information Science and Technology for Predictive Science (IS&T), SoS relies on the integration of technical disciplines and the multidisciplinary science and engineering that is our hallmark to tackle the most difficult national security challenges. Over nine months in 2011 and 2012, a team of science leaders from across the Laboratory has worked to develop a SoS strategy that positions us for the future. The crafting of this strategy has been championed by the Chemistry, Life, and Earth Sciences Directorate, but as you will see from this document, SoS is truly an Institution-wide effort and it has engagement from every organization at the Laboratory. This process tapped the insight and imagination of many LANL staff and managers and resulted in a strategy which focuses on our strengths while recognizing that the science of signatures is dynamic. This report highlights the interdependence between SoS, advances in materials science, and advances in information technology. The intent is that SoS shape and inform Los Alamos investments in nuclear forensics, nuclear diagnostics, climate, space, energy, and biosurveillence; the areas of leadership that you will read about in this strategy document. The Science of Signatures is still a relatively new strategic direction for the Laboratory. The primary purpose of this document is tell Laboratory staff how SoS is being managed and give them a chance to get involved. A second important purpose is to inform the Department of Energy and our customers of our capability growth in this important scientific area. Questions concerning the SoS strategy and input to it are welcomed and may be directed to any member of the SoS Leadership Council or to the Chemistry, Life, and Earth Science Directorate Office.

  6. www.emsl.pnnl.gov New Science, New Tools: GENOMIC SCIENCES

    E-Print Network [OSTI]

    of the Environmental TEM and Scanning/TEM permit the highest resolution imaging of biological samples. Combined

  7. Automatic annotation of organellar genomes with DOGMA

    SciTech Connect (OSTI)

    Wyman, Stacia; Jansen, Robert K.; Boore, Jeffrey L.

    2004-06-01T23:59:59.000Z

    Dual Organellar GenoMe Annotator (DOGMA) automates the annotation of extra-nuclear organellar (chloroplast and animal mitochondrial) genomes. It is a web-based package that allows the use of comparative BLAST searches to identify and annotate genes in a genome. DOGMA presents a list of putative genes to the user in a graphical format for viewing and editing. Annotations are stored on our password-protected server. Complete annotations can be extracted for direct submission to GenBank. Furthermore, intergenic regions of specified length can be extracted, as well the nucleotide sequences and amino acid sequences of the genes.

  8. Genome Engineering with TAL Effector Nucleases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals. |GenericGenomeGenomeGenome

  9. APPLIED GENOMICS TECHNOLOGY CENTER www.agtc.med.wayne.edu

    E-Print Network [OSTI]

    Berdichevsky, Victor

    APPLIED GENOMICS TECHNOLOGY CENTER www.agtc.med.wayne.edu CURRENT SERVICES CONTACT INFORMATION Dr. Susan J. Land, Ph.D. Laboratory Director ABOUT THE FACILITY The Applied Genomics Technology Center (AGTC-of-the-art, fee-for-service genomics center that provides a wide range of genomic technologies to the medical

  10. Functional Genomics: It's All How You Read It

    E-Print Network [OSTI]

    Boguski, Mark S.

    Functional Genomics: It's All How You Read It Philip Hieter and Mark Boguski "Functional genomics to functional genomics? An informal poll of colleagues indicates that the term is widely used, but has many genomics websites that have sprung up over the last 12 months clearly demonstrates that interpretations

  11. Phylogenetics of modern birds in the era of genomics

    E-Print Network [OSTI]

    Edwards, Scott

    Review Phylogenetics of modern birds in the era of genomics Scott V. Edwards*, W. Bryan Jennings and maturation of the genomics era, the completion of the chicken genome and a suite of technologies that promise genomics strategies, including adoption of objective quality scores for sequence data, analysis

  12. Target selection and current status of structural genomics for the

    E-Print Network [OSTI]

    Babu, M. Madan

    33 Target selection and current status of structural genomics for the completed microbial genomes 3.2 Structural status of completed microbial genomes in the PDB................ 3.3 Metabolic pathways as targets for structural genomics.......................... 3.3.1 Glycolytic pathway

  13. An Integrated Program in Microbial Genome Sequencing and Analysis

    SciTech Connect (OSTI)

    Claire M. Fraser, Ph.D.; J.E. Eisen, Ph.D.; W. Nierman, Ph.D.; K. Nelson, Ph.D.; H. Tettelin, Ph.D.; J. Heidelberg, Ph.D.; O. White, Ph.D.; B. Methe, Ph.D.; N. El-Sayed, Ph.D.; S. Gill, Ph.D.; S. Peterson, Ph.D.; J. Quackenbush, Ph.D.; T. Read, Ph.D.

    2005-11-30T23:59:59.000Z

    Under this award, numerous genome sequences were generated, analyzed, published and made publicly available.

  14. Letter to the Editor Toward Sequencing Cotton (Gossypium) Genomes

    E-Print Network [OSTI]

    Chee, Peng W.

    Letter to the Editor Toward Sequencing Cotton (Gossypium) Genomes Despite rapidly decreasing costs complex ge- nomes de novo. The cotton (Gossypium spp.) genomes represent a challenging case. To this end, a coalition of cotton genome scientists has developed a strategy for sequencing the cotton genomes, which

  15. BER Science Network Requirements

    E-Print Network [OSTI]

    Dart, Eli

    2011-01-01T23:59:59.000Z

    of Energy, Office of Science, Office of Advanced Scientificthe Directors of the Office of Science, Office of Advanced5 Simulation Data Key Remote Science Drivers Instruments and

  16. Writing for Science Literacy

    E-Print Network [OSTI]

    Chamberlin, Shannon Marie; Chamberlin, Shannon Marie

    2012-01-01T23:59:59.000Z

    literacy: 25 years of language arts and science research.International Journal of Science Education, 25, 689-725.possibilities: Language and science literacyempowering

  17. ORISE: Forensic Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Forensic Science Forensic Science The Oak Ridge Institute for Science and Education (ORISE) provides direct forensic analytical support, consulting and training services to United...

  18. The Science of Science Dr. Katy Brner

    E-Print Network [OSTI]

    Menczer, Filippo

    1 The Science of Science Dr. Katy Börner Cyberinfrastructure for Network Science Center, Director Information Visualization Laboratory, Director School of Library and Information Science Indiana University February 20th, 2008 Computational Scientometrics: Studying Science by Scientific Means Börner, Katy, Chen

  19. History of Science 157 Sociology of Science

    E-Print Network [OSTI]

    Shapin, Steven

    1 History of Science 157 Sociology of Science Fall 2009 Steven Shapin Science Center 469 Tuesdays to thinking about science, its historical development, its relations to society and other forms of culture: Science Center 451 Office hours: Mondays 8:30 -> 10.15, or by arrangement #12;2 E-mail: shapin

  20. Computer Science 1 Department of Computer Science

    E-Print Network [OSTI]

    Steinberg, Louis

    Computer Science 1 Department of Computer Science School of Arts and Science www.cs.rutgers.edu Presented by Prof. Louis Steinberg www.cs.rutgers.edu/~lou #12;Computer Science 2 It's NOT just programming, maintenance ·devising computing solutions for cutting edge problems What is Computer Science? #12;Computer

  1. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    , College of Health Sciences. "Innovative Ways to Address Idaho's Healthcare Needs: Long-Term CareCollege of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection February 2011 Volume IX (3) Since the last COHS newsletter, the faculty

  2. Accelerating Biofuel Feedstock Crop Improvement with Miscanthus Genomics (2014 DOE JGI Genomics of Energy & Environment Meeting)

    SciTech Connect (OSTI)

    Swaminathan, Kankshita [Energy Biosciences Institute

    2014-03-20T23:59:59.000Z

    Kankshita Swaminathan of the Energy Biosciences Institute speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

  3. Application of comparative genomics for detection of genomic features and transcriptional regulatory elements.

    E-Print Network [OSTI]

    Lu, Hong

    2011-01-01T23:59:59.000Z

    ??In the wake of advanced DNA sequencing technology, a large number of bacterial, animal, and plant genomes have now been completely sequenced and deposited into (more)

  4. Justice and the Human Genome Project

    SciTech Connect (OSTI)

    Murphy, T.F.; Lappe, M. [eds.] [eds.

    1992-12-31T23:59:59.000Z

    Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

  5. Justice and the Human Genome Project

    SciTech Connect (OSTI)

    Murphy, T.F.; Lappe, M. (eds.)

    1992-01-01T23:59:59.000Z

    Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

  6. Performance Comparison of Two Genome Partitioning Platforms

    SciTech Connect (OSTI)

    Armstrong, Joe [Genome Center at Washington University in St. Louis School of Medicine

    2009-05-29T23:59:59.000Z

    Jon Armstrong from the Genome Center at Washington University in St. Louis School of Medicine speaks at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

  7. Computational regulatory genomics : motifs, networks, and dynamics

    E-Print Network [OSTI]

    Kheradpour, Pouya

    2012-01-01T23:59:59.000Z

    Gene regulation, the process responsible for taking a static genome and producing the diversity and complexity of life, is largely mediated through the sequence specific binding of regulators. The short, degenerate nature ...

  8. Next-generation information systems for genomics

    E-Print Network [OSTI]

    Mungall, Christopher

    2011-06-27T23:59:59.000Z

    The advent of next-generation sequencing technologies is transforming biology by enabling individual researchers to sequence the genomes of individual organisms or cells on a massive scale. In order to realize the ...

  9. Prokaryotic Genomes from Microbes Online Database

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Alm, Eric J.; Huang, Katherine H.; Price, Morgan N.; Koche, Richard P.; Keller, Keith; Dubchak, Inna L.; Arkin, Adam P.

    To describe the potential functions of genes, MicrobesOnline includes protein family analyses (from InterPro and COG), metabolic maps (from KEGG), links to research papers (from UniProt and PubMed), and operon predictions for every genome. To examine each gene's evolutionary history, MicrobesOnline includes precomputed phylogenetic trees for all the gene families. It displays gene trees with genomic context or it compares the gene tree to the species tree. The tools provided with MicrobesOnline allow users to: compute customized motifs, sequence alignments, and phylogenetic trees change expression patterns in metabolic maps annotate genes in various ways The database contains more than 430 genomes. A browse tree tool and a genome browser are available, along with specialized search capabilities. (Specialized Interface)

  10. Comparative genomics and bioenergetics Jose Castresana *

    E-Print Network [OSTI]

    Castresana, Jose

    Review Comparative genomics and bioenergetics Jose Castresana * European Molecular Biology conclusions about the phylogenetic distribution and evolution of bioenergetic pathways to be drawn conservation used by prokaryotes. In addition, a thorough phylogenetic analysis of other bioenergetic protein

  11. Cancer Vulnerabilities Unveiled by Genomic Loss

    E-Print Network [OSTI]

    Nijhawan, Deepak

    Due to genome instability, most cancers exhibit loss of regions containing tumor suppressor genes and collateral loss of other genes. To identify cancer-specific vulnerabilities that are the result of copy number losses, ...

