National Library of Energy BETA

Sample records for black lung disability

  1. Delays in processing and adjudicating black lung claims. Hearing before a Subcommittee of the Committee on Government Operations, House of Representatives, Ninety-Ninth Congress, First Session, June 24, 1985

    SciTech Connect (OSTI)

    Not Available

    1986-01-01

    Representatives of coal miners and black lung claimants testified about the failure of government agencies to process claims in a fair and timely manner at a field hearing in Charleston, West Virginia before a joint congressional delegation. At issue were bureaucratic delays of up to seven years in administering the compensation promised to affected workers. Lawyers who handle black lung cases also have trouble receiving the guaranteed reimbursement. At the time of the hearing, West Virginia alone had over 3200 cases awaiting hearings and only 200 scheduled for hearings. Officials of the Department of Labor discussed the level of funding and staffing of the review board as they relate to the size of the backlog. Administrators complained that regulatory interpretations and attitudes work against the miners' interests. Letters, statements, and additional material submitted for the record follow the testimony of 12 witnesses.

  2. Advances in Lung Volume

    E-Print Network [OSTI]

    Jones, Michelle

    Advances in Lung Volume Reduction Surgery The Ohio University Medical Center Lung Volume Reduction LungVolumeReductionSurgery Spring 2010 © 2010 The Ohio State University Medical Center ­ 04 Consult Ohio State's #12;The Ohio State University Medical Center Lung Volume Reduction Surgery Patient

  3. Population segments with disabilities 

    E-Print Network [OSTI]

    Stough, Laura

    2013-01-01

    because only approximately 4% of older Americans live in nursing care (McGuire, et al, 2007). To further illustrate the concept of layered vulnerability, it is well understood that older adults are likely to “age-in-place” such that they are less likely..., both individuals with disabilities and elderly adults often evidence similar specific physical disabilities, such as mobility disabilities or sensory impairments. Both also experience socio-economic vulnerabilities, such as poverty, unemployment...

  4. AmericanLungAssociationStateofLungDiseaseinDiverseCommunities2010 55 Lung Cancer

    E-Print Network [OSTI]

    Kaski, Samuel

    AmericanLungAssociationStateofLungDiseaseinDiverseCommunities2010 55 Lung Cancer Lung cancer is the uncontrolled growth of abnormal cells in one or both of the lungs . While normal cells reproduce and develop into healthy lung tissue, these abnormal cells reproduce faster and never grow into normal lung tissue . Lumps

  5. American Disabilities Act

    Broader source: Energy.gov [DOE]

    The Americans with Disabilities Act prohibits private employers, state and local governments, employment agencies and labor unions from discriminating against qualified individuals with disabilities in job application procedures, hiring, firing, advancement, compensation, job training, and other terms, conditions, and privileges of employment.

  6. Disabilities and disaster 

    E-Print Network [OSTI]

    Stough, Laura

    2010-01-01

    stream_source_info Disabilities and disaster.pdf.txt stream_content_type text/plain stream_size 3 Content-Encoding ISO-8859-1 stream_name Disabilities and disaster.pdf.txt Content-Type text/plain; charset=ISO-8859-1 ...

  7. Frizzled-8 as a putative therapeutic target in human lung cancer

    SciTech Connect (OSTI)

    Wang, Hua-qing; Department of Medical Oncology, Tianjin Medical University Cancer Hospital, Tianjin 300060 ; Xu, Mei-lin; Ma, Jie; Zhang, Yi; Xie, Cong-hua

    2012-01-06

    Highlights: Black-Right-Pointing-Pointer Fzd-8 is over-expressed in human lung cancer. Black-Right-Pointing-Pointer shRNA knock-down of Fzd-8 inhibits proliferation and Wnt pathway in lung cancer cells. Black-Right-Pointing-Pointer shRNA knock-down of Fzd-8 suppresses tumor growth in vivo. Black-Right-Pointing-Pointer shRNA knock-down Fzd-8 sensitizes lung cancer cells to chemotherapy Taxotere. -- Abstract: Lung cancer is the leading cause of cancer related deaths worldwide. It is necessary to better understand the molecular mechanisms involved in lung cancer in order to develop more effective therapeutics for the treatment of this disease. Recent reports have shown that Wnt signaling pathway is important in a number of cancer types including lung cancer. However, the role of Frizzled-8 (Fzd-8), one of the Frizzled family of receptors for the Wnt ligands, in lung cancer still remains to be elucidated. Here in this study we showed that Fzd-8 was over-expressed in human lung cancer tissue samples and cell lines. To investigate the functional importance of the Fzd-8 over-expression in lung cancer, we used shRNA to knock down Fzd-8 mRNA in lung cancer cells expressing the gene. We observed that Fzd-8 shRNA inhibited cell proliferation along with decreased activity of Wnt pathway in vitro, and also significantly suppressed A549 xenograft model in vivo (p < 0.05). Furthermore, we found that knocking down Fzd-8 by shRNA sensitized the lung cancer cells to chemotherapy Taxotere. These data suggest that Fzd-8 is a putative therapeutic target for human lung cancer and over-expression of Fzd-8 may be important for aberrant Wnt activation in lung cancer.

  8. Ability - Not Disability: Wheelchairs. 

    E-Print Network [OSTI]

    Anonymous,

    1981-01-01

    The Texas A&M University System .Jf Texas Agricu~tural Extension Service Daniel C. Plannstiel . Director College Station ABILITY NOT DISABILITY . W'heelchairs 8-1254 '! y [Blank Page in Original Bulletin] .~ ... ABILITY - NOT DISABILITY...: WHEELCHAIRS For the homemaker in a wheelchair, the key to running a home well is to have an efficient and usable kitchen and laundry area. Not everyone can build a new kitchen, but alterations can make chores easier. Rearranging the Kitchen All counters...

  9. Ability - Not Disability: Clothing. 

    E-Print Network [OSTI]

    Anonymous,

    1981-01-01

    The Texas A&~ University Syst ~ Texas Agricu~tural Extension Service Daniel C. Pfannstiel . Director College Station BILITY NOT DISABILITY 610thing 8?1255 [Blank Page in Original Bulletin] ? 'I ~ ? ... ABILITY-NOT DISABILITY: CLOTHING... level, race, color, sex, religion or national origin. Cooperative Extension Work in Agriculture and Home Economics, The Texas A&M University System and the United States Department of Agriculture cooperating. Distributed in furtherance of the Acts...

  10. Lung Cancer James Nguyen

    E-Print Network [OSTI]

    Brutlag, Doug

    Lung Cancer James Nguyen Biochemistry 118Q Doug Brutlag A Case Study of Genetics and Environment #12;Lung Cancer · Leading cause of cancer for men and women in United States · Every year, about 164,000 new cases are diagnosed in the US, with an estimated 157,000 deaths. · Leading cause of cancer death

  11. IIT CDR Disability Housing Accommodations Request Form Page 1 of 3 DISABILITY HOUSING ACCOMMODATIONS REQUEST FORM

    E-Print Network [OSTI]

    Heller, Barbara

    IIT CDR ­ Disability Housing Accommodations Request Form Page 1 of 3 DISABILITY HOUSING's housing resources. Please refer to the Disability Housing Accommodations Procedures & Guidelines for the complete process for requesting disability-related housing accommodations, including deadlines. Students

  12. Disaster and disabilities 

    E-Print Network [OSTI]

    Stough, Laura

    2014-01-01

    when schools were closed and programs were reorganized (McAdams Ducy & Stough, 2011). Individuals with disabilities in the United States are entitled to equal access to emergency services, such as evacuation procedures and sheltering. The Stafford Act...; McAdams Ducy, & Stough, 2011) have doc- umented that teachers can provide effective emotional, as well as instrumental, support to students with disabili- ties during disasters. Similarly, employers who provide supported work environments need...

  13. QUESTIONS & ANSWERS ABOUT LUNG CANCER

    E-Print Network [OSTI]

    QUESTIONS & ANSWERS ABOUT LUNG CANCER Q: What are the early signs of lung cancer? How would I know I have it? A: Some of the early warning signs of lung cancer are: · A cough that doesn't go away what may be causing these symptoms. Q: How is lung cancer diagnosed? A: Your doctor may do one or more

  14. University of Wisconsin-Madison Academic Staff Disability Accommodation Policy

    E-Print Network [OSTI]

    Saffman, Mark

    Divisional Disability Representative (DDR). Each dean/director has appointed a DDR to respond to disability

  15. Americans with Disabilities Act Signed (1990)

    Broader source: Energy.gov [DOE]

    The Americans with Disabilities Act of 1990 (ADA) prohibits discrimination and ensures equal opportunity for persons with disabilities in employment, State and local government services, public...

  16. with Disabilities Act Requirements Workplace ADA Requirements...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Americans with Disabilities Act (ADA) is a federal civil rights law that prohibits discrimination in public places against individuals with disabilities. As an employer installing...

  17. Children with disabilities in disaster 

    E-Print Network [OSTI]

    Stough, Laura

    2012-01-01

    stream_source_info Children with disabilities in disaster.pdf.txt stream_content_type text/plain stream_size 2 Content-Encoding ISO-8859-1 stream_name Children with disabilities in disaster.pdf.txt Content-Type text/plain; charset...

  18. Lung pair phantom

    DOE Patents [OSTI]

    Olsen, P.C.; Gordon, N.R.; Simmons, K.L.

    1993-11-30

    The present invention is a material and method of making the material that exhibits improved radiation attenuation simulation of real lungs, i.e., an ``authentic lung tissue`` or ALT phantom. Specifically, the ALT phantom is a two-part polyurethane medium density foam mixed with calcium carbonate, potassium carbonate if needed for K-40 background, lanthanum nitrate, acetone, and a nitrate or chloride form of a radionuclide. This formulation is found to closely match chemical composition and linear attenuation of real lungs. The ALT phantom material is made according to established procedures but without adding foaming agents or preparing thixotropic concentrate and with a modification for ensuring uniformity of density of the ALT phantom that is necessary for accurate simulation. The modification is that the polyurethane chemicals are mixed at a low temperature prior to pouring the polyurethane mixture into the mold.

  19. Fluid blade disablement tool

    DOE Patents [OSTI]

    Jakaboski, Juan-Carlos (Albuquerque, NM); Hughs, Chance G. (Albuquerque, NM); Todd, Steven N. (Rio Rancho, NM)

    2012-01-10

    A fluid blade disablement (FBD) tool that forms both a focused fluid projectile that resembles a blade, which can provide precision penetration of a barrier wall, and a broad fluid projectile that functions substantially like a hammer, which can produce general disruption of structures behind the barrier wall. Embodiments of the FBD tool comprise a container capable of holding fluid, an explosive assembly which is positioned within the container and which comprises an explosive holder and explosive, and a means for detonating. The container has a concavity on the side adjacent to the exposed surface of the explosive. The position of the concavity relative to the explosive and its construction of materials with thicknesses that facilitate inversion and/or rupture of the concavity wall enable the formation of a sharp and coherent blade of fluid advancing ahead of the detonation gases.

  20. Early Lung Cancer Detection Program

    Broader source: Energy.gov [DOE]

    Since 2000, DOE has made screening for occupational lung cancer with low-dose helical computed tomography (CT) scans available to workers at high risk for lung cancer. Because former workers undertook essential activities to fulfill the Department's mission, many of them were at risk for lung cancer.

  1. Ability - Not Disability: Organizing Housework. 

    E-Print Network [OSTI]

    McCormack, Linda J.

    1981-01-01

    -------Th-eT -exas-A&M~ ----:8-1259 University System ~ Texas Agricu ~tura I Extension Service Daniel C Plannstiel . DIrector College Station ABILITY NOT DISABILITY Organizing Housework [Blank Page in Original Bulletin] ~. '!". ABILITY... - NOT DISABILITY: ORGANIZING HOUSEWORK Linda J. McCormack? Before organizing housework, think about Rudyard Kipling's poem, "I Keep Six Honest Service Men." "I keep six honest serving men (they taught me all I know) their names are What and Why and When...

  2. CHEST Supplement Screening for Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    e78S CHEST Supplement Screening for Lung Cancer DIAGNOSIS AND MANAGEMENT OF LUNG CANCER, 3RD ED individuals). 3.2.2. In patients at risk for developing lung cancer, screening for lung cancer with sputum are age 55 to 74 and who have smoked for Background: Lung cancer is by far the major cause of cancer

  3. Lung Transplantation for Advanced Bronchiectasis

    E-Print Network [OSTI]

    Turner, Monica G.

    Lung Transplantation for Advanced Bronchiectasis Don Hayes Jr., M.D., F.A.A.P., F.A.C.P., F.C.C.P.1 and Keith C. Meyer, M.D., M.S., F.A.C.P., F.C.C.P.2 ABSTRACT Lung transplant (LT) can be successfully performed on patients with advanced bronchiectatic lung disease with subsequent good posttransplant quality

  4. DEFENSA PERSONAL -GAU LUNG SAT FUNDAMENTACIN

    E-Print Network [OSTI]

    Escolano, Francisco

    DEFENSA PERSONAL - GAU LUNG SAT FUNDAMENTACIÓN El Gau Lung Sat es un programa de entrenamiento cuyo aprendizaje la innovadora metodología del Gau Lung Sat. Esta establece diferentes áreas de trabajo

  5. Del Black

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HAB Packet HanfordDOEDanielDe novo Design ofDefects LeadDel Black Del

  6. UNO Disability Services Prospective Learning Disability Release Student Packet

    E-Print Network [OSTI]

    Li, X. Rong

    YEARS OLD. The documentation provided must include information that diagnoses a learning disability (as of the following tests. Please check all tests that apply: ___ Weschler Adult Intelligence Scale-III ___ Kaufman Adolescent and Adult Intelligence ___ Stanford-Binet Intelligence Scale (5th ed.) Achievement - Must include

  7. Disability Resource Centre: Support and advice for disabled students

    E-Print Network [OSTI]

    Jackson, Sophie

    /mobility impairments and injuries (including wheelchair users, Upper Limb Disorder/RSI) n sensory impairments, schizophrenia, anxiety disorder) n long standing illnesses/health conditions (including cancer, chronic fatigue students ­ both from the government and from the University. These include: n Disabled Students' Allowances

  8. www.yalecancercenter.org Lung Cancer Screening

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Screening Guest Experts: Lynn Tanoue, MD Professor of Therapeutic Radiology and an expert in the use of radiation to treat lung cancers and cutaneous lymphomas Oncology Program. Dr. Detterbeck and I also co- direct the new Yale Lung Cancer and Lung Nodule Screening

  9. Superthreshold Behavior of Ultrasound-Induced Lung

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Superthreshold Behavior of Ultrasound-Induced Lung Hemorrhage in Adult Rats Role of Pulse of an earlier ultrasound-induced lung hemorrhage study (Ultrasound Med Biol 2003; 29:1625­1634) that estimated, at least for the lung. Key Words: duty factor; lung hemorrhage; pulsed ultrasound; pulse duration; pulse

  10. Automated segmentation of lungs with severe interstitial lung disease in CT

    E-Print Network [OSTI]

    Automated segmentation of lungs with severe interstitial lung disease in CT Jiahui Wang Department: Accurate segmentation of lungs with severe interstitial lung disease ILD in thoracic computed tomography CT developed in this study a texture analysis-based method for accurate segmentation of lungs with severe ILD

  11. (Dis)ability and (dis)aster 

    E-Print Network [OSTI]

    Stough, Laura; Kelman, Ilan

    2015-01-01

    and Pothier, 2006; Oliver, 1986, 1996). Others argue that conceptualizing disability as completely social in nature overlooks or minimizes the corporeal experiences and physical sensations of people with 9781137485991_02_c01.indd 5 disabilities (see... and Disasters 31(3): 384–402. Van Willigen, M., T. Edwards, B. Edwards, and S. Hessee. 2002. Riding out the storm: Experiences of the physically disabled during Hurricanes Bonnie, Dennis, and Floyd. Natural Hazards Review 3(3): 98–106. Wisner, B., P...

  12. Supermassive Black Holes

    E-Print Network [OSTI]

    Laura Ferrarese; David Merritt

    2002-06-13

    After a brief historical introduction, we summarize current efforts and accomplishments in the study of supermassive black holes.

  13. Black Pine Engineering

    Office of Energy Efficiency and Renewable Energy (EERE)

    Black Pine Engineering is commercializing a disruptive technology in the turbomachinery industry. Using a patented woven composite construction, Black Pine Engineering can make turbomachines (turbines, compressors) that are cheaper and lighter than competing technologies. Using this technology, Black Pine Engineering will sell turbo-compressors which solve the problem of wasted steam in geothermal power plants.

  14. Edinburgh Research Explorer Lung Microbiota Changes Associated with Chronic

    E-Print Network [OSTI]

    Millar, Andrew J.

    Edinburgh Research Explorer Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact of Intravenous Colistimethate Sodium Citation for published version, 'Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact

  15. Magnetized static black Saturn

    E-Print Network [OSTI]

    Stoytcho S. Yazadjiev

    2008-02-06

    We construct a new static solution to the 5D Einstein-Maxwell equations describing a static black hole surrounded by a non-rotating dipole black ring. The configuration is kept in equilibrium by an external magnetic field interacting with the dipole charge of the black ring. The properties of the black Saturn-like configuration are studied and the basic physical quantities are calculated. The solution demonstrates 2-fold continuous non-uniqueness of the 5D magnetized static neutral black objects for fixed total mass and Melvin background.

  16. Comprehensive molecular profiling of lung adenocarcinoma

    E-Print Network [OSTI]

    Lander, Eric S.

    Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, ...

  17. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : What You Need To Know About High on lowering cholesterol is available from the National Heart, Lung, and Blood Institute (NHLBI) Web site

  18. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Coronary Heart Disease C oronary is available from the National Heart, Lung, and Blood Institute (NHLBI) Web site at www.nhlbi.nih.gov (under

  19. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Physical Activity and Your Heart benefits. It can strengthen your heart and improve lung func- tion, and it may help prevent certain types

  20. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Atherosclerosis A therosclerosis, Lung, and Blood Institute (NHLBI) Web site at www.nhlbi.nih.gov (under Health Information

  1. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Facts About Healthy Weight Why indicator of your risk for a variety of diseases. To check your BMI, use the National Heart, Lung, and Blood

  2. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Healthy Sleep S leep is not just information on healthy sleep and sleep disorders is available from the National Heart, Lung, and Blood

  3. LungCAD: A Clinically Approved, Machine Learning System for Lung Cancer Detection

    E-Print Network [OSTI]

    Chandy, John A.

    LungCAD: A Clinically Approved, Machine Learning System for Lung Cancer Detection R Bharat Rao Street, New York, NY 10016 ABSTRACT We present LungCAD, a computer aided diagnosis (CAD) system system be tested in a clini- cal trial. We describe the clinical trial in which LungCAD was tested

  4. Biomarker for Lung and Inflammatory Diseases

    E-Print Network [OSTI]

    Heydari, Payam

    Biomarker for Lung and Inflammatory Diseases Tech ID: 23381 / UC Case 2012-660-0 BACKGROUND and clinical research. We describe herein a novel biomarker and method of detecting interstitial lung disease have discovered that patients with interstitial lung and intestinal inflammatory diseases, for example

  5. www.yalecancercenter.org Lung Cancer Awareness

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Awareness Month Update Guest Expert: Frank Detterbeck, MD take a look at the prevention and treatment of lung cancer with Dr. Frank Detterbeck, Professor I want to start out with a question about cigarette smoking and lung cancer. Obviously

  6. www.yalecancercenter.org Lung Cancer Awareness

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Awareness Month Update 2008 Guest Expert: Frank Detterbeck, MD reach the end of lung cancer awareness month, Ed and Ken welcome the Directors of the Yale Cancer Center of thoracic surgery at Yale and Dr. Tanoue is a Professor of pulmonary medicine. Tanoue Unfortunately, lung

  7. www.yalecancercenter.org Understanding Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Understanding Lung Cancer Guest Expert: Daniel Morgensztern, MD www of radiation to treat lung cancer and cutaneous lymphomas. If you would like to join the conversation, you can at the Yale School of Medicine and he specializes in the treatment and care of patients with lung cancer. Here

  8. Superthreshold Behavior of Ultrasound-Induced Lung

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Superthreshold Behavior of Ultrasound-Induced Lung Hemorrhage in Adult Rats Role of Pulse and reevaluate the ultra- sound-induced lung hemorrhage findings of a previous 5 × 3 factorial design study, 250, and 500 Hz) and exposure duration (ED; 5, 10, and 20 s) on ultrasound-induced lung hemorrhage

  9. What Lung Cancer Patients Need to Know

    E-Print Network [OSTI]

    Kaski, Samuel

    What Lung Cancer Patients Need to Know About Bone Health A Publication of The Bone and Cancer Foundation #12;Contents THIS PUBLICATION PROVIDES IMPORTANT INFORMATION ABOUT THE RELATIONSHIP BETWEEN LUNG CANCER AND BONE HEALTH. HOW BONE WORKS (PAGE 2). WHAT LUNG CANCER CAN DO TO BONE (PAGE 2). TREATING BONE

  10. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Bandettini, Peter A.

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Asthma A sthma is a chronic (longterm) lung dis ease that inflames and narrows the air ways. This makes the airways swollen and very, the muscles around them tighten. This causes the airways to nar row, and less air flows to your lungs

  11. Clinical and experimental pathology of lung cancer

    SciTech Connect (OSTI)

    McVie, J.G.; Bakker, W.; Wagenaar, S.C.; Carney, D.

    1986-01-01

    This book contains 17 selections. Some of the titles are: Flow cytometric DNA analysis in the study of small cell carcinoma of the lung; Mechanisms of oncogenesis; Adhesion mechanisms in liver metastasis; Current concepts in the therapy of small cell lung cancer; Application of monoclonal antibodies in imaging and therapy; and Clinical applications of the biologic properties of small cell lung cancer.

  12. The branching programme of mouse lung development

    E-Print Network [OSTI]

    Krasnow, Mark A.

    ARTICLES The branching programme of mouse lung development Ross J. Metzger1 {, Ophir D. Klein2 {, Gail R. Martin2 & Mark A. Krasnow1 Mammalian lungs are branched networks containing thousands by three geometrically simple local modes of branching used in three different orders throughout the lung

  13. Bicycling Black Rings

    E-Print Network [OSTI]

    Henriette Elvang; Maria J. Rodriguez

    2008-01-25

    We present detailed physics analyses of two different 4+1-dimensional asymptotically flat vacuum black hole solutions with spin in two independent planes: the doubly spinning black ring and the bicycling black ring system ("bi-rings"). The latter is a new solution describing two concentric orthogonal rotating black rings which we construct using the inverse scattering technique. We focus particularly on extremal zero-temperature limits of the solutions. We construct the phase diagram of currently known zero-temperature vacuum black hole solutions with a single event horizon, and discuss the non-uniqueness introduced by more exotic black hole configurations such as bi-rings and multi-ring saturns.

  14. Bicycling Black Rings

    E-Print Network [OSTI]

    Elvang, Henriette

    2008-01-01

    We present detailed physics analyses of two different 4+1-dimensional asymptotically flat vacuum black hole solutions with spin in two independent planes: the doubly spinning black ring and the bicycling black ring system ("bi-rings"). The latter is a new solution describing two concentric orthogonal rotating black rings which we construct using the inverse scattering technique. We focus particularly on extremal zero-temperature limits of the solutions. Such limits exist for both types of solutions; for the bi-rings it is obtained when the two rings drag each other to extremality through the effect of gravitational frame-dragging. We construct the phase diagram of currently known zero-temperature vacuum black hole solutions with a single event horizon, and discuss the non-uniqueness introduced by more exotic black hole configurations such as bi-rings and multi-ring saturns.

  15. BLACK HISTORY MONTH

    Broader source: Energy.gov [DOE]

    Black History Month is an annual celebration of achievements by black Americans and a time for recognizing the central role of African Americans in U.S. history. The event grew out of “Negro History Week,” created by historian Carter G. Woodson and other prominent African Americans. Other countries around the world, including Canada and the United Kingdom, also devote a month to celebrating black history.

  16. Accreting Black Holes

    E-Print Network [OSTI]

    Begelman, Mitchell C

    2014-01-01

    I outline the theory of accretion onto black holes, and its application to observed phenomena such as X-ray binaries, active galactic nuclei, tidal disruption events, and gamma-ray bursts. The dynamics as well as radiative signatures of black hole accretion depend on interactions between the relatively simple black-hole spacetime and complex radiation, plasma and magnetohydrodynamical processes in the surrounding gas. I will show how transient accretion processes could provide clues to these interactions. Larger global magnetohydrodynamic simulations as well as simulations incorporating plasma microphysics and full radiation hydrodynamics will be needed to unravel some of the current mysteries of black hole accretion.

  17. Trajectories of Happiness Following Acquired Disability 

    E-Print Network [OSTI]

    McCord, Carly Elizabeth

    2013-07-09

    Current deficits in the rehabilitation psychology literature involving longitudinal studies investigating positive outcomes following acquired disabilities have deserved research attention. In the current study, data on happiness as an enduring...

  18. Golden Field Office Disability Awareness Month Event

    Broader source: Energy.gov [DOE]

    Come join us for a Disability Awareness Month program on Monday, October 29, 2012 in Bldg. 17, 4th floor, from 10:00-11:00 am.   We will have a couple  of performers from a Theatre group named...

  19. Rotating Hairy Black Holes

    E-Print Network [OSTI]

    B. Kleihaus; J. Kunz

    2000-12-20

    We construct stationary black holes in SU(2) Einstein-Yang-Mills theory, which carry angular momentum and electric charge. Possessing non-trivial non-abelian magnetic fields outside their regular event horizon, they represent non-perturbative rotating hairy black holes.

  20. "Hybrid" Black Holes

    E-Print Network [OSTI]

    Valeri P. Frolov; Andrei V. Frolov

    2014-12-30

    We discuss a solution of the Einstein equations, obtained by gluing the external Kerr metric and the internal Weyl metric, describing an axisymmetric static vacuum distorted black hole. These metrics are glued at the null surfaces representing their horizons. For this purpose we use the formalism of massive thin null shells. The corresponding solution is called a "hybrid" black hole. The massive null shell has an angular momentum which is the origin of the rotation of the external Kerr spacetime. At the same time, the shell distorts the geometry inside the horizon. The inner geometry of the "hybrid" black hole coincides with the geometry of the interior of a non-rotating Weyl-distorted black hole. Properties of the "hybrid" black holes are briefly discussed.

  1. Thursday, April 10, 2008 A Fuller Picture of Your Lungs

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Thursday, April 10, 2008 A Fuller Picture of Your Lungs A cheap MRI machine images lung function poor pictures of the lungs, which are full of air, and gives an incomplete picture of lung functions a cheap MRI machine that uses a weak magnetic field to image critical aspects of lung physiology

  2. Comprehensive genomic characterization of squamous cell lung cancers

    E-Print Network [OSTI]

    Lander, Eric S.

    Lung squamous cell carcinoma is a common type of lung cancer, causing approximately 400,000 deaths per year worldwide. Genomic alterations in squamous cell lung cancers have not been comprehensively characterized, and no ...

  3. Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

    E-Print Network [OSTI]

    Lander, Eric S.

    Lung adenocarcinoma, the most common subtype of non-small cell lung cancer, is responsible for more than 500,000 deaths per year worldwide. Here, we report exome and genome sequences of 183 lung adenocarcinoma tumor/normal ...

  4. Biomechanics of the Lung 1 HUMAN RESPIRATORY MECHANICS, part 1

    E-Print Network [OSTI]

    Prestwich, Ken

    Biomechanics of the Lung 1 HUMAN RESPIRATORY MECHANICS, part 1: THE BIOMECHANICS OF THE LUNG1 Summary: We begin a detailed study of ventilation and then examine the static forces that exist in lungs at different volumes

  5. PURDUE UNIVERSITY BLACK CULTURAL CENTER

    E-Print Network [OSTI]

    Pittendrigh, Barry

    traveled to Detroit, Michigan to study our fall research theme, " Black Detroit: The History, Movement

  6. Black Holes and Galaxy Evolution

    E-Print Network [OSTI]

    David Merritt

    1999-10-29

    Supermassive binary black holes and their influence on the structure and evolution of galaxies is reviewed.

  7. 30-Day Temporary Disabled Parking Permit Guidelines Description

    E-Print Network [OSTI]

    Ravikumar, B.

    or out of state Department of Motor Vehicles Disability Placard, DP License plate, or blue SSU 30-Day dispensers located throughout the campus. 4. Vehicles displaying a valid DMV disabled placard, plate or SSU

  8. CIGNA Study Uncovers Relationship of Disabilities to Total Benefits Costs

    Broader source: Energy.gov [DOE]

    The findings of a new study reveal an interesting trend. Integrating disability programs with health care programs can potentially lower employers' total benefits costs and help disabled employees get back to work sooner and stay at work.

  9. Behavioral Assessment of Occupational Skills of Learning Disabled Adolescents

    E-Print Network [OSTI]

    Mathews, R. Mark; Whang, Paula L.; Fawcett, Stephen B.

    1980-01-01

    This study, using direct observation and measurement techniques, analyzed the differences in occupational skills among learning disabled youths and their non-learning disabled peers . The results showed low levels of ...

  10. Diesel Exhaust Dispersion in a Phospholipid Lung Surfactant ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Exhaust Dispersion in a Phospholipid Lung Surfactant Diesel Exhaust Dispersion in a Phospholipid Lung Surfactant 2005 Diesel Engine Emissions Reduction (DEER) Conference...

