National Library of Energy BETA

Sample records for beta court reporting

  1. Atkinson-Baker Court Reporters

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    depo.com Atkinson-Baker Court Reporters 1 1 U.S. DEPARTMENT OF ENERGY 2 PUBLIC SCOPING MEETING 3 4 ENVIRONMENTAL ASSESSMENT FOR THE ACCEPTANCE AND 5 DISPOSITION OF USED NUCLEAR FUEL CONTAINING 6 U.S.-ORIGIN HIGHLY ENRICHED URANIUM 7 FROM THE FEDERAL REPUBLIC OF GERMANY 8 9 DATE: February 4, 2016 10 7:04 p.m. 11 North Augusta Community Center 12 495 Brookside Avenue 13 North Augusta, SC 29841 14 15 16 Holmes Brown, Facilitator 17 Maxcine Maxted, Department of Energy, EA Document Manager 18

  2. Project Reports for Lac Courte Oreilles Band of Lake Superior Chippewa Indians- 2007 Project

    Broader source: Energy.gov [DOE]

    The Lac Courte Oreilles Band of Lake Superior Chippewa will gather and compile information on the tribe's energy use, conduct energy audits of reservation facilities, identify where conservation efforts would be worthwhile, and evaluate policy changes needed to implement conservation measures.

  3. Genetics in the courts

    SciTech Connect (OSTI)

    Coyle, Heather; Drell, Dan

    2000-12-01

    Various: (1)TriState 2000 Genetics in the Courts (2) Growing impact of the new genetics on the courts (3)Human testing (4) Legal analysis - in re G.C. (5) Legal analysis - GM ''peanots'', and (6) Legal analysis for State vs Miller

  4. Structure, Stoichiometry and Stability in Magnetoplumbite and {beta}-Alumina Structured Type Ceramics. Final Report

    SciTech Connect (OSTI)

    Cormack, A. N.

    2004-03-01

    Work has been completed on the atomistic simulation of hexa-aluminate ceramics with the magnetoplumbite and beta-alumina type structures. In this report, three aspects of the work are highlighted. One is the simulation of surface structures. The second concerns details of the interstitially mechanisms observed in molecular dynamics simulations. The novel result here is the observation that the lattice ion always leaves its Beevers-Ross site before the aBR interstitial begins to move towards the lattice site. It is also found that, as expected, the interstitial mechanism is the most common mechanism in the heavily disordered nonstoichiometric structure, as well as in the stoichiometric material. Finally, the disposition of trivalent europium in the phosphor material BAM has been elucidated.

  5. Comparison of COMETHE-IIIJ and FCODE-BETA fission gas-release predictions with measurements. Final report. [PWR; BWR

    SciTech Connect (OSTI)

    Lee, S.; Rayes, L.; Rumble, E.; Wheeler, D.; Woods, A.

    1983-03-01

    This report describes a comparison of the Fission Product Gas Release (FGR) predictability of two LWR fuel rod modeling codes: COMETHE-IIIJ and FCODE-BETA. The comparison is made using 124 well characterized fuel rods with FGR measurements in the EPRI Fuel Performance Data Base.

  6. Experimental studies of the early effects of inhaled beta-emitting radionuclides for nuclear accident risk assessment: Phase 2 report

    SciTech Connect (OSTI)

    Scott, B.R.; Hahn, F.F.; Newton, G.J.; Snipes, M.B.; Damon, E.G.; Mauderly, J.L.; Boecker, B.B.; Gray, D.H.

    1987-11-01

    This report summarizes a series of experiments concerning the effect of linear energy transfer and temporal radiation dose pattern to the lung from inhaled beta-emitting radionuclides. The results were used to test the validity of a hazard-function mathematical model for predicting death from radiation pneumonitis. Both morbidity and mortality within 18 months after exposure were examined in rats exposed to beta-emitting radionuclides, giving brief or protracted irradiation of the lung or having weak or strong beta emissions. Protraction of the radiation dose to the lung from a half-time in the lung of less than three days to a half-time with a long-term component of about 150 days has a sparing effect. The median lethal dose for the protracted irradiation is about 1.7 times the median lethal dose for the brief irradiation. Low energy beta emissions from /sup 147/Pm have a similar effectiveness in producing lethal injury as high energy beta emissions from /sup 90/Sr. Changes in three parameters of morbidity were measured: body weight, hematology and pulmonary function; only changes in pulmonary function correlated well with pulmonary radiation injury. The doses of radiation required to produce impaired function, however, were not significantly different from those that produced death. The hazard-function model for predicting death from radiation pneumonitis, which was developed from previously obtained data for inhalation exposures of dogs to beta-emitting radionuclides, adequately predicted the median lethal doses for rats receiving one of several different beta dose rate patterns to the lung, thus strengthening the validity of the mathematical model. 23 refs., 41 figs., 12 tabs.

  7. Assessment of SPEAR-FCODE-BETA for fuel licensing. Final report. [PWR; BWR

    SciTech Connect (OSTI)

    Bradley, E.R.; Lanning, D.D.; Fiero, I.B.; Freeburn, H.R.; Garde, A.M.; Krammen, M.A.; Rotondo, P.L.

    1983-03-01

    The EPRI FCODE-BETA fuel performance code is the mechanistic model portion for the SPEAR-BETA fuel reliability code, which was developed for EPRI by Entropy Limited. FCODE-BETA was assessed by Battelle, Pacific Northwest Laboratories, and Combustion Engineering, Inc., for adequacy in simulating fuel performance in fuel licensing proceedings. The assessment included a detailed review of those thermal and mechanical performance models of greatest importance to fuel licensing, including fission gas release, fuel temperatures, and cladding uniform strain. It was concluded that the code is inadequate for licensing calculations in its present form. Recommendations for modeling and usability improvements are made.

  8. Colorado Water Courts | Open Energy Information

    Open Energy Info (EERE)

    Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Colorado Water Courts Abstract This is the website for Colorado Water Courts. Author Colorado...

  9. Doug MacCourt | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Doug MacCourt About Us Doug MacCourt - Senior Policy Advisor Doug MacCourt Doug MacCourt advises the DOE Office of Indian Energy's director and staff and works throughout DOE and with other federal and state agencies on policy, legislative, and funding issues that are critical to the Office's mission of developing and deploying clean energy and related economic development projects in Indian Country. Mr. MacCourt has more than 25 years of experience working with tribes, Alaska Native

  10. SPEAR-BETA fuel performance code system. Volume 1. General description. Final report. [BWR; PWR

    SciTech Connect (OSTI)

    Christensen, R.

    1982-04-01

    This document provides a general description of the SPEAR-BETA fuel reliability code system. Included is a discussion of the methodology employed and the structure of the code system, as well as discussion of the major components: the data preparation routines, the mechanistic fuel performance model, the mechanistic cladding failure model, and the statistical failure model.

  11. Beta Radiation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Beta Radiation 1. Beta radiation may travel meters in air and is moderately penetrating. 2. Beta radiation can penetrate human skin to the "germinal layer," where new skin cells...

  12. Sustaining the natural and economical resources of the Lac Courte Oreilles, Leslie Isham; Jason Weaver

    SciTech Connect (OSTI)

    Isham, Leslie; Weaver, Jason

    2013-09-30

    The Lac Courte Oreilles Band of Lake Superior Chippewa Indians, located in northwest Wisconsin has developed a project, entitled Sustaining the Natural and Economic Resources of the LCO Ojibwe. This technical report is a summary of the project.

  13. SPEAR-BETA fuel-performance code system: fission-gas-release module. Final report. [PWR; BWR

    SciTech Connect (OSTI)

    Christensen, R.

    1983-03-01

    The original SPEAR-BETA general description manual covers both mechanistic and statistical models for fuel reliability, but only mechanistic modeling of fission gas release. This addendum covers the SPEAR-BETA statistical model for fission gas release.

  14. Final Report for DUSEL R&D: BetaCage: A Screener of Ultra-Low-Level Radioactive Surface Contamination

    SciTech Connect (OSTI)

    Golwala, Sunil R.

    2013-12-20

    The eventual full-size, radiopure BetaCage will be a low-background, atmospheric-pressure neon drift chamber with unprecedented sensitivity to emitters of low-energy electrons and alpha particles. We expect that the prototype BetaCage already developed will be an excellent screener of alpha particles. Both the prototype and final BetaCage will provide new infrastructure for rare-event science.

  15. DOE Tour of Zero Floorplans: Chamberlain Court #75 by High Performance...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Chamberlain Court 75 by High Performance Homes DOE Tour of Zero Floorplans: Chamberlain Court 75 by High Performance Homes DOE Tour of Zero Floorplans: Chamberlain Court 75 by...

  16. Superfund awakes in state supreme courts

    SciTech Connect (OSTI)

    Sutherland, D.

    1998-01-01

    Superfund, often referred to as a sleeping giant, is waking up in state courts with rulings the insurance industry is on the hook for a large share of the nation`s environmental cleanup. While Congress has been quagmired in legislative reauthorization attempts, 40% of the state supreme courts (20 states) have passed laws favoring policyholders of comprehensive general liability insurance (CGL) to be compensated for their cleanup and litigation costs. These rulings vary in terms from state to state, but their collective action is giving the insurance industry grave concerns because of the increase in settlements with CGL policyholders.

  17. ARS 12 - Courts and Civil Proceedings | Open Energy Information

    Open Energy Info (EERE)

    ARS 12 - Courts and Civil Proceedings Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: ARS 12 - Courts and Civil ProceedingsLegal...

  18. Court decision dropping toxic substance rules stands

    SciTech Connect (OSTI)

    Bryant, C.R.

    1993-06-01

    In a somewhat surprising move, the U.S. Department of Labor has decided not to appeal a court decision essentially dropping regulations established by the Occupational Safety and Health Administration (OSHA) for about 400 hazardous substances. The decision leaves unregulated or subject to reduced standards substances that range from carbon monoxide to perchloroethylene. The Labor Department had until March 22, 1993, to appeal the court decision. On July 8, 1992, the U.S. Court of Appeals for the 11th Circuit overturned OSHA's final Air Contaminants Standard, which was promulgated in 1989. The standard established permissible exposure limits (PELs) for 428 toxic substances. In AFL-CIO vs. OSHA, the Court ruled that OSHA failed to make a separate scientific case for evaluating health risks of each chemical. Because of the decision not to appeal, PELs for more than half of the substances regulated by OSHA now are removed from the books or revert to the voluntary industry standards adopted by OSHA in 1970 and in force prior to the 1989 final rule.

  19. Lac Courte Oreilles Band of Lake Superior Ojibwe

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    below About Lac Courte Oreilles (LCO) Cont. * 2005 Tribal Governing Board adopted the Kyoto Protocol * 2006 Adopted the LCO Comprehensive Plan to provide 25% of the Tribes energy ...

  20. In addition, the court properly has jurisdiction over a counterclaim...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    specific questions. In response to the Court's remand order, Bonneville commenced this administrative process. On May 6, 2015, Bonneville issued a notice requesting public...

  1. Cape May Court House, New Jersey: Energy Resources | Open Energy...

    Open Energy Info (EERE)

    County, New Jersey.1 Registered Energy Companies in Cape May Court House, New Jersey Cap May County Municipal Utilities Authority References US Census Bureau 2005 Place to...

  2. DOE Tour of Zero Floorplans: Chamberlain Court #75 by High Performance

    Energy Savers [EERE]

    Homes | Department of Energy Chamberlain Court #75 by High Performance Homes DOE Tour of Zero Floorplans: Chamberlain Court #75 by High Performance Homes DOE Tour of Zero Floorplans: Chamberlain Court #75 by High Performance

  3. Double Beta Decay Experiments

    SciTech Connect (OSTI)

    Nanal, Vandana [Dept. of Nuclear and Atomic Physics, Tata Institute of Fundamental Research, Mumbai 400 005 (India)

    2011-11-23

    At present, neutrinoless double beta decay is perhaps the only experiment that can tell us whether the neutrino is a Dirac or a Majorana particle. Given the significance of the 0{nu}{beta}{beta}, there is a widespread interest for these rare event studies employing a variety of novel techniques. This paper describes the current status of DBD experiments. The Indian effort for an underground NDBD experiment at the upcoming INO laboratory is also presented.

  4. Rapid synthesis of beta zeolites

    DOE Patents [OSTI]

    Fan, Wei; Chang, Chun -Chih; Dornath, Paul; Wang, Zhuopeng

    2015-08-18

    The invention provides methods for rapidly synthesizing heteroatom containing zeolites including Sn-Beta, Si-Beta, Ti-Beta, Zr-Beta and Fe-Beta. The methods for synthesizing heteroatom zeolites include using well-crystalline zeolite crystals as seeds and using a fluoride-free, caustic medium in a seeded dry-gel conversion method. The Beta zeolite catalysts made by the methods of the invention catalyze both isomerization and dehydration reactions.

  5. Lac Courte Oreilles Hydro Dam Assessment

    SciTech Connect (OSTI)

    Weaver, Jason; Meyers, Amy

    2014-12-31

    The main objective of this project was to investigate upgrading the existing hydro power generating system at the Winter Dam. The tribe would like to produce more energy and receive a fair market power purchase agreement so the dam is no longer a drain on our budget but a contributor to our economy. We contracted Kiser Hydro, LLC Engineering for this project and received an engineering report that includes options for producing more energy with cost effective upgrades to the existing turbines. Included in this project was a negotiation of energy price sales negotiations.

  6. DOE PAGES Beta

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    portal to journal articles and accepted manuscripts resulting from DOE-funded research DOE PAGES Beta is the DOE response to the February 2013 White House Office of Science and...

  7. Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay

    Office of Scientific and Technical Information (OSTI)

    Experiment (Technical Report) | SciTech Connect Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay Experiment Citation Details In-Document Search Title: Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay Experiment Neutrinoless double beta decay searches play a major role in determining neutrino properties, in particular the Majorana or Dirac nature of the neutrino and the absolute scale of the neutrino mass. The consequences of these searches go

  8. U.S. District Court Upholds DOE's Action Against LG to Enforce ENERGY STAR

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Requirements | Department of Energy District Court Upholds DOE's Action Against LG to Enforce ENERGY STAR Requirements U.S. District Court Upholds DOE's Action Against LG to Enforce ENERGY STAR Requirements January 19, 2010 - 12:00am Addthis Washington, D.C. - On Monday, the United States District Court for the District of Columbia upheld the Department of Energy's decision to remove the ENERGY STAR® label from certain inefficient LG refrigerator-freezer models. As part of its expanded

  9. Level-2 Milestone 4468: Lorenz Simulation Interface Beta Release (Technical

    Office of Scientific and Technical Information (OSTI)

    Report) | SciTech Connect Level-2 Milestone 4468: Lorenz Simulation Interface Beta Release Citation Details In-Document Search Title: Level-2 Milestone 4468: Lorenz Simulation Interface Beta Release Authors: Long, J W ; Martinez, J J Publication Date: 2012-01-23 OSTI Identifier: 1093932 Report Number(s): LLNL-TR-525083 DOE Contract Number: W-7405-ENG-48 Resource Type: Technical Report Research Org: Lawrence Livermore National Laboratory (LLNL), Livermore, CA Sponsoring Org: USDOE Country of

  10. IO SUBSYSTEM 1 BETA

    Energy Science and Technology Software Center (OSTI)

    2002-08-21

    "IO Subsystem Ver. 1.0 Beta" uses standard object-oriented principles to minimize dependencies between the underlying input or output database format and the client code (i.e., Sierra) using the io subsystem. The interface and priciples are simolar to the Facade pattern described in the "Design Patterns" book by Gamma, et.al. The software uses data authentication algorithms to ensure data input/output is consistent with model being defined. "IO Subsystem Ver. 1.0 Beta" is a database independent input/outputmore » library for finite element analysis, preprocessing, post processing, and translation programs.« less

  11. Supreme court agrees: FERC must regulate wholesale markets

    SciTech Connect (OSTI)

    Wolak, Frank A.

    2008-08-15

    The author believes that wholesale markets in the United States would have a greater likelihood of ultimately benefiting consumers if the Federal Energy Regulatory Commission did not have the mandate under the Federal Power Act (FPA) to ensure that wholesale prices are ''just and reasonable.'' However, he continues to believe that the FERC cannot avoid having an ex post criteria for asssessing whether market prices are just and reasonable. Moreover, changes in the design and regulatory oversight of U.S. wholesale electricity markets in recent years, including the recent Supreme Court decision, have caused him to believe even more strongly in the guardrails-for-market-outcomes approach. Finally, several questions are addressed which relate to the pricing of fixed-price, long-term contracts and the impact of these obligations on the behavior of suppliers in short-term wholesale markets that are directly relevant to answering the two major questions that the Supreme Court remanded to FERC in its recent decision.

  12. Trichoderma .beta.-glucosidase

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2006-01-03

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  13. Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay

    Office of Scientific and Technical Information (OSTI)

    Experiment (Technical Report) | SciTech Connect Technical Report: Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay Experiment Citation Details In-Document Search Title: Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay Experiment × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided as a public service. Visit

  14. Double Beta Decay

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Double Beta Decay Measuring the Mass of the Neutrino One of the most elusive and exotic subatomic particles being investigated around the world today is the neutrino. Understanding the family of neutrino particles and how they interact with other matter (and among themselves) has become one the most intensive physics research efforts ever attempted by mankind. With a virtually undetectable mass, and without electric charge, these weakly interacting particles have been devilishly difficult to

  15. Beta* and beta-waist measurement and control at RHIC

    SciTech Connect (OSTI)

    Ptitsyn,V.; Della Penna, A.; Litvinenko, V.N.; Malitsky, N.; Satogata, T.

    2009-05-04

    During the course of last RHIC runs the beta-functions at the collision points ({beta}*) have been reduced gradually to 0.7m. In order to maximize the collision luminosity and ensure the agreement of the actual machine optics with the design one, more precise measurements and control of {beta}* value and {beta}-waist location became necessary. The paper presents the results of the implementation of the technique applied in last two RHIC runs. The technique is based on well-known relation between the tune shift and the beta function and involves precise betatron tune measurements using BBQ system as well as specially developed knobs for {beta}-waist location control.

  16. Solergy (Beta Version 1)

    Energy Science and Technology Software Center (OSTI)

    2009-03-30

    SOLERGY simulates the operation and power output of a user-defined solar central receiver power plant for a time period of up to one year. SOLERGY utilizes recorded or simulated weather data and plant component performance models to calculate the power flowing through each part of the solar plant. A plant control subroutine monitors these powers and determines when to operate the various plant subsystems. The original version of the code was released in May 1987,more » within SAND86-8060 and was widely distributed. The Beta Version 1 to be released in 2009, includes some relatively small modifications to the original code.« less

  17. BECCAV1.0 BETA

    Energy Science and Technology Software Center (OSTI)

    002318WKSTN00 Brain-Emulating Cognition and Control Architecture (BECCA) V1.0 beta http://sourceforge.net/projects/becca

  18. Simultaneous beta and gamma spectroscopy

    DOE Patents [OSTI]

    Farsoni, Abdollah T.; Hamby, David M.

    2010-03-23

    A phoswich radiation detector for simultaneous spectroscopy of beta rays and gamma rays includes three scintillators with different decay time characteristics. Two of the three scintillators are used for beta detection and the third scintillator is used for gamma detection. A pulse induced by an interaction of radiation with the detector is digitally analyzed to classify the type of event as beta, gamma, or unknown. A pulse is classified as a beta event if the pulse originated from just the first scintillator alone or from just the first and the second scintillator. A pulse from just the third scintillator is recorded as gamma event. Other pulses are rejected as unknown events.

  19. Court denies review of contractor/utility feud: contractors fear denial sets precedent

    SciTech Connect (OSTI)

    Poplett, J.

    1986-02-03

    On Jan. 27, the US Supreme Court refused to review a recent federal circuit court decision allowing a California public utility to enter into energy-related contractor activities; this may set a precedent for future related cases, according to an attorney for the contractor plaintiffs. The Supreme Court's refusal lets stand the 9th Federal Circuit Court of Appeals decision on Grason Electric Co. et al. vs. the Sacramento Municipal Utility District (SMUD). That decision allows SMUD - a public utility - to engage in energy-related businesses such as the installation of energy management systems and lighting retrofits, according to the attorney. The plaintiffs in the case, 13 electrical contractors in the Sacramento area, originally brought the case against SMUD on antitrust grounds because, they alleged, the utility was encroaching upon their businesses.

  20. Colorado - C.R.S. 40-6-115, Review by District Court | Open Energy...

    Open Energy Info (EERE)

    Colorado - C.R.S. 40-6-115, Review by District Court Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Colorado - C.R.S. 40-6-115,...

  1. I.C. 62-6 - Procedure Before Commission and in Courts | Open...

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: I.C. 62-6 - Procedure Before Commission and in CourtsLegal Abstract This statute governs...

  2. MAJORANA Neutrinoless Double-Beta Decay DUSEL R&D

    SciTech Connect (OSTI)

    Wilkerson, John F.

    2009-09-04

    The Majorana research and development is addressing key issues and risks related to the collaboration's goal of undertaking a search for neutrinoless double-beta decay (0{nu}{beta}{beta}) in {sup 76}Ge using an array of hyper-pure Ge-diodes (HPGe). The observation of this decay would provide critical insight into our understanding of neutrinos, yielding definitive evidence that neutrinos are Majorana particles and providing information on the absolute mass of neutrinos. Achieving sensitivities to 0{nu}{beta}{beta} decay half-lives on the order of 10{sup 26} years requires ultra-low backgrounds in the 2039 keV region where a 0{nu}{beta}{beta} decay peak would be observed. The goal of our R&D program has been to demonstrate the feasibility of all components of Majorana and to provide an integrated evaluation framework, allowing for optimization of these components in terms of background, background suppression, and signal detection efficiency and acceptance. This report covers work carried out by Majorana collaboration members at the University of Washington as part of the overall Majorana collaboration activities. Specifically the Majorana group at the University of Washington was involved in moving forward on demonstrating technology for clean large-scale cryostats and mounting the HPGe crystals in low-mass holders. The UW activities included assistance in the procurement and assembly of an electroforming system for large size cryostats, and design and fabrication of prototype crystal mounting hardware.

  3. 0{nu}{beta}{beta}: The experimental challenge

    SciTech Connect (OSTI)

    Ferroni, Fernando [Sapienza Universita' and INFN Sezione di Roma, Roma I-00185 (Italy)

    2010-11-24

    This paper describes the main experimental issues related to neutrinoless double beta decay searches. It discusses, although briefly, the past, present and future of this exciting, fundamental but extremely complex field of research.

  4. Variants of beta-glucosidases

    DOE Patents [OSTI]

    Fidantsef, Ana; Lamsa, Michael; Clancy, Brian Gorre

    2008-08-19

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  5. Variants of beta-glucosidase

    DOE Patents [OSTI]

    Fidantsef, Ana; Lamsa, Michael; Gorre-Clancy, Brian

    2015-07-14

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  6. Variants of beta-glucosidases

    DOE Patents [OSTI]

    Fidantsef, Ana; Lamsa, Michael; Gorre-Clancy, Brian

    2014-10-07

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  7. Variants of beta-glucosidase

    DOE Patents [OSTI]

    Fidantsef, Ana; Lamsa, Michael; Gorre-Clancy, Brian

    2009-12-29

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  8. Beta-gamma discriminator circuit

    SciTech Connect (OSTI)

    Erkkila, B.H.; Wolf, M.A.; Eisen, Y.; Unruh, W.P.; Brake, R.J.

    1984-01-01

    The major difficulty encountered in the determination of beta-ray dose in field conditions is generally the presence of a relatively high gamma-ray component. Conventional dosimetry instruments use a shield on the detector to estimate the gamma-ray component in comparison with the beta-ray component. More accurate dosimetry information can be obtained from the measured beta spectrum itself. At Los Alamos, a detector and discriminator circuit suitable for use in a portable spectrometer have been developed. This instrument will discriminate between gammas and betas in a mixed field. The portable package includes a 256-channel MCA which can be programmed to give a variety of outputs, including a spectral display, and may be programmed to read dose directly.

  9. Beta particle monitor for surfaces

    DOE Patents [OSTI]

    MacArthur, D.W.

    1997-10-21

    A beta radiation detector which is capable of reliably detecting beta radiation emitted from a surface. An electrically conductive signal collector is adjustably mounted inside an electrically conductive enclosure which may define a single large opening for placing against a surface. The adjustable mounting of the electrically conductive signal collector can be based on the distance from the surface or on the expected beta energy range. A voltage source is connected to the signal collector through an electrometer or other display means for creating an electric field between the signal collector and the enclosure. Air ions created by the beta radiation are collected and the current produced is indicated on the electrometer or other display means. 2 figs.

  10. EIA - Eia.gov BETA

    Gasoline and Diesel Fuel Update (EIA)

    EIA is currently analyzing the feedback and will be making changes to this web product as ... testing of EIA experimental web products: User feedback of beta products is moderated. ...

  11. Free boundary, high beta equilibrium in a large aspect ratio tokamak with

    Office of Scientific and Technical Information (OSTI)

    nearly circular plasma boundary (Technical Report) | SciTech Connect Free boundary, high beta equilibrium in a large aspect ratio tokamak with nearly circular plasma boundary Citation Details In-Document Search Title: Free boundary, high beta equilibrium in a large aspect ratio tokamak with nearly circular plasma boundary An analytic solution is obtained for free-boundary, high-beta equilibria in large aspect ratio tokamaks with a nearly circular plasma boundary. In the absence of surface

  12. Neutrinoless double beta decay and neutrino masses

    SciTech Connect (OSTI)

    Duerr, Michael [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany)

    2012-07-27

    Neutrinoless double beta decay (0{nu}{beta}{beta}) is a promising test for lepton number violating physics beyond the standard model (SM) of particle physics. There is a deep connection between this decay and the phenomenon of neutrino masses. In particular, we will discuss the relation between 0{nu}{beta}{beta} and Majorana neutrino masses provided by the so-called Schechter-Valle theorem in a quantitative way. Furthermore, we will present an experimental cross check to discriminate 0{nu}{beta}{beta} from unknown nuclear background using only one isotope, i.e., within one experiment.

  13. Lac Courte Oreilles Band of Lake Superior Chippewa Indians - Energy Analysis

    Energy Savers [EERE]

    Oreilles Band of Lake Superior Ojibwe Location of Lac Courte Oreilles About Lac Courte Oreilles (LCO) * The reservation is presently 76,465 acres and is 15 miles wide. * We have a seven member Tribal Governing Board with four year terms. * LCO's membership is about 7,000 with nearly half of its members residing on or near the reservation * There are 25 distinctly different communities within the reservation for a total of 1,019 households (2000 Census). * LCO operates two casinos; recently

  14. Fundamental processes in the interacting boson model: 0{nu}{beta}{beta} decay

    SciTech Connect (OSTI)

    Iachello, F. [Center for Theoretical Physics, Sloane Physics Laboratory, Yale University, New Haven, CT 06520-8120 (United States); Barea, J. [Departamento de Fisica, Universidad de Concepcion, Casilla 160-C, Concepcion (Chile)

    2011-05-06

    A program to calculate nuclear matrix elements for fundamental processes in the interacting boson model has been initiated. Results for the nuclear matrix elements in neutrinoless double beta decay 0{nu}{beta}{beta} are presented.

  15. Beta ray flux measuring device

    DOE Patents [OSTI]

    Impink, Jr., Albert J. (Murrysville, PA); Goldstein, Norman P. (Murrysville, PA)

    1990-01-01

    A beta ray flux measuring device in an activated member in-core instrumentation system for pressurized water reactors. The device includes collector rings positioned about an axis in the reactor's pressure boundary. Activated members such as hydroballs are positioned within respective ones of the collector rings. A response characteristic such as the current from or charge on a collector ring indicates the beta ray flux from the corresponding hydroball and is therefore a measure of the relative nuclear power level in the region of the reactor core corresponding to the specific exposed hydroball within the collector ring.

  16. BETA-GAMMA PERSONNEL DOSIMETER

    DOE Patents [OSTI]

    Davis, D.M.; Gupton, E.D.; Hart, J.C.; Hull, A.P.

    1961-01-17

    A personnel dosimeter is offered which is sensitive to both gamma and soft beta radiations from all directions within a hemisphere. The device is in the shape of a small pill box which is worn on a worker-s wrist. The top and sides of the device are provided with 50 per cent void areas to give 50 per cent response to the beta rays and complete response to the gamma rays. The device is so constructed as to have a response which will approximate the dose received by the basal layer of the human epidermis.

  17. Lac Courte Oreilles Band of Lake Superior Chippewa Indians- 2007 Project

    Broader source: Energy.gov [DOE]

    The Lac Courte Oreilles Band of Lake Superior Chippewa will gather and compile information on the tribe's energy use, conduct energy audits of reservation facilities, identify where conservation efforts would be worthwhile, and evaluate policy changes needed to implement conservation measures.

  18. New Limit on Time-Reversal Violation in Beta Decay

    SciTech Connect (OSTI)

    Mumm, H. P.; Chupp, T. E.; Cooper, R. L.; Coulter, K. P.; Freedman, S. J.; Fujikawa, B. K.; Garcia, A.; Jones, G. L.; Nico, J. S.; Thompson, A. K.; Trull, C. A.; Wietfeldt, F. E.; Wilkerson, J. F.

    2011-09-02

    We report the results of an improved determination of the triple correlation DP{center_dot}(p{sub e}xp{sub v}) that can be used to limit possible time-reversal invariance in the beta decay of polarized neutrons and constrain extensions to the standard model. Our result is D=[-0.96{+-}1.89(stat){+-}1.01(sys)]x10{sup -4}. The corresponding phase between g{sub A} and g{sub V} is {phi}{sub AV}=180.013 deg. {+-}0.028 deg. (68% confidence level). This result represents the most sensitive measurement of D in nuclear {beta} decay.

  19. SUTTIP V.0.1 BETA

    Energy Science and Technology Software Center (OSTI)

    002915WKSTN00 Sandia Unstructured Triangle Tabular Interpolation Package v 0.1 beta ihttps://software.sandia.gov/

  20. Polypeptides having beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same

    SciTech Connect (OSTI)

    Morant, Marc Dominique

    2014-05-06

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  1. Polypeptides having beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same

    DOE Patents [OSTI]

    Morant, Marc Dominique

    2014-04-29

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  2. Polypeptides having beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same

    DOE Patents [OSTI]

    Morant, Marc Dominique

    2014-05-06

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  3. Fact Sheet: Sodium-Beta Batteries (October 2012)

    Energy Savers [EERE]

    Sodium-Beta Batteries Improving the performance and reducing the cost of sodium-beta batteries for large-scale energy storage Sodium-beta batteries (Na-beta batteries or NBBs) use ...

  4. Characteristics of beta detection and dose measurement at Department of Energy facilities

    SciTech Connect (OSTI)

    Mulvehill, J.M.; Brackenbush, L.W.

    1987-02-01

    This report considers the current state of the art of beta dosimetry practices and beta detection methods used by health physicists at US Department of Energy facilities. This information is based on a survey of DOE facilities. Beta measurements are technically difficult and innovative efforts must be expended to improve their accuracy. Perhaps the most pronounced problem is that beta dosimetry and instrumentation in use are highly energy and angular dependent. Many believe that beta exposures are adequately controlled because beta to photon ratios are assumed to be low. This assumption is not always valid as demonstrated by the accident at Three Mile Island (TMI). Significant beta doses exist where personnel are exposed to mixed fission products; for example, chemical reprocessing plants, reactor accidents, or where uranium metals are processed. This report is part of an effort to increase the DOE response to this technically difficult area of health protection. Problem areas are addressed and methods recommended to improve beta dosimetry through a cooperative effort among the various DOE contractors. 34 refs., 2 figs., 16 tabs.

  5. Development of Cryogenic Bolometer for 0{nu}{beta}{beta} in {sup 124}Sn

    SciTech Connect (OSTI)

    Singh, Vivek; Mathimalar, S.; Dokania, Neha [INO, Tata Institute of Fundamental Research, Mumbai 400 005 (India); Yashwant, G.; Nanal, V.; Pillay, R. G. [Dept. of Nuclear and Atomic Physics, Tata Institute of Fundamental Research, Mumbai 400 005 (India); Datar, V. M. [Nuclear Physics Division, Bhabha Atomic Research Centre, Mumbai 400 085 (India)

    2011-11-23

    Cryogenic bolometer detectors, with their high resolution spectroscopy capability, are ideal for neutrino mass experiments as well as for search of rare processes like neutrinoless double beta decay (0{nu}{beta}{beta}) and dark matter. A feasibility study for investigation of 0{nu}{beta}{beta} in {sup 124}Sn at the upcoming underground facility of India based Neutrino Observatory (INO) has been initiated. This paper describes endeavors towards cryogenic tin bolometer development.

  6. 0v{beta}{beta} decay: theoretical nuclear matrix elements and their covariances

    SciTech Connect (OSTI)

    Lisi, Eligio [Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Via Orabona 4, 70126 Bari (Italy)

    2009-11-09

    Within the quasiparticle random phase approximation (QRPA), the covariances associated to the nuclear matrix elements (NME) of neutrinoless double beta decay (0v{beta}{beta}) are estimated. It is shown that correlated NME uncertainties play an important role in the comparison of 0v{beta}{beta} decay rates for different nuclei, both in the standard case of light Majorana neutrino exchange, and in nonstandard physics cases.

  7. EIA - Eia.gov BETA

    U.S. Energy Information Administration (EIA) Indexed Site

    Eia.gov BETA - U.S. Energy Information Administration (EIA) - U.S. Energy Information Administration (EIA) U.S. Energy Information Administration - EIA - Independent Statistics and Analysis Sources & Uses Petroleum & Other Liquids Crude oil, gasoline, heating oil, diesel, propane, and other liquids including biofuels and natural gas liquids. Natural Gas Exploration and reserves, storage, imports and exports, production, prices, sales. Electricity Sales, revenue and prices, power plants,

  8. IRS (Internal Revenue Service) claim against oil firms heads for a court showdown

    SciTech Connect (OSTI)

    Not Available

    1990-09-24

    During the gasoline crisis of the late Seventies, Saudi Arabia pumped oil to four U.S. oil companies at a price mutually agreed on. But the Internal Revenue Service says the companies sold the oil at a higher rate, raking in profits that they must pay taxes on. Exxon and Texaco dispute the ruling, while the other companies are being audited. The Tax Court is scheduled to try the case April of 1991.

  9. Project Reports for Lac Courte Oreilles Band of Lake Superior Chippewa Indians- 2010 Project

    Broader source: Energy.gov [DOE]

    The feasibility study of hydropower will answer three questions: 1) How can hydropower be developed to create a sustainable economic stream that contributes to the financial viability of the tribe? 2) How can this venture meet the energy needs of the community? 3) How can hydropower be developed without jeopardizing Mother Earth or the cultural beliefs of the tribe?

  10. Project Reports for Lac Courte Oreilles Band of Lake Superior Chippewa Indians- 2010 Project

    Broader source: Energy.gov [DOE]

    This weatherization training will result in a reduction of the use and cost of energy by increasing the number of homes that are weatherized.

  11. Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reports Reports Individual Permit reports are prepared annually to facilitate public review of activities for the previous year. Contact Environmental Communication & Public Involvement P.O. Box 1663 MS M996 Los Alamos, NM 87545 (505) 667-0216 Email Individual Permit for Storm Water Reports Annual Report 2015 (pdf) 2014 (pdf) 2013 (pdf) Submittal Letter (pdf) 2012 (pdf) Submittal Letter (pdf) 2011 (pdf) Background Metals and Radioactivity Report Background Metals Concentrations and

  12. Imperfect World of beta beta-decay Nuclear Data Sets

    SciTech Connect (OSTI)

    Pritychenko, B.

    2015-01-03

    The precision of double-beta ??-decay experimental half lives and their uncertainties is reanalyzed. The method of Benford's distributions has been applied to nuclear reaction, structure and decay data sets. First-digit distribution trend for ??-decay T2v1/2 is consistent with large nuclear reaction and structure data sets and provides validation of experimental half-lives. A complementary analysis of the decay uncertainties indicates deficiencies due to small size of statistical samples, and incomplete collection of experimental information. Further experimental and theoretical efforts would lead toward more precise values of-decay half-lives and nuclear matrix elements.