  12. Genomic aggregation effects and Simpson's paradox

    E-Print Network [OSTI]

    Brimacombe, Michael

    2014-01-08T23:59:59.000Z

    Genomic studies have become commonplace, with thousands of gene expressions typically collected on single or multiple platforms and analyzed. Unaccounted time-ordered or epigenetic aspects of genetic expression may lead ...

  13. DOE Joint Genome Institute 2008 Progress Report

    E-Print Network [OSTI]

    Gilbert, David

    2009-01-01T23:59:59.000Z

    Genomics of cellulosic biofuels. Nature, 454 (7206):841-845,2008 Termite Bellies and Biofuels (Published in Smithsonian,in the quest for viable biofuels. An estimated 10,000 marine

  14. 1st Genomics-Bioinformatics Day on "Comparative Genomics" April 24th 2003 in the Medawar Building in the

    E-Print Network [OSTI]

    Goldschmidt, Christina

    1st Genomics-Bioinformatics Day on "Comparative Genomics" April 24th 2003 in the Medawar Building. There is a need, however, for researchers interested in genomics and bioinformatics to meet, so Jotun Hein, Richard Mott and Chris Ponting have organised the first Genomics/Bioinformatics day. It is our intention

  15. Cheminformatics for genome-scale metabolic reconstructions

    E-Print Network [OSTI]

    May, John W.

    2015-01-06T23:59:59.000Z

    .15 Problematic tetrahedral stereocentres . . . . . . . . . . . . . . . . . . . . . 190 6.16 Corrupting stereochemistry depiction . . . . . . . . . . . . . . . . . . . . 192 6.17 Variable CIP descriptors of myo-inositol using JChem . . . . . . . . . . . 193 6... of Biological Interest CIP Cahn-Ingold-Prelog EC Enzyme Commission GEM Genome-scale metabolic model GPR Gene-Protein-Reaction InChI IUPAC International Chemical Identifier KEGG Kyoto Encyclopedia of Genes and Genomes MIRIAM Minimum Information Required...

  16. Science Highlights

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administrationcontroller systemsBi (2) Sr (2)Science Highlight Archives: 1995-2004Science Highlights

  17. Science Magazine

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administrationcontroller systemsBi (2) Sr (2)Science Highlight Archives:2 MAY 2013 VOL 340 SCIENCE

  18. COMPUTER SCIENCE INFORMATION TECHNOLOGY

    E-Print Network [OSTI]

    Dunstan, Neil

    COMPUTER SCIENCE and INFORMATION TECHNOLOGY POSTGRADUATE STUDIES 2006 School of Mathematics, Statistics and Computer Science The University of New England Armidale, NSW, Australia Printed courses in computer science and the graduate level topics in computer science which are offered

  19. Indiana University Cognitive Science

    E-Print Network [OSTI]

    Indiana University

    Indiana University Cognitive Science Exploring the Science of Learning Representations Simulations in science. How can simulations best be designed to enhance science learning and transfer? Computer Modeling Transfer Complex Systems Perception Which representations might help your students learn about

  20. Integrated Microbial Genomes (IMG) System from the DOE Joint Genome Institute (JGI)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The integrated microbial genomes (IMG) system is a data management, analysis and annotation platform for all publicly available genomes. IMG contains both draft and complete JGI microbial genomes integrated with all other publicly available genomes from all three domains of life, together with a large number of plasmids and viruses. IMG provides tools and viewers for analyzing and annotating genomes, genes and functions, individually or in a comparative context. Since its first release in 2005, IMG's data content and analytical capabilities have been constantly expanded through quarterly releases. IMG is provided by the DOE-Joint Genome Institute (JGI) and is available from http://img.jgi.doe.gov. [Abstract from The integrated microbial genomes (IMG) system in 2007: data content and analysis tool extensions; Victor M. Markowitz, Ernest Szeto, Krishna Palaniappan, Yuri Grechkin, Ken Chu, I-Min A. Chen, Inna Dubchak, Iain Anderson, Athanasios Lykidis, Konstantinos Mavromatis, Natalia N. Ivanova and Nikos C. Kyrpides; Nucleic Acids Research, 2008, Vol. 36. (Database Issue) See also the companion system, Integrated Microbial Genomes with Microbiome Samples.

  1. Applications of the pipeline environment for visual informatics and genomics computations

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    for visual informatics and genomics computations. BMCfor visual informatics and genomics computations Ivo D DinovContemporary informatics and genomics research require

  2. Genomics-based breeding in forest trees: are we there yet?

    E-Print Network [OSTI]

    Neale, David

    2011-01-01T23:59:59.000Z

    PRESENTATION Open Access Genomics-based breeding in forestEfforts to realize genomics-based breeding in conifer treeUSDA. The Conifer Translational Genomics Network Coordinated

  3. A Novel Candidate Vaccine for Cytauxzoonosis Inferred from Comparative Apicomplexan Genomics

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    from Comparative Apicomplexan Genomics Jaime L. Tarigo 1 ,the use of comparative genomics to computationally andthe use of comparative genomics as an accelerated path to

  4. From Benefit Sharing to Power Sharing: Partnership Governance in Population Genomics Research

    E-Print Network [OSTI]

    Winickoff, David E

    2008-01-01T23:59:59.000Z

    T. Greely, Iceland's Plan for Genomics Research: Facts andMike Fortun, Promising Genomics: Iceland and deCODE Geneticsabout commercialization in genomics research. 18 In this

  5. Comparative genomics of xylose-fermenting fungi for enhanced biofuel production

    E-Print Network [OSTI]

    Wohlbach, Dana J.

    2011-01-01T23:59:59.000Z

    et al. (2009) Comparative genomics of the fungal pathogensComparative genomics of xylose-fermenting fungi for enhancedapplications. BMC Genomics Wisselink HW, Toirkens MJ, Wu Q,

  6. Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters

    E-Print Network [OSTI]

    2006-01-01T23:59:59.000Z

    Metabolic Complementarity and Genomics of the Dual BacterialMetabolic complementarity and genomics of the dual bacterialthe other. ) Comparative genomics. The predicted proteomes

  7. RegPredict: an integrated system for regulon inference in prokaryotes by comparative genomics approach

    E-Print Network [OSTI]

    Novichkov, Pavel S.

    2010-01-01T23:59:59.000Z

    motifs by comparative genomics. Nucleic Acids Res. , 28,M.S. (2009) Comparative genomics of regulation of fatty acidcomparative and functional genomics. Nucleic Acids Res. ,

  8. E-Print Network 3.0 - acyrthosiphon pisum genome Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mathematics 6 Genome Sequence of the Pea Aphid Acyrthosiphon The International Aphid Genomics Consortium" Summary: Genome Sequence of the Pea Aphid Acyrthosiphon pisum The...

  9. Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets

    E-Print Network [OSTI]

    Ho, Hsiang; Milenkovic, Tijana; Memisevic, Vesna; Aruri, Jayavani; Przulj, Natasa; Ganesan, Anand K

    2010-01-01T23:59:59.000Z

    components within functional genomics datasets BMC SystemssiRNA-based functional genomics of pigmentation identifiesrelated functional genomics data. J R Soc Interface Motulsky

  10. E-Print Network 3.0 - array identifies genomic Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    20102011 Titre du projet DEVELOPMENT OF AN INTERACTIVE GENOME BROWSER, Summary: of genomics data (such as filtering, smoothing, selection and crossing of genomic data) (iii)...

  11. Evolutionary genomics of divergence and adaptation within the model fungi Neurospora crassa and Neurospora tetrasperma

    E-Print Network [OSTI]

    Ellison, Christopher

    2011-01-01T23:59:59.000Z

    Taylor JW. 2011. Population genomics and local adaptation inpromise of population genomics: from genotyping to genomeera. Annual Review of Genomics and Human Genetics 11:265-89.

  12. Discovery of Fungal Cell Wall Components Using Evolutionary and Functional Genomics

    E-Print Network [OSTI]

    Sain, Divya

    2013-01-01T23:59:59.000Z

    profiling and comparative genomics approaches." Eukaryotcerevisiae." Comp Funct Genomics 2(3): 124-42. Dinsdale, E.profiling and comparative genomics approaches." Eukaryot

  13. Applications of the Pipeline Environment for Visual Informatics and Genomics Computations

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    for visual informatics and genomics computations. BMCfor visual informatics and genomics computations Ivo D DinovContemporary informatics and genomics research require

  14. Environmental genomics reveals a single species ecosystem deep within the Earth

    E-Print Network [OSTI]

    Chivian, Dylan

    2008-01-01T23:59:59.000Z

    Environmental genomics reveals a single species ecosystemMaterial for Environmental genomics reveals a single speciesTechnology Program, DOE Joint Genomics Institute, Berkeley,

  15. E-Print Network 3.0 - aphid genome absence Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2 3 4 5 > >> 1 Genome Sequence of the Pea Aphid Acyrthosiphon The International Aphid Genomics Consortium" Summary: Genome Sequence of the Pea Aphid Acyrthosiphon pisum The...

  16. MicrobesOnline: an integrated portal for comparative and functional genomics

    E-Print Network [OSTI]

    Dehal, Paramvir

    2013-01-01T23:59:59.000Z

    for comparative and functional genomics Paramvir S. DehalUS Department of Energy Genomics: GTL program (grant DE-approach to comparative genomics, including a tree-based

  17. Pigeonpea genomics initiative (PGI): an international effort to improve crop productivity of pigeonpea (Cajanus cajan L.)

