Sample records for biology governmentally designated

  1. Modular design of biological systems

    E-Print Network [OSTI]

    Norville, Julie Erin, 1980-

    2012-01-01T23:59:59.000Z

    The focus of my research is the development of technology for building compound biological systems from simpler pieces. I designed BioScaffold parts, a family of variable regions that can be inserted into a DNA sequence ...

  2. Experiment design for systems biology

    E-Print Network [OSTI]

    Apgar, Joshua Farley

    2009-01-01T23:59:59.000Z

    Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. ...

  3. The living commons : a spatial theory for biological design

    E-Print Network [OSTI]

    Telhan, Orkan

    2013-01-01T23:59:59.000Z

    Biological design is as ancient as human civilization. For thousands of years, living systems and natural processes have been manipulated by humans and their biological outcomes have been customized for different purposes. ...

  4. Biological Development model for the Design of Robust Digital System

    E-Print Network [OSTI]

    Fernandez, Thomas

    Biological Development model for the Design of Robust Digital System Heng Liu Doctor of Philosophy and Keywords i Abstract This thesis presents a biologically-inspired developmental model for the design. The methods presented have been applied to produce a self-repairing two bit multiplier and an autonomous robot

  5. Rethinking Governmentality: Towards Genealogies of Governance

    E-Print Network [OSTI]

    Bevir, Mark

    2010-01-01T23:59:59.000Z

    M (1984) ‘Nietzsche, Genealogy, History’, in P Rabinow (Press. Biebricher T (2008) ‘Genealogy and Governmentality’,R. Schacht (ed. ) Nietzsche, Genealogy, Morality: Essays on

  6. A Platform-Based Design Environment for Synthetic Biological Systems

    E-Print Network [OSTI]

    Densmore, Douglas

    in drug pro- duction, biofuels, and drug delivery vessels. In an attempt to standardize this process, and the notion of both "top down" and "bottom up" design styles. 1.1 Requirements In the world of biology one can

  7. Bill Reis Named Vice President, Public & Governmental Affairs...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bill Reis Named Vice ... Bill Reis Named Vice President, Public & Governmental Affairs Posted: October 30, 2013 - 10:15am Bill Reis, Vice President, Public & Governmental Affairs...

  8. Before the Senate Homeland Security and Governmental Affairs...

    Energy Savers [EERE]

    and Governmental Affairs Subcommittee on Federal Financial Management, Government Information, Federal Services, and International Security Before the Senate Homeland...

  9. Governmental-Owner Power Imbalance and Privatization

    E-Print Network [OSTI]

    Xu, Kehan

    2011-10-21T23:59:59.000Z

    fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Approved by: Chair of Committee, Laszlo Tihanyi Committee Members, Michael Hitt Lorraine Eden Allan (Haipeng) Chen Head of Department, Murray Barrick August 2010... Major Subject: Management iii ABSTRACT Governmental-Owner Power Imbalance and Privatization. (August 2010) Kehan Xu, B.S., China Criminal Police College; M.B.A., University of Miami Chair of Advisory Committee: Dr. Laszlo Tihanyi...

  10. Removal design report for the 108-F Biological Laboratory

    SciTech Connect (OSTI)

    NONE

    1997-09-01T23:59:59.000Z

    Most of the 100-F facilities were deactivated with the reactor and have since been demolished. Of the dozen or so reactor-related structures, only the 105-F Reactor Building and the 108-F Biology Laboratory remain standing today. The 108-F Biology Laboratory was intended to be used as a facility for the mixing and addition of chemicals used in the treatment of the reactor cooling water. Shortly after F Reactor began operation, it was determined that the facility was not needed for this purpose. In 1949, the building was converted for use as a biological laboratory. In 1962, the lab was expanded by adding a three-story annex to the original four-story structure. The resulting lab had a floor area of approximately 2,883 m{sup 2} (main building and annex) that operated until 1973. The building contained 47 laboratories, a number of small offices, a conference room, administrative section, lunch and locker rooms, and a heavily shielded, high-energy exposure cell. The purpose of this removal design report is to establish the methods of decontamination and decommissioning and the supporting functions associated with facility removal and disposal.

  11. Apps for Energy Non-Governmental Resource Disclaimer

    Broader source: Energy.gov [DOE]

    The non-governmental resources are provided strictly for education purposes, and should not be considered a complete list of available resources.

  12. 2002 DOE Final Inherently Governmental and Commercial Activities...

    Energy Savers [EERE]

    Inherently Governmental and Commercial Activities Inventory More Documents & Publications DOE FAIR 2007 (OMB).xls 2003 DOE IGCA Inventory Data for web.xls&0; OMBDOEFAIR2005.xls...

  13. Procedure for developing biological input for the design, location, or modification of water-intake structures

    SciTech Connect (OSTI)

    Neitzel, D.A.; McKenzie, D.H.

    1981-12-01T23:59:59.000Z

    To minimize adverse impact on aquatic ecosystems resulting from the operation of water intake structures, design engineers must have relevant information on the behavior, physiology and ecology of local fish and shellfish. Identification of stimulus/response relationships and the environmental factors that influence them is the first step in incorporating biological information in the design, location or modification of water intake structures. A procedure is presented in this document for providing biological input to engineers who are designing, locating or modifying a water intake structure. The authors discuss sources of stimuli at water intakes, historical approaches in assessing potential/actual impact and review biological information needed for intake design.

  14. Simulation and optimization tools to study design principles of biological networks

    E-Print Network [OSTI]

    Adiwijaya, Bambang Senoaji

    2006-01-01T23:59:59.000Z

    Recent studies have developed preliminary wiring diagrams for a number of important biological networks. However, the design principles governing the construction and operation of these networks remain mostly unknown. To ...

  15. Biologically Inspired Algorithms for Micro and Nano System Design

    E-Print Network [OSTI]

    Mazumder, Pinaki

    .Elements. CAD Design Environment Changed from Uni-processor (Vax) N k f W k i (N W) Network of Workstations (NOW Design Environment Changed from Uni-processor (Vax) To Network of Workstations (NOW) Network

  16. Plutonium distribution: Summary of public and governmental support issues

    SciTech Connect (OSTI)

    Pasternak, A.

    1995-03-31T23:59:59.000Z

    Obtaining strong public and governmental support for the plutonium disposition program and for the projects comprising the selected disposition options will be essential to the success of the program in meeting non-proliferation goals established as national policy. This paper summarizes issues related to public and governmental support for plutonium disposition. Recommendations are offered which rest on two fundamental assumptions: (1) public and political support derive from public trust and confidence, and (2) despite widespread support for U.S. non-proliferation goals, establishing and operating facilities to carry out the program will entail controversy. Documentation for the Administration`s policy on non-proliferation as it relates to plutonium disposition is cited and summarized as background for ongoing planning efforts by the Department of Energy (DOE). Consensus is a reasonable goal for efforts to secure public and governmental support for the plutonium disposition program and its elements; unanimity is very unlikely. The program will be aided by the popular recognition of the importance of the nation`s non-proliferation goals, the potential for an energy dividend if an energy production option is selected ({open_quotes}Swords to Plowshares{close_quotes} metaphor), the possibility of influencing disposition decisions in other countries, and the clear need to do something with the excess material ({open_quotes}the no action alternative{close_quotes} will not suffice).

  17. Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiological andU.S.Biology

  18. Biologic

    E-Print Network [OSTI]

    Louis H. Kauffman

    2002-04-03T23:59:59.000Z

    In this paper we explore the boundary between biology and the study of formal systems (logic). In the end, we arrive at a summary formalism, a chapter in "boundary mathematics" where there are not only containers but also extainers >protein folding and the basic structure of the Temperley Lieb algebra at the foundations of topological invariants of knots and links.

  19. Strategies for Assessment of the Biological Performance and Design of Hydroturbines

    SciTech Connect (OSTI)

    Carlson, Thomas J.; Richmond, Marshall C.

    2011-05-05T23:59:59.000Z

    The biological response of fish to turbine passage has been of concern for several decades and emphasized recently by consideration of hydro as a 'green' power source. The current state-of-the-art of hydro-turbine biological performance assessment, while still inadequate, has advanced considerably the past 10 years. For example, the importance of assessment of exposure to pressure changes during turbine passage has been emphasized by findings of laboratory studies of rapid decompression. It is now very clear that hydroturbine biological assessment must consider the physiological state and behavior of fish at turbine entry and changes in physiological state that drive aspects of behavior during tailrace passage. Such considerations are in addition to concerns about exposure of fish to mechanical and pressure sources of injury during turbine passage. Experimental designs and assessment tools have evolved for acclimation of test fish, observation of test fish behavior at approach and upon exit from the turbine environment, and precise estimation of turbine passage mortality. Fish condition assessment continues to improve permitting better classification of observed injuries to injury mechanisms. Computational fluid dynamics (CFD) models and other computer models permit detailed investigation of the turbine passage environment and development of hypotheses that can be tested in field studies using live fish. Risk assessment techniques permit synthesis of laboratory and in-field study findings and estimation of population level effects over a wide range of turbine operation scenarios. Risk assessment is also evolving to provide input to turbine runner design. These developments, and others, have resulted in more productive biological performance assessment studies and will continue to evolve and improve the quantity and quality of information obtained from costly live fish hydroturbine passage studies. This paper reviews the history of hydro-turbine biological assessment, presents the current state-of-the-art, and identify areas needing improvement.

  20. Design Tools to Assess Hydro-Turbine Biological Performance: Priest Rapids Dam Turbine Replacement Project

    SciTech Connect (OSTI)

    Richmond, Marshall C.; Rakowski, Cynthia L.; Serkowski, John A.; Strickler, Brad; Weisbeck, Molly; Dotson, Curtis L.

    2013-06-25T23:59:59.000Z

    Over the past two decades, there have been many studies describing injury mechanisms associated with turbine passage, the response of various fish species to these mechanisms, and the probability of survival through dams. Although developing tools to design turbines that improve passage survival has been difficult and slow, a more robust quantification of the turbine environment has emerged through integrating physical model data, fish survival data, and computational fluid dynamics (CFD) studies. Grant County Public Utility District (GCPUD) operates the Priest Rapids Dam (PRD), a hydroelectric facility on the Columbia River in Washington State. The dam contains 10 Kaplan-type turbine units that are now almost 50 years old. The Utility District plans to refit all of these aging turbines with new turbines. The Columbia River at PRD is a migratory pathway for several species of juvenile and adult salmonids, so passage of fish through the dam is a major consideration when replacing the turbines. In this presentation, a method for turbine biological performance assessment (BioPA) is introduced. Using this method, a suite of biological performance indicators is computed based on simulated data from a CFD model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. Using known relationships between the dose of an injury mechanism and frequency of injury (dose–response) from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from proposed designs, the engineer can identify the more-promising alternatives. We will present application of the BioPA method for baseline risk assessment calculations for the existing Kaplan turbines at PRD that will be used as the minimum biological performance that a proposed new design must achieve.

  1. Structure of a Designed, Right-Handed Coiled-Coil Tetramer Containing All Biological Amino Acids

    SciTech Connect (OSTI)

    Sales, M.; Plecs, J.J.; Holton, J.M.; Alber, T.

    2009-06-04T23:59:59.000Z

    The previous design of an unprecedented family of two-, three-, and four-helical, right-handed coiled coils utilized nonbiological amino acids to efficiently pack spaces in the oligomer cores. Here we show that a stable, right-handed parallel tetrameric coiled coil, called RH4B, can be designed entirely using biological amino acids. The X-ray crystal structure of RH4B was determined to 1.1 {angstrom} resolution using a designed metal binding site to coordinate a single Yb{sup 2+} ion per 33-amino acid polypeptide chain. The resulting experimental phases were particularly accurate, and the experimental electron density map provided an especially clear, unbiased view of the molecule. The RH4B structure closely matched the design, with equivalent core rotamers and an overall root-mean-square deviation for the N-terminal repeat of the tetramer of 0.24 {angstrom}. The clarity and resolution of the electron density map, however, revealed alternate rotamers and structural differences between the three sequence repeats in the molecule. These results suggest that the RH4B structure populates an unanticipated variety of structures.

  2. Designing Biological Systems for Sustainability and Programmed Environmental Interface (2011 JGI User Meeting)

    ScienceCinema (OSTI)

    Silver, Pam [Harvard University

    2011-06-03T23:59:59.000Z

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Pam Silver of Harvard University gives a presentation on "Designing Biological Systems for Sustainability and Programmed Environmental Interface" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  3. Designing Biological Systems for Sustainability and Programmed Environmental Interface (2011 JGI User Meeting)

    SciTech Connect (OSTI)

    Silver, Pam [Harvard University] [Harvard University

    2011-03-23T23:59:59.000Z

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Pam Silver of Harvard University gives a presentation on "Designing Biological Systems for Sustainability and Programmed Environmental Interface" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  4. Strategies for designing, testing and demonstrating safety : what synthetic biology can learn from retrospective cases

    E-Print Network [OSTI]

    Yeddanapudi, Neelima, 1976-

    2009-01-01T23:59:59.000Z

    Synthetic biology is an emerging technology field within the realm of genetic engineering, differing from traditional genetic engineering in that it focuses on the modularization of genetic parts and the creation of de ...

  5. Developing governmental decision strategies for determining involvement in highly uncertain, large-scale capital investment projects

    E-Print Network [OSTI]

    Golden, Robert J

    1978-01-01T23:59:59.000Z

    to the project. Finally, in order to test the model's applicability in assisting governmental decision-makers to rationally allocate resources, the model has been empirically tested by a Westinghouse proposal (concerning offshore floating nuclear power... . Classification of Models . Models as a Frame of Reference The Contextual Matrix Development of the Matrix Model Methodology Exmployed to Utilize ~ ~ ~ ~ the 27 29 30 32 33 Matrix Framework . IV. WESTINGHOUSE'S OFFSHORE FLOATING NUCLEAR POWER PLANT...

  6. Biological determinants of photobioreactor design. Quarterly report No. 7, April 1, 1995--June 30, 1995

    SciTech Connect (OSTI)

    Palsson, B.O.; Brown, G.G.

    1997-04-01T23:59:59.000Z

    The photosynthetic conversion of light energy into algal biomass in large-scale cultures is controlled by the availability of light, the photosynthetic machinery of algae, nutrients, temperature and the design characteristics of the culture system. For the situation in which light is made the growth rate limiting factor, there is an upper limit in the light conversion efficiency of a large-scale culture, which translates to a maximum potential yield of 30-40 g dry weight m-2 day-1 under ideal light conditions. The development of large-scale mass cultures involves many considerations, but the two major design parameters for optimizing yields at a particular time are the flow rate throughout the culture and the depth of the culture.

  7. Biological determinants of photobioreactor design. Final report, September 1, 1993--August 31, 1995

    SciTech Connect (OSTI)

    Palsson, B.; Brown, G.G.

    1997-04-01T23:59:59.000Z

    Microalgae is being considered for the capture and sequestration of CO{sub 2} from power-plant flue-gases. High productivity of microalgae is necessary to make this process cost effective compared to the conventional methods used for reducing CO{sub 2} levels in the atmosphere. This obviates the need for large-scale cultivation technologies and proper photobioreactor technology. The physical factors that influence the performance of a photoautotrophic microalgal culture are the quality and composition of light, inlet carbon dioxide concentration, nutrients, and secondary metabolites at high cell densities. In developing photobioreactor technology, balancing of biological processes to the physical rate process becomes important. The effect of various light compositions on the culture kinetics was studied. To determine the optimal composition, six wavelengths 470, 555, 560, 570, 580 and 605 nm, each supplemented with 680 nm of red light, were used to cultivate cultures. Based on the results obtained, it is concluded that a monochromatic red light of 680 nm is sufficient to obtain maximum capacity.

  8. Greening the invisible hand : how environmental non-governmental organizations (NGOs) succeed and fall in technology change

    E-Print Network [OSTI]

    Rossi, Mark S. (Mark Stephen), 1962-

    2003-01-01T23:59:59.000Z

    This dissertation examines how national environmental non-governmental organizations (NGOs) in Sweden and the United States (US) tried to diffuse cleaner production technologies in the pulp and paper industry from 1980-1998. ...

  9. POLICY FLASH 2015-31- Acquisition Letter No. AL 2015-06, Performance of Inherently Governmental and Critical Functions

    Broader source: Energy.gov [DOE]

    Attached is the final Acquisition Letter (AL) No. AL 2015-06, Performance of Inherently Governmental and Critical Functions, dated July 01, 2015. This AL provides guidance to DOE and NNSA HCAs and COs for implementing OFPP Policy Letter 11-01, Performance of Inherently Governmental and Critical Functions. The guidance included in this AL is intended to serve as interim guidance for DOE until such time as the Federal Acquisition Regulation (FAR) is amended to implement the Policy Letter in full detail.

  10. Biology 494 Biology Internship

    E-Print Network [OSTI]

    Wurtele, Eve Syrkin

    Biology 494 Biology Internship Guidelines The Biology Program encourages students to seek out and participate in internship opportunities that have a clear biological focus. Internships may be arranged may receive credit in Biology 494 (Biology Internship) for participation in internships, regardless

  11. The use of changing factors as part of the design of M.I.T. student activity facilities

    E-Print Network [OSTI]

    Williams, Brooke Naramore

    1992-01-01T23:59:59.000Z

    Architects and urban designers must respond to many changing factors in the design of complex projects. Economic, governmental, user needs, community group, technical, and social issues can cause change. In completion of ...

  12. Design, Syntheses and Biological Applications of Through-bond Energy Transfer Cassettes and Novel Non-covalently Cell Penetrating Peptides

    E-Print Network [OSTI]

    Han, Junyan

    2012-02-14T23:59:59.000Z

    ................................................................................. 54 1. Design and Synthesis of the pH Probe .................................... 55 2. Results and Discussion............................................................ 57 3. Conclusions................................................................................. 65 1. Introduction ............................................................................. 66 2. Synthesis of the Cassettes 22-25 ............................................. 73 3.Results and Discussion...

  13. Leadership Training, Inter-ethnic Conflict Management, and the Youth: A Case Study of One Non-Governmental Organization (NGO) in Nairobi, Kenya

    E-Print Network [OSTI]

    Mbutu, Paul

    2012-10-19T23:59:59.000Z

    While many non-governmental organizations provide leadership training in inter-ethnic conflict management to Kenyan youth, relatively little is known about what goes into such training. This dissertation is a case study illustrating how the training...

  14. Biological remediation of contaminated soils at Los Angeles Air Force Base: Facility design and engineering cost estimate

    SciTech Connect (OSTI)

    Montemagno, C.D.; Irvine, R.L.

    1990-08-01T23:59:59.000Z

    This report presents a system design for using bioremediation to treat contaminated soil at Fort MacArthur near Los Angeles, California. The soil was contaminated by petroleum products that leaked from two underground storage tanks. Laboratory studies indicated that, with the addition of water and nutrients, soil bacteria can reduce the petroleum content of the soils to levels that meet regulatory standards. The system design includes soil excavation, screening, and mixing; treatment in five soil-slurry/sequencing-batch reactors; and dewatering by a rapid-infiltration basin. System specifications and cost estimates are provided. 5 refs., 8 figs., 5 tabs.

  15. Feedstock Supply System Design and Economics for Conversion of Lignocellulosic Biomass to Hydrocarbon Fuels: Conversion Pathway: Biological Conversion of Sugars to Hydrocarbons The 2017 Design Case

    SciTech Connect (OSTI)

    Kevin Kenney; Kara G. Cafferty; Jacob J. Jacobson; Ian J Bonner; Garold L. Gresham; William A. Smith; David N. Thompson; Vicki S. Thompson; Jaya Shankar Tumuluru; Neal Yancey

    2013-09-01T23:59:59.000Z

    The U.S. Department of Energy promotes the production of a range of liquid fuels and fuel blendstocks from lignocellulosic biomass feedstocks by funding fundamental and applied research that advances the state of technology in biomass collection, conversion, and sustainability. As part of its involvement in this program, the Idaho National Laboratory (INL) investigates the feedstock logistics economics and sustainability of these fuels. Between 2000 and 2012, INL conducted a campaign to quantify the economics and sustainability of moving biomass from standing in the field or stand to the throat of the biomass conversion process. The goal of this program was to establish the current costs based on conventional equipment and processes, design improvements to the current system, and to mark annual improvements based on higher efficiencies or better designs. The 2012 programmatic target was to demonstrate a delivered biomass logistics cost of $35/dry ton. This goal was successfully achieved in 2012 by implementing field and process demonstration unit-scale data from harvest, collection, storage, preprocessing, handling, and transportation operations into INL’s biomass logistics model. Looking forward to 2017, the programmatic target is to supply biomass to the conversion facilities at a total cost of $80/dry ton and on specification with in-feed requirements. The goal of the 2017 Design Case is to enable expansion of biofuels production beyond highly productive resource areas by breaking the reliance of cost-competitive biofuel production on a single, abundant, low-cost feedstock. If this goal is not achieved, biofuel plants are destined to be small and/or clustered in select regions of the country that have a lock on low-cost feedstock. To put the 2017 cost target into perspective of past accomplishments of the cellulosic ethanol pathway, the $80 target encompasses total delivered feedstock cost, including both grower payment and logistics costs, while meeting all conversion in-feed quality targets. The 2012 $35 programmatic target included only logistics costs with a limited focus on biomass quality

  16. Process Design and Economics for the Conversion of Lignocellulosic Biomass to Hydrocarbons: Dilute-Acid and Enzymatic Deconstruction of Biomass to Sugars and Biological Conversion of Sugars to Hydrocarbons

    SciTech Connect (OSTI)

    Davis, R.; Tao, L.; Tan, E. C. D.; Biddy, M. J.; Beckham, G. T.; Scarlata, C.; Jacobson, J.; Cafferty, K.; Ross, J.; Lukas, J.; Knorr, D.; Schoen, P.

    2013-10-01T23:59:59.000Z

    This report describes one potential conversion process to hydrocarbon products by way of biological conversion of lingnocellulosic-dervied sugars. The process design converts biomass to a hydrocarbon intermediate, a free fatty acid, using dilute-acid pretreatement, enzymatic saccharification, and bioconversion. Ancillary areas--feed handling, hydrolysate conditioning, product recovery and upgrading (hydrotreating) to a final blendstock material, wastewater treatment, lignin combusion, and utilities--are also included in the design.

  17. Foundational platform for mammalian synthetic biology

    E-Print Network [OSTI]

    Davidsohn, Noah (Noah Justin)

    2013-01-01T23:59:59.000Z

    The emergent field of synthetic biology is different from many other biological engineering efforts, in that its roots, design principles, and forward engineering perspective have been adopted from electrical engineering ...

  18. SPECIAL ISSUE ON SYSTEMS BIOLOGY, JANUARY 2008 51 Stochastic Modeling and Control of Biological

    E-Print Network [OSTI]

    Pappas, George J.

    of modeling, abstraction, and control of a biological system, namely, the lactose regulation systemSPECIAL ISSUE ON SYSTEMS BIOLOGY, JANUARY 2008 51 Stochastic Modeling and Control of Biological for stochastic modeling, model abstraction, and controller design for a biological system. The first half

  19. Biological Safety

    Broader source: Energy.gov [DOE]

    The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

  20. Purdue extension Agricultural&Biological

    E-Print Network [OSTI]

    for an extended period and encourage biological treatment to minimize organic matter (BOD), nitrogenPurdue extension Don Jones Agricultural&Biological Engineering Alan Sutton AnimalSciences Purdue structures must be designed and managed to contain manure, wastewater, contaminated runoff, and ma- nure

  1. Preparing for Transfer Biological Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    Environmental Engineering Game Design Industrial Systems & Information Technology Information Science MaterialsPreparing for Transfer Majors: Biological Engineering Chemical Engineering Civil Engineering Computer Science Electrical & Computer Engineering Engineering Physics Environmental Engineering

  2. BIOLOGICAL SAFETY POLICY PROGRAM TOPICS

    E-Print Network [OSTI]

    Fang-Yen, Christopher

    research protocols involving hazardous materials, reviews construction design for safety features with or near biologically hazardous materials (infectious agents, biohazards or recombinant DNA). 1.3 "Infectious waste" or "biohazardous waste" is defined by the Pennsylvania Department of Environmental

  3. Extracting principles from biology for application to running robots

    E-Print Network [OSTI]

    Haberland, Matthew Daniel

    2014-01-01T23:59:59.000Z

    When millions of years of evolution suggest a particular design solution, we may be tempted to abandon traditional design methods and copy the biological example. However, biological solutions do not often translate directly ...

  4. Governmental Accounting & Auditing Update

    E-Print Network [OSTI]

    Lin, Xiaodong

    for TPAF & PERS Reduce Early Retirement Incentives Increase Employee Contributions for all funds to 8 indicators Reporting procedures in place 11 #12;Proposed Pension Reforms Raise Retirement Age to 65

  5. Systems Biology. | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology. Systems Biology. Abstract: The biology revolution over the last 50 years has been driven by the ascendancy of molecular biology. This was enthusiastically embraced by most...

  6. Graduate Programs in Plant Biology and

    E-Print Network [OSTI]

    Wildermuth, Mary C

    not re- biochemistry, cell and molecular biology (B22). pmb.berkeley.edu Plant&Microbial Biology #12;The to the environment will continue to fuel the expansion of plant research well into the future. The plant biology program focuses on contemporary ba- sic plant research, design of biotechnologies, and plant-microbe

  7. Optimal Conventional and Semi-Natural Treatments for the Upper Yakima Spring Chinook Salmon Supplementation Project; Treatment Definitions and Descriptions and Biological Specifications for Facility Design, 1995-1999 Final Report.

    SciTech Connect (OSTI)

    Hager, Robert C. (Hatchery Operations Consulting); Costello, Ronald J. (Mobrand Biometrics, Inc., Vashon Island, WA)

    1999-10-01T23:59:59.000Z

    This report describes the Yakima Fisheries Project facilities (Cle Elum Hatchery and acclimation satellites) which provide the mechanism to conduct state-of-the-art research for addressing questions about spring chinook supplementation strategies. The definition, descriptions, and specifications for the Yakima spring chinook supplementation program permit evaluation of alternative fish culture techniques that should yield improved methods and procedures to produce wild-like fish with higher survival that can be used to rebuild depleted spring chinook stocks of the Columbia River Basin. The definition and description of three experimental treatments, Optimal Conventional (OCT), Semi-Natural (SNT), Limited Semi-Natural (LSNT), and the biological specifications for facilities have been completed for the upper Yakima spring chinook salmon stock of the Yakima Fisheries Project. The task was performed by the Biological Specifications Work Group (BSWG) represented by Yakama Indian Nation, Washington Department of Fish and Wildlife, National Marine Fisheries Service, and Bonneville Power Administration. The control and experimental variables of the experimental treatments (OCT, SNT, and LSNT) are described in sufficient detail to assure that the fish culture facilities will be designed and operated as a production scale laboratory to produce and test supplemented upper Yakima spring chinook salmon. Product specifications of the treatment groups are proposed to serve as the generic templates for developing greater specificity for measurements of product attributes. These product specifications will be used to monitor and evaluate treatment effects, with respect to the biological response variables (post release survival, long-term fitness, reproductive success and ecological interactions).

  8. Biological preconcentrator

    DOE Patents [OSTI]

    Manginell, Ronald P. (Albuquerque, NM); Bunker, Bruce C. (Albuquerque, NM); Huber, Dale L. (Albuquerque, NM)

    2008-09-09T23:59:59.000Z

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  9. biology | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular Science Computing Facility: Quiet Wing Science Theme: Biosystem Dynamics & Design Terrestrial & Subsurface Ecosystems Energy Materials & Processes Atmospheric...

  10. Bioinformatics & Computational Biology

    E-Print Network [OSTI]

    Richner, Heinz

    Bioinformatics & Computational Biology Master of Science in Bioinformatics and Computational Biology (90 ECTS) Contact Information Programme administration Bioinformatics and Computational Biology.unifr.ch/msc Programme administration Bioinformatics and Computational Biology University of Bern Baltzerstrasse 6 CH

  11. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    . Williams Professor of Biomedical Informations and Co-Director, Yale Computational Biology & Bioinformatics co-director of the Yale Computational Biology and Bioinformatics Program. In addition to the KeckBiological Statistics and Computational Biology Seminar Series Dr. Mark B. Gerstein Albert L

  12. Testimony by J. William Currie, Ph.D Manager, Energy Systems Modernization Office, Battelle, Pacific Northwest Laboratories before The Senate Committee on Governmental Affairs Washington D.C.

    SciTech Connect (OSTI)

    Currie, J.W.

    1992-02-18T23:59:59.000Z

    This report consists of the testimony by J. William Currie, Manager, Energy Systems Modernization Office, Battelle, Pacific Northwest Laboratories before The Senate Committee on Governmental Affairs, Washington, DC on February 18, 1992. He states ``It is a pleasure to have the opportunity to talk with this distinguished committee about energy conservation technologies and policies, especially as they relate to federal energy use and the commercialization of energy-efficiency technologies. Clearly, using energy more efficiently offers the potential for tremendous cost savings and environmental benefits in the United States and throughout the rest of the world. The challenge, especially with regard to the federal sector, is to lay the foundation for ensuring that the citizens of our nation realize the maximum savings and environmental benefit over the long run. This is the primary focus of my comments today.``

  13. Testimony by J. William Currie, Ph. D Manager, Energy Systems Modernization Office, Battelle, Pacific Northwest Laboratories before The Senate Committee on Governmental Affairs Washington D. C

    SciTech Connect (OSTI)

    Currie, J.W.