  13. Beta

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Best of 2013: Our Favorites from Photo of the Week Best of 2013: Our Favorites from Photo of the Week January 2, 2014 - 11:09am Addthis Controlling Chaos with Magnetic Fields 1 of 12 Controlling Chaos with Magnetic Fields This artistic rendition of "spin vortices" illustrates tiny magnetic vortices that spin according to the polarization of each disk's vortex core. At Argonne National Laboratory, scientists are using alternating magnetic fields to control the behavior of these spin

  14. Method for preparing Pb-. beta. ''-alumina ceramic

    DOE Patents [OSTI]

    Hellstrom, E.E.

    1984-08-30

    A process is disclosed for preparing impermeable, polycrystalline samples of Pb-..beta..''-alumina ceramic from Na-..beta..''-alumina ceramic by ion exchange. The process comprises two steps. The first step is a high-temperature vapor phase exchange of Na by K, followed by substitution of Pb for K by immersing the sample in a molten Pb salt bath. The result is a polycrystalline Pb-..beta..''-alumina ceramic that is substantially crack-free.

  15. Observation of Two-Neutrino Double-Beta Decay in Xe-136 with EXO-200

    Office of Scientific and Technical Information (OSTI)

    (Journal Article) | SciTech Connect Observation of Two-Neutrino Double-Beta Decay in Xe-136 with EXO-200 Citation Details In-Document Search Title: Observation of Two-Neutrino Double-Beta Decay in Xe-136 with EXO-200 We report the observation of two-neutrino double-beta decay in {sup 136}Xe with T{sub 1/2} = 2.11 {+-} 0.04(stat) {+-} 0.21(syst) x 10{sup 21} yr. This second-order process, predicted by the standard model, has been observed for several nuclei but not for {sup 136}Xe. The

  16. BECCA V0.1 BETA

    Energy Science and Technology Software Center (OSTI)

    002399MLTPL00 Brain-Emulating Cognition and Control Architecture (BECCA) v. 0.2 beta http://becca.sourceforge.net

  17. Beta cell device using icosahedral boride compounds

    DOE Patents [OSTI]

    Aselage, Terrence L.; Emin, David

    2002-01-01

    A beta cell for converting beta-particle energies into electrical energy having a semiconductor junction that incorporates an icosahedral boride compound selected from B.sub.12 As.sub.2, B.sub.12 P.sub.2, elemental boron having an .alpha.-rhombohedral structure, elemental boron having a .beta.-rhombohedral structure, and boron carbides of the chemical formula B.sub.12-x C.sub.3-x, where 0.15beta radiation source, and means for transmitting electrical energy to an outside load. The icosahedral boride compound self-heals, resisting degradation from radiation damage.

  18. The nuclear matrix elements for neutrinoless double beta decay

    SciTech Connect (OSTI)

    Simkovic, Fedor [Department of Nuclear Physics and Biophysics, Comenius University, Mlynska dolina, SK-84248 Bratislava (Slovakia)

    2007-10-12

    The status of calculation of the neutrinoless double beta decay (0{nu}{beta}{beta}-decay) nuclear matrix elements (NME's) is reviewed. The spread of published values of NME's is discussed. The main attention is paid to the recent progress achieved in the evaluation of the 0{nu}{beta}{beta}-decay NME's in the framework of the quasiparticle random phase approximation (QRPA). The obtained results are compared with those of the nuclear shell model. The problem of reliable determination of the 0{nu}{beta}{beta}-decay NME's is addressed. The uncertainty in NME's are analyzed and further progress in calculation of the 0{nu}{beta}{beta}-decay NME's is outlined.

  19. Neutrinoless double beta decay and nuclear matrix elements

    SciTech Connect (OSTI)

    Simkovic, Fedor [BLTP, JINR Dubna, 141980 Dubna, Moscow region (Russian Federation); Comenius University, Mlynska dolina, Bratislava (Slovakia)

    2011-11-23

    The fundamental importance of searching for neutrinoless double-beta decay (0{nu}{beta}{beta}-decay) is widely recognized. Observation of the decay would tell us that the total lepton number is not conserved and that, consequently, neutrinos are massive Majorana fermions. The 0{nu}{beta}{beta}-decay is discussed in context of neutrino oscillation data. The perspectives of the experimental 0{nu}{beta}{beta}-decay searches are analyzed. The importance of reliable determination of the 0{nu}{beta}{beta}-decay nuclear matrix elements is pointed out.

  20. Status of the MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-Beta

    Office of Scientific and Technical Information (OSTI)

    Decay (Conference) | SciTech Connect Status of the MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-Beta Decay Citation Details In-Document Search Title: Status of the MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-Beta Decay Authors: Efremenko, Yuri [1] ; Rielage, Keith Robert [2] ; Goett, John Jerome III [2] ; Elliott, Steven Ray [2] ; Xu, Wenqin [2] + Show Author Affiliations ORNL Los Alamos National Laboratory Publication Date: 2015-04-06 OSTI Identifier: 1177540 Report

  1. Gamma-ray blind beta particle probe

    DOE Patents [OSTI]

    Weisenberger, Andrew G.

    2001-01-01

    An intra-operative beta particle probe is provided by placing a suitable photomultiplier tube (PMT), micro channel plate (MCP) or other electron multiplier device within a vacuum housing equipped with: 1) an appropriate beta particle permeable window; and 2) electron detection circuitry. Beta particles emitted in the immediate vicinity of the probe window will be received by the electron multiplier device and amplified to produce a detectable signal. Such a device is useful as a gamma insensitive, intra-operative, beta particle probe in surgeries where the patient has been injected with a beta emitting radiopharmaceutical. The method of use of such a device is also described, as is a position sensitive such device.

  2. Process for reducing beta activity in uranium

    DOE Patents [OSTI]

    Briggs, G.G.; Kato, T.R.; Schonegg, E.

    1985-04-11

    This invention is a method for lowering the beta radiation hazards associated with the casting of uranium. The method reduces the beta radiation emitted from the as-cast surfaces of uranium ingots. The method also reduces the amount of beta radiation emitters retained on the interiors of the crucibles that have been used to melt the uranium charges and which undergone cleaning in a remote handling facility. The lowering of the radioactivity is done by scavenging the beta emitters from the molten uranium with a molten mixture containing the fluorides of magnesium and calcium. The method provides a means of collection and disposal of the beta emitters in a manner that reduces radiation exposure to operating personnel in the work area where the ingots are cast and processed. 5 tabs.

  3. Process for reducing beta activity in uranium

    DOE Patents [OSTI]

    Briggs, Gifford G.; Kato, Takeo R.; Schonegg, Edward

    1986-01-01

    This invention is a method for lowering the beta radiation hazards associated with the casting of uranium. The method reduces the beta radiation emitted from the as-cast surfaces of uranium ingots. The method also reduces the amount of beta radiation emitters retained on the interiors of the crucibles that have been used to melt the uranium charges and which have undergone cleaning in a remote handling facility. The lowering of the radioactivity is done by scavenging the beta emitters from the molten uranium with a molten mixture containing the fluorides of magnesium and calcium. The method provides a means of collection and disposal of the beta emitters in a manner that reduces radiation exposure to operating personnel in the work area where the ingots are cast and processed.

  4. Results from the Cuoricino (Zero-Neutrino Double Beta) Decay Experiment

    SciTech Connect (OSTI)

    Arnaboldi, C; Artusa, D R; Avignone, F T; Balata, M; Bandac, I; Barucci, M; Beeman, J W; Bellini, F; Brofferio, C; Bucci, C; Capelli, S; Carbone, L; Cebrian, S; Clemenza, M; Cremonesi, O; Creswick, R J; de Ward, A; Didomizio, S D; Dolinski, M J; Farach, H A; Fiorini, E; Frossati, G; Giachero, A; Giuliani, A; Gorla, P; Guardincerri, E; Gutierrez, T D; Haller, E E; Maruyama, R H; McDonald, R J; Nisi, S; Nones, C; Norman, E B; Nucciotti, A; Olivieri, E; Pallavicini, M; Palmieri, E; Pasca, E; Pavan, M; Pedretti, M; Pessina, G; Pirro, S; Previtali, E; Risegari, L; Rosenfeld, C; Sangiorgio, S; Sisti, M; Smith, A R; Torres, L; Ventura, G; Vignati, M

    2007-12-20

    Recent results from the CUORICINO {sup 130}Te zero-neutrino double-beta (0v{beta}{beta}) decay experiment are reported. CUORICINO is an array of 62 tellurium oxide (TeO{sub 2}) bolometers with an active mass of 40.7 kg. It is cooled to {approx}8 mK by a dilution refrigerator shielded from environmental radioactivity and energetic neutrons. It is running in the Laboratori Nazionali del Gran Sasso (LNGS) in Assergi, Italy. These data represent 11.83 kg y or 90.77 mole-years of {sup 130}Te. No evidence for 0v{beta}{beta}-decay was observed and a limit of T{sub 1/2}{sup 0v} ({sup 130}Te) {ge} 3.0 x 10{sup 24} y (90% C.L.) is set. This corresponds to upper limits on the effective mass, , between 0.19 and 0.68eV when analyzed with the many published nuclear structure calculations. In the context of these nuclear models, the values fall within the range corresponding to the claim of evidence of 0v{beta}{beta}-decay by H.V. Klapdor-Kleingrothaus and his co-workers. The experiment continues to acquire data.

  5. Interactions of Plakoglobin and [beta]-Catenin with Desmosomal Cadherins

    Office of Scientific and Technical Information (OSTI)

    BASIS OF SELECTIVE EXCLUSION OF [alpha]- AND [beta]-CATENIN FROM DESMOSOMES (Journal Article) | SciTech Connect Interactions of Plakoglobin and [beta]-Catenin with Desmosomal Cadherins BASIS OF SELECTIVE EXCLUSION OF [alpha]- AND [beta]-CATENIN FROM DESMOSOMES Citation Details In-Document Search Title: Interactions of Plakoglobin and [beta]-Catenin with Desmosomal Cadherins BASIS OF SELECTIVE EXCLUSION OF [alpha]- AND [beta]-CATENIN FROM DESMOSOMES Plakoglobin and {beta}-catenin are

  6. Majorana DUSEL R&D Final Report

    SciTech Connect (OSTI)

    Fast, James E.; Hoppe, Eric W.; Mintzer, Esther E.; Aalseth, Craig E.; Day, Anthony R.; Gerlach, David C.; Farmer, Orville T.; Liezers, Martin; Lepel, Elwood A.; Miley, Harry S.; Edwards, Danny J.

    2010-09-21

    This report summarizes the work performed at PNNL under the project Majorana Neutrinoless Double Beta Decay DUSEL R&D over the period of FY07-FY09.

  7. SciTech Connect: "neutrinoless double beta decay"

    Office of Scientific and Technical Information (OSTI)

    neutrinoless double beta decay" Find + Advanced Search Term Search Semantic Search Advanced Search All Fields: "neutrinoless double beta decay" Semantic Semantic Term Title:...

  8. tan{beta}-enhanced supersymmetric corrections to the anomalous magnetic moment of the muon

    SciTech Connect (OSTI)

    Marchetti, Schedar; Mertens, Susanne; Nierste, Ulrich; Stoeckinger, Dominik

    2009-01-01

    We report on a two-loop supersymmetric contribution to the magnetic moment (g-2){sub {mu}} of the muon which is enhanced by two powers of tan{beta}. This contribution arises from a shift in the relation between the muon mass and Yukawa coupling and can increase the supersymmetric contribution to (g-2){sub {mu}} sizably. As a result, if the currently observed 3{sigma} deviation between the experimental and SM theory value of (g-2){sub {mu}} is analyzed within the minimal supersymmetric standard model (MSSM), the derived constraints on the parameter space are modified significantly: If (g-2){sub {mu}} is used to determine tan{beta} as a function of the other MSSM parameters, our corrections decrease tan{beta} by roughly 10% for tan{beta}=50.

  9. Method for treating beta-spodumene ceramics

    DOE Patents [OSTI]

    Day, J. Paul; Hickman, David L.

    1994-09-27

    A vapor-phase method for treating a beta-spodumene ceramic article to achieve a substitution of exchangeable hydrogen ions for the lithium present in the beta-spodumene crystals, wherein a barrier between the ceramic article and the source of exchangeable hydrogen ions is maintained in order to prevent lithium contamination of the hydrogen ion source and to generate highly recoverable lithium salts, is provided.

  10. Beta/alpha continuous air monitor

    DOE Patents [OSTI]

    Becker, Gregory K.; Martz, Dowell E.

    1989-01-01

    A single deep layer silicon detector in combination with a microcomputer, recording both alpha and beta activity and the energy of each pulse, distinguishing energy peaks using a novel curve fitting technique to reduce the natural alpha counts in the energy region where plutonium and other transuranic alpha emitters are present, and using a novel algorithm to strip out radon daughter contribution to actual beta counts.

  11. Beta/alpha continuous air monitor

    DOE Patents [OSTI]

    Becker, G.K.; Martz, D.E.

    1988-06-27

    A single deep layer silicon detector in combination with a microcomputer, recording both alpha and beta activity and the energy of each pulse, distinquishing energy peaks using a novel curve fitting technique to reduce the natural alpha counts in the energy region where plutonium and other transuranic alpha emitters are present, and using a novel algorithm to strip out radon daughter contribution to actual beta counts. 7 figs.

  12. REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DOE/NV/11718-387 ECOLOGICAL MONITORING AND COMPLIANCE PROGRAM FISCAL YEAR 1999 REPORT December 1999 Prepared by Ecological Services P.O. Box 98521 Las Vegas, NV 89193-8521 DISCLAIMER STATEMENT Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise, does not necessarily constitute or imply its endorsement, recommendation, or favoring by the U.S. Government or any agency thereof or its contractors or subcontractors.

  13. Polypeptides having beta-glucosidase activity and polynucleotides encoding same

    SciTech Connect (OSTI)

    Morant, Marc Dominique

    2014-10-14

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  14. Insider Alert 1.0 Beta Version

    Energy Science and Technology Software Center (OSTI)

    2004-02-01

    Insider Alert 1.0 Beta Version supports interactive selection and graphical display of data generated by the Sandia Cognitive Framework, which simulates the examination of security data by experts of various specialties. Insider Alert also encompasses the configuration and data files input to the Cognitive Framework for this application. Insider Alert 1.0 Beta Version is a computer program for analyzing data indicative of possible espionage or improper handling of data by employees at Sandia National Laboratoriesmore » (or other facilities with comparable policies and procedures for managing sensitive information) It prioritizes and displays information for review by security analysts.« less

  15. Method of producing .beta.-spodumene bodies

    DOE Patents [OSTI]

    Chyung, Kenneth (Painted Post, NY); Day, J. Paul (Big Flats, NY); Holleran, Louis M. (Big Flats, NY); Olszewski, Anthony R. (Bath, NY)

    1999-01-01

    Beta-spodumene bodies and method of preparing the bodies that involves providing a uniform plastic batch of inorganic raw materials, organic binder, and vehicle, wherein the inorganic raw materials are composed of, in percent by weight, about 75% to 95% minerals, and about 5% to 25% glass. The batch is formed into a green body that is fired to produce a body composed substantially of beta-spodumene, and having a thermal expansion coefficient of <10.times.10.sup.-7 /.degree.C.(0-800.degree. C.), and a strength of .gtoreq.4 Ksi.

  16. The double-beta decay: Theoretical challenges

    SciTech Connect (OSTI)

    Horoi, Mihai

    2012-11-20

    Neutrinoless double beta decay is a unique process that could reveal physics beyond the Standard Model of particle physics namely, if observed, it would prove that neutrinos are Majorana particles. In addition, it could provide information regarding the neutrino masses and their hierarchy, provided that reliable nuclear matrix elements can be obtained. The two neutrino double beta decay is an associate process that is allowed by the Standard Model, and it was observed for about ten nuclei. The present contribution gives a brief review of the theoretical challenges associated with these two process, emphasizing the reliable calculation of the associated nuclear matrix elements.

  17. A ton-scale bolometric detector for the search for neutrinoless double beta decay

    SciTech Connect (OSTI)

    Pedretti, M. [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 (United States)

    2009-12-16

    After an introduction on neutrinoless double beta decay physics, a description of CUORE and CUORICINO experiments, detectors and results are reported. The actual efforts and next steps of the CUORE Project, required to probe the inverted hierarchy region of the neutrino effective Majorana mass, are also described.

  18. Report of the Committee on antitrust

    SciTech Connect (OSTI)

    Not Available

    1994-01-01

    This report of the Committee on Antitrust summarizes certain energy industry cases brought under the federal antitrust laws (i.e., Sherman Act, Clayton Act, Robinson-Patman Act) for the prior three years. This report also summarizes several significant Supreme Court decisions concerning the antitrust laws during this period. These cases did not involve energy matters, but they may have a significant bearing on antitrust situations involving energy companies.

  19. HIA 2015 DOE Zero Energy Ready Home Case Study: High Performance Homes, Chamberlain Court #75, Gettysburg, PA

    Energy Savers [EERE]

    Performance Homes Chamberlain Court #75 Gettysburg, PA DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are

  20. {beta} decay spectroscopy of {sup 192}Pt and the nature of 0{sup +} excitations.

    SciTech Connect (OSTI)

    McCutchan, E. A.; Casten, R. F.; Werner, V.; Winkler, R.; Cakirli, R. B.; Gurdal, G.; Liang, X.; Williams, E.; Physics; Yale Univ.; Istanbul Univ.; Clark Univ.; Univ.of Paisley

    2008-07-01

    Excited states in {sup 192}Pt were populated in {beta}{sup +}/{epsilon} decay and studied through off-beam {gamma}-ray spectroscopy. New coincidence data give no support for several reported low-energy, low-spin states proposed in {beta} decay and lead to a substantially revised level scheme. The structure of {sup 192}Pt is discussed in terms of both single-space IBA-1 calculations and two-space IBA calculations with configuration mixing. Both models together suggest that it is the perhaps the 04{sup +} state that corresponds to an intruder excitation, resulting from the excitation of a pair of protons across the Z=82 closed shell.

  1. Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting Mode and

    Office of Scientific and Technical Information (OSTI)

    Searching for Majoron-Emitting Modes (Thesis/Dissertation) | SciTech Connect Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting Mode and Searching for Majoron-Emitting Modes Citation Details In-Document Search Title: Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting Mode and Searching for Majoron-Emitting Modes Authors: Herrin, Steven ; /Stanford U., Phys. Dept. /SLAC Publication Date: 2013-08-23 OSTI Identifier: 1091528 Report Number(s): SLAC-R-1034 DOE Contract

  2. Ultrafast Dynamic Response of Single Crystal PETN and Beta-HMX (Conference)

    Office of Scientific and Technical Information (OSTI)

    | SciTech Connect Conference: Ultrafast Dynamic Response of Single Crystal PETN and Beta-HMX Citation Details In-Document Search Title: Ultrafast Dynamic Response of Single Crystal PETN and Beta-HMX Authors: Zaug, J M ; Armstrong, M R ; Crowhurst, J C ; Feranti, L ; Swan, R ; Gross, R ; Teshlich, N E ; Wall, M ; Austin, R A ; Fried, L E Publication Date: 2014-06-30 OSTI Identifier: 1149550 Report Number(s): LLNL-CONF-656341 DOE Contract Number: DE-AC52-07NA27344 Resource Type: Conference

  3. Effects of plasma {beta} on the plasmoid instability

    SciTech Connect (OSTI)

    Ni Lei; Ziegler, Udo; Huang Yimin; Lin Jun; Mei Zhixing

    2012-07-15

    The effects of the initial upstream plasma {beta} on the plasmoid instability are studied via two-dimensional resistive magnetohydrodynamic simulations. For cases with nonuniform {beta} dependent initial plasma mass density and uniform temperature, our numerical results indicate that the critical Lundquist number for onset of the plasmoid instability depends on the initial plasma {beta}. The critical Lundquist number is approximately 2000-3000 for {beta}=50 and is 8000-10 000 for {beta}=0.2. The higher the {beta}, the smaller the critical Lundquist number is. Similar to previous studies of high-{beta} systems, the average reconnection rate in low {beta} systems is found to become weakly dependent on the Lundquist number in the plasmoid-unstable regime. However, the average reconnection rate, normalized to the asymptotic value of upstream BV{sub A}, is lower in a low {beta} system than that in a high {beta} system. The magnetic energy spectral index, which characterizes fragmentation of the reconnection layer, is approximately two and is insensitive to {beta} in the high-Lunquist number regime. It is also found that the magnetic reconnection rate becomes similar for different {beta} cases, if the initial force-balance is provided by temperature gradient instead of density gradient. Therefore, it is concluded that the {beta}-dependence mentioned above may be largely attributed to the density variation.

  4. Tevatron low-beta quadrupole triplet interconnects

    SciTech Connect (OSTI)

    Oleck, A.R.; Carson, J.A.; Koepke, K.; Sorenson, D.

    1992-04-01

    Installation of cold iron quadrupole magnets in the Low Beta (Superconducting High-Luminosity) upgrade at Fermilab required a newly designed magnet interconnect. The interconnect design and construction experience is presented. Considered are the connections carrying cryogenic fluids, beam vacuum, insulating vacuum, superconducting bus leads, their insulation and mechanical support. Details of the assembly and assembly experience are presented. 2 refs.

  5. .beta.-glucosidase 5 (BGL5) compositions

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2010-06-01

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant BGL5 proteins and methods for producing the same.

  6. Sensitivity of CUORE to Neutrinoless Double-Beta Decay (Journal...

    Office of Scientific and Technical Information (OSTI)

    Sensitivity of CUORE to Neutrinoless Double-Beta Decay Citation Details In-Document Search Title: Sensitivity of CUORE to Neutrinoless Double-Beta Decay In this paper, we study the...

  7. Sensitivity of CUORE to Neutrinoless Double-Beta Decay (Journal...

    Office of Scientific and Technical Information (OSTI)

    Sensitivity of CUORE to Neutrinoless Double-Beta Decay Citation Details In-Document Search Title: Sensitivity of CUORE to Neutrinoless Double-Beta Decay You are accessing a...

  8. Nonaqueous actinide hydride dissolution and production of actinide $beta$- diketonates

    DOE Patents [OSTI]

    Crisler, L.R.

    1975-11-11

    Actinide beta-diketonate complex molecular compounds are produced by reacting a beta-diketone compound with a hydride of the actinide material in a mixture of carbon tetrachloride and methanol. (auth)

  9. He II Ly{beta} GUNN-PETERSON ABSORPTION: NEW HST OBSERVATIONS AND THEORETICAL EXPECTATIONS

    SciTech Connect (OSTI)

    Syphers, David; Pieri, Matthew; Shull, J. Michael; Anderson, Scott F.; Zheng, Wei; Kriss, Gerard A.; Smith, Britton; Meiksin, Avery; Schneider, Donald P.; York, Donald G.

    2011-12-01

    Observations of He II Ly{alpha} Gunn-Peterson troughs have proved to be a valuable probe of the epoch of helium reionization at z {approx} 3. Since this optical depth can become unmeasurably large even for modest He II fractions, various alternate techniques have been proposed to push to higher redshift, and among the more promising is looking at higher-order Lyman-series troughs. We here report four new observations of the He II Ly{beta} trough, including new data on the only sightline with a prior Ly{beta} observation. However, the effective optical depth ratio {tau}{sub eff,{beta}}/{tau}{sub eff,{alpha}} is not simply predicted by f{sub {beta}}{lambda}{sub {beta}}/f{sub {alpha}}{lambda}{sub {alpha}} = 0.16, and we analyze cosmological simulations to find that the correct ratio for helium at z {approx} 3 is {approx_equal}0.35. In one case we infer {tau}{sub eff,{alpha}} > 8.8, strong evidence that helium was not fully reionized at z = 3.2-3.5, in agreement with previous measurements suggesting a later completion of reionization.

  10. Y-12 Beta-3 Racetracks | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Y-12 Beta-3 Racetracks Y-12 Beta-3 Racetracks Y-12 Beta-3 Racetracks Built near the northeastern end of the Oak Ridge reservation, the Y-12 facility used the electromagnetic method to separate uranium-235 from the uranium-238 in natural uranium. During the Manhattan Project, Y-12 housed nine Alpha and eight Beta racetracks, which were arrangements of huge electromagnets containing a number of calutrons in the magnets' gaps. The calutrons sent a stream of charged particles through the magnetic

  11. Peroxisome proliferator-activated receptor {gamma} is expressed in hippocampal neurons and its activation prevents {beta}-amyloid neurodegeneration: role of Wnt signaling

    SciTech Connect (OSTI)

    Inestrosa, Nibaldo C. . E-mail: ninestr@genes.bio.puc.cl; Godoy, Juan A.; Quintanilla, Rodrigo A.; Koenig, Cecilia S.; Bronfman, Miguel

    2005-03-10

    The molecular pathogenesis of Alzheimer's disease (AD) involves the participation of the amyloid-{beta}-peptide (A{beta}), which plays a critical role in the neurodegeneration that triggers the disease. Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors, which are members of the nuclear receptor family. We report here that (1) PPAR{gamma} is present in rat hippocampal neurons in culture. (2) Activation of PPAR{gamma} by troglitazone and rosiglitazone protects rat hippocampal neurons against A{beta}-induced neurodegeneration, as shown by the 3-[4,5 -2yl]-2,5-diphenyltetrazolium bromide (MTT) reduction assay, immunofluorescence using an anti-heavy neurofilament antibody, and quantitative electron microscopy. (3) Hippocampal neurons treated with several PPAR{gamma} agonists, including troglitazone, rosiglitazone, and ciglitazone, prevent the excitotoxic A{beta}-induced rise in bulk-free Ca{sup 2+}. (4) PPAR{gamma} activation results in the modulation of Wnt signaling components, including the inhibition of glycogen synthase kinase-3{beta} (GSK-3{beta}) and an increase of the cytoplasmic and nuclear {beta}-catenin levels. We conclude that the activation of PPAR{gamma} prevents A{beta}-induced neurodegeneration by a mechanism that may involve a cross talk between neuronal PPAR{gamma} and the Wnt signaling pathway. More important, the fact that the activation of PPAR{gamma} attenuated A{beta}-dependent neurodegeneration opens the possibility to fight AD from a new therapeutic perspective.

  12. Method for conversion of .beta.-hydroxy carbonyl compounds

    DOE Patents [OSTI]

    Lilga, Michael A. (Richland, WA); White, James F. (Richland, WA); Holladay, Johnathan E. (Kennewick, WA); Zacher, Alan H. (Kennewick, WA); Muzatko, Danielle S. (Kennewick, WA); Orth, Rick J. (Kennewick, WA)

    2010-03-30

    A process is disclosed for conversion of salts of .beta.-hydroxy carbonyl compounds forming useful conversion products including, e.g., .alpha.,.beta.-unsaturated carbonyl compounds and/or salts of .alpha.,.beta.-unsaturated carbonyl compounds. Conversion products find use, e.g., as feedstock and/or end-use chemicals.

  13. Neutrinoless double-{beta} decay: Status and future

    SciTech Connect (OSTI)

    Bilenky, S. M. [Joint Institute for Nuclear Research (Russian Federation)], E-mail: bilenky@he.sissa.it

    2006-12-15

    A brief summary of the status of neutrino masses, mixing, and oscillations is presented. Neutrinoless double {beta} decay is considered. Predictions for the effective Majorana mass are reviewed. A possible test of the calculations of nuclear matrix elements of the 0{nu}{beta}{beta} decay is proposed.

  14. Polypeptides having beta-glucosidase activity and polynucleotides encoding same

    SciTech Connect (OSTI)

    Morant, Marc

    2014-01-14

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase, or beta-glucosidase activity and isolated polynucleotides encoding polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  15. The GERDA Neutrinoless Double Beta-Decay Experiment

    SciTech Connect (OSTI)

    Majorovits, Bela A. [Max Planck Institut fuer Physik, Foehringer Ring 6, 80805 Munich (Germany)

    2007-10-12

    Neutrinoless double beta (0{nu}{beta}{beta})-decay is the key process to gain understanding of the nature of neutrinos. The GErmanium Detector Array (GERDA) is designed to search for 0{nu}{beta}{beta}-decay of the isotope {sup 76}Ge. Germanium crystals enriched in {sup 76}Ge, acting as source and detector simultaneously, will be submerged directly into an ultra pure cooling medium that also serves as a radiation shield. This concept will allow for a reduction of the background by up to two orders of magnitudes with respect to earlier experiments.

  16. Report of the Committee on Antitrust

    SciTech Connect (OSTI)

    Not Available

    1987-01-01

    The report covers antitrust cases involving fourteen natural gas and four oil companies and two electric utilities. There is a brief summary describing each suit and the court decision if one has been reached. Among the issues were whether a gas company can wholly own a pipeline subsidiary, pipeline power to refuse transport, mergers and acquisitions by stockholders, termination of service, oil futures, alleged price-fixing, and wholesale electric contracts.

  17. Chiral Two-body Currents and Neutrinoless Double Beta Decay

    SciTech Connect (OSTI)

    Menendez, Javier [Institut fuer Kernphysik, Technische Universitaet Darmstadt, 64289 Darmstadt (Germany); ExtreMe Matter Institute EMMI, GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany)

    2011-12-16

    The nuclear matrix elements (NMEs) of neutrinoless double-beta (0{nu}{beta}{beta}) decay are studied using weak currents derived in the framework of chiral effective field theory. Apart from the standard one-body (1b) currents, it is shown that two-body (2b) currents contribute to weak processes. The normal-ordered 1b part of 2b currents modifies the Gamow-Teller (GT){sigma}{tau}{sup -} part of the 1b current, contributing to the well-known quenching of GT single-{beta} decays. The momentum-transfer dependence of the quenching due to 2b currents is also predicted. Therefore, including 2b currents allows to address, microscopically, the problem of the axial weak coupling (g{sub A}) value, which is the biggest uncertainty in the 0{nu}{beta}{beta} decay NME calculations for all available methods.

  18. Preparation of reactive beta-dicalcium silicate

    DOE Patents [OSTI]

    Shen, Ming-Shing (Laramie, WY, NJ); Chen, James M. (Rahway, NJ); Yang, Ralph T. (Amherst, NY)

    1982-01-01

    This invention relates to the preparation of fine particles of reactive beta-dicalcium silicate by means of a solid state process which comprises firing a mixture of calcium sulfate, silica and a reducing additive selected from the group consisting of calcium sulfide, carbon, carbon monoxide, methane and hydrogen, at a temperature of about 850.degree.-1000.degree. C. A carrier gas such as nitrogen or carbon dioxide may also be added, if desired. A high concentration of sulfur dioxide is a by-product of this process.

  19. Preparation of reactive beta-dicalcium silicate

    DOE Patents [OSTI]

    Shen, M.S.; Chen, J.M.; Yang, R.T.

    1980-02-28

    This invention relates to the preparation of fine particles of reactive beta-dicalcium silicate by means of a solid state process which comprises firing a mixture of calcium sulfate, silica, and a reducing additive selected from the group consisting of calcium sulfide, carbon, carbon monoxide, methane, and hydrogen, at a temperature of about 850 to 1000/sup 0/C. A carrier gas such as nitrogen or carbon dioxide may also be added, if desired. A high concentration of sulfur dioxide is a by-product of this process.

  20. The BetaCage, an ultra-sensitive screener for surface contamination

    SciTech Connect (OSTI)

    Bunker, R.; Bowles, M. A.; Schnee, R. W.; Wang, B. [Department of Physics, Syracuse University, Syracuse, NY 13244 (United States)] [Department of Physics, Syracuse University, Syracuse, NY 13244 (United States); Ahmed, Z.; Golwala, S. R.; Nelson, R. H.; Rider, A.; Zahn, A. [California Institute of Technology, Pasadena, CA 91125 (United States)] [California Institute of Technology, Pasadena, CA 91125 (United States); Grant, D. R. [University of Alberta, Edmonton, AB, T6G 2R3 (Canada)] [University of Alberta, Edmonton, AB, T6G 2R3 (Canada); Kos, M. [Department of Physics, Syracuse University, Syracuse, NY 13244, USA and Pacific Northwest National Laboratory, Richland, WA 99352 (United States)] [Department of Physics, Syracuse University, Syracuse, NY 13244, USA and Pacific Northwest National Laboratory, Richland, WA 99352 (United States)

    2013-08-08

    Material screening for identifying low-energy electron emitters and alpha-decaying isotopes is now a prerequisite for rare-event searches (e.g., dark-matter direct detection and neutrinoless double-beta decay) for which surface radiocon-tamination has become an increasingly important background. The BetaCage, a gaseous neon time-projection chamber, is a proposed ultra-sensitive (and nondestructive) screener for alpha-and beta-emitting surface contaminants to which existing screening facilities are insufficiently sensitive. Sensitivity goals are 0.1 betas keV{sup ?1} m{sup ?2} day{sup ?1} and 0.1 alphas m{sup ?2} day{sup ?1}, with the former limited by Compton scattering of photons in the screening samples and (thanks to tracking) the latter expected to be signal-limited; radioassays and simulations indicate backgrounds from detector materials and radon daughters should be subdominant. We report on details of the background simulations and detector design that provide the discrimination, shielding, and radiopurity necessary to reach our sensitivity goals for a chamber with a 95 95 cm{sup 2} sample area positioned below a 40 cm drift region and monitored by crisscrossed anode and cathode planes consisting of 151 wires each.

  1. Human interleukin 2 receptor. beta. -chain gene: Chromosomal localization and identification of 5 prime regulatory sequences

    SciTech Connect (OSTI)

    Gnarra, J.R.; Otani, Hiroki; Wang, M.G.; McBride, O.W.; Sharon, M.; Leonard, W.J. )

    1990-05-01

    Interleukin 2 (IL-2) binds to and stimulates activated T cells through high-affinity IL-2 receptors (IL-2Rs). Such receptors represent a complex consisting of at least two proteins, the 55-kDa IL-2R{alpha} chain and the 70-kDa IL-2R{beta} chain. The low-affinity, IL-2R{alpha} chain cannot by itself transduce a mitogenic signal, whereas IL-2 stimulates resting lymphocytes through the intermediate-affinity, IL-2R{beta} receptor. The authors report here identification of the genomic locus for IL-2R{beta}. The exons are contained on four EcoRI fragments of 1.1, 9.2, 7.2, and 13.7 kilobases. The 1.1-kilobase EcoRI fragment lies at the 5{prime}-most end of the genomic locus and contains promoter sequences. The promoter contains no TATA box-like elements but does contain the d(GT){sub n} class of middle repetitive elements, which may play an interesting regulatory role. The IL-2R{beta} gene is localized to chromosome 22q11.2-q12, a region that is the locus for several lymphoid neoplasias.

  2. National Library of Energy (BETA): the Department of Energy's National

    Office of Scientific and Technical Information (OSTI)

    Resource for Energy Literacy, Innovation and Security - Communications Communications NLEBeta Announcement NLEBeta Articles & Blogs OSTI.gov Newsletter July/August 2014: National Library of EnergyBeta: Cool Search Tool for Summer Search Tip: National Library of EnergyBeta New Search OSTIblog, May 29, 2014: Refreshed National Library of EnergyBeta Takes on Expanded Role in Disseminating Department of Energy Scientific and Technical Information OSTIblog, September 26, 2013: The National

  3. Structure of a mutant [beta] toxin from Staphylococcus aureus reveals

    Office of Scientific and Technical Information (OSTI)

    domain swapping and conformational flexibility (Journal Article) | SciTech Connect Structure of a mutant [beta] toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility Citation Details In-Document Search Title: Structure of a mutant [beta] toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility The 3.35 {angstrom} resolution crystal structure of a mutant form of the staphylococcal sphingomyelinase {beta} toxin in which a

  4. Neutrinoless double beta decay search with the NEMO 3 experiment

    SciTech Connect (OSTI)

    Nasteva, Irina [Particle Physics Group, School of Physics and Astronomy, University of Manchester, Manchester, M13 9PL (United Kingdom)

    2008-11-23

    The NEMO 3 experiment searches for neutrinoless double beta decay and makes precision measurements of two-neutrino double beta decay in seven isotopes. The latest two-neutrino half-life results are presented, together with the limits on neutrinoless half-lives and the corresponding effective Majorana neutrino masses. Also given are the limits obtained on neutrinoless double beta decay mediated by R{sub p}-violating SUSY, right-hand currents and different Majoron emission modes.