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    009-9327-2 Pigeonpea genomics initiative (PGI): anIndia R. K. Varshney (&) Genomics Towards Gene Discoverycrop legume. To enable genomics-assisted breeding in this

  18. Comparative genomics of metabolic capacities of regulons controlled by cis-regulatory RNA motifs in bacteria

    E-Print Network [OSTI]

    Sun, Eric I; Leyn, Semen A; Kazanov, Marat D; Saier, Milton H; Novichkov, Pavel S; Rodionov, Dmitry A

    2013-01-01T23:59:59.000Z

    RH, Breaker RR: Comparative genomics reveals 104 candidateof transporters. BMC Genomics 2008, 9:330. 16. Green NJ,in proteobacteria: comparative genomics analysis. FEMS

  19. E-Print Network 3.0 - accessing integrated genomic Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cancer Cytogenomics Microarray Consortium August 5th, 2010 UCSC Genome and Cancer... Genomics Browsers 12;UCSC Genome Browser ... Source: Goldman, Steven A. - Division of Cell...

  20. Discovering and validating biological hypotheses from coherent patterns in functional genomics data

    E-Print Network [OSTI]

    Joachimiak, Marcin Pawel

    2008-01-01T23:59:59.000Z

    patterns in functional genomics data Marcin P. Joachimiakpatterns in functional genomics data Marcin P. Joachimiakand Environmental Research, Genomics Program:GTL through

  1. Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies

    E-Print Network [OSTI]

    2009-01-01T23:59:59.000Z

    J Struct Funct Genomics (2009) 10:107125 DOIannotation for the structural genomics of the amidohydrolaseCenter for Structural Genomics (NYSGXRC) that aims to

  2. The development and application of an integrated functional genomics platform in Desulfovibrio desulfuricans G20

    E-Print Network [OSTI]

    Deutschbauer, Adam

    2014-01-01T23:59:59.000Z

    integrated functional genomics data will be used to build aan integrated functional genomics platform in Desulfovibrioand Environmental Research, Genomics:GTL program through

  3. Discovering and validating biological hypotheses from coherent patterns in functional genomics data using associative biclustering

    E-Print Network [OSTI]

    Joachimiak, Marcin P.

    2014-01-01T23:59:59.000Z

    patterns in functional genomics data using associativeand Environmental Research, Genomics:GTL program throughof Energy Functional genomics confronts researchers with a

  4. Update on the Pfam5000 Strategy for Selection of Structural Genomics Targets

    E-Print Network [OSTI]

    Chandonia, John-Marc; Brenner, Steven E.

    2005-01-01T23:59:59.000Z

    Mizuguchi, "Structural genomics: an overview," Prog BiophysA tour of structural genomics," Nat Rev Genet, vol. 2, pp.Montelione, "Structural genomics: an approach to the protein

  5. Comparative functional genomics of energy metabolism and insulin resistance in mammalian systems

    E-Print Network [OSTI]

    Hsiao, Albert

    2005-01-01T23:59:59.000Z

    oftwo-channelfunctionalgenomicsdata. (inreview). anddifferentiation. Genomics,2004. 84 (5):p. 876-ComparativeFunctionalGenomics ofEnergyMetabolismand

  6. Resource for the exploration of regulons accurately predicted by the methods of comparative genomics

    E-Print Network [OSTI]

    Novichkov, Pavel S.

    2014-01-01T23:59:59.000Z

    the methods of comparative genomics. Pavel S. Novichkov 1 ,Environmental Research, Genomics:GTL program through con-a computational comparative genomics approach is coming of

  7. Evolutionary Study of Genome Features in Cereals: a Focus on Endogenous Small RNA Generation

    E-Print Network [OSTI]

    Nohzadeh-Malakshah, Sahar

    2012-01-01T23:59:59.000Z

    overlapping genes in Metazoa. In BMC Genomics, pp. 174.B. (2012). Compressive genomics. In Nat Biotechnol , pp.Ibarra, J. (2011). Crop genomics: advances and applications.

  8. ESPP Functional Genomics and Imaging Core: Cell wide analysis of Metal-Reducing Bacteria

    E-Print Network [OSTI]

    Mukhopadhyay, Aindrila

    2014-01-01T23:59:59.000Z

    and Environmental Research, Genomics:GTL Program throughESPP Functional Genomics and Imaging Core: Cell widemetals. The Functional Genomics and Imaging Core (FGIC)

  9. Clustering and Registration of Functional Data with Applications in Time Course Genomics Data

    E-Print Network [OSTI]

    Zhang, Yafeng

    2014-01-01T23:59:59.000Z

    of Clustering Methods for Time Course Genomics Data . .Methods for Time Course Genomics Data. To be submitted S.human subjects. BMC Genomics, 13, 2012. 636. Kongming Wang

  10. A Tomato Detached Leaf Assay for Chemical Genomics of an HLB Model System

    E-Print Network [OSTI]

    Patne, S.; Eulgem, T.; Roose, M. L.

    2014-01-01T23:59:59.000Z

    Leaf Assay for Chemical Genomics of an HLB Model Systemapproach known as chemical genomics with Tomato Psyllida model of HLB. Chemical genomics involves three key stages

  11. DOUBLE MAJORS Imaging Science + ...

    E-Print Network [OSTI]

    Zanibbi, Richard

    DOUBLE MAJORS Imaging Science + ... Applied Mathematics Biomedical Sciences Computer Science Undergraduate Research Internships and Cooperative Education (Co-op) (optional) Study Abroad WHY IMAGING SCIENCE Science: BS, MS, PhD Color Science: MS, PhD BS + MS/PhD Combos HUMAN VISION BIO- MEDICAL ASTRO- PHYSICS

  12. FES Science Network Requirements

    E-Print Network [OSTI]

    Geddes, Cameron Guy Robinson

    FES Science Network Requirements Report of the Fusion Energy Sciences Network Requirements Workshop Conducted March 13 and 14, 2008 #12;FES Science Network Requirements Workshop Fusion Energy Sciences Program Office, DOE Office of Science Energy Sciences Network Gaithersburg, MD ­ March 13 and 14, 2008 ESnet

  13. Computer Science Degree options

    E-Print Network [OSTI]

    Brierley, Andrew

    82 Computer Science Degree options BSc (Single Honours Degree) Computer Science BSc (Joint Honours Degrees) Computer Science and one of: Economics Logic and Philosophy of Science Management Management Science MSci (Single Honours Degree) Computer Science Entrance Requirements (see also pages 164 - 205

  14. Mathematical methods for protein science

    SciTech Connect (OSTI)

    Hart, W.; Istrail, S.; Atkins, J. [Sandia National Labs., Albuquerque, NM (United States)

    1997-12-31T23:59:59.000Z

    Understanding the structure and function of proteins is a fundamental endeavor in molecular biology. Currently, over 100,000 protein sequences have been determined by experimental methods. The three dimensional structure of the protein determines its function, but there are currently less than 4,000 structures known to atomic resolution. Accordingly, techniques to predict protein structure from sequence have an important role in aiding the understanding of the Genome and the effects of mutations in genetic disease. The authors describe current efforts at Sandia to better understand the structure of proteins through rigorous mathematical analyses of simple lattice models. The efforts have focused on two aspects of protein science: mathematical structure prediction, and inverse protein folding.

  15. Genomic Sequence or Signature Tags (GSTs) from the Genome Group at Brookhaven National Laboratory (BNL)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Dunn, John J.; McCorkle, Sean R.; Praissman, Laura A.; Hind, Geoffrey; Van der Lelie, Daniel; Bahou, Wadie F.; Gnatenko, Dmitri V.; Krause, Maureen K.

    Genomic Signature Tags (GSTs) are the products of a method we have developed for identifying and quantitatively analyzing genomic DNAs. The DNA is initially fragmented with a type II restriction enzyme. An oligonucleotide adaptor containing a recognition site for MmeI, a type IIS restriction enzyme, is then used to release 21-bp tags from fixed positions in the DNA relative to the sites recognized by the fragmenting enzyme. These tags are PCR-amplified, purified, concatenated and then cloned and sequenced. The tag sequences and abundances are used to create a high resolution GST sequence profile of the genomic DNA. [Quoted from Genomic Signature Tags (GSTs): A System for Profiling Genomic DNA, Dunn, John J.; McCorkle, Sean R.; Praissman, Laura A.; Hind, Geoffrey; Van der Lelie, Daniel; Bahou, Wadie F.; Gnatenko, Dmitri V.; Krause, Maureen K., Revised 9/13/2002

  16. Genome sequence analysis of the model grass Brachypodium distachyon: insights into grass genome evolution

    SciTech Connect (OSTI)

    Schulman, Al

    2009-08-09T23:59:59.000Z

    Three subfamilies of grasses, the Erhardtoideae (rice), the Panicoideae (maize, sorghum, sugar cane and millet), and the Pooideae (wheat, barley and cool season forage grasses) provide the basis of human nutrition and are poised to become major sources of renewable energy. Here we describe the complete genome sequence of the wild grass Brachypodium distachyon (Brachypodium), the first member of the Pooideae subfamily to be completely sequenced. Comparison of the Brachypodium, rice and sorghum genomes reveals a precise sequence- based history of genome evolution across a broad diversity of the grass family and identifies nested insertions of whole chromosomes into centromeric regions as a predominant mechanism driving chromosome evolution in the grasses. The relatively compact genome of Brachypodium is maintained by a balance of retroelement replication and loss. The complete genome sequence of Brachypodium, coupled to its exceptional promise as a model system for grass research, will support the development of new energy and food crops

  17. A Complete Neandertal Mitochondrial Genome Sequence Determined

    E-Print Network [OSTI]

    Good, Jeffrey M.

    Rothberg Institute for Childhood Diseases, Guilford, CT 06437, USA 7Croatian Academy of Sciences and Arts, Zrinski trg 11, HR-10000 Zagreb, Croatia 8Croatian Academy of Sciences and Arts, Institute for Quaternary

  18. Microbial Protein-Protein Interactions (MiPPI) Data from the Genomics: GTL Center for Molecular and Cellular Systems (CMCS)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The Genomic Science Center for Molecular and Cellular Systems (CMCS), established in 2002, seeks to identify and characterize the complete set of protein complexes within a cell to provide a mechanistic basis for the understanding of biochemical functions. The CMCS is anchored at ORNL and PNNL. CMCS initially focused on the identification and characterization of protein complexes in two microbial systems,Rhodopseudomonas palustris (R. palustris) and Shewanella oneidensis (S. oneidensis). These two organisms have also been the focus of major DOE Genomic Science/Microbial Cell Program (MCP) projects. To develop an approach for identifying the diverse types of complexes present in microbial organisms, CMCS incorporates a number of molecular biology, microbiology, analytical and computational tools in an integrated pipeline.

