National Library of Energy BETA

Sample records for binds dashed line

  1. DASH | Open Energy Information

    Open Energy Info (EERE)

    Interface: Website, Mobile Device Website: dash.by Web Application Link: dash.by Cost: Free OpenEI Keyword(s): Featured, Challenge Generated DASH Screenshot References: DASH1...

  2. Valve and dash-pot assembly

    DOE Patents [OSTI]

    Chang, Shih-Chih

    1986-01-01

    A dash-pot valve comprising a cylinder submerged in the fluid of a housing and having a piston attached to a plunger projecting into the path of closing movement of a pivotal valve member. A vortex chamber in said cylinder is provided with tangentially directed inlets to generate vortex flow upon retraction of said plunger and effect increasing resistance against said piston to progressively retard the closing rate of said valve member toward its seat.

  3. Improved valve and dash-pot assembly

    DOE Patents [OSTI]

    Chang, S.C.

    1985-04-23

    A dash-pot valve comprises a cylinder submerged in the fluid of a housing and have a piston attached to a plunger projecting into the path of closing movement of a pivotal valve member. A vortex chamber in said cylinder is provided with targentially directed inlets to generate vortex flow upon retraction of said plunger and effect increasing resistance against said piston to progressively retard the closing rate of said valve member toward its seat.

  4. Development Wells At Fenton Hill HDR Geothermal Area (Dash, Et...

    Open Energy Info (EERE)

    16, 1979. References Z. V. Dash, H. D. Murphy, R. L. Aamodt, R. G. Aguilar, D. W. Brown, D. A. Counce, H. N. Fisher, C. O. Grigsby, H. Keppler, A. W. Laughlin, R. M. Potter,...

  5. Flow Test At Fenton Hill HDR Geothermal Area (Dash, Et Al., 1983...

    Open Energy Info (EERE)

    Jump to: navigation, search GEOTHERMAL ENERGYGeothermal Home Exploration Activity: Flow Test At Fenton Hill HDR Geothermal Area (Dash, Et Al., 1983) Exploration Activity Details...

  6. Flow Test At Fenton Hill HDR Geothermal Area (Dash, 1989) | Open...

    Open Energy Info (EERE)

    Jump to: navigation, search GEOTHERMAL ENERGYGeothermal Home Exploration Activity: Flow Test At Fenton Hill HDR Geothermal Area (Dash, 1989) Exploration Activity Details Location...

  7. Exciton and biexciton dynamics in single self-assembled InAs/InGaAlAs/InP quantum dash emitting near 1.55??m

    SciTech Connect (OSTI)

    Dusanowski, ?.; Syperek, M. Rudno-Rudzi?ski, W.; Mrowi?ski, P.; Sek, G.; Misiewicz, J.; Somers, A.; Reithmaier, J. P.; Hfling, S.; Forchel, A.

    2013-12-16

    Exciton and biexciton dynamics in a single self-assembled InAs/In{sub 0.53}Ga{sub 0.23}Al{sub 0.24}As/InP(001) quantum dash emitting near 1.55??m has been investigated by micro-photoluminescence and time-resolved micro-photoluminescence at T?=?4.2?K. The exciton and biexciton fine structure splitting of ?60??eV, the biexciton binding energy of ?3.5?meV, and the characteristic exciton and biexciton decay times of 2.0??0.1?ns and 1.1??0.1?ns, respectively, have been determined. The measurement of the biexciton and exciton cross-correlation statistics of the photon emission confirmed the cascaded relaxation process. The exciton-to-biexciton decay time ratio and a small fine structure splitting suggest carrier localization within the investigated quantum dash.

  8. Particle trap to sheath non-binding contact for a gas-insulated transmission line having a corrugated outer conductor

    DOE Patents [OSTI]

    Fischer, William H.

    1984-04-24

    A non-binding particle trap to outer sheath contact for use in gas insulated transmission lines having a corrugated outer conductor. The non-binding feature of the contact according to the teachings of the invention is accomplished by having a lever arm rotatably attached to a particle trap by a pivot support axis disposed parallel to the direction of travel of the inner conductor/insulator/particle trap assembly.

  9. Non-binding conductor load bearing roller for a gas-insulated transmission line having a corrugated outer conductor

    DOE Patents [OSTI]

    Fischer, William H.

    1984-01-01

    A gas-insulated transmission line includes a corrugated outer conductor, an inner conductor disposed within and insulated from the outer conductor by means of support insulators and an insulating gas, and a non-binding transport device for supporting and permitting movement of the inner conductor/insulating support assembly axially along the corrugated outer conductor without radial displacement and for moving without binding along corrugations of any slope less than vertical. The transport device includes two movable contacts, such as skids or rollers, supported on a common pivot lever, the pivot lever being rotatably disposed about a pivot lever axis, which pivot lever axis is in turn disposed on the periphery of a support insulator or particle trap if one is used. The movable contacts are separated axially a distance equal to the axial distance between the peaks and valleys of the corrugations of the outer conductor and separated radially a distance equal to the radial distance between the peaks and valleys of the corrugations of the outer conductor. The transport device has the pivot lever axis disposed parallel to the motion of travel of the inner conductor/insulating support assembly.

  10. Proton Delivery and Removal in [Ni(PR2N...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... The total binding energy (E bind , solid line) is broken down into two components: distortion energy (E dis , dashed ... complemented by harmonic thermal and entropic ...

  11. Single photon emission at 1.55??m from charged and neutral exciton confined in a single quantum dash

    SciTech Connect (OSTI)

    Dusanowski, ?. Syperek, M.; Mrowi?ski, P.; Rudno-Rudzi?ski, W.; Misiewicz, J.; S?k, G.; Somers, A.; Kamp, M.; Hfling, S.; Reithmaier, J. P.

    2014-07-14

    We investigate charged and neutral exciton complexes confined in a single self-assembled InAs/InGaAlAs/InP quantum dash emitting at 1.55??m. The emission characteristics have been probed by measuring high-spatial-resolution polarization-resolved photoluminescence and cross-correlations of photon emission statistics at T?=?5?K. The photon auto-correlation histogram of the emission from both the neutral and charged exciton indicates a clear antibunching dip with as-measured g{sup (2)}(0) values of 0.18 and 0.31, respectively. It proves that these exciton complexes confined in single quantum dashes of InP-based material system can act as true single photon emitters being compatible with standard long-distance fiber communication technology.

  12. Magnetic field control of the neutral and charged exciton fine structure in single quantum dashes emitting at 1.55 μm

    SciTech Connect (OSTI)

    Mrowiński, P.; Musiał, A.; Maryński, A.; Syperek, M.; Misiewicz, J.; Sęk, G.; Somers, A.; Reithmaier, J. P.; Höfling, S.

    2015-02-02

    We investigated the neutral and charged exciton fine structure in single InAs/InGaAlAs/InP quantum dashes emitting at 1.55 μm using polarization-resolved microphotoluminescence in a magnetic field. Inverted spin configuration of horizontally [1–10] and vertically [110] polarized transitions has been observed. An in-plane magnetic field of up to 5 Tesla has been applied to tailor the fine structure, and eventually to reduce the splitting of the bright exciton states down to zero. This inverted structure has been observed for all the investigated excitons, making it a characteristic feature for this class of nanostructures with the largest splitting reduction of 170 μeV.

  13. Line Projects

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Grand Coulee Transmission Line Replacement Project Hooper Springs McNary-John Day Montana-to-Washington Transmission System Upgrade Project - M2W Olympia-Grand Coulee No. 1...

  14. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plains and Eastern Clean Line Transmission Line: Comment from Mr. Dyer Plains and Eastern Clean Line Transmission Line: Comment from Sheila Beck Plains and Eastern Clean Line ...

  15. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plains and Eastern Clean Line Transmission Line: Comment from Change.org Plains and Eastern Clean Line Transmission Line: Comment from Mr. Leftwich Plains and Eastern Clean Line ...

  16. Teaching a cell new tricks

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Teaching a cell new tricks Teaching a cell new tricks At Los Alamos National Laboratory, one group has been investigating the cellular mechanism that controls fatty acid synthesis. May 20, 2016 In panel A, a precursor of the fatty acid (the colored figure) is shown in the binding pocket of the transcription regulator. In the upper figure, the dashed red line indicates a strong interaction at a region of the two molecules. Note that in the lower figure, the dashed line is missing, indicating that

  17. Inhibition of selectin binding

    DOE Patents [OSTI]

    Nagy, Jon O.; Spevak, Wayne R.; Dasgupta, Falguni; Bertozzi, Caroline

    1999-01-01

    This invention provides compositions for inhibiting the binding between two cells, one expressing P- or L-selectin on the surface and the other expressing the corresponding ligand. A covalently crosslinked lipid composition is prepared having saccharides and acidic group on separate lipids. The composition is then interposed between the cells so as to inhibit binding. Inhibition can be achieved at an effective oligosaccharide concentration as low as 10.sup.6 fold below that of the free saccharide. Since selectins are involved in recruiting cells to sites of injury, these composition scan be used to palliate certain inflammatory and immunological conditions.

  18. Inhibition of selectin binding

    DOE Patents [OSTI]

    Nagy, Jon O.; Spevak, Wayne R.; Dasgupta, Falguni; Bertozzi, Caroline

    2001-10-09

    This invention provides compositions for inhibiting the binding between two cells, one expressing P- or L-selectin on the surface and the other expressing the corresponding ligand. A covalently crosslinked lipid composition is prepared having saccharides and acidic group on separate lipids. The composition is then interposed between the cells so as to inhibit binding. Inhibition can be achieved at an effective oligosaccharide concentration as low as 10.sup.6 fold below that of the free saccharide. Since selectins are involved in recruiting cells to sites of injury, these composition scan be used to palliate certain inflammatory and immunological conditions.

  19. Inhibition of selectin binding

    DOE Patents [OSTI]

    Nagy, Jon O.; Spevak, Wayne R.; Dasgupta, Falguni; Bertozzi, Carolyn

    1999-10-05

    This invention provides a system for inhibiting the binding between two cells, one expressing P- or L-selectin on the surface and the other expressing the corresponding ligand. A covalently crosslinked lipid composition is prepared having saccharides and acidic group on separate lipids. The composition is then interposed between the cells so as to inhibit binding. Inhibition can be achieved at an effective oligosaccharide concentration as low as 10.sup.6 fold below that of the free saccharide. Since selectins are involved in recruiting cells to sites of injury, this system can be used to palliate certain inflammatory and immunological conditions.

  20. Cellulose binding domain proteins

    DOE Patents [OSTI]

    Shoseyov, O.; Shpiegl, I.; Goldstein, M.; Doi, R.

    1998-11-17

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.

  1. Cellulose binding domain proteins

    DOE Patents [OSTI]

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc; Doi, Roy

    1998-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  2. Anonymous Help Line

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Anonymous Help Line Ombuds Anonymous Help Line Committed to the fair and equitable treatment of all employees, contractors, and persons doing business with the Laboratory. Contact...

  3. Line Equipment Operator

    Broader source: Energy.gov [DOE]

    There are several Line Equipment Operator positions located in Washington and Oregon. A successful candidate in this position will perform Line Equipment Operator work operating trucks and all...

  4. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Comment from Mr. Garrett Plains and Eastern Clean Line Transmission Line: Comment from Ms. Rutherford Plains and Eastern Clean Line Transmission Line: Comment from Ms. Campbell

  5. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Clean Line: Arkansas and Oklahoma Plains and Eastern Clean Line Transmission Line: Comment from Block Plains and Eastern Clean Line: Arkansas and Oklahoma Comment submitted on ...

  6. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Comment from Downwind, LLC Plains and Eastern Clean Line Transmission Line: Comment from Sheila Beck Plains and Eastern Clean Line Transmission Line: Comment from Crystal Yarbrough

  7. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plains and Eastern Clean Line Transmission Line: Comment from Fallon Sanford Plains and Eastern Clean Line Transmission Line: Comment from Mr. Leftwich Plains and Eastern Clean ...

  8. Plains and Eastern Clean Line Transmission Line: Federal Register...

    Office of Environmental Management (EM)

    Plains and Eastern Clean Line Transmission Line: Federal Register Notice, Volume 80, No. 81 - April 28, 2015 Plains and Eastern Clean Line Transmission Line: Federal Register ...

  9. Nuclear reactor overflow line

    DOE Patents [OSTI]

    Severson, Wayne J.

    1976-01-01

    The overflow line for the reactor vessel of a liquid-metal-cooled nuclear reactor includes means for establishing and maintaining a continuous bleed flow of coolant amounting to 5 to 10% of the total coolant flow through the overflow line to prevent thermal shock to the overflow line when the reactor is restarted following a trip. Preferably a tube is disposed concentrically just inside the overflow line extending from a point just inside the reactor vessel to an overflow tank and a suction line is provided opening into the body of liquid metal in the reactor vessel and into the annulus between the overflow line and the inner tube.

  10. Cell Context Dependent p53 Genome-Wide Binding Patterns and Enrichment at Repeats

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Botcheva, Krassimira; McCorkle, Sean R.

    2014-11-21

    The p53 ability to elicit stress specific and cell type specific responses is well recognized, but how that specificity is established remains to be defined. Whether upon activation p53 binds to its genomic targets in a cell type and stress type dependent manner is still an open question. Here we show that the p53 binding to the human genome is selective and cell context-dependent. We mapped the genomic binding sites for the endogenous wild type p53 protein in the human cancer cell line HCT116 and compared them to those we previously determined in the normal cell line IMR90. We reportmore » distinct p53 genome-wide binding landscapes in two different cell lines, analyzed under the same treatment and experimental conditions, using the same ChIP-seq approach. This is evidence for cell context dependent p53 genomic binding. The observed differences affect the p53 binding sites distribution with respect to major genomic and epigenomic elements (promoter regions, CpG islands and repeats). We correlated the high-confidence p53 ChIP-seq peaks positions with the annotated human repeats (UCSC Human Genome Browser) and observed both common and cell line specific trends. In HCT116, the p53 binding was specifically enriched at LINE repeats, compared to IMR90 cells. The p53 genome-wide binding patterns in HCT116 and IMR90 likely reflect the different epigenetic landscapes in these two cell lines, resulting from cancer-associated changes (accumulated in HCT116) superimposed on tissue specific differences (HCT116 has epithelial, while IMR90 has mesenchymal origin). In conclusion, our data support the model for p53 binding to the human genome in a highly selective manner, mobilizing distinct sets of genes, contributing to distinct pathways.« less

  11. Series Transmission Line Transformer

    DOE Patents [OSTI]

    Buckles, Robert A.; Booth, Rex; Yen, Boris T.

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  12. Transmission Business Line

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Transmission Business Line Non-Federal Financing of Transmission Projects - March 2004 Critical paths on the Northwest transmission grid are congested and the system is near or at...

  13. Plains and Eastern Clean Line Transmission Line: Comment from Marshall

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hughes | Department of Energy from Marshall Hughes Plains and Eastern Clean Line Transmission Line: Comment from Marshall Hughes Comment submitted on updated Part 2 application. Comment from Marshall Hughes 07-10-15.pdf (14.91 KB) More Documents & Publications Plains and Eastern Clean Line Transmission Line: Comment from Mr. Dyer Plains and Eastern Clean Line Transmission Line: Comment from Sheila Beck Plains and Eastern Clean Line Transmission Line: Comment from Patti McCutchen

  14. Transmission Line Security Monitor

    ScienceCinema (OSTI)

    None

    2013-05-28

    The Transmission Line Security Monitor is a multi-sensor monitor that mounts directly on high-voltage transmission lines to detect, characterize and communicate terrorist activity, human tampering and threatening conditions around support towers. For more information about INL's critical infrastructure protection research, visit http://www.facebook.com/idahonationallaboratory.

  15. Transmission Line Security Monitor

    SciTech Connect (OSTI)

    2011-01-01

    The Transmission Line Security Monitor is a multi-sensor monitor that mounts directly on high-voltage transmission lines to detect, characterize and communicate terrorist activity, human tampering and threatening conditions around support towers. For more information about INL's critical infrastructure protection research, visit http://www.facebook.com/idahonationallaboratory.

  16. Summary

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    870 nm AOD of 0.5. The two competitive aerosol models fitting within 0.01 error margin (grey area) are shown by dashed and dash-dotted lines. Right: Same as left but with adding...

  17. Flow line sampler

    DOE Patents [OSTI]

    Nicholls, Colin I.

    1992-07-14

    An on-line product sampling apparatus and method for measuring product samples from a product stream (12) in a flow line (14) having a sampling aperture (11), includes a sampling tube (18) for containing product samples removed from flow line (14). A piston (22) removes product samples from the product stream (12) through the sampling aperture (11) and returns samples to product stream (12). A sensor (20) communicates with sample tube (18), and senses physical properties of samples while the samples are within sample tube (18). In one embodiment, sensor (20) comprises a hydrogen transient nuclear magnetic resonance sensor for measuring physical properties of hydrogen molecules.

  18. Coherent soliton communication lines

    SciTech Connect (OSTI)

    Yushko, O. V. Redyuk, A. A.; Fedoruk, M. P.; Turitsyn, S. K.

    2014-11-15

    The data transmission in coherent fiber-optical communication lines using solitons with a variable phase is studied. It is shown that nonlinear coherent structures (solitons) can be applied for effective signal transmission over a long distance using amplitude and optical-phase keying of information. The optimum ratio of the pulse width to the bit slot at which the spectral efficiency (transmitted bits per second and hertz) is maximal is determined. It is shown that soliton fiber-optical communication lines can ensure data transmission at a higher spectral efficiency as compared to traditional communication lines and at a high signal-to-noise ratio.

  19. How Dynein Binds to Microtubules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How Dynein Binds to Microtubules How Dynein Binds to Microtubules Print Wednesday, 29 April 2009 00:00 Cytoplasmic dynein is a protein complex responsible for the transport of a large variety of cargoes, from specific RNAs and proteins to whole organelles, in a directional fashion along microtubules that serve as cellular conveyor belts. Consistent with this central role, cytoplasmic dynein is associated with a number of disease-related processes, including the transport of viruses,

  20. Power line detection system

    DOE Patents [OSTI]

    Latorre, Victor R.; Watwood, Donald B.

    1994-01-01

    A short-range, radio frequency (RF) transmitting-receiving system that provides both visual and audio warnings to the pilot of a helicopter or light aircraft of an up-coming power transmission line complex. Small, milliwatt-level narrowband transmitters, powered by the transmission line itself, are installed on top of selected transmission line support towers or within existing warning balls, and provide a continuous RF signal to approaching aircraft. The on-board receiver can be either a separate unit or a portion of the existing avionics, and can also share an existing antenna with another airborne system. Upon receipt of a warning signal, the receiver will trigger a visual and an audio alarm to alert the pilot to the potential power line hazard.

  1. Power line detection system

    DOE Patents [OSTI]

    Latorre, V.R.; Watwood, D.B.

    1994-09-27

    A short-range, radio frequency (RF) transmitting-receiving system that provides both visual and audio warnings to the pilot of a helicopter or light aircraft of an up-coming power transmission line complex. Small, milliwatt-level narrowband transmitters, powered by the transmission line itself, are installed on top of selected transmission line support towers or within existing warning balls, and provide a continuous RF signal to approaching aircraft. The on-board receiver can be either a separate unit or a portion of the existing avionics, and can also share an existing antenna with another airborne system. Upon receipt of a warning signal, the receiver will trigger a visual and an audio alarm to alert the pilot to the potential power line hazard. 4 figs.

  2. Line Extension Alternatives

    Broader source: Energy.gov [DOE]

    The Public Service Board (PSB) of Vermont developed rules regarding utility line extension requests. While the majority of the rules focus on the procedure followed (and associated fees) for the...

  3. Lineman (Live Line)

    Broader source: Energy.gov [DOE]

    There are several Lineman (Liveline) positions located in Spokane, Washington. A successful candidate in this position will perform construction and maintenance work for live-line on wood and steel...

  4. Maersk Line Equipment guide

    National Nuclear Security Administration (NNSA)

    Maersk Line containers has an average age of less than six years and a stringent maintenance programme ensures they are always ready for service. Each container in our fleet...

  5. Transmission line capital costs

    SciTech Connect (OSTI)

    Hughes, K.R.; Brown, D.R.

    1995-05-01

    The displacement or deferral of conventional AC transmission line installation is a key benefit associated with several technologies being developed with the support of the U.S. Department of Energy`s Office of Energy Management (OEM). Previous benefits assessments conducted within OEM have been based on significantly different assumptions for the average cost per mile of AC transmission line. In response to this uncertainty, an investigation of transmission line capital cost data was initiated. The objective of this study was to develop a database for preparing preliminary estimates of transmission line costs. An extensive search of potential data sources identified databases maintained by the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) as superior sources of transmission line cost data. The BPA and WAPA data were adjusted to a common basis and combined together. The composite database covers voltage levels from 13.8 to 765 W, with cost estimates for a given voltage level varying depending on conductor size, tower material type, tower frame type, and number of circuits. Reported transmission line costs vary significantly, even for a given voltage level. This can usually be explained by variation in the design factors noted above and variation in environmental and land (right-of-way) costs, which are extremely site-specific. Cost estimates prepared from the composite database were compared to cost data collected by the Federal Energy Regulatory Commission (FERC) for investor-owned utilities from across the United States. The comparison was hampered because the only design specifications included with the FERC data were voltage level and line length. Working within this limitation, the FERC data were not found to differ significantly from the composite database. Therefore, the composite database was judged to be a reasonable proxy for estimating national average costs.

  6. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    from Dr. Contreras Plains and Eastern Clean Line Transmission Line: Comment from Dr. Contreras Comment submitted on updated Part 2 application. PDF icon Comment from Dr. Contreras ...

  7. Plains and Eastern Clean Line Transmission Line: Comment from...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ms. Callahan Plains and Eastern Clean Line Transmission Line: Comment from Ms. Callahan Comment submitted on updated Part 2 application. PDF icon Comment from Ms. Callahan ...

  8. Bonneville upgrades lines

    SciTech Connect (OSTI)

    Not Available

    1993-08-30

    A stretch of Bonneville Power Administration transmission line between Spokane and the Grand Coulee Dam is an 82-mile bottleneck as it is the last 115-kv section of [open quotes]road[close quotes] along a 500-kv transmission [open quotes]highway[close quotes]. Soon the administration will change all that. A number of independent and utility powerplants have been proposed in Idaho, Montana and the Spokane, Wash., area during the 1990s. As the operators will need to move their power, Bonneville is planning to build a $144-million, 500-kv line to upgrade the 115-kv section. The agency is planning to use its existing right-of-way.

  9. Synthetic heparin-binding growth factor analogs

    DOE Patents [OSTI]

    Pena, Louis A.; Zamora, Paul; Lin, Xinhua; Glass, John D.

    2007-01-23

    The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.

  10. ONE NEVADA LINE | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE ONE NEVADA LINE PROJECT SUMMARY In February 2011, the Department of Energy issued a $343 million loan guarantee to finance the One Nevada Transmission Line (ON Line) project, a 235-mile, 500 kV AC transmission line capable of carrying 600 MW of power to the grid running

  11. Cellulose binding domain fusion proteins

    DOE Patents [OSTI]

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc A.; Doi, Roy H.

    1998-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  12. Cellulose binding domain fusion proteins

    DOE Patents [OSTI]

    Shoseyov, O.; Yosef, K.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.

    1998-02-17

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.

  13. PLAINS & EASTERN CLEAN LINE TRANSMISSION LINE | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Section 1222 of the Energy Policy Act 2005 » PLAINS & EASTERN CLEAN LINE TRANSMISSION LINE PLAINS & EASTERN CLEAN LINE TRANSMISSION LINE On March 25, 2016, U.S. Secretary of Energy Dr. Ernest Moniz announced that the Department of Energy (DOE) will participate in the development of the Plains & Eastern Clean Line project (Project), a major clean energy infrastructure project. Through section 1222 of the Energy Policy Act of 2005, Congress authorized DOE to promote electric

  14. Plains & Eastern Clean Line Transmission Line - Part 2 Application |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Transmission Line - Part 2 Application Plains & Eastern Clean Line Transmission Line - Part 2 Application In addition to conducting a NEPA review of the proposed Plains & Eastern Clean Line Transmission Line project, DOE will also conduct due diligence on non-NEPA factors such as the project's technical and financial feasibility and whether the project is in the public interest. DOE will conduct a thorough review that includes making all required statutory

  15. Spectroscopic Evidence for the Phase Competition between the...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    results, the back-bending of the pseudogap line (dashed line) in the superconducting dome is suggested. The researchers further expanded their study into the doping dependence....

  16. Printed circuit dispersive transmission line

    DOE Patents [OSTI]

    Ikezi, H.; Lin-Liu, Y.R.; DeGrassie, J.S.

    1991-08-27

    A printed circuit dispersive transmission line structure is disclosed comprising an insulator, a ground plane formed on one surface of the insulator, a first transmission line formed on a second surface of the insulator, and a second transmission line also formed on the second surface of the insulator and of longer length than the first transmission line and periodically intersecting the first transmission line. In a preferred embodiment, the transmission line structure exhibits highly dispersive characteristics by designing the length of one of the transmission line between two adjacent periodic intersections to be longer than the other. 5 figures.

  17. Printed circuit dispersive transmission line

    DOE Patents [OSTI]

    Ikezi, Hiroyuki; Lin-Liu, Yuh-Ren; DeGrassie, John S.

    1991-01-01

    A printed circuit dispersive transmission line structure is disclosed comprising an insulator, a ground plane formed on one surface of the insulator, a first transmission line formed on a second surface of the insulator, and a second transmission line also formed on the second surface of the insulator and of longer length than the first transmission line and periodically intersecting the first transmission line. In a preferred embodiment, the transmission line structure exhibits highly dispersive characteristics by designing the length of one of the transmission line between two adjacent periodic intersections to be longer than the other.

  18. Drill string transmission line

    DOE Patents [OSTI]

    Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Bradford, Kline; Fox, Joe

    2006-03-28

    A transmission line assembly for transmitting information along a downhole tool comprising a pin end, a box end, and a central bore traveling between the pin end and the box end, is disclosed in one embodiment of the invention as including a protective conduit. A transmission line is routed through the protective conduit. The protective conduit is routed through the central bore and the ends of the protective conduit are routed through channels formed in the pin end and box end of the downhole tool. The protective conduit is elastically forced into a spiral or other non-linear path along the interior surface of the central bore by compressing the protective conduit to a length within the downhole tool shorter than the protective conduit.

  19. CRUCIBLE LINING METHOD

    DOE Patents [OSTI]

    Bone, W.H.; Schmidt, W.W.

    1958-11-01

    A method is presented for forming refractory liners in cylindrical reaction vessels used for the reductlon of uranium tetrafluoride to metallic uranium. A preliminary form, having positioning lugs attached thereto, is inserted into the reaction vessel and the refractory powder, usually CaO, is put in the annular space between the form and the inner wall of the reaction vessel. A jolting table is used to compact this charge of liner material ln place, and after thls has been done, the preliminary form is removed and the flnal form or plug is lnserted without disturbing the partially completed lining. The remainder of the lining charge is then introduced and compacted by jolting, after which the form is removed.

  20. How Dynein Binds to Microtubules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How Dynein Binds to Microtubules Print Cytoplasmic dynein is a protein complex responsible for the transport of a large variety of cargoes, from specific RNAs and proteins to whole organelles, in a directional fashion along microtubules that serve as cellular conveyor belts. Consistent with this central role, cytoplasmic dynein is associated with a number of disease-related processes, including the transport of viruses, neurodegeneration, and the mitotic checkpoint malfunctions that lead to

  1. How Dynein Binds to Microtubules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How Dynein Binds to Microtubules Print Cytoplasmic dynein is a protein complex responsible for the transport of a large variety of cargoes, from specific RNAs and proteins to whole organelles, in a directional fashion along microtubules that serve as cellular conveyor belts. Consistent with this central role, cytoplasmic dynein is associated with a number of disease-related processes, including the transport of viruses, neurodegeneration, and the mitotic checkpoint malfunctions that lead to

  2. How Dynein Binds to Microtubules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How Dynein Binds to Microtubules Print Cytoplasmic dynein is a protein complex responsible for the transport of a large variety of cargoes, from specific RNAs and proteins to whole organelles, in a directional fashion along microtubules that serve as cellular conveyor belts. Consistent with this central role, cytoplasmic dynein is associated with a number of disease-related processes, including the transport of viruses, neurodegeneration, and the mitotic checkpoint malfunctions that lead to

  3. How Dynein Binds to Microtubules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How Dynein Binds to Microtubules Print Cytoplasmic dynein is a protein complex responsible for the transport of a large variety of cargoes, from specific RNAs and proteins to whole organelles, in a directional fashion along microtubules that serve as cellular conveyor belts. Consistent with this central role, cytoplasmic dynein is associated with a number of disease-related processes, including the transport of viruses, neurodegeneration, and the mitotic checkpoint malfunctions that lead to

  4. PLAINS & EASTERN CLEAN LINE TRANSMISSION LINE | Department of...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    PLAINS & EASTERN CLEAN LINE TRANSMISSION LINE On March 25, 2016, U.S. Secretary of Energy Dr. Ernest Moniz announced that the Department of Energy (DOE) will participate in the ...

  5. Climate change: Clinton affirms binding emissions reduction policy

    SciTech Connect (OSTI)

    Fairley, P.

    1996-12-04

    In Australia last month President Clinton called for an international agreement to negotiate {open_quotes}legally binding commitments to fight climate change.{close_quotes} His comments affirmed the line the Administration adopted in July and lent prominence to the effort to bring about a treaty by December 1997. Environmentalists welcomed Clinton`s comments, but industry response is divided. The Global Climate Coalition (Washington), of which CMA is a member, has tried to slow negotiations by questioning the scientific consensus on climate change and suggesting {open_quotes}serious damage to the American economy{close_quotes} could result from emissions reduction.

  6. Erythropoietin binding protein from mammalian serum

    DOE Patents [OSTI]

    Clemons, Gisela K.

    1997-01-01

    Purified mammalian erythropoietin binding-protein is disclosed, and its isolation, identification, characterization, purification, and immunoassay are described. The erythropoietin binding protein can be used for regulation of erythropoiesis by regulating levels and half-life of erythropoietin. A diagnostic kit for determination of level of erythropoietin binding protein is also described.

  7. Erythropoietin binding protein from mammalian serum

    DOE Patents [OSTI]

    Clemons, G.K.

    1997-04-29

    Purified mammalian erythropoietin binding-protein is disclosed, and its isolation, identification, characterization, purification, and immunoassay are described. The erythropoietin binding protein can be used for regulation of erythropoiesis by regulating levels and half-life of erythropoietin. A diagnostic kit for determination of level of erythropoietin binding protein is also described. 11 figs.

  8. Synthetic heparin-binding factor analogs

    DOE Patents [OSTI]

    Pena, Louis A.; Zamora, Paul O.; Lin, Xinhua; Glass, John D.

    2010-04-20

    The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a linker, which may be a hydrophobic linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

  9. Plains and Eastern Clean Line Transmission Line: Federal Register Notice,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Volume 80, No. 81 - April 28, 2015 | Department of Energy Federal Register Notice, Volume 80, No. 81 - April 28, 2015 Plains and Eastern Clean Line Transmission Line: Federal Register Notice, Volume 80, No. 81 - April 28, 2015 The Department of Energy (DOE) requests public comment on the first complete application submitted in response to its June 10, 2010 Request for Proposals for New or Upgraded Transmission Line Projects Under Section 1222 of the Energy Policy Act of 2005 in the Federal

  10. EC Transmission Line Materials

    SciTech Connect (OSTI)

    Bigelow, Tim S

    2012-05-01

    The purpose of this document is to identify materials acceptable for use in the US ITER Project Office (USIPO)-supplied components for the ITER Electron cyclotron Heating and Current Drive (ECH&CD) transmission lines (TL), PBS-52. The source of material property information for design analysis shall be either the applicable structural code or the ITER Material Properties Handbook. In the case of conflict, the ITER Material Properties Handbook shall take precedence. Materials selection, and use, shall follow the guidelines established in the Materials Assessment Report (MAR). Materials exposed to vacuum shall conform to the ITER Vacuum Handbook. [Ref. 2] Commercial materials shall conform to the applicable standard (e.g., ASTM, JIS, DIN) for the definition of their grade, physical, chemical and electrical properties and related testing. All materials for which a suitable certification from the supplier is not available shall be tested to determine the relevant properties, as part of the procurement. A complete traceability of all the materials including welding materials shall be provided. Halogenated materials (example: insulating materials) shall be forbidden in areas served by the detritiation systems. Exceptions must be approved by the Tritium System and Safety Section Responsible Officers.

  11. Bipolar pulse forming line

    DOE Patents [OSTI]

    Rhodes, Mark A.

    2008-10-21

    A bipolar pulse forming transmission line module for linear induction accelerators having first, second, third, fourth, and fifth planar conductors which form an interleaved stack with dielectric layers between the conductors. Each conductor has a first end, and a second end adjacent an acceleration axis. The first and second planar conductors are connected to each other at the second ends, the fourth and fifth planar conductors are connected to each other at the second ends, and the first and fifth planar conductors are connected to each other at the first ends via a shorting plate adjacent the first ends. The third planar conductor is electrically connectable to a high voltage source, and an internal switch functions to short a high voltage from the first end of the third planar conductor to the first end of the fourth planar conductor to produce a bipolar pulse at the acceleration axis with a zero net time integral. Improved access to the switch is enabled by an aperture through the shorting plate and the proximity of the aperture to the switch.

  12. Binding Organic Liquids - Energy Innovation Portal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    More Like This Return to Search Binding Organic Liquids Pacific Northwest National Laboratory Contact PNNL About This Technology Technology Marketing Summary Researchers at...

  13. NETL LINES OF DEMARCATION 09282012

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LINES OF DEMARCATION September 28, 2012 Contact: Site Operations Division or ESS&H Division with Questions The oversight, upkeep, and segregation of NETL infrastructure components, including lines of demarcation between ORD and OIO, will be as follows: 1. Common utility headers including gas compression systems that enter or exit the site will be maintained by the Office of Institutional Operations (OIO). A line of responsibility demarcation between OIO and ORD will be established at the

  14. Electric Transmission Line Siting Compact

    Office of Environmental Management (EM)

    ... creates a method for states to site multi-state electric transmission lines. Three 4 levels of organization are provided: 5 A state project review panel within each ...

  15. LINE-ABOVE-GROUND ATTENUATOR

    DOE Patents [OSTI]

    Wilds, R.B.; Ames, J.R.

    1957-09-24

    The line-above-ground attenuator provides a continuously variable microwave attenuator for a coaxial line that is capable of high attenuation and low insertion loss. The device consists of a short section of the line-above- ground plane type transmission lime, a pair of identical rectangular slabs of lossy material like polytron, whose longitudinal axes are parallel to and indentically spaced away from either side of the line, and a geared mechanism to adjust amd maintain this spaced relationship. This device permits optimum fineness and accuracy of attenuator control which heretofore has been difficult to achieve.

  16. Emergency pipe line repair connects subsea pipe lines

    SciTech Connect (OSTI)

    Lerique, M.P.; Thiberge, P. ); Wright, N. )

    1990-11-01

    Emergency repair of any subsea line pipe must form a high-integrity, metal-to-metal seal. This paper presents a remote, diverless repair system that utilizes master flanges, a connector and a spool piece to repair line pipe in deep offshore waters.

  17. Annual Energy Outlook 2013 Early Release Reference Case

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    price per barrel (real 2010 dollars) Sources: U.S. Energy Information Administration, Thomson Reuters Prices shown are quarterly averages: dashed lines are EIA projections...

  18. DockingShop: A Tool for Interactive Molecular Docking Ting-Cheng...

    Office of Scientific and Technical Information (OSTI)

    ... Covalent bond Cova lent bond Hydrogen bond Hydro gen bond monitors the position and ... Figure 3. Small blue spheres represent water. Dashed-blue lines represent hydrogen bonds ...

  19. SSRL Beam Lines Map | Stanford Synchrotron Radiation Lightsource

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SSRL Beam Lines Map Beam Line by Number | Beam Line by Techniques | Photon Source Parameters

  20. Pulse shaping with transmission lines

    DOE Patents [OSTI]

    Wilcox, Russell B.

    1987-01-01

    A method and apparatus for forming shaped voltage pulses uses passive reflection from a transmission line with nonuniform impedance. The impedance of the reflecting line varies with length in accordance with the desired pulse shape. A high voltage input pulse is transmitted to the reflecting line. A reflected pulse is produced having the desired shape and is transmitted by pulse removal means to a load. Light activated photoconductive switches made of silicon can be utilized. The pulse shaper can be used to drive a Pockels cell to produce shaped optical pulses.

  1. Pulse shaping with transmission lines

    DOE Patents [OSTI]

    Wilcox, R.B.

    1985-08-15

    A method and apparatus for forming shaped voltage pulses uses passive reflection from a transmission line with nonuniform impedance. The impedance of the reflecting line varies with length in accordance with the desired pulse shape. A high voltage input pulse is transmitted to the reflecting line. A reflected pulse is produced having the desired shape and is transmitted by pulse removal means to a load. Light activated photoconductive switches made of silicon can be utilized. The pulse shaper can be used to drive a Pockels cell to produce shaped optical pulses.

  2. Electrical transmission line diametrical retainer

    DOE Patents [OSTI]

    Hall, David R.; Hall, Jr., H. Tracy; Pixton, David; Dahlgren, Scott; Sneddon, Cameron; Briscoe, Michael; Fox, Joe

    2004-12-14

    The invention is a mechanism for retaining an electrical transmission line. In one embodiment of the invention it is a system for retaining an electrical transmission line within down hole components. In accordance with one aspect of the invention, the system includes a plurality of downhole components, such as sections of pipe in a drill string. The system also includes a coaxial cable running between the first and second end of a drill pipe, the coaxial cable having a conductive tube and a conductive core within it. The invention allows the electrical transmission line to with stand the tension and compression of drill pipe during routine drilling cycles.

  3. Improved flow cytometer measurement of binding assays

    DOE Patents [OSTI]

    Saunders, G.C.

    1984-05-30

    The invention relates to a method of measuring binding assays carried out with different size particles wherein the binding assay sample is run through a flow cytometer without separating the sample from the marking agent. The amount of a binding reactant present in a sample is determined by providing particles with a coating of binder and also a known quantity of smaller particles with a coating of binder reactant. The binding reactant is the same as the binding reactant present in the sample. The smaller particles also contain a fluorescent chemical. The particles are combined with the sample and the binding reaction is allowed to occur for a set length of time followed by combining the smaller particles with the mixture of the particles and the sample produced and allowing the binding reactions to proceed to equilibrium. The fluorescence and light scatter of the combined mixture is then measured as the combined mixture passes through a flow cytometer equipped with a laser to bring about fluorescence, and the number and strength of fluorescent events are compared. A similar method is also provided for determining the amount of antigen present in the sample by providing spheres with an antibody coating and some smaller spheres with an antigen coating. (LEW)

  4. NETL LINES OF DEMARCATION 09282012

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A line of responsibility demarcation between OIO and ORD will be established at the shutoff on the branch leading to or from an R&D project or laboratory area. OIO will install a ...