    1992-02-18T23:59:59.000Z

    This report consists of the testimony by J. William Currie, Manager, Energy Systems Modernization Office, Battelle, Pacific Northwest Laboratories before The Senate Committee on Governmental Affairs, Washington, DC on February 18, 1992. He states It is a pleasure to have the opportunity to talk with this distinguished committee about energy conservation technologies and policies, especially as they relate to federal energy use and the commercialization of energy-efficiency technologies. Clearly, using energy more efficiently offers the potential for tremendous cost savings and environmental benefits in the United States and throughout the rest of the world. The challenge, especially with regard to the federal sector, is to lay the foundation for ensuring that the citizens of our nation realize the maximum savings and environmental benefit over the long run. This is the primary focus of my comments today.''

  14. Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options

    SciTech Connect (OSTI)

    Carter, Sarah R. [J. Craig Venter Institute; Rodemeyer, Michael [University of Virginia; Garfinkel, Michele S. [EMBO; Friedman, Robert M [J. Craig Venter Institute

    2014-05-01T23:59:59.000Z

    Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options Sarah R. Carter, Ph.D., J. Craig Venter Institute; Michael Rodemeyer, J.D., University of Virginia; Michele S. Garfinkel, Ph.D., EMBO; Robert M. Friedman, Ph.D., J. Craig Venter Institute In recent years, a range of genetic engineering techniques referred to as “synthetic biology” has significantly expanded the tool kit available to scientists and engineers, providing them with far greater capabilities to engineer organisms than previous techniques allowed. The field of synthetic biology includes the relatively new ability to synthesize long pieces of DNA from chemicals, as well as improved methods for genetic manipulation and design of genetic pathways to achieve more precise control of biological systems. These advances will help usher in a new generation of genetically engineered microbes, plants, and animals. The JCVI Policy Center team, along with researchers at the University of Virginia and EMBO, examined how well the current U.S. regulatory system for genetically engineered products will handle the near-term introduction of organisms engineered using synthetic biology. In particular, the focus was on those organisms intended to be used or grown directly in the environment, outside of a contained facility. The study concludes that the U.S. regulatory agencies have adequate legal authority to address most, but not all, potential environmental, health and safety concerns posed by these organisms. Such near-term products are likely to represent incremental changes rather than a marked departure from previous genetically engineered organisms. However, the study also identified two key challenges for the regulatory system, which are detailed in the report. First, USDA’s authority over genetically engineered plants depends on the use of an older engineering technique that is no longer necessary for many applications. The shift to synthetic biology and other newer genetic engineering techniques will leave many engineered plants without any pre-market regulatory review. Second, the number and diversity of engineered microbes for commercial use will increase in the near future, challenging EPA’s resources, expertise, and perhaps authority to regulate them. For each of these challenges, the report sets out a series of options, including an analysis of the advantages and disadvantages of each option from a variety of perspectives, for policy makers to consider. Policy responses will depend on the trade-offs chosen among competing considerations. This report, funded by the Department of Energy with additional funds from the Alfred P. Sloan Foundation, is the result of a two-year process that included interviews, commissioned background papers, discussions, and two workshops that sought input from a wide range of experts, including U.S. federal agency regulators, legal and science policy experts, representatives from the biotechnology indus¬try, and non-governmental organiza¬tions. This cross-section of views informed this report, but the conclusions are solely those of the authors. An Executive Summary, full Report, and background papers are available at: http://www.jcvi.org/cms/research/projects/synthetic-biology-and-the-us-biotechnology-regulatory-system/overview/

  15. Genomics-Bioinformatics Day: "Bioinformatics, Computational Biology, Systems Biology & Mathematical

    E-Print Network [OSTI]

    Goldschmidt, Christina

    3rd Genomics-Bioinformatics Day: "Bioinformatics, Computational Biology, Systems Biology on "Bioinformatics, Computational Biology, Systems Biology & Mathematical Biology: Their Relationship". Genomics, Bioinformatics, Computational Biology have a tremendous appeal and these fields have originated or grown

  16. Hydro Review: Computational Tools to Assess Turbine Biological...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to analyze the biological performance of proposed designs to help ensure the safety of fish passing through the turbines at the Priest Rapids Dam in Grant County, Washington....

  17. Bioinformatics Computational Biology

    E-Print Network [OSTI]

    Mayfield, John

    Bioinformatics and Computational Biology Interdepartmental Graduate Program GRADUATE STUDENT HANDBOOK FALL 2006 Bioinformatics and Computational Biology Interdepartmental Graduate Program GRADUATE STUDENT HANDBOOK FALL 2006 #12;1 Welcome to the Bioinformatics and Computational Biology (BCB) program

  18. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    Science and the Center for Computational Biology and Bioinformatics at Columbia University. Dr. PeBiological Statistics and Computational Biology Seminar Series Dr. Itsik Pe'er Associate Professor of Computer Science Columbia University Itsik Pe'er is an associate professor in the Department of Computer

  19. Microfluidics for quantitative biology

    E-Print Network [OSTI]

    Adler, Micha

    2012-01-01T23:59:59.000Z

    CALIFORNIA, SAN DIEGO Microfluidics for Quantitative BiologyChapter 1: Microfluidics.………………………………………………………..… 1 1.1OF THE DISSERTATION Microfluidics for Quantitative Biology

  20. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work...

  1. Gravitational and Space Biology 18(2) June 2005 11 WORMS IN SPACE? A MODEL BIOLOGICAL DOSIMETER

    E-Print Network [OSTI]

    Baillie, David

    is available about the biological consequences of solar flares. Biological systems are not simply passive potential for the design of a biological dosimeter. In this paper, we describe the advantages of this model about up-coming meetings, abstracts, in- house publications, researchers' contact information

  2. OOTW Force Design Tools

    SciTech Connect (OSTI)

    Bell, R.E.; Hartley, D.S.III; Packard, S.L.

    1999-05-01T23:59:59.000Z

    This report documents refined requirements for tools to aid the process of force design in Operations Other Than War (OOTWs). It recommends actions for the creation of one tool and work on other tools relating to mission planning. It also identifies the governmental agencies and commands with interests in each tool, from whom should come the user advisory groups overseeing the respective tool development activities. The understanding of OOTWs and their analytical support requirements has matured to the point where action can be taken in three areas: force design, collaborative analysis, and impact analysis. While the nature of the action and the length of time before complete results can be expected depends on the area, in each case the action should begin immediately. Force design for OOTWs is not a technically difficult process. Like force design for combat operations, it is a process of matching the capabilities of forces against the specified and implied tasks of the operation, considering the constraints of logistics, transport and force availabilities. However, there is a critical difference that restricts the usefulness of combat force design tools for OOTWs: the combat tools are built to infer non-combat capability requirements from combat capability requirements and cannot reverse the direction of the inference, as is required for OOTWs. Recently, OOTWs have played a larger role in force assessment, system effectiveness and tradeoff analysis, and concept and doctrine development and analysis. In the first Quadrennial Defense Review (QDR), each of the Services created its own OOTW force design tool. Unfortunately, the tools address different parts of the problem and do not coordinate the use of competing capabilities. These tools satisfied the immediate requirements of the QDR, but do not provide a long-term cost-effective solution.

  3. COGR Council on Governmental Relations

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S. Department ofJune 2,The BigSidingState6Report, March003MEAM,ofCO2COGR COUNCIL

  4. 2003 Synthetic Biology study

    E-Print Network [OSTI]

    Endy, Drew

    2007-08-14T23:59:59.000Z

    Biology is a technology for processing information, materials, and energy. As a technology platform, biological systems provide access to artifacts and processes across a range of scales (e.g., the ribosome is a programmable ...

  5. Biological Systems Facilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    encompasses the areas of priority pathogen detection, extremophile biology and genomics, biohydrometallurgy, biomass conversion, coal bioprocessing, biodegradation...

  6. Process Manual Biological & Agricultural

    E-Print Network [OSTI]

    Boas, Harold P.

    · · · · ·t t ·t ·t t t ·t . ~ t · · Process· Manual Biological & Agricultural Engineering MANUAL FOR THE BIOLOGICAL AND AGRICULTURAL ENGINEERING DEPARTMENT TexasA&MUniversity Article I. NAME The name ofthis organization shall be the Biological and Agricultural Engineering Department (abbreviated

  7. Computational Biology & Bioinformatics

    E-Print Network [OSTI]

    Johnson, Marcia K.

    Computational Biology & Bioinformatics at Yale An Interdepartmental PhD Program and a Track within://www.yale.edu/graduateschool/admissions/apply_online.html 2 #12;Introduction Computational Biology and Bioinformatics (CBB) is a rapidly developing multi experimentation. Computational and theoretical approaches to understanding biological systems provide an essential

  8. Computational Biology & Bioinformatics

    E-Print Network [OSTI]

    Computational Biology & Bioinformatics at Yale An Interdepartmental PhD Program and a Track within://www.yale.edu/graduateschool/admissions/apply_online.html #12;3 Introduction Computational Biology and Bioinformatics (CBB) is a rapidly developing multi experimentation. Computational and theoretical approaches to understanding biological systems provide an essential

  9. Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU Minimal genomes in bacterial Genera Dave Ussery European Conference on Synthetic Biology: Design 2007 #12;Comparative Microbial Genomics group Centerfor

  10. Biology's wires and motors : single-molecule mechanics of M13 bacteriophage and kinesin

    E-Print Network [OSTI]

    Khalil, Ahmad S. (Ahmad Samir), 1980-

    2009-01-01T23:59:59.000Z

    Nature serves as an inspiration for engineering design, and, conversely, engineering principles have helped to usher in a quantitative frontier of biology. This intricate interdependency between engineering and biology is ...

  11. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, J.M.; Palumbo, A.V.

    1998-09-15T23:59:59.000Z

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer. 2 figs.

  12. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, Janet M. (Ten Mile, TN); Palumbo, Anthony V. (Oak Ridge, TN)

    1998-01-01T23:59:59.000Z

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer.

  13. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2014-04-15T23:59:59.000Z

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  14. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

  15. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Focus Area team for Soil Metagenomics and Carbon Cycling develops and uses community genomics approaches to link the biological processes controlling belowground carbon storage...

  16. Syllabus-PHY315-1 Biological and Medical Physics

    E-Print Network [OSTI]

    Movileanu, Liviu

    Syllabus-PHY315-1 Syllabus Biological and Medical Physics PHY 315 - Spring 2014 Professor Dr. Liviu in this syllabus. Administrative Assistance Mrs. Patricia Whitmore; Office: Room111, Physics Bldg.; Phone: 443;Syllabus-PHY315-2 Contents of the class: Why biology by the numbers? Design schemes for cells

  17. Retroactivity, modularity, and insulation in synthetic biology circuits

    E-Print Network [OSTI]

    Lin, Allen

    2011-01-01T23:59:59.000Z

    A central concept in synthetic biology is the reuse of well-characterized modules. Modularity simplifies circuit design by allowing for the decomposition of systems into separate modules for individual construction. Complex ...

  18. 7.02 Introduction to Experimental Biology, Fall 2001

    E-Print Network [OSTI]

    Amon, Angelika

    7.02 and 7.021 require simultaneous registration. Application of experimental techniques in biochemistry, microbiology, and cell biology. Emphasizes integrating factual knowledge with understanding the design of experiments ...

  19. Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Environmental and Conservation Biology ­Conservation Biology Bachelor of Science [AS or upper division) 4 #12;Roadmap: Environmental and Conservation Biology ­Conservation Biology Bachelor Summary on page 2 Conservation Biology Concentration Elective 2 See note 3 on page 2 Semester Five: [15

  20. AGRICULTURAL AND BIOLOGICAL

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL AND BIOLOGICAL ENGINEERING UNDERGRADUATE PROGRAM Prepare... yourself for a career in integrating life and engineering for systems in agriculture, food, environment, and energy, and to contribute to the world's largest industry. COLLEGE OF ACES COLLEGE OF ENGINEERING #12;AGRICULTURAL AND BIOLOGICAL

  1. Human Embryology & Developmental Biology

    E-Print Network [OSTI]

    Levi, Ran

    Biology is the modern synthesis of biological and medical sciences that looks at how the tissues, and is at the forefront of recent advances in modern medicine. Current research has shown that many of the molecular Web Pages for names). The Head of School of Medical Sciences is always available for advice regarding

  2. Molecular Biology DEGREE PROGRAMME

    E-Print Network [OSTI]

    Levi, Ran

    to the course co-ordinator for that module (See University Catalogue of Courses or SMS World Wide Web Pages in molecular biology have a wide range of career options, including virtually all areas of biology, medicine with mastering statistics, graphics and word processing software packages. General Enquiries The Degree Programme

  3. From medical relief to community health care: A case study of a Non-Governmental Organisation (Frontier Primary Health Care) in North West Frontier Province, Pakistan 

    E-Print Network [OSTI]

    Patterson, Margaret Madeline

    This case study is designed to answer the question whether refugees can make a positive contribution to host countries, not simply as individual participants in economic activity, but by contributing to welfare. The ...

  4. Extracting information from biological networks

    E-Print Network [OSTI]

    Chindelevitch, Leonid Alexandrovich

    2010-01-01T23:59:59.000Z

    Systems biology, the study of biological systems in a holistic manner, has been catalyzed by a dramatic improvement in experimental techniques, coupled with a constantly increasing availability of biological data. The ...

  5. Master track Theoretical Biology & Bioinformatics

    E-Print Network [OSTI]

    Utrecht, Universiteit

    their master. Our two MSc courses "Computational Biology" and "Bioinformatics and Evolutionary GenomicsMaster track Theoretical Biology & Bioinformatics Modeling and bioinformatics is an important Biology & Bioinformatics provides courses introducing you to the basic concepts of modeling

  6. Viewing biology in action | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    biology in action Released: June 11, 2014 DOE-funded pilot program will create mesoscale biological imaging platform James Evans EMSL received first-year funding of almost...

  7. Todd Newberry: Professor of Biology

    E-Print Network [OSTI]

    Newberry, Andrew Todd; Jarrell, Randall; Regional History Project, UCSC Library

    2006-01-01T23:59:59.000Z

    Professor of Biology: Early Retirement page 44 Jarrell: ToProfessor of Biology: Early Retirement page 45 Jarrell: ToWar 33 Voluntary Early Retirement Incentive Program (VERIP)

  8. Biological Interactions and Dynamics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    proactive "EMSL 2.0-style" research paradigm. Because of the rapid pace of modern genomics and systems biology research, it is necessary to respond rapidly and flexibly to...

  9. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal...

  10. Computational Tools to Assess Turbine Biological Performance

    SciTech Connect (OSTI)

    Richmond, Marshall C.; Serkowski, John A.; Rakowski, Cynthia L.; Strickler, Brad; Weisbeck, Molly; Dotson, Curtis L.

    2014-07-24T23:59:59.000Z

    Public Utility District No. 2 of Grant County (GCPUD) operates the Priest Rapids Dam (PRD), a hydroelectric facility on the Columbia River in Washington State. The dam contains 10 Kaplan-type turbine units that are now more than 50 years old. Plans are underway to refit these aging turbines with new runners. The Columbia River at PRD is a migratory pathway for several species of juvenile and adult salmonids, so passage of fish through the dam is a major consideration when upgrading the turbines. In this paper, a method for turbine biological performance assessment (BioPA) is demonstrated. Using this method, a suite of biological performance indicators is computed based on simulated data from a CFD model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. Using known relationships between the dose of an injury mechanism and frequency of injury (dose–response) from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from proposed designs, the engineer can identify the more-promising alternatives. We present an application of the BioPA method for baseline risk assessment calculations for the existing Kaplan turbines at PRD that will be used as the minimum biological performance that a proposed new design must achieve.

  11. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect (OSTI)

    Galitski, Timothy P.

    2008-04-01T23:59:59.000Z

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  12. advanced rationally designed: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    zinc phosphide solar project and the knowledge he contributed Winfree, Erik 3 Rational Design of Zinc Phosphide Heterojunction Photovoltaics Biology and Medicine Websites Summary:...

  13. Process Design and Economics for the Conversion of Lignocellulosic Biomass to Hydrocarbons: Dilute-Acid and Enzymatic Deconstruction of Biomass to Sugars and Biological Conversion of Sugars to Hydrocarbons

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOrigin of ContaminationHubs+ Report Presentation:in the U.S. by 2030,PNNL-23227 Process Design

  14. Process Design and Economics for the Conversion of Lignocellulosic Biomass to Hydrocarbons: Dilute-Acid and Enzymatic Deconstruction of Biomass to Sugars and Biological Conversion of Sugars to Hydrocarbons

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible forPortsmouth/Paducah47,193.70 Hg Mercury 35 Br BromineProbing the5 thProcess Design and

  15. structural biology | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular Science Computing Facility: Quiet Wing Science Theme: Biosystem Dynamics & Design Terrestrial & Subsurface Ecosystems Energy Materials & Processes Atmospheric...

  16. Fishery Biology Graduate Programs

    E-Print Network [OSTI]

    Fishery Biology Graduate Programs University of Alaska Fairbanks, Alaska 997750820 Program/degrees/index.html University of Arizona Tucson, Arizona 95721 Program: Fisheries Conservation and Management http://ag.arizona.edu/srnr/academicprograms/wildlifefisheries/gradstudiesFisheries.html Auburn University Auburn, Alabama 368490001 Programs: Aquaculture, Aquatic Ecology, Fishery Management

  17. BIOLOGICAL ANALYSIS Mass Spectrometry

    E-Print Network [OSTI]

    Greenaway, Alan

    Microscope) Analytical Equipment · High Performance Liquid Chromatography · Fast Protein Liquid Chromatography · Gas Chromatography · GC/MS · Elemental Analyser Molecular Biology Equipment · Biorad PCR Machine reactor for scale up studies In-line Particle sizers Rheometers Separation tanks Oscillating column (4m

  18. Chemistry and Chemical Biology

    E-Print Network [OSTI]

    Linhardt, Robert J.

    and interdisciplinary areas, including biochemical solar energy research, artificial photosynthesis and bio Biology at Rensselaer invites applications from students interested in pursuing a Ph.D. degree in an interdisciplinary environment with research opportunities in emerging fields, such as energy and the environment

  19. Biological and Environmental

    E-Print Network [OSTI]

    and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. After capitalize on recent technological and scientific advances. Several multidisciplinary projects of key,ecosystemmonitoringandrestoration,combiningcropresearchandmicrobial engineering to make biofuels a viable alternative to fossil fuels, and personalized medicine to improve health

  20. Biological and Environmental Research

    E-Print Network [OSTI]

    recalcitrance. Using an integrated approach to solving the challenge of producing biofuel from cellulosic materials, the center will not only provide the scientific basis for affordable and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. BESC researchers have

  1. CANCER BIOLOGY Infectioustumourcells

    E-Print Network [OSTI]

    Nowak, Martin A.

    CANCER BIOLOGY Infectioustumourcells David Dingli and Martin A. Nowak Cancer cells are generally infectious agents and be transmitted between individuals. The current view of cancer development is that normal cells are transformed into tumour cells by sequential mutations that activate cancer- promoting

  2. ECOLOGY LABORATORY BIOLOGY 341

    E-Print Network [OSTI]

    Vonessen, Nikolaus

    Page 1 ECOLOGY LABORATORY BIOLOGY 341 Fall Semester 2008 Bighorn Sheep Rams at Bison Range National ecological data; and 3) oral and written communication skills. Thus, these ecology labs, and statistical analyses appropriate for ecological data. A major goal of this class will be for you to gain

  3. Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Environmental and Conservation Biology ­Conservation Biology Bachelor of Science [AS Geology Elective 3-4 See note 2 on page 2 General Elective 4 #12;Roadmap: Environmental and Conservation Summary on page 2 Conservation Biology Concentration Elective 2 See note 3 on page 2 Semester Five: [15

  4. Guest Editors' Introduction: Synthetic Biology

    E-Print Network [OSTI]

    Densmore, Douglas

    + undergraduate participants from around the world. Synthetic Biology had a global market which gene- rated $233 Tufts University h SYNTHETIC BIOLOGY IS trending, as evidenced by the recent achievements in biofuels

  5. Modular architecture in biological networks

    E-Print Network [OSTI]

    Ramachandran, Gopal (Gopal Sebastian)

    2007-01-01T23:59:59.000Z

    In the past decade, biology has been revolutionized by an explosion in the availability of data. Translating this new wealth of information into meaningful biological insights and clinical breakthroughs will require a ...

  6. Biological Engineering integrates life sciences

    E-Print Network [OSTI]

    Walter, M.Todd

    mitigating 40 million pounds of carbon dioxide greenhouse gases each year, and would pay for itself in les with the constantly evolving science of biology, the field of Biological Engineering tackles local, national

  7. Biological Interactions and Dynamics Workshop | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Interactions and Dynamics Workshop Biological Interactions and Dynamics Workshop Wiley HS, Kaplan S. 2011. "Biological Interactions and Dynamics Science Theme Advisory...

  8. 2013 Biological Hydrogen Production Workshop Summary Report ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Hydrogen Production Workshop Summary Report 2013 Biological Hydrogen Production Workshop Summary Report November 2013 summary report for the 2013 Biological Hydrogen...

  9. Environmental Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    microbiology, biogeochemistry, molecular biology, molecular dynamics, bioinformatics, genomics, neutron science, chemistry, and computing-and spans multiple scales, from the...

  10. Systems Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of interdisciplinary scientists. Additional systems biology resources Research Highlights Media Mentions Publications Newsletters Biosciences Division Recent news releases 11...

  11. Perspectives Computational Biology in Brazil

    E-Print Network [OSTI]

    Neshich, Goran

    Perspectives Computational Biology in Brazil Goran Neshich Introduction At the request of the PLoS Computational Biology Editor-in- Chief, I agreed to write about computational biology in Brazil (see author of the field itself is short); b) the current state of the field in Brazil; c) the influence of computational

  12. COMPUTATIONAL MOLECULAR BIOLOGY TRAINING PROGRAM

    E-Print Network [OSTI]

    Mayfield, John

    in the burgeoning fields of bioinformatics and computational biology. A major outcome of the initial funding period was the establishment of ISU's interdepartmental graduate program in Bioinformatics and Computational Biology (BCB for Research Excellence in Bioinformatics and Computational Biology (BCB). The ISU-NMSU partnership

  13. Biological particle identification apparatus

    DOE Patents [OSTI]

    Salzman, Gary C. (Los Alamos, NM); Gregg, Charles T. (Los Alamos, NM); Grace, W. Kevin (Los Alamos, NM); Hiebert, Richard D. (Los Alamos, NM)

    1989-01-01T23:59:59.000Z

    An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

  14. Anthro Arm : the design of a seven degree of freedom arm with human attributes

    E-Print Network [OSTI]

    Leeb, Adam Paul

    2007-01-01T23:59:59.000Z

    Studying biological systems has given robotics researchers valuable insight into designing complex systems. This thesis explores one such application of a biomimetic robotic system designed around a human arm. The design ...

  15. Radiation physics, biophysics, and radiation biology

    SciTech Connect (OSTI)

    Hall, E.J.

    1992-05-01T23:59:59.000Z

    The following research programs from the Center for Radiological Research of Columbia University are described: Design and development of a new wall-less ultra miniature proportional counter for nanodosimetry; some recent measurements of ionization distributions for heavy ions at nanometer site sizes with a wall-less proportional counter; a calculation of exciton energies in periodic systems with helical symmetry: application to a hydrogen fluoride chain; electron energy-loss function in polynucleotide and the question of plasmon excitation; a non-parametric, microdosimetric-based approach to the evaluation of the biological effects of low doses of ionizing radiation; high-LET radiation risk assessment at medium doses; high-LET radiobiological effects: increased lesion severity or increased lesion proximity; photoneutrons generated by high energy medical linacs; the biological effectiveness of neutrons; implications for radiation protection; molecular characterization of oncogenes induced by neutrons; and the inverse dose-rate effect for oncogenic transformation by charged particles is LET dependent.

  16. Biology and Medicine Division annual report, 1987

    SciTech Connect (OSTI)

    Not Available

    1988-04-01T23:59:59.000Z

    Modern biology is characterized by rapid change. The development of new tools and the results derived from their application to various biological systems require significant shifts in our concepts and the strategies that are adopted to analyze and elucidate mechanisms. In parallel with exciting new scientific developments our organizational structure and programmatic emphases have altered. These changes and developments have enabled the life sciences at LBL to be better positioned to create and respond to new opportunities. The work summarized in this annual report reflects a vital multifaceted research program that is in the vanguard of the areas represented. We are committed to justifying the confidence expressed by LBL through the new mission statement and reorganizational changes designed to give greater prominence to the life sciences.

  17. 7.013 Introductory Biology, Spring 2005

    E-Print Network [OSTI]

    Sive, Hazel L.

    The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological ...

  18. Autofermentative Biological Hydrogen Production by Cyanobacteria...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Autofermentative Biological Hydrogen Production by Cyanobacteria Autofermentative Biological Hydrogen Production by Cyanobacteria Presentation by Charles Dismukes, Rutgers...

  19. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiological and

  20. Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiologicalLaboratories

  1. Biologically inspired digital fabrication

    E-Print Network [OSTI]

    Han, Sarah (Sarah J.)

    2013-01-01T23:59:59.000Z

    Objects and systems in nature are models for the practice of sustainable design and fabrication. From trees to bones, natural systems are characterized by the constant interplay of creation, environmental response, and ...

  2. Biology reflective assessment curriculum

    E-Print Network [OSTI]

    Bayley, Cheryl Ann

    2011-01-01T23:59:59.000Z

    Curriculum Design) by Cheryl Ann Bayley Committee in charge:P. Halter Copyright Cheryl Ann Bayley, 2011 All rightsreserved. The Thesis of Cheryl Ann Bayley is approved and it

  3. Department of Systems Biology & Bioinformatics

    E-Print Network [OSTI]

    Rostock, Universität

    Department of Systems Biology & Bioinformatics Faculty of Computer Sciences & Electrical, comparability and fairness. Practical Aspects and Soft Skills Technical Achievement Background understanding

  4. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    Welcome to the Administrative section of the Biological and Environmental Research Abstracts Database. Please logon. Logon Name: Password: Logon CommentsEmail Us * Security...

  5. CollegeofScience Biological Sciences

    E-Print Network [OSTI]

    Hickman, Mark

    ,populations,and even ecosystems. Our courses will help prepare you for a career in biology,be it in biodiversity

  6. COMPLEX BIOLOGICAL MECHANISMS: CYCLIC, OSCILLATORY,

    E-Print Network [OSTI]

    Bechtel, William

    COMPLEX BIOLOGICAL MECHANISMS: CYCLIC, OSCILLATORY, AND AUTONOMOUS William Bechtel and Adele- nomological framework and its focus on laws as the primary explanatory vehicle; for them, a scientific

  7. Plant Vascular Biology 2010

    SciTech Connect (OSTI)

    Ding, Biao

    2014-11-17T23:59:59.000Z

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  8. Experience in Remote Demolition of the Activated Biological Shielding of the Multi Purpose Research Reactor (MZFR) on the German Karlsruhe Site - 12208

    SciTech Connect (OSTI)

    Eisenmann, Beata; Fleisch, Joachim; Prechtl, Erwin; Suessdorf, Werner; Urban, Manfred [WAK Rueckbau- und Entsorgungs- GmbH, P.O.Box 12 63, 76339 Eggenstein-Leopoldshafen (Germany)

    2012-07-01T23:59:59.000Z

    In 2009, WAK Decommissioning and Waste Management GmbH (WAK) became owner and operator of the waste treatment facilities of Karlsruhe Institute of Technology (KIT) as well as of the prototype reactors, the Compact Sodium-Cooled Fast Reactor (KNK) and Multi-Purpose Reactor (MZFR), both being in an advanced stage of dismantling. Together with the dismantling and decontamination activities of the former WAK reprocessing facility since 1990, the envisaged demolishing of the R and D reactor FR2 and a hot cell facility, all governmentally funded nuclear decommissioning projects on the Karlsruhe site are concentrated under the WAK management. The small space typical of prototype research reactors represented a challenge also during the last phase of activated dismantling, dismantling of the activated biological shield of the MZFR. Successful demolition of the biological shield required detailed planning and extensive testing in the years before. In view of the limited space and the ambient dose rate that was too high for manual work, it was required to find a tool carrier system to take up and control various demolition and dismantling tools in a remote manner. The strategy formulated in the concept of dismantling the biological shield by means of a modified electro-hydraulic demolition excavator in an adaptable working scaffolding turned out to be feasible. The following boundary conditions were essential: - Remote exchange of the dismantling and removal tools in smallest space. - Positioning of various supply facilities on the working platform. - Avoiding of interfering edges. - Optimization of mass flow (removal of the dismantled mass from the working area). - Maintenance in the surroundings of the dismantling area (in the controlled area). - Testing and qualification of the facilities and training of the staff. Both the dismantling technique chosen and the proceeding selected proved to be successful. Using various designs of universal cutters developed on the basis of wall saws, both the activated steel liner and the inner reinforcing layer were cut remotely in one process. This allowed for the efficient execution of the following remote concrete removal steps using mining techniques. The electro-hydraulic demolition excavator that was purchased and then modified turned out to be an ideal tool carrier system with rapid-exchange coupling. Due to the high availability, no major delays occurred. This also was a result of the consistently implemented maintenance and repair concept. With the excavator installed in a modifiable scaffolding suspended from a rotating carrier ring, all dismantling areas could be reached and treated in spite of the small space. Thanks to an optimum organization of work-flows, routine change of dismantling work, and maintenance or repair, the iterative radiological measurement campaigns could be integrated in the whole activity without the dismantling work being disturbed significantly. The ventilation system with pressure grading and pre-filtration units ensured a low contamination level in the dismantling area. It was also possible to manage the dust formed by the milling of concrete surfaces. As it was possible to further cut metal parts and crushed concrete later on, residue flows were optimized. The planned overall period for testing, dismantling the bio-shield and removing the equipment was 36 months. The final duration was 39 months. (authors)

  9. Governmental-Owner Power Imbalance and Privatization 

    E-Print Network [OSTI]

    Xu, Kehan

    2011-10-21T23:59:59.000Z

    natural research context to examine the function of capital markets, the impact of national institutional settings, and the differences between partial privatization and initial public offerings. Very little research, however, has examined the determinants...

