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Sample records for biological assessment cape

  1. California Valley Solar Ranch Biological Assessment

    Broader source: Energy.gov [DOE]

    Biological Assessment for the California Valley Solar Ranch Project San Luis Obispo County, California

  2. Computational Tools to Assess Turbine Biological Performance

    SciTech Connect (OSTI)

    Richmond, Marshall C.; Serkowski, John A.; Rakowski, Cynthia L.; Strickler, Brad; Weisbeck, Molly; Dotson, Curtis L.

    2014-07-24

    Public Utility District No. 2 of Grant County (GCPUD) operates the Priest Rapids Dam (PRD), a hydroelectric facility on the Columbia River in Washington State. The dam contains 10 Kaplan-type turbine units that are now more than 50 years old. Plans are underway to refit these aging turbines with new runners. The Columbia River at PRD is a migratory pathway for several species of juvenile and adult salmonids, so passage of fish through the dam is a major consideration when upgrading the turbines. In this paper, a method for turbine biological performance assessment (BioPA) is demonstrated. Using this method, a suite of biological performance indicators is computed based on simulated data from a CFD model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. Using known relationships between the dose of an injury mechanism and frequency of injury (dose–response) from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from proposed designs, the engineer can identify the more-promising alternatives. We present an application of the BioPA method for baseline risk assessment calculations for the existing Kaplan turbines at PRD that will be used as the minimum biological performance that a proposed new design must achieve.

  3. Assessment of primary production and optical variability in shelf and slope waters near Cape Hatteras, North Carolina. Final project report

    SciTech Connect (OSTI)

    Redalje, Donald G.; Lohrenz, Stevern E.

    2001-02-12

    In this project we determined primary production and optical variability in the shelf and slope waters off of Cape Hatteras, N.C. These processes were addressed in conjunction with other Ocean Margins Program investigators, during the Spring Transition period and during Summer. We found that there were significant differences in measured parameters between Spring and Summer, enabling us to develop seasonally specific carbon production and ecosystem models as well as seasonal and regional algorithm improvements for use in remote sensing applications.

  4. Cape Wind Project | Open Energy Information

    Open Energy Info (EERE)

    Project Jump to: navigation, search Name Cape Wind Project Facility Cape Wind Sector Wind energy Facility Type Offshore wind Facility Status Proposed Owner Cape Wind Developer Cape...

  5. PG&E Reconductoring Project Biological Assessment (Revised)

    Broader source: Energy.gov [DOE]

    This biological assessment (BA) is to provide the information necessary for formal consultation between the Department of Energy (DOE) and U.S. Fish and Wildlife Service (USFWS) regarding the effects of the Proposed Action as required pursuant to Section 7(a)(2) of the Endangered Species Act (ESA).

  6. Grays River Watershed and Biological Assessment Final Report 2006.

    SciTech Connect (OSTI)

    May, Christopher W.; McGrath, Kathleen E.; Geist, David R.; Abbe, Timothy; Barton, Chase

    2008-02-04

    The Grays River Watershed and Biological Assessment was funded to address degradation and loss of spawning habitat for chum salmon (Onchorhynchus keta) and fall Chinook salmon (Onchoryhnchus tshawytscha). In 1999, the National Marine Fisheries Service listed lower Columbia River chum salmon as a threatened Evolutionarily Significant Unit (ESU) under the Endangered Species Act of 1973 (ESA). The Grays River watershed is one of two remaining significant chum salmon spawning locations in this ESU. Runs of Grays River chum and Chinook salmon have declined significantly during the past century, largely because of damage to spawning habitat associated with timber harvest and agriculture in the watershed. In addition, approximately 20-25% of the then-remaining chum salmon spawning habitat was lost during a 1999 channel avulsion that destroyed an important artificial spawning channel operated by the Washington Department of Fish and Wildlife (WDFW). Although the lack of stable, high-quality spawning habitat is considered the primary physical limitation on Grays River chum salmon production today, few data are available to guide watershed management and channel restoration activities. The objectives of the Grays River Watershed and Biological Assessment project were to (1) perform a comprehensive watershed and biological analysis, including hydrologic, geomorphic, and ecological assessments; (2) develop a prioritized list of actions that protect and restore critical chum and Chinook salmon spawning habitat in the Grays River based on comprehensive geomorphic, hydrologic, and stream channel assessments; and (3) gain a better understanding of chum and Chinook salmon habitat requirements and survival within the lower Columbia River and the Grays River. The watershed-based approach to river ecosystem restoration relies on a conceptual framework that describes general relationships between natural landscape characteristics, watershed-scale habitat-forming processes, aquatic habitat conditions, and biological integrity. In addition, human land-use impacts are factored into the conceptual model because they can alter habitat quality and can disrupt natural habitat-forming processes. In this model (Figure S.1), aquatic habitat--both instream and riparian--is viewed as the link between watershed conditions and biologic responses. Based on this conceptual model, assessment of habitat loss and the resultant declines in salmonid populations can be conducted by relating current and historical (e.g., natural) habitat conditions to salmonid utilization, diversity, and abundance. In addition, assessing disrupted ecosystem functions and processes within the watershed can aid in identifying the causes of habitat change and the associated decline in biological integrity. In this same way, restoration, enhancement, and conservation projects can be identified and prioritized. A watershed assessment is primarily a landscape-scale evaluation of current watershed conditions and the associated hydrogeomorphic riverine processes. The watershed assessment conducted for this project focused on watershed processes that form and maintain salmonid habitat. Landscape metrics describing the level of human alteration of natural ecosystem attributes were used as indicators of water quality, hydrology, channel geomorphology, instream habitat, and biotic integrity. Ecological (watershed) processes are related to and can be predicted based on specific aspects of spatial pattern. This study evaluated the hydrologic regime, sediment delivery regime, and riparian condition of the sub-watersheds that comprise the upper Grays River watershed relative to their natural range of conditions. Analyses relied primarily on available geographic information system (GIS) data describing landscape characteristics such as climate, vegetation type and maturity, geology and soils, topography, land use, and road density. In addition to watershed-scale landscape characteristics, the study area was also evaluated on the riparian scale, with appropriate landscape variables analyzed within

  7. University of Cape Town | Open Energy Information

    Open Energy Info (EERE)

    to: navigation, search Name: University of Cape Town Place: South Africa Product: Teaching and research university. References: University of Cape Town1 This article is a...

  8. ARM - News from the Cape Cod Deployment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    News from the Cape Cod Deployment Media Coverage WCAI (public radio) "Cape-based Project Aims to Strengthen Climate Models" March 19, 2013 Wicked Local "Truro is ground...

  9. Grays River Watershed and Biological Assessment, 2006 Final Report.

    SciTech Connect (OSTI)

    May, Christopher; Geist, David

    2007-04-01

    The Grays River Watershed and Biological Assessment was funded to address degradation and loss of spawning habitat for chum salmon (Onchorhynchus keta) and fall Chinook salmon (Onchoryhnchus tshawytscha). In 1999, the National Marine Fisheries Service listed lower Columbia River chum salmon as a threatened Evolutionarily Significant Unit (ESU) under the Endangered Species Act of 1973 (ESA). The Grays River watershed is one of two remaining significant chum salmon spawning locations in this ESU. Runs of Grays River chum and Chinook salmon have declined significantly during the past century, largely because of damage to spawning habitat associated with timber harvest and agriculture in the watershed. In addition, approximately 20-25% of the then-remaining chum salmon spawning habitat was lost during a 1999 channel avulsion that destroyed an important artificial spawning channel operated by the Washington Department of Fish and Wildlife (WDFW). Although the lack of stable, high-quality spawning habitat is considered the primary physical limitation on Grays River chum salmon production today, few data are available to guide watershed management and channel restoration activities. The objectives of the Grays River Watershed and Biological Assessment project were to (1) perform a comprehensive watershed and biological analysis, including hydrologic, geomorphic, and ecological assessments; (2) develop a prioritized list of actions that protect and restore critical chum and Chinook salmon spawning habitat in the Grays River based on comprehensive geomorphic, hydrologic, and stream channel assessments; and (3) gain a better understanding of chum and Chinook salmon habitat requirements and survival within the lower Columbia River and the Grays River. The watershed-based approach to river ecosystem restoration relies on a conceptual framework that describes general relationships between natural landscape characteristics, watershed-scale habitat-forming processes, aquatic habitat conditions, and biological integrity. In addition, human land-use impacts are factored into the conceptual model because they can alter habitat quality and can disrupt natural habitat forming processes. In this model (Figure S.1), aquatic habitat--both instream and riparian--is viewed as the link between watershed conditions and biologic responses. Based on this conceptual model, assessment of habitat loss and the resultant declines in salmonid populations can be conducted by relating current and historical (e.g., natural) habitat conditions to salmonid utilization, diversity, and abundance. In addition, assessing disrupted ecosystem functions and processes within the watershed can aid in identifying the causes of habitat change and the associated decline in biological integrity. In this same way, restoration, enhancement, and conservation projects can be identified and prioritized. A watershed assessment is primarily a landscape-scale evaluation of current watershed conditions and the associated hydrogeomorphic riverine processes. The watershed assessment conducted for this project focused on watershed processes that form and maintain salmonid habitat. Landscape metrics describing the level of human alteration of natural ecosystem attributes were used as indicators of water quality, hydrology, channel geomorphology, instream habitat, and biotic integrity. Ecological (watershed) processes are related to and can be predicted based on specific aspects of spatial pattern. This study evaluated the hydrologic regime, sediment delivery regime, and riparian condition of the sub-watersheds that comprise the upper Grays River watershed relative to their natural range of conditions. Analyses relied primarily on available geographic information system (GIS) data describing landscape characteristics such as climate, vegetation type and maturity, geology and soils, topography, land use, and road density. In addition to watershed-scale landscape characteristics, the study area was also evaluated on the riparian scale, with appropriate landscape variables analyzed within riparian buffers around each stream or river channel. Included in the overall watershed assessment are field habitat surveys and analyses of the physical and hydrological characteristics of primary chum and fall Chinook salmon spawning areas and spawning habitat availability and use. This assessment is a significant step in a comprehensive program to ensure the survival and recovery of Columbia River chum salmon in its most productive system and builds on existing recovery planning efforts for these ESA-listed salmonids within the Grays River and the lower Columbia River. This assessment also provides a basis for the recovery of other fish species in the Grays River, including coho salmon, winter steelhead, coastal cutthroat trout, and Pacific lamprey.

  10. EIS-0470: Cape Wind Energy Project, Nantucket Sound, Offshore...

    Energy Savers [EERE]

    0: Cape Wind Energy Project, Nantucket Sound, Offshore of Massachusetts EIS-0470: Cape Wind Energy Project, Nantucket Sound, Offshore of Massachusetts June 25, 2014 EIS-0470: Cape ...

  11. Methods for isolation and viability assessment of biological organisms

    DOE Patents [OSTI]

    Letant, Sonia Edith; Baker, Sarah Elyse; Bond, Tiziana; Chang, Allan Shih-Ping

    2015-02-03

    Isolation of biological or chemical organisms can be accomplished using a surface enhanced Raman scattering (SERS) system. The SERS system can be a single or a stacked plurality of photonic crystal membranes with noble-metal lined through pores for flowing analyte potentially containing the biological or chemical organisms. The through pores can be adapted to trap individual biological or chemical organisms and emit SERS spectra, which can then be detected by a detector and further analyzed for viability of the biological or chemical organism.

  12. ARM Convective Available Potential Energy (CAPE), Convective...

    Office of Scientific and Technical Information (OSTI)

    Country of Publication: United States Availability: ORNL Language: English Subject: 54 Environmental Sciences ARMBE, Soundings; Convective Available Potential Energy (CAPE); ...

  13. Hydro Review: Computational Tools to Assess Turbine Biological Performance

    Broader source: Energy.gov [DOE]

    This review covers the BioPA method used to analyze the biological performance of proposed designs to help ensure the safety of fish passing through the turbines at the Priest Rapids Dam in Grant County, Washington.

  14. Biological assessments for the low energy demonstration accelerator, 1996

    SciTech Connect (OSTI)

    Cross, S.

    1997-03-01

    This report discusses the biological impact to the area around the Los Alamos National Laboratory of the Low Energy Demonstration Accelerator. In particular the impact to the soils, water quality, vegetation, and wildlife are discussed.

  15. Proliferation profile assessment of emerging biological weapons threats. Research paper

    SciTech Connect (OSTI)

    Archuleta, M.G.; Bland, M.S.; Duann, T.P.; Tucker, A.B.

    1996-04-01

    This project develops a first generation biological warfare (BW) program system model for use in the DOD`s counterproliferation workstation, identifies key issues the U.S. military must address to assure its forces are prepared to fight in a BW environment, and develops a concise BW primer for use by any DOD activity requiring such information. The greatest lesson to be learned from this study is that only through the collective analysis of all the sub-systems of a suspected BW program will conclusive evidence of the program be found. Still, with current counterproliferation capabilities the U.S. may only be able to slow, not stop a motivated proliferant.

  16. Cape Systems Limited | Open Energy Information

    Open Energy Info (EERE)

    Limited Jump to: navigation, search Name: Cape Systems Limited Place: Rock Sound, Bahamas Sector: Services Product: Offers installation and site surveying services for clean...

  17. Cape Verde Capital | Open Energy Information

    Open Energy Info (EERE)

    Capital Jump to: navigation, search Name: Cape Verde Capital Place: Leatherhead, United Kingdom Zip: KT22 7SW Sector: Renewable Energy Product: The renewable energy investment arm...

  18. B I OENV I RONMENTAL FEATURES OF THE OGOTORUK CREEK AREA, CAPE THOMPSON, ALASKA

    Office of Legacy Management (LM)

    B I OENV I RONMENTAL FEATURES OF THE OGOTORUK CREEK AREA, CAPE THOMPSON, ALASKA A First Summary by The Committee on Environmental Studies for Project Chariot . . December 1960 r Division of Biology and Medicine, AEC Washington, D. C. IT U S WEGWS LIBIA3"b This page intentionally left blank NUCLEAR EXPLOSIONS -PEACE UL APPLICATIONS . . BIOLOGY AND MEDICINE BIOENVIRONMENTAL FEATURES OF THE OGOTORUK CREEK AREA . . CAPE THOMPSON, ALASKA A F i r s t Sumnary The C o d t t e e on E n v i r o n m e

  19. Cape Cod Regional Transit Authority | Open Energy Information

    Open Energy Info (EERE)

    Cod Regional Transit Authority Jump to: navigation, search Name Cape Cod Regional Transit Authority Facility Cape Cod Regional Transit Authority Sector Wind energy Facility Type...

  20. DOE Offers Conditional Commitment to Cape Wind Offshore Wind...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Offers Conditional Commitment to Cape Wind Offshore Wind Generation Project DOE Offers Conditional Commitment to Cape Wind Offshore Wind Generation Project September 11, 2014 - ...

  1. Energy Department Offers Conditional Commitment to Cape Wind...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cape Wind Offshore Wind Generation Project Energy Department Offers Conditional Commitment to Cape Wind Offshore Wind Generation Project July 1, 2014 - 9:23am Addthis News Media ...

  2. Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology @WIPP Life Begins at 250,000,000 Years WIPP's underground isn't just suited for physics experiments aiming to unlock the mysteries of the Universe, it is also a perfect...

  3. Strategies for Assessment of the Biological Performance and Design of Hydroturbines

    SciTech Connect (OSTI)

    Carlson, Thomas J.; Richmond, Marshall C.

    2011-05-05

    The biological response of fish to turbine passage has been of concern for several decades and emphasized recently by consideration of hydro as a 'green' power source. The current state-of-the-art of hydro-turbine biological performance assessment, while still inadequate, has advanced considerably the past 10 years. For example, the importance of assessment of exposure to pressure changes during turbine passage has been emphasized by findings of laboratory studies of rapid decompression. It is now very clear that hydroturbine biological assessment must consider the physiological state and behavior of fish at turbine entry and changes in physiological state that drive aspects of behavior during tailrace passage. Such considerations are in addition to concerns about exposure of fish to mechanical and pressure sources of injury during turbine passage. Experimental designs and assessment tools have evolved for acclimation of test fish, observation of test fish behavior at approach and upon exit from the turbine environment, and precise estimation of turbine passage mortality. Fish condition assessment continues to improve permitting better classification of observed injuries to injury mechanisms. Computational fluid dynamics (CFD) models and other computer models permit detailed investigation of the turbine passage environment and development of hypotheses that can be tested in field studies using live fish. Risk assessment techniques permit synthesis of laboratory and in-field study findings and estimation of population level effects over a wide range of turbine operation scenarios. Risk assessment is also evolving to provide input to turbine runner design. These developments, and others, have resulted in more productive biological performance assessment studies and will continue to evolve and improve the quantity and quality of information obtained from costly live fish hydroturbine passage studies. This paper reviews the history of hydro-turbine biological assessment, presents the current state-of-the-art, and identify areas needing improvement.

  4. EIS-0470: Cape Wind Energy Project, Nantucket Sound, Offshore of

    Energy Savers [EERE]

    Massachusetts | Department of Energy 0: Cape Wind Energy Project, Nantucket Sound, Offshore of Massachusetts EIS-0470: Cape Wind Energy Project, Nantucket Sound, Offshore of Massachusetts June 25, 2014 EIS-0470: Cape Wind Energy Project, Final General Conformity Determination Cape Wind Energy Project, Final General Conformity Determination, June 23, 2014 December 21, 2012 EIS-0470: Final Environmental Impact Statement Cape Wind Energy Project, Nantucket Sound, MA December 31, 2012 EIS-0470:

  5. Cape Verde: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Country Profile Name Cape Verde Population 512,096 GDP 2,071,000,000 Energy Consumption 0.00 Quadrillion Btu 2-letter ISO code CV 3-letter ISO code CPV Numeric ISO...

  6. Cape Wind Associates LLC | Open Energy Information

    Open Energy Info (EERE)

    is developing an offshore wind farm off the coast of Cape Cod in Massachussets, USA. Coordinates: 42.358635, -71.056699 Show Map Loading map... "minzoom":false,"mappi...

  7. Biological assessment of remedial action at the abandoned uranium mill tailings site near Naturita, Colorado

    SciTech Connect (OSTI)

    1996-03-01

    Pursuant to the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, the U.S. Department of Energy (DOE) is proposing to conduct remedial action to clean up the residual radioactive materials (RRM) at the Naturita uranium processing site in Colorado. The Naturita site is in Montrose County, Colorado, and is approximately 2 miles (mi) (3 kilometer [km]) from the unincorporated town of Naturita. The proposed remedial action is to remove the RRM from the Naturita site to the Upper Burbank Quarry at the Uravan disposal site. To address the potential impacts of the remedial action on threatened and endangered species, the DOE prepared this biological assessment. Informal consultations with the U.S. Department of the Interior, Fish and Wildlife Service (FWS) were initiated in 1986, and the FWS provided a list of the threatened and endangered species that may occur in the Naturita study area. This list was updated by two FWS letters in 1988 and by verbal communication in 1990. A biological assessment was included in the environmental assessment (EA) of the proposed remedial action that was prepared in 1990. This EA addressed the impacts of moving the Naturita RRM to the Dry Flats disposal site. In 1993, the design for the Dry Flats disposal alternative was changed. The FWS was again consulted in 1993 and provided a new list of threatened and endangered species that may occur in the Naturita study area. The Naturita EA and the biological assessment were revised in response to these changes. In 1994, remedial action was delayed because an alternate disposal site was being considered. The DOE decided to move the FIRM at the Naturita site to the Upper Burbank Quarry at the Uravan site. Due to this delay, the FWS was consulted in 1995 and a list of threatened and endangered species was provided. This biological assessment is a revision of the assessment attached to the Naturita EA and addresses moving the Naturita RRM to the Upper Burbank Quarry disposal site.

  8. West Cape May, New Jersey: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Hide Map This article is a stub. You can help OpenEI by expanding it. West Cape May is a borough in Cape May County, New Jersey. It falls under New Jersey's 2nd...

  9. DOE Offers Conditional Commitment to Cape Wind Offshore Wind Generation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project | Department of Energy Offers Conditional Commitment to Cape Wind Offshore Wind Generation Project DOE Offers Conditional Commitment to Cape Wind Offshore Wind Generation Project September 11, 2014 - 3:26pm Addthis The U.S. Department of Energy (DOE) recently announced the first step toward issuing a $150 million loan guarantee to support the construction of the Cape Wind offshore wind project with a conditional commitment to Cape Wind Associates, LLC. The project could be the first

  10. ARM Convective Available Potential Energy (CAPE), Convective Inhibition

    Office of Scientific and Technical Information (OSTI)

    (CIN) Product (Dataset) | Data Explorer Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) Product Title: ARM Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) Product ARM soundings are used to determine Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) and associated properties, using the following relationships; Authors: Jensen, Michael Publication Date: 2014-04-10 OSTI Identifier: 1127238 DOE Contract Number:

  11. EIS-0470: U.S. Department of Energy Loan Guarantee for the Cape Wind Energy Project on the Outer Continental Shelf off Massachusetts, Nantucket Sound

    Broader source: Energy.gov [DOE]

    The DOE Loan Programs Office is proposing to offer a loan guarantee to Cape Wind Associates, LLC for the construction and start-up of the Cape Wind Energy Project in Nantucket Sound, offshore of Massachusetts. The proposed Cape Wind Energy Project would consist of up to 130, 3.6-MW turbine generators, in an area of roughly 25-square miles, and would include 12.5 miles of 115-kilovolt submarine transmission cable and an electric service platform. To inform DOE's decision regarding a loan guarantee, DOE adopted the Department of the Interior’s 2009 Final Cape Wind Energy Project EIS, in combination with two Cape Wind Environmental Assessments dated May 2010 and April 2011 (per 40 CFR 1506.4), as a DOE Final EIS (DOE/EIS-0470). The adequacy of the Department of the Interior final EIS adopted by DOE is the subject of a judicial action. This project is inactive.

  12. Lake Whitney Comprehensive Water Quality Assessment, Phase 1B- Physical and Biological Assessment (USDOE)

    SciTech Connect (OSTI)

    Doyle, Robert D; Byars, Bruce W

    2009-11-24

    Baylor University Center for Reservoir and Aquatic Systems Research (CRASR) has conducted a phased, comprehensive evaluation of Lake Whitney to determine its suitability for use as a regional water supply reservoir. The area along the Interstate 35 corridor between Dallas / Fort Worth Metroplex and the Waco / Temple Centroplex represents one of the fastest growth areas in the State of Texas and reliable water supplies are critical to sustainable growth. Lake Whitney is situated midway between these two metropolitan areas. Currently, the City of Whitney as well as all of Bosque and Hill counties obtain their potable water from the Trinity Sands aquifer. Additionally, parts of the adjoining McLennan and Burleson counties utilize the Trinity sands aquifer system as a supplement to their surface water supplies. Population growth coupled with increasing demands on this aquifer system in both the Metroplex and Centroplex have resulted in a rapid depletion of groundwater in these rural areas. The Lake Whitney reservoir represents both a potentially local and regional solution for an area experiencing high levels of growth. Because of the large scope of this project as well as the local, regional and national implications, we have designed a multifaceted approach that will lead to the solution of numerous issues related to the feasibility of using Lake Whitney as a water resource to the region. Phase IA (USEPA, QAPP Study Elements 1-4) of this research focused on the physical limnology of the reservoir (bathymetry and fine scale salinity determination) and develops hydrodynamic watershed and reservoir models to evaluate how salinity would be expected to change with varying hydrologic and climatic factors. To this end, we implemented a basic water quality modeling program in collaboration with the Texas Parks and Wildlife Department and the Texas Commission on Environmental Quality to add to the developing long-term database on Lake Whitney. Finally, we conducted an initial assessment of knowledge of watershed and water quality related issues by local residents and stakeholders of Lake Whitney and design an intervention educational program to address any deficiencies discovered. Phase IA was funded primarily from EPA Cooperative Agreement X7-9769 8901-0. Phase IC (USEPA, QAPP Study Element 5) of this research focused on the ambient toxicity of the reservoir with respect to periodic blooms of golden algae. Phase IC was funded primarily from Cooperative Agreement EM-96638001. Phase 1B (USDOE, Study Elements 6-11) complemented work being done via EPA funding on study elements 1-5 and added five new study elements: 6) Salinity Transport in the Brazos Watershed to Lake Whitney; 7) Bacterial Assessment; 8) Organic Contaminant Analysis on Lake Whitney; 9) Plankton Photosynthesis; 10) Lake Whitney Resident Knowledge Assessment; and 11) Engineering Scoping Perspective: Recommendations for Use.

  13. Sitewide biological risk assessment Eielson Air Force Base, Alaska: Risks to terrestrial receptors from diverse contaminants

    SciTech Connect (OSTI)

    Brandt, C.A.; Becker, J.M.

    1995-12-31

    Eielson Air Force Base (AFB) is located southeast of Fairbanks, Alaska. Eielson AFB was listed by the US Environmental Protection Agency on the National Priorities List with a total of 64 potential terrestrial and aquatic source areas. Contaminants of concern include fuel and fuel components, pesticides, polychlorinated biphenyls (PCBs), and lead. As part of the remedial investigations of these sites, a biological risk assessment (BRA) was conducted to estimate the risk of ecological effects on terrestrial receptors posed by contaminants in the Eielson environment. There are 32 mammal species, 117 bird species, 17 fish species, and 1 amphibian species known to inhabit Eielson AFB and vicinity. The BRA screened source areas based on completed biological exposure pathways, selected receptors for analysis, estimated exposure of receptors to contaminants, and compared these exposures to known toxicological effects. Lower Garrison Slough and Flightline Pond posed a substantial risk for shrikes and goshawks. Ingestion of PCBs constituted the primary pathway/contaminant combination contributing to this risk. The effects of the various sources of uncertainty in the ingestion exposure calculations for these sites were evaluated in a probabilistic risk assessment using Monte Carlo methods. There was an 11% risk of reproductive effects from PCBs for goshawks feeding from Flightline Pond and a 25 % risk from lower Garrison Slough. There was an 81 % risk of reproductive effects from PCB exposure for shrikes feeding near lower Garrison Slough.

  14. Design Tools to Assess Hydro-Turbine Biological Performance: Priest Rapids Dam Turbine Replacement Project

    SciTech Connect (OSTI)

    Richmond, Marshall C.; Rakowski, Cynthia L.; Serkowski, John A.; Strickler, Brad; Weisbeck, Molly; Dotson, Curtis L.

    2013-06-25

    Over the past two decades, there have been many studies describing injury mechanisms associated with turbine passage, the response of various fish species to these mechanisms, and the probability of survival through dams. Although developing tools to design turbines that improve passage survival has been difficult and slow, a more robust quantification of the turbine environment has emerged through integrating physical model data, fish survival data, and computational fluid dynamics (CFD) studies. Grant County Public Utility District (GCPUD) operates the Priest Rapids Dam (PRD), a hydroelectric facility on the Columbia River in Washington State. The dam contains 10 Kaplan-type turbine units that are now almost 50 years old. The Utility District plans to refit all of these aging turbines with new turbines. The Columbia River at PRD is a migratory pathway for several species of juvenile and adult salmonids, so passage of fish through the dam is a major consideration when replacing the turbines. In this presentation, a method for turbine biological performance assessment (BioPA) is introduced. Using this method, a suite of biological performance indicators is computed based on simulated data from a CFD model of a proposed turbine design. Each performance indicator is a measure of the probability of exposure to a certain dose of an injury mechanism. Using known relationships between the dose of an injury mechanism and frequency of injury (dose–response) from laboratory or field studies, the likelihood of fish injury for a turbine design can be computed from the performance indicator. By comparing the values of the indicators from proposed designs, the engineer can identify the more-promising alternatives. We will present application of the BioPA method for baseline risk assessment calculations for the existing Kaplan turbines at PRD that will be used as the minimum biological performance that a proposed new design must achieve.

  15. Baseline biological risk assessment for aquatic populations occurring near Eielson Air Force Base, Alaska

    SciTech Connect (OSTI)

    Dauble, D.; Brandt, C.; Lewis, R.; Smith, R.

    1995-12-31

    Eielson Air Force Base (AFB), Alaska was listed as a Superfund site in November 1989 with 64 potential source areas of contamination. As part of a sitewide remedial investigation, baseline risk assessments were conducted in 1993 and 1994 to evaluate hazards posed to biological receptors and to human health. Fish tissue, aquatic invertebrates, aquatic vegetation, sediment, and surface water data were collected from several on-site and off-site surface water bodies. An initial screening risk assessment indicated that several surface water sites along two major tributary creeks flowing through the base had unacceptable risks to both aquatic receptors and to human health because of DDTs. Other contaminants of concern (i.e., PCBs and PAHs) were below screening risk levels for aquatic organisms, but contributed to an unacceptable risk to human health. Additional samples was taken in 1994 to characterize the site-wide distribution of PAHs, DDTs, and PCBs in aquatic biota and sediments. Concentrations of PAHs were invertebrates > aquatic vegetation > fish, but concentrations were sufficiently low that they posed no significant risk to biological receptors. Pesticides were detected in all fish tissue samples. Polychlorinated biphenyls (PCBs) were also detected in most fish from Garrison Slough. The pattern of PCB concentrations in Arctic grayling (Thymallus arcticus) was related to their proximity to a sediment source in lower Garrison Slough. Ingestion of PCB-contaminated fish is the primary human-health risk driver for surface water bodies on Eielson AFB, resulting in carcinogenic risks > 1 {times} 10{sup {minus}4} for future recreational land-use at some sites. Principal considerations affecting uncertainty in the risk assessment process included spatial and temporal variability in media contaminant concentrations and inconsistencies between modelled and measured body burdens.

  16. Biological assessments for the low energy demonstration accelerator, 1996 and 1997

    SciTech Connect (OSTI)

    Cross, S.

    1998-12-31

    The Department of Energy (DOE) plans to build, install, and operate a Low Energy Demonstration Accelerator (LMA) in Technical Area 53 of the Los Alamos National Laboratory (LANL). LEDA will demonstrate the accelerator technology necessary to produce tritium, but is not designed to produce tritium at LANL. USFWS reviewers of the Biological Assessment prepared for LEDA insisted that the main drainage be monitored to measure and document changes to vegetation, soils, wildlife, and habitats due to LEDA effluent discharges. The Biology Team of ESH-20 (LANL`s Ecology Group) has performed these monitoring activities during 1996 and 1997 to document baseline conditions before LEDA released significant effluent discharges. Quarterly monitoring of the outfall which will discharge LEDA blowdown effluent had one exceedance of permitted parameters, a high chlorine discharge that was quickly remedied. Samples from 12 soil pits in the drainage area contained no hydric indicators, such as organic matter in the upper layers, streaking, organic pans, and oxidized rhizospheres. Vegetation transacts in the meadows that LEDA discharges will flow through contained 44 species of herbaceous plants, all upland taxa. Surveys of resident birds, reptiles, and amphibians documented a fauna typical of local dry canyons. No threatened or endangered species inhabit the project area, but increased effluent releases may make the area more attractive to many wildlife species, an endangered raptor, and several other species of concern. Biological best management practices especially designed for LEDA are discussed, including protection of floodplains, erosion control measures, hazards posed by increased usage of the area by deer and elk and revegetation of disturbed areas.

  17. Biological assessment for the remedial action at the chemical plant area of the Weldon Spring site

    SciTech Connect (OSTI)

    Hlohowskyj, I.; Dunn, C.P.

    1992-11-01

    The Weldon Spring site in St.Charles County, Missouri, became contaminated during the 1940s through the 1960s as a result of explosives production by the US Army and uranium and thorium processing by the predecessor agency of the US Department of Energy (DOE). The site is listed on the National Priorities List of the US Environmental Protection Agency, and DOE is responsible for its cleanup. Contaminants are present in soil, surface water, and aquatic sediments. Alternatives identified for site remediation are no action (included as baseline for comparison), treatment and disposal of the wastes at the Weldon Spring site, and on-site treatment followed by off-site disposal at either a commercial facility near Clive, Utah, or at DOE`s Hanford site near Richland, Washington. In accordance with the requirements of the Endangered Species Act, this biological assessment has been prepared to evaluate the potential effects of proposed remedial action alternatives on federal listed (endangered or threatened) and candidate species at the respective sites. The assessment includes consideration of the environmental setting at each site; the federal listed and candidate species that could occur at each site; the construction, excavation, and treatment activities under each alternative; and the amount of land area affected at each site.

  18. Biological assessment for the remedial action at the chemical plant area of the Weldon Spring site

    SciTech Connect (OSTI)

    Hlohowskyj, I.; Dunn, C.P.

    1992-11-01

    The Weldon Spring site in St.Charles County, Missouri, became contaminated during the 1940s through the 1960s as a result of explosives production by the US Army and uranium and thorium processing by the predecessor agency of the US Department of Energy (DOE). The site is listed on the National Priorities List of the US Environmental Protection Agency, and DOE is responsible for its cleanup. Contaminants are present in soil, surface water, and aquatic sediments. Alternatives identified for site remediation are no action (included as baseline for comparison), treatment and disposal of the wastes at the Weldon Spring site, and on-site treatment followed by off-site disposal at either a commercial facility near Clive, Utah, or at DOE's Hanford site near Richland, Washington. In accordance with the requirements of the Endangered Species Act, this biological assessment has been prepared to evaluate the potential effects of proposed remedial action alternatives on federal listed (endangered or threatened) and candidate species at the respective sites. The assessment includes consideration of the environmental setting at each site; the federal listed and candidate species that could occur at each site; the construction, excavation, and treatment activities under each alternative; and the amount of land area affected at each site.

  19. Cape Town, South Africa: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Systems Registered Energy Companies in Cape Town, South Africa Atlantic Solar Genesis Eco Energy Mulilo Renewable Energy Pty Ltd SetSolar References http:www.geonames.org...

  20. Cape Girardeau County, Missouri: Energy Resources | Open Energy...

    Open Energy Info (EERE)

    Cape Girardeau, Missouri Delta, Missouri Dutchtown, Missouri Gordonville, Missouri Jackson, Missouri Oak Ridge, Missouri Old Appleton, Missouri Pocahontas, Missouri Scott City,...

  1. Cape Peninsula University of Technology - Centre for Distributed...

    Open Energy Info (EERE)

    Power and Electronic Systems is a research institution based in Cape Town, South Africa. References "Dr Atanda Raji" "Prof. Kahn MTE" "Dr Marco Adonis" "Dr...

  2. ARM Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) Product

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Jensen, Michael

    ARM soundings are used to determine Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) and associated properties, using the following relationships;

  3. Cape Light Compact- Residential Energy Efficiency Rebate Program

    Broader source: Energy.gov [DOE]

    Cape Light Compact (CLC) offers a variety of financial incentives to customers for purchasing energy efficient residential equipment. Residential customers can take advantage of incentives on...

  4. ARM Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) Product

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Jensen, Michael

    2014-04-10

    ARM soundings are used to determine Convective Available Potential Energy (CAPE), Convective Inhibition (CIN) and associated properties, using the following relationships;

  5. Cape May Court House, New Jersey: Energy Resources | Open Energy...

    Open Energy Info (EERE)

    County, New Jersey.1 Registered Energy Companies in Cape May Court House, New Jersey Cap May County Municipal Utilities Authority References US Census Bureau 2005 Place to...

  6. Cape May County, New Jersey: Energy Resources | Open Energy Informatio...

    Open Energy Info (EERE)

    4 Climate Zone Subtype A. Registered Energy Companies in Cape May County, New Jersey Cap May County Municipal Utilities Authority Fishermen s Energy Fishermen s Energy of New...

  7. Cape Verde Archipelago Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    Energy, Wind Topics Finance, Market analysis, Background analysis Website http:www.europa-eu-un.orgar Program Start 2010 Country Cape Verde UN Region Western Africa References...