  5. Fin-line horn antenna

    DOE Patents [OSTI]

    Reindel, John

    1990-01-01

    A fin line circuit card containing a fin line slot feeds a dipole antenna ich extends a quarterwave outside the waveguide and provides an energy beam focal point at or near the open end of the waveguide. The dipole antenna thus maintains a wide and nearly constant beamwidth, low VSWR and a circular symmetric radiation pattern for use in electronic warfare direction finding and surveillance applications.

  6. Dash for Bikes, Walk for Trikes | National Nuclear Security Administra...

    National Nuclear Security Administration (NNSA)

    thousands of dollars each year for the Savannah River Site's annual Toys for Tots campaign. The fun is profitable enough to raise a significant amount of money to surprise...

  7. Observation Wells At Fenton Hill HDR Geothermal Area (Dash, Et...

    Open Energy Info (EERE)

    Dennis, Donald S. Dreesen, Leigh S. House, Hugh D. Murphy, Bruce A. Robinson, Morton C. Smith (1987) The US Hot Dry Rock Project Additional References Retrieved from "http:...

  8. Letter from Deputy Secretary Poneman to Clean Line Energy Regarding...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Line: Comment from Ms. Schroeder Plains and Eastern Clean Line Transmission Line: Comment from Mr. Zuniga Plains and Eastern Clean Line Transmission Line: Comment from Mr. Cain...

  9. Hardware device binding and mutual authentication

    DOE Patents [OSTI]

    Hamlet, Jason R; Pierson, Lyndon G

    2014-03-04

    Detection and deterrence of device tampering and subversion by substitution may be achieved by including a cryptographic unit within a computing device for binding multiple hardware devices and mutually authenticating the devices. The cryptographic unit includes a physically unclonable function ("PUF") circuit disposed in or on the hardware device, which generates a binding PUF value. The cryptographic unit uses the binding PUF value during an enrollment phase and subsequent authentication phases. During a subsequent authentication phase, the cryptographic unit uses the binding PUF values of the multiple hardware devices to generate a challenge to send to the other device, and to verify a challenge received from the other device to mutually authenticate the hardware devices.

  10. Localized states of a semi-infinite zigzag graphene sheet with impurity lines

    SciTech Connect (OSTI)

    Cunha, A. M. C.; Ahmed, Maher Z.; Cottam, M. G.; Filho, R. N. Costa

    2014-07-07

    The localized states of a semi-infinite zigzag graphene sheet are studied using a tight-binding model that allows for the inclusion of either one or two lines of impurities. These impurity lines of atoms are placed in rows labeled as n (n=1, 2, 3, ), where n=1 is the free edge. The localized defect modes associated with these impurities are studied analytically and numerically within a tridiagonal matrix formalism. For one impurity line, the modes are analyzed according to the position of that line on the sheet, whereas the modes for two impurities are studied also according to their separation and their positions relative to the edge. When an impurity line is located at the edge (n=1), it is found that the edge states are modified. When the impurities are positioned away from an edge (n>1), additional localized modes are found to occur that may be relatively flat in their dispersion.

  11. Coupled ion Binding and Structural Transitions Along the Transport...

    Office of Scientific and Technical Information (OSTI)

    binding primes the transport domain to accept its substrate and triggers extracellular gate opening, which prevents inward domain translocation until substrate binding takes place. ...

  12. Sequestering Uranium from Seawater: Binding Strength and Modes...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sequestering Uranium from Seawater: Binding Strength and Modes of Uranyl Complexes with Glutarimidedioxime Sequestering Uranium from Seawater: Binding Strength and Modes of Uranyl ...

  13. RNA binding protein and binding site useful for expression of recombinant molecules

    DOE Patents [OSTI]

    Mayfield, Stephen P.

    2006-10-17

    The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.

  14. RNA binding protein and binding site useful for expression of recombinant molecules

    DOE Patents [OSTI]

    Mayfield, Stephen

    2000-01-01

    The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.

  15. ONE NEVADA LINE | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ONE NEVADA LINE ONE NEVADA LINE DOE-LPO_Project-Posters_STOR-TRSM_One-Nevada-Line.pdf (323.38 KB) More Documents & Publications STEPHENTOWN SPINDLE CX-011989: Categorical Exclusion Determination CRESCENT DUNES

  16. Statistical line-by-line model for atomic spectra in intermediate...

    Office of Scientific and Technical Information (OSTI)

    Statistical line-by-line model for atomic spectra in intermediate coupling Citation Details In-Document Search Title: Statistical line-by-line model for atomic spectra in ...

  17. X-ray line polarization spectroscopy of Li-like satellite line...

    Office of Scientific and Technical Information (OSTI)

    X-ray line polarization spectroscopy of Li-like satellite line spectra Citation Details In-Document Search Title: X-ray line polarization spectroscopy of Li-like satellite line ...

  18. Increasing the Capacity of Existing Power Lines

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of wind cooling on transmission lines concurrent with wind power generation, identifying additional capacity and line sag and clearance concerns to the ground, or nearby object. ...

  19. Plains and Eastern Clean Line Transmission Line: Comment from Block Plains

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Eastern Clean Line: Arkansas and Oklahoma | Department of Energy Block Plains and Eastern Clean Line: Arkansas and Oklahoma Plains and Eastern Clean Line Transmission Line: Comment from Block Plains and Eastern Clean Line: Arkansas and Oklahoma Comment submitted on updated Part 2 application. Comment from Block Plains & Eastern Clean Line Arkansas and Oklahoma 06-08-15.pdf (1.21 MB) More Documents & Publications Plains and Eastern Clean Line Transmission Line: Comment from Block

  20. Plains and Eastern Clean Line Transmission Line: Comment from Dr. Contreras

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    | Department of Energy Dr. Contreras Plains and Eastern Clean Line Transmission Line: Comment from Dr. Contreras Comment submitted on updated Part 2 application. Comment from Dr. Contreras 6-10-15.pdf (608.36 KB) More Documents & Publications Plains and Eastern Clean Line Transmission Line: Comment from Dr. Contreras Plains and Eastern Clean Line Transmission Line: Comment from Dr. Contreras Plains and Eastern Clean Line Transmission Line: Comment from Dr. Contreras

  1. Coiled transmission line pulse generators

    DOE Patents [OSTI]

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  2. Chemometrics/on-line measurements

    SciTech Connect (OSTI)

    O'Rourke, P.E. )

    1989-11-01

    The possible future of on-line analytical-quality measurements for improved process control and more timely safeguards measurements is examined in the light of a current project at Savannah River. A measurement system involving a fiber-optic spectrophotometer and the application of mathematical techniques called chemometrics is described.

  3. Exciton binding energy in semiconductor quantum dots

    SciTech Connect (OSTI)

    Pokutnii, S. I.

    2010-04-15

    In the adiabatic approximation in the context of the modified effective mass approach, in which the reduced exciton effective mass {mu} = {mu}(a) is a function of the radius a of the semiconductor quantum dot, an expression for the exciton binding energy E{sub ex}(a) in the quantum dot is derived. It is found that, in the CdSe and CdS quantum dots with the radii a comparable to the Bohr exciton radii a{sub ex}, the exciton binding energy E{sub ex}(a) is substantially (respectively, 7.4 and 4.5 times) higher than the exciton binding energy in the CdSe and CdS single crystals.

  4. Flow cytometer measurement of binding assays

    DOE Patents [OSTI]

    Saunders, George C.

    1987-01-01

    A method of measuring the result of a binding assay that does not require separation of fluorescent smaller particles is disclosed. In a competitive binding assay the smaller fluorescent particles coated with antigen compete with antigen in the sample being analyzed for available binding sites on larger particles. In a sandwich assay, the smaller, fluorescent spheres coated with antibody attach themselves to molecules containing antigen that are attached to larger spheres coated with the same antibody. The separation of unattached, fluorescent smaller particles is made unnecessary by only counting the fluorescent events triggered by the laser of a flow cytometer when the event is caused by a particle with a light scatter measurement within a certain range corresponding to the presence of larger particles.

  5. getnim - NIM's Command Line Interface

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    getnim command getnim - NIM's Command Line Interface This page describes the inquiry-only command called getnim that users can use interactively and in scripts to get their account balances. GETNIM(l) NERSC GETNIM(l) NAME getnim - query the NERSC banking database for remaining allocation, resources and repository information SYNOPSIS getnim [ options ] -Rrname or getnim [ options ] -Rrname { -uuid | -Uuname } or getnim [ options ][ -D ] { -uuid | -Uuname } or getnim [ options ] -Rrname { -l | -L

  6. Stabilized sulfur binding using activated fillers

    DOE Patents [OSTI]

    Kalb, Paul D.; Vagin, Vyacheslav P.; Vagin, Sergey P.

    2015-07-21

    A method of making a stable, sulfur binding composite comprising impregnating a solid aggregate with an organic modifier comprising unsaturated hydrocarbons with at least one double or triple covalent bond between adjacent carbon atoms to create a modifier-impregnated aggregate; heating and drying the modifier-impregnated aggregate to activate the surface of the modifier-impregnated aggregate for reaction with sulfur.

  7. Nucleic acids encoding a cellulose binding domain

    DOE Patents [OSTI]

    Shoseyov, O.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.

    1996-03-05

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 15 figs.

  8. Nucleic acids encoding a cellulose binding domain

    DOE Patents [OSTI]

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc A.; Doi, Roy H.

    1996-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  9. In-Line Thermoelectric Module

    SciTech Connect (OSTI)

    Pento, Robert; Marks, James E.; Staffanson, Clifford D.

    1998-07-28

    A thermoelectric module with a plurality of electricity generating units each having a first end and a second end, the units being arranged first end to second end along an-in-line axis. Each unit includes first and second elements each made of a thermoelectric material, an electrically conductive hot member arranged to heat one side of the first element, and an electrically conductive cold member arranged to cool another side of the first element and to cool one side of the second element. The hot member, the first element, the cold member and the second element are supported in a fixture, are electrically connected respectively to provide an electricity generating unit, and are arranged respectively in positions along the in-line axis. The individual components of each generating unit and the respective generating units are clamped in their in-line positions by a loading bolt at one end of the fixture and a stop wall at the other end of the fixture. The hot members may have a T-shape and the cold members an hourglass shape to facilitate heat transfer. The direction of heat transfer through the hot members may be perpendicular to the direction of heat transfer through the cold members, and both of these heat transfer directions maybe perpendicular to the direction-of current flow through the module.

  10. In-line thermoelectric module

    DOE Patents [OSTI]

    Pento, Robert; Marks, James E.; Staffanson, Clifford D.

    2000-01-01

    A thermoelectric module with a plurality of electricity generating units each having a first end and a second end, the units being arranged first end to second end along an in-line axis. Each unit includes first and second elements each made of a thermoelectric material, an electrically conductive hot member arranged to heat one side of the first element, and an electrically conductive cold member arranged to cool another side of the first element and to cool one side of the second element. The hot member, the first element, the cold member and the second element are supported in a fixture, are electrically connected respectively to provide an electricity generating unit, and are arranged respectively in positions along the in-line axis. The individual components of each generating unit and the respective generating units are clamped in their in-line positions by a loading bolt at one end of the fixture and a stop wall at the other end of the fixture. The hot members may have a T-shape and the cold members an hourglass shape to facilitate heat transfer. The direction of heat transfer through the hot members may be perpendicular to the direction of heat transfer through the cold members, and both of these heat transfer directions may be perpendicular to the direction of current flow through the module.

  11. On enabling secure applications through off-line biometric identification

    SciTech Connect (OSTI)

    Davida, G.I.; Frankel, Y.; Matt, B.J.

    1998-04-01

    In developing secure applications and systems, the designers often must incorporate secure user identification in the design specification. In this paper, the authors study secure off line authenticated user identification schemes based on a biometric system that can measure a user`s biometric accurately (up to some Hamming distance). The schemes presented here enhance identification and authorization in secure applications by binding a biometric template with authorization information on a token such as a magnetic strip. Also developed here are schemes specifically designed to minimize the compromise of a user`s private biometrics data, encapsulated in the authorization information, without requiring secure hardware tokens. In this paper the authors furthermore study the feasibility of biometrics performing as an enabling technology for secure system and application design. The authors investigate a new technology which allows a user`s biometrics to facilitate cryptographic mechanisms.

  12. Plains and Eastern Clean Line Transmission Line: Comment from Save The

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ozarks | Department of Energy from Save The Ozarks Plains and Eastern Clean Line Transmission Line: Comment from Save The Ozarks Comment submitted on updated Part 2 application. Comment by Save the Ozarks 07-13-15.pdf (112.79 KB) More Documents & Publications Plains & Eastern Clean Line Transmission Line - Part 2 Application Plains & Eastern Clean Line Project Proposal for New or Upgraded Transmission Line Projects Under Section 1222 of the Energy Policy Act of 2005 Plains and

  13. FB Line Basis for Interim Operation

    SciTech Connect (OSTI)

    Shedrow, B.

    1998-10-19

    The safety analysis of the FB-Line Facility indicates that the operation of FB-Line to support the current mission does not present undue risk to the facility and co-located workers, general public, or the environment.

  14. CXD 4601, Line Yard Fence Project (4601)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Line Yard Fence Project (4601) Y-12 Site Office Oak Ridge, Anderson County, Tennessee The proposed action is to install fencing around the Old Line Yard to provide protected...

  15. O.A.R. 734-055 - Pole Lines, Buried Cables, Pipe lines, Signs...

    Open Energy Info (EERE)

    rules outline the requirements for location, installation, construction, maintenance and use of pole lines, buried cables, pipe lines, signs miscellaneous operations...

  16. Capillary electrophoresis-fluorescence line narrowing system (CE-FLNS) for on-line structural characterization

    DOE Patents [OSTI]

    Jankowiak, R.J.; Small, G.J.; Shields, P.A.

    1999-04-27

    Capillary electrophoresis (CE) is interfaced with low temperature fluorescence line-narrowing (FLN) spectroscopy for on-line structural characterization of separated molecular analytes. 21 figs.

  17. Capillary electrophoresis-fluorescence line narrowing system (CE-FLNS) for on-line structural characterization

    DOE Patents [OSTI]

    Jankowiak, Ryszard J.; Small, Gerald J.; Shields, Peter A.

    1999-04-27

    Capillary electrophoresis (CE) is interfaced with low temperature fluorescence line-narrowing (FLN) spectroscopy for on-line structural characterization of separated molecular analytes.

  18. BPA FINAL Binding Arbitration policy | Department of Energy

    Office of Environmental Management (EM)

    BPA FINAL Binding Arbitration policy BPA FINAL Binding Arbitration policy Alternative dispute resolution (ADR) encompasses a variety of methods that parties may use to resolve disputes without litigation. Arbitration is a private, less formal process in which parties agree to submit a dispute to one or more impartial arbitrators who then render a decision or award. In non-binding arbitration a party is not required to accept the arbitrator's decision. In contrast, a decision or award in binding

  19. Superconducting transmission line particle detector

    DOE Patents [OSTI]

    Gray, K.E.

    1988-07-28

    A microvertex particle detector for use in a high energy physic collider including a plurality of parallel superconducting thin film strips separated from a superconducting ground plane by an insulating layer to form a plurality of superconducting waveguides. The microvertex particle detector indicates passage of a charged subatomic particle by measuring a voltage pulse measured across a superconducting waveguide caused by the transition of the superconducting thin film strip from a superconducting to a non- superconducting state in response to the passage of a charged particle. A plurality of superconducting thin film strips in two orthogonal planes plus the slow electromagnetic wave propagating in a superconducting transmission line are used to resolve N/sup 2/ ambiguity of charged particle events. 6 figs.

  20. Unsplit bipolar pulse forming line

    DOE Patents [OSTI]

    Rhodes, Mark A.

    2011-05-24

    A bipolar pulse forming transmission line module and system for linear induction accelerators having first, second, third, and fourth planar conductors which form a sequentially arranged interleaved stack having opposing first and second ends, with dielectric layers between the conductors. The first and second planar conductors are connected to each other at the first end, and the first and fourth planar conductors are connected to each other at the second end via a shorting plate. The third planar conductor is electrically connectable to a high voltage source, and an internal switch functions to short at the first end a high voltage from the third planar conductor to the fourth planar conductor to produce a bipolar pulse at the acceleration axis with a zero net time integral. Improved access to the switch is enabled by an aperture through the shorting plate and the proximity of the aperture to the switch.

  1. Superconducting transmission line particle detector

    DOE Patents [OSTI]

    Gray, Kenneth E.

    1989-01-01

    A microvertex particle detector for use in a high energy physic collider including a plurality of parallel superconducting thin film strips separated from a superconducting ground plane by an insulating layer to form a plurality of superconducting waveguides. The microvertex particle detector indicates passage of a charged subatomic particle by measuring a voltage pulse measured across a superconducting waveguide caused by the transition of the superconducting thin film strip from a superconducting to a non-superconducting state in response to the passage of a charged particle. A plurality of superconducting thin film strips in two orthogonal planes plus the slow electromagnetic wave propogating in a superconducting transmission line are used to resolve N.sup.2 ambiguity of charged particle events.

  2. Magnetically insulated transmission line oscillator

    DOE Patents [OSTI]

    Bacon, Larry D.; Ballard, William P.; Clark, M. Collins; Marder, Barry M.

    1988-01-01

    A magnetically insulated transmission line oscillator employs self-generated magnetic fields to generate microwave energy. An anode of the oscillator includes slow-wave structures which are formed of a plurality of thin conductive vanes defining cavities therebetween, and a gap is formed between the anode and a cathode of the oscillator. In response to a pulsed voltage applied to the anode and cathode, self-generated magnetic fields arfe produced in a cross-field orientation with respect to the orientation of the electric field between the anode and the cathode. The cross-field magnetic fields insulate the flow of electrons in the gap and confine the flow of electrons within the gap.

  3. Magnetically insulated transmission line oscillator

    DOE Patents [OSTI]

    Bacon, L.D.; Ballard, W.P.; Clark, M.C.; Marder, B.M.

    1987-05-19

    A magnetically insulated transmission line oscillator employs self-generated magnetic fields to generate microwave energy. An anode of the oscillator includes slow-wave structures which are formed of a plurality of thin conductive vanes defining cavities therebetween, and a gap is formed between the anode and a cathode of the oscillator. In response to a pulsed voltage applied to the anode and cathode, self-generated magnetic fields are produced in a cross-field orientation with respect to the orientation of the electric field between the anode and the cathode. The cross-field magnetic fields insulate the flow of electrons in the gap and confine the flow of electrons within the gap. 11 figs.

  4. Coenzyme A Binding to the Aminoglycoside Acetyltransferase (3)-IIIb Increases Conformational Sampling of Antibiotic Binding Site

    SciTech Connect (OSTI)

    Hu, Xiaohu; Norris, Adrianne; Baudry, Jerome Y; Serpersu, Engin H

    2011-01-01

    NMR spectroscopy experiments and molecular dynamics simulations were performed to describe the dynamic properties of the aminoglycoside acetyltransferase (3)-IIIb (AAC) in its apo and coenzyme A (CoASH) bound forms. The {sup 15}N-{sup 1}H HSQC spectra indicate a partial structural change and coupling of the CoASH binding site with another region in the protein upon the CoASH titration into the apo enzyme. Molecular dynamics simulations indicate a significant structural and dynamic variation of the long loop in the antibiotic binding domain in the form of a relatively slow (250 ns), concerted opening motion in the CoASH enzyme complex and that binding of the CoASH increases the structural flexibility of the loop, leading to an interchange between several similar equally populated conformations.

  5. Dual chain synthetic heparin-binding growth factor analogs

    DOE Patents [OSTI]

    Zamora, Paul O.; Pena, Louis A.; Lin, Xinhua

    2009-10-06

    The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

  6. Dual chain synthetic heparin-binding growth factor analogs

    DOE Patents [OSTI]

    Zamora, Paul O.; Pena, Louis A.; Lin, Xinhua

    2012-04-24

    The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

  7. Gene encoding herbicide safener binding protein

    DOE Patents [OSTI]

    Walton, Jonathan D.; Scott-Craig, John S.

    1999-01-01

    The cDNA encoding safener binding protein (SafBP), also referred to as SBP1, is set forth in FIG. 5 and SEQ ID No. 1. The deduced amino acid sequence is provided in FIG. 5 and SEQ ID No. 2. Methods of making and using SBP1 and SafBP to alter a plant's sensitivity to certain herbicides or a plant's responsiveness to certain safeners are also provided, as well as expression vectors, transgenic plants or other organisms transfected with said vectors and seeds from said plants.

  8. Polynucleotides encoding TRF1 binding proteins

    DOE Patents [OSTI]

    Campisi, Judith; Kim, Sahn-Ho

    2002-01-01

    The present invention provides a novel telomere associated protein (Trf1-interacting nuclear protein 2 "Tin2") that hinders the binding of Trf1 to its specific telomere repeat sequence and mediates the formation of a Tin2-Trf1-telomeric DNA complex that limits telomerase access to the telomere. Also included are the corresponding nucleic acids that encode the Tin2 of the present invention, as well as mutants of Tin2. Methods of making, purifying and using Tin2 of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of Tin2 are presented.

  9. Specific albumin binding to microvascular endothelium in culture

    SciTech Connect (OSTI)

    Schnitzer, J.E.; Carley, W.W.; Palade, G.E. )

    1988-03-01

    The specific binding of rat serum albumin (RSA) to confluent microvascular endothelial cells in culture derived from the vasculature of the rat epididymal fat pad was studied at 4{degree}C by radioassay and immunocytochemistry. Radioiodinated RSA ({sup 125}I-RSA) binding to the cells reached equilibrium at {approximately} 20 min incubation. Albumin binding was a slowly saturating function over concentrations ranging from 0.01 to 50 mg/ml. Specific RSA binding with a moderate apparent affinity constant of 1.0 mg/ml and with a maximum binding concentration of 90 ng/cm{sup 2} was immunolocalized with anti-RSA antibody to the outer (free) side of the enothelium. Scatchard analysis of the binding yielded a nonlinear binding curve with a concave-upward shape. Dissociation rate analysis supports negative cooperativity of albumin binding, but multiple binding sites may also be present. Albumin binding fulfilled many requirements for ligand specificity including saturability, reversibility, competibility, and dependence on both cell type and cell number. The results are discussed in terms of past in situ investigations on the localization of albumin binding to vascular endothelium and its effect on transendothelial molecular transport.

  10. Conformational Variability of Organophosphorus Hydrolase upon Soman and Paraoxon Binding

    SciTech Connect (OSTI)

    Gomes, Diego Eb; Lins, Roberto D.; Pascutti, Pedro G.; Lei, Chenghong; Soares, Thereza A.

    2011-12-31

    The bacterial enzyme organophosphorus hydrolase (OPH) exhibits both catalytic and substrate promiscuity. It hydrolyzes bonds in a variety of phosphotriester (P-O), phosphonothioate (P-S), phosphofluoridate (P-F) and phosphonocyanate (F-CN) compounds. However, its catalytic efficiency varies markedly for different substrates, limiting the broad-range application of OPH as catalyst in the bioremediation of pesticides and chemical war agents. In the present study, pK{sub a} calculations and multiple explicit-solvent molecular dynamics (MD) simulations were performed to characterize and contrast the structural dynamics of OPH bound to two substrates hydrolyzed with very distinct catalytic efficiencies: the nerve agent soman (O-pinacolyl-methyl-phosphonofluoridate) and the pesticide paraoxon (diethyl p-nitrophenyl phosphate). pK{sub a} calculations for the substrate-bound and unbound enzyme showed a significant pK{sub a} shift from standard values ({Delta}pK{sub a} = {+-} 3 units) for residues 254His and 275Arg. MD simulations of the doubly protonated 254His revealed a dynamic hydrogen bond network connecting the catalytic residue 301Asp via 254His to 232Asp, 233Asp, 275Arg and 235Asp, and is consistent with a previously postulated proton relay mechanism to ferry protons away from the active site with substrates that do not require activation of the leaving group. Hydrogen bonds between 301Asp and 254His were persistent in the OPH-paraoxon complex but not in the OPH-soman one, suggesting a potential role for such interaction in the more efficient hydrolysis of paraoxon over soman by OPH. These results are in line with previous mutational studies of residue 254His, which led to an increase of the catalytic efficiency of OPH over soman yet decreased its efficiency for paraoxon. In addition, comparative analysis of the molecular trajectories for OPH bound to soman and paraoxon suggests that binding of the latter facilitates the conformational transition of OPH from the

  11. Relativistic redshifts in quasar broad lines

    SciTech Connect (OSTI)

    Tremaine, Scott; Shen, Yue; Liu, Xin; Loeb, Abraham E-mail: yshen@obs.carnegiescience.edu E-mail: aloeb@cfa.harvard.edu

    2014-10-10

    The broad emission lines commonly seen in quasar spectra have velocity widths of a few percent of the speed of light, so special- and general-relativistic effects have a significant influence on the line profile. We have determined the redshift of the broad Hβ line in the quasar rest frame (determined from the core component of the [O III] line) for over 20,000 quasars from the Sloan Digital Sky Survey Data Release 7 quasar catalog. The mean redshift as a function of line width is approximately consistent with the relativistic redshift that is expected if the line originates in a randomly oriented Keplerian disk that is obscured when the inclination of the disk to the line of sight exceeds ∼30°-45°, consistent with simple active galactic nucleus unification schemes. This result also implies that the net line-of-sight inflow/outflow velocities in the broad-line region are much less than the Keplerian velocity when averaged over a large sample of quasars with a given line width.

  12. Reflection-Based Python-C++ Bindings

    SciTech Connect (OSTI)

    Generowicz, Jacek; Lavrijsen, Wim T.L.P.; Marino, Massimo; Mato, Pere

    2004-10-14

    Python is a flexible, powerful, high-level language with excellent interactive and introspective capabilities and a very clean syntax. As such, it can be a very effective tool for driving physics analysis. Python is designed to be extensible in low-level C-like languages, and its use as a scientific steering language has become quite widespread. To this end, existing and custom-written C or C++ libraries are bound to the Python environment as so-called extension modules. A number of tools for easing the process of creating such bindings exist, such as SWIG and Boost. Python. Yet, the process still requires a considerable amount of effort and expertise. The C++ language has few built-in introspective capabilities, but tools such as LCGDict and CINT add this by providing so-called dictionaries: libraries that contain information about the names, entry points, argument types, etc. of other libraries. The reflection information from these dictionaries can be used for the creation of bindings and so the process can be fully automated, as dictionaries are already provided for many end-user libraries for other purposes, such as object persistency. PyLCGDict is a Python extension module that uses LCG dictionaries, as PyROOT uses CINT reflection information, to allow /cwPython users to access C++ libraries with essentially no preparation on the users' behalf. In addition, and in a similar way, PyROOT gives ROOT users access to Python libraries.

  13. Single transmission line data acquisition system

    DOE Patents [OSTI]

    Fasching, George E.

    1984-01-01

    A single transmission line interrogated multiple channel data acquisition system is provided in which a plurality of remote station/sensors monitor specific process variables and transmit measurement values over the single transmission line to a master station when addressed by the master station. Power for all remote stations (up to 980) is provided by driving the line with constant voltage supplied from the master station and automatically maintained independent of the number of remote stations directly connected to the line. The transmission line can be an RG-62 coaxial cable with lengths up to about 10,000 feet with branches up to 500 feet. The remote stations can be attached randomly along the line. The remote stations can be scanned at rates up to 980 channels/second.

  14. NSLS-II Transport Line Progress

    SciTech Connect (OSTI)

    Fliller R. P.; Wahl, W.; Anderson, A.; Benish, B.; DeBoer, W.; Ganetis, G.; Heese, R.; Hseuh, H.-C.; Hu, J.-P.; Johanson, M.P.; Kosciuk, B.N.; Padrazo, D.; Roy, K.; Shaftan, T.; Singh, O.; Tuozzolo, J.; Wang, G.

    2012-05-20

    The National Synchrotron Light Source II (NSLS-II) is a state-of-the-art 3-GeV third generation light source currently under construction at Brookhaven National Laboratory. The NSLS-II injection system consists of a 200 MeV linac, a 3-GeV booster synchrotron and associated transfer lines. The first part of the Linac to Booster Transport (LBT) line has been installed for linac commissioning. This part includes all components necessary to commission the NSLS-II linac. The second part of this transport line is undergoing installation. Initial results of hardware commissioning will be discussed. The Booster to Storage Ring (BSR) transport line underwent a design review. The first part of the BSR transport line, consisting of all components necessary to commission the booster will be installed in 2012 for booster commissioning. We report on the final design of the BSR line along with the plan to commission the booster.

  15. Microsoft Word - STO Comments on Clean Line Application under...

    Broader source: Energy.gov (indexed) [DOE]

    Clean Line Transmission Line Project ("Clean Line Project" or "Project"). ... "objective of integrating more renewable resources onto the grid," 1 However, after reviewing Section ...

  16. Salt Waste Processing Facility, Line Management Review Board...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Line Management Review Board Charter Salt Waste Processing Facility, Line Management Review Board Charter The Line Management Review Board (LMRB) serves an important oversight ...

  17. Strengthening Line Management Oversight and Federal Monitoring...

    Office of Environmental Management (EM)

    Strengthening Line Management Oversight and Federal Monitoring of Nuclear Facilities Standard Review Plan Volume 4 - Nuclear Safety Basis Program Review During Facility ...

  18. Detonator comprising a nonlinear transmission line

    DOE Patents [OSTI]

    Elizondo-Decanini, Juan M

    2014-12-30

    Detonators are described herein. In a general embodiment, the detonator includes a nonlinear transmission line that has a variable capacitance. Capacitance of the nonlinear transmission line is a function of voltage on the nonlinear transmission line. The nonlinear transmission line receives a voltage pulse from a voltage source and compresses the voltage pulse to generate a trigger signal. Compressing the voltage pulse includes increasing amplitude of the voltage pulse and decreasing length of the voltage pulse in time. An igniter receives the trigger signal and detonates an explosive responsive to receipt of the trigger signal.

  19. DOE Sustainability Reporting Open Line Help Call

    Broader source: Energy.gov [DOE]

    The Sustainability Performance Office (SPO) sponsors open line help calls to assist DOE sites and national laboratories with the annual sustainability reporting process. Representatives from the...

  20. Northern Pass Transmission Line Project Environmental Impact...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Northern Pass Transmission Line Project Environmental Impact Statement: Announcement of Change in Public Meeting Location: Federal Register Notice Volume 78, No. 181 - September ...

  1. MMW Drilling & Lining | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    MMW Drilling & Lining presentation at the April 2013 peer review meeting held in Denver, Colorado. mmwdrillingpeer2013.pdf (1 MB) More Documents & Publications Microhole Arrays ...

  2. Supervisory Transmission Lines and Substation Maintenance Manager

    Broader source: Energy.gov [DOE]

    (See Frequently Asked Questions for more information). Where would I be working? Western Area Power Administration Desert Southwest Region Transmission Lines and Substation Maintenance (G5200) 615...

  3. Transmission Line Security Monitor: Final Report

    SciTech Connect (OSTI)

    John Svoboda

    2011-04-01

    The Electric Power Transmission Line Security Monitor System Operational Test is a project funded by the Technical Support Working Group (TSWG). TSWG operates under the Combating Terrorism Technical Support Office that functions under the Department of Defense. The Transmission Line Security Monitor System is based on technology developed by Idaho National Laboratory. The technology provides a means for real-time monitoring of physical threats and/or damage to electrical transmission line towers and conductors as well as providing operational parameters to transmission line operators to optimize transmission line operation. The end use is for monitoring long stretches of transmission lines that deliver electrical power from remote generating stations to cities and industry. These transmission lines are generally located in remote transmission line corridors where security infrastructure may not exist. Security and operational sensors in the sensor platform on the conductors take power from the transmission line and relay security and operational information to operations personnel hundreds of miles away without relying on existing infrastructure. Initiated on May 25, 2007, this project resulted in pre-production units tested in realistic operational environments during 2010. A technology licensee, Lindsey Manufacturing of Azusa California, is assisting in design, testing, and ultimately production. The platform was originally designed for a security monitoring mission, but it has been enhanced to include important operational features desired by electrical utilities.

  4. AFV CoverSheet

    Office of Scientific and Technical Information (OSTI)

    ... black line and the analytically derived green dash-dotted line on the basis of Eq. (10) ... It can be seen that for increasing kinetic energy of the particles the suppression of the ...

  5. Neptunium Binding Kinetics with Arsenazo(III)

    SciTech Connect (OSTI)

    Leigh R. Martin; Aaron T. Johnson; Stephen P. Mezyk

    2014-08-01

    This document has been prepared to meet FCR&D level 2 milestone M2FT-14IN0304021, Report on the results of actinide binding kinetics with aqueous phase complexants This work was carried out under the auspices of the Thermodynamics and Kinetics of Advanced Separations Systems FCR&D work package. The report details kinetics experiments that were performed to measure rates of aqueous phase complexation for pentavalent neptunium with the chromotropic dye Arsenazo III (AAIII). The studies performed were designed to determine how pH, ionic strength and AAIII concentration may affect the rate of the reaction. A brief comparison with hexavalent neptunium is also made. It was identified that as pH was increased the rate of reaction also increased, however increasing the ionic strength and concentration of AAIII had the opposite effect. Interestingly, the rate of reaction of Np(VI) with AAIII was found to be slower than that of the Np(V) reaction.

  6. Method And Apparatus For Detecting Chemical Binding

    DOE Patents [OSTI]

    Warner, Benjamin P.; Havrilla, George J.; Miller, Thomasin C.; Wells, Cyndi A.

    2005-02-22

    The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass through the size exclusion filter, and then sending a solution of one or more potential pharmaceutical chemicals (preferably an aqueous solution) through the same conduit to the size exclusion filter after target binder has collected on the filter. The potential pharmaceutical chemicals are small enough to pass through the filter. Afterwards, x-rays are sent from an x-ray source to the size exclusion filter, and if the potential pharmaceutical chemicals form a complex with the target binder, the complex produces an x-ray fluorescence signal having an intensity that indicates that a complex has formed.

  7. Method and apparatus for detecting chemical binding

    DOE Patents [OSTI]

    Warner, Benjamin P.; Havrilla, George J.; Miller, Thomasin C.; Wells, Cyndi A.

    2007-07-10

    The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass through the size exclusion filter, and then sending a solution of one or more potential pharmaceutical chemicals (preferably an aqueous solution) through the same conduit to the size exclusion filter after target binder has collected on the filter. The potential pharmaceutical chemicals are small enough to pass through the filter. Afterwards, x-rays are sent from an x-ray source to the size exclusion filter, and if the potential pharmaceutical chemicals form a complex with the target binder, the complex produces an x-ray fluorescence signal having an intensity that indicates that a complex has formed.

  8. Hardware device to physical structure binding and authentication

    DOE Patents [OSTI]

    Hamlet, Jason R.; Stein, David J.; Bauer, Todd M.

    2013-08-20

    Detection and deterrence of device tampering and subversion may be achieved by including a cryptographic fingerprint unit within a hardware device for authenticating a binding of the hardware device and a physical structure. The cryptographic fingerprint unit includes an internal physically unclonable function ("PUF") circuit disposed in or on the hardware device, which generate an internal PUF value. Binding logic is coupled to receive the internal PUF value, as well as an external PUF value associated with the physical structure, and generates a binding PUF value, which represents the binding of the hardware device and the physical structure. The cryptographic fingerprint unit also includes a cryptographic unit that uses the binding PUF value to allow a challenger to authenticate the binding.

  9. Binding Behavior of Dopamine Transporter Key to Understanding...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Understanding Chemical Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Print Wednesday, 09 December 2015 00:00 ...

  10. U-183: ISC BIND DNS Resource Records Handling Vulnerability

    Broader source: Energy.gov [DOE]

    This problem was uncovered while testing with experimental DNS record types. It is possible to add records to BIND with null (zero length) rdata fields.

  11. The Effects of Somatic Hypermutation on Neutralization and Binding...

    Office of Scientific and Technical Information (OSTI)

    Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies Citation Details In-Document Search Title: The Effects of Somatic...

  12. X-ray crystallographic analysis of adipocyte fatty acid binding...

    Office of Scientific and Technical Information (OSTI)

    X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified ... LIFE SCIENCES; ALDEHYDES; CARBOXYLIC ACIDS; CRYSTAL STRUCTURE; IN VIVO; INFLAMMATION; ...

  13. Hydrodynamic and Membrane Binding Properties of Purified Rous...

    Office of Scientific and Technical Information (OSTI)

    Purified Rous Sarcoma Virus Gag Protein Citation Details In-Document Search Title: Hydrodynamic and Membrane Binding Properties of Purified Rous Sarcoma Virus Gag Protein ...

  14. Fragment-Based Exploration of Binding Site Flexibility in Mycobacteriu...

    Office of Scientific and Technical Information (OSTI)

    in Mycobacterium tuberculosis BioA Citation Details In-Document Search Title: Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA Authors: ...

  15. Paul D. Boyer, Adenosine Triphosphate (ATP), and the Binding...

    Office of Scientific and Technical Information (OSTI)

    Paul D. Boyer, Adenosine Triphosphate (ATP), and the Binding Change Mechanism Resources with Additional Information Paul D. Boyer Courtesy of UCLA 'For Paul Boyer, the Nobel Prize ...

  16. Soliton production with nonlinear homogeneous lines

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Elizondo-Decanini, Juan M.; Coleman, Phillip D.; Moorman, Matthew W.; Petney, Sharon Joy Victor; Dudley, Evan C.; Youngman, Kevin; Penner, Tim Dwight; Fang, Lu; Myers, Katherine M.

    2015-11-24

    Low- and high-voltage Soliton waves were produced and used to demonstrate collision and compression using diode-based nonlinear transmission lines. Experiments demonstrate soliton addition and compression using homogeneous nonlinear lines. We built the nonlinear lines using commercially available diodes. These diodes are chosen after their capacitance versus voltage dependence is used in a model and the line design characteristics are calculated and simulated. Nonlinear ceramic capacitors are then used to demonstrate high-voltage pulse amplification and compression. The line is designed such that a simple capacitor discharge, input signal, develops soliton trains in as few as 12 stages. We also demonstrated outputmore » voltages in excess of 40 kV using Y5V-based commercial capacitors. The results show some key features that determine efficient production of trains of solitons in the kilovolt range.« less

  17. Soliton production with nonlinear homogeneous lines

    SciTech Connect (OSTI)

    Elizondo-Decanini, Juan M.; Coleman, Phillip D.; Moorman, Matthew W.; Petney, Sharon Joy Victor; Dudley, Evan C.; Youngman, Kevin; Penner, Tim Dwight; Fang, Lu; Myers, Katherine M.

    2015-11-24

    Low- and high-voltage Soliton waves were produced and used to demonstrate collision and compression using diode-based nonlinear transmission lines. Experiments demonstrate soliton addition and compression using homogeneous nonlinear lines. We built the nonlinear lines using commercially available diodes. These diodes are chosen after their capacitance versus voltage dependence is used in a model and the line design characteristics are calculated and simulated. Nonlinear ceramic capacitors are then used to demonstrate high-voltage pulse amplification and compression. The line is designed such that a simple capacitor discharge, input signal, develops soliton trains in as few as 12 stages. We also demonstrated output voltages in excess of 40 kV using Y5V-based commercial capacitors. The results show some key features that determine efficient production of trains of solitons in the kilovolt range.