  10. Frank Breust, Governmental Affairs,BMW Group

    E-Print Network [OSTI]

    California at Davis, University of

    kilometers ~1.100vehicles BMW i3 and BMW i8 BMW i is more than just an electric car. BMW i offers 360 + 95 hp electric motor #12;FULLY ELECTRIC CAR SHARING. DRIVENOW IN THE BAYAREA. On;FULLY ELECTRIC CAR SHARING. DRIVENOW IN THE BAYAREA. On-Street-Parking necessary for better visibility

  11. Hanford Tours for Governmental Officials - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) EnvironmentalGyroSolé(tm) Harmonicbet When yourecoveryG - SSC Data Summary

  12. Design and Syntheses of Dyes for Biological Applications

    E-Print Network [OSTI]

    Thivierge, Cliferson

    2012-07-16T23:59:59.000Z

    NF2BN N NH N HN N F2B N 5 N NH N HN NF2B N N F2B N 6 mes mes N NH N HN R R R R R = N B F2 N N F2B N 7 Figure 1.6 Continued. 15 Lindsey investigated the potential of systems like 1 as ?optoelectronic gates... by their inherent hydrophobicities. N BF2 N R = 8 !abs max 504 nm !em max 544 nm ETE 97 % R N BF2 N R N B F2 N O N H HO2C 9 !abs max 504 nm !em max 545 nm ETE 94 % R N B F2 N O SucO OMeMeO 10 !abs max 504 nm !em max 632 nm...

  13. Design and Syntheses of Dyes for Biological Applications 

    E-Print Network [OSTI]

    Thivierge, Cliferson

    2012-07-16T23:59:59.000Z

    is incorporated into conjugated polymers by random incorporation of BODIPY dyes into polyfluorenes. The ideal ratio of fluorene to BODIPY parts was found to be 4:1. The BODIPY doping agents result in dispersed emissions when excited the polyfluorene polymers...

  14. Staunton State Park Biological Inventory

    E-Print Network [OSTI]

    Staunton State Park Biological Inventory Prepared by: Susan Spackman, David Anderson, Jeremy Biological Inventory Prepared by: Susan Spackman, David Anderson, Jeremy Siemers, Phyllis Pineda, and Jill. The information management staff with CNHP was responsible for integrating the data resulting from the inventory

  15. FISHERY RESEARCH BIOLOGICAL LABORATORY, GALVESTON

    E-Print Network [OSTI]

    stations conduct fish ry re - search in the Gulf of Mexico as part of the work of the Bureau's Gulf, St. Pet rsburg Beach, Fla. Biological Res earch Biological Laboratory, Beaufort, N. C hw Gulf of Mexico Abundance of postlarval and juv nil shrimp Pink shrimp life history . Brown

  16. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology Visualisation of Large Amounts of Data Dave Ussery 27 February, 2008 #12;Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology #12;Comparative Microbial Genomics group

  17. Loop Quantum Theory Applied to Biology and Nonlinear Whole Biology

    E-Print Network [OSTI]

    Yi-Fang Chang

    2008-01-02T23:59:59.000Z

    The loop quantum theory, which constitutes a very small discontinuous space, as new method is applied to biology. The model of protein folding and lungs is proposed. In the model, some known results are used, and four approximate conclusions are obtained: their structures are quantized, their space regions are finite, various singularities correspond to folding and crossed points, and different types of catastrophe exist. Further, based on the inseparability and correlativity of the biological systems, the nonlinear whole biology is proposed, and four basic hypotheses are formed. It may unify reductionism and holism, structuralism and functionalism. Finally, the medical meaning of the theory is discussed briefly.

  18. Mesangial cell biology

    SciTech Connect (OSTI)

    Abboud, Hanna E., E-mail: Abboud@uthscsa.edu

    2012-05-15T23:59:59.000Z

    Mesangial cells originate from the metanephric mesenchyme and maintain structural integrity of the glomerular microvascular bed and mesangial matrix homeostasis. In response to metabolic, immunologic or hemodynamic injury, these cells undergo apoptosis or acquire an activated phenotype and undergo hypertrophy, proliferation with excessive production of matrix proteins, growth factors, chemokines and cytokines. These soluble factors exert autocrine and paracrine effects on the cells or on other glomerular cells, respectively. MCs are primary targets of immune-mediated glomerular diseases such as IGA nephropathy or metabolic diseases such as diabetes. MCs may also respond to injury that primarily involves podocytes and endothelial cells or to structural and genetic abnormalities of the glomerular basement membrane. Signal transduction and oxidant stress pathways are activated in MCs and likely represent integrated input from multiple mediators. Such responses are convenient targets for therapeutic intervention. Studies in cultured MCs should be supplemented with in vivo studies as well as examination of freshly isolated cells from normal and diseases glomeruli. In addition to ex vivo morphologic studies in kidney cortex, cells should be studied in their natural environment, isolated glomeruli or even tissue slices. Identification of a specific marker of MCs should help genetic manipulation as well as selective therapeutic targeting of these cells. Identification of biological responses of MCs that are not mediated by the renin–angiotensin system should help development of novel and effective therapeutic strategies to treat diseases characterized by MC pathology.

  19. Bacterial Community Structure in Geographically Distributed Biological

    E-Print Network [OSTI]

    Alvarez-Cohen, Lisa

    Bacterial Community Structure in Geographically Distributed Biological Wastewater Treatment of the microbial communities within biological wastewater treatment reactors is incomplete due to limitations microbial community composition in five biological wastewater treatment reactors in China and the United

  20. Introduction to Bioinformatics A Systems Biology Approach

    E-Print Network [OSTI]

    Rocha, Luis

    Introduction to Bioinformatics A Systems Biology Approach Luis M. Rocha Complex Systems Modeling Computational Biology to Bioinformatics Course Layout: March 11-15, 2002 #12;P Systems Biology P Synthetic, Multi- Disciplinary Approach

  1. Merging hydraulics with biology

    SciTech Connect (OSTI)

    Thorncraft, Garry; Baumgartner, Lee J.; Boys, Craig A.; Brown, Richard S.

    2013-01-01T23:59:59.000Z

    Research staff are now working with developers in Lao PDR and Australia to ensure design criteria is optimised at time of construction. Research is presently underway on a suite of Mekong and Murray-Darling species to identify critical tolerances of shear and pressure. Work in the USA is also being expanded to lamprey and white sturgeon in an effort to increase the understanding beyond salmon species. Researchers and developers are hopeful of constructing the first fish-friendly hydro plants within the next two years. Pending favourable outcomes, the expansion of this technology to other sites and river systems is the ultimate development outcome.

  2. DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida

    E-Print Network [OSTI]

    Kelly, John J.

    DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida (Photo Credit: Michael Masellis, Biology Major Hurricane Savitz Hits Florida Future Science Teachers' Club Recent Grant Successes Forthcoming Publications

  3. The sequestration efficiency of the biological pump

    E-Print Network [OSTI]

    DeVries, Tim; Primeau, Francois; Deutsch, Curtis

    2012-01-01T23:59:59.000Z

    Preformed phosphate, soft tissue pump and atmospheric CO 2 ,efficiency of the biological pump Tim DeVries, 1 Francoisproduces a “biological pump” that reduces the concentration

  4. Computational biology and high performance computing

    E-Print Network [OSTI]

    Shoichet, Brian

    2011-01-01T23:59:59.000Z

    Biology and High Performance Computing Manfred Zorn, TeresaBiology and High Performance Computing Presenters: Manfred99-Portland High performance computing has become one of the

  5. Synthetic biology and crop engineering

    Broader source: Energy.gov [DOE]

    Breakout Session 2: Frontiers and Horizons Session 2-A: Synthetic Biology and the Promise of Biofuels Jonathan Burbaum, Program Director, Department of Energy, Office of Science, ARPA–E

  6. AGRI-SCIENCE CHEMICAL BIOLOGY

    E-Print Network [OSTI]

    photosynthetic efficiency Improve chemical agronomic and agro-ecological control measures Modelling through translation of chemical biology tools and technologies Control weeds, disease and pests Minimise a platform to steer future research and policy directions. · Encourage external outreach to engage

  7. Chemistry Division Department of Biological

    E-Print Network [OSTI]

    Heller, Barbara

    1 Chemistry Division Department of Biological and Chemical Sciences, Illinois Institute-13 Chemistry Division invites nominations for Kilpatrick Fellowship for the academic year 2012's Chemistry Department from 1947­1960. Mary Kilpatrick was a chemistry faculty member from 1947

  8. Biological Science | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeIdleBiological Science Biological Science The protozoan

  9. Computational Design of Viscoelastic Gels with Tunable Mechanical Energy Dissipation

    E-Print Network [OSTI]

    Adityan, Aarthy Kannan

    2014-01-01T23:59:59.000Z

    The development of engineered materials that exhibit mechanical characteristics similar to biological tissues can enable testing the effect of ballistics and designing of protective equipment. The physical instability of ...

  10. BioConstructs : methods for bio-inspired and bio-fabricated design

    E-Print Network [OSTI]

    Zolotovsky, Katia

    2012-01-01T23:59:59.000Z

    This work presents experimentation with design and fabrication methods, using biological systems either indirectly (as a source of inspiration and information for design) or directly (as a material production for fabrication). ...

  11. AN INTEGRATED BIOLOGICAL CONTROL SYSTEM AT HANFORD

    SciTech Connect (OSTI)

    JOHNSON AR; CAUDILL JG; GIDDINGS RF; RODRIGUEZ JM; ROOS RC; WILDE JW

    2010-02-11T23:59:59.000Z

    In 1999 an integrated biological control system was instituted at the U.S. Department of Energy's Hanford Site. Successes and changes to the program needed to be communicated to a large and diverse mix of organizations and individuals. Efforts at communication are directed toward the following: Hanford Contractors (Liquid or Tank Waste, Solid Waste, Environmental Restoration, Science and Technology, Site Infrastructure), General Hanford Employees, and Hanford Advisory Board (Native American Tribes, Environmental Groups, Local Citizens, Washington State and Oregon State regulatory agencies). Communication was done through direct interface meetings, individual communication, where appropriate, and broadly sharing program reports. The objectives of the communication efforts was to have the program well coordinated with Hanford contractors, and to have the program understood well enough that all stakeholders would have confidence in the work performed by the program to reduce or elimated spread of radioactive contamination by biotic vectors. Communication of successes and changes to an integrated biological control system instituted in 1999 at the Department of Energy's Hanford Site have required regular interfaces with not only a diverse group of Hanford contractors (i.e., those responsible for liquid or tank waste, solid wastes, environmental restoration, science and technology, and site infrastructure), and general Hanford employees, but also with a consortium of designated stake holders organized as the Hanford Advisory Board (i.e., Native American tribes, various environmental groups, local citizens, Washington state and Oregon regulatory agencies, etc.). Direct interface meetings, individual communication where appropriate, and transparency of the biological control program were the methods and outcome of this effort.

  12. Computational Fluid Dynamics Framework for Turbine Biological Performance Assessment

    SciTech Connect (OSTI)

    Richmond, Marshall C.; Serkowski, John A.; Carlson, Thomas J.; Ebner, Laurie L.; Sick, Mirjam; Cada, G. F.

    2011-05-04T23:59:59.000Z

    In this paper, a method for turbine biological performance assessment is introduced to bridge the gap between field and laboratory studies on fish injury and turbine design. Using this method, a suite of biological performance indicators is computed based on simulated data from a computational fluid dynamics (CFD) model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. If the relationship between the dose of an injury mechanism and frequency of injury (dose-response) is known from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from various turbine designs, the engineer can identify the more-promising designs. Discussion here is focused on Kaplan-type turbines, although the method could be extended to other designs. Following the description of the general methodology, we will present sample risk assessment calculations based on CFD data from a model of the John Day Dam on the Columbia River in the USA.

  13. Acceptance Criteria Framework for Autonomous Biological Detectors

    SciTech Connect (OSTI)

    Dzenitis, J M

    2006-12-12T23:59:59.000Z

    The purpose of this study was to examine a set of user acceptance criteria for autonomous biological detection systems for application in high-traffic, public facilities. The test case for the acceptance criteria was the Autonomous Pathogen Detection System (APDS) operating in high-traffic facilities in New York City (NYC). However, the acceptance criteria were designed to be generally applicable to other biological detection systems in other locations. For such detection systems, ''users'' will include local authorities (e.g., facility operators, public health officials, and law enforcement personnel) and national authorities [including personnel from the Department of Homeland Security (DHS), the BioWatch Program, the Centers for Disease Control and Prevention (CDC), and the Federal Bureau of Investigation (FBI)]. The panel members brought expertise from a broad range of backgrounds to complete this picture. The goals of this document are: (1) To serve as informal guidance for users in considering the benefits and costs of these systems. (2) To serve as informal guidance for developers in understanding the needs of users. In follow-up work, this framework will be used to systematically document the APDS for appropriateness and readiness for use in NYC.

  14. Integrative Biology Keith A. Crandall, Chair

    E-Print Network [OSTI]

    Hart, Gus

    . The bioinformatics major is for students with interests in both the computer and the biological sciences. The degree merges these interests in the areas of bioinformatics and computational biology, giving students Programs and Degrees BS Bioinformatics BS Biology Composite Teaching BS Integrative Biology Students should

  15. Overview of selected molecular biological databases

    SciTech Connect (OSTI)

    Rayl, K.D.; Gaasterland, T.

    1994-11-01T23:59:59.000Z

    This paper presents an overview of the purpose, content, and design of a subset of the currently available biological databases, with an emphasis on protein databases. Databases included in this summary are 3D-ALI, Berlin RNA databank, Blocks, DSSP, EMBL Nucleotide Database, EMP, ENZYME, FSSP, GDB, GenBank, HSSP, LiMB, PDB, PIR, PKCDD, ProSite, and SWISS-PROT. The goal is to provide a starting point for researchers who wish to take advantage of the myriad available databases. Rather than providing a complete explanation of each database, we present its content and form by explaining the details of typical entries. Pointers to more complete ``user guides`` are included, along with general information on where to search for a new database.

  16. Request for Travel Funds for Systems Radiation Biology Workshop

    SciTech Connect (OSTI)

    Barcellos-Hoff, Mary Helen [NYU School of Medicine

    2014-03-22T23:59:59.000Z

    The 3rd International Systems Radiation Biology Workshop brought together the major European, US and Japanese research programs on radiation risk as well as selected experts representing systems biological approaches to discuss how the new methodologies could be best exploited for low dose research. A significant part of the workshop was devoted to discussions organised as breakout group sessions. To facilitate discussions number of participants was limited to 60 persons. To achieve the goals of this symposium in this international conference, support from DOE is vital. Hence, this proposal requested support in the amount of $15,000 to cover the travel expenses of international experts and radiation biology scientists from the United States. This supporting mechanism was clearly identified to the selected US participants as a conference support award from the DOE (See attached PDF). The workshop was an outstanding opportunity to strengthen interactions between leading experts in the emerging areas of radiation sciences, and will also provide opportunities for younger scientists to meet with experts and discuss their results. This workshop was designed to endorse active engagement in international collaboration. A major objective of this conference was to effectively communicate research results, in order to ensure that current thinking reflects sound science of radiation biology. Further, this international event addressed the use and success of scientific initiatives in radiation biology for policymakers, standard-setters, and the general public.

  17. Table 1. Connection of Criterion 8 CE Outcomes to CE Courses (required, design elective, advanced elective)

    E-Print Network [OSTI]

    Gelfond, Michael

    treatment Biological wastewater treatment (d) Proficiency in Water Resources Engineering CE 3305 CE 3354 CE systems Design of advance water treatment systems Design of biological wastewater treatment systems (g ENVE 4391 ENVE 4399 Water, wastewater, air, solid waste Physical and chemical treatment Advanced water

  18. Life in the Living Laboratory: An Anthropological Investigation of Environmental Science, Tourism, and Design in the Contemporary Bahamas

    E-Print Network [OSTI]

    Moore, Amelia M.

    2010-01-01T23:59:59.000Z

    envisioned through sustainable designs for living. It can bethe living laboratory- biological, sustainable, ecologicalsustainable economic development- processes of human life and living,

  19. Systems biology approach to bioremediation

    SciTech Connect (OSTI)

    Chakraborty, R.; Wu, C. H.; Hazen, T. C.

    2012-01-01T23:59:59.000Z

    Bioremediation has historically been approached as a ?black box? in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ?black box?.

  20. China's post-reform policy implementation gaps and governmental vs. non-governmental fire alarm solutions

    E-Print Network [OSTI]

    Hart, Melanie M.

    2010-01-01T23:59:59.000Z

    Journalism in Post- Deng China,” Journalism Studies, Vol. 1,Villagers and Popular Resistance in Contemporary China,”Modern China, Vol. 22, No. 1, pp. 28-61. O?Brien, Kevin J. (

  1. China's post-reform policy implementation gaps and governmental vs. non-governmental fire alarm solutions

    E-Print Network [OSTI]

    Hart, Melanie M.

    2010-01-01T23:59:59.000Z

    and Reform Committee EIA Environmental Impact Assessmentand Reforms,” Singapore East Asian Institute (EIA),EIA Background Brief No. 418, December 11, 2008, available

  2. China's post-reform policy implementation gaps and governmental vs. non-governmental fire alarm solutions

    E-Print Network [OSTI]

    Hart, Melanie M.

    2010-01-01T23:59:59.000Z

    Ibid. Walker (2008). planned hydropower projects in Yunnanlands are expropriated for hydropower developments. In 2004to lose their lands for a hydropower project on the Nujiang

  3. China's post-reform policy implementation gaps and governmental vs. non-governmental fire alarm solutions

    E-Print Network [OSTI]

    Hart, Melanie M.

    2010-01-01T23:59:59.000Z

    EIA) Office under the Metallurgy Ministry?s GeophysicsDepartment and asked the Metallurgy EIA office to conductnew factory. 771 The Metallurgy EIA office quickly completed

  4. China's post-reform policy implementation gaps and governmental vs. non-governmental fire alarm solutions

    E-Print Network [OSTI]

    Hart, Melanie M.

    2010-01-01T23:59:59.000Z

    an illegally-polluting smelter and the associated damage toGroup to build the smelter in their nascent industrial park.Even more importantly, the smelter would bring in a huge

  5. Chemical and Biological Engineering Department Code 1 Department of Chemical & Biological Engineering

    E-Print Network [OSTI]

    Chemical and Biological Engineering Department Code 1 CODE of the Department of Chemical of Chemical & Biological Engineering. For clarity of presentation, some passages are copied directly from shall offer an undergraduate chemical and biological engineering program of technological, scientific

  6. A bioinformatics/computational biology postdoctoral research position available to analyze biological networks in plants

    E-Print Network [OSTI]

    Lu, Jiaheng

    A bioinformatics/computational biology postdoctoral research position available to analyze biological networks in plants A bioinformatics postdoctoral position is available immediately in the laboratory of Dr. Sue Rhee at the Carnegie Institution, Department of Plant Biology (Stanford, CA

  7. Theoretical Physics in Cellular Biology

    E-Print Network [OSTI]

    Theoretical Physics in Cellular Biology: Some Illustrative Case Studies Living matter obeys the laws of physics, and the principles and methods of theoretical physics ought to find useful application observation, I will describe a few specific instances where approaches inspired by theoretical physics allow

  8. DEGREE REQUIREMENTS BIOLOGICAL ENGINEERING TECHNOLOGY

    E-Print Network [OSTI]

    Walter, M.Todd

    DEGREE REQUIREMENTS BIOLOGICAL ENGINEERING TECHNOLOGY ENVIRONMENTAL ENGINEERING TECHNOLOGY The curriculum in the technology programs must satisfy the College of Agriculture and Life Sciences (CALS for the technology programs are listed by subject matter in three major categories: (A) Basic Subjects, (B) Advanced

  9. WithCarbonSequestration Biological-

    E-Print Network [OSTI]

    · Techno-Economic Analysis of H2 Production by Gasification of Biomass · Renewables Analysis · BiomassWithCarbonSequestration Biomass Hydro Wind Solar Coal Nuclear Natural Gas Oil Biological- and Biomass- Based Hydrogen Production RoxanneRoxanne DanzDanz #12;Barriers Hydrogen Production from Biomass

  10. Biological Impacts of Climate Change

    E-Print Network [OSTI]

    McCarty, John P.

    Biological Impacts of Climate Change John P McCarty, University of Nebraska at Omaha, Omaha, NE and reproduction depend on how well adapted individuals are to local climate patterns. Climate change can disrupt subsequent impacts on populations or species' distributions across geographic regions. Climate change may

  11. Theory in Biology available light

    E-Print Network [OSTI]

    Nowak, Martin A.

    Magazine R406 Theory in Biology Theory is available light Martin A. Nowak Many people praise Gregor the neutral theory of evolution, which assumes that the overwhelming majority of molecular mutations do assume the neutral theory is correct. In a brilliant PhD thesis submitted in 1964, Bill Hamilton

  12. Department of Biology -Committees and Representatives

    E-Print Network [OSTI]

    Simons Biology Safety Committee Dave Omond Ed Bruggink Jim Cheetham (Chair) Mike Weber Biology Space Committee Jim Cheetham (Chair) Mike Weber Tom Sherratt Ed Bruggink Curriculum Committee (elected) Tom

  13. MS.BIOLOGY.THESIS ACADEMIC LEARNING PLAN

    E-Print Network [OSTI]

    O'Laughlin, Jay

    effectively to constructive feedback. Job Prospects for Biology Graduates MS in Biology Bioremediation Biotechnology Medical Research Industry Government Education Microbiology Health Professions Research Health Food Production Pollution Control Environmental Diagnostics Forestry Agriculture #12;APPENDIX B

  14. Stochastic processes in biological systems : selected problems

    E-Print Network [OSTI]

    Artomov, Maksym

    2010-01-01T23:59:59.000Z

    Majority of biological processes can not be described deterministically. Multple levels of regulation contribute to the noise in the observable properties of the cells: fluctuations are ubiquitous in biological networks ...

  15. Abiotic and Biological Transformation of Tetraalkoxysilanes

    E-Print Network [OSTI]

    Semprini, Lewis

    . An aerobic microbial culture from the local wastewater treatment plant that could grow and mineralizeAbiotic and Biological Transformation of Tetraalkoxysilanes and Trichloroethene/ cis-1 compounds (tetra- alkoxysilanes) by abiotic hydrolysis and biological mineralization was investigated

  16. Noah A. Rosenberg Department of Biology

    E-Print Network [OSTI]

    Rosenberg, Noah

    , Life Sciences Institute and Center for Computational Medicine & Bioinformatics, University of Michigan Education 2001-2005 University of Southern California, Postdoc, Molecular and Computational Biology 1998, BMC Bioinformatics 2010- Editorial Board Member, Human Biology 2010- Associate Editor, Genetics 2009

  17. Autonomous observations of the ocean biological carbon pump

    E-Print Network [OSTI]

    Bishop, James K.B.

    2009-01-01T23:59:59.000Z

    efficiency of biological pump in the global ocean. JournalOcean Biological Carbon Pump Carbon Flux Explorerocean’s “biological carbon pump” (Broecker and Peng, 1982;

  18. advanced molecular biology: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    311 Biology and Medicine Websites Summary: Molecular Biology Biology 311 Fall 2013 Syllabus Instructor: Dr. Deborah Lycan Class: MWF 9@lclark.edu Website: http:...

  19. PG&E Reconductoring Project Biological Assessment (Revised) ...

    Broader source: Energy.gov (indexed) [DOE]

    PG&E Reconductoring Project Biological Assessment (Revised) PG&E Reconductoring Project Biological Assessment (Revised) PG&E Reconductoring Project Biological Assessment (1216...

  20. EMSL Biological Interactions and Dynamics Science Theme Advisory...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Interactions and Dynamics Science Theme Advisory Panel Workshop EMSL Biological Interactions and Dynamics Science Theme Advisory Panel Workshop "Biological Interactions...

  1. Biological Inventory Colorado Canyons National Conservation Area

    E-Print Network [OSTI]

    Biological Inventory of the Colorado Canyons National Conservation Area Prepared by: Joe Stevens .............................. 12 Identify Targeted Inventory Areas

  2. A Biological Inventory and Conservation Recommendations

    E-Print Network [OSTI]

    A Biological Inventory and Conservation Recommendations for the Great Sand Dunes and San Luis Lakes General Services Building Ft. Collins, Colorado 80523 March 1999 i #12;A Biological Inventory PROGRAM SAGUACHE, COLORADO P.O. Box 674, Saguache, Colorado 81149 ii #12;Biological Inventory of the Great

  3. School of Environmental and Biological Sciences

    E-Print Network [OSTI]

    Goodman, Robert M.

    School of Environmental and Biological Sciences #12;Who We are and What We do Students at the Rutgers School of Environmental and Biological Sciences are part of a rich history of learning, innovation) Biological Sciences Biotechnology Animal Biotechnology Bioinformatics Bioscience Policy and Management

  4. Applications to Computational Molecular Biology Giuseppe Lancia

    E-Print Network [OSTI]

    Lancia, Giuseppe

    of the first type Bioinformatics problems, and reserve the term Computational Biology for the study of problemsApplications to Computational Molecular Biology Giuseppe Lancia 1 Introduction Computational decade. The seeds for the birth of Computational Biology were sowed in the end of the Seventies, when

  5. Undergraduate Minor in Computational biology & bioinformatics

    E-Print Network [OSTI]

    Logan, David

    Undergraduate Minor in Computational biology & bioinformatics Course Title Hours CSCE 155T Intro@unl.edu The Computational Biology and Bioinformatics (CBB) Minor is an interdisciplinary program that prepares students and for related graduate studies. The Computational Biology & Bioinformatics (CBB) Minor requires 13 credit hours

  6. Bioinformatics and Computational Biology Services Introduction

    E-Print Network [OSTI]

    Steiner, Ullrich

    Bioinformatics and Computational Biology Services Introduction Jenny Barna, Department of the Biological Sciences bioinformatics and computational biology research support service, which is used it provides. There are servers with many cores and very large memory (RAM) on which you can run computing jobs

  7. Designer Cosmology

    E-Print Network [OSTI]

    Bruce A. Bassett; David Parkinson; Robert C. Nichol

    2005-07-05T23:59:59.000Z

    We highlight the flexibility of the IPSO experiment-design framework by contrasting its application to CMB, weak lensing and redshift surveys. We illustrate the latter with a 10 parameter MCMC D-optimisation of a dark energy redshift survey. When averaged over a standard dark energy model space the resulting optimal survey typically has only one or two redshift bins, located at zoptimisation we show how the statistical power of such surveys is significantly enhanced. Experiment design is aided by the richness of the figure of merit landscape which means one can impose secondary optimisation criteria at little cost. For example, one may choose either to maximally test a single model (such as \\Lambda CDM) or to get the most general model-independent constraints possible (e.g. on a whole space of dark energy models). Such freedom points to a future where cosmological experiments become increasingly specialised and optimisation increasingly important.

  8. Roadmap: Biology Organismal Biology Bachelor of Science [AS-BS-BSCI-ORBI

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Biology ­ Organismal Biology ­ Bachelor of Science [AS-BS-BSCI-ORBI] College of Arts/LNHD This roadmap is a recommended semester-by-semester plan of study for this major. However, courses General Elective 3 #12;Roadmap: Biology ­ Organismal Biology ­ Bachelor of Science [AS

  9. ECOLOGY, EVOLUTION AND ENVIRONMENTAL BIOLOGY (for students entering Biology in Fall 2011 or later)

    E-Print Network [OSTI]

    Jiang, Wen

    ECOLOGY, EVOLUTION AND ENVIRONMENTAL BIOLOGY (for students entering Biology in Fall 2011 or later course other than BIOL 54200 124 Total Credits BIOLOGY: 1. BIOL 12100 Biology I: Diversity, Ecology 28600 Intro. to Ecology and Evolution (2 cr.; spring) or BIOL 29500, Intro. to Evolution & Ecology (2 cr

  10. BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 2014 Molecular Biology Building, Iowa State University, Ames, Iowa 50011-3260

    E-Print Network [OSTI]

    Mayfield, John

    BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 2014 Molecular Biology Building, Iowa State University of recommendation in my file at the Bioinformatics and Computational Biology program, Iowa State University. [ ] I in the Bioinformatics and Computational Biology program at Iowa State University. We would appreciate your evaluation

  11. Designing a Carbon Tax: The Introduction of the Carbon-Burned Tax (CBT)

    E-Print Network [OSTI]

    Cristian, Amy C.

    1992-01-01T23:59:59.000Z

    governmental subsidies, the fossil-fuel industries. The endsubsidy for a number of years, regardless of whether produ- cers reduced their actual fossil fuel

  12. Biological Engineering Electives Biosystems Engineering

    E-Print Network [OSTI]

    Hill, Jeffrey E.