  5. Proceedings of the Department of Energy workshop on beta measurements

    SciTech Connect (OSTI)

    Swinth, K.L.; Vallario, E.J.

    1987-09-01

    Participants discussed current practices, efforts to upgrade the quality of beta measurements, and initiatives necessary to improve the measurement and control of beta doses. This proceedings includes papers presented at the workshop, transcripts of panel and open discussions, and documentation of question and answer sessions. The information exchange resulting from this meeting is expected to provide a clearer focus on the problems of beta measurements.

  6. Labeled ALPHA4BETA2 ligands and methods therefor

    DOE Patents [OSTI]

    Mukherjee, Jogeshwar; Pichika, Ramaiah; Potkin, Steven; Leslie, Frances; Chattopadhyay, Sankha

    2013-02-19

    Contemplated compositions and methods are employed to bind in vitro and in vivo to an .alpha.4.beta.2 nicotinic acetylcholine receptor in a highly selective manner. Where such compounds are labeled, compositions and methods employing such compounds can be used for PET and SPECT analysis. Alternatively, and/or additionally contemplated compounds can be used as antagonists, partial agonists or agonists in the treatment of diseases or conditions associated with .alpha.4.beta..beta.2 dysfunction.

  7. Neutron Interactions in the CUORE Neutrinoless Double Beta Decay Experiment

    Office of Scientific and Technical Information (OSTI)

    (Thesis/Dissertation) | SciTech Connect Thesis/Dissertation: Neutron Interactions in the CUORE Neutrinoless Double Beta Decay Experiment Citation Details In-Document Search Title: Neutron Interactions in the CUORE Neutrinoless Double Beta Decay Experiment Neutrinoless double beta decay (0{nu}DBD) is a lepton-number violating process that can occur only for a massive Majorana neutrino. The search for 0{nu}DBD is currently the only practical experimental way to determine whether neutrinos are

  8. The Majorana Double Beta Decay Experiment: Present Status (Conference) |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Majorana Double Beta Decay Experiment: Present Status Citation Details In-Document Search Title: The Majorana Double Beta Decay Experiment: Present Status The Majorana collaboration is actively pursuing research and development aimed at a tonne-scale 76Ge neutrinoless double-beta decay experiment, an R&D effort that will field approximately 40 kg of germanium detectors with mixed enrichment levels. This article provides a status update on the construction of the

  9. Method for preparing Pb-.beta."-alumina ceramic

    DOE Patents [OSTI]

    Hellstrom, Eric E.

    1986-01-01

    A process is disclosed for preparing impermeable, polycrystalline samples of Pb-.beta."-alumina ceramic from Na-.beta."-alumina ceramic by ion exchange. The process comprises two steps. The first step is a high-temperature vapor phase exchange of Na by K, followed by substitution of Pb for K by immersing the sample in a molten Pb salt bath. The result is a polycrystalline Pb-.beta."-alumina ceramic that is substantially crack-free.

  10. In the OSTI Collections: Neutrinoless Double Beta Decay-Are Neutrinos and

    Office of Scientific and Technical Information (OSTI)

    Antineutrinos the Same? | OSTI, US Dept of Energy, Office of Scientific and Technical Information Neutrinoless Double Beta Decay-Are Neutrinos and Antineutrinos the Same? Dr. Watson computer sleuthing scientist. Article Acknowledgement: Dr. William N. Watson, Physicist DOE Office of Scientific and Technical Information Observational Obstacles Experiments References Reports available from SciTech Connect and E-print Network Organizations and Laboratories Additional Reference Figure 1. The

  11. Structure of a mutant [beta] toxin from Staphylococcus aureus...

    Office of Scientific and Technical Information (OSTI)

    Structure of a mutant beta toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility Citation Details In-Document Search Title: Structure of a ...

  12. Differential Impact of [beta] and [gamma] Residue Preorganization...

    Office of Scientific and Technical Information (OSTI)

    Differential Impact of beta and gamma Residue Preorganization on alphabetagamma-Peptide Helix Stability in Water Citation Details In-Document Search Title: Differential ...

  13. Low molecular weight thermostable .beta.-D-glucosidase from acidotherm...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Visual Patent Search Success Stories News Events Find More Like This Return to Search Low molecular weight thermostable .beta.-D-glucosidase from acidothermus cellulolyticus...

  14. What can we learn from neutrinoless double beta decay experiments...

    Office of Scientific and Technical Information (OSTI)

    What can we learn from neutrinoless double beta decay experiments? Citation Details ... Country of Publication: United States Language: English Subject: 72 nucleus, semileptonic ...

  15. Detection of alpha radiation in a beta radiation field

    DOE Patents [OSTI]

    Mohagheghi, Amir H.; Reese, Robert P.

    2001-01-01

    An apparatus and method for detecting alpha particles in the presence of high activities of beta particles utilizing an alpha spectrometer. The apparatus of the present invention utilizes a magnetic field applied around the sample in an alpha spectrometer to deflect the beta particles from the sample prior to reaching the detector, thus permitting detection of low concentrations of alpha particles. In the method of the invention, the strength of magnetic field required to adequately deflect the beta particles and permit alpha particle detection is given by an algorithm that controls the field strength as a function of sample beta energy and the distance of the sample to the detector.

  16. Neutron Interactions in the CUORE Neutrinoless Double Beta Decay...

    Office of Scientific and Technical Information (OSTI)

    Interactions in the CUORE Neutrinoless Double Beta Decay Experiment Dolinski, M J 72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; 73 NUCLEAR PHYSICS AND RADIATION PHYSICS;...

  17. SNL-EFDC V0.0 BETA

    Energy Science and Technology Software Center (OSTI)

    002401WKSTN00 SNL-EFDC (Environmental Fluid Dynamics Code) v. 0.0 beta http://sourceforge.net/projects/snl-efdc/

  18. Free boundary, high beta equilibrium in a large aspect ratio...

    Office of Scientific and Technical Information (OSTI)

    circular plasma boundary Citation Details In-Document Search Title: Free boundary, high beta equilibrium in a large aspect ratio tokamak with nearly circular plasma boundary An ...

  19. Neutron Beta Decay as a Probe of Weak Interactions (Conference...

    Office of Scientific and Technical Information (OSTI)

    Citation Details In-Document Search Title: Neutron Beta Decay as a Probe of Weak Interactions Authors: Saunders, Alexander 1 + Show Author Affiliations Los Alamos National ...

  20. Structure of the TGF-Beta Receptor Complex Reveals Evolutionary...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Structure of the TGF-Beta Receptor Complex Reveals Evolutionary Adaptations that have Led to Diversification of Function with the Superfamily Growth factors are peptides and ...

  1. What can we learn from neutrinoless double beta decay experiments...

    Office of Scientific and Technical Information (OSTI)

    experiments can answer four fundamental questions. 1) If neutrinoless double beta decay ... Journal Publication Date: 26 August 2004 Research Org: Ernest Orlando Lawrence Berkeley ...

  2. Low-temperature Sodium-Beta Battery - Energy Innovation Portal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Summary Rechargeable metallic sodium batteries have application in large-scale energy ... sodium-sulfur and sodium-nickel chloride, both referred to as sodium-beta batteries. ...

  3. Equilibrium pressure measurements in the beta region of palladium protide and palladium deuteride

    SciTech Connect (OSTI)

    Carstens, D.H.W.; David, W.R.

    1989-03-01

    We have measured the pressure-composition isotherms of the palladium-deuterium and palladium-protium systems in the beta region of both and the plateau region of the protide. For these two systems, data were measured at pressures up to about 3.5 MPa (500 psi) and at temperatures from 173 to 473 K. This study extends to a greater pressure and temperature regime the work on palladium hydrides reported previously by other authors. We also report results of an empirical analytical fit to the data for these two isotope systems. For completeness, we have applied our analysis to previously reported data for the tritide. The data were fit to an equation of the form P = exp/A + 2ln(R/(1 - R))-(B - CR)/T/ + exp(D + E/T), where R is the hydrogen-to-metal atomic ratio, P is the pressure, and T is the temperature. A, B, C, D, and E are empirically determined parameters and differ for absorbing and desorbing systems of each isotope. This equation gives a good fit to the data in the beta region of the absorption curves but a poorer fit in the alpha plus beta (plateau) region. 15 refs., 6 figs.

  4. The Promiscuity of [beta]-Strand Pairing Allows for Rational Design of [beta]-Sheet Face Inversion

    SciTech Connect (OSTI)

    Makabe, Koki; Koide, Shohei

    2009-06-17

    Recent studies suggest the dominant role of main-chain H-bond formation in specifying {beta}-sheet topology. Its essentially sequence-independent nature implies a large degree of freedom in designing {beta}-sheet-based nanomaterials. Here we show rational design of {beta}-sheet face inversions by incremental deletions of {beta}-strands from the single-layer {beta}-sheet of Borrelia outer surface protein A. We show that a {beta}-sheet structure can be maintained when a large number of native contacts are removed and that one can design large-scale conformational transitions of a {beta}-sheet such as face inversion by exploiting the promiscuity of strand-strand interactions. High-resolution X-ray crystal structures confirmed the success of the design and supported the importance of main-chain H-bonds in determining {beta}-sheet topology. This work suggests a simple but effective strategy for designing and controlling nanomaterials based on {beta}-rich peptide self-assemblies.

  5. Correlations and the neutrinoless double beta decay

    SciTech Connect (OSTI)

    Menendez, J.; Poves, A. [Departamento de Fisica Teorica, and IFT, UAM-CSIC, Universidad Autonoma de Madrid, 28049-Madrid (Spain); Caurier, E.; Nowacki, F. [IPHC, IN2P3-CNRS/Universite Louis Pasteur, 67037-Strasbourg (France)

    2009-11-09

    We explore the influence of the deformation on the nuclear matrix elements of the neutrinoless double beta decay (NME), concluding that the difference in deformation -or more generally on the amount of quadrupole correlations- between parent and grand daughter nuclei quenchs strongly the decay. We discuss how varies the nuclear matrix element of {sup 76}Ge decay when the wave functions of the two nuclei involved in the transition are constrained to reproduce the experimental occupancies. In the Interacting Shell Model description the value of the NME is enhanced about 15% compared to previous calculations, whereas in the QRPA the NME's are reduced by 20%-30%, thus, the discrepancies between both approaches diminish.

  6. Constraining mass spectra with sterile neutrinos from neutrinoless double beta decay, tritium beta decay, and cosmology

    SciTech Connect (OSTI)

    Goswami, Srubabati [Harish-Chandra Research Institute, Chhatnag Road, Jhunsi, Allahabad 211 019 (India); Physik-Department, Technische Universitaet Muenchen, James-Franck-Strasse, D-85748 Garching (Germany); Rodejohann, Werner [Physik-Department, Technische Universitaet Muenchen, James-Franck-Strasse, D-85748 Garching (Germany)

    2006-06-01

    We analyze the constraints on neutrino mass spectra with extra sterile neutrinos as implied by the LSND experiment. The various mass related observables in neutrinoless double beta decay, tritium beta decay and cosmology are discussed. Both neutrino oscillation results as well as recent cosmological neutrino mass bounds are taken into account. We find that some of the allowed mass patterns are severely restricted by the current constraints, in particular, by the cosmological constraints on the total sum of neutrino masses and by the nonmaximality of the solar neutrino mixing angle. Furthermore, we estimate the form of the four neutrino mass matrices and also comment on the situation in scenarios with two additional sterile neutrinos.

  7. Beta-endorphin and alpha-n-acetyl beta-endorphin; synthesis, conformation and binding parameter

    SciTech Connect (OSTI)

    Lovegren, E.S.

    1986-01-01

    Beta-endorphin (EP) is a 31-residue opioid peptide found in many tissues, including the pituitary, brain and reproductive tract. Alpha-amino-acetyl beta-endorphin (AcEP) was characterized spectroscopically by proton nuclear magnetic resonance (NMR) and circular dichroism in deuterated water and trifluoroethanol (TFE). Both EP and AcEP bind to neuroblastoma N2a cells. This binding was not mediated through opiate receptors, and both peptides seemed to bind at common sites. Ovarian immunoreactive-EP levels were determined for immature and mature rates. These levels were found to be responsive to exogenous gonadotropin treatment in immature animals. A large percentage of the immunoreactive-EP is present in follicular fluid, and most of the endorphin-like peptides were acetylated, as measured by radioimmunoassay. Chromatogaphic analysis suggested at least three EP-like species: EP, a carboxy-terminally cleaved and an amino-terminally acetylated EP.

  8. Mutant HNF-1{alpha} and mutant HNF-1{beta} identified in MODY3 and MODY5 downregulate DPP-IV gene expression in Caco-2 cells

    SciTech Connect (OSTI)

    Gu Ning [Laboratory of Metabolism, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto (Japan); Laboratory of Neurochemistry, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto (Japan); Adachi, Tetsuya [Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto (Japan); Matsunaga, Tetsuro [Laboratory of Metabolism, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto (Japan); Takeda, Jun [Department of Endocrinology Diabetes and Rheumatology, Graduate School of Medicine, Gifu University School of Medicine, Gifu (Japan); Tsujimoto, Gozoh [Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto (Japan); Ishihara, Akihiko [Laboratory of Neurochemistry, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto (Japan); Yasuda, Koichiro [Laboratory of Metabolism, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto (Japan); Diabetic Center, Tsunashimakai-Kosei Hospital, Himeji (Japan); Tsuda, Kinsuke [Laboratory of Metabolism, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto (Japan)]. E-mail: jinkan@tom.life.h.kyoto-u.ac.jp

    2006-08-04

    Dipeptidylpeptidase IV (DPP-IV) is a well-documented drug target for the treatment of type 2 diabetes. Hepatocyte nuclear factors (HNF)-1{alpha} and HNF-1{beta}, known as the causal genes of MODY3 and MODY5, respectively, have been reported to be involved in regulation of DPP-IV gene expression. But, it is not completely clear (i) that they play roles in regulation of DPP-IV gene expression, and (ii) whether DPP-IV gene activity is changed by mutant HNF-1{alpha} and mutant HNF-1{beta} in MODY3 and MODY5. To explore these questions, we investigated transactivation effects of wild HNF-1{alpha} and 13 mutant HNF-1{alpha}, as well as wild HNF-1{beta} and 2 mutant HNF-1{beta}, on DPP-IV promoter luciferase gene in Caco-2 cells by means of a transient experiment. Both wild HNF-1{alpha} and wild HNF-1{beta} significantly transactivated DPP-IV promoter, but mutant HNF-1{alpha} and mutant HNF-1{beta} exhibited low transactivation activity. Moreover, to study whether mutant HNF-1{alpha} and mutant HNF-1{beta} change endogenous DPP-IV enzyme activity, we produced four stable cell lines from Caco-2 cells, in which wild HNF-1{alpha} or wild HNF-1{beta}, or else respective dominant-negative mutant HNF-1{alpha}T539fsdelC or dominant-negative mutant HNF-1{beta}R177X, was stably expressed. We found that DPP-IV gene expression and enzyme activity were significantly increased in wild HNF-1{alpha} cells and wild HNF-1{beta} cells, whereas they decreased in HNF-1{alpha}T539fsdelC cells and HNF-1{beta}R177X cells, compared with DPP-IV gene expression and enzyme activity in Caco-2 cells. These results suggest that both wild HNF-1{alpha} and wild HNF-1{beta} have a stimulatory effect on DPP-IV gene expression, but that mutant HNF-1{alpha} and mutant HNF-1{beta} attenuate the stimulatory effect.

  9. ON THE MISALIGNMENT OF THE DIRECTLY IMAGED PLANET {beta} PICTORIS b WITH THE SYSTEM'S WARPED INNER DISK

    SciTech Connect (OSTI)

    Dawson, Rebekah I.; Murray-Clay, Ruth A.; Fabrycky, Daniel C.

    2011-12-10

    The vertical warp in the debris disk {beta} Pictoris-an inclined inner disk extending into a flat outer disk-has long been interpreted as the signpost of a planet on an inclined orbit. Direct images spanning 2004-2010 have revealed {beta} Pictoris b, a planet with a mass and orbital distance consistent with this picture. However, it was recently reported that the orbit of planet b is aligned with the flat outer disk, not the inclined inner disk, and thus lacks the inclination to warp the disk. We explore three scenarios for reconciling the apparent misalignment of the directly imaged planet {beta} Pictoris b with the warped inner disk of {beta} Pictoris: observational uncertainty, an additional planet, and damping of planet b's inclination. We find that, at the extremes of the uncertainties, the orbit of {beta} Pictoris b has the inclination necessary to produce the observed warp. We also find that if planet b were aligned with the flat outer disk, it would prevent another planet from creating a warp with the observed properties; therefore planet b itself must be responsible for the warp. Finally, planet b's inclination could have been damped by dynamical friction and still produce the observed disk morphology, but the feasibility of damping depends on disk properties and the presence of other planets. More precise observations of the orbit of planet b and the position angle of the outer disk will allow us to distinguish between the first and third scenarios.

  10. {beta} decay spectroscopy of {sup 192}Pt and the nature of 0{sup +} excitations

    SciTech Connect (OSTI)

    McCutchan, E. A.; Casten, R. F.; Werner, V.; Winkler, R.; Williams, E.; Cakirli, R. B.; Guerdal, G.; Liang, X.

    2008-07-15

    Excited states in {sup 192}Pt were populated in {beta}{sup +}/{epsilon} decay and studied through off-beam {gamma}-ray spectroscopy. New coincidence data give no support for several reported low-energy, low-spin states proposed in {beta} decay and lead to a substantially revised level scheme. The structure of {sup 192}Pt is discussed in terms of both single-space IBA-1 calculations and two-space IBA calculations with configuration mixing. Both models together suggest that it is the perhaps the 0{sub 4}{sup +} state that corresponds to an intruder excitation, resulting from the excitation of a pair of protons across the Z=82 closed shell.

  11. Affinity and selectivity of beta-adrenoceptor antagonists in vitro

    SciTech Connect (OSTI)

    Wellstein, A.; Palm, D.; Belz, G.G.

    1986-01-01

    The potency order of the catecholamines (-)-isoprenaline (Iso), (-)-noradrenaline (NA), and (-)-adrenaline (Adr) in competition for radiolabelled sites is used for their pharmacological classification. It is shown that the radioligand /sup 3/H-CGP 12177 exclusively labels beta 1-adrenoceptors in rat salivary gland membranes (Iso greater than NA greater than Adr), and beta 2-adrenoceptors in rat reticulocytes (Iso greater than Adr greater than or equal to NA). These models are then used to derive the subtype-selectivity of the classical beta-adrenoceptor antagonists (+/-)-propranolol (prop; twofold beta 2-selective) and (+/-)-atenolol (aten; 35-fold beta 1-selective), as well as of the newer antagonists (+/-)-betaxolol and (+/-)-bisoprolol (betax and biso; 35-fold and 75-fold beta 1-selective, respectively). The ligand with the highest selectivity is ICI 118,551 (ICI), with a 300-fold beta 2-subtype selectivity. For comparison with antagonistic effects in humans at given plasma concentrations, the equilibrium dissociation constants of the ligands are measured in the presence of native human plasma and yield values for the relative selectively labelled subtype in the mean (Ki-values in nmol/l): prop: 20, aten: 250, biso: 24, betax: 23, and ICI: 2.5.

  12. Complementarity of Neutrinoless Double Beta Decay and Cosmology

    SciTech Connect (OSTI)

    Dodelson, Scott; Lykken, Joseph

    2014-03-20

    Neutrinoless double beta decay experiments constrain one combination of neutrino parameters, while cosmic surveys constrain another. This complementarity opens up an exciting range of possibilities. If neutrinos are Majorana particles, and the neutrino masses follow an inverted hierarchy, then the upcoming sets of both experiments will detect signals. The combined constraints will pin down not only the neutrino masses but also constrain one of the Majorana phases. If the hierarchy is normal, then a beta decay detection with the upcoming generation of experiments is unlikely, but cosmic surveys could constrain the sum of the masses to be relatively heavy, thereby producing a lower bound for the neutrinoless double beta decay rate, and therefore an argument for a next generation beta decay experiment. In this case as well, a combination of the phases will be constrained.

  13. Topics: Determining the Beta Limit - MST - UW Plasma Physics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Determining the Beta Limit UW Madison Madison Symmetric Torus Topics: Determining the Beta Limit MST HomeGraduate Student InformationLinksTourControl and Auxiliary SystemsPhysics TopicsDeviceResearch MissionMST People mst logo CPLA Home Directory Publications Links Internal University of Wisconsin Physics Department Research funding includes support from: Department of Energy National Science Foundation One of the reasons improved confinement in MST can be described as "tokamak-like"

  14. Estrogen induced {beta}-1,4-galactosyltransferase 1 expression regulates

    Office of Scientific and Technical Information (OSTI)

    proliferation of human breast cancer MCF-7 cells (Journal Article) | SciTech Connect Estrogen induced {beta}-1,4-galactosyltransferase 1 expression regulates proliferation of human breast cancer MCF-7 cells Citation Details In-Document Search Title: Estrogen induced {beta}-1,4-galactosyltransferase 1 expression regulates proliferation of human breast cancer MCF-7 cells Highlights: Black-Right-Pointing-Pointer We examined the regulation and biological functions of B4GALT1 expression induced

  15. No-neutrino double beta decay: more than one neutrino

    SciTech Connect (OSTI)

    Rosen, S.P.

    1983-01-01

    Interference effects between light and heavy Majorana neutrinos in the amplitude for no-neutrino double beta decay are discussed. The effects include an upper bound on the heavy neutrino mass, and an A dependence for the effective mass extracted from double beta decay. Thus the search for the no-neutrino decay mode should be pursued in several nuclei, and particularly in Ca/sup 48/, where the effective mass may be quite large.

  16. Adrenaline-activated structure of [beta subscript 2]-adrenoceptor

    Office of Scientific and Technical Information (OSTI)

    stabilized by an engineered nanobody (Journal Article) | SciTech Connect Adrenaline-activated structure of [beta subscript 2]-adrenoceptor stabilized by an engineered nanobody Citation Details In-Document Search Title: Adrenaline-activated structure of [beta subscript 2]-adrenoceptor stabilized by an engineered nanobody Authors: Ring, Aaron M. ; Manglik, Aashish ; Kruse, Andrew C. ; Enos, Michael D. ; Weis, William I. ; Garcia, K. Christopher ; Kobilka , Brian K. [1] ; Stanford-MED) [2] +

  17. Effect of nuclear deformation on double beta decay

    SciTech Connect (OSTI)

    Rodin, Vadim [Institute fuer Theoretische Physik der Universitaet Tuebingen, D-72076 Tuebingen (Germany)

    2009-11-09

    The existing ways of accounting for deformation in recent calculations of neutrinoless double beta decay matrix elements are discussed. From an analysis of relevant experimental data it is argued that only {sup 150}Nd reveals convincing evidences of strong static deformation, which should eventually be taken into account in QRPA calculations. A proposal which allows in principle to measure the neutrino less double beta decay Fermi matrix element is briefly described.

  18. Properties of High Beta, Quasi-Axisymmetric NCSX Stellarator Configurations

    Office of Scientific and Technical Information (OSTI)

    (Conference) | SciTech Connect Conference: Properties of High Beta, Quasi-Axisymmetric NCSX Stellarator Configurations Citation Details In-Document Search Title: Properties of High Beta, Quasi-Axisymmetric NCSX Stellarator Configurations Quasi-axisymmetry, external kinks and ballooning stability are studied with respect to the plasma shaping and variation in the pressure and current profiles for NCSX. We show that while the kink stability may require a delicate boundary shaping, most

  19. Neutron Interactions in the CUORE Neutrinoless Double Beta Decay Experiment

    Office of Scientific and Technical Information (OSTI)

    (Thesis/Dissertation) | SciTech Connect Thesis/Dissertation: Neutron Interactions in the CUORE Neutrinoless Double Beta Decay Experiment Citation Details In-Document Search Title: Neutron Interactions in the CUORE Neutrinoless Double Beta Decay Experiment × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided as a public service. Visit OSTI to utilize

  20. RELAP-7 Beta Release: Summary of Capabilities

    SciTech Connect (OSTI)

    Martineau, Richard C.; Zhang, Hongbin; Zhao, Haihua

    2014-12-01

    RELAP-7 is a nuclear systems safety analysis code being developed at the Idaho National Laboratory (INL). Building upon the decades of software development at the INL, we began the development of RELAP-7 in 2011 to support the Risk Informed Safety Margins Characterization (RISMC) Pathway. As part of this development, the first lines of RELAP-7 code were committed to the software revision control repository on November 7th, 2011. The overall design goal of RELAP-7 is to take advantage of the previous thirty years of advancements in computer architecture, software design, numerical methods, and physical models in order to provide capabilities needed for the RISMC methodology and to support nuclear power safety analysis. RELAP-7 is built using the INL’s modern scientific software development framework, MOOSE (Multi-physics Object Oriented Simulation Environment). MOOSE provides improved numerical calculations (including higher-order integration in both space and time, yielding converged second-order accuracy). The RELAP-7 code structure is based on multiple physical component models such as pipes, junctions, pumps, etc. Each component can have options for different fluid models such as single- and two-phase flow. This component-based and physics-based software architecture allows RELAP-7 to adopt different physical models for different applications. A relatively new two-phase hydrodynamic model, termed the ''7-Equation model'' for two phasic pressures, velocities, energies, and volumetric fraction, is incorporated into RELAP-7 for liquid-gas (water-steam) flows. This new model allows second-order integration because it is well-posed, which will reduce the numerical error associated with traditional systems analysis codes. In this paper, we provide a RELAP-7 capability list describing analysis features, range of applicability, and reactor components that will be available for the December 15th, 2014 beta release of the software.

  1. What can we learn from neutrinoless double beta decay experiments? (Journal

    Office of Scientific and Technical Information (OSTI)

    Article) | SciTech Connect What can we learn from neutrinoless double beta decay experiments? Citation Details In-Document Search Title: What can we learn from neutrinoless double beta decay experiments? We assess how well next generation neutrinoless double beta decay and normal neutrino beta decay experiments can answer four fundamental questions. 1) If neutrinoless double beta decay searches do not detect a signal, and if the spectrum is known to be inverted hierarchy, can we conclude

  2. Short-baseline electron neutrino disappearance, tritium beta decay, and neutrinoless double-beta decay

    SciTech Connect (OSTI)

    Giunti, Carlo; Laveder, Marco [INFN, Sezione di Torino, Via P. Giuria 1, I-10125 Torino (Italy); Dipartimento di Fisica G. Galilei, Universita di Padova, and INFN, Sezione di Padova, Via F. Marzolo 8, I-35131 Padova (Italy)

    2010-09-01

    We consider the interpretation of the MiniBooNE low-energy anomaly and the gallium radioactive source experiments anomaly in terms of short-baseline electron neutrino disappearance in the framework of 3+1 four-neutrino mixing schemes. The separate fits of MiniBooNE and gallium data are highly compatible, with close best-fit values of the effective oscillation parameters {Delta}m{sup 2} and sin{sup 2}2{theta}. The combined fit gives {Delta}m{sup 2}(greater-or-similar sign)0.1 eV{sup 2} and 0.11(less-or-similar sign)sin{sup 2}2{theta}(less-or-similar sign)0.48 at 2{sigma}. We consider also the data of the Bugey and Chooz reactor antineutrino oscillation experiments and the limits on the effective electron antineutrino mass in {beta} decay obtained in the Mainz and Troitsk tritium experiments. The fit of the data of these experiments limits the value of sin{sup 2}2{theta} below 0.10 at 2{sigma}. Considering the tension between the neutrino MiniBooNE and gallium data and the antineutrino reactor and tritium data as a statistical fluctuation, we perform a combined fit which gives {Delta}m{sup 2}{approx_equal}2 eV and 0.01(less-or-similar sign)sin{sup 2}2{theta}(less-or-similar sign)0.13 at 2{sigma}. Assuming a hierarchy of masses m{sub 1}, m{sub 2}, m{sub 3}<beta} decay and neutrinoless double-{beta} decay are, respectively, between about 0.06 and 0.49 and between about 0.003 and 0.07 eV at 2{sigma}. We also consider the possibility of reconciling the tension between the neutrino MiniBooNE and gallium data and the antineutrino reactor and tritium data with different mixings in the neutrino and antineutrino sectors. We find a 2.6{sigma} indication of a mixing angle asymmetry.

  3. Energy Density Functional Study of Nuclear Matrix Elements for Neutrinoless {beta}{beta} Decay

    SciTech Connect (OSTI)

    Rodriguez, Tomas R. [GSI Helmholtzzentrum fuer Schwerionenforschung, D-64259 Darmstadt (Germany); Departamento de Fisica Teorica, Universidad Autonoma de Madrid, E-28049 Madrid (Spain); CEA, Irfu, SPhN, Centre de Saclay, F-911191 Gif-sur-Yvette (France); Martinez-Pinedo, Gabriel [GSI Helmholtzzentrum fuer Schwerionenforschung, D-64259 Darmstadt (Germany)

    2010-12-17

    We present an extensive study of nuclear matrix elements (NME) for the neutrinoless double-beta decay of the nuclei {sup 48}Ca, {sup 76}Ge, {sup 82}Se, {sup 96}Zr, {sup 100}Mo, {sup 116}Cd, {sup 124}Sn, {sup 128}Te, {sup 130}Te, {sup 136}Xe, and {sup 150}Nd based on state-of-the-art energy density functional methods using the Gogny D1S functional. Beyond-mean-field effects are included within the generating coordinate method with particle number and angular momentum projection for both initial and final ground states. We obtain a rather constant value for the NMEs around 4.7 with the exception of {sup 48}Ca and {sup 150}Nd, where smaller values are found. We analyze the role of deformation and pairing in the evaluation of the NME and present detailed results for the decay of {sup 150}Nd.

  4. Shell model analysis of the neutrinoless double-{beta} decay of {sup 48}Ca

    SciTech Connect (OSTI)

    Horoi, Mihai [Department of Physics, Central Michigan University, Mount Pleasant, Michigan 48859 (United States); Stoica, Sabin [Horia Hulubei National Institute for Physics and Nuclear Engineering (IFIN-HH), 407 Atomistilor, Magurele-Bucharest, R-077125 (Romania)

    2010-02-15

    The neutrinoless double-{beta} (0{nu}{beta}{beta}) decay process could provide crucial information to determine the absolute scale of neutrino masses, and it is the only one that can establish whether a neutrino is a Dirac or a Majorana particle. A key ingredient for extracting the absolute neutrino masses from 0{nu}{beta}{beta} decay experiments is a precise knowledge of the nuclear matrix elements (NMEs) describing the half-life of this process. We developed a shell model approach for computing the 0{nu}{beta}{beta} decay NME, and we used it to analyze the 0{nu}{beta}{beta} mode of {sup 48}Ca. The dependence of the NME on the short-range correlation parameters, on the average energy of the intermediate states, on the finite-size cutoff parameters, and on the effective interaction used for many-body calculations is discussed.

  5. Resizing the conformal window: A {beta}-function ansatz

    SciTech Connect (OSTI)

    Antipin, O.; Tuominen, K.

    2010-04-01

    We propose an ansatz for the nonperturbative beta-function of a generic nonsupersymmetric Yang-Mills theory with or without fermions in an arbitrary representation of the gauge group. While our construction is similar to the recently proposed Ryttov-Sannino all-order beta-function, the essential difference is that it allows for the existence of an unstable ultraviolet fixed point in addition to the predicted Banks-Zaks-like infrared stable fixed point. Our beta-function preserves all of the tested features with respect to the nonsupersymmetric Yang-Mills theories. We predict the conformal window identifying the lower end of it as a merger of the infrared and ultraviolet fixed points.

  6. Reduction of beta* and increase of luminosity at RHIC

    SciTech Connect (OSTI)

    Pilat,F.; Bai, M.; Bruno, D.; Cameron, P.; Della Penna, A.; Drees, A.; Litvinenko, V.; Luo, Y.; Malitsky, N.; Marr, G.; Ptitsyn, V.; Satogata, T.; Tepikian, S.; Trbojevic, D.

    2009-05-04

    The reduction of {beta}* beyond the 1m design value at RHIC has been consistently achieved over the last 6 years of RHIC operations, resulting in an increase of luminosity for different running modes and species. During the recent 2007-08 deuteron-gold run the reduction to 0.70 from the design 1m achieved a 30% increase in delivered luminosity. The key ingredients allowing the reduction have been the capability of efficiently developing ramps with tune and coupling feedback, orbit corrections on the ramp, and collimation, to minimize beam losses in the final focus triplets, the main aperture limitations for the collision optics. We will describe the operational strategy used to reduce the {beta}*, at first squeezing the beam at store, to test feasibility, followed by the operationally preferred option of squeezing the beam during acceleration, and the resulting luminosity increase. We will conclude with future plans for the beta squeeze.

  7. Extra dimensions and neutrinoless double beta decay experiments

    SciTech Connect (OSTI)

    Gozdz, Marek; Kaminski, Wieslaw A.; Faessler, Amand [Theoretical Physics Department, Maria Curie-Sklodowska University, Lublin (Poland); Institute fuer Theoretische Physik, Universitaet Tuebingen, Auf der Morgenstelle 14, D-72076 Tuebingen (Germany)

    2005-05-01

    The neutrinoless double beta decay is one of the few phenomena, belonging to the nonstandard physics, which is extensively being sought for in experiments. In the present paper the link between the half-life of the neutrinoless double beta decay and theories with large extra dimensions is explored. The use of the sensitivities of currently planned 0{nu}2{beta} experiments: DAMA, CANDLES, COBRA, DCBA, CAMEO, GENIUS, GEM, MAJORANA, MOON, CUORE, EXO, and XMASS, gives the possibility for a nondirect 'experimental' verification of various extra dimensional scenarios. We discuss also the results of the Heidelberg-Moscow Collaboration. The calculations are based on the Majorana neutrino mass generation mechanism in the Arkani-Hamed-Dimopoulos-Dvali model.

  8. Double-{beta} decay Q value of {sup 150}Nd

    SciTech Connect (OSTI)

    Kolhinen, V. S.; Eronen, T.; Gorelov, D.; Hakala, J.; Jokinen, A.; Kankainen, A.; Moore, I. D.; Rissanen, J.; Saastamoinen, A.; Suhonen, J.; Aeystoe, J. [Department of Physics, P. O. Box 35 (YFL), FI-40014 University of Jyvaeskylae (Finland)

    2010-08-15

    The double-{beta} decay Q value of {sup 150}Nd was determined by using the JYFLTRAP Penning trap mass spectrometer. The measured mass difference between {sup 150}Nd and {sup 150}Sm is 3371.38(20) keV. This new value deviates by 3.7 keV from the previously adopted value of 3367.7(22) keV and is a factor of 10 more precise. Accurate knowledge of this Q value is important because {sup 150}Nd is a primary candidate to be used in the search for neutrinoless double-{beta} decay modes in several experiments.

  9. Consistency test of neutrinoless double beta decay with one isotope

    SciTech Connect (OSTI)

    Duerr, Michael; Lindner, Manfred [Max-Planck-Institut fuer Kernphysik, Postfach 10 39 80, 69029 Heidelberg (Germany); Zuber, Kai [Technical University Dresden, Institut fuer Kern- und Teilchenphysik, 01069 Dresden (Germany)

    2011-11-01

    We discuss a consistency test which makes it possible to discriminate unknown nuclear background lines from neutrinoless double beta decay with only one isotope. By considering both the transition to the ground state and to the first excited 0{sup +} state, a sufficiently large detector can reveal if neutrinoless double beta decay or some other nuclear physics process is at work. Such a detector could therefore simultaneously provide a consistency test for a certain range of Majorana masses and be sensitive to lower values of the effective Majorana mass .

  10. Cold fusion: externally induced beta decay of the deuteron?

    SciTech Connect (OSTI)

    Driscoll, R.B.

    1995-04-01

    Plasma frequencies {nu}{sub e} of interstitial electrons in palladium crystals charged with deuterium by electrolysis can reach resonance with the beats of de Broglie group frequencies of deuterons. This frequency can occur during acoustic compressions of lattices due to (1) bubble formation at the Pd cathode, (2) particles from cosmic ray showers, and (3) beta decays of deuterons. Resonance perturbs the orbits of deuterons nucleon constituents with a finite probability of causing dissociation and beta decay -- that is the basic conjecture. The exponential tendency resulting from cause (3) of lattice compression is limited by melting of the lattice, whose integrity is essential for {nu}{sub e}, which drives the decays.