  18. 2014 EIA-821 SURVEY: LINE-BY-LINE REFERENCE GUIDE Kerosene

    U.S. Energy Information Administration (EIA) Indexed Site

    Page 1 2014 EIA-821 SURVEY: LINE-BY-LINE REFERENCE GUIDE Kerosene Line No. Sold directly to consumers for: 1 Residential Use (Non-Farm): * Backup generator * Home heating and cooking * Personal lawn equipment * Exclude: Apartment buildings and Farmhouses 2 Commercial Use: * Apartment building * Bank * Casino * Church * College/School/Institution * Department/Retail store * Environmental clean-up service * Flushing fuel lines * Forestry service * Golf course * Government (federal, state, local,

  19. Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold

    SciTech Connect (OSTI)

    Zhou, Haibin; Chen, Jianfang; Meagher, Jennifer L.; Yang, Chao-Yie; Aguilar, Angelo; Liu, Liu; Bai, Longchuan; Cong, Xin; Cai, Qian; Fang, Xueliang; Stuckey, Jeanne A.; Wang, Shaomeng

    2014-10-02

    Employing a structure-based strategy, we have designed a new class of potent small-molecule inhibitors of the anti-apoptotic proteins Bcl-2 and Bcl-xL. An initial lead compound with a new scaffold was designed based upon the crystal structure of Bcl-xL and U.S. Food and Drug Administration (FDA) approved drugs and was found to have an affinity of 100 {micro}M for both Bcl-2 and Bcl-xL. Linking this weak lead to another weak-affinity fragment derived from Abbott's ABT-737 led to an improvement of the binding affinity by a factor of >10,000. Further optimization ultimately yielded compounds with subnanomolar binding affinities for both Bcl-2 and Bcl-xL and potent cellular activity. The best compound (21) binds to Bcl-xL and Bcl-2 with K{sub i} < 1 nM, inhibits cell growth in the H146 and H1417 small-cell lung cancer cell lines with IC{sub 50} values of 60-90 nM, and induces robust cell death in the H146 cancer cell line at 30-100 nM.

  20. Computing Criticality of Lines in Power Systems

    SciTech Connect (OSTI)

    Pinar, Ali; Reichert, Adam; Lesieutre, Bernard

    2006-10-13

    We propose a computationally efficient method based onnonlinear optimization to identify critical lines, failure of which cancause severe blackouts. Our method computes criticality measure for alllines at a time, as opposed to detecting a single vulnerability,providing a global view of the system. This information on criticality oflines can be used to identify multiple contingencies by selectivelyexploring multiple combinations of broken lines. The effectiveness of ourmethod is demonstrated on the IEEE 30 and 118 bus systems, where we canvery quickly detect the most critical lines in the system and identifysevere multiple contingencies.

  1. Babel Fortran 2003 Binding for Structured Data Types

    SciTech Connect (OSTI)

    Muszala, S; Epperly, T; Wang, N

    2008-05-02

    Babel is a tool aimed at the high-performance computing community that addresses the need for mixing programming languages (Java, Python, C, C++, Fortran 90, FORTRAN 77) in order to leverage the specific benefits of those languages. Scientific codes often rely on structured data types (structs, derived data types) to encapsulate data, and Babel has been lacking in this type of support until recently. We present a new language binding that focuses on their interoperability of C/C++ with Fortran 2003. The new binding builds on the existing Fortran 90 infrastructure by using the iso-c-binding module defined in the Fortran 2003 standard as the basis for C/C++ interoperability. We present the technical approach for the new binding and discuss our initial experiences in applying the binding in FACETS (Framework Application for Core-Edge Transport Simulations) to integrate C++ with legacy Fortran codes.

  2. On-line chemical composition analyzer development

    SciTech Connect (OSTI)

    Garrison, A.A.

    1993-01-01

    This report relates to the development of an on-line Raman analyzer for control of a distillation column. It is divided into: program issues, experimental control system evaluation, energy savings analysis, and reliability analysis. (DLC)

  3. Ames Lab 101: Next Generation Power Lines

    ScienceCinema (OSTI)

    Russell, Alan

    2012-08-29

    Ames Laboratory scientist Alan Russell discusses the need to develop new power lines that are stronger and more conductive as a way to address the problem of the nation's aging and inadequate power grid.

  4. factsheet - trees and power lines - July 2008

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Trees and power lines July 2008 This summer, BPA maintenance crews are inspecting and clearing high-growing vegetation from all 8,500- miles (15,000 circuit miles) of our...

  5. Line Environment, Safety and Health Oversight

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-06-26

    Sets forth the Department's expectations line management environment, safety and health (ES&H) oversight and for the use of contractor self-assessment programs as the cornerstone for this oversight. Canceled by DOE O 226.1.

  6. DNA Assembly Line for Nano-Construction

    ScienceCinema (OSTI)

    Oleg Gang

    2010-01-08

    Building on the idea of using DNA to link up nanoparticles scientists at Brookhaven National Lab have designed a molecular assembly line for high-precision nano-construction. Nanofabrication is essential for exploiting the unique properties of nanoparticl

  7. Electrician - Foreman II (Transmission Lines & Substations) ...

    Broader source: Energy.gov (indexed) [DOE]

    Region Transmission Lines and Substation Maintenance (G5200) 615 S. 43rd Avenue Phoenix, AZ 85009 Duty Location is Page, AZ Find out more about living conditions at this...

  8. Temperatures in the blast furnace refractory lining

    SciTech Connect (OSTI)

    Hebel, R.; Streuber, C.; Steiger, R.; Jeschar, R.

    1995-12-01

    The campaign life duration of a blast furnace is mainly determined by the condition of the refractory lining in heavy-duty zones such as the hearth, bosh, belly and lower stack. To achieve a desired lifetime, the temperature of the lining in these areas thereby proved to be the decisive controllable parameter. Low operating temperatures result in prolonged service life and are attained through high cooling efficiency. Besides the refractory grade chosen, the wear profile is mainly determined by the type of cooling system applied and the cooling intensity. Therefore, an appropriate compromise between long service life and energy losses has to be found in each case. In order to predict the service life of a lining it is important to know the wear condition at all times during the campaign. The paper describes the approaches the authors have made so far on European blast furnaces, on a theoretical and practical basis, on how to analyze the lining wear.

  9. Electrical Transmission Line Diametrical Retention Mechanism

    DOE Patents [OSTI]

    Hall, David R.; Hall, Jr., H. Tracy; Pixton, David; Dahlgren, Scott; Sneddon, Cameron; Briscoe, Michael; Fox, Joe

    2006-01-03

    The invention is a mechanism for retaining an electrical transmission line. In one embodiment of the invention it is a system for retaining an electrical transmission line within downhole components. The invention allows a transmission line to be attached to the internal diameter of drilling components that have a substantially uniform drilling diameter. In accordance with one aspect of the invention, the system includes a plurality of downhole components, such as sections of pipe in a drill string, drill collars, heavy weight drill pipe, and jars. The system also includes a coaxial cable running between the first and second end of a drill pipe, the coaxial cable having a conductive tube and a conductive core within it. The invention allows the electrical transmission line to withstand the tension and compression of drill pipe during routine drilling cycles.

  10. Design of the ILC RTML Extraction Lines

    SciTech Connect (OSTI)

    Seletskiy, S.; Tenenbaum, P.; Walz, D.; Solyak, N.; /Fermilab

    2011-10-17

    The ILC [1] Damping Ring to the Main Linac beamline (RTML) contains three extraction lines (EL). Each EL can be used both for an emergency abort dumping of the beam and tune-up continual train-by-train extraction. Two of the extraction lines are located downstream of the first and second stages of the RTML bunch compressor, and must accept both compressed and uncompressed beam with energy spreads of 2.5% and 0.15%, respectively. In this paper we report on an optics design that allowed minimizing the length of the extraction lines while offsetting the beam dumps from the main line by the distance required for acceptable radiation levels in the service tunnel. The proposed extraction lines can accommodate beams with different energy spreads while at the same time providing the beam size acceptable for the aluminum dump window. The RTML incorporates three extraction lines, which can be used for either an emergency beam abort or for a train-by-train extraction. The first EL is located downstream of the Damping Ring extraction arc. The other two extraction lines are located downstream of each stage of the two-stage bunch compressor. The first extraction line (EL1) receives 5GeV beam with an 0.15% energy spread. The extraction line located downstream of the first stage of bunch compressor (ELBC1) receives both compressed and uncompressed beam, and therefore must accept beam with both 5 and 4.88GeV energy, and 0.15% and 2.5% energy spread, respectively. The extraction line located after the second stage of the bunch compressor (ELBC2) receives 15GeV beam with either 0.15 or 1.8% energy spread. Each of the three extraction lines is equipped with the 220kW aluminum ball dump, which corresponds to the power of the continuously dumped beam with 5GeV energy, i.e., the beam trains must be delivered to the ELBC2 dump at reduced repetition rate.

  11. LINE Commission Visits Idaho National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LINE Commission Visits Idaho National Laboratory Members of the state of Idaho�s Leadership in Nuclear Energy (LINE) Commission recently visited the Idaho National Laboratory and related DOE-Idaho cleanup facilities. These photos show commission members at the Materials and Fuels Complex, where Steve Marschman from INL talks to the commission members, and the Advanced Mixed Waste Treatment Facility. At the AMWTP, members saw the supercompactor as Facility Manager Jeremy Hampton explained how

  12. Increased serum cortisol binding in chronic active hepatitis

    SciTech Connect (OSTI)

    Orbach, O.; Schussler, G.C.

    1989-01-01

    A high serum cortisol concentration, apparently due to increased cortisol-binding globulin (CBG), was found in a patient (index case) with chronic active hepatitis (CAH). We therefore performed further studies to determine whether increased cortisol binding is generally associated with CAH. Serum samples were obtained from 15 hospitalized patients with long-term liver function test elevations but no evidence of cirrhosis, 15 normal subjects without a history of hepatitis, four healthy pregnant women, and 10 alcoholic patients with stigmata of cirrhosis. Serum cortisol binding was measured by an adaptation of a previously described charcoal uptake method. Thyroxine-binding globulin (TBG) and sex hormone-binding globulin were determined by radioimmunoassays. Charcoal uptake of 125I cortisol from sera of normal subjects and additional patients with CAH revealed that increased serum cortisol binding by a saturable site, presumably CBG, was associated with CAH. Cortisol binding was significantly correlated with immunoassayable TBG, suggesting that in CAH, similar mechanisms may be responsible for increasing the serum concentrations of CBG and TBG.

  13. Product Binding Varies Dramatically between Processive and Nonprocessive Cellulase Enzymes

    SciTech Connect (OSTI)

    Bu, L.; Nimlos, M. R.; Shirts, M. R.; Stahlberg, J.; Himmel, M. E.; Crowley, M. F.; Beckham, G. T.

    2012-07-13

    Cellulases hydrolyze {beta}-1,4 glycosidic linkages in cellulose, which are among the most prevalent and stable bonds in Nature. Cellulases comprise many glycoside hydrolase families and exist as processive or nonprocessive enzymes. Product inhibition negatively impacts cellulase action, but experimental measurements of product-binding constants vary significantly, and there is little consensus on the importance of this phenomenon. To provide molecular level insights into cellulase product inhibition, we examine the impact of product binding on processive and nonprocessive cellulases by calculating the binding free energy of cellobiose to the product sites of catalytic domains of processive and nonprocessive enzymes from glycoside hydrolase families 6 and 7. The results suggest that cellobiose binds to processive cellulases much more strongly than nonprocessive cellulases. We also predict that the presence of a cellodextrin bound in the reactant site of the catalytic domain, which is present during enzymatic catalysis, has no effect on product binding in nonprocessive cellulases, whereas it significantly increases product binding to processive cellulases. This difference in product binding correlates with hydrogen bonding between the substrate-side ligand and the cellobiose product in processive cellulase tunnels and the additional stabilization from the longer tunnel-forming loops. The hydrogen bonds between the substrate- and product-side ligands are disrupted by water in nonprocessive cellulase clefts, and the lack of long tunnel-forming loops results in lower affinity of the product ligand. These findings provide new insights into the large discrepancies reported for binding constants for cellulases and suggest that product inhibition will vary significantly based on the amount of productive binding for processive cellulases on cellulose.

  14. HOT GAS LINES IN T TAURI STARS

    SciTech Connect (OSTI)

    Ardila, David R.; Herczeg, Gregory J.; Gregory, Scott G.; Hillenbrand, Lynne A.; Ingleby, Laura; Bergin, Edwin; Bethell, Thomas; Calvet, Nuria; France, Kevin; Brown, Alexander; Edwards, Suzan; Johns-Krull, Christopher; Linsky, Jeffrey L.; Yang, Hao; Valenti, Jeff A.; Abgrall, Herve; Alexander, Richard D.; Brown, Joanna M.; Espaillat, Catherine; Hussain, Gaitee; and others

    2013-07-01

    For Classical T Tauri Stars (CTTSs), the resonance doublets of N V, Si IV, and C IV, as well as the He II 1640 A line, trace hot gas flows and act as diagnostics of the accretion process. In this paper we assemble a large high-resolution, high-sensitivity data set of these lines in CTTSs and Weak T Tauri Stars (WTTSs). The sample comprises 35 stars: 1 Herbig Ae star, 28 CTTSs, and 6 WTTSs. We find that the C IV, Si IV, and N V lines in CTTSs all have similar shapes. We decompose the C IV and He II lines into broad and narrow Gaussian components (BC and NC). The most common (50%) C IV line morphology in CTTSs is that of a low-velocity NC together with a redshifted BC. For CTTSs, a strong BC is the result of the accretion process. The contribution fraction of the NC to the C IV line flux in CTTSs increases with accretion rate, from {approx}20% to up to {approx}80%. The velocity centroids of the BCs and NCs are such that V{sub BC} {approx}> 4 V{sub NC}, consistent with the predictions of the accretion shock model, in at most 12 out of 22 CTTSs. We do not find evidence of the post-shock becoming buried in the stellar photosphere due to the pressure of the accretion flow. The He II CTTSs lines are generally symmetric and narrow, with FWHM and redshifts comparable to those of WTTSs. They are less redshifted than the CTTSs C IV lines, by {approx}10 km s{sup -1}. The amount of flux in the BC of the He II line is small compared to that of the C IV line, and we show that this is consistent with models of the pre-shock column emission. Overall, the observations are consistent with the presence of multiple accretion columns with different densities or with accretion models that predict a slow-moving, low-density region in the periphery of the accretion column. For HN Tau A and RW Aur A, most of the C IV line is blueshifted suggesting that the C IV emission is produced by shocks within outflow jets. In our sample, the Herbig Ae star DX Cha is the only object for which we find a

  15. Modeling of Carbohydrate Binding Modules Complexed to Cellulose

    SciTech Connect (OSTI)

    Nimlos, M. R.; Beckham, G. T.; Bu, L.; Himmel, M. E.; Crowley, M. F.; Bomble, Y. J.

    2012-01-01

    Modeling results are presented for the interaction of two carbohydrate binding modules (CBMs) with cellulose. The family 1 CBM from Trichoderma reesei's Cel7A cellulase was modeled using molecular dynamics to confirm that this protein selectively binds to the hydrophobic (100) surface of cellulose fibrils and to determine the energetics and mechanisms for locating this surface. Modeling was also conducted of binding of the family 4 CBM from the CbhA complex from Clostridium thermocellum. There is a cleft in this protein, which may accommodate a cellulose chain that is detached from crystalline cellulose. This possibility is explored using molecular dynamics.

  16. Binding Preferences, Surface Attachment, Diffusivity, and Orientation of a Family 1 Carbohydrate-Binding Module on Cellulose

    SciTech Connect (OSTI)

    Nimlos, M. R.; Beckham, G. T.; Matthews, J. F.; Bu, L.; Himmel, M. E.; Crowley, M. F.

    2012-06-08

    Cellulase enzymes often contain carbohydrate-binding modules (CBMs) for binding to cellulose. The mechanisms by which CBMs recognize specific surfaces of cellulose and aid in deconstruction are essential to understand cellulase action. The Family 1 CBM from the Trichoderma reesei Family 7 cellobiohydrolase, Cel7A, is known to selectively bind to hydrophobic surfaces of native cellulose. It is most commonly suggested that three aromatic residues identify the planar binding face of this CBM, but several recent studies have challenged this hypothesis. Here, we use molecular simulation to study the CBM binding orientation and affinity on hydrophilic and hydrophobic cellulose surfaces. Roughly 43 {mu}s of molecular dynamics simulations were conducted, which enables statistically significant observations. We quantify the fractions of the CBMs that detach from crystal surfaces or diffuse to other surfaces, the diffusivity along the hydrophobic surface, and the overall orientation of the CBM on both hydrophobic and hydrophilic faces. The simulations demonstrate that there is a thermodynamic driving force for the Cel7A CBM to bind preferentially to the hydrophobic surface of cellulose relative to hydrophilic surfaces. In addition, the simulations demonstrate that the CBM can diffuse from hydrophilic surfaces to the hydrophobic surface, whereas the reverse transition is not observed. Lastly, our simulations suggest that the flat faces of Family 1 CBMs are the preferred binding surfaces. These results enhance our understanding of how Family 1 CBMs interact with and recognize specific cellulose surfaces and provide insights into the initial events of cellulase adsorption and diffusion on cellulose.

  17. Nuclear binding energy and symmetry energy of nuclear matter with modern nucleon-nucleon potentials

    SciTech Connect (OSTI)

    Hassaneen, Kh.S.A.; Abo-Elsebaa, H.M.; Sultan, E.A.; Mansour, H.M.M.

    2011-03-15

    Research Highlights: > The nuclear matter is studied within the Brueckner-Hartree-Fock (BHF) approach employing the most recent accurate nucleon-nucleon potentials. > The results come out by approximating the single particle self-consistent potential with a parabolic form. > We discuss the current status of the Coester line, i.e., density and energy of the various saturation points being strongly linearly correlated. > The nuclear symmetry energy is calculated as the difference between the binding energy of pure neutron matter and that of symmetric nuclear matter. - Abstract: The binding energy of nuclear matter at zero temperature in the Brueckner-Hartree-Fock approximation with modern nucleon-nucleon potentials is studied. Both the standard and continuous choices of single particle energies are used. These modern nucleon-nucleon potentials fit the deuteron properties and are phase shifts equivalent. Comparison with other calculations is made. In addition we present results for the symmetry energy obtained with different potentials, which is of great importance in astrophysical calculation.

  18. Metal binding proteins, recombinant host cells and methods

    DOE Patents [OSTI]

    Summers, Anne O.; Caguiat, Jonathan J.

    2004-06-15

    The present disclosure provides artificial heavy metal binding proteins termed chelons by the inventors. These chelons bind cadmium and/or mercuric ions with relatively high affinity. Also disclosed are coding sequences, recombinant DNA molecules and recombinant host cells comprising those recombinant DNA molecules for expression of the chelon proteins. In the recombinant host cells or transgenic plants, the chelons can be used to bind heavy metals taken up from contaminated soil, groundwater or irrigation water and to concentrate and sequester those ions. Recombinant enteric bacteria can be used within the gastrointestinal tracts of animals or humans exposed to toxic metal ions such as mercury and/or cadmium, where the chelon recombinantly expressed in chosen in accordance with the ion to be rededicated. Alternatively, the chelons can be immobilized to solid supports to bind and concentrate heavy metals from a contaminated aqueous medium including biological fluids.

  19. Linear Scaling of the Exciton Binding Energy versus the Band...

    Office of Scientific and Technical Information (OSTI)

    Linear Scaling of the Exciton Binding Energy versus the Band Gap of Two-Dimensional Materials This content will become publicly available on August 6, 2016 Prev Next Title:...

  20. Visually Relating Gene Expression and in vivo DNA Binding Data

    SciTech Connect (OSTI)

    Huang, Min-Yu; Mackey, Lester; Ker?; nen, Soile V. E.; Weber, Gunther H.; Jordan, Michael I.; Knowles, David W.; Biggin, Mark D.; Hamann, Bernd

    2011-09-20

    Gene expression and in vivo DNA binding data provide important information for understanding gene regulatory networks: in vivo DNA binding data indicate genomic regions where transcription factors are bound, and expression data show the output resulting from this binding. Thus, there must be functional relationships between these two types of data. While visualization and data analysis tools exist for each data type alone, there is a lack of tools that can easily explore the relationship between them. We propose an approach that uses the average expression driven by multiple of ciscontrol regions to visually relate gene expression and in vivo DNA binding data. We demonstrate the utility of this tool with examples from the network controlling early Drosophila development. The results obtained support the idea that the level of occupancy of a transcription factor on DNA strongly determines the degree to which the factor regulates a target gene, and in some cases also controls whether the regulation is positive or negative.

  1. Dynamic Line Rating: Research and Policy Evaluation

    SciTech Connect (OSTI)

    Jake P. Gentle; Kurt S. Myers; Michael R. West

    2014-07-01

    Dynamic Line Rating (DLR) is a smart grid technology that allows the rating of electrical conductors to be increased based on local weather conditions. Overhead lines are conventionally given a conservative rating based on worst case scenarios. We demonstrate that observing the conditions in real time leads to additional capacity and safer operation. This paper provides a report of a pioneering scheme in the United States of America in which DLR has been applied. Thereby, we demonstrate that observing the local weather conditions in real time leads to additional capacity and safer operation. Secondly, we discuss limitations involved. In doing so, we arrive at novel insights which will inform and improve future DLR projects. Third, we provide a policy background and discussion to clarify the technology’s potential and identifies barriers to the imminent adoption of dynamic line rating systems. We provide suggestions for regulatory bodies about possible improvements in policy to encourage adoption of this beneficial technology.

  2. Load-resistant coaxial transmission line

    DOE Patents [OSTI]

    Hall, David R.; Fox, Joe

    2006-01-03

    A transmission line for downhole tools that make up all or part of a tool string for drilling and production of oil, gas, and geothermal wells that can withstand the dynamic gravitational forces and other accelerations associated with downhole excavations. The transmission line has a metal tube, or outer conductor, that houses a coaxial wire inner conductor. A non-metallic dielectric material is interposed between the inner and outer conductors. The outer and inner conductors and the dielectric are sufficiently compressed together so that independent motion between them is abated. Compression of the components of the transmission line may be achieved by drawing the transmission through one or more dies in order to draw down the outer conductor onto the dielectric, or by expanding the inner conductor against the dielectric using a mandrel or hydraulic pressure. Non-metallic bead segments may be used in aid of the compression necessary to resist the dynamic forces and accelerations of drilling.

  3. DNA-Binding Mechanism in Prokaryotic Partition Complex Formation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DNA-Binding Mechanism in Prokaryotic Partition Complex Formation DNA-Binding Mechanism in Prokaryotic Partition Complex Formation Print Wednesday, 29 March 2006 00:00 The faithful inheritance of genetic information, essential for all organisms, requires accurate movement and positioning of replicated DNA to daughter cells during cell division. In cells without distinct nuclei (prokaryotes), this process, called partition or segregation, is mediated by par systems. The prototype system of

  4. Binding Behavior of Dopamine Transporter Key to Understanding Chemical

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Print Wednesday, 09 December 2015 00:00 Most people have heard of adrenaline, the chemical that causes the "fight or flight" reaction in humans. Most people have also heard of the chemical substances cocaine and methamphetamine, which also elicit a particular (perhaps

  5. Characterization of Selective Binding of Alkali Cations with Carboxylate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterization of Selective Binding of Alkali Cations with Carboxylate Characterization of Selective Binding of Alkali Cations with Carboxylate Print Wednesday, 24 September 2008 00:00 During its lifetime, a cell spends a considerable fraction of its energy pumping sodium and calcium out and potassium in. This balancing process is similar to that found in the coils of the DNA double helix, where specific ions nestle and help stabilize this macromolecule. These are only two examples of

  6. Computational Biology: A Recipe for Ligand-Binding Proteins

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computational Biology: A Recipe for Ligand-Binding Proteins Authors: Ghirlanda, G. Title: Computational Biology: A Recipe for Ligand-Binding Proteins Source: Nature Year: 2013 Volume: 501 Pages: 177-178 ABSTRACT: Cellular cross-talk, enzymatic catalysis and regulation of gene expression all depend on molecular recognition. A method that allows the design of proteins with desired recognition sites could thus be revolutionary Date of online publication: Thu, 2013-09-12 Link online:

  7. EC Transmission Line Risk Identification and Analysis

    SciTech Connect (OSTI)

    Bigelow, Tim S

    2012-04-01

    The purpose of this document is to assist in evaluating and planning for the cost, schedule, and technical project risks associated with the delivery and operation of the EC (Electron cyclotron) transmission line system. In general, the major risks that are anticipated to be encountered during the project delivery phase associated with the implementation of the Procurement Arrangement for the EC transmission line system are associated with: (1) Undefined or changing requirements (e.g., functional or regulatory requirements) (2) Underperformance of prototype, first unit, or production components during testing (3) Unavailability of qualified vendors for critical components Technical risks associated with the design and operation of the system are also identified.

  8. 1 and 2-Dimensional Line Transfer Package

    Energy Science and Technology Software Center (OSTI)

    1990-07-01

    LXF1D is a one dimensional steady-state line transfer package designed to handle: overlapping and or interacting lines, planar, cylindrical, spherical (and special) geometries, doppler shifts, complete redistribution (CRD), partial redistribution (PRD). PRD requires the use of REDIST or some other package to produce emission profiles. LXF2D is a two dimensional version of LXF1D for xy and rz geometries. Both LXF1D and LXF2D are designed to be added to existing non-local thermodynamic equilibrium (NLTE) codes withmore » a minimum of effort.« less

  9. Botas line repaired ahead of schedule

    SciTech Connect (OSTI)

    Not Available

    1991-11-01

    This paper reports on damaged sections of Botas' dual 30-in. gas line carrying USSR gas across the Marmara Sea to Turkey that were replaced 30 days ahead of contract schedule. Tefken Construction and Installation Co., Inc., Istanbul, working under a $4-million contract, replaced two sections on one of the dual lines near Ambarli, Turkey, within a two-month period. The offshore system stretches 33-mi under the Marmara Sea with some pipe laid at 262-ft maximum water depths. The scope of the project was to replace a 426-ft offshore approach to the northern shoreline and a 984-ft onshore section, which were damaged by a submarine landslide.

  10. Concurrent Wind Cooling in Power Transmission Lines

    SciTech Connect (OSTI)

    Jake P Gentle

    2012-08-01

    Idaho National Laboratory and the Idaho Power Company, with collaboration from Idaho State University, have been working on a project to monitor wind and other environmental data parameters along certain electrical transmission corridors. The combination of both real-time historical weather and environmental data is being used to model, validate, and recommend possibilities for dynamic operations of the transmission lines for power and energy carrying capacity. The planned results can also be used to influence decisions about proposed design criteria for or upgrades to certain sections of the transmission lines.

  11. MCM ring hexamerization is a prerequisite for DNA-binding

    SciTech Connect (OSTI)

    Froelich, Clifford A.; Nourse, Amanda; Enemark, Eric J.

    2015-09-13

    The hexameric Minichromosome Maintenance (MCM) protein complex forms a ring that unwinds DNA at the replication fork in eukaryotes and archaea. Our recent crystal structure of an archaeal MCM N-terminal domain bound to single-stranded DNA (ssDNA) revealed ssDNA associating across tight subunit interfaces but not at the loose interfaces, indicating that DNA-binding is governed not only by the DNA-binding residues of the subunits (MCM ssDNA-binding motif, MSSB) but also by the relative orientation of the subunits. We now extend these findings to show that DNA-binding by the MCM N-terminal domain of the archaeal organism Pyrococcus furiosus occurs specifically in the hexameric oligomeric form. We show that mutants defective for hexamerization are defective in binding ssDNA despite retaining all the residues observed to interact with ssDNA in the crystal structure. One mutation that exhibits severely defective hexamerization and ssDNA-binding is at a conserved phenylalanine that aligns with the mouse Mcm4(Chaos3) mutation associated with chromosomal instability, cancer, and decreased intersubunit association.

  12. MCM ring hexamerization is a prerequisite for DNA-binding

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Froelich, Clifford A.; Nourse, Amanda; Enemark, Eric J.

    2015-09-13

    The hexameric Minichromosome Maintenance (MCM) protein complex forms a ring that unwinds DNA at the replication fork in eukaryotes and archaea. Our recent crystal structure of an archaeal MCM N-terminal domain bound to single-stranded DNA (ssDNA) revealed ssDNA associating across tight subunit interfaces but not at the loose interfaces, indicating that DNA-binding is governed not only by the DNA-binding residues of the subunits (MCM ssDNA-binding motif, MSSB) but also by the relative orientation of the subunits. We now extend these findings to show that DNA-binding by the MCM N-terminal domain of the archaeal organism Pyrococcus furiosus occurs specifically in themore » hexameric oligomeric form. We show that mutants defective for hexamerization are defective in binding ssDNA despite retaining all the residues observed to interact with ssDNA in the crystal structure. One mutation that exhibits severely defective hexamerization and ssDNA-binding is at a conserved phenylalanine that aligns with the mouse Mcm4(Chaos3) mutation associated with chromosomal instability, cancer, and decreased intersubunit association.« less

  13. Inductive gas line for pulsed lasers (Patent) | DOEPatents

    Office of Scientific and Technical Information (OSTI)

    through the inlet gas feed line. A ferrite core extends through the coil to increase the ... laser; inlet; gas; feed; line; ferrite; core; extends; coil; increase; inductance; ...

  14. Atomic line emission analyzer for hydrogen isotopes (Patent)...

    Office of Scientific and Technical Information (OSTI)

    Atomic line emission analyzer for hydrogen isotopes Title: Atomic line emission analyzer for hydrogen isotopes Apparatus for isotopic analysis of hydrogen comprises a low pressure ...

  15. Independent Oversight Evaluation of Line Self-Assessments of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Evaluation of Line Self-Assessments of Safety Conscious Work Environment - February 2014 Independent Oversight Evaluation of Line Self-Assessments of Safety Conscious Work...

  16. EA-1967: Hills Creek-Lookout Point Transmission Line Rebuild...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    967: Hills Creek-Lookout Point Transmission Line Rebuild, Lane County, Oregon EA-1967: Hills Creek-Lookout Point Transmission Line Rebuild, Lane County, Oregon Summary Bonneville ...

  17. EA-1981: Bonneville-Hood River Transmission Line Rebuild, Multnomah...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    81: Bonneville-Hood River Transmission Line Rebuild, Multnomah and Hood River Counties, Oregon EA-1981: Bonneville-Hood River Transmission Line Rebuild, Multnomah and Hood River ...

  18. EA-1961: Kalispell-Kerr Transmission Line Rebuild Project, Kalispell...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    1: Kalispell-Kerr Transmission Line Rebuild Project, Kalispell and Polson, Montana EA-1961: Kalispell-Kerr Transmission Line Rebuild Project, Kalispell and Polson, Montana SUMMARY ...

  19. Electron Broadening of Isolated Lines with Stationary Non-Equilibrium...

    Office of Scientific and Technical Information (OSTI)

    Title: Electron Broadening of Isolated Lines with Stationary Non-Equilibrium Level Populations It is shown that a quantum kinetic theory approach to line broadening, extended to ...

  20. Strengthening the Front Lines: Sales Training and Continuing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lines: Sales Training and Continuing Education for Contractors Strengthening the Front Lines: Sales Training and Continuing Education for Contractors Better Buildings ...

  1. Arizona Transmission Line Siting Committee | Open Energy Information

    Open Energy Info (EERE)

    Line Siting Committee Jump to: navigation, search Name: Arizona Transmission Line Siting Committee Abbreviation: TLSC Address: 1200 West Washington Street Place: Phoenix, Arizona...

  2. Changes to the Transfer Line Collimation System for the High...

    Office of Scientific and Technical Information (OSTI)

    The transfer line optics will have to be adjusted for the new collimator locations and ... with its implications on transfer line optics and powering, maintainability, protection ...

  3. Sandia Energy - Experts Call for Triple Bottom Line Approach...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Experts Call for Triple Bottom Line Approach to National Energy Policy Home Energy News News & Events Mission VisionMission Experts Call for Triple Bottom Line Approach to...

  4. PVM Lines and Services LLC aka PVML Photovoltaics | Open Energy...

    Open Energy Info (EERE)

    PVM Lines and Services LLC aka PVML Photovoltaics Jump to: navigation, search Name: PVM Lines and Services LLC (aka PVML Photovoltaics) Place: Princeton, New Jersey Zip: 8540...

  5. Glosten Associates Tests Innovative High-Strength Mooring Lines...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Mooring Lines for Deepwater Offshore Wind Installations Glosten Associates Tests Innovative High-Strength Mooring Lines for Deepwater Offshore Wind Installations October 1, ...

  6. EIS-0474: Southline Transmission Line Project; Arizona and New...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Line Project; Arizona and New Mexico EIS-0474: Southline Transmission Line Project; Arizona and New Mexico Summary The Bureau of Land Management and Western ...

  7. Development of aerogel-lined targets for inertial confinement...

    Office of Scientific and Technical Information (OSTI)

    ThesisDissertation: Development of aerogel-lined targets for inertial confinement fusion experiments Citation Details In-Document Search Title: Development of aerogel-lined ...

  8. Plains & Eastern Clean Line Transmission Line- Part 2 Application: Comments Received on the Updated Application

    Broader source: Energy.gov [DOE]

    In December 2014, DOE requested additional information from Clean Line Energy Partners, LLC to supplement and update its original Plains and Eastern Clean Line application. The updated Part 2 application and other documentation were available for a public comment period that closed on July 13, 2015. Comments were posted as they were received.

  9. The same pocket in menin binds both MLL and JUND but has opposite...

    Office of Scientific and Technical Information (OSTI)

    Menin binds the JUN family transcription factor JUND and inhibits its transcriptional ... A recent report on the tethering of MLL1 to chromatin binding factor lens ...

  10. V-172: ISC BIND RUNTIME_CHECK Error Lets Remote Users Deny Service...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ISC BIND RUNTIMECHECK Error Lets Remote Users Deny Service Against Recursive Resolvers V-172: ISC BIND RUNTIMECHECK Error Lets Remote Users Deny Service Against Recursive...

  11. DOE Sustainability Reporting Open Line Help Call

    Broader source: Energy.gov [DOE]

    The Sustainability Performance Office (SPO) sponsors open line help calls to assist DOE sites and national laboratories with the annual sustainability reporting process. Representatives from the SPO will be available on the call to answer specific questions with respect to Site Sustainability Plans (SSP) and the Consolidated Energy Data Report (CEDR).

  12. High temperature lined conduits, elbows and tees

    DOE Patents [OSTI]

    De Feo, Angelo (Passaic, NJ); Drewniany, Edward (Bergen, NJ)

    1982-01-01

    A high temperature lined conduit comprising, a liner, a flexible insulating refractory blanket around and in contact with the liner, a pipe member around the blanket and spaced therefrom, and castable rigid refractory material between the pipe member and the blanket. Anchors are connected to the inside diameter of the pipe and extend into the castable material. The liner includes male and female slip joint ends for permitting thermal expansion of the liner with respect to the castable material and the pipe member. Elbows and tees of the lined conduit comprise an elbow liner wrapped with insulating refractory blanket material around which is disposed a spaced elbow pipe member with castable refractory material between the blanket material and the elbow pipe member. A reinforcing band is connected to the elbow liner at an intermediate location thereon from which extend a plurality of hollow tubes or pins which extend into the castable material to anchor the lined elbow and permit thermal expansion. A method of fabricating the high temperature lined conduit, elbows and tees is also disclosed which utilizes a polyethylene layer over the refractory blanket after it has been compressed to maintain the refractory blanket in a compressed condition until the castable material is in place. Hot gases are then directed through the interior of the liner for evaporating the polyethylene and setting the castable material which permits the compressed blanket to come into close contact with the castable material.

  13. In-line beam current monitor

    DOE Patents [OSTI]

    Ekdahl, C.A. Jr.; Frost, C.A.

    1984-11-13

    An intense relativistic electron beam current monitor for a gas neutralized beam transport line includes a first foil for conducting plasma current to the wall where it is measured as it traverses an inductive loop formed by a cavity in the wall. An insulator foil separates the first foil from a second conducting foil which returns the current to the plasma environment.

  14. In-line beam current monitor

    DOE Patents [OSTI]

    Ekdahl, Jr., Carl A.; Frost, Charles A.

    1986-01-01

    An intense relativistic electron beam current monitor for a gas neutralized beam transport line includes a first foil for conducting plasma current to the wall where it is measured as it traverses an inductive loop formed by a cavity in the wall. An insulator foil separates the first foil from a second conducting foil which returns the current to the plasma environment.

  15. Integrated survey and design for transmission lines

    SciTech Connect (OSTI)

    Miller, M.A.; Simpson, K.D.

    1994-12-31

    Gathering and compiling information on the features and uses of the land within a proposed corridor provides the basis for selecting a route, obtaining easements, and designing and constructing a transmission line. Traditionally, gathering this information involved searches of existing maps and records to obtain the available information, which would then be supplemented with aerial photography to record current conditions. Ground surveys were performed to collect topographic data for design purposes. This information was manually transferred to drawings and other documents to show the terrain, environmentally sensitive areas, property ownership, and existing facilities. These drawing served as the base to which the transmission line right-of-way, structures, and other design information were added. As the design was completed, these drawings became the source of information for constructing the line and ultimately, the record of the facility. New technologies and the every growing need for instantly accessible information have resulted in changes in almost every step of gathering, storing and using information. Electronic data collection, global positioning systems (GPS), digitized terrain models, computerized design techniques, development of drawings using CAD, and graphical information systems (GIS) have individually resulted in significant advancements in this process. Combining these components into an integrated system, however, is truly revolutionizing transmission line engineering. This paper gives an overview of the survey and mapping information that is required for transmission line projects, review the traditional techniques that have been employed to obtain and utilize this information, and discuss the recent advances in the technology. Additionally, a system is presented that integrates the components in this process to achieve efficiency, minimize chances of errors, and provide improved access to project information.

  16. jz502253r 1..7

    Office of Scientific and Technical Information (OSTI)

    ... Pure Resonant Auger -Normal Auger Kinetic Energy (eV) Figure 4. Auger spectra for a neat ... and resonant (spectator + participator, green dashed line) components at 398 eV. (c) ...

  17. Microsoft PowerPoint - FinalModule1.ppt

    Broader source: Energy.gov (indexed) [DOE]

    ... Along with the schedule and cost results discussed, earned value management enables you to forecast the final results of the project (blue dashed line). 0 25 50 75 100 125 150 ...

  18. Stockpile Stewardship Q

    National Nuclear Security Administration (NNSA)

    ... concepts exist, all must bring the fusion fuel to an extreme high-energy-density state. ... liners imploded on the Z Facility. Green and red dashed lines indicate the liner's ...