  11. Software Architecture Decomposition Using Attributes Chung-Horng Lung

    E-Print Network [OSTI]

    Lung, Chung-Horng

    1 Software Architecture Decomposition Using Attributes Chung-Horng Lung Xia Xu Department and Eppinger [29] in other engineering disciplines. Inspired by Alexander, Andreu [2] and Lung,

  12. Automatic Lung Vessel Segmentation via Stacked Multiscale Feature Learning

    E-Print Network [OSTI]

    Toronto, University of

    Automatic Lung Vessel Segmentation via Stacked Multiscale Feature Learning Ryan Kiros, Karteek We introduce a representation learning approach to segmenting vessels in the lungs. Our algorithm

  13. A poroelastic model of the lung

    E-Print Network [OSTI]

    Berger, Lorenz; Burrowes, Kelly; Grau, Vicente; Tavener, Simon; Bordas, Rafel

    2014-01-01

    This work is motivated by the modelling of ventilation and deformation in the lung for understanding the biomechanics of respiratory diseases. The main contribution is the derivation and implementation of a lung model that tightly couples a poroelastic model of lung parenchyma to an airway fluid network. The poroelastic model approximates the porous structure of lung parenchyma using a continuum model that allows us to naturally model changes in physiology by spatially varying material parameters, whilst conserving mass and momentum within the tissue. The proposed model will also take advantage of realistic deformation boundary conditions obtained from image registration, to drive the simulation. A finite element method is presented to discretize the equations in a monolithic way to ensure convergence of the nonlinear problem. To demonstrate the coupling between the poroelastic medium and the network flow model numerical simulations on a realistic lung geometry are presented. These numerical simulations are a...

  14. Decloaking disability : images of disability and technology in science fiction media

    E-Print Network [OSTI]

    Verlager, Alicia

    2006-01-01

    This work examines how images of disability are used to frame cultural narratives regarding technology. As advances in biotechnology ensure that more people will be living with technological prosthetics against and beneath ...

  15. www.yalecancercenter.org Lung Cancer Awareness 2009

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Lung Cancer Awareness 2009 Guest Expert: Thomas Lynch, Jr., MD Director of lung cancer. Chu What got you interested in focusing your career on the treatment of lung cancer? Lynch I actually got into lung cancer sort of by serendipity. I wish I could tell you that it was a well

  16. www.yalecancercenter.org A Survivor's Perspective: Lung

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org A Survivor's Perspective: Lung Cancer Guest Expert: Janet Brown www lung cancers and cutaneous lymphomas. If you would like to join the conversation, you can contact adenocarcinoma lung cancer. It started in my right lung and spread to 3 spots on my spine and to the pons area

  17. Study for Advanced Lung Cancer Patients Guest Expert

    E-Print Network [OSTI]

    O'Hern, Corey S.

    Study for Advanced Lung Cancer Patients Guest Expert: Roy S. Herbst, MD, PhD Ensign Professor message at 888-234-4YCC. This week you will hear a conversation about clinical trials for advanced lung of lung caner at Yale Cancer Center and Smilow Cancer Hospital? Herbst As you probably know, lung cancer

  18. www.yalecancercenter.org An Update on Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org An Update on Lung Cancer Guest Expert: Roy Decker, MD, PhD Assistant the detection and treatment of lung cancer with Dr. Scott Gettinger and Dr. Roy Decker. Chu Scott, let us start off by telling our listeners what lung cancer is and how common it is. Gettinger Lung cancer

  19. AMERICAN THORACIC SOCIETY PATIENT HEALTH SERIES Lung Cancer Prevention

    E-Print Network [OSTI]

    Kaski, Samuel

    AMERICAN THORACIC SOCIETY PATIENT HEALTH SERIES Lung Cancer Prevention What are the chances that I will develop lung cancer? The #1 cause of lung cancer is exposure to tobacco smoke. Your chances increase others (second-hand smoke), the greater your chances of developing lung cancer. People who have never

  20. Immune Reactions of the Lung in Infection and Allergy

    E-Print Network [OSTI]

    Manstein, Dietmar J.

    Immune Reactions of the Lung in Infection and Allergy ¡ Interactions of microorganisms with cells of the lung ¡ Cells and mediators in immune reactions of the lung Sabine Ehrt, New York, USA Rees Kassen, Hannover Characterization of pulmonary host defense mechanisms in chronic lung disease 10.00 ­ 10.40 Albert

  1. Virtual Lung Project Animated Film Series The Challenge

    E-Print Network [OSTI]

    Whitton, Mary C.

    Virtual Lung Project Animated Film Series The Challenge This film series seeks to educate lung. Each video describes a process the lung undergoes to function properly. Through integration of 3D of the lung's functions and purposes. Because mucus flow and ciliary movement are groundbreaking research

  2. NHLBI Workshop Summaries Resident Cellular Components of the Human Lung

    E-Print Network [OSTI]

    Engelhardt, John F.

    NHLBI Workshop Summaries Resident Cellular Components of the Human Lung Current Knowledge and Goals, Maryland; 5 Lung Diseases, National Heart, Lung and Blood Institute, National Institutes of Health and Cell Biology, The University of Iowa, Iowa City, Iowa; 11 Developmental Lung Biology Research

  3. Lung, Artificial: Basic Principles and Current Applications William J. Federspiel

    E-Print Network [OSTI]

    Federspiel, William J.

    Lung, Artificial: Basic Principles and Current Applications William J. Federspiel Kristie A. Henchir University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A. INTRODUCTION Artificial lungs currently of the lung, which is to oxygenate the blood and remove carbon dioxide. Current artificial lungs are also

  4. GREIT: towards a consensus EIT algorithm for lung images

    E-Print Network [OSTI]

    Adler, Andy

    GREIT: towards a consensus EIT algorithm for lung images Andy Adler1 , John Arnold2 , Richard in the patient's lungs. However, most clinical and physiological research in lung EIT is done using older reconstruction algorithm for lung EIT, called GREIT (Graz consensus Reconstruc- tion algorithm for EIT

  5. Estimating Volumes of Simulated Lung Cancer Nodules David E. Gilsinn

    E-Print Network [OSTI]

    Gilsinn, David E.

    Estimating Volumes of Simulated Lung Cancer Nodules David E. Gilsinn Bruce R. Borchardt Amelia Tebbe§ July 15, 2009 Abstract Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. Computed to- mography (CT) shows promise in detecting lung cancers at earlier, more operable

  6. Collapsibility of Lung Volume by Paired Inspiratory and Expiratory CT

    E-Print Network [OSTI]

    Collapsibility of Lung Volume by Paired Inspiratory and Expiratory CT Scans: Correlations with Lung Function and Mean Lung Density Tsuneo Yamashiro, MD, Shin Matsuoka, MD, PhD, Brian J. Bartholmai, MD, Rau: To evaluate the relationship between measurements of lung volume (LV) on inspiratory/expiratory computed

  7. Numerical study of variable lung ventilation strategies

    E-Print Network [OSTI]

    Yadav, Reena; Hiremath, Kirankumar; Bagler, Ganesh

    2015-01-01

    Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths. While it may seem intuitive that lungs may benefit from unvarying and stable ventilation pressure strategy, recently it has been reported that variable lung ventilation is advantageous. In this study, we analyze the mean tidal volume in response to different `variable ventilation pressure' strategies. We found that uniformly distributed variability in pressure gives the best tidal volume as compared to that of normal, scale- free, log normal and linear distributions.

  8. Black Holes In Astronomy Black Holes In Astronomy

    E-Print Network [OSTI]

    Wagner, Stephan

    Black Hole horizon static limit ergosphere radiation magnetic fields jet jet #12;Black-hole accretion with a central bulge. #12;Click to edit Master text styles Second level Third level Fourth level Fifth level Jets and lobes of Cygnus A Carilli et al. Supermassive black holes are the most powerful engines in the Universe

  9. The renaissance of black phosphorus

    E-Print Network [OSTI]

    Ling, Xi

    One hundred years after its first successful synthesis in the bulk form in 1914, black phosphorus (black P) was recently rediscovered from the perspective of a 2D layered material, attracting tremendous interest from ...

  10. Lung Cancer . Author manuscript p16INK4A inactivation mechanisms in non-small-cell lung cancer patients

    E-Print Network [OSTI]

    Boyer, Edmond

    Lung Cancer . Author manuscript Page /1 10 p16INK4A inactivation mechanisms in non-small-cell lung occupational risk factor and that asbestos acts synergistically with tobacco smoking to induce lung cancer. Although some somatic gene alterations in lung cancer have been linked to tobacco smoke, few data

  11. 82 SESSION 9. LUNGS II Using EIT to determine the role of gestational age on lung volume

    E-Print Network [OSTI]

    Adler, Andy

    82 SESSION 9. LUNGS II Using EIT to determine the role of gestational age on lung volume response calculated for preterm and extremely preterm lambs. 1 Introduction Lung aeration is the first process the newly born lung needs to achieve at birth if the transition from in-utero life is to be successful

  12. Black Holes And Their Entropy 

    E-Print Network [OSTI]

    Mei, Jianwei

    2010-10-12

    . . . . . . . . . 21 1. Solutions in Four Dimensions . . . . . . . . . . . . . . 22 2. Solutions in Higher Dimensions . . . . . . . . . . . . . 27 C. Black Hole Solutions in Supergravity Theories . . . . . . . 30 D. Plebanski-Demianski Type Solutions in d = 5... is to discuss the construction of new black hole solutions and the calculation of the black hole entropy. In Chapter II, we shall re- port some new black hole solutions that we have found during the past few years [21, 22, 23] and we will discuss some...

  13. The role of uPAR signaling in lung cancer Background and significance

    E-Print Network [OSTI]

    Gleeson, Joseph G.

    The role of uPAR signaling in lung cancer Background and significance Lung cancer is the leading of lung cancer ­ non-small-cell-lung cancer (about 85% of all lung cancer cases) and small- cell-lung cancer (about 15%) (Herbst et al., 2008). Small cell lung carcinoma (SCLC) is rapidly growing and often

  14. PCA-based lung motion model

    E-Print Network [OSTI]

    Li, Ruijiang; Jia, Xun; Zhao, Tianyu; Lamb, James; Yang, Deshan; Low, Daniel A; Jiang, Steve B

    2010-01-01

    Organ motion induced by respiration may cause clinically significant targeting errors and greatly degrade the effectiveness of conformal radiotherapy. It is therefore crucial to be able to model respiratory motion accurately. A recently proposed lung motion model based on principal component analysis (PCA) has been shown to be promising on a few patients. However, there is still a need to understand the underlying reason why it works. In this paper, we present a much deeper and detailed analysis of the PCA-based lung motion model. We provide the theoretical justification of the effectiveness of PCA in modeling lung motion. We also prove that under certain conditions, the PCA motion model is equivalent to 5D motion model, which is based on physiology and anatomy of the lung. The modeling power of PCA model was tested on clinical data and the average 3D error was found to be below 1 mm.

  15. Lung Nodule Detection in Screening Computed Tomography

    E-Print Network [OSTI]

    Gori, I; Cerello, P; Cheran, S C; De Nunzio, G; Fantacci, M E; Kasae, P; Masala, G L; Pérez-Martínez, A; Retico, A

    2007-01-01

    A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical Computed Tomography (CT) images with 1.25 mm slice thickness is presented. The basic modules of our lung-CAD system, a dot-enhancement filter for nodule candidate selection and a neural classifier for false-positive finding reduction, are described. The results obtained on the collected database of lung CT scans are discussed.

  16. Black Holes at Accelerators

    E-Print Network [OSTI]

    Bryan Webber

    2006-04-06

    In theories with large extra dimensions and TeV-scale gravity, black holes are copiously produced in particle collisions at energies well above the Planck scale. I briefly review some recent work on the phenomenology of this process, with emphasis on theoretical uncertainties and possible strategies for measuring the number of extra dimensions.

  17. Quantum black hole inflation

    E-Print Network [OSTI]

    M. B. Altaie

    2001-05-07

    In this paper we follow a new approach for particle creation by a localized strong gravitational field. The approach is based on a definition of the physical vacuum drawn from Heisenberg uncertainty principle. Using the fact that the gravitational field red-shifts the frequency modes of the vacuum, a condition on the minimum stregth of the gravitational field required to achieve real particle creation is derived. Application of this requirement on a Schwartzchid black hole resulted in deducing an upper limit on the region, outside the event horizon, where real particles can be created. Using this regional upper limit, and considering particle creation by black holes as a consequence of the Casimir effect, with the assumption that the created quanta are to be added to the initial energy, we deduce a natural power law for the development of the event horizon, and consequently a logarithmic law for the area spectrum of an inflating black hole. Application of the results on a cosmological model shows that if we start with a Planck-dimensional black hole, then through the process of particle creation we end up with a universe having the presently estimated critical density. Such a universe will be in a state of eternal inflation.

  18. Gasification of black liquor

    DOE Patents [OSTI]

    Kohl, Arthur L. (Woodland Hills, CA)

    1987-07-28

    A concentrated aqueous black liquor containing carbonaceous material and alkali metal sulfur compounds is treated in a gasifier vessel containing a relatively shallow molten salt pool at its bottom to form a combustible gas and a sulfide-rich melt. The gasifier vessel, which is preferably pressurized, has a black liquor drying zone at its upper part, a black liquor solids gasification zone located below the drying zone, and a molten salt sulfur reduction zone which comprises the molten salt pool. A first portion of an oxygen-containing gas is introduced into the gas space in the gasification zone immediatley above the molten salt pool. The remainder of the oxygen-containing gas is introduced into the molten salt pool in an amount sufficient to cause gasification of carbonaceous material entering the pool from the gasification zone but not sufficient to create oxidizing conditions in the pool. The total amount of the oxygen-containing gas introduced both above the pool and into the pool constitutes between 25 and 55% of the amount required for complete combustion of the black liquor feed. A combustible gas is withdrawn from an upper portion of the drying zone, and a melt in which the sulfur content is predominantly in the form of alkali metal sulfide is withdrawn from the molten salt sulfur reduction zone.

  19. Gasification of black liquor

    DOE Patents [OSTI]

    Kohl, A.L.

    1987-07-28

    A concentrated aqueous black liquor containing carbonaceous material and alkali metal sulfur compounds is treated in a gasifier vessel containing a relatively shallow molten salt pool at its bottom to form a combustible gas and a sulfide-rich melt. The gasifier vessel, which is preferably pressurized, has a black liquor drying zone at its upper part, a black liquor solids gasification zone located below the drying zone, and a molten salt sulfur reduction zone which comprises the molten salt pool. A first portion of an oxygen-containing gas is introduced into the gas space in the gasification zone immediately above the molten salt pool. The remainder of the oxygen-containing gas is introduced into the molten salt pool in an amount sufficient to cause gasification of carbonaceous material entering the pool from the gasification zone but not sufficient to create oxidizing conditions in the pool. The total amount of the oxygen-containing gas introduced both above the pool and into the pool constitutes between 25 and 55% of the amount required for complete combustion of the black liquor feed. A combustible gas is withdrawn from an upper portion of the drying zone, and a melt in which the sulfur content is predominantly in the form of alkali metal sulfide is withdrawn from the molten salt sulfur reduction zone. 2 figs.

  20. Disaster case management and individuals with disabilities 

    E-Print Network [OSTI]

    Stough, Laura

    2010-01-01

    may also incor- porate advocacy functions when case managers solicit agencies for services on the behalf of their clients (Compton, Galaway, & Cournoyer, 2005). A common objective of case management is to provide cost-effective services while... of disability-related knowledge. In addition, the interviewers used a critical incident technique (see Flanagan, 1954) for two of the interview questions. Critical inci- dent technique is used to interview participants within a workplace or organizational...

  1. Accommodations for Physical Disabilities | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar: DemonstrationProgram |toPhysical Disabilities

  2. Accommodations for Vision Disabilities | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels DataEnergy Webinar: DemonstrationProgram |toPhysical DisabilitiesVision

  3. Statistical Mechanics of Black Holes

    E-Print Network [OSTI]

    B. Harms; Y. Leblanc

    1992-05-11

    We analyze the statistical mechanics of a gas of neutral and charged black holes. The microcanonical ensemble is the only possible approach to this system, and the equilibrium configuration is the one for which most of the energy is carried by a single black hole. Schwarzschild black holes are found to obey the statistical bootstrap condition. In all cases, the microcanonical temperature is identical to the Hawking temperature of the most massive black hole in the gas. U(1) charges in general break the bootstrap property. The problems of black hole decay and of quantum coherence are also addressed.

  4. Identification of Astrophysical Black Holes

    E-Print Network [OSTI]

    Sandip K. Chakrabarti

    1998-03-19

    Black holes are by definition black, and therefore cannot be directly observed by using electromagnetic radiations. Convincing identification of black holes must necessarily depend on the identification of a very specially behaving matter and radiation which surround them. A major problem in this subject of black hole astrophysics is to quantify the behaviour of matter and radiation close to the horizon. In this review, the subject of black hole accretion and outflow is systematically developed. It is shown that both the stationary as well as the non-stationary properties of the observed spectra could be generally understood by these solutions. It is suggested that the solutions of radiative hydrodynamic equations may produce clear spectral signatures of black holes. Other circumstantial evidences of black holes, both in the galactic centers as well as in binary systems, are also presented.

  5. Radiation-induced lung injury

    SciTech Connect (OSTI)

    Rosiello, R.A.; Merrill, W.W. )

    1990-03-01

    The use of radiation therapy is limited by the occurrence of the potentially fatal clinical syndromes of radiation pneumonitis and fibrosis. Radiation pneumonitis usually becomes clinically apparent from 2 to 6 months after completion of radiation therapy. It is characterized by fever, cough, dyspnea, and alveolar infiltrates on chest roentgenogram and may be difficult to differentiate from infection or recurrent malignancy. The pathogenesis is uncertain, but appears to involve both direct lung tissue toxicity and an inflammatory response. The syndrome may resolve spontaneously or may progress to respiratory failure. Corticosteroids may be effective therapy if started early in the course of the disease. The time course for the development of radiation fibrosis is later than that for radiation pneumonitis. It is usually present by 1 year following irradiation, but may not become clinically apparent until 2 years after radiation therapy. It is characterized by the insidious onset of dyspnea on exertion. It most often is mild, but can progress to chronic respiratory failure. There is no known successful treatment for this condition. 51 references.

  6. Cognitive Disabilities and the Scope of Contractualist Justice

    E-Print Network [OSTI]

    Wong, Sophia Isako

    Cognitive Disabilities and the Scope of ContractualistJustice Sophia Isako Wong Long Island University John Rawls and other contract theorists have been criticized for excluding people with severe cognitive disabilities from the scope... of justice. I argue that this criticism is unfounded. I claim instead it would be irrational for parties to a Rawlsian social contract to exclude the interests of those with severe cognitive disabilities. Throughout his theory of justice, Rawls assumes...

  7. The Access Almanac: Ending the Abuse of Disabled Parking Placards

    E-Print Network [OSTI]

    Shoup, Donald

    2011-01-01

    Ending the Abuse of Disabled Parking Placards DONALD SHOUP Aattention for repeatedly parking illegally in spaceshandicappedfraud.org. Making curb parking accessible to

  8. Spinal cord gray matter atrophy correlates with multiple sclerosis disability

    E-Print Network [OSTI]

    2014-01-01

    Atrophy Correlates with Multiple Sclerosis Disability Regina1,5,6 Objective: In multiple sclerosis (MS), cerebral grayPMS 5 progressive multiple sclerosis; RMS 5 relapsing

  9. Black Hole Scan

    E-Print Network [OSTI]

    Juan Crisostomo; Ricardo Troncoso; Jorge Zanelli

    2000-09-22

    Gravitation theories selected by requiring that they have a unique anti-de Sitter vacuum with a fixed cosmological constant are studied. For a given dimension d, the Lagrangians under consideration are labeled by an integer k=1,2,...,[(d-1)/2]. Black holes for each d and k are found and are used to rank these theories. A minimum possible size for a localized electrically charged source is predicted in the whole set of theories, except General Relativity. It is found that the thermodynamic behavior falls into two classes: If d-2k=1, these solutions resemble the three dimensional black hole, otherwise, their behavior is similar to the Schwarzschild-AdS_4 geometry.

  10. Black holes at accelerators.

    E-Print Network [OSTI]

    Webber, Bryan R

    be presented and the effects of some of the uncertainties can be investigated. 3.1. Hawking Spectrum With the above assumptions, the spectrum of particles emitted during black hole decay takes the form dN dE ? ?E2 (eE/TH ? 1) T n+6H (8) where as usual... the trapped surface area [6, 7]. T030 02 4 6 8 10 0 0.2 0.4 0.6 0.8 1 1.2 n=0 n=1 n=2 n=6 E rS ?ˆ (0 ) ab s/ pi r2 S Figure 4: Grey-body factors for scalar emission on the brane from a (4 + n)D black hole. 0 2 4 6 8 10 0 0.2 0.4 0.6 0.8 1 1.2 n=0 n=1 n=2 n=6 E...

  11. Black Pine Circle Project

    SciTech Connect (OSTI)

    Mytko, Christine

    2014-03-31

    A group of seventh graders from Black Pine Circle school in Berkeley had the opportunity to experience the Advanced Light Source (ALS) as "users" via a collaborative field trip and proposal project. The project culminated with a field trip to the ALS for all seventh graders, which included a visit to the ALS data visualization room, a diffraction demonstration, a beamline tour, and informative sessions about x-rays and tomography presented by ALS scientists.

  12. Black Pine Circle Project

    ScienceCinema (OSTI)

    Mytko, Christine

    2014-09-15

    A group of seventh graders from Black Pine Circle school in Berkeley had the opportunity to experience the Advanced Light Source (ALS) as "users" via a collaborative field trip and proposal project. The project culminated with a field trip to the ALS for all seventh graders, which included a visit to the ALS data visualization room, a diffraction demonstration, a beamline tour, and informative sessions about x-rays and tomography presented by ALS scientists.

  13. Black Hole Demographics

    E-Print Network [OSTI]

    Laura Ferrarese

    2002-03-04

    The purpose of this contribution is to review the current status of black hole demographics in light of recent advances in the study of high redshift QSOs (section 2), local AGNs (section 3) and local quiescent galaxies (section 4). I will then outline the prospects for future progress (section 5), and discuss what I believe will be the challenges for the years to come [ABRIDGED].

  14. Student Disability Services 240 O'Leary Library , 61 Wilder Street Fl-2

    E-Print Network [OSTI]

    Massachusetts at Lowell, University of

    Student Disability Services 240 O'Leary Library , 61 Wilder Street Fl-2 Lowell, Massachusetts 01854 Disability Services 240 O'Leary Library, 61 Wilder Street Lowell, MA 01854 Disability@uml.edu Phone: (978

  15. A Model for Conducting Research with Learning Disabled Adolescents and Young Adults

    E-Print Network [OSTI]

    Meyen, Edward L.; Schiefelbusch, Richard L.; Deshler, Donald D.; Alley, Gordon R.; Schumaker, Jean B.; Clark, Frances L.

    1980-01-01

    Issues from the field of learning disabilities and the field of education in general which impact the learning disabled individual are discussed as they relate to research with learning disabled adolescents and young adults ...

  16. Role of Spirituality and Religion in Family Quality of Life for Families of Children with Disabilities

    E-Print Network [OSTI]

    Poston, Denise J.; Turnbull, Ann P.

    2004-01-01

    with a disability, eight individuals with a disability, family members of children without a disability, service providers, and administrators. Data were collected in urban and rural settings to elicit participants’ understanding of domains of family...

  17. Rsf-1 is overexpressed in non-small cell lung cancers and regulates cyclinD1 expression and ERK activity

    SciTech Connect (OSTI)

    Li, Qingchang; Dong, Qianze [Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, Liaoning (China)] [Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, Liaoning (China); Wang, Enhua, E-mail: wangenhuacmu@hotmail.com [Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, Liaoning (China)] [Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, Liaoning (China)

    2012-03-30

    Highlights: Black-Right-Pointing-Pointer Rsf-1 expression is elevated in non-small cell lung cancers. Black-Right-Pointing-Pointer Rsf-1 depletion inhibits proliferation and increased apoptosis in lung cancer cells. Black-Right-Pointing-Pointer Rsf-1 depletion decreases the level of cyclinD1 and phosphor-ERK expression. -- Abstract: Rsf-1 (HBXAP) was recently reported to be overexpressed in various cancers and associated with the malignant behavior of cancer cells. However, the expression of Rsf-1 in primary lung cancer and its biological roles in non-small cell lung cancer (NSCLC) have not been reported. The molecular mechanism of Rsf-1 in cancer aggressiveness remains ambiguous. In the present study, we analyzed the expression pattern of Rsf-1 in NSCLC tissues and found that Rsf-1 was overexpressed at both the mRNA and protein levels. There was a significant association between Rsf-1 overexpression and TNM stage (p = 0.0220) and poor differentiation (p = 0.0013). Furthermore, knockdown of Rsf-1 expression in H1299 and H460 cells with high endogenous Rsf-1 expression resulted in a decrease of colony formation ability and inhibition of cell cycle progression. Rsf-1 knockdown also induced apoptosis in these cell lines. Further analysis showed that Rsf-1 knockdown decreased cyclin D1 expression and phospho-ERK levels. In conclusion, Rsf-1 is overexpressed in NSCLC and contributes to malignant cell growth by cyclin D1 and ERK modulation, which makes Rsf-1 a candidate therapeutic target in lung cancer.

  18. Black holes in general relativity

    E-Print Network [OSTI]

    Visser, Matt

    2009-01-01

    What is going on (as of August 2008) at the interface between theoretical general relativity, string-inspired models, and observational astrophysics? Quite a lot. In this mini-survey I will make a personal choice and focus on four specific questions: Do black holes "exist"? (For selected values of the word "exist".) Is black hole formation and evaporation unitary? Can one mimic a black hole to arbitrary accuracy? Can one detect the presence of a horizon using local physics?

  19. www.yalecancercenter.org The Biology of Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org The Biology of Lung Cancer Guest Expert: Katerina Politi, PhD www lung cancers and cutaneous lymphomas. If you would like to join the conversation, you can contact

  20. NF-?B Fans the Flames of Lung Carcinogenesis

    E-Print Network [OSTI]

    Jacks, Tyler E.

    This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-?B and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating ...

  1. Differentiation of normal and cancerous lung tissues by multiphoton imaging

    E-Print Network [OSTI]

    Wang, Chun-Chin

    We utilize multiphoton microscopy for the label-free diagnosis of noncancerous, lung adenocarcinoma (LAC), and lung squamous cell carcinoma (SCC) tissues from humans. Our results show that the combination of second-harmonic ...

  2. CENTER FOR ENVIRONMENTAL MEDICINE, ASTHMA AND LUNG BIOLOGY PUBLICATIONS (2008)

    E-Print Network [OSTI]

    Crews, Stephen

    2008-01-01

    CENTER FOR ENVIRONMENTAL MEDICINE, ASTHMA AND LUNG BIOLOGY PUBLICATIONS (2008) Alexis NE, Muhlebach MS, Peden DB, Noah TL. Attenuation of host defense function of lung phagocytes in early cystic

  3. ORIGINAL RESEARCH Chung-Horng Lung Joseph E. Urban

    E-Print Network [OSTI]

    Lung, Chung-Horng

    ORIGINAL RESEARCH Chung-Horng Lung Æ Joseph E. Urban Gerald T. Mackulak Analogy-based domain problem that shares significant aspects with the past problem and C.-H. Lung (&) Department of Systems

  4. Quantum Mechanics and Black Holes

    E-Print Network [OSTI]

    Jose N. Pecina-Cruz

    2005-11-27

    This paper discusses the existence of black holes from the foundations of quantum mechanics. It is found that quantum mechanics rule out a possible gravitational collapse.

  5. Polarized Helium to Image the Lung

    E-Print Network [OSTI]

    Leduc, M; Leduc, Mich\\`{e}le; Nacher, Pierre-Jean

    2006-01-01

    The main findings of the european PHIL project (Polarised Helium to Image the Lung) are reported. State of the art optical pumping techniques for polarising ^3He gas are described. MRI methodological improvements allow dynamical ventilation images with a good resolution, ultimately limited by gas diffusion. Diffusion imaging appears as a robust method of lung diagnosis. A discussion of the potential advantage of low field MRI is presented. Selected PHIL results for emphysema are given, with the perspectives that this joint work opens up for the future of respiratory medicine.