  11. IL1{beta}-mediated Stromal COX-2 signaling mediates proliferation and invasiveness of colonic epithelial cancer cells

    SciTech Connect (OSTI)

    Zhu, Yingting; Tissue Tech Inc, Miami, FL 33173 ; Zhu, Min; Lance, Peter

    2012-11-15

    COX-2 is a major inflammatory mediator implicated in colorectal inflammation and cancer. However, the exact origin and role of COX-2 on colorectal inflammation and carcinogenesis are still not well defined. Recently, we reported that COX-2 and iNOS signalings interact in colonic CCD18Co fibroblasts. In this article, we investigated whether activation of COX-2 signaling by IL1{beta} in primary colonic fibroblasts obtained from normal and cancer patients play a critical role in regulation of proliferation and invasiveness of human colonic epithelial cancer cells. Our results demonstrated that COX-2 level was significantly higher in cancer associated fibroblasts than that in normal fibroblasts with or without stimulation of IL-1{beta}, a powerful stimulator of COX-2. Using in vitro assays for estimating proliferative and invasive potential, we discovered that the proliferation and invasiveness of the epithelial cancer cells were much greater when the cells were co-cultured with cancer associated fibroblasts than with normal fibroblasts, with or without stimulation of IL1{beta}. Further analysis indicated that the major COX-2 product, prostaglandin E{sub 2}, directly enhanced proliferation and invasiveness of the epithelial cancer cells in the absence of fibroblasts. Moreover, a selective COX-2 inhibitor, NS-398, blocked the proliferative and invasive effect of both normal and cancer associate fibroblasts on the epithelial cancer cells, with or without stimulation of IL-1{beta}. Those results indicate that activation of COX-2 signaling in the fibroblasts plays a major role in promoting proliferation and invasiveness of the epithelial cancer cells. In this process, PKC is involved in the activation of COX-2 signaling induced by IL-1{beta} in the fibroblasts.

  12. GERDA, a GERmanium Detector Array for the search for neutrinoless {beta}{beta} decay in 76Ge

    SciTech Connect (OSTI)

    Pandola, L.; Tomei, C. [INFN, Laboratori Nazionali del Gran Sasso, S.S. 17 bis km 18.910, 67010 Assergi (AQ) (Italy)

    2006-07-11

    The GERDA project, searching for neutrinoless double beta-decay of 76Ge with enriched germanium detectors submerged in a cryogenic bath, has been approved for installation at the Gran Sasso National Laboratory (LNGS), Italy. The GERDA technique is aiming at a dramatic reduction of the background due to radioactive contaminations of the materials surrounding the detectors. This will lead to a sensitivity of about 1026 years on the half-life of neutrinoless double beta decay. Already in the first phase of the experiment, GERDA will be able to investigate with high statistical significance the claimed evidence for neutrinoless double beta decay of 76Ge based on the data of the Heidelberg-Moscow experiment.

  13. Method for preparing 6-.beta.-halopenicillanic acids

    DOE Patents [OSTI]

    Hansen, Erik I.; Kran-Nielsen, Mogens P.; Von Daehne, Welf

    1989-01-01

    The present invention relates to a new and improved method for the preparation of a compound of the formula I ##STR1## in which R stands for halogen, giving rise to high yields of substantially pure 6.beta.-halopenicillanic acids, obtained in one step.

  14. Alpha-beta coordination method for collective search

    DOE Patents [OSTI]

    Goldsmith, Steven Y.

    2002-01-01

    The present invention comprises a decentralized coordination strategy called alpha-beta coordination. The alpha-beta coordination strategy is a family of collective search methods that allow teams of communicating agents to implicitly coordinate their search activities through a division of labor based on self-selected roles and self-determined status. An agent can play one of two complementary roles. An agent in the alpha role is motivated to improve its status by exploring new regions of the search space. An agent in the beta role is also motivated to improve its status, but is conservative and tends to remain aggregated with other agents until alpha agents have clearly identified and communicated better regions of the search space. An agent can select its role dynamically based on its current status value relative to the status values of neighboring team members. Status can be determined by a function of the agent's sensor readings, and can generally be a measurement of source intensity at the agent's current location. An agent's decision cycle can comprise three sequential decision rules: (1) selection of a current role based on the evaluation of the current status data, (2) selection of a specific subset of the current data, and (3) determination of the next heading using the selected data. Variations of the decision rules produce different versions of alpha and beta behaviors that lead to different collective behavior properties.

  15. Beam position monitor sensitivity for low-[beta] beams

    SciTech Connect (OSTI)

    Shafer, R.E. )

    1994-10-10

    Design of a beam position monitor (BPM) which is sensitive to low velo charged particle beams is considered. Quantitative estimates are made for the corrections to the conventional approximations to solutions of the Laplace Equation in two-dimensions when a BPM is used to measure to position of low velocity (low-[beta]) beams. (AIP)

  16. Scaling factor inconsistencies in neutrinoless double beta decay

    SciTech Connect (OSTI)

    Cowell, S. [Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

    2006-02-15

    The modern theory of neutrinoless double beta decay includes a scaling factor that has often been treated inconsistently in the literature. The nuclear contribution to the decay half-life can be suppressed by 15%-20% when scaling factors are mismatched. Correspondingly, is overestimated.

  17. Majorana neutrino masses and the neutrinoless double-beta decay

    SciTech Connect (OSTI)

    Faessler, A. [University of Tuebingen, Institute of Theoretical Physics (Germany)], E-mail: amand.faessler@uni-tuebingen.de

    2006-12-15

    Neutrinoless double-beta decay is forbidden in the Standard Model of electroweak and strong interaction but allowed in most Grand Unified Theories (GUTs). Only if the neutrino is a Majorana particle (identical with its antiparticle) and if it has a mass is neutrinoless double-beta decay allowed. Apart from one claim that the neutrinoless double-beta decay in {sup 76}Ge is measured, one has only upper limits for this transition probability. But even the upper limits allow one to give upper limits for the electron Majorana neutrino mass and upper limits for parameters of GUTs and the minimal R-parity-violating supersymmetric model. One further can give lower limits for the vector boson mediating mainly the right-handed weak interaction and the heavy mainly right-handed Majorana neutrino in left-right symmetric GUTs. For that, one has to assume that the specific mechanism is the leading one for neutrinoless double-beta decay and one has to be able to calculate reliably the corresponding nuclear matrix elements. In the present work, one discusses the accuracy of the present status of calculating of the nuclear matrix elements and the corresponding limits of GUTs and supersymmetric parameters.

  18. Neutrinoless Double Beta Decay and {nu}-Mass Determination

    SciTech Connect (OSTI)

    Pedretti, M. [Universita dell Insubria, Via Vallegio 11, 22100 Como (Italy)

    2005-10-12

    The search for Neutrinoless Double Beta Decay could improve our knowledge on neutrino properties. After a brief discussion on the implications of the observation of this rare process, I will introduce the experimental approaches and review the prospects of the search for this nuclear transition.

  19. New Advances in Neutrinoless Double Beta Decay Matrix Elements

    SciTech Connect (OSTI)

    Munoz, Jose Barea [Instituto de Estructura de la Materia, C.S.I.C. Unidad Asociada al Departamento de Fisica Atomica, Molecular y Nuclear, Facultad de Fisica, Universidad de Sevilla, Apartado 1065, 41080 Sevilla (Spain)

    2010-08-04

    We present the matrix elements necessary to evaluate the half-life of some neutrinoless double beta decay candidates in the framework of the microscopic interacting boson model (IBM). We compare our results with those from other models and extract some simple features of the calculations.

  20. Neutrinoless double beta decay in the microscopic interacting boson model

    SciTech Connect (OSTI)

    Iachello, F. [Center for Theoretical Physics, Sloane Physics Laboratory Yale University New Haven, CT 06520-8120 (United States)

    2009-11-09

    The results of a calculation of the nuclear matrix elements for neutrinoless double beta decay in the closure approximation in several nuclei within the framework of the microscopic interacting boson model (IBM-2) are presented and compared with those calculated in the shell model (SM) and quasiparticle random phase approximation (QRPA)

  1. Conditions for detecting CP violation via neutrinoless double beta decay

    SciTech Connect (OSTI)

    Joniec, A.; Zralek, M. [Institute of Physics, University of Silesia, Uniwersytecka 4, 40-007 Katowice (Poland)

    2006-02-01

    Neutrinoless double beta decay data, together with information on the absolute neutrino masses obtained from the future KATRIN experiment and/or astrophysical measurements, provide a chance to find CP violation in the lepton sector with Majorana neutrinos. We derive and discuss necessary conditions which make discovery of such CP violation possible for the future neutrino oscillation and mass measurements data.

  2. Polypeptides having beta-glucosidase activity and polynucleotides encoding same

    DOE Patents [OSTI]

    Harris, Paul; Golightly, Elizabeth

    2012-11-27

    The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

  3. Polynucleotides encoding polypeptides having beta-glucosidase activity

    DOE Patents [OSTI]

    Harris, Paul; Golightly, Elizabeth

    2010-03-02

    The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

  4. Polypeptides having beta-glucosidase activity and polynucleotides encoding same

    DOE Patents [OSTI]

    Harris, Paul; Golightly, Elizabeth

    2011-06-14

    The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

  5. The Majorana Double Beta Decay Experiment: Present Status

    SciTech Connect (OSTI)

    Aguayo, Estanislao; Avignone, Frank T.; Back, Henning O.; Barabash, Alexander S.; Beene, Jim; Bergevin, M.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Chan, Yuen-Dat; Christofferson, C. D.; Collar, J. I.; Combs, Dustin C.; Cooper, R. J.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Esterline, James H.; Fast, James E.; Fields, N.; Finnerty, P.; Fraenkle, Florian; Gehman, Victor M.; Giovanetti, G. K.; Green, M. P.; Guiseppe, V. E.; Gusey, K.; Hallin, A. L.; Hazama, R.; Henning, Reyco; Hime, Andrew; Hoppe, Eric W.; Horton, Mark; Howard, Stanley; Howe, M. A.; Johnson, R. A.; Keeter, K.; Keller, C.; Kidd, M. F.; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; Laferriere, Brian D.; LaRoque, B. H.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; MacMullin, S.; Marino, Michael G.; Martin, R. D.; Mei, Dong-Ming; Merriman, Jason H.; Miller, M. L.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; Overman, Nicole R.; Phillips II, D. G.; Poon, Alan; Perumpilly, Gopakumar; Prior, Gersende; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Schubert, Alexis G.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Steele, David; Strain, J.; Thomas, K.; Timkin, V.; Tornow, W.; Vanyushin, I.; Varner, R. L.; Vetter, Kai; Vorren, Kris R.; Wilkerson, J. F.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir; Zhang, C.

    2013-06-01

    The Majorana collaboration is actively pursuing research and development aimed at a tonne-scale 76Ge neutrinoless double-beta decay experiment, an R&D effort that will field approximately 40 kg of germanium detectors with mixed enrichment levels. This article provides a status update on the construction of the Demonstrator

  6. Preparation of {alpha}, {beta}-unsaturated carboxylic acids and anhydrides

    DOE Patents [OSTI]

    Spivey, J.J.; Gogate, M.R.; Zoeller, J.R.; Tustin, G.C.

    1998-01-20

    Disclosed is a process for the preparation of {alpha},{beta}-unsaturated carboxylic acids and anhydrides thereof which comprises contacting formaldehyde or a source of formaldehyde with a carboxylic anhydride in the presence of a catalyst comprising mixed oxides of vanadium, phosphorus and, optionally, a third component selected from titanium, aluminum or, preferably silicon.

  7. Preparation of .alpha.,.beta.-unsaturated carboxylic acids and esters

    DOE Patents [OSTI]

    Gogate, Makarand Ratnakar; Spivey, James Jerry; Zoeller, Joseph Robert

    1998-01-01

    Disclosed is a process for the preparation of .alpha.,.beta.-unsaturated carboxylic acids and esters thereof which comprises contacting formaldehyde or a source of formaldehyde with a carboxylic acid, ester or anhydride in the presence of a catalyst comprising an oxide of niobium.

  8. Preparation of .alpha., .beta.-unsaturated carboxylic acids and anhydrides

    DOE Patents [OSTI]

    Spivey, James Jerry; Gogate, Makarand Ratnakav; Zoeller, Joseph Robert; Tustin, Gerald Charles

    1998-01-01

    Disclosed is a process for the preparation of .alpha.,.beta.-unsaturated carboxylic acids and anhydrides thereof which comprises contacting formaldehyde or a source of formaldehyde with a carboxylic anhydride in the presence of a catalyst comprising mixed oxides of vanadium, phosphorus and, optionally, a third component selected from titanium, aluminum or, preferably silicon.

  9. Preparation of {alpha},{beta}-unsaturated carboxylic acids and esters

    DOE Patents [OSTI]

    Gogate, M.R.; Spivey, J.J.; Zoeller, J.R.

    1998-09-15

    Disclosed is a process for the preparation of {alpha},{beta}-unsaturated carboxylic acids and esters thereof which comprises contacting formaldehyde or a source of formaldehyde with a carboxylic acid, ester or anhydride in the presence of a catalyst comprising an oxide of niobium.

  10. Polypeptides having beta-glucosidase activity and polynucleotides encoding same

    SciTech Connect (OSTI)

    Harris, Paul; Golightly, Elizabeth

    2007-07-17

    The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

  11. Polypeptides having beta-glucosidase activity and polynucleotides encoding same

    DOE Patents [OSTI]

    Morant, Marc D; Patkar, Shamkant; Ding, Hanshu

    2013-11-12

    The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  12. Computer code for double beta decay QRPA based calculations

    SciTech Connect (OSTI)

    Barbero, C. A.; Mariano, A.; Krmpoti?, F.; Samana, A. R.; Ferreira, V. dos Santos; Bertulani, C. A.

    2014-11-11

    The computer code developed by our group some years ago for the evaluation of nuclear matrix elements, within the QRPA and PQRPA nuclear structure models, involved in neutrino-nucleus reactions, muon capture and ?{sup } processes, is extended to include also the nuclear double beta decay.

  13. Poster - DOE PAGES Beta | OSTI, US Dept of Energy, Office of Scientific and

    Office of Scientific and Technical Information (OSTI)

    Technical Information PAGES Beta Document Files and References Available Downloads for this Document: application/pdf icon Poster DOE PAGES Beta Last updated on Thursday 04 June

  14. Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting...

    Office of Scientific and Technical Information (OSTI)

    Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting Mode and Searching for Majoron-Emitting Modes Citation Details In-Document Search Title: Double Beta Decay in...

  15. Ultrafast Dynamic Response of Single Crystal PETN and Beta-HMX...

    Office of Scientific and Technical Information (OSTI)

    Conference: Ultrafast Dynamic Response of Single Crystal PETN and Beta-HMX Citation Details In-Document Search Title: Ultrafast Dynamic Response of Single Crystal PETN and Beta-HMX...

  16. Search for Neutrinoless Double-Beta Decay in 136Xe with EXO-200...

    Office of Scientific and Technical Information (OSTI)

    Neutrinoless Double-Beta Decay in 136Xe with EXO-200 Citation Details In-Document Search Title: Search for Neutrinoless Double-Beta Decay in 136Xe with EXO-200 Authors: Auger, M. ;...

  17. xLPR v2.0 beta 1 version status. (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    beta 1 version status. Citation Details In-Document Search Title: xLPR v2.0 beta 1 version status. Abstract not provided. Authors: Sallaberry, Cedric M. ; Dingreville, Remi ...

  18. BGL7 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2012-03-13

    The present invention provides BGL7 polypeptides with the biological activity of a .beta.-glucosidase and a method of producing a recombinant enzyme having .beta.-glucosidase activity.

  19. Beta.-glucosidase coding sequences and protein from orpinomyces PC-2

    DOE Patents [OSTI]

    Li, Xin-Liang; Ljungdahl, Lars G.; Chen, Huizhong; Ximenes, Eduardo A.

    2001-02-06

    Provided is a novel .beta.-glucosidase from Orpinomyces sp. PC2, nucleotide sequences encoding the mature protein and the precursor protein, and methods for recombinant production of this .beta.-glucosidase.

  20. Critical view to ''IGEX {sup 76}Ge neutrinoless double-beta decay experiment: Prospects for next generation experiments''

    SciTech Connect (OSTI)

    Klapdor-Kleingrothaus, H.V.; Dietz, A. [Max-Planck-Institut fuer Kernphysik, Postfach 10 39 80, D-69029 Heidelberg (Germany); Krivosheina, I. V. [Max-Planck-Institut fuer Kernphysik, Postfach 10 39 80, D-69029 Heidelberg (Germany); Radiophysical-Research Institute, Nishnii-Novgorod (Russian Federation)

    2004-10-01

    Recently, a paper entitled 'The IGEX {sup 76}Ge neutrinoless double-beta decay experiment: Prospects for next generation experiments' has been published [Phys. Rev. D 65, 092007 (2002)]. In view of the recently reported evidence for neutrinoless double-beta decay [Mod. Phys. Lett. A 16, 2409 (2001).; Found. Phys. 31, 1181 (2002); Phys. Lett. B 586, 198 (2004).], it is particularly unfortunate that the IGEX paper is rather incomplete in its presentation. We would like to point out in this Comment that and why it would be highly desirable to make more details about the experimental conditions and the analysis of IGEX available. We list some of the main points, which require further explanation. We also point to an arithmetic mistake in the analysis of the IGEX data, the consequence of which are too high half-life limits given in that paper.

  1. Fact Sheet: Sodium-Beta Batteries (October 2012) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Beta Batteries (October 2012) Fact Sheet: Sodium-Beta Batteries (October 2012) DOE's Energy Storage Program is funding research to further develop a novel planar design for sodium-beta batteries (Na-beta batteries or NBBs) that will improve energy and power densities and simplify manufacturing. This project will demonstrate a planar prototype that operates at <300 degrees Celsius and will scale up the storage capacity to 5 kW, improving on the performance levels being pursued in related

  2. The Search for Neutrinoless Double Beta Decay with 130Te with CUORE-0

    SciTech Connect (OSTI)

    Jonathan Loren Ouellet

    2015-06-02

    This thesis describes the design, operation and results of an experimental search for neutrinoless double beta decay (0$\

  3. TGF-.beta. antagonists as mitigators of radiation-induced tissue damage

    DOE Patents [OSTI]

    Barcellos-Hoff, Mary H.

    1997-01-01

    A method for treating tissue damage caused by radiation is described by use of a TGF-.beta. antagonist, such as an anti-TGF-.beta. antibody or a TGF-.beta. latency associated protein. It is administered not more than a week after exposure, and is particularly useful in mitigating the side effects of breast cancer therapy.

  4. TGF-{beta} antagonists as mitigators of radiation-induced tissue damage

    DOE Patents [OSTI]

    Barcellos-Hoff, M.H.

    1997-04-01

    A method for treating tissue damage caused by radiation is described by use of a TGF-{beta} antagonist, such as an anti-TGF-{beta} antibody or a TGF-{beta} latency associated protein. It is administered not more than a week after exposure, and is particularly useful in mitigating the side effects of breast cancer therapy.

  5. Search for Neutrinoless Double-Beta Decay of Te130 with CUORE-0

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Alfonso, K.; Artusa, D. R.; Avignone, F. T.; Azzolini, O.; Balata, M.; Banks, T. I.; Bari, G.; Beeman, J. W.; Bellini, F.; Bersani, A.; et al

    2015-09-03

    We report the results of a search for neutrinoless double-beta decay in a 9.8 kg yr exposure of 130Te using a bolometric detector array, CUORE-0. The characteristic detector energy resolution and background level in the region of interest are 5:1± 0:3 keV FWHM and 0:058 ± 0:004 (stat) ± 0:002 (syst) counts / (keV kg yr), respectively. The median 90% C.L. lower-limit half-life sensitivity of the experiment is 2:9x1024 yr and surpasses the sensitivity of previous searches. We find no evidence for neutrinoless double-beta decay of 130Te and place a Bayesian lower bound on the decay half-life, T0ν1/2 > 2.7more » x 1024 yr at 90% C.L. Combining CUORE-0 data with the 19.75 kg yr exposure of 130Te from the Cuoricino experiment we obtain T0ν1/2 > 4.0 x 1024 yr at 90% C.L. (Bayesian), the most stringent limit to date on this half-life. Lastly, using a range of nuclear matrix element estimates we interpret this as a limit on the e ective Majorana neutrino mass, mββ < 270 -760 meV.« less

  6. Measurement of the CP-Violating Phase beta_s in B0s -> J/Psi Phi Decays with the CDF II Detector

    SciTech Connect (OSTI)

    Aaltonen, T.; et al.

    2012-04-01

    We present a measurement of the \\CP-violating parameter \\betas using approximately 6500 $\\BsJpsiPhi$ decays reconstructed with the CDF\\,II detector in a sample of $p\\bar p$ collisions at $\\sqrt{s}=1.96$ TeV corresponding to 5.2 fb$^{-1}$ integrated luminosity produced by the Tevatron Collider at Fermilab. We find the \\CP-violating phase to be within the range $\\betas \\in [0.02, 0.52] \\cup [1.08, 1.55]$ at 68% confidence level where the coverage property of the quoted interval is guaranteed using a frequentist statistical analysis. This result is in agreement with the standard model expectation at the level of about one Gaussian standard deviation. We consider the inclusion of a potential $S$-wave contribution to the $\\Bs\\to J/\\psi K^+K^-$ final state which is found to be negligible over the mass interval $1.009 < m(K^+K^-)<1.028 \\gevcc$. Assuming the standard model prediction for the \\CP-violating phase \\betas, we find the \\Bs decay width difference to be $\\deltaG = 0.075 \\pm 0.035\\,\\textrm{(stat)} \\pm 0.006\\,\\textrm{(syst)} \\ps$. We also present the most precise measurements of the \\Bs mean lifetime $\\tau(\\Bs) = 1.529 \\pm 0.025\\,\\textrm{(stat)} \\pm 0.012\\,\\textrm{(syst)}$ ps, the polarization fractions $|A_0(0)|^2 = 0.524 \\pm 0.013\\,\\textrm{(stat)} \\pm 0.015\\,\\textrm{(syst)}$ and $|A_{\\parallel}(0)|^2 = 0.231 \\pm 0.014\\,\\textrm{(stat)} \\pm 0.015\\,\\textrm{(syst)}$, as well as the strong phase $\\delta_{\\perp}= 2.95 \\pm 0.64\\,\\textrm{(stat)} \\pm 0.07\\,\\textrm{(syst)} \\textrm{rad}$. In addition, we report an alternative Bayesian analysis that gives results consistent with the frequentist approach.

  7. Protonation of acyllithium reagents by acetonitrile: Synthesis of {beta}-hydroxy nitriles

    SciTech Connect (OSTI)

    Li, Nan-Sheng; Yu, Su; Kabalka, G.W. [Univ. of Tennessee, Knoxville, TN (United States)

    1995-09-08

    In recent years, the reaction of electrophiles with acyllithium (RCOLi) reagents has been extensively studied and has proven to be a convenient route to acylated products. For example, Seyferth reported that acyllithium reagents, generated in situ from an alkyllithium and carbon monoxide at -110 {degrees}C to -135 {degrees}C, would react with aldehydes, ketones, esters, lactones, isocyanates, isothiocyanates, carbodiimides, carbon disulfide, carbonyl sulfide, organic disulfides, iron pentacarbonyl, and trimethylchlorosilane to give acylated products. Nudelman found that the acyllithium generated from phenyllithium in the presence of alkyl bromides gave diphenylalkylcarbinols. The authors recently reported that trialkylboranes reacted with acyllithium reagents to afford ketones in modest yields. Although Seyferth predicted that acyl anion reagents might react with nitriles to afford addition products such as {alpha}-diketones, no report of a reaction of acyl anion reagents with nitriles has appeared in literature. Recently, the authors reported the first example of the protonation of acyllithium reagents by dichloromethane and dichloroarylmethane. The reaction affords the corresponding {alpha}, {alpha}-dichloro alcohols in excellent yields. The authors wish to report a new synthesis of {beta}-hydroxy nitriles which is based on the reaction of acyllithium with acetonitrile, Scheme 1. 1 tab.

  8. Double beta decay, Majorana neutrinos, and neutrino mass

    SciTech Connect (OSTI)

    Avignone, Frank T. III; Elliott, Steven R.; Engel, Jonathan [Department of Physics and Astronomy, University of South Carolina, Columbia, South Carolina 29208 (United States); Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Department of Physics and Astronomy, University of North Carolina, Chapel Hill, North Carolina 27599-3255 (United States)

    2008-04-15

    The theoretical and experimental issues relevant to neutrinoless double beta decay are reviewed. The impact that a direct observation of this exotic process would have on elementary particle physics, nuclear physics, astrophysics, and cosmology is profound. Now that neutrinos are known to have mass and experiments are becoming more sensitive, even the nonobservation of neutrinoless double beta decay will be useful. If the process is actually observed, we will immediately learn much about the neutrino. The status and discovery potential of proposed experiments are reviewed in this context, with significant emphasis on proposals favored by recent panel reviews. The importance of and challenges in the calculation of nuclear matrix elements that govern the decay are considered in detail. The increasing sensitivity of experiments and improvements in nuclear theory make the future exciting for this field at the interface of nuclear and particle physics.

  9. Neutrinoless double {beta}-decay and neutrino mass hierarchies

    SciTech Connect (OSTI)

    Bilenky, S. M. [Scuola Internazionale Superiore di Studi Avanzati, I-34014 Trieste (Italy); Faessler, Amand; Gutsche, Thomas; Simkovic, Fedor [Institute fuer Theoretische Physik der Universitaet Tuebingen, D-72076 Tuebingen (Germany)

    2005-09-01

    In the framework of the seesaw mechanism the normal hierarchy is favorable for the neutrino mass spectrum. For this spectrum we present a detailed calculation of the half-lives of neutrinoless double {beta}-decay for several nuclei of experimental interest. The half-lives are evaluated by considering the most comprehensive nuclear matrix elements, which were obtained within the renormalized quasiparticle random phase approximation by the Bratislava-Caltech-Tuebingen group. The dependence of the half-lives on sin{sup 2}{theta}{sub 13} and the lightest neutrino mass is studied. We present also the results of the calculations of the half-lives of neutrinoless double {beta}-decay in the case of the inverted hierarchy of neutrino masses.

  10. Results of the double beta decay experiment NEMO-3

    SciTech Connect (OSTI)

    Tretyak, V. I. [Joint Institute for Nuclear Research, 6 Joliot Curie, Dubna (Russian Federation); Collaboration: NEMO-3 Collaboration

    2013-12-30

    The double beta decay experiment NEMO-3 has taken data from February 2003 to January 2011. The two-neutrino decay half lives were measured for seven different isotopes ({sup 100}Mo, {sup 82}Se, {sup 116}Cd, {sup 150}Nd, {sup 96}Zr, {sup 48}Ca and {sup 130}Te). No evidence for neutrinoless double beta decay is observed. The 0??? half-life limits are found to be T{sub 1/2}{sup 0?}({sup 100}Mo)>1.010{sup 24}yr(90%C.L.) and T{sub 1/2}{sup 0?}({sup 82}Se)>3.210{sup 23}yr(90%C.L.)

  11. Modular low aspect ratio-high beta torsatron

    DOE Patents [OSTI]

    Sheffield, George V.; Furth, Harold P.

    1984-02-07

    A fusion reactor device in which the toroidal magnetic field and at least a portion of the poloidal magnetic field are provided by a single set of modular coils. The coils are arranged on the surface of a low aspect ratio toroid in planes having the cylindrical coordinate relationship .phi.=.phi..sub.i +kz where k is a constant equal to each coil's pitch and .phi..sub.i is the toroidal angle at which the i'th coil intersects the z=o plane. The device may be described as a modular, high beta torsation whose screw symmetry is pointed along the systems major (z) axis. The toroid defined by the modular coils preferably has a racetrack minor cross section. When vertical field coils and preferably a toroidal plasma current are provided for magnetic field surface closure within the toroid, a vacuum magnetic field of racetrack shaped minor cross section with improved stability and beta valves is obtained.

  12. High beta plasma operation in a toroidal plasma producing device

    DOE Patents [OSTI]

    Clarke, John F.

    1978-01-01

    A high beta plasma is produced in a plasma producing device of toroidal configuration by ohmic heating and auxiliary heating. The plasma pressure is continuously monitored and used in a control system to program the current in the poloidal field windings. Throughout the heating process, magnetic flux is conserved inside the plasma and the distortion of the flux surfaces drives a current in the plasma. As a consequence, the total current increases and the poloidal field windings are driven with an equal and opposing increasing current. The spatial distribution of the current in the poloidal field windings is determined by the plasma pressure. Plasma equilibrium is maintained thereby, and high temperature, high beta operation results.

  13. First Results of the Search for Neutrinoless Double-Beta Decay with the NEMO 3 Detector

    SciTech Connect (OSTI)

    Arnold, R.; Caurier, E.; Guyonnet, J.L.; Jollet, C.; Nowacki, F. [IReS, IN2P3-CNRS and ULP, 67037 Strasbourg (France); Augier, C.; Errahmane, K.; Etienvre, A.I.; Jullian, S.; Lalanne, D.; Sarazin, X.; Simard, L.; Szklarz, G. [LAL, IN2P3-CNRS and UPS, 91405 Orsay (France); Baker, J.; Caffrey, A.J. [INL, Idaho Falls, Idaho 83415 (United States); Barabash, A.; Konovalov, S.; Umatov, V.; Vanushin, I.; Vasilyev, V. [ITEP, 117259 Moscow (Russian Federation)] [and others

    2005-10-28

    The NEMO 3 detector, which has been operating in the Frejus underground laboratory since February 2003, is devoted to the search for neutrinoless double-beta decay ({beta}{beta}0{nu}). The half-lives of the two neutrino double-beta decay ({beta}{beta}2{nu}) have been measured for {sup 100}Mo and {sup 82}Se. After 389 effective days of data collection from February 2003 until September 2004 (phase I), no evidence for neutrinoless double-beta decay was found from {approx}7 kg of {sup 100}Mo and {approx}1 kg of {sup 82}Se. The corresponding limits are T{sub 1/2}({beta}{beta}0{nu})>4.6x10{sup 23} yr for {sup 100}Mo and T{sub 1/2}({beta}{beta}0{nu})>1.0x10{sup 23} yr for {sup 82}Se (90% C.L.). Depending on the nuclear matrix element calculation, the limits for the effective Majorana neutrino mass are <0.7-2.8 eV for {sup 100}Mo and <1.7-4.9 eV for {sup 82}Se.

  14. National Library of Energy (BETA): the Department of Energy's National

    Office of Scientific and Technical Information (OSTI)

    Resource for Energy Literacy, Innovation and Security - About NLE About The Department of Energy (DOE) National Library of EnergyBeta (NLEBeta) is a national resource to advance energy literacy, innovation and security. The NLEBeta is a new search tool designed to make it easier for American citizens to find and access information from across the DOE complex nationwide, without knowing DOE's organizational structure. Such information is offered by DOE to advance its four broad mission areas:

  15. National Library of Energy (Beta): the Department of Energy's National

    Office of Scientific and Technical Information (OSTI)

    Resource for Energy Literacy, Innovation and Security - FAQ Frequently Asked Questions What is the National Library of EnergyBeta (NLEBeta)? Why was the NLEBeta created? What does the NLEBeta search? What DOE program offices and national laboratories are included in the NLEBeta? Does the NLEBeta include any classified information? Does the NLEBeta host, edit, or revise any of the content on the NLEBeta? How is the NLEBeta search related to the DOE Energy.gov search? How often will the

  16. Weakly Turbulent Magnetohydrodynamic Waves in Compressible Low-{beta} Plasmas

    SciTech Connect (OSTI)

    Chandran, Benjamin D. G.

    2008-12-05

    In this Letter, weak-turbulence theory is used to investigate interactions among Alfven waves and fast and slow magnetosonic waves in collisionless low-{beta} plasmas. The wave kinetic equations are derived from the equations of magnetohydrodynamics, and extra terms are then added to model collisionless damping. These equations are used to provide a quantitative description of a variety of nonlinear processes, including parallel and perpendicular energy cascade, energy transfer between wave types, 'phase mixing', and the generation of backscattered Alfven waves.

  17. Challenges for a reliable shell model description of the neutrinoless double beta decay matrix elements

    SciTech Connect (OSTI)

    Horoi, Mihai [Department of Physics, Central Michigan University, Mount Pleasant, Michigan, 48859 (United States)

    2011-12-16

    Assuming that the neutrinos are Majorana particles and the neutrinoless double beta (0{nu}{beta}{beta}) decay is observed, a reliable 0{nu}{beta}{beta} matrix element is necessary to decide the neutrino mass hierarchy and the minimum neutrino mass. Many nuclear structure techniques, including the shell model, are presently used to calculate these matrix elements. In the last few years one could see a slow convergence of these results, but not yet at a level of 20 several shell model effective interactions and varying other parameters, finding results in a range that spans about 20In this contribution we describe challenges for obtaining reliable shell model 0{nu}{beta}{beta} matrix elements, with emphasis to {sup 76}Ge and {sup 82}Se decays.

  18. Diversity of [beta]-globin mutations in Israeli ethnic groups reflects recent historic events

    SciTech Connect (OSTI)

    Filon, D.; Oron, V.; Krichevski, S.; Shaag, A.; Goldfarb, A.; Aker, M.; Rachmilewitz, E.A.; Rund, D.; Oppenheim, A. )

    1994-05-01

    The authors characterized nearly 500 [beta]-thalassemia genes from the Israeli population representing a variety of ethnic subgroups. They found 28 different mutations in the [beta]-globin gene, including three mutations ([beta][sup S], [beta][sup C], and [beta][sup O-Arab]) causing hemoglobinopathies. Marked genetic heterogeneity was observed in both the Arab (20 mutations) and Jewish (17 mutations) populations. On the other hand, two ethnic isolates - Druze and Samaritans - had a single mutation each. Fifteen of the [beta]-thalassemia alleles are Mediterranean in type, 5 originated in Kurdistan, 2 are of Indian origin, and 2 sporadic alleles came from Europe. Only one mutant allele-nonsense codon 37-appears to be indigenous to Israel. While human habitation in Israel dates back to early prehistory, the present-day spectrum of [beta]-globin mutations can be largely explained by migration events that occurred in the past millennium. 26 refs., 2 figs., 3 tabs.

  19. Tribimaximal neutrino mixing and neutrinoless double beta decay

    SciTech Connect (OSTI)

    Hirsch, M.; Morisi, S.; Valle, J. W. F. [AHEP Group, Institut de Fisica Corpuscular-- C.S.I.C./Universitat de Valencia, Edificio Institutos de Paterna, Apt 22085, E-46071 Valencia (Spain)

    2008-11-01

    We present a tribimaximal lepton mixing scheme where the neutrinoless double beta decay rate has a lower bound which correlates with the ratio {alpha}{identical_to}{delta}m{sub sol}{sup 2}/{delta}m{sub atm}{sup 2} well determined by current data, as well as with the unknown Majorana CP phase {phi}{sub 12} characterizing the solar neutrino subsystem. For the special value {phi}{sub 12}=({pi}/2) (opposite CP-sign neutrinos) the {beta}{beta}{sub 0{nu}} rate vanishes at tree level when {delta}m{sub sol}{sup 2}/{delta}m{sub atm}{sup 2}=3/80, only allowed at 3{sigma}. For all other cases the rate is nonzero, and lies within current and projected experimental sensitivities close to {phi}{sub 12}=0. We suggest two model realizations of this scheme in terms of A{sub 4}xZ{sub 2} and A{sub 4}xZ{sub 4} flavor symmetries.

  20. Physics Division activities report, 1986--1987

    SciTech Connect (OSTI)

    Not Available

    1987-01-01

    This report summarizes the research activities of the Physics Division for the years 1986 and 1987. Areas of research discussed in this paper are: research on e/sup +/e/sup /minus// interactions; research on p/bar p/ interactions; experiment at TRIUMF; double beta decay; high energy astrophysics; interdisciplinary research; and advanced technology development and the SSC.

  1. Trash, ash and the phoenix : a fifth anniversary review of the Supreme Court's City of Chicago waste-to-energy combustion ash decision.