  19. Report No.: DOE/ DE-FG02-09ER64747-3 DOE Project No.: DE-FG02...

    Office of Scientific and Technical Information (OSTI)

    ... The blue dashed lines denote the initial concentrations of Al (C 0 for Al) in STWL. The green triangle and blue diamond symbols indicate measured effluent Si and Al, respectively. ...

  20. prs_vs_cgc.eps

    Office of Scientific and Technical Information (OSTI)

    ... The area above the diagonal green dashed line corresponds to the BBN constraint for a ... modification in an energy window th a t large neutrino detectors could directly probe. ...

  1. FTA- SunLine Transit Agency- Final Report

    Broader source: Energy.gov [DOE]

    Final Report on the Federal Transit Administration, SunLine Transit Agency Cooperative Agreement (Part One)

  2. In-line real time air monitor

    DOE Patents [OSTI]

    Wise, M.B.; Thompson, C.V.

    1998-07-14

    An in-line gas monitor capable of accurate gas composition analysis in a continuous real time manner even under strong applied vacuum conditions operates by mixing an air sample with helium forming a sample gas in two complementary sample loops embedded in a manifold which includes two pairs of 3-way solenoid valves. The sample gas is then analyzed in an ion trap mass spectrometer on a continuous basis. Two valve drivers actuate the two pairs of 3-way valves in a reciprocating fashion, so that there is always flow through the in-line gas monitor via one or the other of the sample loops. The duty cycle for the two pairs of 3-way valves is varied by tuning the two valve drivers to a duty cycle typically between 0.2 to 0.7 seconds. 3 figs.

  3. In-line real time air monitor

    DOE Patents [OSTI]

    Wise, Marcus B.; Thompson, Cyril V.

    1998-01-01

    An in-line gas monitor capable of accurate gas composition analysis in a continuous real time manner even under strong applied vacuum conditions operates by mixing an air sample with helium forming a sample gas in two complementary sample loops embedded in a manifold which includes two pairs of 3-way solenoid valves. The sample gas is then analyzed in an ion trap mass spectrometer on a continuous basis. Two valve drivers actuate the two pairs of 3-way valves in a reciprocating fashion, so that there is always flow through the in-line gas monitor via one or the other of the sample loops. The duty cycle for the two pairs of 3-way valves is varied by tuning the two valve drivers to a duty cycle typically between 0.2 to 0.7 seconds.

  4. Line-of-sight deposition method

    DOE Patents [OSTI]

    Patten, James W.; McClanahan, Edwin D.; Bayne, Michael A.

    1981-01-01

    A line-of-sight method of depositing a film having substantially 100% of theoretical density on a substrate. A pressure vessel contains a target source having a surface thereof capable of emitting particles therefrom and a substrate with the source surface and the substrate surface positioned such that the source surface is substantially parallel to the direction of the particles impinging upon the substrate surface, the distance between the most remote portion of the substrate surface receiving the particles and the source surface emitting the particles in a direction parallel to the substrate surface being relatively small. The pressure in the vessel is maintained less than about 5 microns to prevent scattering and permit line-of-sight deposition. By this method the angles of incidence of the particles impinging upon the substrate surface are in the range of from about 45.degree. to 90.degree. even when the target surface area is greatly expanded to increase the deposition rate.

  5. Line-of-sight deposition method

    DOE Patents [OSTI]

    Patten, J.W.; McClanahan, E.D.; Bayne, M.A.

    1980-04-16

    A line-of-sight method of depositing a film having substantially 100% of theoretical density on a substrate. A pressure vessel contains a target source having a surface thereof capable of emitting particles therefrom and a substrate with the source surface and the substrate surface positioned such that the source surface is substantially parallel to the direction of the particles impinging upon the substrate surface, the distance between the most remote portion of the substrate surface receiving the particles and the source surface emitting the particles in a direction parallel to the substrate surface being relatively small. The pressure in the vessel is maintained less than about 5 microns to prevent scattering and permit line-of-sight deposition. By this method the angles of incidence of the particles impinging upon the substrate surface are in the range of from about 45/sup 0/ to 90/sup 0/ even when the target surface area is greatly expanded to increase the deposition rate.

  6. Rectangular Dielectric-lined Accelerator Structure

    SciTech Connect (OSTI)

    Wang Changbiao; Yakovlev, V.P.; Hirshfield, J.L.

    2004-12-07

    Results are reported from analysis of a rectangular X-band dielectric-lined accelerator structure operating in the symmetric LSM-11 mode that has a number of favorable attributes, by comparison with dielectric-lined cylindrical structures. These attributes include use of two planar one-piece precision-ground TiN coated dielectric slabs free of joints, open slots along two opposing metallic faces to suppress all anti-symmetric higher-order modes and to facilitate high-speed pumping, and significant reduction of wall losses by use of evanescent vacuum gaps beyond the dielectric slabs. It is shown that a structure operating at 11.424 GHz can be built with a shunt impedance > 60 M{omega}/m using low-loss alumina as the dielectric.

  7. Boron-10 Lined Proportional Counter Model Validation

    SciTech Connect (OSTI)

    Lintereur, Azaree T.; Siciliano, Edward R.; Kouzes, Richard T.

    2012-06-30

    The Department of Energy Office of Nuclear Safeguards (NA-241) is supporting the project “Coincidence Counting With Boron-Based Alternative Neutron Detection Technology” at Pacific Northwest National Laboratory (PNNL) for the development of an alternative neutron coincidence counter. The goal of this project is to design, build and demonstrate a boron-lined proportional tube-based alternative system in the configuration of a coincidence counter. This report discusses the validation studies performed to establish the degree of accuracy of the computer modeling methods current used to simulate the response of boron-lined tubes. This is the precursor to developing models for the uranium neutron coincidence collar under Task 2 of this project.

  8. X-ray line polarization spectroscopy of Li-like satellite line...

    Office of Scientific and Technical Information (OSTI)

    We apply the magnetic-sublevel atomic kinetics model POLAR to the calculation of polarization properties of satellite lines in Li-like Si driven by subpicosecond-duration laser ...

  9. Heavy rains hamper Louisiana gas line

    SciTech Connect (OSTI)

    Horner, C.

    1983-06-01

    Despite heavy rains and flooding a 36-mile gas pipeline loop for Transcontinental Gas Pipe Line Corp. was completed from north of Starks (at the end of Transco's south Louisiana lateral) to the Lake Charles area. Somastic-coated, 42-in. grade X-60 pipe comprises 90% of the route. The contract included multiple 30-42 in. fabrications, installation of six 42-in. gate valves, and expansion of the Gillis compressor station.

  10. Strain monitoring averts line failure in Rockies

    SciTech Connect (OSTI)

    Miller, B.; Bukovansky, M.

    1987-08-10

    The case history of a landslide in the U.S. Rocky Mountains shows that the potential for pipeline monitoring in geologically sensitive areas, those subject to landslides and subsidence, for example. A properly installed monitoring system monitored by the pipeline operator, Western Gas Supply Co. (West Gas), Denver, provided an early warning of increasing line strains. The problem was complicated by rugged topography which is described here. Stability analysis was the key technique utilized in the process.

  11. Gas lines chasing huge northeastern market

    SciTech Connect (OSTI)

    Watts, J.

    1982-03-01

    Gas for the Northeastern US market is the driving force behind three proposed projects to bring Canadian gas to the New England-New York area: the 360-mile New England States pipeline (Algonquin Gas Transmission Co., Transcontinental Gas Pipe Line Corp., Texas Eastern Transmission Corp., and Nova, an Alberta Corp.); the 261-mile Boundary Gas project (with Boundary Gas Inc., a consortium of 14 gas utilities with Tennessee Gas Pipeline Co. providing transportation); and the 158-mile Niagara pipeline (Transcontinental Gas Pipe Line Corp.). Although none has yet received government (US and Canadian) approval, at least one project - the New England States line - is expected to be operational by 1984, bringing 305 million CF of natural gas daily for US residential and industrial markets. Both countries stand to benefit from the three projects. For Canada, the sale of gas to New England provides a steady market for massive quantities of gas makes building a pipeline from gas-rich Alberta (that will also serve eastern Canada) economically feasible, and ensures the existence of a transportation network in the Maritime provinces for use when production begins off Newfoundland and Nova Scotia. For the US, the gas from Canada will help reduce the nation's dependence on foreign oil and provide additional supplies during the peakload winter season.

  12. Transmission line environmental assessment guidance document

    SciTech Connect (OSTI)

    Jackson, J.; Pentecost, E.; Muzzarelli, J.

    1994-01-01

    Since 1939, U.S. utility companies have been required to obtain a Presidential Permit to construct electric transmission lines that cross a U.S. border and connect with a foreign utility. The purpose of this document is to provide Presidential Permit applicants with two types of guidance: (1) on the type of environmental and project descriptive information needed to assess the potential impacts of the proposed and alternative actions and (2) on compliance with applicable federal and state regulations. The main three chapters present information on the purpose and content of this document (Chapter 1); legislative, regulatory, and consultation requirements for transmission line interconnect projects (Chapter 2); and identification of basic transmission system design parameters and environmental data requirements for analysis of potential impacts of the proposed action (Chapter 3). Chapter 3 also includes information on possible techniques or measures to mitigate impacts. Appendix A presents an overview of NEPA requirements and DOE`s implementing procedures. Appendix B summarizes information on legislation that may be applicable to transmission line projects proposed in Presidential Permit applications.

  13. RefreshLine.png | OSTI, US Dept of Energy Office of Scientific and

    Office of Scientific and Technical Information (OSTI)

    Technical Information RefreshLine

  14. Orientation-dependent binding energy of graphene on palladium

    SciTech Connect (OSTI)

    Kappes, Branden B.; Ebnonnasir, Abbas; Ciobanu, Cristian V. [Department of Mechanical Engineering and Materials Science Program, Colorado School of Mines, Golden, Colorado 80401 (United States)] [Department of Mechanical Engineering and Materials Science Program, Colorado School of Mines, Golden, Colorado 80401 (United States); Kodambaka, Suneel [Department of Materials Science and Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States)] [Department of Materials Science and Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States)

    2013-02-04

    Using density functional theory calculations, we show that the binding strength of a graphene monolayer on Pd(111) can vary between physisorption and chemisorption depending on its orientation. By studying the interfacial charge transfer, we have identified a specific four-atom carbon cluster that is responsible for the local bonding of graphene to Pd(111). The areal density of such clusters varies with the in-plane orientation of graphene, causing the binding energy to change accordingly. Similar investigations can also apply to other metal substrates and suggests that physical, chemical, and mechanical properties of graphene may be controlled by changing its orientation.

  15. Molecular dynamics investigation of the substrate binding mechanism in carboxylesterase

    SciTech Connect (OSTI)

    Chen, Qi; Luan, Zheng-Jiao; Cheng, Xiaolin; Xu, Jian-he

    2015-01-01

    A recombinant carboxylesterase, cloned from Pseudomonas putida and designated as rPPE, is capable of catalyzing the bioresolution of racemic 2-acetoxy-2-(2 -chlorophenyl)acetate (rac-AcO-CPA) with excellent (S)-enantioselectivity. Semi-rational design of the enzyme showed that the W187H variant could increase the activity by ~100-fold compared to the wild type (WT) enzyme. In this study, we performed all-atom molecular dynamics (MD) simulations of both apo-rPPE and rPPE in complex with (S)-AcO-CPA to gain insights into the origin of the increased catalysis in the W187H mutant. Our results show differential binding of (S)-AcO-CPA in the WT and W187H enzymes, especially the interactions of the substrate with the two active site residues Ser159 and His286. The replacement of Trp187 by His leads to considerable structural rearrangement in the active site of W187H. Unlike in the WT rPPE, the cap domain in the W187 mutant shows an open conformation in the simulations of both apo and substrate-bound enzymes. This open conformation exposes the catalytic triad to the solvent through a water accessible channel, which may facilitate the entry of the substrate and/or the exit of the product. Binding free energy calculations confirmed that the substrate binds more strongly in W187H than in WT. Based on these computational results, we further predicted that the mutations W187Y and D287G might also be able to increase the substrate binding, thus improve the enzyme s catalytic efficiency. Experimental binding and kinetic assays on W187Y and D287G show improved catalytic efficiency over WT, but not W187H. Contrary to our prediction, W187Y shows slightly decreased substrate binding coupled with a 100 fold increase in turn-over rate, while in D287G the substrate binding is 8 times stronger but with a slightly reduced turn-over rate. Our work provides important molecular-level insights into the binding of the (S)-AcO-CPA substrate to carboxylesterase rPPEs, which will help guide

  16. Molecular Dynamics Investigation of the Substrate Binding Mechanism in Carboxylesterase

    SciTech Connect (OSTI)

    Chen, Qi; Luan, Zheng-Jiao; Cheng, Xiaolin; Xu, Jian-He

    2015-02-25

    A recombinant carboxylesterase, cloned from Pseudomonas putida and designated as rPPE, is capable of catalyzing the bioresolution of racemic 2-acetoxy-2-(2 -chlorophenyl)acetate (rac-AcO-CPA) with excellent (S)-enantioselectivity. Semi-rational design of the enzyme showed that the W187H variant could increase the activity by ~100-fold compared to the wild type (WT) enzyme. In this study, we performed all-atom molecular dynamics (MD) simulations of both apo-rPPE and rPPE in complex with (S)-AcO-CPA to gain insights into the origin of the increased catalysis in the W187H mutant. Moreover, our results show differential binding of (S)-AcO-CPA in the WT and W187H enzymes, especially the interactions of the substrate with the two active site residues Ser159 and His286. The replacement of Trp187 by His leads to considerable structural rearrangement in the active site of W187H. Unlike in the WT rPPE, the cap domain in the W187 mutant shows an open conformation in the simulations of both apo and substrate-bound enzymes. This open conformation exposes the catalytic triad to the solvent through a water accessible channel, which may facilitate the entry of the substrate and/or the exit of the product. Binding free energy calculations confirmed that the substrate binds more strongly in W187H than in WT. Based on these computational results, furthermore, we predicted that the mutations W187Y and D287G might also be able to increase the substrate binding, thus improve the enzyme s catalytic efficiency. Experimental binding and kinetic assays on W187Y and D287G show improved catalytic efficiency over WT, but not W187H. Contrary to our prediction, W187Y shows slightly decreased substrate binding coupled with a 100 fold increase in turn-over rate, while in D287G the substrate binding is 8 times stronger but with a slightly reduced turn-over rate. Finally, our work provides important molecular-level insights into the binding of the (S)-AcO-CPA substrate to carboxylesterase r

  17. Molecular Dynamics Investigation of the Substrate Binding Mechanism in Carboxylesterase

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chen, Qi; Luan, Zheng-Jiao; Cheng, Xiaolin; Xu, Jian-He

    2015-02-25

    A recombinant carboxylesterase, cloned from Pseudomonas putida and designated as rPPE, is capable of catalyzing the bioresolution of racemic 2-acetoxy-2-(2 -chlorophenyl)acetate (rac-AcO-CPA) with excellent (S)-enantioselectivity. Semi-rational design of the enzyme showed that the W187H variant could increase the activity by ~100-fold compared to the wild type (WT) enzyme. In this study, we performed all-atom molecular dynamics (MD) simulations of both apo-rPPE and rPPE in complex with (S)-AcO-CPA to gain insights into the origin of the increased catalysis in the W187H mutant. Moreover, our results show differential binding of (S)-AcO-CPA in the WT and W187H enzymes, especially the interactions of themore » substrate with the two active site residues Ser159 and His286. The replacement of Trp187 by His leads to considerable structural rearrangement in the active site of W187H. Unlike in the WT rPPE, the cap domain in the W187 mutant shows an open conformation in the simulations of both apo and substrate-bound enzymes. This open conformation exposes the catalytic triad to the solvent through a water accessible channel, which may facilitate the entry of the substrate and/or the exit of the product. Binding free energy calculations confirmed that the substrate binds more strongly in W187H than in WT. Based on these computational results, furthermore, we predicted that the mutations W187Y and D287G might also be able to increase the substrate binding, thus improve the enzyme s catalytic efficiency. Experimental binding and kinetic assays on W187Y and D287G show improved catalytic efficiency over WT, but not W187H. Contrary to our prediction, W187Y shows slightly decreased substrate binding coupled with a 100 fold increase in turn-over rate, while in D287G the substrate binding is 8 times stronger but with a slightly reduced turn-over rate. Finally, our work provides important molecular-level insights into the binding of the (S)-AcO-CPA substrate to carboxylesterase r

  18. Stand-off transmission lines and method for making same

    DOE Patents [OSTI]

    Tuckerman, D.B.

    1991-05-21

    Standoff transmission lines in an integrated circuit structure are formed by etching away or removing the portion of the dielectric layer separating the microstrip metal lines and the ground plane from the regions that are not under the lines. The microstrip lines can be fabricated by a subtractive process of etching a metal layer, an additive process of direct laser writing fine lines followed by plating up the lines or a subtractive/additive process in which a trench is etched over a nucleation layer and the wire is electrolytically deposited. Microstrip lines supported on freestanding posts of dielectric material surrounded by air gaps are produced. The average dielectric constant between the lines and ground plane is reduced, resulting in higher characteristic impedance, less crosstalk between lines, increased signal propagation velocities, and reduced wafer stress. 16 figures.

  19. Stand-off transmission lines and method for making same

    DOE Patents [OSTI]

    Tuckerman, David B.

    1991-01-01

    Standoff transmission lines in an integrated circuit structure are formed by etching away or removing the portion of the dielectric layer separating the microstrip metal lines and the ground plane from the regions that are not under the lines. The microstrip lines can be fabricated by a subtractive process of etching a metal layer, an additive process of direct laser writing fine lines followed by plating up the lines or a subtractive/additive process in which a trench is etched over a nucleation layer and the wire is electrolytically deposited. Microstrip lines supported on freestanding posts of dielectric material surrounded by air gaps are produced. The average dielectric constant between the lines and ground plane is reduced, resulting in higher characteristic impedance, less crosstalk between lines, increased signal propagation velocities, and reduced wafer stress.

  20. A probabilistic approach to microRNA-target binding

    SciTech Connect (OSTI)

    Ogul, Hasan; Umu, Sinan U.; Bioinformatics Program, Informatics Institute, Middle East Technical University, Cankaya TR-06800, Ankara ; Tuncel, Y. Yener; Akkaya, Mahinur S.

    2011-09-16

    Highlights: {yields} A new probabilistic model is introduced for microRNA-target binding. {yields} The new model significantly outperforms RNAHybrid and miRTif. {yields} The experiments can unveil the effects of the type and directions of distinct base pairings. -- Abstract: Elucidation of microRNA activity is a crucial step in understanding gene regulation. One key problem in this effort is how to model the pairwise interactions of microRNAs with their targets. As this interaction is strongly mediated by their sequences, it is desired to set-up a probabilistic model to explain the binding preferences between a microRNA sequence and the sequence of a putative target. To this end, we introduce a new model of microRNA-target binding, which transforms an aligned duplex to a new sequence and defines the likelihood of this sequence using a Variable Length Markov Chain. It offers a complementary representation of microRNA-mRNA pairs for microRNA target prediction tools or other probabilistic frameworks of integrative gene regulation analysis. The performance of present model is evaluated by its ability to predict microRNA-target mRNA interaction given a mature microRNA sequence and a putative mRNA binding site. In regard to classification accuracy, it outperforms two recent methods based on thermodynamic stability and sequence complementarity. The experiments can also unveil the effects of base pairing types and non-seed region in duplex formation.

  1. Methods of detection using a cellulose binding domain fusion product

    DOE Patents [OSTI]

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc A.; Doi, Roy H.

    1999-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  2. Inhibition Of Call-Cell Binding By Kipid Assemblies

    DOE Patents [OSTI]

    Nagy, Jon O. , Bargatze, Robert F.

    2003-12-16

    This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.

  3. Inhibition of cell-cell binding by lipid assemblies

    DOE Patents [OSTI]

    Nagy, Jon O.; Bargatze, Robert F.

    2001-05-22

    This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.

  4. Structural basis for DNA binding by replication initiator Mcm10

    SciTech Connect (OSTI)

    Warren, Eric M.; Vaithiyalingam, Sivaraja; Haworth, Justin; Greer, Briana; Bielinsky, Anja-Katrin; Chazin, Walter J.; Eichman, Brandt F.

    2009-06-30

    Mcm10 is an essential eukaryotic DNA replication protein required for assembly and progression of the replication fork. The highly conserved internal domain (Mcm10-ID) has been shown to physically interact with single-stranded (ss) DNA, DNA polymerase alpha, and proliferating cell nuclear antigen (PCNA). The crystal structure of Xenopus laevis Mcm10-ID presented here reveals a DNA binding architecture composed of an oligonucleotide/oligosaccharide-fold followed in tandem by a variant and highly basic zinc finger. NMR chemical shift perturbation and mutational studies of DNA binding activity in vitro reveal how Mcm10 uses this unique surface to engage ssDNA. Corresponding mutations in Saccharomyces cerevisiae result in increased sensitivity to replication stress, demonstrating the functional importance of DNA binding by this region of Mcm10 to replication. In addition, mapping Mcm10 mutations known to disrupt PCNA, polymerase alpha, and DNA interactions onto the crystal structure provides insight into how Mcm10 might coordinate protein and DNA binding within the replisome.

  5. Workshop on gate valve pressure locking and thermal binding

    SciTech Connect (OSTI)

    Brown, E.J.

    1995-07-01

    The purpose of the Workshop on Gate Valve Pressure Locking and Thermal Binding was to discuss pressure locking and thermal binding issues that could lead to inoperable gate valves in both boiling water and pressurized water reactors. The goal was to foster exchange of information to develop the technical bases to understand the phenomena, identify the components that are susceptible, discuss actual events, discuss the safety significance, and illustrate known corrective actions that can prevent or limit the occurrence of pressure locking or thermal binding. The presentations were structured to cover U.S. Nuclear Regulatory Commission staff evaluation of operating experience and planned regulatory activity; industry discussions of specific events, including foreign experience, and efforts to determine causes and alleviate the affects; and valve vendor experience and recommended corrective action. The discussions indicated that identifying valves susceptible to pressure locking and thermal binding was a complex process involving knowledge of components, systems, and plant operations. The corrective action options are varied and straightforward.

  6. Methods of use of cellulose binding domain proteins

    DOE Patents [OSTI]

    Shoseyov, O.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.

    1997-09-23

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.

  7. Methods of detection using a cellulose binding domain fusion product

    DOE Patents [OSTI]

    Shoseyov, O.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.

    1999-01-05

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 34 figs.

  8. Modeling silver binding to gills of rainbow trout (Oncorhynchus mykiss)

    SciTech Connect (OSTI)

    Janes, N.; Playle, R.C.

    1995-11-01

    Rainbow trout (Oncorhynchus mykiss, 1--3 g) were exposed to {approximately} 1.0 {micro}M silver (Ag) ({approximately} 11 {micro}g {center_dot} L{sup {minus}1} Ag) for 2 to 3 h in synthetic soft water (Ca, Na {approximately} 300 {micro}M, pH 6.5--7.5) to which was added Ca, Na, H{sup +}, dissolved organic carbon (DOC), Cl, or thiosulfate (S{sub 2}O{sub 3}). Gills were extracted and gill Ag concentrations were measured using graphite-furnace atomic absorption spectrophotometry. The concentration of cations (Ca, Na, H{sup +}) and complexing agents (DOC, Cl, S{sub 2}O{sub 3}) needed to keep Ag off the gills were used to calculate conditional equilibrium binding constants (K) at the gills. Log K for Ag-gill binding was 10.0, with approximately 1.3 nmol Ag binding sites per fish. All experimentally determined log K values were entered into an aquatic chemistry equilibrium model, MINEQL{sup +}, to predict Ag binding at trout gills. For a series of natural waters, model-predicted gill Ag concentrations correlated well with observed gill Ag concentrations, with one exception, very hard city of Waterloo tapwater. This exception may indicate a kinetic constraint on the thermodynamic basis of the model.

  9. Methods of use of cellulose binding domain proteins

    DOE Patents [OSTI]

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc A.; Doi, Roy H.

    1997-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  10. SunLine Transit Agency | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technology Validation » SunLine Transit Agency SunLine Transit Agency SunLine Transit Agency logo SunLine Transit Agency provides public transit and community services to California's Coachella Valley. The service area is more than 1,100 square miles and includes nine member cities, as well as Riverside County. Over the years, SunLine has pursued an aggressive strategy for implementing clean technologies into its fleet. SunLine began by switching its fleet to compressed natural gas (CNG), then

  11. Forties oil line replacement overcomes sandwave challenge

    SciTech Connect (OSTI)

    Steel, W.J.M.; Imglis, R. )

    1991-03-06

    A major new 36-in., oil-export pipeline has been installed in the North Sea between the Forties field and Cruden Bay on the U.K. mainland. Designing and installing the line involved solving problems caused by sandwaves in the nearshore segment of the route. The Forties pipeline system covers offshore and land pipelines between the Forties field and the Firth of Forth tanker loading terminal and incorporates oil transportation, stabilization-gas separation, processing, and storage. The pipeline is used as part of an integrated oil and gas liquid gathering system from the central North Sea. Oil and gas liquids from other offshore fields are connected by subsea pipelines and riser to the Forties Charlie platform. Inspection of the existing 32-in. offshore pipeline had indicated signs of corrosion which would prevent the system from operating economically as future demands increased. In addition, when the line was commissioned in 1975, it was not envisioned that it would eventually carry crude from several other fields, which will come onstream this decade. The decision to lay a new 36-in. sealine reflects this need for increased capacity to ensure that the Forties pipeline system continues as a major carrier of oil and gas liquids well into the next century. Corrosion monitoring and inspection of the 32-in. line led to sections of the topside pipework being replaced in 1985 and the top section of the rise in 1987. The corrosion also resulted in the pipeline maximum allowable operating pressure (MAOP) being limited to 115 barg (1,668 psig) from 129 barg (1,871 psig).

  12. Fluid properties determine flow line blockage potential

    SciTech Connect (OSTI)

    Hunt, A.

    1996-07-15

    A thorough understanding of fluid properties helps in determining the potential of hydrates, paraffins, or asphaltenes to block subsea flow lines. Thermal, chemical, and mechanical methods are the main ways for preventing deposition. Already in both the North Sea and the Gulf of Mexico, blockages have led to significant losses in production and reserves recovery. This first article in a two-part series discusses thermal and chemical methods in overcoming fluid behavior problems caused by hydrate and other fluid constituents in subsea multiphase flow. The paper discusses subsea production, possible problems, nucleation, growth, deposition, preventing deposition, hydrate predictions, multiphase flow, and hydrate inhibition.

  13. A radial transmission line material measurement apparatus

    SciTech Connect (OSTI)

    Warne, L.K.; Moyer, R.D.; Koontz, T.E.; Morris, M.E.

    1993-05-01

    A radial transmission line material measurement sample apparatus (sample holder, offset short standards, measurement software, and instrumentation) is described which has been proposed, analyzed, designed, constructed, and tested. The purpose of the apparatus is to obtain accurate surface impedance measurements of lossy, possibly anisotropic, samples at low and intermediate frequencies (vhf and low uhf). The samples typically take the form of sections of the material coatings on conducting objects. Such measurements thus provide the key input data for predictive numerical scattering codes. Prediction of the sample surface impedance from the coaxial input impedance measurement is carried out by two techniques. The first is an analytical model for the coaxial-to-radial transmission line junction. The second is an empirical determination of the bilinear transformation model of the junction by the measurement of three full standards. The standards take the form of three offset shorts (and an additional lossy Salisbury load), which have also been constructed. The accuracy achievable with the device appears to be near one percent.

  14. On-line subsea multiphase flow measurement

    SciTech Connect (OSTI)

    High, G.; Frantzen, K.H.; Marshall, M.

    1995-12-31

    This paper describes the final detailed design, engineering, and installation phase of a Joint Industry Program to qualify a robust subsea multiphase flowmeter module for long-term installation on a North Sea manifold tie-in. Multiphase subsea production has become a common method of hydrocarbon recovery in all areas of offshore E and P. In the North Sea, many developments are subsea satellites with multiphase well-fluids being comingled prior to processing. The system described meets this challenge by offering a cost effective solution to real-time well monitoring as an alternative to the conventional test separator, removing the need for test lines and shutting in wells for testing. The multiphase instrument allows on-line well fluid analysis, and is also an important tool for reservoir management and field analysis, and provides a means of implementing field allocation metering thereby simplifying small marginal field developments. This project is one of the first subsea multiphase flowmeter installations engineered for long-term subsea service, and designed as an integrated component of the subsea production control system.

  15. Mitsui O S K Lines Ltd | Open Energy Information

    Open Energy Info (EERE)

    O S K Lines Ltd Jump to: navigation, search Name: Mitsui O.S.K. Lines Ltd Place: Tokyo, Japan Zip: 1058688 Sector: Services Product: A shipping company, with services including...

  16. EIS-0465: Mid-Atlantic Power Pathway Transmission Line Project...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5: Mid-Atlantic Power Pathway Transmission Line Project in Maryland and Delaware EIS-0465: Mid-Atlantic Power Pathway Transmission Line Project in Maryland and Delaware March 4, ...

  17. EIS-0507: Boardman-Hemingway Transmission Line, Oregon and Idaho...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    7: Boardman-Hemingway Transmission Line, Oregon and Idaho EIS-0507: Boardman-Hemingway Transmission Line, Oregon and Idaho Summary The Bureau of Land Management and the U.S. Forest ...

  18. Changes to the Transfer Line Collimation System for the High...

    Office of Scientific and Technical Information (OSTI)

    Changes to the Transfer Line Collimation System for the High-Luminosity LHC Beams Citation Details In-Document Search Title: Changes to the Transfer Line Collimation System for the ...

  19. EIS-0421: Big Eddy-Knight Transmission Line

    Broader source: Energy.gov [DOE]

    BPA is proposing to build a new 500 kilovolt (kV) transmission line in Wasco County, Oregon and Klickitat County, Washington and a new substation in Klickitat County. The new BPA transmission line...

  20. Microsoft Word - WIPP Water Line _2_ _2_ _2_

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Announces the Transfer of the WIPP Water Line to the City of Carlsbad CARLSBAD, N.M., June ... the DOE-owned Waste Isolation Pilot Plant (WIPP) water line to the city of Carlsbad. ...

  1. Secretary Chu Thanks Utility Staff and Line Workers For Their...

    Broader source: Energy.gov (indexed) [DOE]

    staff to the front lines to repair downed power lines and bring electricity back online. ... as they prepared to go out for the day to continue power restoration efforts in the state. ...

  2. Updated Web Tool Focuses on Bottom Line for Distributed Wind...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Updated Web Tool Focuses on Bottom Line for Distributed Wind Turbines Updated Web Tool Focuses on Bottom Line for Distributed Wind Turbines January 10, 2013 - 2:43pm Addthis This...

  3. To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 29, 2007 6:28 PM To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Larry, Regarding the planned line outage, scheduled for Feb. 20 through Mar...

  4. Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Docket No. EO-05-01. Regarding the planned line outage, scheduled for Feb. 20 through Mar. 6, ...

  5. Power Line Plan of Development Outline | Open Energy Information

    Open Energy Info (EERE)

    Line Plan of Development Outline Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- OtherOther: Power Line Plan of Development OutlineLegal...

  6. File:08HIATransmissionLineApproval.pdf | Open Energy Information

    Open Energy Info (EERE)

    8HIATransmissionLineApproval.pdf Jump to: navigation, search File File history File usage Metadata File:08HIATransmissionLineApproval.pdf Size of this preview: 463 599 pixels....

  7. In-line stirling energy system (Patent) | DOEPatents

    Office of Scientific and Technical Information (OSTI)

    In-line stirling energy system Title: In-line stirling energy system A high efficiency generator is provided using a Stirling engine to amplify an acoustic wave by heating the gas ...

  8. Plains & Eastern Clean Line Project Proposal for New or Upgraded...

    Broader source: Energy.gov (indexed) [DOE]

    Clean Line Project Proposal for New or Upgraded Transmission Line Projects Under Section 1222 of the Energy Policy Act of 2005 (July 2010) PDF icon Update to Plains & Eastern Clean ...

  9. Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-[alpha

    SciTech Connect (OSTI)

    Carter, Percy H.; Scherle, Peggy A.; Muckelbauer, Jodi K.; Voss, Matthew E.; Liu, Rui-qin; Thompson III, Lorin A.; Xu, Meizhong; Lo, Yvonne C.; Li, Zhong; Strzemienski, Paul; Yang, Gengjie; Falahatpishen, Nikoo; Farrow, Neil A.; Tebben, Andrew J.; Underwood, Denis; Trzaskos, James M.; Friedman, Steven M.; Newton, Robert C.; Decicco, Carl P.

    2010-03-05

    The binding of tumor necrosis factor alpha (TNF-{alpha}) to the type-1 TNF receptor (TNFRc1) plays an important role in inflammation. Despite the clinical success of biologics (antibodies, soluble receptors) for treating TNF-based autoimmune conditions, no potent small molecule antagonists have been developed. Our screening of chemical libraries revealed that N-alkyl 5-arylidene-2-thioxo-1,3-thiazolidin-4-ones were antagonists of this protein-protein interaction. After chemical optimization, we discovered IW927, which potently disrupted the binding of TNF-{alpha} to TNFRc1 (IC{sub 50} = 50 nM) and also blocked TNF-stimulated phosphorylation of I{kappa}-B in Ramos cells (IC{sub 50} = 600 nM). This compound did not bind detectably to the related cytokine receptors TNFRc2 or CD40, and did not display any cytotoxicity at concentrations as high as 100 {micro}M. Detailed evaluation of this and related molecules revealed that compounds in this class are 'photochemically enhanced' inhibitors, in that they bind reversibly to the TNFRc1 with weak affinity (ca. 40-100 mM) and then covalently modify the receptor via a photochemical reaction. We obtained a crystal structure of IV703 (a close analog of IW927) bound to the TNFRc1. This structure clearly revealed that one of the aromatic rings of the inhibitor was covalently linked to the receptor through the main-chain nitrogen of Ala-62, a residue that has already been implicated in the binding of TNF-{alpha} to the TNFRc1. When combined with the fact that our inhibitors are reversible binders in light-excluded conditions, the results of the crystallography provide the basis for the rational design of nonphotoreactive inhibitors of the TNF-{alpha}-TNFRc1 interaction.

  10. SSP/Dashboard Open-line Help Call | Department of Energy

    Energy Savers [EERE]

    line Help Call SSP/Dashboard Open-line Help Call September 20

  11. Advance Funding and Development Agreement: Plains & Eastern Clean Line

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Project (September 20, 2012) | Department of Energy Advance Funding and Development Agreement: Plains & Eastern Clean Line Transmission Project (September 20, 2012) Advance Funding and Development Agreement: Plains & Eastern Clean Line Transmission Project (September 20, 2012) Advance Funding and Development Agreement: Plains & Eastern Clean Line Transmission Project (September 20, 2012) (654.41 KB) More Documents & Publications Plains and Eastern Clean Line

  12. Federal Line Management Oversight of Department of Energy Nuclear

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Facilities | Department of Energy Federal Line Management Oversight of Department of Energy Nuclear Facilities Federal Line Management Oversight of Department of Energy Nuclear Facilities This Guide provides U.S. Department of Energy (DOE) line management organizations with guidance that may be useful to them in effectively and efficiently implementing the requirements of DOE O 226.1B, Implementation of Department of Energy Oversight Policy, dated April 25, 2011, as applied to Federal line

  13. Appendix B: Rules and Directives Applicable to Nuclear Facilities Line

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Management Oversight | Department of Energy Appendix B: Rules and Directives Applicable to Nuclear Facilities Line Management Oversight Appendix B: Rules and Directives Applicable to Nuclear Facilities Line Management Oversight Appendix B to DOE G 226.1-2A "Federal Line Management Oversight of Department of Energy Nuclear Facilities". Consists of a list of rules and directives that are applicable to nuclear facilities line management oversight. Appendix B: Rules and Directives

  14. Insulate Steam Distribution and Condensate Return Lines | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Insulate Steam Distribution and Condensate Return Lines Insulate Steam Distribution and Condensate Return Lines This tip sheet on insulating steam distribution and condensate return lines provides how-to advice for improving industrial steam systems using low-cost, proven practices and technologies. STEAM TIP SHEET #2 Insulate Steam Distribution and Condensate Return Lines (January 2012) (385.81 KB) More Documents & Publications Use a Vent Condenser to Recover Flash Steam Energy

  15. On-line tritium production monitor

    DOE Patents [OSTI]

    Mihalczo, J.T.

    1993-11-23

    A scintillation optical fiber system for the on-line monitoring of nuclear reactions in an event-by-event manner is described. In the measurement of tritium production one or more optical fibers are coated with enriched {sup 6}Li and connected to standard scintillation counter circuitry. A neutron generated {sup 6}Li(n)T reaction occurs in the coated surface of {sup 6}Li-coated fiber to produce energetic alpha and triton particles one of which enters the optical fiber and scintillates light through the fiber to the counting circuit. The coated optical fibers can be provided with position sensitivity by placing a mirror at the free end of the fibers or by using pulse counting circuits at both ends of the fibers. 5 figures.

  16. Atomic line emission analyzer for hydrogen isotopes

    DOE Patents [OSTI]

    Kronberg, J.W.

    1993-03-30

    Apparatus for isotopic analysis of hydrogen comprises a low pressure chamber into which a sample of hydrogen is introduced and then exposed to an electrical discharge to excite the electrons of the hydrogen atoms to higher energy states and thereby cause the emission of light on the return to lower energy states, a Fresnel prism made at least in part of a material anomalously dispersive to the wavelengths of interest for dispersing the emitted light, and a photodiode array for receiving the dispersed light. The light emitted by the sample is filtered to pass only the desired wavelengths, such as one of the lines of the Balmer series for hydrogen, the wavelengths of which differ slightly from one isotope to another. The output of the photodiode array is processed to determine the relative amounts of each isotope present in the sample. Additionally, the sample itself may be recovered using a metal hydride.

  17. Dispersion-free radial transmission lines

    DOE Patents [OSTI]

    Caporaso, George J.; Nelson, Scott D.

    2011-04-12

    A dispersion-free radial transmission line ("DFRTL") preferably for linear accelerators, having two plane conductors each with a central hole, and an electromagnetically permeable material ("EPM") between the two conductors and surrounding a channel connecting the two holes. At least one of the material parameters of relative magnetic permeability, relative dielectric permittivity, and axial width of the EPM is varied as a function of radius, so that the characteristic impedance of the DFRTL is held substantially constant, and pulse transmission therethrough is substantially dispersion-free. Preferably, the EPM is divided into concentric radial sections, with the varied material parameters held constant in each respective section but stepwise varied between sections as a step function of the radius. The radial widths of the concentric sections are selected so that pulse traversal time across each section is the same, and the varied material parameters of the concentric sections are selected to minimize traversal error.

  18. Second Line of Defense Spares Program Assessment

    SciTech Connect (OSTI)

    Henderson, Dale L.; Muller, George; Mercier, Theresa M.; Brigantic, Robert T.; Perkins, Casey J.; Cooley, Scott K.