  6. BUILD Program bridge to university for individuals with learning disabilities

    E-Print Network [OSTI]

    BUILD Program bridge to university for individuals with learning disabilities Now, you can get by participating in our new BUILD (Bridge to University for Individuals with Learning Disabilities) Program. Sign the school year knowing the critical information you need to be successful in university. The Bridge

  7. BUILD Program Bridge to University for Individuals with Learning Disabilities

    E-Print Network [OSTI]

    BUILD Program Bridge to University for Individuals with Learning Disabilities Now, you can get by participating in our new BUILD (Bridge to University for Individuals with Learning Disabilities) Program. Sign the school year knowing the critical information you need to be successful in university. The Bridge

  8. www.yalecancercenter.org Robotic Surgery for Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Robotic Surgery for Lung Cancer Guest Expert: Anthony Kim, MD Assistant and an expert in the use of radiation to treat lung cancers and cutaneous lymphomas. If you would like to join for a conversation about robotic surgery for lung cancer. Here is Francine Foss. Foss Let's start off by talking

  9. www.yalecancercenter.org Non-Small Cell Lung Cancer

    E-Print Network [OSTI]

    O'Hern, Corey S.

    www.yalecancercenter.org Non-Small Cell Lung Cancer Therapies Guest Expert: Roy Decker, MD, Ph Scott, let's start off by discussing why lung cancer is still such a significant public health problem it has decreased in the last 10- 15 years. The incidence of lung cancer might be decreasing a little

  10. A Bronchial Puncture Mechanism for Transoral Access to the Lung

    E-Print Network [OSTI]

    A Bronchial Puncture Mechanism for Transoral Access to the Lung Parenchyma Erik P. Lamers, Andria A University 1 Background More people die from lung cancer each year than any other form of cancer. Over 150 tool. The most common lung biopsy approaches are percutaneous and transoral. Percutaneous biopsy

  11. Nanostructure Changes in Lung Surfactant Monolayers Induced by Interactions between

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Nanostructure Changes in Lung Surfactant Monolayers Induced by Interactions between: October 4, 2002 Developing synthetic lung surfactants to replace animal extracts requires a fundamental understanding of the roles of the various lipids and proteins in native lung surfactant. We used Brewster angle

  12. Cardiopulmonary Function in RatsWith Lung Hemorrhage

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Cardiopulmonary Function in RatsWith Lung Hemorrhage Induced by Pulsed Ultrasound Exposure Jeffery using superthreshold exposure conditions known to produce sig- nificant lung hemorrhage. Methods. In 1 in the left lung of each rat. In a second group of 6 rats, 5 foci of ultrasound-induced hemorrhage were

  13. The Comprehensive Imaging-Based Analysis of the Lung

    E-Print Network [OSTI]

    Wang, Ge

    The Comprehensive Imaging-Based Analysis of the Lung: A Forum for Team Science1 Eric A. Hoffman, Ph description and understanding of the human lung and its response to disease, injury, and treatment, which for the need to volumetrically im- age the lung and to provide objective, quantitative measures characterizing

  14. Dynamic Lung Morphology of Methacholine-Induced Heterogeneous Bronchoconstriction

    E-Print Network [OSTI]

    Dynamic Lung Morphology of Methacholine-Induced Heterogeneous Bronchoconstriction Ben T. Chen and G). The method provides direct visualization of the venti- lated regions within the lung. Heterogeneous bronchoconstric- tion following the i.v. MCh injection was evident using this technique. These 3 He dynamic lung

  15. Tomographic Digital Subtraction Angiography for Lung Perfusion Estimation in Rodents

    E-Print Network [OSTI]

    Tomographic Digital Subtraction Angiography for Lung Perfusion Estimation in Rodents Cristian T. The capabilities of TDSA are established in studies on lung perfusion in rats. Using an imaging system developed in to therapeutics. Keywords X-ray; digital subtraction angiography; tomosynthesis; small animal; lung; perfusion

  16. Computerised lung sound analysis to improve the specificity of paediatric

    E-Print Network [OSTI]

    Elhilali, Mounya

    Computerised lung sound analysis to improve the specificity of paediatric pneumonia diagnosis that pulmonary pathology can be differentiated from normal using computerised lung sound analysis (CLSA). The authors will record lung sounds from 600 children aged #5 years, 100 each with consolidative pneumonia

  17. Predicting Panel Ratings for Semantic Characteristics of Lung Nodules

    E-Print Network [OSTI]

    Schaefer, Marcus

    Predicting Panel Ratings for Semantic Characteristics of Lung Nodules Dmitriy Zinovev De@cdm.depaul.edu ABSTRACT In reading CT scans with potentially malignant lung nodules, radiologists make use of high level a second opinion - predicting these semantic characteristics for lung nodules. In our previous work, we

  18. RESEARCH ARTICLE Open Access Occupational exposure to asbestos and lung

    E-Print Network [OSTI]

    Boyer, Edmond

    RESEARCH ARTICLE Open Access Occupational exposure to asbestos and lung cancer in men: evidence consistently demonstrated that workplace exposure to it increases the risk of developing lung cancer. Few of lung cancer, and 2,053 controls recruited from 8 Canadian provinces between 1994 and 1997. Self

  19. INVESTIGATION The Lsktm1 Locus Modulates Lung and Skin

    E-Print Network [OSTI]

    Broman, Karl W.

    INVESTIGATION The Lsktm1 Locus Modulates Lung and Skin Tumorigenesis in the Mouse Antonella Galvan to both skin and lung tumorigenesis over the susceptibility of the SWR/J strain. In an effort to map tumor.93) and lung (LOD score = 8.74) tumorigenesis. Two genes, Igfbp5 and Igfbp2, residing in this locus

  20. Measurement of Regional Lung Function in Rats Using Hyperpolarized 3

    E-Print Network [OSTI]

    Measurement of Regional Lung Function in Rats Using Hyperpolarized 3 Helium Dynamic MRI Ben T. Chen,* Anja C.S. Brau, and G. Allan Johnson Dynamic regional lung function was investigated in rats using by a constant flow ventila- tor. Based on regional differences in the behavior of inspired air, the lung

  1. Early Recognition of Lung's Air Sacs Wall Collapsing

    E-Print Network [OSTI]

    Boyer, Edmond

    Early Recognition of Lung's Air Sacs Wall Collapsing M. EMAM, J-F RENAUD de la Faverie, N. GHARBI discusses the possibility of applying a non- liner analysis approach on air density distribution within lung airways tree at any level of branching1. Computed Tomography (CT) 2 source images of the lung

  2. Cell Stem Cell Generation of Multipotent Lung and Airway

    E-Print Network [OSTI]

    Mootha, Vamsi K.

    Cell Stem Cell Article Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs.01.018 SUMMARY Deriving lung progenitors from patient-specific pluripotent cells is a key step in producing differenti- ated lung epithelium for disease modeling and trans- plantation. By mimicking the signaling

  3. NHLBI Workshop Future Directions in Early Cystic Fibrosis Lung

    E-Print Network [OSTI]

    Engelhardt, John F.

    NHLBI Workshop Future Directions in Early Cystic Fibrosis Lung Disease Research An NHLBI Workshop of Washington School of Medicine, Seattle, Washington; 3 National Heart, Lung, and Blood Institute, National substantial progress toward under- standing the molecular basis for CF lung disease, leading to the discovery

  4. Original article Lentivirus-induced interstitial lung disease

    E-Print Network [OSTI]

    Boyer, Edmond

    Original article Lentivirus-induced interstitial lung disease: pulmonary pathology in sheep a chronic disease in sheep affecting, among other organs, the lungs. Interstitial pneumonitis is similar the pathological features of lungs of sheep naturally infected with visna-maedi virus with the results obtained

  5. Visualization of Density Variation in Lung Aristofanes C. Silva

    E-Print Network [OSTI]

    Endler, Markus

    Visualization of Density Variation in Lung Nodules Arist´ofanes C. Silva e-mail: ari-Rio Inf.MCC09/02 June, 2002 Abstract We propose a method for visualize lung nodule, in order to emphasize, limiar. #12;1 Introduction Lung cancer is known to be the form of cancer with the smallest survival rate

  6. Lung Disease in Pediatrics: is it all in the Genes?

    E-Print Network [OSTI]

    Lung Disease in Pediatrics: is it all in the Genes? Jay K. Kolls, M.D.Jay K. Kolls, M.D. Chair with CF do worse than other? #12;· Outcomes are better at CF centers · There is huge variation in lung with the same mutation do worse than others? · Modifier genes ­ lung disease ­ Tgfb1 ­ Irfd1 ­ neutrophil

  7. Changes in Model Lung Surfactant Monolayers Induced by Palmitic Acid

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Changes in Model Lung Surfactant Monolayers Induced by Palmitic Acid Frank Bringezu, Junqi Ding of model lung surfactant lipid monolayers. Adding increasing fractions of palmitic acid (PA) to a 77/23 (wt to the rational design of replacement lung surfactants for the treatment of respiratory distress syndrome

  8. Biomaterials 28 (2007) 31313139 Towards improved artificial lungs through biocatalysis

    E-Print Network [OSTI]

    Federspiel, William J.

    2007-01-01

    Biomaterials 28 (2007) 3131­3139 Towards improved artificial lungs through biocatalysis Joel L in the development of artificial lungs and respiratory assist devices, which use hollow fiber membranes (HFMs intervention involves the use of mechan- ical ventilators to provide breathing support while the lungs recover

  9. ORIGINAL ARTICLE Effect of Different Sitting Postures on Lung Capacity,

    E-Print Network [OSTI]

    Makhsous, Mohsen

    ORIGINAL ARTICLE Effect of Different Sitting Postures on Lung Capacity, Expiratory Flow, and Lumbar, Makhsous M. Effect of different sitting postures on lung capacity, expiratory flow, and lumbar lordosis. Arch Phys Med Rehabil 2006;87:504-9. Objective: To investigate the effect of sitting posture on lung

  10. Lung, Artificial: Current Research and Future Directions William J. Federspiel

    E-Print Network [OSTI]

    Federspiel, William J.

    Lung, Artificial: Current Research and Future Directions William J. Federspiel Robert G. Svitek University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A. INTRODUCTION Artificial lungs are medical devices designed to take over or supplement the respiratory function of the lung: oxygenating the blood

  11. Evaluation of Plasma Resistant Hollow Fiber Membranes For Artificial Lungs

    E-Print Network [OSTI]

    Federspiel, William J.

    Evaluation of Plasma Resistant Hollow Fiber Membranes For Artificial Lungs HEIDE J. EASH,* HEATHER in artificial lungs (ox- ygenators) undergo plasma leakage (or wetting) in which blood plasma slowly fills2 gas permeance of a plasma resistant fiber imposes the greatest constraint upon artificial lung

  12. Lung Segmentation from CT with Severe Pathologies Using Anatomical Constraints

    E-Print Network [OSTI]

    Lung Segmentation from CT with Severe Pathologies Using Anatomical Constraints Neil Birkbeck Healthcare, Oxford, UK Abstract. The diversity in appearance of diseased lung tissue makes automatic segmentation of lungs from CT with severe pathologies chal- lenging. To overcome this challenge, we rely

  13. Computational Model for Forced Expiration from Asymmetric Normal Lungs

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Computational Model for Forced Expiration from Asymmetric Normal Lungs ADAM G. POLAK 1 losses along the airway branches. Calculations done for succeeding lung volumes result in the semidynamic to the choke points, characteristic differences of lung regional pressures and volumes, and a shape

  14. ORIGINAL RESEARCH Attenuation of Lipopolysaccharide-Induced Lung Vascular

    E-Print Network [OSTI]

    Gardel, Margaret

    ORIGINAL RESEARCH Attenuation of Lipopolysaccharide-Induced Lung Vascular Stiffening by Lipoxin Reduces Lung Inflammation Fanyong Meng1 , Isa Mambetsariev1 , Yufeng Tian1 , Yvonne Beckham2 , Angelo. Birukova1 1 Lung Injury Center, Section of Pulmonary and Critical Care Medicine, Department of Medicine

  15. Lung Cancer and Arsenic Concentrations in Drinking Water in Chile

    E-Print Network [OSTI]

    California at Berkeley, University of

    Lung Cancer and Arsenic Concentrations in Drinking Water in Chile Catterina Ferreccio,1,2 Claudia- trations have since been reduced to 40 g/liter. We investi- gated the relation between lung cancer and arsenic in drinking water in northern Chile in a case-control study involving patients diagnosed with lung

  16. Diversity of gene expression in adenocarcinoma of the lung

    E-Print Network [OSTI]

    Botstein, David

    Diversity of gene expression in adenocarcinoma of the lung Mitchell E. Garber*, Olga G. Troyanskaya Contributed by David Botstein, September 21, 2001 The global gene expression profiles for 67 human lung tumors pathologic analysis. Four main histologic subtypes of lung cancer are regularly distinguished by tumor

  17. Identification of Early Interstitial Lung Disease in Smokers from the

    E-Print Network [OSTI]

    Identification of Early Interstitial Lung Disease in Smokers from the COPDGene Study George R interstitial lung disease (ILD) on chest computed tomographic (CT) scans. Materials and Methods: The CT scans: Early interstitial lung disease; CT scan; smoker. ªAUR, 2010 I diopathic pulmonary fibrosis (IPF

  18. Asymmetries in Electrical Impedance Tomography Lung Images Bartlomiej Grychtol1

    E-Print Network [OSTI]

    Adler, Andy

    Asymmetries in Electrical Impedance Tomography Lung Images Bartlomiej Grychtol1 and Andy Adler2 1, it has been used to image the thorax, to monitor the movement of blood and gas in the heart and lungs. One key application of EIT is to determine the distribution of ventilation within the lungs

  19. Targeted CT Screening for Lung Cancer using Absolute Risk Prediction

    E-Print Network [OSTI]

    Brent, Roger

    Targeted CT Screening for Lung Cancer using Absolute Risk Prediction Stephanie A. Kovalchik skovalch@rand.org FHCRC 2014 Risk Prediction Symposium June 11, 2014 1 #12;Outline · Lung Cancer Epidemiology and Screening · Screening Benefit and Absolute Risk · Absolute Risk Model for Lung Cancer

  20. VARIATIONAL APPROACH FOR SEGMENTATION OF LUNG NODULES Amal A. Faraga

    E-Print Network [OSTI]

    Louisville, University of

    VARIATIONAL APPROACH FOR SEGMENTATION OF LUNG NODULES Amal A. Faraga , Hossam Abdelmunimab , James, Louisville, Kentucky g University of Louisville, Department of Radiology ABSTRACT Lung nodules from low dose CT (LDCT) scans may be used for early detection of lung cancer. However, these nodules vary in size

  1. -Glutamyl transferase deficiency results in lung oxidant stress in normoxia

    E-Print Network [OSTI]

    Marc, Robert E.

    -Glutamyl transferase deficiency results in lung oxidant stress in normoxia JYH CHANG JEAN,1 YUE E. Marc, Elizabeth Klings, and Martin Joyce-Brady. -Glutamyl transferase deficiency results in lung oxidant stress in normoxia. Am J Physiol Lung Cell Mol Physiol 283: L766­L776, 2002. First published May 3

  2. Buccal Spectral Markers for Lung Cancer Risk Stratification

    E-Print Network [OSTI]

    Hartline, Jason D.

    Buccal Spectral Markers for Lung Cancer Risk Stratification Andrew J. Radosevich1 *, Nikhil N, United States of America Abstract Lung cancer remains the leading cause of cancer deaths in the US with .150,000 deaths per year. In order to more effectively reduce lung cancer mortality, more sophisticated

  3. a bStomach Lung cell zone Clara cell

    E-Print Network [OSTI]

    Krasnow, Mark A.

    a bStomach Lung Chief-cell zone Stem-cell zone Mucus- cell zone Clara cell Tracheal airway Basal independent studies show that, if push comes to shove, differentiated cells of the stomach and lung can act and the other by Stange et al.2 published in Cell, find that followingdepletionofstemcellsinthestomach or lung

  4. EIT measurement of heart and lung perfusion Helga Ross1

    E-Print Network [OSTI]

    Adler, Andy

    EIT measurement of heart and lung perfusion Helga Ross1 , Benjamin J.W. Chow2 , and Andy Adler1 1. Introduction Electrical Impedance Tomography (EIT) shows promise for monitoring a patient's heart and lungs matching in the lungs. The goal of this research is to determine the accuracy of EIT measurements of blood

  5. Special Article Elucidating Nature's Solutions to Heart, Lung, and Blood

    E-Print Network [OSTI]

    Storz, Jay F.

    Special Article Elucidating Nature's Solutions to Heart, Lung, and Blood Diseases and Sleep defenses, and oxygen transport. In 2006, the National Heart, Lung, and Blood Institute released a funding understanding of nature's solutions to heart, lung, blood, and sleep disorders through future research

  6. Why Blue-Collar Blacks Help Less

    E-Print Network [OSTI]

    Smith, Sandra Susan; Young, Kara Alexis

    2013-01-01

    Exclude Black Men from Blue-Collar Jobs. Berkeley, CA:How Black and Latino Blue Collar Workers Make Decisionsof Sample Respondents Blue-Collar Latinos Blue-Collar Black

  7. Dermoscopy of black-spot poison ivy

    E-Print Network [OSTI]

    Rader, Ryan K; Mu, Ruipu; Shi, Honglan; Stoecker, William V; Hinton, Kristen A

    2012-01-01

    CT, Bean AS. Black-spot poison ivy: A rare phenomenon. J AmJG, Lucky AW. Black spot poison ivy: A report of 5 cases andis unique for black-spot poison ivy. The UFLC-MS/MS urushiol

  8. Green, Black, Lean Six Sigma and Master Black Belt Certifications

    E-Print Network [OSTI]

    Grissino-Mayer, Henri D.

    Green, Black, Lean Six Sigma and Master Black Belt Certifications Green BeLt CertifiCation Candidates may choose from three Green Belts offered: 1) Lean (one week of coursework) 2) Lean Six Sigma (two weeks of coursework) 3) Six Sigma (two weeks of coursework) Green Belt certification is a two

  9. Thermal BEC black holes

    E-Print Network [OSTI]

    Roberto Casadio; Andrea Giugno; Octavian Micu; Alessio Orlandi

    2015-11-04

    We review some features of BEC models of black holes obtained by means of the HWF formalism. We consider the KG equation for a toy graviton field coupled to a static matter current in spherical symmetry. The classical field reproduces the Newtonian potential generated by the matter source, while the corresponding quantum state is given by a coherent superposition of scalar modes with continuous occupation number. An attractive self-interaction is needed for bound states to form, so that (approximately) one mode is allowed, and the system of N bosons can be self-confined in a volume of the size of the Schwarzschild radius. The HWF is then used to show that the radius of such a system corresponds to a proper horizon. The uncertainty in the size of the horizon is related to the typical energy of Hawking modes: it decreases with the increasing of the black hole mass (larger number of gravitons), in agreement with semiclassical calculations and different from a single very massive particle. The spectrum contains a discrete ground state of energy $m$ (the bosons forming the black hole), and a continuous spectrum with energy $\\omega > m$ (representing the Hawking radiation and modelled with a Planckian distribution at the expected Hawking temperature). The $N$-particle state can be collectively described by a single-particle wave-function given by a superposition of a total ground state with energy $M = N m$ and a Planckian distribution for $E > M$ at the same Hawking temperature. The partition function is then found to yield the usual area law for the entropy, with a logarithmic correction related with the Hawking component. The backreaction of modes with $\\omega > m$ is also shown to reduce the Hawking flux and the evaporation properly stops for vanishing mass.

  10. Holographic Black Hole Chemistry

    E-Print Network [OSTI]

    Andreas Karch; Brandon Robinson

    2015-11-02

    Thermodynamic quantities associated with black holes in Anti-de Sitter space obey an interesting identity when the cosmological constant is included as one of the dynamical variables, the generalized Smarr relation. We show that this relation can easily be understood from the point of view of the dual holographic field theory. It amounts to the simple statement that the extensive thermodynamic quantities of a large $N$ gauge theory only depend on the number of colors, $N$, via an overall factor of $N^2$.

  11. A Case Report of 20 Lung Radiofrequency Ablation Sessions for 50 Lung Metastases from Parathyroid Carcinoma Causing Hyperparathyroidism

    SciTech Connect (OSTI)

    Tochio, Maki, E-mail: m-tochio@clin.medic.mie-u.ac.jp; Takaki, Haruyuki; Yamakado, Koichiro; Uraki, Junji; Kashima, Masataka; Nakatsuka, Atsuhiro [Mie University School of Medicine, Department of Radiology (Japan); Takao, Motoshi; Shimamoto, Akira; Tarukawa, Tomohito; Shimpo, Hideto [Mie University School of Medicine, Department of Thoracic and Cardiovascular Surgery (Japan); Takeda, Kan [Mie University School of Medicine, Department of Radiology (Japan)

    2010-06-15

    A 47-year-old man presented with multiple lung metastases from parathyroid carcinoma that caused hyperparathyroidism and refractory hypercalcemia. Lung radiofrequency (RF) ablation was repeated to decrease the serum calcium and parathyroid hormone levels and improve general fatigue. Pulmonary resection was combined for lung hilum metastases. The patient is still alive 4 years after the initial RF session. He has received 20 RF sessions for 50 lung metastases during this period.

  12. You Cannot Press Out the Black Hole

    E-Print Network [OSTI]

    Daisuke Ida; Takahiro Okamoto

    2012-01-03

    It is shown that a ball-shaped black hole region homeomorphic with D**n cannot be pressed out, along whichever axis penetrating the black hole region, into a black ring with a doughnut-shaped black hole region homeomorphic with S**1 x D**(n-1). A more general prohibition law for the change of the topology of black holes, including a version of no-bifurcation theorems for black holes, is given.

  13. Black Stars and Gamma Ray Bursts

    E-Print Network [OSTI]

    Tanmay Vachaspati

    2007-06-08

    Stars that are collapsing toward forming a black hole but are frozen near the Schwarzschild horizon are termed ``black stars''. Collisions of black stars, in contrast to black hole collisions, may be sources of gamma ray bursts, whose basic parameters are estimated quite simply and are found to be consistent with observed gamma ray bursts. Black star gamma ray bursts should be preceded by gravitational wave emission similar to that from the coalescence of black holes.

  14. Mouse models of lung cancer : understanding the molecular and cellular basis of lung tumorigenesis

    E-Print Network [OSTI]

    Jackson, Erica L. (Erica Lynn), 1973-

    2003-01-01

    Lung cancer is the leading cause of cancer deaths worldwide. Patients are typically diagnosed with advanced disease and have a high fatality:case ratio. Despite its prevalence, the identity of the cell of origin, precursor ...

  15. Small RNA combination therapy for lung cancer

    E-Print Network [OSTI]

    Tammela, Tuomas

    MicroRNAs (miRNAs) and siRNAs have enormous potential as cancer therapeutics, but their effective delivery to most solid tumors has been difficult. Here, we show that a new lung-targeting nanoparticle is capable of delivering ...

  16. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : What You Need To Know About High- tors for heart disease. In fact, the higher your blood cholesterol, the greater your risk of developing heart disease or having a heart attack. Heart disease is the #1 killer of men and women in the United

  17. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Physical Activity and Your Heart, is that even modest amounts of physi- cal activity are good for your health, especially your heart health activity is the type of physical activity that benefits your heart the most. This type of activity moves

  18. National Heart, Lung, and Blood Institute

    E-Print Network [OSTI]

    Shen, Jun

    National Heart, Lung, and Blood Institute A T - A - G L A N C E : Coronary Heart Disease C oronary heart disease (CHD), also called coronary artery disease, is the leading cause of death in the United. These arteries supply your heart muscle with oxygen-rich blood. Plaque is made up of fat, cholesterol, calcium

  19. Black Holes of Negative Mass

    E-Print Network [OSTI]

    R. B. Mann

    1997-05-06

    I demonstrate that, under certain circumstances, regions of negative energy density can undergo gravitational collapse into a black hole. The resultant exterior black hole spacetimes necessarily have negative mass and non-trivial topology. A full theory of quantum gravity, in which topology-changing processes take place, could give rise to such spacetimes.

  20. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University disabilities." www.chdd.washington.edu/outlook/Outlook_2012-Issue1.html 2012 Issue #1 LEND director Beth Ellen and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  1. Whole Slide Image Analysis Quantification using Aperio Digital Imaging in a Mouse Lung Metastasis Ronne L. Surface2

    E-Print Network [OSTI]

    Zhou, Yaoqi

    Whole Slide Image Analysis Quantification using Aperio Digital Imaging in a Mouse Lung Metastasis quantitate metastatic mouse lung tumors in a lung section using a H&E stain. Lung sections from a mouse lung of view from each slide representing a whole lung lobe with multiple lung metastases was selected

  2. Strings, higher curvature corrections, and black holes

    E-Print Network [OSTI]

    Thomas Mohaupt

    2005-12-05

    We review old and recent results on subleading contributions to black hole entropy in string theory.

  3. Physics: the big black box Mirror conjecture

    E-Print Network [OSTI]

    Cavalieri, Renzo

    Physics: the big black box Math Mirror conjecture A look into the mirror (I) an overview of Mirror Symmetry #12;Physics: the big black box Math Mirror conjecture Outline 1 Physics: the big black box 2 Math Symmetry #12;Physics: the big black box Math Mirror conjecture A slogan Mirror Symmetry is a correspondence

  4. Archival Report Autism with Intellectual Disability Related to

    E-Print Network [OSTI]

    McKeague, Ian

    Archival Report Autism with Intellectual Disability Related to Dynamics of Head Circumference dynamic features of head circumference growth are associated with autism. To address this issue, we; autism cases were identified from the Finnish Hospital and Outpatient Discharge Registry. METHODS

  5. Parents Raising Children with Disabilities: Predictors and Determinants of Wellbeing 

    E-Print Network [OSTI]

    Resch, James A.

    2012-10-19

    Background: The purpose of the present study was to identify and evaluate possible determinants of wellbeing and psychological adjustment in parents raising children with disabilities. Two studies drawing from the same sample of participants were...

  6. Disabilities and gender in the novels of Wilkie Collins 

    E-Print Network [OSTI]

    Agnew, Elizabeth L

    2013-02-22

    of their works reveals that the writers who tried to move beyond society's expectations were often inherently trapped within them. My thesis argues that Wilkie Collins's representations of characters with disabilities show that even though Collins intended...

  7. When Students Grieve: Teachers of Students With Intellectual Disabilities 

    E-Print Network [OSTI]

    McAdams-Ducy, Elizabeth

    2014-04-30

    The identification and provision of support for the emotional needs of children with intellectual disabilities is essential as these students are often “disenfranchised grievers”-- meaning their grief is not recognized by others. The purpose...

  8. Teaching Shape Recognition to Students with Significant Intellectual Disabilities

    E-Print Network [OSTI]

    Lyon, Kristin Joannou

    2014-05-31

    Little research on teaching mathematics to students with significant intellectual disabilities exists, and that which does exist is largely in the areas of number and money skills. All students, including students with ...

  9. Black hole horizons Eric Gourgoulhon

    E-Print Network [OSTI]

    Gourgoulhon, Eric

    on a black hole: up to 42% of the mass-energy mc2 of accreted matter ! NB: thermonuclear reactions release: a very deep gravitational potential well Release of potential gravitational energy by accretion

  10. Thermodynamics of regular black hole

    E-Print Network [OSTI]

    Yun Soo Myung; Yong-Wan Kim; Young-Jai Park

    2008-09-21

    We investigate thermodynamics for a magnetically charged regular black hole (MCRBH), which comes from the action of general relativity and nonlinear electromagnetics, comparing with the Reissner-Norstr\\"om (RN) black hole in both four and two dimensions after dimensional reduction. We find that there is no thermodynamic difference between the regular and RN black holes for a fixed charge $Q$ in both dimensions. This means that the condition for either singularity or regularity at the origin of coordinate does not affect the thermodynamics of black hole. Furthermore, we describe the near-horizon AdS$_2$ thermodynamics of the MCRBH with the connection of the Jackiw-Teitelboim theory. We also identify the near-horizon entropy as the statistical entropy by using the AdS$_2$/CFT$_1$ correspondence.

  11. Black Holes and Nuclear Dynamics

    E-Print Network [OSTI]

    David Merritt

    2006-02-17

    Supermassive black holes inhabit galactic nuclei, and their presence influences in crucial ways the evolution of the stellar distribution. The low-density cores observed in bright galaxies are probably a result of black hole infall, while steep density cusps like those at the Galactic center are a result of energy exchange between stars moving in the gravitational field of the single black hole. Loss-cone dynamics are substantially more complex in galactic nuclei than in collisionally-relaxed systems like globular clusters due to the wider variety of possible geometries and orbital populations. The rate of star-black hole interactions has begun to be constrained through observations of energetic events associated with stellar tidal disruptions.

  12. Characterization of Lung Tissues using Liquid-Crystal Tunable Filter and Hyperspectral Imaging System

    E-Print Network [OSTI]

    Won, Chang-Hee

    Characterization of Lung Tissues using Liquid-Crystal Tunable Filter and Hyperspectral Imaging to characterize lung tissue for detecting emphysematous tissues in lung volume reduction surgery. The system, the spectral signature of healthy lung tissue and simulated smokers lung tissue is obtained and compared

  13. Lung EIT: Should we reconstruct resistivity or conductivity? Bartlomiej Grychtol1

    E-Print Network [OSTI]

    Adler, Andy

    Lung EIT: Should we reconstruct resistivity or conductivity? Bartlomiej Grychtol1 , Andy Adler2 1.grychtol@dkfz.de MOTIVATION: In lung EIT, the quantity of interest is the change in regional air volume in the lungs. However. The model contains two non-conductive objects that represent the lungs. Assuming that lung resistivity

  14. Black Boundary Lines: Race, Class and Gender among Black Undergraduate Students

    E-Print Network [OSTI]

    Morales, Erica

    2012-01-01

    C. 1994. Behind the Mule: Race and Class in African AmericanHarlemworld: Doing Race and Class in Contemporary BlackBlue-Chip Black: Race, Class and Status in the New Black

  15. Method and apparatus for measuring lung density by Compton backscattering

    DOE Patents [OSTI]

    Loo, Billy W. (Oakland, CA); Goulding, Frederick S. (Lafayette, CA)

    1991-01-01

    The density of the lung of a patient suffering from pulmonary edema is monitored by irradiating the lung by a single collimated beam of monochromatic photons and measuring the energies of photons Compton backscattered from the lung by a single high-resolution, high-purity germanium detector. A compact system geometry and a unique data extraction scheme are utilized to monimize systematic errors due to the presence of the chestwall and multiple scattering.

  16. A System for Open-Access 3 He Human Lung

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    A System for Open-Access 3 He Human Lung Imaging at Very Low Field I.C. RUSET,1 L.L. TSAI,2,3 R describe a prototype system built to allow open-access very-low-field MRI of human lungs using laser images of human lungs. We include discussion on challenges unique to imaging at 50­200 kHz, including

  17. Method and apparatus for measuring lung density by Compton backscattering

    DOE Patents [OSTI]

    Loo, B.W.; Goulding, F.S.

    1988-03-11

    The density of the lung of a patient suffering from pulmonary edema is monitored by irradiating the lung by a single collimated beam of monochromatic photons and measuring the energies of photons compton back-scattered from the lung by a single high-resolution, high-purity germanium detector. A compact system geometry and a unique data extraction scheme are utilized to minimize systematic errors due to the presence of the chestwall and multiple scattering. 11 figs., 1 tab.

  18. Fishing in Black Holes

    E-Print Network [OSTI]

    A. Brotas

    2006-09-01

    The coordinate system $(\\bar{x},\\bar{t})$ defined by $r = 2m + K\\bar{x}- c K \\bar{t}$ and $t=\\bar{x}/cK - 1 /cK \\int_{r_a}^r (1- 2m/r + K^2)^{1/2} (1 - 2m/r)^{-1}dr$ allow us to write the Schwarzschild metric in the form: \\[ds^2=c^2 d\\bar{t}^2 + (W^2/K^2 - 2W/K) d\\bar{x}^2 + 2c (1 + W/K) d\\bar{x}d\\bar{t} - r^2 (d\\theta^2 + cos^2\\theta d\\phi^2)\\] with $W=(1 - 2m/r + K^2)^{1/2}$, in which the coefficients' pathologies are moved to $r_K = 2m/(1+K^2)$. This new coordinate system is used to study the entrance into a black hole of a rigid line (a line in which the shock waves propagate with velocity c).