    SciTech Connect (OSTI)

    Puder, M. G.; Environmental Assessment

    1999-01-01

    In 1994, the U.S. Supreme Court held that ash generated by waste-to-energy (WTE) facilities was not exempt from Subtitle C hazardous waste management regulations under the Resource Conservation and Recovery Act (RCRA). As a result of City of Chicago v. Environmental Defense Fund, Inc., WTE installations are required to test their combustion ash and determine whether it is hazardous. The WTE industry and the municipalities utilizing WTE technologies initially feared that if significant amounts of their ash tested hazardous, the costs and liabilities associated with RCRA Subtitle C hazardous waste management requirements would pose a serious threat to the continued viability of the WTE concept. In this article, the author presents a review of the WTE industry in the five years following the decision, and finds that the specter of the decline of WTE has not materialized.

  2. Neutrinoless double {beta}-decay nuclear matrix elements within the SRQRPA with self-consistent short range correlations

    SciTech Connect (OSTI)

    Benes, Petr [IEAP, Czech Technical University (Czech Republic); Simkovic, Fedor [Department of Nuclear Physics and Biophysics, Comenius University, Mlynska dolina, SK-84248 Bratislava (Slovakia); Bogolyubov Laboratory of Theoretical Physics, JINR, Dubna (Russian Federation)

    2009-11-09

    The nuclear matrix elements M{sup 0v} of the neutrinoless double beta decay (0v{beta}{beta}-decay) are systematically evaluated using the self-consistent renormalized quasiparticle random phase approximation (SRQRPA). The residual interaction and the two-nucleon short-range correlations are derived from the charge-dependent Bonn (CD-Bonn) potential. The importance of further progress in the calculation of the 0v{beta}{beta}-decay nuclear matrix elements is stressed.

  3. Beam position monitor sensitivity for low-{beta} beams

    SciTech Connect (OSTI)

    Shafer, R.E.

    1993-11-01

    At low velocities, the EM field of a particle in a conducting beam tube is no longer a TEM wave, but has a finite longitudinal extent. The net effect of this is to reduce the coupling of the high-frequency Fourier components of the beam current to BPM (beam position monitor) electrodes, which modifies the BPM sensitivity to beam displacement. This effect is especially pronounced for high-frequency, large-aperture pickups used for low-{beta} beams. Non-interceptive beam position monitors used in conjunction with high frequency RFQ (radio-frequency-quadrupole) and DTL (drift-tube-linac) accelerators fall into this category. When testing a BPM with a thin wire excited with either pulses or high-frequency sinusoidal currents, the EM wave represents the principal (TEM) mode in a coaxial transmission line, which is equivalent to a highly relativistic ({beta} = 1) beam. Thus wire measurements are not suitable for simulating slow particle beams in high bandwidth diagnostic devices that couple to the image currents in the beam tube wall. Attempts to load the tin wire either capacitively or inductively to slow the EM wave down have met with limited success. In general, the equations used to represent the 2-D response of cylindrical-geometry BPMs to charged-particle beams make several assumptions: (1) the BPM electrodes are flush with and grounded to the surface of the conducting beam tube; (2) the beam is a line source (pencil beam); (3) the longitudinal extent of the EM field of a beam particle at the beam tube wall is zero, corresponding to a highly relativistic beam. The purpose of this paper is to make some quantitative estimates of the corrections to the conventional approximations when a BPM is used to measure the position of low velocity (low-{beta}) beams.

  4. Beta-decay measurements of neutron-deficient cesium isotopes

    SciTech Connect (OSTI)

    Parry, R.F.

    1983-03-01

    Beta decay endpoint energy measurements of the neutron deficient cesium isotopes were done using an energy spectrum shape fitting technique. This was a departure from the typical method of endpoint energy analysis, the Fermi-Kurie plot. A discussion of the shape fitting procedure and its improved features are discussed. These beta endpoint measurements have led to total decay energies (Q/sub EC/) of the neutron deficient /sup 119/ /sup 123/Cs isotopes. The total decay energies of /sup 122m/Cs (Q/sub EC/ = 6.95 +- 0.25 MeV) and /sup 119/Cs (Q/sub EC/ = 6.26 +- 0.29 MeV) were new measurements. The total decay energies of /sup 123/Cs (Q/sub EC/ = 4.05 +- 0.18 MeV), /sup 122g/Cs (Q/sub EC/ = 7.05 +- 0.18 MeV), /sup 121/Cs (Q/sub EC/ = 5.21 +- 0.22 MeV), and /sup 120/Cs (Q/sub EC/ = 7.38 +- 0.23 MeV) were measurements with significantly improved uncertainties as compared to the literature. Further, a combination of the energy levels derived from previous literature gamma-gamma coincident measurements and the experimental beta-coincident gamma decay energies has supported an improved level scheme for /sup 121/Xe and the proposal of three new energy levels in /sup 119/Xe. Comparison of the experimental cesium mass excesses (determined with our Q/sub EC/ values and known xenon mass excesses) with both the literature and theoretical predicted values showed general agreement except for /sup 120/Cs. Possible explanations for this deviation are discussed.

  5. Beta decay of 32Ar for fundamental tests

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Beta decay of 32 Ar for fundamental tests Chris Wrede University of Washington Argonne-ATLAS user meeting August 8 th , 2009 Outline * 1999 measurement of positron-neutrino correlation in 32 Ar(e + nu e ): ISOL facility (CERN-ISOLDE) * 2008 measurement the ft value for superallowed 32 Ar(e + nu e ) decay to test isospin symmetry breaking corrections: fragmentation facility (MSU-NSCL) * Where does ATLAS fit in to this? A bridge from stability to 32 Ar! Detecting scalar currents in weak decays n e

  6. Efficient double beta decay nuclear matrix elements computations

    SciTech Connect (OSTI)

    Neacsu, Andrei [Horia Hulubei Foundation (FHH) 407 Atomistilor, Horia Hulubei National Institute for Physics and Nuclear Engineering (IFIN-HH) 30 Reactorului, Magurele-Bucharest 077125 (Romania)

    2012-11-20

    We have developed a shell model code for the accurate computation of the two-body matrix elements of the transition operators involved in the neutrinoless double beta decay. This code features coupled cluster method short-range correlations with Jastrow-like functions, finite nucleon size effect and higher order nucleon current corrections. We present the results obtained for {sup 48}Ca and {sup 82}Se, then we compare them with other results in the literature. In the case of {sup 48}Ca, we also study the contributions of the included effects and find good agreement with other published results.

  7. beta. -Decay in the Skyrme-Witten representation of QCD

    SciTech Connect (OSTI)

    Snyderman, N.J.

    1991-05-01

    The renormalized coupling strength of the {beta}-decay axial vector current is related to {pi}{plus minus} p cross sections through the Adler-Weisberger sum rule, that follows from chiral symmetry. We attempt to understand the Adler-Weisberger sum rule in the 1/N{sub c} expansion in QCD, and in the Skyrme-Witten model that realizes the 1/N{sub c} expansion in the low energy limit, using it to explicitly calculate both g{sub A} and the {pi}{plus minus} p cross sections. 32 refs.

  8. Method for converting sucrose to .beta.-D-glucose

    DOE Patents [OSTI]

    Simmons, Blake A.; Volponi, Joanne V.; Ingersoll, David; Walker, Andrew

    2009-07-07

    Disclosed is an apparatus and method for continuously converting sucrose to .beta.-D-glucose. The method comprises a three-stage enzymatic reactor in which an aqueous solution of sucrose is first converted into a solution of fructose and .alpha.-D-glucose by passing it through a porous, packed column containing an inert media on which invertase is immobilized. This solution is then sent through a second packed column containing glucose isomerase and finally a third packed column containing mutarotase. Solution temperature and pH are adjusted to maximize glucose output.

  9. Unlike PPAR{gamma}, PPAR{alpha} or PPAR{beta}/{delta} activation does not promote human monocyte differentiation toward alternative macrophages

    SciTech Connect (OSTI)

    Bouhlel, Mohamed Amine; Inserm U545, F-59000 Lille; UDSL, F-59000 Lille; Institut Pasteur de Lille, F-59019 Lille ; Brozek, John; Derudas, Bruno; Inserm U545, F-59000 Lille; UDSL, F-59000 Lille; Institut Pasteur de Lille, F-59019 Lille ; Zawadzki, Christophe; Jude, Brigitte; Staels, Bart; Inserm U545, F-59000 Lille; UDSL, F-59000 Lille; Institut Pasteur de Lille, F-59019 Lille ; Chinetti-Gbaguidi, Giulia; Inserm U545, F-59000 Lille; UDSL, F-59000 Lille; Institut Pasteur de Lille, F-59019 Lille

    2009-08-28

    Macrophages adapt their response to micro-environmental signals. While Th1 cytokines promote pro-inflammatory M1 macrophages, Th2 cytokines promote an 'alternative' anti-inflammatory M2 macrophage phenotype. Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors expressed in macrophages where they control the inflammatory response. It has been shown that PPAR{gamma} promotes the differentiation of monocytes into anti-inflammatory M2 macrophages in humans and mice, while a role for PPAR{beta}/{delta} in this process has been reported only in mice and no data are available for PPAR{alpha}. Here, we show that in contrast to PPAR{gamma}, expression of PPAR{alpha} and PPAR{beta}/{delta} overall does not correlate with the expression of M2 markers in human atherosclerotic lesions, whereas a positive correlation with genes of lipid metabolism exists. Moreover, unlike PPAR{gamma}, PPAR{alpha} or PPAR{beta}/{delta} activation does not influence human monocyte differentiation into M2 macrophages in vitro. Thus, PPAR{alpha} and PPAR{beta}/{delta} do not appear to modulate the alternative differentiation of human macrophages.

  10. Double beta decay versus cosmology: Majorana CP phases and nuclear matrix elements

    SciTech Connect (OSTI)

    Deppisch, Frank; Paes, Heinrich [Institut fuer Theoretische Physik und Astrophysik, Universitaet Wuerzburg, D-97074 Wuerzburg (Germany); Suhonen, Jouni [Department of Physics, University of Jyvaeskylae, P.O.B. 35, FIN-40014, Jyvaeskylae (Finland)

    2005-08-01

    We discuss the relation between the absolute neutrino mass scale, the effective mass measured in neutrinoless double beta decay, and the Majorana CP phases. Emphasis is placed on estimating the upper bound on the nuclear matrix element entering calculations of the double beta decay half-life. Combining the claimed evidence for neutrinoless double beta decay with the neutrino mass bound from cosmology, one of the Majorana CP phases can be constrained.

  11. Shell model nuclear matrix elements for competing mechanisms contributing to double beta decay

    SciTech Connect (OSTI)

    Horoi, Mihai

    2013-12-30

    Recent progress in the shell model approach to the nuclear matrix elements for the double beta decay process are presented. This includes nuclear matrix elements for competing mechanisms to neutrionless double beta decay, a comparison between closure and non-closure approximation for {sup 48}Ca, and an updated shell model analysis of nuclear matrix elements for the double beta decay of {sup 136}Xe.

  12. The MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-beta Decay of

    Office of Scientific and Technical Information (OSTI)

    Germanium-76 (Conference) | SciTech Connect MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-beta Decay of Germanium-76 Citation Details In-Document Search Title: The MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-beta Decay of Germanium-76 The observation of neutrinoless double-beta decay would determine whether the neutrino is a Majorana particle and provide information on the absolute scale of neutrino mass. The MAJORANA Collaboration is constructing the DEMONSTRATOR, an

  13. THE MINERALOGY AND STRUCTURE OF THE INNER DEBRIS DISK OF {beta} PICTORIS

    SciTech Connect (OSTI)

    Li Dan; Telesco, Charles M.; Wright, Christopher M.

    2012-11-10

    We observed the edge-on, planet-bearing disk of {beta} Pictoris using T-ReCS at Gemini to clarify and extend previous observations and conclusions about this unique system. Our spectroscopy and spectral modeling of the 10 {mu}m silicate feature constrain the spatial distributions of three representative dust components (0.1 {mu}m/2.0 {mu}m glassy olivine and crystalline forsterite) across the inner 20 AU of the disk. We confirm that the 2.0 {mu}m glassy olivine is strongly peaked in the disk center and that the 0.1 {mu}m glassy olivine does not show this concentration, but rather is double peaked, with the peaks on either side of the star. However, we do not see the strong difference in brightness between those two peaks reported in a previous study. Although the spatial distribution of the 0.1 {mu}m dust is consistent with the scenario of a dust-replenishing planetesimal belt embedded in the disk, we note an alternative interpretation that can explain the spatial distributions of the 0.1 {mu}m and 2.0 {mu}m grains simultaneously and does not require the planetesimal belt. In addition to the spectroscopy, we also obtained a new 11.7 {mu}m image of the {beta} Pic disk. By comparing this image with that acquired in 2003, we confirm the existence and overall shape of the dusty clump at 52 AU in the SW disk. We speculate that the clump's projected spatial displacement of {approx}2.0 AU, a 3.6{sigma} result, between two epochs separated by seven years is due to the Keplerian motion of the clump at an orbital radius of 54.3{sup +2.0} {sub -1.2} AU.

  14. Effects of concomitant use of fibroblast growth factor (FGF)-2 with beta-tricalcium phosphate ({beta}-TCP) on the beagle dog 1-wall periodontal defect model

    SciTech Connect (OSTI)

    Anzai, Jun; Department of Periodontology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871 ; Kitamura, Masahiro; Nozaki, Takenori; Nagayasu, Toshie; Terashima, Akio; Asano, Taiji; Murakami, Shinya

    2010-12-17

    Research highlights: {yields} Concomitant use of FGF-2 and {beta}-TCP (an osteo-conductive scaffold) significantly promotes periodontal regeneration in the severe periodontitis model (1-wall defect model) of beagle dog. {yields} FGF-2 enhanced new bone formation via {beta}-TCP at the defects. {yields} In particular, FGF-2 dramatically regenerated new periodontal ligament and cementum formations at the defects, that is one of the most important healing outcomes during the process of periodontal regeneration. {yields} Epithelial downgrowth (undesirable wound healing) was decreased by administration of FGF-2. {yields} This manuscript indicates for the first time that concomitant use of FGF-2 and {beta}-TCP is efficacious in regenerating periodontal tissue following severe destruction of the tissue by progression of periodontitis. -- Abstract: The effects of concomitant use of fibroblast growth factor-2 (FGF-2) and beta-tricalcium phosphate ({beta}-TCP) on periodontal regeneration were investigated in the beagle dog 1-wall periodontal defect model. One-wall periodontal defects were created in the mesial portion of both sides of the mandibular first molars, and 0.3% FGF-2 plus {beta}-TCP or {beta}-TCP alone was administered. Radiographic evaluation was performed at 0, 3, and 6 weeks. At 6 weeks, the periodontium with the defect site was removed and histologically analyzed. Radiographic findings showed that co-administration of FGF-2 significantly increased bone mineral contents of the defect sites compared with {beta}-TCP alone. Histologic analysis revealed that the length of the regenerated periodontal ligament, the cementum, distance to the junctional epithelium, new bone height, and area of newly formed bone were significantly increased in the FGF-2 group. No abnormal inflammatory response or ankylosis was observed in either group. These findings indicate the efficacy of concomitant use of FGF-2 and {beta}-TCP as an osteoconductive material for periodontal regeneration following severe destruction by progressive periodontitis.

  15. Measurement of sin(2beta) in Tree-dominated B^0-Decays and Ambiguity Removal

    SciTech Connect (OSTI)

    Lacker, Heiko

    2007-03-05

    The most recent results from the B-factories on the time-dependent CP asymmetries measured in B{sup 0}-decays mediated by b {yields} c{bar c}s quark-transitions are reviewed. The Standard Model interpretation of the results in terms of the parameter sin 2{beta} leads to a four-fold ambiguity on the unitarity triangle {beta} which can be reduced to a two-fold ambiguity by measuring the sign of the parameter cos 2{beta}. The results on cos 2{beta} obtained so far are reviewed.

  16. Large Hadron Collider Probe of Supersymmetric Neutrinoless Double-Beta-Decay Mechanism

    SciTech Connect (OSTI)

    Allanach, B. C.; Kom, C. H.; Paes, H. [DAMTP, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WA (United Kingdom); Cavendish Laboratory, J. J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom); Fakultaet fuer Physik, Technische Universitaet Dortmund, D-44221, Dortmund (Germany)

    2009-08-28

    In the minimal supersymmetric extension to the standard model, a nonzero lepton number violating coupling {lambda}{sub 111}{sup '} predicts both neutrinoless double-beta-decay and resonant single slepton production at the LHC. We show that, in this case, if neutrinoless double beta decay is discovered in the next generation of experiments, there exist good prospects to observe single slepton production at the LHC. Neutrinoless double beta decay could otherwise result from a different source (such as a nonzero Majorana neutrino mass). Resonant single slepton production at the LHC can therefore discriminate between the {lambda}{sub 111}{sup '} neutrinoless double-beta-decay mechanism and others.

  17. Neutrinoless Double Beta Decay in Light of SNO Salt Data (Journal...

    Office of Scientific and Technical Information (OSTI)

    Dirac neutrinos if the invertedor degenerate mass spectrum will be confirmed by the improvements in cosmology, tritium data beta decay, or long-baseline oscillation experiments. ...

  18. Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting...

    Office of Scientific and Technical Information (OSTI)

    Title: Double Beta Decay in Xenon-136: Measuring the Neutrino-Emitting Mode and Searching for Majoron-Emitting Modes Authors: Herrin, Steven ; Stanford U., Phys. Dept. SLAC ...

  19. An EGF receptor inhibitor induces RAR-{beta} expression in breast and ovarian cancer cells

    SciTech Connect (OSTI)

    Grunt, Thomas W. . E-mail: thomas.grunt@meduniwien.ac.at; Puckmair, Klaudia; Tomek, Katharina; Kainz, Birgit; Gaiger, Alexander

    2005-04-22

    Inhibition of the epidermal growth factor (EGF)-receptor (EGFR) has become a promising anticancer treatment strategy. In addition, application of retinoids yields encouraging results for cancer prevention and therapy. Many tumors express no or low amounts of retinoic acid receptor-{beta}2 (RAR-{beta}2) due to epigenetic silencing via DNA hypermethylation. RAR-{beta}2 is the main mediator of the antiproliferative effect of retinoids. RAR-{beta}2 re-expression causes reversal of transformation, cell cycle arrest, and restoration of retinoid sensitivity. RAR-{beta}2 is thus a tumor suppressor. Western blotting, colorimetric in vitro cell proliferation assays, and reverse transcription-polymerase chain reaction demonstrated that the EGFR inhibitor PD153035 not only blocked activation of EGFR and inhibited cell growth, but also stimulated RAR-{beta} expression in MDA-MB-468 breast and OVCAR-3 ovarian carcinoma cells. Upregulation of RAR-{beta} by PD153035 was confirmed by real-time reverse transcription-polymerase chain reaction. In contrast, expression of other retinoid receptors and of estrogen receptor-{alpha} was not affected. PD153035-mediated re-induction of RAR-{beta} was associated with demethylation of the RAR-{beta}2 gene promoter P2 as demonstrated by methylation-specific polymerase chain reaction. These novel results on the ErbB/retinoid receptor cross-talk may be useful for designing future anticancer combination regimens.

  20. Neutrinoless Double Beta Decay in Light of SNO Salt Data (Journal...

    Office of Scientific and Technical Information (OSTI)

    In the SNO data from its salt run, probably the most significant result is the consistency ... Country of Publication: United States Language: English Subject: 72; BETA DECAY; ...

  1. Robust and Porous [beta]-Diketiminate-Functionalized Metal–Organic...

    Office of Scientific and Technical Information (OSTI)

    Robust and Porous beta-Diketiminate-Functionalized MetalOrganic Frameworks for Earth-A... MetalOrganic Frameworks for Earth-Abundant-Metal-Catalyzed CH Amination ...

  2. Building America Webinar: Release of BEopt 2.4 Beta | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Building America Webinar: Release of BEopt 2.4 Beta Building America Webinar: Release of BEopt 2.4 Beta July 13, 2015 1:00AM to 2:30PM EDT BEopt 2.4 Beta has recently been released, including multifamily capabilities! Please join us for a webinar on July 13 to view the latest BEopt features, provide feedback to the BEopt team, and see proposed features for the final release. The webinar will describe the new modeling features and interface capabilities provided in the latest BEopt 2.4 Beta.

  3. Neutrinoless double beta decay and future neutrino oscillation precision experiments

    SciTech Connect (OSTI)

    Choubey, Sandhya [Theoretical Physics, University of Oxford, 1 Keble Road, Oxford OX1 3NP (United Kingdom); Rodejohann, Werner [Physik-Department, Technische Universitaet Muenchen, James-Franck-Strasse, D-85748 Garching (Germany)

    2005-08-01

    We discuss to what extent future precision measurements of neutrino mixing observables will influence the information we can draw from a measurement of (or an improved limit on) neutrinoless double beta decay. Whereas the {delta}m{sup 2} corresponding to solar and atmospheric neutrino oscillations are expected to be known with good precision, the parameter {theta}{sub 12} will govern a large part of the uncertainty. We focus, in particular, on the possibility of distinguishing the neutrino mass hierarchies and on setting a limit on the neutrino mass. We give the largest allowed values of the neutrino masses which allow to distinguish the normal from the inverted hierarchy. All aspects are discussed as a function of the uncertainty stemming from the involved nuclear matrix elements. The implications of a vanishing, or extremely small, effective mass are also investigated. By giving a large list of possible neutrino mass matrices and their predictions for the observables, we finally explore how a measurement of (or an improved limit on) neutrinoless double beta decay can help to identify the neutrino mass matrix if more precise values of the relevant parameters are known.

  4. Compact Beta Particle/Positron Imager for Plant Biology

    SciTech Connect (OSTI)

    Weisenberger, Andrew; Lee, Seung Joon; McKisson, John; Xi, Wenze; Zorn, Carl; Stolin, Alexander; Majewski, Stan; Majewski, Stanislaw; Howell, Calvin; Crowell, Alec

    2011-06-01

    The 11CO2 tracer is used to facilitate plant biology research towards optimization of plant productivity, biofuel development and carbon sequestration in biomass. Positron emission tomography (PET) imaging has been used to study carbon transport in live plants using 11CO2. Plants typically have very thin leaves resulting in little medium for the emitted positrons to undergo an annihilation event. For the emitted positron from 11C decay approximately 1mm of water equivalent material is needed for positron annihilation. Thus most of the positrons do not annihilate inside the leaf, resulting in limited sensitivity for PET imaging. To address this problem we have developed a compact beta-positive beta-minus particle (BPBM) imager for 11CO2 leaf imaging. The detector is based on a Hamamatsu H8500 position sensitive photomultiplier tube optically coupled via optical grease and a 3mm thick glass plate to a 0.5mm thick Eljin EJ-212 plastic scintillator. The detector is equipped with a flexible arm to allow its placement and orientation on the leaf of the plant of interest while maintaining the leaf's original orientation. We are planning to utilize the imaging device at the Duke University Phytotron to investigate dynamic carbon transport differences between invasive and native species.

  5. Minimally allowed beta beata 0_nu rates from approximate flavor symmetries

    SciTech Connect (OSTI)

    Jenkins, James [Los Alamos National Laboratory

    2008-01-01

    Neutrinoless double beta decay ({beta}{beta}0{nu}) is the only realistic probe of Majorana neutrinos. In the standard scenario, dominated by light neutrino exchange, the process amplitude is proportional to m{sub ee} , the e - e element of the Majorana mass matrix. This is expected to hold true for small {beta}{beta}{nu} rates ({Gamma}{sub {beta}{beta}0{nu}}), even in the presence of new physics. Naively, current data allows for vanishing m{sub ee} , but this should be protected by an appropriate flavor symmetry. All such symmetries lead to mass matrices inconsistent with oscillation phenomenology. Hence, Majorana neutrinos imply nonzero {Gamma}{sub {beta}{beta}0{nu}}. I perform a spurion analysis to break all possible abelian symmetries that guarantee {Gamma}{sub {beta}{beta}0{nu}} = 0 and search for minimally allowed m{sub ee} values. Specifically, I survey 259 broken structures to yield m{sub ee} values and current phenomenological constraints under a variety of scenarios. This analysis also extracts predictions for both neutrino oscillation parameters and kinematic quantities. Assuming reasonable tuning levels, I find that m{sub ee} > 4 x 10{sup -6} eV at 99% confidence. Bounds below this value would indicate the Dirac neutrino nature or the existence of new light (eV-MeV scale) degrees of freedom that can potentially be probed elsewhere. This limit can be raised by improvements in neutrino parameter measurements, particularly of the reactor mixing angle, depending on the best fit parameter values. Such improvements will also significantly constrain the available model space and aid in future constructions.

  6. Discrete beta dose kernel matrices for nuclides applied in targeted radionuclide therapy (TRT) calculated with MCNP5

    SciTech Connect (OSTI)

    Reiner, Dora; Blaickner, Matthias; Rattay, Frank

    2009-11-15

    Purpose: Radiopharmaceuticals administered in targeted radionuclide therapy (TRT) rely to a great extent not only on beta-emitting nuclides but also on emitters of monoenergetic electrons. Recent advances like combined PET/CT devices, the consequential coregistration of both data, the concept of using beta couples for diagnosis and therapy, respectively, as well as the development of voxel models offer a great potential for developing TRT dose calculation systems similar to those available for external beam treatment planning. The deterministic algorithms in question for this task are based on the convolution of three-dimensional matrices, one representing the activity distribution and the other the dose point kernel. This study aims to report on three-dimensional kernel matrices for various nuclides used in TRT. Methods: The Monte Carlo code MCNP5 was used to calculate discrete dose kernels of beta particles including the contributions from their respective secondary radiation in soft tissue for the following nuclides: {sup 32}P, {sup 33}P, {sup 67}Cu, {sup 89}Sr, {sup 90}Y, {sup 103}Rh{sup m}, {sup 131}I, {sup 177}Lu, {sup 186}Re, and {sup 188}Re. For each nuclide a kernel cube of 10x10x10 mm{sup 3} was calculated, the dimensions of a voxel being 1 mm{sup 3}. Additional kernels with voxel sizes of 3x3x3 mm{sup 3} were simulated. Results: Comparison with the S-value data regarding {sup 32}P, {sup 89}Sr, {sup 90}Y, and {sup 131}I of the MIRD committee which were calculated with the EGS4 code showed a very good agreement, the secondary particle transport of {sup 90}Y being the only exception. Documented analytical kernels on the other side show deviations very close and very far to the source. Conclusions: The good accordance with the only discrete dose kernels published up to date justifies the method chosen. Together with the additional six nuclides, this report provides a considerable database for three-dimensional kernel matrices with regard to beta radionuclides applied in TRT. In contrast to analytical dose point kernels, the discrete kernels elude the problem of overestimation near the source and take energy depositions into account, which occur beyond the range of the continuous-slowing-down approximation (csda range). Recalculation of the 1x1x1 mm{sup 3} kernels to other dose kernels with varying voxel dimensions, cubic or noncubic, is shown to be easily manageable and thereby provides a resolution-independent system of dose calculation.

  7. V&V of MCNP 6.1.1 Beta Against Intermediate and High-Energy Experimental Data

    SciTech Connect (OSTI)

    Mashnik, Stepan G

    2014-09-08

    This report presents a set of validation and verification (V&V) MCNP 6.1.1 beta results calculated in parallel, with MPI, obtained using its event generators at intermediate and high-energies compared against various experimental data. It also contains several examples of results using the models at energies below 150 MeV, down to 10 MeV, where data libraries are normally used. This report can be considered as the forth part of a set of MCNP6 Testing Primers, after its first, LA-UR-11-05129, and second, LA-UR-11-05627, and third, LA-UR-26944, publications, but is devoted to V&V with the latest, 1.1 beta version of MCNP6. The MCNP6 test-problems discussed here are presented in the /VALIDATION_CEM/and/VALIDATION_LAQGSM/subdirectories in the MCNP6/Testing/directory. README files that contain short descriptions of every input file, the experiment, the quantity of interest that the experiment measures and its description in the MCNP6 output files, and the publication reference of that experiment are presented for every test problem. Templates for plotting the corresponding results with xmgrace as well as pdf files with figures representing the final results of our V&V efforts are presented. Several technical “bugs” in MCNP 6.1.1 beta were discovered during our current V&V of MCNP6 while running it in parallel with MPI using its event generators. These “bugs” are to be fixed in the following version of MCNP6. Our results show that MCNP 6.1.1 beta using its CEM03.03, LAQGSM03.03, Bertini, and INCL+ABLA, event generators describes, as a rule, reasonably well different intermediate- and high-energy measured data. This primer isn’t meant to be read from cover to cover. Readers may skip some sections and go directly to any test problem in which they are interested.

  8. Safety assessment document (SAD) for the Princeton Beta Experiment Modification (PBX-M)

    SciTech Connect (OSTI)

    Stencel, J.R.; Parsells, R.F.

    1988-04-01

    The Princeton Beta Experiment-Modification (PBX-M) is an experimental device of the tokamak type. A tokamak is characterized by a strong toroidal magnetic field composed of an externally driven component parallel to the torus centerline modified by the field produced by a transformer-driven current (OH) in the confined plasma. A second magnetic field parallel to the major toroidal axis is added to provide radial equilibrium for the plasma. As an advanced tokamak, PBX-M will have additional magnetic fields to reshape the plasma cross section from a circle into a kidney bean shape; it will also be equipped with 6MW or more of auxiliary heating power provided by four neutral beam injectors, with RF systems, and with an extensive set of diagnostics. Potential hazards associated with PBX-M, which are analyzed in this report, result from energy stored in the magnetic fields, high voltages necessary for the operation of some of the equipment and diagnostics, neutron radiation when the neutral beams are run with deuterium and x-rays, especially those emitted as a result of plasma-wall interaction. This report satisfies the requirements set forth in the PPPL Health and Safety Directives, specifically HSD-5003, and in DOE Order 5481.1B and its Chicago operations supplement (DOE86, DOE82).

  9. Trans beta substituted chlorins and methods of making and using the same

    DOE Patents [OSTI]

    Lindsey, Jonathan S.; Balasubramanian, Thiagarajan

    2003-05-06

    Trans beta substituted chlorins and methods of making the same are disclosed, along with polymers formed from or containing such trans beta substituted chlorins as one or more monomeric units therein, light harvesting rods formed from such polymers, and electrodes carrying such polymers.

  10. Production and Separation of T = 1/2 Nuclides for {beta}--{nu} angular correlation measurements

    SciTech Connect (OSTI)

    Delahaye, P.; Bajeat, O.; Saint Laurent, M. G.; Thomas, J. C.; Traykov, E.; Lienard, E.; Ban, G.; Durand, D.; Flechard, X.; Naviliat-Cuncic, O.; Stora, T.; Collaboration: GANISOL Group

    2011-11-30

    The SPIRAL facility at GANIL, which uses the so-called ISOL method to produce radioactive ion beams, is being upgraded to extend its production capabilities to the metallic beams of neutron deficient isotopes. We discuss here the potentialities offered by this upgrade for the measurement of the {beta}--{nu} angular correlation in the {beta}--decay of mirror nuclides.

  11. Characterization of a 1,4-{beta}-D-glucan synthase from Dictyostelium. Final technical report

    SciTech Connect (OSTI)

    Blanton, R.L.

    1996-02-01

    The study of cellulose biosynthesis has a long history of frustrations, false leads, and setbacks. The authors have been able to proceed further than others who have studied eukaryotic cellulose synthesis because of the high level of enzyme activity in crude membrane preparations from developing Dictyostelium cells. This has made possible experiments to study factors that influence the activity, to determine cellular localization, and to study the development regulation of the enzyme activity. In higher plants, the challenge is still to obtain highly active membrane preparations. However, they have not been able to move beyond the level of crude membranes. The high starting activity of Dictyostelium membranes gave hope that cellulose synthase activity could be purified, allowing the identification of the polypeptides involved in cellulose synthesis. The first step in the purification of a membrane-associated activity is the solubilization of the activity; this they have not yet been able to do. They have applied some of their methods developed in the study of the Dictyostelium glucan synthase to preparation of plant membranes to see if they can obtain any in vitro activity. For instance, the disruption medium, disruption methods, and assay conditions used in Dictyostelium were used to prepare plant membranes, but without obtaining significant levels of enzyme activity.

  12. Low Radioactivity Crystals for Neutrinoless Double Beta Decay Detectors

    SciTech Connect (OSTI)

    Dafinei, Ioan [Sezione INFN di Roma, P-le Aldo Moro 2, Roma I-00185 (Italy)

    2011-04-27

    The production of crystals needed for rare events physics represent a relatively new, exciting challenge in the field of materials science and engineering. Extremely low concentration of radioactive impurities and very high crystal perfection is required for the crystals to be used in experiments in which the main concerns are the reduction of the background and the use of high sensitivity detectors. A further complication is the fact that for an experiment with a significant discovery potential, relatively large quantities of crystals are needed. The present work makes a review of the general problems related to the production of crystals for rare events physics and gives details related to the production of the TeO{sub 2} crystals needed for the major experiment in this field using bolometric technique, namely the CUORE experiment. The potential use of crystals for future double beta decay experiments is also discussed.

  13. Radiopurity control in the NEXT-100 double beta decay experiment

    SciTech Connect (OSTI)

    lvarez, V.; Crcel, S.; Cervera, A.; Daz, J.; Ferrario, P.; Gil, A.; Gmez-Cadenas, J. J.; Laing, A.; Liubarsky, I.; Lorca, D.; Martn-Albo, J.; Martnez, A.; Monrabal, F.; Muoz Vidal, J.; Nebot-Guinot, M.; Rodrguez, J.; Serra, L.; Simn, A.; Sofka, C.; Sorel, M. [Instituto de Fsica Corpuscular (IFIC), CSIC and Universitat de Valncia, 46980 Paterna, Valencia (Spain)] [Instituto de Fsica Corpuscular (IFIC), CSIC and Universitat de Valncia, 46980 Paterna, Valencia (Spain); and others

    2013-08-08

    An extensive material screening and selection process is underway in the construction of the 'Neutrino Experiment with a Xenon TPC' (NEXT), intended to investigate neutrinoless double beta decay using a high-pressure xenon gas TPC filled with 100 kg of Xe enriched in {sup 136}Xe. Determination of the radiopurity levels of the materials is based on gamma-ray spectroscopy using ultra-low background germanium detectors at the Laboratorio Subterrneo de Canfranc (Spain) and also on Glow Discharge Mass Spectrometry. Materials to be used in the shielding, pressure vessel, electroluminescence and high voltage components and energy and tracking readout planes have been already taken into consideration. The measurements carried out are presented, describing the techniques and equipment used, and the results obtained are shown, discussing their implications for the NEXT experiment.

  14. Scenarios for the ATF2 Ultra-Low Betas Proposal

    SciTech Connect (OSTI)

    Marin, Eduardo; Tomas, Rogelio; Bambade, Philip; Kuroda, Shigeru; Okugi, Toshiyuki; Tauchi, Toshiaki; Terunuma, Nobuhiro; Urakawa, Junji; Parker, Brett; Seryi, Andrei; White, Glen; Woodley, Mark; /SLAC

    2012-06-29

    The current ATF2 Ultra-Low beta proposal was designed to achieve 20nm vertical IP beam size without considering the multipolar components of the FD magnets. In this paper we describe different scenarios that avoid the detrimental effect of these multipolar errors to the beam size at the interaction point (IP). The simplest approach consists in modifying the optics, but other solutions are studied as the introduction of super-conducting wigglers to reduce the emittance or the replacement of the normal-conducting focusing quadrupole in the Final Doublet (NC-QF1FF) with a super-conducting quadrupole one (SC-QF1FF). These are fully addressed in the paper.

  15. Scenarios For The ATF2 Ultra-Low Betas Proposal

    SciTech Connect (OSTI)

    Marin E.; Parker B.; Tomas R. Bambade Kuroda S. Okugi T. Tauchi T. Terunuma N. Urakawa J. Seryi A. White G. Woodley M.

    2010-05-23

    The current ATF2 Ultra-Low beta proposal was designed to achieve 20nm vertical IP beam size without considering the multipolar components of the FD magnets. In this paper we describe different scenarios that avoid the detrimental effect of these multipolar errors to the beam size at the interaction point (IP). The simplest approach consists in modifying the optics, but other solutions are studied as the introduction of super-conducting wigglers to reduce the emittance or the replacement of the normal-conducting focusing quadrupole in the Final Doublet (NC-QF1FF) with a super-conducting quadrupole one (SC-QF1FF). These are fully addressed in the paper.