  8. For Cape Wind, Summer Breeze Makes Offshore Wind Feel Fine

    Broader source: Energy.gov [DOE]

    The Department of Energy announced that it has issued a conditional commitment for a $150 million loan guarantee to the Cape Wind Project, which would be the first offshore wind energy project in the U.S. if constructed off Nantucket Sound. It could supply approximately 75 percent of the electricity needs of Cape Cod and the Islands.

  9. Cape Coral Youth Center Helps Light the Way to Energy Savings | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Cape Coral Youth Center Helps Light the Way to Energy Savings Cape Coral Youth Center Helps Light the Way to Energy Savings May 18, 2011 - 4:32pm Addthis Cape Coral Youth Center Manager Mark Cagel stands in front of a tamper-proof thermostat at the Austen Youth Center in Cape Coral, Florida. | Photo Courtesy of the Cape Coral Youth Center Cape Coral Youth Center Manager Mark Cagel stands in front of a tamper-proof thermostat at the Austen Youth Center in Cape Coral, Florida. |

  10. EECBG Success Story: Cape Coral Youth Center Helps Light the...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The city of Cape Coral, Florida -- a town of located on the coast of the Gulf of Mexico -- is using funding from the Energy Efficiency and Conservation Block Grant (EECBG) program ...

  11. Cape Light Compact- Commercial Energy Efficiency Rebate Program

    Broader source: Energy.gov [DOE]

    Through a multi-member partnership, Cape Light Compact (CLC) and Mass Save offer a variety of financial incentives for commercial and industrial facilities. Custom rebate options are available for...

  12. Office of Enterprise Assessments Targeted Review of Work Planning and Control and Biological Safety at the Los Alamos National Laboratory … December 2015

    Energy Savers [EERE]

    Targeted Review of Work Planning and Control and Biological Safety at the Los Alamos National Laboratory December 2015 Office of Worker Safety and Health Assessments Office of Environment, Safety and Health Assessments Office of Enterprise Assessments U.S. Department of Energy i Table of Contents Acronyms ...................................................................................................................................................... ii Executive Summary

  13. Biological alternatives to chemical identification for the ecotoxicological assessment of industrial effluents: The RTG-2 in vitro cytotoxicity test

    SciTech Connect (OSTI)

    Castano, A. . Centro de Sanidad Ambiental); Vega, M.; Blazquez, T.; Tarazona, J.V. )

    1994-10-01

    Ecotoxicology is concerned with the effects of chemicals on biological systems. Identifying components of complex aqueous effluents poses special problems, and can be useless if there is a lack of information on the biological effects of the identified chemicals. Toxicity-based (bioassay-directed) sample fractionation can be very useful, but the small amount of fractioned material is a constraint that can be solved by using in vitro tests. The RTG-2 in vitro cytotoxicity test has been used to assess (a) the efficacy of a treatment plant in the aeronautics industry and (b) the exposure of fish and molluscs cultured in Esteiro Bay to the effluent of a fish-processing factory. Ecotoxicological assessments could be done without identifying the responsible chemicals. The RTG-2 test was used in combination with concentration/fractionation procedures. It proved that the toxicity of the liquid wastes from the aeronautics industry was eliminated by the treatment, and that molluscs and fish reared in Esteiro Bay had accumulated toxic chemicals dumped by the fish-processing factory. A combination of the RTG-2 cytotoxicity test and HPLC proved to give useful information even for chemicals not identified by GC-MS.

  14. Energy Department Offers Conditional Commitment to Cape Wind Offshore Wind Generation Project

    Broader source: Energy.gov [DOE]

    The Department of Energy today announced the first step toward issuing a $150 million loan guarantee to support the construction of the Cape Wind offshore wind project with a conditional commitment to Cape Wind Associates, LLC.

  15. Programmatic Biological Assessment

    Broader source: Energy.gov (indexed) [DOE]

    may also be present. Threatened, Endangered, and Culturally Sensitive Species The U.S. Fish and Wildlife Service (USFWS) list of threatened, endangered, candidate, and proposed...

  16. DOE Zero Energy Ready Home Case Study: John Hubert Associates, North Cape

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    May, NJ | Department of Energy John Hubert Associates, North Cape May, NJ DOE Zero Energy Ready Home Case Study: John Hubert Associates, North Cape May, NJ DOE Zero Energy Ready Home Case Study: John Hubert Associates, North Cape May, NJ Case study of a DOE Zero Energy Ready home in North Cape May, NJ, that scored a HERS 46 without PV or HERS 9 with 6.5 kW of PV. The two-story, 1,871-ft2 home has advanced-framed above-grade walls with R-21 fiberglass batt plus an R-3.6-insulated coated OSB

  17. MHK Projects/Wavemill Energy Cape Breton Island NS CA | Open...

    Open Energy Info (EERE)

    Wavemill Energy Cape Breton Island NS CA < MHK Projects Jump to: navigation, search << Return to the MHK database homepage Loading map... "minzoom":false,"mappingservice":"googlem...

  18. Sensitivity of MJO to the CAPE lapse time in the NCAR CAM3

    SciTech Connect (OSTI)

    LIU, P.; Wang, B.; Meehl, Gerald, A.

    2007-09-05

    Weak and irregular boreal winter MJO in the NCAR CAM3 corresponds to very low CAPE background, which is caused by easy-to-occur and over-dominant deep convection indicating the deep convective scheme uses either too low CAPE threshold as triggering function or too large consumption rate of CAPE to close the scheme. Raising the CAPE threshold from default 70 J/kg to ten times large only enhances the CAPE background while fails to noticeably improve the wind mean state and the MJO. However, lengthening the CAPE lapse time from one to eight hours significantly improved the background in CAPE and winds, and salient features of the MJO. Variances, dominant periods and zonal wave numbers, power spectra and coherent propagating structure in winds and convection associated with MJO are ameliorated and comparable to the observations. Lengthening the CAPE lapse time to eight hours reduces dramatically the cloud base mass flux, which prevents effectively the deep convection from occurring prematurely. In this case, partitioning of deep to shallow convection in MJO active area is about 5:4.5 compared to over 9:0.5 in the control run. Latent heat is significantly enhanced below 600 hPa over the central Indian Ocean and the western Pacific. Such partitioning of deep and shallow convection is argued necessary for simulating realistic MJO features. Although the universal eight hours lies in the upper limit of that required by the quasi-equilibrium theory, a local CAPE lapse time for the parameterized cumulus convection will be more realistic.

  19. Fuel Cell Demonstration at the U.S. Coast Guard Air Station Cape Cod

    SciTech Connect (OSTI)

    Halverson, Mark A.; Chvala, William D.; Herrera, Shawn

    2005-07-30

    Journal article reporting on the 250-kW fuel cell combined heat and power plant located at the U.S. Coast Guard Air Station Cape Code in Bourne, Massachusetts.

  20. EECBG Success Story: Cape Coral Youth Center Helps Light the Way to Energy Savings

    Broader source: Energy.gov [DOE]

    The city of Cape Coral, Florida -- a town of located on the coast of the Gulf of Mexico -- is using funding from the Energy Efficiency and Conservation Block Grant (EECBG) program to help reduce the city’s energy use by 40% over the next 15 years. Learn more.

  1. DOE Zero Energy Ready Home Case Study: John Hubert Associates, North Cape May, NJ

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready home in North Cape May, NJ, that scored a HERS 46 without PV or HERS 9 with 6.5 kW of PV. The two-story, 1,871-ft2 home has advanced-framed above-grade walls...

  2. Biological assessment of the effects of construction and operation of a depleted uranium hexafluoride conversion facility at the Paducah, Kentucky, site.

    SciTech Connect (OSTI)

    Van Lonkhuyzen, R.

    2005-09-09

    The U.S. Department of Energy (DOE) Depleted Uranium Hexafluoride (DUF{sub 6}) Management Program evaluated alternatives for managing its inventory of DUF{sub 6} and issued the ''Programmatic Environmental Impact Statement for Alternative Strategies for the Long-Term Management and Use of Depleted Uranium Hexafluoride'' (DUF{sub 6} PEIS) in April 1999 (DOE 1999). The DUF{sub 6} inventory is stored in cylinders at three DOE sites: Paducah, Kentucky; Portsmouth, Ohio; and East Tennessee Technology Park (ETTP), near Oak Ridge, Tennessee. In the Record of Decision for the DUF{sub 6} PEIS, DOE stated its decision to promptly convert the DUF6 inventory to a more stable chemical form. Subsequently, the U.S. Congress passed, and the President signed, the ''2002 Supplemental Appropriations Act for Further Recovery from and Response to Terrorist Attacks on the United States'' (Public Law No. 107-206). This law stipulated in part that, within 30 days of enactment, DOE must award a contract for the design, construction, and operation of a DUF{sub 6} conversion plant at the Department's Paducah, Kentucky, and Portsmouth, Ohio, sites, and for the shipment of DUF{sub 6} cylinders stored at ETTP to the Portsmouth site for conversion. This biological assessment (BA) has been prepared by DOE, pursuant to the National Environmental Policy Act of 1969 (NEPA) and the Endangered Species Act of 1974, to evaluate potential impacts to federally listed species from the construction and operation of a conversion facility at the DOE Paducah site.

  3. Biological Safety

    Broader source: Energy.gov [DOE]

    The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

  4. Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Assessment of the Surveillance Program of the High-Level Waste Storage Tanks at Hanford :.~I LALI i~E REJ 163 ROOM 1t 4 F77L.~ ~ -_77 .:earmn OfEeg Asitn Sertr fo niomn 4 z. r _________ rment of the Surveilance Prograrn of the High-Level Storage- Tanks at Hanford P. E WOOD Robert J. Catln, Deputy Directat - Office of Environmental Compliance and Overview Office of Environment MARCH 1980 Report to the U.S. Departrent of Energy Assistant Secretary for Environment Washkngon, DC C March 27, 1980

  5. Review of the physical oceanography of the Cape Hatteras, North Carolina Region. Volume 1. Literature synthesis

    SciTech Connect (OSTI)

    Adams, C.E.; Berger, T.J.; Boicourt, W.C.; Churchill, J.H.; Earle, M.D.

    1993-10-01

    The present study is part of a sequence of programs designed to provide the MMS with a basis for evaluating the potential environmental impacts of oil and gas production off of the Cape Hatteras region. The primary objective of this review is to summarize and critique the present state of knowledge of the physical oceanography of the complex region offshore of Cape Hatteras, North Carolina, within the context of understanding the regional circulation and its relation to the fate of any discharges resulting from offshore oil and gas activity. The two other related objectives are to produce an annotated bibliography of the pertinent literature, primarily from 1970 to the present, and to identify relevant oceanographic data sets which can provide a basis for an improved understanding of circulation patterns and physical oceanographic conditions in the study area.

  6. Benthic study of the continental slope off Cape Hatteras, North Carolina. Volume 2. Final report

    SciTech Connect (OSTI)

    Diaz, R.J.; Blake, J.A.; Lohse, D.P.

    1993-03-01

    A number of blocks off Cape Hatteras have been leased by Mobil Oil, which has requested permission to drill an exploratory well, at 820-m depth, in a block identified as Manteo 467. The proposed well location is 39 miles from the coast of North Carolina. The possibility of extracting gas from the continental slope off the coast of North Carolina, particularly at slope depths, has raised a number of environmental concerns that cannot be addressed from existing data. The present study was developed by the Minerals Management Service to better define the nature of the continental slope benthic communities off Cape Hatteras and to delineate their areal extent. Emphasis was placed on the area around the proposed drill site in the Manteo 467 lease block.

  7. National Laboratory] Basic Biological Sciences(59) Biological...

    Office of Scientific and Technical Information (OSTI)

    Achievements of structural genomics Terwilliger, Thomas C. Los Alamos National Laboratory Basic Biological Sciences(59) Biological Science Biological Science Abstract Not...

  8. Biological assessment of the effects of construction and operation of adepleted uranium hexafluoride conversion facility at the Portsmouth, Ohio,site.

    SciTech Connect (OSTI)

    Van Lonkhuyzen, R.

    2005-09-09

    The U.S. Department of Energy (DOE) Depleted Uranium Hexafluoride (DUF{sub 6}) Management Program evaluated alternatives for managing its inventory of DUF{sub 6} and issued the ''Programmatic Environmental Impact Statement for Alternative Strategies for the Long-Term Management and Use of Depleted Uranium Hexafluoride'' (DUF{sub 6} PEIS) in April 1999 (DOE 1999). The DUF{sub 6} inventory is stored in cylinders at three DOE sites: Paducah, Kentucky; Portsmouth, Ohio; and East Tennessee Technology Park (ETTP), near Oak Ridge, Tennessee. In the Record of Decision for the DUF{sub 6} PEIS, DOE stated its decision to promptly convert the DUF{sub 6} inventory to a more stable chemical form. Subsequently, the U.S. Congress passed, and the President signed, the ''2002 Supplemental Appropriations Act for Further Recovery from and Response to Terrorist Attacks on the United States'' (Public Law No. 107-206). This law stipulated in part that, within 30 days of enactment, DOE must award a contract for the design, construction, and operation of a DUF{sub 6} conversion plant at the Department's Paducah, Kentucky, and Portsmouth, Ohio, sites, and for the shipment of DUF{sub 6} cylinders stored at ETTP to the Portsmouth site for conversion. This biological assessment (BA) has been prepared by DOE, pursuant to the National Environmental Policy Act of 1969 and the Endangered Species Act of 1974, to evaluate potential impacts to federally listed species from the construction and operation of a conversion facility at the DOE Portsmouth site. The Indiana bat is known to occur in the area of the Portsmouth site and may potentially occur on the site during spring or summer. Evaluations of the Portsmouth site indicated that most of the site was found to have poor summer habitat for the Indiana bat because of the small size, isolation, and insufficient maturity of the few woodlands on the site. Potential summer habitat for the Indiana bat was identified outside the developed area bounded by Perimeter Road, within the corridors along Little Beaver Creek, the Northwest Tributary stream, and a wooded area east of the X-100 facility. However, no Indiana bats were collected during surveys of these areas in 1994 and 1996. Locations A, B, and C do not support suitable habitat for the Indiana bat and would be unlikely to be used by Indiana bats. Indiana bat habitat also does not occur at Proposed Areas 1 and 2. Although Locations A and C contain small wooded areas, the small size and lack of suitable maturity of these areas indicate that they would provide poor habitat for Indiana bats. Trees that may be removed during construction would not be expected to be used for summer roosting by Indiana bats. Disturbance of Indiana bats potentially roosting or foraging in the vicinity of the facility during operations would be very unlikely, and any disturbance would be expected to be negligible. On the basis of these considerations, DOE concludes that the proposed action is not likely to adversely affect the Indiana bat. No critical habitat exists for this species in the action area. Although the timber rattlesnake occurs in the vicinity of the Portsmouth site, it has not been observed on the site. In addition, habitat for the timber rattlesnake is not present on the Portsmouth site. Therefore, DOE concludes that the proposed action would not affect the timber rattlesnake.

  9. Biological preconcentrator

    DOE Patents [OSTI]

    Manginell, Ronald P.; Bunker, Bruce C.; Huber, Dale L.

    2008-09-09

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  10. Benthic study of the continental slope off Cape Hatteras, North Carolina. Volume 3. Appendices

    SciTech Connect (OSTI)

    Diaz, R.J.; Blake, J.A.; Lohse, D.P.

    1993-03-01

    The Point is an area that supports a most productive pelagic fishery, including tuna, swordfish, marlin, and more. The objective of the study is to analyze video tapes from near the Point, in order to provide data on epibenthic, megafaunal invertebrates including species composition, relative abundances, and large scale (1 km) distribution. The Point is not a defined spot on a chart. Although fishermen do use the steep shelf break for location, they generally look for the west wall of the Gulf Stream. The Point and the oil lease site coincidentally occur where the Gulf Stream parts the continental slope, just north of the eastern-most tip of Cape Hatteras.

  11. Review of the physical oceanography of the Cape Hatteras, North Carolina Region. Volume 1. Literature synthesis. Appendix A. Annotated bibliography

    SciTech Connect (OSTI)

    Adams, C.E.; Berger, T.J.; Boicourt, W.C.; Churchill, J.H.; Earle, M.D.

    1993-10-01

    The report, second in a three set series, is an annotated bibliography of the pertinent literature, primarily from 1970 to the present. The literature discusses the physical oceanography of the complex region offshore of Cape Hatteras, North Carolina as it relates to the ocean circulation and fate of any discharges resulting from offshore oil and gas activity.

  12. Package Equivalent Reactor Networks as Reduced Order Models for Use with CAPE-OPEN Compliant Simulation

    SciTech Connect (OSTI)

    Meeks, E.; Chou, C. -P.; Garratt, T.

    2013-03-31

    Engineering simulations of coal gasifiers are typically performed using computational fluid dynamics (CFD) software, where a 3-D representation of the gasifier equipment is used to model the fluid flow in the gasifier and source terms from the coal gasification process are captured using discrete-phase model source terms. Simulations using this approach can be very time consuming, making it difficult to imbed such models into overall system simulations for plant design and optimization. For such system-level designs, process flowsheet software is typically used, such as Aspen Plus® [1], where each component where each component is modeled using a reduced-order model. For advanced power-generation systems, such as integrated gasifier/gas-turbine combined-cycle systems (IGCC), the critical components determining overall process efficiency and emissions are usually the gasifier and combustor. Providing more accurate and more computationally efficient reduced-order models for these components, then, enables much more effective plant-level design optimization and design for control. Based on the CHEMKIN-PRO and ENERGICO software, we have developed an automated methodology for generating an advanced form of reduced-order model for gasifiers and combustors. The reducedorder model offers representation of key unit operations in flowsheet simulations, while allowing simulation that is fast enough to be used in iterative flowsheet calculations. Using high-fidelity fluiddynamics models as input, Reaction Design’s ENERGICO® [2] software can automatically extract equivalent reactor networks (ERNs) from a CFD solution. For the advanced reduced-order concept, we introduce into the ERN a much more detailed kinetics model than can be included practically in the CFD simulation. The state-of-the-art chemistry solver technology within CHEMKIN-PRO allows that to be accomplished while still maintaining a very fast model turn-around time. In this way, the ERN becomes the basis for high-fidelity kinetics simulation, while maintaining the spatial information derived from the geometrically faithful CFD model. The reduced-order models are generated in such a way that they can be easily imported into a process flowsheet simulator, using the CAPE-OPEN architecture for unit operations. The ENERGICO/CHEMKIN-PRO software produces an ERN-definition file that is read by a dynamically linked library (DLL) that can be easily linked to any CAPE-OPEN compliant software. The plug-in unitoperation module has been successfully demonstrated for complex ERNs of coal gasifiers, using both Aspen Plus and COFE process flowsheet simulators through this published CAPE-OPEN interface.

  13. Experimental and life cycle assessment analysis of gas emission from mechanicallybiologically pretreated waste in a landfill with energy recovery

    SciTech Connect (OSTI)

    Di Maria, Francesco Sordi, Alessio; Micale, Caterina

    2013-11-15

    Highlights: Bio-methane landfill emissions from different period (0, 4, 8, 16 weeks) MTB waste have been evaluated. Electrical energy recoverable from landfill gas ranges from 11 to about 90 kW h/tonne. Correlation between oxygen uptake, energy recovery and anaerobic gas production shows R{sup 2} ranging from 0.78 to 0.98. LCA demonstrate that global impact related to gaseous emissions achieve minimum for 4 week of MBT. - Abstract: The global gaseous emissions produced by landfilling the Mechanically Sorted Organic Fraction (MSOF) with different weeks of Mechanical Biological Treatment (MBT) was evaluated for an existing waste management system. One MBT facility and a landfill with internal combustion engines fuelled by the landfill gas for electrical energy production operate in the waste management system considered. An experimental apparatus was used to simulate 0, 4, 8 and 16 weeks of aerobic stabilization and the consequent biogas potential (Nl/kg) of a large sample of MSOF withdrawn from the full-scale MBT. Stabilization achieved by the waste was evaluated by dynamic oxygen uptake and fermentation tests. Good correlation coefficients (R{sup 2}), ranging from 0.7668 to 0.9772, were found between oxygen uptake, fermentation and anaerobic test values. On the basis of the results of several anaerobic tests, the methane production rate k (year{sup ?1}) was evaluated. k ranged from 0.436 to 0.308 year{sup ?1} and the bio-methane potential from 37 to 12 N m{sup 3}/tonne, respectively, for the MSOF with 0 and 16 weeks of treatment. Energy recovery from landfill gas ranged from about 11 to 90 kW h per tonne of disposed MSOF depending on the different scenario investigated. Life cycle analysis showed that the scenario with 0 weeks of pre-treatment has the highest weighted global impact even if opposite results were obtained with respect to the single impact criteria. MSOF pre-treatment periods longer than 4 weeks showed rather negligible variation in the global impact of system emissions.

  14. Theoretical Biology and Biophysics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    6 Theoretical Biology and Biophysics Modeling biological systems and analysis and informatics of molecular and cellular biological data Mathematical Biology/Immunology Fundamental science and modeling enabling host-pathogen science Computational Structural Biology Understanding biomolecule function by determining their 3-D macromolecular structure Bioinformatics and Epidemiology Sequence analysis using advanced algorithms, software, computational hardware Contacts Group Leader Nick Hengartner

  15. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cells, viruses), plant or soil samples (USDA quarantines), recombinant DNA, or blood-borne pathogen. Biological Use Authorization The great majority of biological work at...

  16. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Highlights Training Workshops & Summer Schools Summer Students Structural Molecular Biology Illuminating Biological Structures at the Atomic and Molecular Levels Your browser...

  17. CAPE-OPEN Integration for Advanced Process Engineering Co-Simulation

    SciTech Connect (OSTI)

    Zitney, S.E.

    2006-11-01

    This paper highlights the use of the CAPE-OPEN (CO) standard interfaces in the Advanced Process Engineering Co-Simulator (APECS) developed at the National Energy Technology Laboratory (NETL). The APECS system uses the CO unit operation, thermodynamic, and reaction interfaces to provide its plug-and-play co-simulation capabilities, including the integration of process simulation with computational fluid dynamics (CFD) simulation. APECS also relies heavily on the use of a CO COM/CORBA bridge for running process/CFD co-simulations on multiple operating systems. For process optimization in the face of multiple and some time conflicting objectives, APECS offers stochastic modeling and multi-objective optimization capabilities developed to comply with the CO software standard. At NETL, system analysts are applying APECS to a wide variety of advanced power generation systems, ranging from small fuel cell systems to commercial-scale power plants including the coal-fired, gasification-based FutureGen power and hydrogen production plant.

  18. Geology and ground shaking: The April 25--26, 1992 Cape Mendocino earthquake sequence

    SciTech Connect (OSTI)

    Moley, K.; Dengler, L. . Dept. of Geology)

    1993-04-01

    The authors present a simplified geologic map of Humboldt and Del Norte Counties, California and compare it to Modified Mercalli Intensities (MMI) produced by the April 25, 1992 M[sub S] = 7.1, and April 26 Ms = 6.6, and Ms = 6.7 Cape Mendocino earthquakes. The generalized geology was compiled from California Division of Mines and Geology Regional Geology Maps, and area geologic mapping by the USGS and Humboldt State University. Six rock/sediment groups are distinguished by considering lithology, consolidation, compaction, bedding orientation and degree of shearing: (1) landslides and glacial deposits; (2) bay muds and fill, alluvium, lake deposits and beach sand; (3) quaternary marine and non-marine deposits; (4) unstable bedrock; (5) moderately stable bedrock; (6) intrusions. Intensity values for the Saturday earthquake were calculated from over 2,000 surveys to individuals and businesses in the northcoast area by an algorithm based on a weighted sum of survey responses. Numerical data was compiled for over 100 locations in the region. The intensity VIII and greater zone encompassed an area of about 500 km[sup 2] including the communities of Petrolia, Ferndale and Rio Dell. Ground motion generally decays with distance in a roughly radial pattern. A different approach was taken to estimate the pattern of shaking in the two Sunday earthquakes. These earthquakes occurred when most respondents were sleeping and their perception of ground motion was likely to be affected.

  19. Biological conversion system

    DOE Patents [OSTI]

    Scott, C.D.

    A system for bioconversion of organic material comprises a primary bioreactor column wherein a biological active agent (zymomonas mobilis) converts the organic material (sugar) to a product (alcohol), a rejuvenator column wherein the biological activity of said biological active agent is enhanced, and means for circulating said biological active agent between said primary bioreactor column and said rejuvenator column.

  20. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, J.M.; Palumbo, A.V.

    1998-09-15

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer. 2 figs.

  1. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, Janet M. (Ten Mile, TN); Palumbo, Anthony V. (Oak Ridge, TN)

    1998-01-01

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer.

  2. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2013-02-26

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  3. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M.; McDowell, Andrew F.

    2015-11-24

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  4. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2014-04-15

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  5. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work cover diverse fields such as energy, agriculture, and environmental cleanup. Contact Us Babetta Marrone Biofuels Program Manager Email Cheryl Kuske DOE BER Biological System Science Division Program Manager Email Kirsten McCabe Emerging Threats Program Manager Email Rebecca McDonald Bioscience Communications Email "We

  6. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team genetically modified the organisms to harvest light more efficiently for maximum production. Overview of Research and Highlights Researchers at Los Alamos National Laboratory are using their renowned expertise in genomics, computation, and experimental biology as the foundation of a dynamic systems biology capability. Systems

  7. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Our Mission Our Mission The SSRL Structural Molecular Biology program operates as a integrated resource and has three primary areas (or cores) of technological research and...

  8. Integrated Biological Control

    SciTech Connect (OSTI)

    JOHNSON, A.R.

    2002-09-01

    Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects; and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (apriori) or in response to existing contamination spread (aposteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and apriori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, aposteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

  9. Integrated Biological Control

    SciTech Connect (OSTI)

    JOHNSON, A.R.

    2003-10-09

    Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects, and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (a priori) or in response to existing contamination spread (a posteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and a priori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, a posteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

  10. Biological sample collector

    DOE Patents [OSTI]

    Murphy, Gloria A.

    2010-09-07

    A biological sample collector is adapted to a collect several biological samples in a plurality of filter wells. A biological sample collector may comprise a manifold plate for mounting a filter plate thereon, the filter plate having a plurality of filter wells therein; a hollow slider for engaging and positioning a tube that slides therethrough; and a slide case within which the hollow slider travels to allow the tube to be aligned with a selected filter well of the plurality of filter wells, wherein when the tube is aligned with the selected filter well, the tube is pushed through the hollow slider and into the selected filter well to sealingly engage the selected filter well and to allow the tube to deposit a biological sample onto a filter in the bottom of the selected filter well. The biological sample collector may be portable.

  11. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal process or may be completed as an independent document. In the ESS, identify each material (including all biological materials) with which you will be working. The regulatory oversight for biological work is very complicated and we need to understand the risk levels involved with the material you plan to use at the ALS,

  12. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal process or may be completed as an independent document. In the ESS, identify each material (including all biological materials) with which you will be working. The regulatory oversight for biological work is very complicated and we need to understand the risk levels involved with the material you plan to use at the ALS,

  13. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal...

  14. Biological Hydrogen Production Workshop

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL) held a Biological Hydrogen Production Workshop on September 24–25, 2013, in Golden, Colorado. The workshop...

  15. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological and Environmental Research Biological and Environmental Research Understanding how genomic information is translated to functional capabilities, and the roles of Earth's biogeochemical systems so we can predict climate decades or centuries into the future. Get Expertise Cheryl Kuske (505) 665-4800 Email James Bossert (505) 667-3644 Email Manvendra Dubey (505) 665-3128 Email Kim Nitschke (505) 667-1186 Email Phil Jones (505) 667-6387 Email Cathy Wilson (505) 667-0202 Email Conducting

  16. Green Biologics | Open Energy Information

    Open Energy Info (EERE)

    Biologics Jump to: navigation, search Name: Green Biologics Place: Oxfordshire, United Kingdom Sector: Biomass, Renewable Energy Product: Oxfordshire-based industrial biotech...

  17. Global Forest Resource Assessment | Open Energy Information

    Open Energy Info (EERE)

    Assessment 2010 (FRA 2010) covers all seven thematic elements of sustainable forest management: Extent of forest resources Forest biological diversity Forest health and...

  18. South Atlantic OCS area living marine resources study. Volume II: an investigation of live bottom habitats north of Cape Fear, North Carolina. Final report

    SciTech Connect (OSTI)

    Not Available

    1981-10-01

    The major objectives of this study were to (1) characterize benthic and nektonic communities associated with representative live bottom habitats on the continental shelf of the South Atlantic Bight, and (2) evaluate factors which might influence these communities, particularly the potential for impact by offshore oil and gas activities. The report describes three study sites at the edge of the continental shelf in a 55-100m depth zone, near Cape Fear, North Carolina.

  19. OTEC environmental biological oceanographic program

    SciTech Connect (OSTI)

    Hartwig, E.O.

    1981-07-01

    One of the major goals of the OTEC biological field measurement program is to assess the effect of OTEC operations on the environment. Prior understanding of the natural variability of the tropical oceanic plankton community is the most important method for determining changes due to operation of an OTEC plant. The spatial and temporal patterns of the plankton community in terms of absolute number, biomass and species composition have been investigated at potential OTEC sites. Considerable data exist which document the changes with depth of all three measurements. Diel fluctuations in number and species composition have been studied at one site. While horizontal and seasonal patterns of variability likely exist at all sites, they are subtle and remain somewhat unclear. Attempts are now being made to determine the overall trophic structure of the plankton community at these sites using these data, gut content analysis, and information already in the literature.

  20. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect (OSTI)

    Galitski, Timothy P.

    2008-04-01

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  1. Cassini data assessment report

    SciTech Connect (OSTI)

    1998-08-01

    On October 15, 1997, the Cassini spacecraft was launched from Cape Canaveral Air Station (CCAS) and is now on its way to the planet Saturn. The functional support provided to NASA by DOE included the Advance Launch Support Group (ALSG). If there had been a launch anomaly, the ALSG would have provided a level of radiological emergency response support adequate to transition into a Federal Radiological Monitoring and Assessment Center (FRMAC). Additional functional radiological emergency response support, as part of the ALSG, included the: (1) Aerial Measurement System (AMS); (2) Atmospheric Release Advisory Capability (ARAC); (3) Geographic Information System (GIS); (4) Emergency Response Data System (ERDS); (5) Radiation Emergency Assistance Center and Training Site (REAC/TS); (6) Field monitoring and sampling; (7) Radioanalysis via RASCAL; (8) Source recovery; and (9) Neutron dosimetry and communications support. This functional support provided the capability to rapidly measure and assess radiological impacts from a launch anomaly. The Radiological Control Officer (RCO) on KSC established a Radiological Control Center (RADCC) as the focal point for all on-site and off-site radiological data and information flow. Scientists and radiological response personnel located at the RADCC managed the field monitoring team on the KSC/CCAS federal properties. Off-site radiological emergency response activities for all public lands surrounding the KSC/CCAS complex were coordinated through the Off-site ALSG located at the National Guard Armory in Cocoa, Florida. All of the in situ measurement data of good quality gathered during the dry run, the first launch attempt and the launch day are listed in this document. The RASCAL analysis results of the air filters and impactor planchets are listed.

  2. Plant biology research and training for the 21st century

    SciTech Connect (OSTI)

    Kelly, K.

    1992-01-01

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  3. Plant biology research and training for the 21st century

    SciTech Connect (OSTI)

    Kelly, K.

    1992-12-31

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  4. Biological particle identification apparatus

    DOE Patents [OSTI]

    Salzman, Gary C.; Gregg, Charles T.; Grace, W. Kevin; Hiebert, Richard D.

    1989-01-01

    An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

  5. BIOLOGICAL IRRADIATION FACILITY

    DOE Patents [OSTI]

    McCorkle, W.H.; Cern, H.S.

    1962-04-24

    A facility for irradiating biological specimens with neutrons is described. It includes a reactor wherein the core is off center in a reflector. A high-exposure room is located outside the reactor on the side nearest the core while a low-exposure room is located on the opposite side. Means for converting thermal neutrons to fast neutrons are movably disposed between the reactor core and the high and low-exposure rooms. (AEC)

  6. Report of The Structural Biology Subcommittee of The Biological and

    Office of Science (SC) Website

    Environmental Research Advisory Committee | U.S. DOE Office of Science (SC) Report of The Structural Biology Subcommittee of The Biological and Environmental Research Advisory Committee Biological and Environmental Research Advisory Committee (BERAC) BERAC Home Meetings Members Charges/Reports Current BERAC Charges Archive of BERAC Reports Charter .pdf file (135KB) BER Committees of Visitors Federal Advisory Committees BER Home Charges/Reports Report of The Structural Biology Subcommittee of

  7. Abengoa Mojave Final Biological Opinion

    Broader source: Energy.gov [DOE]

    Biological Opinion on Mojave Solar, LLC's Mojave Solar Project, San Bernardino County, California (8-8-11-F-3)

  8. The acquisition of dangerous biological materials :

    SciTech Connect (OSTI)

    Aceto, Donato Gonzalo; Astuto-Gribble, Lisa M.; Gaudioso, Jennifer M.

    2007-11-01

    Numerous terrorist organizations have openly expressed interest in producing and deploying biological weapons. However, a limiting factor for many terrorists has been the acquisition of dangerous biological agents, as evidenced by the very few successful instances of biological weapons use compared to the number of documented hoaxes. Biological agents vary greatly in their ability to cause loss of life and economic damage. Some agents, if released properly, can kill many people and cause an extensive number of secondary infections; other agents will sicken only a small number of people for a short period of time. Consequently, several biological agents can potentially be used to perpetrate a bioterrorism attack but few are likely capable of causing a high consequence event. It is crucial, from a US national security perspective, to more deeply understand the likelihood that terrorist organizations can acquire the range of these agents. Few studies have attempted to comprehensively compile the technical information directly relevant to the acquisition of dangerous bacteria, viruses and toxins. In this report, technical fact sheets were assembled for 46 potentially dangerous biological agents. Much of the information was taken from various research sources which could ultimately and significantly expedite and improve bioterrorism threat assessments. By systematically examining a number of specific agent characteristics included in these fact sheets, it may be possible to detect, target, and implement measures to thwart future terrorist acquisition attempts. In addition, the information in these fact sheets may be used as a tool to help laboratories gain a rudimentary understanding of how attractive a method laboratory theft is relative to other potential acquisition modes.

  9. Elements in biological AMS

    SciTech Connect (OSTI)

    Vogel, J.S.; McAninch, J.; Freeman, S.

    1996-08-01

    AMS (Accelerator Mass Spectrometry) provides high detection sensitivity for isotopes whose half-lives are between 10 years and 100 million years. {sup 14}C is the most developed of such isotopes and is used in tracing natural and anthropogenic organic compounds in the Earth`s biosphere. Thirty-three elements in the main periodic table and 17 lanthanides or actinides have long lived isotopes, providing potential tracers for research in elemental biochemistry. Overlap of biologically interesting heavy elements and possible AMS tracers is discussed.

  10. Environmental Impacts of Wind Power Development on the Population Biology

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Greater Prairie-Chickens | Department of Energy Impacts of Wind Power Development on the Population Biology of Greater Prairie-Chickens Environmental Impacts of Wind Power Development on the Population Biology of Greater Prairie-Chickens This report summarizes the results of a seven-year, DOE-funded research project, conducted by researchers from Kansas State University and the National Wind Coordinating Collaborative, to assess the effects of wind energy development in Kansas on the

  11. Guidelines to improve airport preparedness against chemical and biological terrorism.

    SciTech Connect (OSTI)

    Edwards, Donna M.; Price, Phillip N.; Gordon, Susanna P.; Gadgil, Ashok

    2005-05-01

    Guidelines to Improve Airport Preparedness Against Chemical and Biological Terrorism is a 100-page document that makes concrete recommendations on improving security and assessing vulnerable areas and helps its readers understand the nature of chemical and biological attacks. The report has been turned over to Airports Council International (ACI) and the American Association of Airport Executives (AAAE), two organizations that together represent the interests of thousands of airport personnel and facilities in the U.S. and around the world.