    2012-11-20

    The Office of the Second Line of Defense (SLD) is part of the Department of Energy‘s (DOE) National Nuclear Security Administration (NNSA). The SLD Program accomplishes its critical global security mission by forming cooperative relationships with partner countries to install passive radiation detection systems that augment traditional inspection and law enforcement measures by alerting border officials to the presence of special nuclear or other radiological materials in cross-border traffic. An important tenet of the program is to work collaboratively with these countries to establish the necessary processes, procedures, infrastructure and conditions that will enable them to fully assume the financial and technical responsibilities for operating the equipment. As the number of operational deployments grows, the SLD Program faces an increasingly complex logistics process to promote the timely and efficient supply of spare parts.

  19. Atomic line emission analyzer for hydrogen isotopes

    DOE Patents [OSTI]

    Kronberg, James W.

    1993-01-01

    Apparatus for isotopic analysis of hydrogen comprises a low pressure chamber into which a sample of hydrogen is introduced and then exposed to an electrical discharge to excite the electrons of the hydrogen atoms to higher energy states and thereby cause the emission of light on the return to lower energy states, a Fresnel prism made at least in part of a material anomalously dispersive to the wavelengths of interest for dispersing the emitted light, and a photodiode array for receiving the dispersed light. The light emitted by the sample is filtered to pass only the desired wavelengths, such as one of the lines of the Balmer series for hydrogen, the wavelengths of which differ slightly from one isotope to another. The output of the photodiode array is processed to determine the relative amounts of each isotope present in the sample. Additionally, the sample itself may be recovered using a metal hydride.

  20. On-line tritium production monitor

    DOE Patents [OSTI]

    Mihalczo, John T.

    1993-01-01

    A scintillation optical fiber system for the on-line monitoring of nuclear reactions in an event-by-event manner is described. In the measurement of tritium production one or more optical fibers are coated with enriched .sup.6 Li and connected to standard scintillation counter circuitry. A neutron generated .sup.6 Li(n )T reaction occurs in the coated surface of .sup.6 Li-coated fiber to produce energetic alpha and triton particles one of which enters the optical fiber and scintillates light through the fiber to the counting circuit. The coated optical fibers can be provided with position sensitivity by placing a mirror at the free end of the fibers or by using pulse counting circuits at both ends of the fibers.

  1. Atomic line emission analyzer for hydrogen isotopes

    DOE Patents [OSTI]

    Kronberg, J.W.

    1991-05-08

    Apparatus for isotopic analysis of hydrogen comprises a low pressure chamber into which a sample of hydrogen is introduced and then exposed to an electrical discharge to excite the electrons of the hydrogen atoms to higher energy states and thereby cause the emission of light on the return to lower energy states, a Fresnel prism made at least in part of a material anomalously dispersive to the wavelengths of interest for dispersing the emitted light, and a photodiode array for receiving the dispersed light. The light emitted by the sample is filtered to pass only the desired wavelengths, such as one of the lines of the Balmer series for hydrogen, the wavelengths of which differ slightly from one isotope to another. The output of the photodiode array is processed to determine the relative amounts of each isotope present in the sample. Additionally, the sample itself may be recovered using, a metal hydride.

  2. Spectral line broadening in magnetized black holes

    SciTech Connect (OSTI)

    Frolov, Valeri P.; Shoom, Andrey A.; Tzounis, Christos E-mail: ashoom@ualberta.ca

    2014-07-01

    We consider weakly magnetized non-rotating black holes. In the presence of a regular magnetic field the motion of charged particles in the vicinity of a black hole is modified. As a result, the position of the innermost stable circular orbit (ISCO) becomes closer to the horizon. When the Lorentz force is repulsive (directed from the black hole) the ISCO radius can reach the gravitational radius. In the process of accretion charged particles (ions) of the accreting matter can be accumulated near their ISCO, while neutral particles fall down to the black hole after they reach 6M radius. The sharp spectral line Fe α, emitted by iron ions at such orbits, is broadened when the emission is registered by a distant observer. In this paper we study this broadening effect and discuss how one can extract information concerning the strength of the magnetic field from the observed spectrum.

  3. On-line process control monitoring system

    DOE Patents [OSTI]

    O'Rourke, Patrick E.; Van Hare, David R.; Prather, William S.

    1992-01-01

    An on-line, fiber-optic based apparatus for monitoring the concentration of a chemical substance at a plurality of locations in a chemical processing system comprises a plurality of probes, each of which is at a different location in the system, a light source, optic fibers for carrying light to and from the probes, a multiplexer for switching light from the source from one probe to the next in series, a diode array spectrophotometer for producing a spectrum from the light received from the probes, and a computer programmed to analyze the spectra so produced. The probes allow the light to pass through the chemical substance so that a portion of the light is absorbed before being returned to the multiplexer. A standard and a reference cell are included for data validation and error checking.

  4. Accurate nuclear radii and binding energies from a chiral interaction

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ekstrom, Jan A.; Jansen, G. R.; Wendt, Kyle A.; Hagen, Gaute; Papenbrock, Thomas F.; Carlsson, Boris; Forssen, Christian; Hjorth-Jensen, M.; Navratil, Petr; Nazarewicz, Witold

    2015-05-01

    With the goal of developing predictive ab initio capability for light and medium-mass nuclei, two-nucleon and three-nucleon forces from chiral effective field theory are optimized simultaneously to low-energy nucleon-nucleon scattering data, as well as binding energies and radii of few-nucleon systems and selected isotopes of carbon and oxygen. Coupled-cluster calculations based on this interaction, named NNLOsat, yield accurate binding energies and radii of nuclei up to 40Ca, and are consistent with the empirical saturation point of symmetric nuclear matter. In addition, the low-lying collective Jπ=3- states in 16O and 40Ca are described accurately, while spectra for selected p- and sd-shellmore » nuclei are in reasonable agreement with experiment.« less

  5. Accurate nuclear radii and binding energies from a chiral interaction

    SciTech Connect (OSTI)

    Ekstrom, Jan A.; Jansen, G. R.; Wendt, Kyle A.; Hagen, Gaute; Papenbrock, Thomas F.; Carlsson, Boris; Forssen, Christian; Hjorth-Jensen, M.; Navratil, Petr; Nazarewicz, Witold

    2015-05-01

    With the goal of developing predictive ab initio capability for light and medium-mass nuclei, two-nucleon and three-nucleon forces from chiral effective field theory are optimized simultaneously to low-energy nucleon-nucleon scattering data, as well as binding energies and radii of few-nucleon systems and selected isotopes of carbon and oxygen. Coupled-cluster calculations based on this interaction, named NNLOsat, yield accurate binding energies and radii of nuclei up to 40Ca, and are consistent with the empirical saturation point of symmetric nuclear matter. In addition, the low-lying collective Jπ=3− states in 16O and 40Ca are described accurately, while spectra for selected p- and sd-shell nuclei are in reasonable agreement with experiment.

  6. Paul D. Boyer, Adenosine Triphosphate (ATP), and the Binding Change

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mechanism Paul D. Boyer, Adenosine Triphosphate (ATP), and the Binding Change Mechanism Resources with Additional Information Paul D. Boyer Courtesy of UCLA 'For Paul Boyer, the Nobel Prize was "an unexpected pleasure." It had been 20 years since he formulated a hypothesis to describe what he calls "the most prominent chemical reaction in the whole world." It is the process by which molecules produce ATP (adenosine triphosphate), thereby transmuting light, air, water and

  7. Binding Behavior of Dopamine Transporter Key to Understanding Chemical

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Print Most people have heard of adrenaline, the chemical that causes the "fight or flight" reaction in humans. Most people have also heard of the chemical substances cocaine and methamphetamine, which also elicit a particular (perhaps desired) human response. What most people do not know is that the same receptors in the human brain recognize the natural, or

  8. Binding Behavior of Dopamine Transporter Key to Understanding Chemical

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Print Most people have heard of adrenaline, the chemical that causes the "fight or flight" reaction in humans. Most people have also heard of the chemical substances cocaine and methamphetamine, which also elicit a particular (perhaps desired) human response. What most people do not know is that the same receptors in the human brain recognize the natural, or

  9. Binding Behavior of Dopamine Transporter Key to Understanding Chemical

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Print Most people have heard of adrenaline, the chemical that causes the "fight or flight" reaction in humans. Most people have also heard of the chemical substances cocaine and methamphetamine, which also elicit a particular (perhaps desired) human response. What most people do not know is that the same receptors in the human brain recognize the natural, or

  10. Characterization of Selective Binding of Alkali Cations with Carboxylate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterization of Selective Binding of Alkali Cations with Carboxylate Print During its lifetime, a cell spends a considerable fraction of its energy pumping sodium and calcium out and potassium in. This balancing process is similar to that found in the coils of the DNA double helix, where specific ions nestle and help stabilize this macromolecule. These are only two examples of selective ion interactions in biology; there are many others also vital to life. The existence of these interactions

  11. Characterization of Selective Binding of Alkali Cations with Carboxylate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterization of Selective Binding of Alkali Cations with Carboxylate Print During its lifetime, a cell spends a considerable fraction of its energy pumping sodium and calcium out and potassium in. This balancing process is similar to that found in the coils of the DNA double helix, where specific ions nestle and help stabilize this macromolecule. These are only two examples of selective ion interactions in biology; there are many others also vital to life. The existence of these interactions

  12. Characterization of Selective Binding of Alkali Cations with Carboxylate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterization of Selective Binding of Alkali Cations with Carboxylate Print During its lifetime, a cell spends a considerable fraction of its energy pumping sodium and calcium out and potassium in. This balancing process is similar to that found in the coils of the DNA double helix, where specific ions nestle and help stabilize this macromolecule. These are only two examples of selective ion interactions in biology; there are many others also vital to life. The existence of these interactions

  13. High molecular weight polysaccharide that binds and inhibits virus

    DOE Patents [OSTI]

    Konowalchuk, Thomas W

    2014-01-14

    This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods on inhibiting viral infectivity and/or pathogenicity, as well as immunogenic compositions. The invention further methods of inhibiting the growth of cancer cells and of ameliorating a symptom of aging. Additionally, the invention provides methods of detecting and/or quantifying and/or isolating viruses.

  14. Reversible Acid Gas Capture Using CO2-Binding Organic Liquids

    SciTech Connect (OSTI)

    Heldebrant, David J.; Koech, Phillip K.; Yonker, Clement R.; Rainbolt, James E.; Zheng, Feng

    2010-08-31

    Acid gas scrubbing technology is predominantly aqueous alkanolamine based. Of the acid gases, CO2, H2S and SO2 have been shown to be reversible, however there are serious disadvantages with corrosion and high regeneration costs. The primary scrubbing system composed of monoethanolamine is limited to 30% by weight because of the highly corrosive solution. This gravimetric limitation limits the CO2 volumetric (?108 g/L) and gravimetric capacity (?7 wt%) of the system. Furthermore the scrubbing system has a large energy penalty from pumping and heating the excess water required to dissolve the MEA bicarbonate salt. Considering the high specific heat of water (4 j/g-1K-1), low capacities and the high corrosion we set out to design a fully organic solvent that can chemically bind all acid gases i.e. CO2 as reversible alkylcarbonate ionic liquids or analogues thereof. Having a liquid acid gas carrier improves process economics because there is no need for excess solvent to pump and to heat. We have demonstrated illustrated in Figure 1, that CO2-binding organic liquids (CO2BOLs) have a high CO2 solubility paired with a much lower specific heat (<1.5 J/g-1K-1) than aqueous systems. CO2BOLs are a subsection of a larger class of materials known as Binding Organic Liquids (BOLs). Our BOLs have been shown to reversibly bind and release COS, CS2, and SO2, which we denote COSBOLS, CS2BOLs and SO2BOLs. Our BOLs are highly tunable and can be designed for post or pre-combustion gas capture. The design and testing of the next generation zwitterionic CO2BOLs and SO2BOLs are presented.

  15. Characterization of Selective Binding of Alkali Cations with Carboxylate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterization of Selective Binding of Alkali Cations with Carboxylate Print During its lifetime, a cell spends a considerable fraction of its energy pumping sodium and calcium out and potassium in. This balancing process is similar to that found in the coils of the DNA double helix, where specific ions nestle and help stabilize this macromolecule. These are only two examples of selective ion interactions in biology; there are many others also vital to life. The existence of these interactions

  16. Characterization of Selective Binding of Alkali Cations with Carboxylate

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Characterization of Selective Binding of Alkali Cations with Carboxylate Print During its lifetime, a cell spends a considerable fraction of its energy pumping sodium and calcium out and potassium in. This balancing process is similar to that found in the coils of the DNA double helix, where specific ions nestle and help stabilize this macromolecule. These are only two examples of selective ion interactions in biology; there are many others also vital to life. The existence of these interactions

  17. DNA-Binding Mechanism in Prokaryotic Partition Complex Formation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DNA-Binding Mechanism in Prokaryotic Partition Complex Formation Print The faithful inheritance of genetic information, essential for all organisms, requires accurate movement and positioning of replicated DNA to daughter cells during cell division. In cells without distinct nuclei (prokaryotes), this process, called partition or segregation, is mediated by par systems. The prototype system of prokaryotic partition is the Escherichia coli P1 plasmid par system, which consists of a centromere

  18. Thermodynamics of Binding Biomass to Cellulases for Renewable Fuel |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Argonne Leadership Computing Facility Thermodynamics of Binding Biomass to Cellulases for Renewable Fuel PI Name: Michael Crowley PI Email: michael.crowley@nrel.gov Institution: National Renewable Energy Laboratory Allocation Program: INCITE Allocation Hours at ALCF: 70 Million Year: 2013 Research Domain: Energy Technologies The U.S. Department of Energy (DOE) has stipulated that 30% of the gasoline demand be displaced by renewable transportation fuels from non-food feedstock by 2030. The

  19. Binding Behavior of Dopamine Transporter Key to Understanding Chemical

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reactions in the Brain Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain Print Most people have heard of adrenaline, the chemical that causes the "fight or flight" reaction in humans. Most people have also heard of the chemical substances cocaine and methamphetamine, which also elicit a particular (perhaps desired) human response. What most people do not know is that the same receptors in the human brain recognize the natural, or

  20. Gold Binding by Native and Chemically Modified Hops Biomasses

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    López, M. Laura; Gardea-Torresdey, J. L.; Peralta-Videa, J. R.; de la Rosa, G.; Armendáriz, V.; Herrera, I.; Troiani, H.; Henning, J.

    2005-01-01

    Heavy metals from mining, smelting operations and other industrial processing facilities pollute wastewaters worldwide. Extraction of metals from industrial effluents has been widely studied due to the economic advantages and the relative ease of technical implementation. Consequently, the search for new and improved methodologies for the recovery of gold has increased. In this particular research, the use of cone hops biomass ( Humulus lupulus ) was investigated as a new option for gold recovery. The results showed that the gold binding to native hops biomass was pH dependent from pH 2 to pH 6, with a maximum percentage bindingmore » at pH 3. Time dependency studies demonstrated that Au(III) binding to native and modified cone hops biomasses was found to be time independent at pH 2 while at pH 5, it was time dependent. Capacity experiments demonstrated that at pH 2, esterified hops biomass bound 33.4 mg Au/g of biomass, while native and hydrolyzed hops biomasses bound 28.2 and 12.0 mg Au/g of biomass, respectively. However, at pH 5 the binding capacities were 38.9, 37.8 and 11.4 mg of Au per gram of native, esterified and hydrolyzed hops biomasses, respectively.« less

  1. Method for bonding a transmission line to a downhole tool

    DOE Patents [OSTI]

    Hall, David R.; Fox, Joe

    2007-11-06

    An apparatus for bonding a transmission line to the central bore of a downhole tool includes a pre-formed interface for bonding a transmission line to the inside diameter of a downhole tool. The pre-formed interface includes a first surface that substantially conforms to the outside contour of a transmission line and a second surface that substantially conforms to the inside diameter of a downhole tool. In another aspect of the invention, a method for bonding a transmission line to the inside diameter of a downhole tool includes positioning a transmission line near the inside wall of a downhole tool and placing a mold near the transmission line and the inside wall. The method further includes injecting a bonding material into the mold and curing the bonding material such that the bonding material bonds the transmission line to the inside wall.

  2. V-058: Microsoft Internet Explorer CDwnBindInfo Object Reuse...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8: Microsoft Internet Explorer CDwnBindInfo Object Reuse Flaw Lets Remote Users Execute Arbitrary Code V-058: Microsoft Internet Explorer CDwnBindInfo Object Reuse Flaw Lets Remote...

  3. Plasticity of the Quinone-binding Site of the Complex II Homolog...

    Office of Scientific and Technical Information (OSTI)

    Plasticity of the Quinone-binding Site of the Complex II Homolog Quinol:Fumarate Reductase Citation Details In-Document Search Title: Plasticity of the Quinone-binding Site of the...

  4. Discovery of a new ATP-binding motif involved in peptidic azoline...

    Office of Scientific and Technical Information (OSTI)

    Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis Citation Details In-Document Search Title: Discovery of a new ATP-binding motif involved in peptidic ...

  5. Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

    SciTech Connect (OSTI)

    Yang, Jingsong; Campobasso, Nino; Biju, Mangatt P.; Fisher, Kelly; Pan, Xiao-Qing; Cottom, Josh; Galbraith, Sarah; Ho, Thau; Zhang, Hong; Hong, Xuan; Ward, Paris; Hofmann, Glenn; Siegfried, Brett; Zappacosta, Francesca; Washio, Yoshiaki; Cao, Ping; Qu, Junya; Bertrand, Sophie; Wang, Da-Yuan; Head, Martha S.; Li, Hu; Moores, Sheri; Lai, Zhihong; Johanson, Kyung; Burton, George; Erickson-Miller, Connie; Simpson, Graham; Tummino, Peter; Copeland, Robert A.; Oliff, Allen

    2014-10-02

    c-Abl kinase activity is regulated by a unique mechanism involving the formation of an autoinhibited conformation in which the N-terminal myristoyl group binds intramolecularly to the myristoyl binding site on the kinase domain and induces the bending of the {alpha}I helix that creates a docking surface for the SH2 domain. Here, we report a small-molecule c-Abl activator, DPH, that displays potent enzymatic and cellular activity in stimulating c-Abl activation. Structural analyses indicate that DPH binds to the myristoyl binding site and prevents the formation of the bent conformation of the {alpha}I helix through steric hindrance, a mode of action distinct from the previously identified allosteric c-Abl inhibitor, GNF-2, that also binds to the myristoyl binding site. DPH represents the first cell-permeable, small-molecule tool compound for c-Abl activation.

  6. Two-photon Absorption In Quantum Dots,quantum Dashes And Related Materials

    SciTech Connect (OSTI)

    Jain, Ravinder

    2009-08-31

    We have proposed the use of USQDs for various deep-tissue biological imaging applications, notably wavelength-multiplexed multicolor imaging and intra-nuclear studies such as those involving cell apoptosis, and have studied the issue of maximizing two-photon absorption-induced fluorescence (TPAF) signals from CdSe/ZnS USQDs to be used for this application. In particular, using 2 nm USQDs, we have shown that the TPAF signal at 780 nm is ~ 8 times that at 850 nm and 68 times that at 900 nm, two wavelengths that have been used in previous studies using CdSe/ZnS SQDs for deep-tissue imaging of biological studies via TPAF .

  7. Demonstration of Datacenter Automation Software and Hardware (DASH) at the California Franchise Tax Board

    SciTech Connect (OSTI)

    Bell, Geoffrey C.; Federspiel, Clifford

    2009-12-18

    Control software and wireless sensors designed for closed-loop, monitoring and control of IT equipment's inlet air temperatures in datacenters were evaluated and tested while other datacenter cooling best practices were implemented. The controls software and hardware along with each best practice were installed sequentially and evaluated using a measurement and verification procedure between each measure. The results show that the overall project eliminates 475,239 kWh per year, which is 21.3percent of the baseline energy consumption of the data center. The total project, including the best practices will save $42,772 per year and cost $134,057 yielding a simple payback of 3.1 years. However, the control system alone eliminates 59.6percent of the baseline energy used to move air in the datacenter and 13.6percent of the baseline cooling energy, which is 15.2percent of the baseline energy consumption (see Project Approach, Task 1, below, for additional information) while keeping temperatures substantially within the limits recommended by ASHRAE. Savings attributed to the control system are $30,564 per year with a cost $56,824 for a simple payback of 1.9 years.

  8. Computational Investigation of Glycosylation Effects on a Family 1 Carbohydrate-Binding Module

    SciTech Connect (OSTI)

    Taylor, C. B.; Talib, M. F.; McCabe, C.; Bu, L.; Adney, W. S.; Himmel, M. E.; Crowley, M. F.; Beckham, G. T.

    2012-01-27

    Carbohydrate-binding modules (CBMs) are ubiquitous components of glycoside hydrolases, which degrade polysaccharides in nature. CBMs target specific polysaccharides, and CBM binding affinity to cellulose is known to be proportional to cellulase activity, such that increasing binding affinity is an important component of performance improvement. To ascertain the impact of protein and glycan engineering on CBM binding, we use molecular simulation to quantify cellulose binding of a natively glycosylated Family 1 CBM. To validate our approach, we first examine aromatic-carbohydrate interactions on binding, and our predictions are consistent with previous experiments, showing that a tyrosine to tryptophan mutation yields a 2-fold improvement in binding affinity. We then demonstrate that enhanced binding of 3-6-fold over a nonglycosylated CBM is achieved by the addition of a single, native mannose or a mannose dimer, respectively, which has not been considered previously. Furthermore, we show that the addition of a single, artificial glycan on the anterior of the CBM, with the native, posterior glycans also present, can have a dramatic impact on binding affinity in our model, increasing it up to 140-fold relative to the nonglycosylated CBM. These results suggest new directions in protein engineering, in that modifying glycosylation patterns via heterologous expression, manipulation of culture conditions, or introduction of artificial glycosylation sites, can alter CBM binding affinity to carbohydrates and may thus be a general strategy to enhance cellulase performance. Our results also suggest that CBM binding studies should consider the effects of glycosylation on binding and function.

  9. Pipe line companies to install 14,766 miles of lines in 1994

    SciTech Connect (OSTI)

    Ives, G. Jr.

    1994-01-01

    This paper reviews the historical and projected pipeline construction activities in the US and around the world. It gives mileage values for all types of oil and gas transmission lines, both on and offshore. Tables provides information on the diameters of these pipelines and information on compressor stations planned and constructed. Known major construction projects are listed by company name with a brief description of the proposed project.

  10. Second Line of Defense Spares Program

    SciTech Connect (OSTI)

    Henderson, Dale L.; Holmes, Aimee E.; Muller, George; Mercier, Theresa M.; Brigantic, Robert T.; Perkins, Casey J.; Cooley, Scott K.; Thorsen, Darlene E.

    2012-11-20

    During Fiscal Year 2012, a team from the Pacific Northwest National Laboratory (PNNL) conducted an assessment and analysis of the Second Line of Defense (SLD) Sustainability spare parts program. Spare parts management touches many aspects of the SLD Sustainability Program including contracting and integration of Local Maintenance Providers (LMP), equipment vendors, analyses and metrics on program performance, system state of health, and maintenance practices. Standardized spares management will provide better data for decisions during site transition phase and will facilitate transition to host country sustainability ownership. The effort was coordinated with related SLD Sustainability Program initiatives, including a configuration items baselining initiative, a metrics initiative, and a maintenance initiative. The spares study has also led to pilot programs for sourcing alternatives that include regional intermediate inventories and partnering agreements that leverage existing supply chains. Many partners from the SLD Sustainability program contributed to and were consulted in the course of the study. This document provides a description of the findings, recommendations, and implemented solutions that have resulted from the study.

  11. Ecuador plans expanded crude-oil line

    SciTech Connect (OSTI)

    Boschat, J.; Sabathier, J. )

    1995-01-23

    Ecuador plans to increase throughput of the 309 mile, 20 and 26-in. Trans Ecuadorian pipeline that moves crude oil from the Oriente in the Amazon basin to the Pacific coast for refining in local refineries and export. Increasing crude-oil production is driving the expansion. In investment, it is the largest pipeline project in the country in more than 20 years. In August 1992, Petro-ecuador, the Ecuadorian state company in charge of petroleum, hired the French petroleum consulting firm Beicip-Franlab to carry out the basic engineering and preparation of the technical tender documents for increasing the pipeline's throughput. The revamped Trans Ecuadorian pipeline, together with the Triunfo Nuevo-Condijua pipeline, will form the new Trans Ecuadorian pipeline system. This means that they will be integrated into a single system controlled and monitored from a main dispatching center in Guajalo near Quito which is now Petroecuador's maintenance center for the existing pipeline. As there is no supervisory control and data acquisition (scada) system now on the Trans Ecuadorian pipeline, scada will be built along with a new telecommunication network covering the entire new Trans Ecuadorian pipeline system. Also, to comply with the most modern requirements in terms of environmental protection, especially in a country subject to seismic activity, a leak-detection system will be implemented on all lines.

  12. Contingency Analysis of Cascading Line Outage Events

    SciTech Connect (OSTI)

    Thomas L Baldwin; Magdy S Tawfik; Miles McQueen

    2011-03-01

    As the US power systems continue to increase in size and complexity, including the growth of smart grids, larger blackouts due to cascading outages become more likely. Grid congestion is often associated with a cascading collapse leading to a major blackout. Such a collapse is characterized by a self-sustaining sequence of line outages followed by a topology breakup of the network. This paper addresses the implementation and testing of a process for N-k contingency analysis and sequential cascading outage simulation in order to identify potential cascading modes. A modeling approach described in this paper offers a unique capability to identify initiating events that may lead to cascading outages. It predicts the development of cascading events by identifying and visualizing potential cascading tiers. The proposed approach was implemented using a 328-bus simplified SERC power system network. The results of the study indicate that initiating events and possible cascading chains may be identified, ranked and visualized. This approach may be used to improve the reliability of a transmission grid and reduce its vulnerability to cascading outages.

  13. Boron-Lined Neutron Detector Measurements

    SciTech Connect (OSTI)

    Lintereur, Azaree T.; Kouzes, Richard T.; Ely, James H.; Erikson, Luke E.; Siciliano, Edward R.; Woodring, Mitchell L.

    2010-03-07

    PNNL-18938 Revision Radiation portal monitors used for interdiction of illicit materials at borders include highly sensitive neutron detection systems. The main reason for having neutron detection capability is to detect fission neutrons from plutonium. The currently deployed radiation portal monitors (RPMs) from Ludlum and Science Applications International Corporation (SAIC) use neutron detectors based upon 3He-filled gas proportional counters, which are the most common large neutron detector. There is a declining supply of 3He in the world, and thus, methods to reduce the use of this gas in RPMs with minimal changes to the current system designs and sensitivity to cargo-borne neutrons are being investigated. Four technologies have been identified as being currently commercially available, potential alternative neutron detectors to replace the use of 3He in RPMs. Reported here are the results of tests of a newly designed boron-lined proportional counter option. This testing measured the neutron detection efficiency and gamma ray rejection capabilities of two successive prototypes of a system manufactured by GE Reuter Stokes.

  14. Boron-Lined Neutron Detector Measurements

    SciTech Connect (OSTI)

    Lintereur, Azaree T.; Kouzes, Richard T.; Ely, James H.; Erikson, Luke E.; Siciliano, Edward R.

    2009-11-02

    Radiation portal monitors used for interdiction of illicit materials at borders include highly sensitive neutron detection systems. The main reason for having neutron detection capability is to detect fission neutrons from plutonium. The currently deployed radiation portal monitors (RPMs) from Ludlum and Science Applications International Corporation (SAIC) use neutron detectors based upon 3He-filled gas proportional counters, which are the most common large neutron detector. There is a declining supply of 3He in the world, and thus, methods to reduce the use of this gas in RPMs with minimal changes to the current system designs and sensitivity to cargo-borne neutrons are being investigated. Four technologies have been identified as being currently commercially available, potential alternative neutron detectors to replace the use of 3He in RPMs. Reported here are the results of tests of a newly designed boron-lined proportional counter option. This testing measured the neutron detection efficiency and gamma ray rejection capabilities of a system manufactured by Reuter Stokes.

  15. The transcriptional diversity of 25 Drosophila cell lines

    SciTech Connect (OSTI)

    Cherbas, Lucy; Willingham, Aarron; Zhang, Dayu; Yang, Li; Zou, Yi; Eads, Brian D.; Carlson, Joseph W.; Landolin, Jane M.; Kapranov, Philipp; Dumais, Jacqueline; Samsonova, Anastasia; Choi, Jeong-Hyeon; Roberts, Johnny; Davis, Carrie A.; Tang, Haixu; van Baren, Marijke J.; Ghosh, Srinka; Dobin, Alexander; Bell, Kim; Lin, Wei; Langton, Laura; Duff, Michael O.; Tenney, Aaron E.; Zaleski, Chris; Brent, Michael R.; Hoskins, Roger A.; Kaufman, Thomas C.; Andrews, Justen; Graveley, Brenton R.; Perrimon, Norbert; Celniker, Susan E.; Gingeras, Thomas R.; Cherbas, Peter

    2010-11-15

    Drosophila melanogaster cell lines are important resources for cell biologists. Here, we catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines. Unannotated transcription is substantial (typically 19% of euchromatic signal). Conservatively, we identify 1405 novel transcribed regions; 684 of these appear to be new exons of neighboring, often distant, genes. Sixty-four percent of genes are expressed detectably in at least one line, but only 21% are detected in all lines. Each cell line expresses, on average, 5885 genes, including a common set of 3109. Expression levels vary over several orders of magnitude. Major signaling pathways are well represented: most differentiation pathways are off and survival/growth pathways on. Roughly 50% of the genes expressed by each line are not part of the common set, and these show considerable individuality. Thirty-one percent are expressed at a higher level in at least one cell line than in any single developmental stage, suggesting that each line is enriched for genes characteristic of small sets of cells. Most remarkable is that imaginal discderived lines can generally be assigned, on the basis of expression, to small territories within developing discs. These mappings reveal unexpected stability of even fine-grained spatial determination. No two cell lines show identical transcription factor expression. We conclude that each line has retained features of an individual founder cell superimposed on a common cell line gene expression pattern. Wereport the transcriptional profiles of 25 Drosophila melanogaster cell lines, principally by whole-genome tiling microarray analysis of total RNA, carried out as part of the modENCODE project. The data produced in this study add to our knowledge of the cell lines and of the Drosophila transcriptome in several ways. We summarize the expression of previously annotated genes in each of the 25 lines with emphasis on what those patterns reveal

  16. Radio frequency communication system utilizing radiating transmission lines

    DOE Patents [OSTI]

    Struven, Warren C.

    1984-01-01

    A radio communication system for use in tunnels, mines, buildings or other shielded locations in which a pair of radiating transmission lines (30), (31) extend through such location in spaced coextensive relation to each other. Each transmission line (30), (31) has at least one unidirectional amplifier (32), (33) interposed therein with the sense of the unidirectional amplifier (32) of one transmission line (30) being opposite to the sense of the unidirectional amplifier (33) of the other transmission line (31). Each of the amplifiers (32), (33) has a gain which is less than the coupling loss between the transmission lines (30), (31). Two or more mobile transceivers (35) in the location served by the system are coupled to the transmission lines (30), (31) by electromagnetic wave propagation in space in order to communicate directly with each other at a given radio frequency within the frequency range of the system.

  17. Living and Working Safely Around High-Voltage Power Lines.

    SciTech Connect (OSTI)

    United States. Bonneville Power Administration.

    2001-06-01

    High-voltage transmission lines can be just as safe as the electrical wiring in the homes--or just as dangerous. The crucial factor is ourselves: they must learn to behave safely around them. This booklet is a basic safety guide for those who live and work around power lines. It deals primarily with nuisance shocks due to induced voltages, and with potential electric shock hazards from contact with high-voltage lines. References on possible long-term biological effects of transmission lines are shown. In preparing this booklet, the Bonneville Power Administration has drawn on more than 50 years of experience with high-voltage transmission. BPA operates one of the world`s largest networks of long-distance, high-voltage lines. This system has more than 400 substations and about 15,000 miles of transmission lines, almost 4,400 miles of which are operated at 500,000 volts.

  18. Sensor, method and system of monitoring transmission lines

    DOE Patents [OSTI]

    Syracuse, Steven J.; Clark, Roy; Halverson, Peter G.; Tesche, Frederick M.; Barlow, Charles V.

    2012-10-02

    An apparatus, method, and system for measuring the magnetic field produced by phase conductors in multi-phase power lines. The magnetic field measurements are used to determine the current load on the conductors. The magnetic fields are sensed by coils placed sufficiently proximate the lines to measure the voltage induced in the coils by the field without touching the lines. The x and y components of the magnetic fields are used to calculate the conductor sag, and then the sag data, along with the field strength data, can be used to calculate the current load on the line and the phase of the current. The sag calculations of this invention are independent of line voltage and line current measurements. The system applies a computerized fitter routine to measured and sampled voltages on the coils to accurately determine the values of parameters associated with the overhead phase conductors.

  19. Analytical models of calcium binding in a calcium channel

    SciTech Connect (OSTI)

    Liu, Jinn-Liang; Eisenberg, Bob

    2014-08-21

    The anomalous mole fraction effect of L-type calcium channels is analyzed using a Fermi like distribution with the experimental data of Almers and McCleskey [J. Physiol. 353, 585 (1984)] and the atomic resolution model of Lipkind and Fozzard [Biochemistry 40, 6786 (2001)] of the selectivity filter of the channel. Much of the analysis is algebraic, independent of differential equations. The Fermi distribution is derived from the configuration entropy of ions and water molecules with different sizes, different valences, and interstitial voids between particles. It allows us to calculate potentials and distances (between the binding ion and the oxygen ions of the glutamate side chains) directly from the experimental data using algebraic formulas. The spatial resolution of these results is comparable with those of molecular models, but of course the accuracy is no better than that implied by the experimental data. The glutamate side chains in our model are flexible enough to accommodate different types of binding ions in different bath conditions. The binding curves of Na{sup +} and Ca{sup 2+} for [CaCl{sub 2}] ranging from 10{sup −8} to 10{sup −2} M with a fixed 32 mM background [NaCl] are shown to agree with published Monte Carlo simulations. The Poisson-Fermi differential equation—that includes both steric and correlation effects—is then used to obtain the spatial profiles of energy, concentration, and dielectric coefficient from the solvent region to the filter. The energy profiles of ions are shown to depend sensitively on the steric energy that is not taken into account in the classical rate theory. We improve the rate theory by introducing a steric energy that lumps the effects of excluded volumes of all ions and water molecules and empty spaces between particles created by Lennard-Jones type and electrostatic forces. We show that the energy landscape varies significantly with bath concentrations. The energy landscape is not constant.

  20. Hydroxyapatite-binding peptides for bone growth and inhibition

    DOE Patents [OSTI]

    Bertozzi, Carolyn R.; Song, Jie; Lee, Seung-Wuk

    2011-09-20

    Hydroxyapatite (HA)-binding peptides are selected using combinatorial phage library display. Pseudo-repetitive consensus amino acid sequences possessing periodic hydroxyl side chains in every two or three amino acid sequences are obtained. These sequences resemble the (Gly-Pro-Hyp).sub.x repeat of human type I collagen, a major component of extracellular matrices of natural bone. A consistent presence of basic amino acid residues is also observed. The peptides are synthesized by the solid-phase synthetic method and then used for template-driven HA-mineralization. Microscopy reveal that the peptides template the growth of polycrystalline HA crystals .about.40 nm in size.

  1. Functionalized polymers for binding to solutes in aqueous solutions

    DOE Patents [OSTI]

    Smith, Barbara F.; Robison, Thomas W.

    2006-11-21

    A functionalized polymer for binding a dissolved molecule in an aqueous solution is presented. The polymer has a backbone polymer to which one or more functional groups are covalently linked. The backbone polymer can be such polymers as polyethylenimine, polyvinylamine, polyallylamine, and polypropylamine. These polymers are generally water-soluble, but can be insoluble when cross-linked. The functional group can be for example diol derivatives, polyol derivatives, thiol and dithiol derivatives, guest-host groups, affinity groups, beta-diphosphonic acids, and beta-diamides

  2. DOE-EPRI On-Line Monitoring Implementation Guidelines

    SciTech Connect (OSTI)

    E. Davis, R. Bickford

    2003-01-02

    Industry and EPRI experience at several plants has shown on-line monitoring to be very effective in identifying out-of-calibration instrument channels or indications of equipment-degradation problems. The EPRI implementation project for on-line monitoring has demonstrated the feasability of on-line monitoring at several participating nuclear plants. The results have been very enouraging, and substantial progress is anticipated in the coming years.

  3. Inertial confinement fusion method producing line source radiation fluence

    DOE Patents [OSTI]

    Rose, Ronald P.

    1984-01-01

    An inertial confinement fusion method in which target pellets are imploded in sequence by laser light beams or other energy beams at an implosion site which is variable between pellet implosions along a line. The effect of the variability in position of the implosion site along a line is to distribute the radiation fluence in surrounding reactor components as a line source of radiation would do, thereby permitting the utilization of cylindrical geometry in the design of the reactor and internal components.

  4. Strengthening the Front Lines: Sales Training and Continuing Education for

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Contractors | Department of Energy the Front Lines: Sales Training and Continuing Education for Contractors Strengthening the Front Lines: Sales Training and Continuing Education for Contractors Better Buildings Residential Network Peer Exchange Call Series: Strengthening the Front Lines: Sales Training and Continuing Education for Contractors, call slides and discussion summary. Call Slides and Discussion Summary (2.11 MB) More Documents & Publications Staged Upgrades -

  5. EM Recovery Act Top Line Messages | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Top Line Messages EM Recovery Act Top Line Messages The latest Recovery Act performance related information and metrics. EM Recovery Act Top Line Messages - April, 2013 (1.96 MB) More Documents & Publications Workers at Hanford Site Achieve Recovery Act Legacy Cleanup Goals Ahead of Schedule Audit Report: IG-0426 Testimony of Mark Whitney Principal Deputy Assistant Secretary for Environmental Management Before the Subcommittee on Environment and the Economy House Energy and Commerce

  6. TRANSPORT OF WASTE SIMULANTS IN PJM VENT LINES

    SciTech Connect (OSTI)

    Qureshi, Z

    2007-02-21

    The experimental work was conducted to determine whether there is a potential for waste simulant to transport or 'creep' up the air link line and contaminate the pulse jet vent system, and possibly cause long term restriction of the air link line. Additionally, if simulant creep occurred, establish operating parameters for washing down the line. The amount of the addition of flush fluids and mixer downtime must be quantified.

  7. DOE Seeking Information on Transmission Line Permitting | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Seeking Information on Transmission Line Permitting DOE Seeking Information on Transmission Line Permitting February 27, 2012 - 3:25pm Addthis The Department of Energy's Office of Electricity Delivery and Energy Reliability is seeking information on the questions related to permitting of transmission lines. Infrastructure projects - such as high voltage, long distance, electric transmission facilities - often involve multiple Federal, State, local, and Tribal authorizations and are

  8. Monolithic torpedo bottle lining at Weirton Steel Corporation

    SciTech Connect (OSTI)

    Baker, R.; Griffith, E.