  16. Nonlinear gyrokinetic theory for finite-BETA plasmas

    SciTech Connect (OSTI)

    Hahm, T.S.; Lee, W.W.; Brizard, A.

    1988-02-01

    A self-consistent and energy-conserving set of nonlinear gyrokinetic equations, consisting of the averaged Vlasov and Maxwell's equations for finite-..beta.. plasmas, is derived. The method utilized in the present investigation is based on the Hamiltonian formalism and Lie transformation. The resulting formation is valid for arbitrary values of k/perpendicular//rho//sub i/ and, therefore, is most suitable for studying linear and nonlinear evolution of microinstabilities in tokamak plasmas as well as other areas of plasma physics where the finite Larmor radius effects are important. Because the underlying Hamiltonian structure is preserved in the present formalism, these equations are directly applicable to numerical studies based on the existing gyrokinetic particle simulation techniques. 31 refs.

  17. The MAJORANA DEMONSTRATOR Neutrinoless Double-Beta Decay Experiment

    SciTech Connect (OSTI)

    Abgrall, N.; Aguayo, Estanislao; Avignone, III, F. T.; Barabash, A.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Caldwell, A. S.; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Combs, Dustin C.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Esterline, James H.; Fast, James E.; Finnerty, P.; Fraenkle, Florian; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Green, M.; Gruszko, J.; Guiseppe, Vincente; Gusev, K.; Hallin, A. L.; Hazama, R.; Hegai, A.; Henning, Reyco; Hoppe, Eric W.; Howard, Stanley; Howe, M. A.; Keeter, K.; Kidd, M. F.; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; Laferriere, Brian D.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; Luke, P.; MacMullin, S.; Martin, R. D.; Mertens, S.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; O'Shaughnessy, Mark D.; Overman, Nicole R.; Phillips, David; Poon, Alan; Pushkin, K.; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Schubert, Alexis G.; Shanks, B.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Snyder, N.; Steele, David; Strain, J.; Suriano, Anne-Marie; Thompson, J.; Timkin, V.; Tornow, Werner; Varner, R. L.; Vasilyev, Sergey; Vetter, Kai; Vorren, Kris R.; White, Brandon R.; Wilkerson, J. F.; Williams, T.; Xu, W.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir

    2014-01-01

    The Majorana Demonstrator will search for the neutrinoless double-beta (ββ (0ν)) decay of the isotope 76Ge with a mixed array of enriched and natural germanium detectors. The observation of this rare decay would indicate that the neutrino is its own antiparticle, demonstrate that lepton number is not conserved, and provide information on the absolute mass scale of the neutrino. TheDemonstrator is being assembled at the 4850-foot level of the SanfordUnderground Research Facility in Lead, SouthDakota. The array will be situated in a low-background environment and surrounded by passive and active shielding. Here we describe the science goals of the Demonstrator and the details of its design.

  18. The MAJORANA DEMONSTRATOR Neutrinoless Double-Beta Decay Experiment

    SciTech Connect (OSTI)

    Abgrall, N.; Aguayo, Estanislao; Avignone, Frank T.; Barabash, Alexander S.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Caldwell, A. S.; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Combs, Dustin C.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Esterline, James H.; Fast, James E.; Finnerty, P.; Fraenkle, Florian; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Green, M.; Gruszko, J.; Guiseppe, Vincente; Gusev, K.; Hallin, A. L.; Hazama, R.; Hegai, A.; Henning, Reyco; Hoppe, Eric W.; Howard, Stanley; Howe, M. A.; Keeter, K.; Kidd, M. F.; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; Laferriere, Brian D.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; Luke, P.; MacMullin, S.; Martin, R. D.; Mertens, S.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; O'Shaughnessy, C.; Overman, Nicole R.; Phillips, David; Poon, Alan; Pushkin, K.; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Schubert, Alexis G.; Shanks, B.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Snyder, N.; Steele, David; Strain, J.; Suriano, Anne-Marie; Thompson, J.; Timkin, V.; Tornow, Werner; Varner, R. L.; Vasilyev, Sergey; Vetter, Kai; Vorren, Kris R.; White, Brandon R.; Wilkerson, J. F.; Williams, T.; Xu, W.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir

    2014-06-01

    The MAJORANA DEMONSTRATOR will search for the neutrinoless double-beta (ββ(0ν)) decay of the isotope 76Ge with a mixed array of enriched and natural germanium detectors. The observation of this rare decay would indicate that the neutrino is its own antiparticle, demonstrate that lepton number is not conserved, and provide information on the absolute mass scale of the neutrino. The DEMONSTRATOR is being assembled at the 4850-foot level of the Sanford Underground Research Facility in Lead, South Dakota. The array will be situated in a low-background environment and surrounded by passive and active shielding. Here we describe the science goals of the DEMONSTRATOR and the details of its design.

  19. Modular low-aspect-ratio high-beta torsatron

    DOE Patents [OSTI]

    Sheffield, G.V.

    1982-04-01

    A fusion-reactor device is described which the toroidal magnetic field and at least a portion of the poloidal magnetic field are provided by a single set of modular coils. The coils are arranged on the surface of a low-aspect-ratio toroid in planed having the cylindrical coordinate relationship phi = phi/sub i/ + kz, where k is a constant equal to each coil's pitch and phi/sub i/ is the toroidal angle at which the i'th coil intersects the z = o plane. The toroid defined by the modular coils preferably has a race track minor cross section. When vertical field coils and, preferably, a toroidal plasma current are provided for magnetic-field-surface closure within the toroid, a vacuum magnetic field of racetrack-shaped minor cross section with improved stability and beta valves is obtained.

  20. The MAJORANA DEMONSTRATOR Neutrinoless Double-Beta Decay Experiment

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Abgrall, N.; Aguayo, E.; Avignone, F. T.; Barabash, A. S.; Bertrand, F. E.; Boswell, M.; Brudanin, V.; Busch, M.; Caldwell, A. S.; Chan, Y.-D.; et al

    2014-01-01

    Tmore » he M ajorana D emonstrator will search for the neutrinoless double-beta ( β β 0 ν ) decay of the isotope Ge with a mixed array of enriched and natural germanium detectors.he observation of this rare decay would indicate that the neutrino is its own antiparticle, demonstrate that lepton number is not conserved, and provide information on the absolute mass scale of the neutrino.he D emonstrator is being assembled at the 4850-foot level of the Sanford Underground Research Facility in Lead, South Dakota.he array will be situated in a low-background environment and surrounded by passive and active shielding. Here we describe the science goals of the D emonstrator and the details of its design. « less

  1. The search for Majorana neutrinos with neutrinoless double beta decays: From CUORICINO to LUCIFER experiment

    SciTech Connect (OSTI)

    Bellini, F. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma I-00185 (Italy) and INFN - Sezione di Roma, Roma I-00185 (Italy)

    2012-11-20

    The study of neutrino properties is one of the fundamental challenges in particle physics nowadays. Fifty years of investigations established that neutrinos are massive but the absolute mass scale has not yet been measured. Moreover its true nature is still unknown. Is the neutrino its own antiparticle (thus violating the lepton number) as proposed by Majorana in 1937? The only way to probe the neutrino nature is through the observation of Neutrinoless Double Beta Decay (0{nu}{beta}{beta}), a very rare spontaneous nuclear transition which emits two electrons and no neutrinos. In this paper, after a brief introduction to the theoretical framework of Majorana's neutrino, a presentation of experimental challenges posed by 0{nu}{beta}{beta} search will be given as well as an overview of present status and future perpectives of experiments.

  2. Proteomic profiling of bone marrow mesenchymal stem cells upon TGF-beta stimulation

    SciTech Connect (OSTI)

    Wang, Daojing; Park, Jennifer S.; Chu, Julia S.F.; Ari, Krakowski; Luo, Kunxin; Chen, David J.; Li, Song

    2004-08-08

    Bone marrow mesenchymal stem cells (MSCs) can differentiate into different types of cells, and have tremendous potential for cell therapy and tissue engineering. Transforming growth factor {beta}1 (TGF-{beta}) plays an important role in cell differentiation and vascular remodeling. We showed that TGF-{beta} induced cell morphology change and an increase in actin fibers in MSCs. To determine the global effects of TGF-{beta} on MSCs, we employed a proteomic strategy to analyze the effect of TGF-{beta} on the human MSC proteome. By using two-dimensional gel electrophoresis and electrospray ionization coupled to Quadrupole/time-of-flight tandem mass spectrometers, we have generated a proteome reference map of MSCs, and identified {approx}30 proteins with an increase or decrease in expression or phosphorylation in response to TGF-{beta}. The proteins regulated by TGF-{beta} included cytoskeletal proteins, matrix synthesis proteins, membrane proteins, metabolic enzymes, etc. TGF-{beta} increased the expression of smooth muscle (SM) {alpha}-actin and decreased the expression of gelsolin. Over-expression of gelsolin inhibited TGF-{beta}-induced assembly of SM {alpha}-actin; on the other hand, knocking down gelsolin expression enhanced the assembly of {alpha}-actin and actin filaments without significantly affecting {alpha}-actin expression. These results suggest that TGF-{beta} coordinates the increase of {alpha}-actin and the decrease of gelsolin to promote MSC differentiation. This study demonstrates that proteomic tools are valuable in studying stem cell differentiation and elucidating the underlying molecular mechanisms.

  3. Targeting ILK and {beta}4 integrin abrogates the invasive potential of ovarian cancer

    SciTech Connect (OSTI)

    Choi, Yoon Pyo; Kim, Baek Gil; Department of Pathology, Yonsei University College of Medicine, Seoul ; Gao, Ming-Qing; Kang, Suki; Cho, Nam Hoon

    2012-10-26

    Highlights: Black-Right-Pointing-Pointer The potential of targeting ILK and integrins for highly aggressive ovarian cancer. Black-Right-Pointing-Pointer Unanticipated synergistic effect for the combination of ILK/{beta}4 integrin. Black-Right-Pointing-Pointer Combination of ILK/{beta}4 integrin effectively inhibited the PI3K/Akt/Rac1 cascade. Black-Right-Pointing-Pointer Targeting of {beta}4 integrin/ILK had potent inhibitory effects in ovarian cancer. -- Abstract: Integrins and integrin-linked kinase (ILK) are essential to cancerous invasion because they mediate physical interactions with the extracellular matrix, and regulate oncogenic signaling pathways. The purpose of our study is to determine whether deletion of {beta}1 and {beta}4 integrin and ILK, alone or in combination, has antitumoral effects in ovarian cancer. Expression of {beta}1 and {beta}4 integrin and ILK was analyzed by immunohistochemistry in 196 ovarian cancer tissue samples. We assessed the effects of depleting these molecules with shRNAs in ovarian cancer cells by Western blot, conventional RT-PCR, cell proliferation, migration, invasion, and in vitro Rac1 activity assays, and in vivo xenograft formation assays. Overexpression of {beta}4 integrin and ILK in human ovarian cancer specimens was found to correlate with tumor aggressiveness. Depletion of these targets efficiently suppresses ovarian cancer cell proliferation, migration, and invasion in vitro and xenograft tumor formation in vivo. We also demonstrated that single depletion of ILK or combination depletion of {beta}4 integrin/ILK inhibits phosphorylation of downstream signaling targets, p-Ser 473 Akt and p-Thr202/Tyr204 Erk1/2, and activation of Rac1, as well as reduce expression of MMP-2 and MMP-9 and increase expression of caspase-3 in vitro. In conclusion, targeting {beta}4 integrin combined with ILK can instigate the latent tumorigenic potential and abrogate the invasive potential in ovarian cancer.

  4. POINT 2011: ENDF/B-VII.1 Beta2 Temperature Dependent Cross Section Library

    SciTech Connect (OSTI)

    Cullen, D E

    2011-04-07

    This report is one in the series of 'POINT' reports that over the years have presented temperature dependent cross sections for the then current version of ENDF/B. In each case I have used my personal computer at home and publicly available data and codes. I have used these in combination to produce the temperature dependent cross sections used in applications and presented in this report. I should mention that today anyone with a personal computer can produce these results. The latest ENDF/B-VII.1 beta2 data library was recently and is now freely available through the National Nuclear Data Center (NNDC), Brookhaven National Laboratory. This release completely supersedes all preceding releases of ENDF/B. As distributed the ENDF/B-VII.1 data includes cross sections represented in the form of a combination of resonance parameters and/or tabulated energy dependent cross sections, nominally at 0 Kelvin temperature. For use in our applications the ENDF/B-VII.1 library has been processed into cross sections at eight neutron reactor like temperatures, between 0 and 2100 Kelvin, in steps of 300 Kelvin (the exception being 293.6 Kelvin, for exact room temperature at 20 Celsius). It has also been processed to five astrophysics like temperatures, 1, 10, 100 eV, 1 and 10 keV. For reference purposes, 300 Kelvin is approximately 1/40 eV, so that 1 eV is approximately 12,000 Kelvin. At each temperature the cross sections are tabulated and linearly interpolable in energy. All results are in the computer independent ENDF-6 character format [R2], which allows the data to be easily transported between computers. In its processed form the POINT 2011 library is approximately 16 gigabyte in size and is distributed on one compressed DVDs (see, below for the details of the contents of each DVD).

  5. Blue Ribbon Commission, Yucca Mountain Closure, Court Actions - Future of Decommissioned Reactors, Operating Reactors and Nuclear Power - 13249

    SciTech Connect (OSTI)

    Devgun, Jas S.

    2013-07-01

    Issues related to back-end of the nuclear fuel cycle continue to be difficult for the commercial nuclear power industry and for the decision makers at the national and international level. In the US, the 1982 NWPA required DOE to develop geological repositories for SNF and HLW but in spite of extensive site characterization efforts and over ten billion dollars spent, a repository opening is nowhere in sight. There has been constant litigation against the DOE by the nuclear utilities for breach of the 'standard contract' they signed with the DOE under the NWPA. The SNF inventory continues to rise both in the US and globally and the nuclear industry has turned to dry storage facilities at reactor locations. In US, the Blue Ribbon Commission on America's Nuclear Future issued its report in January 2012 and among other items, it recommends a new, consent-based approach to siting of facilities, prompt efforts to develop one or more geologic disposal facilities, and prompt efforts to develop one or more consolidated storage facilities. In addition, the March 2011 Fukushima Daiichi accident had a severe impact on the future growth of nuclear power. The nuclear industry is focusing on mitigation strategies for beyond design basis events and in the US, the industry is in the process of implementing the recommendations from NRC's Near Term Task Force. (authors)

  6. Method of fission product beta spectra measurements for predicting reactor anti-neutrino emission

    SciTech Connect (OSTI)

    Asner, David M.; Burns, Kimberly A.; Campbell, Luke W.; Greenfield, Bryce A.; Kos, Marek S.; Orrell, John L.; Schram, Malachi; VanDevender, Brent A.; Wood, Lynn S.; Wootan, David W.

    2015-03-01

    The nuclear fission process that occurs in the core of nuclear reactors results in unstable, neutron-rich fission products that subsequently beta decay and emit electron antineutrinos. These reactor neutrinos have served neutrino physics research from the initial discovery of the neutrino to today's precision measurements of neutrino mixing angles. The prediction of the absolute flux and energy spectrum of the emitted reactor neutrinos hinges upon a series of seminal papers based on measurements performed in the 1970s and 1980s. The steadily improving reactor neutrino measurement techniques and recent reconsiderations of the agreement between the predicted and observed reactor neutrino flux motivates revisiting the underlying beta spectra measurements. A method is proposed to use an accelerator proton beam delivered to an engineered target to yield a neutron field tailored to reproduce the neutron energy spectrum present in the core of an operating nuclear reactor. Foils of the primary reactor fissionable isotopes placed in this tailored neutron flux will ultimately emit beta particles from the resultant fission products. Measurement of these beta particles in a time projection chamber with a perpendicular magnetic field provides a distinctive set of systematic considerations for comparison to the original seminal beta spectra measurements. Ancillary measurements such as gamma-ray emission and post-irradiation radiochemical analysis will further constrain the absolute normalization of beta emissions per fission. The requirements for unfolding the beta spectra measured with this method into a predicted reactor neutrino spectrum are explored.

  7. Arrested rearrangement of TCR V[beta] genes in thymocytes from children with x-linked severe combined immunodeficiency disease

    SciTech Connect (OSTI)

    Sleasman, J.W.; Harville, T.O.; White, G.B.; Barrett, D.J. ); George, J.F. ); Goodenow, M.M. Univ. of Alabama, Birmingham, AL )

    1994-07-01

    Human X-linked severe combined immunodeficiency disease (SCID) is an immunodeficiency disorder in which T cell development is arrested in the thymic cortex. B lymphocytes in children with X-linked SCID seem to differentiate normally. X-linked SCID is associated with a mutation in the gene that encodes the IL-2R [gamma]-chain. Because TCR-[beta] gene recombination is a pivotal initial event in T lymphocyte onteogeny within the thymus, the authors hypothesized that a failure to express normal IL-2R[gamma] could lead to impaired TCR-[beta] gene recombination in early thymic development. PCR was used to determine the status of TCR-[beta] gene-segment rearrangements in thymic DNA that had been obtained from children with X-linked SCID. The initial step in TCR-[beta] gene rearrangement, that of D[beta] to J[beta] recombination, was readily detected in all thymus samples from children with X-linked SCID; in contrast, V[beta] to DJ[beta] gene rearrangements were undetectable in the same samples. Both D[beta] to J[beta] and V[beta] to DJ[beta] TCR genes were rearranged in the thymic tissues obtained from immunologically normal children. The authors conclude that TCR[beta]-chain gene rearrangement is arrested in children with X-linked SCID. The results suggest a causative relationship between the failure of TCR [beta]-chain gene arrangements to proceed beyond DJ[beta] rearrangements and the production of a nonfunctional IL-2R [gamma]-chain. 45 refs., 3 figs.

  8. Site selectivity and bonding in the {beta}-phase aluminides: Studies of

    Office of Scientific and Technical Information (OSTI)

    RuAl, PdAl, and Pd and Ru dopants in NiAl (Journal Article) | SciTech Connect Site selectivity and bonding in the {beta}-phase aluminides: Studies of RuAl, PdAl, and Pd and Ru dopants in NiAl Citation Details In-Document Search Title: Site selectivity and bonding in the {beta}-phase aluminides: Studies of RuAl, PdAl, and Pd and Ru dopants in NiAl We have determined the site selectivity of Ru and Pd dopants in {beta}-phase NiAl. For both transition metal rich and poor compositions, the Ru or

  9. Pinning Down the Mechanism of Neutrinoless Double {beta} Decay with Measurements in Different Nuclei

    SciTech Connect (OSTI)

    Deppisch, Frank [Deutsches Elektronen-Synchrotron (DESY), D-22603 Hamburg (Germany); Paes, Heinrich [Department of Physics and Astronomy, University of Alabama, Tuscaloosa, Alabama 35487 (United States)

    2007-06-08

    A measurement of neutrinoless double beta decay in one isotope does not allow us to determine the underlying physics mechanism. We discuss the discrimination of mechanisms for neutrinoless double beta decay by comparing ratios of half-life measurements for different isotopes. Six prominent examples for specific new physics contributions to neutrinoless double beta decay are analyzed. We find that the change in corresponding ratios of half lives varies from 60% for supersymmetric models up to a factor of 5-20 for extra-dimensional and left-right-symmetric mechanisms.

  10. Phase-field modeling of the beta to omega phase transformation in Zr-Nb

    Office of Scientific and Technical Information (OSTI)

    alloys (Journal Article) | SciTech Connect Phase-field modeling of the beta to omega phase transformation in Zr-Nb alloys Citation Details In-Document Search Title: Phase-field modeling of the beta to omega phase transformation in Zr-Nb alloys A three-dimensional elastoplastic phase-field model is developed, using the finite element method (FEM), for modeling the athermal beta to omega phase transformation in Zr-Nb alloys by including plastic deformation and strain hardening of the material.

  11. Phase-field modeling of the beta to omega phase transformation in Zr-Nb

    Office of Scientific and Technical Information (OSTI)

    alloys (Journal Article) | SciTech Connect Phase-field modeling of the beta to omega phase transformation in Zr-Nb alloys Citation Details In-Document Search Title: Phase-field modeling of the beta to omega phase transformation in Zr-Nb alloys A three-dimensional elastoplastic phase-field model is developed, using the Finite Element Method (FEM), for modeling the athermal beta to omega phase transformation in Zr-Nb alloys by including plastic deformation and strain hardening of the material.

  12. Electromagnetic drift instabilities in high-beta plasma under conditions of a field reversed configuration

    SciTech Connect (OSTI)

    Chirkov, A. Yu.; Khvesyuk, V. I.

    2010-01-15

    Electromagnetic drift instabilities are studied in the conditions of a field reversed configuration (FRC). Dispersion equation is based on the set of Vlasov-Maxwell equations taking into account nonadiabatic responses both of ions and electrons. Considered drift instabilities are caused by density and temperature gradients. It is assumed that magnetic field of the FRC is purely poloidal. Two kinds of magnetic field nonuniformity are considered: (i) perpendicular gradient due to high beta values (beta is the plasma pressure/magnetic pressure) and (ii) curvature of magnetic lines. There is low frequency drift instability existing for high-beta regimes. Modes of such instability can propagate transversally to the unperturbed magnetic field lines.

  13. Search for Neutrinoless Double Beta Decay with the CUORE experiment

    SciTech Connect (OSTI)

    Gorla, P. [Laboratori Nazionali del Gran Sasso-INFN, S.S. 17 bis, km 18-910 67010 Assergi (Italy)

    2009-12-17

    CUORE is a next generation experiment aimed at the detection of neutrinoless Double Beta Decay of the nuclide {sup 130}Te. The experiment, which will take place in the Gran Sasso National Laboratory (Italy), will look for this rare decay using the macrobolometric technique with a prospected array of 988 detectors. Each bolometer will be constituted by a 5x5x5 cm{sup 3} TeO{sub 2} crystal, for a total mass of about 200 kg of {sup 130}Te, and will be maintained at a temperature of 10 mK. CUORE will probe the effective mass of the neutrino with a sensitivity of a few tens of meV. If an excess of counts are observed above background at the 2.5 MeV corresponding to the Q-value of the decay, CUORE will answer several questions that are still open in the field of neutrino physics, such as the determination of the particle's Majorana nature and of the absolute mass scale. A prototype for CUORE in Gran Sasso, named CUORICINO, has just closed after five years proving its importance as a stand-alone experiment.

  14. Purification of lanthanides for double beta decay experiments

    SciTech Connect (OSTI)

    Polischuk, O. G.; Barabash, A. S.; Belli, P.; Bernabei, R.; Boiko, R. S.; Danevich, F. A.; Mokina, V. M.; Poda, D. V.; Tretyak, V. I.; Cappella, F.; Incicchitti, A.; Cerulli, R.; Laubenstein, M.; Nisi, S.

    2013-08-08

    There are several potentially double beta active isotopes among the lanthanide elements. However, even high purity grade lanthanide compounds contain {sup 238}U, {sup 226}Ra and {sup 232,228}Th typically on the level of ∼ (0.1 - 1) Bq/kg. The liquid-liquid extraction technique was used to remove traces of U, Ra and Th from CeO{sub 2}, Nd{sub 2}O{sub 3} and Gd{sub 2}O{sub 3}. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe γ spectrometry at the underground Gran Sasso National Laboratories of the INFN (Italy). After the purification the radioactive contamination of gadolinium oxide by Ra and Th was decreased at least one order of magnitude. The efficiency of the approach to purify cerium oxide from Ra was on same level, while the radioactive contamination of neodymium sample before and after the purification is below the sensitivity of analytical methods. The purification method is much less efficient for chemically very similar radioactive elements like lanthanum, lutetium and actinium. R and D of the methods to remove the pollutions with improved efficiency is in progress.

  15. A High Temperature Electrochemical Energy Storage System Based on Sodium Beta-Alumina Solid Electrolyte (Base)

    SciTech Connect (OSTI)

    Anil Virkar

    2008-03-31

    This report summarizes the work done during the period September 1, 2005 and March 31, 2008. Work was conducted in the following areas: (1) Fabrication of sodium beta{double_prime} alumina solid electrolyte (BASE) using a vapor phase process. (2) Mechanistic studies on the conversion of {alpha}-alumina + zirconia into beta{double_prime}-alumina + zirconia by the vapor phase process. (3) Characterization of BASE by X-ray diffraction, SEM, and conductivity measurements. (4) Design, construction and electrochemical testing of a symmetric cell containing BASE as the electrolyte and NaCl + ZnCl{sub 2} as the electrodes. (5) Design, construction, and electrochemical evaluation of Na/BASE/ZnCl{sub 2} electrochemical cells. (6) Stability studies in ZnCl{sub 2}, SnCl{sub 2}, and SnI{sub 4} (7) Design, assembly and testing of planar stacks. (8) Investigation of the effect of porous surface layers on BASE on cell resistance. The conventional process for the fabrication of sodium ion conducting beta{double_prime}-alumina involves calcination of {alpha}-alumina + Na{sub 2}CO{sub 3} + LiNO{sub 3} at 1250 C, followed by sintering powder compacts in sealed containers (platinum or MgO) at {approx}1600 C. The novel vapor phase process involves first sintering a mixture of {alpha}-alumina + yttria-stabilized zirconia (YSZ) into a dense ceramic followed by exposure to soda vapor at {approx}1450 C to convert {alpha}-alumina into beta{double_prime}-alumina. The vapor phase process leads to a high strength BASE, which is also resistant to moisture attack, unlike BASE made by the conventional process. The PI is the lead inventor of the process. Discs and tubes of BASE were fabricated in the present work. In the conventional process, sintering of BASE is accomplished by a transient liquid phase mechanism wherein the liquid phase contains NaAlO{sub 2}. Some NaAlO{sub 2} continues to remain at grain boundaries; and is the root cause of its water sensitivity. In the vapor phase process, NaAlO{sub 2} is never formed. Conversion occurs by a coupled transport of Na{sup +} through BASE formed and of O{sup 2-} through YSZ to the reaction front. Transport to the reaction front is described in terms of a chemical diffusion coefficient of Na{sub 2}O. The conversion kinetics as a function of microstructure is under investigation. The mechanism of conversion is described in this report. A number of discs and tubes of BASE have been fabricated by the vapor phase process. The material was investigated by X-ray diffraction (XRD), optical microscopy and scanning electron microscopy (SEM), before and after conversion. Conductivity (which is almost exclusively due to sodium ion transport at the temperatures of interest) was measured. Conductivity was measured using sodium-sodium tests as well as by impedance spectroscopy. Various types of both planar and tubular electrochemical cells were assembled and tested. In some cases the objective was to determine if there was any interaction between the salt and BASE. The interaction of interest was mainly ion exchange (possible replacement of sodium ion by the salt cation). It was noted that Zn{sup 2+} did not replace Na+ over the conditions of interest. For this reason much of the work was conducted with ZnCl{sub 2} as the cathode salt. In the case of Sn-based, Sn{sup 2+} did ion exchange, but Sn{sup 4+} did not. This suggests that Sn{sup 4+} salts are viable candidates. These results and implications are discussed in the report. Cells made with Na as the anode and ZnCl{sub 2} as the cathode were successfully charged/discharged numerous times. The key advantages of the batteries under investigation here over the Na-S batteries are: (1) Steel wool can be used in the cathode compartment unlike Na-S batteries which require expensive graphite. (2) Planar cells can be constructed in addition to tubular, allowing for greater design flexibility and integration with other devices such as planar SOFC. (3) Comparable or higher open circuit voltage (OCV) than the Na-S battery. (4) Wider operating temperature range and higher temper

  16. Department of the Interior and related agencies appropriation bill, 1984. Report from the Committee on Appropriations, Senate, Ninety-Eighth Congress, First Session, Report No. 98-184

    SciTech Connect (OSTI)

    Not Available

    1983-01-01

    Information relating to changes recommended for the $6.7 billion Department of Interior (DOI) Appropriations Bill, 1984 (HR 3363) by the Senate Committee on Appropriations emphasizes Congressional efforts to limit speeding and committee concerns over some DOI procedures, especially filing declarations of taking that have received excessive court awards. The report details line-item changes in the proposed appropriations, and compares them with budget estimates and House allowances. The commtitee recommends less than the budget estimate and more than the House allowance for the overall Title I and II budgets, but both the House and Senate recommend substantial increases in the proposed land and water conservation fund. (DCK)

  17. Effect of secondary structure on the potential of mean force for poly-L-lysine in the alpha-Helix and beta-sheet conformations

    SciTech Connect (OSTI)

    Grigsby, J.J.; Blanch, H.W.; Prausnitz, J.M.

    2001-10-30

    Because poly-L-lysine (PLL) can exist in the {alpha}-helix or {beta}-sheet conformation depending on solution preparation and solution conditions, PLL is a suitable candidate to probe the dependence of protein interactions on secondary structure. The osmotic second virial coefficient and weight-average molecular weight are reported from low-angle laser-light scattering measurements for PLL as a function of NaCl concentration, pH, and {alpha}-helix or {beta}-sheet content. Interactions between PLL molecules become more attractive as salt concentration increases due to screening of PLL charge by salt ions and at low salt concentration become more attractive as pH increases due to decreased net charge on PLL. The experimental results show that interactions are stronger for the {beta}-sheet conformation than for the {alpha}-helix conformation. A spherically-symmetric model for the potential of mean force is used to account for specific interactions not described by DLVO theory and to show how differences in secondary structure affect PLL interactions.

  18. Materials and Molecular Research Division. Annual report 1981

    SciTech Connect (OSTI)

    Not Available

    1982-08-01

    Progress is reported in the areas of materials sciences, chemical sciences, nuclear sciences, fossil energy, advanced (laser) isotope separation technology, energy storage, superconducting magnets, and nuclear waste management. Work for others included phase equilibria for coal gasification products and ..beta..-alumina electrolytes for storage batteries. (DLC)

  19. Structure of active [beta]-arrestin-1 bound to a G-protein-coupled...

    Office of Scientific and Technical Information (OSTI)

    bound to a G-protein-coupled receptor phosphopeptide Citation Details In-Document Search Title: Structure of active beta-arrestin-1 bound to a G-protein-coupled ...

  20. Beta-decay spectroscopy relevant to the r-process nucleosynthesis

    SciTech Connect (OSTI)

    Nishimura, Shunji; Collaboration: RIBF Decay Collaboration

    2012-11-12

    A scientific program of beta-decay spectroscopy relevant to r-process nucleosynthesis has been started using high intensity U-beam at the RIBF. The first results of {beta}-decay half-lives of very neutron-rich Kr to Tc nuclides, all of which lie close to the r-process path, suggest a systematic enhancement of the the {beta}-decay rates of the Zr and Nb isotopes around A110 with respect to the predictions of the deformed quasiparticle-random-phase-approximation model (FRDM + QRPA). An impact of the results on the astrophysical r-process is discussed together with the future perspective of the {beta}-decay spectroscopy with the EURICA.

  1. Can one measure nuclear matrix elements of neutrinoless double {beta} decay?

    SciTech Connect (OSTI)

    Rodin, Vadim; Faessler, Amand [Institute fuer Theoretische Physik der Universitaet Tuebingen, D-72076 Tuebingen (Germany)

    2009-10-15

    By making use of the isospin conservation by strong interaction, the Fermi 0{nu}{beta}{beta} nuclear matrix element M{sub F}{sup 0{nu}} is transformed to acquire the form of an energy-weighted double Fermi transition matrix element. This useful representation allows reconstruction of the total M{sub F}{sup 0{nu}} provided a small isospin-breaking Fermi matrix element between the isobaric analog state in the intermediate nucleus and the ground state of the daughter nucleus could be measured, e.g., by charge-exchange reactions. Such a measurement could set a scale for the 0{nu}{beta}{beta} nuclear matrix elements and help to discriminate between the different nuclear structure models in which calculated M{sub F}{sup 0{nu}} may differ by as much as a factor of 5 (that translates to about 20% difference in the total M{sup 0{nu}})

  2. Method, apparatus and system for low-energy beta particle detection

    DOE Patents [OSTI]

    Akers, Douglas W.; Drigert, Mark W.

    2012-09-25

    An apparatus, method, and system relating to radiation detection of low-energy beta particles are disclosed. An embodiment includes a radiation detector with a first scintillator and a second scintillator operably coupled to each other. The first scintillator and the second scintillator are each structured to generate a light pulse responsive to interaction with beta particles. The first scintillator is structured to experience full energy deposition of low-energy beta particles, and permit a higher-energy beta particle to pass therethrough and interact with the second scintillator. The radiation detector further includes a light-to-electrical converter operably coupled to the second scintillator and configured to convert light pulses generated by the first scintillator and the second scintillator into electrical signals. The first scintillator and the second scintillator have at least one mutually different characteristic to enable an electronic system to determine whether a given light pulse is generated in the first scintillator or the second scintillator.

  3. THE FIRST H-BAND SPECTRUM OF THE MASSIVE GAS GIANT PLANET BETA...

    Office of Scientific and Technical Information (OSTI)

    THE FIRST H-BAND SPECTRUM OF THE MASSIVE GAS GIANT PLANET BETA PICTORIS b WITH THE GEMINI PLANET IMAGER Citation Details In-Document Search Title: THE FIRST H-BAND SPECTRUM OF THE ...

  4. Phase-field modeling of the beta to omega phase transformation...

    Office of Scientific and Technical Information (OSTI)

    This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and ... is developed, using the Finite Element Method (FEM), for modeling the athermal beta to ...

  5. Existing Data Format for Two-Parameter Beta-Gamma Histograms...

    Office of Scientific and Technical Information (OSTI)

    the lower energy cutoff for the betas must be considered, and the energy acceptance window must be taken into account to convert counts into activity. . 3) The RMS format has ...

  6. EXTRACTION OF TETRAVALENT PLUTONIUM VALUES FROM AQUEOUS ACID SOLUTIONS BY 2($beta$-ETHYLBUTOXY) ETHANOL

    DOE Patents [OSTI]

    Seaborg, G.T.

    1961-08-15

    A process of extracting tetnavalent plutonium from aqueous inonganic acid solutions (acidity between 1 N and pH of 2.5) with 2( beta -ethylbutoxy) ethanol is described. (AEC)

  7. Impact of sensitivity and throughput on optimum selection of a low-background alpha/beta gross counting system

    SciTech Connect (OSTI)

    Seymour, R.; Sergent, F.; Knight, K.; Kyker, B.

    1992-12-31

    Selection of the appropriate low-background counting system is determined by the laboratory`s measurement requirements including the radionuclide activities being measured, required sensitivity, sample volume, sample throughput, operator skill, automation, reporting requirements, budget, reliability, service, and upgrade capability. These requirements are ranked differently by each user. Nevertheless, any selection requires that the sensitivity and sample throughput be evaluated first because these parameters are instrument-specific, cannot be changed after the equipment is purchased and are easily quantified beforehand. Many of the other criteria are also related to sensitivity and affect the choice of instrument. Mathematical expressions, useful in evaluating sensitivity and throughput, are reviewed, extended, and applied to selecting a low-background alpha/beta counting system.