  12. Office of Enterprise Assessments Targeted Review of Work Planning and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Control and Biological Safety at the Los Alamos National Laboratory - December 2015 | Department of Energy Enterprise Assessments Targeted Review of Work Planning and Control and Biological Safety at the Los Alamos National Laboratory - December 2015 Office of Enterprise Assessments Targeted Review of Work Planning and Control and Biological Safety at the Los Alamos National Laboratory - December 2015 December 2015 Review of Work Planning and Control and Biological Safety at the Los Alamos

  13. Plant Vascular Biology 2010

    SciTech Connect (OSTI)

    Ding, Biao

    2014-11-17

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  14. Biological Applications of Synchrotron Radiation:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Welcome to the Biological and Environmental Research Abstracts Database The U.S. Department of Energy's Office of Biological and Environmental Research (BER) conducts research in the areas of Climate and Environmental Sciences and Biological Systems Science. This database contains abstracts of research projects supported by the program. Work was performed at DOE Laboratories as well as at nearly 300 universities and other research institutions. This is a historical database that includes the

  15. Biological Safety | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Select Agents Inspection Report: IG-0681, Concerns Regarding a Non-Viable (Dead) "Anthrax Sport" Research Project at the Oak Ridge National Laboratory Inspection ...

  16. Concord Cape Prototype

    SciTech Connect (OSTI)

    2010-07-09

    This case study describes a house that is designed to achieve an 87% reduction in source energy use when compared to the 2009 Building America Benchmark, and features high-R walls, roof, and foundation along with a high efficiency mechanical system.

  17. Office of Enterprise Assessments Targeted Review of Work Planning...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Control and Biological Safety at the Los Alamos National Laboratory - December 2015 Office of Enterprise Assessments Targeted Review of Work Planning and Control and ...

  18. Energy from biological processes

    SciTech Connect (OSTI)

    Not Available

    1980-07-01

    This assessment responds to a request by the Senate Committee on Commerce, Science, and Transportation for an evaluation of the energy potential of various sources of plant and animal matter (biomass). This report complements an earlier OTA report on the Application of Solar Technology to Today's Energy Needs in evaluating the major solar energy resources available to the United States. The findings also will serve as part of the material to be used in an upcoming OTA assessment of synthetic fuels for transportation. This volume presents analyses of prominent biomass issues, summaries of four biomass fuel cycles, a description of biomass' place in two plausible energy futures, and discussions of policy options for promoting energy from biomass. The four fuel cycles - wood, alcohol fuels, grasses and crop residues, and animal wastes - were chosen because of their near- to mid-term energy potential and because of the public interest in them. A second volume presents technical analyses of the resource base, conversion technologies, and end uses that provide a basis for the discussion in this volume. Also included in Volume II are various unconventional approaches to bioenergy production as well as the use of biomass to produce chemicals.

  19. INTERNAL ASSESSMENT COVER SHEETS, IB Biology I/II

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Report) | SciTech Connect INTEGRATED GENOME-BASED STUDIES OF SHEWANELLA ECOPHYSIOLOGY Citation Details In-Document Search Title: INTEGRATED GENOME-BASED STUDIES OF SHEWANELLA ECOPHYSIOLOGY This project had as its goals the understanding of the ecophysiology of the genus Shewanella using various genomics approaches. As opposed to other programs involving Shewanella, this one branched out into the various areas in which Shewanella cells are active, and included both basic and applied studies.

  20. Hydro Review: Computational Tools to Assess Turbine Biological...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    designs to help ensure the safety of fish passing through the turbines at the Priest ... Environmental Effects of Hydrokinetic Turbines on Fish: Desktop and Laboratory Flume ...

  1. ASSESSMENT REPORT

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Its scientific programs focus on materials, neutron science, energy, high performance computing, systems biology, and national security. During fiscal year (FY) 2013,...

  2. Wind Resource and Feasibility Assessment Report for the Lummi Reservation

    SciTech Connect (OSTI)

    DNV Renewables Inc.; J.C. Brennan & Associates, Inc.; Hamer Environmental L.P.

    2012-08-31

    This report summarizes the wind resource on the Lummi Indian Reservation (Washington State) and presents the methodology, assumptions, and final results of the wind energy development feasibility assessment, which included an assessment of biological impacts and noise impacts.

  3. ionic liquids biological-ly derived from lignin and hemicellulose

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    biological-ly derived from lignin and hemicellulose - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste

  4. Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects from

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Development | Department of Energy Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects from Development Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects from Development Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects from Development PDF icon PNNL-18567.pdf More Documents & Publications EA-1772: Final Environmental Assessment EA-1772: Finding of No Significant Impact EIS-0521: Notice of Intent to Prepare an Environmental Impact

  5. Biological Science | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... When Wellington Muchero got a part-time job in a plant molecular biology lab as a college student, there was no turning back. Learn how this quantitative geneticist advances ...

  6. Synthetic biology and crop engineering

    Broader source: Energy.gov [DOE]

    Breakout Session 2: Frontiers and Horizons Session 2-A: Synthetic Biology and the Promise of Biofuels Jonathan Burbaum, Program Director, Department of Energy, Office of Science, ARPA–E

  7. Information resources and the correlation of response patterns between biological end points

    SciTech Connect (OSTI)

    Malling, H.V.; Wassom, J.S.

    1990-12-31

    This paper focuses on the analysis of information for mutagenesis, a biological end point that is important in the overall process of assessing possible adverse health effects from chemical exposure. 17 refs.

  8. Assessment Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... SCADA Assessments Since 1999, Sandia has conducted numerous assessments of operational systems in hydroelectric dams; water treatment systems; electric power transmission, ...

  9. Renewable Hydrogen Production from Biological Systems

    Broader source: Energy.gov (indexed) [DOE]

    Hydrogen Production from Biological Systems Matthew Posewitz Colorado School of Mines DOE Biological Hydrogen Production Workshop September 24 th , 2013 H 2 production PSIIPSI...

  10. Autofermentative Biological Hydrogen Production by Cyanobacteria...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon bioh2workshopdismukes.pdf More Documents & Publications 2013 Biological Hydrogen Production Workshop Summary Report Renewable Hydrogen Production from Biological ...

  11. Air monitoring and detection of chemical and biological agents

    SciTech Connect (OSTI)

    Leonelli, J.; Althouse, M.L.

    1999-06-01

    This volume contains the proceedings of SPIE`s remote sensing symposium which was held November 2--3, 1998 in Boston, Massachusetts. Topics of discussion include the following: system simulations, atmospheric modeling, and performance prediction studies of chemical warfare remote sensing technologies; ultraviolet laser-induced fluorescence and aerosol detection methods for remote sensing of biological warfare agents; passive detection methods for remote detection of chemical warfare agents; and lidar-based system performance assessments, demonstrations, and new concepts for chemical warfare/biological warfare detection.

  12. Systems biology approach to bioremediation

    SciTech Connect (OSTI)

    Chakraborty, Romy; Wu, Cindy H.; Hazen, Terry C.

    2012-06-01

    Bioremediation has historically been approached as a ‘black box’ in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Finally, understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ‘black box’.

  13. SC e-journals, Biology/Genetics

    Office of Scientific and Technical Information (OSTI)

    Biology/Genetics ACM Transactions on Applied Perception (TAP) ACS Chemical Biology ACS Synthetic Biology Acta Biotheoretica Acta Neuropathologica Advances in Bioinformatics - OAJ Advances in Health Sciences Education Agriculture and Human Values Agroforestry Systems American Journal of Agricultural and Biological Science - OAJ American Journal of Medical Genetics Amino Acids Analyst Analytical and Bioanalytical Chemistry Analytical Biochemistry Anatomical Record, The Anatomy and Embryology

  14. EA-1494: Final Environmental Assessment | Department of Energy

    Office of Environmental Management (EM)

    4: Final Environmental Assessment EA-1494: Final Environmental Assessment Activities Using Biological Simulants and Releases of Chemicals at the Nevada Test Site This Environmental Assessment (EA) documents an analysis of the potential effects of a proposal by the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO), to conduct tests and experiments involving the release of biological simulants and low concentrations of chemicals at various

  15. Artificial photosynthesis combines biology with technology for...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Artificial photosynthesis combines biology with technology for sustainable energy ... photosynthetic net primary production (NPP) to support our GDP and nutrition. ...

  16. Autofermentative Biological Hydrogen Production by Cyanobacteria |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Autofermentative Biological Hydrogen Production by Cyanobacteria Autofermentative Biological Hydrogen Production by Cyanobacteria Presentation by Charles Dismukes, Rutgers University, at the Biological Hydrogen Production Workshop held September 24-25, 2013, at the National Renewable Energy Laboratory in Golden, Colorado. PDF icon bio_h2_workshop_dismukes.pdf More Documents & Publications 2013 Biological Hydrogen Production Workshop Summary Report Renewable Hydrogen

  17. Semiconductor Nanocrystals for Biological Imaging

    SciTech Connect (OSTI)

    Fu, Aihua; Gu, Weiwei; Larabell, Carolyn; Alivisatos, A. Paul

    2005-06-28

    Conventional organic fluorophores suffer from poor photo stability, narrow absorption spectra and broad emission feature. Semiconductor nanocrystals, on the other hand, are highly photo-stable with broad absorption spectra and narrow size-tunable emission spectra. Recent advances in the synthesis of these materials have resulted in bright, sensitive, extremely photo-stable and biocompatible semiconductor fluorophores. Commercial availability facilitates their application in a variety of unprecedented biological experiments, including multiplexed cellular imaging, long-term in vitro and in vivo labeling, deep tissue structure mapping and single particle investigation of dynamic cellular processes. Semiconductor nanocrystals are one of the first examples of nanotechnology enabling a new class of biomedical applications.

  18. Consequence Assessment

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-08-21

    This volume focuses on the process of performing timely initial assessments necessary to support critical first decisions and the continuous process of refining those initial assessments as more information and resources become available. Canceled by DOE G 151.1-4.

  19. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2006-01-24

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

  20. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2013-10-15

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  1. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2010-03-23

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  2. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2010-03-23

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  3. Assessing How Renewables Affect Water Used for Thermoelectric Cooling |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    U.S. DOE Office of Science (SC) Assessing How Renewables Affect Water Used for Thermoelectric Cooling Biological and Environmental Research (BER) BER Home About Research Facilities Science Highlights Searchable Archive of BER Highlights External link Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) Community Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000

  4. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.: Davis, J.C.; Stanker, L.H.

    1993-05-11

    A method is disclosed of quantifying molecules in biological substances, comprising: selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere; preparing a long-lived radioisotope labeled reactive chemical specie; administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system; allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host; isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources; converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation; and measuring the radioisotope concentration in the material by means of direct isotopic counting.

  5. Study of biological processes on the US South Atlantic slope and rise. Phase 1: Benthic characterization. Volume 1. Executive Summary

    SciTech Connect (OSTI)

    Blake, J.A.; Hecker, B.; Grassle, J.F.; Maciolek-Blake, N.; Brown, B.

    1985-06-01

    Concerns about the potential effects of oil and gas exploration on the U.S. Continental Slope and Rise led to the initiation of a deep-sea characterization study off North Carolina. The program included a seasonal characterization of biological and surficial geological properties at a limited number of slope and rise sites, with special emphasis on areas of high oil industry interest. A five-station transect was established off Cape Lookout in depths of 600 m, 1000 m, 1500 m, 2000 m and 3000 m. A rich and highly diverse benthic infauna was discovered, with a large percentage of the 877 species being new to science. Faunal density was highest on the upper slope (600 m) and lowest on the continental rise (3000 m). Species diversity values were all higher than 6.0, indicating a very diverse fauna, with the highest values at 3000 m. Foraminiferan tests comprised most of the sand fraction. Hydrographic data indicated some intrusion of colder water on the upper slope benthos from deeper water.

  6. Breaking the Biological Barriers to Cellulosic Ethanol, June...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 Breaking the Biological Barriers to Cellulosic...

  7. Procedure for developing biological input for the design, location, or modification of water-intake structures

    SciTech Connect (OSTI)

    Neitzel, D.A.; McKenzie, D.H.

    1981-12-01

    To minimize adverse impact on aquatic ecosystems resulting from the operation of water intake structures, design engineers must have relevant information on the behavior, physiology and ecology of local fish and shellfish. Identification of stimulus/response relationships and the environmental factors that influence them is the first step in incorporating biological information in the design, location or modification of water intake structures. A procedure is presented in this document for providing biological input to engineers who are designing, locating or modifying a water intake structure. The authors discuss sources of stimuli at water intakes, historical approaches in assessing potential/actual impact and review biological information needed for intake design.

  8. Towards a Semantic Lexicon for Biological Language Processing

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Verspoor, Karin

    2005-01-01

    This paper explores the use of the resources in the National Library of Medicine's Unified Medical Language System (UMLS) for the construction of a lexicon useful for processing texts in the field of molecular biology. A lexicon is constructed from overlapping terms in the UMLS SPECIALIST lexicon and the UMLS Metathesaurus to obtain both morphosyntactic and semantic information for terms, and the coverage of a domain corpus is assessed. Over 77% of tokens in the domain corpus are found in the constructed lexicon, validating the lexicon's coverage of the most frequent terms in the domain and indicating that the constructedmore » lexicon is potentially an important resource for biological text processing.« less

  9. Risk Assessment

    Broader source: Energy.gov [DOE]

    A set of issues that state and local governments should carefully consider, with the goal of helping them assess and anticipate solutions for some worst case or unfortunate case scenarios as they...

  10. Environmental Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    728D Environmental Assessment Integrated Vegetation Management on the Hanford Site, Richland, Washington U.S. Department of Energy Richland Operations Office Richland, Washington 99352 Approved for Public Release; Further Disseminat ion Uillimited June 2011 DOE/EA-1728D June 2011 1 2 3 4 5 6 This page intentionally left blank. 7 8 U.S. Department of Energy DOE/EA-1728D Draft Environmental Assessment iii June 2011 CONTENTS 1 2 1.0 INTRODUCTION

  11. Environmental Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ASSESSMENT (EA) FOR THE RECONSTRUCTION OF THE SOUTH ACCESS ROAD (CR 802) IN SUPPORT OF THE DEPARTMENT OF ENERGY, WASTE ISOLATION PILOT PLANT (WIPP) IN EDDY COUNTY, NEW MEXICO NEPA #: DOI-BLM-NM-P020-2010-0011-EA PREPARED IN COOPERATION WITH: DEPARTMENT OF ENERGY CARLSBAD FIELD OFFICE P. O. BOX 2078 CARLSBAD, NM 88221-2078 PREPARED BY: OWEN W. LOFTON SUPERVISORY MULTI RESOURCES SPECIALIST BUREAU OF LAND MANAGEMENT CARLSBAD FIELD OFFICE 620 EAST GREENE CARLSBAD, NM 88220 ENVIRONMENTAL ASSESSMENT

  12. RADIOLOGICAL ASSESSMENT

    Office of Legacy Management (LM)

    ASSESSMENT and STABILIZATION' SCENARIOS PARRERSBURG,'W. VA. SITE FEBRUARY 1980 M. CARSON J. COFFMAN N. MANDELTORT, ! Division of Nuclear Service Operations Chem-Nuclear\ Systems, Inc. 240 Stoneridge Dr., Suite 100 Columbia, South Carolina 29210 Prepared for AMAX Specialty Hetals Corporation One Greenwich Plaza Greenwich, Connecticut 06830 During July' 1978, Chem-Nuclear Systems, Inc. (CNSI) began an assessment program for AMAX Specialty Metals Corp."(AMAX) u to locate, quantify, and

  13. Sleep Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sleep Assessment 1 | Thank you for taking the time to complete this extensive form. Sleep disturbances and/or fatigue are most often the result of many factors. In order to best treat your condition we need to understand your symptoms and history. Please bring your completed assessment form to your appointment. To schedule an appointment please call 505 844-HBES (4237). Name: Employee ID#: Date: Male Female Age: Health Plan : United BCBSNM Other: Referred by: Sleep and Health History In general,

  14. Electrostatic thin film chemical and biological sensor

    DOE Patents [OSTI]

    Prelas, Mark A.; Ghosh, Tushar K.; Tompson, Jr., Robert V.; Viswanath, Dabir; Loyalka, Sudarshan K.

    2010-01-19

    A chemical and biological agent sensor includes an electrostatic thin film supported by a substrate. The film includes an electrostatic charged surface to attract predetermined biological and chemical agents of interest. A charge collector associated with said electrostatic thin film collects charge associated with surface defects in the electrostatic film induced by the predetermined biological and chemical agents of interest. A preferred sensing system includes a charge based deep level transient spectroscopy system to read out charges from the film and match responses to data sets regarding the agents of interest. A method for sensing biological and chemical agents includes providing a thin sensing film having a predetermined electrostatic charge. The film is exposed to an environment suspected of containing the biological and chemical agents. Quantum surface effects on the film are measured. Biological and/or chemical agents can be detected, identified and quantified based on the measured quantum surface effects.

  15. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    Welcome to the Biological and Environmental Research Abstracts Database The U.S. Department of Energy's Office of Biological and Environmental Research (BER) conducts research in the areas of Climate and Environmental Sciences and Biological Systems Science. This database contains abstracts of research projects supported by the program. Work was performed at DOE Laboratories as well as at nearly 300 universities and other research institutions. This is a historical database that includes the

  16. Method for photo-altering a biological system to improve biological effect

    DOE Patents [OSTI]

    Hill, Richard A. (Irvine, CA); Doiron, Daniel R. (Santa Ynez, CA); Crean, David H. (Santa Barbara, CA)

    2000-08-01

    Photodynamic therapy is a new adjunctive therapy for filtration surgery that does not use chemotherapy agents or radiation, but uses pharmacologically-active sensitizing compounds to produce a titratable, localized, transient, post operative avascular conjunctiva. A photosensitizing agent in a biological system is selectively activated by delivering the photosensitive agent to the biological system and laser activating only a spatially selected portion of the delivered photosensitive agent. The activated portion of the photosensitive agent reacts with the biological system to obtain a predetermined biological effect. As a result, an improved spatial disposition and effectuation of the biological effect by the photosensitive agent in the biological system is achieved.

  17. A brief history of the Biology Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Complex Most of the "Biology" buildings were constructed in early 1945 and were built as expansion capability for the uranium preparation operations being conducted across the...

  18. Molecular biology of signal transduction in plants

    SciTech Connect (OSTI)

    Not Available

    1991-01-01

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  19. Biological and Environmental Research Advisory Committee (BERAC...

    Office of Science (SC) Website

    Sharlene Weatherwax .pdf file (768KB) Office of Biological and Environmental Research Update Gary Geernaert .pdf file (5.8MB) Climate and Environmental Sciences Division Update ...

  20. Developing Biological Specifications for Fish Friendly Turbines

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Specifications for Fish Friendly Turbines The U.S. Department of Energy's ... which environmen- tal attributes, such as entrainment survival for fish, are emphasized. ...

  1. Developing Biological Specifications for Fish Friendly Turbines

    Broader source: Energy.gov [DOE]

    This factsheet explains studies conducted in a highly reproducible manner to examine the biological effects to fish exposed to a shear environment in the laboratory.

  2. 2013 Biological Hydrogen Production Workshop Summary Report ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    November 2013 summary report for the 2013 Biological Hydrogen Production Workshop. PDF icon bioh2workshopfinalreport.pdf More Documents & Publications The Hydrogen Program at ...

  3. Repurposing the translation apparatus for synthetic biology ...

    Office of Scientific and Technical Information (OSTI)

    Journal Name: Current Opinion in Chemical Biology Additional Journal Information: Journal ... Publisher: Elsevier Sponsoring Org: USDOE Advanced Research Projects Agency - Energy ...

  4. Enterprise Assessments Emergency Management Assessment of the...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Emergency Management Assessment of the Waste Isolation Pilot Plant - April 2016 Enterprise Assessments Emergency Management Assessment of the Waste Isolation Pilot Plant - April ...

  5. Technology Assessment

    Energy Savers [EERE]

    Roll to Roll (R2R) Processing 1 Technology Assessment 2 3 Contents 4 1. Introduction to the Technology/System ............................................................................................... 2 5 1.1. Introduction to R2R Processing..................................................................................................... 2 6 1.2. R2R Processing Mechanisms ......................................................................................................... 3 7 2.

  6. Sharpening Our Tools: Algal Biology Toolbox Workshop

    Broader source: Energy.gov [DOE]

    The Bioenergy Technologies Office (BETO) will host the Algal Biology Toolbox Workshop on May 24-25, 2016, in San Diego, California. Because biological productivity is a key driver for the economic viability of algae-based biofuels, improving on the performance of native strains is a critical element of the research efforts funded by the Advanced Algal Systems program at BETO.

  7. Ninth International Workshop on Plant Membrane Biology

    SciTech Connect (OSTI)

    Not Available

    1993-12-31

    This report is a compilation of abstracts from papers which were discussed at a workshop on plant membrane biology. Topics include: plasma membrane ATP-ases; plant-environment interactions, membrane receptors; signal transduction; ion channel physiology; biophysics and molecular biology; vaculor H+ pumps; sugar carriers; membrane transport; and cellular structure and function.

  8. Cape Wind | Open Energy Information

    Open Energy Info (EERE)

    02116 Region: Greater Boston Area Sector: Wind energy Product: Developing America's first offshore wind farm Website: www.capewind.org Coordinates: 42.3511372, -71.0703224...

  9. ASSESSMENT REPORT

    Energy Savers [EERE]

    & Wilcox Technical Services Pantex LLC During Fiscal Year 2013 Through June 30, 2014, Under Department of Energy Contract No. DE-AC54-00AL66620 OAI-V-16-04 February 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 February 12, 2016 MEMORANDUM FOR THE MANAGER, NNSA PRODUCTION OFFICE FROM: David Sedillo, Director Western Audits Division Office of Inspector General SUBJECT: INFORMATION: Assessment Report on

  10. Endogenous Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Endogenous Assessment of the Capacity Value of Solar PV in Generation Investment Planning Studies Francisco D. Munoz, Member, IEEE, and Andrew D. Mills Abstract-There exist several different reliability- and approximation-based methods to determine the contribution of solar resources towards resource adequacy. However, most of these approaches require knowing in advance the installed capacities of both conventional and solar generators. This is a complication since generator capacities are

  11. Performance Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Performance assessment (PA) is defined in the United States by the Environmental Protection Agency (EPA) and the Nuclear Regulatory Commission (NRC) regulations as a process to be used in estimating the long-term performance of deep geologic disposal sites for high-level and transuranic radioactive waste. Although specific regulatory requirements differ for individual projects (e.g., the Waste Isolation Pilot Plant and the potential repository at Yucca Mountain), the overall approach to PA is

  12. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.; Davis, J.C.

    1994-12-27

    Disclosed is a method of quantifying molecules in biological substances comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system, d. allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host, e. isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources, f. converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in the material by means of direct isotopic counting. 5 figures.

  13. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, Kenneth W.; Vogel, John S.; Felton, James S.; Gledhill, Barton L.; Davis, Jay C.; Stanker, Larry H.

    1993-05-11

    Disclosed is a method of quantifying molecules in biological substances, comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering said chemical specie to said biological host in doses sufficiently low to avoid significant overt damage to the biological system thereof, d. allowing a period of time to elapse sufficient for dissemination and interaction of said chemical specie with said host throughout said biological system of said host, e. isolating a reacted fraction of the biological substance from said host in a manner sufficient to avoid contamination of said substance from extraneous sources, f. converting said fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in said material by means of direct isotopic counting.

  14. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, Kenneth W.; Vogel, John S.; Felton, James S.; Gledhill, Barton L.; Davis, Jay C.

    1994-01-01

    Disclosed is a method of quantifying molecules in biological substances comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering said chemical specie to said biological host in doses sufficiently low to avoid significant overt damage to the biological system thereof, d. allowing a period of time to elapse sufficient for dissemination and interaction of said chemical specie with said host throughout said biological system of said host, e. isolating a reacted fraction of the biological substance from said host in a manner sufficient to avoid contamination of said substance from extraneous sources, f. converting said fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in said material by means of direct isotopic counting.

  15. Role of basic ecological knowledge in environmental assessment

    SciTech Connect (OSTI)

    Hildebrand, S.G.; Barnthouse, L.W.; Suter, G.W.

    1984-01-01

    The role of basic ecological knowledge in environmental impact assessment was examined. The focus was primarily on the NEPA process. Experience in population biology and ecosystem studies is discussed, the successes and limits of applicability are highlighted, and implications for long-term research needs are identified. Current attempts to develop a national assessment of acid deposition impacts are reviewed. 48 refs. (ACR)

  16. EA-1958: Final Environmental Assessment | Department of Energy

    Energy Savers [EERE]

    8: Final Environmental Assessment EA-1958: Final Environmental Assessment Future Development in Proximity to the William R. Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington This EA evaluates the potential environmental impacts of constructing and operating these proposed facilities and/or additions and proposed infrastructure, including impacts on land use, air quality, water quality, geological resources, biological resources,

  17. Micro/nanofabricated environments for synthetic biology

    SciTech Connect (OSTI)

    Collier, Pat [ORNL; Simpson, Michael L [ORNL

    2011-01-01

    A better understanding of how confinement, crowding and reduced dimensionality modulate reactivity and reaction dynamics will aid in the rational and systematic discovery of functionality in complex biological systems. Artificial micro- and nanofabricated structures have helped elucidate the effects of nanoscale spatial confinement and segregation on biological behavior, particularly when integrated with microfluidics, through precise control in both space and time of diffusible signals and binding interactions. Examples of nanostructured interfaces for synthetic biology include the development of cell-like compartments for encapsulating biochemical reactions, nanostructured environments for fundamental studies of diffusion, molecular transport and biochemical reaction kinetics, and regulation of biomolecular interactions as functions of micro- and nanofabricated topological constraints.

  18. ASSESSMENT REPORT

    Energy Savers [EERE]

    Alliance for Sustainable Energy LLC During Fiscal Years 2012 and 2013 Under Department of Energy Contract No. DE-AC36-08GO28308 OAI-V-16-06 March 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 March 11, 2016 MEMORANDUM FOR THE DIRECTOR, GOLDEN FIELD OFFICE FROM: Jack Rouch Deputy Assistant Inspector General for Audits Office of Inspector General SUBJECT: INFORMATION: Assessment Report on "Audit Coverage

  19. ASSESSMENT REPORT

    Energy Savers [EERE]

    Stanford University During Fiscal Years 2012 and 2013 Under Department of Energy Contract No. DE-AC02-76SF00515 OAS-V-15-04 September 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 September 21, 2015 MEMORANDUM FOR THE MANAGER, SLAC SITE OFFICE FROM: David Sedillo, Director Western Audits Division Office of Inspector General SUBJECT: INFORMATION: Assessment Report: "Audit Coverage of Cost Allowability for

  20. ASSESSMENT REPORT

    Energy Savers [EERE]

    Brookhaven Science Associates LLC During Fiscal Years 2012 and 2013 Under Department of Energy Contract No. DE-AC02-98CH10886 OAI-V-16-03 January 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 January 19, 2016 MEMORANDUM FOR THE MANAGER, BROOKHAVEN SITE OFFICE FROM: Jack Rouch, Director Central Audits Division Office of Inspector General SUBJECT: INFORMATION: Assessment Report: "Audit Coverage of Cost

  1. ASSESSMENT REPORT

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ASSESSMENT REPORT Audit Coverage of Cost Allowability for National Security Technologies LLC During Fiscal Years 2012 Through 2014 Under Department of Energy Contract No. DE-AC52-06NA25946 OAI-V-16-07 April 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 April 12, 2016 MEMORANDUM FOR THE MANAGER, NEVADA FIELD OFFICE FROM: David Sedillo Deputy Assistant Inspector General for Audits and Inspections Office of

  2. 2013 Biological Hydrogen Production Workshop Summary Report

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and the implications for both in vivo and in vitro activity were discussed. "Self-repair" is often cited as an advantage of biological systems, and some of the mechanisms...

  3. Biological denitrification of high concentration nitrate waste

    DOE Patents [OSTI]

    Francis, Chester W.; Brinkley, Frank S.

    1977-01-01

    Biological denitrification of nitrate solutions at concentrations of greater than one kilogram nitrate per cubic meter is accomplished anaerobically in an upflow column having as a packing material a support for denitrifying bacteria.

  4. Algal Biology Program at Los Alamos

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Algal Biology Program at Los Alamos gets a star October 11, 2011 LOS ALAMOS, New Mexico, October 11, 2011-Richard Sayre, one of the nation's top specialists in algae and...

  5. Renewable Hydrogen Production from Biological Systems

    Broader source: Energy.gov [DOE]

    Presentation by Matthew Posewitz, Colorado School of Mines, at the Biological Hydrogen Production Workshop held September 24-25, 2013, at the National Renewable Energy Laboratory in Golden, Colorado.

  6. Genetics and molecular biology of breast cancer

    SciTech Connect (OSTI)

    King, M.C.; Lippman, M.

    1992-12-31

    This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

  7. Frontiers of NMR in Molecular Biology

    SciTech Connect (OSTI)

    1999-08-25

    NMR spectroscopy is expanding the horizons of structural biology by determining the structures and describing the dynamics of blobular proteins in aqueous solution, as well as other classes of proteins including membrane proteins and the polypeptides that form the aggregates diagnostic of prion and amyloid diseases. Significant results are also emerging on DNA and RNA oligomers and their complexes with proteins. This meeting focused attention on key structural questions emanating from molecular biology and how NMR spectroscopy can be used to answer them.

  8. Molecular Mechanism of Biological Proton Transport

    SciTech Connect (OSTI)

    Pomes, R.

    1998-09-01

    Proton transport across lipid membranes is a fundamental aspect of biological energy transduction (metabolism). This function is mediated by a Grotthuss mechanism involving proton hopping along hydrogen-bonded networks embedded in membrane-spanning proteins. Using molecular simulations, the authors have explored the structural, dynamic, and thermodynamic properties giving rise to long-range proton translocation in hydrogen-bonded networks involving water molecules, or water wires, which are emerging as ubiquitous H{sup +}-transport devices in biological systems.

  9. Biological Air Emissions Control | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Air Emissions Control Biological Air Emissions Control Innovative Technology Enables Low-Cost, Energy-Efficient Treatment of Industrial Exhaust Streams Air quality standards are becoming more stringent for the U.S. wood products industry. Emissions of volatile organic compounds (VOCs) and hazardous air pollutants (HAPs) (including methanol, formaldehyde, acetylaldehyde, and acrolein) during production of wood products must be tightly controlled. Conventional VOCs and HAPs emission

  10. Biological Monitoring and Abatement Program for the Oak Ridge K-25 Site

    SciTech Connect (OSTI)

    Kszos, L.A.; Adams, S.M.; Ashwood, T.L.; Blaylock, B.G.; Greeley, M.S.; Loar, J.M.; Peterson, M.J.; Ryon, M.G.; Smith, J.G.; Southworth, G.R.; Hinzman, R.L.; Shoemaker, B.A.

    1993-04-01

    A proposed Biological Monitoring and Abatement Program (BMAP) for the Oak Ridge K-25 Site was prepared in December 1992 as required by the renewed National Pollutant Discharge Elimination System permit that was issued on October 1, 1992. The proposed BMAP is based on results of biological monitoring conducted from 1986 to 1992 and discussions held on November 12, 1992, between staff of Martin Marietta Energy Systems, Inc. (Oak Ridge National Laboratory and the K-25 Site), and the Tennessee Department of Environment and Conservation, Department of Energy Oversight Division. The proposed BMAP consists of four tasks that reflect different but complementary approaches to evaluating the effects of K-25 Site effluents on the ecological integrity of Mitchell Branch, Poplar Creek, and the Poplar Creek embayment of the Clinch River. These tasks include (1) ambient toxicity monitoring, (2) bioaccumulation monitoring, (3) assessment of fish health, and (4) instream monitoring of biological communities. This overall BMAP plan combines established protocols with current biological monitoring techniques to assess environmental compliance and quantify ecological recovery. The BMAP will also determine whether the effluent limits established for the K-25 Site protect the designated use of the receiving streams (Mitchell Branch, Poplar Creek, and Clinch River) for growth and propagation of fish and other aquatic life. Results obtained from this biological monitoring program will also be used to document the ecological effects (and effectiveness) of remedial actions.

  11. Synthetic Biology for Advanced Fuels (Opening Keynote Address...

    Office of Scientific and Technical Information (OSTI)

    Synthetic Biology for Advanced Fuels (Opening Keynote Address - 2010 JGI User Meeting) Citation Details In-Document Search Title: Synthetic Biology for Advanced Fuels (Opening ...

  12. Flow cytometry aids basic cell biology research and drug discovery

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Flow cytometry aids basic cell biology research and drug discovery Flow cytometry aids basic cell biology research and drug discovery Life Technologies Corporation and LANL have ...

  13. Solar Energy Education. Renewable energy activities for biology...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    biology Citation Details In-Document Search Title: Solar Energy Education. Renewable energy activities for biology You are accessing a document from the Department of Energy's ...

  14. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) ...

  15. Copy of Synthetic Biology of Novel Thermophilic Bacteria for...

    Office of Scientific and Technical Information (OSTI)

    Copy of Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of ... Citation Details In-Document Search Title: Copy of Synthetic Biology of Novel Thermophilic ...

  16. Biological and Environmental Research (BER) Homepage | U.S. DOE...

    Office of Science (SC) Website

    DISCOVERING the physical, chemical, and biological drivers of climate change. Understanding Complex Biological and Environmental Systems across many spatial and temporal scales by ...

  17. Nanojunction Sensors for the Detection of chemical and Biological...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nanojunction Sensors for the Detection of chemical and Biological Species DOE Grant ... gaps for various applications, including chemical and biological sensors, magnetoresistive ...

  18. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production Report documenting the ...

  19. UK Biotechnology and Biological Sciences Research Council | Open...

    Open Energy Info (EERE)

    Biotechnology and Biological Sciences Research Council Jump to: navigation, search Name: UK Biotechnology and Biological Sciences Research Council Place: London, United Kingdom...

  20. Detter, John C. [Los Alamos National Laboratory] Basic Biological

    Office of Scientific and Technical Information (OSTI)

    State of the Art for Autonomous Detection Systems using Genomic Sequencing Detter, John C. Los Alamos National Laboratory Basic Biological Sciences(59) Biological Science...

  1. Biological Conversion of Sugars to Hydrocarbons Technology Pathway...

    Office of Scientific and Technical Information (OSTI)

    Biological Conversion of Sugars to Hydrocarbons Technology Pathway Citation Details In-Document Search Title: Biological Conversion of Sugars to Hydrocarbons Technology Pathway ...

  2. California: Breakthrough in Algae Biology | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Breakthrough in Algae Biology California: Breakthrough in Algae Biology January 31, 2014 - 12:00am Addthis Researchers at the Scripps Institution of Oceanography at University of ...

  3. Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate...

    Office of Scientific and Technical Information (OSTI)

    Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate-Reducing Bacteria Citation Details In-Document Search Title: Genetics and Molecular Biology of Hydrogen Metabolism ...

  4. Enterprise Assessments Emergency Management Assessment of the...

    Office of Environmental Management (EM)

    ... EAL Emergency Action Level ED Emergency Director ... Emergency Management Assessment of the Waste Isolation Pilot Plant ... assessment checklist, and the emergency ...

  5. Ecological Risk Assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ecological Risk Assessments Ecological Risk Assessments Ecological risk assessment is the appraisal of potential adverse effects of exposure to contaminants on plants and animals....