  19. Cell Motility and Deformability in the Pathogenesis of Lung Cancer

    E-Print Network [OSTI]

    Pagano, Paul Carmelo

    2015-01-01

    and increased lung metastasis in NOD/SCID mice. Arch BiochemqPCR analysis Pathogen-free NOD-SCID gamma (NSG) mice were

  20. Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance

    E-Print Network [OSTI]

    Karsli-Uzunbas, Gizem

    Macroautophagy (autophagy hereafter) recycles intracellular components to sustain mitochondrial metabolism that promotes the growth, stress tolerance, and malignancy of lung cancers, suggesting that autophagy inhibition ...

  1. Toward A Quantitative Understanding of Gas Exchange in the Lung

    E-Print Network [OSTI]

    Chang, Yulin V

    2010-01-01

    In this work we present a mathematical framework that quantifies the gas-exchange processes in the lung. The theory is based on the solution of the one-dimensional diffusion equation on a simplified model of lung septum. Gases dissolved into different compartments of the lung are all treated separately with physiologically important parameters. The model can be applied in magnetic resonance of hyperpolarized xenon for quantification of lung parameters such as surface-to-volume ratio and the air-blood barrier thickness. In general this model provides a description of a broad range of biological exchange processes that are driven by diffusion.

  2. Sex-specific differences in hyperoxic lung injury in mice: Implications for acute and chronic lung disease in humans

    SciTech Connect (OSTI)

    Lingappan, Krithika, E-mail: lingappa@bcm.edu [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States); Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi I. [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States); Barrios, Roberto [Department of Pathology and Genomic Medicine, The Methodist Hospital Physician Organization, 6565 Fannin Street, Suite M227, Houston, TX 77030 (United States); Moorthy, Bhagavatula [Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, 1102 Bates Avenue, MC: FC530.01, Houston, TX 77030 (United States)

    2013-10-15

    Sex-specific differences in pulmonary morbidity in humans are well documented. Hyperoxia contributes to lung injury in experimental animals and humans. The mechanisms responsible for sex differences in the susceptibility towards hyperoxic lung injury remain largely unknown. In this investigation, we tested the hypothesis that mice will display sex-specific differences in hyperoxic lung injury. Eight week-old male and female mice (C57BL/6J) were exposed to 72 h of hyperoxia (FiO{sub 2} > 0.95). After exposure to hyperoxia, lung injury, levels of 8-iso-prostaglandin F{sub 2} alpha (8-iso-PGF 2?) (LC–MS/MS), apoptosis (TUNEL) and inflammatory markers (suspension bead array) were determined. Cytochrome P450 (CYP)1A expression in the lung was assessed using immunohistochemistry and western blotting. After exposure to hyperoxia, males showed greater lung injury, neutrophil infiltration and apoptosis, compared to air-breathing controls than females. Pulmonary 8-iso-PGF 2? levels were higher in males than females after hyperoxia exposure. Sexually dimorphic increases in levels of IL-6 (F > M) and VEGF (M > F) in the lungs were also observed. CYP1A1 expression in the lung was higher in female mice compared to males under hyperoxic conditions. Overall, our results support the hypothesis that male mice are more susceptible than females to hyperoxic lung injury and that differences in inflammatory and oxidative stress markers contribute to these sex-specific dimorphic effects. In conclusion, this paper describes the establishment of an animal model that shows sex differences in hyperoxic lung injury in a temporal manner and thus has important implications for lung diseases mediated by hyperoxia in humans. - Highlights: • Male mice were more susceptible to hyperoxic lung injury than females. • Sex differences in inflammatory markers were observed. • CYP1A expression was higher in females after hyperoxia exposure.

  3. Bruce Walcheck: Role of neutrophils in acute lung injury, bacterial lung infection, and sepsis (cell based assays and in vivo studies in mice).

    E-Print Network [OSTI]

    Blanchette, Robert A.

    Bruce Walcheck: Role of neutrophils in acute lung injury, bacterial lung infection, and sepsis, eosinophils, and macrophages in the ( ) oapplie lungs (cell based assays and in vivo studies in mice) Alice). Mike Murtaugh: Pathogenesis of lung inflammation during bacterial and viral pneumonia (cell based

  4. Lung Cancer: A Classic Example of Tumor Escape and Progression While Providing Opportunities for Immunological Intervention

    E-Print Network [OSTI]

    2012-01-01

    of lung cancer,” Clinical Cancer Research, vol. 4, no. 7,pathogenesis of lung cancer,” Annual Review of Physiology,immunoreac- tivity in lung cancer: yet another player in the

  5. Physiological and Computed Tomographic Predictors of Outcome from Lung Volume Reduction Surgery

    E-Print Network [OSTI]

    Physiological and Computed Tomographic Predictors of Outcome from Lung Volume Reduction Surgery: Previous investigations have identified several potential predictors of outcomes from lung volume reduction: To identify objective radiographic and physiological indices of lung disease that have prognostic value

  6. Lung Extraction, Lobe Segmentation and Hierarchical Region Assessment for Quantitative Analysis on High

    E-Print Network [OSTI]

    Lung Extraction, Lobe Segmentation and Hierarchical Region Assessment for Quantitative Analysis Care Division, Brigham and Women's Hospital, Boston, MA Abstract. Regional assessment of lung disease specific to different lung regions on high resolution computed tomography (HRCT) datasets. We present

  7. Dose impact in radiographic lung injury following lung SBRT: Statistical analysis and geometric interpretation

    SciTech Connect (OSTI)

    Yu, Victoria; Kishan, Amar U.; Cao, Minsong; Low, Daniel; Lee, Percy; Ruan, Dan

    2014-03-15

    Purpose: To demonstrate a new method of evaluating dose response of treatment-induced lung radiographic injury post-SBRT (stereotactic body radiotherapy) treatment and the discovery of bimodal dose behavior within clinically identified injury volumes. Methods: Follow-up CT scans at 3, 6, and 12 months were acquired from 24 patients treated with SBRT for stage-1 primary lung cancers or oligometastic lesions. Injury regions in these scans were propagated to the planning CT coordinates by performing deformable registration of the follow-ups to the planning CTs. A bimodal behavior was repeatedly observed from the probability distribution for dose values within the deformed injury regions. Based on a mixture-Gaussian assumption, an Expectation-Maximization (EM) algorithm was used to obtain characteristic parameters for such distribution. Geometric analysis was performed to interpret such parameters and infer the critical dose level that is potentially inductive of post-SBRT lung injury. Results: The Gaussian mixture obtained from the EM algorithm closely approximates the empirical dose histogram within the injury volume with good consistency. The average Kullback-Leibler divergence values between the empirical differential dose volume histogram and the EM-obtained Gaussian mixture distribution were calculated to be 0.069, 0.063, and 0.092 for the 3, 6, and 12 month follow-up groups, respectively. The lower Gaussian component was located at approximately 70% prescription dose (35 Gy) for all three follow-up time points. The higher Gaussian component, contributed by the dose received by planning target volume, was located at around 107% of the prescription dose. Geometrical analysis suggests the mean of the lower Gaussian component, located at 35 Gy, as a possible indicator for a critical dose that induces lung injury after SBRT. Conclusions: An innovative and improved method for analyzing the correspondence between lung radiographic injury and SBRT treatment dose has been demonstrated. Bimodal behavior was observed in the dose distribution of lung injury after SBRT. Novel statistical and geometrical analysis has shown that the systematically quantified low-dose peak at approximately 35 Gy, or 70% prescription dose, is a good indication of a critical dose for injury. The determined critical dose of 35 Gy resembles the critical dose volume limit of 30 Gy for ipsilateral bronchus in RTOG 0618 and results from previous studies. The authors seek to further extend this improved analysis method to a larger cohort to better understand the interpatient variation in radiographic lung injury dose response post-SBRT.

  8. Preparation of Pulmonary SMC Pulmonary smooth muscle cells are isolated from ten 6-day neonatal rat lungs.

    E-Print Network [OSTI]

    Mecham, Robert

    lungs. The lungs are dissected with the trachea still attached and placed in Puck's saline A solution

  9. Black hole mimickers: Regular versus singular behavior

    SciTech Connect (OSTI)

    Lemos, Jose P. S.; Zaslavskii, Oleg B.

    2008-07-15

    Black hole mimickers are possible alternatives to black holes; they would look observationally almost like black holes but would have no horizon. The properties in the near-horizon region where gravity is strong can be quite different for both types of objects, but at infinity it could be difficult to discern black holes from their mimickers. To disentangle this possible confusion, we examine the near-horizon properties, and their connection with far away asymptotic properties, of some candidates to black mimickers. We study spherically symmetric uncharged or charged but nonextremal objects, as well as spherically symmetric charged extremal objects. Within the uncharged or charged but nonextremal black hole mimickers, we study nonextremal {epsilon}-wormholes on the threshold of the formation of an event horizon, of which a subclass are called black foils, and gravastars. Within the charged extremal black hole mimickers we study extremal {epsilon}-wormholes on the threshold of the formation of an event horizon, quasi-black holes, and wormholes on the basis of quasi-black holes from Bonnor stars. We elucidate whether or not the objects belonging to these two classes remain regular in the near-horizon limit. The requirement of full regularity, i.e., finite curvature and absence of naked behavior, up to an arbitrary neighborhood of the gravitational radius of the object enables one to rule out potential mimickers in most of the cases. A list ranking the best black hole mimickers up to the worst, both nonextremal and extremal, is as follows: wormholes on the basis of extremal black holes or on the basis of quasi-black holes, quasi-black holes, wormholes on the basis of nonextremal black holes (black foils), and gravastars. Since in observational astrophysics it is difficult to find extremal configurations (the best mimickers in the ranking), whereas nonextremal configurations are really bad mimickers, the task of distinguishing black holes from their mimickers seems to be less difficult than one could think of it.

  10. Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed Natural Gas (CNG)-Powered Vehicles Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed...

  11. A Systematic Analysis of Epigenetic Genes across Different Stages of Lung Adenocarcinoma Akshay Desai1

    E-Print Network [OSTI]

    Zhou, Yaoqi

    A Systematic Analysis of Epigenetic Genes across Different Stages of Lung Adenocarcinoma Akshay across different stages of lung adenocarcinoma (LUAD). Method: An integrative system biology approach

  12. Lung Cancer (2005) 47, 41--47 Improving the specificity of fluorescence

    E-Print Network [OSTI]

    Duin, Robert P.W.

    2005-01-01

    Lung Cancer (2005) 47, 41--47 Improving the specificity of fluorescence bronchoscopy spectroscopy; Lung cancer; Bronchoscopy Summary Detection of malignancies of the bronchial tree in an early

  13. International black tea market integration and price discovery 

    E-Print Network [OSTI]

    Dharmasena, Kalu Arachchillage Senarath Dhananjaya Bandara

    2004-09-30

    In this thesis we study three basic issues related to international black tea markets: Are black tea markets integrated? Where is the price of black tea discovered? Are there leaders and followers in black tea markets? We ...

  14. Family Needs and Family Quality of Life for Taiwanese Families of Children with Intellectual Disability and Developmental Delay

    E-Print Network [OSTI]

    Chiu, Chun-Yu

    2013-05-31

    intellectual disability 95 28.5 Severe and profound intellectual disability 76 22.8 24 being, Physical/Material Well-being, and Disability-related Services. The Beach Center Scale has a satisfactory internal consistency (?=.88) and test... intellectual disability 95 28.5 Severe and profound intellectual disability 76 22.8 24 being, Physical/Material Well-being, and Disability-related Services. The Beach Center Scale has a satisfactory internal consistency (?=.88) and test...

  15. Energy on black hole spacetimes

    E-Print Network [OSTI]

    Alejandro Corichi

    2012-07-18

    We consider the issue of defining energy for test particles on a background black hole spacetime. We revisit the different notions of energy as defined by different observers. The existence of a time-like isometry allows for the notion of a total conserved energy to be well defined, and subsequently the notion of a gravitational potential energy is also meaningful. We then consider the situation in which the test particle is adsorbed by the black hole, and analyze the energetics in detail. In particular, we show that the notion of horizon energy es defined by the isolated horizons formalism provides a satisfactory notion of energy compatible with the particle's conserved energy. As another example, we comment a recent proposal to define energy of the black hole as seen by an observer at rest. This account is intended to be pedagogical and is aimed at the level of and as a complement to the standard textbooks on the subject.

  16. Heat Engine of black holes

    E-Print Network [OSTI]

    J. Sadeghi; Kh. Jafarzade

    2015-06-23

    As we know, the cosmological constant in different theories of gravity acts as a thermodynamics variable. The cosmological constant exists in different actions of gravity and also appears in the solution of such theories. These lead to use the black hole as a heat engines. Also, there are two values for the cosmological constant as positive and negative values. The case of negative cosmological constant supplies a natural realization of these engines in terms of the field theory description of the fluids to which they are holographically dual. In this paper, we are going to define heat engines for two different black holes as Dyonic BH and Kerr BH. And also, we calculate maximum efficiency for two black holes.

  17. Charged rotating dilaton black strings

    SciTech Connect (OSTI)

    Dehghani, M.H.; Farhangkhah, N.

    2005-02-15

    In this paper we, first, present a class of charged rotating solutions in four-dimensional Einstein-Maxwell-dilaton gravity with zero and Liouville-type potentials. We find that these solutions can present a black hole/string with two regular horizons, an extreme black hole or a naked singularity provided the parameters of the solutions are chosen suitable. We also compute the conserved and thermodynamic quantities, and show that they satisfy the first law of thermodynamics. Second, we obtain the (n+1)-dimensional rotating solutions in Einstein-dilaton gravity with Liouville-type potential. We find that these solutions can present black branes, naked singularities or spacetimes with cosmological horizon if one chooses the parameters of the solutions correctly. Again, we find that the thermodynamic quantities of these solutions satisfy the first law of thermodynamics.

  18. Quantum Criticality and Black Holes

    ScienceCinema (OSTI)

    Sachdev, Subir [Harvard University, Cambridge, Massachusetts, United States

    2009-09-01

    I will describe the behavior of a variety of condensed matter systems in the vicinity of zero temperature quantum phase transitions. There is a remarkable analogy between the hydrodynamics of such systems and the quantum theory of black holes. I will show how insights from this analogy have shed light on recent experiments on the cuprate high temperature superconductors. Studies of new materials and trapped ultracold atoms are yielding new quantum phases, with novel forms of quantum entanglement. Some materials are of technological importance: e.g. high temperature superconductors. Exact solutions via black hole mapping have yielded first exact results for transport coefficients in interacting many-body systems, and were valuable in determining general structure of hydrodynamics. Theory of VBS order and Nernst effect in cuprates. Tabletop 'laboratories for the entire universe': quantum mechanics of black holes, quark-gluon plasma, neutrons stars, and big-bang physics.

  19. Investigating the initiation and progression of small cell lung cancer

    E-Print Network [OSTI]

    Brauneis, Alison Dooley

    2011-01-01

    Small cell lung cancer (SCLC) comprises 18% of all lung cancer cases and is an aggressive disease with a five-year survival rate of less than 5%, mainly due to the advanced nature of the disease at the time of diagnosis. ...

  20. Black Holes and Galaxy Dynamics

    E-Print Network [OSTI]

    David Merritt

    1999-06-02

    The consequences of nuclear black holes for the structure and dynamics of stellar spheroids are reviewed. Slow growth of a black hole in a pre-existing core produces a steep power-law density profile similar to the cusps seen in faint elliptical galaxies. The weaker cusps in bright ellipticals may result from ejection of stars by a coalescing black-hole binary; there is marginal kinematical evidence for such a process having occurred in M87. Stellar orbits in a triaxial nucleus are mostly regular at radii where the gravitational force is dominated by the black hole; however the orbital shapes are not conducive to reinforcing the triaxial figure, hence nuclei are likely to be approximately axisymmetric. In triaxial potentials, a ``zone of chaos'' extends outward to a radius where the enclosed stellar mass is roughly 100 times the mass of the black hole; in this chaotic zone, no regular, box-like orbits exist. At larger radii, the phase space in triaxial potentials is complex, consisting of stochastic orbits as well as regular orbits associated with stable resonances. Figure rotation tends to increase the degree of stochasticity. Both test-particle integrations and N-body simulations suggest that a triaxial galaxy responds globally to the presence of a central mass concentration by evolving toward more axisymmetric shapes; the evolution occurs rapidly when the mass of the central object exceeds roughly 2% of the mass in stars. The lack of significant triaxiality in most early-type galaxies may be a consequence of orbital evolution induced by nuclear black holes.

  1. Radiation transport around Kerr black holes

    E-Print Network [OSTI]

    Schnittman, Jeremy David

    2005-01-01

    This Thesis describes the basic framework of a relativistic ray-tracing code for analyzing accretion processes around Kerr black holes. We begin in Chapter 1 with a brief historical summary of the major advances in black ...

  2. Does phantom energy produce black hole?

    E-Print Network [OSTI]

    F. Rahaman; A. Ghosh; M. Kalam

    2006-12-23

    We have found an exact solution of spherically symmetrical Einstein equations describing a black hole with a special type phantom energy source. It is surprising to note that our solution is analogous to Reissner-Nordstr\\"{o}m black hole.

  3. Introduction to Black Hole Evaporation

    E-Print Network [OSTI]

    Pierre-Henry Lambert

    2014-01-16

    These lecture notes are an elementary and pedagogical introduction to the black hole evaporation, based on a lecture given by the author at the Ninth Modave Summer School in Mathematical Physics and are intended for PhD students. First, quantum field theory in curved spacetime is studied and tools needed for the remaining of the course are introduced. Then, quantum field theory in Rindler spacetime in 1+1 dimensions and in the spacetime of a spherically collapsing star are considered, leading to Unruh and Hawking effects, respectively. Finally, some consequences such as thermodynamics of black holes and information loss paradox are discussed.

  4. 4d neutral dilatonic black holes and (4+p) dimensional nondilatonic black p-branes

    E-Print Network [OSTI]

    J. R. Morris

    2000-01-11

    It is shown that, in contrast to the case of extreme 4d dilatonic black holes, 4d neutral dilatonic black holes with horizon singularities can not be interpreted as nonsingular nondilatonic black p-branes in (4+p) dimensions, regardless of the number of extra dimensions p. That is, extra dimensions do not remove naked singularities of 4d neutral dilatonic black holes.

  5. Classical and thermodynamic stability of black holes

    E-Print Network [OSTI]

    Ricardo Monteiro

    2010-06-28

    We consider the stability of black holes within both classical general relativity and the semiclassical thermodynamic description. In particular, we study linearised perturbations and their contribution to the gravitational partition function, addressing technical issues for charged (Reissner-Nordstrom) and rotating (Kerr-AdS) black holes. Exploring the connection between classical and thermodynamic stability, we find classical instabilities of Myers-Perry black holes and bifurcations to new black hole families.

  6. Will black holes eventually engulf the universe?

    E-Print Network [OSTI]

    Prado Martin-Moruno; Jose A. Jimenez Madrid; Pedro F. Gonzalez-Diaz

    2006-03-28

    The Babichev-Dokuchaev-Eroshenko model for the accretion of dark energy onto black holes has been extended to deal with black holes with non-static metrics. The possibility that for an asymptotic observer a black hole with large mass will rapidly increase and eventually engulf the Universe at a finite time in the future has been studied by using reasonable values for astronomical parameters. It is concluded that such a phenomenon is forbidden for all black holes in quintessential cosmological models.

  7. Hawking Emission and Black Hole Thermodynamics

    E-Print Network [OSTI]

    Don N. Page

    2006-12-18

    A brief review of Hawking radiation and black hole thermodynamics is given, based largely upon hep-th/0409024.

  8. A survey of reading services provided to students with reading disabilities 

    E-Print Network [OSTI]

    Christen, Margaret Harding

    2009-05-15

    of special education services provided. Results showed that there was minimal provision of special education services for reading disabled students. When the results were analyzed by degree of disability the correlation was weak while the analysis...

  9. A Model of Accessibility Services Provision for Students with Disabilities in Higher Education

    E-Print Network [OSTI]

    Kouroupetroglou, Georgios

    23 A Model of Accessibility Services Provision for Students with Disabilities in Higher Education, Accessibility Service, Universal Learning Design, Tertiary Education, Assistive Technologies, Accessibility, Educational Facilities Abstract The number of universities offering services for students with disabilities

  10. Academic Handbook, Appeals, Accommodation for Students with Disabilities Handbook Page 1 Issued: 2008 08

    E-Print Network [OSTI]

    Lennard, William N.

    Academic Handbook, Appeals, Accommodation for Students with Disabilities Handbook Page 1 Issued: 2008 08 Faculty Handbook on the Implementation of the Policy on Academic Accommodation for Students individual will benefit others with and without disabilities. #12;Academic Handbook, Appeals, Accommodation

  11. Mann Hall at UVM -Home to CDCI Center on Disability and Community Inclusion

    E-Print Network [OSTI]

    Hayden, Nancy J.

    Vermont's University Center for Excellence in Developmental Disabilities Research, Education, and Service e University of Vermont www.uvm.edu/~cdci With Vermonters and our Vermont Sister Organizations: · VermontDD Council · DisabilityRights Vermont · VTLENDSTATEWIDE COLLABORATION #12;

  12. Stuck in a Loop: Individual and System Barriers for Job Seekers with Disabilities

    E-Print Network [OSTI]

    Hall, Jean P.; Parker, K.

    2010-03-01

    for job seekers with disabilities. This population frequently experiences employment barriers beyond those of able-bodied job seekers, including significantly lower self-esteem. Service providers need and want information about disability but do not know...

  13. Using Ecological Momentary Assessment to Monitor Community Participation of People with Mobility-Related Disabilities

    E-Print Network [OSTI]

    Gonda, Chiaki

    2011-06-27

    Increased community participation of people with disabilities is a goal of many community-based disability organizations. Researchers used an ecological momentary assessment (EMA) approach to investigate factors that might increase community...

  14. Lung tissue engineering : in vitro synthesis of lung tissue from neonatal and fetal rat lung cells cultured in a three-dimensional collagen matrix

    E-Print Network [OSTI]

    Chen, Patty P., 1981-

    2004-01-01

    The focus of this study was to investigate the histology of tissue formed when fetal (16-20 days gestation) and neonatal (2 days old) rat lung cells were grown in a collagen-glycosaminoglycan scaffold. This project employed ...

  15. Scattering by regular black holes: Planar massless scalar waves impinging upon a Bardeen black hole

    E-Print Network [OSTI]

    Macedo, Caio F B; Crispino, Luís C B

    2015-01-01

    Singularities are common features of general relativity black holes. However, within general relativity, one can construct black holes that present no singularities. These regular black hole solutions can be achieved by, for instance, relaxing one of the energy conditions on the stress energy tensor sourcing the black hole. Some regular black hole solutions were found in the context of non-linear electrodynamics, the Bardeen black hole being the first one proposed. In this paper, we consider a planar massless scalar wave scattered by a Bardeen black hole. We compare the scattering cross section computed using a partial-wave description with the classical geodesic scattering of a stream of null geodesics, as well as with the semi-classical glory approximation. We obtain that, for some values of the corresponding black hole charge, the scattering cross section of a Bardeen black hole has a similar interference pattern of a Reissner-Nordstr\\"om black hole.

  16. Scattering by regular black holes: Planar massless scalar waves impinging upon a Bardeen black hole

    E-Print Network [OSTI]

    Caio F. B. Macedo; Ednilton S. de Oliveira; Luís C. B. Crispino

    2015-06-26

    Singularities are common features of general relativity black holes. However, within general relativity, one can construct black holes that present no singularities. These regular black hole solutions can be achieved by, for instance, relaxing one of the energy conditions on the stress energy tensor sourcing the black hole. Some regular black hole solutions were found in the context of non-linear electrodynamics, the Bardeen black hole being the first one proposed. In this paper, we consider a planar massless scalar wave scattered by a Bardeen black hole. We compare the scattering cross section computed using a partial-wave description with the classical geodesic scattering of a stream of null geodesics, as well as with the semi-classical glory approximation. We obtain that, for some values of the corresponding black hole charge, the scattering cross section of a Bardeen black hole has a similar interference pattern of a Reissner-Nordstr\\"om black hole.

  17. New approaches to black holes Eric Gourgoulhon

    E-Print Network [OSTI]

    Gourgoulhon, Eric

    References Eric Gourgoulhon (LUTH) New approaches to black holes Okinawa Nat. Col. Tech., 17 Aug 2008 2 / 36 Gourgoulhon (LUTH) New approaches to black holes Okinawa Nat. Col. Tech., 17 Aug 2008 3 / 36 #12;Local (2006)] Eric Gourgoulhon (LUTH) New approaches to black holes Okinawa Nat. Col. Tech., 17 Aug 2008 4

  18. From Pinholes to Black Holes

    SciTech Connect (OSTI)

    Fenimore, Edward E.

    2014-10-06

    Pinhole photography has made major contributions to astrophysics through the use of “coded apertures”. Coded apertures were instrumental in locating gamma-ray bursts and proving that they originate in faraway galaxies, some from the birth of black holes from the first stars that formed just after the big bang.

  19. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University with FXS and ASD, which, in turn, can help families and practitioners who work with these children. www.chdd.washington.edu/outlook/CHDD_Outlook and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  20. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University finds its target, in this case the muscle www.chdd.washington.edu/outlook/CHDD_Outlook_2015_2.pdf 2015 and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  1. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University or duplications www.chdd.washington.edu/outlook/CHDD_Outlook_2012_3.pdf 2012 Issue #3 Fuki Hisama, the medical and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  2. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University opportunities into play. Some of the families will be taught using experimental teaching methods aimed www.chdd.washington.edu/outlook/CHDD_Outlook and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  3. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University for mutations in genes that might be linked to human disease. Then, by knocking things out in a neuron www.chdd.washington.edu/outlook/CHDD_Outlook and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  4. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University embryos, the fish developed larger heads and wide-set eyes. The www.chdd.washington.edu/outlook/CHDD_Outlook and Developmental Disabilities Research Center. CHDD Outlook Center on Human Development and Disability, University

  5. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    of Washington CHDD IDDRC UCEDD Understanding the Connection Between Intellectual Disability and Juvenile Justice), is collaborating with the Washington State Developmental Disabilities Council and Disability Rights Washington of Washington Trust Fund, a nonprofit organization that promotes the rights of people with IDD, Brown

  6. Extremal Higher Spin Black Holes

    E-Print Network [OSTI]

    Máximo Bañados; Alejandra Castro; Alberto Faraggi; Juan I. Jottar

    2015-11-30

    The gauge sector of three-dimensional higher spin gravities can be formulated as a Chern-Simons theory. In this context, a higher spin black hole corresponds to a flat connection with suitable holonomy (smoothness) conditions which are consistent with the properties of a generalized thermal ensemble. Building on these ideas, we discuss a definition of black hole extremality which is appropriate to the topological character of 3d higher spin theories. Our definition can be phrased in terms of the Jordan class of the holonomy around a non-contractible (angular) cycle, and we show that it is compatible with the zero-temperature limit of smooth black hole solutions. While this notion of extremality does not require nor implies the existence of supersymmetry, we exemplify its consequences in the context of sl(3|2) + sl(3|2) Chern-Simons theory. Remarkably, while as usual not all extremal solutions preserve supersymmetries, we find that the higher spin setup allows for non-extremal supersymmetric black hole solutions as well. Furthermore, we discuss our results from the perspective of the holographic duality between sl(3|2) + sl(3|2) Chern-Simons theory and two-dimensional CFTs with W_{(3|2)} symmetry, the simplest higher spin extension of the N=2 super-Virasoro algebra. In particular, we compute W_{(3|2)} BPS bounds at the full quantum level, and relate their semiclassical limit to extremal black hole or conical defect solutions in the 3d bulk. Along the way, we discuss the role of the spectral flow automorphism and provide a conjecture for the form of the semiclassical BPS bounds in general N=2 two-dimensional CFTs with extended symmetry algebras.

  7. Black hole microstates in AdS

    E-Print Network [OSTI]

    Shaghoulian, Edgar

    2015-01-01

    We extend a recently derived higher-dimensional Cardy formula to include angular momenta, which we use to obtain the Bekensten-Hawking entropy of AdS black branes, compactified rotating branes, and large Schwarzschild/Kerr black holes. This is the natural generalization of Strominger's microscopic derivation of the BTZ black hole entropy to higher dimensions. We propose an extension to include $U(1)$ charge, which agrees with the Bekenstein-Hawking entropy of large Reissner-Nordstrom/Kerr-Newman black holes at high temperature. We extend the results to arbitrary hyperscaling violation exponent (this captures the case of black D$p$-branes as a subclass) and reproduce logarithmic corrections.

  8. Single-Session Radiofrequency Ablation of Bilateral Lung Metastases

    SciTech Connect (OSTI)

    Palussiere, Jean, E-mail: palussiere@bergonie.org; Gomez, Fernando; Cannella, Matthieu; Ferron, Stephane; Descat, Edouard [Institut Bergonie, Department of Radiology, Regional Cancer Centre (France); Fonck, Marianne [Institut Bergonie, Department of Digestive Oncology (France); Brouste, Veronique [Institut Bergonie, Clinical and Epidemiological Research Unit (France); Avril, Antoine [Institut Bergonie, Department of Surgery (France)

    2012-08-15

    Purpose: This retrospective study examined the feasibility and efficacy of bilateral lung radiofrequency ablation (RFA) performed in a single session. Methods: From 2002-2009, patients with bilateral lung metastases were treated by RFA, where possible in a single session under general anesthesia with CT guidance. The second lung was punctured only if no complications occurred after treatment of the first lung. Five lung metastases maximum per patient were treated by RFA and prospectively followed. The primary endpoint was the evaluation of acute and delayed complications. Secondary endpoints were calculation of hospitalization duration, local efficacy, median survival, and median time to tumor progression. Local efficacy was evaluated on CT or positron emission tomography (PET) CT. Results: Sixty-seven patients were treated for bilateral lung metastases with RFA (mean age, 62 years). Single-session treatment was not possible in 40 due to severe pneumothoraces (n = 24), bilateral pleural contact (n = 14), and operational exclusions (n = 2). Twenty-seven (41%) received single-session RFA of lesions in both lungs for 66 metastases overall. Fourteen unilateral and four bilateral pneumothoraces occurred (18 overall, 66.7%). Unilateral (n = 13) and bilateral (n = 2) chest tube drainage was required. Median hospitalization was 3 (range, 2-8) days. Median survival was 26 months (95% confidence interval (CI), 19-33). Four recurrences on RFA sites were observed (4 patients). Median time to tumor progression was 9.5 months (95% CI, 4.2-23.5). Conclusions: Although performing single-session bilateral lung RFA is not always possible due to pneumothoraces after RFA of first lung, when it is performed, this technique is safe and effective.