  8. Language barrier broken with Multilingual WorldWideScience.org BETA | OSTI,

    Office of Scientific and Technical Information (OSTI)

    US Dept of Energy, Office of Scientific and Technical Information Language barrier broken with Multilingual WorldWideScience.org BETA Multilingual WordWideScience Officials at the June 11 launch of Multilingual WorldWideScience.org BETA at the International Council for Scientific and Technical Information (ICSTI) annual conference held in Helsinki, Finland. Pictured, from left, Dr. Walter Warnick, U.S. Department of Energy Office of Scientific and Technical Information (OSTI) Director; Yuri

  9. Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase

    Office of Scientific and Technical Information (OSTI)

    Domain in Allosteric Regulation of Membrane Association of Proline Utilization A (Journal Article) | SciTech Connect Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A Citation Details In-Document Search Title: Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A Authors: Zhu, Weidong ; Haile,

  10. What can we learn from neutrinoless double beta decay experiments? (Journal

    Office of Scientific and Technical Information (OSTI)

    Article) | SciTech Connect What can we learn from neutrinoless double beta decay experiments? Citation Details In-Document Search Title: What can we learn from neutrinoless double beta decay experiments? × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided as a public service. Visit OSTI to utilize additional information resources in energy science and

  11. Role of short range correlations on nuclear matrix elements of neutrinoless double beta decay

    SciTech Connect (OSTI)

    Chandra, R. [Department of Applied Physics, B. B. Ambedkar University, Lucknow - 226025 (India); Chaturvedi, K. [Department of Physics, Bundelkhand University, Jhansi-284128 (India); Rath, P. K. [Department of Physics, University of Lucknow, Lucknow-226007 (India); Raina, P. K. [Department of Physics, Indian Institute of Technology, Ropar, Rupnagar - 140001, Punjab (India)

    2011-11-23

    Employing four different parametrization of the pairing plus multipolar type of effective two-body interaction and three different parametrizations of Jastrow-type of short range correlations, the uncertainties in the nuclear transition matrix elements due to the exchange of light as well as heavy Majorana neutrino for the 0{sup +}{yields}0{sup +} transition of neutrinoless positron {beta}{beta} decay are estimated in the PHFB model.

  12. Method and apparatus for selective capture of gas phase analytes using metal .beta.-diketonate polymers

    DOE Patents [OSTI]

    Harvey, Scott D [Kennewick, WA

    2011-06-21

    A process and sensor device are disclosed that employ metal .beta.-diketonate polymers to selectively capture gas-phase explosives and weaponized chemical agents in a sampling area or volume. The metal .beta.-diketonate polymers can be applied to surfaces in various analytical formats for detection of: improvised explosive devices, unexploded ordinance, munitions hidden in cargo holds, explosives, and chemical weapons in public areas.

  13. Discovery of a 210 -fiber texture in medical-grade metastable beta titanium wire

    SciTech Connect (OSTI)

    Cai, Song; Schaffer, Jeremy E.; Ren, Yang; Daymond, Mark R.

    2015-04-01

    The texture and phase evolution of metastable beta-III Ti alloy wires, produced in a medical-grade wire-processing facility, are examined via synchrotron X-ray diffraction. The texture development in the beta-phase was interpreted by a simple viscoplastic self-consistent (VPSC) modeling approach. Both the stress-induced martensite and stress-induced omega phase transformations are observed during the early stage of cold deformation. The < 1 1 0 >(beta) texture is gradually replaced by the < 2 1 0 >(beta) texture at cold work levels above 50% total area reduction or equivalently 0.70 axial true strain. Formation of the < 2 1 0 >(beta)-fiber from the combined activity of {1 1 2} and {3 3 2} twinning plus conventional slip is observed and may not directly depend upon the stress-induced phase per se. According to the VPSC model, similar texture should occur in other metastable beta-Ti alloys subjected to similar wire processing. These data should help inform process-structure-function towards better wire design in titanium-based medical devices. (C) 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved

  14. Preparation of powders suitable for conversion to useful .beta.-aluminas

    DOE Patents [OSTI]

    Morgan, Peter E. D.

    1982-01-01

    A process for forming a precursor powder which, when suitably pressed and sintered forms highly pure, densified .beta.- or .beta."-alumina, comprising the steps of: (1) forming a suspension (or slurry) of Bayer-derived Al(OH).sub.3 in a water-miscible solvent; (2) adding an aqueous solution of a Mg compound, a Li compound, a Na compound or mixtures thereof to the Bayer-derived Al(OH).sub.3 suspension while agitating the mixture formed thereby, to produce a gel; (3) drying the gel at a temperature above the normal boiling point of water to produce a powder material; (4) lightly ball milling and sieving said powder material; and (5) heating the ball-milled and sieved powder material at a temperature of between 350.degree. to 900.degree. C. to form the .beta.- or .beta."-alumina precursor powder. The precursor powder, thus formed, may be subsequently isopressed at a high pressure and sintered at an elevated temperature to produce .beta.- or .beta."-alumina. BACKGROUND OF THE INVENTION

  15. Failure of the gross theory of beta decay in neutron deficient nuclei

    SciTech Connect (OSTI)

    Firestone, R. B.; Schwengner, R.; Zuber, K.

    2015-05-28

    The neutron deficient isotopes 117-121Xe, 117-124Cs, and 122-124Ba were produced by a beam of 28Si from the LBNL SuperHILAC on a target of natMo. The isotopes were mass separated and their beta decay schemes were measured with a Total Absorption Spectrometer (TAS). The beta strengths derived from these data decreased dramatically to levels above ?1 MeV for the even-even decays; 34 MeV for even-Z, odd-N decays; 45 MeV for the odd-Z, even-N decays; and 78 MeV for the odd-Z, odd-N decays. The decreasing strength to higher excitation energies in the daughters contradicts the predictions of the Gross Theory of Beta Decay. The integrated beta strengths are instead found to be consistent with shell model predictions where the single-particle beta strengths are divided amoung many low-lying levels. The experimental beta strengths determined here have been used calculate the half-lives of 143 neutron deficient nuclei with Z=5164 to a precision of 20% with respect to the measured values.

  16. Sense and sensitivity of double beta decay experiments

    SciTech Connect (OSTI)

    Gmez-Cadenas, J.J.; Martn-Albo, J.; Sorel, M.; Ferrario, P.; Monrabal, F.; Muoz, J. [Instituto de Fsica Corpuscular (IFIC), CSIC and Universidad de Valencia, Calle Catedrtico Jos Beltrn 2, 46071 Valencia (Spain); Novella, P. [Centro de Investigaciones Energticas, Medioambientales y Tecnolgicas (CIEMAT), Avda. Complutense 22, 28040 Madrid (Spain); Poves, A., E-mail: gomez@mail.cern.ch, E-mail: justo.martin-albo@ific.uv.es, E-mail: sorel@ific.uv.es, E-mail: paola.ferrario@ific.uv.es, E-mail: francesc.monrabal@ific.uv.es, E-mail: jmunoz@ific.uv.es, E-mail: pau.novella@ciemat.es, E-mail: alfredo.poves@uam.es [Dpto. de de Fsica Terica and IFT-UAM/CSIC, Universidad Autnoma de Madrid, Calle Nicols Cabrera 13-15, 28049 Madrid (Spain)

    2011-06-01

    The search for neutrinoless double beta decay is a very active field in which the number of proposals for next-generation experiments has proliferated. In this paper we attempt to address both the sense and the sensitivity of such proposals. Sensitivity comes first, by means of proposing a simple and unambiguous statistical recipe to derive the sensitivity to a putative Majorana neutrino mass, m{sub ??}. In order to make sense of how the different experimental approaches compare, we apply this recipe to a selection of proposals, comparing the resulting sensitivities. We also propose a ''physics-motivated range'' (PMR) of the nuclear matrix elements as a unifying criterium between the different nuclear models. The expected performance of the proposals is parametrized in terms of only four numbers: energy resolution, background rate (per unit time, isotope mass and energy), detection efficiency, and ?? isotope mass. For each proposal, both a reference and an optimistic scenario for the experimental performance are studied. In the reference scenario we find that all the proposals will be able to partially explore the degenerate spectrum, without fully covering it, although four of them (KamLAND-Zen, CUORE, NEXT and EXO) will approach the 50 meV boundary. In the optimistic scenario, we find that CUORE and the xenon-based proposals (KamLAND-Zen, EXO and NEXT) will explore a significant fraction of the inverse hierarchy, with NEXT covering it almost fully. For the long term future, we argue that {sup 136}Xe-based experiments may provide the best case for a 1-ton scale experiment, given the potentially very low backgrounds achievable and the expected scalability to large isotope masses.

  17. Review and analysis of proposed EPA groundwater standards for the UMTRA Project. Summary report

    SciTech Connect (OSTI)

    Not Available

    1987-10-01

    The Title I groundwater standards for inactive uranium mill tailings sites, which were promulgated on January 5, 1983, by the US Environmental Protection Agency (EPA) for the Uranium Mill Tailings Remedial Action (UMTRA) Project, were remanded to the EPA on September 3, 1985, by the US Tenth Circuit Court of Appeals. The Court instructed the EPA to compile general groundwater standards for all sites. On September 24, 1987, the EPA published proposed standards in response to the remand. This Summary Report includes an evaluation of the potential effects of the proposed EPA groundwater standards on the UMTRA Project as well as a discussion of the DOE`s position on the proposed standards. This report is accompanied by a detailed Technical Report and Appendices which provide supporting information and analyses. This Summary Report results from a study undertaken to: determine the impact of the proposed standards on the UMTRA Project; and recommend provisions for the implementation of the final standards that will minimize adverse impact to the conduct of the UMTRA Project while ensuring protection of human health and the environment. Specifically, the following were considered: the flexibility of the proposed standards; interpretations of the proposed standards; the extent of aquifer restoration that may be required to implement the proposed standards at each site; the costs of aquifer restoration; and design changes necessary to meet the standards.

  18. Annual Reports - SRSCRO

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    reports Annual Reports Annual Report 2015 Annual Report 2014 Annual Report 2013 Annual Report 2012 Annual Report 2011 Annual Report 2010 Annual Report 2009 Annual Report 2008...

  19. SU-E-J-03: A Comprehensive Comparison Between Alpha and Beta Emitters for Cancer Radioimmunotherapy

    SciTech Connect (OSTI)

    Huang, C.Y.; Guatelli, S; Oborn, B; Allen, B

    2014-06-01

    Purpose: The purpose of this study is to perform a comprehensive comparison of the therapeutic efficacy and cytotoxicity of alpha and beta emitters for Radioimmunotherapy (RIT). For each stage of cancer development, specific models were built for the separate objectives of RIT to be addressed:a) kill isolated cancer cells in transit in the lymphatic and vascular circulation,b) regress avascular cell clusters,c) regress tumor vasculature and tumors. Methods: Because of the nature of short range, high LET alpha and long energy beta radiation and heterogeneous antigen expression among cancer cells, the microdosimetric approach is essential for the RIT assessment. Geant4 based microdosimetric models are developed for the three different stages of cancer progression: cancer cells, cell clusters and tumors. The energy deposition, specific energy resulted from different source distribution in the three models was calculated separately for 4 alpha emitting radioisotopes ({sup 211}At, {sup 213}Bi, {sup 223}Ra and {sup 225}Ac) and 6 beta emitters ({sup 32}P, {sup 33}P, {sup 67}Cu, {sup 90}Y, {sup 131}I and {sup 177}Lu). The cell survival, therapeutic efficacy and cytotoxicity are determined and compared between alpha and beta emitters. Results: We show that internal targeted alpha radiation has advantages over beta radiation for killing isolated cancer cells, regressing small cell clusters and also solid tumors. Alpha particles have much higher dose specificity and potency than beta particles. They can deposit 3 logs more dose than beta emitters to single cells and solid tumor. Tumor control probability relies on deep penetration of radioisotopes to cancer cell clusters and solid tumors. Conclusion: The results of this study provide a quantitative understanding of the efficacy and cytotoxicity of RIT for each stage of cancer development.

  20. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2001-01-01

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4 , ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5, is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH , --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  1. Methods for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2003-12-09

    A method for labeling .beta.-amyloid plaques and neurofibrillary tangles in vivo and in vitro, comprises contacting a compound of formula (I): ##STR1## with mammalian tissue. In formula (I), R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2 -alkyl, --C.dbd.C(CN).sub.2 -alkylenyl-R.sub.4, ##STR2## R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4 ; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 ; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S. R.sub.2 and R.sub.3 are each independently selected from the group consisting of alkyl and alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal and spiperone-3-yl. Alternatively, R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkylenyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl. In the compounds of formula (I), one or more of the hydrogen, halogen or carbon atoms can, optionally, be replaced with a radiolabel.

  2. Compositions for labeling .beta.-amyloid plaques and neurofibrillary tangles

    DOE Patents [OSTI]

    Barrio, Jorge R.; Petric, Andrej; Satyamurthy, Nagichettiar; Small, Gary W.; Cole, Gregory M.; Huang, Sung-Cheng

    2008-03-11

    Compositions useful for labeling .beta.-amyloid plaques and neurofibrillary tangles are provided. The compositions comprises compounds of formula (I): ##STR00001## wherein R.sub.1 is selected from the group consisting of --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C.dbd.C(CN).sub.2-alkyl, --C.dbd.C(CN).sub.2-alkylenyl-R.sub.4, ##STR00002## wherein R.sub.4 is a radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl; R.sub.5 is a radical selected from the group consisting of --NH.sub.2, --OH, --SH, --NH-alkyl, --NHR.sub.4, --NH-alkylenyl-R.sub.4, --O-alkyl, --O-alkylenyl-R.sub.4, --S-alkyl, and --S-alkylenyl-R.sub.4; R.sub.6 is a radical selected from the group consisting of --CN, --COOH, --C(O)O-alkyl, --C(O)O-alkylenyl-R.sub.4, --C(O)-alkyl, --C(O)-alkylenyl-R.sub.4, --C(O)-halogen, --C(O)NH-alkyl, --C(O)NH-alkylenyl-R.sub.4 and --C(O)NH.sub.2; R.sub.7 is a radical selected from the group consisting of O, NH, and S; and R.sub.8 is N, O or S; and R.sub.2 is selected from the group consisting of alkyl and alkylenyl-R.sub.10 and R.sub.3 is alkylenyl-R.sub.10, wherein R.sub.10 is selected from the group consisting of --OH, --OTs, halogen, spiperone, spiperone ketal, and spiperone-3-yl, or R.sub.2 and R.sub.3 together form a heterocyclic ring, optionally substituted with at least one radical selected from the group consisting of alkyl, alkoxy, OH, OTs, halogen, alkyl-R.sub.10, carbonyl, spiperone, spiperone ketal and spiperone-3-yl, and further wherein one or more of the hydrogen, halogen or carbon atoms are optionally replaced with a radiolabel.

  3. The FBXW7 {beta}-form is suppressed in human glioma cells

    SciTech Connect (OSTI)

    Gu, Zhaodi; Inomata, Kenichi; Ishizawa, Kota; Horii, Akira . E-mail: horii@mail.tains.tohoku.ac.jp

    2007-03-23

    FBXW7 (F-box and WD40 domain protein 7) is an F-box protein with 7 tandem WDs (tryptophan-aspartic acid) that functions as a phosphoepitope-specific substrate recognition component of SCF (Skp1-Cul1-F-box protein) ubiquitin ligases and catalyzes the ubiquitination of proteins promoting cell proliferation, such as CCNE1, MYC, AURKA, NOTCH1, and JUN, which are frequently activated in a wide range of human cancers. FBXW7 is a candidate tumor suppressor, and mutations have been reported in some human tumors. In this study, we analyzed 84 human tumor cell lines in search for genetic alterations of FBXW7, as well as mRNA and protein expressional changes, and compared them with expression levels of the CCNE1, MYC, and AURKA proteins. We found a novel nonsense mutation in a colon cancer cell line SCC and confirmed the missense mutations in SKOV3, an ovarian cancer cell line, and LoVo, a colon cancer cell line. Moreover, suppressed expression of FBXW7 accompanied by activation of the target proteins were observed in ovarian, colon, endometrial, gastric, and prostate cancers. It is notable that highly suppressed mRNA expression of the FBXW7 {beta}-form was found in all the human glioma cell lines analyzed; enhanced expressions of CCNE1, MYC, and AURKA were observed in these cells. Our present results imply that FBXW7 plays a pivotal role in many tissues by controlling the amount of cell cycle promoter proteins and that dysfunction of this protein is one of the essential steps in carcinogenesis in multiple organs.

  4. F{sub o}F{sub 1}-ATPase activity regulated by external links on {beta} subunits

    SciTech Connect (OSTI)

    Cheng, Jie; Zhang, Xiao-ai; Graduate School of the Chinese Academy of Sciences, Beijing 100049 ; Shu, Yao-Gen; Yue, Jia-Chang

    2010-01-01

    F{sub o}F{sub 1}-ATPase activity is regulated by external links on {beta} subunits with different molecular weight. It is inhibited when anti-{beta} subunit antibody, streptavidin and H9 antibody link on the {beta} subunits successively, but is activated when virus was binded. Western blotting indicated that the employed anti-{beta} antibody target was on the non-catalytic site of the {beta} subunit. Furthermore, an ESR study of spin-labeled ATP (SL-ATP) showed that the affinity of ATP to the holoenzyme increases with increasing external links on the {beta} subunits. This simple regulation method may have great potential in the design of rapid, free labeled, sensitive and selective biosensors.

  5. Minimally allowed neutrinoless double beta decay rates from approximate flavor symmetries

    SciTech Connect (OSTI)

    Jenkins, James [Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States) and Northwestern University, Department of Physics and Astronomy, Evanston, Illinois 60208 (United States)

    2009-06-01

    Neutrinoless double beta decay ({beta}{beta}0{nu}) is among the only realistic probes of Majorana neutrinos. In the standard scenario, dominated by light neutrino exchange, the process amplitude is proportional to m{sub ee}, the e-e element of the Majorana mass matrix. Naively, current data allow for vanishing m{sub ee}, but this should be protected by an appropriate flavor symmetry. All such symmetries lead to mass matrices inconsistent with oscillation phenomenology. I perform a spurion analysis to break all possible Abelian symmetries that guarantee vanishing {beta}{beta}0{nu} rates and search for minimally allowed values. I survey 230 broken structures to yield m{sub ee} values and current phenomenological constraints under a variety of scenarios. This analysis also extracts predictions for both neutrino oscillation parameters and kinematic quantities. Assuming reasonable tuning levels, I find that m{sub ee}>4x10{sup -6} eV at 99% confidence. Bounds below this value might indicate the Dirac neutrino nature or the existence of new light (eV-MeV scale) degrees of freedom that can potentially be probed elsewhere.

  6. Minimally allowed neutrinoless double beta decay rates within an anarchical framework

    SciTech Connect (OSTI)

    Jenkins, James [Northwestern University, Department of Physics and Astronomy, 2145 Sheridan Road, Evanston, Illinois 60208 (United States)

    2009-06-01

    Neutrinoless double beta decay ({beta}{beta}0{nu}) is the only realistic probe of the Majorana nature of the neutrino. In the standard picture, its rate is proportional to m{sub ee}, the e-e element of the Majorana neutrino mass matrix in the flavor basis. I explore minimally allowed m{sub ee} values within the framework of mass matrix anarchy where neutrino parameters are defined statistically at low energies. Distributions of mixing angles are well defined by the Haar integration measure, but masses are dependent on arbitrary weighting functions and boundary conditions. I survey the integration measure parameter space and find that for sufficiently convergent weightings, m{sub ee} is constrained between (0.01-0.4) eV at 90% confidence. Constraints from neutrino mixing data lower these bounds. Singular integration measures allow for arbitrarily small m{sub ee} values with the remaining elements ill-defined, but this condition constrains the flavor structure of the model's ultraviolet completion. {beta}{beta}0{nu} bounds below m{sub ee}{approx}5x10{sup -3} eV should indicate symmetry in the lepton sector, new light degrees of freedom, or the Dirac nature of the neutrino.

  7. Advanced materials for sodium-beta alumina batteries: Status, challenges and perspectives

    SciTech Connect (OSTI)

    Lu, XC; Xia, GG; Lemmon, JP; Yang, ZG

    2010-05-01

    The increasing penetration of renewable energy and the trend toward clean, efficient transportation have spurred growing interests in sodium-beta alumina batteries that store electrical energy via sodium ion transport across a beta ''-Al(2)O(3) solid electrolyte at elevated temperatures (typically 300-350 degrees C ). Currently, the negative electrode or anode is metallic sodium in molten state during battery operation; the positive electrode or cathode can be molten sulfur (Na-S battery) or solid transition metal halides plus a liquid phase secondary electrolyte (e.g., ZEBRA battery). Since the groundbreaking works in the sodium-beta alumina batteries a few decades ago, encouraging progress has been achieved in improving battery performance, along with cost reduction. However, there remain issues that hinder broad applications and market penetration of the technologies. To better the Na-beta alumina technologies require further advancement in materials along with component and system design and engineering. This paper offers a comprehensive review on materials of electrodes and electrolytes for the Na-beta alumina batteries and discusses the challenges ahead for further technology improvement. (C) 2009 Published by Elsevier B.V.

  8. Effects of thyroid hormone on. beta. -adrenergic responsiveness of aging cardiovascular systems

    SciTech Connect (OSTI)

    Tsujimoto, G.; Hashimoto, K.; Hoffman, B.B.

    1987-03-01

    The authors have compared the effects of ..beta..-adrenergic stimulation on the heart and peripheral vasculature of young (2-mo-old) and older (12-mo-old) rats both in the presence and absence of triiodothyronine (T/sub 3/)-induced hyperthyroidism. The hemodynamic consequences of T/sub 3/ treatment were less prominent in the aged hyperthyroid rats compared with young hyperthyroid rats (both in intact and pithed rats). There was a decrease in sensitivity of chronotropic responsiveness to isoproterenol in older pithed rats, which was apparently reversed by T/sub 3/ treatment. The number and affinity of myocardial ..beta..-adrenergic receptor sites measured by (/sup 125/I)cyanopindolol were not significantly different in young and older control rats; also, ..beta..-receptor density increased to a similar extent in both young and older T/sub 3/-treated rats. The ability of isoproterenol to relax mesenteric arterial rings, markedly blunted in older rats, was partially restored by T/sub 3/ treatment without their being any change in isoproterenol-mediated relaxation in the arterial preparation from young rats. The number and affinity of the ..beta..-adrenergic receptors measured in the mesenteric arteries was unaffected by either aging or T/sub 3/ treatment. The data suggest that effects of thyroid hormone and age-related alterations of cardiovascular responsiveness to ..beta..-adrenergic stimulation are interrelated in a complex fashion with a net result that the hyperkinetic cardiovascular manifestations in hyperthyroidism are attenuated in the older animals.

  9. Failure of the gross theory of beta decay in neutron deficient nuclei

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Firestone, R. B.; Schwengner, R.; Zuber, K.

    2015-05-28

    The neutron deficient isotopes 117-121Xe, 117-124Cs, and 122-124Ba were produced by a beam of 28Si from the LBNL SuperHILAC on a target of natMo. The isotopes were mass separated and their beta decay schemes were measured with a Total Absorption Spectrometer (TAS). The beta strengths derived from these data decreased dramatically to levels above ≈1 MeV for the even-even decays; 3–4 MeV for even-Z, odd-N decays; 4–5 MeV for the odd-Z, even-N decays; and 7–8 MeV for the odd-Z, odd-N decays. The decreasing strength to higher excitation energies in the daughters contradicts the predictions of the Gross Theory of Betamore » Decay. The integrated beta strengths are instead found to be consistent with shell model predictions where the single-particle beta strengths are divided amoung many low-lying levels. The experimental beta strengths determined here have been used calculate the half-lives of 143 neutron deficient nuclei with Z=51–64 to a precision of 20% with respect to the measured values.« less

  10. Find Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reports Find Reports Most of the reports sources below are publicly accessible. Question? 667-5809 Email Unclassified Los Alamos Reports Library Catalog - Print and electronic (1943-present) Los Alamos Authors (LANL-only access) - LA-, LA-CP, and LA-UR reports (1973-present) Los Alamos Research Online - Find published versions of Los Alamos research (2006-present) Classified reports - contact the SI-RMS Technical Report Collection for an appointment: phone icon 5-4168 / email icon

  11. Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor Beta Chain

    SciTech Connect (OSTI)

    Fernandez, M.M.; Robinson, H.; Cho, S.; De Marzi, M. C.; Kerzic, M. C.; Mariuzza, R. A.; Malchiodi, E. L.

    2011-01-14

    Superantigens (SAgs) are bacterial or viral toxins that bind MHC class II (MHC-II) molecules and T-cell receptor (TCR) in a nonconventional manner, inducing T-cell activation that leads to inflammatory cytokine production, which may result in acute toxic shock. In addition, the emerging threat of purpura fulminans and community-associated meticillin-resistant Staphylococcus aureus emphasizes the importance of a better characterization of SAg binding to their natural ligands that may allow the development of reagents to neutralize their action. The three-dimensional structure of the complex between a mouse TCR {beta} chain (mV{beta}8.2) and staphylococcal enterotoxin G (SEG) at 2.0 {angstrom} resolution revealed a binding site that does not conserve the 'hot spots' present in mV{beta}8.2-SEC2, mV{beta}8.2-SEC3, mV{beta}8.2-SEB, and mV{beta}8.2-SPEA complexes. Analysis of the mV{beta}8.2-SEG interface allowed us to explain the higher affinity of this complex compared with the others, which may account for the early activation of T-cells bearing mV{beta}8.2 by SEG. This mode of interaction between SEG and mV{beta}8.2 could be an adaptive advantage to bestow on the pathogen a faster rate of colonization of the host.

  12. Beta-Amyloid Deposition and Alzheimer's Type Changes Induced by Borrelia Spirochetes

    SciTech Connect (OSTI)

    Miklossy,J.; Kis, A.; Radenovic, A.; Miller, L.; Forro, L.; Martins, R.; Reiss, K.; Darbinian, N.; Darekar, P.; et al.

    2006-01-01

    The pathological hallmarks of Alzheimer's disease (AD) consist of {beta}-amyloid plaques and neurofibrillary tangles in affected brain areas. The processes, which drive this host reaction are unknown. To determine whether an analogous host reaction to that occurring in AD could be induced by infectious agents, we exposed mammalian glial and neuronal cells in vitro to Borrelia burgdorferi spirochetes and to the inflammatory bacterial lipopolysaccharide (LPS). Morphological changes analogous to the amyloid deposits of AD brain were observed following 2-8 weeks of exposure to the spirochetes. Increased levels of {beta}-amyloid presursor protein (A{beta}PP) and hyperphosphorylated tau were also detected by Western blots of extracts of cultured cells that had been treated with spirochetes or LPS. These observations indicate that, by exposure to bacteria or to their toxic products, host responses similar in nature to those observed in AD may be induced.

  13. Nuclear Shell Model Analyses and Predictions of Double-Beta Decay Observables

    SciTech Connect (OSTI)

    Horoi, Mihai [Department of Physics, Central Michigan University, Mount Pleasant, Michigan, 48859 (United States)

    2010-11-24

    Recent results from neutrino oscillation experiments have convincingly demonstrated that neutrinos have mass and they can mix. The neutrinoless double beta decay is the most sensitive process to determine the absolute scale of the neutrino masses, and the only one that can distinguish whether neutrino is a Dirac or a Majorana particle. A key ingredient for extracting the absolute neutrino masses from neutrinoless double beta decay experiments is a precise knowledge of the nuclear matrix elements (NME) for this process. Newly developed shell model approaches for computing the NME and half-lifes for the two-neutrino and neutrinoless double beta decay modes using modern effective interactions are presented. The implications of the new results on the experimental limits of the effective neutrino mass are discussed by comparing the decays of {sup 48}Ca and {sup 76}Ge.

  14. Disentangling the various Mechanisms of neutrinoless double beta decay to extract the neutrino mass

    SciTech Connect (OSTI)

    Vergados, J. D. [Physics Department, University of Ioannina, Ioannina, GR 451 10, Greece and Theory Division, CERN 1211, Geneva 23 (Greece)

    2011-12-16

    It is well known that there exist many mechanisms that may contribute to neutrinoless double beta decay. By exploiting the fact that the associated nuclear matrix elements are target dependent we show that, given definite experimental results on a sufficient number of targets, one can determine or sufficiently constrain all lepton violating parameters including the mass term. As a specific example we show that, given the observation of the 0{nu}{beta}{beta}-decay in three different nuclei, e.g. {sup 76}Ge, {sup 100}Mo and {sup 130}Te, and assuming just three active lepton number violating parameters, e.g. light and heavy neutrino mass mechanisms in left handed currents as well as R-parity breaking SUSY mechanism, one may determine all lepton violating parameters, provided that they are relatively real.

  15. Method of increasing radiation sensitivity by inhibition of beta one integrin

    DOE Patents [OSTI]

    Park, Catherine; Bissell, Mina J.

    2009-11-17

    A method for increasing or monitoring apoptosis in tumor cells by the co-administration of ionizing radiation and an anti-integrin antibody. Increasing apoptosis reduces tumor growth in vivo and in a cell culture model. The antibody is directed against the beta-1 integrin subunit and is inhibitory of beta-1 integrin signaling. Other molecules having an inhibitory effect on beta-1 integrin, either in signaling or in binding to its cognate extracellular receptors may also be used. The present method is particularly of interest in treatment of tumor cells associated with breast cancer, wherein radiation is currently used alone. The present method further contemplates a monoclonal antibody suitable for human administration that may further comprise a radioisotope attached thereto.

  16. Correlation measurements in nuclear {beta}-decay using traps and polarized low energy beams

    SciTech Connect (OSTI)

    Naviliat-Cuncic, Oscar

    2013-05-06

    Precision measurements in nuclear {beta}-decay provide sensitive means to test discrete symmetries in the weak interaction and to determine some of the fundamental constants in semi-leptonic decays, like the coupling of the lightest quarks to charged weak bosons. The main motivation of such measurements is to find deviations from Standard Model predictions as possible indications of new physics. In this contribution I will focus on two topics related to precision measurements in nuclear {beta}-decay: i) the determination of the V{sub ud} element of the Cabibbo-Kobayashi-Maskawa quark mixing matrix from nuclear mirror transitions and ii) the search for exotic scalar or tensor contributions from {beta}{nu} angular correlations. The purpose is to underline the role being played by experimental techniques based on the confinement of radioactive species with atom and ion traps as well as the plans to use low energy polarized beams.

  17. MHD instabilities and their control in high-beta plasmas in KSTAR

    SciTech Connect (OSTI)

    In, Yongkyoon

    2013-02-06

    We established 3 specific tasks as follows: Task 1 - Investigate the MHD activity during the current ramp-up phase with shaped plasmas; Task 2 - Develop a theoretical model that may show the hollowness dependent instability; Task 3 - Explore the beta-limiting instabilities. To address each task, FAR-TECH actively participated in the 2012 KSTAR run-campaign, which helped us make productive progress. Specifically, the shaping dependence of MHD activity during current ramp-up phase was investigated using dedicated run-time in KSTAR (October 4 and 9, 2012), which was also attempted to address the hollowness of temperature (or pressure) profiles. Also, a performance-limiting disruption, which occurred in a relatively high intermediate beta plasma (shot 7110) in KSTAR ({beta}{sub N} ~ 1.7), was studied, and the preliminary analysis shows that the disruption might not be stability-limited but likely density-limited.

  18. The MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-beta Decay of Germanium-76

    SciTech Connect (OSTI)

    Schubert, Alexis G.; Aguayo, Estanislao; Avignone, F. T.; Zhang, C.; Back, Henning O.; Barabash, Alexander S.; Bergevin, M.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Collar, J. I.; Combs, Dustin C.; Cooper, R. J.; Detwiler, Jason A.; Leon, Jonathan D.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Esterline, James H.; Fast, James E.; Fields, N.; Finnerty, P.; Fraenkle, Florian; Gehman, Victor M.; Giovanetti, G. K.; Green, M.; Guiseppe, Vincente; Gusey, K.; Hallin, A. L.; Hazama, R.; Henning, Reyco; Hime, Andrew; Hoppe, Eric W.; Horton, Mark; Howard, Stanley; Howe, Mark; Johnson, R. A.; Keeter, K.; Keillor, Martin E.; Keller, C.; Kephart, Jeremy D.; Kidd, M. F.; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; LaFerriere, Brian D.; LaRoque, B. H.; Leviner, L.; Loach, J. C.; MacMullin, S.; Marino, Michael G.; Martin, R. D.; Mei, Dong-Ming; Merriman, Jason H.; Miller, M. L.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; Overman, Nicole R.; Phillips, D.; Poon, Alan; Perumpilly, Gopakumar; Prior, Gersende; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Sobolev, V.; Steele, David; Strain, J.; Thomas, K.; Timkin, V.; Tornow, Werner; Vanyushin, I.; Varner, R. L.; Vetter, Kai; Vorren, Kris R.; Wilkerson, J. F.; Wolfe, B. A.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir

    2012-09-28

    The observation of neutrinoless double-beta decay would determine whether the neutrino is a Majorana particle and provide information on the absolute scale of neutrino mass. The MAJORANA Collaboration is constructing the DEMONSTRATOR, an array of germanium detectors, to search for neutrinoless double-beta decay of 76Ge. The DEMONSTRATOR will contain 40 kg of germanium; up to 30 kg will be enriched to 86% in 76Ge. The DEMONSTRATOR will be deployed deep underground in an ultra-low-background shielded environment. Operation of the DEMONSTRATOR aims to determine whether a future tonne-scale germanium experiment can achieve a background goal of one count per tonne-year in a 4-keV region of interest around the 76Ge neutrinoless double-beta decay Q-value of 2039 keV.

  19. Characterization of the {beta}-phase of the palladium-hydrogen equation of state

    SciTech Connect (OSTI)

    Fisher, K.J.

    1998-07-01

    The {beta}-phase of the P-C-T curves of the palladium-hydrogen system is encountered at high pressures of gaseous hydrogen and low temperatures of this system. The {beta}-phase is characterized by an increase in the concentration of hydrogen in the palladium lattice with an increase in pressure of the free hydrogen gas surrounding the palladium. The P-C-T curves in this study are determined by gravimetric measurements of the hydrided palladium sample to determine the amount of hydrogen within the palladium lattice. The amount of hydrogen is kept constant within the experimental system and the temperature is varied which changes the pressures. The objective of this experimental thesis is to accurately determine the P-C-T curves of palladium in the {beta}-phase region to pressures of 20,000 psia and medium to low temperature region of {minus}60 C to 100 C.

  20. Ionizing radiation predisposes non-malignant human mammaryepithelial cells to undergo TGF beta-induced epithelial to mesenchymaltransition

    SciTech Connect (OSTI)

    Andarawewa, Kumari L.; Erickson, Anna C.; Chou, William S.; Costes, Sylvain; Gascard, Philippe; Mott, Joni D.; Bissell, Mina J.; Barcellos-Hoff, Mary Helen

    2007-04-06

    Transforming growth factor {beta}1 (TGF{beta}) is a tumor suppressor during the initial stage of tumorigenesis, but it can switch to a tumor promoter during neoplastic progression. Ionizing radiation (IR), both a carcinogen and a therapeutic agent, induces TGF{beta}, activation in vivo. We now show that IR sensitizes human mammary epithelial cells (HMEC) to undergo TGF{beta}-mediated epithelial to mesenchymal transition (EMT). Non-malignant HMEC (MCF10A, HMT3522 S1 and 184v) were irradiated with 2 Gy shortly after attachment in monolayer culture, or treated with a low concentration of TGF{beta} (0.4 ng/ml), or double-treated. All double-treated (IR+TGF{beta}) HMEC underwent a morphological shift from cuboidal to spindle-shaped. This phenotype was accompanied by decreased expression of epithelial markers E-cadherin, {beta}-catenin and ZO-1, remodeling of the actin cytoskeleton, and increased expression of mesenchymal markers N-cadherin, fibronectin and vimentin. Furthermore, double-treatment increased cell motility, promoted invasion and disrupted acinar morphogenesis of cells subsequently plated in Matrigel{trademark}. Neither radiation nor TGF{beta} alone elicited EMT, even though IR increased chronic TGF{beta} signaling and activity. Gene expression profiling revealed that double treated cells exhibit a specific 10-gene signature associated with Erk/MAPK signaling. We hypothesized that IR-induced MAPK activation primes non-malignant HMEC to undergo TGF{beta}-mediated EMT. Consistent with this, Erk phosphorylation were transiently induced by irradiation, persisted in irradiated cells treated with TGF{beta}, and treatment with U0126, a Mek inhibitor, blocked the EMT phenotype. Together, these data demonstrate that the interactions between radiation-induced signaling pathways elicit heritable phenotypes that could contribute to neoplastic progression.

  1. The influence of pairing correlations on the isospin symmetry breaking corrections of superallowed Fermi beta decays

    SciTech Connect (OSTI)

    Cal Latin-Small-Letter-Dotless-I k, A. E.; Gerceklioglu, M.; Selam, C.