  19. Science Highlights

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLas ConchasPassiveSubmitted for USMaterialstheterahertzonExploreStudies Science

  20. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    242 Political Science The School of Social Sciences Degrees Offered: BA, MA, PhD Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science,including American politics and comparative politics

  1. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    217 Political Science The School of Social Sciences Chair T. Clifton Morgan Professors John S.D. Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American and comparative politics

  2. POLITICAL SCIENCE Political science is the study

    E-Print Network [OSTI]

    POLITICAL SCIENCE Political science is the study of governments, public policies, and political behavior. Political science uses both humanistic perspectives and scientific skills to examine the United States and all countries and regions of the world. Students enrolled in Political Science courses explore

  3. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    1 Political Science The School of Social Sciences Degrees Offered: BA, MA, PhD Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American politics and comparative politics

  4. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    264 Political Science The School of Social Sciences Degrees Offered: BA, MA, PhD Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American politics and comparative politics

  5. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    235 Political Science The School of Social Sciences Chair T. Clifton Morgan Professors John S.D. Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American and comparative politics

  6. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    Political Science The School of Social Sciences Degrees Offered: BA, MA, PhD Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American politics and comparative politics

  7. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    242 Political Science The School of Social Sciences Chair T. Clifton Morgan Professors Earl Black.D. Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American and comparative politics

  8. Political Science The School of Social Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    253 Political Science The School of Social Sciences Degrees Offered: BA, MA, PhD Students majoring in political science are encouraged to achieve both a broad understanding of the field and a specialized knowledge of one or more aspects of political science, including American politics and comparative politics

  9. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    College of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection December 2009 January 2010 Volume VIII (5) Moving from the Superficial the superficial level so that the result is the formation of deep relationships, caring, compassion, justice, love

  10. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    College of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection April 2011 Volume IX (4) The end of the spring semester is quickly approaching accreditation review. Similarly, the Environmental and Occupational Health program also had a very positive

  11. College of Health Sciences Health Sciences Connection

    E-Print Network [OSTI]

    Barrash, Warren

    today. In politics, in education, in health care, in society in general we are so turned inwardCollege of Health Sciences Health Sciences Connection 1 Dean's Message College of Health Sciences Health Sciences Connection April/May 2010 Volume VIII (8) WOW! Spring semester of 2010 is almost

  12. [Faculty of Science Information and Computing Sciences

    E-Print Network [OSTI]

    Löh, Andres

    [Faculty of Science Information and Computing Sciences] Generic diff Andres Löh joint work with Eelco Lempsink and Sean Leather Dept. of Information and Computing Sciences, Utrecht University IFIP WG 2.1 meeting #64, Weltenburg, April 2, 2009 #12;[Faculty of Science Information and Computing

  13. College of Veterinary Medicine and Biomedical Sciences

    E-Print Network [OSTI]

    , protein, lipid and carbohydrate biochemistry, medicinal chemistry, enzymology, metabolomics, genomics

  14. Physical mapping of complex genomes

    DOE Patents [OSTI]

    Evans, Glen A. (Encinitas, CA)

    1993-01-01T23:59:59.000Z

    Method for simultaneous identification of overlapping cosmid clones among multiple cosmid clones and the use of the method for mapping complex genomes are provided. A library of cosmid clones that contains the DNA to be mapped is constructed and arranged in a manner such that individual clones can be identified and replicas of the arranged clones prepared. In preferred embodiments, the clones are arranged in a two dimensional matrix. In such embodiments, the cosmid clones in a row are pooled, mixed probes complementary to the ends of the DNA inserts int he pooled clones are synthesized, hybridized to a first replica of the library. Hybridizing clones, which include the pooled row, are identified. A second portion of clones is prepared by pooling cosmid clones that correspond to a column in the matrix. The second pool thereby includes one clone from the first portion pooled clones. This common clone is located on the replica at the intersection of the column and row. Mixed probes complementary to the ends of the DNA inserts in the second pooled portion of clones are prepared and hybridized to a second replica of the library. The hybridization pattern on the first and second replicas of the library are compared and cross-hybridizing clones, other than the clones in the pooled column and row, that hybridize to identical clones in the first and second replicas are identified. These clones necessarily include DNA inserts that overlap with the DNA insert int he common clone located at the intersection of the pooled row and pooled column. The DNA in the entire library may be mapped by pooling the clones in each of the rows and columns of the matrix, preparing mixed end-specific probes and hybridizing the probes from each row or column to a replica of the library. Since all clones in the library are located at the intersection of a column and a row, the overlapping clones for all clones in the library may be identified and a physical map constructed. In other preferred embodiments, the cosmid clones are arranged in a three dimensional matrix, pooled and compared in threes according to intersecting planes of the three dimensional matrix. Arrangements corresponding to geometries of higher dimensions may also be prepared and used to simultaneously identify overlapping clones in highly complex libraries with relatively few hybridization reactions.

  15. Physical mapping of complex genomes

    DOE Patents [OSTI]

    Evans, G.A.

    1993-06-15T23:59:59.000Z

    A method for the simultaneous identification of overlapping cosmid clones among multiple cosmid clones and the use of the method for mapping complex genomes are provided. A library of cosmid clones that contains the DNA to be mapped is constructed and arranged in a manner such that individual clones can be identified and replicas of the arranged clones prepared. In preferred embodiments, the clones are arranged in a two dimensional matrix. In such embodiments, the cosmid clones in a row are pooled, mixed probes complementary to the ends of the DNA inserts in the pooled clones are synthesized, hybridized to a first replica of the library. Hybridizing clones, which include the pooled row, are identified. A second portion of clones is prepared by pooling cosmid clones that correspond to a column in the matrix. The second pool thereby includes one clone from the first portion pooled clones. This common clone is located on the replica at the intersection of the column and row. Mixed probes complementary to the ends of the DNA inserts in the second pooled portion of clones are prepared and hybridized to a second replica of the library. The hybridization pattern on the first and second replicas of the library are compared and cross-hybridizing clones, other than the clones in the pooled column and row, that hybridize to identical clones in the first and second replicas are identified. These clones necessarily include DNA inserts that overlap with the DNA insert in the common clone located at the intersection of the pooled row and pooled column. The DNA in the entire library may be mapped by pooling the clones in each of the rows and columns of the matrix, preparing mixed end-specific probes and hybridizing the probes from each row or column to a replica of the library. Since all clones in the library are located at the intersection of a column and a row, the overlapping clones for all clones in the library may be identified and a physical map constructed.

  16. Genomes to life project quarterly report June 2004.

    SciTech Connect (OSTI)

    Heffelfinger, Grant S.

    2005-01-01T23:59:59.000Z

    This SAND report provides the technical progress through June 2004 of the Sandia-led project, ''Carbon Sequestration in Synechococcus Sp.: From Molecular Machines to Hierarchical Modeling'', funded by the DOE Office of Science Genomes to Life Program. Understanding, predicting, and perhaps manipulating carbon fixation in the oceans has long been a major focus of biological oceanography and has more recently been of interest to a broader audience of scientists and policy makers. It is clear that the oceanic sinks and sources of CO{sub 2} are important terms in the global environmental response to anthropogenic atmospheric inputs of CO{sub 2} and that oceanic microorganisms play a key role in this response. However, the relationship between this global phenomenon and the biochemical mechanisms of carbon fixation in these microorganisms is poorly understood. In this project, we will investigate the carbon sequestration behavior of Synechococcus Sp., an abundant marine cyanobacteria known to be important to environmental responses to carbon dioxide levels, through experimental and computational methods. This project is a combined experimental and computational effort with emphasis on developing and applying new computational tools and methods. Our experimental effort will provide the biology and data to drive the computational efforts and include significant investment in developing new experimental methods for uncovering protein partners, characterizing protein complexes, identifying new binding domains. We will also develop and apply new data measurement and statistical methods for analyzing microarray experiments. Computational tools will be essential to our efforts to discover and characterize the function of the molecular machines of Synechococcus. To this end, molecular simulation methods will be coupled with knowledge discovery from diverse biological data sets for high-throughput discovery and characterization of protein-protein complexes. In addition, we will develop a set of novel capabilities for inference of regulatory pathways in microbial genomes across multiple sources of information through the integration of computational and experimental technologies. These capabilities will be applied to Synechococcus regulatory pathways to characterize their interaction map and identify component proteins in these pathways. We will also investigate methods for combining experimental and computational results with visualization and natural language tools to accelerate discovery of regulatory pathways. The ultimate goal of this effort is develop and apply new experimental and computational methods needed to generate a new level of understanding of how the Synechococcus genome affects carbon fixation at the global scale. Anticipated experimental and computational methods will provide ever-increasing insight about the individual elements and steps in the carbon fixation process, however relating an organism's genome to its cellular response in the presence of varying environments will require systems biology approaches. Thus a primary goal for this effort is to integrate the genomic data generated from experiments and lower level simulations with data from the existing body of literature into a whole cell model. We plan to accomplish this by developing and applying a set of tools for capturing the carbon fixation behavior of complex of Synechococcus at different levels of resolution. Finally, the explosion of data being produced by high-throughput experiments requires data analysis and models which are more computationally complex, more heterogeneous, and require coupling to ever increasing amounts of experimentally obtained data in varying formats. These challenges are unprecedented in high performance scientific computing and necessitate the development of a companion computational infrastructure to support this effort.

  17. Multiple Whole Genome Alignments Without a Reference Organism

    SciTech Connect (OSTI)

    Dubchak, Inna; Poliakov, Alexander; Kislyuk, Andrey; Brudno, Michael

    2009-01-16T23:59:59.000Z

    Multiple sequence alignments have become one of the most commonly used resources in genomics research. Most algorithms for multiple alignment of whole genomes rely either on a reference genome, against which all of the other sequences are laid out, or require a one-to-one mapping between the nucleotides of the genomes, preventing the alignment of recently duplicated regions. Both approaches have drawbacks for whole-genome comparisons. In this paper we present a novel symmetric alignment algorithm. The resulting alignments not only represent all of the genomes equally well, but also include all relevant duplications that occurred since the divergence from the last common ancestor. Our algorithm, implemented as a part of the VISTA Genome Pipeline (VGP), was used to align seven vertebrate and sixDrosophila genomes. The resulting whole-genome alignments demonstrate a higher sensitivity and specificity than the pairwise alignments previously available through the VGP and have higher exon alignment accuracy than comparable public whole-genome alignments. Of the multiple alignment methods tested, ours performed the best at aligning genes from multigene families?perhaps the most challenging test for whole-genome alignments. Our whole-genome multiple alignments are available through the VISTA Browser at http://genome.lbl.gov/vista/index.shtml.