    Control Theory (3) ECH 4323L Chemical Engineering Lab (1) ECH 4504 Chemical Kinetics & Reactor Design (4) ECH 4524 Heterogeneous Kinetics & Reactor Design (2) EGM 4313 Intermediate Engineering Analysis (4 Principles of Food Processing (4) FOS 4522C Seafood Technology (3) FOS 4722C Quality Control in Foods (3) FOS

  13. From the sea: Chemical and biological concerns. Final report

    SciTech Connect (OSTI)

    Murphy, J.M.

    1994-02-08T23:59:59.000Z

    With the collapse of the Soviet Union the U.S. Navy devised a new strategy, ... FROM THE SEA. This strategy is designed to prepare the Navy for regional challenges. Proliferation of weapons of mass destruction is a major concern of U.S. national defense. This paper uses some historical examples and technological data to postulate conceivable effects from chemical and biological weapons on FROM THE SEA. The focus of this paper is on the operational level of war. The paper addresses what the Navy and the Unified Commander in Chiefs should do to prepare for operations in a contaminated environment. Chemical warfare, Chemical defense, From the sea, Joint Operations, Joint Maritime Operations, Chemical weapons, Biological weapons.

  14. AGRICULTURAL AND BIOLOGICAL ENGINEERING PURSUE A GRADUATE DEGREE IN

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL AND BIOLOGICAL ENGINEERING PURSUE A GRADUATE DEGREE IN AGRICULTURAL AND BIOLOGICAL ENGINEERING Department of Agricultural and Biological Engineering 338 Agricultural Engineering Sciences of Agricultural and Biological Engineering offers a limited number of graduate fellowships and assistantships

  15. Ecology and Evolutionary Biology The Wiess School of Natural Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    Ecology and Evolutionary Biology The Wiess School of Natural Sciences Chair Evan Siemann Professors of Ecology and Evolutionary Biologyoffersabroadrangeofcoursesinthebiosciences:animalbehavior,animal biology, bioinformatics, conservation biology, diseases, ecology, evolutionary biology, field ecology, genetics, genomics

  16. Iosif Vaisman Department of Bioinformatics and Computational Biology

    E-Print Network [OSTI]

    Vaisman, Iosif

    Iosif Vaisman Department of Bioinformatics and Computational Biology Email: ivaisman@gmu.edu BINF agreed on the following definitions of bioinformatics and computational biology recognizing STRUCTURAL BIOLOGY COMPUTATIONAL MOLECULAR BIOLOGY BIOINFORMATICS GENOMICS STRUCTURAL GENOMICS PROTEOMICS

  17. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.: Davis, J.C.; Stanker, L.H.

    1993-05-11T23:59:59.000Z

    A method is disclosed of quantifying molecules in biological substances, comprising: selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere; preparing a long-lived radioisotope labeled reactive chemical specie; administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system; allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host; isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources; converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation; and measuring the radioisotope concentration in the material by means of direct isotopic counting.

  18. First Passage Problems in Biology

    E-Print Network [OSTI]

    Tom Chou; Maria R. D'Orsogna

    2014-08-20T23:59:59.000Z

    Applications of first passage times in stochastic processes arise across a wide range of length and time scales in biological settings. After an initial technical overview, we survey representative applications and their corresponding models. Within models that are effectively Markovian, we discuss canonical examples of first passage problems spanning applications to molecular dissociation and self-assembly, molecular search, transcription and translation, neuronal spiking, cellular mutation and disease, and organismic evolution and population dynamics. In this last application, a simple model for stem-cell ageing is presented and some results derived. Various approximation methods and the physical and mathematical subtleties that arise in the chosen applications are also discussed.

  19. Systems biology of Microbial Communities

    SciTech Connect (OSTI)

    Navid, A; Ghim, C; Fenley, A; Yoon, S; Lee, S; Almaas, E

    2008-04-11T23:59:59.000Z

    Microbes exist naturally in a wide range of environments, spanning the extremes of high acidity and high temperature to soil and the ocean, in communities where their interactions are significant. We present a practical discussion of three different approaches for modeling microbial communities: rate equations, individual-based modeling, and population dynamics. We illustrate the approaches with detailed examples. Each approach is best fit to different levels of system representation, and they have different needs for detailed biological input. Thus, this set of approaches is able to address the operation and function of microbial communities on a wide range of organizational levels.

  20. Biological Safety | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergyandapproximately 10 wt%inand FuelBiological

  1. Computational Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would like submit theInnovationComputational Biology SHARE Computational

  2. Systems Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposed Action(InsertAbout the GeothermalSystems Biology

  3. Green Biologics | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are8COaBulkTransmissionSitingProcess.pdfGetec AG Contracting JumpGoveNebraska:Ethanol LLC GO EthanolBiologics Jump to:

  4. Biological Applications of Synchrotron Radiation:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProduction PetraBiological

  5. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  6. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2006-01-24T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

  7. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  8. Electrostatic thin film chemical and biological sensor

    DOE Patents [OSTI]

    Prelas, Mark A. (Columbia, MO); Ghosh, Tushar K. (Columbia, MO); Tompson, Jr., Robert V. (Columbia, MO); Viswanath, Dabir (Columbia, MO); Loyalka, Sudarshan K. (Columbia, MO)

    2010-01-19T23:59:59.000Z

    A chemical and biological agent sensor includes an electrostatic thin film supported by a substrate. The film includes an electrostatic charged surface to attract predetermined biological and chemical agents of interest. A charge collector associated with said electrostatic thin film collects charge associated with surface defects in the electrostatic film induced by the predetermined biological and chemical agents of interest. A preferred sensing system includes a charge based deep level transient spectroscopy system to read out charges from the film and match responses to data sets regarding the agents of interest. A method for sensing biological and chemical agents includes providing a thin sensing film having a predetermined electrostatic charge. The film is exposed to an environment suspected of containing the biological and chemical agents. Quantum surface effects on the film are measured. Biological and/or chemical agents can be detected, identified and quantified based on the measured quantum surface effects.

  9. Functional quantum biology in photosynthesis and magnetoreception

    E-Print Network [OSTI]

    Lambert, Neill; Cheng, Yuan-Chung; Li, Che-Ming; Chen, Guang-Yin; Nori, Franco

    2012-01-01T23:59:59.000Z

    Is there a functional role for quantum mechanics or coherent quantum effects in biological processes? While this question is as old as quantum theory, only recently have measurements on biological systems on ultra-fast time-scales shed light on a possible answer. In this review we give an overview of the two main candidates for biological systems which may harness such functional quantum effects: photosynthesis and magnetoreception. We discuss some of the latest evidence both for and against room temperature quantum coherence, and consider whether there is truly a functional role for coherence in these biological mechanisms. Finally, we give a brief overview of some more speculative examples of functional quantum biology including the sense of smell, long-range quantum tunneling in proteins, biological photoreceptors, and the flow of ions across a cell membrane.

  10. Functional quantum biology in photosynthesis and magnetoreception

    E-Print Network [OSTI]

    Neill Lambert; Yueh-Nan Chen; Yuan-Chung Cheng; Che-Ming Li; Guang-Yin Chen; Franco Nori

    2012-05-04T23:59:59.000Z

    Is there a functional role for quantum mechanics or coherent quantum effects in biological processes? While this question is as old as quantum theory, only recently have measurements on biological systems on ultra-fast time-scales shed light on a possible answer. In this review we give an overview of the two main candidates for biological systems which may harness such functional quantum effects: photosynthesis and magnetoreception. We discuss some of the latest evidence both for and against room temperature quantum coherence, and consider whether there is truly a functional role for coherence in these biological mechanisms. Finally, we give a brief overview of some more speculative examples of functional quantum biology including the sense of smell, long-range quantum tunneling in proteins, biological photoreceptors, and the flow of ions across a cell membrane.

  11. On Biology as an Emergent Science

    E-Print Network [OSTI]

    H. Pierre Noyes

    2007-05-31T23:59:59.000Z

    Biology is considered here as an "emergent science" in the sense of Anderson and of Laughlin and Pines. It is demonstrated that a straightforward mathematical definition of "biological system" is useful in showing how biology differs in structure from the lower levels in Anderson's "More is Different" hierarchy. Using cells in a chemostat as a paradigmatic exemplar of a biological system, it is found that a coherent collection of metabolic pathways through a single cell in the chemostat also satisfies the proposed definition of a biological system. This provides a theoretical and mathematical underpinning for Young's fundamental model of biological organization and integration. Evidence for the therapeutic efficacy of Young's method of analysis is provided by preliminary results of clinical trials of a specific application of Young's model to the treatment of cancer cachexia.

  12. Biomedical Engineering AND Chemical & Biological Engineering Student Name:_________________________ Curriculum Check Sheet 158 Credits

    E-Print Network [OSTI]

    ; MATH 340) F 3 CBE 320 Chemical and Biological Reactor Design (CBE 201; CBE 330) S 3 BC 351 Principles BMS 300 Principles of Human Physiology (BZ 101 or 110 or LIFE 102; CHEM 103 or 107 or 111) F,S,SS 4

  13. BEE 260 Principles of Biological Engineering Assessment of Fall Semester 2006

    E-Print Network [OSTI]

    Walter, M.Todd

    BEE 260 Principles of Biological Engineering Assessment of Fall Semester 2006 1. Course Outcomes 1 reactor, composting, enzyme kinetics and their interactions with pesticides, food sterilization. The class surgery, food safety and nanobiotechnology (j). 5. Students were introduced to design principles (c). 2

  14. BEE 2600 Principles of Biological Engineering Assessment of Fall Semester 2008

    E-Print Network [OSTI]

    Walter, M.Todd

    BEE 2600 Principles of Biological Engineering Assessment of Fall Semester 2008 1. Course Outcomes 1 reactor, composting, enzyme kinetics and their interactions with pesticides, food sterilization. The class to design principles (c). 2. Assessment Methods/Metrics Homework problem sets were generated that had

  15. Biomedical Engineering AND Chemical & Biological Engineering Student Name:_________________________ Curriculum Check Sheet 158 Credits

    E-Print Network [OSTI]

    Process Simulation (CBE 210; MATH 340) F 3 CBE 320 Chemical and Biological Reactor Design (CBE 201; CBE 332 Heat and Mass Transfer Fundamentals (CBE 330; CBE 331) S 3 BMS 300 Principles of Human Physiology Principles of Biochem. (BZ 110 or 120 or LIFE 102; CHEM 245 or 341 or 345) F,S,SS 4 AUCC

  16. HANDLING ARABIDOPSIS PLANTS AND SEEDS Methods used by the Arabidopsis Biological Resource Center

    E-Print Network [OSTI]

    Meier, Iris

    . These procedures are designed to generate healthy plants that give maximum set of pure seeds and to preserveHANDLING ARABIDOPSIS PLANTS AND SEEDS Methods used by the Arabidopsis Biological Resource Center GROWTH OF PLANTS Growth of plants in sterile conditions Growth of plants on soil · Planting on soil

  17. Biology 534: Modern methods in Population Genomics 3 credits Spring 2015

    E-Print Network [OSTI]

    Collins, Gary S.

    #12;#12;#12;Biology 534: Modern methods in Population Genomics 3 credits Spring 2015 Instructor will be done by the instructor Catalog Description: Problems and prospects of designing a study with genomic revolutionized by the possibility of generating genomic sequence data. Interestingly, much of theoretical

  18. Thermodynamics for Systems Biology Peter Salamon, Anna Salamon, and Andrzej Konopka

    E-Print Network [OSTI]

    Salamon, Peter

    1 Thermodynamics for Systems Biology Peter Salamon, Anna Salamon, and Andrzej Konopka Department to thermodynamics designed specifically for the needs of the systems biologist. It departs from modern treatments of the subject that have to do with modeling, i.e. to communicate thermodynamics as a body of worldviews, methods

  19. Molecular biology of signal transduction in plants

    SciTech Connect (OSTI)

    Not Available

    1991-01-01T23:59:59.000Z

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  20. Innovative Breakthrough Demonstrated for Biological Ethanol Production...

    Office of Environmental Management (EM)

    for Biological Ethanol Production June 30, 2015 - 11:43am Addthis Advanced Biofuels Process Demonstration Unit at Lawrence Berkeley National Laboratory. Photo credit:...

  1. Carbonic Acid Shows Promise in Geology, Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Surprising Secrets of Carbonic Acid Probing the Surprising Secrets of Carbonic Acid Berkeley Lab Study Holds Implications for Geological and Biological Processes October 23,...

  2. Biological Survey of the Upper Purgatoire Watershed

    E-Print Network [OSTI]

    Biological Survey of the Upper Purgatoire Watershed Las Animas County, CO John Carney Colorado ...............................................................................................................9 Management Urgency Ranks ........................................................................................................10 POTENTIAL CONSERVATION SITE PLANNING BOUNDARIES........................................12 Off

  3. Design and study of a risk management criterion for an unstable anaerobic wastewater

    E-Print Network [OSTI]

    Bernard, Olivier

    Design and study of a risk management criterion for an unstable anaerobic wastewater treatment an unstable biological process used for wastewater treat- ment. This anaerobic digestion ecosystem can have digestion, Nonlinear systems diagnosis 1 Introduction and motivation Control of biological systems is a very

  4. EMSL - Biosystem Dynamics & Design

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    EMSL can improve strategies for modifying and manipulating plants, fungi and microbes to advance systems biology for bioenergy and biorenewables. Within this science theme, EMSL...

  5. Plant Species Biology (2003) 18, 123127 2003 The Society for the Study of Species Biology

    E-Print Network [OSTI]

    Tomimatsu,, Hiroshi

    2003-01-01T23:59:59.000Z

    and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, JapanPlant Species Biology (2003) 18, 123­127 © 2003 The Society for the Study of Species Biology Blackwell Science, LtdOxford, UKPSBPlant Species Biology1442-1984The Society for the Study of Species

  6. Department of Biological & Ecological Engineering

    E-Print Network [OSTI]

    Tullos, Desiree

    .3 Facility Design 5.4 Facility Testing and Maintenance 6.0 STANDARD AND SPECIAL OPERATING PROCEDURES 6.1 Standard Operating Procedures #12;6.2 Special Procedures 6.3 Respiratory Protection Program 6.4 Substance 1910.1450), "Occupational Exposures in Laboratories" referred to as the "Laboratory Standard". In order

  7. Computer-Aided Design for Microfluidic Chips Based on Multilayer Soft Lithography

    E-Print Network [OSTI]

    Amarasinghe, Saman P.

    Microfluidic chips are emerging as a powerful platform for automating biology experiments. As it becomes possible to integrate tens of thousands of components on a single chip, researchers will require design automation ...

  8. Computational models with thermodynamic and composition features improve siRNA design

    E-Print Network [OSTI]

    Shabalina, Svetlana A.

    Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large functional genomics projects. Results: To ...

  9. Biological Hydrogen Production Using a Membrane Bioreactor

    E-Print Network [OSTI]

    Biological Hydrogen Production Using a Membrane Bioreactor Sang-Eun Oh,1 Prabha Iyer,1,2 Mary Ann bioreactor (MBR) for biological hydrogen production. The reactor was fed glucose (10,000 mg/L) and inoculated were used. B 2004 Wiley Periodicals, Inc. Keywords: membrane bioreactor; hydrogen production

  10. Southeastern Colorado Survey of Critical Biological Resources

    E-Print Network [OSTI]

    Southeastern Colorado Survey of Critical Biological Resources 2007 #12;ii #12;Southeastern Colorado Survey of Critical Biological Resources Prepared for: Colorado Cattleman's Agricultural Land Trust 8833 Department of Natural Resources Division of State Board of Land Commissioners 1313 Sherman Street Denver, CO

  11. Ninth International Workshop on Plant Membrane Biology

    SciTech Connect (OSTI)

    Not Available

    1993-12-31T23:59:59.000Z

    This report is a compilation of abstracts from papers which were discussed at a workshop on plant membrane biology. Topics include: plasma membrane ATP-ases; plant-environment interactions, membrane receptors; signal transduction; ion channel physiology; biophysics and molecular biology; vaculor H+ pumps; sugar carriers; membrane transport; and cellular structure and function.

  12. Book Review Geothermal Biology and Geochemis-

    E-Print Network [OSTI]

    Book Review Geothermal Biology and Geochemis- try in Yellowstone National Park. (eds WP Inskeep of life. The legacy of chemical and biologi- cal research in geothermal regimes, while short in duration geothermal areas, including Yellowstone, are largely confined to the specialty literature of geochemical

  13. STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS

    E-Print Network [OSTI]

    STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted to the Office of Graduate Studies Head of Department, Valerie Taylor December 2005 Major Subject: Computer Science #12;iii ABSTRACT

  14. Bi23 BIOLOGY TUTORIALS WINTER TERM 2014

    E-Print Network [OSTI]

    Low, Steven H.

    Bi23 BIOLOGY TUTORIALS WINTER TERM 2014 SECTIONS 1 ­ 3 The Function and Regulation of Sleep (3. Huang, x3446, MC 156-29 #12;Bi23 BIOLOGY TUTORIALS WINTER TERM 2014 SECTIONS 4-6 Physical Principles crystallography and neutron scattering; nuclear magnetic resonance and magnetic resonance imaging; peptide and DNA

  15. Genome Biology 2005, 6:312 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Kellis, Manolis

    Genome Biology 2005, 6:312 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch Meeting report Large-scale discovery and validation of functional elements in the human genome-mail: bbernst@fas.harvard.edu. Manolis Kellis. E-mail: manoli@mit.edu Published: 1 March 2005 Genome Biology

  16. Genome Biology 2006, 7:320 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Pritham, Ellen J.

    Genome Biology 2006, 7:320 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch Meeting report Mobile DNA: genomes under the influence Cédric Feschotte and Ellen J Pritham Feschotte. Email: cedric@uta.edu Published: 30 June 2006 Genome Biology 2006, 7:320 (doi:10.1186/gb-2006

  17. FINAL REPORT FOR: OPTIMIZATION OF BIOLOGICAL

    E-Print Network [OSTI]

    AND SUSPENDED GROWTH WASTEWATER TREATMENT SYSTEM DECEMBER, 1994 Prepared for: Environment Canada Environment#12;FINAL REPORT FOR: OPTIMIZATION OF BIOLOGICAL PHOSPHORUS AND AMMONIA REMOVAL IN A COMBINED FIXED;Optimization of Biological Phosphorus and Ammonia Removal in a Combined Fixed & Suspended Growth System i

  18. Waste Handling and Disposal Biological Safety

    E-Print Network [OSTI]

    Pawlowski, Wojtek

    plumbing services, EHS personnel wastewater treatment plant personnel, and the general public canWaste Handling and Disposal Biological Safety General Biosafety Practices (GBP) Why You Should Care on the next experiment. Are you working with r/sNA, biological toxins, human materials, needles, plasticware

  19. Conceptual design summary

    SciTech Connect (OSTI)

    Peretz, F.J.

    1992-09-01T23:59:59.000Z

    The Advanced Neutron Source (ANS) is a new basic and applied research facility based on a powerful steady-state research reactor that provides beams of neutrons for measurements and experiments in the fields of materials science and engineering, biology, chemistry, materials analysis, and nuclear science. The useful neutron flux for these experiments will be at least five times, and in some cases twenty times, more than is available at the world`s best existing facilities. In addition, ANS will provide irradiation capabilities for the production of radioisotopes for medical applications, research, and industry and facilities for materials irradiation testing. The need for a new steady-state neutron research facility in the United States was emphasized by the 1984 National Academy Report and confirmed by the Department of Energy`s (DOE`s) Energy Research Advisory Board in 1985. These studies defined a minimum thermal neutron flux requirement of 5 {times} 10{sup 19} m{sup {minus}2} {center_dot} s{sup {minus}1}. The National Steering Committee for an Advanced Neutron Source, with representation from the major fields of science that will use the facility, was established in 1986 and has continued to define the performance requirements and instrument layouts needed by the user community. To minimize technical risks and safety issues, the project adopted a policy of not relying upon new inventions to meet the minimum performance criteria, and the design presented in this report is built on technologies already used in other facilities and development programs: for example, the involute aluminum-clad fuel plates common to HFIR and ILL and the uranium silicide fuel developed in DOE`s Reduced Enrichment for Research and Test Reactors program and tested in reactors worldwide. At the same time, every state-of-the-art technique has been implemented to optimize neutron beam delivery at the experiments.

  20. Conceptual design summary

    SciTech Connect (OSTI)

    Peretz, F.J.

    1992-09-01T23:59:59.000Z

    The Advanced Neutron Source (ANS) is a new basic and applied research facility based on a powerful steady-state research reactor that provides beams of neutrons for measurements and experiments in the fields of materials science and engineering, biology, chemistry, materials analysis, and nuclear science. The useful neutron flux for these experiments will be at least five times, and in some cases twenty times, more than is available at the world's best existing facilities. In addition, ANS will provide irradiation capabilities for the production of radioisotopes for medical applications, research, and industry and facilities for materials irradiation testing. The need for a new steady-state neutron research facility in the United States was emphasized by the 1984 National Academy Report and confirmed by the Department of Energy's (DOE's) Energy Research Advisory Board in 1985. These studies defined a minimum thermal neutron flux requirement of 5 {times} 10{sup 19} m{sup {minus}2} {center dot} s{sup {minus}1}. The National Steering Committee for an Advanced Neutron Source, with representation from the major fields of science that will use the facility, was established in 1986 and has continued to define the performance requirements and instrument layouts needed by the user community. To minimize technical risks and safety issues, the project adopted a policy of not relying upon new inventions to meet the minimum performance criteria, and the design presented in this report is built on technologies already used in other facilities and development programs: for example, the involute aluminum-clad fuel plates common to HFIR and ILL and the uranium silicide fuel developed in DOE's Reduced Enrichment for Research and Test Reactors program and tested in reactors worldwide. At the same time, every state-of-the-art technique has been implemented to optimize neutron beam delivery at the experiments.

  1. Aspects of the political economy of development and synthetic biology

    E-Print Network [OSTI]

    Wellhausen, Rachel

    What implications might synthetic biology’s potential as a wholly new method of production have for the world economy, particularly developing countries? Theories of political economy predict that synthetic biology can ...

  2. ASTRONOMY BIOLOGY CHEMISTRY COMPUTER-SCIENCE GEOGRAPHY MATHEMATICS PHYSICS STATISTICS

    E-Print Network [OSTI]

    Bernstein, Phil

    BIOMEDICAL-ENGINEERING ELECTRONIC- ENGINEERING ASTRONOMY BIOLOGY CHEMISTRY COMPUTER-SCIENCE GEOGRAPHY MATHEMATICS PHYSICS STATISTICS HEALTHCARE BIOMEDICAL-ENGINEERING ELECTRONIC-ENGINEERING ASTRONOMY BIOLOGY C H HEALTHCARE BIOMEDICAL-ENGINEERING ELECTRONIC-ENGINEERING ASTRONOMY BIOLOGY CHEMISTRY COMPUTER

  3. Crafting life : a sensory ethnography of fabricated biologies

    E-Print Network [OSTI]

    Roosth, Hannah Sophia

    2010-01-01T23:59:59.000Z

    This ethnography tracks a diverse set of practices I term "constructive biologies," by which I mean efforts in the post-genomic life sciences to understand how biology works by making new biological things. I examine five ...

  4. What rough beast? Synthetic Biology and the Future of Biosecurity

    E-Print Network [OSTI]

    Mohr, Scott C.

    Synthetic biology seeks to create modular biological parts that can be assembled into useful devices, allowing the modification of biological systems with greater reliability, at lower cost, with greater speed, and by a ...

  5. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.; Davis, J.C.

    1994-12-27T23:59:59.000Z

    Disclosed is a method of quantifying molecules in biological substances comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system, d. allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host, e. isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources, f. converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in the material by means of direct isotopic counting. 5 figures.

  6. THE AMERICAN BIOLOGY TEACHER SLIME MOLD 537 Few laboratory exercises are designed to teach biology students about barriers

    E-Print Network [OSTI]

    Ross, Shane

    water into the Great Lakes in the 1980s have caused extensive ecological and eco- nomic damage (Miller through ballast water, ships are advised to take measures to avoid transporting exotic species in ballast to the movement of aquatic organisms, but only if every ship always follows these vol- untary compliances

  7. Micro/nanofabricated environments for synthetic biology

    SciTech Connect (OSTI)

    Collier, Pat [ORNL; Simpson, Michael L [ORNL

    2011-01-01T23:59:59.000Z

    A better understanding of how confinement, crowding and reduced dimensionality modulate reactivity and reaction dynamics will aid in the rational and systematic discovery of functionality in complex biological systems. Artificial micro- and nanofabricated structures have helped elucidate the effects of nanoscale spatial confinement and segregation on biological behavior, particularly when integrated with microfluidics, through precise control in both space and time of diffusible signals and binding interactions. Examples of nanostructured interfaces for synthetic biology include the development of cell-like compartments for encapsulating biochemical reactions, nanostructured environments for fundamental studies of diffusion, molecular transport and biochemical reaction kinetics, and regulation of biomolecular interactions as functions of micro- and nanofabricated topological constraints.

  8. advanced biological treatment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Patrice Ct DALHOUSIE UNIVERSITY 12;BIOL 3020.03 Advanced Cell Biology Syllabus Page 2 Course description For a cell to function Adl, Sina 2 Biological Cybernetics...

  9. XPS Analysis of Nanostructured Materials and Biological Surfaces...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Analysis of Nanostructured Materials and Biological Surfaces. XPS Analysis of Nanostructured Materials and Biological Surfaces. Abstract: This paper examines the types of...

  10. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009)...

  11. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    E-Print Network [OSTI]

    Oldenburg, Curtis M.

    2008-01-01T23:59:59.000Z

    Enhancement of soil carbon sequestration by amendment withBiologically Enhanced Carbon Sequestration: Research Needson Biologically Enhanced Carbon Sequestration, October 29,

  12. BE.442 Molecular Structure of Biological Materials, Fall 2005

    E-Print Network [OSTI]

    Zhang, Shuguang, Dr.

    Basic molecular structural principles of biological materials. Molecular structures of various materials of biological origin, including collagen, silk, bone, protein adhesives, GFP, self-assembling peptides. Molecular ...

  13. A Systems Biology Approach to Infectious Disease Research: Innovating...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm. A Systems Biology Approach to Infectious Disease Research: Innovating the...

  14. Comparative systems biology across an evolutionary gradient within...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    systems biology across an evolutionary gradient within the Shewanella genus . Comparative systems biology across an evolutionary gradient within the Shewanella genus . Abstract: To...

  15. Biological and Chemical Approaches to Diseases

    E-Print Network [OSTI]

    Morimoto, Richard

    , chaperones, heat shock response, protein folding and misfolding, unfolded protein response Abstract Many that proteostasis is influenced both by an adjustable proteostasis network capacity and protein folding energetics INTRODUCTION . . . . . . . . . . . . . . . . . . 960 PROTEIN FOLDING IN VITRO . . . 961 BIOLOGICALLY ASSISTED

  16. VEHICLE OPERATING PROCEDURES DEPARTMENT OF BIOLOGICAL SCIENCE

    E-Print Network [OSTI]

    Ronquist, Fredrik

    VEHICLE OPERATING PROCEDURES DEPARTMENT OF BIOLOGICAL SCIENCE GENERAL INFORMATION Vehicles resposniblity and disciplinary action. Vehicles may be used by faculty or staff from other departments complete the vehicle usage agreement form certifying that they have a valid driver's license

  17. Technical Working Group on Biological Evidence Preservation

    E-Print Network [OSTI]

    Perkins, Richard A.

    of Forensic Science (AAFS) Annual Meeting Thursday, February 20, 2014 #12;The State of Biological Evidence Dennis Davenport, Senior Crime Scene Investigator, Commerce City PD Rock Harmon, Consultant, DNARock

  18. BIOMEDICAL ENGINEERING CHEMICAL AND BIOLOGICAL ENGINEERING

    E-Print Network [OSTI]

    Heller, Barbara

    BIOMEDICAL ENGINEERING CHEMICAL AND BIOLOGICAL ENGINEERING CIVIL, ARCHITECTURAL, AND ENVIRONMENTAL ENGINEERING ELECTRICAL AND COMPUTER ENGINEERING MECHANICAL, MATERIALS, AND AEROSPACE ENGINEERING COLLEGE OF ENGINEERING IIT ARMOUR #12;WHY ENGINEERINGAT IIT ARMOUR? Five Departments. One Distinctive Educational

  19. BIOLOGICAL & AGRICULTURAL ENGINEERING DEPARTMENT POSITION ANNOUNCEMENT

    E-Print Network [OSTI]

    BIOLOGICAL & AGRICULTURAL ENGINEERING DEPARTMENT POSITION ANNOUNCEMENT Position Title: Assistant/Associate Professor and Extension Specialist (Water/Wastewater Engineering) Appointment: 70% Texas A&M Agri) and other environmental issues of concern to rural communities, agricultural producers, agri

  20. The Biology of Some Kansas Eumenidae

    E-Print Network [OSTI]

    Isely, Dwight

    1913-01-01T23:59:59.000Z

    This paper is based on field observations and collections made by the author while connected with the Biological Survey of the University of Kansas, in Northwestern Kansas, during the summer of 1912. Specimens of fully ...

  1. Stochastic modeling of biological sequence evolution

    E-Print Network [OSTI]

    Xu, Keyuan

    2005-01-01T23:59:59.000Z

    Markov models of sequence evolution are a fundamental building block for making inferences in biological research. This thesis reviews several major techniques developed to estimate parameters of Markov models of sequence ...