  9. He Lung Imaging in an Open Access, Very-Low-Field Human Magnetic Resonance Imaging System

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    3 He Lung Imaging in an Open Access, Very-Low-Field Human Magnetic Resonance Imaging System R. W. Butler,6 F. W. Hersman,4 and R. L. Walsworth1 The human lung and its functions are extremely sensitive lung restrict sub- jects to lying horizontally. Imaging of human lungs using inhaled laser-polarized 3

  10. COMPUTERS AND BIOMEDICAL RESEARCH 17, 580-589 ( 1984) Multicompartment Model of Lung Dynamics*

    E-Print Network [OSTI]

    Longtin, André

    COMPUTERS AND BIOMEDICAL RESEARCH 17, 580-589 ( 1984) Multicompartment Model of Lung Dynamics* B of the lungs. The lungs are represented by 24 compartments each corresponding to a generation of the Weibel model A. In the model it is assumed that gases are transported in the lungs by convection and diffusion

  11. Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells

    E-Print Network [OSTI]

    Boyer, Edmond

    1 Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells Corinne expression in lung adenocarcinoma cells HALauthormanuscriptinserm-00143972,version1 HAL author manuscript Lung Cancer 56, 2 (2007) 167-74 #12;2 Summary In lung adenocarcinoma, expression of Regulated upon

  12. Automated Lung Nodule Segmentation Using Dynamic Programming and EM Based Classification

    E-Print Network [OSTI]

    Ahuja, Narendra

    Automated Lung Nodule Segmentation Using Dynamic Programming and EM Based Classification Ning Xua a robust and automated algorithm to segment lung nodules in three dimensional (3D) Computed Tomography (CT nodules but also the nodules attached to lung walls and vessels. Keywords: Lung nodule, Segmentation

  13. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

    E-Print Network [OSTI]

    Cai, Long

    Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer, Timothy Anderson6, Norman Gerry7, Joseph Keane4, Marc E Lenburg7 & Jerome S Brody1 Lung cancer smokers with suspicion of lung cancer could be used as a lung cancer biomarker. Using a training set (n

  14. Ultrasound-induced lung hemorrhage: Role of acoustic boundary conditions at the pleural surface

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Ultrasound-induced lung hemorrhage: Role of acoustic boundary conditions at the pleural surface intercostal tissue and lung was evaluated as a possible explanation for the enhanced lung damage the volume of air inspired and expired. The acoustic impedance difference between intercostal tissue and lung

  15. NEURAL PCA NETWORK FOR LUNG OUTLINE RECONSTRUCTION IN VQ SCAN IMAGES

    E-Print Network [OSTI]

    Serpen, Gursel

    NEURAL PCA NETWORK FOR LUNG OUTLINE RECONSTRUCTION IN VQ SCAN IMAGES G. Serpen1 , Ph. D., R. Iyer1 system takes the digitized ventilation-perfusion scan images of lungs as input, identify a template according to the size and shape of the lungs and thereby approximate and reconstruct the outline of the lung

  16. EFFECT OF VELOCITY CONTROL ON KINESTHETIC LUNG TUMOUR LOCALIZATION M. D. Naish1,2,3

    E-Print Network [OSTI]

    Naish, Michael D.

    EFFECT OF VELOCITY CONTROL ON KINESTHETIC LUNG TUMOUR LOCALIZATION M. D. Naish1,2,3 , G. L. Mc precludes manual palpation, making the localization of lung tumours chal- lenging. This paper investigates on stiffness variations of the lung parenchyma. Agar injected into ex vivo porcine lungs produced a model

  17. Automatic Lung Nodule Detection from Chest CT Data Using Geometrical Features: Initial Results

    E-Print Network [OSTI]

    Whelan, Paul F.

    Automatic Lung Nodule Detection from Chest CT Data Using Geometrical Features: Initial Results for automatic lung nodule detection from Chest CT data is proposed. The proposed system includes the methods of lung segmentation and nodule detection from CT data. The algorithm for lung segmentation consists

  18. Respiratory Physiology & Neurobiology 131 (2002) 233243 Relative motion of lung and chest wall promotes uniform

    E-Print Network [OSTI]

    Federspiel, William J.

    2002-01-01

    Respiratory Physiology & Neurobiology 131 (2002) 233­243 Relative motion of lung and chest wall, USA b Artificial Lung Program, Uni6ersity of Pittsburgh, Pittsburgh, PA 15260, USA c Department of lung par- enchyma and effective inspiratory action of the diaphragm, the lungs and chest wall must

  19. Impedance measurements of ex vivo rat lung at different volumes of inflation

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Impedance measurements of ex vivo rat lung at different volumes of inflation Michael L. Oelze that the occurrence of ultrasonically induced lung hemorrhage in rats was directly correlated to the level of lung inflation. In that study, it was hypothesized that the lung could be modeled as two components consisting

  20. Evaluation of a Pumping Assist Lung That Uses a Rotating Fiber Bundle

    E-Print Network [OSTI]

    Federspiel, William J.

    Evaluation of a Pumping Assist Lung That Uses a Rotating Fiber Bundle ROBERT G. SVITEK,* BRIAN J. FRANKOWSKI,* AND WILLIAM J. FEDERSPIEL,*§ A paracorporeal respiratory assist lung (PRAL) is being devel- oped for supplemental gas exchange to allow the native lungs of acute lung failure patients to heal. The device consists

  1. Mesenchymal Nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation

    E-Print Network [OSTI]

    Gronostajski, Richard M.

    lung maturation Yu-Chih Hsu a , Jason Osinski a , Christine E. Campbell a , E. David Litwack b , Dan 2011 Accepted 6 April 2011 Available online 13 April 2011 Keywords: NFI-B Lung development Mesenchymal is expressed in both lung mesenchyme and epithelium and mice lacking Nfib have severe lung maturation defects

  2. Lung Cancer (2004) 46, 333--340 High serum YKL-40 level in patients with small

    E-Print Network [OSTI]

    Price, Paul A.

    2004-01-01

    Lung Cancer (2004) 46, 333--340 High serum YKL-40 level in patients with small cell lung cancer May 2004; accepted 6 May 2004 KEYWORDS Small cell lung carcinoma; Tumor invasiveness; YKL-40; HC gp-39 evaluated serum YKL-40 in 131 patients with small cell lung cancer (SCLC). Twenty-two percent

  3. A Novel Laminin E8 Cell Adhesion Site Required for Lung Alveolar Formation In Vitro

    E-Print Network [OSTI]

    A Novel Laminin E8 Cell Adhesion Site Required for Lung Alveolar Formation In Vitro Michelle L,UniversityofVirginia,Charlottesville,Virginia22908 Abstract. Basement membrane-adherent type II alveo- lar cells isolated from lung assemble with a key role in lung alveolar morphogenesis. M ORPHOGENESISof lung alveoli, the functional unit ofbi

  4. Lung squamous cell carcinoma (SCC) is the second most frequent histologic subtype of

    E-Print Network [OSTI]

    Pajarola, Renato B.

    ·Topic Lung squamous cell carcinoma (SCC) is the second most frequent histologic subtype of lung cancer displaying a frequency of 25% among all lung cancers. This subtype is morphologically. The aim of this project is to help model the 3D architecture and shape of human lung squamous cell

  5. Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms1

    E-Print Network [OSTI]

    Bernal, Javier

    Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms1 Adele P. Peskin of synthetic lung tumor data in which synthetic tumors of known volume are embedded in clinical lung computerized tomographic (CT) data in different background settings in the lung. Because the change

  6. Lung Cancer 86 (2014) 7884 Contents lists available at ScienceDirect

    E-Print Network [OSTI]

    Hemminki, Akseli

    2014-01-01

    Lung Cancer 86 (2014) 78­84 Contents lists available at ScienceDirect Lung Cancer journal homepage: www.elsevier.com/locate/lungcan Metastatic sites and survival in lung cancer M. Riihimäkia,b, , A Lung metastasis Brain metastasis Liver metastasis a b s t r a c t Objectives: Population-based data

  7. Level Set based Reconstruction Algorithm for EIT Lung Images: First Clinical Results

    E-Print Network [OSTI]

    Adler, Andy

    Level Set based Reconstruction Algorithm for EIT Lung Images: First Clinical Results Peyman Rahmati of a slow flow inflation pressure-volume manoeuvre in lung healthy and adult lung injury patients. Images conductivity changes in the distribution of lung ventilation using the level set based reconstruction method. 1

  8. Elastin protein levels are a vital modifier affecting normal lung development and susceptibility to emphysema

    E-Print Network [OSTI]

    Mecham, Robert

    Elastin protein levels are a vital modifier affecting normal lung development and susceptibility modifier affecting normal lung development and susceptibility to emphysema. Am J Physiol Lung Cell Mol-induced emphysema is highly variable, and numerous genetic and environmental factors are thought to mitigate lung

  9. TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk factors

    E-Print Network [OSTI]

    TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk mutations are observed in about 40e70% of lung cancer tissues, and the hot spot codon mu- tations factors that influence TP53 gene mutation in lung cancer patients residing areas with high lung cancer

  10. The Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network

    E-Print Network [OSTI]

    Johnson, Aaron

    }@informatik.hu-berlin.de Abstract--Tor is a distributed onion-routing network used for achieving anonymity and resisting censorship and transferring roughly 3 GiB/s in aggregate [8]. Tor uses onion routing [25] to route clients' traffic throughThe Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network Rob Jansen Florian

  11. The Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network

    E-Print Network [OSTI]

    }@informatik.hu-berlin.de Abstract--Tor is a distributed onion-routing network used for achieving anonymity and resisting censorshipB/s in aggregate [4]. Tor uses onion routing [5] to route clients' traffic through a circuit of geo- graphicallyThe Sniper Attack: Anonymously Deanonymizing and Disabling the Tor Network Rob Jansen Florian

  12. Access to Assistance for Students with Disabilities / Health Condition

    E-Print Network [OSTI]

    Wapstra, Erik

    have the right to request access to your personal information held by the University in accordance. Disability Service Personal Information Statement Your personal information is being collected by the Student-related services and course adjustments. Failure to provide this information may result in you not receiving course

  13. Resource Guide to Programs and Services for Students with Disabilities

    E-Print Network [OSTI]

    Slatton, Clint

    , 2006 Welcome to the 6th Edition of the Resource Guide: The Resource Guide to Programs and ServicesResource Guide to Programs and Services for Students with Disabilities Attending State Funded Public Universities in Florida Sixth Edition, January 2, 2006© All portions of this book may

  14. The Enfreakment of Language: Disability, Eugenics, and Rhetoric 

    E-Print Network [OSTI]

    Wheeler, Stephanie K

    2014-03-31

    of representations of disability and eugenics in America to illustrate reproductions of the freak show and eugenicist practices within the production and consumption of the “abnormal” body. I first show how a system based on eugenicist logic operates by examining how...

  15. LOCOMOTION CONTROL CYCLES ADAPTED FOR DISABILITIES IN HEXAPOD ROBOTS

    E-Print Network [OSTI]

    Parker, Gary B.

    LOCOMOTION CONTROL CYCLES ADAPTED FOR DISABILITIES IN HEXAPOD ROBOTS GARY B. PARKER and INGO CYLIAX to repeat. This is no more apparent than in the locomotion of hexapod robots. The movement of the separate Algorithms which have successfully been used to generate gaits for actual hexapod robots. In this paper, we

  16. Exploring and exchanging (dis)ability and (dis)aster 

    E-Print Network [OSTI]

    Stough, Laura; Kelman, Ilan

    2015-01-01

    and deal with, leaving them less energy for dealing with less frequent hazards. Some chapters point out that disasters can also lead to disability, from Ferreira losing her leg in a nightclub fire to Mr. HP and Mrs. KB experiencing the Gujarat...

  17. Multi-scale analysis of lung computed tomography images

    E-Print Network [OSTI]

    Gori, I; Fantacci, M E; Martinez, A Preite; Retico, A; De Mitri, I; Donadio, S; Fulcheri, C; Gargano, G; Magro, R; Santoro, M; Stumbo, S; 10.1088/1748-0221/2/09/P09007

    2009-01-01

    A computer-aided detection (CAD) system for the identification of lung internal nodules in low-dose multi-detector helical Computed Tomography (CT) images was developed in the framework of the MAGIC-5 project. The three modules of our lung CAD system, a segmentation algorithm for lung internal region identification, a multi-scale dot-enhancement filter for nodule candidate selection and a multi-scale neural technique for false positive finding reduction, are described. The results obtained on a dataset of low-dose and thin-slice CT scans are shown in terms of free response receiver operating characteristic (FROC) curves and discussed.

  18. Tumour microenvironment interactions of small cell lung cancer. 

    E-Print Network [OSTI]

    Hodkinson, Philip Simon

    2009-01-01

    Small cell lung cancer (SCLC) is characterised by rapid growth, early metastatic spread and poor long-term survival. The tumour is initially sensitive to chemotherapy and thus objective response rates are high. Unfortunately, ...

  19. Functional lung imaging in humans using Positron Emission Tomography

    E-Print Network [OSTI]

    Layfield, Dominick, 1971-

    2003-01-01

    This thesis deals with a method of functional lung imaging using Positron Emission Tomography (PET). In this technique, a radioactive tracer, nitrogen-13, is dissolved in saline solution, and injected into a peripheral ...

  20. Selectins Mediate Small Cell Lung Cancer Systemic Metastasis

    E-Print Network [OSTI]

    Heidemann, Franziska

    Metastasis formation is the major reason for the extremely poor prognosis in small cell lung cancer (SCLC) patients. The molecular interaction partners regulating metastasis formation in SCLC are largely unidentified, ...

  1. HIF-2? deletion promotes Kras-driven lung tumor development

    E-Print Network [OSTI]

    Jacks, Tyler E.

    Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide. The oxygen-sensitive hypoxia inducible factor (HIF) transcriptional regulators HIF-1? and HIF-2? are overexpressed in many human NSCLCs, ...

  2. Black Hole Thermodynamics and Electromagnetism

    E-Print Network [OSTI]

    Burra G. Sidharth

    2005-07-15

    We show a strong parallel between the Hawking, Beckenstein black hole Thermodynamics and electromagnetism: When the gravitational coupling constant transform into the electromagnetic coupling constant, the Schwarzchild radius, the Beckenstein temperature, the Beckenstein decay time and the Planck mass transform to respectively the Compton wavelength, the Hagedorn temperature, the Compton time and a typical elementary particle mass. The reasons underlying this parallalism are then discussed in detail.

  3. Quantum chaos inside Black Holes

    E-Print Network [OSTI]

    Addazi, Andrea

    2015-01-01

    We show how semiclassical black holes can be reinterpreted as an effective geometry, composed of a large ensamble of horizonless naked singularities (eventually smoothed at the Planck scale). We call this new items {\\it frizzyballs}, which can be rigorously defined by euclidean path integral approach. This has interesting implications regarding information paradoxes. We demonstrate that infalling information will chaotically propagate inside this system before going to the full quantum gravity regime (Planck scale).

  4. Quantum chaos inside Black Holes

    E-Print Network [OSTI]

    Andrea Addazi

    2015-08-30

    We show how semiclassical black holes can be reinterpreted as an effective geometry, composed of a large ensamble of horizonless naked singularities (eventually smoothed at the Planck scale). We call this new items {\\it frizzyballs}, which can be rigorously defined by euclidean path integral approach. This has interesting implications regarding information paradoxes. We demonstrate that infalling information will chaotically propagate inside this system before going to the full quantum gravity regime (Planck scale).

  5. Classical Black Holes Are Hot

    E-Print Network [OSTI]

    Erik Curiel

    2014-11-09

    In the early 1970s it is was realized that there is a striking formal analogy between the Laws of black-hole mechanics and the Laws of classical thermodynamics. Before the discovery of Hawking radiation, however, it was generally thought that the analogy was only formal, and did not reflect a deep connection between gravitational and thermodynamical phenomena. It is still commonly held that the surface gravity of a stationary black hole can be construed as a true physical temperature and its area as a true entropy only when quantum effects are taken into account; in the context of classical general relativity alone, one cannot cogently construe them so. Does the use of quantum field theory in curved spacetime offer the only hope for taking the analogy seriously? I think the answer is `no'. To attempt to justify that answer, I shall begin by arguing that the standard argument to the contrary is not physically well founded, and in any event begs the question. Looking at the various ways that the ideas of "temperature" and "entropy" enter classical thermodynamics then will suggest arguments that, I claim, show the analogy between classical black-hole mechanics and classical thermodynamics should be taken more seriously, without the need to rely on or invoke quantum mechanics. In particular, I construct an analogue of a Carnot cycle in which a black hole "couples" with an ordinary thermodynamical system in such a way that its surface gravity plays the role of temperature and its area that of entropy. Thus, the connection between classical general relativity and classical thermodynamics on their own is already deep and physically significant, independent of quantum mechanics.

  6. Relationship of Black Holes to Bulges

    E-Print Network [OSTI]

    David Merritt; Laura Ferrarese

    2001-07-08

    Supermassive black holes appear to be uniquely associated with galactic bulges. The mean ratio of black hole mass to bulge mass was until recently very uncertain, with ground based, stellar kinematical data giving a value roughly an order of magnitude larger than other techniques. The discrepancy was resolved with the discovery of the M-sigma relation, which simultaneously established a tight corrrelation between black hole mass and bulge velocity dispersion, and confirmed that the stellar kinematical mass estimates were systematically too large due to failure to resolve the black hole's sphere of influence. There is now excellent agreement between the various techniques for estimating the mean black hole mass, including dynamical mass estimation in quiescent galaxies; reverberation mapping in active galaxies and quasars; and computation of the mean density of compact objects based on integrated quasar light. Implications of the M-sigma relation for the formation of black holes are discussed.

  7. Boson shells harboring charged black holes

    SciTech Connect (OSTI)

    Kleihaus, Burkhard; Kunz, Jutta; Laemmerzahl, Claus; List, Meike

    2010-11-15

    We consider boson shells in scalar electrodynamics coupled to Einstein gravity. The interior of the shells can be empty space, or harbor a black hole or a naked singularity. We analyze the properties of these types of solutions and determine their domains of existence. We investigate the energy conditions and present mass formulae for the composite black hole-boson shell systems. We demonstrate that these types of solutions violate black hole uniqueness.

  8. Thermodynamic fluctuation in black string flow

    E-Print Network [OSTI]

    Meng Sun; Yong-Chang Huna

    2015-06-14

    It has long been noticed that Laudau-Lifshitz theory can be used to study the fluctuation of a system that contains a black hole. Since the black string can be constructed by extending n-dimensional black hole into one extra dimension. We study the fluctuation of black string flow with a Schwarzschlid-like metric in D=n+1 dimensional spacetime and a charged solution in D=5 dimensional spacetime and get the second moments of the fluctuation of the mass flux and charge flux.

  9. Thermodynamic fluctuation in black string flow

    E-Print Network [OSTI]

    Meng Sun; Yong-Chang Huang

    2015-05-11

    It has long been noticed that Laudau-Lifshitz theory can be used to study the fluctuation of a system that contains a black hole. Since the black string can be constructed by extending n-dimensional black hole into one extra dimension. We study the fluctuation of black string flow with a Schwarzschlid-like metric in D=n+1 dimensional spacetime and a charged solution in D=5 dimensional spacetime and get the second moments of the fluctuation of the mass flux and charge flux.

  10. Black carbon contribution to global warming

    SciTech Connect (OSTI)

    Chylek, P.; Johnson, B.; Kou, L.; Wong, J.

    1996-12-31

    Before the onset of industrial revolution the only important source of black carbon in the atmosphere was biomass burning. Today, black carbon production is divided between the biomass and fossil fuel burning. Black carbon is a major agent responsible for absorption of solar radiation by atmospheric aerosols. Thus black carbon makes other aerosols less efficient in their role of reflecting solar radiation and cooling the earth-atmosphere system. Black carbon also contributes to the absorption of solar radiation by clouds and snow cover. The authors present the results of black carbon concentrations measurements in the atmosphere, in cloud water, in rain and snow melt water collected during the 1992--1996 time period over the southern Nova Scotia. Their results are put into the global and historical perspective by comparing them with the compilation of past measurements at diverse locations and with their measurements of black carbon concentrations in the Greenland and Antarctic ice cores. Black carbon contribution to the global warming is estimated, and compared to the carbon dioxide warming, using the radiative forcing caused by the black carbon at the top of the atmosphere.

  11. Lower Dimensional Black Holes: Inside and Out

    E-Print Network [OSTI]

    R. B. Mann

    1995-01-27

    I survey the physics of black holes in two and three spacetime dimensions, with special attention given to an understanding of their exterior and interior properties.

  12. Black Holes: from Speculations to Observations

    E-Print Network [OSTI]

    Thomas W. Baumgarte

    2006-04-13

    This paper provides a brief review of the history of our understanding and knowledge of black holes. Starting with early speculations on ``dark stars'' I discuss the Schwarzschild "black hole" solution to Einstein's field equations and the development of its interpretation from "physically meaningless" to describing the perhaps most exotic and yet "most perfect" macroscopic object in the universe. I describe different astrophysical black hole populations and discuss some of their observational evidence. Finally I close by speculating about future observations of black holes with the new generation of gravitational wave detectors.

  13. Rotating Black Holes and Coriolis Effect

    E-Print Network [OSTI]

    Wu, Xiaoning; Yuan, Pei-Hung; Cho, Chia-Jui

    2015-01-01

    In this work, we consider the fluid/gravity correspondence for general rotating black holes. By using the Petrov-like boundary condition in near horizon limit, we study the correspondence between gravitational perturbation and fluid equation. We find that the dual fluid equation for rotating black holes contains a Coriolis force term, which is closely related to the angular velocity of the black hole horizon. This can be seen as a dual effect for the frame-dragging effect of rotating black hole under the holographic picture.

  14. Rotating Black Holes and Coriolis Effect

    E-Print Network [OSTI]

    Xiaoning Wu; Yi Yang; Pei-Hung Yuan; Chia-Jui Cho

    2015-11-27

    In this work, we consider the fluid/gravity correspondence for general rotating black holes. By using the Petrov-like boundary condition in near horizon limit, we study the correspondence between gravitational perturbation and fluid equation. We find that the dual fluid equation for rotating black holes contains a Coriolis force term, which is closely related to the angular velocity of the black hole horizon. This can be seen as a dual effect for the frame-dragging effect of rotating black hole under the holographic picture.

  15. Design considerations for vehicular modifications to accommodate the disabled driver 

    E-Print Network [OSTI]

    Swarts, Albert Edwin

    1973-01-01

    , et al . , 1968) . One system called for a guidance wire buried in the highway with sensors installed in the car. This system was aimed mainly at freeway safety for the total driving population. The advantages of such a system to the disabled... would be licensed if he could pass the driving test with his equipment installed in the car. The safety of the assistive equipment has not been satisfac- torily determined (Hymen, 1973) . The Veterans Administration is trying, at this time...

  16. L.A. Rebellion: Creating a New Black Cinema

    E-Print Network [OSTI]

    Sheppard, Samantha Noelle

    2011-01-01

    Creating a New Black Cinema Symposium Review by SamanthaCreating a New Black Cinema By the turn of the next century,in the development of Black cinema took place at UCLA in the

  17. Queering Black Gay Historiography: Performance, (Mis) Identifications, and Possibilities

    E-Print Network [OSTI]

    Fitzgerald, Thomas Howard

    2013-01-01

    In 1976 the black comedy Car Wash featured a black gay manthe a openly black sissy in the Car Wash as a character thatsaw the distribution of Car Wash with Antoino Fargas playing

  18. Extraordinary vacuum black string solutions

    SciTech Connect (OSTI)

    Kim, Hyeong-Chan; Lee, Jungjai

    2008-01-15

    In addition to the boosted static solution there are two other classes of stationary stringlike solutions of the vacuum Einstein equation in (4+1) dimensions. Each class is characterized by three parameters of mass, tension, and momentum flow along the fifth coordinate. We analyze the metric properties of one of the two classes, which was previously assumed to be naked singular, and show that the solution spectrum contains black string and wormhole in addition to the known naked singularity as the momentum flow to mass ratio increases. Interestingly, there does not exist new zero momentum solution in these cases.

  19. Figure 6: An MTAH for 11 lung tumor contours generated by MDISC based on area, circularity, and extrusiveness.

    E-Print Network [OSTI]

    California at Los Angeles, University of

    Figure 6: An MTAH for 11 lung tumor contours generated by M­DISC based on area, circularity, and extrusiveness. Figure 7: The CT scanned lung image for image 6 (in Figure 3) with the lung tumor contour

  20. Effective theories and black hole production in warped compactificatio...

    Office of Scientific and Technical Information (OSTI)

    Effective theories and black hole production in warped compactifications Citation Details In-Document Search Title: Effective theories and black hole production in warped...

  1. SU-E-J-185: Gated CBCT Imaging for Positioning Moving Lung Tumor in Lung SBRT Treatment

    SciTech Connect (OSTI)

    Li, X; Li, T; Zhang, Y; Burton, S; Karlovits, B; Clump, D; Heron, D; Huq, M

    2014-06-01

    Purpose: Lung stereo-tactic body radiotherapy(SBRT) treatment requires high accuracy of lung tumor positioning during treatment, which is usually accomplished by free breathing Cone-Beam computerized tomography (CBCT) scan. However, respiratory motion induced image artifacts in free breathing CBCT may degrade such positioning accuracy. The purpose of this study is to investigate the feasibility of gated CBCT imaging for lung SBRT treatment. Methods: Six Lung SBRT patients were selected for this study. The respiratory motion of the tumors ranged from 1.2cm to 3.5cm, and the gating windows for all patients were set between 35% and 65% of the respiratory phases. Each Lung SBRT patient underwent free-breathing CBCT scan using half-fan scan technique. The acquired projection images were transferred out for off-line analyses. An In-house semi-automatic algorithm was developed to trace the diaphragm movement from those projection images to acquire a patient's specific respiratory motion curve, which was used to correlate respiratory phases with each projection image. Afterwards, a filtered back-projection algorithm was utilized to reconstruct the gated CBCT images based on the projection images only within the gating window. Results: Target volumes determined by free breathing CBCT images were 71.9%±72% bigger than the volume shown in gated CBCT image. On the contrary, the target volume differences between gated CBCT and planning CT images at exhale stage were 5.8%±2.4%. The center to center distance of the targets shown in free breathing CBCT and gated CBCT images were 9.2±8.1mm. For one particular case, the superior boundary of the target was shifted 15mm between free breathing CBCT and gated CBCT. Conclusion: Gated CBCT imaging provides better representation of the moving lung tumor with less motion artifacts, and has the potential to improve the positioning accuracy in lung SBRT treatment.

  2. The impact of education in shaping lives: reflections of young people with disabilities in Ghana

    E-Print Network [OSTI]

    Singal, Nidhi; Salifu, Edward Mahama; Iddrisu, Khadijatu; Casely-Hayford, Leslie; Lundebye, Helen

    2015-03-11

    employees with disabilities. Furthermore, they noted that most Ghanaians tend to ‘admire disable people who engage in productive activities and view those who resort to begging as a source of work as lazy and indeed ‘disabled’’ (p. 58). Given... with opportunities to make a positive contribution to society. Abbink, J. 2005. Being young in Africa: the politics of despair and renewal. Retrieved from: https://openaccess.leidenuniv.nl/bitstream/handle/1887/9608/ASC_1242160_167.pdf? sequence=1...

  3. An electromagnetic black hole made of metamaterials

    E-Print Network [OSTI]

    Qiang Cheng; Tie Jun Cui; Wei Xiang Jiang; Ben Geng Cai

    2010-04-30

    Traditionally, a black hole is a region of space with huge gravitational field, which absorbs everything hitting it. In history, the black hole was first discussed by Laplace under the Newton mechanics, whose event horizon radius is the same as the Schwarzschild's solution of the Einstein's vacuum field equations. If all those objects having such an event horizon radius but different gravitational fields are called as black holes, then one can simulate certain properties of the black holes using electromagnetic fields and metamaterials due to the similar propagation behaviours of electromagnetic waves in curved space and in inhomogeneous metamaterials. In a recent theoretical work by Narimanov and Kildishev, an optical black hole has been proposed based on metamaterials, in which the theoretical analysis and numerical simulations showed that all electromagnetic waves hitting it are trapped and absorbed. Here we report the first experimental demonstration of such an electromagnetic black hole in the microwave frequencies. The proposed black hole is composed of non-resonant and resonant metamaterial structures, which can trap and absorb electromagnetic waves coming from all directions spirally inwards without any reflections due to the local control of electromagnetic fields and the event horizon corresponding to the device boundary. It is shown that the absorption rate can reach 99% in the microwave frequencies. We expect that the electromagnetic black hole could be used as the thermal emitting source and to harvest the solar light.

  4. Black holes cannot support conformal scalar hair

    E-Print Network [OSTI]

    T. Zannias

    1994-09-14

    It is shown that the only static asymptotically flat non-extrema black hole solution of the Einstein-conformally invariant scalar field equations having the scalar field bounded on the horizon, is the Schwarzschild one. Thus black holes cannot be endowed with conformal scalar hair of finite length.

  5. Quantum Entropy of Charged Rotating Black Holes

    E-Print Network [OSTI]

    R. B. Mann

    1996-07-10

    I discuss a method for obtaining the one-loop quantum corrections to the tree-level entropy for a charged Kerr black hole. Divergences which appear can be removed by renormalization of couplings in the tree-level gravitational action in a manner similar to that for a static black hole.

  6. Topological Black Holes in Quantum Gravity

    E-Print Network [OSTI]

    J. Kowalski-Glikman; D. Nowak-Szczepaniak

    2000-07-31

    We derive the black hole solutions with horizons of non-trivial topology and investigate their properties in the framework of an approach to quantum gravity being an extension of Bohm's formulation of quantum mechanics. The solutions we found tend asymptotically (for large $r$) to topological black holes. We also analyze the thermodynamics of these space-times.