  18. Sequencing and comparing whole mitochondrial genomes ofanimals

    SciTech Connect (OSTI)

    Boore, Jeffrey L.; Macey, J. Robert; Medina, Monica

    2005-04-22T23:59:59.000Z

    Comparing complete animal mitochondrial genome sequences is becoming increasingly common for phylogenetic reconstruction and as a model for genome evolution. Not only are they much more informative than shorter sequences of individual genes for inferring evolutionary relatedness, but these data also provide sets of genome-level characters, such as the relative arrangements of genes, that can be especially powerful. We describe here the protocols commonly used for physically isolating mtDNA, for amplifying these by PCR or RCA, for cloning,sequencing, assembly, validation, and gene annotation, and for comparing both sequences and gene arrangements. On several topics, we offer general observations based on our experiences to date with determining and comparing complete mtDNA sequences.

  19. Expanding Science and Energy Literacy with America's Science...

    Broader source: Energy.gov (indexed) [DOE]

    Expanding Science and Energy Literacy with America's Science and Technology Centers Expanding Science and Energy Literacy with America's Science and Technology Centers October 20,...

  20. Bringing large-scale multiple genome analysis one step closer: ScalaBLAST and beyond

    SciTech Connect (OSTI)

    Oehmen, Christopher S.; Sofia, Heidi J.; Baxter, Douglas; Szeto, Ernest; Hugenholtz, Philip; Kyrpides, Nikos; Markowitz, Victor; Straatsma, Tjerk P.

    2007-06-01T23:59:59.000Z

    Genome sequence comparisons of exponentially growing data sets form the foundation for the comparative analysis tools provided by community biological data resources such as the Integrated Microbial Genome (IMG) system at the Joint Genome Institute (JGI). We present an example of how ScalaBLAST, a high-throughput sequence analysis program harnesses increasingly critical high-performance computing to perform sequence analysis which is a critical component of maintaining a state-of-the-art sequence data repository. The Integrated Microbial Genomes (IMG) system1 is a data management and analysis platform for microbial genomes hosted at the JGI. IMG contains both draft and complete JGI genomes integrated with other publicly available microbial genomes of all three domains of life. IMG provides tools and viewers for interactive analysis of genomes, genes and functions, individually or in a comparative context. Most of these tools are based on pre-computed pairwise sequence similarities involving millions of genes. These computations are becoming prohibitively time consuming with the rapid increase in the number of newly sequenced genomes incorporated into IMG and the need to refresh regularly the content of IMG in order to reflect changes in the annotations of existing genomes. Thus, building IMG 2.0 (released on December 1st 2006) entailed reloading from NCBI's RefSeq all the genomes in the previous version of IMG (IMG 1.6, as of September 1st, 2006) together with 1,541 new public microbial,viral and eukaryal genomes, bringing the total of IMG genomes to 2,301. A critical part of building IMG 2.0 involved using PNNL ScalaBLAST software for computing pairwise similarities for over 2.2 million genes in under 26 hours on 1,000 processors, thus illustrating the impact that new generation bioinformatics tools are poised to make in biology. The BLAST algorithm2, 3 is a familiar bioinformatics application for computing sequence similarity, and has become a workhorse in large-scale genomics projects. The rapid growth of genome resources such as IMG cannot be sustained without more powerful tools such as ScalaBLAST that use more effectively large scale computing resources to perform the core BLAST calculations. ScalaBLAST is a high performance computing algorithm designed to give high throughput BLAST results on high-end supercomputers. Other parallel sequence comparison applications have been developed4-6. However problems with scaling generally prevent these applications from being used for very large searches. ScalaBLAST7 is the first BLAST application to be both highly scaleable against the size of the database as well as the number of computer processors on high-end hardware and on commodity clusters. ScalaBLAST achieves high throughput by parsing a large collection of query sequences into independent subgroups. These smaller tasks are assigned to independent process groups. Efficient scaling is achieved by (transparently to the user) sharing only one copy of the target database across all processors using the Global Array toolkit 8, 9, which provides software implementation of shared memory interface. ScalaBLAST was initially deployed on the 1,960 processor MPP2 cluster in the Wiliam R. Wiley Environmental Molecular Sciences Laboratory at Pacific Northwest National Laboratory, and has since been ported to a variety of linux-based clusters and shared memory architectures, including SGI Altix, AMD opteron, and Intel Xeon-based clusters. Future targets include IBM BlueGene, Cray, and SGI Altix XE architectures. The importance of performing high-throughput calculations rapidly lies in the rate of growth of sequence data. For a genome sequencing center to provide multiple-genome comparison capabilities, it must keep pace with exponentially growing collection of protein data, both from its own genomes, and from the public genome information as well. As sequence data continues to grow exponentially, this challenge will only increase with time. Solving the BLAST throughput challenge for centralized data resources like IMG has the poten

  1. MicrobesOnline: an integrated portal for comparative and functional genomics

    E-Print Network [OSTI]

    Dehal, Paramvir S.

    2010-01-01T23:59:59.000Z

    the US Department of Energy Genomics: GTL program (DE-AC02-Web site for comparative genomics. Genome Res, 15, 1015-comparative and functional genomics Paramvir S. Dehal 1,2* ,

  2. Bioinformatician position available Integrative Genomics of Ageing Group, University of Liverpool

    E-Print Network [OSTI]

    Bioinformatician position available Integrative Genomics of Ageing Group, University of Liverpool A bioinformatician position is available in the Integrative Genomics of Ageing Group at the University of Liverpool) systems biology, functional genomics, network analysis, and genome evolution. Applicants should have

  3. Evaluation And Application Of The Three A's Of Genomics: Assembly, Alignment, Annotation.

    E-Print Network [OSTI]

    Earl, Dent A.

    2014-01-01T23:59:59.000Z

    genome assembly. BMC Genomics, 10:180. [Locke et al. , 2011]of the three As of Genomics: Assembly, Alignment,among vertebrates. BMC Genomics, 11:21. [Blakesley et al. ,

  4. MicrobesOnline: An Integrated Portal For Comparative Functional Genomics (R-018)

    E-Print Network [OSTI]

    Huang, Y. Wayne

    2014-01-01T23:59:59.000Z

    andEnvironmentalResearch, Genomics:GTL Program throughComparative Functional Genomics (R-018) Y. Wayne Huang 1,2 ,genomeusingcomparativegenomicsandsequence motif

  5. Genome Engineering with TAL Effector Nucleases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: Vegetation ProposedUsingFun with Big Sky Learning Fun withGenepoolCrystals. |GenericGenomeGenome

  6. Genomic Data and Annotation from the SEED

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Fonstein, Michael; Kogan, Yakov; Osterman, Andrei; Overbeek, Ross; Vonstein, Veronika The Fellowship for Interpretation of Genomes (FIG)

    The SEED Project has been extended to support metagenomic samples and concomitant analytical tools. Moreover, the number of genomes being introduced into SEED is growing very rapidly. Building a framework to support this growth while providing highly accurate annotations is centrally important to SEED. The projects subsystem-based annotation strategy has become the technological foundation for addressing these challenges.(copied from Appendix 7 of Systems Biology Knowledgebase for a New Era in Biology, A Genomics:GTL Report from the May 2008 Workshop, DOE/SC-0113, Grequrick, S; Fredrickson, J.K.; Stevens, R., Pub March 1, 2009.)

  7. GenePING: secure, scalable management of personal genomic data

    E-Print Network [OSTI]

    Adida, Ben

    Background: Patient genomic data are rapidly becoming part of clinical decision making. Within a few years, full genome expression profiling and genotyping will be affordable enough to perform on every individual. The ...

  8. Initial sequencing and comparative analysis of the mouse genome

    SciTech Connect (OSTI)

    Waterston, Robert H.; Lindblad-Toh, Kerstin; Birney, Ewan; Rogers, Jane; Abril, Josep F.; Agarwal, Pankaj; Agarwala, Richa; Ainscough, Rachel; Alexandersson, Marina; An, Peter; Antonarakis, Stylianos E.; Attwood, John; Baertsch, Robert; Bailey, Jonathon; Barlow, Karen; Beck, Stephan; Berry, Eric; Birren, Bruce; Bloom, Toby; Bork, Peer; Botcherby, Marc; Bray, Nicolas; Brent, Michael R.; Brown, Daniel G.; Brown, Stephen D.; Bult, Carol; Burton, John; Butler, Jonathan; Campbell, Robert D.; Carninci, Piero; Cawley, Simon; Chiaromonte, Francesca; Chinwalla, Asif T.; Church, Deanna M.; Clamp, Michele; Clee, Christopher; Collins, Francis S.; Cook, Lisa L.; Copley, Richard R.; Coulson, Alan; Couronne, Olivier; Cuff, James; Curwen, Val; Cutts, Tim; Daly, Mark; David, Robert; Davies, Joy; Delehaunty, Kimberly D.; Deri, Justin; Dermitzakis, Emmanouil T.; Dewey, Colin; Dickens, Nicholas J.; Diekhans, Mark; Dodge, Sheila; Dubchak, Inna; Dunn, Diane M.; Eddy, Sean R.; Elnitski, Laura; Emes, Richard D.; Eswara, Pallavi; Eyras, Eduardo; Felsenfeld, Adam; Fewell, Ginger A.; Flicek, Paul; Foley, Karen; Frankel, Wayne N.; Fulton, Lucinda A.; Fulton, Robert S.; Furey, Terrence S.; Gage, Diane; Gibbs, Richard A.; Glusman, Gustavo; Gnerre, Sante; Goldman, Nick; Goodstadt, Leo; Grafham, Darren; Graves, Tina A.; Green, Eric D.; Gregory, Simon; Guigo, Roderic; Guyer, Mark; Hardison, Ross C.; Haussler, David; Hayashizaki, Yoshihide; Hillier, LaDeana W.; Hinrichs, Angela; Hlavina, Wratko; Holzer, Timothy; Hsu, Fan; Hua, Axin; Hubbard, Tim; Hunt, Adrienne; Jackson, Ian; Jaffe, David B.; Johnson, L. Steven; Jones, Matthew; Jones, Thomas A.; Joy, Ann; Kamal, Michael; Karlsson, Elinor K.; Karolchik, Donna; Kasprzyk, Arkadiusz; Kawai, Jun; Keibler, Evan; Kells, Cristyn; Kent, W. James; Kirby, Andrew; Kolbe, Diana L.; Korf, Ian; Kucherlapati, Raju S.; Kulbokas III, Edward J.; Kulp, David; Landers, Tom; Leger, J.P.; Leonard, Steven; Letunic, Ivica; Levine, Rosie; et al.