  2. Biological applications of weal polyelectrolyte multilayers

    E-Print Network [OSTI]

    Berg, Michael C., Ph. D. Massachusetts Institute of Technology

    2005-01-01T23:59:59.000Z

    This thesis research focused on biological applications of ultra-thin weak polyelectrolyte multilayers with specific emphasis on cell patterning, drug delivery, and antibacterial coatings. All of these very different ...

  3. Genetics and molecular biology of breast cancer

    SciTech Connect (OSTI)

    King, M.C. [California Univ., Berkeley, CA (United States); Lippman, M. [Georgetown Univ. Medical Center, Washington, DC (United States)] [comps.

    1992-12-31T23:59:59.000Z

    This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

  4. Elizabeth R. Dumont Department of Biology

    E-Print Network [OSTI]

    Dumont, Elizabeth R.

    collection on the biology- engineering interface" (P.I.) Direct Costs: $670,425 (includes $7,500 REU, UMass Amherst. 2007 Plenary Speaker, 14th International Bat Research Congress, Merida, Mexico 2006

  5. Complexity and Systems Biology of Microbial Biofuels

    E-Print Network [OSTI]

    Rand, David

    Complexity and Systems Biology of Microbial Biofuels 20-24 June 2011 (All and issues Theme: Biofuel systems and issues (Chair: Nigel Burroughs) 13 (Bielefeld) Biofuels from algae- challenges for industrial levels

  6. TCD-IISc Symposium "Chemistry & Chemical Biology"

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    actinide chemistry, with a focus on coordination and organometallic uranium chemistry. Paula ColavitaTCD-IISc Symposium "Chemistry & Chemical Biology" Trinity College Clive Williams, Dean of Chemistry. Research areas include supramolecular organic and inorganic chemistry and medicinal chemistry

  7. Nanotechnology: emerging tools for biology and medicine

    E-Print Network [OSTI]

    Wong, Ian Y.

    Historically, biomedical research has been based on two paradigms. First, measurements of biological behaviors have been based on bulk assays that average over large populations. Second, these behaviors have then been ...

  8. Statistical methods to infer biological interactions

    E-Print Network [OSTI]

    Tucker, George Jay

    2014-01-01T23:59:59.000Z

    Biological systems are extremely complex, and our ability to experimentally measure interactions in these systems is limited by inherent noise. Technological advances have allowed us to collect unprecedented amounts of raw ...

  9. Size adjustable separation of biologically active molecules

    E-Print Network [OSTI]

    Gutierrez, Mauricio R. (Mauricio Roberto)

    2004-01-01T23:59:59.000Z

    Separation of biologically active molecules (BAM's) is a problem for the pharmaceutical and biotechnology industries. Current technologies addressing this problem require too many techniques, toxic additives, and time to ...

  10. Molecular Mechanism of Biological Proton Transport

    SciTech Connect (OSTI)

    Pomes, R.

    1998-09-01T23:59:59.000Z

    Proton transport across lipid membranes is a fundamental aspect of biological energy transduction (metabolism). This function is mediated by a Grotthuss mechanism involving proton hopping along hydrogen-bonded networks embedded in membrane-spanning proteins. Using molecular simulations, the authors have explored the structural, dynamic, and thermodynamic properties giving rise to long-range proton translocation in hydrogen-bonded networks involving water molecules, or water wires, which are emerging as ubiquitous H{sup +}-transport devices in biological systems.

  11. Frontiers of NMR in Molecular Biology

    SciTech Connect (OSTI)

    NONE

    1999-08-25T23:59:59.000Z

    NMR spectroscopy is expanding the horizons of structural biology by determining the structures and describing the dynamics of blobular proteins in aqueous solution, as well as other classes of proteins including membrane proteins and the polypeptides that form the aggregates diagnostic of prion and amyloid diseases. Significant results are also emerging on DNA and RNA oligomers and their complexes with proteins. This meeting focused attention on key structural questions emanating from molecular biology and how NMR spectroscopy can be used to answer them.

  12. Computation & design for nanophotonics

    E-Print Network [OSTI]

    Oskooi, Ardavan F

    2010-01-01T23:59:59.000Z

    The versatility of computational design as an alternative to design by nanofabrication has made computers a reliable design tool in nanophotonics. Given that almost any 2d pattern can be fabricated at infrared length scales, ...

  13. The OME Framework for genome-scale systems biology

    SciTech Connect (OSTI)

    Palsson, Bernhard O.; Ebrahim, Ali; Federowicz, Steve

    2014-12-19T23:59:59.000Z

    The life sciences are undergoing continuous and accelerating integration with computational and engineering sciences. The biology that many in the field have been trained on may be hardly recognizable in ten to twenty years. One of the major drivers for this transformation is the blistering pace of advancements in DNA sequencing and synthesis. These advances have resulted in unprecedented amounts of new data, information, and knowledge. Many software tools have been developed to deal with aspects of this transformation and each is sorely needed [1-3]. However, few of these tools have been forced to deal with the full complexity of genome-scale models along with high throughput genome- scale data. This particular situation represents a unique challenge, as it is simultaneously necessary to deal with the vast breadth of genome-scale models and the dizzying depth of high-throughput datasets. It has been observed time and again that as the pace of data generation continues to accelerate, the pace of analysis significantly lags behind [4]. It is also evident that, given the plethora of databases and software efforts [5-12], it is still a significant challenge to work with genome-scale metabolic models, let alone next-generation whole cell models [13-15]. We work at the forefront of model creation and systems scale data generation [16-18]. The OME Framework was borne out of a practical need to enable genome-scale modeling and data analysis under a unified framework to drive the next generation of genome-scale biological models. Here we present the OME Framework. It exists as a set of Python classes. However, we want to emphasize the importance of the underlying design as an addition to the discussions on specifications of a digital cell. A great deal of work and valuable progress has been made by a number of communities [13, 19-24] towards interchange formats and implementations designed to achieve similar goals. While many software tools exist for handling genome-scale metabolic models or for genome-scale data analysis, no implementations exist that explicitly handle data and models concurrently. The OME Framework structures data in a connected loop with models and the components those models are composed of. This results in the first full, practical implementation of a framework that can enable genome-scale design-build-test. Over the coming years many more software packages will be developed and tools will necessarily change. However, we hope that the underlying designs shared here can help to inform the design of future software.

  14. 2010 Tetrapyrroles, Chemistry & Biology of Gordon Research Conference

    SciTech Connect (OSTI)

    Angela Wilks

    2010-07-30T23:59:59.000Z

    The objective of the Chemistry & Biology of Tetrapyrroles Gordon Conference is to bring together researchers from diverse disciplines that otherwise would not interact. By bringing biologists, chemists, engineers and clinicians with a common interest in tetrapyrroles the conference provides a forum for cross-disciplinary ideas and collaboration. The perspective provided by biologists, chemists, and clinicians working in fields such as newly discovered defects in human porphyrin metabolism, the myriad of strategies for light harvesting in photosynthetic organisms, novel tetrapyrroles that serve as auxiliary chromophores or enzyme cofactors, synthetic strategies in the design of novel tetrapyrrole scaffolds, and tetrapyrrole based cell signaling and regulatory systems, makes this conference unique in the field. Over the years the growing evidence for the role of tetrapyrroles and their reactive intermediates in cell signaling and regulation has been of increasing importance at this conference. The 2010 conference on Chemistry & Biology of Tetrapyrroles will focus on many of these new frontiers as outlined in the preliminary program listed. Speakers will emphasize unpublished results and new findings in the field. The oral sessions will be followed by the highly interactive afternoon poster sessions. The poster sessions provide all conferees with the opportunity to present their latest research and to exchange ideas in a more informal setting. As in the past, this opportunity will continue during the nightly social gathering that takes place in the poster hall following the evening lectures. All conferees are encouraged to submit and present posters. At the conference the best poster in the areas of biology, chemistry and medicine will be selected by a panel of previous conference chairs.

  15. A Standard Parts List for Biological Circuitry

    E-Print Network [OSTI]

    Arkin, Adam P

    1999-10-07T23:59:59.000Z

    One of the hallmarks of biochemical circuits found in nature is analog, asymmetric, asynchronous design. That

  16. Solar Design Workbook

    SciTech Connect (OSTI)

    Franta, G.; Baylin, F.; Crowther, R.; Dubin, F.; Grace, A., Griffith, J.W.; Holtz, M.; Kutscher, C.; Nordham, D.; Selkowitz, S.; Villecco, M.

    1981-06-01T23:59:59.000Z

    This Solar Design Workbook presents solar building design applications for commercial buildir^s. The book is divided into four sections. The first section describes the variety of solar applications in buildings including conservation aspects, solar fundamentals, passive systems, active systems, daylighting, and other solar options. Solar system design evaluation techniques including considerations for building energy requirements, passive systems, active systems, and economics are presented in Section II. The third section attempts to assist the designer in the building design process for energy conservation and solar applications including options and considerations for pre-design, design, and post-design phases. The information required for the solar design proee^ has not been fully developed at this time. Therefore, Section III is incomplete, but an overview of the considerations with some of the design proces elements is presented. Section IV illustrates ease studies that utilize solar applications in the building design.

  17. APPLICATION FOR STEVENS SCHOLARSHIP Department of Biological Sciences

    E-Print Network [OSTI]

    Rock, Chris

    :_____ Total Credit Hours Completed: __________ Transferred Credit Hours: __________ Biology Quality Points University Course Prefix Course Number Semester Letter Grade Grade Points Biology Quality Points e.g. BIOL 1403 A 4 16 Summed Biology Quality Points: *Biology courses include all with the prefixes: BIOL, BOT

  18. Agricultural & Biological Engineering Alumni Newsletter. Winter 2009 ABE@Illinois

    E-Print Network [OSTI]

    Gilbert, Matthew

    Agricultural & Biological Engineering Alumni Newsletter. Winter 2009 ABE@Illinois WINTER2009 Triple Crown for Illinois's Agricultural and Biological Engineering Program The Agricultural and Biological of Agricultural and Biological Engineering held its first annual "Celebrate ABE@Illinois" on September 5th and 6th

  19. MONOTONE INPUT/OUTPUT SYSTEMS, AND APPLICATIONS TO BIOLOGICAL SYSTEMS

    E-Print Network [OSTI]

    Enciso, Germán

    . iii #12;Preface: From Tycho Brahe To Microarrays How does mathematics fit into modern biology research

  20. 7.012 Introduction to Biology, Fall 2001

    E-Print Network [OSTI]

    Weinberg, Robert A. (Robert Allan), 1942-

    Cell biology, immunology, neurobiology, and an exploration into current research in cancer, genomics, and molecular medicine.

  1. Biological Conversion of Sugars to Hydrocarbons Technology Pathway

    SciTech Connect (OSTI)

    Davis, Ryan; Biddy, Mary J.; Tan, Eric; Tao, Ling; Jones, Susanne B.

    2013-03-31T23:59:59.000Z

    In support of the Bioenergy Technologies Office, the National Renewable Energy Laboratory (NREL) and the Pacific Northwest National Laboratory (PNNL) are undertaking studies of biomass conversion technologies to identify barriers and target research toward reducing conversion costs. Process designs and preliminary economic estimates for each of these pathway cases were developed using rigorous modeling tools (Aspen Plus and Chemcad). These analyses incorporated the best information available at the time of development, including data from recent pilot and bench-scale demonstrations, collaborative industrial and academic partners, and published literature and patents. This technology pathway case investigates the biological conversion of biomass derived sugars to hydrocarbon biofuels, utilizing data from recent literature references and information consistent with recent pilot scale demonstrations at NREL. Technical barriers and key research needs have been identified that should be pursued for the pathway to become competitive with petroleum-derived gasoline, diesel and jet range hydrocarbon blendstocks.

  2. Landauer in the age of synthetic biology: energy consumption and information processing in biochemical networks

    E-Print Network [OSTI]

    Mehta, Pankaj; Schwab, David J

    2015-01-01T23:59:59.000Z

    A central goal of synthetic biology is to design sophisticated synthetic cellular circuits that can perform complex computations and information processing tasks in response to specific inputs. The tremendous advances in our ability to understand and manipulate cellular information processing networks raises several fundamental physics questions: How do the molecular components of cellular circuits exploit energy consumption to improve information processing? Can one utilize ideas from thermodynamics to improve the design of synthetic cellular circuits and modules? Here, we summarize recent theoretical work addressing these questions. Energy consumption in cellular circuits serves five basic purposes: (1) increasing specificity, (2) manipulating dynamics, (3) reducing variability, (4) amplifying signal, and (5) erasing memory. We demonstrate these ideas using several simple examples and discuss the implications of these theoretical ideas for the emerging field of synthetic biology. We conclude by discussing h...

  3. DOE handbook: Design considerations

    SciTech Connect (OSTI)

    NONE

    1999-04-01T23:59:59.000Z

    The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline.

  4. BIOLOGY INTERNATIONAL The Official Journal of the International Union of Biological Sciences

    E-Print Network [OSTI]

    Slik, Ferry

    , RMIT University School of Civil, Environmental and Chemical Engineering, Building 10, level 12, 376 of Environmental Biology University of Guelph, Guelph, ON N3C 2B7, Canada e-mail: pkevan@uoguelph.ca Nicholas 1TN, UK e-mail: nmt1@cam.ac.uk Ralf Reski, Head, Plant Biotechnology, Faculty of Biology, University

  5. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark E. coli pangenomics - or - How to compare hundreds of E. coli genomes Fuzzy Dave Ussery Ullevål Universitetssykehus Oslo, Norway Wednesday, 10 December, 2008 #12;Comparative Microbial Genomics group Centerfor

  6. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology,TechnicalUniversityofDenmark Burkholderia Pan-genomics Dave Ussery Max Planck Institut fur Terrestrial Microbiology Marburg, Germany 26 May, 2008 - or - What can we learn from more than 50 sequenced genomes? #12;Comparative Microbial Genomics

  7. The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position

    E-Print Network [OSTI]

    The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position We in citizen science projects.The post-doc will join the extended CRI lab that includes synthetic and systems-sourcing, DIY approaches and gamification as part of a new European- funded project, Citizen CyberLab - a three

  8. An Innovative Strategy for Dual Inhibitor Design and Its Application in Dual Inhibition of Human Thymidylate

    E-Print Network [OSTI]

    Lee, Keun Woo

    An Innovative Strategy for Dual Inhibitor Design and Its Application in Dual Inhibition of Human (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute to other dual target drug designs. Citation: Arooj M, Sakkiah S, Cao Gp, Lee KW (2013) An Innovative

  9. A novel biomimetic approach to the design of high-performance

    E-Print Network [OSTI]

    Ritchie, Robert

    , ceramic­metal composites are ideal candi- dates. In particular, ceramic-matrix composites (CMCsA novel biomimetic approach to the design of high-performance ceramic­metal composites Maximilien E of extending natural biological design to develop new synthetic ceramic­ metal composite materials is examined

  10. Annu. Rev. Med. 2002. 53:595614 RATIONAL APPROACH TO AIDS DRUG DESIGN

    E-Print Network [OSTI]

    Annu. Rev. Med. 2002. 53:595­614 RATIONAL APPROACH TO AIDS DRUG DESIGN THROUGH STRUCTURAL BIOLOGY than a dozen drugs in the past 15 years for the treatment of AIDS offer an excellent example of progress in the field of rational drug design. At this time, the principal targets are reverse

  11. Quantum metrology and its application in biology

    E-Print Network [OSTI]

    Michael A. Taylor; Warwick P. Bowen

    2014-09-03T23:59:59.000Z

    Quantum metrology provides a route to overcome practical limits in sensing devices. It holds particular relevance in biology, where sensitivity and resolution constraints restrict applications both in fundamental biophysics and in medicine. Here, we review quantum metrology from this biological context. The understanding of quantum mechanics developed over the past century has already enabled important applications in biology, including positron emission tomography (PET) with entangled photons, magnetic resonance imaging (MRI) using nuclear magnetic resonance, and bio-magnetic imaging with superconducting quantum interference devices (SQUIDs). With the birth of quantum information science came the realization that an even greater range of applications arise from the ability to not just understand, but to engineer coherence and correlations in systems at the quantum level. In quantum metrology, quantum coherence and quantum correlations are engineered to enable new approaches to sensing. This review focusses specifically on optical quantum metrology, where states of light that exhibit non-classical photon correlations are used to overcome practical and fundamental constraints, such as the shot-noise and diffraction limits. Recent experiments have demonstrated quantum enhanced sensing of biological systems, and established the potential for quantum metrology in biophysical research. These experiments have achieved capabilities that may be of significant practical benefit, including enhanced sensitivity and resolution, immunity to imaging artifacts, and characterisation of the biological response to light at the single-photon level. New quantum measurement techniques offer even greater promise, raising the prospect for improved multi-photon microscopy and magnetic imaging, among many other possible applications.

  12. Computational Biology and High Performance Computing 2000

    SciTech Connect (OSTI)

    Simon, Horst D.; Zorn, Manfred D.; Spengler, Sylvia J.; Shoichet, Brian K.; Stewart, Craig; Dubchak, Inna L.; Arkin, Adam P.

    2000-10-19T23:59:59.000Z

    The pace of extraordinary advances in molecular biology has accelerated in the past decade due in large part to discoveries coming from genome projects on human and model organisms. The advances in the genome project so far, happening well ahead of schedule and under budget, have exceeded any dreams by its protagonists, let alone formal expectations. Biologists expect the next phase of the genome project to be even more startling in terms of dramatic breakthroughs in our understanding of human biology, the biology of health and of disease. Only today can biologists begin to envision the necessary experimental, computational and theoretical steps necessary to exploit genome sequence information for its medical impact, its contribution to biotechnology and economic competitiveness, and its ultimate contribution to environmental quality. High performance computing has become one of the critical enabling technologies, which will help to translate this vision of future advances in biology into reality. Biologists are increasingly becoming aware of the potential of high performance computing. The goal of this tutorial is to introduce the exciting new developments in computational biology and genomics to the high performance computing community.

  13. Biomedical Engineering AND Chemical & Biological Engineering Student Name:_________________________ Curriculum Check Sheet

    E-Print Network [OSTI]

    .; PH 141) F,S 5 TOTAL 17 TOTAL 17 3rd Year Fall 3rd Year Spring BC 351 Principles of Biochem. (BZ 110 or 120 or LIFE 102; CHEM 245 or 341 or 345) F,S,SS 4 BMS 300 Principles of Human Physiology (BZ 101; MATH 340) F 3 CBE 320 Chemical and Biological Reactor Design (CBE 310; CBE 330) S 3 CBE 330 Process

  14. Locomotive design and construction /

    E-Print Network [OSTI]

    Maris, James Clyde.

    1919-01-01T23:59:59.000Z

    gear design, Stephenson valve gear design, errors in link motion, setting Y/alschaert valve gear, setting Stephenson valve gear. Locomotive Cylinders 94 Design and Manufacture. Pistons and Piston Rods 98 Crossheads 103 Locomotive Guide Bars 107... Driving Boxes 109 Locomotive Frames 113 Connecting and Side Rods 115 Crank Pins and Axles 119 Throttles, Dry Pipes, and Steam Passages 121 Reversing Links 124 Jig Design for Locomotive Parts 127 Forge Block Design for Forging Locomotive Parts 130...

  15. Control system design guide

    SciTech Connect (OSTI)

    Sellers, David; Friedman, Hannah; Haasl, Tudi; Bourassa, Norman; Piette, Mary Ann

    2003-05-01T23:59:59.000Z

    The ''Control System Design Guide'' (Design Guide) provides methods and recommendations for the control system design process and control point selection and installation. Control systems are often the most problematic system in a building. A good design process that takes into account maintenance, operation, and commissioning can lead to a smoothly operating and efficient building. To this end, the Design Guide provides a toolbox of templates for improving control system design and specification. HVAC designers are the primary audience for the Design Guide. The control design process it presents will help produce well-designed control systems that achieve efficient and robust operation. The spreadsheet examples for control valve schedules, damper schedules, and points lists can streamline the use of the control system design concepts set forth in the Design Guide by providing convenient starting points from which designers can build. Although each reader brings their own unique questions to the text, the Design Guide contains information that designers, commissioning providers, operators, and owners will find useful.

  16. RNA : algorithms, evolution and design

    E-Print Network [OSTI]

    Schnall-Levin, Michael (Michael Benjamin)

    2011-01-01T23:59:59.000Z

    Modern biology is being remade by a dizzying array of new technologies, a deluge of data, and an increasingly strong reliance on computation to guide and interpret experiments. In two areas of biology, computational methods ...

  17. Designing Asynchronous Microprocessors Design Process Overview

    E-Print Network [OSTI]

    Martin, Alain

    ) Parallel CHP Parallel CHP Sequential CHP informal translation ISA process decomposition process decomposition compilation #15; Design process is a sequence of provably correct transformations. #15; First CHP the CHP decomposition. #15; The design style tends to em- phasize concurrency issues. 2 #12; Sequential

  18. ERISII Initial Design Document I . Design Goals

    E-Print Network [OSTI]

    Wiederhold, Gio

    ERISII Initial Design Document I . Design Goals The goals behind the ERISII system are to present the directions of I*3 technology in general. In the first half of this document, we will examine the particular thee primary prototype will be used by environmental restoration managers, while being flexible enough

  19. Development of a device for the measurement of biological tissue optical properties using the single Monte Carlo method

    E-Print Network [OSTI]

    Bendele, Travis Henry

    2013-02-22T23:59:59.000Z

    A honeycomb probe was designed to measure the optical properties of biological tissues using single Monte Carlo method. The ongoing project is intended to be a multi-wavelength, real time, and in-vivo technique to detect breast cancer. Preliminary...

  20. Department of Environmental Conservation, University of Massachusetts-Amherst Concentration in Wildlife, Fish and Conservation Biology 1

    E-Print Network [OSTI]

    Schweik, Charles M.

    Department of Environmental Conservation, University of Massachusetts-Amherst Concentration in Wildlife, Fish and Conservation Biology 1 Environmental Conservation Graduate Program Wildlife, Fish of Science (MS) and Doctor of Philosophy (PhD) degrees in Environmental Conservation (ECo) and is designed

  1. A Rational Approach to Governmental Decision Concerning Air Pollution

    E-Print Network [OSTI]

    Ellis, Howard M.

    This paper addresses a problem common to many government agencies--trying to specify a regulatory policy that is in some sense best for a given situation. Such questions demand the consideration of multiple conflicting ...

  2. ICES CM 2008/O:05 Theme Session: Governmental

    E-Print Network [OSTI]

    Charles, Anthony

    's University Halifax, Nova Scotia, Canada B3H3C3 Tel: 1-902-420-5732 tony.charles@smu.ca Not to be cited

  3. STATE GOVERNMENTAL RELATIONS 2013 SESSION UPDATE February 27, 2013

    E-Print Network [OSTI]

    Acton, Scott

    to the Health System, increasing by $5 million in FY2014 o Establishes the Medicaid Innovation and Reform-planning for Gilmer Hall and the Chemistry Building renovations o Corrects error in indigent care funding Commission to review, recommend, and approve innovation and reform proposals affecting the Virginia Medicaid

  4. Model Agreement Between Governmental Entity [State or Local Government...

    Broader source: Energy.gov (indexed) [DOE]

    More Documents & Publications Microsoft Word - DOE Template Financial Institution RFP.doc Energy Efficiency Loan Program Agreement Template Energy Efficiency Loan Program...

  5. Microsoft Word - GC Guidance on Inherently Governmental Functions...

    Office of Environmental Management (EM)

    from the three principal sources of Federal law: the Federal Activities Inventory Reform (FAIR) Act, 1 the Federal Acquisition Regulations (FAR), 2 and Office of Management...

  6. The Governmentalization of “Lifestyle” and the Biopolitics of Carbon

    E-Print Network [OSTI]

    Lipschutz, Ronnie D.

    2009-01-01T23:59:59.000Z

    Tim Jackson, “The Carbon Footprint of UK Households 1990-tried to quantify the carbon footprints (or similar metrics)

  7. Before the Senate Homeland Security and Governmental Affairs...

    Broader source: Energy.gov (indexed) [DOE]

    Kidd, Program Manager Federal Energy Management Program, Office of Energy Efficiency and Renewable Energy Subject: Cutting the Federal Government's Energy Bill: An Examination of...

  8. General Counsel's Office Issues Guidance on Inherently Governmental...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Creation of New Health, Safety and Security Office Westinghouse Pays 50,000 Civil Penalty to Resolve Light Bulb Efficiency Violations DOE Launches New Smart Grid Web Portal...

  9. Before the Senate Homeland Security and Governmental Affairs Subcommittee

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergy Christopher Smith, PrincipalEnergyon Contracting

  10. Before the Senate Homeland Security and Governmental Affairs Subcommittee

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergy Christopher Smith, PrincipalEnergyon

  11. Before the Senate Homeland Security and Governmental Affairs Subcommittee

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergy Christopher Smith, PrincipalEnergyonon Oversight

  12. Before the Senate Homeland Security and Governmental Affairs Subcommittee

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33Frequently20,000 RussianBy:WhetherNovember 13, 2009OakDepartment of Energy Energy and

  13. COGR Council on Governmental Relations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the YouTube platformBuilding Removal OngoingCERCLA SitesCHICAGOof Energy CNG in

  14. General Counsel's Office Issues Guidance on Inherently Governmental

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport inEnergy0.pdfTechnologiesNATIONAL003 IntellectualSECCSDepartment ofFunctions |

  15. Guidance on Inherently Governmental Functions | Department of Energy

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic2 OPAM Flash2011-12 OPAMGeneral GuidanceEnergyServices »

  16. 2002 DOE Final Inherently Governmental and Commercial Activities Inventory

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed off Energy.gov. Are you sureReportsofDepartmentSeriesDepartmentSmallRulemakingsElectricity Supply ||

  17. 2015 Inherently Governmental and Commercial Activity (IGCA) Inventory

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed off Energy.gov. Are you0 ARRA Newsletters 2010 ARRA Newsletters201416-17, 2015 | Department

  18. 2002 DOE Final Inherently Governmental and Commercial Activities Inventory

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The Future of BadTHE U.S. DEPARTMENT OFDecember 18,United States Department of2

  19. Guidance on Inherently Governmental Functions | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreaking of Blythe Solar Power Project Ground BreakingWater EfficiencyExGuidance on

  20. Association for Governmental Leasing & Finance (AGLF) | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureComments from Tarasa U.S.LLCEnergy AssistantServices Subcommittee

  1. Before Senate Committee on Homeland Security and Governmental Affairs

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S. Department ofJune 2, 2015 TheB2 March 5,Commerce |

  2. Before the Senate Homeland Security and Governmental Affairs Subcommittee

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S. Department ofJune 2, 2015Energyon Federal Financial Management, Government

  3. Model Agreement Between Governmental Entity [State or Local Government] and

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy ChinaofSchaeferApril 1,(EAC)TABLE OF CONTENTSTogetherThe high service|Financial

  4. Category:Non-governmental Organizations | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty EditCalifornia:Power LPInformationCashtonGo Back toFL" TheThese

  5. The acquisition of dangerous biological materials :

    SciTech Connect (OSTI)

    Aceto, Donato Gonzalo; Astuto-Gribble, Lisa M.; Gaudioso, Jennifer M.

    2007-11-01T23:59:59.000Z

    Numerous terrorist organizations have openly expressed interest in producing and deploying biological weapons. However, a limiting factor for many terrorists has been the acquisition of dangerous biological agents, as evidenced by the very few successful instances of biological weapons use compared to the number of documented hoaxes. Biological agents vary greatly in their ability to cause loss of life and economic damage. Some agents, if released properly, can kill many people and cause an extensive number of secondary infections; other agents will sicken only a small number of people for a short period of time. Consequently, several biological agents can potentially be used to perpetrate a bioterrorism attack but few are likely capable of causing a high consequence event. It is crucial, from a US national security perspective, to more deeply understand the likelihood that terrorist organizations can acquire the range of these agents. Few studies have attempted to comprehensively compile the technical information directly relevant to the acquisition of dangerous bacteria, viruses and toxins. In this report, technical fact sheets were assembled for 46 potentially dangerous biological agents. Much of the information was taken from various research sources which could ultimately and significantly expedite and improve bioterrorism threat assessments. By systematically examining a number of specific agent characteristics included in these fact sheets, it may be possible to detect, target, and implement measures to thwart future terrorist acquisition attempts. In addition, the information in these fact sheets may be used as a tool to help laboratories gain a rudimentary understanding of how attractive a method laboratory theft is relative to other potential acquisition modes.

  6. A BASIC GUIDE TO CHEMICAL & BIOLOGICAL ENGINEERING AT UA Much of the information included in this handout can be found at che.eng.ua.edu click on undergraduate

    E-Print Network [OSTI]

    Carver, Jeffrey C.

    151 Fundamental Engineering Graphics 1 __ 15 Second Semester BSC 114 Principles of Biology I (N) 3 CH Chemical Engineering Laboratory 2 CHE 354 Chemical Reactor Design 3 CH 237 Organic Chemistry Laboratory I 2 Calculus I (MA) 4 __ 15 Second Semester BSC 114 Principles of Biology I (N) 3 CH 102 General Chemistry II

  7. A BASIC GUIDE TO CHEMICAL & BIOLOGICAL ENGINEERING AT UA Much of the information included in this handout can be found at che.eng.ua.edu click on undergraduate

    E-Print Network [OSTI]

    Carver, Jeffrey C.