  6. The Intersection of Physics and Biology

    ScienceCinema (OSTI)

    Liphardt, Jan [University of California, Berkeley, California, United States

    2010-09-01

    In April 1953, Watson and Crick largely defined the program of 20th century biology: obtaining the blueprint of life encoded in the DNA. Fifty years later, in 2003, the sequencing of the human genome was completed. Like any major scientific breakthrough, the sequencing of the human genome raised many more questions than it answered. I'll brief you on some of the big open problems in cell and developmental biology, and I'll explain why approaches, tools, and ideas from the physical sciences are currently reshaping biological research. Super-resolution light microscopies are revealing the intricate spatial organization of cells, single-molecule methods show how molecular machines function, and new probes are clarifying the role of mechanical forces in cell and tissue function. At the same time, Physics stands to gain beautiful new problems in soft condensed matter, quantum mechanics, and non-equilibrium thermodynamics.

  7. Biological Information Document, Radioactive Liquid Waste Treatment Facility

    SciTech Connect (OSTI)

    Biggs, J.

    1995-12-31

    This document is intended to act as a baseline source material for risk assessments which can be used in Environmental Assessments and Environmental Impact Statements. The current Radioactive Liquid Waste Treatment Facility (RLWTF) does not meet current General Design Criteria for Non-reactor Nuclear Facilities and could be shut down affecting several DOE programs. This Biological Information Document summarizes various biological studies that have been conducted in the vicinity of new Proposed RLWTF site and an Alternative site. The Proposed site is located on Mesita del Buey, a mess top, and the Alternative site is located in Mortandad Canyon. The Proposed Site is devoid of overstory species due to previous disturbance and is dominated by a mixture of grasses, forbs, and scattered low-growing shrubs. Vegetation immediately adjacent to the site is a pinyon-juniper woodland. The Mortandad canyon bottom overstory is dominated by ponderosa pine, willow, and rush. The south-facing slope was dominated by ponderosa pine, mountain mahogany, oak, and muhly. The north-facing slope is dominated by Douglas fir, ponderosa pine, and oak. Studies on wildlife species are limited in the vicinity of the proposed project and further studies will be necessary to accurately identify wildlife populations and to what extent they utilize the project area. Some information is provided on invertebrates, amphibians and reptiles, and small mammals. Additional species information from other nearby locations is discussed in detail. Habitat requirements exist in the project area for one federally threatened wildlife species, the peregrine falcon, and one federal candidate species, the spotted bat. However, based on surveys outside of the project area but in similar habitats, these species are not expected to occur in either the Proposed or Alternative RLWTF sites. Habitat Evaluation Procedures were used to evaluate ecological functioning in the project area.

  8. Biological cell classification by multiangle light scattering

    DOE Patents [OSTI]

    Salzman, G.C.; Crowell, J.M.; Mullaney, P.F.

    1975-06-03

    The specification is directed to an apparatus and method for detecting light scattering from a biological cell. Light, preferably from a coherent source of radiation, intercepts an individual biological cell in a stream of cells passing through the beam. Light scattered from the cell is detected at a selected number of angles between 0 and 90/sup 0/ to the longitudinal axis of the beam with a circular array of light responsive elements which produce signals representative of the intensity of light incident thereon. Signals from the elements are processed to determine the light-scattering pattern of the cell and therefrom its identity.

  9. Biology and Medicine Division: Annual report 1986

    SciTech Connect (OSTI)

    Not Available

    1987-04-01

    The Biology and Medicine Division continues to make important contributions in scientific areas in which it has a long-established leadership role. For 50 years the Division has pioneered in the application of radioisotopes and charged particles to biology and medicine. There is a growing emphasis on cellular and molecular applications in the work of all the Division's research groups. The powerful tools of genetic engineering, the use of recombinant products, the analytical application of DNA probes, and the use of restriction fragment length polymorphic DNA are described and proposed for increasing use in the future.

  10. Spectroscopic diagnostics for bacteria in biologic sample

    DOE Patents [OSTI]

    El-Sayed, Mostafa A.; El-Sayed, Ivan H.

    2002-01-01

    A method to analyze and diagnose specific bacteria in a biologic sample using spectroscopy is disclosed. The method includes obtaining the spectra of a biologic sample of a non-infected patient for use as a reference, subtracting the reference from the spectra of an infected sample, and comparing the fingerprint regions of the resulting differential spectrum with reference spectra of bacteria in saline. Using this diagnostic technique, specific bacteria can be identified sooner and without culturing, bacteria-specific antibiotics can be prescribed sooner, resulting in decreased likelihood of antibiotic resistance and an overall reduction of medical costs.

  11. Biological and Environmental Research Advisory Committee

    Office of Science (SC) Website

    March 03-04, 2014 | U.S. DOE Office of Science (SC) March 03-04, 2014 Biological and Environmental Research Advisory Committee (BERAC) BERAC Home Meetings BERAC Minutes BERAC Minutes Archive Members Charges/Reports Charter .pdf file (135KB) BER Committees of Visitors Federal Advisory Committees BER Home Meetings Biological and Environmental Research Advisory Committee March 03-04, 2014 Print Text Size: A A A FeedbackShare Page Agenda .pdf file (21KB) Presentations: Sharlene Weatherwax .pdf

  12. Biological Conversion of Sugars To Hydrocarbons | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    To Hydrocarbons Biological Conversion of Sugars To Hydrocarbons PDF explaining the biological process of bioenergy PDF icon Biological Conversion of Sugars To Hydrocarbons More Documents & Publications Catalytic Upgrading Sugars To Hydrocarbons Catalytic Upgrading of Sugars to Hydrocarbons Technology Pathway Biological Conversion of Sugars to Hydrocarbons Technology Pathway

  13. 2013 Biological Hydrogen Production Workshop Summary Report | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Biological Hydrogen Production Workshop Summary Report 2013 Biological Hydrogen Production Workshop Summary Report November 2013 summary report for the 2013 Biological Hydrogen Production Workshop. PDF icon bio_h2_workshop_final_report.pdf More Documents & Publications The Hydrogen Program at NREL: A Brief Overview Hydrogenases and Barriers for Biotechnological Hydrogen Production Technologies Renewable Hydrogen Production from Biological Systems

  14. EERE Success Story—California: Breakthrough in Algae Biology

    Broader source: Energy.gov [DOE]

    Breakthrough in algae biology will have a significant impact in the economics of algal biofuel production.

  15. Physics Meets Biology (LBNL Summer Lecture Series)

    ScienceCinema (OSTI)

    Chu, Steve [Director, LBNL

    2011-04-28

    Summer Lecture Series 2006: If scientists could take advantage of the awesomely complex and beautiful functioning of biologys natural molecular machines, their potential for application in many disciplines would be incalculable. Nobel Laureate and Director of the Lawrence Berkeley National Laboratory Steve Chu explores Possible solutions to global warming and its consequences.

  16. Composites comprising biologically-synthesized nanomaterials

    DOE Patents [OSTI]

    Curran, Seamus; Dias, Sampath; Blau, Werner; Wang, Jun; Oremland, Ronald S; Baesman, Shaun

    2013-04-30

    The present disclosure describes composite materials containing a polymer material and a nanoscale material dispersed in the polymer material. The nanoscale materials may be biologically synthesized, such as tellurium nanorods synthesized by Bacillus selenitireducens. Composite materials of the present disclosure may have optical limiting properties and find use in optical limiting devices.

  17. Radiological/biological/aerosol removal system

    DOE Patents [OSTI]

    Haslam, Jeffery J

    2015-03-17

    An air filter replacement system for existing buildings, vehicles, arenas, and other enclosed airspaces includes a replacement air filter for replacing a standard air filter. The replacement air filter has dimensions and air flow specifications that allow it to replace the standard air filter. The replacement air filter includes a filter material that removes radiological or biological or aerosol particles.

  18. Apparatus for automated testing of biological specimens

    DOE Patents [OSTI]

    Layne, Scott P.; Beugelsdijk, Tony J.

    1999-01-01

    An apparatus for performing automated testing of infections biological specimens is disclosed. The apparatus comprise a process controller for translating user commands into test instrument suite commands, and a test instrument suite comprising a means to treat the specimen to manifest an observable result, and a detector for measuring the observable result to generate specimen test results.

  19. Modular microfluidic system for biological sample preparation

    DOE Patents [OSTI]

    Rose, Klint A.; Mariella, Jr., Raymond P.; Bailey, Christopher G.; Ness, Kevin Dean

    2015-09-29

    A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.

  20. Biological warfare in the littorals. Final report

    SciTech Connect (OSTI)

    Larsen, R.W.

    1997-05-01

    Biological warfare (BW) has emerged as a significant threat to military operations and is particularly challenging at the operational level of warfare in a littoral environment. There are compelling reasons why an operational commander should be concerned about BW: global proliferation of biotechnology and biological weapons capabilities; suitability of BW for disrupting force projection across the littorals; and the vulnerability of American, allied and coalition forces to BW. The threat of facing an adversary capable and willing to use biological weapons will influence the commander`s application of the operational art across the six operational functions. Degradation of operational tempo, effects of psychological responses among the force, and stress on the organizational structure may challenge the command and control process. Operational intelligence will demand robust integration of technical analysis, intentions and warnings, meteorological information, and medical intelligence. The maneuver and movement processes will be taxed to function effectively when ports and airfields offer such lucrative BW targets. Biological weapons may dictate the location of operational fires assets as well as the make-up of the target lists. Operational logistics assumes great importance in the medical functions, decontamination processes, and troop replacement and unit reconstitution. Operational protection encompasses nearly every aspect of BW defense and will demand a balance between what is necessary and what is possible to protect. As daunting as the challenges appear, the operational-level commander has at his disposal many tools necessary to prepare for biological warfare in the littorals. Ultimately, the commander must convince his force, his allies, and his enemies that the command can fight effectively in a BW environment, on land and sea.

  1. January 2013 Most Viewed Documents for Biology And Medicine | OSTI, US Dept

    Office of Scientific and Technical Information (OSTI)

    of Energy, Office of Scientific and Technical Information January 2013 Most Viewed Documents for Biology And Medicine Nevada Test Site Radiological Control Manual Radiological Control Managers' Council Nevada Test Site Effects of ionizing radiation on the boreal forest: Canada's FIG experiment, with implications for radionuclides Amiro, B.D.; Sheppard, S.C Assessment of atmospheric metallic pollution in the metropolitan region of Sao Paulo, Brazil, employing Tillandsia usneoides L. as

  2. Autonomous observations of the ocean biological carbon pump

    SciTech Connect (OSTI)

    Bishop, James K.B.

    2009-03-01

    Prediction of the substantial biologically mediated carbon flows in a rapidly changing and acidifying ocean requires model simulations informed by observations of key carbon cycle processes on the appropriate space and time scales. From 2000 to 2004, the National Oceanographic Partnership Program (NOPP) supported the development of the first low-cost fully-autonomous ocean profiling Carbon Explorers that demonstrated that year-round real-time observations of particulate organic carbon (POC) concentration and sedimentation could be achieved in the world's ocean. NOPP also initiated the development of a sensor for particulate inorganic carbon (PIC) suitable for operational deployment across all oceanographic platforms. As a result, PIC profile characterization that once required shipboard sample collection and shipboard or shore based laboratory analysis, is now possible to full ocean depth in real time using a 0.2W sensor operating at 24 Hz. NOPP developments further spawned US DOE support to develop the Carbon Flux Explorer, a free-vehicle capable of following hourly variations of particulate inorganic and organic carbon sedimentation from near surface to kilometer depths for seasons to years and capable of relaying contemporaneous observations via satellite. We have demonstrated the feasibility of real time - low cost carbon observations which are of fundamental value to carbon prediction and when further developed, will lead to a fully enhanced global carbon observatory capable of real time assessment of the ocean carbon sink, a needed constraint for assessment of carbon management policies on a global scale.

  3. 2011 Archaea: Ecology, Metabolism, & Molecular Biology

    SciTech Connect (OSTI)

    Keneth Stedman

    2011-08-05

    Archaea, one of three major evolutionary lineages of life, are a fascinating and diverse group of microbes with deep roots overlapping those of eukaryotes. The focus of the 'Archaea: Ecology Metabolism & Molecular Biology' GRC conference expands on a number of emerging topics highlighting new paradigms in archaeal metabolism, genome function and systems biology; information processing; evolution and the tree of life; the ecology and diversity of archaea and their viruses. The strength of this conference lies in its ability to couple a field with a rich history in high quality research with new scientific findings in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  4. Monitoring Biological Activity at Geothermal Power Plants

    SciTech Connect (OSTI)

    Peter Pryfogle

    2005-09-01

    The economic impact of microbial growth in geothermal power plants has been estimated to be as high as $500,000 annually for a 100 MWe plant. Many methods are available to monitor biological activity at these facilities; however, very few plants have any on-line monitoring program in place. Metal coupon, selective culturing (MPN), total organic carbon (TOC), adenosine triphosphate (ATP), respirometry, phospholipid fatty acid (PLFA), and denaturing gradient gel electrophoresis (DGGE) characterizations have been conducted using water samples collected from geothermal plants located in California and Utah. In addition, the on-line performance of a commercial electrochemical monitor, the BIoGEORGE?, has been evaluated during extended deployments at geothermal facilities. This report provides a review of these techniques, presents data on their application from laboratory and field studies, and discusses their value in characterizing and monitoring biological activities at geothermal power plants.

  5. 2009 Archaea: Ecology, Metabolism & Molecular Biology GRC

    SciTech Connect (OSTI)

    Dr. Julie Maupin- Furlow

    2009-07-26

    Archaea, one of three major evolutionary lineages of life, are a fascinating and diverse group of microbes with deep roots overlapping those of eukaryotes. The focus of the 'Archaea: Ecology Metabolism & Molecular Biology' GRC conference expands on a number of emerging topics highlighting new paradigms in archaeal metabolism, genome function and systems biology; information processing; evolution and the tree of life; the ecology and diversity of archaea and their viruses; and industrial applications. The strength of this conference lies in its ability to couple a field with a rich history in high quality research with new scientific findings in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  6. Biology and Medicine Division annual report, 1987

    SciTech Connect (OSTI)

    Not Available

    1988-04-01

    Modern biology is characterized by rapid change. The development of new tools and the results derived from their application to various biological systems require significant shifts in our concepts and the strategies that are adopted to analyze and elucidate mechanisms. In parallel with exciting new scientific developments our organizational structure and programmatic emphases have altered. These changes and developments have enabled the life sciences at LBL to be better positioned to create and respond to new opportunities. The work summarized in this annual report reflects a vital multifaceted research program that is in the vanguard of the areas represented. We are committed to justifying the confidence expressed by LBL through the new mission statement and reorganizational changes designed to give greater prominence to the life sciences.

  7. Chemical and biological warfare: Detection and warning systems. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect (OSTI)

    1995-03-01

    The bibliography contains citations concerning the detection, identification, verification, and warning systems of chemical and biological warfare agents. Citations discuss agents sampling, monitoring, and assessment. Techniques include chromotography, biosensing, chemical analysis, and DNA probes. Land pollution, soil tests, and skin protection are examined. (Contains a minimum of 244 citations and includes a subject term index and title list.)

  8. Chemical and biological warfare: Detection and warning systems. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect (OSTI)

    1996-10-01

    The bibliography contains citations concerning the detection, identification, verification, and warning systems of chemical and biological warfare agents. Citations discuss agents sampling, monitoring, and assessment. Techniques include chromotography, biosensing, chemical analysis, and DNA probes. Land pollution, soil tests, and skin protection are examined. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  9. Developing Biological Specifications for Fish Friendly Turbines

    SciTech Connect (OSTI)

    Neitzel, Duane A.

    2009-09-14

    This factsheet explains studies conducted in a highly reproducible manner to examine the biological effects to fish exposed to a shear environment in the laboratory. Strain rate was used as the index of intensity to describe the hydraulic force experienced by a fish in a shear environment. It was determined that no significant injuries occurred to any fish subjected to strain rates equal to or less than 500 cm/s/cm.

  10. Assessing the impacts of climate change on natural resource systems

    SciTech Connect (OSTI)

    Frederick, K.D.; Rosenberg, N.J. [eds.

    1994-11-30

    This volume is a collection of papers addressing the theme of potential impacts of climatic change. Papers are entitled Integrated Assessments of the Impacts of Climatic Change on Natural Resources: An Introductory Editorial; Framework for Integrated Assessments of Global Warming Impacts; Modeling Land Use and Cover as Part of Global Environmental Change; Assessing Impacts of Climatic Change on Forests: The State of Biological Modeling; Integrating Climatic Change and Forests: Economic and Ecological Assessments; Environmental Change in Grasslands: Assessment using Models; Assessing the Socio-economic Impacts of Climatic Change on Grazinglands; Modeling the Effects of Climatic Change on Water Resources- A Review; Assessing the Socioeconomic Consequences of Climate Change on Water Resources; and Conclusions, Remaining Issues, and Next Steps.

  11. KPFM and PFM of Biological Systems

    SciTech Connect (OSTI)

    Rodriguez, Brian [University College, Dublin; Kalinin, Sergei V [ORNL

    2011-01-01

    Surface potentials and electrostatic interactions in biological systems are a key element of cellular regulation and interaction. Examples include cardiac and muscular activity, voltage-gated ion channels, protein folding and assembly, and electroactive cells and electrotransduction. The coupling between electrical, mechanical, and chemical signals and responses in cellular systems necessitates the development of tools capable of measuring the distribution of charged species, surface potentials, and mechanical responses to applied electrical stimuli and vice versa, ultimately under physiological conditions. In this chapter, applications of voltage-modulated atomic force microscopy (AFM) methods including Kelvin probe force microscopy (KPFM) and piezoresponse force microscopy (PFM) to biological systems are discussed. KPFM is a force-sensitive non-contact or intermittent-contact mode AFM technique that allows electrostatic interactions and surface potentials to be addressed. Beyond long-range electrostatic interactions, the application of bias can lead to a mechanical response, e.g., due to linear piezoelectric coupling in polar biopolymers or via more complex electrotransduction and redox pathways in other biosystems. The use and development of PFM, based on direct electromechanical detection, to biological systems will also be addressed. The similarities and limitations of measuring surface potentials and electromechanical coupling in solution will be outlined.

  12. Sandia Energy - Resource Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Resource Assessment Home Stationary Power Energy Conversion Efficiency Water Power Resource Assessment Resource AssessmentAshley Otero2016-01-05T19:06:04+00:00 Characterizing wave...

  13. ORISE: Hazard Assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    internal and external radiation dose assessments. Our capabililities include: Linkage of exposure data to site rosters Assessment of retrospective exposures Preparation of...

  14. Northwest Energy Market Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Northwest Energy Market Assessment Pages Northwest-Energy-Market-Assessment Sign In About | Careers | Contact | Investors | bpa.gov Search News & Us Expand News & Us Projects &...

  15. Human Reliability Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reliability Assessment - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us ... Twitter Google + Vimeo GovDelivery SlideShare Human Reliability Assessment HomeStationary ...

  16. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Biological Imaging by Soft X-Ray Diffraction Microscopy Print Wednesday, 30 November 2005 00:00 Electron and x-ray...

  17. BioLogical Capital BLC | Open Energy Information

    Open Energy Info (EERE)

    BioLogical Capital BLC Jump to: navigation, search Name: BioLogical Capital (BLC) Place: Denver, Colorado Zip: 80202 Product: Denver Colorado-based group focusing on generating...

  18. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure The Biological Implications of the PP2A Crystal Structure Print Wednesday, 30 January 2008 00:00 Phosphatases, enzymes...

  19. Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 PDF icon b2blowres63006.pdf More Documents & Publications Breaking the Biological Barriers to Cellulosic Ethanol, June 2006 Review of Recent Pilot Scale Cellulosic Ethanol Demonstration Biochemical Conversion: Using Hydrolysis, Fermentation, and Catalysis to Make Fuels and

  20. Biological Conversion of Sugars to Hydrocarbons Technology Pathway

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... to leverage experience in biochemical processing, specifically cellulose and ... in downstream biological conversion and improving overall process integration. ...

  1. Survey of Biomass Resource Assessments and Assessment Capabilities...

    Open Energy Info (EERE)

    Biomass Resource Assessments and Assessment Capabilities in APEC Economies Jump to: navigation, search Logo: Survey of Biomass Resource Assessments and Assessment Capabilities in...

  2. AN INTEGRATED BIOLOGICAL CONTROL SYSTEM AT HANFORD

    SciTech Connect (OSTI)

    JOHNSON AR; CAUDILL JG; GIDDINGS RF; RODRIGUEZ JM; ROOS RC; WILDE JW

    2010-02-11

    In 1999 an integrated biological control system was instituted at the U.S. Department of Energy's Hanford Site. Successes and changes to the program needed to be communicated to a large and diverse mix of organizations and individuals. Efforts at communication are directed toward the following: Hanford Contractors (Liquid or Tank Waste, Solid Waste, Environmental Restoration, Science and Technology, Site Infrastructure), General Hanford Employees, and Hanford Advisory Board (Native American Tribes, Environmental Groups, Local Citizens, Washington State and Oregon State regulatory agencies). Communication was done through direct interface meetings, individual communication, where appropriate, and broadly sharing program reports. The objectives of the communication efforts was to have the program well coordinated with Hanford contractors, and to have the program understood well enough that all stakeholders would have confidence in the work performed by the program to reduce or elimated spread of radioactive contamination by biotic vectors. Communication of successes and changes to an integrated biological control system instituted in 1999 at the Department of Energy's Hanford Site have required regular interfaces with not only a diverse group of Hanford contractors (i.e., those responsible for liquid or tank waste, solid wastes, environmental restoration, science and technology, and site infrastructure), and general Hanford employees, but also with a consortium of designated stake holders organized as the Hanford Advisory Board (i.e., Native American tribes, various environmental groups, local citizens, Washington state and Oregon regulatory agencies, etc.). Direct interface meetings, individual communication where appropriate, and transparency of the biological control program were the methods and outcome of this effort.

  3. Sandia Energy - Solar Resource Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Solar Resource Assessment Home Stationary Power Energy Conversion Efficiency Solar Energy Photovoltaics Solar Resource Assessment Solar Resource AssessmentTara...

  4. Portsmouth Needs Assessment

    Broader source: Energy.gov [DOE]

    Needs Assessment for former Oak Ridge K-25, Paducah, and Portsmouth Gaseous Diffusion Plant production workers.

  5. LABORATORY OF NUCLEAR MEDICINE AND RADIATION BIOLOGY

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MEDICINE AND RADIATION BIOLOGY 900 VETERAN AVENUE UNIVERSITY OF CALIFORNIA, LOS ANGELES, CALIFORNIA 90024 AND DEPARTMENT OF RADIOLOGICAL SCIENCES UCLA SCHOOL OF MEDICINE, LOS ANGELES, CALIFORNIA 90024 This manuscript is a contribution to the monograph edited by Daniel S. Berman and Dean Mason, entitled "Clinical Nuclear Cardiology". These studies were supported by Contract #DE-AM03-76-SF00012 between the U.S. Department of Energy and the University of California Prepared for the U.S.

  6. LANSCE | Lujan Center | Biology Preparation Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology Preparation Laboratory The Lujan Center Biolab offers a variety of capabilities. 1) Biodeuteration Lab (BDL) We run a protein expression lab for perdeuteration of user proteins. We offer full perdeuteration (~99%) using our algal-based media for bacterial growth. We also have M9 minimal media made in D2O for expression of up to ~85% perdeuteration. Users can use our lab in person or mail-in a plasmid for us to express for them. We also have standard protein expression equipment:

  7. Historical Information H.2 Biological Studies

    Office of Legacy Management (LM)

    _-_ . - H.2 Biological Studies (0 \ j ; : : j Book . l Ad Hoc Rulison Review Panel Comments Regarding Re-Entry , and Testing Operations, December 22, 1969 This page intentionally left blank December 22, 1969 M r . Robert E. Miller, Manager Nevada Operations Office U. S. Atomic Energy Commission Post Office Box 14100 Las Vegas, Nevada 89114 Dear M r . Miller: F4cmbers of t h e A d Hoc Rulison Review Panel reconvened on December 22, 1969, t o hear and discuss comments r e s u l t i n g from our

  8. Synchronous Behavior of Two Coupled Biological Neurons

    SciTech Connect (OSTI)

    Elson, R.C.; Selverston, A.I.; Elson, R.C.; Selverston, A.I.; Huerta, R.; Rulkov, N.F.; Rabinovich, M.I.; Abarbanel, H.D.; Selverston, A.I.; Huerta, R.; Abarbanel, H.D.

    1998-12-01

    We report experimental studies of synchronization phenomena in a pair of biological neurons that interact through naturally occurring, electrical coupling. When these neurons generate irregular bursts of spikes, the natural coupling synchronizes slow oscillations of membrane potential, but not the fast spikes. By adding artificial electrical coupling we studied transitions between synchrony and asynchrony in both slow oscillations and fast spikes. We discuss the dynamics of bursting and synchronization in living neurons with distributed functional morphology. {copyright} {ital 1998} {ital The American Physical Society}

  9. Third international congress of plant molecular biology: Molecular biology of plant growth and development

    SciTech Connect (OSTI)

    Hallick, R.B.

    1995-02-01

    The Congress was held October 6-11, 1991 in Tucson with approximately 3000 scientists attending and over 300 oral presentations and 1800 posters. Plant molecular biology is one of the most rapidly developing areas of the biological sciences. Recent advances in the ability to isolate genes, to study their expression, and to create transgenic plants have had a major impact on our understanding of the many fundamental plant processes. In addition, new approaches have been created to improve plants for agricultural purposes. This is a book of presentation and posters from the conference.

  10. ORISE: Hazard Assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hazard Assessments The Oak Ridge Institute for Science and Education (ORISE) analyzes accumulated data to identify potential workplace hazards to which individuals or groups of workers may be exposed. ORISE assesses both chemical and radiation exposures, and conducts both internal and external radiation dose assessments. Our capabililities include: Linkage of exposure data to site rosters Assessment of retrospective exposures Preparation of assessment protocols Design and testing of dose

  11. Biological and Environmental Research Network Requirements

    SciTech Connect (OSTI)

    Balaji, V.; Boden, Tom; Cowley, Dave; Dart, Eli; Dattoria, Vince; Desai, Narayan; Egan, Rob; Foster, Ian; Goldstone, Robin; Gregurick, Susan; Houghton, John; Izaurralde, Cesar; Johnston, Bill; Joseph, Renu; Kleese-van Dam, Kerstin; Lipton, Mary; Monga, Inder; Pritchard, Matt; Rotman, Lauren; Strand, Gary; Stuart, Cory; Tatusova, Tatiana; Tierney, Brian; Thomas, Brian; Williams, Dean N.; Zurawski, Jason

    2013-09-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet be a highly successful enabler of scientific discovery for over 25 years. In November 2012, ESnet and the Office of Biological and Environmental Research (BER) of the DOE SC organized a review to characterize the networking requirements of the programs funded by the BER program office. Several key findings resulted from the review. Among them: 1) The scale of data sets available to science collaborations continues to increase exponentially. This has broad impact, both on the network and on the computational and storage systems connected to the network. 2) Many science collaborations require assistance to cope with the systems and network engineering challenges inherent in managing the rapid growth in data scale. 3) Several science domains operate distributed facilities that rely on high-performance networking for success. Key examples illustrated in this report include the Earth System Grid Federation (ESGF) and the Systems Biology Knowledgebase (KBase). This report expands on these points, and addresses others as well. The report contains a findings section as well as the text of the case studies discussed at the review.

  12. 2010 Plant Molecular Biology Gordon Research Conference

    SciTech Connect (OSTI)

    Michael Sussman

    2010-07-23

    The Plant Molecular Biology Conference has traditionally covered a breadth of exciting topics and the 2010 conference will continue in that tradition. Emerging concerns about food security have inspired a program with three main themes: (1) genomics, natural variation and breeding to understand adaptation and crop improvement, (2) hormonal cross talk, and (3) plant/microbe interactions. There are also sessions on epigenetics and proteomics/metabolomics. Thus this conference will bring together a range of disciplines, will foster the exchange of ideas and enable participants to learn of the latest developments and ideas in diverse areas of plant biology. The conference provides an excellent opportunity for individuals to discuss their research because additional speakers in each session will be selected from submitted abstracts. There will also be a poster session each day for a two-hour period prior to dinner. In particular, this conference plays a key role in enabling students and postdocs (the next generation of research leaders) to mingle with pioneers in multiple areas of plant science.

  13. Acceptance Criteria Framework for Autonomous Biological Detectors

    SciTech Connect (OSTI)

    Dzenitis, J M

    2006-12-12

    The purpose of this study was to examine a set of user acceptance criteria for autonomous biological detection systems for application in high-traffic, public facilities. The test case for the acceptance criteria was the Autonomous Pathogen Detection System (APDS) operating in high-traffic facilities in New York City (NYC). However, the acceptance criteria were designed to be generally applicable to other biological detection systems in other locations. For such detection systems, ''users'' will include local authorities (e.g., facility operators, public health officials, and law enforcement personnel) and national authorities [including personnel from the Department of Homeland Security (DHS), the BioWatch Program, the Centers for Disease Control and Prevention (CDC), and the Federal Bureau of Investigation (FBI)]. The panel members brought expertise from a broad range of backgrounds to complete this picture. The goals of this document are: (1) To serve as informal guidance for users in considering the benefits and costs of these systems. (2) To serve as informal guidance for developers in understanding the needs of users. In follow-up work, this framework will be used to systematically document the APDS for appropriateness and readiness for use in NYC.

  14. Effects of simulated rare earth recycling wastewaters on biological nitrification

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Fujita, Yoshiko; Barnes, Joni; Eslamimanesh, Ali; Lencka, Malgorzata M.; Anderko, Andrzej; Riman, Richard E.; Navrotsky, Alexandra

    2015-07-16

    Current efforts to increase domestic availability of rare-earth element (REE) supplies by recycling and expanded ore processing efforts will result in increased generation of associated wastewaters. In some cases disposal to a sewage treatment plant may be favored but plant performance must be maintained. To assess the potential effects of such wastewaters on biological wastewater treatment, model nitrifying organisms Nitrosomonas europaea and Nitrobacter winogradskyi were exposed to simulated wastewaters containing varying levels of yttrium or europium (10, 50 and 100 ppm), and the REE extractant tributyl phosphate (TBP, at 0.1 g/L). Y and Eu additions above 10 ppm inhibited N.more » europaea activity, even when initially virtually all of the REE was insoluble. The provision of TBP together with Eu increased inhibition of nitrite production by the N. europaea, although TBP alone did not substantially alter nitrifying activity N. winogradskyi was more sensitive to the stimulated wastewaters, with even 10 ppm Eu or Y inducing significant inhibition, and a complete shutdown of nitrifying activity occurred in the presence of the TBP. To analyze the availability of REEs in aqueous solutions, REE solubility has been calculated using the previously developed MSE (Mixed-Solvent Electrolyte) thermodynamic model. The model calculations reveal a strong pH dependence of solubility, which is typically controlled by the precipitation of REE hydroxides but may also be influenced by the formation of a phosphate phase.« less

  15. Effects of simulated rare earth recycling wastewaters on biological nitrification

    SciTech Connect (OSTI)

    Fujita, Yoshiko; Barnes, Joni; Eslamimanesh, Ali; Lencka, Malgorzata M.; Anderko, Andrzej; Riman, Richard E.; Navrotsky, Alexandra

    2015-07-16

    Current efforts to increase domestic availability of rare-earth element (REE) supplies by recycling and expanded ore processing efforts will result in increased generation of associated wastewaters. In some cases disposal to a sewage treatment plant may be favored but plant performance must be maintained. To assess the potential effects of such wastewaters on biological wastewater treatment, model nitrifying organisms Nitrosomonas europaea and Nitrobacter winogradskyi were exposed to simulated wastewaters containing varying levels of yttrium or europium (10, 50 and 100 ppm), and the REE extractant tributyl phosphate (TBP, at 0.1 g/L). Y and Eu additions above 10 ppm inhibited N. europaea activity, even when initially virtually all of the REE was insoluble. The provision of TBP together with Eu increased inhibition of nitrite production by the N. europaea, although TBP alone did not substantially alter nitrifying activity N. winogradskyi was more sensitive to the stimulated wastewaters, with even 10 ppm Eu or Y inducing significant inhibition, and a complete shutdown of nitrifying activity occurred in the presence of the TBP. To analyze the availability of REEs in aqueous solutions, REE solubility has been calculated using the previously developed MSE (Mixed-Solvent Electrolyte) thermodynamic model. The model calculations reveal a strong pH dependence of solubility, which is typically controlled by the precipitation of REE hydroxides but may also be influenced by the formation of a phosphate phase.

  16. Department of Defense Nuclear/Biological/Chemical (NBC) warfare defense, annual report to Congress. Final report FY96

    SciTech Connect (OSTI)

    1996-04-01

    The National Defense Authorization Act for Fiscal Year 1994, Public Law No. 103-160, Section 1703, mandates the consolidation of all Department of Defense chemical and biological defense programs. As part of this consolidation, the Secretary of Defense is directed to submit an assessment and a description of plans to improve readiness to survive, fight and win in a chemically or biologically contaminated environment. This report contains modernizations plan summaries which highlight the Department`s approach to improve current NBC defense equipment and resolve current shortcomings in the program.

  17. Distributed road assessment system

    DOE Patents [OSTI]

    Beer, N. Reginald; Paglieroni, David W

    2014-03-25

    A system that detects damage on or below the surface of a paved structure or pavement is provided. A distributed road assessment system includes road assessment pods and a road assessment server. Each road assessment pod includes a ground-penetrating radar antenna array and a detection system that detects road damage from the return signals as the vehicle on which the pod is mounted travels down a road. Each road assessment pod transmits to the road assessment server occurrence information describing each occurrence of road damage that is newly detected on a current scan of a road. The road assessment server maintains a road damage database of occurrence information describing the previously detected occurrences of road damage. After the road assessment server receives occurrence information for newly detected occurrences of road damage for a portion of a road, the road assessment server determines which newly detected occurrences correspond to which previously detected occurrences of road damage.

  18. Conservation assessment for the Siskiyou Mountains salamander and Scott Bar salamander in northern California.

    SciTech Connect (OSTI)

    Vinikour, W. S.; LaGory, K. E.; Adduci, J. J.; Environmental Science Division

    2006-10-20

    The purpose of this conservation assessment is to summarize existing knowledge regarding the biology and ecology of the Siskiyou Mountains salamander and Scott Bar salamander, identify threats to the two species, and identify conservation considerations to aid federal management for persistence of the species. The conservation assessment will serve as the basis for a conservation strategy for the species.

  19. ANAEROBIC BIOLOGICAL TREATMENT OF PRODUCED WATER

    SciTech Connect (OSTI)

    John R. Gallagher

    2001-07-31

    During the production of oil and gas, large amounts of water are brought to the surface and must be disposed of in an environmentally sensitive manner. This is an especially difficult problem in offshore production facilities where space is a major constraint. The chief regulatory criterion for produced water is oil and grease. Most facilities have little trouble meeting this criterion using conventional oil-water separation technologies. However, some operations have significant amounts of naphthenic acids in the water that behave as oil and grease but are not well removed by conventional technologies. Aerobic biological treatment of naphthenic acids in simulated-produced water has been demonstrated by others; however, the system was easily overloaded by the large amounts of low-molecular-weight organic acids often found in produced waters. The objective of this research was to determine the ability of an anaerobic biological system to treat these organic acids in a simulated produced water and to examine the potential for biodegradation of the naphthenic acids in the anaerobic environment. A small fixed-film anaerobic biological reactor was constructed and adapted to treat a simulated produced water. The bioreactor was tubular, with a low-density porous glass packing material. The inocula to the reactor was sediment from a produced-water holding pond from a municipal anaerobic digester and two salt-loving methanogenic bacteria. During start-up, the feed to the reactor contained glucose as well as typical produced-water components. When glucose was used, rapid gas production was observed. However, when glucose was eliminated and the major organic component was acetate, little gas was generated. Methane production from acetate may have been inhibited by the high salt concentrations, by sulfide, or because of the lack, despite seeding, of microbes capable of converting acetate to methane. Toluene, a minor component of the produced water (0.1 g/L) was removed in the reactor. Batch tests were conducted to examine naphthenic acid biodegradability under several conditions. The conditions used were seed from the anaerobic reactor, wetland sediments under aerobic and anaerobic conditions, and a sterile control. The naphthenic acid was from a commercial source isolated from Gulf Coast petroleum as was dosed at 2 mg/mL. The incubations were for 30 days at 30 C. The results showed that the naphthenic acids were not biodegraded under anaerobic conditions, but were degraded under aerobic conditions. Despite poor performance of the anaerobic reactor, it remains likely that anaerobic treatment of acetate, toluene, and, potentially, other produced-water components is feasible.