  7. Primordial black holes and asteroid danger

    E-Print Network [OSTI]

    Alexander Shatskiy

    2008-02-21

    Probability for a primordial black hole to invade the Kuiper belt was calculated. We showed that primordial black holes of certain masses can significantly change asteroids' orbits. These events may result in disasters, local for our solar system and global for the Earth (like the Tunguska meteorite). We also estimated how often such events occur.

  8. Stability of AdS black strings

    E-Print Network [OSTI]

    T. Delsate

    2008-08-14

    We review the recent developements in the stability problem and phase diagram for asymptotically locally $AdS$ black strings. First, we quickly review the case of locally flat black string before turning to the case of locally $AdS$ spacetimes.

  9. Canonical structure of 2D black holes

    E-Print Network [OSTI]

    Navarro-Salas, J; Talavera, C F

    1994-01-01

    We determine the canonical structure of two-dimensional black-hole solutions arising in $2D$ dilaton gravity. By choosing the Cauchy surface appropriately we find that the canonically conjugate variable to the black hole mass is given by the difference of local (Schwarzschild) time translations at right and left spatial infinities. This can be regarded as a generalization of Birkhoff's theorem.

  10. Fractal Statistics and Quantum Black Hole Entropy

    E-Print Network [OSTI]

    Wellington da Cruz

    2000-11-18

    Simple considerations about the fractal characteristic of the quantum-mechanical path give us the opportunity to derive the quantum black hole entropy in connection with the concept of fractal statistics. We show the geometrical origin of the numerical factor of four of the quantum black hole entropy expression and the statistics weight appears as a counting of the quanta of geometry.

  11. Can Superconducting Cosmic Strings Piercing Seed Black Holes Generate Supermassive Black Holes in the Early Universe?

    E-Print Network [OSTI]

    Lake, Matthew J

    2015-01-01

    The discovery of a large number of supermassive black holes at redshifts $z> 6$, when the Universe was only nine hundred million years old, has raised the fundamental question of how such massive compact objects could form in a (cosmologically) short time interval. Each of the proposed standard scenarios for black hole formation, involving rapid accretion of seed black holes, or black hole mergers, faces severe theoretical difficulties in explaining the short time formation of supermassive objects. In the present Letter, we propose an alternative scenario for the formation of supermassive black holes in the early Universe in which energy transfer from superconducting cosmic strings, piercing small seed black holes, is the main physical process leading to rapid mass increase. The increase in mass of a primordial seed black hole pierced by two antipodal strings is estimated and it is shown that this increases linearly in time. Due to the high energy transfer rate from the cosmic strings, we find that supermassi...

  12. Class Transitions in Black Holes

    E-Print Network [OSTI]

    Sandip K. Chakrabarti

    2005-01-14

    A black hole spectrum is known to change from the hard state to the soft state when the energy spectral index $\\alpha$ ($F_E \\propto E^{-\\alpha}$) in, say, 2-20 keV range changes from $\\alpha \\sim 0.5$ to $\\sim 1.5$. However, this `classical' definition which characterizes black holes like Cyg X-1, becomes less useful for many objects such as GRS 1915+105 in which the spectral slope is seen to vary from one to the other in a matter of seconds and depending on whether or not winds form, the spectral slope also changes. The light curves and the colour-colour diagrams may look completely different on different days depending on the frequency and mode of switching from one spectral state to the other. Though RXTE observations have yielded wealth of information on such `variability classes' in GRS 1915+105, very rarely one has been able to observe how the object goes from one class to the other. In the present review, we discuss possible origins of the class transition and present several examples of such transitions. In this context, we use mostly the results of the Indian X-ray Astronomy Experiment (IXAE) which observed GRS 1915+105 more regularly.

  13. Nonthermal correction to black hole spectroscopy

    E-Print Network [OSTI]

    Wen-Yu Wen

    2014-11-14

    Area spectrum of black holes have been obtained via various methods such as quasinormal modes, adiabatic invariance and angular momentum. Among those methods, calculations were done by assuming black holes in thermal equilibrium. Nevertheless, black holes in the asymptotically flat space usually have negative specific heat and therefore tend to stay away from thermal equilibrium. Even for those black holes with positive specific heat, temperature may still not be well defined in the process of radiation, due to the back reaction of decreasing mass. Respect to these facts, it is very likely that Hawking radiation is nonthermal and the area spectrum is no longer equidistant. In this note, we would like to illustrate how the area spectrum of black holes is corrected by this nonthermal effect.

  14. Fourier Analysis of the BTZ Black Hole

    E-Print Network [OSTI]

    Ian M. Tolfree

    2009-11-11

    In this paper we extend our previous work regarding the role of the Fourier transformation in bulk to boundary mappings to include the BTZ black hole. We follow standard procedures for modifying Fourier Transformations to accommodate quotient spaces and arrive at a bulk to boundary mapping in a black hole background. We show that this mapping is consistent with known results and lends a new insight into the AdS/CFT duality. We find that the micro-states corresponding to the entropy of a bulk scalar field are the Fourier coefficients on the boundary, which transform under the principal series representation of $SL(2,R)$. Building upon this we present a toy model to analyze the implications of this for the origin of black hole entropy. We find that the black hole micro-states live on the boundary and correspond to the possible emission modes of the black hole

  15. Evidence for the Black Hole Event Horizon

    E-Print Network [OSTI]

    Ramesh Narayan

    2003-10-23

    Astronomers have discovered many candidate black holes in X-ray binaries and in the nuclei of galaxies. The candidate objects are too massive to be neutron stars, and for this reason they are considered to be black holes. While the evidence based on mass is certainly strong, there is no proof yet that any of the objects possesses the defining characteristic of a black hole, namely an event horizon. Type I X-ray bursts, which are the result of thermonuclear explosions when gas accretes onto the surface of a compact star, may provide important evidence in this regard. Type I bursts are commonly observed in accreting neutron stars, which have surfaces, but have never been seen in accreting black hole candidates. It is argued that the lack of bursts in black hole candidates is compelling evidence that these objects do not have surfaces. The objects must therefore possess event horizons.

  16. How fast can a black hole rotate?

    E-Print Network [OSTI]

    Herdeiro, Carlos A R

    2015-01-01

    Kerr black holes have their angular momentum, $J$, bounded by their mass, $M$: $Jc\\leqslant GM^2$. There are, however, known black hole solutions violating this Kerr bound. We propose a very simple universal bound on the rotation, rather than on the angular momentum, of four-dimensional, stationary and axisymmetric, asymptotically flat black holes, given in terms of an appropriately defined horizon linear velocity, $v_H$. The $v_H$ bound is simply that $v_H$ cannot exceed the velocity of light. We verify the $v_H$ bound for known black hole solutions, including some that violate the Kerr bound, and conjecture that only extremal Kerr black holes saturate the $v_H$ bound.

  17. Classification of interstitial lung disease patterns with topological texture features

    E-Print Network [OSTI]

    Huber, Markus B; Leinsinger, Gerda; Ray, Lawrence A; Wismüller, Axel; 10.1117/12.844318

    2010-01-01

    Topological texture features were compared in their ability to classify morphological patterns known as 'honeycombing' that are considered indicative for the presence of fibrotic interstitial lung diseases in high-resolution computed tomography (HRCT) images. For 14 patients with known occurrence of honey-combing, a stack of 70 axial, lung kernel reconstructed images were acquired from HRCT chest exams. A set of 241 regions of interest of both healthy and pathological (89) lung tissue were identified by an experienced radiologist. Texture features were extracted using six properties calculated from gray-level co-occurrence matrices (GLCM), Minkowski Dimensions (MDs), and three Minkowski Functionals (MFs, e.g. MF.euler). A k-nearest-neighbor (k-NN) classifier and a Multilayer Radial Basis Functions Network (RBFN) were optimized in a 10-fold cross-validation for each texture vector, and the classification accuracy was calculated on independent test sets as a quantitative measure of automated tissue characteriza...

  18. Developmental expression and glucocorticoid control of the leptin receptor in fetal ovine lung

    E-Print Network [OSTI]

    De Blasio, Miles J.; Boije, Maria; Vaughan, Owen R.; Bernstein, Brett S.; Davies, Katie L.; Plein, Alice; Kempster, Sarah L.; Smith, Gordon C. S.; Charnock-Jones, D. Stephen; Blache, Dominique; Wooding, F. B. Peter; Giussani, Dino A.; Fowden, Abigail L.; Forhead, Alison J.

    2015-08-11

    The effects of endogenous and synthetic glucocorticoids on fetal lung maturation are well-established, although the role of leptin in lung development before birth is unclear. This study examined mRNA and protein levels of the signalling long...

  19. Response and Resistance to NF-?B Inhibitors in Mouse Models of Lung Adenocarcinoma

    E-Print Network [OSTI]

    Xue, Wen

    Lung adenocarcinoma is a leading cause of cancer death worldwide. We recently showed that genetic inhibition of the NF-?B pathway affects both the initiation and the maintenance of lung cancer, identifying this pathway as ...

  20. Spatiotemporal quantification of cell dynamics in the lung following influenza virus infection

    E-Print Network [OSTI]

    Yin, Lu

    Lung injury caused by influenza virus infection is widespread. Understanding lung damage and repair progression post infection requires quantitative spatiotemporal information on various cell types mapping into the tissue ...

  1. Precision-cut lung slices: a novel model for respiratory tract toxicology 

    E-Print Network [OSTI]

    Schwade, Lisa Schier

    1995-01-01

    The lungs are a prominent target organ for numerous types of chemically-induced pathological changes. Current concepts of the pathogenesis of lung injury and repair are derived from in vitro and in vivo investigations. In ...

  2. Major Shifts in the Spatio-Temporal Distribution of Lung Antioxidant Enzymes during Influenza Pneumonia

    E-Print Network [OSTI]

    Yamada, Yoshiyuki

    With the incessant challenge of exposure to the air we breathe, lung tissue suffers the highest levels of oxygen tension and thus requires robust antioxidant defenses. Furthermore, following injury or infection, lung tissue ...

  3. Telomere Length in Circulating Leukocytes Is Associated with Lung Function and Disease

    E-Print Network [OSTI]

    Nyholt, Dale R.

    Telomere Length in Circulating Leukocytes Is Associated with Lung Function and Disease Eva Albrecht. Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research, Munich, Germany

  4. Journal of Biomechanics 40 (2007) 9931001 Pulmonary vascular remodeling in isolated mouse lungs

    E-Print Network [OSTI]

    Chesler, Naomi C.

    2007-01-01

    Journal of Biomechanics 40 (2007) 993­1001 Pulmonary vascular remodeling in isolated mouse lungs­flow relationships in mouse lungs and does so via structural remodeling. They also provide important baseline data

  5. Evaluation of Force Feedback Requirements for Minimally Invasive Lung Tumour Localization

    E-Print Network [OSTI]

    Naish, Michael D.

    Evaluation of Force Feedback Requirements for Minimally Invasive Lung Tumour Localization Greig L describes experiments that were conducted on ex-vivo porcine lung, using artificial tumours, to elucidate

  6. Program restructuring using clustering techniques Chung-Horng Lung a,*, Xia Xu a

    E-Print Network [OSTI]

    Lung, Chung-Horng

    Program restructuring using clustering techniques Chung-Horng Lung a,*, Xia Xu a , Marzia Zaman b. Tel.: +1 613 5202600; fax: +1 613 5205727. E-mail addresses: chlung@sce.carleton.ca (C.-H. Lung

  7. Quantification of Neuroepithelial Bodies and Their Innervation in Fawn-Hooded and Wistar Rat Lungs

    E-Print Network [OSTI]

    Burnstock, Geoffrey

    Quantification of Neuroepithelial Bodies and Their Innervation in Fawn-Hooded and Wistar Rat Lungs neuroendocrine system (DNES) of the lungs, the neuroendocrine cells of which have been shown to express

  8. On Computing Farthest Dominated Locations Hua Lu, Member, IEEE, Man Lung Yiu

    E-Print Network [OSTI]

    Yiu, Man Lung

    1 On Computing Farthest Dominated Locations Hua Lu, Member, IEEE, Man Lung Yiu Abstract--In reality@cs.aau.dk · Man Lung Yiu is with the Department of Computing, Hong Kong Polytechnic University, Hong Kong. E

  9. Smarter Electricity through Argumentation Menelaos Makriyiannis, Tudor Lung, Robert Craven, Francesca Toni and Jack Kelly

    E-Print Network [OSTI]

    Toni, Francesca

    Smarter Electricity through Argumentation Menelaos Makriyiannis, Tudor Lung, Robert Craven101,ft,dk3810}@doc.ic.ac.uk, tudor.lung@gmail.com Abstract--The current, widespread introduction

  10. Reverse Nearest Neighbors Search in Ad-hoc Subspaces Man Lung Yiu

    E-Print Network [OSTI]

    Mamoulis, Nikos

    Reverse Nearest Neighbors Search in Ad-hoc Subspaces Man Lung Yiu Department of Computer Science, H.2.4.h Query processing, H.2.4.k Spatial databases Contact Author: Man Lung Yiu Department

  11. Software Architecture Decomposition Using Attributes Chung-Horng Lung, Xia Xu Marzia Zaman

    E-Print Network [OSTI]

    Lung, Chung-Horng

    Software Architecture Decomposition Using Attributes Chung-Horng Lung, Xia Xu Marzia Zaman in the life cycle. Inspired by Alexander, Andreu, et al. [3] and Lung, et al. [15] presented applications

  12. Extracting k Most Important Groups from Data Efficiently Man Lung Yiu a

    E-Print Network [OSTI]

    Hristidis, Vagelis

    Extracting k Most Important Groups from Data Efficiently Man Lung Yiu a , Nikos Mamoulis b.3 Optimization and Performance Contact Author: Man Lung Yiu #12;1. Introduction Aggregate queries summarize

  13. Residential radon and lung cancer incidence in a Danish cohort

    SciTech Connect (OSTI)

    Braeuner, Elvira V., E-mail: ole@cancer.dk [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Danish Building Research Institute, Aalborg University (Denmark); Andersen, Claus E. [Center for Nuclear Technologies, Radiation Research Division, Riso National Laboratory for Sustainable Energy, Technical University of Denmark, Roskilde (Denmark)] [Center for Nuclear Technologies, Radiation Research Division, Riso National Laboratory for Sustainable Energy, Technical University of Denmark, Roskilde (Denmark); Sorensen, Mette [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Jovanovic Andersen, Zorana [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark) [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Center for Epidemiology Screening, Department of Public Health, University of Copenhagen (Denmark); Gravesen, Peter [Geological Survey of Denmark and Greenland, Copenhagen (Denmark)] [Geological Survey of Denmark and Greenland, Copenhagen (Denmark); Ulbak, Kaare [National Institute of Radiation Protection, Herlev (Denmark)] [National Institute of Radiation Protection, Herlev (Denmark); Hertel, Ole [Department of Environmental Science, Aarhus University, Aarhus (Denmark)] [Department of Environmental Science, Aarhus University, Aarhus (Denmark); Pedersen, Camilla [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark); Overvad, Kim [Department of Epidemiology, School of Public Health, Aarhus University, Aarhus (Denmark)] [Department of Epidemiology, School of Public Health, Aarhus University, Aarhus (Denmark); Tjonneland, Anne; Raaschou-Nielsen, Ole [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)] [Diet, Genes and Environment, Danish Cancer Society Research Centre, Copenhagen (Denmark)

    2012-10-15

    High-level occupational radon exposure is an established risk factor for lung cancer. We assessed the long-term association between residential radon and lung cancer risk using a prospective Danish cohort using 57,053 persons recruited during 1993-1997. We followed each cohort member for cancer occurrence until 27 June 2006, identifying 589 lung cancer cases. We traced residential addresses from 1 January 1971 until 27 June 2006 and calculated radon at each of these addresses using information from central databases regarding geology and house construction. Cox proportional hazards models were used to estimate incidence rate ratios (IRR) and 95% confidence intervals (CI) for lung cancer risk associated with residential radon exposure with and without adjustment for sex, smoking variables, education, socio-economic status, occupation, body mass index, air pollution and consumption of fruit and alcohol. Potential effect modification by sex, traffic-related air pollution and environmental tobacco smoke was assessed. Median estimated radon was 35.8 Bq/m{sup 3}. The adjusted IRR for lung cancer was 1.04 (95% CI: 0.69-1.56) in association with a 100 Bq/m{sup 3} higher radon concentration and 1.67 (95% CI: 0.69-4.04) among non-smokers. We found no evidence of effect modification. We find a positive association between radon and lung cancer risk consistent with previous studies but the role of chance cannot be excluded as these associations were not statistically significant. Our results provide valuable information at the low-level radon dose range.

  14. SU-E-T-351: Verification of Monitor Unit Calculation for Lung...

    Office of Scientific and Technical Information (OSTI)

    States Language: English Subject: 60 APPLIED LIFE SCIENCES; COMPUTERIZED TOMOGRAPHY; LUNGS; MONTE CARLO METHOD; RADIATION DOSES; RADIATION MONITORS; RADIOTHERAPY; SPATIAL...

  15. SU-F-BRE-07: Experimental Validation of a Lung SBRT Technique...

    Office of Scientific and Technical Information (OSTI)

    of Publication: United States Language: English Subject: 60 APPLIED LIFE SCIENCES; LUNGS; PATIENTS; PHANTOMS; PLANNING; PLASTICS; RADIATION DOSE DISTRIBUTIONS; RADIATION...

  16. Pulmonary Artery Pseudoaneurysm Related to Radiofrequency Ablation of Lung Tumor

    SciTech Connect (OSTI)

    Sakurai, Jun, E-mail: sakurai@cc.okayama-u.ac.jp; Mimura, Hidefumi; Gobara, Hideo; Hiraki, Takao; Kanazawa, Susumu [Okayama University Medical School, Department of Radiology (Japan)

    2010-04-15

    We describe a case of pulmonary artery (PA) pseudoaneurysm related to radiofrequency ablation (RFA) of lung tumor. We performed RFA for a pulmonary epithelioid hemangioendothelioma directly adjacent to a branch of the PA. Seventeen days later, the patient complained of hemoptysis. A chest CT image revealed PA pseudoaneurysm. Transcatheter coil embolization was performed 59 days after RFA. Although PA pseudoaneurysm is rare, with an incidence of 0.2% (1/538 sessions) at our institution, it should be recognized as a risk when treating lung tumors adjacent to a branch of the PA.

  17. Perfusion lung scan: an aid in detection of lymphangitic carcinomatosis

    SciTech Connect (OSTI)

    Bates, S.E.; Tranum, B.L.

    1982-07-15

    Lymphangitic carcinomatosis is usually a late manifestation of metastatic disease. The patient usually presents with cough or dyspnea, and the chest radiograph is often nondiagnostic. Two patients are presented who developed symptoms while on adjuvant chemotherapy. Both had abnormal perfusion lung scans. One had matching ventilation defects; the other a normal ventilation study. Biopsy revealed metastatic carcinoma; in one case tumor was seen in both the pulmonary lymphatics and arterioles; in the other, tumor was identified but the site could not be specified. The radionuclide lung scan is a technique which can speed diagnosis and institution of therapy in lymphangitic carcinomatosis.

  18. Relating Airway Diameter Distributions to Regular Branching Asymmetry in the Lung Arnab Majumdar,1,2

    E-Print Network [OSTI]

    Buldyrev, Sergey

    Relating Airway Diameter Distributions to Regular Branching Asymmetry in the Lung Arnab Majumdar,1 as a function of generation N in asymmetric airway trees of mammalian lungs. We find that the airway]. Most models of the lung airway tree either do not address the observed diameter heterogeneity or simply

  19. Scaling behavior in crackle sound during lung inflation Adriano M. Alencar,1,2

    E-Print Network [OSTI]

    Stanley, H. Eugene

    Scaling behavior in crackle sound during lung inflation Adriano M. Alencar,1,2 Zolta´n Hantos,3 received 14 July 1999 During slow inflation of lung lobes, we measure a sequence of short explosive are a consequence of structural heterogeneity in the lung, ii the intermittent behavior is due to the avalanchelike

  20. Fluid transport in branched structures with temporary closures: A model for quasistatic lung inflation

    E-Print Network [OSTI]

    Buldyrev, Sergey

    Fluid transport in branched structures with temporary closures: A model for quasistatic lung a model system relevant to the inflation of a mammalian lung, an asymmetric bifurcating structure description of the underlying branching structure of the lung, by analyzing experimental pressure-volume data

  1. Mechanical interactions between collagen and proteoglycans: implications for the stability of lung tissue

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Mechanical interactions between collagen and proteoglycans: implications for the stability of lung- tions for the stability of lung tissue. J Appl Physiol 98: 672­679, 2005. First published September 24- ticity of the connective tissue including lung parenchyma. The gly- cosaminoglycans on the proteoglycans

  2. Lung and alveolar wall elastic and hysteretic behavior in rats: effects of in vivo elastase treatment

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Lung and alveolar wall elastic and hysteretic behavior in rats: effects of in vivo elastase P. Ingenito, and Be´la Suki. Lung and alveolar wall elastic and hysteretic behavior in rats: effects behavior of the alveolar walls and the macroscopic mechanical properties of the whole lung in an in vivo

  3. -Actin: disposition, quantities, and estimated effects on lung recoil and compliance

    E-Print Network [OSTI]

    -Actin: disposition, quantities, and estimated effects on lung recoil and compliance E. H. OLDMIXON, Jr. -Actin: disposition, quantities, and estimated effects on lung recoil and compliance. J Appl by measuring dispo- sition and quantities of -smooth muscle actin in rat and guinea pig lungs and modeling its

  4. Physica A 357 (2005) 1826 Crackles and instabilities during lung inflation

    E-Print Network [OSTI]

    Stanley, H. Eugene

    2005-01-01

    Physica A 357 (2005) 18­26 Crackles and instabilities during lung inflation Adriano M. Alencara, called the ``active surface''. We define the active surface of the lung as the set of airway segments and open regions in a collapsed lung. To study the active surface and the time interval between consecutive

  5. Reduced xenon diffusion for quantitative lung studythe role of SF6

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Reduced xenon diffusion for quantitative lung studyÐthe role of SF6 Ross W. Mair,1 * Dominik in most NMR experiments. In restricted environments, such as the lung, this rapid gas diffusion can lead the development of lung ventilation MRI using laser-polarized noble gases (129 Xe and 3 He),1,2 attention has been

  6. Monte Carlo simulation of liquid bridge rupture: Application to lung physiology Adriano M. Alencar,1

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Monte Carlo simulation of liquid bridge rupture: Application to lung physiology Adriano M. Alencar of certain lung diseases, the surface properties and the amount of fluids coating the airways changes of similar bridges that exist in diseased lungs. DOI: 10.1103/PhysRevE.74.026311 PACS number s : 47.90 a, 04

  7. Line Narrowing of Fiber Coupled Laser Diode Array He Lung MRI

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Line Narrowing of Fiber Coupled Laser Diode Array and 3 He Lung MRI by Jermane E. Massey B Coupled Laser Diode Array and 3 He Lung MRI by Jermane E. Massey Submitted to the Department of PhysicsW of injected power. A novel MRI coil and polarization system were developed for hyper-polarized 3 He lung

  8. Posture-dependent Human 3He Lung Imaging in an Open-access MRI System

    E-Print Network [OSTI]

    Walsworth, Ronald L.

    Posture-dependent Human 3He Lung Imaging in an Open-access MRI System: Initial Results1 Leo L. Tsai. Walsworth, PhD Rationale and Objectives. The human lung and its functions are extremely sensitive in determining lung function and heterogeneity of perfusion and ventilation. However, study of these effects

  9. Shallow and Deep Lunge Feeding of Humpback Whales in Fjords of the West Antarctic Peninsula

    E-Print Network [OSTI]

    Ware, Colin

    1 Shallow and Deep Lunge Feeding of Humpback Whales in Fjords of the West Antarctic Peninsula Colin lunges during which they engulf large volumes of water equal to as much as 70% of their body mass. To understand the kinematics of humpback lunge feeding, we attached high-resolution digital recording tags

  10. Magnetomotive optical coherence elastography for relating lung structure and function in Cystic Fibrosis

    E-Print Network [OSTI]

    Oldenburg, Amy

    Magnetomotive optical coherence elastography for relating lung structure and function in Cystic and normal lung tissues using OCT and correlative study with histology is also examined. We also demonstrate changes in CF lung structure and function and the novel method of longitudinal in vitro ECM assessment

  11. Mathematical Modeling of the First Inflation of Degassed Lungs BELA SUKI,* JOSE S. ANDRADE, JR.,

    E-Print Network [OSTI]

    Stanley, H. Eugene

    Mathematical Modeling of the First Inflation of Degassed Lungs BE´LA SUKI,* JOSE´ S. ANDRADE, JR--The pressure­volume (P­V) relationship of de- gassed lungs during the first inflation is different from and degassed rabbit lungs. By fitting these data, we found that n 17 5, Plow 23 4 cmH2O

  12. Acoustic evidence of airway opening during recruitment in excised dog lungs Z. Hantos,1

    E-Print Network [OSTI]

    Alencar, Adriano Mesquita

    Acoustic evidence of airway opening during recruitment in excised dog lungs Z. Hantos,1 J. Tolnai,1. Majumdar, and B. Suki. Acoustic evidence of airway opening during recruitment in excised dog lungs. J Appl-volume curve in the normal lung are primarily determined by airway reopen- ings via avalanches rather than

  13. Massive Hemoptysis from Pulmonary Artery Pseudoaneurysm Caused by Lung Radiofrequency Ablation: Successful Treatment by Coil Embolization

    SciTech Connect (OSTI)

    Yamakado, Koichiro, E-mail: yama@clin.medic.mie-u.ac.jp; Takaki, Haruyuki [Mie University School of Medicine, Department of Radiology (Japan); Takao, Motoshi [Mie University School of Medicine, Department of Thoracic Surgery (Japan); Murashima, Shuichi; Kodama, Hiroshi; Kashima, Masataka; Nakatsuka, Atsuhiro; Uraki, Junji [Mie University School of Medicine, Department of Radiology (Japan); Shimpo, Hideto [Mie University School of Medicine, Department of Thoracic Surgery (Japan); Takeda, Kan [Mie University School of Medicine, Department of Radiology (Japan)

    2010-04-15

    A 75-year-old man received lung radiofrequency (RF) ablation to treat lung metastases from hepatocellular carcinoma. Massive hemoptysis occurred 1 week after lung RF ablation. Emergent contrast-enhanced CT and pulmonary arteriography revealed a pulmonary artery pseudoaneurysm, which was embolized with coils. The postembolization course was uneventful. Hemoptysis did not recur for 5 months.

  14. Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high

    E-Print Network [OSTI]

    Rodenacker, Karsten

    109 Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high resolution image tumours (NET) of the lung are divided in subtypes with different malignant potential. The first and worse prognosis indepen- dent of staging and tumour type. Keywords: Neuroendocrine lung tumours

  15. Asthma is a chronic inflammatory disease of the lungs that is increasingly observed in developed countries

    E-Print Network [OSTI]

    Cai, Long

    Asthma is a chronic inflammatory disease of the lungs that is increasingly observed in developed in the lungs. However, characteristic to both forms of the disease is the airway- wall accumulation of T helper are expressed either by skin8 or lung epithelial cells and can influence the way in which epithelial cells

  16. Circulation . Author manuscript Activation of lung p53 by Nutlin-3a prevents and reverses experimental

    E-Print Network [OSTI]

    Boyer, Edmond

    Circulation . Author manuscript Page /1 14 Activation of lung p53 by Nutlin-3a prevents PA-SMCs; lung p53, p21, and MDM2 protein levels; and p21, Bax, PUMA, BTG2, and MDM2 mRNA levels or reversal by Nutlin-3a required lung p53 stabilization and increased p21 expression, as indicated

  17. Volume Estimation and Surgery Planning from Lung CT Images ANA ELISA FERREIRA SCHMIDT

    E-Print Network [OSTI]

    Volume Estimation and Surgery Planning from Lung CT Images ANA ELISA FERREIRA SCHMIDT 1 , PAULO to assist the planning of lung reduction surgeries, a technique that has been proposed for the treatment of certain illnesses. Doctors need to decide which portions of the lungs to remove to achieve a certain

  18. RESEARCH Open Access Accuracy and precision of end-expiratory lung-

    E-Print Network [OSTI]

    RESEARCH Open Access Accuracy and precision of end-expiratory lung- volume measurements , Gilles Bernardin2 and Laurent Brochard1,9,10 Abstract Introduction: End-expiratory lung volume (EELV in lung volume above functional residual capacity measured with passive spirometry (PEEP

  19. Impact of axial diffusion on nitric oxide exchange in the lungs

    E-Print Network [OSTI]

    George, Steven C.

    Impact of axial diffusion on nitric oxide exchange in the lungs HYE-WON SHIN1 AND STEVEN C. GEORGE1, Hye-Won, and Steven C. George. Impact of axial diffusion on nitric oxide exchange in the lungs. J Appl of the lungs, but neglects axial diffusion. We incorporated axial diffusion into a one-dimensional trumpet

  20. Slit and robo: expression patterns in lung development Mark A. Anselmoa

    E-Print Network [OSTI]

    Wu, Jane Y.

    Slit and robo: expression patterns in lung development Mark A. Anselmoa , Sussie Dalvina , Parthak and elongation. Indirect evidence implicates Slit and Robo in lung development. We now demonstrate that Slit-2 and Slit-3 are developmentally regulated in embryonic murine lung. Immunohistochemistry demonstrates Slit-2

  1. CLARET: A Fast Deformable Registration Method Applied to Lung Radiation Therapy

    E-Print Network [OSTI]

    CLARET: A Fast Deformable Registration Method Applied to Lung Radiation Therapy Chen-Rui Chou1 and accurate image-guided radiother- apy in lung with low-dose imaging. CLARET contains three components: shape. At treatment time, CLARET computes a patient's lung deformations by iteratively apply- ing the learned

  2. A Framework for Unsupervised Segmentation of Lung Tissues from Low Dose Computed

    E-Print Network [OSTI]

    Kim, Tae-Kyun

    A Framework for Unsupervised Segmentation of Lung Tissues from Low Dose Computed Tomography Images of lung tis- sues from Low Dose Computed Tomography (LDCT) are proposed. In this paper we describe LDCT images and desired maps of regions (lung and the other chest tissues) by a joint Markov-Gibbs random

  3. The porcine lung as a potential model for cystic fibrosis Christopher S. Rogers,1

    E-Print Network [OSTI]

    Engelhardt, John F.