    151 Fundamental Engineering Graphics 1 __ 15 Second Semester BSC 114 Principles of Biology I (N) 3 CH Chemical Engineering Laboratory 2 CHE 354 Chemical Reactor Design 3 CH 237 Organic Chemistry Laboratory I 2 Composition I (FC) 3 MATH 125 Calculus I (MA) 4 __ 15 Second Semester BSC 114 Principles of Biology I (N) 3 CH

  8. Spectroscopic diagnostics for bacteria in biologic sample

    DOE Patents [OSTI]

    El-Sayed, Mostafa A. (Atlanta, GA); El-Sayed, Ivan H. (Somerville, MA)

    2002-01-01T23:59:59.000Z

    A method to analyze and diagnose specific bacteria in a biologic sample using spectroscopy is disclosed. The method includes obtaining the spectra of a biologic sample of a non-infected patient for use as a reference, subtracting the reference from the spectra of an infected sample, and comparing the fingerprint regions of the resulting differential spectrum with reference spectra of bacteria in saline. Using this diagnostic technique, specific bacteria can be identified sooner and without culturing, bacteria-specific antibiotics can be prescribed sooner, resulting in decreased likelihood of antibiotic resistance and an overall reduction of medical costs.

  9. Biology and Medicine Division: Annual report 1986

    SciTech Connect (OSTI)

    Not Available

    1987-04-01T23:59:59.000Z

    The Biology and Medicine Division continues to make important contributions in scientific areas in which it has a long-established leadership role. For 50 years the Division has pioneered in the application of radioisotopes and charged particles to biology and medicine. There is a growing emphasis on cellular and molecular applications in the work of all the Division's research groups. The powerful tools of genetic engineering, the use of recombinant products, the analytical application of DNA probes, and the use of restriction fragment length polymorphic DNA are described and proposed for increasing use in the future.

  10. Biological doses with template distribution patterns

    SciTech Connect (OSTI)

    Harrop, R. (Simon Fraer Univ., Burnaby, British Columbia); Haymond, H.R.; Nisar, A.; Syed, A.N.M.; Feder, B.H.; Neblett, D.L.

    1981-02-01T23:59:59.000Z

    Consideration of radiation dose rate effects emphasizes advantages of the template method for lateral distribution of multiple sources in treatment of laterally infiltrating gynecologic cancer, when compared to a conventional technique with colpostats. Biological doses in time dose fractionation (TDF), ret and reu units are calculated for the two treatment methods. With the template method the lateral dose (point B) is raised without significantly increasing the doses to the rectum and bladder, that is, relatively, the calculated biological doses at point A and B are more nearly equivalent and the doses to the rectum and bladder are significantly lower than the dose to point B.

  11. Biology and Soft Matter | ornl.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials Find Find More LikeAndreasHelp(SC) BiologicalBiology

  12. Final Design Completion The Comprehensive Final Design Review1

    E-Print Network [OSTI]

    Princeton Plasma Physics Laboratory

    a complete and satisfactory design basis for the system design. FMEAs should be performed and documented

  13. Designing decommissioning into new reactor designs

    SciTech Connect (OSTI)

    Devgun, J.S.; CHMM, Ph.D. [Nuclear Power Technologies, Sargent and Lundy LLC, Chicago, IL (United States)

    2007-07-01T23:59:59.000Z

    One of the lessons learned from decommissioning of existing reactors has been that decommissioning was not given much thought when these reactors were designed some three or four decades ago. Recently, the nuclear power has seen a worldwide resurgence and many new advanced reactor designs are either on the market or nearing design completion. Most of these designs are evolutionary in nature and build on the existing and proven technologies. They also incorporate many improvements and take advantage of the substantial operating experience. Nevertheless, by and large, the main factors driving the design of new reactors are the safety features, safeguards considerations, and the economic factors. With a large decommissioning experience that already exists in the nuclear industry, and with average decommissioning costs at around six hundred million dollars for each reactor in today's dollars, it is necessary that decommissioning factors also be considered as a part of the early design effort. Even though decommissioning may be sixty years down the road from the time they go on line, it is only prudent that new designs be optimized for eventual decommissioning, along with the other major considerations. (authors)

  14. Sharing tacit design knowledge in a distributed design environment

    E-Print Network [OSTI]

    Woo, Jeong-Han

    2006-10-30T23:59:59.000Z

    investigates the impact of tacit design knowledge on design performance in a distributed design environment supported by CMC software. The software was developed and tested in three design studios in which design students sought advice from experts in remote...

  15. Systems Modeling for Prognostic Cancer Biology

    E-Print Network [OSTI]

    Maccabe, Barney

    goal of this research is the development of personalized treatments in cancer, based on the genomic and treatment. A major challenge in contemporary cancer diagnosis and treatment is the development Systems Modeling for Prognostic Cancer Biology Xuefei Wang1 , BaiLian Li2 , Cheryl L. Willman

  16. Statistical Applications in Genetics and Molecular Biology

    E-Print Network [OSTI]

    California at Berkeley, University of

    groups of childhood leukemia patients: acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL testing, preprocessing, leukemia, tail probability Merrill D. Birkner is a trainee of the U.C. Berkeley of the Northern California Childhood Leukemia Study, for access to the biological samples. This study

  17. Energy use by biological protein transport pathways

    E-Print Network [OSTI]

    Economou, Tassos

    Energy use by biological protein transport pathways Nathan N. Alder1 and Steven M. Theg2 1 of metabolic energy, using the free energy of ATP and GTP hydrolysis and/or a transmembrane protonmotive force provided insights into the mechanisms of energy transduction, force generation and energy use by different

  18. Biological effectiveness of neutrons: Research needs

    SciTech Connect (OSTI)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01T23:59:59.000Z

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  19. Bioreactor Development for Biological Hydrogen Production

    E-Print Network [OSTI]

    Bioreactor Development for Biological Hydrogen Production Edward J. Wolfrum, Andrew S. Watt, Jie and reactor pressure on the volumetric pro- ductivity of trickle bed bioreactors. The apparent rate constant research focuses on using well- defined bioreactor geometries to collect quantitative reactor performance

  20. Genome Biology 2004, 6:302 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Gent, Universiteit

    Genome Biology 2004, 6, Technologiepark 927, B-9052 Ghent, Belgium. E-mail: Yves.vandepeer@psb.ugent.be Published: 21 December 2004 Genome at http://genomebiology.com/2004/6/1/302 © 2004 BioMed Central Ltd A report on the Plant Genomics European

  1. Molecular Biology Basics Planning Restriction Enzyme Digests

    E-Print Network [OSTI]

    Aris, John P.

    Molecular Biology Basics Planning Restriction Enzyme Digests A. Checklist: Buffer type Addition of BSA Optimum temperature Number of units of enzyme B. Plan to digest DNA with an "excess" of enzyme activity. Plan for the "excess" to be divided between time of digestion and number of units of enzyme

  2. Apparatus for automated testing of biological specimens

    DOE Patents [OSTI]

    Layne, Scott P. (Los Angeles, CA); Beugelsdijk, Tony J. (Los Alamos, NM)

    1999-01-01T23:59:59.000Z

    An apparatus for performing automated testing of infections biological specimens is disclosed. The apparatus comprise a process controller for translating user commands into test instrument suite commands, and a test instrument suite comprising a means to treat the specimen to manifest an observable result, and a detector for measuring the observable result to generate specimen test results.

  3. VEHICLE USAGE AGREEMENT DEPARTMENT OF BIOLOGICAL SCIENCE

    E-Print Network [OSTI]

    Ronquist, Fredrik

    VEHICLE USAGE AGREEMENT DEPARTMENT OF BIOLOGICAL SCIENCE All drivers of vehicles must certify to the following: 1. I certify that I have a valid driver's license appropriate for the vehicle type and will abide belts. 2. I have read and understand the vehicle operating policies and procedures as defined

  4. Genome Biology 2005, 6:R47 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    and Computational Biology Unit, Laboratory of Genetics National Institute on Aging, National Institutes of Health on media that conveniently allowed reproduction. The advent of digital detectors in microscopy has that linearly measures the flux of light at different points in a cell or tissue. Almost all the vast clinical

  5. Composites comprising biologically-synthesized nanomaterials

    DOE Patents [OSTI]

    Curran, Seamus; Dias, Sampath; Blau, Werner; Wang, Jun; Oremland, Ronald S; Baesman, Shaun

    2013-04-30T23:59:59.000Z

    The present disclosure describes composite materials containing a polymer material and a nanoscale material dispersed in the polymer material. The nanoscale materials may be biologically synthesized, such as tellurium nanorods synthesized by Bacillus selenitireducens. Composite materials of the present disclosure may have optical limiting properties and find use in optical limiting devices.

  6. Institute for Multiscale Modeling of Biological Interactions

    SciTech Connect (OSTI)

    Paulaitis, Michael E; Garcia-Moreno, Bertrand; Lenhoff, Abraham

    2009-12-26T23:59:59.000Z

    The Institute for Multiscale Modeling of Biological Interactions (IMMBI) has two primary goals: Foster interdisciplinary collaborations among faculty and their research laboratories that will lead to novel applications of multiscale simulation and modeling methods in the biological sciences and engineering; and Building on the unique biophysical/biology-based engineering foundations of the participating faculty, train scientists and engineers to apply computational methods that collectively span multiple time and length scales of biological organization. The success of IMMBI will be defined by the following: Size and quality of the applicant pool for pre-doctoral and post-doctoral fellows; Academic performance; Quality of the pre-doctoral and post-doctoral research; Impact of the research broadly and to the DOE (ASCR program) mission; Distinction of the next career step for pre-doctoral and post-doctoral fellows; and Faculty collaborations that result from IMMBI activities. Specific details about accomplishments during the three years of DOE support for IMMBI have been documented in Annual Progress Reports (April 2005, June 2006, and March 2007) and a Report for a National Academy of Sciences Review (October 2005) that were submitted to DOE on the dates indicated. An overview of these accomplishments is provided.

  7. MASTER OF ENGINEERING Biological and Environmental Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    MASTER OF ENGINEERING Biological and Environmental Engineering Program Requirements Fall 2013 The Master of Engineering (MEng) is a professional degree program intended for those who have a Bachelors degree or equivalent in an engineering or closely related science field from a college or university

  8. MASTER OF ENGINEERING Biological and Environmental Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    MASTER OF ENGINEERING Biological and Environmental Engineering Program Requirements Fall 2014 The Master of Engineering (MEng) is a professional degree program intended for those who have a Bachelors degree or equivalent in an engineering or closely related science field from a college or university

  9. Artificial Homeostasis: Integrating Biologically Inspired Computing

    E-Print Network [OSTI]

    Kent, University of

    - mune systems and a novel artificial endocrine system. The natural counterparts of these three of these artificial systems to yield artificially homeostatic systems. The components develop in a common envi. Thus we propose to consider the artificial counterparts of these three biological systems. The use

  10. Brent Craig Christner Department of Biological Sciences

    E-Print Network [OSTI]

    Christner, Brent C.

    , 1996. Thesis advisor: John J. Rowe B.S., Molecular Biology and Biotechnology, Westminster College, New. Assistant Research Professor, August 2004-2006. Department of Land Resources and Environmental Sciences of John C. Priscu, Department of Land Resources and Environmental Sciences, Montana State University

  11. Brent Craig Christner Department of Biological Sciences

    E-Print Network [OSTI]

    Christner, Brent C.

    , Ohio, 1996. Thesis advisor: John J. Rowe B.S., Molecular Biology and Biotechnology, Westminster College Resources and Environmental Sciences, Montana State University, Bozeman, Montana. Postdoctoral Researcher, June 2002-August 2004. Laboratory of John C. Priscu, Department of Land Resources and Environmental

  12. Mentor Program Information Division of Biology

    E-Print Network [OSTI]

    Kaufman, Glennis A.

    Mentor Program Information Division of Biology 116 Ackert Hall Manhattan, KS 66506 Kansas State will never be released for public information unless requested by the mentor. It is used only if a current K-State student requests to speak with a specific mentor and is kept private until that time. However, it may

  13. Physics Meets Biology (LBNL Summer Lecture Series)

    ScienceCinema (OSTI)

    Chu, Steve [Director, LBNL

    2011-04-28T23:59:59.000Z

    Summer Lecture Series 2006: If scientists could take advantage of the awesomely complex and beautiful functioning of biologys natural molecular machines, their potential for application in many disciplines would be incalculable. Nobel Laureate and Director of the Lawrence Berkeley National Laboratory Steve Chu explores Possible solutions to global warming and its consequences.

  14. THE COMPARATIVE VALUE OF BIOLOGICAL CARBON SEQUESTRATION

    E-Print Network [OSTI]

    McCarl, Bruce A.

    THE COMPARATIVE VALUE OF BIOLOGICAL CARBON SEQUESTRATION BRUCE A. MCCARL, BRIAN C. MURRAY, AND UWE A. SCHNEIDER A. Abstract Carbon sequestration via forests and agricultural soils saturates over time to sequestration because of (1) an ecosystems limited ability to take up carbon which we will call saturation

  15. Synthetic biology and the conservation of biodiversity

    E-Print Network [OSTI]

    Redford, Kent H.; Adams, William; Carlson, Rob; Mace, Georgina M.; Ceccarelli, Bertina

    2014-04-22T23:59:59.000Z

    reference to previous debates about land acquisition to grow biofuels, the production 202 of biologically-based chemicals and plastics, and the industrial burning of biomass. 203 Yet not all technologies are the same, nor are the people who use them...

  16. Biological consequences of Chernobyl: 20 years on

    E-Print Network [OSTI]

    Mousseau, Timothy A.

    Biological consequences of Chernobyl: 20 years on Anders Pape Møller1 and Timothy A. Mousseau2 1, University of South Carolina, Columbia, SC 29208, USA The disaster at the Chernobyl nuclear power plant of the four nuclear reactors of the Chernobyl nuclear power plant exploded on 26 April 1986 as a consequence

  17. Genome Biology 2003, 4:R43 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    Kellis, Manolis

    , Massachusetts Institute of Technology, Cambridge, MA 02139, USA. §Whitehead/MIT Center for Genome Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ¶Department of Genome conserved word pairs associated with gene-expression changes in yeastsTranscriptional regulation

  18. Methodology in Biological Game Simon M. Huttegger

    E-Print Network [OSTI]

    Zollman, Kevin

    ;Huttegger and Zollman Methodology in Biological Game Theory ESS Method Describe a game Find all the stable states (ESS) If there is only one, conclude this one is evolutionarily significant #12;Huttegger An Evolutionarily Stable Strategy (ESS) Pooling equilibrium Not an ESS Hybrid equilibrium Not an ESS #12;Huttegger

  19. Characterization and Control of Biological Microrobots

    E-Print Network [OSTI]

    magnetic system is five orders-of-magnitude less than the propulsion force gener- ated by the flagellum proposed for propulsion: extracting energy from an ex- ternal magnetic field [4], or extracting energy from of Magnetotactic Bacterium (MTB) which can be considered as a biological microrobot. Magnetic dipole moment

  20. School of Biological Sciences Undergraduate Scholarships & Awards

    E-Print Network [OSTI]

    Barrett, Jeffrey A.

    School of Biological Sciences Undergraduate Scholarships & Awards The following items are due not submit any additional items. 4. Award winners will be notified during the middle of May. 5. To be eligible for any Bio Sci Scholarships/Awards you must be a U.S. citizen, an eligible non

  1. Increasing Public Involvement in Structural Biology

    E-Print Network [OSTI]

    Baker, David

    --often referred to as citizen science--provides a means of engaging people's skills, rather than just for the public to get actively involved in structural biology research? Citizen science projects can require areas for citizen science as structural problems both are amenable to human spatial-reasoning skills

  2. Genome Biology 2007, 8:R34 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation

    E-Print Network [OSTI]

    Shneiderman, Ben

    Genome Biology 2007, 8:R34 analytics tool for genome assemblies Michael C Schatz*, Adam M Phillippy*, Ben Shneiderman and Steven L the original work is properly cited. Hawkeye: a visual analytics tool for genome assembliesHawkeye is a new

  3. Simultaneous wastewater treatment and biological electricity generation

    E-Print Network [OSTI]

    Simultaneous wastewater treatment and biological electricity generation B.E. Logan Department accomplishing wastewater treatment in processes based on microbial fuel cell technologies. When bacteria oxidize.4 £ 106 L of wastewater, a wastewater treatment plant has the potential to become a 2.3 MW power plant

  4. Nanotechnology: emerging tools for biology and medicine

    E-Print Network [OSTI]

    Bhatia, Sangeeta

    REVIEW Nanotechnology: emerging tools for biology and medicine Ian Y. Wong,1,2,10 Sangeeta N administration of thera- peutic treatments. Nanotechnology has the potential to transform these paradigms and physical functionality at small length scales. Here, we review nanotechnology- based approaches

  5. GOVERNANCE DOCUMENT DEPARTMENT OF INTEGRATIVE BIOLOGY

    E-Print Network [OSTI]

    Lajeunesse, Marc J.

    1 GOVERNANCE DOCUMENT DEPARTMENT OF INTEGRATIVE BIOLOGY January 23, 2014 The faculty otherwise specified, the following document refers to the IB Department and its personnel only. 1 with the Regular Faculty. The Search Committee will develop a list of candidates, manage the interviews

  6. Energy design for architects

    SciTech Connect (OSTI)

    Shaw, A. (ed.)

    1989-01-01T23:59:59.000Z

    This book contains techniques for energy efficiency in architectural design. Many aspects are covered including: cost; comfort and health; energy use; the design process; and analytical techniques. 202 figs. (JF)

  7. Designated Team Leader

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    For Designated Team Leader Each user project is coordinated by a Designated Team Leader (DTL) who may also be the Principal Investigator (PI). The DTL must provide details of all...

  8. Design of intelligent interiors

    E-Print Network [OSTI]

    Bonanni, Leonardo Amerigo, 1977-

    2005-01-01T23:59:59.000Z

    Ubiquitous computing is transforming interior design by allowing utilities, goods and information to be delivered where and when we need them. How will new information technologies impact the design of interior spaces? ...

  9. System Design Stage

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-05-21T23:59:59.000Z

    This chapter addresses translating the user-oriented functional design specifications into a set of technical, computer-oriented system design specifications; and designing the data structure and processes to the level of detail necessary to plan and execute the Programming and Installation Stages.

  10. Pavement Thickness Design Parameter

    E-Print Network [OSTI]

    Pavement Thickness Design Parameter Impacts 2012 Municipal Streets Seminar November 14, 2012 Paul D. Wiegand, P.E. #12;Pavement Thickness Design · How do cities decide how thick to build their pavements;Pavement Thickness Design · Correct answer ­ A data-based analysis! · Doesn't have to be difficult and time

  11. Shock Tube Design

    E-Print Network [OSTI]

    Koppenberger, Peter K.

    2010-07-14T23:59:59.000Z

    , and provide two driver sections to allow for dual shock capability. The tube was designed to accommodate a 2.5 MACH shockwave, and incorporated a factor of safety of 3 in the design. A modular approach to design was followed to allow further diversification...

  12. Biologically Plausible Neural Model for the Recognition of Biological Motion and Actions

    E-Print Network [OSTI]

    Giese, Martin Alexander

    2002-08-01T23:59:59.000Z

    The visual recognition of complex movements and actions is crucial for communication and survival in many species. Remarkable sensitivity and robustness of biological motion perception have been demonstrated in ...

  13. BIOLOGICAL AND MICROBIAL CONTROL Biology and Rearing of Cleruchoides noackae (Hymenoptera

    E-Print Network [OSTI]

    : Mymaridae), an Egg Parasitoid for the Biological Control of Thaumastocoris peregrinus (Hemiptera egg para- sitoid of Thaumastocoris peregrinus Carpintero and Dellape´ (Hemiptera: Thaumastocoridae peregrinus Carpintero and Dellape´ (Hemiptera: Thaumastocoridae) is a se- rious and widespread pest

  14. ENVIRONMENTAL DESIGN CONSULTANTS + LIGHTING DESIGNERS | atelierten.com Sustainable Design

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    -fitting of renewable energy systems or other technologies. Create a high-performance, energy efficient, thermally Strategies · Proposed Design & Alternate Energy Efficiency Measures · Earth Duct analysis · High Performance zero energy, carbon, and water performance. · Improve campus connectivity and exemplify best practices

  15. Foundation Design Handbook

    SciTech Connect (OSTI)

    Carmody, John [Center for Sustainable Building Research, University of Minnesota; Mosiman, Garrett [Center for Sustainable Building Research, University of Minnesota; Handeen, Daniel [Center for Sustainable Building Research, University of Minnesota; Huelman, Patrick [Cold Climate Housing Program, University of Minnesota; Christian, Jeffery [Oak Ridge National Laboratory

    2013-10-01T23:59:59.000Z

    The purpose of this handbook is to provide information that will enable designers, builders, and homeowners to understand foundation design problems and solutions. The foundation of a house is a somewhat invisible and sometimes ignored component of the building. It is increasingly evident, however, that attention to good foundation design and construction has significant benefits to the homeowner and the builder, and can avoid some serious future problems. Good foundation design and construction practice means not only insulating to save energy, but also providing effective structural design as well as moisture, termite, and radon control techniques where appropriate.

  16. Attached sunspace design analysis

    SciTech Connect (OSTI)

    Jones, R.W.; McFarland, R.D.

    1981-01-01T23:59:59.000Z

    An introduction to new design analysis information for attached sunspaces is presented. The 28 sunspace reference designs are described. Note is taken of those designs (the semi-enclosed geometries) analyzed more recently than the previously published reports. The role of sensitivity studies is discussed, and some sample plots of sunspace performance sensitivity to key design parameters are presented. The monthly solar load ratio (SLR) correlations are reviewed with emphasis on the modified SLR used in the sunspace analysis. The application of the sunspace SLR correlations to monthly design analysis is outlined.

  17. Three-dimensionally printed biological machines powered by skeletal muscle

    E-Print Network [OSTI]

    Chan, Vincent

    Combining biological components, such as cells and tissues, with soft robotics can enable the fabrication of biological machines with the ability to sense, process signals, and produce force. An intuitive demonstration of ...

  18. AGRICULTURAL & BIOLOGICAL ENGINEERING FALL 2013 INSIDE THIS ISSUE

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL & BIOLOGICAL ENGINEERING FALL 2013 INSIDE THIS ISSUE: · ABESpring of Agricultural and Biological Engineering of the College of Agricultural, Consumer and Environmental Sciences and the College of Engineering at the University of Illinois at Urbana Champaign. 338 Agricultural Engineering

  19. Multispectral optical tweezers for molecular diagnostics of single biological cells

    E-Print Network [OSTI]

    Wu, Shin-Tson

    Multispectral optical tweezers for molecular diagnostics of single biological cells Author, Townes Laser Institute, CREOL ­ The College of Optics and Photonics, Univ. of Central Florida (United States) ABSTRACT Optical trapping of single biological cells has become an established technique

  20. MS.BIOLOGY.NON-THESIS ACADEMIC LEARNING PLAN

    E-Print Network [OSTI]

    O'Laughlin, Jay

    to constructive feedback Job Prospects for Biology Graduates MS/non-thesis in Biology Bioremediation Biotechnology Medical Research Industry Government Education Microbiology Health Professions Research Laboratories Find Food Production Pollution Control Environmental Diagnostics Forestry Agriculture #12;MS

  1. What Was Life? Answers from Three Limit Biologies

    E-Print Network [OSTI]

    Helmreich, Stefan

    2011-01-01T23:59:59.000Z

    What is life? A gathering consensus in anthropology, science studies, and philosophy of biology suggests that the theoretical object of biology, “life,” is today in transformation, if not dissolution. Proliferating ...

  2. Biochemistry & Molecular Biology Department of Environmental and Biomolecular Systems

    E-Print Network [OSTI]

    Chapman, Michael S.

    Biology _____ _____ _____ EBS 514 ­ Biochemistry III: Metabolism and Bioenergetics Biology _____ _____ _____ EBS 614 ­ Biochemistry III: Metabolism and Bioenergetics _____ _____ _____ Three (3) of the following courses are required: EBS 625 ­ Bioenergetics and Membrane Transport

  3. Project 198740100 Assessment of Smolt Condition: Biological and Environmental Interactions

    E-Print Network [OSTI]

    1 Project 198740100 Assessment of Smolt Condition: Biological and Environmental Interactions detailed investigations of environmental and biological factors that influence smolt development environmental factors influence fish development, condition, and long-term survival. The proposed tasks describe

  4. Chemistry meets biology in colitis-associated carcinogenesis

    E-Print Network [OSTI]

    Mangerich, Aswin

    The intestine comprises an exceptional venue for a dynamic and complex interplay of numerous chemical and biological processes. Here, multiple chemical and biological systems, including the intestinal tissue itself, its ...

  5. Boston University Physics Colloquium Microscale propulsion in biological and

    E-Print Network [OSTI]

    Mohanty, Raj

    Boston University Physics Colloquium Microscale propulsion in biological and engineered systems biological locomotion and engineered propulsion. In the first example, we examine swimming microorganisms the microstructure. In the second example, we examine engineered magnetic artificial microswimmers which can

  6. Drug Discovery and Development from Marine Biology-Based Research

    E-Print Network [OSTI]

    Jawitz, James W.

    Drug Discovery and Development from Marine Biology- Based Research Oceanyx Pharmaceuticals is a novel drug discovery and development company that leverages marine biology-based natural identified two lead candidates, largazole and apratoxin, as potential drug candidates for the treatment

  7. Nitrogen Atmospheric Pressure Post Discharges for Surface Biological Decontamination inside

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Nitrogen Atmospheric Pressure Post Discharges for Surface Biological Decontamination inside Small) (PET) capillary tubes of different shapes and lengths and decontamination of flow tubes, both for several years at the Orsay Plasma Lab. Its biological decontamination efficiency has been demonstrated

  8. Biological Production of Hydrogen DOE Office of Science,

    E-Print Network [OSTI]

    .Houghton@science.doe.gov #12;Biology transforms energy in a series ofBiology transforms energy in a series University Artificial Chromosome: Minimum Genome Oligo Assembly Microalgae production facility of Cyanotech

  9. Complex biological and bio-inspired systems

    SciTech Connect (OSTI)

    Ecke, Robert E [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    The understanding and characterization ofthe fundamental processes of the function of biological systems underpins many of the important challenges facing American society, from the pathology of infectious disease and the efficacy ofvaccines, to the development of materials that mimic biological functionality and deliver exceptional and novel structural and dynamic properties. These problems are fundamentally complex, involving many interacting components and poorly understood bio-chemical kinetics. We use the basic science of statistical physics, kinetic theory, cellular bio-chemistry, soft-matter physics, and information science to develop cell level models and explore the use ofbiomimetic materials. This project seeks to determine how cell level processes, such as response to mechanical stresses, chemical constituents and related gradients, and other cell signaling mechanisms, integrate and combine to create a functioning organism. The research focuses on the basic physical processes that take place at different levels ofthe biological organism: the basic role of molecular and chemical interactions are investigated, the dynamics of the DNA-molecule and its phylogenetic role are examined and the regulatory networks of complex biochemical processes are modeled. These efforts may lead to early warning algorithms ofpathogen outbreaks, new bio-sensors to detect hazards from pathomic viruses to chemical contaminants. Other potential applications include the development of efficient bio-fuel alternative-energy processes and the exploration ofnovel materials for energy usages. Finally, we use the notion of 'coarse-graining,' which is a method for averaging over less important degrees of freedom to develop computational models to predict cell function and systems-level response to disease, chemical stress, or biological pathomic agents. This project supports Energy Security, Threat Reduction, and the missions of the DOE Office of Science through its efforts to accurately model biological systems at the molecular and cellular level. The project's impact encompasses applications to biofuels, to novel sensors and to materials with broad use for energy or threat reduction. The broad, interdisciplinary approach of CNLS offers the unparalleled strength of combining science backgrounds and expertise -a unique and important asset in attacking the complex science of biological organisms. This approach also allows crossfertilization, with concepts and techniques transferring across field boundaries.

  10. Critical Waves and the Length Problem of Biology

    E-Print Network [OSTI]

    R. B. Laughlin

    2015-04-17T23:59:59.000Z

    It is pointed out that the mystery of how biological systems measure their lengths vanishes away if one premises that they have discovered a way to generate linear waves analogous to compressional sound. These can be used to detect length at either large or small scales using echo timing and fringe counting. It is shown that suitable linear chemical potential waves can, in fact, be manufactured by tuning to criticality conventional reaction-diffusion with a small number substances. Min oscillations in E. coli are cited as precedent resonant length measurement using chemical potential waves analogous to laser detection. Mitotic structures in eucaryotes are identified as candidates for such an effect at higher frequency. The engineering principle is shown to be very general and functionally the same as that used by hearing organs. PNAS Significance Statement: This paper invokes physical principles to address the question of how living things might use reaction-diffusion to measure out and regulate the many thousands of lengths required to make their body parts and internal organs. It argues that two ideas have been missing. One is that oscillation is necessary to achieve the necessary design stability and plasticity. The other is that the system must be tuned to criticality to stabilize the propagation velocity, thus enabling clocks to function as meter sticks. The broader significance is twofold: First, a fundamental piece of the machinery of life is probably invisible to present-day biochemical methods because they are too slow. Second, the simplicity of growth and form identified a century ago by D'Arcy Thompson is probably a symptom of biological engineering strategies, not primitive law.

  11. Biological Information Document, Radioactive Liquid Waste Treatment Facility

    SciTech Connect (OSTI)

    Biggs, J.