    1996-12-31

    In late 1992 and early 1993 Weirton Steel burned through three torpedo bottles in a three-month period. To determine the cause of the burn throughs, a thorough review of bottle maintenance practices was initiated. Upon identification of contributing factors, changes in operating practices were made. In an effort to increase bottle reliability, lining trials were initiated. Among the trials, a monolithic lining was installed and this paper will discuss results of the lining to date.

  9. Clean Line Plains and Eastern Section 1222 Decision Documents | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Clean Line Plains and Eastern Section 1222 Decision Documents Clean Line Plains and Eastern Section 1222 Decision Documents On March 25, 2016, U.S. Secretary of Energy Dr. Ernest Moniz announced that the Department of Energy (DOE) will participate in the development of the Plains & Eastern Clean Line project (Project), a major clean energy infrastructure project. Through section 1222 of the Energy Policy Act of 2005, Congress authorized DOE to promote electric transmission

  10. In-line phase shift tomosynthesis

    SciTech Connect (OSTI)

    Hammonds, Jeffrey C.; Price, Ronald R.; Pickens, David R.; Donnelly, Edwin F.

    2013-08-15

    Purpose: The purpose of this work is to (1) demonstrate laboratory measurements of phase shift images derived from in-line phase-contrast radiographs using the attenuation-partition based algorithm (APBA) of Yan et al.[Opt. Express 18(15), 1607416089 (2010)], (2) verify that the APBA reconstructed images obey the linearity principle, and (3) reconstruct tomosynthesis phase shift images from a collection of angularly sampled planar phase shift images.Methods: An unmodified, commercially available cabinet x-ray system (Faxitron LX-60) was used in this experiment. This system contains a tungsten anode x-ray tube with a nominal focal spot size of 10 ?m. The digital detector uses CsI/CMOS with a pixel size of 50 50 ?m. The phantoms used consisted of one acrylic plate, two polystyrene plates, and a habanero pepper. Tomosynthesis images were reconstructed from 51 images acquired over a 25 arc. All phase shift images were reconstructed using the APBA.Results: Image contrast derived from the planar phase shift image of an acrylic plate of uniform thickness exceeded the contrast of the traditional attenuation image by an approximate factor of two. Comparison of the planar phase shift images from a single, uniform thickness polystyrene plate with two polystyrene plates demonstrated an approximate linearity of the estimated phase shift with plate thickness (?1600 rad vs ?2970 rad). Tomographic phase shift images of the habanero pepper exhibited acceptable spatial resolution and contrast comparable to the corresponding attenuation image.Conclusions: This work demonstrated the feasibility of laboratory-based phase shift tomosynthesis and suggests that phase shift imaging could potentially provide a new imaging biomarker. Further investigation will be needed to determine if phase shift contrast will be able to provide new tissue contrast information or improved clinical performance.

  11. A simple line wave generator using commercial explosives

    SciTech Connect (OSTI)

    Morris, John S; Jackson, Scott I; Hill, Larry G

    2009-01-01

    We present a simple and inexpensive explosive line wave generator has been designed using commercial sheet explosive and plane wave lens concepts. The line wave generator is constructed using PETN and RDX based sheet explosive for the slow and fast components respectively. The design permits the creation of any desired line width. A series of experiments were performed on a 100 mm design, measuring the detonation arrival time at the output of the generator using a streak camera. An iterative technique was used to adjust the line wave generator's slow and fast components, so as to minimize the arrival time deviation. Designs, test results, and concepts for improvements will be discussed.

  12. Historical Time Line and Information About the Hanford Site

    SciTech Connect (OSTI)

    Briggs, James D.

    2001-03-07

    Historical time line of the Hanford Site spanning from 1940 through 1997, including photographs and other information regarding the town sites and living conditions.

  13. Hawaii Clean Energy Initiative - Transmission Line Approval Permit...

    Open Energy Info (EERE)

    Reference LibraryAdd to library PermittingRegulatory Guidance - Instructions: Hawaii Clean Energy Initiative - Transmission Line Approval Permit PacketPermittingRegulatory...

  14. Secretary Bodman Praises Western States' "Frontier Line" | Department...

    Office of Environmental Management (EM)

    Secretary Bodman Praises Western States' "Frontier Line" April 5, 2005 - 11:30am Addthis WASHINGTON, DC - Secretary of Energy Samuel W. Bodman today released the following ...

  15. Line VISAR and post-shot metallography comparisons for spall...

    Office of Scientific and Technical Information (OSTI)

    Title: Line VISAR and post-shot metallography comparisons for spall analysis. No abstract prepared. Authors: Furnish, Michael David ; Bingert, John F. 1 ; Gray, George T., Jr. ...

  16. EIS-0499: Great Northern Transmission Line Project, Minnesota...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EIS-0499: Great Northern Transmission Line Project, Minnesota Summary This EIS will evaluate the potential environmental impacts of a DOE proposal to grant a Presidential permit to ...

  17. Section 1222 Program - Proposed Plains & Eastern Clean Line Project...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Section 1222 Program - Proposed Plains & Eastern Clean Line ... through the Southwestern Power Administration ... NEPA Website, and through other channels of communication. ...

  18. Wireless Sensor Network for Electric Transmission Line Monitoring...

    Office of Scientific and Technical Information (OSTI)

    Technical Report: Wireless Sensor Network for Electric Transmission Line Monitoring Citation Details In-Document Search Title: Wireless Sensor Network for Electric Transmission ...

  19. EIS-0325: Schultz-Hanford Area Transmission Line Project, WA

    Broader source: Energy.gov [DOE]

    BPA proposes to construct a new 500-kilovolt (kV) transmission line in central Washington. This project would increase transmission system capacity north of Hanford.

  20. EIS-0317: Kangley-Echo Lake Transmission Line Project

    Broader source: Energy.gov [DOE]

    This EIS analyzes BPA's proposal to build a new transmission line to accommodate increasing demand for electricity and ensure reliability in the Puget Sound area.

  1. EIS-0474: Southline Transmission Line Project; Arizona and New...

    Broader source: Energy.gov (indexed) [DOE]

    consist of a new 225-mile transmission line between existing substations at Afton, New Mexico, and Apache, Arizona, and improvements to approximately 130 miles of existing...

  2. Proposed Southline Transmission Line Project - Volume 4 of 4...

    Office of Environmental Management (EM)

    2 Appendix J J-1 Southline Transmission Line Project Draft Environmental Impact Statement and Draft Resource Management Plan Amendment BLM LAND USE AUTHORIZATIONS 1...

  3. Development of aerogel-lined targets for inertial confinement...

    Office of Scientific and Technical Information (OSTI)

    aerogel-lined targets for inertial confinement fusion experiments Braun, T 36 MATERIALS SCIENCE Abstract not provided Lawrence Livermore National Laboratory (LLNL), Livermore, CA...

  4. Guide to Permitting Electric Transmission Lines in Wyoming |...

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library PermittingRegulatory Guidance - GuideHandbook: Guide to Permitting Electric Transmission Lines in WyomingPermitting...

  5. EIS-0514: Colusa-Sutter 500-kilovolt Transmission Line Project...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Colusa and Sutter Counties, California EIS-0514: Colusa-Sutter 500-kilovolt Transmission Line Project; Colusa and Sutter Counties, California Summary Western Area Power ...

  6. Magnetic Field Line Tracing Calculations for Conceptual PFC Design...

    Office of Scientific and Technical Information (OSTI)

    enabling the investigation of high beta physics in a compact stellarator geometry. ... In this paper, we report on the magnetic field line tracing calculations used to evaluate ...

  7. Southline Transmission Line Project - Volume 1 Front Matter

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Infrastructure Program TPE total potential effect tpy ton(s) per year UAS FTC Unmanned Aircraft Systems Flight Test Center Southline Transmission Line Project Final ...

  8. Suggested Practices for Avian Protection on Power Lines | Open...

    Open Energy Info (EERE)

    with federal laws protecting and enhancing avian populations, and maintaining the reliability of electric power networds. Author Avian Power Line Interaction Committee...

  9. Line spectrum and ion temperature measurements from tungsten...

    Office of Scientific and Technical Information (OSTI)

    Tungsten ions were distributed in the LHD plasma by injecting a pellet consisting of a small piece of tungsten metal and polyethylene tube. Many lines having different wavelengths ...

  10. Salt Waste Processing Facility, Line Management Review Board Charter

    Broader source: Energy.gov [DOE]

    The Line Management Review Board (LMRB) serves an important oversight function to monitor the readiness processes and associated deliverables for the Salt Waste Processing Facility (SWPF). The...

  11. Secretary Chu Visits Russian Seaport, Checks Out Second Line...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Part of our effort to secure vulnerable nuclear material around the world, the Second Line of Defense program works to crack down on nuclear smuggling by installing radiation ...

  12. Sandia Energy - Digital In-Line Holography Helps Researchers...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    droplets of fuel are generated and behave in such cases. Sandia researchers developed 3-D measurement techniques based on digital in-line holography (DIH). Sandia advanced DIH...

  13. second line of defense | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    second line of defense Proliferation Detection The Office of Proliferation Detection (PD) develops capabilities to detect special nuclear materials and weapons production and ...

  14. Request for Information on Permitting of Transmission Lines:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Volume 77, No. 38 - Feb. 27, 2012 Request for Information on Permitting of Transmission Lines: Federal Register Notice Volume 77, No. 38 - Feb. 27, 2012 The Department of ...

  15. EIS-0499: Great Northern Transmission Line Project, Minnesota...

    Broader source: Energy.gov (indexed) [DOE]

    and connect a new 883-megawatt electric transmission system across the U.S.-Canada border. The proposed 220 mile transmission line would cross the border near Roseau,...

  16. Energy Department Announces Participation in Clean Line's Large...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    transmission infrastructure was beginning to show its age and needed modernization. ... This means Clean Line will need to execute significant firm transmission service ...

  17. EIS-0463: Northern Pass Transmission Line Project, New Hampshire...

    Broader source: Energy.gov (indexed) [DOE]

    permit to Northern Pass Transmission, LLC, to construct, operate, maintain, and connect a new electric transmission line across the U.S.-Canada border in northern New Hampshire. ...

  18. Electrical and Biological Effects of Transmission Lines: A Review.

    SciTech Connect (OSTI)

    Lee, Jack M.

    1989-06-01

    This review describes the electrical properties of a-c and d-c transmission lines and the resulting effects on plants, animals, and people. Methods used by BPA to mitigate undesirable effects are also discussed. Although much of the information in this review pertains to high-voltage transmission lines, information on distribution lines and electrical appliances is included. The electrical properties discussed are electric and magnetic fields and corona: first for alternating-current (a-c) lines, then for direct current (d-c).

  19. EIS-0483: Estes to Flatiron Substation Transmission Lines Rebuild...

    Energy Savers [EERE]

    Colorado. EIS-0483: Estes to Flatiron Substation Transmission Lines Rebuild Project Public Comment Opportunities No public comment opportunities available at this time....

  20. Appendix S-51 - Transmission Line Approval - Public Utilities...

    Open Energy Info (EERE)

    from "http:en.openei.orgwindex.php?titleAppendixS-51-TransmissionLineApproval-PublicUtilitiesCommission&oldid800735" Feedback Contact needs updating Image needs...

  1. EIS-0502: Hot Springs to Anaconda Transmission Line Rebuild Project...

    Energy Savers [EERE]

    Springs to Anaconda Transmission Line Rebuild Project, Montana SUMMARY DOE's Bonneville Power Administration (BPA) is preparing an EIS that will analyze the potential environmental...

  2. Office of Enterprise Assessments Review of Field Element Line...

    Office of Environmental Management (EM)

    SNL Sandia National Laboratories ii Office of Enterprise Assessments Review of Field Element Line Management Oversight at Sandia National Laboratories EXECUTIVE SUMMARY The...

  3. Pathogenicity of the BRCA1 Missense Variant M1775K is Determined by the Disruption of the BRCT Phosphopeptide-Binding Pocket: a Multi-Modal Approach

    SciTech Connect (OSTI)

    Tischkowitz,M.; Hamel, N.; Carvalho, M.; Birrane, G.; Soni, A.; van Beers, E.; Joosse, S.; Wong, N.; Novak, D.; et al

    2008-01-01

    A number of germ-line mutations in the BRCA1 gene confer susceptibility to breast and ovarian cancer. However, it remains difficult to determine whether many single amino-acid (missense) changes in the BRCA1 protein that are frequently detected in the clinical setting are pathologic or not. Here, we used a combination of functional, crystallographic, biophysical, molecular and evolutionary techniques, and classical genetic segregation analysis to demonstrate that the BRCA1 missense variant M1775K is pathogenic. Functional assays in yeast and mammalian cells showed that the BRCA1 BRCT domains carrying the amino-acid change M1775K displayed markedly reduced transcriptional activity, indicating that this variant represents a deleterious mutation. Importantly, the M1775K mutation disrupted the phosphopeptide-binding pocket of the BRCA1 BRCT domains, thereby inhibiting the BRCA1 interaction with the proteins BRIP1 and CtIP, which are involved in DNA damage-induced checkpoint control. These results indicate that the integrity of the BRCT phosphopeptide-binding pocket is critical for the tumor suppression function of BRCA1. Moreover, this study demonstrates that multiple lines of evidence obtained from a combination of functional, structural, molecular and evolutionary techniques, and classical genetic segregation analysis are required to confirm the pathogenicity of rare variants of disease-susceptibility genes and obtain important insights into the underlying pathogenetic mechanisms.

  4. Situ soil sampling probe system with heated transfer line

    DOE Patents [OSTI]

    Robbat, Jr., Albert

    2002-01-01

    The present invention is directed both to an improved in situ penetrometer probe and to a heated, flexible transfer line. The line and probe may be implemented together in a penetrometer system in which the transfer line is used to connect the probe to a collector/analyzer at the surface. The probe comprises a heater that controls a temperature of a geologic medium surrounding the probe. At least one carrier gas port and vapor collection port are located on an external side wall of the probe. The carrier gas port provides a carrier gas into the geologic medium, and the collection port captures vapors from the geologic medium for analysis. In the transfer line, a flexible collection line that conveys a collected fluid, i.e., vapor, sample to a collector/analyzer. A flexible carrier gas line conveys a carrier gas to facilitate the collection of the sample. A system heating the collection line is also provided. Preferably the collection line is electrically conductive so that an electrical power source can generate a current through it so that the internal resistance generates heat.

  5. Quasimolecules and spectral line broadening in dense plasmas

    SciTech Connect (OSTI)

    Arranz, J. P.; Butaux, J.; Nguyen, H.; Reggadi, A.

    1997-01-05

    The energy levels and transition probabilities for transient diatomic molecules have been obtained by means of a self-consistent field method and used to compute the static and dynamical NeX Lyman {alpha} and Lyman {beta} line profiles emitted from dense plasmas. The typical excitation of molecular satellite lines is pointed out.

  6. Great Northern Transmission Line Floodplain and Wetland Assessment

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Floodplain and Wetland Assessment Prepared for U.S. Department of Energy Office of Electricity Delivery and Energy Reliability January 2016 Great Northern Transmission Line Floodplain and Wetland Assessment Prepared for U.S. Department of Energy Office of Electricity Delivery and Energy Reliability January 2016 i Great Northern Transmission Line Floodplain and Wetland Assessment January 2016 Contents 1.0 Introduction

  7. Trichloroethylene toxicity in a human hepatoma cell line

    SciTech Connect (OSTI)

    Thevenin, E.; McMillian, J.

    1994-12-31

    The experiments conducted in this study were designed to determine the usefullness of hepatocyte cultures and a human hepatoma cell line as model systems for assessing human susceptibility to hepatocellular carcinoma due to exposure to trichloroethylene. The results from these studies will then be analyzed to determine if human cell lines can be used to conduct future experiments of this nature.

  8. Lane-Wendson No. 1 Transmission Line Rebuild Project

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lane-Wendson No. 1 Transmission Line Rebuild Project Finding of No Significant Impact and Floodplain and Wetland Statement of Findings 1 In cooperation with the Bureau of Land Management Lane-Wendson No. 1 Transmission Line Rebuild Project Finding of No Significant Impact and Floodplain and Wetland Statement of Findings DEPARTMENT OF ENERGY Bonneville Power Administration DOE/EA-1952 April 2016 _____________________________________________________________________________________________________

  9. Initial analyses of surface spectral radiance between observations and Line-By-Line calculations

    SciTech Connect (OSTI)

    Brown, P.D.; Clough, S.A.; Miller, N.E.; Shippert, T.R.; Turner, D.D.

    1996-04-01

    The evaluation an improvement of radiative transfer calculations are essential to attain improved performance of general circulation models (GCMs) for climate change applications. A Quality Measurement Experiment (QME) is being conducted to analyze the spectral residuals between the downwelling longwave radiance measured by the University of Wisconsin Atmospheric Emitted Radiance Interferometer (AERI) and spectral radiance calculated by the Line-By-Line Radiative Transfer Model (LBLRTM). The three critical components of this study are (1) the assessment of the quality of the high resolution AERI measurements, (2) the assessment of the ability to define the atmospheric state in the radiating column, and (3) the evaluation of the capability of LBLRTM. Validations have been performed on spectral radiance data, obtained from April 1994 through July 1994, through the analysis of the spectral interval and physical process. The results are archived as a function of time, enabling the retrieval of specific data and facilitating investigations and diurnal effects, seasonal effects, and longer-term trends. While the initial focus is restricted to clear-sky analyses, efforts are under way to include the effects of clouds and aerosols. Plans are well formulated for the extension of the current approach to the shortwave. An overview of the concept of the QME is described by Miller et al. (1994), and a detailed description of this study is provided by Clough et al. (1994).

  10. Yield Line Evaluation Methodology for Reinforced Concrete Structures

    Energy Science and Technology Software Center (OSTI)

    1998-12-30

    Yield line theory is an analytical technique that can be used to determine the ultimate bending capacity of flat reinforced concrete plates subject to distributed and concentrated loadings. Alternately, yield line theory, combined with rotation limits can be used to determine the energy absorption capacity of plates subject to impulsive and impact loadings. Typical components analyzed by yield line theory are basemats, floor and roof slabs subject to vertical loads along with walls subject tomore » out of plane loadings. One limitation of yield line theory is that it is computationally difficult to evaluate some mechanisms. This problem is aggravated by the complex geometry and reinforcing layouts commonly found in practice. The program has the capability to either evaluate a single user defined mechanism or to iterate over a range of mechanisms to determine the minimum ultimate capacity. The program is verified by comparison to a series of yield line mechanisms with known solutions.« less

  11. Continuous human cell lines and method of making same

    DOE Patents [OSTI]

    Stampfer, Martha R.

    1989-01-01

    Substantially genetically stable continuous human cell lines derived from normal human mammary epithelial cells (HMEC) and processes for making and using the same. In a preferred embodiment, the cell lines are derived by treating normal human mammary epithelial tissue with a chemical carcinogen such as benzo[a]pyrene. The novel cell lines serve as useful substrates for elucidating the potential effects of a number of toxins, carcinogens and mutagens as well as of the addition of exogenous genetic material. The autogenic parent cells from which the cell lines are derived serve as convenient control samples for testing. The cell lines are not neoplastically transformed, although they have acquired several properties which distinguish them from their normal progenitors.

  12. Continuous human cell lines and method of making same

    DOE Patents [OSTI]

    Stampfer, M.R.

    1985-07-01

    Substantially genetically stable continuous human cell lines derived from normal human mammary epithelial cells (HMEC) and processes for making and using the same. In a preferred embodiment, the cell lines are derived by treating normal human mammary epithelial tissue with a chemical carcinogen such as benzo(a)pyrene. The novel cell lines serve as useful substrates for elucidating the potential effects of a number of toxins, carcinogens and mutagens as well as of the addition of exogenous genetic material. The autogenic parent cells from which the cell lines are derived serve as convenient control samples for testing. The cell lines are not neoplastically transformed, although they have acquired several properties which distinguish them from their normal progenitors. 2 tabs.

  13. Non-coherent continuum scattering as a line polarization mechanism

    SciTech Connect (OSTI)

    Del Pino Alemán, T.; Manso Sainz, R.; Trujillo Bueno, J. E-mail: rsainz@iac.es

    2014-03-20

    Line scattering polarization can be strongly affected by Rayleigh scattering at neutral hydrogen and Thomson scattering at free electrons. Often a depolarization of the continuum results, but the Doppler redistribution produced by the continuum scatterers, which are light (hence, fast), induces more complex interactions between the polarization in spectral lines and in the continuum. Here we formulate and solve the radiative transfer problem of scattering line polarization with non-coherent continuum scattering consistently. The problem is formulated within the spherical tensor representation of atomic and light polarization. The numerical method of solution is a generalization of the Accelerated Lambda Iteration that is applied to both the atomic system and the radiation field. We show that the redistribution of the spectral line radiation due to the non-coherence of the continuum scattering may modify the shape of the emergent fractional linear polarization patterns significantly, even yielding polarization signals above the continuum level in intrinsically unpolarizable lines.

  14. Profiled spectral lines generated in the field of Kerr superspinars

    SciTech Connect (OSTI)

    Schee, Jan; Stuchlk, Zdenek E-mail: zdenek.stuchlik@fpf.slu.cz

    2013-04-01

    String Theory suggests existence of primordial Kerr superspinars, extremely compact objects with external spacetime described by the Kerr naked singularity geometry. The primordial Kerr superspinars have to be converted to a near-extreme black hole due to accretion, but they could survive to the era of highly redshifted quasars. We study the shape of the profiled spectral lines generated by radiating rings or the innermost parts of Keplerian discs orbiting the Kerr superspinars. Influence of the superspinar surface location on the profiled lines is also considered. We demonstrate strong difference of the character of the profiled lines generated by radiating rings for all values of the superspinar spin and all values of the inclination angles of the observer when compared to those generated in the field of Kerr black holes. For small and mediate inclination angles there are large quantitative differences in the extension and position of the lines. For large inclination angles even strong qualitative difference appears as the profiled lines have a clear doubled character. The smaller, redshifted region of the profiled line is related to the photons reaching the regions near the superspinar surface. Strong differences are obtained also for profiled lines generated by the innermost parts of Keplerian discs especially in the shape of the line. The influence of the superspinar surface location is reflected in the intermediate parts of the the profiled lines. The line profiles can give a clear signature of the presence of a Kerr superspinar and in principle enable estimates of its surface location since the signatures of the superspinar surface location are of different character as those corresponding to the presence of the black hole horizon.

  15. Thermal Properties of Starch From New Corn Lines as Impacted by Environment and During Line Development

    SciTech Connect (OSTI)

    Elizabeth M. Lenihan

    2003-12-12

    The objectives of this research were to further characterize exotic by adapted corn inbreds by studying the impact of environment on their starch thermal properties, and investigating the development of starch thermal properties during kernel maturation by using differential scanning calorimetry (DSC). A method to expedite identification of unusual starch thermal traits was investigated by examining five corn kernels at a time, instead of one kernel, which the previous screening methods used. Corn lines with known thermal functions were blended with background starch (control) in ratios of unique starch to control starch, and analyzed by using DSC. Control starch was representative of typical corn starch. The values for each ratio within a mutant type were unique ({alpha} < 0.01) for most DSC measurements. These results supported the five-kernel method for rapidly screening large amounts of corn germplasm to identify unusual starch traits. The effects of 5 growing locations on starch thermal properties from exotic by adapted corn and Corn Belt lines were studied using DSC. The warmest location, Missouri, generally produced starch with greater gelatinization onset temperature (T{sub oG}), narrower range of gelatinization (R{sub G}), and greater enthalpy of gelatinization ({Delta}H{sub G}). The coolest location, Illinois, generally resulted in starch with lower T{sub oG}, wider R{sub G}, and lower {Delta}H{sub G}. Starch from the Ames 1 farm had thermal properties similar to those of Illinois, whereas starch from the Ames 2 farm had thermal properties similar to those of Missouri. The temperature at Ames 2 may have been warmer since it was located near a river; however, soil type and quality also were different. Final corn starch structure and function change during development and maturity. Thus, the changes in starch thermal properties during 5 stages of endosperm development from exotic by adapted corn and Corn Belt lines at two locations were studied by using DSC

  16. Development of Gamma-Emitting Receptor Binding Radiopharmace

    SciTech Connect (OSTI)

    Reba, Richard

    2003-02-20

    The long-term objective is to develop blood-brain barrier (BBB) permeable m2-selective (relative to m1, m3, and m4) receptor-binding radiotracers and utilize these radiotracers for quantifying receptor concentrations obtained from PET or SPECT images of human brain. In initial studies, we concluded that the lipophilicity and high affinity prevented (R,S)-I-QNB from reaching a flow-independent and receptor-dependent state in a reasonable time. Thus, it was clear that (R,S)-I-QNB should be modified. Therefore, during the last portion of this funded research, we proposed that more polar heterocycles should help accomplish that. Since reports of others concluded that radiobromination and radiofluorination of the unactivated phenyl ring is not feasible (Newkome et al,,1982), we, therefore, explored during this grant period a series of analogues of (R)-QNB in which one or both of the six-membered phenyl rings is replaced by a five-membered thienyl (Boulay et al., 1995), or furyl ring. The chemistry specific aims were to synthesize novel compounds designed to be m2-selective mAChR ligands capable of penetrating into the CNS, and develop methods for efficient radiolabeling of promising m2-selective muscarinic ligands. The pharmacology specific aims were to determine the affinity and subtype-selectivity of the novel compounds using competition binding studies with membranes from cells that express each of the five muscarinic receptor subtypes, to determine the ability of the promising non-radioactive compounds and radiolabeled novel compounds to cross the BBB, to determine the biodistribution, in-vivo pharmacokinetics, and in-vitm kinetics of promising m2-selective radioligands and to determine the distribution of receptors for the novel m2-selective radioligands using quantitative autoradiography of rat brain, and compare this distribution to the distribution of known m2-selective compounds.

  17. Laboratory measurements of white dwarf photospheric spectral lines: Hβ

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Falcon, Ross Edward; Rochau, Gregory A.; Bailey, James E.; Gomez, Thomas; Montgomery, Michael Houston; Winget, Donald E.; Nagayama, Taisuke

    2015-06-18

    We spectroscopically measure multiple hydrogen Balmer line profiles from laboratory plasmas to investigate the theoretical line profiles used in white dwarf (WD) atmosphere models. X-ray radiation produced at the Z Pulsed Power Facility at Sandia National Laboratories initiates plasma formation in a hydrogen-filled gas cell, replicating WD photospheric conditions. We also present time-resolved measurements of Hβ and fit this line using different theoretical line profiles to diagnose electron density, ne, and n = 2 level population, n2. Aided by synthetic tests, we characterize the validity of our diagnostic method for this experimental platform. During a single experiment, we infer amore » continuous range of electron densities increasing from ne ~ 4 to ~30 × 1016 cm-3 throughout a 120-ns evolution of our plasma. Also, we observe n2 to be initially elevated with respect to local thermodynamic equilibrium (LTE); it then equilibrates within ~55 ns to become consistent with LTE. This also supports our electron-temperature determination of Te ~ 1.3 eV (~15,000 K) after this time. At ne≲ 1017 cm-3, we find that computer-simulation-based line-profile calculations provide better fits (lower reduced χ2) than the line profiles currently used in the WD astronomy community. The inferred conditions, however, are in good quantitative agreement. Lastly, this work establishes an experimental foundation for the future investigation of relative shapes and strengths between different hydrogen Balmer lines.« less

  18. Methods and apparatus for reducing corrosion in refractory linings

    DOE Patents [OSTI]

    Poeppel, Roger B.; Greenberg, Sherman; Diercks, Dwight R.

    1987-01-01

    Methods and apparatus are provided for reducing corrosion in a refractory lining of a liquid-containing vessel used in direct steelmaking processes. The vessel operates at between about 1600.degree. C. and about 1800.degree. C. and an oxygen partial pressure of about 10.sup.-12 atmospheres, creating slag which is rich in FeO. The refractory lining includes a significant level of chromium oxide (Cr.sub.2 O.sub.3), and has small interconnected pores which may be filled with a gas mixture having a higher total pressure and oxygen partial pressure than the total pressure and oxygen partial pressure associted with the liquid against the lining of the vessel. The gas mixture is forced through the pores of the lining so that the pores are continuously filled with the mixture. In this manner, the gas mixture creates a blanket which increases the oxygen partial pressure at the lining enough to maintain the chromium in the lining in a selected valence state in which the chromium has decreased solubility in the FeO slag, thereby reducing corrosion by the FeO and increasing the useful life of the refractory lining.

  19. Applying a Modified Triad Approach to Investigate Wastewater lines

    SciTech Connect (OSTI)

    Pawlowicz, R.; Urizar, L.; Blanchard, S.; Jacobsen, K.; Scholfield, J.

    2006-07-01

    Approximately 20 miles of wastewater lines are below grade at an active military Base. This piping network feeds or fed domestic or industrial wastewater treatment plants on the Base. Past wastewater line investigations indicated potential contaminant releases to soil and groundwater. Further environmental assessment was recommended to characterize the lines because of possible releases. A Remedial Investigation (RI) using random sampling or use of sampling points spaced at predetermined distances along the entire length of the wastewater lines, however, would be inefficient and cost prohibitive. To accomplish RI goals efficiently and within budget, a modified Triad approach was used to design a defensible sampling and analysis plan and perform the investigation. The RI task was successfully executed and resulted in a reduced fieldwork schedule, and sampling and analytical costs. Results indicated that no major releases occurred at the biased sampling points. It was reasonably extrapolated that since releases did not occur at the most likely locations, then the entire length of a particular wastewater line segment was unlikely to have contaminated soil or groundwater and was recommended for no further action. A determination of no further action was recommended for the majority of the waste lines after completing the investigation. The modified Triad approach was successful and a similar approach could be applied to investigate wastewater lines on other United States Department of Defense or Department of Energy facilities. (authors)

  20. Single line reversing system capsular pneumatic freight pipelines

    SciTech Connect (OSTI)

    Weaver, P.B.

    1999-07-01

    In the 1800's the first Pneumatic Tube Systems sent a carrier vertically from one floor to another in a hospital using a foot-powered bellows. The carrier was returned to the starting point down the same tube using gravity. This was the first Single Line Reversing system. As the stations were moved apart horizontally the foot-powered bellows at both ends became ineffective and were replaced with a single blower or exhauster. The blower/exhauster ran continuously therefore a second line for returning carriers to the starting point, had to be installed - hence Twin Line systems. These systems were used for transporting mail, paperwork, medications, steel mill samples, parts, tools, medical lab samples, etc., in hospitals, stores and other businesses. Twin Line systems were very popular until about 1970 at which time installation labor and material costs became expensive and controls were becoming unnecessarily complicated and expensive. These reasons plus new technology forced the return to Single Line Reversing technology. Back in the 1800's three ``people transporting'' subways were built. A fourth system was built under the Pentagon in the 1950's or 1960's. It is difficult to find information on this one. All are Single Line Reversing systems. The difference between a Single Line Reversing and a Twin Line system is exactly as the names imply. The principle of the operation of these systems is covered herein. The physics for these two kinds of systems is the same. The Single Line Reversing system is technically more complex but capital and operating expense is far less costly. These costs are discussed herein.

  1. Identification and characterization of riboflavin-binding proteins in human circulation

    SciTech Connect (OSTI)

    Innis-Whitehouse, W.S.A.

    1988-01-01

    Riboflavin binding by plasma proteins from healthy human subjects was examined by equilibrium dialysis and binding was observed to vary over a greater than 10-fold range. Upon fractionation of plasma by gel filtration, the major riboflavin-binding components eluted with albumin and gamma-globulins. Albumin was purified and found to bind riboflavin only very weakly, although FMN and photo-chemical degradation products were more tightly bound. Most of the binding occurred in the gamma-globulin fraction and was attributed to immunoglobulins because the binding proteins and immunoglobulins copurified using various methods, were removed by treatment of plasma with protein A-agarose, and were coincident upon immuno-electrophoresis followed by autoradiography to detect (2-{sup 14}C)-riboflavin. Binding differences among plasma samples were reflected in the binding recovered with the immunoglobulin fractions; however, there was not a direct relationship between the amount of immunoglobulin and the amount of (2-{sup 14}C)riboflavin bound. Hence, it appeared that the binding was due to a subfraction of immunoglobulins.

  2. Strong and Reversible Binding of Carbon Dioxide in a Green Metal...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Strong and Reversible Binding of Carbon Dioxide in a Green Metal-Organic Framework Previous Next List Jeremiah J. Gassensmith, Hiroyasu Furukawa, Ronald A. Smaldone, Ross S. ...

  3. New perspective on glycoside hydrolase binding to lignin from pretreated corn stover

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Yarbrough, John M.; Mittal, Ashutosh; Mansfield, Elisabeth; Taylor, II, Larry E.; Hobdey, Sarah E.; Sammond, Deanne W.; Bomble, Yannick J.; Crowley, Michael F.; Decker, Stephen R.; Himmel, Michael E.; et al

    2015-12-18

    In this study, non-specific binding of cellulases to lignin has been implicated as a major factor in the loss of cellulase activity during biomass conversion to sugars. It is believed that this binding may strongly impact process economics through loss of enzyme activities during hydrolysis and enzyme recycling scenarios. The current model suggests glycoside hydrolase activities are lost though non-specific/non-productive binding of carbohydrate-binding domains to lignin, limiting catalytic site access to the carbohydrate components of the cell wall.

  4. V-172: ISC BIND RUNTIME_CHECK Error Lets Remote Users Deny Service Against Recursive Resolvers

    Broader source: Energy.gov [DOE]

    A defect exists which allows an attacker to crash a BIND 9 recursive resolver with a RUNTIME_CHECK error in resolver.c

  5. U-227: bind-dyndb-ldap DN Escaping Flaw Lets Remote Users Deny Service

    Broader source: Energy.gov [DOE]

    A vulnerability has been reported in bind-dyndb-ldap, which can be exploited by malicious people to cause a DoS (Denial of Service).

  6. Phone Numbers for Beam Lines and Other Services | Stanford Synchrotron

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Lightsource Phone Numbers for Beam Lines and Other Services The local area code for SSRL is 650. All numbers listed below should be dialed as 650-926-xxxx from other area codes. When calling an onsite location from within SSRL simply dial the 4-digit extension. When calling an offsite number within the 650 area code dial, dial 9 plus the 7-digit number. To call a number in another area code dial 9-1-area code - phone number. Beam Lines Beam Line Extension 1-4 5214 1-5 5215 2-1 5221

  7. Phase II beam lines at the National Synchrotron Light Source

    SciTech Connect (OSTI)

    Thomlinson, W.

    1984-06-01

    The expansion of the National Synchrotron Light Source has been funded by the US Department of Energy. The Phase II program consists of both increased conventional facilities and six new beam lines. In this paper, an overview of the six beam lines which will be constructed during Phase II is presented. For five of the lines special radiation sources are necessary and the designs of four of the devices are complete. The relevant parameters of the insertion devices under construction and development are presented.

  8. Titanium and germanium lined hohlraums and halfraums as multi...

    Office of Scientific and Technical Information (OSTI)

    Titanium and germanium lined hohlraums and halfraums as multi-keV X-ray radiators Citation ... You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This ...

  9. Metal Insertion in a Microporous Metal-Organic Framework Lined...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Metal Insertion in a Microporous Metal-Organic Framework Lined with 2,2 '-Bipyridine Previous Next List E. D. Bloch, D. Britt, C. Lee, C. J. Doonan, F. J. Uribe-Romo, H. Furukawa, ...

  10. Grand Valley Rrl Pwr Line, Inc | Open Energy Information

    Open Energy Info (EERE)

    Valley Rrl Pwr Line, Inc Place: Colorado Website: www.gvp.org Twitter: @GVRuralPower Outage Hotline: 970-242-0040 Outage Map: www.gvp.orgcontentoutage-map References: EIA Form...

  11. Wireless Sensor Network for Electric Transmission Line Monitoring

    SciTech Connect (OSTI)

    Alphenaar, Bruce

    2009-06-30

    Generally, federal agencies tasked to oversee power grid reliability are dependent on data from grid infrastructure owners and operators in order to obtain a basic level of situational awareness. Since there are many owners and operators involved in the day-to-day functioning of the power grid, the task of accessing, aggregating and analyzing grid information from these sources is not a trivial one. Seemingly basic tasks such as synchronizing data timestamps between many different data providers and sources can be difficult as evidenced during the post-event analysis of the August 2003 blackout. In this project we investigate the efficacy and cost effectiveness of deploying a network of wireless power line monitoring devices as a method of independently monitoring key parts of the power grid as a complement to the data which is currently available to federal agencies from grid system operators. Such a network is modeled on proprietary power line monitoring technologies and networks invented, developed and deployed by Genscape, a Louisville, Kentucky based real-time energy information provider. Genscape measures transmission line power flow using measurements of electromagnetic fields under overhead high voltage transmission power lines in the United States and Europe. Opportunities for optimization of the commercial power line monitoring technology were investigated in this project to enable lower power consumption, lower cost and improvements to measurement methodologies. These optimizations were performed in order to better enable the use of wireless transmission line monitors in large network deployments (perhaps covering several thousand power lines) for federal situational awareness needs. Power consumption and cost reduction were addressed by developing a power line monitor using a low power, low cost wireless telemetry platform known as the ''Mote''. Motes were first developed as smart sensor nodes in wireless mesh networking applications. On such a platform

  12. Single transmission line interrogated multiple channel data acquisition system

    DOE Patents [OSTI]

    Fasching, George E.; Keech, Jr., Thomas W.

    1980-01-01

    A single transmission line interrogated multiple channel data acquisition system is provided in which a plurality of remote station/sensor circuits each monitors a specific process variable and each transmits measurement values over a single transmission line to a master interrogating station when addressed by said master interrogating station. Typically, as many as 330 remote stations may be parallel connected to the transmission line which may exceed 7,000 feet. The interrogation rate is typically 330 stations/second. The master interrogating station samples each station according to a shared, charging transmit-receive cycle. All remote station address signals, all data signals from the remote stations/sensors and all power for all of the remote station/sensors are transmitted via a single continuous terminated coaxial cable. A means is provided for periodically and remotely calibrating all remote sensors for zero and span. A provision is available to remotely disconnect any selected sensor station from the main transmission line.

  13. Libby (FEC)-Troy 115kV Line Rebuild

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of McNary Group 2 - Big Eddy to Knight The Big Eddy - Knight 500 kV line and new substation (WOMR Group 2) project is one of five projects recommended out of the 2008 Cluster...

  14. Polymer delineation system. [Patent application: traffic lane lines

    DOE Patents [OSTI]

    Woolman, S.; Steinberg, M.

    1975-06-24

    A delineation system (traffic lane lines) for highways is described in which polymerizable substances are applied to existing or newly prepared highway pavements. The substances would contain a suitable pigment and may incorporate reflective elements.