  20. Biology and Medicine Division annual report, 1985

    SciTech Connect (OSTI)

    Not Available

    1986-04-01

    This book briefly describes the activities of the Biology and Medicine Division of the Lawrence Berkeley Laboratory. During the past year the Donner Pavilion program on the treatment of arteriovenous malformations in the brain has chalked up very significant successes. The disease control rate has been high and objective measures of success using cerebral angiography have been established. The new high resolution positron emitting tomographic imager has been demonstrated to operate successfully. In the Radiation Biophysics program, the availability of higher mass ions up to uranium has allowed us cell and tissue studies in a radiation domain that is entirely new. Using uranium beams, investigators have already made new and exciting findings that are described in the body of the report.

  1. 2010 Diffraction Methods in Structural Biology

    SciTech Connect (OSTI)

    Dr. Ana Gonzalez

    2011-03-10

    Advances in basic methodologies have played a major role in the dramatic progress in macromolecular crystallography over the past decade, both in terms of overall productivity and in the increasing complexity of the systems being successfully tackled. The 2010 Gordon Research Conference on Diffraction Methods in Structural Biology will, as in the past, focus on the most recent developments in methodology, covering all aspects of the process from crystallization to model building and refinement, complemented by examples of structural highlights and complementary methods. Extensive discussion will be encouraged and it is hoped that all attendees will participate by giving oral or poster presentations, the latter using the excellent poster display area available at Bates College. The relatively small size and informal atmosphere of the meeting provides an excellent opportunity for all participants, especially younger scientists, to meet and exchange ideas with leading methods developers.

  2. Overview of selected molecular biological databases

    SciTech Connect (OSTI)

    Rayl, K.D.; Gaasterland, T.

    1994-11-01

    This paper presents an overview of the purpose, content, and design of a subset of the currently available biological databases, with an emphasis on protein databases. Databases included in this summary are 3D-ALI, Berlin RNA databank, Blocks, DSSP, EMBL Nucleotide Database, EMP, ENZYME, FSSP, GDB, GenBank, HSSP, LiMB, PDB, PIR, PKCDD, ProSite, and SWISS-PROT. The goal is to provide a starting point for researchers who wish to take advantage of the myriad available databases. Rather than providing a complete explanation of each database, we present its content and form by explaining the details of typical entries. Pointers to more complete ``user guides`` are included, along with general information on where to search for a new database.

  3. Quantifying evolvability in small biological networks

    SciTech Connect (OSTI)

    Nemenman, Ilya; Mugler, Andrew; Ziv, Etay; Wiggins, Chris H

    2008-01-01

    The authors introduce a quantitative measure of the capacity of a small biological network to evolve. The measure is applied to a stochastic description of the experimental setup of Guet et al. (Science 2002, 296, pp. 1466), treating chemical inducers as functional inputs to biochemical networks and the expression of a reporter gene as the functional output. The authors take an information-theoretic approach, allowing the system to set parameters that optimise signal processing ability, thus enumerating each network's highest-fidelity functions. All networks studied are highly evolvable by the measure, meaning that change in function has little dependence on change in parameters. Moreover, each network's functions are connected by paths in the parameter space along which information is not significantly lowered, meaning a network may continuously change its functionality without completely losing it along the way. This property further underscores the evolvability of the networks.

  4. Recovery from chemical, biological, and radiological incidents :

    SciTech Connect (OSTI)

    Franco, David Oliver; Yang, Lynn I.; Hammer, Ann E.

    2012-06-01

    To restore regional lifeline services and economic activity as quickly as possible after a chemical, biological or radiological incident, emergency planners and managers will need to prioritize critical infrastructure across many sectors for restoration. In parallel, state and local governments will need to identify and implement measures to promote reoccupation and economy recovery in the region. This document provides guidance on predisaster planning for two of the National Disaster Recovery Framework Recovery Support Functions: Infrastructure Systems and Economic Recovery. It identifies key considerations for infrastructure restoration, outlines a process for prioritizing critical infrastructure for restoration, and identifies critical considerations for promoting regional economic recovery following a widearea disaster. Its goal is to equip members of the emergency preparedness community to systematically prioritize critical infrastructure for restoration, and to develop effective economic recovery plans in preparation for a widearea CBR disaster.

  5. Solar Resource Assessment

    SciTech Connect (OSTI)

    Renne, D.; George, R.; Wilcox, S.; Stoffel, T.; Myers, D.; Heimiller, D.

    2008-02-01

    This report covers the solar resource assessment aspects of the Renewable Systems Interconnection study. The status of solar resource assessment in the United States is described, and summaries of the availability of modeled data sets are provided.

  6. Caraustar Industries Energy Assessment

    SciTech Connect (OSTI)

    2010-06-25

    This plant-wide assessment case study is about commissioned energy assessments by the U.S. Department of Energy Industrial Technologies Program at two of Caraustar's recycled paperboard mills.

  7. Home Energy Assessments

    Broader source: Energy.gov [DOE]

    A home energy assessment, also known as a home energy audit, is the first step to assess how much energy your home consumes and to evaluate what measures you can take to make your home more energy...

  8. Ecological Risk Assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Community, Environment » Environmental Stewardship » Environmental Protection » Ecological Risk Assessments Ecological Risk Assessments Ecological risk assessment is the appraisal of potential adverse effects of exposure to contaminants on plants and animals. Contact Environmental Communication & Public Involvement P.O. Box 1663 MS M996 Los Alamos, NM 87545 (505) 667-0216 Email The ECORISK Database is a screening tool that helps scientists evaluate impacts on LANL's ecology. Assessing our

  9. Management Assessment and Independent Assessment Guide

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2001-05-31

    The revision to this Guide reflects current assessment practices, international standards, and changes in the Department of Energy expectations. Cancels DOE G 414.1-1. Canceled by DOE G 414.1-1B.

  10. CRAD, Self-Assessment Program Assessment Plan

    Broader source: Energy.gov [DOE]

    Management should ensure that effective management and independent self-assessments are being conducted periodically by technically qualified personnel. [10 CFR 830.122, subpart A & DOE O 414.1A, Quality Assurance

  11. Assessing the assessments: Pharmaceuticals in the environment

    SciTech Connect (OSTI)

    Enick, O.V. Moore, M.M.

    2007-11-15

    The relatively new issue of pharmaceutical contamination of the environment offers the opportunity to explore the application of values to the construction, communication and management of risk. The still-developing regulatory policies regarding environmental contamination with pharmaceuticals provide fertile ground for the introduction of values into the definition and management of risk. In this report, we summarize the current knowledge regarding pharmaceutical contamination of the environment and discuss specific attributes of pharmaceuticals that require special consideration. We then present an analysis showing that if values are incorporated into assessing, characterizing and managing risk, the results of risk assessments will more accurately reflect the needs of various stakeholders. Originating from an acknowledgement of the inherent uncertainty and value-laden nature of risk assessment, the precautionary principle (and later, the multi-criteria, integrated risk assessment), provides a direction for further research and policy development.

  12. Risk Assessment & Management Information

    Broader source: Energy.gov [DOE]

    NRC - A Proposed Risk Management Regulatory Framework, April 2012 Risk Assessment Technical Experts Working Group (RWG) web page DOE Standard on Development and Use of Probabilistic Risk Assessment in DOE Nuclear Safety Applications (draft), December 2010 Consortium for Risk Evaluation with Stakeholder Participation Workshop on Risk Assessment and Safety Decision Making Under Uncertainty

  13. Modular microfluidic system for biological sample preparation (Patent) |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Modular microfluidic system for biological sample preparation Citation Details In-Document Search Title: Modular microfluidic system for biological sample preparation A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis

  14. Biological Conversion of Sugars to Hydrocarbons Technology Pathway

    Office of Scientific and Technical Information (OSTI)

    (Technical Report) | SciTech Connect Biological Conversion of Sugars to Hydrocarbons Technology Pathway Citation Details In-Document Search Title: Biological Conversion of Sugars to Hydrocarbons Technology Pathway This technology pathway case investigates the biological conversion of biomass-derived sugars to hydrocarbon biofuels, utilizing data from recent literature references and information consistent with recent pilot-scale demonstrations at NREL. Technical barriers and key research

  15. Deadline Extended for RFI on Biological Hydrogen Production | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Deadline Extended for RFI on Biological Hydrogen Production Deadline Extended for RFI on Biological Hydrogen Production February 26, 2014 - 12:00am Addthis DOE has extended the submission deadline for this Request for Information. Responses must be submitted by 5:00 p.m. Eastern Time on March 14, 2014. The U.S. Department of Energy's (DOE's) Fuel Cell Technologies Office has issued a request for information (RFI) seeking feedback from interested stakeholders regarding biological

  16. Lessons about vulnerability assessments.

    SciTech Connect (OSTI)

    Johnston, R. G.

    2004-01-01

    The Vulnerability Assessment Team (VAT) at Los Alamos National Laboratory believes that physical security can only be optimized through the use of effective vulnerability assessments. As a result of conducting vulnerability assessments on hundreds of different security devices and systems in the last few years, we have identified some of the attributes of effective assessments. These, along with our recommendations and observations about vulnerability assessments, are summarized in this paper. While our work has primarily involved physical security (in contrast to, for example, computer, network, or information security), our experiences may have applicability to other types of security as well.

  17. Home Energy Assessments

    ScienceCinema (OSTI)

    Dispenza, Jason

    2013-05-29

    A home energy assessment, also known as a home energy audit, is the first step to assess how much energy your home consumes and to evaluate what measures you can take to make your home more energy efficient. An assessment will show you problems that may, when corrected, save you significant amounts of money over time. This video shows some of the ways that a contractor may test your home during an assessment, and helps you understand how an assessment can help you move toward energy savings. Find out more at: http://www.energysavers.gov/your_home/energy_audits/index.cfm/mytopic=11160

  18. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production

    Broader source: Energy.gov [DOE]

    Report documenting the biological and engineering characteristics of five algal and bacterial hydrogen production systems selected by DOE and NREL for evaluation.

  19. Division of Chemical & Biological Sciences | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Chemical & Biological Sciences Previous Pause Next Welcome Research teams in this Division ... We work to develop new catalysts that enable more efficient chemical reactions, discover ...

  20. Functionalized apertures for the detection of chemical and biological materials

    DOE Patents [OSTI]

    Letant, Sonia E.; van Buuren, Anthony W.; Terminello, Louis J.; Thelen, Michael P.; Hope-Weeks, Louisa J.; Hart, Bradley R.

    2010-12-14

    Disclosed are nanometer to micron scale functionalized apertures constructed on a substrate made of glass, carbon, semiconductors or polymeric materials that allow for the real time detection of biological materials or chemical moieties. Many apertures can exist on one substrate allowing for the simultaneous detection of numerous chemical and biological molecules. One embodiment features a macrocyclic ring attached to cross-linkers, wherein the macrocyclic ring has a biological or chemical probe extending through the aperture. Another embodiment achieves functionalization by attaching chemical or biological anchors directly to the walls of the apertures via cross-linkers.

  1. Molecular biology of signal transduction in plants. Abstracts

    SciTech Connect (OSTI)

    Not Available

    1991-12-31

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  2. Biological and Environmental Research Advisory CommitteeOctober...

    Office of Science (SC) Website

    Sharlene Weatherwax .pdf file (440KB) - Office of Biological and Environmental Research Update Gary Geernaert .pdf file (2.1MB) - Climate and Environmental Sciences Division Update ...

  3. Browse by Discipline -- E-print Network Subject Pathways: Biology...

    Office of Scientific and Technical Information (OSTI)

    Biological, and Environmental Engineering, Oregon State University Williams, John M. (John M. Williams) - Petroleum Engineering program, Petroleum Institute (Abu Dhabi) Go ...

  4. DOE Issues Request for Information on Biological Hydrogen Production...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    a request for information (RFI) seeking feedback from interested stakeholders regarding ... Feedback is specifically requested on the workshop report for the Biological Hydrogen ...

  5. Linqu Qinchi Biological Co Ltd | Open Energy Information

    Open Energy Info (EERE)

    City, Shandong Province, China Zip: 262600 Product: Shandong-based developer of a biogas plant that registered as a CDM project. References: Linqu Qinchi Biological Co.,...

  6. Synthetic biology for microbial production of lipid-based biofuels...

    Office of Scientific and Technical Information (OSTI)

    Synthetic biology for microbial production of lipid-based biofuels Citation Details In-Document Search This content will become publicly available on October 22, 2017 Title: ...

  7. Biological Conversion of Sugars to Hydrocarbons Technology Pathway...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    This technology pathway case investigates the biological conversion of biomass-derived sugars to hydrocarbon biofuels, utilizing data from recent literature references and ...

  8. Synthesis, crystal, and biological activity of a novel carbene...

    Office of Scientific and Technical Information (OSTI)

    carbene silver(I) complex with imidazole derivative Citation Details In-Document Search Title: Synthesis, crystal, and biological activity of a novel carbene silver(I) complex ...

  9. Importance of systems biology in engineering microbes for biofuel...

    Office of Scientific and Technical Information (OSTI)

    Importance of systems biology in engineering microbes for biofuel production Citation ... resources has catalyzed numerous research endeavors that focus on developing ...

  10. Systems biology analysis of Zymomonas mobilis ZM4 ethanol stress...

    Office of Scientific and Technical Information (OSTI)

    However, the molecular mechanisms of ethanol stress response have not been elucidated fully. In this study, ethanol stress responses were investigated using systems biology tools. ...

  11. DOE Issues Request for Information on Biological Hydrogen Production

    Broader source: Energy.gov [DOE]

    The Fuel Cell Technologies Office has issued a request for information seeking feedback from interested stakeholders regarding biological hydrogen production research and development.

  12. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production

    SciTech Connect (OSTI)

    James, B. D.; Baum, G. N.; Perez, J.; Baum, K. N.

    2009-09-01

    Report documenting the biological and engineering characteristics of five algal and bacterial hydrogen production systems selected by DOE and NREL for evaluation.

  13. Genomics and Systems Biology of Tuberculosis (2009 JGI User Meeting)

    ScienceCinema (OSTI)

    Galagan, James

    2011-04-25

    James Galagan from the Broad Institute spoke about the "Genomics and Systems Biology of TB" on March 26, 2009 during the 4th Annual User Meeting

  14. Enterprise Assessments Follow-up Assessment of Safety Culture...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Assessment of Safety Culture at the Hanford Site Waste Treatment and Immobilization Plant - June 2015 Enterprise Assessments Follow-up Assessment of Safety Culture at the Hanford...

  15. Method and apparatus for biological sequence comparison

    DOE Patents [OSTI]

    Marr, T.G.; Chang, W.I.

    1997-12-23

    A method and apparatus are disclosed for comparing biological sequences from a known source of sequences, with a subject (query) sequence. The apparatus takes as input a set of target similarity levels (such as evolutionary distances in units of PAM), and finds all fragments of known sequences that are similar to the subject sequence at each target similarity level, and are long enough to be statistically significant. The invention device filters out fragments from the known sequences that are too short, or have a lower average similarity to the subject sequence than is required by each target similarity level. The subject sequence is then compared only to the remaining known sequences to find the best matches. The filtering member divides the subject sequence into overlapping blocks, each block being sufficiently large to contain a minimum-length alignment from a known sequence. For each block, the filter member compares the block with every possible short fragment in the known sequences and determines a best match for each comparison. The determined set of short fragment best matches for the block provide an upper threshold on alignment values. Regions of a certain length from the known sequences that have a mean alignment value upper threshold greater than a target unit score are concatenated to form a union. The current block is compared to the union and provides an indication of best local alignment with the subject sequence. 5 figs.

  16. Method and apparatus for biological sequence comparison

    DOE Patents [OSTI]

    Marr, Thomas G.; Chang, William I-Wei

    1997-01-01

    A method and apparatus for comparing biological sequences from a known source of sequences, with a subject (query) sequence. The apparatus takes as input a set of target similarity levels (such as evolutionary distances in units of PAM), and finds all fragments of known sequences that are similar to the subject sequence at each target similarity level, and are long enough to be statistically significant. The invention device filters out fragments from the known sequences that are too short, or have a lower average similarity to the subject sequence than is required by each target similarity level. The subject sequence is then compared only to the remaining known sequences to find the best matches. The filtering member divides the subject sequence into overlapping blocks, each block being sufficiently large to contain a minimum-length alignment from a known sequence. For each block, the filter member compares the block with every possible short fragment in the known sequences and determines a best match for each comparison. The determined set of short fragment best matches for the block provide an upper threshold on alignment values. Regions of a certain length from the known sequences that have a mean alignment value upper threshold greater than a target unit score are concatenated to form a union. The current block is compared to the union and provides an indication of best local alignment with the subject sequence.

  17. Reversibly immobilized biological materials in monolayer films on electrodes

    DOE Patents [OSTI]

    Weaver, P.F.; Frank, A.J.

    1993-05-04

    Methods and techniques are described for reversibly binding charged biological particles in a fluid medium to an electrode surface. The methods are useful in a variety of applications. The biological materials may include microbes, proteins, and viruses. The electrode surface may consist of reversibly electroactive materials such as polyvinylferrocene, silicon-linked ferrocene or quinone.

  18. Reversibly immobilized biological materials in monolayer films on electrodes

    DOE Patents [OSTI]

    Weaver, Paul F. (Golden, CO); Frank, Arthur J. (Lakewood, CO)

    1993-01-01

    Methods and techniques are described for reversibly binding charged biological particles in a fluid medium to an electrode surface. The methods are useful in a variety of applications. The biological materials may include microbes, proteins, and viruses. The electrode surface may consist of reversibly electroactive materials such as polyvinylferrocene, silicon-linked ferrocene or quinone.

  19. Concentration and separation of biological organisms by ultrafiltration and

    Office of Scientific and Technical Information (OSTI)

    dielectrophoresis (Patent) | DOEPatents Concentration and separation of biological organisms by ultrafiltration and dielectrophoresis Title: Concentration and separation of biological organisms by ultrafiltration and dielectrophoresis Disclosed is a method for monitoring sources of public water supply for a variety of pathogens by using a combination of ultrafiltration techniques together dielectrophoretic separation techniques. Because water-borne pathogens, whether present due to

  20. Quality Procedure - Management Assessment and Self-Assessment | Department

    Energy Savers [EERE]

    of Energy Management Assessment and Self-Assessment Quality Procedure - Management Assessment and Self-Assessment This procedure establishes the roles, responsibilities, requirements, and process for conducting Environmental Management (EM) Office of Standards and Quality Assurance management assessments and self-assessments. Effective management assessments and self-assessments are built on self-evaluation, work process analysis, clear communication with management, and honest feedback that

  1. TECHNOLOGY READINESS ASSESSMENT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ASSESSMENT JANUARY 2015 -A CHECKPOINT ALONG A CHALLENGING JOURNEY DOE/NETL-2015/1710 U.S. Department of Energy 2014 TECHNOLOGY READINESS ASSESSMENT-CLEAN COAL RESEARCH PROGRAM 2 2014 TECHNOLOGY READINESS ASSESSMENT-CLEAN COAL RESEARCH PROGRAM Office of Fossil Energy | National Energy Technology Laboratory DISCLAIMER 3 DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor

  2. TECHNOLOGY READINESS ASSESSMENT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DECEMBER 2012 Pathway for readying the next generation of affordable clean energy technology -Carbon Capture, Utilization, and Storage (CCUS) 2012 TECHNOLOGY READINESS ASSESSMENT -OVERVIEW 2 2012 TECHNOLOGY READINESS ASSESSMENT-OVERVIEW 2012 TECHNOLOGY READINESS ASSESSMENT-OVERVIEW 3 DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any

  3. Management of Biological Materials in Wastewater from Research & Development Facilities

    SciTech Connect (OSTI)

    Raney, Elizabeth A.; Moon, Thomas W.; Ballinger, Marcel Y.

    2011-04-01

    PNNL has developed and instituted a systematic approach to managing work with biological material that begins in the project planning phase and carries through implementation to waste disposal. This paper describes two major processes used at PNNL to analyze and mitigate the hazards associated with working with biological materials and evaluate them for disposal to the sewer, ground, or surface water in a manner that protects human health and the environment. The first of these processes is the Biological Work Permit which is used to identify requirements for handling, storing, and working with biological materials and the second is the Sewer Approval process which is used to evaluate discharges of wastewaters containing biological materials to assure they meet industrial wastewater permits and other environmental regulations and requirements.

  4. SCADA Vulnerability Assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... SCADA Images Since 1999, Sandia has conducted numerous assessments of SCADA and process control systems in hydroelectric dams; water treatment systems; electric power transmission, ...

  5. Advances in Performance Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    safety of geologic repositories for radioactive waste disposal called "performance assessment", PA. The discipline of PA continues to advance within the Defense Waste Management...

  6. Hoisting & Rigging Assessment Form

    Broader source: Energy.gov [DOE]

      Assess the institutional and department/division hoisting and rigging (including forklift, overhead cranes small hoists, and mobile cranes) requirements, policies, procedures, and work practices...

  7. Environmental Risk Assessment

    Broader source: Energy.gov [DOE]

    PPPO subject-matter experts analyze possible environmental hazards and provide risk assessment information to help inform various environmental decision-making processes.

  8. Southern Appalachian assessment. Summary report, Report 1 of 5

    SciTech Connect (OSTI)

    1996-07-01

    This final report for the Southern Appalachian Man and the Biosphere Program is comprised of two documents: (1) a brief summary of programs and projects, and (2) a more extensive summary report included as an attachment. The purpose of the program is to promote a sustainable balance between the conservation of biological diversity, compatible economic uses, and cultural values across the Southern Appalachians. Program and project areas addressing regional issues include environmental monitoring and assessment, sustainable development/sustainable technologies, conservation biology, ecosystem management, environmental education and training, cultural and historical resources, and public information and education. The attached summary report is one of five that documents the results of the Southern Appalachian Assessment; it includes atmospheric, social/cultural/economic, terrestrial, and aquatic reports.

  9. Molecular biology of Homo sapiens: Abstracts of papers presented at the 51st Cold Spring Harbor symposium on quantitative biology

    SciTech Connect (OSTI)

    Watson, J.D.; Siniscalco, M.

    1986-01-01

    This volume contains abstracts of papers presented at the 51st Cold Springs Harbor Symposium on Quantitative Biology. The topic for this meeting was the ''Molecular Biology of Homo sapiens.'' Sessions were entitled Human Gene Map, Human Cancer Genes, Genetic Diagnosis, Human Evolution, Drugs Made Off Human Genes, Receptors, and Gene Therapy. (DT)

  10. Systems Biology Knowledgebase for a New Era in Biology A Genomics:GTL Report from the May 2008 Workshop

    SciTech Connect (OSTI)

    Gregurick, S.; Fredrickson, J. K.; Stevens, R.

    2009-03-01

    Biology has entered a systems-science era with the goal to establish a predictive understanding of the mechanisms of cellular function and the interactions of biological systems with their environment and with each other. Vast amounts of data on the composition, physiology, and function of complex biological systems and their natural environments are emerging from new analytical technologies. Effectively exploiting these data requires developing a new generation of capabilities for analyzing and managing the information. By revealing the core principles and processes conserved in collective genomes across all biology and by enabling insights into the interplay between an organism's genotype and its environment, systems biology will allow scientific breakthroughs in our ability to project behaviors of natural systems and to manipulate and engineer managed systems. These breakthroughs will benefit Department of Energy (DOE) missions in energy security, climate protection, and environmental remediation.

  11. Cape Verde: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    0.00 Quadrillion Btu 2-letter ISO code CV 3-letter ISO code CPV Numeric ISO code 132 UN Region1 Western Africa OpenEI Resources Energy Maps 0 Tools 0 Programs 4 view...

  12. Biologically based multistage modeling of radiation effects

    SciTech Connect (OSTI)

    William Hazelton; Suresh Moolgavkar; E. Georg Luebeck

    2005-08-30

    This past year we have made substantial progress in modeling the contribution of homeostatic regulation to low-dose radiation effects and carcinogenesis. We have worked to refine and apply our multistage carcinogenesis models to explicitly incorporate cell cycle states, simple and complex damage, checkpoint delay, slow and fast repair, differentiation, and apoptosis to study the effects of low-dose ionizing radiation in mouse intestinal crypts, as well as in other tissues. We have one paper accepted for publication in ''Advances in Space Research'', and another manuscript in preparation describing this work. I also wrote a chapter describing our combined cell-cycle and multistage carcinogenesis model that will be published in a book on stochastic carcinogenesis models edited by Wei-Yuan Tan. In addition, we organized and held a workshop on ''Biologically Based Modeling of Human Health Effects of Low dose Ionizing Radiation'', July 28-29, 2005 at Fred Hutchinson Cancer Research Center in Seattle, Washington. We had over 20 participants, including Mary Helen Barcellos-Hoff as keynote speaker, talks by most of the low-dose modelers in the DOE low-dose program, experimentalists including Les Redpath (and Mary Helen), Noelle Metting from DOE, and Tony Brooks. It appears that homeostatic regulation may be central to understanding low-dose radiation phenomena. The primary effects of ionizing radiation (IR) are cell killing, delayed cell cycling, and induction of mutations. However, homeostatic regulation causes cells that are killed or damaged by IR to eventually be replaced. Cells with an initiating mutation may have a replacement advantage, leading to clonal expansion of these initiated cells. Thus we have focused particularly on modeling effects that disturb homeostatic regulation as early steps in the carcinogenic process. There are two primary considerations that support our focus on homeostatic regulation. First, a number of epidemiologic studies using multistage carcinogenesis models that incorporate the ''initiation, promotion, and malignant conversion'' paradigm of carcinogenesis are indicating that promotion of initiated cells is the most important cellular mechanism driving the shape of the age specific hazard for many types of cancer. Second, we have realized that many of the genes that are modified in early stages of the carcinogenic process contribute to one or more of four general cellular pathways that confer a promotional advantage to cells when these pathways are disrupted.

  13. Risk assessment and management of radiofrequency radiation exposure

    SciTech Connect (OSTI)

    Dabala, Dana; Surducan, Emanoil; Surducan, Vasile; Neamtu, Camelia

    2013-11-13

    Radiofrequency radiation (RFR) industry managers, occupational physicians, security department, and other practitioners must be advised on the basic of biophysics and the health effects of RF electromagnetic fields so as to guide the management of exposure. Information on biophysics of RFR and biological/heath effects is derived from standard texts, literature and clinical experiences. Emergency treatment and ongoing care is outlined, with clinical approach integrating the circumstances of exposure and the patient's symptoms. Experimental risk assessment model in RFR chronic exposure is proposed. Planning for assessment and monitoring exposure, ongoing care, safety measures and work protection are outlining the proper management.

  14. Kinetic model for anaerobic digestion of biogas biological sludge

    SciTech Connect (OSTI)

    Pavlostathis, S.G.; Gossett, J.M.

    1986-10-01

    The principal objective of this study was the development and evaluation of a comprehensive kinetic model capable of predicting digester performance when fed biological sludge. Preliminary conversion mechanisms such as cell deaths, lysis, and hydrolysis responsible for rendering viable biological sludge organisms to available substrate were studied in depth. The results of this study indicate that hydrolysis of the dead, particulate biomass - primarily consisting of protein - is the slowest step, and therefore kinetically controls the overall process of an anaerobic digestion of biological sludge. A kinetic model was developed which could accurately describe digester performance and predict effluent quality.

  15. Integrated assessment briefs

    SciTech Connect (OSTI)

    1995-04-01

    Integrated assessment can be used to evaluate and clarify resource management policy options and outcomes for decision makers. The defining characteristics of integrated assessment are (1) focus on providing information and analysis that can be understood and used by decision makers rather than for merely advancing understanding and (2) its multidisciplinary approach, using methods, styles of study, and considerations from a broader variety of technical areas than would typically characterize studies produced from a single disciplinary standpoint. Integrated assessment may combine scientific, social, economic, health, and environmental data and models. Integrated assessment requires bridging the gap between science and policy considerations. Because not everything can be valued using a single metric, such as a dollar value, the integrated assessment process also involves evaluating trade-offs among dissimilar attributes. Scientists at Oak Ridge National Laboratory (ORNL) recognized the importance and value of multidisciplinary approaches to solving environmental problems early on and have pioneered the development of tools and methods for integrated assessment over the past three decades. Major examples of ORNL`s experience in the development of its capabilities for integrated assessment are given.

  16. NERSC Operational Assessment Review

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NERSC Operational Assessment Review Agenda and Logistics Home » Events » HPC Workshops » NERSC Operational Assessment Review NERSC Operational Assessment Review By invitation only. Agenda TUESDAY, FEBRUARY 16 8am - Coffee and Pastries 8:15am: Welcome and logistics - Katie Antypas 8:20am: Welcome and DOE charge - Dave Goodwin 8:30am - 9:15am:Year in Review - Sudip Dosanjh 9:30am - 10:30am: User Results - Katie Antypas 10:45 - 11:am: Break 11:00-11:45: Science and Strategic Results - Richard

  17. Energy Assessments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Assessments Energy Assessments PDF icon Unveiling the Implementation Guide (October 11, 2011) PDF icon webcast_2009-0409_common_recommendations.pdf PDF icon webcast_2009-0219_small_medium_assessment_benefits.pdf PDF icon webcast_2009-0212_large plant_assessments.pdf PDF icon webcast_2008-1106_small_medium_assessments.pdf PDF icon large_assessments_webcast_10-16-08.pdf More Documents & Publications Unveiling the Implementation Guide Industrial Energy Efficiency Assessments IAC

  18. Arms Control: US and International efforts to ban biological weapons

    SciTech Connect (OSTI)

    Not Available

    1992-12-01

    The Bacteriological (Biological) and Toxin Weapons Convention, the treaty that bans the development, production, and stockpiling and acquisition of biological weapons was opened for signature in 1972 and came into force in 1975 after being ratified by 22 governments, including the depository nations of the USA, the United Kingdom, and the former Soviet Union. In support of the Convention, the USA later established export controls on items used to make biological weapons. Further, in accordance with the 1990 President`s Enhanced Proliferation Control Initiative, actions were taken to redefine and expand US export controls, as well as to encourage multilateral controls through the Australia Group. Thus far, the Convention has not been effective in stopping the development of biological weapons. The principal findings as to the reasons of the failures of the Convention are found to be: the Convention lacks universality, compliance measures are effective, advantage of verification may outweigh disadvantages. Recommendations for mitigating these failures are outlined in this report.

  19. EA-2011: Proposed Release of Three Parasitoids for the Biological...

    Broader source: Energy.gov (indexed) [DOE]

    the continental U.S. for the biological control of the emerald ash borer, a nonnative invasive beetle. The DOE Oak Ridge Office reviewed the EA, adopted it, and issued a FONSI for...

  20. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2014-10-28

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  1. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2014-05-27

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  2. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2015-04-14

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  3. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2013-10-01

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  4. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in...

  5. John Marohn > ProfessorChemistry and Chemical Biology > Faculty...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Marohn Professor Chemistry and Chemical Biology Research Group Webpage jam99@cornell.edu John Marohn earned a B.S. in Chemistry and a B.A. in Physics from the University of...

  6. Biology Chemistry & Material Science Laboratory 2 | Sample Preparation...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2 Cynthia Patty | (650) 926-3925 Biology Chemistry & Material Science Laboratory 2 Inventory The BioChemMat Lab 2 (BCM 2) at SSRL is dedicated to researcher experiments, including...

  7. Biology Chemistry & Material Science Laboratory 1 | Sample Preparation...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1 Cynthia Patty | (650) 926-3925 Biology Chemistry & Material Science Laboratory 1 Inventory The BioChemMat Lab 1 at SSRL is dedicated to researcher experiments, including x-ray...

  8. Investigations of biological processes in Austrian MBT plants

    SciTech Connect (OSTI)

    Tintner, J.; Smidt, E.; Boehm, K.; Binner, E.

    2010-10-15

    Mechanical biological treatment (MBT) of municipal solid waste (MSW) has become an important technology in waste management during the last decade. The paper compiles investigations of mechanical biological processes in Austrian MBT plants. Samples from all plants representing different stages of degradation were included in this study. The range of the relevant parameters characterizing the materials and their behavior, e.g. total organic carbon, total nitrogen, respiration activity and gas generation sum, was determined. The evolution of total carbon and nitrogen containing compounds was compared and related to process operation. The respiration activity decreases in most of the plants by about 90% of the initial values whereas the ammonium release is still ongoing at the end of the biological treatment. If the biogenic waste fraction is not separated, it favors humification in MBT materials that is not observed to such extent in MSW. The amount of organic carbon is about 15% dry matter at the end of the biological treatment.

  9. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their...

  10. September 2013 Most Viewed Documents for Biology And Medicine...

    Office of Scientific and Technical Information (OSTI)

    September 2013 Most Viewed Documents for Biology And Medicine Science Subject Feed Drug ... KRISHNA,C.R. (1999) 27 > Site-Directed Research and Development FY 2012 Annual Report , ...

  11. Browse by Discipline -- E-print Network Subject Pathways: Biology...

    Office of Scientific and Technical Information (OSTI)

    L M N O P Q R S T U V W X Y Z Keller, Christopher (Christopher Keller) - Department of Biology, Minot State University Go back to Individual Researchers Collections: A B C D E F G ...