    1995-12-31T23:59:59.000Z

    This document is intended to act as a baseline source material for risk assessments which can be used in Environmental Assessments and Environmental Impact Statements. The current Radioactive Liquid Waste Treatment Facility (RLWTF) does not meet current General Design Criteria for Non-reactor Nuclear Facilities and could be shut down affecting several DOE programs. This Biological Information Document summarizes various biological studies that have been conducted in the vicinity of new Proposed RLWTF site and an Alternative site. The Proposed site is located on Mesita del Buey, a mess top, and the Alternative site is located in Mortandad Canyon. The Proposed Site is devoid of overstory species due to previous disturbance and is dominated by a mixture of grasses, forbs, and scattered low-growing shrubs. Vegetation immediately adjacent to the site is a pinyon-juniper woodland. The Mortandad canyon bottom overstory is dominated by ponderosa pine, willow, and rush. The south-facing slope was dominated by ponderosa pine, mountain mahogany, oak, and muhly. The north-facing slope is dominated by Douglas fir, ponderosa pine, and oak. Studies on wildlife species are limited in the vicinity of the proposed project and further studies will be necessary to accurately identify wildlife populations and to what extent they utilize the project area. Some information is provided on invertebrates, amphibians and reptiles, and small mammals. Additional species information from other nearby locations is discussed in detail. Habitat requirements exist in the project area for one federally threatened wildlife species, the peregrine falcon, and one federal candidate species, the spotted bat. However, based on surveys outside of the project area but in similar habitats, these species are not expected to occur in either the Proposed or Alternative RLWTF sites. Habitat Evaluation Procedures were used to evaluate ecological functioning in the project area.

  12. Biologically Inspired Photocatalytically Active Membranes for Water Treatment

    E-Print Network [OSTI]

    Kinsinger, Nichola

    2013-01-01T23:59:59.000Z

    wastewater treatment systems include treatment of the influent by a series of stages: pretreatment, primary sedimentation, biological

  13. Design Space Exploration of Parameterized Systems using Design of Experiments

    E-Print Network [OSTI]

    Sheldon, David

    2011-01-01T23:59:59.000Z

    is known as a full factorial design: --- (A off, B off, Cknown as fractional factorial design involving experimentsetc. ) of the full factorial design. Numerous fractional

  14. 6th Annual Systems Biology Symposium: Systems Biology and the Environment

    SciTech Connect (OSTI)

    Galitski, Timothy, P.

    2007-04-01T23:59:59.000Z

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology is an annual two-day event gathering the most influential researchers transforming biology into an integrative discipline investigating complex systems. In recognition of the fundamental similarity between the scientific problems addressed in environmental science and systems biology studies at the molecular, cellular, and organismal levels, the 2007 Symposium featured global leaders in “Systems Biology and the Environment.” The objective of the 2007 “Systems Biology and the Environment” International Symposium was to stimulate interdisciplinary thinking and research that spans systems biology and environmental science. This Symposium was well aligned with the DOE’s Genomics:GTL program efforts to achieve scientific objectives for each of the three DOE missions: • Develop biofuels as a major secure energy source for this century, • Develop biological solutions for intractable environmental problems, and • Understand biosystems’ climate impacts and assess sequestration strategies Our scientific program highlighted world-class research exemplifying these priorities. The Symposium featured 45 minute lectures from 12 researchers including: Penny/Sallie Chisholm of MIT gave the keynote address “Tiny Cells, Global Impact: What Prochlorococcus Can Teach Us About Systems Biology”, plus Jim Fredrickson of PNNL, Nitin Baliga of ISB, Steve Briggs of UCSD, David Cox of Perlegen Sciences, Antoine Danchin of Institut Pasteur, John Delaney of the U of Washington, John Groopman of Johns Hopkins, Ben Kerr of the U of Washington, Steve Koonin of BP, Elliott Meyerowitz of Caltech, and Ed Rubin of LBNL. The 2007 Symposium promoted DOE’s three mission areas among scientists from multiple disciplines representing academia, non-profit research institutions, and the private sector. As in all previous Symposia, we had excellent attendance of participants representing 20-30 academic or research-oriented facilities along with 25-30 private corporations from 5-10 countries. To broaden the audience for the Symposium and ensure the continued accessibility of the presentations, we made the presentation videos available afterward on the ISB’s website.

  15. College of Biology and Agriculture (801) 422-3963

    E-Print Network [OSTI]

    Hart, Gus

    College of Biology and Agriculture 301 WIDB (801) 422-3963 Internet: http://bioag.byu.edu Dean are included within the College of Biology and Agriculture: Integrative Biology (InBio) Microbiology science. Agricultural sciences address three of the great dilemmas facing mankind in the twenty

  16. Roadmap: Biology -Bachelor of Arts [AS-BA-BSCI

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Biology - Bachelor of Arts [AS-BA-BSCI] College of Arts and Sciences Department of Biological Sciences Catalog Year: 2012­2013 Page 1 of 3 | Last Updated: 2-May-12/LNHD This roadmap hours and minimum 42 upper- division credit hours #12;Roadmap: Biology - Bachelor of Arts [AS

  17. Directed evolution: an evolving and enabling synthetic biology tool

    E-Print Network [OSTI]

    Zhao, Huimin

    Directed evolution: an evolving and enabling synthetic biology tool Ryan E Cobb1 , Tong Si1 remains a valuable tool for synthetic biology, enabling the identification of desired functionalities from biological entity with the intent of identifying those with desired proper- ties. While a powerful tool

  18. Conservation Practice and Policy Taking the Conservation Biology Perspective

    E-Print Network [OSTI]

    DeSalle, Rob

    to transform the topics of conservation biology research into environmental-issue and ecology topics, the major (environmental issues). Many studies published in Conservation Biology are related in some way to the ecological of their effect on the world. Keywords: conservation biology, ecology education, education, environmental

  19. PLoS Computational Biology: A New Community Journal

    E-Print Network [OSTI]

    Editorial PLoS Computational Biology: A New Community Journal Philip E. Bourne, Steven E. Brenner, Michael B. Eisen W elcome to PLoS Computation- al Biology, a community journal from the Public Li- brary of Science dedicated to reporting biological advances achieved through computation. The journal is published

  20. Applications of microfluidics in chemical biology Douglas B Weibel1

    E-Print Network [OSTI]

    Prentiss, Mara

    Applications of microfluidics in chemical biology Douglas B Weibel1 and George M Whitesides2 This review discusses the application of microfluidics in chemical biology. It aims to introduce the reader to microfluidics, describe characteristics of microfluidic systems that are useful in studying chemical biology

  1. November 2009 Peter Fratzl 1 MPG 2010+: BIOLOGICAL MATERIALS SCIENCES

    E-Print Network [OSTI]

    recognized that material properties can be critical for the biological function of molecules, tissuesNovember 2009 Peter Fratzl 1 MPG 2010+: BIOLOGICAL MATERIALS SCIENCES At a glance: A new field at the interface between biology and the materials sciences helps elucidating structure-function relations

  2. Math 574 --Optimization Models in Computational Biology (Spring 2008)

    E-Print Network [OSTI]

    Krishnamoorthy, Bala

    Bioinformatics and computational biology (BCB) is one of the "hottest" interdisciplinary areas of sci- ence todayMath 574 -- Optimization Models in Computational Biology (Spring 2008) Course Title Topics in Optimization: Models in Computational Biology Time Tue-Thu 12:00­1:15 pm Credits 3 Location Webster B12

  3. NIH WORKING DEFINITION OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY

    E-Print Network [OSTI]

    Rau, Don C.

    NIH WORKING DEFINITION OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY July 17, 2000 The following working definition of bioinformatics and computational biology were developed by the BISTIC Definition Liu Preamble Bioinformatics and computational biology are rooted in life sciences as well as computer

  4. 2006 Reversible Associations in Structural and Molecular Biology Conference-January 15-20, 2006

    SciTech Connect (OSTI)

    Gary Ackers

    2007-04-10T23:59:59.000Z

    Many biological processes are carried out through the formation of macromolecular complexes, ranging from the simplest conformational organization to the most sophisticated interactions among complexes themselves. Reversible associations generate specific local conformations, active site configurations, and subunit--subunit interfaces, and encompass larger scale quaternary rearrangements and dissociation events. Assembled complexes exhibit properties different from those of component parts, such that 'the whole is greater than the sum of the parts', resulting in biological functioning of the assembly. This Gordon Research Conference brings together researchers from what may appear to be disparate fields with the common focus of applying quantitative kinetic and thermodynamic analysis to reversible macromolecular interactions. This conference will include the following session topics: (1) Protein design in evolution and recognition; (2) Emerging technologies; (3) Single molecule mechanics; (4) Nucleic acid/protein recognition; (5) Lipid/protein recognition; (6) Protein switches and networks; (7) Advances in classic technologies; (8) Ligand/macromolecule complexes and drug design; and (9) Selected student oral presentations; all from the perspective of reversibly associating systems. A wide array of techniques are typically covered, from single molecule to computational methods, chromatography and analytical ultracentrifugation, spectroscopic dynamics and titration calorimetry. The quantitative analysis of assembled complexes demonstrates that these biologically important functions depend not just upon a single part of the molecule, but on the coordination brought about by the ensemble of interactions. Applications from graduate students and young postdoctoral scientists are welcomed. A selection of short talks will be invited from students presenting posters.

  5. 2009 Archaea: Ecology, Metabolism & Molecular Biology GRC

    SciTech Connect (OSTI)

    Dr. Julie Maupin- Furlow

    2009-07-26T23:59:59.000Z

    Archaea, one of three major evolutionary lineages of life, are a fascinating and diverse group of microbes with deep roots overlapping those of eukaryotes. The focus of the 'Archaea: Ecology Metabolism & Molecular Biology' GRC conference expands on a number of emerging topics highlighting new paradigms in archaeal metabolism, genome function and systems biology; information processing; evolution and the tree of life; the ecology and diversity of archaea and their viruses; and industrial applications. The strength of this conference lies in its ability to couple a field with a rich history in high quality research with new scientific findings in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  6. 2011 Archaea: Ecology, Metabolism, & Molecular Biology

    SciTech Connect (OSTI)

    Keneth Stedman

    2011-08-05T23:59:59.000Z

    Archaea, one of three major evolutionary lineages of life, are a fascinating and diverse group of microbes with deep roots overlapping those of eukaryotes. The focus of the 'Archaea: Ecology Metabolism & Molecular Biology' GRC conference expands on a number of emerging topics highlighting new paradigms in archaeal metabolism, genome function and systems biology; information processing; evolution and the tree of life; the ecology and diversity of archaea and their viruses. The strength of this conference lies in its ability to couple a field with a rich history in high quality research with new scientific findings in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  7. Radiation physics, biophysics, and radiation biology

    SciTech Connect (OSTI)

    Hall, E.J.; Zaider, M.

    1993-05-01T23:59:59.000Z

    Research at the Center for Radiological Research is a multidisciplenary blend of physics, chemistry and biology aimed at understanding the mechanisms involved in the health problems resulting from human exposure to ionizing radiations. The focus is increased on biochemistry and the application of the techniques of molecular biology to the problems of radiation biology. Research highlights of the program from the past year are described. A mathematical model describing the production of single-strand and double-strand breaks in DNA as a function radiation quality has been completed. For the first time Monte Carlo techniques have been used to obtain directly the spatial distribution of DNA moieties altered by radiation. This information was obtained by including the transport codes a realistic description of the electronic structure of DNA. We have investigated structure activity relationships for the potential oncogenicity of a new generation of bioreductive drugs that function as hypoxic cytotoxins. Experimental and theoretical investigation of the inverse dose rate effect, whereby medium LET radiations actually produce an c effect when the dose is protracted, is now at a point where the basic mechanisms are reasonably understood and the complex interplay between dose, dose rate and radiation quality which is necessary for the effect to be present can now be predicted at least in vitro. In terms of early radiobiological damage, a quantitative link has been established between basic energy deposition and locally multiply damaged sites, the radiochemical precursor of DNA double strand breaks; specifically, the spatial and energy deposition requirements necessary to form LMDs have been evaluated. For the first time, a mechanically understood biological fingerprint'' of high-LET radiation has been established. Specifically measurement of the ratio of inter-to intra-chromosomal aberrations produces a unique signature from alpha-particles or neutrons.

  8. On a Model of Superconductivity and Biology

    E-Print Network [OSTI]

    Monica De Angelis

    2012-03-02T23:59:59.000Z

    The paper deals with a semilinear integrodifferential equation that characterizes several dissipative models of Viscoelasticity, Biology and Superconductivity. The initial - boundary problem with Neumann conditions is analyzed. When the source term F is a linear function, then the explicit solution is obtained. When F is non linear, some results on existence, uniqueness and a priori estimates are deduced. As example of physical model the reaction - diffusion system of Fitzhugh Nagumo is considered.

  9. Investigation of Trace Uranium in Biological Matrices 

    E-Print Network [OSTI]

    Miller, James Christopher

    2013-05-31T23:59:59.000Z

    . This monitoring is often multi-faceted and typically involves an air sampling and biological sampling regime. The regime depends on the potential for exposures, the materials and chemical compounds being used, and the facility history. Specifically... Y-12 led the early US uranium enrichment programs, it also pioneered early uranium bioassay.[8] Likewise, the 5 Savannah River Site (SRS) pioneered plutonium bioassay techniques.[9] From these programs, techniques were developed to detect...

  10. 2004 Reversible Associations in Structure & Molecular Biology

    SciTech Connect (OSTI)

    Edward Eisenstein Nancy Ryan Gray

    2005-03-23T23:59:59.000Z

    The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

  11. KPFM and PFM of Biological Systems

    SciTech Connect (OSTI)

    Rodriguez, Brian [University College, Dublin; Kalinin, Sergei V [ORNL

    2011-01-01T23:59:59.000Z

    Surface potentials and electrostatic interactions in biological systems are a key element of cellular regulation and interaction. Examples include cardiac and muscular activity, voltage-gated ion channels, protein folding and assembly, and electroactive cells and electrotransduction. The coupling between electrical, mechanical, and chemical signals and responses in cellular systems necessitates the development of tools capable of measuring the distribution of charged species, surface potentials, and mechanical responses to applied electrical stimuli and vice versa, ultimately under physiological conditions. In this chapter, applications of voltage-modulated atomic force microscopy (AFM) methods including Kelvin probe force microscopy (KPFM) and piezoresponse force microscopy (PFM) to biological systems are discussed. KPFM is a force-sensitive non-contact or intermittent-contact mode AFM technique that allows electrostatic interactions and surface potentials to be addressed. Beyond long-range electrostatic interactions, the application of bias can lead to a mechanical response, e.g., due to linear piezoelectric coupling in polar biopolymers or via more complex electrotransduction and redox pathways in other biosystems. The use and development of PFM, based on direct electromechanical detection, to biological systems will also be addressed. The similarities and limitations of measuring surface potentials and electromechanical coupling in solution will be outlined.

  12. Biological Hydrogen Production Using Synthetic Wastewater Biotin and glutamic acid are not required for biological hydrogen production.

    E-Print Network [OSTI]

    Barthelat, Francois

    Biological Hydrogen Production Using Synthetic Wastewater Conclusion ·Biotin and glutamic acid are not required for biological hydrogen production. ·MgSO4 .7H2O is a required nutrient, but hydrogen production work should focus on minimizing the lag time in biological hydrogen production, by varying nutrient

  13. Race to Zero Design Competition Webinar: Housing Design Best...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Race to Zero Design Competition Webinar: Housing Design Best Practices Race to Zero Design Competition Webinar: Housing Design Best Practices November 18, 2014 1:00PM to 2:30PM EST...

  14. Cooperative Modeling and Design History Tracking Using Design Tracking Matrix

    E-Print Network [OSTI]

    Kim, Jonghyun

    2010-10-12T23:59:59.000Z

    This thesis suggests a new framework for cooperative modeling which supports concurrency design protocol with a design history tracking function. The proposed framework allows designers to work together while eliminating design conflicts...

  15. Information Architecture: The Design Behind The Design Presenter: Mary Peterson

    E-Print Network [OSTI]

    New Hampshire, University of

    Information Architecture: The Design Behind The Design Presenter: Mary Peterson Information architecture (often abbreviated "IA") is the practice of structuring information for a purpose. Organizing the information they require. User Centered Design Design the architecture around the needs and capabilities

  16. Magnetic shielding design analysis

    SciTech Connect (OSTI)

    Kerns, J.A.; LaPaz, A.D.; Fabyan, J.

    1983-12-27T23:59:59.000Z

    Two passive magnetic-shielding-design approaches for static external fields are reviewed. The first approach uses the shielding solutions for spheres and cylinders while the second approach requires solving Maxwell's equations. Experimental data taken at LLNL are compared with the results from these shieldings-design methods, and improvements are recommended for the second method. Design considerations are discussed here along with the importance of material gaps in the shield.

  17. Mechanizing Exploratory Game Design

    E-Print Network [OSTI]

    Smith, Adam Marshall

    2012-01-01T23:59:59.000Z

    machine think? ” [223], Alan Turing revives what is perhapsone day be designed, to Alan Turing’s 1950 hand-simulation

  18. Effective Design Strategies

    Broader source: Energy.gov [DOE]

    As described in the Whole Building Design Guide (WBDG), all Federal agencies are required to follow the Guiding Principles for New Construction and Major Renovations, which include considerations...

  19. Exercise Design Laboratory

    Broader source: Energy.gov [DOE]

    The Emergency Operations Training Academy (EOTA), NA 40.2, Readiness and Training, Albuquerque, NM is pleased to announce the EXR231, Exercise Design Laboratory course

  20. LSST Camera Optics Design

    SciTech Connect (OSTI)

    Riot, V J; Olivier, S; Bauman, B; Pratuch, S; Seppala, L; Gilmore, D; Ku, J; Nordby, M; Foss, M; Antilogus, P; Morgado, N

    2012-05-24T23:59:59.000Z

    The Large Synoptic Survey Telescope (LSST) uses a novel, three-mirror, telescope design feeding a camera system that includes a set of broad-band filters and three refractive corrector lenses to produce a flat field at the focal plane with a wide field of view. Optical design of the camera lenses and filters is integrated in with the optical design of telescope mirrors to optimize performance. We discuss the rationale for the LSST camera optics design, describe the methodology for fabricating, coating, mounting and testing the lenses and filters, and present the results of detailed analyses demonstrating that the camera optics will meet their performance goals.

  1. Radiation physics, biophysics, and radiation biology. Progress report, December 1, 1991--November 30, 1992

    SciTech Connect (OSTI)

    Hall, E.J.

    1992-05-01T23:59:59.000Z

    The following research programs from the Center for Radiological Research of Columbia University are described: Design and development of a new wall-less ultra miniature proportional counter for nanodosimetry; some recent measurements of ionization distributions for heavy ions at nanometer site sizes with a wall-less proportional counter; a calculation of exciton energies in periodic systems with helical symmetry: application to a hydrogen fluoride chain; electron energy-loss function in polynucleotide and the question of plasmon excitation; a non-parametric, microdosimetric-based approach to the evaluation of the biological effects of low doses of ionizing radiation; high-LET radiation risk assessment at medium doses; high-LET radiobiological effects: increased lesion severity or increased lesion proximity; photoneutrons generated by high energy medical linacs; the biological effectiveness of neutrons; implications for radiation protection; molecular characterization of oncogenes induced by neutrons; and the inverse dose-rate effect for oncogenic transformation by charged particles is LET dependent.

  2. Open collaborative system design : a strategic framework with application to synthetic biology

    E-Print Network [OSTI]

    Silver, Matthew Robin

    2010-01-01T23:59:59.000Z

    Across technology industries and particularly at the cutting edge of biotechnology a debate is under way about the proper balance between open and closed - between co-developing products with shared information and open ...

  3. Title: Stereology in a biological context with the integration of mathematics, design and modeling.

    E-Print Network [OSTI]

    Cooper, Robin L.

    content can be determined by direct counts (mco): Direct counts (mco)=[(0)(#of failures)+(1)(# of single (mco) one can directly count the number of evoked events: The trace shows two evoked events. See Methods for the equation to calculate mco. #12;3 Figure 2: 1st event is a failure, 2nd is a single

  4. Biologically enhanced cathode design for improved capacity and cycle life for lithium-oxygen batteries

    E-Print Network [OSTI]

    Oh, Dahyun

    Lithium-oxygen batteries have a great potential to enhance the gravimetric energy density of fully packaged batteries by two to three times that of lithium ion cells. Recent studies have focused on finding stable electrolytes ...

  5. Experimental Design and Inverse Problems in Plant Biological , H.T. Banks

    E-Print Network [OSTI]

    crop models, such as the Aquacrop model [15] and decision support system for agrotechnology transfer growth and crop yield. We use a dynamical system model proposed by Zhu., et al. [16], which describes with this dynamical system mathematical model and a statistical model to describe the observation process

  6. Energy absorbent natural materials and bioinspired design strategies: A review J. McKittrick a,b,

    E-Print Network [OSTI]

    Meyers, Marc A.

    Review Energy absorbent natural materials and bioinspired design strategies: A review J. Mc Keywords: Structural biological materials Energy absorption Bioinspired design Some of the most remarkable materials in terms of energy absorption and impact resistance are not found through human processing

  7. Abstract--Regarding to concrete industrial applications, we examined the functionality and the systematic design of a bionic

    E-Print Network [OSTI]

    Stryk, Oskar von

    and the systematic design of a bionic robot arm developed and driven by biologically inspired principles. Based "intelligent" control. II. DESIGN PRINCIPLE OF THE BIONIC ROBOT ARM The principle of the bionic drive of a 3 DOF Bionic Robot Arm Sebastian Klug1 , Bernhard Möhl2 , Oskar von Stryk1 and Oliver Barth3 1

  8. On the multiscale origins of fracture resistance in human bone and its biological degradation

    E-Print Network [OSTI]

    Zimmermann, Elizabeth A.

    2012-01-01T23:59:59.000Z

    and   its  biological  degradation   DISCLAIMER   This  and   its  biological  degradation   E.  A.  Zimmermanntissue  fails  due  to  degradation  of  the  collagen  

  9. Integrative multicellular biological modeling: a case study of 3D epidermal development using GPU algorithms

    E-Print Network [OSTI]

    Christley, Scott; Lee, Briana; Dai, Xing; Nie, Qing

    2010-01-01T23:59:59.000Z

    on Computational Biology and Bioinformatics 2005, 2:273-288.on Computational Biology and Bioinformatics 2005, 2:254-261.

  10. Concentration in Green Design

    E-Print Network [OSTI]

    Shewchuk, Jonathan

    , energy, infrastructure or transport. Participants in this specialization area work closely with the GreenConcentration in Green Design Research and Education Opportunities Carnegie Mellon University Civil and Environmental Engineering www.ce.cmu.edu M.S. Concentration Green Design - Course Only Track As an extension

  11. 2014 Design Report Introduction

    E-Print Network [OSTI]

    Rimon, Elon

    standard performance test procedures, laying a base line for next year's improvements. 2. Important design accuracy. 3. Decision making: Material and design: High strength Magnesium alloy was chosen for most parts in multiple load scenarios ­ turn, brake, acceleration and combined action. The final masses of the uprights

  12. Third international congress of plant molecular biology: Molecular biology of plant growth and development

    SciTech Connect (OSTI)

    Hallick, R.B. [ed.

    1995-02-01T23:59:59.000Z

    The Congress was held October 6-11, 1991 in Tucson with approximately 3000 scientists attending and over 300 oral presentations and 1800 posters. Plant molecular biology is one of the most rapidly developing areas of the biological sciences. Recent advances in the ability to isolate genes, to study their expression, and to create transgenic plants have had a major impact on our understanding of the many fundamental plant processes. In addition, new approaches have been created to improve plants for agricultural purposes. This is a book of presentation and posters from the conference.

  13. A Quantum Biological Switch Based on Superradiance Transitions

    E-Print Network [OSTI]

    D. Ferrari; G. L. Celardo; G. P. Berman; R. T. Sayre; F. Borgonovi

    2013-07-05T23:59:59.000Z

    A linear chain of connected electron sites with two asymmetric sinks, one attached to each end, is used as a simple model of quantum electron transfer in photosynthetic bio-complexes. For a symmetric initial population in the middle of the chain, it is expected that electron transfer is mainly directed towards the strongest coupled sink. However, we show that quantum effects radically change this intuitive "classical" mechanism, so that electron transfer can occur through the weaker coupled sink with maximal efficiency. Using this capability, we show how to design a quantum switch that can transfer an electron to the left or right branch of the chain, by changing the coupling to the sinks. The operational principles of this quantum device can be understood in terms of superradiance transitions and subradiant states. This switching, being a pure quantum effect, can be used as a witness of wave--like behaviour of excitations in molecular chains. When realistic data are used for the photosystem II reaction center, this quantum biological switch is shown to retain its reliability, even at room temperature.

  14. Dynamic control of catalysis within biological cells

    E-Print Network [OSTI]

    Biman Jana; Biman Bagchi

    2011-05-26T23:59:59.000Z

    We develop a theory of enzyme catalysis within biological cells where the substrate concentration [S](t) is time dependent, in contrast to the Michaelis-Menten theory that assumes a steady state. We find that the time varying concentration can combine, in a non-linear way, with the ruggedness of the free energy landscape of enzymes (discovered both in single molecule studies and in simulations) to provide a highly efficient switch (or, bifurcation) between two catalytically active states, at a critical substrate concentration. This allows a dynamic control of product synthesis in cell.

  15. X-ray holography of biological specimens

    SciTech Connect (OSTI)

    Solem, J.C.

    1984-01-01T23:59:59.000Z

    The author reviews the reasons for x-ray imaging of biological specimens and the techniques presently being used for x-ray microscopy. The author points out the advantages of x-ray holography and the difficulties of obtaining the requisite coherence with conventional sources. The author discusses the problems of radiation damage and the remarkable fact that short pulse x-ray sources circumvent these problems and obtain high-resolution images of specimens in the living state. Finally, the author reviews some of the efforts underway to develop high-intensity coherent x-ray sources for the laboratory. 14 references, 5 figures, 2 tables.

  16. Unraveling pancreatic islet biology by quantitative proteomics

    SciTech Connect (OSTI)

    Zhou, Jianying; Dann, Geoffrey P.; Liew, Chong W.; Smith, Richard D.; Kulkarni, Rohit N.; Qian, Weijun

    2011-08-01T23:59:59.000Z

    The pancreatic islets of Langerhans play a critical role in maintaining blood glucose homeostasis by secreting insulin and several other important peptide hormones. Impaired insulin secretion due to islet dysfunction is linked to the pathogenesis underlying both Type 1 and Type 2 diabetes. Over the past 5 years, emerging proteomic technologies have been applied to dissect the signaling pathways that regulate islet functions and gain an understanding of the mechanisms of islet dysfunction relevant to diabetes. Herein, we briefly review some of the recent quantitative proteomic studies involving pancreatic islets geared towards gaining a better understanding of islet biology relevant to metabolic diseases.

  17. 2007 Archaea: Ecology, Metabolism and Molecular Biology

    SciTech Connect (OSTI)

    Imke Schroeder

    2008-09-18T23:59:59.000Z

    The Archaea are a fascinating and diverse group of prokaryotic organisms with deep roots overlapping those of eukaryotes. The focus of this GRC conference, 'Archaea: Ecology Metabolism & Molecular Biology', expands on a number of emerging topics highlighting the evolution and composition of microbial communities and novel archaeal species, their impact on the environment, archaeal metabolism, and research that stems from sequence analysis of archaeal genomes. The strength of this conference lies in its ability to couple reputable areas with new scientific topics in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  18. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilAElectronic Input Options Garyand TechnicalAbout AboutWelcome to the Biological and

  19. Computational Biology | Supercomputing & Computation | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would like submit theInnovationComputational Biology SHARE Computational

  20. SC e-journals, Biology/Genetics

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItem Not Found Item Not Foundenhancer activity thanBiology/Genetics ACM Transactions on

  1. Biology and Soft Matter | Neutron Sciences | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041clothAdvanced Materials Advanced Materials Find Find More LikeAndreasHelp(SC) Biological

  2. Algal Biology Program at Los Alamos

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041cloth DocumentationProducts (VAP) VAP7-0973ManagedStrategic| NationalAlexanderAlgal Biology Program

  3. Biological Hydrogen Production Workshop | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the YouTube platform isEnergyMeeting | DepartmentBioenergyUS DepartmentBiological

  4. Deep Underground Science and Engineering Laboratory - Preliminary Design Report

    E-Print Network [OSTI]

    Kevin T. Lesko; Steven Acheson; Jose Alonso; Paul Bauer; Yuen-Dat Chan; William Chinowsky; Steve Dangermond; Jason A. Detwiler; Syd De Vries; Richard DiGennaro; Elizabeth Exter; Felix B. Fernandez; Elizabeth L. Freer; Murdock G. D. Gilchriese; Azriel Goldschmidt; Ben Grammann; William Griffing; Bill Harlan; Wick C. Haxton; Michael Headley; Jaret Heise; Zbigniew Hladysz; Dianna Jacobs; Michael Johnson; Richard Kadel; Robert Kaufman; Greg King; Robert Lanou; Alberto Lemut; Zoltan Ligeti; Steve Marks; Ryan D. Martin; John Matthesen; Brendan Matthew; Warren Matthews; Randall McConnell; William McElroy; Deborah Meyer; Margaret Norris; David Plate; Kem E. Robinson; William Roggenthen; Rohit Salve; Ben Sayler; John Scheetz; Jim Tarpinian; David Taylor; David Vardiman; Ron Wheeler; Joshua Willhite; James Yeck

    2011-08-03T23:59:59.000Z

    The DUSEL Project has produced the Preliminary Design of the Deep Underground Science and Engineering Laboratory (DUSEL) at the rehabilitated former Homestake mine in South Dakota. The Facility design calls for, on the surface, two new buildings - one a visitor and education center, the other an experiment assembly hall - and multiple repurposed existing buildings. To support underground research activities, the design includes two laboratory modules and additional spaces at a level 4,850 feet underground for physics, biology, engineering, and Earth science experiments. On the same level, the design includes a Department of Energy-shepherded Large Cavity supporting the Long Baseline Neutrino Experiment. At the 7,400-feet level, the design incorporates one laboratory module and additional spaces for physics and Earth science efforts. With input from some 25 science and engineering collaborations, the Project has designed critical experimental space and infrastructure needs, including space for a suite of multidisciplinary experiments in a laboratory whose projected life span is at least 30 years. From these experiments, a critical suite of experiments is outlined, whose construction will be funded along with the facility. The Facility design permits expansion and evolution, as may be driven by future science requirements, and enables participation by other agencies. The design leverages South Dakota's substantial investment in facility infrastructure, risk retirement, and operation of its Sanford Laboratory at Homestake. The Project is planning education and outreach programs, and has initiated efforts to establish regional partnerships with underserved populations - regional American Indian and rural populations.