  15. Guide to good practices for line and training manager activities

    SciTech Connect (OSTI)

    1998-06-01

    The purpose of this guide is to provide direction for line and training managers in carrying out their responsibilities for training and qualifying personnel and to verify that existing training activities are effective.

  16. EA-1891: Alvey-Fairview Transmission Line Rebuild Project, Oregon

    Broader source: Energy.gov [DOE]

    This EA evaluates the environmental impacts of a proposal to rebuild DOE’s Bonneville Power Administration’s Alvey-Fairview No. 1 230-kV transmission line located between Eugene, Oregon, and Coquille, Oregon.

  17. DOE Sustainability Reporting Open Line Help Call | Department...

    Broader source: Energy.gov (indexed) [DOE]

    November 4, 2015 2:00PM to 3:00PM EST The Sustainability Performance Office (SPO) sponsors open line help calls to assist DOE sites and national laboratories with the annual...

  18. Internal-integral sodium return line for sodium heat engine

    DOE Patents [OSTI]

    Hunt, Thomas K.

    1985-01-01

    A thermoelectric generator device which converts heat energy to electrical energy. An alkali metal is used with a solid electrolyte and a portion of the return line for the alkali metal is located within the generator vacuum space.

  19. Soliton communication lines based on spectrally efficient modulation formats

    SciTech Connect (OSTI)

    Yushko, O V; Redyuk, A A

    2014-06-30

    We report the results of mathematical modelling of optical-signal propagation in soliton fibre-optic communication lines (FOCLs) based on spectrally efficient signal modulation formats. We have studied the influence of spontaneous emission noise, nonlinear distortions and FOCL length on the data transmission quality. We have compared the characteristics of a received optical signal for soliton and conventional dispersion compensating FOCLs. It is shown that in the presence of strong nonlinearity long-haul soliton FOCLs provide a higher data transmission performance, as well as allow higher order modulation formats to be used as compared to conventional communication lines. In the context of a coherent data transmission, soliton FOCLs allow the use of phase modulation with many levels, thereby increasing the spectral efficiency of the communication line. (optical communication lines)

  20. Federal Line Management Oversight of Department of Energy Nuclear...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CURRENT DOE G 226.1-2A, Federal Line Management Oversight of Department of Energy Nuclear Facilities by David Weitzman Functional areas: Safety, Oversight The Guide was developed...

  1. Magnetic Field Line Tracing Calculations for Conceptual PFC Design...

    Office of Scientific and Technical Information (OSTI)

    Two methods for tracing the edge field line topology were used in this study. The first ... The details of the magnetic topology differ when computed with VMECMFBE as compared with ...

  2. CRAD, NNSA- Evaluation Site Office Line Oversight Programs

    Broader source: Energy.gov [DOE]

    CRAD for Evaluation Site Office Line Oversight Programs. Criteria Review and Approach Documents (CRADs) that can be used to conduct a well-organized and thorough assessment of elements of safety and health programs.

  3. Federal Line Management Oversight of Department of Energy Nuclear Facilities

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2013-04-04

    The Guide was developed in support of DOE O 226.1B to provide guidance that may be useful to DOE line management organizations in meeting the provisions of that order when applied to nuclear facilities.

  4. EA-1880: Big Bend to Witten Transmission Line Project, South...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to construct, own, and operate an approximately 70-mile long 230-kV single-circuit transmission line that would connect a new switchyard with the existing Witten Substation. ...

  5. Erratum: ''Titanium and germanium lined hohlraums and halfraums...

    Office of Scientific and Technical Information (OSTI)

    Title: Erratum: ''Titanium and germanium lined hohlraums and halfraums as multi-keV x-ray radiators'' Phys. Plasmas 16, 052704 (2009) No abstract prepared. Authors: Girard, F. ; ...

  6. EIS-0106: Great Falls-Conrad Transmission Line Project, Montana

    Broader source: Energy.gov [DOE]

    The Western Area Power Administration prepared this EIS to evaluate the environmental impacts of the construction and operation of a 230-kilovolt transmission line from Great Falls, Montana, to Conrad, Montana.

  7. Microsoft Word - News Release -- Annual Reports now on line 2...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    5 15 BONNEVILLE POWER ADMINISTRATION Friday, Feb. 20, 2015 CONTACT: Mike Hansen, BPA 503-230-4328 or 503-230-5131 All 77 of BPA's annual reports now on line Portland, Ore. - The...

  8. Green Power Transmission Line Given New Life | Department of...

    Office of Environmental Management (EM)

    The transmission line should generate about 150 construction jobs and 50 to 75 green jobs directly related to the wind energy companies, which have secured space for their wind ...

  9. Single-Molecule Dynamics Reveals Cooperative Binding-Folding in Protein Recognition

    SciTech Connect (OSTI)

    Wang, Jin; Lu, Qiang N.; Lu, H PETER.

    2006-07-01

    The study of associations between two biomolecules is the key to understand molecular recognition and function. Molecular function is often thought to be determined by the underlying structures. Here, combining single molecule study of protein binding with an energy landscape inspired microscopic model, we found strong evidences that bio-molecular recognition is determined by flexibilities in addition to structures. Our model is based on coarse grained molecular dynamics performed on the residue level with the energy function biased towards the native binding structure (Go model). With our model, the underlying free energy landscape of the binding can be explored. Two distinct conformational states as free energy minimum, one with partially folding of CBD and significant binding of CBD to CDC42, and another with native folding of CBD and native binding of CBD to CDC42, are clearly seen. This shows the binding process proceeds with significant interface binding of CBD with CDC42 first without complete folding of CBD. Finally binding and folding are coupled with each other cooperatively to reach the native binding state. The single molecule experimental finding of the dynamic fluctuations between the loosely bound and closely bound conformational states can be identified with theoretically calculated free energy minimum and quantitatively explained in our model as a result of binding associated with large conformational changes. Theoretical predictions have identified certain key residues for binding which are consistent with mutational experiments. The combined study provides a test ground for fundamental mechanisms as well as insights into design and further explorations on biomolecular recognition with large conformational changes.

  10. Gas insulated transmission line having tapered particle trapping ring

    DOE Patents [OSTI]

    Cookson, Alan H.

    1982-01-01

    A gas-insulated transmission line includes an outer sheath, an inner conductor, insulating supports and an insulating gas. A particle-trapping ring is secured to each insulating support, and it is comprised of a central portion and two tapered end portions. The ends of the particle trapping ring have a smaller diameter than the central portion of the ring, so as to enable the use of the particle trapping ring in a curved transmission line.

  11. The 2mrad Crossing Angle Interaction Region and Extraction Line

    SciTech Connect (OSTI)

    Appleby, R.; U., Manchester; Angal-Kalinin, D.; Dadoun, O.; Bambade, P.; Parker, B.; Keller, L.; Moffeit, K.; Nosochkov, Y.; Seryi, A.; Spencer, C.; Carter, J.; Royal Holloway, U.of London; Napoly, O.; /DAPNIA, Saclay

    2006-07-12

    A complete optics design for the 2mrad crossing angle interaction region and extraction line was presented at Snowmass 2005. Since this time, the design task force has been working on developing and improving the performance of the extraction line. The work has focused on optimizing the final doublet parameters and on reducing the power losses resulting from the disrupted beam transport. In this paper, the most recent status of the 2mrad layout and the corresponding performance are presented.

  12. Northern Pass Transmission Line Project Environmental Impact Statement:

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Announcement of Change in Public Meeting Location: Federal Register Notice Volume 78, No. 181 - September 18, 2013 | Department of Energy Northern Pass Transmission Line Project Environmental Impact Statement: Announcement of Change in Public Meeting Location: Federal Register Notice Volume 78, No. 181 - September 18, 2013 Northern Pass Transmission Line Project Environmental Impact Statement: Announcement of Change in Public Meeting Location: Federal Register Notice Volume 78, No. 181 -

  13. EIS-0507: Boardman-Hemingway Transmission Line, Oregon and Idaho

    Broader source: Energy.gov [DOE]

    The Bureau of Land Management and the U.S. Forest Service are preparing, with DOE’s Bonneville Power Administration (BPA) as a cooperating agency, an EIS that evaluates the potential environmental impacts of a proposal to construct about 305 miles of 500-kV transmission line from northeast Oregon to southwest Idaho. BPA’s proposed action is to partially fund part the transmission line.

  14. VERNIER CHRONOTRON UTILIZING AT LEAST TWO SHORTED DELAY LINES

    DOE Patents [OSTI]

    Rufer, R.P.

    1964-02-25

    An improved vernier chronotron featuring pulse-forming circuits of a ringing'' or back and forth'' oscillatory type is described. A delay line shorted at both ends together with transistor circuitry to introduce a pulse into that line and also to provide reinforcement of the pulse as it oscillates between the pulse-reflective extremities is provided. A transistorized coincidence circuit is also provided. Enhanced measurement of time intervals in the nanosecond range is afforded. (AEC)

  15. Glosten Associates Tests Innovative High-Strength Mooring Lines for

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Deepwater Offshore Wind Installations | Department of Energy Glosten Associates Tests Innovative High-Strength Mooring Lines for Deepwater Offshore Wind Installations Glosten Associates Tests Innovative High-Strength Mooring Lines for Deepwater Offshore Wind Installations October 1, 2012 - 12:52pm Addthis This is an excerpt from the Third Quarter 2012 edition of the Wind Program R&D Newsletter. Funded by the U.S. Department of Energy's Wind Program, Glosten Associates recently completed

  16. Device For Trapping Laser Pulses In An Optical Delay Line

    DOE Patents [OSTI]

    Yu, David U. L.; Bullock, Donald L.

    1997-12-23

    A device for maintaining a high-energy laser pulse within a recirculating optical delay line for a period time to optimize the interaction of the pulse with an electron beam pulse train comprising closely spaced electron micropulses. The delay line allows a single optical pulse to interact with many of the electron micropulses in a single electron beam macropulse in sequence and for the introduction of additional optical pulses to interact with the micropulses of additional electron beam macropulses. The device comprises a polarization-sensitive beam splitter for admitting an optical pulse to and ejecting it from the delay line according to its polarization state, a Pockels cell to control the polarization of the pulse within the delay line for the purpose of maintaining it within the delay line or ejecting it from the delay line, a pair of focusing mirrors positioned so that a collimated incoming optical pulse is focused by one of them to a focal point where the pulse interacts with the electron beam and then afterwards the pulse is recollimated by the second focusing mirror, and a timing device which synchronizes the introduction of the laser pulse into the optical delay line with the arrival of the electron macropulse at the delay line to ensure the interaction of the laser pulse with a prescribed number of electron micropulses in sequence. In a first embodiment of the invention, the principal optical elements are mounted with their axes collinear. In a second embodiment, all principal optical elements are mounted in the configuration of a ring.

  17. Corrugated outer sheath gas-insulated transmission line

    DOE Patents [OSTI]

    Kemeny, George A.; Cookson, Alan H.

    1981-01-01

    A gas-insulated transmission line includes two transmission line sections each of which are formed of a corrugated outer housing enclosing an inner high-voltage conductor disposed therein, with insulating support means supporting the inner conductor within the outer housing and an insulating gas providing electrical insulation therebetween. The outer housings in each section have smooth end sections at the longitudinal ends thereof which are joined together by joining means which provide for a sealing fixed joint.

  18. Jefferson Lab announces Fall Science Series line up | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fall Science Series line up Jefferson Lab announces Fall Science Series line up September 5, 2003 Jefferson Lab hosts Fall and Spring Science Series to engage the public in a range of current scientific topics. Guest speakers from across the nation are invited to the Lab to present their sometimes entertaining or thought-provoking, but always informative lectures or demonstrations. The Jefferson Lab Fall Science Series kicks off on Tuesday, October 7, with Michael Henchman, a chemistry professor

  19. LLNL line-item construction projects Master Site Plan

    SciTech Connect (OSTI)

    1996-04-15

    This interim submittal is an updated 1996 overview of the Master Plan based on the 1995 LLNL Site Development Plan, illustrating the future land use considerations, and the locations of proposed facilities as documented through the line item development process and keyed to the summary table. The following components in addition to the line-item proposals remain key elements in the implementation strategy of the Master Plan: personnel migration, revitalization, space reduction, classified core contraction, utility systems, and environmental restoration.

  20. Development of aerogel-lined targets for inertial confinement fusion

    Office of Scientific and Technical Information (OSTI)

    experiments (Thesis/Dissertation) | SciTech Connect Thesis/Dissertation: Development of aerogel-lined targets for inertial confinement fusion experiments Citation Details In-Document Search Title: Development of aerogel-lined targets for inertial confinement fusion experiments This thesis explores the formation of ICF compatible foam layers inside of an ablator shell used for inertial confinement fusion experiments at the National Ignition Facility. In particular, the capability of p- DCPD

  1. Reprocessing and Reinterpretation of COCORP Nevada Line 8 Through Nixon

    Office of Scientific and Technical Information (OSTI)

    (Other) | SciTech Connect Reprocessing and Reinterpretation of COCORP Nevada Line 8 Through Nixon Citation Details In-Document Search Title: Reprocessing and Reinterpretation of COCORP Nevada Line 8 Through Nixon Conf Paper Authors: Louie, John [1] + Show Author Affiliations UNR Publication Date: 2013-12-20 OSTI Identifier: 1111655 Report Number(s): DOE-Pyramid-2842-jl11 DOE Contract Number: EE0002842 Resource Type: Other Research Org: Regents of the Nevada System of Higher Education

  2. DOE Sustainability Reporting Open Line Help Call | Department of Energy

    Office of Environmental Management (EM)

    30, 2014 2:00PM to 3:00PM EDT The Sustainability Performance Office (SPO) sponsors open line help calls to assist DOE sites and national laboratories with the annual sustainability reporting process. Representatives from the SPO will be available on the call to answer specific questions with respect to Site Sustainability Plans (SSP), the Consolidated Energy Data Report (CEDR), and the new Sustainability Dashboard. The Open Line call will follow no set format. DOE personnel may call in to ask

  3. Federal Line Management Oversight of Department of Energy Nuclear Facilities

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2011-04-25

    The purpose of this Guide is to provide U.S. Department of Energy (DOE) line management with guidance that may be useful to them in effectively and efficiently implementing the requirements of DOE O 226.1B, Implementation of Department of Energy Oversight Policy, date April 25, 2011, as applied to Federal line management of hazard category 1, 2, and 3 nuclear facilities.

  4. Optical emission line monitor with background observation and cancellation

    DOE Patents [OSTI]

    Goff, D.R.; Notestein, J.E.

    1985-01-04

    A fiber optics based optical emission line monitoring system is provided in which selected spectral emission lines, such as the sodium D-line emission in coal combustion, may be detected in the presence of interferring background or blackbody radiation with emissions much greater in intensity than that of the emission line being detected. A bifurcated fiber optic light guide is adapted at the end of one branch to view the combustion light which is guided to a first bandpass filter, adapted to the common trunk end of the fiber. A portion of the light is reflected back through the common trunk portion of the fiber to a second bandpass filter adapted to the end of the other branch of the fiber. The first filter bandpass is centered at a wavelength corresponding to the emission line to be detected with a bandwidth of about three nanometers (nm). The second filter is centered at the same wavelength but having a width of about 10 nm. First and second light detectors are located to view the light passing through the first and second filters respectively. Thus, the second detector is blind to the light corresponding to the emission line of interest detected by the first detector and the difference between the two detector outputs is uniquely indicative of the intensity of only the combustion flame emission of interest. This instrument can reduce the effects of interfering blackbody radiation by greater than 20 dB.

  5. Optical emission line monitor with background observation and cancellation

    DOE Patents [OSTI]

    Goff, David R.; Notestein, John E.

    1986-01-01

    A fiber optics based optical emission line monitoring system is provided in which selected spectral emission lines, such as the sodium D-line emission in coal combustion, may be detected in the presence of interferring background or blackbody radiation with emissions much greater in intensity than that of the emission line being detected. A bifurcated fiber optic light guide is adapted at the end of one branch to view the combustion light which is guided to a first bandpass filter, adapted to the common trunk end of the fiber. A portion of the light is reflected back through the common trunk portion of the fiber to a second bandpass filter adapted to the end of the other branch of the fiber. The first filter bandpass is centered at a wavelength corresponding to the emission line to be detected with a bandwidth of about three nanometers (nm). The second filter is centered at the same wavelength but having a width of about 10 nm. First and second light detectors are located to view the light passing through the first and second filters respectively. Thus, the second detector is blind to the light corresponding to the emission line of interest detected by the first detector and the difference between the two detector outputs is uniquely indicative of the intensity of only the combustion flame emission of interest. This instrument can reduce the effects of interferring blackbody radiation by greater than 20 dB.

  6. The effect of bright lines in environmental risk communication

    SciTech Connect (OSTI)

    Wilson, K.N.; Desvousges, W.H.; Smith, K.V.; Payne, J. )

    1993-01-01

    Bright lines in environmental risk communication refer to the specific levels at which an environmental risk becomes a serious health threat and action should be taken to mitigate its effects. This study examined the effect of bright lines'' in risk communication by emphasizing the radon exposure threshold level of 4 picocuries per liter. Specifically, the authors developed a computer-assisted interview containing bright-line versions of risk information. The bright-line version contained a range of possible radon levels, the corresponding number of estimated lung cancer cases, the relative health risk from radon compared to other health risks, and the EPA guidelines for mitigating levels above 4 picocuries in the home. The non-bright line version was identical to the bright-line version, except it did not include the EPA's mitigation recommendations. Effect measures included respondents' change in perceived risk after reading their materials, intended testing behavior, and advice to their neighbor for a specified radon level either above or below the 4 picocury threshold level. This paper discusses broader policy implications for designing effective risk communication programs.

  7. Expression of low-, intermediate-, and high-affinity IL-2 receptors on B cell lines derived from patients with undifferentiated lymphoma of Burkitt's and non-Burkitt's types

    SciTech Connect (OSTI)

    Benjamin, D.; Rosolen, A.; Wormsley, S.B.; DeBault, L.E.; Colamonici, O.R. )

    1990-08-01

    IL-2 receptors on T cells exist in at least three forms which differ in their ligand-binding affinity. The low-affinity IL-2 receptor (IL-2R) consists of the 55-kDa Tac protein (p55 alpha), the intermediate-affinity site corresponds to the 70-kDa molecule (p70 beta), and the high-affinity IL-2R consists of a noncovalent heterodimeric structure involving both p55 alpha and p70 beta. We studied 24 B cell lines (8 EBV-negative and 16 EBV-positive) for IL-2R expression in the presence or absence of the tumor promoter, teleocidin. 125I-IL-2 radioreceptor binding assays and crosslinking studies demonstrated the sole expression of p55 alpha in EBV-negative cell lines only, whereas p55 alpha present in EBV-positive cell lines was always associated with p70 beta to construct high-affinity IL-2R. p70 beta was not detected in any of the EBV-negative cell lines, but was expressed on most of the EBV-positive cell lines (13 of 16). Our data also indicate that the expression of p55 alpha and p70 beta by radiolabeling correlates with their expression in flow cytometry, and that a large excess of p55 alpha is required to construct high-affinity IL-2R. Coexpression of p55 alpha and p70 beta on human B cells contributed to constructing high-affinity IL-2R hybrid complex as shown by rapid association rate contributed by p55 alpha and slow dissociation rate by p70 beta; teleocidin's ability to induce p55 alpha on cell lines which express p70 beta only, resulting in appearance of high-affinity IL-2R; and blocking p55 alpha by anti-Tac mAb in cell lines which constitutively express high-affinity IL-2R eliminated both high- and low-affinity components. The existence of low, intermediate, and high IL-2R on human B cells bears important future implications for understanding the mechanism of IL-2 signaling and the role of IL-2 in B cell activation, proliferation, and differentiation.

  8. Investigation Of In-Line Monitoring Options At H Canyon/HB Line For Plutonium Oxide Production

    SciTech Connect (OSTI)

    Sexton, L.

    2015-10-14

    H Canyon and HB Line have a production goal of 1 MT per year of plutonium oxide feedstock for the MOX facility by FY17 (AFS-2 mission). In order to meet this goal, steps will need to be taken to improve processing efficiency. One concept for achieving this goal is to implement in-line process monitoring at key measurement points within the facilities. In-line monitoring during operations has the potential to increase throughput and efficiency while reducing costs associated with laboratory sample analysis. In the work reported here, we mapped the plutonium oxide process, identified key measurement points, investigated alternate technologies that could be used for in-line analysis, and initiated a throughput benefit analysis.

  9. Discriminating binding mechanisms of an intrinsically disordered protein via a multi-state coarse-grained model

    SciTech Connect (OSTI)

    Knott, Michael [Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW (United Kingdom)] [Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW (United Kingdom); Best, Robert B., E-mail: robertbe@helix.nih.gov [Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW (United Kingdom); Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0520 (United States)

    2014-05-07

    Many proteins undergo a conformational transition upon binding to their cognate binding partner, with intrinsically disordered proteins (IDPs) providing an extreme example in which a folding transition occurs. However, it is often not clear whether this occurs via an induced fit or conformational selection mechanism, or via some intermediate scenario. In the first case, transient encounters with the binding partner favour transitions to the bound structure before the two proteins dissociate, while in the second the bound structure must be selected from a subset of unbound structures which are in the correct state for binding, because transient encounters of the incorrect conformation with the binding partner are most likely to result in dissociation. A particularly interesting situation involves those intrinsically disordered proteins which can bind to different binding partners in different conformations. We have devised a multi-state coarse-grained simulation model which is able to capture the binding of IDPs in alternate conformations, and by applying it to the binding of nuclear coactivator binding domain (NCBD) to either ACTR or IRF-3 we are able to determine the binding mechanism. By all measures, the binding of NCBD to either binding partner appears to occur via an induced fit mechanism. Nonetheless, we also show how a scenario closer to conformational selection could arise by choosing an alternative non-binding structure for NCBD.

  10. Distinct p53 genomic binding patterns in normal and cancer-derived human cells

    SciTech Connect (OSTI)

    Botcheva K.; McCorkle S. R.; McCombie W. R.; Dunn J. J.; Anderson C. W.

    2011-12-15

    We report here genome-wide analysis of the tumor suppressor p53 binding sites in normal human cells. 743 high-confidence ChIP-seq peaks representing putative genomic binding sites were identified in normal IMR90 fibroblasts using a reference chromatin sample. More than 40% were located within 2 kb of a transcription start site (TSS), a distribution similar to that documented for individually studied, functional p53 binding sites and, to date, not observed by previous p53 genome-wide studies. Nearly half of the high-confidence binding sites in the IMR90 cells reside in CpG islands, in marked contrast to sites reported in cancer-derived cells. The distinct genomic features of the IMR90 binding sites do not reflect a distinct preference for specific sequences, since the de novo developed p53 motif based on our study is similar to those reported by genome-wide studies of cancer cells. More likely, the different chromatin landscape in normal, compared with cancer-derived cells, influences p53 binding via modulating availability of the sites. We compared the IMR90 ChIPseq peaks to the recently published IMR90 methylome1 and demonstrated that they are enriched at hypomethylated DNA. Our study represents the first genome-wide, de novo mapping of p53 binding sites in normal human cells and reveals that p53 binding sites reside in distinct genomic landscapes in normal and cancer-derived human cells.

  11. Single Molecule Kinetics of ENTH Binding to Lipid Membranes

    SciTech Connect (OSTI)

    Rozovsky, Sharon; Forstner, Martin B.; Sondermann, Holger; Groves, Jay T.

    2012-04-03

    Transient recruitment of proteins to membranes is a fundamental mechanism by which the cell exerts spatial and temporal control over proteins’ localization and interactions. Thus, the specificity and the kinetics of peripheral proteins’ membrane residence are an attribute of their function. In this article, we describe the membrane interactions of the interfacial epsin N-terminal homology (ENTH) domain with its target lipid phosphatidylinositol (4,5)-bisphosphate (PtdIns(4,5)P2). The direct visualization and quantification of interactions of single ENTH molecules with supported lipid bilayers is achieved using total internal reflection fluorescence microscopy (TIRFM) with a time resolution of 13 ms. This enables the recording of the kinetic behavior of ENTH interacting with membranes with physiologically relevant concentrations of PtdIns(4,5)P2 despite the low effective binding affinity. Subsequent single fluorophore tracking permits us to build up distributions of residence times and to measure ENTH dissociation rates as a function of membrane composition. In addition, due to the high time resolution, we are able to resolve details of the motion of ENTH associated with a simple, homogeneous membrane. In this case ENTH’s diffusive transport appears to be the result of at least three different diffusion processes.

  12. Superlattices assembled through shape-induced directional binding

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lu, Fang; Yager, Kevin G.; Zhang, Yugang; Xin, Huolin; Gang, Oleg

    2015-04-23

    Organization of spherical particles into lattices is typically driven by packing considerations. Although the addition of directional binding can significantly broaden structural diversity, nanoscale implementation remains challenging. Here we investigate the assembly of clusters and lattices in which anisotropic polyhedral blocks coordinate isotropic spherical nanoparticles via shape-induced directional interactions facilitated by DNA recognition. We show that these polyhedral blocks—cubes and octahedrons—when mixed with spheres, promote the assembly of clusters with architecture determined by polyhedron symmetry. Moreover, three-dimensional binary superlattices are formed when DNA shells accommodate the shape disparity between nanoparticle interfaces. The crystallographic symmetry of assembled lattices is determined bymore » the spatial symmetry of the block’s facets, while structural order depends on DNA-tuned interactions and particle size ratio. Lastly, the presented lattice assembly strategy, exploiting shape for defining the global structure and DNA-mediation locally, opens novel possibilities for by-design fabrication of binary lattices.« less

  13. HB-Line Plutonium Oxide Data Collection Strategy

    SciTech Connect (OSTI)

    Watkins, R.; Varble, J.; Jordan, J.

    2015-05-26

    HB-Line and H-Canyon will handle and process plutonium material to produce plutonium oxide for feed to the Mixed Oxide Fuel Fabrication Facility (MFFF). However, the plutonium oxide product will not be transferred to the MFFF directly from HB-Line until it is packaged into a qualified DOE-STD-3013-2012 container. In the interim, HB-Line will load plutonium oxide into an inner, filtered can. The inner can will be placed in a filtered bag, which will be loaded into a filtered outer can. The outer can will be loaded into a certified 9975 with getter assembly in compliance with onsite transportation requirement, for subsequent storage and transfer to the K-Area Complex (KAC). After DOE-STD-3013-2012 container packaging capabilities are established, the product will be returned to HB-Line to be packaged into a qualified DOE-STD-3013-2012 container. To support the transfer of plutonium oxide to KAC and then eventually to MFFF, various material and packaging data will have to be collected and retained. In addition, data from initial HB-Line processing operations will be needed to support future DOE-STD-3013-2012 qualification as amended by the HB-Line DOE Standard equivalency. As production increases, the volume of data to collect will increase. The HB-Line data collected will be in the form of paper copies and electronic media. Paper copy data will, at a minimum, consist of facility procedures, nonconformance reports (NCRs), and DCS print outs. Electronic data will be in the form of Adobe portable document formats (PDFs). Collecting all the required data for each plutonium oxide can will be no small effort for HB-Line, and will become more challenging once the maximum annual oxide production throughput is achieved due to the sheer volume of data to be collected. The majority of the data collected will be in the form of facility procedures, DCS print outs, and laboratory results. To facilitate complete collection of this data, a traveler form will be developed which

  14. Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2)

    SciTech Connect (OSTI)

    Marr, Eric; Tardie, Mark; Carty, Maynard; Brown Phillips, Tracy; Wang, Ing-Kae; Soeller, Walt; Qiu, Xiayang Karam, George

    2006-11-01

    The crystal structure of human adipocyte lipid-binding protein (aP2) with a bound palmitate is reported at 1.5 resolution. Human adipocyte lipid-binding protein (aP2) belongs to a family of intracellular lipid-binding proteins involved in the transport and storage of lipids. Here, the crystal structure of human aP2 with a bound palmitate is described at 1.5 resolution. Unlike the known crystal structure of murine aP2 in complex with palmitate, this structure shows that the fatty acid is in a folded conformation and that the loop containing Phe57 acts as a lid to regulate ligand binding by excluding solvent exposure to the central binding cavity.

  15. rVISTA for Comparative Sequence-Based Discovery of Functional Transcription Factor Binding Sites

    SciTech Connect (OSTI)

    Loots, Gabriela G.; Ovcharenko, Ivan; Pachter, Lior; Dubchak, Inna; Rubin, Edward M.

    2002-03-08

    Identifying transcriptional regulatory elements represents a significant challenge in annotating the genomes of higher vertebrates. We have developed a computational tool, rVISTA, for high-throughput discovery of cis-regulatory elements that combines transcription factor binding site prediction and the analysis of inter-species sequence conservation. Here, we illustrate the ability of rVISTA to identify true transcription factor binding sites through the analysis of AP-1 and NFAT binding sites in the 1 Mb well-annotated cytokine gene cluster1 (Hs5q31; Mm11). The exploitation of orthologous human-mouse data set resulted in the elimination of 95 percent of the 38,000 binding sites predicted upon analysis of the human sequence alone, while it identified 87 percent of the experimentally verified binding sites in this region.

  16. Laboratory measurements of white dwarf photospheric spectral lines: Hβ

    SciTech Connect (OSTI)

    Falcon, Ross Edward; Rochau, Gregory A.; Bailey, James E.; Gomez, Thomas; Montgomery, Michael Houston; Winget, Donald E.; Nagayama, Taisuke

    2015-06-18

    We spectroscopically measure multiple hydrogen Balmer line profiles from laboratory plasmas to investigate the theoretical line profiles used in white dwarf (WD) atmosphere models. X-ray radiation produced at the Z Pulsed Power Facility at Sandia National Laboratories initiates plasma formation in a hydrogen-filled gas cell, replicating WD photospheric conditions. We also present time-resolved measurements of Hβ and fit this line using different theoretical line profiles to diagnose electron density, ne, and n = 2 level population, n2. Aided by synthetic tests, we characterize the validity of our diagnostic method for this experimental platform. During a single experiment, we infer a continuous range of electron densities increasing from ne ~ 4 to ~30 × 1016 cm-3 throughout a 120-ns evolution of our plasma. Also, we observe n2 to be initially elevated with respect to local thermodynamic equilibrium (LTE); it then equilibrates within ~55 ns to become consistent with LTE. This also supports our electron-temperature determination of Te ~ 1.3 eV (~15,000 K) after this time. At ne≲ 1017 cm-3, we find that computer-simulation-based line-profile calculations provide better fits (lower reduced χ2) than the line profiles currently used in the WD astronomy community. The inferred conditions, however, are in good quantitative agreement. Lastly, this work establishes an experimental foundation for the future investigation of relative shapes and strengths between different hydrogen Balmer lines.

  17. Laboratory Measurements of White Dwarf Photospheric Spectral Lines. Hβ

    SciTech Connect (OSTI)

    Falcon, Ross Edward; Rochau, Gregory A.; Bailey, James E.; Gomez, Thomas; Montgomery, Michael Houston; Winget, Donald E; Nagayama, Taisuke

    2015-06-18

    We spectroscopically measure multiple hydrogen Balmer line profiles from laboratory plasmas to investigate the theoretical line profiles used in white dwarf (WD) atmosphere models. X-ray radiation produced at the Z Pulsed Power Facility at Sandia National Laboratories initiates plasma formation in a hydrogen-filled gas cell, replicating WD photospheric conditions. We also present time-resolved measurements of Hβ and fit this line using different theoretical line profiles to diagnose electron density, ne, and n = 2 level population, n2. Aided by synthetic tests, we characterize the validity of our diagnostic method for this experimental platform. During a single experiment, we infer a continuous range of electron densities increasing from ne ~ 4 to ~30 × 1016 cm-3 throughout a 120-ns evolution of our plasma. Also, we observe n2 to be initially elevated with respect to local thermodynamic equilibrium (LTE); it then equilibrates within ~55 ns to become consistent with LTE. This also supports our electron-temperature determination of Te ~ 1.3 eV (~15,000 K) after this time. At ne≲ 1017 cm-3, we find that computer-simulation-based line-profile calculations provide better fits (lower reduced χ2) than the line profiles currently used in the WD astronomy community. The inferred conditions, however, are in good quantitative agreement. This work establishes an experimental foundation for the future investigation of relative shapes and strengths between different hydrogen Balmer lines.

  18. Position specific variation in the rate of evolution intranscription factor binding sites

    SciTech Connect (OSTI)

    Moses, Alan M.; Chiang, Derek Y.; Kellis, Manolis; Lander, EricS.; Eisen, Michael B.

    2003-08-28

    The binding sites of sequence specific transcription factors are an important and relatively well-understood class of functional non-coding DNAs. Although a wide variety of experimental and computational methods have been developed to characterize transcription factor binding sites, they remain difficult to identify. Comparison of non-coding DNA from related species has shown considerable promise in identifying these functional non-coding sequences, even though relatively little is known about their evolution. Here we analyze the genome sequences of the budding yeasts Saccharomyces cerevisiae, S. bayanus, S. paradoxus and S. mikataeto study the evolution of transcription factor binding sites. As expected, we find that both experimentally characterized and computationally predicted binding sites evolve slower than surrounding sequence, consistent with the hypothesis that they are under purifying selection. We also observe position-specific variation in the rate of evolution within binding sites. We find that the position-specific rate of evolution is positively correlated with degeneracy among binding sites within S. cerevisiae. We test theoretical predictions for the rate of evolution at positions where the base frequencies deviate from background due to purifying selection and find reasonable agreement with the observed rates of evolution. Finally, we show how the evolutionary characteristics of real binding motifs can be used to distinguish them from artifacts of computational motif finding algorithms. As has been observed for protein sequences, the rate of evolution in transcription factor binding sites varies with position, suggesting that some regions are under stronger functional constraint than others. This variation likely reflects the varying importance of different positions in the formation of the protein-DNA complex. The characterization of the pattern of evolution in known binding sites will likely contribute to the effective use of comparative

  19. Solution structure of telomere binding domain of AtTRB2 derived from Arabidopsis thaliana

    SciTech Connect (OSTI)

    Yun, Ji-Hye; Lee, Won Kyung; Kim, Heeyoun; Kim, Eunhee; Cheong, Chaejoon; Cho, Myeon Haeng; Lee, Weontae

    2014-09-26

    Highlights: • We have determined solution structure of Myb domain of AtTRB2. • The Myb domain of AtTRB2 is located in the N-terminal region. • The Myb domain of AtTRB2 binds to plant telomeric DNA without fourth helix. • Helix 2 and 3 of the Myb domain of AtTRB2 are involved in DNA recognition. • AtTRB2 is a novel protein distinguished from other known plant TBP. - Abstract: Telomere homeostasis is regulated by telomere-associated proteins, and the Myb domain is well conserved for telomere binding. AtTRB2 is a member of the SMH (Single-Myb-Histone)-like family in Arabidopsis thaliana, having an N-terminal Myb domain, which is responsible for DNA binding. The Myb domain of AtTRB2 contains three α-helices and loops for DNA binding, which is unusual given that other plant telomere-binding proteins have an additional fourth helix that is essential for DNA binding. To understand the structural role for telomeric DNA binding of AtTRB2, we determined the solution structure of the Myb domain of AtTRB2 (AtTRB2{sub 1–64}) using nuclear magnetic resonance (NMR) spectroscopy. In addition, the inter-molecular interaction between AtTRB2{sub 1–64} and telomeric DNA has been characterized by the electrophoretic mobility shift assay (EMSA) and NMR titration analyses for both plant (TTTAGGG)n and human (TTAGGG)n telomere sequences. Data revealed that Trp28, Arg29, and Val47 residues located in Helix 2 and Helix 3 are crucial for DNA binding, which are well conserved among other plant telomere binding proteins. We concluded that although AtTRB2 is devoid of the additional fourth helix in the Myb-extension domain, it is able to bind to plant telomeric repeat sequences as well as human telomeric repeat sequences.

  20. HIGH-n HYDROGEN RECOMBINATION LINES FROM THE FIRST GALAXIES

    SciTech Connect (OSTI)

    Rule, E.; Loeb, A.; Strelnitski, V. S.

    2013-09-20

    We investigate the prospects of blind and targeted searches in the radio domain (10 MHz to 1 THz) for high-n hydrogen recombination lines from the first generation of galaxies, at z ?< 10. The expected optically thin spontaneous ?-line luminosities are calculated as a function of the absolute AB magnitude of a galaxy at 1500 . For a blind search, semi-empirical luminosity functions are used to calculate the number of galaxies whose expected flux densities exceed an assumed detectability threshold. Plots of the minimum sky area, within which at least one detectable galaxy is expected at a given observing frequency, in the fiducial instantaneous passband of 10{sup 4} km s{sup 1}, allow us to assess the blind search time necessary for detection by a given facility. We show that the chances for detection are the highest in the millimeter and submillimeter domains, but finding spontaneous emission in a blind search, especially from redshifts z >> 1, is a challenge even with powerful facilities, such as the Actama Large Millimeter/Submillimeter Array and Square Kilometre Array. The probability of success is higher for a targeted search of lines with principal quantum number n ? 10 in Lyman-break galaxies amplified by gravitational lensing. Detection of more than one hydrogen line in such a galaxy will allow for line identification and a precise determination of the galaxy's redshift.

  1. Present state-of-the-art of transmission line icing

    SciTech Connect (OSTI)

    Pohlman, J.C.; Landers, P.

    1982-08-01

    Icing of overhead power lines is a serious problem for electric utilities. The loads resulting from iced conductors take many forms. Existing Codes and Guides offer little help in establishing adequate design criteria. Each transmission line designer must, therefore, rely heavily on intuitive judgment to set performance levels for transmission lines to be built within his particular service area. A special study was undertaken by author Pohlman in behalf of the Electric Power Research Institute (EPRI) to accomplish the following objectives: Improve the general understanding of the total problem; Sample utility perceptions and experience with the problem; Accumulate and review professional opinion on the subject; Inventory past and on-going research activities; Consolidate the above into a definition of the present state-of-the-art to define the need for future research.