    2002-12-15T23:59:59.000Z

    The sequence of the mouse genome is a key informational tool for understanding the contents of the human genome and a key experimental tool for biomedical research. Here, we report the results of an international collaboration to produce a high-quality draft sequence of the mouse genome. We also present an initial comparative analysis of the mouse and human genomes, describing some of the insights that can be gleaned from the two sequences. We discuss topics including the analysis of the evolutionary forces shaping the size, structure and sequence of the genomes; the conservation of large-scale synteny across most of the genomes; the much lower extent of sequence orthology covering less than half of the genomes; the proportions of the genomes under selection; the number of protein-coding genes; the expansion of gene families related to reproduction and immunity; the evolution of proteins; and the identification of intraspecies polymorphism.

  9. Prescreening Illumina Data Results in High-Quality Genome Polishing

    SciTech Connect (OSTI)

    Han, Cliff [DOE Joint Genome Institute at Los Alamos National Laboratory

    2009-05-28T23:59:59.000Z

    Cliff Han of the DOE Joint Genome Institute at Los Alamos National Laboratory, talks about modifying their bacterial genome sequencing process to accommodate new sequencing technologies at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

  10. Use of Optical Mapping in Bacterial Genome Finishing

    SciTech Connect (OSTI)

    Kumar, Dibyendu [University of Florida

    2010-06-03T23:59:59.000Z

    Dibyendu Kumar from the University of Florida discusses whole-genome optical mapping to help validate bacterial genome assemblies on June 3, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

  11. MycoCosm, an Integrated Fungal Genomics Resource

    SciTech Connect (OSTI)

    Shabalov, Igor; Grigoriev, Igor

    2012-03-16T23:59:59.000Z

    MycoCosm is a web-based interactive fungal genomics resource, which was first released in March 2010, in response to an urgent call from the fungal community for integration of all fungal genomes and analytical tools in one place (Pan-fungal data resources meeting, Feb 21-22, 2010, Alexandria, VA). MycoCosm integrates genomics data and analysis tools to navigate through over 100 fungal genomes sequenced at JGI and elsewhere. This resource allows users to explore fungal genomes in the context of both genome-centric analysis and comparative genomics, and promotes user community participation in data submission, annotation and analysis. MycoCosm has over 4500 unique visitors/month or 35000+ visitors/year as well as hundreds of registered users contributing their data and expertise to this resource. Its scalable architecture allows significant expansion of the data expected from JGI Fungal Genomics Program, its users, and integration with external resources used by fungal community.

  12. ?-RA: a parallel sparse index for genomic read alignment

    E-Print Network [OSTI]

    Kü lekci, M O?uzhan; Hon, Wing-Kai; Shah, Rahul; Vitter, Jeffrey Scott; Xu, Bojian

    2011-07-27T23:59:59.000Z

    Background Genomic read alignment involves mapping (exactly or approximately) short reads from a particular individual onto a pre-sequenced reference genome of the same species. Because all individuals of the same species ...

  13. average genome size: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ancestry in the nuclear genomes of plastid underscore the power of comparative genomics and, at the same time, reveal how little we know with certainty 15 An Upper Bound on...

  14. Novel phylogenetic approaches to problems in microbial genomics

    E-Print Network [OSTI]

    David, Lawrence A. (Lawrence Anthony)

    2010-01-01T23:59:59.000Z

    Present day microbial genomes are the handiwork of over 3 billion years of evolution. Comparisons between these genomes enable stepping backwards through past evolutionary events, and can be formalized using binary tree ...

  15. The Human Genome Initiative of the Department of Energy

    SciTech Connect (OSTI)

    none,

    1988-01-01T23:59:59.000Z

    The structural characterization of genes and elucidation of their encoded functions have become a cornerstone of modern health research, biology and biotechnology. A genome program is an organized effort to locate and identify the functions of all the genes of an organism. Beginning with the DOE-sponsored, 1986 human genome workshop at Santa Fe, the value of broadly organized efforts supporting total genome characterization became a subject of intensive study. There is now national recognition that benefits will rapidly accrue from an effective scientific infrastructure for total genome research. In the US genome research is now receiving dedicated funds. Several other nations are implementing genome programs. Supportive infrastructure is being improved through both national and international cooperation. The Human Genome Initiative of the Department of Energy (DOE) is a focused program of Resource and Technology Development, with objectives of speeding and bringing economies to the national human genome effort. This report relates the origins and progress of the Initiative. 34 refs.

  16. Volume Visualization of Multiple Alignment of Large Genomic DNA

    E-Print Network [OSTI]

    Utah, University of

    . Another approach to understanding genetic code is through comparison of genomes, or parts of genomes/conservation between positions (http://www.cryst.bbk.ac.uk/BCD/bcdgloss.html). Figure 1 shows an example of a multiple

  17. Error and Error Mitigation in Low-Coverage Genome Assemblies

    E-Print Network [OSTI]

    Hubisz, Melissa J.

    The recent release of twenty-two new genome sequences has dramatically increased the data available for mammalian comparative genomics, but twenty of these new sequences are currently limited to ~2 coverage. Here we examine ...

  18. Defining functional DNA elements in the human genome

    E-Print Network [OSTI]

    Kellis, Manolis

    With the completion of the human genome sequence, attention turned to identifying and annotating its functional DNA elements. As a complement to genetic and comparative genomics approaches, the Encyclopedia of DNA Elements ...

  19. Reference genome sequence of the model plant Setaria

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    segregation of nuclear genes in plants. Bot. Gaz. 147, 26.in the nuclear genome of Fragaria vesca. Plant Genome 2, 93Nuclear DNA isolation from Setaria. A single, highly inbred Yugu1 plant

  20. Identifying Recent Adaptations in Large-Scale Genomic Data

    E-Print Network [OSTI]

    Andersen, KristianG.

    Although several hundred regions of the human genome harbor signals of positive natural selection, few of the relevant adaptive traits and variants have been elucidated. Using full-genome sequence variation from the 1000 ...

  1. Comparative gene identification in mammalian, fly, and fungal genomes

    E-Print Network [OSTI]

    Lin, Michael F. (Michael Fong-Jay)

    2006-01-01T23:59:59.000Z

    An important step in genome interpretation is the accurate identification of protein-coding genes. One approach to gene identification is comparative analysis of the genomes of several related species, to find genes that ...

  2. Translating the cancer genome: Going beyond p values

    E-Print Network [OSTI]

    Chin, Lynda

    2008-01-01T23:59:59.000Z

    Mining the complex cancer (epi)genome for aberrations governing these processes has become a major activity

  3. Genomic islands predict functional adaptation in marine actinobacteria

    E-Print Network [OSTI]

    Penn, Kevin

    2010-01-01T23:59:59.000Z

    Ecological adaptations among bacterial populations have been linked to genomic islands, strain-specific regions of DNA that house

  4. Computing Sciences

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

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  5. ARM - Science

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  6. Science Briefs

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  7. Science Cafe

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

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  9. Science Highlights

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  10. Science Organizations

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  12. Science Highlights

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

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  1. Science Summary

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  10. Science Summary

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  11. Science Summary

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administrationcontroller systemsBi (2) Sr (2)Science Highlight Archives:2 MAY9, 2009tRNA » Links

  12. Isotope Science

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-SeriesFlickrinformation for andFuel-Efficient Engines |Iron is theIs YourScience

  13. Information Sciences

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  14. Materials Science

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  15. Biological Science

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  16. Science Digests

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  17. Science Events

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  18. Science Highlights

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  20. Cognitive Science (Humanities)

    E-Print Network [OSTI]

    Schnaufer, Achim

    Cognitive Science (Humanities) The University of Edinburgh College of Humanities and Social Science: Cognitive Science (Humanities) BSc Honours in: Cognitive Science Please see separate information sheets the disciplines that contribute to the study of human cognition. The Cognitive Science programme at Edinburgh

  1. FORENSIC SCIENCE The bachelor of science in forensic science at

    E-Print Network [OSTI]

    FORENSIC SCIENCE The bachelor of science in forensic science at Wichita State University is designed to meet an increasing demand for trained forensic scientists and technicians. No other university with this degree can be assigned to virtually any aspect of a forensic investigation with less pre-service training

  2. AIHS Translational Research Chair in Child Health Genomics

    E-Print Network [OSTI]

    Calgary, University of

    AIHS Translational Research Chair in Child Health Genomics The Department of Medical Genetics) invite applications for full-time academic position in Child Health Genomics. This position represents a major investment in genomic research and the successful applicant will join a program with a vision

  3. Reconciling Utility with Privacy in Genomics Mathias Humbert Erman Ayday

    E-Print Network [OSTI]

    Thévenaz, Jacques

    Reconciling Utility with Privacy in Genomics Mathias Humbert Erman Ayday Jean-Pierre Hubaux.telenti@chuv.ch ABSTRACT Direct-to-consumer genetics makes it possible for everyone to obtain their genome sequences. In order to contribute to medical research, a growing number of people publish their genomic data

  4. Using genomics to improve Bacillus anthracis diagnostics and

    E-Print Network [OSTI]

    Using genomics to improve Bacillus anthracis diagnostics and outbreak investigations Joakim ?gren;Using genomics to improve Bacillus anthracis diagnostics and outbreak investigations Abstract-generation sequencing (NGS) has revolutionized the way DNA is sequenced and the whole genome (i.e., all the DNA

  5. ORIGINAL ARTICLE Comparative genomics-guided loop-mediated isothermal

    E-Print Network [OSTI]

    Hsiang, Tom

    ORIGINAL ARTICLE Comparative genomics-guided loop-mediated isothermal amplification sequencing and analytical techniques, genomic sequence data of prok- aryotes are accumulating at a very rapid pace. As of October 2008, there are 873 complete and pub- lished genome sequences, as well as 2025

  6. Production Efficiency of Beef Cows through Mathematical Modeling and Genomics

    E-Print Network [OSTI]