  12. A comprehensive approach to decipher biological computation to achieve next

    Office of Scientific and Technical Information (OSTI)

    generation high-performance exascale computing. (Technical Report) | SciTech Connect A comprehensive approach to decipher biological computation to achieve next generation high-performance exascale computing. Citation Details In-Document Search Title: A comprehensive approach to decipher biological computation to achieve next generation high-performance exascale computing. The human brain (volume=1200cm3) consumes 20W and is capable of performing>10%5E16 operations/s. Current

  13. Importance of systems biology in engineering microbes for biofuel

    Office of Scientific and Technical Information (OSTI)

    production (Journal Article) | SciTech Connect Importance of systems biology in engineering microbes for biofuel production Citation Details In-Document Search Title: Importance of systems biology in engineering microbes for biofuel production Microorganisms have been rich sources for natural products, some of which have found use as fuels, commodity chemicals, specialty chemicals, polymers, and drugs, to name a few. The recent interest in production of transportation fuels from renewable

  14. Integration of Hyperspectral Imagery and Biosensors for Biological and

    Office of Scientific and Technical Information (OSTI)

    Chemical Facility Classification (Technical Report) | SciTech Connect Hyperspectral Imagery and Biosensors for Biological and Chemical Facility Classification Citation Details In-Document Search Title: Integration of Hyperspectral Imagery and Biosensors for Biological and Chemical Facility Classification Authors: Munsky, Brian [1] ; Yeager, John D. [1] ; Sellars, Scott [2] ; Mukundan, Harshini [1] ; Nadler, Brett Ross [1] + Show Author Affiliations Los Alamos National Laboratory UC Irvine

  15. Integration of Hyperspectral Imagery and Biosensors for Biological and

    Office of Scientific and Technical Information (OSTI)

    Chemical Facility Classification (Technical Report) | SciTech Connect Hyperspectral Imagery and Biosensors for Biological and Chemical Facility Classification Citation Details In-Document Search Title: Integration of Hyperspectral Imagery and Biosensors for Biological and Chemical Facility Classification × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided

  16. Integration of hyperspectral imagery and biosensors for biological and

    Office of Scientific and Technical Information (OSTI)

    chemical facility classification (Technical Report) | SciTech Connect hyperspectral imagery and biosensors for biological and chemical facility classification Citation Details In-Document Search Title: Integration of hyperspectral imagery and biosensors for biological and chemical facility classification Authors: Munsky, Brian [1] ; Sellars, Scott [2] ; Yeager, John D. [1] ; Mukundan, Harshini [1] ; Nadler, Brett Ross [1] + Show Author Affiliations Los Alamos National Laboratory UC Irvine

  17. Integration of hyperspectral imagery and biosensors for biological and

    Office of Scientific and Technical Information (OSTI)

    chemical facility classification (Technical Report) | SciTech Connect hyperspectral imagery and biosensors for biological and chemical facility classification Citation Details In-Document Search Title: Integration of hyperspectral imagery and biosensors for biological and chemical facility classification × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided

  18. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure The Biological Implications of the PP2A Crystal Structure Print Wednesday, 30 January 2008 00:00 Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a

  19. Biological and Catalytic Conversion of Sugars and Lignin | Bioenergy | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological and Catalytic Conversion of Sugars and Lignin Our research group, comprised of staff scientists, postdoctoral associates, students, and technicians, develops biological and chemical catalysts for cost-effective production of fuels and chemicals from terrestrial biomass. Two side-by-side images. The left figure illustrates the domains of the synthase enzyme, represented as "surfaces" or "blobs," embedded in a lipid bilayer, represented as yellow multi-jointed

  20. A Systems Biology Platform for Characterizing Regulatory and Metabolic

    Office of Scientific and Technical Information (OSTI)

    Pathways that Influence and Control Microbial Hydrogen Production (Technical Report) | SciTech Connect Technical Report: A Systems Biology Platform for Characterizing Regulatory and Metabolic Pathways that Influence and Control Microbial Hydrogen Production Citation Details In-Document Search Title: A Systems Biology Platform for Characterizing Regulatory and Metabolic Pathways that Influence and Control Microbial Hydrogen Production Authors: Collins, James J [1] + Show Author Affiliations

  1. A comprehensive approach to decipher biological computation to achieve next

    Office of Scientific and Technical Information (OSTI)

    generation high-performance exascale computing. (Technical Report) | SciTech Connect Technical Report: A comprehensive approach to decipher biological computation to achieve next generation high-performance exascale computing. Citation Details In-Document Search Title: A comprehensive approach to decipher biological computation to achieve next generation high-performance exascale computing. The human brain (volume=1200cm3) consumes 20W and is capable of performing>10%5E16 operations/s.

  2. Ringleader: Jay Nix, Beamline Director for the Molecular Biology Consortium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ringleader: Jay Nix, Beamline Director for the Molecular Biology Consortium Print Jay Nix started started the user program at Beamline 4.2.2 back in 2004, shortly after the Molecular Biology Consortium built the beamline. The macromolecular crystallography beamline is a little different than most at the ALS because it's privately managed by a consortium of 10 Midwest universities that pooled their money together to build the beamline, and now continue to do so to maintain it. Nix serves about 50

  3. Ringleader: Jay Nix, Beamline Director for the Molecular Biology Consortium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jay Nix, Beamline Director for the Molecular Biology Consortium Print Jay Nix started started the user program at Beamline 4.2.2 back in 2004, shortly after the Molecular Biology Consortium built the beamline. The macromolecular crystallography beamline is a little different than most at the ALS because it's privately managed by a consortium of 10 Midwest universities that pooled their money together to build the beamline, and now continue to do so to maintain it. Nix serves about 50 labs,

  4. Excitonic Quantum Random Walk in Biological Phycocyanin Nanowires |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MIT-Harvard Center for Excitonics Quantum Random Walk in Biological Phycocyanin Nanowires October 6, 2015 at 4:30pm/ 36-428 Yossi Paltiel Department of Applied Physics, The Hebrew University of Jerusalem yossi-3a The importance of quantum processes in biology is starting to be recognized. Quantum processes are being discussed in the context of enzyme function, olfaction, magnetic sensing and most prominently in photosynthetic light-harvesting complexes. These findings suggest that a key to

  5. Flow cytometry aids basic cell biology research and drug discovery

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Flow cytometry aids basic cell biology research and drug discovery Flow cytometry aids basic cell biology research and drug discovery Life Technologies Corporation and LANL have released the Attune® Acoustic Focusing Cytometer, featuring a reduced footprint, reduced consumables, and an affordable price. April 3, 2012 Attune® Acoustic Focusing Cytometer The Attune® Acoustic Focusing Cytometer achieves sample throughput at rates over 10 times faster than other cytometers-up to 1,000 μL per

  6. Comparative systems biology across an evolutionary gradient within the

    Office of Scientific and Technical Information (OSTI)

    Shewanella genus (Journal Article) | SciTech Connect Comparative systems biology across an evolutionary gradient within the Shewanella genus Citation Details In-Document Search Title: Comparative systems biology across an evolutionary gradient within the Shewanella genus To what extent genotypic differences translate to phenotypic variation remains a poorly understood issue of paramount importance for several cornerstone concepts of microbiology such as the species definition. Here, we take

  7. Copy of Synthetic Biology of Novel Thermophilic Bacteria for Enhanced

    Office of Scientific and Technical Information (OSTI)

    Production of Ethanol from 5-Carbon Sugars (LDRD %23 105944). (Conference) | SciTech Connect Copy of Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of Ethanol from 5-Carbon Sugars (LDRD %23 105944). Citation Details In-Document Search Title: Copy of Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of Ethanol from 5-Carbon Sugars (LDRD %23 105944). Abstract not provided. Authors: Reichmuth, David ; Kozina, Carol L. ; Sale, Kenneth L. ;

  8. New Microbiome Center to combine UChicago, Marine Biological Laboratory and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Argonne expertise | Argonne National Laboratory Filamentous cyanobacteria from a tidal pond at Little Sippewissett salt marsh, Falmouth, Mass. Microbial communities - bacteria, viruses and fungi - affect every ecosystem on earth, including human bodies, oceans, our homes and the land around us, and are the focus of a new Microbiome Center jointly headed by Argonne, the Marine Biological Laboratory and the University of Chicago. (Image: S. Emil Ruff, Marine Biological Laboratory) Filamentous

  9. Large Scale Production Computing and Storage Requirements for Biological

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Environmental Research: Target 2017 Large Scale Production Computing and Storage Requirements for Biological and Environmental Research: Target 2017 BERmontage.gif September 11-12, 2012 Hilton Rockville Hotel and Executive Meeting Center 1750 Rockville Pike Rockville, MD, 20852-1699 TEL: 1-301-468-1100 Sponsored by: U.S. Department of Energy Office of Science Office of Advanced Scientific Computing Research (ASCR) Office of Biological and Environmental Research (BER) National Energy

  10. Computational Biology: A Recipe for Ligand-Binding Proteins

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computational Biology: A Recipe for Ligand-Binding Proteins Authors: Ghirlanda, G. Title: Computational Biology: A Recipe for Ligand-Binding Proteins Source: Nature Year: 2013 Volume: 501 Pages: 177-178 ABSTRACT: Cellular cross-talk, enzymatic catalysis and regulation of gene expression all depend on molecular recognition. A method that allows the design of proteins with desired recognition sites could thus be revolutionary Date of online publication: Thu, 2013-09-12 Link online:

  11. Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of

    Office of Scientific and Technical Information (OSTI)

    Ethanol from 5-Carbon Sugars (LDRD %23 105944). (Conference) | SciTech Connect Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of Ethanol from 5-Carbon Sugars (LDRD %23 105944). Citation Details In-Document Search Title: Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of Ethanol from 5-Carbon Sugars (LDRD %23 105944). Abstract not provided. Authors: Sapra, Rajat ; Reichmuth, David ; Kozina, Carol L. ; Sale, Kenneth L. ; Keasling, Jay ; Tang,

  12. Technical Assessment Team Report

    Broader source: Energy.gov [DOE]

    The Technical Assessment Team (TAT) is an independent team of technical experts that evaluated the mechanisms and chemical reactions contributing to the failure of a waste drum at the Waste...

  13. Assessing Renewable Energy Options

    Broader source: Energy.gov [DOE]

    Federal agencies should assess renewable energy options for each specific project when integrating renewable energy in new building construction or major renovations. This section covers the preliminary screening, screening, feasibility study, and sizing and designing systems phases.

  14. Technology Readiness Assessment Guide

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2011-09-15

    The Guide assists individuals and teams involved in conducting Technology Readiness Assessments (TRAs) and developing Technology Maturation Plans (TMPs) for the DOE capital asset projects subject to DOE O 413.3B. Supersedes DOE G 413.3-4.

  15. Environmental assessment of remedial action at the Maybell uranium mill tailings site near Maybell, Colorado

    SciTech Connect (OSTI)

    Not Available

    1993-09-01

    The purpose of this environmental assessment (EA) is to evaluate the environmental impacts resulting from remedial action at the Maybell uranium mill tailings site near Maybell, Colorado. A biological assessment (Attachment 1) and a floodplain/wetlands assessment (Assessment 2) are included as part of this EA. The following sections and attachments describe the proposed action, affected environment, and environmental impacts associated with the proposed remedial action, including impacts to threatened and endangered species listed or proposed for listing by the US Fish and Wildlife Service.

  16. Culture, and a Metrics Methodology for Biological Countermeasure Scenarios

    SciTech Connect (OSTI)

    Simpson, Mary J.

    2007-03-15

    Outcome Metrics Methodology defines a way to evaluate outcome metrics associated with scenario analyses related to biological countermeasures. Previous work developed a schema to allow evaluation of common elements of impacts across a wide range of potential threats and scenarios. Classes of metrics were identified that could be used by decision makers to differentiate the common bases among disparate scenarios. Typical impact metrics used in risk calculations include the anticipated number of deaths, casualties, and the direct economic costs should a given event occur. There are less obvious metrics that are often as important and require more intensive initial work to be incorporated. This study defines a methodology for quantifying, evaluating, and ranking metrics other than direct health and economic impacts. As has been observed with the consequences of Hurricane Katrina, impacts to the culture of specific sectors of society are less obvious on an immediate basis but equally important over the ensuing and long term. Culture is used as the example class of metrics within which • requirements for a methodology are explored • likely methodologies are examined • underlying assumptions for the respective methodologies are discussed • the basis for recommending a specific methodology is demonstrated. Culture, as a class of metrics, is shown to consist of political, sociological, and psychological elements that are highly valued by decision makers. In addition, cultural practices, dimensions, and kinds of knowledge offer complementary sets of information that contribute to the context within which experts can provide input. The quantification and evaluation of sociopolitical, socio-economic, and sociotechnical impacts depend predominantly on subjective, expert judgment. Epidemiological data is limited, resulting in samples with statistical limits. Dose response assessments and curves depend on the quality of data and its relevance to human modes of exposure. With uncertain data and limited common units, the aggregation of results is not inherently obvious. Candidate methodologies discussed include statistical, analytical, and expert-based numerical approaches. Most statistical methods require large amounts of data with a random distribution of values for validity. Analytical methods predominate wherein structured data or patterns are evident and randomness is low. The analytical hierarchy process is shown to satisfy all requirements and provide a detailed method for measurement that depends on expert judgment by decision makers.

  17. PRIVACY IMPACT ASSESSMENT: Office

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office of Information Resources - FOIAXpress Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetext/neword/206/02061.pdf Please complete electronically: no hand-written submissions will be accepted. This template may not be modified. MODULE 1- PRIVACY

  18. PRIVACY IMPACT ASSESSMENT: Office

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office of Workforce Development for Teachers and Scientists Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextineword/206/o2061.pdf Please complete electronically: no hand-written submissions will be accepted. This template may not be modified. MODULE

  19. DOEEA-0984 Environmental Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DOEEA-0984 Environmental Assessment Environmental Assessment for the Deactivation of the N Reactor Facilities U.S. Department of Energy Richland, Washington May 1995 \ lR4DEMARK DISCLAIMER Reference herein to any specific wmmercial product, process. M m M c e by trade name, uademark, manufacturer. or otherwise, does not necessariiy collbuNte M imply ~ f s endorsement, rewmmendation. or favoring by the Unrted States Government or any agency thereof or I u Contractors M subcontractors Ths repon

  20. Pumping System Assessment Tool

    Broader source: Energy.gov [DOE]

    The Pumping System Assessment Tool (PSAT) is a free online software tool to help industrial users assess the efficiency of pumping system operations. PSAT uses achievable pump performance data from Hydraulic Institute standards and motor performance data from the MotorMaster+ database to calculate potential energy and associated cost savings. The tool also enables users to save and retrieve log files, default values, and system curves for sharing analyses with other users.

  1. Behavior of nanoceria in biologically-relevant environments

    SciTech Connect (OSTI)

    Kumar, Amit; Das, Soumen; Munusamy, Prabhakaran; Self, William; Baer, Donald R.; Sayle, Dean C.; Seal, Sudipta

    2014-09-08

    Cerium oxide nanoparticles (CNPs) have gained a considerable attention in biological research due to their anti-oxidant like behaviour and regenerative nature. The current literature on CNPs reports many successful attempts on harnessing the beneficial therapeutic properties in biology. However studies have also shown toxicity effect with some types of CNPs. This review discusses issues associated with the behaviours of CNPs in biological systems and identifies key knowledge gaps. We explore how salient physicochemical properties (size, surface chemistry, surface stabilizers) contribute to the potential positive and negative aspects of nanoceria in biological systems. Based on variations of results reported in the literature, important issues need to be addressed. Are we really studying the same particles with slight variations in size and physicochemical properties or do the particles being examined have fundamentally different behaviours? Are the variations observed in the result of differences in the initial properties of the particles or the results of downstream effects that emerge as the particles are prepared for specific studies and they interact with biological or other environmental moieties? How should particles be appropriately prepared for relevant environmental/toxicology/safety studies? It is useful to recognize that nanoparticles encompass some of the same complexities and variability associated with biological components

  2. Enterprise Assessments Emergency Management Assessment of the Waste

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Isolation Pilot Plant - April 2016 | Department of Energy Emergency Management Assessment of the Waste Isolation Pilot Plant - April 2016 Enterprise Assessments Emergency Management Assessment of the Waste Isolation Pilot Plant - April 2016 April 2016 Emergency Management Assessment of the Waste Isolation Pilot Plant - April 2016 The Office of Emergency Management Assessments, within the U.S. Department of Energy (DOE) independent Office of Enterprise Assessments (EA), conducted an

  3. Environmental assessment of remedial action at the Maybell uranium mill tailings site near Maybell, Colorado: Revision 2

    SciTech Connect (OSTI)

    Not Available

    1994-11-01

    The purpose of this environmental assessment (EA) is to evaluate the environmental impacts resulting from remedial action at the Maybell uranium mill tailings site near Maybell, Colorado. A biological assessment and a floodplain/wetlands assessment are included as part of this EA. This report and attachments describe the proposed action, affected environment, and environmental impacts associated with the proposed remedial action, including impacts to threatened and endangered species listed or proposed for listing by the US Fish and Wildlife Service (FWS).

  4. Bonneville - Hood River Vegetation Management Environmental Assessment

    SciTech Connect (OSTI)

    N /A

    1998-08-01

    To maintain the reliability of its electrical system, BPA, in cooperation with the U.S. Forest Service, needs to expand the range of vegetation management options used to clear unwanted vegetation on about 20 miles of BPA transmission line right-of-way between Bonneville Dam and Hood River; Oregon, within the Columbia Gorge National Scenic Area (NSA). We propose to continue controlling undesirable vegetation using a program of Integrated Vegetation Management (IVM) which includes manual, biological and chemical treatment methods. BPA has prepared an Environmental Assessment (EA) (DOE/EA-1257) evaluating the proposed project. Based on the analysis in the EA, BPA has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement (EIS) is not required and BPA is issuing this FONSI.

  5. Tobacco mosaic virus: A biological building block for micro/nano...

    Office of Scientific and Technical Information (OSTI)

    Tobacco mosaic virus: A biological building block for micronanobio systems Citation Details In-Document Search Title: Tobacco mosaic virus: A biological building block for micro...

  6. Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects from Development Sage-Grouse and Wind Energy: Biology, Habits, and Potential Effects from Development ...

  7. Department of Defense Nuclear/Biological/Chemical (NBC) warfare defense. Annual report to Congress, June 1994. Final report, 1 October 1992-30 September 1993

    SciTech Connect (OSTI)

    Not Available

    1994-06-01

    The National Defense Authorization Act for Fiscal Year 1994, Public Law 103-160, Title XVII, Chemical and Biological Weapons Defense, section 1703, directed the Secretary of Defense to submit an assessment and a description of plans to improve readiness. The DoD objective is to enable our forces to survive, fight and win in NBC contaminated environments. Discussed are new management objectives impacted by declining resources and force structure versus an ever changing threat environment. Nuclear biological, Chemical, NBC, Defense, Logistics, Readiness, Training, Contamination avoidance, Protection, Decontamination.

  8. Performance Assessment | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Assessment Performance Assessment Performance Assessment The Office of Project Management Oversight and Assessments (PM) provides a monthly assessment of DOE's portfolio of capital assets projects, which is summarized in the monthly Project Dashboard report. The current portfolio consists of 34 active projects with established scope, schedule, and cost performance baselines. Based on current performance, projects that are expected to meet their performance baseline are assessed as GREEN,

  9. Small Wind Site Assessment Guidelines

    SciTech Connect (OSTI)

    Olsen, Tim; Preus, Robert

    2015-09-01

    Site assessment for small wind energy systems is one of the key factors in the successful installation, operation, and performance of a small wind turbine. A proper site assessment is a difficult process that includes wind resource assessment and the evaluation of site characteristics. These guidelines address many of the relevant parts of a site assessment with an emphasis on wind resource assessment, using methods other than on-site data collection and creating a small wind site assessment report.

  10. Information technology resources assessment

    SciTech Connect (OSTI)

    Stevens, D.F.

    1992-01-01

    This year`s Information Technology Resources Assessment (ITRA) is something of a departure from traditional practice. Past assessments have concentrated on developments in fundamental technology, particularly with respect to hardware. They form an impressive chronicle of decreasing cycle times, increasing densities, decreasing costs (or, equivalently, increasing capacity and capability per dollar spent), and new system architectures, with a leavening of operating systems and languages. Past assessments have aimed -- and succeeded -- at putting information technology squarely in the spotlight; by contrast, in the first part of this assessment, we would like to move it to the background, and encourage the reader to reflect less on the continuing technological miracles of miniaturization in space and time and more on the second- and third-order implications of some possible workplace applications of these miracles. This Information Technology Resources Assessment is intended to provide a sense of technological direction for planners in projecting the hardware, software, and human resources necessary to support the diverse IT requirements of the various components of the DOE community. It is also intended to provide a sense of our new understanding of the place of IT in our organizations.

  11. Information technology resources assessment

    SciTech Connect (OSTI)

    Stevens, D.F.

    1992-01-01

    This year's Information Technology Resources Assessment (ITRA) is something of a departure from traditional practice. Past assessments have concentrated on developments in fundamental technology, particularly with respect to hardware. They form an impressive chronicle of decreasing cycle times, increasing densities, decreasing costs (or, equivalently, increasing capacity and capability per dollar spent), and new system architectures, with a leavening of operating systems and languages. Past assessments have aimed -- and succeeded -- at putting information technology squarely in the spotlight; by contrast, in the first part of this assessment, we would like to move it to the background, and encourage the reader to reflect less on the continuing technological miracles of miniaturization in space and time and more on the second- and third-order implications of some possible workplace applications of these miracles. This Information Technology Resources Assessment is intended to provide a sense of technological direction for planners in projecting the hardware, software, and human resources necessary to support the diverse IT requirements of the various components of the DOE community. It is also intended to provide a sense of our new understanding of the place of IT in our organizations.

  12. SELECTING SPECIES FOR MARINE ASSESSMENT OF RADIONUCLIDES AROUND AMCHITKA: PLANNING FOR DIVERSE

    Office of Legacy Management (LM)

    Monitoring and Assessment (2006) 123: 371-391 DOI: 10.1007/~10661-006-9203-2 @ Springer 2006 SELECTING SPECIES FOR MARINE ASSESSMENT OF RADIONUCLIDES AROUND AMCHITKA: PLANNING FOR DIVERSE GOALS AND INTERESTS JOANNA BURGER*, MICHAEL GOCHFELD and STEPHEN JEWETT Rutgers University ('author for correspondence, e-mail: burger@biology.rutgers.edu) (Received 27 October 2005; accepted 16 January 2006) Abstract. Considerable attention has been devoted to selecting bioindicator species as part of moni-

  13. Biosecurity Risk Assessment Methodology (BioRAM) v. 2.0

    Energy Science and Technology Software Center (OSTI)

    2009-06-08

    Sandia National Laboratories International Biological Threat Reduction Dept (SNL/IBTR) has an ongoing mission to enhance biosecurity assessment methodologies, tools, and guise. These will aid labs seeking to implement biosecurity as advocated in the recently released WHO's Biorisk Management: Lab Biosecurity Guidance. BioRAM 2.0 is the software tool developed initially using the SNL LDRD process and designed to complement the "Laboratory Biosecurity Risk Handbook" written by Ren Salerno and Jennifer Gaudioso defining biosecurity risk assessment methodologies.

  14. Assess Oportunities | Open Energy Information

    Open Energy Info (EERE)

    Assess Oportunities Jump to: navigation, search Stage 3 LEDS Home Introduction to Framework Assess current country plans, policies, practices, and capacities DevelopBAU Stage 4:...

  15. Assessment Documents | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Assessment, Y-12 National Security Complex - June 2012 Assessment of Nuclear Safety Culture at the Y-12 National Security Complex Uranium Processing Facility Project July 9,...

  16. Windows technology assessment

    SciTech Connect (OSTI)

    Baron, J.J.

    1995-10-01

    This assessment estimates that energy loss through windows is approximately 15 percent of all the energy used for space heating and cooling in residential and commercial buildings in New York State. The rule of thumb for the nation as a whole is about 25 percent. The difference may reflect a traditional assumption of single-pane windows while this assessment analyzed installed window types in the region. Based on the often-quoted assumption, in the United States some 3.5 quadrillion British thermal units (Btu) of primary energy, costing some $20 billion, is annually consumed as a result of energy lost through windows. According to this assessment, in New York State, the energy lost due to heat loss through windows is approximately 80 trillion Btu at an annual cost of approximately $1 billion.

  17. Solid-water detoxifying reagents for chemical and biological agents

    DOE Patents [OSTI]

    Hoffman, Dennis M.; Chiu, Ing Lap

    2006-04-18

    Formation of solid-water detoxifying reagents for chemical and biological agents. Solutions of detoxifying reagent for chemical and biological agents are coated using small quantities of hydrophobic nanoparticles by vigorous agitation or by aerosolization of the solution in the presence of the hydrophobic nanoparticles to form a solid powder. For example, when hydrophobic fumed silica particles are shaken in the presence of IN oxone solution in approximately a 95:5-weight ratio, a dry powder results. The hydrophobic silica forms a porous coating of insoluble fine particles around the solution. Since the chemical or biological agent tends to be hydrophobic on contact with the weakly encapsulated detoxifying solution, the porous coating breaks down and the detoxifying reagent is delivered directly to the chemical or biological agent for maximum concentration at the point of need. The solid-water (coated) detoxifying solutions can be blown into contaminated ventilation ducting or other difficult to reach sites for detoxification of pools of chemical or biological agent. Once the agent has been detoxified, it can be removed by flushing the area with air or other techniques.

  18. Request for Travel Funds for Systems Radiation Biology Workshop

    SciTech Connect (OSTI)

    Barcellos-Hoff, Mary Helen

    2014-03-22

    The 3rd International Systems Radiation Biology Workshop brought together the major European, US and Japanese research programs on radiation risk as well as selected experts representing systems biological approaches to discuss how the new methodologies could be best exploited for low dose research. A significant part of the workshop was devoted to discussions organised as breakout group sessions. To facilitate discussions number of participants was limited to 60 persons. To achieve the goals of this symposium in this international conference, support from DOE is vital. Hence, this proposal requested support in the amount of $15,000 to cover the travel expenses of international experts and radiation biology scientists from the United States. This supporting mechanism was clearly identified to the selected US participants as a conference support award from the DOE (See attached PDF). The workshop was an outstanding opportunity to strengthen interactions between leading experts in the emerging areas of radiation sciences, and will also provide opportunities for younger scientists to meet with experts and discuss their results. This workshop was designed to endorse active engagement in international collaboration. A major objective of this conference was to effectively communicate research results, in order to ensure that current thinking reflects sound science of radiation biology. Further, this international event addressed the use and success of scientific initiatives in radiation biology for policymakers, standard-setters, and the general public.

  19. Biological investigations of the Sandia National Laboratories Sol se Mete Aerial Cable Facility

    SciTech Connect (OSTI)

    Sullivan, R.M.

    1994-10-01

    This report provides results of a comprehensive biological field survey performed on the Sandia National Laboratories Aerial Cable Facility, at the east end of Kirtland Air Force Base (KAFB), Bernalillo County, New Mexico. This survey was conducted late September through October, 1991. ACF occupies a 440-acre tract of land withdrawn by the US Forest Service (USFS) for use by KAFB, and in turn placed under operational control of SNL by the Department of Energy (DOE). All land used by SNL for ACF is part of a 15,851-acre tract of land withdrawn by the US Forest Service. In addition, a number of different organizations use the 15,851-acre area. The project area used by SNL encompasses portions of approximately six sections (3,840 acres) of US Forest Service land located within the foothills of the west side of the Manzano Mountains (East Mesa). The biological study area is used by the KAFB, the US Department of Interior, and SNL. This area includes: (1) Sol se Mete Springs and Canyon, (2) East Anchor Access Road, (3) East Anchor Site, (4) Rocket Sled Track, (5) North Arena, (6) East Instrumentation Site and Access Road, (7) West Anchor Access Road, (8) West Anchor Site, (9) South Arena, (10) Winch Sites, (11) West Instrumentation Sites, (12) Explosive Assembly Building, (13) Control Building, (14) Lurance Canyon Road and vicinity. Although portions of approximately 960 acres of withdrawn US Forest Service land have been altered, only 700 acres have been disturbed by activities associated with ACF; approximately 2,880 acres consist of natural habitat. Absence of grazing by livestock and possibly native ungulates, and relative lack of human disturbance have allowed this area to remain in a more natural vegetative state relative to the condition of private range lands throughout New Mexico. This report evaluates threatened and endangered species found on ACF, as well as a comprehensive assessment of biological habitats.

  20. Exposure assessment: Serum levels of TCDD in Seveso, Italy

    SciTech Connect (OSTI)

    Needham, L.L.; Patterson, D.G. Jr.; Smith, S.J.; Sampson, E.J.; Gerthoux, P.M.; Brambilla, P.; Mocarelli, P.

    1999-02-01

    Accurate exposure assessment is an important step in both risk assessment and epidemiologic studies involving potential human exposure to environmental toxicants. Various methods have been used to assess human exposure. These methods include models based on one`s temporal and spatial nearness to the source, environmental levels of toxicant, and biological measures. The authors believe that the latter measure is the ``gold standard.`` In this article they present the serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels in residents of the contaminated zones in Seveso, Italy, in 1976, and delineate these data by age and gender. Some of these serum levels are among the highest ever reported and thus this population serves as a benchmark for comparison of human exposure and potential adverse health effects. One such potential population is that population consuming potentially contaminated fish.

  1. First annual report on the Biological Monitoring and Abatement Program at Oak Ridge National Laboratory

    SciTech Connect (OSTI)

    Loar, J.M.; Adams, S.M.; Blaylock, B.G.; Boston, H.L.; Frank, M.L.; Garten, C.T.; Houston, M.A.; Kimmel, B.L.; Ryon, M.G.; Smith, J.G.; Southworth, G.R.; Stewart, A.J.; Walton, B.T.; Berry, J.B.; Talmage, S.S. ); Amano, H. ); Jimenez, B.D. ); Kitchings, J.T.

    1992-08-01

    As a condition of the National Pollutant Discharge Elimination System (NPDES) permit issued to Oak Ridge National Laboratory (ORNL) on April 1, 1986, a Biological Monitoring and Abatement Program (BMAP) was developed for White Oak Creek (WOC); selected tributaries of WOC, including Fifth Creek, First Creek, Melton Branch, and Northwest Tributary; and the Clinch River. BMAP consists of seven major tasks that address both radiological and nonradiological contaminants in the aquatic and terrestrial environs on-site and the aquatic environs off-site. These tasks are (1) toxicity monitoring; (2) bioaccumulation monitoring of nonradiological contaminants in aquatic biota; (3) biological indicator studies; (4) instream ecological monitoring; (5) assessment of contaminants in the terrestrial environment; (6) radioecology of WOC and White Oak Lake (WOL); and (7) contaminant transport, distribution, and fate in the WOC embayment-Clinch River-Watts Bar Reservoir system. This document, the first of a series of annual reports presenting the results of BMAP, describes studies that were conducted from March through December 1986.

  2. Report on the biological monitoring program at Paducah Gaseous Diffusion Plant December 1990 to November 1992

    SciTech Connect (OSTI)

    Kszos, L.A.

    1994-03-01

    On September 23, 1987, the Commonwealth of Kentucky Natural Resources and Environmental Protection Cabinet issued an Agreed Order that required the development of a Biological Monitoring Program (BMP) for the Paducah Gaseous Diffusion Plant (PGDP). Beginning in fall 1991, the Environmental Sciences Division (ESD) at Oak Ridge National Lab (ORNL) added data collection and report preparation to its responsibilities for the PGDP BMP. The BMP has been continued because it has proven to be extremely valuable in identifying those effluents with the potential for adversely affecting instream fauna, assessing the ecological health of receiving streams, guiding plans for remediation, and protecting human health. In September 1992, a renewed permit was issued which requires toxicity monitoring of continuous and intermittent outfalls on a quarterly basis. The BMP for PGDP consists of three major tasks: (1) effluent and ambient toxicity monitoring, (2) bioaccumulation studies, and (3) ecological surveys of stream communities. This report includes ESD/ORNL activities occurring from December 1990 to November 1992.

  3. Physical and Computational Modeling for Chemical and Biological Weapons Airflow Applications

    SciTech Connect (OSTI)

    McEligot, Donald Marinus; Mc Creery, Glenn Ernest; Pink, Robert John; Barringer, C.; Knight, K. J.

    2002-11-01

    There is a need for information on dispersion and infiltration of chemical and biological agents in complex building environments. A recent collaborative study conducted at the Idaho National Engineering and Environmental Laboratory (INEEL) and Bechtel Corporation Research and Development had the objective of assessing computational fluid dynamics (CFD) models for simulation of flow around complicated buildings through a comparison of experimental and numerical results. The test facility used in the experiments was INEEL’s unique large Matched-Index-of-Refraction (MIR) flow system. The CFD code used for modeling was Fluent, a widely available commercial flow simulation package. For the experiment, a building plan was selected to approximately represent an existing facility. It was found that predicted velocity profiles from above the building and in front of the building were in good agreement with the measurements.

  4. Investigation and field testing of anaerobic biological treatment of pharmaceutical wastewaters

    SciTech Connect (OSTI)

    Not Available

    1990-03-30

    A study has been conducted that investigated and demonstrated the anaerobic biological treatment of wastewaters generated by the pharmaceuticals industry. This report presents the results of the multi-phase program and the conclusions and recommendations which have been derived from an analysis of the experimental data. The program was initiated in October 1985 and was conducted over a period of 26 months, at which point the experimental portions of the study were completed in December 1987. These can be divided to essentially three major tasks: screening assays to assess anaerobic treatability; bench-scale treatability investigations of the Merck Stonewall Plant wastewaters; and, pilot scale demonstration of anaerobic treatment. Each major element is discussed separately, addressing the design of the program (facilities), the experimental procedures, and finally the results of each task. The final section discusses the application of the technology to the pharmaceutical industry and the economic components associated with it. 2 refs., 54 figs., 35 tabs.

  5. Decontamination of biological warfare agents by a microwave plasma torch

    SciTech Connect (OSTI)

    Lai, Wilson; Lai, Henry; Kuo, Spencer P.; Tarasenko, Olga; Levon, Kalle

    2005-02-01

    A portable arc-seeded microwave plasma torch running stably with airflow is described and applied for the decontamination of biological warfare agents. Emission spectroscopy of the plasma torch indicated that this torch produced an abundance of reactive atomic oxygen that could effectively oxidize biological agents. Bacillus cereus was chosen as a simulant of Bacillus anthracis spores for biological agent in the decontamination experiments. Decontamination was performed with the airflow rate of 0.393 l/s, corresponding to a maximum concentration of atomic oxygen produced by the torch. The experimental results showed that all spores were killed in less than 8 s at 3 cm distance, 12 s at 4 cm distance, and 16 s at 5 cm distance away from the nozzle of the torch.

  6. Formulations for neutralization of chemical and biological toxants

    DOE Patents [OSTI]

    Tadros, Maher E.; Tucker, Mark D.

    2003-05-20

    A formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents. The formulation of the present invention non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The at least one reactive compound can be an oxidizing compound, a nucleophilic compound or a mixture of both. The formulation can kill up to 99.99999% of bacterial spores within one hour of exposure.

  7. Enhanced formulations for neutralization of chemical, biological and industrial toxants

    DOE Patents [OSTI]

    Tucker, Mark D. [Albuqueque, NM

    2008-06-24

    An enhanced formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The enhanced formulation according to the present invention is non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a bleaching activator and water.

  8. Method and apparatus for determining nutrient stimulation of biological processes

    DOE Patents [OSTI]

    Colwell, Frederick S.; Geesey, Gill G.; Gillis, Richard J.; Lehman, R. Michael

    1999-01-01

    A method and apparatus for determining the nutrients to stimulate microorganisms in a particular environment. A representative sample of microorganisms from a particular environment are contacted with multiple support means wherein each support means has intimately associated with the surface of the support means a different nutrient composition for said microorganisms in said sample. The multiple support means is allowed to remain in contact with the microorganisms in the sample for a time period sufficient to measure difference in microorganism effects for the multiple support means. Microorganism effects for the multiple support means are then measured and compared. The invention is particularly adaptable to being conducted in situ. The additional steps of regulating nutrients added to the particular environment of microorganisms can enhance the desired results. Biological systems particularly suitable for this invention are bioremediation, biologically enhanced oil recovery, biological leaching of metals, and agricultural bioprocesses.

  9. Method and apparatus for determining nutrient stimulation of biological processes

    DOE Patents [OSTI]

    Colwell, Frederick S.; Geesey, Gill G.; Gillis, Richard J.; Lehman, R. Michael

    1997-01-01

    A method and apparatus for determining the nutrients to stimulate microorganisms in a particular environment. A representative sample of microorganisms from a particular environment are contacted with multiple support means wherein each support means has intimately associated with the surface of the support means a different nutrient composition for said microorganisms in said sample. The multiple support means is allowed to remain in contact with the microorganisms in the sample for a time period sufficient to measure differences in microorganism effects for the multiple support means. Microorganism effects for the multiple support means are then measured and compared. The invention is particularly adaptable to being conducted in situ. The additional steps of regulating nutrients added to the particular environment of microorganisms can enhance the desired results. Biological systems particularly suitable for this invention are bioremediation, biologically enhanced oil recovery, biological leaching of metals, and agricultural bioprocesses.

  10. Method and apparatus for determining nutrient stimulation of biological processes

    DOE Patents [OSTI]

    Colwell, F.S.; Geesey, G.G.; Gillis, R.J.; Lehman, R.M.