  2. SSRL Beam Lines by Technique | Stanford Synchrotron Radiation Lightsource

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Beam Lines by Technique Beam Lines by Number | SPEAR3 Parameters Supported Technique(s) Beam Line X-ray Absorption Spectroscopy Biological x-ray absorption spectroscopy 2-2, 4-3, 7-3, 9-3, 14-3 Materials / catalysis / chemistry x-ray absorption spectroscopy 2-2, 4-1, 4-3, 11-2, 14-3 MEIS x-ray absorption spectroscopy 2-2, 4-1, 4-3, 11-2, 14-3 X-ray absorption spectroscopy imaging 2-2, 2-3, 6-2a, 10-2a,14-3 Single crystal x-ray absorption spectroscopy 9-3 Grazing incidence x-ray absorption

  3. Code System to Calculate Particle Penetration Through Aerosol Transport Lines.

    Energy Science and Technology Software Center (OSTI)

    1999-07-14

    Version 00 Distribution is restricted to US Government Agencies and Their Contractors Only. DEPOSITION1.03 is an interactive software program which was developed for the design and analysis of aerosol transport lines. Models are presented for calculating aerosol particle penetration through straight tubes of arbitrary orientation, inlets, and elbows. An expression to calculate effective depositional velocities of particles on tube walls is derived. The concept of maximum penetration is introduced, which is the maximum possible penetrationmore » through a sampling line connecting any two points in a three-dimensional space. A procedure to predict optimum tube diameter for an existing transport line is developed. Note that there is a discrepancy in this package which includes the DEPOSITION 1.03 executable and the DEPOSITION 2.0 report. RSICC was unable to obtain other executables or reports.« less

  4. Electric and magnetic field reduction by alternative transmission line options

    SciTech Connect (OSTI)

    Stewart, J.R. ); Dale, S.J. ); Klein, K.W. )

    1991-01-01

    Ground level electric, and more recently magnetic, fields from overhead power transmission lines are increasingly important considerations in right of way specification, with states setting or planning to set edge of right of way limits. Research has been conducted in high phase order power transmission wherein six of twelve phases are used to transmit power in less physical space and with reduced electrical environmental effects than conventional designs. The first magnetic field testing, as reported in this paper, has verified predictive methods for determination of magnetic fields from high phase order lines. Based on these analytical methods, field profiles have been determined for lines of different phase order of comparable power capacity. Potential advantages of high phase order as a means of field mitigation are discussed. 10 refs., 12 figs., 3 tabs.

  5. CONTINUOUS EXTRACTED BEAM IN THE AGS FAST EXTERNAL BEAM LINE.

    SciTech Connect (OSTI)

    GLENN,J.W.; TSOUPAS,N.; BROWN,K.A.; BIRYUKOV,V.M.

    2001-06-18

    A method to split off a few percent of the 6 x 10{sup 13} AGS beam delivered to the Slow External Beam (SEB) lines and send it down the Fast External Beam line (FEB) has been developed. The mission is to feed a counter experiment off the FEB that directly measures the neutrino mass using the muon storage ring. The use of normal thin septum splitters would have an excessive loss overhead and been optically difficult. The AGS Slow Extraction uses a third integer resonance with sextuple strength so the resonance width is a few percent of the beam width. This results in a low density tail which will be clipped by a bent crystal and deflected into the FEB channel. This clipping off of the tail should reduce losses in the SEB transport line. Details of modeled orbits, particle distribution and extraction trajectories into and out off the crystal will be given.

  6. LineVISAR. A fringe-trace data analysis program

    SciTech Connect (OSTI)

    Furnish, Michael D.

    2014-02-01

    The line-imaging ORVIS or VISAR provides velocity as a function of position and time for a line on an experimental setup via a streak camera record of interference fringes. This document describes a Matlab-based program which guides the user through the process of converting these fringe data to a velocity surface. The data reduction is of the "fringe trace" type, wherein the changes in velocity at a given position on the line are calculated based on fringe motion past that point. The analyst must establish the fringe behavior up front, aided by peak-finding routines in the program. However, the later work of using fringe jumps to compensate for phase problems in other analysis techniques is greatly reduced. This program is not a standard GUI construction, and is prescriptive. At various points it saves the progress, allowing later restarts from those points.

  7. NMR studies of DNA oligomers and their interactions with minor groove binding ligands

    SciTech Connect (OSTI)

    Fagan, P A

    1996-05-01

    The cationic peptide ligands distamycin and netropsin bind noncovalently to the minor groove of DNA. The binding site, orientation, stoichiometry, and qualitative affinity of distamycin binding to several short DNA oligomers were investigated by NMR spectroscopy. The oligomers studied contain A,T-rich or I,C-rich binding sites, where I = 2-desaminodeoxyguanosine. I{center_dot}C base pairs are functional analogs of A{center_dot}T base pairs in the minor groove. The different behaviors exhibited by distamycin and netropsin binding to various DNA sequences suggested that these ligands are sensitive probes of DNA structure. For sites of five or more base pairs, distamycin can form 1:1 or 2:1 ligand:DNA complexes. Cooperativity in distamycin binding is low in sites such as AAAAA which has narrow minor grooves, and is higher in sites with wider minor grooves such as ATATAT. The distamycin binding and base pair opening lifetimes of I,C-containing DNA oligomers suggest that the I,C minor groove is structurally different from the A,T minor groove. Molecules which direct chemistry to a specific DNA sequence could be used as antiviral compounds, diagnostic probes, or molecular biology tools. The author studied two ligands in which reactive groups were tethered to a distamycin to increase the sequence specificity of the reactive agent.

  8. Assessing Energetic Contributions to Binding from a Disordered Region in a Protein-Protein Interaction

    SciTech Connect (OSTI)

    S Cho; C Swaminathan; D Bonsor; M Kerzic; R Guan; J Yang; C Kieke; P Anderson; D Kranz; et al.

    2011-12-31

    Many functional proteins are at least partially disordered prior to binding. Although the structural transitions upon binding of disordered protein regions can influence the affinity and specificity of protein complexes, their precise energetic contributions to binding are unknown. Here, we use a model protein-protein interaction system in which a locally disordered region has been modified by directed evolution to quantitatively assess the thermodynamic and structural contributions to binding of disorder-to-order transitions. Through X-ray structure determination of the protein binding partners before and after complex formation and isothermal titration calorimetry of the interactions, we observe a correlation between protein ordering and binding affinity for complexes along this affinity maturation pathway. Additionally, we show that discrepancies between observed and calculated heat capacities based on buried surface area changes in the protein complexes can be explained largely by heat capacity changes that would result solely from folding the locally disordered region. Previously developed algorithms for predicting binding energies of protein-protein interactions, however, are unable to correctly model the energetic contributions of the structural transitions in our model system. While this highlights the shortcomings of current computational methods in modeling conformational flexibility, it suggests that the experimental methods used here could provide training sets of molecular interactions for improving these algorithms and further rationalizing molecular recognition in protein-protein interactions.

  9. Rapidity evolution of Wilson lines at the next-to-leading order

    SciTech Connect (OSTI)

    Balitsky, Ian; Chirilli, Giovanni

    2013-12-01

    At high energies particles move very fast so the proper degrees of freedom for the fast gluons moving along the straight lines are Wilson-line operators - infinite gauge factors ordered along the line. In the framework of operator expansion in Wilson lines the energy dependence of the amplitudes is determined by the rapidity evolution of Wilson lines. We present the next-to-leading order hierarchy of the evolution equations for Wilson-line operators.

  10. Letter from Deputy Secretary Poneman to Clean Line Energy Regarding the

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plains & Eastern Clean Line Project Under Section 1222 of EPAct 2005 (April 5, 2012) | Department of Energy Letter from Deputy Secretary Poneman to Clean Line Energy Regarding the Plains & Eastern Clean Line Project Under Section 1222 of EPAct 2005 (April 5, 2012) Letter from Deputy Secretary Poneman to Clean Line Energy Regarding the Plains & Eastern Clean Line Project Under Section 1222 of EPAct 2005 (April 5, 2012) Letter from Deputy Secretary Poneman to Clean Line Energy

  11. Plains & Eastern Clean Line Project Proposal for New or Upgraded

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transmission Line Projects Under Section 1222 of the Energy Policy Act of 2005 | Department of Energy Project Proposal for New or Upgraded Transmission Line Projects Under Section 1222 of the Energy Policy Act of 2005 Plains & Eastern Clean Line Project Proposal for New or Upgraded Transmission Line Projects Under Section 1222 of the Energy Policy Act of 2005 Plains & Eastern Clean Line Project Proposal for New or Upgraded Transmission Line Projects Under Section 1222 of the Energy

  12. Self-monitoring high voltage transmission line suspension insulator

    DOE Patents [OSTI]

    Stemler, Gary E.; Scott, Donald N.

    1981-01-01

    A high voltage transmission line suspension insulator (18 or 22) which monitors its own dielectric integrity. A dielectric rod (10) has one larger diameter end fitting attachable to a transmission line and another larger diameter end fitting attachable to a support tower. The rod is enclosed in a dielectric tube (14) which is hermetically sealed to the rod's end fittings such that a liquidtight space (20) is formed between the rod and the tube. A pressurized dielectric liquid is placed within that space. A discoloring dye placed within this space is used to detect the loss of the pressurized liquid.

  13. Conductor design for the VLHC transmission line magnet

    SciTech Connect (OSTI)

    Foster, G.W.; Kashikhin, V.; McAshan, M.; Mazur, P.O.; Piekarz, H.; Volk, J.T.; Walker, R.

    1999-03-01

    The transmission line magnet [1] is under development for the Very Large Hadron Collider (VLHC) at Fermilab with the expectation that it’s cost will be several times less (per Tesla-meter) than conventional superconducting magnets. It is a dual-aperture warm-iron superferric magnet built around an 80kA superconducting transmission line. The superconductor consists of 8 Rutherford (SSC Outer) cables in an Invar pipe jacket. The conductor design requirements and development program is described. A 100kA conductor test facility based on inductive coupling is described.

  14. Characterization Plan for Soils Around Drain Line PLA-100115

    SciTech Connect (OSTI)

    D. Shanklin

    2006-05-24

    This Characterization Plan supports the Hazardous Waste Management Act/Resource Conservation and Recovery Act (HWMA/RCRA) closure of soils that may have been contaminated by releases from drain line PLA-100115, located within the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory Site. The requirements to address the closure of soils contaminated by a potential release from this line in a characterization plan was identified in the "HWMA/RCRA Less Than 90-day Generator Closure Report for the VES-SFE-126."

  15. Cast-stone sectors for lining bends in pipework

    SciTech Connect (OSTI)

    Chechulin, V.A.; Novikov, A.I.; Karpov, V.M.; Sotnik, A.A.; Sedyshev, B.L.

    1987-03-01

    The authors disclose an efficient method for lining the bends of pipelines used to deliver coal dust to the burners of coal-fired power plants or to transport coal slurries in mining and preparation enterprises. The method consists of melting a wear-resistant silicate compound and casting it in the form of rings whose increased width on the outboard side accounts for the angle of the bend when the rings are installed consecutively inside the pipe. Enhanced service life estimations and cost benefit analyses are given for pipe bends thus lined in both of the above applications.

  16. Evaluation of Instrumentation and Dynamic Thermal Ratings for Overhead Lines

    SciTech Connect (OSTI)

    Phillips, A.

    2013-01-31

    In 2010, a project was initiated through a partnership between the Department of Energy (DOE) and the New York Power Authority (NYPA) to evaluate EPRI's rating technology and instrumentation that can be used to monitor the thermal states of transmission lines and provide the required real-time data for real-time rating calculations. The project included the installation and maintenance of various instruments at three 230 kV line sites in northern New York. The instruments were monitored, and data collection and rating calculations were performed for about a three year period.

  17. Phase Transitions above the Yrast Line in {sup 154}Dy

    SciTech Connect (OSTI)

    Ma, W. C.; Martin, V.; Khoo, T. L.; Lauritsen, T.; Egido, J. L.; Ahmad, I.; Bhattacharyya, P.; Carpenter, M. P.; Daly, P. J.; Grabowski, Z. W.

    2000-06-26

    Spectra of the E2 quasicontinuum {gamma} rays feeding different spin regions of the {sup 154}Dy yrast line have been extracted. These are compared with corresponding theoretical spectra obtained by numerical simulations based on temperature-dependent Hartree-Fock theory, with thermal shape fluctuations. In this manner, different regions of the spin-energy plane can be examined. The results support the predictions of a smeared-out phase transition at high spin above the yrast line. (c) 2000 The American Physical Society.

  18. EIS-0486: Plains & Eastern Clean Line Transmission Project

    Broader source: Energy.gov [DOE]

    This EIS will evaluate the potential environmental impacts of participating with Clean Line Energy Partners LLC (Clean Line) in the proposed Plains & Eastern Project. The proposed project would include an overhead ± 600 kilovolt (kV) high voltage direct current (HVDC) electric transmission system and associated facilities with the capacity to deliver approximately 3,500 megawatts (MW) primarily from renewable energy generation facilities in the Oklahoma Panhandle region to load-serving entities in the Mid-South and Southeast via an interconnection with the Tennessee Valley Authority (TVA).

  19. DOE Sustainability Reporting Open Line Help Call | Department of Energy

    Office of Environmental Management (EM)

    November 18, 2015 2:00PM to 3:00PM EST The Sustainability Performance Office (SPO) sponsors open line help calls to assist DOE sites and national laboratories with the annual sustainability reporting process. Representatives from the SPO will be available on the call to answer specific questions with respect to Site Sustainability Plans (SSP) and the Consolidated Energy Data Report (CEDR). The Open Line call will follow no set format. DOE personnel may call in to ask questions or listen in to

  20. DOE Sustainability Reporting Open Line Help Call | Department of Energy

    Office of Environmental Management (EM)

    October 14, 2015 2:00PM to 3:00PM EDT The Sustainability Performance Office (SPO) sponsors open line help calls to assist DOE sites and national laboratories with the annual sustainability reporting process. Representatives from the SPO will be available on the call to answer specific questions with respect to Site Sustainability Plans (SSP) and the Consolidated Energy Data Report (CEDR). The Open Line call will follow no set format. DOE personnel may call in to ask questions or listen in to

  1. Shape coexistence along the N=Z line

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Shape coexistence along the N=Z line Recoil Distance Method for knock-out reactions. NSCL/Köln plunger device The method Transition rates in N=Z 6 4 Ge 410(60) 620(210) 1.5(5) 14 610 406 NSCL: K. Starosta, IKP Köln: A.Dewald et al. PRL 99, 042503 (2007) CMU: M. Horoi 6 8 Se transition rate predictions Recoil Distance Method Doppler-Shift Attenuation Method E E Reactions for accessing nuclei along the 28<N=Z<50 line channel identification is the key REACTIONS stable beams TRIUMF unstable

  2. SiteLines Looks at NNSS Successes in 2011

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SiteLines Looks at NNSS Successes in 2011 It was a big year at the Nevada National Security Site (NNSS) for the Nevada Site Office and its contractors. From returning to nuclear operations at the Joint Actinide Shock Physics Experimental Research (JASPER) facility to the formation of the National Center for Nuclear Security to the implementation of Governance Reform, the NNSS had one of its most successful years in FY2011. Now, with its sights set on 2012, SiteLines takes a closer look at the

  3. Dynamic Line Rating Oncor Electric Delivery Smart Grid Program

    SciTech Connect (OSTI)

    Johnson, Justin; Smith, Cale; Young, Mike; Donohoo, Ken; Owen, Ross; Clark, Eddit; Espejo, Raul; Aivaliotis, Sandy; Stelmak, Ron; Mohr, Ron; Barba, Cristian; Gonzalez, Guillermo; Malkin, Stuart; Dimitrova, Vessela; Ragsdale, Gary; Mitchem, Sean; Jeirath, Nakul; Loomis, Joe; Trevino, Gerardo; Syracuse, Steve; Hurst, Neil; Mereness, Matt; Johnson, Chad; Bivens, Carrie

    2013-05-04

    Electric transmission lines are the lifeline of the electric utility industry, delivering its product from source to consumer. This critical infrastructure is often constrained such that there is inadequate capacity on existing transmission lines to efficiently deliver the power to meet demand in certain areas or to transport energy from high-generation areas to high-consumption regions. When this happens, the cost of the energy rises; more costly sources of power are used to meet the demand or the system operates less reliably. These economic impacts are known as congestion, and they can amount to substantial dollars for any time frame of reference: hour, day or year. There are several solutions to the transmission constraint problem, including: construction of new generation, construction of new transmission facilities, rebuilding and reconductoring of existing transmission assets, and Dynamic Line Rating (DLR). All of these options except DLR are capital intensive, have long lead times and often experience strong public and regulatory opposition. The Smart Grid Demonstration Program (SGDP) project co-funded by the Department of Energy (DOE) and Oncor Electric Delivery Company developed and deployed the most extensive and advanced DLR installation to demonstrate that DLR technology is capable of resolving many transmission capacity constraint problems with a system that is reliable, safe and very cost competitive. The SGDP DLR deployment is the first application of DLR technology to feed transmission line real-time dynamic ratings directly into the system operation’s State Estimator and load dispatch program, which optimizes the matching of generation with load demand on a security, reliability and economic basis. The integrated Dynamic Line Rating (iDLR)1 collects transmission line parameters at remote locations on the lines, calculates the real-time line rating based on the equivalent conductor temperature, ambient temperature and influence of wind and solar

  4. SunLine Transit Agency Fuel Cell Transit Bus: Fourth Evaluation...

    Energy Savers [EERE]

    Fourth Evaluation Report and Appendices SunLine Transit Agency Fuel Cell Transit Bus: Fourth Evaluation Report and Appendices This report describes operations at SunLine Transit ...

  5. DOE-HDBK-1114-98; Guide to Good Practices for Line and Training...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DOE HANDBOOK GUIDE TO GOOD PRACTICES FOR LINE AND TRAINING MANAGER ACTIVITIES U.S. ... Practices for Line and Training Manager Activities Related to Training and Qualification, ...

  6. EA-1972: Electric District 2 to Saguaro No. 2 Transmission Line...

    Energy Savers [EERE]

    2: Electric District 2 to Saguaro No. 2 Transmission Line Rebuild; Pinal County, Arizona EA-1972: Electric District 2 to Saguaro No. 2 Transmission Line Rebuild; Pinal County, ...

  7. New Tritium Source On Line at DOE's Savannah River Site | National...

    National Nuclear Security Administration (NNSA)

    Tritium Source On Line at DOE's Savannah River Site February 27, 2007 New Tritium Source On Line at DOE's Savannah River Site

  8. WAC - 468-34 - Utility Lines-Franchises and Permits | Open Energy...

    Open Energy Info (EERE)

    Lines-Franchises and PermitsLegal Abstract This section outlines the rules and procedures for granting franchises and permits for utility lines in the state. Published NA...

  9. Method for detecting binding events using micro-X-ray fluorescence spectrometry

    DOE Patents [OSTI]

    Warner, Benjamin P.; Havrilla, George J.; Mann, Grace

    2010-12-28

    Method for detecting binding events using micro-X-ray fluorescence spectrometry. Receptors are exposed to at least one potential binder and arrayed on a substrate support. Each member of the array is exposed to X-ray radiation. The magnitude of a detectable X-ray fluorescence signal for at least one element can be used to determine whether a binding event between a binder and a receptor has occurred, and can provide information related to the extent of binding between the binder and receptor.

  10. THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death

    SciTech Connect (OSTI)

    Balakrishnan, Meenakshi P.; Cilenti, Lucia; Ambivero, Camilla; Goto, Yamafumi; Takata, Minoru; Turkson, James; Li, Xiaoman Shawn; Zervos, Antonis S.

    2011-01-07

    Research highlights: {yields} THAP5 is a DNA-binding protein and a transcriptional repressor. {yields} THAP5 is induced in melanoma cells upon exposure to UV or treatment with cisplatin. {yields} THAP5 induction correlates with the degree of apoptosis in melanoma cell population. {yields} THAP5 is a pro-apoptotic protein involved in melanoma cell death. -- Abstract: THAP5 was originally isolated as a specific interactor and substrate of the mitochondrial pro-apoptotic Omi/HtrA2 protease. It is a human zinc finger protein characterized by a restricted pattern of expression and the lack of orthologs in mouse and rat. The biological function of THAP5 is unknown but our previous studies suggest it could regulate G2/M transition in kidney cells and could be involved in human cardiomyocyte cell death associated with coronary artery disease (CAD). In this report, we expanded our studies on the properties and function of THAP5 in human melanoma cells. THAP5 was expressed in primary human melanocytes as well as in all melanoma cell lines that were tested. THAP5 protein level was significantly induced by UV irradiation or cisplatin treatment, conditions known to cause DNA damage. The induction of THAP5 correlated with a significant increase in apoptotic cell death. In addition, we show that THAP5 is a nuclear protein that could recognize and bind a specific DNA motif. THAP5 could also repress the transcription of a reporter gene in a heterologous system. Our work suggests that THAP5 is a DNA-binding protein and a transcriptional repressor. Furthermore, THAP5 has a pro-apoptotic function and it was induced in melanoma cells under conditions that promoted cell death.

  11. The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

    SciTech Connect (OSTI)

    Gough, Mallory Blanthorn-Hazell, Sophee Delury, Craig Parkin, Edward

    2014-10-31

    Highlights: • Copper levels are elevated in the tumour microenvironment. • APP mitigates copper-induced growth inhibition of DU145 prostate cancer (PCa) cells. • The APP intracellular domain is a prerequisite; soluble forms have no effect. • The E1 CuBD of APP is also a prerequisite. • APP copper binding potentially mitigates copper-induced PCa cell growth inhibition. - Abstract: Copper plays an important role in the aetiology and growth of tumours and levels of the metal are increased in the serum and tumour tissue of patients affected by a range of cancers including prostate cancer (PCa). The molecular mechanisms that enable cancer cells to proliferate in the presence of elevated copper levels are, therefore, of key importance in our understanding of tumour growth progression. In the current study, we have examined the role played by the amyloid precursor protein (APP) in mitigating copper-induced growth inhibition of the PCa cell line, DU145. A range of APP molecular constructs were stably over-expressed in DU145 cells and their effects on cell proliferation in the presence of copper were monitored. Our results show that endogenous APP expression was induced by sub-toxic copper concentrations in DU145 cells and over-expression of the wild-type protein was able to mitigate copper-induced growth inhibition via a mechanism involving the cytosolic and E1 copper binding domains of the full-length protein. APP likely represents one of a range of copper binding proteins that PCa cells employ in order to ensure efficient proliferation despite elevated concentrations of the metal within the tumour microenvironment. Targeting the expression of such proteins may contribute to therapeutic strategies for the treatment of cancers.

  12. EA-1960: Townsite Solar Project Transmission Line, Clark County, Nevada

    Broader source: Energy.gov [DOE]

    The Bureau of Land Management, with Western Area Power Administration as a cooperating agency, prepared an EA to evaluate potential impacts of a proposal to build and operate a 180-MW photovoltaic facility; a 220, 230, or 500 kV transmission line; and associated facilities in Clark County, Nevada.

  13. EIS-0124: Conrad-Shelby Transmission Line Project, Montana

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy's Western Area Power Administration developed this statement to assess the environmental impact of adding a 230 kV transmission line between Conrad and Shelby, Montana and a new substation near Shelby to update the stressed electrical transmission system.

  14. EIS-0090: Fort Peck-Havre Transmission Line Project, Montana

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy’s Western Area Power Administration prepared this statement to assess the potential environmental and socioeconomic implications of its proposed action to construct and operate a 230kV transmission line from Fort Peck to Havre, Montana, with three intermediate interconnecting substations.

  15. Strengthening Line Management Oversight and Federal Monitoring of Nuclear Facilities

    Office of Environmental Management (EM)

    Strengthening Line Management Oversight and Federal Monitoring of Nuclear Facilities Standard Review Plan Volume 2 -- Nuclear Safety Basis Program Review During Design February 2015 i Standard Review Plan Volume 2 Nuclear Safety Basis Program Review during Design Facility Life Cycle Applicability CD-1 CD-2 CD-3 CD-4 Operations and Transitions Decommissioning & Environmental Restoration February 2015 ii Table of Contents Acronyms

  16. HIGH FREQUENCY POWER TRANSMISSION LINE FOR CYCLOTRONS AND THE LIKE

    DOE Patents [OSTI]

    Armstrong, W.J.

    1954-04-20

    High-frequency power transmission systems, particularly a stacked capacitance alternating power current transmission line wherein maximum utilization of the effective conductios skin of the line conductors is achieved while enabling a low impedance to be obtained are reported. The transmission line consists of a number of flat metal strips with interleaved dielectric strips. The metal dielectric strips are coiled spirally with the axis of the spiral extending along the length of the strips, and the alternating metal strips at the output end have outwardly extending aligned lugs which are directly strapped together and connected to the respective terminals on the load. At the input end of the transmission line, similarly, the alternate metal strips are directly strapped together and connected to an altereating current source. With the arrangement described each metal strip conducts on both sides, so that the metal strips are designed to have a thickness corresponding to twice the depth of the "skin effect" conducting lamina of each conductor at the source frequency.

  17. Operating Experience Level 3, Danger! Equipment Hits Overhead Lines

    Broader source: Energy.gov [DOE]

    OE-3 2016-01: This Operating Experience Level 3 (OE-3) document provides information about a safety concern related to workers and operations at Department of Energy (DOE) facilities where equipment has struck overhead communication cables and energized power lines.

  18. Rotating superconductor magnet for producing rotating lobed magnetic field lines

    DOE Patents [OSTI]

    Hilal, Sadek K.; Sampson, William B.; Leonard, Edward F.

    1978-01-01

    This invention provides a rotating superconductor magnet for producing a rotating lobed magnetic field, comprising a cryostat; a superconducting magnet in the cryostat having a collar for producing a lobed magnetic field having oppositely directed adjacent field lines; rotatable support means for selectively rotating the superconductor magnet; and means for energizing the superconductor magnet.

  19. QER- Comment of Clean Line Energy Partners LLC

    Broader source: Energy.gov [DOE]

    Hello, Clean Line Energy Partners would like to submit the attached written comments to the QER task force, in conjunction with the verbal comments Jimmy Glotfelty provided today in Newark. Thank you for your consideration, and please let us know if you would like any additional information. Sincerely, Diana Rivera

  20. Southern Asia future plans feature long-distance lines

    SciTech Connect (OSTI)

    Not Available

    1991-11-01

    This paper reports that although pipe line mileage working, planned and under study has dipped slightly from 47,346 km (29,420 mi) to 44,853 km (27,871 mi), Southern Asia continues to hold a strong position for future projects with some of the most interesting programs in the international market. Two dramatic, long-distance natural gas transmission, gathering and lateral networks continue to hold the future pipe line construction spotlight in Southern Asia. The Association of South East Asian Nations (ASEAN) continues to study a 7,830 km (4,865 mi) gas transmission system. With an estimated cost of $10 billion, the system includes some 6,276 km (3,900 mi) of transmission lines, with 1,094 km (680 mi) offshore. Group members include Brunei, Indonesia, Malaysia, the Philippines, Singapore and Thailand. The second project, the Trans-Asian Pipeline System, involves 3,380 km (2,100 mi) of transmission lines from the Iran's Bandar Abbas gas field across Pakistan to a terminal at Calcutta, India.

  1. DISCOVERY OF CARBON RADIO RECOMBINATION LINES IN M82

    SciTech Connect (OSTI)

    Morabito, Leah K.; Oonk, J. B. R.; Salgado, Francisco; Röttgering, H. J. A.; Tielens, A. G. G. M.; Haverkorn, Marijke; Toribio, M. Carmen; Heald, George; Beck, Rainer; Adebahr, Björn; Best, Philip; Beswick, Robert; Bonafede, Annalisa; Brüggen, Marcus; Brunetti, Gianfranco; Chyży, Krzysztof T.; Conway, J. E.; Horellou, Cathy; Van Driel, Wim; Gregson, Jonathan; and others

    2014-11-10

    Carbon radio recombination lines (RRLs) at low frequencies (≲ 500 MHz) trace the cold, diffuse phase of the interstellar medium, which is otherwise difficult to observe. We present the detection of carbon RRLs in absorption in M82 with the Low Frequency Array in the frequency range of 48-64 MHz. This is the first extragalactic detection of RRLs from a species other than hydrogen, and below 1 GHz. Since the carbon RRLs are not detected individually, we cross-correlated the observed spectrum with a template spectrum of carbon RRLs to determine a radial velocity of 219 km s{sup –1}. Using this radial velocity, we stack 22 carbon-α transitions from quantum levels n = 468-508 to achieve an 8.5σ detection. The absorption line profile exhibits a narrow feature with peak optical depth of 3 × 10{sup –3} and FWHM of 31 km s{sup –1}. Closer inspection suggests that the narrow feature is superimposed on a broad, shallow component. The total line profile appears to be correlated with the 21 cm H I line profile reconstructed from H I absorption in the direction of supernova remnants in the nucleus. The narrow width and centroid velocity of the feature suggests that it is associated with the nuclear starburst region. It is therefore likely that the carbon RRLs are associated with cold atomic gas in the direction of the nucleus of M82.

  2. 241-AY-102 Leak Detection Pit Drain Line Inspection Report

    SciTech Connect (OSTI)

    Boomer, Kayle D.; Engeman, Jason K.; Gunter, Jason R.; Joslyn, Cameron C.; Vazquez, Brandon J.; Venetz, Theodore J.; Garfield, John S.

    2014-01-20

    This document provides a description of the design components, operational approach, and results from the Tank AY-102 leak detection pit drain piping visual inspection. To perform this inspection a custom robotic crawler with a deployment device was designed, built, and operated by IHI Southwest Technologies, Inc. for WRPS to inspect the 6-inch leak detection pit drain line.

  3. SNOW LINES AS PROBES OF TURBULENT DIFFUSION IN PROTOPLANETARY DISKS

    SciTech Connect (OSTI)

    Owen, James E. [Canadian Institute for Theoretical Astrophysics, 60 St George Street, Toronto, M5S 3H8, ON (Canada)

    2014-07-20

    Sharp chemical discontinuities can occur in protoplanetary disks, particularly at ''snow lines'' where a gas-phase species freezes out to form ice grains. Such sharp discontinuities will diffuse out due to the turbulence suspected to drive angular momentum transport in accretion disks. We demonstrate that the concentration gradientin the vicinity of the snow lineof a species present outside a snow line but destroyed inside is strongly sensitive to the level of turbulent diffusion (provided the chemical and transport timescales are decoupled) and provides a direct measurement of the radial ''Schmidt number'' (the ratio of the angular momentum transport to radial turbulent diffusion). Taking as an example the tracer species N{sub 2}H{sup +}, which is expected to be destroyed inside the CO snow line (as recently observed in TW Hya) we show that ALMA observations possess significant angular resolution to constrain the Schmidt number. Since different turbulent driving mechanisms predict different Schmidt numbers, a direct measurement of the Schmidt number in accretion disks would allow inferences to be made about the nature of the turbulence.

  4. A Laser-Wire System at the ATF Extraction Line

    SciTech Connect (OSTI)

    Boogert, S.T.; Blair, G.; Boorman, G.; Bosco, A.; Deacon, L.; Driouichi, C.; Karataev, P.; /Royal Holloway, U. of London; Kamps, T.; /BESSY, Berlin; Delerue, N.; Dixit, S.; Foster, B.; Gannaway, F.; Howell, D.F.; Qureshi, M.; Reichold, A.; Senanayake, R.; /Oxford U.; Aryshev, A.; Hayano, H.; Kubo, K.; Terunuma, N.; Urakawa, J.; /KEK, Tsukuba /Liverpool

    2007-02-12

    A new laser-wire (LW) system has been installed at the ATF extraction line at KEK, Tsukuba. The system aims at a micron-scale laser spot size and employs a mode-locked laser system. The purpose-built interaction chamber, light delivery optics, and lens systems are described, and the first results are presented.

  5. Comments on RFI on Permitting of Transmission Lines Available

    Broader source: Energy.gov [DOE]

    The Department of Energy’s Office of Electricity Delivery and Energy Reliability released a Federal Register Notice seeking information on questions related to permitting of transmission lines. The Request for Information focused on making the development times for generation and transmission more commensurate with one another. Public comments received are now available for review and downloading.

  6. Federal Line Management Oversight of Department of Energy Nuclear Facilities

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2014-04-14

    The Guide was developed in support of DOE O 226.1B to provide guidance that may be useful to DOE line management organizations in meeting the provisions of that order when applied to nuclear facilities. Supersedes DOE G 226.1-2

  7. Safety and Health Regulatory and Policy Response Line- General Information

    Broader source: Energy.gov [DOE]

    The DOE Worker Safety and Health Standards Response Line, established in 1992, is a service that responds to questions DOE, DOE contractor, and DOE subcontractor personnel regarding DOE-adopted and -prescribed standards and directives. These responses may not represent official OSHA policies.

  8. High voltage gas insulated transmission line with continuous particle trapping

    DOE Patents [OSTI]

    Cookson, Alan H. (Pittsburgh, PA); Dale, Steinar J. (Monroeville, PA)

    1983-01-01

    This invention provides a novel high voltage gas insulated transmission line utilizing insulating supports spaced at intervals with snap-in means for supporting a continuous trapping apparatus and said trapping apparatus having perforations and cutouts to facilitate trapping of contaminating particles and system flexibility.

  9. Gamma ray lines from a universal extra dimension

    SciTech Connect (OSTI)

    Bertone, G.; Jackson, C. B.; Shaughnessy, G.; Tait, T. M.P.; Vallinotto, A.

    2012-03-01

    Indirect Dark Matter searches are based on the observation of secondary particles produced by the annihilation or decay of Dark Matter. Among them, gamma-rays are perhaps the most promising messengers, as they do not suffer deflection or absorption on Galactic scales, so their observation would directly reveal the position and the energy spectrum of the emitting source. Here, we study the detailed gamma-ray energy spectrum of Kaluza--Klein Dark Matter in a theory with 5 Universal Extra Dimensions. We focus in particular on the two body annihilation of Dark Matter particles into a photon and another particle, which produces monochromatic photons, resulting in a line in the energy spectrum of gamma rays. Previous calculations in the context of the five dimensional UED model have computed the line signal from annihilations into \\gamma \\gamma, but we extend these results to include \\gamma Z and \\gamma H final states. We find that these spectral lines are subdominant compared to the predicted \\gamma \\gamma signal, but they would be important as follow-up signals in the event of the observation of the \\gamma \\gamma line, in order to distinguish the 5d UED model from other theoretical scenarios.

  10. Replacement of alloy 800H superheated steam line

    SciTech Connect (OSTI)

    Barbier, R.A.; Bullock, J.W. [Sterling Chemicals, Texas City, TX (United States)

    1996-07-01

    Sterling Chemicals utilizes alloy 800HT (UNS N08811) piping for superheated steam service in its styrene dehydrogenation unit. An engineering project to replace these lines was recently completed. Material acquisition, shop fabrication, inspection requirements, and field erection will be highlighted in this paper.

  11. Selective Binding of O2 over N2 in a Redox-Active Metal-Organic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Selective Binding of O2 over N2 in a Redox-Active Metal-Organic Framework with Open Iron(II) Coordination Sites Previous Next List E. D. Bloch, L. J. Murray, W. L. Queen, S. ...

  12. De novo Design of an Artificial bis-[4Fe4S] Binding Protein

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    De novo Design of an Artificial bis-4Fe4S Binding Protein Authors: Roy, A,, Sarrou, I., Vaughn, M.D., Astashkin, A.V., and Ghirlanda, G. Title: De novo Design of an Artificial ...

  13. Investigation of the mode of binding of a novel series ofN-benzyl...

    Office of Scientific and Technical Information (OSTI)

    of the hepatitis C viral polymerase are described herein. These compounds bind to the hepatitis C virus non-structural protein 5B (NS5B), and co-crystal structures of select...

  14. Secondary PDZ domain-binding site on class B plexins enhances...

    Office of Scientific and Technical Information (OSTI)

    Title: Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF Authors: Pascoe, Heath G. ; Gutowski, Stephen ; Chen, Hua ; Brautigam, Chad A. ; ...

  15. New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities...

    Office of Scientific and Technical Information (OSTI)

    Title: New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins Authors: Zhang, Qi ; Fan, Lixin ; Hou, Feng ; Dong, Aiping ; Wang, Yun-Xing ; Tong, Yufeng ...

  16. Capture and release of acid-gasses with acid-gas binding organic compounds

    DOE Patents [OSTI]

    Heldebrant, David J; Yonker, Clement R; Koech, Phillip K

    2015-03-17

    A system and method for acid-gas capture wherein organic acid-gas capture materials form hetero-atom analogs of alkyl-carbonate when contacted with an acid gas. These organic-acid gas capture materials include combinations of a weak acid and a base, or zwitterionic liquids. This invention allows for reversible acid-gas binding to these organic binding materials thus allowing for the capture and release of one or more acid gases. These acid-gas binding organic compounds can be regenerated to release the captured acid gasses and enable these organic acid-gas binding materials to be reused. This enables transport of the liquid capture compounds and the release of the acid gases from the organic liquid with significant energy savings compared to current aqueous systems.

  17. Structure of Human Toll-like Receptor 3 (TLR3) Ligand-binding...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Human Toll-like Receptor 3 (TLR3) Ligand-binding Domain Jungwoo Choe1, Matthew S. Kelker1, ... Figure 1. Overall structure of human TLR3 ECD. The N-terminal region is colored blue, the ...

  18. THEORETICAL EVOLUTION OF OPTICAL STRONG LINES ACROSS COSMIC TIME

    SciTech Connect (OSTI)

    Kewley, Lisa J.; Dopita, Michael A.; Sutherland, Ralph; Leitherer, Claus; Dave, Romeel; Allen, Mark; Groves, Brent

    2013-09-10

    We use the chemical evolution predictions of cosmological hydrodynamic simulations with our latest theoretical stellar population synthesis, photoionization, and shock models to predict the strong line evolution of ensembles of galaxies from z = 3 to the present day. In this paper, we focus on the brightest optical emission-line ratios, [N II]/H{alpha} and [O III]/H{beta}. We use the optical diagnostic Baldwin-Phillips-Terlevich (BPT) diagram as a tool for investigating the spectral properties of ensembles of active galaxies. We use four redshift windows chosen to exploit new near-infrared multi-object spectrographs. We predict how the BPT diagram will appear in these four redshift windows given different sets of assumptions. We show that the position of star-forming galaxies on the BPT diagram traces the interstellar medium conditions and radiation field in galaxies at a given redshift. Galaxies containing active galactic nucleus (AGN) form a mixing sequence with purely star-forming galaxies. This mixing sequence may change dramatically with cosmic time, due to the metallicity sensitivity of the optical emission-lines. Furthermore, the position of the mixing sequence may probe metallicity gradients in galaxies as a function of redshift, depending on the size of the AGN narrow-line region. We apply our latest slow shock models for gas shocked by galactic-scale winds. We show that at high redshift, galactic wind shocks are clearly separated from AGN in line ratio space. Instead, shocks from galactic winds mimic high metallicity starburst galaxies. We discuss our models in the context of future large near-infrared spectroscopic surveys.

  19. U-038: BIND 9 Resolver crashes after logging an error in query.c

    Broader source: Energy.gov [DOE]

    A remote server can cause the target connected client to crash. Organizations across the Internet are reporting crashes interrupting service on BIND 9 nameservers performing recursive queries. Affected servers crash after logging an error in query.c with the following message: "INSIST(! dns_rdataset_isassociated(sigrdataset))" Multiple versions are reported as being affected, including all currently supported release versions of ISC BIND 9. ISC is actively investigating the root cause and working to produce patches which avoid the crash.

  20. U-039: ISC Update: BIND 9 Resolver crashes after logging an error in query.c

    Broader source: Energy.gov [DOE]

    A remote server can cause the target connected client to crash. Organizations across the Internet are reporting crashes interrupting service on BIND 9 nameservers performing recursive queries. Affected servers crash after logging an error in query.c with the following message: "INSIST(! dns_rdataset_isassociated(sigrdataset))" Multiple versions are reported as being affected, including all currently supported release versions of ISC BIND 9. ISC is actively investigating the root cause and working to produce patches which avoid the crash.