    Production Efficiency of Beef Cows through Mathematical Modeling and Genomics For decades cows reside. With recent advances in genomics, the identification of intrinsic genetic factors Develop and evaluate the individual-based model· for production efficiency of beef cows using genomic

  7. Genomics and Transcriptomics of Plant Beneficial Serratia spp.

    E-Print Network [OSTI]

    Genomics and Transcriptomics of Plant Beneficial Serratia spp. Saraswoti Neupane Faculty of Natural. proteamaculans S4 (photo: S. Neupane) #12;Genomics and transcriptomics of plant beneficial Serratia spp. Abstract, and have potential as possible biocontrol agents in agriculture. This thesis provides the detailed genomic

  8. Feature selection in high dimensional regression problems for genomics

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Feature selection in high dimensional regression problems for genomics Julie Hamon1,2,3 , Clarisse, France julien.jacques@lifl.fr Abstract. In the context of genomic selection in animal breeding and "closed to real" datasets. Keywords: Feature selection, combinatorial optimization, regression, genomic. 1

  9. Potential of metabolomics as a functional genomics tool

    E-Print Network [OSTI]

    Wurtele, Eve Syrkin

    Potential of metabolomics as a functional genomics tool Raoul J. Bino1,2,3 , Robert D. Hall2 3 Centre for BioSystems Genomics, POB 98, 6700 AB Wageningen, The Netherlands 4 Max-Planck Institute Australian Centre for Plant Functional Genomics, School of Botany, University of Melbourne, Victoria 3010

  10. Genomics and computational molecular biology Douglas L Brutlag

    E-Print Network [OSTI]

    Brutlag, Doug

    340 Genomics and computational molecular biology Douglas L Brutlag There has been a dramatic increase in the number of completely sequenced bacterial genomes during the past two years as a result of the efforts both of public genome agencies and the pharmaceutical industry. The availability of completely

  11. Hindawi Publishing Corporation International Journal of Plant Genomics

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    Hindawi Publishing Corporation International Journal of Plant Genomics Volume 2008, Article ID 412875, 7 pages doi:10.1155/2008/412875 Research Article TreeGenes: A Forest Tree Genome Database Jill L are to (1) provide a comprehensive resource for forest tree genomics data to facilitate gene discovery

  12. Clique-detection Models in Computational Biochemistry and Genomics

    E-Print Network [OSTI]

    Butenko, Sergiy

    Clique-detection Models in Computational Biochemistry and Genomics S. Butenko and W. E. Wilhelm,wilhelm}@tamu.edu Abstract Many important problems arising in computational biochemistry and genomics have been formulated and genomic aspects of the problems as well as to the graph-theoretic aspects of the solution approaches. Each

  13. Genome Technology, No.56 October 2005 CROSSING OVER

    E-Print Network [OSTI]

    Ferrara, Katherine W.

    Genome Technology, No.56 October 2005 CROSSING OVER ACADEMIA OR INDUSTRY? WWW.GENOME-TECHNOLOGY importantly, if I try it out and don't like it, can I come back? Genome Technology interviewed a number-scientist types who chase down answers to impossibly huge (and sometimes useless) questions at the expense

  14. The Sunflower Genome and its Evolution (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema (OSTI)

    Rieseberg, Loren [University of British Columbia

    2013-01-15T23:59:59.000Z

    Loren Rieseberg from the University of British Columbia on "The Sunflower Genome and its Evolution" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  15. Genomics of Climate Resilience (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect (OSTI)

    Bermingham, Eldredge [STRI-Panama

    2013-03-27T23:59:59.000Z

    Eldredge Bermingham of the Smithsonian Tropical Research Institute-Panama on "Genomics of climate resilience" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  16. The Sunflower Genome and its Evolution (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect (OSTI)

    Rieseberg, Loren [University of British Columbia] [University of British Columbia

    2012-03-21T23:59:59.000Z

    Loren Rieseberg from the University of British Columbia on "The Sunflower Genome and its Evolution" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  17. Entering the Era of Mega-genomics ( JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema (OSTI)

    Schatz, Michael C [Cold Spring Harbor Laboratory

    2013-01-15T23:59:59.000Z

    Michael Schatz from Cold Spring Harbor Laboratory on "Entering the Era of Mega-genomics" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif.

  18. Entering the Era of Mega-genomics ( JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect (OSTI)

    Schatz, Michael C [Cold Spring Harbor Laboratory] [Cold Spring Harbor Laboratory

    2012-03-21T23:59:59.000Z

    Michael Schatz from Cold Spring Harbor Laboratory on "Entering the Era of Mega-genomics" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif.

  19. Using Genomics to Dissect Seed Development (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment Meeting)

    SciTech Connect (OSTI)

    Goldberg, Robert [UCLA] [UCLA

    2012-03-21T23:59:59.000Z

    Robert Goldberg of UCLA presents "Using Genomics to Dissect Seed Development" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  20. A rapid whole genome sequencing and analysis system supporting genomic epidemiology (7th Annual SFAF Meeting, 2012)

    ScienceCinema (OSTI)

    FitzGerald, Michael [Broad Institute

    2013-02-12T23:59:59.000Z

    Michael FitzGerald on "A rapid whole genome sequencing and analysis system supporting genomic epidemiology" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  1. Using Genomics to Dissect Seed Development (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment Meeting)

    ScienceCinema (OSTI)

    Goldberg, Robert [UCLA

    2013-01-22T23:59:59.000Z

    Robert Goldberg of UCLA presents "Using Genomics to Dissect Seed Development" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  2. POSTDOCTORAL OR RESEARCH ASSISTANT POSITIONS--Bioinformatics, comparative genomics, endosymbiosis and genome evolution

    E-Print Network [OSTI]

    Archibald, John

    of nuclear genome sequences from two unicellular algae (http://www.jgi.doe.gov/sequencing/why/CSP2007 are essential, as are strong written and oral communication abilities. The positions are available starting May

  3. Genome complexity reduction for genome-wide single nucleotide polymorphism analysis

    E-Print Network [OSTI]

    Jordan, Barbara M. (Barbara Marie), 1975-

    2002-01-01T23:59:59.000Z

    Millions of single nucleotide polymorphisms (SNPs) have been identified in the human genome, and more are cataloged every day. The challenge now is to use these SNPs to discover the genetic risk factors underlying common ...

  4. Genome Biology 2004, 5:R102 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    Brendel, Volker

    RNAs and other splicingrelated proteins, together with information on gene structure, alternative splicing, gene genes encoding splicing-related proteins were identified in the Arabidopsis genome by sequence. Plant RNA splicing mechanisms remain comparatively poorly understood, due in part to the lack

  5. Comparative Analysis of Genome Sequences with VISTA

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Dubchak, Inna

    VISTA is a comprehensive suite of programs and databases developed by and hosted at the Genomics Division of Lawrence Berkeley National Laboratory. They provide information and tools designed to facilitate comparative analysis of genomic sequences. Users have two ways to interact with the suite of applications at the VISTA portal. They can submit their own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species. A key menu option is the Enhancer Browser and Database at http://enhancer.lbl.gov/. The VISTA Enhancer Browser is a central resource for experimentally validated human noncoding fragments with gene enhancer activity as assessed in transgenic mice. Most of these noncoding elements were selected for testing based on their extreme conservation with other vertebrates. The results of this enhancer screen are provided through this publicly available website. The browser also features relevant results by external contributors and a large collection of additional genome-wide conserved noncoding elements which are candidate enhancer sequences. The LBL developers invite external groups to submit computational predictions of developmental enhancers. As of 10/19/2009 the database contains information on 1109 in vivo tested elements - 508 elements with enhancer activity.

  6. DOE Joint Genome Institute 2008 Progress Report

    E-Print Network [OSTI]

    Gilbert, David

    2009-01-01T23:59:59.000Z

    CSP), and requests from DOE Bioenergy Re- search Centers. In recognition of the programmatic importance of plantplant genomes sequenced by the 4. Foxtail Millet The second-largest CSPCSP), is an organism of tremendous economic and ecological importance and a key representative of the conifers, an ancient lineage of plants

  7. Gene conversion in the rice genome

    E-Print Network [OSTI]

    Xu, Shuqing; Clark, Terry; Zheng, Hongkun; Vang, SÃ ¸ ren; Li, Ruiqiang; Wong, Gane Ka-Shu; Wang, Jun; Zheng, Xiaoguang

    2008-02-25T23:59:59.000Z

    . Over 60% of the conversions we detected were between chromosomes. We found that the inter-chromosomal conversions distributed between chromosome 1 and 5, 2 and 6, and 3 and 5 are more frequent than genome average (Z-test, P < 0.05). The frequencies...

  8. Genome-level homology and phylogeny of Vibrionaceae (Gammaproteobacteria: Vibrionales) with three new complete genome sequences

    E-Print Network [OSTI]

    Dikow, R. B.; Smith, William Leo

    2013-04-11T23:59:59.000Z

    . Wachsmuth IK, Blake PA, Olsvik O: Vibrio cholerae and Cholera. Molecular to Global Perspectives. Washington: ASM Press; 1994. Dikow and Smith BMCMicrobiology 2013, 13:80 Page 13 of 13 http://www.biomedcentral.com/1471-2180/13/80 7. CDC: Vibrio vulnificus...Dikow and Smith BMCMicrobiology 2013, 13:80 http://www.biomedcentral.com/1471-2180/13/80 RESEARCH ARTICLE Open Access Genome-level homology and phylogeny of Vibrionaceae (Gammaproteobacteria: Vibrionales) with three new complete genome sequences...