    1997-11-11

    A method and apparatus is described for determining the nutrients to stimulate microorganisms in a particular environment. A representative sample of microorganisms from a particular environment are contacted with multiple support means wherein each support means has intimately associated with the surface of the support means a different nutrient composition for said microorganisms in said sample. The multiple support means is allowed to remain in contact with the microorganisms in the sample for a time period sufficient to measure differences in microorganism effects for the multiple support means. Microorganism effects for the multiple support means are then measured and compared. The invention is particularly adaptable to being conducted in situ. The additional steps of regulating nutrients added to the particular environment of microorganisms can enhance the desired results. Biological systems particularly suitable for this invention are bioremediation, biologically enhanced oil recovery, biological leaching of metals, and agricultural bioprocesses. 5 figs.

  11. Method and apparatus for determining nutrient stimulation of biological processes

    DOE Patents [OSTI]

    Colwell, F.S.; Geesey, G.G.; Gillis, R.J.; Lehman, R.M.

    1999-07-13

    A method and apparatus are disclosed for determining the nutrients to stimulate microorganisms in a particular environment. A representative sample of microorganisms from a particular environment are contacted with multiple support means wherein each support means has intimately associated with the surface of the support means a different nutrient composition for microorganisms in the sample. The multiple support means is allowed to remain in contact with the microorganisms in the sample for a time period sufficient to measure difference in microorganism effects for the multiple support means. Microorganism effects for the multiple support means are then measured and compared. The invention is particularly adaptable to being conducted in situ. The additional steps of regulating nutrients added to the particular environment of microorganisms can enhance the desired results. Biological systems particularly suitable for this invention are bioremediation, biologically enhanced oil recovery, biological leaching of metals, and agricultural bioprocesses. 5 figs.

  12. Renewable Energy from Synthetic Biology (LBNL Science at the Theater)

    ScienceCinema (OSTI)

    Keasling, Jay

    2011-04-28

    Jay Keasling, co-leader of Berkeley Lab's Helios Project, is a groundbreaking researcher in the new scientific field of synthetic biology. In Helios, he directs the biology program, incorporating a range of approaches to increasing the efficacy and economy of plants and cellulose-degrading microbes to make solar-based fuels. He is a UC Berkeley professor of Chemical and Bioengineering, and founder of Amyris Biotechnologies, a company that was honored as a Technology Pioneer for 2006 by the World Economic Forum. Keasling has succeeded in using synthetic biology to develop a yeast-based production scheme for precursors of the antimalarial drug artemisinin in work funded by the Bill & Melinda Gates Foundation.

  13. Chemical and biological nonproliferation program. FY99 annual report

    SciTech Connect (OSTI)

    2000-03-01

    This document is the first of what will become an annual report documenting the progress made by the Chemical and Biological Nonproliferation Program (CBNP). It is intended to be a summary of the program's activities that will be of interest to both policy and technical audiences. This report and the annual CBNP Summer Review Meeting are important vehicles for communication with the broader chemical and biological defense and nonproliferation communities. The Chemical and Biological Nonproliferation Program Strategic Plan is also available and provides additional detail on the program's context and goals. The body of the report consists of an overview of the program's philosophy, goals and recent progress in the major program areas. In addition, an appendix is provided with more detailed project summaries that will be of interest to the technical community.

  14. Semiconductor Quantum Rods as Single Molecule FluorescentBiological Labels

    SciTech Connect (OSTI)

    Fu, Aihua; Gu, Weiwei; Boussert, Benjamine; Koski, Kristie; Gerion, Daniele; Manna, Liberato; Le Gros, Mark; Larabell, Carolyn; Alivisatos, A. Paul

    2006-05-29

    In recent years, semiconductor quantum dots have beenapplied with great advantage in a wide range of biological imagingapplications. The continuing developments in the synthesis of nanoscalematerials and specifically in the area of colloidal semiconductornanocrystals have created an opportunity to generate a next generation ofbiological labels with complementary or in some cases enhanced propertiescompared to colloidal quantum dots. In this paper, we report thedevelopment of rod shaped semiconductor nanocrystals (quantum rods) asnew fluorescent biological labels. We have engineered biocompatiblequantum rods by surface silanization and have applied them fornon-specific cell tracking as well as specific cellular targeting. Theproperties of quantum rods as demonstrated here are enhanced sensitivityand greater resistance for degradation as compared to quantum dots.Quantum rods have many potential applications as biological labels insituations where their properties offer advantages over quantumdots.

  15. SCADA Vulnerability Assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Vulnerability Assessments - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs

  16. Venetie, Alaska energy assessment.

    SciTech Connect (OSTI)

    Jensen, Richard Pearson; Baca, Micheal J.; Schenkman, Benjamin L.; Brainard, James Robert

    2013-07-01

    This report summarizes the Energy Assessment performed for Venetie, Alaska using the principals of an Energy Surety Microgrid (ESM) The report covers a brief overview of the principals of ESM, a site characterization of Venetie, a review of the consequence modeling, some preliminary recommendations, and a basic cost analysis.

  17. Technology Readiness Assessment Guide

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2011-09-15

    This document was developed to assist individuals and teams that will be involved in conducting Technology Readiness Assessments (TRAs) and developing Technology Maturation Plans (TMPs) for the Department of Energy (DOE) capital acquisition assets subjects to DOE O 413.3B.

  18. PRELIMINARY ASSESSMENT TEMPLATE

    Broader source: Energy.gov [DOE]

    Document presents a template for the preliminary assessment (PA) that energy service companies (ESCOs) are required to conduct in an energy savings performance contract (ESPC) project under the U.S.Department of Energy's indefinite-delivery, indefinite-quantity ESPC contract.

  19. Condition Assessment Information System

    Energy Science and Technology Software Center (OSTI)

    2002-09-16

    CAIS2000 records, tracks and cost maintenance deficiencies associated with condition assessments of real property assets. Cost information is available for 39,000 items in the currenht RS Means, Facilities Construction Manual. These costs can, in turn, be rolled by by asset to produce the summary condition of an asset or site.

  20. Ultrasonic pipe assessment

    DOE Patents [OSTI]

    Thomas, Graham H.; Morrow, Valerie L.; Levie, Harold; Kane, Ronald J.; Brown, Albert E.

    2003-12-23

    An ultrasonic pipe or other structure assessment system includes an ultrasonic transducer positioned proximate the pipe or other structure. A fluid connection between the ultrasonic transducer and the pipe or other structure is produced. The ultrasonic transducer is moved relative to the pipe or other structure.

  1. Invited Review Article: Advanced light microscopy for biological space research

    SciTech Connect (OSTI)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; Loon, Jack J. W. A. van

    2014-10-15

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  2. Industrial Energy Efficiency Assessments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Industrial Energy Efficiency Assessments Industrial Energy Efficiency Assessments Details about the Industrial Energy Efficiency Assessments program and its implementation in ...

  3. Industrial Energy Efficiency Assessments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Industrial Energy Efficiency Assessments Industrial Energy Efficiency Assessments Details about the Industrial Energy Efficiency Assessments program and its implementation in...

  4. Community Readiness Assessments | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Readiness Assessments Community Readiness Assessments Better Buildings Residential Network Program Sustainability Peer Exchange Call Series: Community Readiness Assessments, Call ...

  5. Concentrated formulations and methods for neutralizing chemical and biological toxants

    SciTech Connect (OSTI)

    Tucker, Mark D.; Betty, Rita G.; Tadros, Maher E.

    2004-04-20

    A formulation and method of making and using that neutralizes the adverse health effects of both chemical and biological toxants, especially chemical warfare (CW) and biological warfare (BW) agents. The aqueous formulation is non-toxic and non-corrosive and can be delivered as a long-lasting foam, spray, or fog. The formulation includes solubilizing compounds that serve to effectively render the CW or BW toxant susceptible to attack, so that a nucleophillic agent can attack the compound via a hydrolysis or oxidation reaction. The formulation can kill up to 99.99999% of bacterial spores within one hour of exposure.

  6. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Biological Imaging by Soft X-Ray Diffraction Microscopy Print Wednesday, 30 November 2005 00:00 Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes

  7. Computational Proteomics: High-throughput Analysis for Systems Biology

    SciTech Connect (OSTI)

    Cannon, William R.; Webb-Robertson, Bobbie-Jo M.

    2007-01-03

    High-throughput (HTP) proteomics is a rapidly developing field that offers the global profiling of proteins from a biological system. The HTP technological advances are fueling a revolution in biology, enabling analyses at the scales of entire systems (e.g., whole cells, tumors, or environmental communities). However, simply identifying the proteins in a cell is insufficient for understanding the underlying complexity and operating mechanisms of the overall system. Systems level investigations are relying more and more on computational analyses, especially in the field of proteomics generating large-scale global data.

  8. COLLOQUIUM: Plasma Mediated Effects on Biological Cells | Princeton Plasma

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Lab October 8, 2014, 4:00pm to 5:30pm Colloquia MBG Auditorium COLLOQUIUM: Plasma Mediated Effects on Biological Cells Professor Mounir Laroussi Old Dominion University Low temperature plasma (LTP) in air-containing gas mixtures produce reactive oxygen species (ROS) such as O, O2-, and OH and reactive nitrogen species (RNS) such as NO and NO2 which exhibit strong oxidative properties and/or trigger signaling pathways in biological cells. For example oxidation of the lipids and

  9. Detection and differentiation of coxiella burnetii in biological fluids

    DOE Patents [OSTI]

    Frazier, Marvin E.; Mallavia, Louis P.; Samuel, James E.; Baca, Oswald G.

    1990-01-01

    Methods for detecting the presence of Coxiella burenetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA (specifically rickettsial DNA) with a C. burnetii-specific labeled DNA probe. Radioisotope and biotin labels are preferred, allowing detection through autoradiography and colorimetric assays, respectively.

  10. Detection and differentiation of coxiella burnetii in biological fluids

    DOE Patents [OSTI]

    Frazier, Marvin E.; Mallavia, Louis P.; Samuel, James E.; Baca, Oswald G.

    1993-01-01

    Methods for detecting the presence of Coxiella burnetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA with a DNA probe containing DNA sequences that specifically hybridize with C. burnetii DNA of strains associated with the capacity to cause acute or chronic disease.

  11. Detection and differentiation of coxiella burnetii in biological fluids

    DOE Patents [OSTI]

    Frazier, Marvin E.; Mallavia, Louis P.; Baca, Oswald G.; Samuel, James E.

    1989-01-01

    Methods for detecting the presence of Coxiella burnetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA (specifically rickettsial DNA) with a C. burnetii-specific labeled DNA probe. Radioisotope and biotin labels are preferred, allowing detection through autoradiography and colorimetric assays, respectively.

  12. UAIEE and Industrial Assessment Centers

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    55-62011| Industrial Assessment Centers * Started in 1976 * Currently 26 Centers across the US * Almost...

  13. Oak Ridge Reservation Needs Assessment

    Broader source: Energy.gov [DOE]

    Needs Assessment for former Oak Ridge National Laboratory and Y-12 Nuclear Security Complex production workers.

  14. EA-1391: Final Environmental Assessment

    Broader source: Energy.gov [DOE]

    Environmental Assessment for Presidential Permit Applications for Baja California, Inc. and Sempra Energy Resources

  15. EA-1207: Final Environmental Assessment

    Broader source: Energy.gov [DOE]

    Pit Disassembly and Conversion Demonstration Environmental Assessment and Research and Development Activities

  16. Biological Systems Science Division (BSSD) | U.S. DOE Office of Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (SC) Biological Systems Science Division (BSSD) Biological and Environmental Research (BER) BER Home About Research Biological Systems Science Division (BSSD) Genomic Science DOE Bioenergy Research Centers Bioimaging Technology DOE Joint Genome Institute Structural Biology Radiochemistry & Imaging Instrumentation Radiobiology: Low Dose Radiation Research DOE Human Subjects Protection Program Climate and Environmental Sciences Division (CESD) Research Abstracts Searchable Archive of BER

  17. Biological optimization systems for enhancing photosynthetic efficiency and methods of use

    DOE Patents [OSTI]

    Hunt, Ryan W; Chinnasamy, Senthil; Das, Keshav C; Rolim de Mattos, Erico

    2014-02-25

    The present disclosure relates to biological optimization systems for enhancing photosynthetic efficiency and methods of use.

  18. MODEL-BASED HYDROACOUSTIC BLOCKAGE ASSESSMENT AND DEVELOPMENT OF AN EXPLOSIVE SOURCE DATABASE

    SciTech Connect (OSTI)

    Matzel, E; Ramirez, A; Harben, P

    2005-07-11

    We are continuing the development of the Hydroacoustic Blockage Assessment Tool (HABAT) which is designed for use by analysts to predict which hydroacoustic monitoring stations can be used in discrimination analysis for any particular event. The research involves two approaches (1) model-based assessment of blockage, and (2) ground-truth data-based assessment of blockage. The tool presents the analyst with a map of the world, and plots raypath blockages from stations to sources. The analyst inputs source locations and blockage criteria, and the tool returns a list of blockage status from all source locations to all hydroacoustic stations. We are currently using the tool in an assessment of blockage criteria for simple direct-path arrivals. Hydroacoustic data, predominantly from earthquake sources, are read in and assessed for blockage at all available stations. Several measures are taken. First, can the event be observed at a station above background noise? Second, can we establish backazimuth from the station to the source. Third, how large is the decibel drop at one station relative to other stations. These observational results are then compared with model estimates to identify the best set of blockage criteria and used to create a set of blockage maps for each station. The model-based estimates are currently limited by the coarse bathymetry of existing databases and by the limitations inherent in the raytrace method. In collaboration with BBN Inc., the Hydroacoustic Coverage Assessment Model (HydroCAM) that generates the blockage files that serve as input to HABAT, is being extended to include high-resolution bathymetry databases in key areas that increase model-based blockage assessment reliability. An important aspect of this capability is to eventually include reflected T-phases where they reliably occur and to identify the associated reflectors. To assess how well any given hydroacoustic discriminant works in separating earthquake and in-water explosion populations it is necessary to have both a database of reference earthquake events and of reference in-water explosive events. Although reference earthquake events are readily available, explosive reference events are not. Consequently, building an in-water explosion reference database requires the compilation of events from many sources spanning a long period of time. We have developed a database of small implosive and explosive reference events from the 2003 Indian Ocean Cruise data. These events were recorded at some or all of the IMS Indian Ocean hydroacoustic stations: Diego Garcia, Cape Leeuwin, and Crozet Island. We have also reviewed many historical large in-water explosions and identified five that have adequate source information and can be positively associated to the hydrophone recordings. The five events are: Cannekin, Longshot, CHASE-3, CHASE-5, and IITRI-1. Of these, the first two are nuclear tests on land but near water. The latter three are in-water conventional explosive events with yields from ten to hundreds of tons TNT equivalent. The objective of this research is to enhance discrimination capabilities for events located in the world's oceans. Two research and development efforts are needed to achieve this: (1) improvement in discrimination algorithms and their joint statistical application to events, and (2) development of an automated and accurate blockage prediction capability that will identify all stations and phases (direct and reflected) from a given event that will have adequate signal to be used in a discrimination analysis. The strategy for improving blockage prediction in the world's oceans is to improve model-based prediction of blockage and to develop a ground-truth database of reference events to assess blockage. Currently, research is focused on the development of a blockage assessment software tool. The tool is envisioned to develop into a sophisticated and unifying package that optimally and automatically assesses both model and data based blockage predictions in all ocean basins, for all NDC stations, and accounting for reflected phases (Pulli et al., 2000). Currently, we have focused our efforts on the Diego Garcia, Cape Leeuwin and Crozet Island hydroacoustic stations in the Indian Ocean.

  19. Development of nonproliferation and assessment scenarios.

    SciTech Connect (OSTI)

    Finley, Melissa; Barnett, Natalie Beth

    2005-10-01

    The overall objective of the Nonproliferation and Assessments Scenario Development project is to create and analyze potential and plausible scenarios that would lead to an adversary's ability to acquire and use a biological weapon. The initial three months of funding was intended to be used to develop a scenario to demonstrate the efficacy of this analysis methodology; however, it was determined that a substantial amount of preliminary data collection would be needed before a proof of concept scenario could be developed. We have dedicated substantial effort to determine the acquisition pathways for Foot and Mouth Disease Virus, and similar processes will be applied to all pathogens of interest. We have developed a biosecurity assessments database to capture information on adversary skill locales, available skill sets in specific regions, pathogen sources and regulations involved in pathogen acquisition from legitimate facilities. FY06 funding, once released, will be dedicated to data collection on acquisition, production and dissemination requirements on a pathogen basis. Once pathogen data has been collected, scenarios will be developed and scored.

  20. EA-2011: Final Environmental Assessment

    Broader source: Energy.gov [DOE]

    Proposed Release of Three Parasitoids for the Biological Control of the Emerald Ash Borer (Agrilus Planipennis) in the Continental United States The DOE Oak Ridge Office reviewed and adopted a July 2007 EA prepared by the USDA Animal and Plant Health Inspection Service that analyzed the potential environmental impacts of the release of three parasitoids into the continental U.S. for the biological control of the emerald ash borer, a nonnative invasive beetle.

  1. Behavior of REE in geological and biological systems

    SciTech Connect (OSTI)

    Laul, J.C.; Weimer, W.C.

    1981-05-01

    The REE abundances when normalized to primordial (chondritic) abundances behave as a smooth function of the REE ionic radii in both the geological and biological systems. The REE are hardly fractionated chemically through various stages of their transformation from soil-soil extract-plant-geological systems.

  2. Thin film composition with biological substance and method of making

    SciTech Connect (OSTI)

    Campbell, A.A.; Song, L.

    1999-09-28

    The invention provides a thin-film composition comprising an underlying substrate of a first material including a plurality of attachment sites; a plurality of functional groups chemically attached to the attachment sites of the underlying substrate; and a thin film of a second material deposited onto the attachment sites of the underlying substrate, and a biologically active substance deposited with the thin-film. Preferably the functional groups are attached to a self assembling monolayer attached to the underlying substrate. Preferred functional groups attached to the underlying substrate are chosen from the group consisting of carboxylates, sulfonates, phosphates, optionally substituted, linear or cyclo, alkyl, alkene, alkyne, aryl, alkylaryl, amine, hydroxyl, thiol, silyl, phosphoryl, cyano, metallocenyl, carbonyl, and polyphosphate. Preferred materials for the underlying substrate are selected from the group consisting of a metal, a metal alloy, a plastic, a polymer, a proteic film, a membrane, a glass or a ceramic. The second material is selected from the group consisting of inorganic crystalline structures, inorganic amorphous structures, organic crystalline structures, and organic amorphous structures. Preferred second materials are phosphates, especially calcium phosphates and most particularly calcium apatite. The biologically active molecule is a protein, peptide, DNA segment, RNA segment, nucleotide, polynucleotide, nucleoside, antibiotic, antimicrobial, radioisotope, chelated radioisotope, chelated metal, metal salt, anti-inflammatory, steroid, nonsteroid anti-inflammatory, analgesic, antihistamine, receptor binding agent, or chemotherapeutic agent, or other biologically active material. Preferably the biologically active molecule is an osteogenic factor consisting of the compositions listed above.

  3. Computational approaches to discovering semantics in molecular biology

    SciTech Connect (OSTI)

    Lipton, R.J. ); Marr, T.G. . Theoretical Div.); Welsh, J.D. . Dept. of Biology)

    1989-07-01

    One of the central questions of molecular biology is the discovery of the semantics of DNA. This discovery relies in a critical way on a variety of expensive computations. In order to solve these computations, both parallel computers and special-purpose hardware play a major role.

  4. Thin film composition with biological substance and method of making

    DOE Patents [OSTI]

    Campbell, Allison A.; Song, Lin

    1999-01-01

    The invention provides a thin-film composition comprising an underlying substrate of a first material including a plurality of attachment sites; a plurality of functional groups chemically attached to the attachment sites of the underlying substrate; and a thin film of a second material deposited onto the attachment sites of the underlying substrate, and a biologically active substance deposited with the thin-film. Preferably the functional groups are attached to a self assembling monolayer attached to the underlying substrate. Preferred functional groups attached to the underlying substrate are chosen from the group consisting of carboxylates, sulfonates, phosphates, optionally substituted, linear or cyclo, alkyl, alkene, alkyne, aryl, alkylaryl, amine, hydroxyl, thiol, silyl, phosphoryl, cyano, metallocenyl, carbonyl, and polyphosphate. Preferred materials for the underlying substrate are selected from the group consisting of a metal, a metal alloy, a plastic, a polymer, a proteic film, a membrane, a glass or a ceramic. The second material is selected from the group consisting of inorganic crystalline structures, inorganic amorphus structures, organic crystalline structures, and organic amorphus structures. Preferred second materials are phosphates, especially calcium phosphates and most particularly calcium apatite. The biologically active molecule is a protein, peptide, DNA segment, RNA segment, nucleotide, polynucleotide, nucleoside, antibiotic, antimicrobal, radioisotope, chelated radioisotope, chelated metal, metal salt, anti-inflamatory, steriod, nonsteriod anti-inflammatory, analgesic, antihistamine, receptor binding agent, or chemotherapeutic agent, or other biologically active material. Preferably the biologically active molecule is an osteogenic factor the compositions listed above.

  5. Biological Conversion of Sugars to Hydrocarbons Technology Pathway

    Broader source: Energy.gov [DOE]

    This technology pathway case investigates the biological conversion of biomass-derived sugars to hydrocarbon biofuels, utilizing data from recent literature references and information consistent with recent pilot-scale demonstrations at NREL. Technical barriers and key research needs have been identified that should be pursued for the pathway to become competitive with petroleum-derived gasoline-, diesel-, and jet-range hydrocarbon blendstocks.

  6. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    SciTech Connect (OSTI)

    Oldenburg, Curtis; Oldenburg, Curtis M.; Torn, Margaret S.

    2008-03-21

    Fossil fuel combustion, deforestation, and biomass burning are the dominant contributors to increasing atmospheric carbon dioxide (CO{sub 2}) concentrations and global warming. Many approaches to mitigating CO{sub 2} emissions are being pursued, and among the most promising are terrestrial and geologic carbon sequestration. Recent advances in ecology and microbial biology offer promising new possibilities for enhancing terrestrial and geologic carbon sequestration. A workshop was held October 29, 2007, at Lawrence Berkeley National Laboratory (LBNL) on Biologically Enhanced Carbon Sequestration (BECS). The workshop participants (approximately 30 scientists from California, Illinois, Oregon, Montana, and New Mexico) developed a prioritized list of research needed to make progress in the development of biological enhancements to improve terrestrial and geologic carbon sequestration. The workshop participants also identified a number of areas of supporting science that are critical to making progress in the fundamental research areas. The purpose of this position paper is to summarize and elaborate upon the findings of the workshop. The paper considers terrestrial and geologic carbon sequestration separately. First, we present a summary in outline form of the research roadmaps for terrestrial and geologic BECS. This outline is elaborated upon in the narrative sections that follow. The narrative sections start with the focused research priorities in each area followed by critical supporting science for biological enhancements as prioritized during the workshop. Finally, Table 1 summarizes the potential significance or 'materiality' of advances in these areas for reducing net greenhouse gas emissions.

  7. Physics in medicine and biology encyclopedia 2-volume set

    SciTech Connect (OSTI)

    McAinsh, T.F.

    1986-01-01

    The Physics in Medicine and Biology Encyclopedia provides in two volumes a review of a wide range of topics of current interest in medical physics, bioengineering and biophysics. The Encyclopedia is extensively cross-referenced, indexed and illustrated, and all articles are complete with fully verified bibliographies. A glossary gives full details of specialized terms appearing in the Encyclopedia.

  8. Bio Risk Assessment Tool

    Energy Science and Technology Software Center (OSTI)

    2004-07-22

    The Biosecurity Risk Assessment Tool (BRAT) is a new type of computer application for the screening-level assessment of risk to dairy operations. BRAT for Dairies is designed to be intuitive and easy to use. Users enter basic data-property address, feed management, employee population, and so on - into the interface. Using these data and rules found in an expert system. BRAT for Dairies consults appropriate sections of its database. The expert system determines the riskmore » implications of the basic data, e.g. diseases are closely tied to pen location with respect to the outside world, When the analysis is complete, BRAT for Dairies evaluates and allocates the risk for each hazard, ranks the risks, and displays the results graphically.« less

  9. Risk Identification and Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Risk Identification and Assessment [Sections in brackets are for instructions; these should be deleted or replaced with specifics in the template.] Subsystem Title or Section within Subsystem [In the first column, using short bullets, fill in "what can go wrong," or a brief description of a potential benefit from a program or action. Add additional rows as necessary. Fill in the other columns using the rating guidelines in the attached reference pages.] |Risk|Probability|Impact|Risk

  10. Technology Readiness Assessment Report

    Office of Environmental Management (EM)

    Technology Readiness Assessment Report March 2010 U U . . S S . . D D e e p p a a r r t t m m e e n n t t o o f f E E n n e e r r g g y y O O f f f f i i c c e e o o f f E E n n v ...

  11. Probabilistic Risk Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Risk Assessment - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs Advanced Nuclear

  12. Risk and Safety Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Safety Assessment - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs Advanced

  13. Facility Environmental Vulnerability Assessment

    SciTech Connect (OSTI)

    Van Hoesen, S.D.

    2001-07-09

    From mid-April through the end of June 2001, a Facility Environmental Vulnerability Assessment (FEVA) was performed at Oak Ridge National Laboratory (ORNL). The primary goal of this FEVA was to establish an environmental vulnerability baseline at ORNL that could be used to support the Laboratory planning process and place environmental vulnerabilities in perspective. The information developed during the FEVA was intended to provide the basis for management to initiate immediate, near-term, and long-term actions to respond to the identified vulnerabilities. It was expected that further evaluation of the vulnerabilities identified during the FEVA could be carried out to support a more quantitative characterization of the sources, evaluation of contaminant pathways, and definition of risks. The FEVA was modeled after the Battelle-supported response to the problems identified at the High Flux Beam Reactor at Brookhaven National Laboratory. This FEVA report satisfies Corrective Action 3A1 contained in the Corrective Action Plan in Response to Independent Review of the High Flux Isotope Reactor Tritium Leak at the Oak Ridge National Laboratory, submitted to the Department of Energy (DOE) ORNL Site Office Manager on April 16, 2001. This assessment successfully achieved its primary goal as defined by Laboratory management. The assessment team was able to develop information about sources and pathway analyses although the following factors impacted the team's ability to provide additional quantitative information: the complexity and scope of the facilities, infrastructure, and programs; the significantly degraded physical condition of the facilities and infrastructure; the large number of known environmental vulnerabilities; the scope of legacy contamination issues [not currently addressed in the Environmental Management (EM) Program]; the lack of facility process and environmental pathway analysis performed by the accountable line management or facility owner; and poor facility and infrastructure drawings. The assessment team believes that the information, experience, and insight gained through FEVA will help in the planning and prioritization of ongoing efforts to resolve environmental vulnerabilities at UT-Battelle--managed ORNL facilities.

  14. Bridge Condition Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Condition and Performance Assessment Background How bridges respond to extreme loading conditions, such as during high winds and severe storms, and to the effects of aging, such as corrosion- and fatigue-induced cracking, is a major concern for the Federal Highway Administration (FHWA). The FHWA is working to ensure that highway structures are safe and reliable under all service conditions, including potential structural, environmental, and human-generated threats. Role of High-Performance

  15. Photovoltaic technology assessment

    SciTech Connect (OSTI)

    Backus, C.E.

    1981-01-01

    After a brief review of the history of photovoltaic devices and a discussion of the cost goals set for photovoltaic modules, the status of photovoltaic technology is assessed. Included are discussions of: current applications, present industrial production, low-cost silicon production techniques, energy payback periods for solar cells, advanced materials research and development, concentrator systems, balance-of-system components. Also discussed are some nontechnical aspects, including foreign markets, US government program approach, and industry attitudes and approaches. (LEW)

  16. Security Risk Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Security Risk Assessment - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs Advanced

  17. Waste minimization assessment procedure

    SciTech Connect (OSTI)

    Kellythorne, L.L. )

    1993-01-01

    Perry Nuclear Power Plant began developing a waste minimization plan early in 1991. In March of 1991 the plan was documented following a similar format to that described in the EPA Waste Minimization Opportunity Assessment Manual. Initial implementation involved obtaining management's commitment to support a waste minimization effort. The primary assessment goal was to identify all hazardous waste streams and to evaluate those streams for minimization opportunities. As implementation of the plan proceeded, non-hazardous waste streams routinely generated in large volumes were also evaluated for minimization opportunities. The next step included collection of process and facility data which would be useful in helping the facility accomplish its assessment goals. This paper describes the resources that were used and which were most valuable in identifying both the hazardous and non-hazardous waste streams that existed on site. For each material identified as a waste stream, additional information regarding the materials use, manufacturer, EPA hazardous waste number and DOT hazard class was also gathered. Once waste streams were evaluated for potential source reduction, recycling, re-use, re-sale, or burning for heat recovery, with disposal as the last viable alternative.

  18. Enjebi Island dose assessment

    SciTech Connect (OSTI)

    Robison, W.L.; Conrado, C.L.; Phillips, W.A.

    1987-07-01

    We have updeated the radiological dose assessment for Enjebi Island at Enewetak Atoll using data derived from analysis of food crops grown on Enjebi. This is a much more precise assessment of potential doses to people resettling Enjebi Island than the 1980 assessment in which there were no data available from food crops on Enjebi. Details of the methods and data used to evaluate each exposure pathway are presented. The terrestrial food chain is the most significant potential exposure pathway and /sup 137/Cs is the radionuclide responsible for most of the estimated dose over the next 50 y. The doses are calculated assuming a resettlement date of 1990. The average wholebody maximum annual estimated dose equivalent derived using our diet model is 166 mremy;the effective dose equivalent is 169 mremy. The estimated 30-, 50-, and 70-y integral whole-body dose equivalents are 3.5 rem, 5.1 rem, and 6.2 rem, respectively. Bone-marrow dose equivalents are only slightly higher than the whole-body estimates in each case. The bone-surface cells (endosteal cells) receive the highest dose, but they are a less sensitive cell population and are less sensitive to fatal cancer induction than whole body and bone marrow. The effective dose equivalents for 30, 50, and 70 y are 3.6 rem, 5.3 rem, and 6.6 rem, respectively. 79 refs., 17 figs., 24 tabs

  19. Fossil plant self assessment

    SciTech Connect (OSTI)

    Bozgo, R.H.; Maguire, B.A.

    1996-07-01

    The increasingly competitive environment of the electric utility business is focusing utilities attention on reducing the cost of electricity generation. By using benchmark indicators, gains are being sought in plant material condition with corresponding improvements in operating efficiency and capacity factor as well as reductions in Operating and Maintenance (O&M) costs. In designing a process for improvement, Consolidated Edison Company of New York, Inc. (Con Edison) plant managers were asked to review and approve objectives and criteria for Fossil Plant Operations. The program methods included optimizing work processes (including material condition, maintenance programs, work control systems, and personnel performance); team building techniques to foster personnel buy-in of the process; and long term cultural change to insure an ongoing continuous improvement process with measurable results. The program begins with a self assessment of each plant based upon the approved Objectives and Criteria. The Criteria and Review Approaches (CRAs) are established by senior management and the review team. The criteria cover Management, Operations, Maintenance, and Support Functions including Technical Support, Training and Qualification, Environmental Compliance, Chemistry, and Safety and Emergency Preparedness. The Assessment is followed by a review of corrective action plans and an interim corrective action review. Annual Assessments are planned to ensure continuous improvement. Emphasis is placed on progress made in maintenance at the fossil stations.

  20. Enterprise Assessments Operational Awareness Record for the Assessment...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Site K-West Annex Facility (OAR EA-HANFORD-2015-09-09) Enterprise Assessments Operational Awareness Record for the Assessment of Construction at the Hanford Site K-West Annex ...

  1. TEPP Planning Products Model Needs Assessment Self Assessment...

    Office of Environmental Management (EM)

    Planning Products Model Needs Assessment Self Assessment Document Prepared for the Department of Energy Office of Transportation and Emergency Management 02B00215-13.p65 1 Model ...

  2. Chemical and biological warfare: Biology, chemistry, and toxicology. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect (OSTI)

    1996-10-01

    The bibliography contains citations concerning the physiological effects, physicochemical effects, and toxicology of chemical and biological warfare agents. Citations discuss toxic chemicals, chemical agent simulants, detoxification and decontamination, environmental toxicity, and land pollution. Detection techniques and warning systems are examined in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  3. Chemical and biological warfare: Biology, chemistry, and toxicology. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect (OSTI)

    1995-10-01

    The bibliography contains citations concerning the physiological effects, physicochemical effects, and toxicology of chemical and biological warfare agents. Citations discuss toxic chemicals, chemical agent simulants, detoxification and decontamination, environmental toxicity, and land pollution. Detection techniques and warning systems are examined in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  4. Chemical and biological warfare: Biology, chemistry, and toxicology. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect (OSTI)

    1995-03-01

    The bibliography contains citations concerning the physiological effects, physicochemical effects, and toxicology of chemical and biological warfare agents. Citations discuss toxic chemicals, chemical agent simulants, detoxification and decontamination, environmental toxicity, and land pollution. Detection techniques and warning systems are examined in a separate bibliography. (Contains a minimum of 229 citations and includes a subject term index and title list.)

  5. Chemical and biological warfare: Biology, chemistry, and toxicology. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect (OSTI)

    1997-11-01

    The bibliography contains citations concerning the physiological effects, physicochemical effects, and toxicology of chemical and biological warfare agents. Citations discuss toxic chemicals, chemical agent simulants, detoxification and decontamination, environmental toxicity, and land pollution. Detection techniques and warning systems are examined in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  6. Enterprise Assessments Assessment of Selected Conduct of Operations

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Processes at the Waste Isolation Pilot Plant - April 2016 | Department of Energy Selected Conduct of Operations Processes at the Waste Isolation Pilot Plant - April 2016 Enterprise Assessments Assessment of Selected Conduct of Operations Processes at the Waste Isolation Pilot Plant - April 2016 April 2016 Assessment of Selected Conduct of Operations Processes at the Waste Isolation Pilot Plant - April 2016 The U.S. Department of Energy's Office of Environment, Safety and Health Assessments,

  7. Energy Assessment Results: Most Commonly Identified Recommendations

    Broader source: Energy.gov [DOE]

    The Missouri Industrial Assessment Center shares its experience providing energy assessments to local industry.

  8. SB6.0: The 6th International meeting on Synthetic Biology, July 9-11, 2013

    SciTech Connect (OSTI)

    Kahl, Linda J.