    Review The porcine lung as a potential model for cystic fibrosis Christopher S. Rogers,1 William M, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ. The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 295: L240­L263, 2008. First published May 16, 2008; doi:10

  4. A Distributed Biomarker Atlas for Lung Research aiding the Discovery and Early Detection of Cancer Biomarkers

    E-Print Network [OSTI]

    Mattmann, Chris

    A Distributed Biomarker Atlas for Lung Research aiding the Discovery and Early Detection of Cancer Atlas software system that allows a researcher to correlate lung cancer patients with similar characteristics around regions of the lung in which their sample specimens including multiple types

  5. STATISTICAL MODELING OF THE LUNG NODULES IN LOW DOSE COMPUTED TOMOGRAPHY SCANS OF THE CHEST

    E-Print Network [OSTI]

    Louisville, University of

    STATISTICAL MODELING OF THE LUNG NODULES IN LOW DOSE COMPUTED TOMOGRAPHY SCANS OF THE CHEST Amal in automatic detection of the lung nodules and is compared with respect to parametric nodule models in terms appearing in low dose CT (LDCT) scans of the human chest. Four types of common lung nodules are analyzed

  6. Modeling Respiratory Lung Motion a Biophysical Approach using Finite Element Methods

    E-Print Network [OSTI]

    Lübeck, Universität zu

    Modeling Respiratory Lung Motion ­ a Biophysical Approach using Finite Element Methods Rene Wernera motion gains in importance. In this paper a biophysical approach for modeling lung motion is described. Main aspects of the process of lung ventilation are identified and outlined as the starting point

  7. Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

    E-Print Network [OSTI]

    Frey, Brendan J.

    Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes provided information regarding the dynamics of gene expression during development of the mouse lung a global survey of protein expression during mouse lung organogenesis from embryonic day E13.5 until

  8. Modeling Alveolar Volume Changes During Periodic Breathing in Heterogeneously Ventilated Lungs

    E-Print Network [OSTI]

    Jeavons, Peter

    Modeling Alveolar Volume Changes During Periodic Breathing in Heterogeneously Ventilated Lungs SARA-uniform breathing pattern for a lung with an inhomogeneous gas distribution, such as that observed in some subjects of irregular breathing caused by small, poorly ventilated regions of the lung. Presented here is an extension

  9. Theoretical Gas Phase Mass Transfer Coefficients for Endogenous Gases in the Lungs

    E-Print Network [OSTI]

    George, Steven C.

    Theoretical Gas Phase Mass Transfer Coefficients for Endogenous Gases in the Lungs PETER CONDORELLI, is produced within the tissue of the airways of the lungs.16 As an intercellular messenger, NO is involved is available regarding the basic gas exchange dynamics of NO in the lungs. Ingested ethanol EtOH is transported

  10. Morphology of the Small-Animal Lung Using Magnetic Resonance Microscopy

    E-Print Network [OSTI]

    Morphology of the Small-Animal Lung Using Magnetic Resonance Microscopy Laurence W. Hedlund and G motion control and animal support, the lungs of the live, small animal can be imaged. Although in vivo He, it is possible to image the tissue and gas compartments of the lung. This capability

  11. Visualization of Density Variation in Lung Aristofanes C. Silva a,, Paulo Cezar P. Carvalho b

    E-Print Network [OSTI]

    Visualization of Density Variation in Lung Nodules Arist´ofanes C. Silva a,, Paulo Cezar P de Janeiro, RJ, Brazil Abstract We propose a method for visualize lung nodule, in order to emphasize submitted to Medical Image Analysis 27 May 2002 #12;1 Introduction Lung cancer is known to be the form

  12. Effet of Combined Nitrogen Dioxide and Carbon Nanoparticle Exposure on Lung Function During

    E-Print Network [OSTI]

    Boyer, Edmond

    Effet of Combined Nitrogen Dioxide and Carbon Nanoparticle Exposure on Lung Function During and Respiratory Medicine, Paediatric Lung Function Laboratory, Amiens University Hospital, Amiens, France, 3 and challenges in Borwn-Norway (BN) rat, in order to assess their interactions on lung function and airway

  13. Optimal Surface Marker Locations for Tumor Motion Estimation in Lung Cancer Radiotherapy

    E-Print Network [OSTI]

    Soatto, Stefano

    Optimal Surface Marker Locations for Tumor Motion Estimation in Lung Cancer Radiotherapy Bin Dong is a widely used approach in lung cancer radiotherapy. The purpose of this work is to propose an algorithm been tested on realistic clinical data of four lung cancer patients. Thoracic 4DCT scans with 10 phases

  14. Branching morphogenesis of the lung: new molecular insights into an old

    E-Print Network [OSTI]

    Chuang, Pao-Tien

    Branching morphogenesis of the lung: new molecular insights into an old problem Pao-Tien Chuang1 It has been known for decades that branching morpho- genesis of the lung is mediated through reciprocal between major signaling path- ways during branching morphogenesis of the lung in mice. It has been known

  15. The fractality of lung sounds: A comparison of three waveform fractal dimension algorithms

    E-Print Network [OSTI]

    Moussavi, Zahra M. K.

    The fractality of lung sounds: A comparison of three waveform fractal dimension algorithms January of flow-specific lung sounds (LS) have been compared to examine the fractal nature of these signals. LS between LS in health and disease. Ó 2005 Elsevier Ltd. All rights reserved. 1. Introduction Lung sounds

  16. Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using

    E-Print Network [OSTI]

    Wang, Ge

    Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using a more complete understanding of the relationship of lung structure and function. We combined a special to separate individual acini in the mouse lung. Interior scans of the parenchyma at a resolution of 2 µm

  17. Toward Robotic Needle Steering in Lung Biopsy: A Tendon-Actuated Approach

    E-Print Network [OSTI]

    Toward Robotic Needle Steering in Lung Biopsy: A Tendon-Actuated Approach Louis B. Kratchman is advantageous for transthoracic lung biopsies, which are typically performed with rigid, straight biopsy needles for transthoracic lung biopsy. The system is designed to insert and steer the needle under Computed Tomography (CT

  18. A novel strategy for surface modification of superparamagnetic iron oxide nanoparticles for lung cancer imaging

    E-Print Network [OSTI]

    Gao, Jinming

    A novel strategy for surface modification of superparamagnetic iron oxide nanoparticles for lung-step procedure for the surface functionalization of SPIO nanoparticles with a lung cancer-targeting peptide and demonstrate high T2 relaxivity. The nanoprobes are specific in targeting avb6­expressing lung cancer cells

  19. Experimental Evaluation of a Model for Oxygen Exchange in a Pulsating Intravascular Artificial Lung

    E-Print Network [OSTI]

    Federspiel, William J.

    Experimental Evaluation of a Model for Oxygen Exchange in a Pulsating Intravascular Artificial Lung an intravascular hollow fiber artificial lung that uses a pulsating balloon located within the fiber bundle in pulsating intravascular artificial lungs. In this study we evaluate the O2 exchange model with gas exchange

  20. Using Continuum Robots to Enable Transoral Access to the Peripheral Lung for Minimally Invasive Biopsy

    E-Print Network [OSTI]

    Using Continuum Robots to Enable Transoral Access to the Peripheral Lung for Minimally Invasive Biopsy Arthur W. Mahoney, Philip J. Swaney, and Robert J. Webster III Lung cancer kills more people than reach regions adjacent to bronchii. Enables access to the peripheral lung for biopsy without puncturing

  1. Influence of Pulmonary Surfactant Protein B on Model Lung Surfactant Monolayers

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Influence of Pulmonary Surfactant Protein B on Model Lung Surfactant Monolayers Frank Bringezu reveal that human lung surfactant protein SP-B1-78 and the dimer of the amino terminus dSP-B1-25 modify be essential for proper peptide function. Introduction Lung surfactant is a complex mixture of lipids

  2. Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia

    E-Print Network [OSTI]

    Chesler, Naomi C.

    Collagen-related gene and protein expression changes in the lung in response to chronic hypoxia changes in gene and protein expression in the lungs of mice exposed to hypoxia for 0, 3, 6, 10 and 15 days was increased in whole lungs as early as 6 days of hypoxia and increased monotonically with longer exposures

  3. Comment on ``Ultrasound-induced lung hemorrhage is not caused by inertial cavitation''

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Comment on ``Ultrasound-induced lung hemorrhage is not caused by inertial cavitation'' [J. Acoust­1297 2000 that ultrasound-induced lung hemorrhage is not caused by inertial cavitation. An argument is provided that illustrates how cavitation inception conditions in the lungs of animals are not altered

  4. AN INTEGRATED LUNG-ON-A-CHIP MICROFLUIDIC PLATFORM WITH REAL-TIME BIOCHEMICAL SENSING

    E-Print Network [OSTI]

    Kassegne, Samuel Kinde

    AN INTEGRATED LUNG-ON-A-CHIP MICROFLUIDIC PLATFORM WITH REAL-TIME BIOCHEMICAL SENSING, without finding it. ­ Lucius Annaeus Seneca #12;v ABSTRACT OF THE THESIS An Integrated Lung for detection. In this research, we replicate the Lung-on- a-Chip platform with a cystic fibrosis cell line

  5. THRESHOLD ESTIMATES OF ULTRASOUND-INDUCED LUNG HEMORRHAGE IN ADULT RATS: ROLE OF PULSE DURATION

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    THRESHOLD ESTIMATES OF ULTRASOUND-INDUCED LUNG HEMORRHAGE IN ADULT RATS: ROLE OF PULSE DURATION W-induced lung hemorrhage has been estimated as a function of pulse duration (PD) in adult rats. A total of 220, there were five in situ (at the lung surface) peak rarefactional pressures. For PDs of 1.3, 4.4, 8.2, and 11

  6. Effect of pulse polarity and energy on ultrasound-induced lung hemorrhage in adult rats

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Effect of pulse polarity and energy on ultrasound-induced lung hemorrhage in adult rats Leon A the role of inertial cavitation in ultrasound-induced lung hemorrhage by examining the effect of pulse polarity at a common in situ at the lung surface peak rarefactional pressure pr(in situ) and at a common

  7. Attenuation and speed of ultrasoundin lung BioacousticResearchLaboratory,Universityof Illinois,Urbana,Illinois61801

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Attenuation and speed of ultrasoundin lung F. Dunn Bioacoustic in freshly excised dog lung at 1 MHz was un- usuallyhigh,viz., morethananorderofmagnitude greater than air excised lung was ligated at the bronchial tube to retain such residual air that the density of the speci

  8. Lesion Resolution Following Exposure of Rat Lung to Pulsed Ultrasound James F. Zachary,1

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Lesion Resolution Following Exposure of Rat Lung to Pulsed Ultrasound James F. Zachary,1 Leon A ultrasound-induced lung hemorrhage in mice, rats, rabbits, monkeys, and pigs. This study characterized the temporal reparative (healing) responses in lung fol- lowing the induction of lesions by pulsed ultrasound

  9. Reduced Order Constrained Optimization (ROCO):1 Clinical Application to Lung IMRT2

    E-Print Network [OSTI]

    Reduced Order Constrained Optimization (ROCO):1 Clinical Application to Lung IMRT2 Hans Stabenau,1 quickly and automatically for advanced lung cancer patients. Our new ROCO imple- mentation works constrained optimization computationally efficient. Results: We apply ROCO to 12 stage III non-small-cell lung

  10. Feasibility of Locating Tumours in Lung via Kinesthetic Feedback Greig L. McCreery

    E-Print Network [OSTI]

    Naish, Michael D.

    Feasibility of Locating Tumours in Lung via Kinesthetic Feedback Greig L. McCreery Ana Luisa Trejos Michael D. Naish Rajni V. Patel Richard A. Malthaner Abstract Background Localizing lung tumours during-operative imaging cannot map directly to the intra-operative lung. This study analyzes the force sensing performance

  11. Medical Physics Letter Digital tomosynthesis of the chest for lung nodule detection: Interim

    E-Print Network [OSTI]

    Medical Physics Letter Digital tomosynthesis of the chest for lung nodule detection: Interim tomosynthesis for improving detectability of small lung nodules. Twenty-one patients under- going computed tomography CT to follow up lung nodules were consented and enrolled to receive an additional digital PA chest

  12. Tendons, Concentric Tubes, and a Bevel Tip: Three Steerable Robots in One Transoral Lung Access System

    E-Print Network [OSTI]

    Tendons, Concentric Tubes, and a Bevel Tip: Three Steerable Robots in One Transoral Lung Access, and Robert J. Webster III1, Senior Member, IEEE Abstract-- Lung cancer is the most deadly form of cancer between-the-ribs needle insertion because it is less invasive and reduces risk of lung collapse. Yet many

  13. Feasibility Study of Dual Energy Radiographic Imaging for Target Localization in Radiotherapy for Lung Tumors

    E-Print Network [OSTI]

    for Lung Tumors Jie Huo1 , Xianfeng Zhu1 , Yang Dong2 , Zhiyong Yuan2 , Ping Wang2 *, Xuemin Wang1 , Gang. 10 lung cancer patients who underwent radiotherapy each with gold markers implanted in the tumor were Imaging for Target Localization in Radiotherapy for Lung Tumors. PLoS ONE 9(9): e108823. doi:10

  14. A Comparative In Vitro Hemolysis Study of a Pulsating Intravenous Artificial Lung

    E-Print Network [OSTI]

    Federspiel, William J.

    A Comparative In Vitro Hemolysis Study of a Pulsating Intravenous Artificial Lung LAURA W. LUND oxygenation and carbon dioxide removal lead to further damage of the ailing lungs.1 An estimated 150) as a method for providing temporary respiratory support and allowing the lungs of ARDS patients to heal.4

  15. An Adaptive, Knowledge-Driven Medical Image Search Engine for Interactive Diffuse Parenchymal Lung Disease

    E-Print Network [OSTI]

    Chandy, John A.

    An Adaptive, Knowledge-Driven Medical Image Search Engine for Interactive Diffuse Parenchymal Lung Abstract Characterization and quantification of the severity of diffuse parenchymal lung diseases (DPLD have been obtained on a small test set. Keywords: CT; texture analysis; interstitial lung disease

  16. Ultrasound-induced lung hemorrhage is not caused by inertial cavitation

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Ultrasound-induced lung hemorrhage is not caused by inertial cavitation William D. O'Brien, Jr, the pathogenesis of lung hemorrhage due to exposure to clinical diagnostic levels of ultrasound has been attributed that directly contradict the hypothesis that ultrasound-induced lung hemorrhage is caused by inertial cavitation

  17. Motion Planning for a Three-Stage Multilumen Transoral Lung Access System

    E-Print Network [OSTI]

    Alterovitz, Ron

    Motion Planning for a Three-Stage Multilumen Transoral Lung Access System Alan Kuntz, Luis G. Torres, Richard H. Feins, Robert J. Webster III, and Ron Alterovitz Abstract-- Lung cancer is the leading required for a definitive diagnosis, but current low-risk clinical options for lung biopsy cannot access

  18. LETTER doi:10.1038/nature13173 Reconstructing lineage hierarchies of the distal lung

    E-Print Network [OSTI]

    Quake, Stephen R.

    LETTER doi:10.1038/nature13173 Reconstructing lineage hierarchies of the distal lung epithelium The mammalian lung is a highly branched network in which the distal regions of the bronchial tree transform-mapping, the mechanisms that control the progression of lung progenitors along distinct lineages into mature alveolar cell

  19. Video Article Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung

    E-Print Network [OSTI]

    Chesler, Naomi C.

    Video Article Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused://www.jove.com/details.php?id=2690 DOI: 10.3791/2690 Keywords: Medicine, Issue 50, ex-vivo, mouse, lung, pulmonary vascular impedance of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow. J. Vis. Exp. (50), e2690

  20. Silicon Photonic Crystal Microcavity Biosensors for Label Free Highly Sensitive and Specific Lung Cancer Detection

    E-Print Network [OSTI]

    Chen, Ray

    Silicon Photonic Crystal Microcavity Biosensors for Label Free Highly Sensitive and Specific Lung detect lung cancer cell lysates with high sensitivity down to 2 cells per microliter with silicon based detection of control experiment to verify specificity again. Primary lung cancer develops from epithelial

  1. Robust Segmentation of Challenging Lungs in CT using Multi-Stage Learning

    E-Print Network [OSTI]

    Robust Segmentation of Challenging Lungs in CT using Multi-Stage Learning and Level Set.Kevin Zhou1 Abstract Automatic segmentation of lung tissue in thoracic CT scans is useful for diagnosis and treatment planning of pulmonary diseases. Unlike healthy lung tissue that is easily identifiable in CT scans

  2. Relating maximum airway dilation and subsequent reconstriction to reactivity in human lungs

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Relating maximum airway dilation and subsequent reconstriction to reactivity in human lungs Lauren in human lungs. J Appl Physiol 96: 1808­1814, 2004. First published February 6, 2004; 10.1152/japplphysiol reactivity in healthy lungs by prohibiting DI for an extended period. The present study had two goals. First

  3. Technical Reports Ultra-low Dose Lung CT Perfusion Regularized by

    E-Print Network [OSTI]

    Wang, Ge

    Technical Reports Ultra-low Dose Lung CT Perfusion Regularized by a Previous Scan1 Hengyong Yu, Ph­regularized reconstruction (PSRR) method was proposed to reduce radiation dose and applied to lung perfusion studies. Normal and ultra-low-dose lung computed tomographic perfusion studies were compared in terms of the estimation

  4. Tissue heterogeneity in the mouse lung: effects of elastase treatment Satoru Ito,1

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Tissue heterogeneity in the mouse lung: effects of elastase treatment Satoru Ito,1 Edward P heterogeneity in the mouse lung: effects of elastase treatment. J Appl Physiol 97: 204­212, 2004. First to characterize heterogeneity of tissue elasticity of the lung. The model includes a parallel set of pathways

  5. Multi-stage Learning for Robust Lung Segmentation in Challenging CT Volumes

    E-Print Network [OSTI]

    Multi-stage Learning for Robust Lung Segmentation in Challenging CT Volumes Michal Sofka1 , Jens Imaging, Siemens Healthcare, Oxford, UK Abstract. Simple algorithms for segmenting healthy lung parenchyma an ini- tialization of a statistical shape model of the lungs. The initialization first detects

  6. Location registration and recognition (LRR) for serial analysis of nodules in lung CT scans

    E-Print Network [OSTI]

    Location registration and recognition (LRR) for serial analysis of nodules in lung CT scans Michal t In the clinical workflow for lung cancer management, the comparison of nodules between CT scans from subsequent in investigating the condition of the lung. The algorithm uses a combination of feature extraction, indexing

  7. JAP-00590-2004 Mechanics, nonlinearity, and failure strength of lung tissue in a mouse

    E-Print Network [OSTI]

    Lutchen, Kenneth

    JAP-00590-2004 Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model% higher in the PPE-treated group (P lung hydroxyproline content, which represents remodeling may play a significant role in all aspects of lung functional changes leading to progressive

  8. Environmental Tobacco Smoke Effects on the Primary Lipids of Lung Surfactant

    E-Print Network [OSTI]

    Zasadzinski, Joseph A.

    Environmental Tobacco Smoke Effects on the Primary Lipids of Lung Surfactant Frank Bringezu,, Kent. In Final Form: December 2, 2002 The effects of environmental tobacco smoke (ETS) on lung surfactant are difficult to determine from analysis of human and animal lung lavage due to large variations in surfactant

  9. Relation Between Structure, Function, and Imaging in a Three-Dimensional Model of the Lung

    E-Print Network [OSTI]

    Lutchen, Kenneth

    Relation Between Structure, Function, and Imaging in a Three-Dimensional Model of the Lung NORA T morphometric mod- els to predict function relations in the lung. These models, however, are not anatomically explicit. We have advanced a three-dimensional airway tree model to relate dynamic lung function

  10. Response to ``Comment on `Ultrasound-induced lung hemorrhage is not caused by inertial cavitation'''

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    Response to ``Comment on `Ultrasound-induced lung hemorrhage is not caused by inertial cavitation cavitation nuclei in lung versus other tissues such that overpressure does not affect the inertial cavitation threshold in lung, then there would be an impact on the con- clusion in our publication.2 To examine

  11. Antinuclear Antibodies as Potential Markers of Lung Cancer1 Felix Fernandez-Madrid,2

    E-Print Network [OSTI]

    VandeVord, Pamela

    Antinuclear Antibodies as Potential Markers of Lung Cancer1 Fe´lix Ferna´ndez-Madrid,2 Pamela J of ANAs in lung cancer. We have previously reported that autoantibodies to collagen antigens resembling those found in the connective tissue diseases are consistently detected in the sera from lung cancer

  12. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review)

    E-Print Network [OSTI]

    Rau, Don C.

    Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth://www.thecochranelibrary.com Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review.09. Comparison 01 Corticosteroids versus placebo or no treatment, Outcome 09 Chronic lung disease . 83 Analysis

  13. Lung Sound Recognition Using Model-Theory Based Feature Selection and Fusion

    E-Print Network [OSTI]

    Kokar, Mieczyslaw M.

    Lung Sound Recognition Using Model-Theory Based Feature Selection and Fusion Zbigniew Korona recognition methodology to the recognition of lung sounds. Two main features of this method- ology are features using an entropy-based criterion. To evaluate the methodology we used both normal lung sounds

  14. Multi-level Ground Glass Nodule Detection and Segmentation in CT Lung Images

    E-Print Network [OSTI]

    Corso, Jason J.

    Multi-level Ground Glass Nodule Detection and Segmentation in CT Lung Images Yimo Tao1,2 , Le Lu1. Early detection of Ground Glass Nodule (GGN) in lung Computed Tomography (CT) images is important for lung cancer prog- nosis. Due to its indistinct boundaries, manual detection and segmenta- tion of GGN

  15. MONITORING LUNG DISEASE USING ELECTRONIC STETHOSCOPE ARRAYS Kyle Mulligan, Andy Adler, and Rafik Goubran

    E-Print Network [OSTI]

    Adler, Andy

    MONITORING LUNG DISEASE USING ELECTRONIC STETHOSCOPE ARRAYS Kyle Mulligan, Andy Adler, and Rafik evidence has shown that lung protective ventilation strategies lead to dramatic improvements in patient health by reducing ventilator induced lung injury (VILI) 1 . To protect against VILI, many novel modes

  16. Ultra-Fast Absorption of Amorphous Pure Drug Aerosols Via Deep Lung Inhalation

    E-Print Network [OSTI]

    Rabinowitz, Joshua D.

    Ultra-Fast Absorption of Amorphous Pure Drug Aerosols Via Deep Lung Inhalation JOSHUA D. RABINOWITZ. A promising means of accelerating drug action is through rapid systemic drug administration via deep lung inhalation. The speed of pulmonary drug absorption depends on the site of aerosol deposition within the lung

  17. Lung sound localization using array of acoustic S.M. Akramus Salehin and Thushara D. Abhayapala

    E-Print Network [OSTI]

    Abhayapala, Thushara D.

    1 Lung sound localization using array of acoustic sensors S.M. Akramus Salehin and Thushara D University Abstract-- This paper presents a localization algorithm to detect lung sounds using an circular by computer simulations. I. INTRODUCTION Lung disorders or injury can result in changes in the spectral and

  18. Selenium and Lung Cancer: A Quantitative Analysis of Heterogeneity in the Current

    E-Print Network [OSTI]

    California at Berkeley, University of

    Selenium and Lung Cancer: A Quantitative Analysis of Heterogeneity in the Current Epidemiological on sele- nium and lung cancer and identify sources of heterogeneity among studies. When all studies were.30). Overall, these results suggest that selenium may have some protective effect against lung cancer

  19. Mechanism Design and Implementation for Lung Exchange Suiqian Luo and Pingzhong Tang

    E-Print Network [OSTI]

    Tang, Pingzhong

    Mechanism Design and Implementation for Lung Exchange Suiqian Luo and Pingzhong Tang Institute@tsinghua.edu.cn Abstract We explore the mechanism design problem for lung exchange and its implementation in practice. We prove that determining whether there exists a non- trivial solution of the lung exchange problem is NP

  20. Genome-wide association study of lung function phenotypes in a founder population

    E-Print Network [OSTI]

    Abney, Mark

    Genome-wide association study of lung function phenotypes in a founder population Tsung-Chieh Yao, Detroit, Mich, Baltimore, Md, Madison, Wis, and Taoyuan, Taiwan Background: Lung function is a long) associated with lung function. Methods: We performed a genome-wide association study (GWAS) of FEV1, forced

  1. Choice of reconstructed tissue properties affects interpretation of lung EIT images

    E-Print Network [OSTI]

    Adler, Andy

    Choice of reconstructed tissue properties affects interpretation of lung EIT images Bartlomiej patients. In lung EIT, the EIT inverse problem is commonly linearised and only changes in electrical properties of the lung and artefacts introduced by the linearisation. #12;Choice of reconstructed tissue

  2. The Heparan Sulfate Proteoglycan GPC3 Is a Potential Lung Tumor Suppressor

    E-Print Network [OSTI]

    Tian, Weidong

    The Heparan Sulfate Proteoglycan GPC3 Is a Potential Lung Tumor Suppressor Han Kim,* Guo-Liang Xu University School of Medicine, Boston, Massachusetts Recently, we used gene expression profiling of lung pathways associated with ciga- rette smoking and lung carcinogenesis. The gene encoding Glypican 3

  3. Stroke Belt Initiative 1National Heart, Lung, and Blood Institute Stroke Belt Initiative

    E-Print Network [OSTI]

    Shen, Jun

    Stroke Belt Initiative 1National Heart, Lung, and Blood Institute Stroke Belt Initiative NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Project Accomplishments and Lessons Learned Overview Cerebrovascular to those living in other regions of the country. The National Heart, Lung, and Blood Institute (NHLBI

  4. Lung deflation and oxygen pulse in COPD: Results from the NETT randomized trial*

    E-Print Network [OSTI]

    Lung deflation and oxygen pulse in COPD: Results from the NETT randomized trial* Carolyn E. Come a July 2011 Available online 16 August 2011 KEYWORDS Cardiac function; Hyperinflation; Lung volume function. We examined whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume

  5. Original Contribution Elevated Lung Cancer in Younger Adults and Low Concentrations of Arsenic

    E-Print Network [OSTI]

    California at Berkeley, University of

    Original Contribution Elevated Lung Cancer in Younger Adults and Low Concentrations of Arsenic-term effects of arsenic. We performed a case-control study of lung cancer from 2007 to 2010 in areas or more years ago resulted in odds ratios for lung cancer of 1.00, 1.43 (90% confidence interval: 0.82, 2

  6. MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells

    E-Print Network [OSTI]

    Gao, Jinming

    MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells Jagadeesh Setti micelle (MFM) system that is encoded with a lung cancer-targeting peptide (LCP), and encapsulated. The LCP-encoded MFM showed significantly increased Rv 6-dependent cell targeting in H2009 lung cancer

  7. Clinical Investigation: Breast Cancer Predicting the Risk of Secondary Lung Malignancies

    E-Print Network [OSTI]

    Brenner, David Jonathan

    Clinical Investigation: Breast Cancer Predicting the Risk of Secondary Lung Malignancies Associated. Accepted for publication Sep 19, 2011 Summary The risk of secondary lung cancers after whole breast lower risk of secondary lung malignancy than treatment with the supine breast tech- nique. Breast

  8. Learning Methods for Lung Tumor Markerless Gating in Image-Guided Radiotherapy

    E-Print Network [OSTI]

    Dy, Jennifer G.

    Learning Methods for Lung Tumor Markerless Gating in Image-Guided Radiotherapy Ying Cui Dept. For gated lung cancer radiotherapy, it is difficult to generate ac- curate gating signals due to the large techniques, we apply them on five sequences of fluoroscopic images from five lung cancer patients against

  9. Identifying Mathematical Models of the Mechanically Ventilated Lung Using Equation Discovery

    E-Print Network [OSTI]

    Kersting, Kristian

    1 Identifying Mathematical Models of the Mechanically Ventilated Lung Using Equation Discovery in intensive care medicine by all means. Nevertheless, it can induce severe mechanical stress to the lung, which generally impairs the outcome of the therapy. To reduce the risk of a ventilator induced lung

  10. Circulation during intermittent lung ventilation in the ~artel" snake Thamnophis WARREN B URG(;RFS

    E-Print Network [OSTI]

    Burggren, Warren

    I .'11 Circulation during intermittent lung ventilation in the ~artel" snake Thamnophis WARREN B" Vi'lllW5 Received April 26, 1'177 RU\\lung "/-'r1t relationship, within the central arterial circulation ",'ere observed during intermittent. voluntary lung

  11. Data-driven classification of ventilated lung tissues using electrical impedance tomography

    E-Print Network [OSTI]

    Adler, Andy

    Data-driven classification of ventilated lung tissues using electrical impedance tomography Camille for identifying ventilated lung regions utilizing electrical impedance tomography (EIT) images rely on dividing of a data-driven classification method to identify ventilated lung ROI based on forming k clusters from

  12. INT J TUBERC LUNG DIS 15(8):9961004 2011 The Union

    E-Print Network [OSTI]

    Cohen, Ted

    INT J TUBERC LUNG DIS 15(8):996­1004 ©2011 The Union doi:10.5588/ijtld.11.0062 STATE OF THE ART University, Taipei, Taiwan; International Union Against Tuberculosis and Lung Disease, Paris, France series in the Journal. Int J Tuberc Lung Dis 2011; 15(1): 3. No 1: Lienhardt C, Cobelens F G J

  13. Arsenic methylation and lung and bladder cancer in a case-control study in northern Chile

    E-Print Network [OSTI]

    California at Berkeley, University of

    Arsenic methylation and lung and bladder cancer in a case-control study in northern Chile Dawit Accepted 20 November 2013 Available online 1 December 2013 Keywords: Arsenic Cancer Methylation Lung about its role in lung cancer, the most common cause of arsenic-related death, or about its impacts

  14. Lobe-based Estimating Ventilation and Perfusion from 3D CT scans of the Lungs

    E-Print Network [OSTI]

    Warren, Joe

    Lobe-based Estimating Ventilation and Perfusion from 3D CT scans of the Lungs Travis McPhail Joe Warren Rice University Thomas Guerrero, M.D. M.D. Anderson Cancer Center Introduction Lung cancer for lung cancer includes surgical removal or radiation therapy. 3D imaging technologies such CT, MRI

  15. Original Contribution Acute Myocardial Infarction Mortality in Comparison with Lung and Bladder

    E-Print Network [OSTI]

    California at Berkeley, University of

    Original Contribution Acute Myocardial Infarction Mortality in Comparison with Lung and Bladder, 2007; accepted for publication July 27, 2007. Arsenic in drinking water is known to be a cause of lung lung and bladder cancer, AMI mortality was the predominant cause of excess

  16. IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas Autoinducer

    E-Print Network [OSTI]

    Springer, Timothy A.

    IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas is caused, in part, by the produc- tion of the chemokine IL-8, which recruits neutrophils into the lung. These findings support the concept that the severe lung damage that accompanies P. aeruginosa infections

  17. FALSE POSITIVE REDUCTION IN LUNG GGO NODULE DETECTION WITH 3D VOLUME SHAPE DESCRIPTOR

    E-Print Network [OSTI]

    Wu, Ying

    FALSE POSITIVE REDUCTION IN LUNG GGO NODULE DETECTION WITH 3D VOLUME SHAPE DESCRIPTOR Ming Yang. Malvern, PA 19355 Evanston, IL 60208 ABSTRACT Lung nodule detection, especially ground glass opacity (GGO on a difficult mixture lung nodule dataset with average 81% detec- tion rate and 4.3 false positives per volume

  18. Telomere length in circulating leukocytes is associated with lung function and

    E-Print Network [OSTI]

    Nyholt, Dale R.

    Telomere length in circulating leukocytes is associated with lung function and disease Eva Albrecht intrinsic age-related processes contribute to the interindividual variability of lung function. Our meta-analysis of 14 studies included 934 COPD cases with 15846 controls defined according to the Global Lungs

  19. Research Article Increased Lung and Bladder Cancer Incidence in Adults after

    E-Print Network [OSTI]

    California at Berkeley, University of

    Research Article Increased Lung and Bladder Cancer Incidence in Adults after In Utero and Early resulted in increased mortality in adults from several outcomes, including lung and bladder cancer. Methods data. Subjects included 221 lung and 160 bladder cancer cases diagnosed in northern Chile from 2007

  20. A NOVEL FRAMEWORK FOR ACCURATE LUNG SEGMENTATION USING GRAPH CUTS Asem M. Ali1

    E-Print Network [OSTI]

    Louisville, University of

    A NOVEL FRAMEWORK FOR ACCURATE LUNG SEGMENTATION USING GRAPH CUTS Asem M. Ali1 Ayman S. El-Baz 2 Bioengineering Department, University of Louisville ABSTRACT The closeness of the gray levels between lung tissues and the chest tissues makes lung segmentation based only on image signals dif- ficult. This work

  1. Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

    E-Print Network [OSTI]

    Sander, Maike

    Sox9 plays multiple roles in the lung epithelium during branching morphogenesis Briana E. Rockicha, Durham, NC, and approved October 2, 2013 (received for review June 21, 2013) Lung branching morphogenesis lung. Intricate regulation of signaling pathways, tran- scription factors, and epithelial

  2. KILLING OF TARGET CELLS DUE TO RADON PROGENY IN THE HUMAN LUNG

    E-Print Network [OSTI]

    Yu, Peter K.N.

    KILLING OF TARGET CELLS DUE TO RADON PROGENY IN THE HUMAN LUNG B. M. F. Lau1 , D. Nikezic1,2 and K to inhaled radon progeny in the human lung. The present work uses the microdosimetric approach and determines/alleviate this discrepancy, including those based on different lung morpho- metry models(4) , different ethnic groups(5

  3. Appeared in: IEEE Visualization 2003 Hybrid Segmentation and Exploration of the Human Lungs

    E-Print Network [OSTI]

    Bartz, Dirk

    Appeared in: IEEE Visualization 2003 Hybrid Segmentation and Exploration of the Human Lungs Dirk on a PC with a P3 @ 850 MHz. Abstract Segmentation of the tracheo-bronchial tree of the lungs is notori, the complementary vascular tree of the lungs can be segmented. Furthermore, we modified our virtual endoscopy system

  4. The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly

    E-Print Network [OSTI]

    Mecham, Robert

    The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly Adrian Shifren and Robert P properties of the lung are largely determined by the connective tissue networks laid down during development. The macromolecules most important for lung mechanics and structural integrity are collagen, elastin

  5. A mechanochemical model for auto-regulation of lung airway surface layer volume

    E-Print Network [OSTI]

    Welch, Greg

    A mechanochemical model for auto-regulation of lung airway surface layer volume Gregory Herschlag a liquid in the lung. c Sources of stress (from cilia and breathe) and channel inhibitors are included. c in the lung airway surface layer (ASL) by coupling biochemical kinetics, transient ASL volume, and homeostatic

  6. Evaluation of Reconstructed Images of Regional Lung Changes Using a Model

    E-Print Network [OSTI]

    Adler, Andy

    Evaluation of Reconstructed Images of Regional Lung Changes Using a Model Robert P, Patterson1 A and Patterson 2004, Yang and Patterson 2010). In order to answer questions about regional lung changes, two regions were created in the posterior portion of the right lung where the resistivity can be independently

  7. Increased lung cancer risks are similar whether arsenic is ingested ALLAN H. SMITHa

    E-Print Network [OSTI]

    California at Berkeley, University of

    Increased lung cancer risks are similar whether arsenic is ingested or inhaled ALLAN H. SMITHa that inorganic arsenic was a human lung carcinogen based on studies involving exposure through inhalation. In 2004, IARC listed arsenic in drinking water as a cause of lung cancer, making arsenic the first

  8. ARTICLE doi:10.1038/nature12930 Alveolar progenitorand stem cells in lung

    E-Print Network [OSTI]

    Krasnow, Mark A.

    ARTICLE doi:10.1038/nature12930 Alveolar progenitorand stem cells in lung development, renewal or maintain AT1 and AT2 cells, and alveoli are a major site of lung cancer, the leading cause of cancer death2cellsisobservedfollowingbulklabellingofAT2cellpopulations8,9 . To circumvent slow turnover, lung injury models have been used and provide

  9. ORIGINAL ARTICLE Lung function in adults following in utero and childhood exposure

    E-Print Network [OSTI]

    California at Berkeley, University of

    ORIGINAL ARTICLE Lung function in adults following in utero and childhood exposure to arsenic water causes non-malignant lung disease, but nearly all data concern exposed adults. The desert city and long-term lung function. We present these preliminary findings because of the magnitude of the effects

  10. Neural Network Classifiers and Gene Selection Methods for Microarray Data on Human Lung Adenocarcinoma

    E-Print Network [OSTI]

    Narasimhan, Giri

    Neural Network Classifiers and Gene Selection Methods for Microarray Data on Human Lung with lung cancer gene expression data sets available from the CAMDA website. Many different classification several new methods for classifying gene expression data from lung cancer patients. Our approach uses

  11. GREIT: a unified approach to 2D linear EIT reconstruction of lung images

    E-Print Network [OSTI]

    Adler, Andy

    GREIT: a unified approach to 2D linear EIT reconstruction of lung images Andy Adler1 , John H the distribution of ventilation. However, most clinical and physiological research in lung EIT is done using older algorithm for lung EIT, called GREIT (Graz consensus Reconstruction algorithm for EIT). This paper describes

  12. SUPPLEMENTARY METHODS AND TABLES Drug transport from the blood into the lung tissue

    E-Print Network [OSTI]

    Kirschner, Denise

    1 SUPPLEMENTARY METHODS AND TABLES Drug transport from the blood into the lung tissue To study that enters the grid representing lung parenchyma via vascular sources, and diffuses among micro Once TNF inhibitors penetrate from blood into the lung tissue, they can bind TNF and thus block TNF

  13. LEVEL SET BASED RECONSTRUCTION ALGORITHM FOR EIT LUNG IMAGES Peyman Rahmati1

    E-Print Network [OSTI]

    Adler, Andy

    LEVEL SET BASED RECONSTRUCTION ALGORITHM FOR EIT LUNG IMAGES Peyman Rahmati1 , Manuchehr Soleimani2 the monitoring process. We represent lung images by applying the LSRM using difference solver and then compare in producing high quality, high contrast images of lung. Index Terms-- Inverse Problem, Electrical Impedence

  14. Biosynthesis and SupramolecularAssemblyof ProcollagenIV in Neonatal Lung

    E-Print Network [OSTI]

    Blumberg, Bruce

    Biosynthesis and SupramolecularAssemblyof ProcollagenIV in Neonatal Lung Bruce Blumberg, and the concentration of specific RNAs coding for pro- collagen IV were measured in neonatal rat lungs. Both decreased IV was followed in neonatal rat, mouse, and chick lungs, which actively elaborate endothelial

  15. Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies

    E-Print Network [OSTI]

    Domany, Eytan

    Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies Introduction Bronchiolitis obliterans syndrome (BOS) in lung trans- plant recipients is defined by progressive-term survival in lung transplant recipients2,3 and develops in nearly all patients to varying degrees.4

  16. ROBUST SEGMENTATION OF LUNG TISSUE IN CHEST CT SCANNING Amal Farag, James Graham and Aly Farag

    E-Print Network [OSTI]

    Louisville, University of

    ROBUST SEGMENTATION OF LUNG TISSUE IN CHEST CT SCANNING Amal Farag, James Graham and Aly Farag.edu ABSTRACT This paper deals with segmentation of the lung tissues from low dose CT (LDCT) scans of the chest. Goal is correct segmentation as well as maintaining the details of the lung region in the chest cavity

  17. Unsupervised localization of heart and lung regions in EIT images: a validation study

    E-Print Network [OSTI]

    Adler, Andy

    Unsupervised localization of heart and lung regions in EIT images: a validation study Damien an algorithm for automatic detection of heart and lung regions in a time series of EIT images. Candidate, it is important to accurately identify the relevant anatomical regions: the heart and lungs (H&L). Several methods

  18. Design and Analysis of a Wireless Nanosensor Network for Monitoring Human Lung Cells

    E-Print Network [OSTI]

    New South Wales, University of

    Design and Analysis of a Wireless Nanosensor Network for Monitoring Human Lung Cells Eisa Zarepour one day. In this paper, we design and analyse a WNSN for monitoring human lung cells. We find that influences the terahertz channel inside lung cells. The channel is characterised as a two-state channel

  19. A Framework for Automatic Segmentation of Lung Nodules from Low Dose Chest CT Scans

    E-Print Network [OSTI]

    Louisville, University of

    A Framework for Automatic Segmentation of Lung Nodules from Low Dose Chest CT Scans Ayman El-Baz1 the high accuracy of the proposed approach. 1 Introduction Because lung cancer is the most common cause 1, an initial LDCT slice is segmented with our algorithms introduced in [3] to isolate lung tissues

  20. Decrements in Lung Function Related to Arsenic in Drinking Water in West Bengal, India

    E-Print Network [OSTI]

    California at Berkeley, University of

    Decrements in Lung Function Related to Arsenic in Drinking Water in West Bengal, India Ondine S­2000, the authors investigated relations between lung function, respiratory symptoms, and arsenic in drinking water, consumption of arsenic-contaminated water was associated with respiratory symptoms and reduced lung function

  1. Automatic Lung Segmentation of Volumetric Low-Dose CT Scans Using Graph Cuts

    E-Print Network [OSTI]

    Louisville, University of

    Automatic Lung Segmentation of Volumetric Low-Dose CT Scans Using Graph Cuts Asem M. Ali and Aly A for unsupervised segmentation of the lung region from low dose computed tomography (LDCT) images. We follow distribution model. To better spec- ify region borders between lung and chest, each empirical distribution

  2. Effects of disabled vehicles stopped on a freeway shoulder 

    E-Print Network [OSTI]

    Wilshire, Roy Leon

    1963-01-01

    EFFECTS OF !3ISABLED VEHICLES STOPPFD ON A FREEWAY SHOULDER A Thesis ROY LEON WILSHIRE S" bmitted to tl-, e Graduate School of the Agricultural and Mechar. ical Col lege of Texas in partial fulfillment of the t equiremcnts for the degree... of MASTER OF SCIENCE August 1963 Major Subject; Cevil Engineering EFFECTS OF DISABLED VEHICLES STOPPED ON A FREEWAY SHOULDER A Thesis By ROY LEON WILSHIRE Approved as to style and content by: Chairman of Committee H ad of Department August 196 3...

  3. Morphology of PolyethyleneCarbon Black Composites G. BEAUCAGE,1

    E-Print Network [OSTI]

    Beaucage, Gregory

    -ray scattering (SAXS) study of a conductive grade of carbon black and carbon black­polymer composites and a power-law scaling of polydispersity. One use of conductive black­polyethylene composites is in circuit(methyl methacrylate); carbon black; filler; composite; conductivity; percolation INTRODUCTION The morphology

  4. Report on the WORKSHOP ON COMMERCIALIZATION OF BLACK LIQUOR

    E-Print Network [OSTI]

    .3. Gasifier Supplier Perspectives 11 Black Liquor Gasifier Suppliers 12 Biomass Gasifier Suppliers 13 5

  5. Testing black hole candidates with electromagnetic radiation

    E-Print Network [OSTI]

    Bambi, Cosimo

    2015-01-01

    Astrophysical black hole candidates are thought to be the Kerr black holes of general relativity, but there is currently no direct observational evidence that the spacetime geometry around these objects is described by the Kerr solution. The study of the properties of the electromagnetic radiation emitted by gas or stars orbiting these objects can potentially test the Kerr black hole hypothesis. In this paper, I review the state of the art of this research field, describing the possible approaches to test the Kerr metric with current and future observational facilities and discussing current constraints.

  6. Quasinormal Modes of Dirty Black Holes

    E-Print Network [OSTI]

    P. T. Leung; Y. T. Liu; W. -M. Suen; C. Y. Tam; K. Young

    1999-03-08

    Quasinormal mode (QNM) gravitational radiation from black holes is expected to be observed in a few years. A perturbative formula is derived for the shifts in both the real and the imaginary part of the QNM frequencies away from those of an idealized isolated black hole. The formulation provides a tool for understanding how the astrophysical environment surrounding a black hole, e.g., a massive accretion disk, affects the QNM spectrum of gravitational waves. We show, in a simple model, that the perturbed QNM spectrum can have interesting features.

  7. Black Hole Thermodynamics and Statistical Mechanics

    E-Print Network [OSTI]

    Steven Carlip

    2008-07-28

    We have known for more than thirty years that black holes behave as thermodynamic systems, radiating as black bodies with characteristic temperatures and entropies. This behavior is not only interesting in its own right; it could also, through a statistical mechanical description, cast light on some of the deep problems of quantizing gravity. In these lectures, I review what we currently know about black hole thermodynamics and statistical mechanics, suggest a rather speculative "universal" characterization of the underlying states, and describe some key open questions.

  8. Some remarks on black hole thermodynamics

    E-Print Network [OSTI]

    R. Y. Chiao

    2011-02-04

    Two thermodynamic "paradoxes" of black hole physics are re-examined. The first is that there is a thermal instability involving two coupled blackbody cavities containing two black holes, and second is that a classical black hole can swallow up entropy in the form of ambient blackbody photons without increasing its mass. The resolution of the second paradox by Bekenstein and by Hawking is re-visited. The link between Hawking radiation and Wigner's superluminal tunneling time is discussed using two equivalent Feynman diagrams, and Feynman's re-interpretation principle.

  9. Thermodynamics of Dyonic Lifshitz Black Holes

    E-Print Network [OSTI]

    Tobias Zingg

    2011-07-15

    Black holes with asymptotic anisotropic scaling are conjectured to be gravity duals of condensed matter system close to quantum critical points with non-trivial dynamical exponent z at finite temperature. A holographic renormalization procedure is presented that allows thermodynamic potentials to be defined for objects with both electric and magnetic charge in such a way that standard thermodynamic relations hold. Black holes in asymptotic Lifshitz spacetimes can exhibit paramagnetic behavior at low temperature limit for certain values of the critical exponent z, whereas the behavior of AdS black holes is always diamagnetic.

  10. Testing the Kerr black hole hypothesis

    E-Print Network [OSTI]

    Cosimo Bambi

    2011-10-13

    It is thought that the final product of the gravitational collapse is a Kerr black hole and astronomers have discovered several good astrophysical candidates. While there is some indirect evidence suggesting that the latter have an event horizon, and therefore that they are black holes, a proof that the space-time around these objects is described by the Kerr geometry is still lacking. Recently, there has been an increasing interest in the possibility of testing the Kerr black hole hypothesis with present and future experiments. In this paper, I briefly review the state of the art of the field, focussing on some recent results and work in progress.

  11. Scalar Perturbations of Charged Dilaton Black Holes

    E-Print Network [OSTI]

    Sharmanthie Fernando; Keith Arnold

    2015-08-01

    We have studied the scalar perturbation of static charged dilaton black holes in 3+1 dimensions. The black hole considered here is a solution to the low-energy string theory in 3+1 dimensions. The quasinormal modes for the scalar perturbations are calculated using the third order WKB method. The dilaton coupling constant has a considerable effect on the values of quasi normal modes. It is also observed that there is a linear relation between the quasi normal modes and the temperature for large black holes.

  12. Energy density bounds for black strings

    E-Print Network [OSTI]

    Shinya Tomizawa

    2005-06-07

    The conserved charge called Y-ADM mass density associated with asymptotically translational Killing-Yano tensor gives us an appropriate physical meaning about the energy density of $p$ brane spacetimes or black strings. We investigated the positivity of energy density in black string spacetimes, using the spinorial technique introduced by Witten. Recently, the positivity of Y-ADM mass density in p brane spacetimes was discussed. In this paper, we will extend this discussion to the transversely asymptotically flat black string spacetimes containing an apparent horizon. We will give the sufficient conditions for the Y-ADM mass density to become positive in such spacetimes.

  13. Learning Disability Liaison Nursing Services in South East Scotland:A mixed methods impact and ouotcome research study 

    E-Print Network [OSTI]

    MacArthur, Juliet; Brown, Michael; Hayes, Matt; Mack, Siobhan; McKechanie, Andrew; Fletcher, Joan; Gibbs, Susie; Wilkinson, Heather

    To explore and identify the impact of Learning Disability Liaison Nursing (LDLN) Services in NHS Lothian, Forth Valley, Borders and Fife on the healthcare experiences of people with a learning disability attending for ...

  14. Learning Disability Liaising Nursing Services in South East Scotland: A mixed methods impact and outcome research study 

    E-Print Network [OSTI]

    MacArthur, Juliet; Brown, Michael; Hayes, Matt; Mack, Siobhan; McKechanie, Andrew; Fletcher, Joan; Gibbs, Susie; Wilkinson, Heather

    To explore and identify the impact of Learning Disability Liaison Nursing (LDLN) Services in NHS Lothian, Forth Valley, Borders and Fife on the healthcare experiences of people with a learning disability attending for ...

  15. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University/III study of 475 extremely preterm babies at 15 medical centers across the country. www.chdd.washington.edu/outlook/CHDD_Outlook Shriver Intellectual and Developmental Disabilities Research Center. CHDD Outlook Center on Human

  16. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University, and several studies have shown the positive effects of PFR on at-risk populations. www.chdd.washington.edu/outlook/CHDD_Outlook Center. CHDD Outlook Center on Human Development and Disability, University of Washington, Box 357920

  17. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University to MS, and our hypothesis is that a small number of people www.chdd.washington.edu/outlook/CHDD_Outlook and the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center. CHDD Outlook Center

  18. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University ages. www.chdd.washington.edu/outlook/CHDD_Outlook_2012_7.pdf 2012 Issue #7 Colin Studholme is leading Center. CHDD Outlook Center on Human Development and Disability, University of Washington, Box 357920

  19. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University matter. As a consequence, drugs that proved useful in rodent models failed in clinical trials. www.chdd.washington.edu/outlook/Outlook and the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center. CHDD Outlook Center

  20. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University, in particular N-acetylaspartate, (NAA), measured at very low levels in the children with autism, as www.chdd.washington.edu/outlook/CHDD_Outlook Center. CHDD Outlook Center on Human Development and Disability, University of Washington, Box 357920

  1. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University." www.chdd.washington.edu/outlook/Outlook_2010-Issue5.html 2010 Issue #6 #12;CHDD Center. CHDD Outlook Center on Human Development and Disability, University of Washington, Box 357920

  2. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University during cerebellar development. We are finding more and more types of cerebellar www.chdd.washington.edu/outlook/CHDD_Outlook and the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center. CHDD Outlook Center

  3. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University used by high-performing athletes for a different purpose in what is called "blood-doping." www.chdd.washington.edu/outlook/CHDD_Outlook Center. CHDD Outlook Center on Human Development and Disability, University of Washington, Box 357920

  4. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University, is charged with serving the poorest preschool-age children in the country www.chdd.washington.edu/outlook/Outlook Shriver Intellectual and Developmental Disabilities Research Center. CHDD Outlook Center on Human

  5. CHDD Outlook News from the Center on Human Development and Disability at the University of Washington

    E-Print Network [OSTI]

    CHDD Outlook News from the Center on Human Development and Disability at the University's interdisciplinary team approach is well-suited for seeing children with significant www.chdd.washington.edu/outlook/CHDD_Outlook and the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center. CHDD Outlook Center

  6. Disability Resources and Educational Services (DRES) University of Illinois, Champaign/Urbana

    E-Print Network [OSTI]

    Chen, Deming

    Disability Resources and Educational Services (DRES) University of Illinois, Champaign and Educational Services (DRES) within the College of Applied Health Science. As a unit that coordinates accommodations and services for students with disabilities, we receive a great deal of requests for our staff

  7. Learning disabilities in Costa Rica: Challenges for "an army of teachers." 

    E-Print Network [OSTI]

    s, Laura

    1997-01-01

    stream_source_info Learning Disabilities in Costa Rica-Challenges for an army of teachers.pdf.txt stream_content_type text/plain stream_size 6 Content-Encoding ISO-8859-1 stream_name Learning Disabilities in Costa Rica...

  8. Diaphragm as an anatomic surrogate for lung tumor motion

    E-Print Network [OSTI]

    Cervino, Laura I; Sandhu, Ajay; Jiang, Steve B

    2009-01-01

    Lung tumor motion due to respiration poses a challenge in the application of modern three-dimensional conformal radiotherapy. Direct tracking of the lung tumor during radiation therapy is very difficult without implanted fiducial markers. Indirect tracking relies on the correlation of the tumor's motion and the surrogate's motion. The present paper presents an analysis of the correlation between the tumor motion and the diaphragm motion in order to evaluate the potential use of diaphragm as a surrogate for tumor motion. We have analyzed the correlation between diaphragm motion and superior-inferior lung tumor motion in 32 fluoroscopic image sequences from 10 lung cancer patients. A simple linear model and a more complex linear model that accounts for phase delays between the two motions have been used. Results show that the diaphragm is a good surrogate for tumor motion prediction for most patients, resulting in an average correlation factor of 0.94 and 0.98 with each model respectively. The model that accoun...

  9. Modifications of lung clearance mechanisms by acute influenza A infection

    SciTech Connect (OSTI)

    Levandowski, R.A.; Gerrity, T.R.; Garrard, C.S.

    1985-10-01

    Four volunteers with naturally acquired, culture-proved influenza A infection inhaled a radiolabeled aerosol to permit investigation of lung mucociliary clearance mechanisms during and after symptomatic illness. Mucus transport in the trachea was undetectable when monitored with an external multidetector probe within 48 hours of the onset of the illness, but was found at a normal velocity by 1 week in three of the four subjects. In two volunteers who coughed 23 to 48 times during the 4.5-hour observation period, whole lung clearance was as fast within the first 48 hours of illness as during health 3 months later in spite of the absence of measurable tracheal mucus transport. Conversely, in spite of the return 1 week later of mucus transport at velocities expected in the trachea, whole lung clearance for the 4.5-hour period was slowed in two volunteers who coughed less than once an hour. The data offer evidence that cough is important in maintaining lung clearance for at least several days after symptomatic influenza A infection when other mechanisms that depend on ciliary function are severely deficient.

  10. Thermodynamics and evaporation of the noncommutative black hole

    E-Print Network [OSTI]

    Yun Soo Myung; Yong-Wan Kim; Young-Jai Park

    2007-01-21

    We investigate the thermodynamics of the noncommutative black hole whose static picture is similar to that of the nonsingular black hole known as the de Sitter-Schwarzschild black hole. It turns out that the final remnant of extremal black hole is a thermodynamically stable object. We describe the evaporation process of this black hole by using the noncommutativity-corrected Vaidya metric. It is found that there exists a close relationship between thermodynamic approach and evaporation process.

  11. Energy of 4-Dimensional Black Hole, etc

    E-Print Network [OSTI]

    Dmitriy Palatnik

    2011-07-18

    In this letter I suggest possible redefinition of mass density, not depending on speed of the mass element, which leads to a more simple stress-energy for an object. I calculate energy of black hole.

  12. Horizon Operator Approach to Black Hole Quantization

    E-Print Network [OSTI]

    G. 't Hooft

    1994-02-21

    The $S$-matrix Ansatz for the construction of a quantum theory of black holes is further exploited. We first note that treating the metric tensor $g_{\\m\

  13. Topological Black Holes -- Outside Looking In

    E-Print Network [OSTI]

    R. B. Mann

    1997-09-15

    I describe the general mathematical construction and physical picture of topological black holes, which are black holes whose event horizons are surfaces of non-trivial topology. The construction is carried out in an arbitrary number of dimensions, and includes all known special cases which have appeared before in the literature. I describe the basic features of massive charged topological black holes in $(3+1)$ dimensions, from both an exterior and interior point of view. To investigate their interiors, it is necessary to understand the radiative falloff behaviour of a given massless field at late times in the background of a topological black hole. I describe the results of a numerical investigation of such behaviour for a conformally coupled scalar field. Significant differences emerge between spherical and higher genus topologies.

  14. Evidence for the Black Hole Event Horizon

    E-Print Network [OSTI]

    Ramesh Narayan; Jeremy S. Heyl

    2002-04-26

    Roughly a dozen X-ray binaries are presently known in which the compact accreting primary stars are too massive to be neutron stars. These primaries are identified as black holes, though there is as yet no definite proof that any of the candidate black holes actually possesses an event horizon. We discuss how Type I X-ray bursts may be used to verify the presence of the event horizon in these objects. Type I bursts are caused by thermonuclear explosions when gas accretes onto a compact star. The bursts are commonly seen in many neutron star X-ray binaries, but they have never been seen in any black hole X-ray binary. Our model calculations indicate that black hole candidates ought to burst frequently if they have surfaces. Based on this, we argue that the lack of bursts constitutes strong evidence for the presence of event horizons in these objects.

  15. CHARYBDIS: A Black hole event generator.

    E-Print Network [OSTI]

    Harris, Chris M.; Richardson, P.; Webber, Bryan R.

    CHARYBDIS is an event generator which simulates the production and decay of miniature black holes at hadronic colliders as might be possible in certain extra dimension models. It interfaces via the Les Houches accord to general purpose Monte...

  16. Spacetime constraints on accreting black holes

    SciTech Connect (OSTI)

    Garofalo, David [Jet Propulsion Laboratory, California Institute of Technology, Pasadena California 91109 (United States)

    2009-06-15

    We study the spin dependence of accretion onto rotating Kerr black holes using analytic techniques. In its linear regime, angular momentum transport in MHD turbulent accretion flow involves the generation of radial magnetic field connecting plasma in a differentially rotating flow. We take a first principles approach, highlighting the constraint that limits the generation and amplification of radial magnetic fields, stemming from the transfer of energy from mechanical to magnetic form. Because the energy transferred in magnetic form is ultimately constrained by gravitational potential energy or Killing energy, the spin dependence of the latter allows us to derive spin-dependent constraints on the success of the accreting plasma to expel its angular momentum. We find an inverse relationship between this ability and black hole spin. If this radial magnetic field generation forms the basis for angular momentum transfer in accretion flows, accretion rates involving Kerr black holes are expected to be lower as the black hole spin increases in the prograde sense.

  17. Black Hills Energy- Solar Power Program

    Broader source: Energy.gov [DOE]

    All incentive payments are subject to the availability of funds and a pre-installation site inspection. Black Hills Energy has established participation caps for each tier. The status of funding ...

  18. Request for Disability Housing/Dining Accommodations www.rochester.edu/eoc/HousingDining.html Reviewed: 5/16/2013

    E-Print Network [OSTI]

    Cantlon, Jessica F.

    Request for Disability Housing/Dining Accommodations www.rochester.edu/eoc/HousingDining.html Reviewed: 5/16/2013 REQUEST FOR DISABILITY HOUSING AND DINING ACCOMMODATIONS Please complete this form://www.rochester.edu/eoc/hdaccommodation.html for detailed information regarding requesting disability-related housing or dining accommodations, including

  19. Classical and thermodynamic stability of black holes

    E-Print Network [OSTI]

    Monteiro, Ricardo

    2010-07-06

    Perturbations of the asymptotic charges . . . . . . . . . . . . . . . . 169 IV Conclusion 171 9 Conclusion and outlook 173 A Spectral numerical method 177 2 CONTENTS Part I Introduction 3 Chapter 1 Black holes Black holes are arguably the most interesting... to Newto- nian dynamics in the Solar system, and the indirect detection of gravitational waves from binary pulsars [1]. A crucial distinction from Newtonian gravity is that the “action-at-a-distance” is substituted by a built-in causality structure...

  20. Charged Cylindrical Black Holes in Conformal Gravity

    E-Print Network [OSTI]

    Jackson Levi Said; Joseph Sultana; Kristian Zarb Adami

    2013-01-04

    Considering cylindrical topology we present the static solution for a charged black hole in conformal gravity. We show that unlike the general relativistic case there are two different solutions, both including a factor that when set to zero recovers the familiar static charged black string solution in Einstein's theory. This factor gives rise to a linear term in the potential that also features in the neutral case and may have significant ramifications for particle trajectories.