  9. Computer Science | More Science | ORNL

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsruc DocumentationP-Series to User Group andCompositional Variation The ComputationalofScience and

  10. Nuclear Science | More Science | ORNL

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the ContributionsArms Control R&D ConsortiumNuclearSafeguards andScience SHARE

  11. Nuclear Sciences | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the ContributionsArms Control R&D ConsortiumNuclearSafeguards andScience

  12. Nuclear Sciences | More Science | ORNL

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the ContributionsArms Control R&D ConsortiumNuclearSafeguards andScienceNuclear

  13. NREL: Energy Sciences - Materials Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the Contributions and Achievements ofLiz Torres PhotoMaterials Science Learn about our

  14. The NCBI Eukaryotic Genome Annotation Process Enhancing the value of assembled genomes through annotation using a standardized pipeline

    E-Print Network [OSTI]

    Levin, Judith G.

    annotation using a standardized pipeline http://www.ncbi.nlm.nih.gov/genome/ National Center Pipeline | Last Update August 19, 2013 Overview The NCBI eukaryotic genome annotation pipeline provides alignment services, and the Map Viewer genome browser. The pipeline uses a modular framework

  15. E-Science Day

    E-Print Network [OSTI]

    Abad, Raquel

    2012-01-01T23:59:59.000Z

    on December 6, 2011, E-Science Day was a day-long event,regional librarians in e-science, and to expose regionalthe initiation of e-science support projects within their

  16. BES Science Network Requirements

    E-Print Network [OSTI]

    Dart, Eli

    2011-01-01T23:59:59.000Z

    the Directors of the Office of Science, Office of AdvancedOffice of Basic Energy Sciences. This is LBNL report LBNL-BES Science Network Requirements Report of the Basic Energy

  17. COMPUTER SCIENCE SAMPLE PROGRAM

    E-Print Network [OSTI]

    Gering, Jon C.

    COMPUTER SCIENCE SAMPLE PROGRAM (First Math Course MATH 198) This sample program suggests one way CS 181: Foundations of Computer Science II CS 180: Foundations of Computer Science I CS 191

  18. Computer Science Induction to

    E-Print Network [OSTI]

    Berger, Ulrich

    Computer Science Induction to Postgraduate Research Studies Ulrich Berger Head of Postgraduate Research Supervision Regulations Progression Regulations Computer Science Induction to Postgraduate Research Studies Ulrich Berger Head of Postgraduate Research Department of Computer Science Swansea

  19. E-Science Day

    E-Print Network [OSTI]

    Abad, Raquel

    2012-01-01T23:59:59.000Z

    initiation of e-science support projects within their ownapplications of e-science-related projects and initiatives.in future e-science planning. This project has been funded

  20. Communicating Evolution as Science

    E-Print Network [OSTI]

    Thanukos, Anastasia

    2010-01-01T23:59:59.000Z

    thuringiensis toxins. Science. 1992;258(5087):14515. MillerRT, Ruse M. But is it science? Amherst, NY: Prometheusto the philosophy of science: theory and reality. Chicago:

  1. History of Science Science and Empire

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    and Margaret Lock (Berkeley: University of California Press, 1993), 305- 29. Fanon, Frantz. "Medicine) Basalla, George. "The Spread of Western Science." Science 156, no. 3775 (1967): 611-22. Bocking, Stephen

  2. surface science | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    surface science surface science Leads No leads are available at this time. Nonlinear Photoemission Electron Micrographs of Plasmonic Nanoholes in Gold Thin Films. Abstract:...

  3. subsurface science | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    subsurface science subsurface science Leads No leads are available at this time. Competing retention pathways of uranium upon reaction with Fe(II). Abstract: Biogeochemical...

  4. INSTITUTE OF COMPUTER SCIENCE

    E-Print Network [OSTI]

    Institute of Computer Science, Academy of Sciences of the Czech Republic. Pod vodrenskou v 2, 182 07 Prague 8, Czech Republic. phone: (+420)266052083...

  5. INSTITUTE OF COMPUTER SCIENCE

    E-Print Network [OSTI]

    Institute of Computer Science, Academy of Sciences of the Czech Republic. Pod vodrenskou v 2, 182 07 Prague 8, Czech Republic. phone: (+4202) 6884244...

  6. Space Science and Applications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1 Space Science and Applications Applying world-class expertise in space sciences and associated technologies to detect and characterize national security threats Contacts Group...

  7. Applied Computer Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computing CCS Division Applied Computer Science Applied Computer Science Innovative co-design of applications, algorithms, and architectures in order to enable scientific...

  8. Information & Computer Sciences Mathematics

    E-Print Network [OSTI]

    Sciences Mathematics Microbiology Physics & Astronomy www.hawaii.edu/natsci2014 NAT SCI #12;Table 8 Department of Information & Computer Sciences 9 Department of Mathematics

  9. Science Research Library

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Founded in 1952, the library has extensive resources in nuclear physics, chemistry, heat transfer and fluid flow, materials science, energy, and computer science. The...

  10. Applied Computer Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science and Innovation Computing CCS Division CCS-7 Applied Computer Science Innovative co-design of applications, algorithms, and architectures in order to enable...

  11. Publications | Neutron Science | ORNL

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    Publications SHARE Publications The Neutron Science publications system contains peer-reviewed publications based on research conducted at ORNL's Neutron Science facilities or...

  12. Metal Hydrides - Science Needs

    Broader source: Energy.gov (indexed) [DOE]

    with traditions in metal hydride research Metal and Ceramic Sciences Condensed Matter Physics Materials Chemistry Chemical and Biological Sciences Located on campus of Tier...

  13. Master of Science Physikalische

    E-Print Network [OSTI]

    Berlin,Technische Universität

    Master of Science Physikalische Ingenieurwissenschaft Engineering Science Beratungsstellen EPFL· Aufbau des Studiums Der Masterstudiengang Physikalische Ingenieurwissenschaft Berufsfelder Zugangsvoraussetzungen Verlauf des Studiums Der Masterstudiengang Physikalische Ingenieurwissen- schaft bereitet aufgrund

  14. Bradbury Science Museum

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    February Newsletter now availableFind out what's happening @ the Bradbury Science Museum in our latest monthly newsletter. Plan your visit entrance to Bradbury Science Museum...

  15. OPTICAL SCIENCE & ENGINEERINGOPTICAL SCIENCE & ENGINEERINGOPTICAL SCIENCE & ENGINEERINGOPTICAL SCIENCE & ENGINEERING University of New Mexico

    E-Print Network [OSTI]

    New Mexico, University of

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  17. Standards in Genomic Sciences (2011) 4:252-256 DOI:10.4056/sigs.1724282 The Genomic Standards Consortium

    E-Print Network [OSTI]

    Eddy, Sean

    Institute, Yale University, New Haven, CT, USA 11 Department of Chemistry, Bowling Green State University, Bowling Green, OH, USA 12 Department of Mathematics and Statistics, Bowling Green State University, Bowling Green, OH, USA 13 Howard Hughes Medical Institute, Boulder, CO, USA 14 Department of Biology

  18. Standards in Genomic Sciences (2013) 9:495-504 DOI:10.4056/sigs.4708537 The Genomic Standards Consortium

    E-Print Network [OSTI]

    Bae, Jin-Woo

    ], wastewater [4-6], river sediments containing chromium [5], nematodes [7,8], food [1,9], potato plant-8T should help us to understand the molecular basis of adap- tation to a chromium

  19. Genomics:GTL Bioenergy Research Centers White Paper

    SciTech Connect (OSTI)

    Mansfield, Betty Kay [ORNL; Alton, Anita Jean [ORNL; Andrews, Shirley H [ORNL; Bownas, Jennifer Lynn [ORNL; Casey, Denise [ORNL; Martin, Sheryl A [ORNL; Mills, Marissa [ORNL; Nylander, Kim [ORNL; Wyrick, Judy M [ORNL; Drell, Dr. Daniel [Office of Science, Department of Energy; Weatherwax, Sharlene [U.S. Department of Energy; Carruthers, Julie [U.S. Department of Energy

    2006-08-01T23:59:59.000Z

    In his Advanced Energy Initiative announced in January 2006, President George W. Bush committed the nation to new efforts to develop alternative sources of energy to replace imported oil and fossil fuels. Developing cost-effective and energy-efficient methods of producing renewable alternative fuels such as cellulosic ethanol from biomass and solar-derived biofuels will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy production methods will not suffice. The Genomics:GTL Bioenergy Research Centers will be dedicated to fundamental research on microbe and plant systems with the goal of developing knowledge that will advance biotechnology-based strategies for biofuels production. The aim is to spur substantial progress toward cost-effective production of biologically based renewable energy sources. This document describes the rationale for the establishment of the centers and their objectives in light of the U.S. Department of Energy's mission and goals. Developing energy-efficient and cost-effective methods of producing alternative fuels such as cellulosic ethanol from biomass will require transformational breakthroughs in science and technology. Incremental improvements in current bioenergy-production methods will not suffice. The focus on microbes (for cellular mechanisms) and plants (for source biomass) fundamentally exploits capabilities well known to exist in the microbial world. Thus 'proof of concept' is not required, but considerable basic research into these capabilities remains an urgent priority. Several developments have converged in recent years to suggest that systems biology research into microbes and plants promises solutions that will overcome critical roadblocks on the path to cost-effective, large-scale production of cellulosic ethanol and other renewable energy from biomass. The ability to rapidly sequence the DNA of any organism is a critical part of these new capabilities, but it is only a first step. Other advances include the growing number of high-throughput techniques for protein production and characterization; a range of new instrumentation for observing proteins and other cell constituents; the rapid growth of commercially available reagents for protein production; a new generation of high-intensity light sources that provide precision imaging on the nanoscale and allow observation of molecular interactions in ultrafast time intervals; major advances in computational capability; and the continually increasing numbers of these instruments and technologies within the national laboratory infrastructure, at universities, and in private industry. All these developments expand our ability to elucidate mechanisms present in living cells, but much more remains to be done. The Centers are designed to accomplish GTL program objectives more rapidly, more effectively, and at reduced cost by concentrating appropriate technologies and scientific expertise, from genome sequence to an integrated systems understanding of the pathways and internal structures of microbes and plants most relevant to developing bioenergy compounds. The Centers will seek to understand the principles underlying the structural and functional design of selected microbial, plant, and molecular systems. This will be accomplished by building technological pathways linking the genome-determined components in an organism with bioenergy-relevant cellular systems that can be characterized sufficiently to generate realistic options for biofuel development. In addition, especially in addressing what are believed to be nearer-term approaches to renewable energy (e.g., producing cellulosic ethanol cost-effectively and energy-efficiently), the Center research team must understand in depth the current industrial-level roadblocks and bottlenecks (see section, GTL's Vision for Biological Energy Alternatives, below). For the Centers, and indeed the entire BER effort, to be successful, Center research must be integrated with individual investigator research, and coordination of activities,

  20. School of Mathematical & Computer Sciences Dept of Computer Science

    E-Print Network [OSTI]

    Painter, Kevin

    School of Mathematical & Computer Sciences Dept of Computer Science BSc Computer Systems Programme & Computer Sciences Dept of Computer Science BSc Computer Systems Programme Handbook 2014 Watt University .......................................................................................................6 School of Mathematical and Computer Sciences