    2015-04-23

    The Synthetic Biology conference series (SBx.0) is the preeminent academic meeting in synthetic biology. Organized by the BioBricks Foundation, the SBx.0 conference series brings together leading researchers, students, industry executives, and policy makers from around the world to share, consider, debate, and plan efforts to make biology easier to engineer. Historically held every two years, the SBx.0 conferences are held in alternating locations in the United States, Europe, and Asia to encourage global participation and collaboration so that the ramifications of synthetic biology research and development are most likely to be safe ethical, and beneficial. On 9-11 July 2013, the 6th installment of the synthetic biology conference series (SB6.0) was held on the campus of Imperial College London (http://sb6.biobricks.org). The SB6.0 conference was attended by over 700 people, and many more were able to participate via video digital conference (http://sb6.biobricks.org/digital-conference/). Over the course of three days, the SB6.0 conference agenda included plenary sessions, workshops, and poster presentations covering topics ranging from the infrastructure needs arising when “Systematic Engineering Meets Biological Complexity” and design-led considerations for “Connecting People and Technologies” to discussions on “Engineering Biology for New Materials,” “Assessing Risk and Managing Biocontainment,” and “New Directions for Energy and Sustainability.” The $10,150 grant awarded by the U.S. Department of Energy (DE-SC0010233) to the BioBricks Foundation was used to provide partial reimbursement for the travel expenses of leading researchers from the United States to speak at the SB6.0 conference. A total of $9,450 was used to reimburse U.S. speakers for actual expenses related to the SB6.0 conference, including airfare (economy or coach only), ground transportation, hotel, and registration fees. In addition, $700 of the grant was used to offset direct administrative costs associated with selecting speakers (preparing announcements, evaluating abstract submissions) and handling travel arrangements. Leading U.S. researchers selected to speak at the SB6.0 conference included: Adam Arkin, Ph.D. Division Director of the Physical Biosciences Division at the Lawrence Berkeley National Laboratory and Professor in the Department of Bioengineering at UC Berkeley Jay Keasling, Ph.D. Professor in the Department of Bioengineering at Berkeley, Senior Faculty Scientist and Associate Laboratory Director of the Lawrence Berkeley National Laboratory, and Chief Executive Officer of the Joint BioEnergy Institute. Debra Mathews, Ph.D. Assistant Director for Science Programs for the Johns Hopkins Berman Institute of Bioethics, Assistant Professor in the Department of Pediatrics, and Affiliate Faculty in the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine. Richard Murray, Ph.D. Thomas E. and Doris Everhart Professor of Control & Dynamical Systems and Bioengineering at Caltech. Sarah Richardson, Ph.D. Distinguished Postdoctoral Fellow in Genomics at the Lawrence Berkeley National Laboratory and the Department of Energy Joint Genome Institute. and others (for a complete listing of speakers presenting at the SB6.0 conference see http://sb6.biobricks.org/speakers/) The SB6.0 conference was the largest synthetic biology conference to date, and highlights of the SB6.0 conference have been published in a special issue of ACS Synthetic Biology (http://pubs.acs.org/toc/asbcd6/3/3). The BioBricks Foundation appreciates the support of the U.S. Department of Energy in helping to make this most influential and important conference in the field of synthetic biology a success.

  9. Turbine imaging technology assessment

    SciTech Connect (OSTI)

    Moursund, R. A.; Carlson, T. J.

    2004-12-01

    The goal of this project was to identify and evaluate imaging technologies for observing juvenile fish within a Kaplan turbine, and specifically that would enable scientists to determine mechanisms of fish injury within an operating turbine unit. This report documents the opportunities and constraints for observing juvenile fish at specific locations during turbine passage. These observations were used to make modifications to dam structures and operations to improve conditions for fish passage while maintaining or improving hydropower production. The physical and hydraulic environment that fish experience as they pass through the hydroelectric plants were studied and the regions with the greatest potential for injury were defined. Biological response data were also studied to determine the probable types of injuries sustained in the turbine intake and what types of injuries are detectable with imaging technologies. The study grouped injury-causing mechanisms into two categories: fluid (pressure/cavitation, shear, turbulence) and mechanical (strike/collision, grinding/pinching, scraping). The physical constraints of the environment, together with the likely types of injuries to fish, provided the parameters needed for a rigorous imaging technology evaluation. Types of technology evaluated included both tracking and imaging systems using acoustic technologies (such as sonar and acoustic tags) and optic technologies (such as pulsed-laser videography, which is high-speed videography using a laser as the flash). Criteria for determining image data quality such as frame rate, target detectability, and resolution were used to quantify the minimum requirements of an imaging sensor.

  10. Third report on the Oak Ridge K-25 Site Biological Monitoring and Abatement Program for Mitchell Branch

    SciTech Connect (OSTI)

    Hinzman, R.L.; Adams, S.M.; Ashwood, T.L.

    1995-08-01

    As a condition of the modified National Pollutant Discharge Elimination System (NPDES) permit issued to the Oak Ridge Gaseous Diffusion Plant (ORGDP; now referred to as the Oak Ridge K-25 Site) on September 11, 1986, a Biological Monitoring and Abatement Program (BMAP) was developed for the receiving stream (Mitchell Branch or K-1700 stream). On October 1, 1992, a renewed NPDES permit was issued for the K-25 Site. A biological monitoring plan was submitted for Mitchell Branch, Poplar Creek, Poplar Creek Embayment of the Clinch River and any unnamed tributaries of these streams. The objectives of BMAP are to (1) demonstrate that the effluent limitations established for the Oak Ridge K-25 Site protect and maintain the use of Mitchell Branch for growth and propagation of fish and other aquatic life and (2) document the effects on stream biota resulting from operation of major new pollution abatement facilities, including the Central Neutralization Facility (CNF) and the Toxic Substances Control Act (TSCA) incinerator. The BMAP consists of four tasks: (1) toxicity monitoring; (2) bioaccumulation monitoring; (3) assessment of fish health; and (4) instream monitoring of biological communities, including benthic macroinvertebrates and fish. This document, the third in a series, reports on the results of the Oak Ridge K-25 Site BMAP; it describes studies that were conducted over various periods of time between June 1990 and December 1993, although monitoring conducted outside this time period is included, as appropriate.

  11. Tank farms hazards assessment

    SciTech Connect (OSTI)

    Broz, R.E.

    1994-09-30

    Hanford contractors are writing new facility specific emergency procedures in response to new and revised US Department of Energy (DOE) Orders on emergency preparedness. Emergency procedures are required for each Hanford facility that has the potential to exceed the criteria for the lowest level emergency, an Alert. The set includes: (1) a facility specific procedure on Recognition and Classification of Emergencies, (2) area procedures on Initial Emergency Response and, (3) an area procedure on Protective Action Guidance. The first steps in developing these procedures are to identify the hazards at each facility, identify the conditions that could release the hazardous material, and calculate the consequences of the releases. These steps are called a Hazards Assessment. The final product is a document that is similar in some respects to a Safety Analysis Report (SAR). The document could br produced in a month for a simple facility but could take much longer for a complex facility. Hanford has both types of facilities. A strategy has been adopted to permit completion of the first version of the new emergency procedures before all the facility hazards Assessments are complete. The procedures will initially be based on input from a task group for each facility. This strategy will but improved emergency procedures in place sooner and therefore enhance Hanford emergency preparedness. The purpose of this document is to summarize the applicable information contained within the Waste Tank Facility ``Interim Safety Basis Document, WHC-SD-WM-ISB-001`` as a resource, since the SARs covering Waste Tank Operations are not current in all cases. This hazards assessment serves to collect, organize, document and present the information utilized during the determination process.

  12. Appendix PA: Performance Assessment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for the Waste Isolation Pilot Plant Appendix PA-2014 Performance Assessment United States Department of Energy Waste Isolation Pilot Plant Carlsbad Field Office Carlsbad, New Mexico Compliance Recertification Application 2014 Appendix PA Table of Contents PA-1.0 Introduction PA-1.1 Changes since the CRA-2009 PA PA-1.1.1 Replacement of Option D with the ROMPCS PA-1.1.2 Additional Mined Volume in the Repository North End PA-1.1.3 Refinement to the Probability of Encountering Pressurized Brine

  13. Model Fire Protection Assessment Guide

    Broader source: Energy.gov [DOE]

    This Assessment guide covers the implementation of the DOE's responsibility of assuring that DOE and the DOE Contractors have established Fire Protection Programs that are at the level required for the area being assessed.

  14. Industrial Process Heating - Technology Assessment

    Energy Savers [EERE]

    Industrial Process Heating - Technology Assessment 1 2 Contents 3 4 1. Introduction to the Technology/System ............................................................................................... 2 5 1.1. Industrial Process Heating Overview ............................................................................................ 2 6 2. Technology Assessment and Potential ................................................................................................. 6 7 2.1. Status

  15. Agenda: Preliminary Assessment Development Teleconference

    Broader source: Energy.gov [DOE]

    Document serves as a standard agenda for the teleconference to discuss the in-progress preliminary assessment.

  16. ORISE: Dose modeling and assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dose modeling and assessments The Oak Ridge Institute for Science and Education (ORISE) offers dose modeling and assessment services to demonstrate that federal and/or state regulatory compliance requirements are being met during the decontamination and decommissioning of nuclear facilities. Dose modeling is an important step in the assessment of safety and regulatory compliance, as well as the development of standards and regulatory rulemaking. The ultimate goal of dose modeling and assessments

  17. Integrated Assessment | Open Energy Information

    Open Energy Info (EERE)

    URI: cleanenergysolutions.orgcontenttimes-integrated-assessment-model-0,h Language: English Policies: Deployment Programs DeploymentPrograms: Technical Assistance...

  18. EA-0372: Final Environmental Assessment

    Broader source: Energy.gov [DOE]

    Energy Conservation Standards for Consumer Products: Refrigerators, Furnaces and Television Sets including Environmental Assessment Regulatory Impact Analysis

  19. EA-1906: Draft Environmental Assessment

    Broader source: Energy.gov [DOE]

    Draft Environmental Assessment for Operations, Upgrades, and Consolidation at the Western Command Site, New Mexico, April 2012

  20. Utility of Social Modeling for Proliferation Assessment - Preliminary Assessment

    SciTech Connect (OSTI)

    Coles, Garill A.; Gastelum, Zoe N.; Brothers, Alan J.; Thompson, Sandra E.

    2009-06-01

    This Preliminary Assessment draft report will present the results of a literature search and preliminary assessment of the body of research, analysis methods, models and data deemed to be relevant to the Utility of Social Modeling for Proliferation Assessment research. This report will provide: 1) a description of the problem space and the kinds of information pertinent to the problem space, 2) a discussion of key relevant or representative literature, 3) a discussion of models and modeling approaches judged to be potentially useful to the research, and 4) the next steps of this research that will be pursued based on this preliminary assessment. This draft report represents a technical deliverable for the NA-22 Simulations, Algorithms, and Modeling (SAM) program. Specifically this draft report is the Task 1 deliverable for project PL09-UtilSocial-PD06, Utility of Social Modeling for Proliferation Assessment. This project investigates non-traditional use of social and cultural information to improve nuclear proliferation assessment, including nonproliferation assessment, proliferation resistance assessments, safeguards assessments and other related studies. These assessments often use and create technical information about the State’s posture towards proliferation, the vulnerability of a nuclear energy system to an undesired event, and the effectiveness of safeguards. This project will find and fuse social and technical information by explicitly considering the role of cultural, social and behavioral factors relevant to proliferation. The aim of this research is to describe and demonstrate if and how social science modeling has utility in proliferation assessment.

  1. Computer Security Risk Assessment

    Energy Science and Technology Software Center (OSTI)

    1992-02-11

    LAVA/CS (LAVA for Computer Security) is an application of the Los Alamos Vulnerability Assessment (LAVA) methodology specific to computer and information security. The software serves as a generic tool for identifying vulnerabilities in computer and information security safeguards systems. Although it does not perform a full risk assessment, the results from its analysis may provide valuable insights into security problems. LAVA/CS assumes that the system is exposed to both natural and environmental hazards and tomore » deliberate malevolent actions by either insiders or outsiders. The user in the process of answering the LAVA/CS questionnaire identifies missing safeguards in 34 areas ranging from password management to personnel security and internal audit practices. Specific safeguards protecting a generic set of assets (or targets) from a generic set of threats (or adversaries) are considered. There are four generic assets: the facility, the organization''s environment; the hardware, all computer-related hardware; the software, the information in machine-readable form stored both on-line or on transportable media; and the documents and displays, the information in human-readable form stored as hard-copy materials (manuals, reports, listings in full-size or microform), film, and screen displays. Two generic threats are considered: natural and environmental hazards, storms, fires, power abnormalities, water and accidental maintenance damage; and on-site human threats, both intentional and accidental acts attributable to a perpetrator on the facility''s premises.« less

  2. Risk assessment handbook

    SciTech Connect (OSTI)

    Farmer, F.G.; Jones, J.L.; Hunt, R.N.; Roush, M.L.; Wierman, T.E.

    1990-09-01

    The Probabilistic Risk Assessment Unit at EG G Idaho has developed this handbook to provide guidance to a facility manager exploring the potential benefit to be gained by performance of a risk assessment properly scoped to meet local needs. This document is designed to help the manager control the resources expended commensurate with the risks being managed and to assure that the products can be used programmatically to support future needs in order to derive maximum beneflt from the resources expended. We present a logical and functional mapping scheme between several discrete phases of project definition to ensure that a potential customer, working with an analyst, is able to define the areas of interest and that appropriate methods are employed in the analysis. In addition the handbook is written to provide a high-level perspective for the analyst. Previously, the needed information was either scattered or existed only in the minds of experienced analysts. By compiling this information and exploring the breadth of knowledge which exists within the members of the PRA Unit, the functional relationships between the customers' needs and the product have been established.

  3. Risk assessment handbook

    SciTech Connect (OSTI)

    Farmer, F.G.; Jones, J.L.; Hunt, R.N.; Roush, M.L.; Wierman, T.E.

    1990-09-01

    The Probabilistic Risk Assessment Unit at EG&G Idaho has developed this handbook to provide guidance to a facility manager exploring the potential benefit to be gained by performance of a risk assessment properly scoped to meet local needs. This document is designed to help the manager control the resources expended commensurate with the risks being managed and to assure that the products can be used programmatically to support future needs in order to derive maximum beneflt from the resources expended. We present a logical and functional mapping scheme between several discrete phases of project definition to ensure that a potential customer, working with an analyst, is able to define the areas of interest and that appropriate methods are employed in the analysis. In addition the handbook is written to provide a high-level perspective for the analyst. Previously, the needed information was either scattered or existed only in the minds of experienced analysts. By compiling this information and exploring the breadth of knowledge which exists within the members of the PRA Unit, the functional relationships between the customers` needs and the product have been established.

  4. Biological responses to engineered nanomaterials: Needs for the next decade

    SciTech Connect (OSTI)

    Murphy, Catherine J.; Vartanian, Ariane M.; Geiger, Franz M.; Hamers, Robert J.; Pedersen, Joel A.; Cui, Qiang; Haynes, Christy L.; Carlson, Erin E.; Hernandez, Rigoberto; Klaper, Rebecca D.; Orr, Galya; Rosenzweig, Ze'ev

    2015-06-09

    In this study, the interaction of nanomaterials with biomolecules, cells, and organisms is an enormously vital area of current research, with applications in nanoenabled diagnostics, imaging agents, therapeutics, and contaminant removal technologies. Yet the potential for adverse biological and environmental impacts of nanomaterial exposure is considerable and needs to be addressed to ensure sustainable development of nanomaterials. In this Outlook four research needs for the next decade are outlined: (i) measurement of the chemical nature of nanomaterials in dynamic, complex aqueous environments; (ii) real-time measurements of nanomaterial-biological interactions with chemical specificity; (iii) delineation of molecular modes of action for nanomaterial effects on living systems as functions of nanomaterial properties; and (iv) an integrated systems approach that includes computation and simulation across orders of magnitude in time and space.

  5. Biological responses to engineered nanomaterials: Needs for the next decade

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Murphy, Catherine J.; Vartanian, Ariane M.; Geiger, Franz M.; Hamers, Robert J.; Pedersen, Joel A.; Cui, Qiang; Haynes, Christy L.; Carlson, Erin E.; Hernandez, Rigoberto; Klaper, Rebecca D.; et al

    2015-06-09

    In this study, the interaction of nanomaterials with biomolecules, cells, and organisms is an enormously vital area of current research, with applications in nanoenabled diagnostics, imaging agents, therapeutics, and contaminant removal technologies. Yet the potential for adverse biological and environmental impacts of nanomaterial exposure is considerable and needs to be addressed to ensure sustainable development of nanomaterials. In this Outlook four research needs for the next decade are outlined: (i) measurement of the chemical nature of nanomaterials in dynamic, complex aqueous environments; (ii) real-time measurements of nanomaterial-biological interactions with chemical specificity; (iii) delineation of molecular modes of action for nanomaterialmore » effects on living systems as functions of nanomaterial properties; and (iv) an integrated systems approach that includes computation and simulation across orders of magnitude in time and space.« less

  6. Biology Division. Progress report, August 1, 1982-September 30, 1983

    SciTech Connect (OSTI)

    Not Available

    1984-01-01

    The Biology Division is the component of the Oak Ridge National Laboratory that investigates the potential adverse health effects of energy-related substances. The body of this report provides summaries of the aims, scope and progress of the research of groups of investigators in the Division during the period of August 1, 1982, through September 30, 1983. At the end of each summary is a list of publications covering the same period (published or accepted for publication). For convenience, the summaries are assembled under Sections in accordance with the current organizational structure of the Biology Division; each Section begins with an overview. It will be apparent, however, that currents run throughout the Division and that the various programs support and interact with each other.

  7. Flow-through biological conversion of lignocellulosic biomass

    DOE Patents [OSTI]

    Herring, Christopher D.; Liu, Chaogang; Bardsley, John

    2014-07-01

    The present invention is directed to a process for biologically converting carbohydrates from lignocellulosic biomass comprising the steps of: suspending lignocellulosic biomass in a flow-through reactor, passing a reaction solution into the reactor, wherein the solution is absorbed into the biomass substrate and at least a portion of the solution migrates through said biomass substrate to a liquid reservoir, recirculating the reaction solution in the liquid reservoir at least once to be absorbed into and migrate through the biomass substrate again. The biological converting of the may involve hydrolyzing cellulose, hemicellulose, or a combination thereof to form oligosaccharides, monomelic sugars, or a combination thereof; fermenting oligosaccharides, monomelic sugars, or a combination thereof to produce ethanol, or a combination thereof. The process can further comprise removing the reaction solution and processing the solution to separate the ethanol produced from non-fermented solids.

  8. Using the Gene Ontology to Enrich Biological Pathways

    SciTech Connect (OSTI)

    Sanfilippo, Antonio P.; Baddeley, Robert L.; Beagley, Nathaniel; McDermott, Jason E.; Riensche, Roderick M.; Taylor, Ronald C.; Gopalan, Banu

    2009-12-10

    Most current approaches to automatic pathway generation are based on a reverse engineering approach in which pathway plausibility is solely derived from microarray gene expression data. These approaches tend to lack in generality and offer no independent validation as they are too reliant on the pathway observables that guide pathway generation. By contrast, alternative approaches that use prior biological knowledge to validate pathways inferred from gene expression data may err in the opposite direction as the prior knowledge is usually not sufficiently tuned to the pathology of focus. In this paper, we present a novel pathway generation approach that combines insights from the reverse engineering and knowledge-based approaches to increase the biological plausibility of automatically generated regulatory networks and describe an application of this approach to transcriptional data from a mouse model of neuroprotection during stroke.

  9. Synthetic Biology: Engineering, Evolution and Design (SEED) Conference 2014

    SciTech Connect (OSTI)

    Voigt, Christopher

    2014-07-01

    SEED2014 focused on advances in the science and technology emerging from the field of synthetic biology. We broadly define this as technologies that accelerate the process of genetic engineering. It highlighted new tool development, as well as the application of these tools to diverse problems in biotechnology, including therapeutics, industrial chemicals and fuels, natural products, and agriculture. Systems spanned from in vitro experiments and viruses, through diverse bacteria, to eukaryotes (yeast, mammalian cells, plants).

  10. In Situ Biological Uranium Remediation within a Highly Contaminated Aquifer

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    In Situ Biological Uranium Remediation within a Highly Contaminated Aquifer Matthew Ginder-Vogel1, Wei-Min Wu1, Jack Carley2, Phillip Jardine2, Scott Fendorf1 and Craig Criddle1 1Stanford University, Stanford, CA 2Oak Ridge National Laboratory, Oak Ridge, TN Microbial Respiration Figure 1. Uranium(VI) reduction is driven by microbial respiration resulting in the precipitation of uraninite. Uranium contamination of ground and surface waters has been detected at numerous sites throughout the

  11. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  12. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  13. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  14. American Society of Agricultural and Biological Engineers Annual International Meeting

    Broader source: Energy.gov [DOE]

    The 2015 American Society of Agricultural and Biological Engineers Annual International Meeting will be held in New Orleans, Louisiana on July 26–29, 2015, and will examine industry trends and innovations, with a focus on the focus on the economic, political and social factors influencing the industry. Bioenergy Technologies Office Director Jonathan Male, Program Manager Alison Goss Eng, and Technology Managers Sam Tagore, Mark Elless, and Steve Thomas will be in attendance.

  15. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  16. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  17. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  18. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  19. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  20. Electronic Structure and Excited State Dynamics in Biological and Nanoscale

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systems | MIT-Harvard Center for Excitonics Electronic Structure and Excited State Dynamics in Biological and Nanoscale Systems February 25, 2009 at 3pm/36-428 Gregory D. Scholes Department of Chemistry, University of Toronto scholes2 abstract: After photoexcitation, energy absorbed by a molecule can be transferred efficiently over a distance of up to several tens of Ångstrom to another molecule by the process of resonance energy transfer, RET (also commonly known as electronic energy

  1. CHRONOLOGY OF EVENTS IN DIVISION OF BIOLOGY AND MEDICINE PROGRAMS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CHRONOLOGY OF EVENTS IN DIVISION OF BIOLOGY AND MEDICINE PROGRAMS 1927 1936 December 1944 1946 August 1947 Discovery of the specific mutagenic effects of ionizing radiation by Muller. First cyclotron-produced radioisotope, phosphorus 32, administered to a patient suffering from leukemia at University of California, Berkeley. Initiation of first large scale mammalian genetics study (in mice) at the University of Rochester. First shipment of reactor-produced radioisotope, carbon 14, to independent

  2. Centauri High School Teacher Honored as Colorado Outstanding Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cement (2010 MECS) Cement (2010 MECS) Manufacturing Energy and Carbon Footprint for Cement Sector (NAICS 327310) Energy use data source: 2010 EIA MECS (with adjustments) Footprint Last Revised: February 2014 View footprints for other sectors here. Manufacturing Energy and Carbon Footprint PDF icon Cement More Documents & Publications MECS 2006 - Cement Glass and Glass Products (2010 MECS) Textiles Teacher

    Centauri High School Teacher Honored as Colorado Outstanding Biology Teacher For

  3. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  4. Biological Imaging by Soft X-Ray Diffraction Microscopy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Imaging by Soft X-Ray Diffraction Microscopy Print Electron and x-ray microscopes are a valuable tool for both the life and materials sciences, but they are limited in their ability to image with nanometer-scale resolution in three dimensions nonperiodic objects that are several microns in size. To fill this gap, the technique of coherent x-ray diffraction imaging now under development takes advantage of the penetrating power of x rays while simultaneously removing the limitations

  5. Detection of biological molecules using chemical amplification and optical sensors

    DOE Patents [OSTI]

    Van Antwerp, William Peter; Mastrototaro, John Joseph

    2000-01-01

    Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.

  6. Detection of biological molecules using chemical amplification and optical sensors

    DOE Patents [OSTI]

    Van Antwerp, William Peter; Mastrototaro, John Joseph

    2004-10-12

    Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.

  7. Systems Biology in Prokaryote - Eukaryote Symbiosis | Stanford Synchrotron

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Lightsource Systems Biology in Prokaryote - Eukaryote Symbiosis Monday, June 25, 2012 - 12:00pm SLAC, SSRL Main Conference Room, 137-322 Allen M. Orville, Brookhaven National Laboratory Frontier challenges for macromolecular crystallography (MX) now include determining structures of trapped reactive intermediates, large macromolecules and viruses, membrane proteins, protein-protein complexes, and protein-nucleic acid complexes. Although structure and function are intimately linked,

  8. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  9. Finding Balance Between Biological Groundwater Treatment and Treated Injection Water

    SciTech Connect (OSTI)

    Carlson, Mark A.; Nielsen, Kellin R.; Byrnes, Mark E.; Simmons, Sally A.; Morse, John J.; Geiger, James B.; Watkins, Louis E.; McFee, Phillip M.; Martins, K.

    2015-01-14

    At the U.S. Department of Energy’s Hanford Site, CH2M HILL Plateau Remediation Company operates the 200 West Pump and Treat which was engineered to treat radiological and chemical contaminants in groundwater as a result of the site’s former plutonium production years. Fluidized bed bioreactors (FBRs) are used to remove nitrate, metals, and volatile organic compounds. Increasing nitrate concentrations in the treatment plant effluent and the presence of a slimy biomass (a typical microorganism response to stress) in the FBRs triggered an investigation of nutrient levels in the system. Little, if any, micronutrient feed was coming into the bioreactors. Additionally, carbon substrate (used to promote biological growth) was passing through to the injection wells, causing biological fouling of the wells and reduced specific injectivity. Adjustments to the micronutrient feed improved microorganism health, but the micronutrients were being overfed (particularly manganese) plugging the injection wells further. Injection well rehabilitation to restore specific injectivity required repeated treatments to remove the biological fouling and precipitated metal oxides. A combination of sulfamic and citric acids worked well to dissolve metal oxides and sodium hypochlorite effectively removed the biological growth. Intensive surging and development techniques successfully removed clogging material from the injection wells. Ultimately, the investigation and nutrient adjustments took months to restore proper balance to the microbial system and over a year to stabilize injection well capacities. Carefully tracking and managing the FBRs and well performance monitoring are critical to balancing the needs of the treatment system while reducing fouling mechanisms in the injection wells.

  10. CRC handbook of biological effects of electromagnetic fields

    SciTech Connect (OSTI)

    Polk, C. . Dept. of Electrical Engineering); Postow, E. )

    1986-01-01

    This book presents current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers: dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

  11. CRC handbook of biological effects of electromagnetic fields

    SciTech Connect (OSTI)

    Polk, C.; Postow, E.

    1986-01-01

    This book presents the current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

  12. Experimental Data from the Proteomics Research Center for Integrative Biology

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Smith, Richard D.

    The possible roles and importance of proteomics are rapidly growing across essentially all areas of biological research. The precise and comprehensive measurement of levels of expressed proteins and their modified forms can provide new insights into the molecular nature of cell-signaling pathways and networks, the cell cycle, cellular differentiation, and other processes relevant to understanding human health and the progression of various disease states. The ability to characterize protein complexes complements this capability, allowing hypotheses to be tested and the biological system operation to be defined. The Proteomics Research Center for Integrative Biology is a national user facility established and funded by the National Institute of General Medical Sciences component of the National Institutes of Health. This Center has been established to serve the biomedical research community by developing and integrating new proteomic technologies for collaborative and service studies, disseminating the new technologies, and training scientists in their use. The Center is housed in DOEs William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) at the Pacific Northwest National Laboratory.

  13. Polarized Neutron in Structural Biology Present and Future Outlook

    SciTech Connect (OSTI)

    Zhao, Jinkui [ORNL; Robertson, Lee [ORNL; Herwig, Kenneth W [ORNL; Crabb, Don [University of Virginia

    2013-01-01

    Hydrogen has a strong polarization-dependent neutron scattering cross section. This property has been exploited in the study of soft matters, especially biological macromolecules. When a polarized neutron beam is scattered off a polarized hydrogenous sample, the otherwise large hydrogen incoherent cross section is drastically reduced while the coherent signal is significantly increased. Past experiments have demonstrated the potentials and benefits of polarized neutron scattering from soft materials. The main technical challenge of polarized neutron scattering from biological matters lies at sample polarization. Dynamic nuclear polarization is a proven yet rather sophisticated technique. Its complexity is one of the main reasons for the technique's slow adoption. The future of polarized neutron scattering in biology may rest largely in neutron protein crystallography. Polarization of protein crystals is much easier to accomplish, since protein crystals are typically rather small (<<1 mm) and only require small and easy- to-operate polarization apparatuses. In addition, the high resolution nature of neutron protein crystallography means that we will be able to study individual atoms using the polarized neutron scattering technique.

  14. Mathematics and biology: The interface, challenges and opportunities

    SciTech Connect (OSTI)

    Levin, S.A. )

    1992-06-01

    The interface between mathematics and biology has long been a rich area of research, with mutual benefit to each supporting discipline. Traditional areas of investigation, such as population genetics, ecology, neurobiology, and 3-D reconstructions, have flourished, despite a rather meager environment for the funding of such work. In the past twenty years, the kind and scope of such interactions between mathematicians and biologists have changed dramatically, reaching out to encompass areas of both biology and mathematics that previously had not benefited. At the same time, with the closer integration of theory and experiment, and the increased reliance on high-speed computation, the costs of such research grew, though not the opportunities for funding. The perception became reinforced, both within the research community and at funding agencies, that although these interactions were expanding, they were not doing so at the rate necessary to meet the opportunities and needs. A workshop was held in Washington, DC, between April 28 and May 3, 1990 which drew together a broadly based group of researchers to synthesize conclusions from a group of working papers and extended discussions. The result is the report presented here, which we hope will provide a guide and stimulus to research in mathematical and computational biology for at least the next decade. The report identifies a number of grand challenges, representing a broad consensus among the participants.

  15. Experimental Data from the Proteomics Research Center for Integrative Biology

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Smith, Richard D.

    The possible roles and importance of proteomics are rapidly growing across essentially all areas of biological research. The precise and comprehensive measurement of levels of expressed proteins and their modified forms can provide new insights into the molecular nature of cell-signaling pathways and networks, the cell cycle, cellular differentiation, and other processes relevant to understanding human health and the progression of various disease states. The ability to characterize protein complexes complements this capability, allowing hypotheses to be tested and the biological system operation to be defined. The Proteomics Research Center for Integrative Biology is a national user facility established and funded by the National Institute of General Medical Sciences component of the National Institutes of Health. This Center has been established to serve the biomedical research community by developing and integrating new proteomic technologies for collaborative and service studies, disseminating the new technologies, and training scientists in their use. The Center is housed in DOE’s William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) at the Pacific Northwest National Laboratory.

  16. The biology of novel animal genes: Mouse APEX gene knockout

    SciTech Connect (OSTI)

    MacInnes, M.; Altherr, M.R.; Ludwig, D.; Pedersen, R.; Mold, C.

    1997-07-01

    This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The controlled breeding of novel genes into mice, including the gene knockout (KO), or conversely by adding back transgenes provide powerful genetic technologies that together suffice to determine in large part the biological role(s) of novel genes. Inbred mouse remains the best understood and most useful mammalian experimental system available for tackling the biology of novel genes. The major mammalian apurinic/apyrimidinic (AP) endonuclease (APE), is involved in a key step in the repair of spontaneous and induced AP sites in DNA. Efficient repair of these lesions is imperative to prevent the stable incorporation of mutations into the cellular genome which may lead to cell death or transformation. Loss or modulation of base excison repair activity in vivo may elevate the spontaneous mutation rate in cells, and may lead to a substantial increase in the incidence of cancer. Despite extensive biochemical analysis, however, the significance of these individual APE functions in vivo has not been elucidated. Mouse embryonic stem (ES) cells heterozygous for a deletion mutation in APE have been generated and whole animals containing the APE mutation have been derived from these ES cells. Animals homozygous for the APE null mutation die early in gestation, underscoring the biological significance of this DNA repair gene.

  17. Biologically induced concrete deterioration in a wastewater treatment plant assessed by combining microstructural analysis with thermodynamic modeling

    SciTech Connect (OSTI)

    Leemann, A.; Lothenbach, B.; Hoffmann, C.

    2010-08-15

    In the nitrification basins of wastewater treatment plants, deterioration of the concrete surface can occur due to acid attack caused by a nitrifying biofilm covering the concrete. To identify the mechanism of deterioration, concrete cubes of different composition were suspended in an aerated nitrification basin of a wastewater treatment plant for two years and analyzed afterwards. The microstructural investigation reveals that not only dissolution of hydrates takes place, but that calcite precipitation close to the surface occurs leading to the formation of a dense layer. The degree of deterioration of the different cubes correlates with the CaO content of the different cements used. Cements which contain a high fraction of CaO form more calcite offering a better protection against the acid attack. The presence of slag, which lowers the amount CaO in the cement, leads to a faster deterioration of the concrete than observed for samples produced with pure OPC.

  18. NATURAL RESOURCES ASSESSMENT

    SciTech Connect (OSTI)

    D.F. Fenster

    2000-12-11

    The purpose of this report is to summarize the scientific work that was performed to evaluate and assess the occurrence and economic potential of natural resources within the geologic setting of the Yucca Mountain area. The extent of the regional areas of investigation for each commodity differs and those areas are described in more detail in the major subsections of this report. Natural resource assessments have focused on an area defined as the ''conceptual controlled area'' because of the requirements contained in the U.S. Nuclear Regulatory Commission Regulation, 10 CFR Part 60, to define long-term boundaries for potential radionuclide releases. New requirements (proposed 10 CFR Part 63 [Dyer 1999]) have obviated the need for defining such an area. However, for the purposes of this report, the area being discussed, in most cases, is the previously defined ''conceptual controlled area'', now renamed the ''natural resources site study area'' for this report (shown on Figure 1). Resource potential can be difficult to assess because it is dependent upon many factors, including economics (demand, supply, cost), the potential discovery of new uses for resources, or the potential discovery of synthetics to replace natural resource use. The evaluations summarized are based on present-day use and economic potential of the resources. The objective of this report is to summarize the existing reports and information for the Yucca Mountain area on: (1) Metallic mineral and mined energy resources (such as gold, silver, etc., including uranium); (2) Industrial rocks and minerals (such as sand, gravel, building stone, etc.); (3) Hydrocarbons (including oil, natural gas, tar sands, oil shales, and coal); and (4) Geothermal resources. Groundwater is present at the Yucca Mountain site at depths ranging from 500 to 750 m (about 1,600 to 2,500 ft) below the ground surface. Groundwater resources are not discussed in this report, but are planned to be included in the hydrology section of future revisions of the ''Yucca Mountain Site Description'' (CRWMS M&O 2000c).

  19. A framework for combining social impact assessment and risk assessment

    SciTech Connect (OSTI)

    Mahmoudi, Hossein; Environmental Sciences Research Institute, Shahid Beheshti University, G.C. ; Renn, Ortwin; Vanclay, Frank; Hoffmann, Volker; Karami, Ezatollah

    2013-11-15

    An increasing focus on integrative approaches is one of the current trends in impact assessment. There is potential to combine impact assessment with various other forms of assessment, such as risk assessment, to make impact assessment and the management of social risks more effective. We identify the common features of social impact assessment (SIA) and social risk assessment (SRA), and discuss the merits of a combined approach. A hybrid model combining SIA and SRA to form a new approach called, ‘risk and social impact assessment’ (RSIA) is introduced. RSIA expands the capacity of SIA to evaluate and manage the social impacts of risky projects such as nuclear energy as well as natural hazards and disasters such as droughts and floods. We outline the three stages of RSIA, namely: impact identification, impact assessment, and impact management. -- Highlights: • A hybrid model to combine SIA and SRA namely RSIA is proposed. • RSIA can provide the proper mechanism to assess social impacts of natural hazards. • RSIA can play the role of ex-post as well as ex-ante assessment. • For some complicated and sensitive cases like nuclear energy, conducting a RSIA is necessary.

  20. Department of Defense Nuclear/Biological/Chemical (NBC) defense: Annual report to Congress. Annual report

    SciTech Connect (OSTI)

    1997-03-01

    The National Defense Authorization Act for Fiscal Year 1994, Public Law No. 103-160, Section 1703 (50 USC 1522), mandates the consolidation of all Department of Defense chemical and biological (CB) defense programs. As part of this consolidation, the Secretary of Defense is directed to submit an assessment and a description of plans to improve readiness to survive, fight and win in a nuclear, biological and chemical (NBC) contaminated environment. This report contains modernization plan summaries that highlight the Department`s approach to improve current NBC defense equipment and resolve current shortcomings in the program. 50 USC 1522 has been a critical tool for ensuring the elimination of redundant programs, focusing funds on program priorities, and enhancing readiness. While many problems remain in consolidating the NBC defense program, significant and measurable progress has been made in fulfilling the letter and the intent of Congress. There has been a consolidation of the research, development and acquisition organizations for NBC defense, including the consolidation of all research, development, test and evaluation, and procurement funds for NBC defense. There has been significant progress in the development of Joint training, doctrine development, and requirements generation. Modernization and technology plans have been developed that will begin to show real savings and true consolidation of efforts among the Services. The fruits of these plans will be realized over the next few years as the public law has time to take effect and will result in the increased readiness of U.S. forces. The objective of the Department of Defense (DoD) NBC defense program is to enable our forces to survive, fight, and win in NBC warfare environments. Numerous rapidly changing factors continually influence the program and its management.