  5. HST.071 Human Reproductive Biology, Fall 2002

    E-Print Network [OSTI]

    Klapholz, Henry

    Lectures and clinical case discussions designed to provide the student with a clear understanding of the physiology, endocrinology, and pathology of human reproduction. Emphasis is on the role of technology in reproductive ...

  6. Biologically inspired underwater propulsion and adhesion mechanisms

    E-Print Network [OSTI]

    Pan, Yichao

    2014-01-01T23:59:59.000Z

    The ultimate objective of this research is to develop an innovative underwater pipe inspection robot with both swimming and crawling capabilities as opposed to conventional in-pipe robots with wheeled designs or driven by ...

  7. Performance of biologically inspired flapping foils

    E-Print Network [OSTI]

    Read, Melissa B. (Melissa Beth), 1982-

    2006-01-01T23:59:59.000Z

    Flapping foil propulsion is thought to provide AUVs with greater maneuverability than propellers. This thesis seeks to simplify the design process for this type of propulsion system by identifying thrust and wake characteristics ...

  8. Rampressor Turbine Design

    SciTech Connect (OSTI)

    Ramgen Power Systems

    2003-09-30T23:59:59.000Z

    The design of a unique gas turbine engine is presented. The first Rampressor Turbine engine rig will be a configuration where the Rampressor rotor is integrated into an existing industrial gas turbine engine. The Rampressor rotor compresses air which is burned in a traditional stationary combustion system in order to increase the enthalpy of the compressed air. The combustion products are then expanded through a conventional gas turbine which provides both compressor and electrical power. This in turn produces shaft torque, which drives a generator to provide electricity. The design and the associated design process of such an engine are discussed in this report.

  9. Design of Vitrification Machine

    E-Print Network [OSTI]

    McDonald, Todd William

    2009-11-30T23:59:59.000Z

    ), and if it is capable of reliably and repeatedly controlling the Petri Dish Tray. These tests will serve to evaluate both the machine’s physical design as well as its software design. Along with the machine’s actual function, its overall design will be evaluated... the specimen is then moved through of series of Petri dishes containing cryo-protectant fluids, generally up to four (personal interview, Medical Advisor, Dr. Kim), using tweezers (alternatively, a pipette system may be employed). The technician must monitor...

  10. Passive solar design handbook

    SciTech Connect (OSTI)

    Jones, R.W.

    1981-01-01T23:59:59.000Z

    The Passive Solar Design Handbook, Volume Three updates Volume Two by presenting extensive new data on the optimum mix of conservation and solar direct gain, sunspaces, thermal storage walls, and solar radiation. The direct gain, thermal storage wall, and solar radiation data are greatly expanded relative to the Volume 2 coverage. The needed flexibility to analyze a variety of system designs is accommodated by the large number of reference designs to be encompassed - 94 in contrast to 6 in Volume two - and the large amount of sensitivity data for direct gain and sunspace systems - approximately 1100 separate curves.

  11. BIOLOGICAL AND MICROBIAL CONTROL Potential of Entomopathogenic Nematodes for Biological Control of

    E-Print Network [OSTI]

    nematodes, biological control, cucumber BLACK PLASTIC MULCH and drip or trickle irrigation). Drip irrigation, installed simulta- neously under the plastic mulch, uses less water than conventional is concentrated around the base of the plants (Orzolek et al. 1996). Used in combination, black plastic mulch

  12. Department of Chemical and Biological Engineering Department of Chemical and Biological Engineering

    E-Print Network [OSTI]

    Heller, Barbara

    Dynamics Lab Fuel Cell Lab Fuel Cell Battery Lab Fluidization Lab Gas Processing Lab Interfacial Phenomena: Energy and Sustainability Fuel Cells Fluidization and Gasification Hybrid Systems Biological Engineering Lab Process Control & Optimization Lab Process Modeling, Monitoring and Control Lab Rheology Lab Riser

  13. Biological and Environmental Research Network Requirements

    SciTech Connect (OSTI)

    Balaji, V. [Princeton Univ., NJ (United States). Earth Science Grid Federation (ESGF); Boden, Tom [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Cowley, Dave [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dart, Eli [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Dattoria, Vince [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Desai, Narayan [Argonne National Lab. (ANL), Argonne, IL (United States); Egan, Rob [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Foster, Ian [Argonne National Lab. (ANL), Argonne, IL (United States); Goldstone, Robin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gregurick, Susan [U.S. Dept. of Energy, Washington, DC (United States). Biological Systems Science Division; Houghton, John [U.S. Dept. of Energy, Washington, DC (United States). Biological and Environmental Research (BER) Program; Izaurralde, Cesar [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnston, Bill [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Joseph, Renu [U.S. Dept. of Energy, Washington, DC (United States). Climate and Environmental Sciences Division; Kleese-van Dam, Kerstin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lipton, Mary [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Monga, Inder [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Pritchard, Matt [British Atmospheric Data Centre (BADC), Oxon (United Kingdom); Rotman, Lauren [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Strand, Gary [National Center for Atmospheric Research (NCAR), Boulder, CO (United States); Stuart, Cory [Argonne National Lab. (ANL), Argonne, IL (United States); Tatusova, Tatiana [National Inst. of Health (NIH), Bethesda, MD (United States); Tierney, Brian [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). ESNet; Thomas, Brian [Univ. of California, Berkeley, CA (United States); Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Zurawski, Jason [Internet2, Washington, DC (United States)

    2013-09-01T23:59:59.000Z

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet be a highly successful enabler of scientific discovery for over 25 years. In November 2012, ESnet and the Office of Biological and Environmental Research (BER) of the DOE SC organized a review to characterize the networking requirements of the programs funded by the BER program office. Several key findings resulted from the review. Among them: 1) The scale of data sets available to science collaborations continues to increase exponentially. This has broad impact, both on the network and on the computational and storage systems connected to the network. 2) Many science collaborations require assistance to cope with the systems and network engineering challenges inherent in managing the rapid growth in data scale. 3) Several science domains operate distributed facilities that rely on high-performance networking for success. Key examples illustrated in this report include the Earth System Grid Federation (ESGF) and the Systems Biology Knowledgebase (KBase). This report expands on these points, and addresses others as well. The report contains a findings section as well as the text of the case studies discussed at the review.

  14. CREATIVE CONCEPTUAL DESIGN: EXTENDING THE SCOPE BY INFUSED DESIGN

    E-Print Network [OSTI]

    Shai, Offer

    1 CREATIVE CONCEPTUAL DESIGN: EXTENDING THE SCOPE BY INFUSED DESIGN Offer Shai School of Mechanical infused design that guarantees generating design solutions by transforming systems and methods from remote. This process is partially supported by a computer tool. We describe the method of infused design and illustrate

  15. Design of nanomanufacturing systems

    E-Print Network [OSTI]

    Slocum, Alexander Henry, Jr

    2010-01-01T23:59:59.000Z

    Over 100 years of manufacturing knowledge and experience are available to a design engineer when considering the integration of a machine tool enabling macro-scale processes (milling, turning, welding, water-jet cutting) ...

  16. Transformation inverse design

    E-Print Network [OSTI]

    Liu, David

    We present a new technique for the design of transformation-optics devices based on large-scale optimization to achieve the optimal effective isotropic dielectric materials within prescribed index bounds, which is ...

  17. ITER breeding blanket design

    SciTech Connect (OSTI)

    Gohar, Y.; Cardella, A.; Ioki, K.; Lousteau, D.; Mohri, K.; Raffray, R.; Zolti, E. [ITER Joint Central Team, Garching (Germany)] [and others

    1995-12-31T23:59:59.000Z

    A breeding blanket design has been developed for ITER to provide the necessary tritium fuel to achieve the technical objectives of the Enhanced Performance Phase. It uses a ceramic breeder and water coolant for compatibility with the ITER machine design of the Basic Performance Phase. Lithium zirconate and lithium oxide am the selected ceramic breeders based on the current data base. Enriched lithium and beryllium neutron multiplier are used for both breeders. Both forms of beryllium material, blocks and pebbles are used at different blanket locations based on thermo-mechanical considerations and beryllium thickness requirements. Type 316LN austenitic steel is used as structural material similar to the shielding blanket. Design issues and required R&D data are identified during the development of the design.

  18. Relationships in design build

    E-Print Network [OSTI]

    Wampler, Charles Wilson

    2010-01-01T23:59:59.000Z

    As design build (DB) becomes more popular, different ways of writing contracts and forming relationships with the various parties are being considered. The main point of this paper is to look at the relationships between ...

  19. Alternative energy design toolkit

    E-Print Network [OSTI]

    Sukkasi, Sittha

    2004-01-01T23:59:59.000Z

    This thesis concerns the concepts, structure, and applications of the Alternative Energy Design Toolkit. The toolkit is aimed to provide a widely accessible, easy to use, flexible, yet powerful modeling environment for ...

  20. Expert assistants for design

    SciTech Connect (OSTI)

    Aldridge, J.; Cerutti, J.; Draisin, W.; Steuerwalt, M.

    1986-01-01T23:59:59.000Z

    Two expert programs currently under development at the Los Alamos National Laboratory, PROCON and the Designer's Apprentice, are briefly described. Both codes define interface to simulations that provide a wide variety of information about the performance of complex devices. (BCS)

  1. Cogeneration System Design Options

    E-Print Network [OSTI]

    Gilbert, J. S.

    The commercial or industrial firm contemplating cogeneration at its facilities faces numerous basic design choices. The possibilities exist for fueling the system with waste materials, gas, oil, coal, or other combustibles. The choice of boiler...

  2. Extraction Utility Design Specification

    Energy Savers [EERE]

    Extraction Utility Design Specification January 11, 2011 Document Version 1.9 1 Revision History Date Version Section and Titles Author Summary of Change January 15, 2010 1.0 All...

  3. Advanced Energy Design Guides

    Energy Savers [EERE]

    hotels up to 80 rooms and 4 stories Advanced Energy Design Guide for Small Hospitals and Health- care Facilities ASHE, ASHRAE, AIA, IES, USGBC, DOE Small healthcare facilities up...

  4. Transmission line: design manual

    SciTech Connect (OSTI)

    Farr, H.H.

    1980-01-01T23:59:59.000Z

    The purpose of this manual is to outline the various requirements for, and the procedures to be followed in the design of power transmission lines by the Bureau of Reclamation, US Department of the Interior. Numerous design studies, which have been made on specific aspects of transmission line design, are included with explanations of their applications. Information is presented concerning such aspects as selection of type of construction, conductor sags and tensions, insulation, lightning protection, clearance patterns, galloping conductors, structure limitation and guying charts, and structure spotting. Structure design examples are limited to wood-pole construction. Interpretations of the National Electrical Safety Code and other codes are made as required. Some of the example problems were developed when the sixth edition of NESC was current, and are so noted; however, most examples use the 1977 edition of NESC.

  5. C H A P T E R F O U R T E E N Microfluidics for Synthetic Biology

    E-Print Network [OSTI]

    Hasty, Jeff

    C H A P T E R F O U R T E E N Microfluidics for Synthetic Biology: From Design to Execution M. S of a microfluidic chip 298 1.2. A parallel DAW device 322 1.3. Cell tracking 326 1.4. DAW hardware and software 334. coli 358 3.2. Method to set up a MDAW microfluidic experiment 364 Acknowledgments 371 References 371

  6. Comparing object oriented and traditional designs for a forest pest management decision support system

    E-Print Network [OSTI]

    Power, J. M

    1991-01-01T23:59:59.000Z

    developed for a forest pest management decision support system (DSS) to simulate the pattern of functional reusability during system evolution. Each design model was constructed using the Nexpert Object expert system development shell. The 00 design used... CONTROL PLAN PEST SURVEY ES POPULATION DBMS PIANT SPATIAL ANIMAL INSEC'I POPULATION COMPUTER LIFE STAGE PLANT POPULATION~ TOP~ BIOLOGICAL SIMULATION~ WEATHER TREE PHYSICAL~~ SOIL MANAGEMENT FIRE SPATIAL QUERY SUITABILITY QUERY SIMULATION QUERY...

  7. Functionalized apertures for the detection of chemical and biological materials

    DOE Patents [OSTI]

    Letant, Sonia E. (Livermore, CA); van Buuren, Anthony W. (Livermore, CA); Terminello, Louis J. (Danville, CA); Thelen, Michael P. (Danville, CA); Hope-Weeks, Louisa J. (Brentwood, CA); Hart, Bradley R. (Brentwood, CA)

    2010-12-14T23:59:59.000Z

    Disclosed are nanometer to micron scale functionalized apertures constructed on a substrate made of glass, carbon, semiconductors or polymeric materials that allow for the real time detection of biological materials or chemical moieties. Many apertures can exist on one substrate allowing for the simultaneous detection of numerous chemical and biological molecules. One embodiment features a macrocyclic ring attached to cross-linkers, wherein the macrocyclic ring has a biological or chemical probe extending through the aperture. Another embodiment achieves functionalization by attaching chemical or biological anchors directly to the walls of the apertures via cross-linkers.

  8. anaerobic biological reactors: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Peter R. 97 Department of Agricultural and Biological Engineering Fall 2011 Small Scale Anaerobic Digestion by PENERGY Solutions Materials Science Websites Summary: with less...

  9. aerobic biological treatment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    L. Rezende; Kimberly A. Hammond 2003-01-01 17 Factors influencing biological treatment of MTBE contaminated ground water University of California eScholarship Repository Summary:...

  10. Biological Conversion of Sugars to Hydrocarbons Technology Pathway

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    case investigates the biological conversion of biomass-derived sugars to hydrocarbon biofuels, utilizing data from recent literature references and information consistent with...

  11. Bridging from Cells to Cognition in Autism Pathophysiology: Biological...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    from Cells to Cognition in Autism Pathophysiology: Biological Pathways to Defective Brain Function and Plasticity. Bridging from Cells to Cognition in Autism Pathophysiology:...

  12. Molecular biology of signal transduction in plants. Abstracts

    SciTech Connect (OSTI)

    Not Available

    1991-12-31T23:59:59.000Z

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  13. September 2013 Most Viewed Documents for Biology And Medicine...

    Office of Scientific and Technical Information (OSTI)

    September 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Drug Retention Times Center for Human Reliability Studies (2007) 29 > Oleoresin Capsicum...

  14. aquaculture biological agent: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Invertebrates Summer C, 2013 Environmental Sciences and Ecology Websites Summary: SYLLABUS Biology of Fisheries and Aquaculture Invertebrates FAS 6932 Summer C, 2013 Instructor...

  15. aquaculture overcoming biological: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Invertebrates Summer C, 2013 Environmental Sciences and Ecology Websites Summary: SYLLABUS Biology of Fisheries and Aquaculture Invertebrates FAS 6932 Summer C, 2013 Instructor...

  16. ancient biological invasion: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    who has published in the areas of invasion Davis, Mark A. 4 1 Invasion Ecology syllabus, spring 2012 Description: Mechanisms and hypotheses to explain biological invasions....

  17. Selection of bioclimatically representative biological reserve systems under climate change

    E-Print Network [OSTI]

    Pyke, C R; Fischer, Douglas T

    2005-01-01T23:59:59.000Z

    of bioclimatically representative biological reserve systemsthat are bioclimatically representative across a range ofa ?at line (i.e. a representative sample of current climate

  18. Dissecting Cell Signaling Using Synthetic Biology: New Methods...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dissecting Cell Signaling Using Synthetic Biology: New Methods for Engineered Control of Protein Kinases and Phosphatases Event Sponsor: Argonne Leadership Computing Facility...

  19. DOE Issues Request for Information on Biological Hydrogen Production...

    Broader source: Energy.gov (indexed) [DOE]

    (RFI) seeking feedback from interested stakeholders regarding biological hydrogen production research and development (R&D) pathways, barriers, issues, and opportunities for...

  20. adversely impacts biological: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    proposed Federal action evaluate the impacts of the action with respect to the human environment, including its biological, economic, and social components. This chapter addresses...

  1. Biological Conversion of Sugars to Hydrocarbons Technology Pathway...

    Broader source: Energy.gov (indexed) [DOE]

    for the pathway to become competitive with petroleum-derived gasoline-, diesel-, and jet-range hydrocarbon blendstocks. Biological Conversion of Sugars to Hydrocarbons...

  2. Structural and biological studies of bone morphogenetic protein-15

    E-Print Network [OSTI]

    McMahon, Heather Eileen

    2007-01-01T23:59:59.000Z

    homolog, GDF-9; both proteins lack the fourth of seventhe recombinant protein with this mutation lacks biologicallacks biological activity and, intriguingly, the mutant protein

  3. Genomics and Systems Biology of Tuberculosis (2009 JGI User Meeting)

    ScienceCinema (OSTI)

    Galagan, James

    2011-04-25T23:59:59.000Z

    James Galagan from the Broad Institute spoke about the "Genomics and Systems Biology of TB" on March 26, 2009 during the 4th Annual User Meeting

  4. March 2014 Most Viewed Documents for Biology And Medicine | OSTI...

    Office of Scientific and Technical Information (OSTI)

    March 2014 Most Viewed Documents for Biology And Medicine Science Subject Feed Carbon Dioxide Sequestering Using Microalgal Systems Daniel J. Stepan; Richard E. Shockey; Thomas A....

  5. Extinction cascade: Biological consequence of nuclear war/winter

    SciTech Connect (OSTI)

    Vaughan, G.L.; Pimm, S.; Fields, D.E.

    1987-01-01T23:59:59.000Z

    In very general terms, this report describes the effects on biological organisms of a nuclear war and the projected nuclear winter that would follow. (TEM)

  6. A stochastic model dissects cell states in biological transition processes

    E-Print Network [OSTI]

    Armond, Jonathan W.

    Many biological processes, including differentiation, reprogramming, and disease transformations, involve transitions of cells through distinct states. Direct, unbiased investigation of cell states and their transitions ...

  7. March 2015 Most Viewed Documents for Biology And Medicine | OSTI...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    March 2015 Most Viewed Documents for Biology And Medicine Measuring dopamine release in the human brain with PET Volkow, N.D. Brookhaven National Lab., Upton, NY (United...

  8. Biologically engineering nanostructures to maximize energy, electron, and ion transport

    E-Print Network [OSTI]

    Park, Heechul

    2014-01-01T23:59:59.000Z

    Human intellectual desire inspires recent research to expand to interdisciplinary areas across biology, chemistry, and physics. Interdisciplinary research in unexplored areas is challenging, but holds great promise to ...

  9. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production

    SciTech Connect (OSTI)

    James, B. D.; Baum, G. N.; Perez, J.; Baum, K. N.

    2009-09-01T23:59:59.000Z

    Report documenting the biological and engineering characteristics of five algal and bacterial hydrogen production systems selected by DOE and NREL for evaluation.

  10. ANAEROBIC BIOLOGICAL TREATMENT OF PRODUCED WATER

    SciTech Connect (OSTI)

    John R. Gallagher

    2001-07-31T23:59:59.000Z

    During the production of oil and gas, large amounts of water are brought to the surface and must be disposed of in an environmentally sensitive manner. This is an especially difficult problem in offshore production facilities where space is a major constraint. The chief regulatory criterion for produced water is oil and grease. Most facilities have little trouble meeting this criterion using conventional oil-water separation technologies. However, some operations have significant amounts of naphthenic acids in the water that behave as oil and grease but are not well removed by conventional technologies. Aerobic biological treatment of naphthenic acids in simulated-produced water has been demonstrated by others; however, the system was easily overloaded by the large amounts of low-molecular-weight organic acids often found in produced waters. The objective of this research was to determine the ability of an anaerobic biological system to treat these organic acids in a simulated produced water and to examine the potential for biodegradation of the naphthenic acids in the anaerobic environment. A small fixed-film anaerobic biological reactor was constructed and adapted to treat a simulated produced water. The bioreactor was tubular, with a low-density porous glass packing material. The inocula to the reactor was sediment from a produced-water holding pond from a municipal anaerobic digester and two salt-loving methanogenic bacteria. During start-up, the feed to the reactor contained glucose as well as typical produced-water components. When glucose was used, rapid gas production was observed. However, when glucose was eliminated and the major organic component was acetate, little gas was generated. Methane production from acetate may have been inhibited by the high salt concentrations, by sulfide, or because of the lack, despite seeding, of microbes capable of converting acetate to methane. Toluene, a minor component of the produced water (0.1 g/L) was removed in the reactor. Batch tests were conducted to examine naphthenic acid biodegradability under several conditions. The conditions used were seed from the anaerobic reactor, wetland sediments under aerobic and anaerobic conditions, and a sterile control. The naphthenic acid was from a commercial source isolated from Gulf Coast petroleum as was dosed at 2 mg/mL. The incubations were for 30 days at 30 C. The results showed that the naphthenic acids were not biodegraded under anaerobic conditions, but were degraded under aerobic conditions. Despite poor performance of the anaerobic reactor, it remains likely that anaerobic treatment of acetate, toluene, and, potentially, other produced-water components is feasible.

  11. Green Buildings: Construction Design Firms' Implementation of Sustainable Design Standards

    E-Print Network [OSTI]

    Malone, Nathan

    2008-12-19T23:59:59.000Z

    This paper is written to show the importance of green buildings and therefore the need for sustainable design. The paper describes why a construction design firm must take the steps necessary to properly integrate these sustainable design standards...

  12. Design Space Exploration of Parameterized Systems using Design of Experiments

    E-Print Network [OSTI]

    Sheldon, David

    2011-01-01T23:59:59.000Z

    13 2.1 Design space exploration for system specific tuningShin Figure 5: Noxim NoC design space with over 60,00030: Percent of the design space that needs to be explored in

  13. Metallurgical Process Design A tribute to Douglas' conceptual design approach

    E-Print Network [OSTI]

    Linninger, Andreas A.

    and systematic flowsheet generation1-2. . Although perfected for continuous petrochemical processes, this work1 Metallurgical Process Design ­ A tribute to Douglas' conceptual design approach Andreas A. Linninger Laboratory for Product and Process Design Department of Chemical Engineering, University

  14. MSENGR Product Design Program Proposal

    E-Print Network [OSTI]

    Prinz, Friedrich B.

    MSENGR Product Design Program Proposal Rev 6/2007 p. 1 New Proposal Revision First graduate Language 3 ME216A Advanced Product Design: Need Finding 4 ME312 Advanced Product Design: Form Giving 4 ARTSTUDI160 Design II: The Bridge 3 ME216B Advanced Product Design: Implementation 4 ME316

  15. Interaction of biological systems with static and ELF electric and magnetic fields

    SciTech Connect (OSTI)

    Anderson, L.E.; Kelman, B.J.; Weigel, R.J. (eds.)

    1987-01-01T23:59:59.000Z

    Although background levels of atmospheric electric and geomagnetic field levels are extremely low, over the past several decades, human beings and other life forms on this planet have been subjected to a dramatically changing electromagnetic milieu. An exponential increase in exposure to electromagnetic fields has occurred, largely because of such technological advances as the growth of electrical power generation and transmission systems, the increased use of wireless communications, and the use of radar. In addition, electromagnetic field generating devices have proliferated in industrial plants, office buildings, homes, public transportation systems, and elsewhere. Although significant increases have occurred in electromagnetic field strenghths spanning all frequency ranges, this symposium addresses only the impact of these fields at static and extremely low frequencies (ELF), primarily 50 and 60 Hz. This volume contains the proceedings of the symposium entitled /open quotes/Interaction of biological systems with static and ELF electric and magnetic fields/close quotes/. The purpose of the symposium was to provide a forum for discussions of all aspects of research on the interaction of static and ELF electromagnetic fields with biological systems. These systems include simple biophysical models, cell and organ preparations, whole animals, and man. Dosimetry, exposure system design, and artifacts in ELF bioeffects research were also addressed, along with current investigations that examine fundamental mechanisms of interactions between the fields and biological processes. Papers are indexed separately.

  16. Oak Ridge Y-12 Plant biological monitoring and abatement program (BMAP) plan

    SciTech Connect (OSTI)

    Adams, S.M.; Brandt, C.C.; Cicerone, D.S. [and others

    1998-02-01T23:59:59.000Z

    The proposed Biological Monitoring and Abatement Program (BMAP) for East Fork Poplar Creek (EFPC) at the Oak Ridge Y-12 Plant, as described, will be conducted for the duration of the National Pollutant Discharge Elimination System permit issued for the Y-12 Plant on April 28, 1995, and which became effective July 1, 1995. The basic approach to biological monitoring used in this program was developed by the staff in the Environmental Sciences Division at the Oak Ridge National Laboratory at the request of Y-12 Plant personnel. The proposed BMAP plan is based on results of biological monitoring conducted since 1985. Details of the specific procedures used in the current routine monitoring program are provided, but experimental designs for future studies are described in less detail. The overall strategy used in developing this plan was, and continues to be, to use the results obtained from each task to define the scope of future monitoring efforts. Such efforts may require more intensive sampling than initially proposed in some areas or a reduction in sampling intensity in others. By using the results of previous monitoring efforts to define the current program and to guide them in the development of future studies, an effective integrated monitoring program has been developed to assess the impacts of the Y-12 Plant operation on the biota of EFPC and to document the ecological effects of remedial actions.

  17. Protecting buildings from a biological or chemical attack: Actions to take before or during a release

    SciTech Connect (OSTI)

    Price, Phillip N.; Sohn, Michael D.; Gadgil, Ashok J.; Delp, William W.; Lorenzetti, David M.; Finlayson, Elizabeth U.; Thatcher, Tracy L.; Sextro, Richard G.; Derby, Elisabeth A.; Jarvis, Sondra A.

    2003-01-29T23:59:59.000Z

    This report presents advice on how to operate a building to reduce casualties from a biological or chemical attack, as well as potential changes to the building (e.g. the design of the ventilation system) that could make it more secure. It also documents the assumptions and reasoning behind the advice. The particular circumstances of any attack, such as the ventilation system design, building occupancy, agent type, source strength and location, and so on, may differ from the assumptions made here, in which case actions other than our recommendations may be required; we hope that by understanding the rationale behind the advice, building operators can modify it as required for their circumstances. The advice was prepared by members of the Airflow and Pollutant Transport Group, which is part of the Indoor Environment Department at the Lawrence Berkeley National Laboratory. The group's expertise in this area includes: tracer-gas measurements of airflows in buildings (Sextro, Thatcher); design and operation of commercial building ventilation systems (Delp); modeling and analysis of airflow and tracer gas transport in large indoor spaces (Finlayson, Gadgil, Price); modeling of gas releases in multi-zone buildings (Sohn, Lorenzetti, Finlayson, Sextro); and occupational health and safety experience related to building design and operation (Sextro, Delp). This report is concerned only with building design and operation; it is not a how-to manual for emergency response. Many important emergency response topics are not covered here, including crowd control, medical treatment, evidence gathering, decontamination methods, and rescue gear.

  18. Design-optimization and material selection for a femoral-fracture fixation-plate implant

    E-Print Network [OSTI]

    Grujicic, Mica

    July 2009 Accepted 20 January 2010 Available online 25 January 2010 Keywords: Musculoskeletal modeling-element/design-optimization procedure. To obtain realistic physio- logical loading conditions associated with normal living activities fixation devices is attributed to biological factors such as extensive soft-tissue traumatic injury

  19. Computer-Aided Design for Microfluidic Chips Based on Multilayer Soft Lithography

    E-Print Network [OSTI]

    Rajamani, Sriram K.

    Computer-Aided Design for Microfluidic Chips Based on Multilayer Soft Lithography Nada Amin1 Abstract-- Microfluidic chips are emerging as a powerful platform for automating biology experiments automation techniques for microfluidic chips based on multilayer soft lithography. We focus our attention

  20. Designing fecal pellet surveys for snowshoe hares K.E. Hodges *, L.S. Mills

    E-Print Network [OSTI]

    Mills, L. Scott

    Designing fecal pellet surveys for snowshoe hares K.E. Hodges *, L.S. Mills Wildlife Biology, 2003), some popular indices, like counts of fecal pellets, have been used to answer basic ecological pellets to examine long-term population dynamics at individual sites (Malloy, 2000; Krebs et al., 2001