    2013-05-15

    Within the framework of quasi-particle random phase approximation, the isospin breaking correction of superallowed 0{sup +} {yields} 0{sup +} beta decay and unitarity of Cabibbo-Kobayashi-Maskawa mixing matrix have been investigated. The broken isotopic symmetry of nuclear part of Hamiltonian has been restored by Pyatov's method. The isospin symmetry breaking correction with pairing correlations has been compared with the previous results without pairing. The effect of pairing interactions has been examined for nine superallowed Fermi beta decays; their parent nuclei are {sup 26}Al, {sup 34}Cl, {sup 38}K, {sup 42}Sc, {sup 46}V, {sup 50}Mn, {sup 54}Co, {sup 62}Ga, {sup 74}Rb.

  2. Enhancement of [alpha]-Helix Mimicry by an [alpha/beta]-Peptide Foldamer

    Office of Scientific and Technical Information (OSTI)

    via Incorporation of a Dense Ionic Side-Chain Array (Journal Article) | SciTech Connect Enhancement of [alpha]-Helix Mimicry by an [alpha/beta]-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array Citation Details In-Document Search Title: Enhancement of [alpha]-Helix Mimicry by an [alpha/beta]-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array Authors: Johnson, Lisa M. ; Mortenson, David E. ; Yun, Hyun Gi ; Horne, W. Seth ; Ketas, Thomas J. ; Lu, Min ;

  3. First search for Lorentz and C P T violation in double beta decay with

    Office of Scientific and Technical Information (OSTI)

    EXO-200 (Journal Article) | SciTech Connect First search for Lorentz and C P T violation in double beta decay with EXO-200 Citation Details In-Document Search This content will become publicly available on April 1, 2017 Title: First search for Lorentz and C P T violation in double beta decay with EXO-200 Authors: Albert, J. B. ; Barbeau, P. S. ; Beck, D. ; Belov, V. ; Breidenbach, M. ; Brunner, T. ; Burenkov, A. ; Cao, G. F. ; Chambers, C. ; Cleveland, B. ; Coon, M. ; Craycraft, A. ;

  4. Status of the MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-Beta

    Office of Scientific and Technical Information (OSTI)

    Decay (Conference) | SciTech Connect Status of the MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-Beta Decay Citation Details In-Document Search Title: Status of the MAJORANA DEMONSTRATOR: A Search for Neutrinoless Double-Beta Decay × You are accessing a document from the Department of Energy's (DOE) SciTech Connect. This site is a product of DOE's Office of Scientific and Technical Information (OSTI) and is provided as a public service. Visit OSTI to utilize additional information

  5. Simulated annealing applied to two-dimensional low-beta reduced magnetohydrodynamics

    SciTech Connect (OSTI)

    Chikasue, Y.; Furukawa, M.

    2015-02-15

    The simulated annealing (SA) method is applied to two-dimensional (2D) low-beta reduced magnetohydrodynamics (R-MHD). We have successfully obtained stationary states of the system numerically by the SA method with Casimir invariants preserved. Since the 2D low-beta R-MHD has two fields, the relaxation process becomes complex compared to a single field system such as 2D Euler flow. The obtained stationary state can have fine structure. We have found that the fine structure appears because the relaxation processes are different between kinetic energy and magnetic energy.

  6. Low-energy beta spectroscopy using pin diodes to monitor tritium surface contamination

    SciTech Connect (OSTI)

    Wampler, W.R.; Doyle, B.L.

    1994-06-01

    We show that tritium betas emitted from a surface can be counted using a pin photodiode as a solid state charged particle detector. Furthermore, we show that the range of tritium betas through air is sufficient to allow measurement of tritium on samples in air by this method. These two findings make possible a new method to survey tritium surface contamination which has advantages over existing methods. We have built and tested several prototype instruments which use this method to measure tritium surface contamination, including a compact portable unit. The design of these instruments and results from tests and calibrations are described. Potential applications of this new method to monitor tritium are discussed.

  7. Low molecular weight thermostable {beta}-D-glucosidase from Acidothermus cellulolyticus

    DOE Patents [OSTI]

    Himmel, M.E.; Tucker, M.P.; Adney, W.S.; Nieves, R.A.

    1995-07-11

    A purified low molecular weight {beta}-D-glucosidase is produced from Acidothermus cellulolyticus ATCC 43068. The enzyme is water soluble, possesses activity against pNP-{beta}-D-glucopyranoside, has a high of degree of stability toward heat, exhibits optimal temperature activity at about 65 C at a pH range of from about 2 to about 7, has an inactivation temperature of about 80 C at a pH range of from about 2 to about 7 and has a molecular weight of about 50.5--54.5 kD as determined by SDS-PAGE. 6 figs.

  8. Low molecular weight thermostable .beta.-D-glucosidase from acidothermus cellulolyticus

    DOE Patents [OSTI]

    Himmel, Michael E.; Tucker, Melvin P.; Adney, William S.; Nieves, Rafael A.

    1995-01-01

    A purified low molecular weight .beta.-D-glucosidase is produced from Acidothermus cellulolyticus ATCC 43068. The enzyme is water soluble, possesses activity against pNP-.beta.-D-glucopyranoside, has a high of degree of stability toward heat, exhibits optimal temperature activity at about 65.degree. C. at a pH range of from about 2 to about 7, has an inactivation temperature of about 80.degree. C. at a pH range of from about 2 to about 7 and has a molecular weight of about 50.5-54.5 kD as determineded by SDS-PAGE.

  9. Optimization of the Transport Shield for Neutrinoless Double Beta-decay Enriched Germanium

    SciTech Connect (OSTI)

    Aguayo Navarrete, Estanislao; Kouzes, Richard T.; Orrell, John L.; Reid, Douglas J.; Fast, James E.

    2012-04-15

    This document presents results of an investigation of the material and geometry choice for the transport shield of germanium, the active detector material used in 76Ge neutrinoless double beta decay searches. The objective of this work is to select the optimal material and geometry to minimize cosmogenic production of radioactive isotopes in the germanium material. The design of such a shield is based on the calculation of the cosmogenic production rate of isotopes that are known to cause interfering backgrounds in 76Ge neutrinoless double beta decay searches.

  10. Discovery of Type II Inhibitors of TGF[beta]-Activated Kinase 1 (TAK1) and

    Office of Scientific and Technical Information (OSTI)

    Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (Journal Article) | SciTech Connect Discovery of Type II Inhibitors of TGF[beta]-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Citation Details In-Document Search Title: Discovery of Type II Inhibitors of TGF[beta]-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Authors: Tan, Li ; Nomanbhoy, Tyzoon ; Gurbani, Deepak ; Patricelli,

  11. The MAJORANA experiment: an ultra-low background search for neutrinoless double-beta decay

    SciTech Connect (OSTI)

    Phillips, D.; Aguayo Navarrete, Estanislao; Avignone, Frank T.; Back, Henning O.; Barabash, Alexander S.; Bergevin, M.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Collar, J. I.; Combs, Dustin C.; Cooper, R. J.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, Steven R.; Esterline, James H.; Fast, James E.; Fields, N.; Finnerty, P.; Fraenkle, Florian; Gehman, Victor; Giovanetti, G. K.; Green, Matthew P.; Guiseppe, Vincente; Gusey, K.; Hallin, A. L.; Hazama, R.; Henning, Reyco; Hime, Andrew; Hoppe, Eric W.; Horton, Mark; Howard, Stanley; Howe, M. A.; Johnson, R. A.; Keeter, K.; Keller, C.; Kidd, Mary; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; LaFerriere, Brian D.; LaRoque, B. H.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; MacMullin, S.; Marino, Michael G.; Martin, R. D.; Mei, Dong-Ming; Merriman, Jason H.; Miller, M. L.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; Overman, Nicole R.; Poon, Alan; Perumpilly, Gopakumar; Prior, Gersende; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Schubert, Alexis G.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Steele, David; Strain, J.; Thomas, K.; Timkin, V.; Tornow, W.; Vanyushin, I.; Varner, R. L.; Vetter, Kai; Vorren, Kris R.; Wilkerson, J. F.; Wolfe, B. A.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir; Zhang, C.

    2012-12-01

    The observation of neutrinoless double-beta decay would resolve the Majorana nature of the neutrino and could provide information on the absolute scale of the neutrino mass. The initial phase of the Majorana Experiment, known as the Demonstrator, will house 40 kg of Ge in an ultra-low background shielded environment at the 4850' level of the Sanford Underground Laboratory in Lead, SD. The objective of the Demonstrator is to validate whether a future 1-tonne experiment can achieve a background goal of one count per tonne-year in a narrow region of interest around the 76Ge neutrinoless double-beta decay peak.

  12. Search for Majoron-emitting modes of double-beta decay of Xe 136 with

    Office of Scientific and Technical Information (OSTI)

    EXO-200 (Journal Article) | SciTech Connect Search for Majoron-emitting modes of double-beta decay of Xe 136 with EXO-200 Citation Details In-Document Search Title: Search for Majoron-emitting modes of double-beta decay of Xe 136 with EXO-200 Authors: Albert, J. B. ; Auty, D. J. ; Barbeau, P. S. ; Beauchamp, E. ; Beck, D. ; Belov, V. ; Benitez-Medina, C. ; Breidenbach, M. ; Brunner, T. ; Burenkov, A. ; Cao, G. F. ; Chambers, C. ; Chaves, J. ; Cleveland, B. ; Coon, M. ; Craycraft, A. ;

  13. Relativistic QRPA Calculation of {beta}-Decay Rates of r-process Nuclei

    SciTech Connect (OSTI)

    Marketin, T.; Paar, N.; Niksic, T.; Vretenar, D.; Ring, P.

    2009-08-26

    A systematic, fully self-consistent calculation of {beta}-decay rates is presented, based on a microscopic theoretical framework. Analysis is performed on a large number of nuclei from the valley of {beta} stability towards the neutron drip-line. Nuclear ground state is determined using the Relativistic Hartree-Bogoliubov (RHB) model with density-dependent meson-nucleon coupling constants. Transition rates are calculated within the proton-neutron relativistic quasiparticle RPA (pn-RQRPA) using the same interaction that was used in the RHB equations.

  14. Measurement of the electron antineutrino mass from the beta spectrum of gaseous tritium

    SciTech Connect (OSTI)

    Knapp, D.A.

    1986-12-01

    A measurement has been made of the mass of the electron antineutrino using the beta spectrum from a source of gaseous molecular tritium, and an upper limit of 36 eV/c/sup 2/ has been set on this mass. This measurement is the first upper limit on neutrino mass that does not rely on assumptions about the atomic configuration after the beta decay, and it has significantly smaller systematic errors associated with it than do previous measurements. 130 refs., 83 figs., 8 tabs.

  15. Wnt Antagonists Bind through a Short Peptide to the First beta-Propeller

    Office of Scientific and Technical Information (OSTI)

    Domain of LRP5/6 (Journal Article) | SciTech Connect Wnt Antagonists Bind through a Short Peptide to the First beta-Propeller Domain of LRP5/6 Citation Details In-Document Search Title: Wnt Antagonists Bind through a Short Peptide to the First beta-Propeller Domain of LRP5/6 Authors: Bourhis, E. ; Wang, W. ; Tam, C. ; Hwang, J. ; Zhang, Y. ; Spittler, D. ; Huang, O.W. ; Gong, Y. ; Estevez, A. ; Zilberley, I. ; Rouge, L. ; Chiu, C. ; Wu, Y. ; Costa, M. ; Hannoush, R.N. ; Franke, Y. ; Cochran,

  16. Monthly Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Management Monthly Reports - FY 2014 The Department of Energy Nevada Field Office Environmental Management Program creates monthly reports for the NSSAB. These...

  17. Monthly Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Management Monthly Reports - FY 2015 The Department of Energy Nevada Field Office Environmental Management Program creates monthly reports for the NSSAB. These...

  18. Monthly Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Management Monthly Reports - FY 2013 The Department of Energy Nevada Field Office Environmental Management Program creates monthly reports for the NSSAB. These...

  19. Monthly Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Management Monthly Reports - FY 2012 The Department of Energy Nevada Field Office Environmental Management Program creates monthly reports for the NSSAB. These...

  20. Data Report

    Office of Legacy Management (LM)

    NDC 641 Results, Isotech Laboratories RESULTS REPORT RIN: 07081103 Site: Rulison Site Location: 35-12 Ticket Number: NDC 641 Report Date: 342008 Parameter Units Sample Date ID ...

  1. AUDIT REPORT

    Broader source: Energy.gov (indexed) [DOE]

    General SUBJECT: INFORMATION: Audit Report: "Security Improvements at the Y-12 ... In June 2004, the Office of Inspector General's report on Management of the Department's ...

  2. Reporting Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reporting Requirements Reporting Requirements Contacts Director Albert Migliori Deputy Franz Freibert 505 667-6879 Email Professional Staff Assistant Susan Ramsay 505 665 0858...

  3. Recent developments in the theory of double beta decay

    SciTech Connect (OSTI)

    Iachello, F.; Kotila, J.; Barea, J.

    2013-12-30

    We report results of a novel calculation of phase space factors for 2??{sup +}?{sup +}, 2??{sup +}EC, 2?ECEC, 0??{sup +}?{sup +}, and 0??{sup +}EC using exact Dirac wave functions, and finite nuclear size and electron screening corrections. We present results of expected half-lives for 0??{sup +}?{sup +} and 0??{sup +}EC decays obtained by combining the calculation of phase space factors with IBM-2 nuclear matrix elements.

  4. Measurement of the \\textit{CP} Violating Phase $\\boldsymbol{\\sin(2\\beta_{s})}$ using $\\boldsymbol{B^{0}_{s}\\rightarrow J/\\psi\\phi}$ Decays at CDF

    SciTech Connect (OSTI)

    Pueschel, Elisa; /Carnegie Mellon U.

    2010-05-01

    A B{sub s}{sup 0} meson can oscillate into its anti-particle, the {bar B}{sub s}{sup 0} meson, before decaying. CP violation in this system is made possible by the presence of amplitudes from both mixed and unmixed B{sub s}{sup 0} meson decays. The CP violating phase {beta}s appears in the interference between the decay amplitudes. The quantity sin(2{beta}s) is expected to be small in the standard model. Thus, measuring a large value for sin(2{beta}s) would be an unequivocal sign of new physics participation in the B{sub s}{sup 0} mixing loop diagram. In this thesis, we present a latest measurement of sin(2{beta}s), using 5.2 fb{sup -1} of data collected at CDF from p{bar p} collisions at a center of mass energy of {radical}s = 1.96 TeV. A time-dependent angular analysis, with the production flavor of the B{sub s}{sup 0} meson identified with flavor tagging methods, is used to extract sin(2{beta}s) from {approx}6500 B{sub s}{sup 0} {yields} J/{psi}{phi} decays. Other parameters of interest, such as the B{sub s}{sup 0} lifetime and the decay width difference {Delta}{Lambda} between the heavy and light B{sub s}{sup 0} mass eigenstates are determined to high precision. Also, the effect of potential contributions to the final state from B{sub s}{sup 0} {yields} J/{psi}f{sub 0} and B{sub s}{sup 0} {yields} J/{psi}K{sup +}K{sup -} decays is considered for the first time. We present 68% and 95% confidence regions in the {beta}s - {Delta}{Lambda} plane. The probability that the observed central value is a fluctuation of the data from the standard model expected value of {beta}s is calculated to be 44%. The observed confidence region shows better agreement with the standard model prediction than previous measurements.

  5. A measurement of the 2 neutrino double beta decay rate of Te-130 in the CUORICINO experiment

    SciTech Connect (OSTI)

    Kogler, Laura

    2011-11-03

    CUORICINO was a cryogenic bolometer experiment designed to search for neutrinoless double beta decay and other rare processes, including double beta decay with two neutrinos (2{nu}{beta}{beta}). The experiment was located at Laboratori Nazionali del Gran Sasso and ran for a period of about 5 years, from 2003 to 2008. The detector consisted of an array of 62 TeO{sub 2} crystals arranged in a tower and operated at a temperature of #24;10 mK. Events depositing energy in the detectors, such as radioactive decays or impinging particles, produced thermal pulses in the crystals which were read out using sensitive thermistors. The experiment included 4 enriched crystals, 2 enriched with {sup 130}Te and 2 with {sup 128}Te, in order to aid in the measurement of the 2{nu}{beta}{beta} rate. The enriched crystals contained a total of #24;350 g {sup 130}Te. The 128-enriched (130-depleted) crystals were used as background monitors, so that the shared backgrounds could be subtracted from the energy spectrum of the 130- enriched crystals. Residual backgrounds in the subtracted spectrum were fit using spectra generated by Monte-Carlo simulations of natural radioactive contaminants located in and on the crystals. The 2{nu}{beta}{beta} half-life was measured to be T{sup 2{nu}}{sub 1/2} = [9.81{+-} #6;0.96(stat){+-} 0.49(syst)]#2;x10{sup 20} y.

  6. Background Suppression Using Pulse Shape Analysis with a BEGe Detector for Neutrinoless Double Beta Decay Search with GERDA

    SciTech Connect (OSTI)

    Budjas, Dusan; Schoenert, Stefan [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Chkvorets, Oleg [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Department of Physics, Laurentian University, Ramsey Lake Road, P3E 2C6 Sudbury, Ontario (Canada)

    2009-12-17

    A pulse shape analysis for distinguishing between double beta decay-like interactions and multiple-scattered photons was performed for the first time using a BEGe-type detector. This discrimination method is included in the research and development for the second phase of the GERDA experiment, since active background suppression techniques are necessary to reach sensitivity for the {sup 76}Ge neutrinoless double beta decay half life of >10{sup 26} years. A suppression of backgrounds in the energy region of interest around the {sup 76}Ge Q{sub {beta}}{sub {beta}} = 2039 keV is demonstrated, with (0.93{+-}0.08)% survival probability for events from {sup 60}Co, (21{+-}3)% for {sup 226}Ra, and (40{+-}2)% for {sup 228}Th. This performance is achieved with (89{+-}1)% acceptance of {sup 228}Th double escape events, which are analogous to double beta decay.

  7. BGL3 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2012-10-30

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  8. Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production

    DOE Patents [OSTI]

    Jessen, Holly Jean; Liao, Hans H.; Gort, Steven John; Selifonova, Olga V.

    2011-10-04

    The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof.

  9. Nuclear structure relevant to neutrinoless double beta decay candidate {sup 130}Te and other recent results

    SciTech Connect (OSTI)

    Kay, B. P. [Physics Division, Argonne National Laboratory, Illinois 60439 (United States)

    2013-12-30

    We have undertaken a series of single-nucleon and pair transfer reaction measurements to help constrain calculations of the nuclear matrix elements for neutrinoless double beta decay. In this talk, a short overview of measurements relevant to the {sup 130}Te?{sup 130}Xe system is given. Brief mention is made of other recent and forthcoming results.

  10. Alpha Backgrounds for HPGe Detectors in Neutrinoless Double-Beta Decay Experiments

    SciTech Connect (OSTI)

    Johnson, R. A. [University of Washington, Seattle; Burritt, T. H. [University of Washington, Seattle; Elliott, S. R. [Los Alamos National Laboratory (LANL); Gehman, V. M. [Los Alamos National Laboratory (LANL); Guiseppe, V.E. [University of South Dakota; Wilkerson, J. F. [UNC/Triangle Univ. Nucl. Lab, Durham, NC/ORNL

    2012-01-01

    The Majorana Experiment will use arrays of enriched HPGe detectors to search for the neutrinoless double-beta decay of 76Ge. Such a decay, if found, would show lepton-number violation and confirm the Majorana nature of the neutrino. Searches for such rare events are hindered by obscuring backgrounds which must be understood and mitigated as much as possible. A potentially important background contribution to this and other double-beta decay experiments could come from decays of alpha-emitting isotopes in the 232Th and 238U decay chains on or near the surfaces of the detectors. An alpha particle emitted external to an HPGe crystal can lose energy before entering the active region of the detector, either in some external-bulk material or within the dead region of the crystal. The measured energy of the event will only correspond to a partial amount of the total kinetic energy of the alpha and might obscure the signal from neutrinoless double-beta decay. A test stand was built and measurements were performed to quantitatively assess this background. We present results from these measurements and compare them to simulations using Geant4. These results are then used to measure the alpha backgrounds in an underground detector in situ. We also make estimates of surface contamination tolerances for double-beta decay experiments using solid-state detectors.

  11. Neutrino decay and neutrinoless double beta decay in a 3-3-1 model

    SciTech Connect (OSTI)

    Dias, Alex G. [Instituto de Fisica, Universidade de Sao Paulo, Caixa Postal 66.318, 05315-970, Sao Paulo-SP (Brazil); Doff, A. [Instituto de Fisica Teorica, Universidade Estadual Paulista, Rua Pamplona 145, 01405-900 Sao Paulo-SP (Brazil); Pires, C.A. de S; Rodrigues da Silva, P.S. [Departamento de Fisica, Universidade Federal da Paraiba, Caixa Postal 5008, 58051-970, Joao Pessoa-PB (Brazil)

    2005-08-01

    In this work we show that the implementation of spontaneous breaking of the lepton number in the 3-3-1 model with right-handed neutrinos gives rise to fast neutrino decay with Majoron emission and generates a bunch of new contributions to the neutrinoless double beta decay.

  12. BGL7 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2013-01-29

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same.

  13. BGL6 .beta.-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2012-10-02

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same.

  14. BGL4 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2011-12-06

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL4, recombinant BGL4 proteins and methods for producing the same.

  15. BGL7 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2015-04-14

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same.

  16. BGL6 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2015-08-11

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same.

  17. BGL7 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2014-03-25

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same.

  18. BGL6 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2014-03-04

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same.

  19. BGL3 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2008-04-01

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  20. Evolution of a genetic disease in an ethnic isolate:. beta. -Thalassemia in the Jews of Kurdistan

    SciTech Connect (OSTI)

    Rund, D.; Cohen, T.; Filon, D.; Rachmilewitz, E.; Oppenheim, A. ); Dowling, C.E.; Warren T.C.; Kazazian, H.H. Jr. ); Barak, I. )

    1991-01-01

    {beta}-Thalassemia is a hereditary disease caused by any of 90 different point mutations in the {beta}-globin gene. Specific populations generally carry a small number of mutations, the most common of which are those that are widely distributed regionally. The present study constitutes an extensive molecular characterization of this disease in a small, highly inbred ethnic group with a high incidence of {beta}-thalassemia-the Jews of Kurdistan. An unusual mutational diversity was observed. In 42 sibships 13 different mutations were identified, of which 3 are newly discovered. Four of the mutations are unique to Kurdish Jews and have not been discovered in any other population. A fifth was found outside Kurdish Jews only in an Iranian from Khuzistan, a region bordering Kurdistan. Two-thirds of the mutant chromosomes carry the mutations unique to Kurdish Jews. The authors traced the origin of the mutations to specific geographic regions within Kurdistan. This information, supported by haplotype analysis, suggests that thalassemia in central Kurdistan (northern Iraq) has evolved primarily from multiple mutational events. They conclude that several evolutionary mechanisms contributed to the evolution of {beta}-thalassemia in this small ethnic isolate.

  1. BGL5 .beta.-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2008-03-18

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant BGL5 proteins and methods for producing the same.

  2. BGL3 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2007-09-25

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  3. BGL7 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2008-08-05

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same.

  4. BGL6 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Ward, Michael

    2009-09-01

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same.

  5. BGL4 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel [Los Gatos, CA; Goedegebuur, Frits [Vlaardingen, NL; Ward, Michael [San Francisco, CA; Yao, Jian [Sunnyvale, CA

    2008-01-22

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL4, recombinant BGL4 proteins and methods for producing the same.

  6. BGL3 beta-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2011-06-14

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  7. Method of forming single crystals of beta silicon carbide using liquid lithium as a solvent

    DOE Patents [OSTI]

    Lundberg, Lynn B.

    1982-01-01

    A method of growing single crystals of beta SiC from solution using molten lithium as a solvent for polycrystalline SiC feed material. Reasonable growth rates are accomplished at temperatures in the range of about 1330.degree. C. to about 1500.degree. C.

  8. Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production

    DOE Patents [OSTI]

    Jessen, Holly Jean; Liao, Hans H; Gort, Steven John; Selifonova, Olga V

    2014-11-18

    The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof.

  9. BGL5 .beta.-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2006-02-28

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant BGL5 proteins and methods for producing the same.

  10. BGL4 .beta.-glucosidase and nucleic acids encoding the same

    DOE Patents [OSTI]

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2006-05-16

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL4, recombinant BGL4 proteins and methods for producing the same.

  11. Polypeptides having beta-glucosidase activity and polynucleotides encoding the same

    DOE Patents [OSTI]

    Brown, Kimberly; Harris, Paul

    2013-12-17

    The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  12. Oracle Applications Patch Administration Tool (PAT) Beta Version

    Energy Science and Technology Software Center (OSTI)

    2002-01-04

    PAT is a Patch Administration Tool that provides analysis, tracking, and management of Oracle Application patches. This includes capabilities as outlined below: Patch Analysis & Management Tool Outline of capabilities: Administration Patch Data Maintenance -- track Oracle Application patches applied to what database instance & machine Patch Analysis capture text files (readme.txt and driver files) form comparison detail report comparison detail PL/SQL package comparison detail SQL scripts detail JSP module comparison detail Parse and loadmore » the current applptch.txt (10.7) or load patch data from Oracle Application database patch tables (11i) Display Analysis -- Compare patch to be applied with current Oracle Application installed Appl_top code versions Patch Detail Module comparison detail Analyze and display one Oracle Application module patch. Patch Management -- automatic queue and execution of patches Administration Parameter maintenance -- setting for directory structure of Oracle Application appl_top Validation data maintenance -- machine names and instances to patch Operation Patch Data Maintenance Schedule a patch (queue for later execution) Run a patch (queue for immediate execution) Review the patch logs Patch Management Reports« less

  13. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SANDIA REPORT SAND2014-4753 Unlimited Release Printed December 2014 Analysis of 100 SGIP ... NOTICE: This report was prepared as an account of work sponsored by an agency of the ...

  14. Data Report

    Office of Legacy Management (LM)

    NDC 644 Results, Paragon Analytics RESULTS REPORT RIN: 07081112 Site: Rulison Site Location: 35-32A Ticket Number: NDC 644 Report Date: 342008 Parameter Units Sample Date ID ...

  15. Annual Report

    Energy Savers [EERE]

    Information Act report covers the Period 10012009, through 09302010, as required by 5 U.S.C. 552. I. BASIC INFORMATION REGARDING REPORT 1. Kevin T. Hagerty, Director Office...

  16. Tumor suppressor KAI1 affects integrin {alpha}v{beta}3-mediated ovarian cancer cell adhesion, motility, and proliferation

    SciTech Connect (OSTI)

    Ruseva, Zlatna; Geiger, Pamina Xenia Charlotte; Hutzler, Peter; Kotzsch, Matthias; Luber, Birgit; Schmitt, Manfred; Gross, Eva; Reuning, Ute

    2009-06-10

    The tetraspanin KAI1 had been described as a metastasis suppressor in many different cancer types, a function for which associations of KAI1 with adhesion and signaling receptors of the integrin superfamily likely play a role. In ovarian cancer, integrin {alpha}v{beta}3 correlates with tumor progression and its elevation in vitro provoked enhanced cell adhesion accompanied by significant increases in cell motility and proliferation in the presence of its major ligand vitronectin. In the present study, we characterized integrin {alpha}v{beta}3-mediated tumor biological effects as a function of cellular KAI1 restoration and proved for the first time that KAI1, besides its already known physical crosstalk with {beta}1-integrins, also colocalizes with integrin {alpha}v{beta}3. Functionally, elevated KAI1 levels drastically increased integrin {alpha}v{beta}3/vitronectin-dependent ovarian cancer cell adhesion. Since an intermediate level of cell adhesive strength is required for optimal cell migration, we next studied ovarian cancer cell motility as a function of KAI1 restoration. By time lapse video microscopy, we found impaired integrin {alpha}v{beta}3/vitronectin-mediated cell migration most probably due to strongly enhanced cellular immobilization onto the adhesion-supporting matrix. Moreover, KAI1 reexpression significantly diminished cell proliferation. These data strongly indicate that KAI1 may suppress ovarian cancer progression by inhibiting integrin {alpha}v{beta}3/vitronectin-provoked tumor cell motility and proliferation as important hallmarks of the oncogenic process.

  17. Liquid-Metal Electrode to Enable Ultra-Low Temperature Sodium-Beta Alumina Batteries for Renewable Energy Storage

    SciTech Connect (OSTI)

    Lu, Xiaochuan; Li, Guosheng; Kim, Jin Yong; Mei, Donghai; Lemmon, John P.; Sprenkle, Vincent L.; Liu, Jun

    2014-08-01

    Metal electrodes have a high capacity for energy storage but have found limited applications in batteries because of dendrite formation and other problems. In this paper, we report a new alloying strategy that can significantly reduce the melting temperature and improve wetting with the electrolyte to allow the use of liquid metal as anode in sodium-beta alumina batteries (NBBs) at much lower temperatures (e.g., 95 to 175°C). Commercial NBBs such as sodium-sulfur (Na-S) battery and sodium-metal halide (ZEBRA) batteries typically operate at relatively high temperatures (e.g., 300-350°C) due to poor wettability of sodium on the surface of β"-Al2O3. Our combined experimental and computational studies suggest that Na-Cs alloy can replace pure sodium as the anode material, which provides a significant improvement in wettability, particularly at lower temperatures (i.e., <200°C). Single cells with the Na-Cs alloy anode exhibit excellent cycling life over those with pure sodium anode at 175 and 150°C. The cells can even operate at 95°C, which is below the melting temperature of pure sodium. These results demonstrate that NBB can be operated at ultra lower temperatures with successfully solving the wetting issue. This work also suggests a new strategy to use liquid metal as the electrode materials for advanced batteries that can avoid the intrinsic safety issues associated with dendrite formation on the anode.

  18. MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts

    SciTech Connect (OSTI)

    Li, Xiaoou; Liu, Lian; Shen, Yongchun; Wang, Tao; Chen, Lei; Xu, Dan; Wen, Fuqiang

    2014-11-28

    Highlights: • Endogenous miR-26a inhibits TGF-beta 1 induced proliferation of lung fibroblasts. • miR-26a induces G1 arrest through directly targeting 3′-UTR of CCND2. • TGF indispensable receptor, TGF-beta R I, is regulated by miR-26a. • miR-26a acts through inhibiting TGF-beta 2 feedback loop to reduce TGF-beta 1. • Collagen type I and connective tissue growth factor are suppressed by miR-26a. - Abstract: MicroRNA-26a is a newly discovered microRNA that has a strong anti-tumorigenic capacity and is capable of suppressing cell proliferation and activating tumor-specific apoptosis. However, whether miR-26a can inhibit the over-growth of lung fibroblasts remains unclear. The relationship between miR-26a and lung fibrosis was explored in the current study. We first investigated the effect of miR-26a on the proliferative activity of human lung fibroblasts with or without TGF-beta1 treatment. We found that the inhibition of endogenous miR-26a promoted proliferation and restoration of mature miR-26a inhibited the proliferation of human lung fibroblasts. We also examined that miR-26a can block the G1/S phase transition via directly targeting 3′-UTR of CCND2, degrading mRNA and decreasing protein expression of Cyclin D2. Furthermore, we showed that miR-26a mediated a TGF-beta 2-TGF-beta 1 feedback loop and inhibited TGF-beta R I activation. In addition, the overexpression of miR-26a also significantly suppressed the TGF-beta 1-interacting-CTGF–collagen fibrotic pathway. In summary, our studies indicated an essential role of miR-26a in the anti-fibrotic mechanism in TGF-beta1-induced proliferation in human lung fibroblasts, by directly targeting Cyclin D2, regulating TGF-beta R I as well as TGF-beta 2, and suggested the therapeutic potential of miR-26a in ameliorating lung fibrosis.

  19. Princeton Plasma Physics Laboratory: Annual report, October 1, 1986--September 30, 1987

    SciTech Connect (OSTI)

    Not Available

    1987-01-01

    This report contains papers on the following topics: Principle Parameters Achieved in Experimental Devices (FY87); Tokamak Fusion Test Reactor; Princeton Beta Experiment-Modification; S-1 Spheromak; Current-Drive Experiment; X-Ray Laser Studies; Theoretical Division; Tokamak Modeling; Compact Ignition Tokamak; Engineering Department; Project Planning and Safety Office; Quality Assurance and Reliability; Administrative Operations; and PPPL Patent Invention Disclosures (FY87).

  20. Connecting the X(5)-{beta}{sup 2}, X(5)-{beta}{sup 4}, and X(3) models to the shape/phase-transition region of the interacting boson model

    SciTech Connect (OSTI)

    McCutchan, E. A.; Bonatsos, Dennis; Zamfir, N. V.

    2006-09-15

    The parameter independent (up to overall scale factors) predictions of the X(5)-{beta}{sup 2}, X(5)-{beta}{sup 4}, and X(3) models, which are variants of the X(5) critical point symmetry developed within the framework of the geometric collective model, are compared to two-parameter calculations in the framework of the interacting boson approximation (IBA) model. The results show that these geometric models coincide with IBA parameters consistent with the shape/phase-transition region of the IBA for boson numbers of physical interest (close to 10). Nuclei within the rare-earth region and select Os and Pt isotopes are identified as good examples of X(3), X(5)-{beta}{sup 2}, and X(5)-{beta}{sup 4} behavior.

  1. Connecting the X(5)-{beta}{sup 2}, X(5)-{beta}{sup 4}, and X(3) models to the shape/phase transition region of the interacting boson model

    SciTech Connect (OSTI)

    McCutchan, E. A. Bonatsos, D. Zamfir, N. V.

    2007-08-15

    The parameter-independent (up to overall scale factors) predictions of the X(5)-{beta}{sup 2},X(5)-{beta}{sup 4}, and X(3) models, which are variants of the X(5) critical point symmetry developed within the framework of the geometric collective model, are compared to two-parameter calculations in the framework of the interacting boson approximation (IBA) model. The results show that these geometric models coincide with IBA parameters consistent with the phase/shape transition region of the IBA for boson numbers of physical interest (close to 10). {sup 186}Pt and {sup 172}Os are identified as good examples of X(3), while {sup 146}Ce, {sup 174}Os, and {sup 158}Er, {sup 176}Os are identified as good examples of X(5)-{beta}{sub 2} and X(5)-{beta}{sup 4} behavior, respectively.

  2. Neutrinoless double-{beta} decay of {sup 150}Nd accounting for deformation

    SciTech Connect (OSTI)

    Fang Dongliang; Faessler, Amand; Rodin, Vadim; Simkovic, Fedor [Institut fuer Theoretische Physik, Universitaet Tuebingen, D-72076 Tuebingen (Germany); BLTP, JINR, Dubna (Russian Federation) and Department of Nuclear Physics, Comenius University, SK-842 15 Bratislava (Slovakia)

    2010-11-15

    A microscopic state-of-the-art calculation of the nuclear matrix element for neutrinoless double-{beta} decay of {sup 150}Nd with an account for nuclear deformation is performed. The proton-neutron quasiparticle random phase approximation (QRPA) with a realistic residual interaction [the Brueckner G matrix derived from the charge-dependent Bonn (Bonn-CD) nucleon-nucleon potential] is used as the underlying nuclear structure model. The present calculated matrix element is suppressed by about 40% as compared with our previous QRPA result for {sup 150}Nd obtained with neglect of deformation. By making use of this newest nuclear matrix element, one may conclude that neutrinoless double-{beta} decay of {sup 150}Nd, to be measured soon by the SNO+ collaboration, provides one of the best probes of the Majorana neutrino mass.

  3. Pion dominance in R-parity violating supersymmetry induced neutrinoless double beta decay

    SciTech Connect (OSTI)

    Faessler, Amand; Gutsche, Thomas; Simkovic, Fedor [Institute fuer Theoretische Physik der Universitaet Tuebingen, D-72076 Tuebingen (Germany); Kovalenko, Sergey [Centro de Estudios Subatomicos (CES), Universidad Tecnica Federico Santa Maria, Casilla 110-V, Valparaiso (Chile)

    2008-06-01

    At the quark level there are basically two types of contributions of R-parity violating supersymmetry (Re{sub p} SUSY) to neutrinoless double beta decay: the short-range contribution involving only heavy virtual superpartners and the long-range one with the virtual squark and neutrino. Hadronization of the effective operators, corresponding to these two types of contributions, may in general involve virtual pions in addition to close on-mass-shell nucleons. From the previous studies it is known that the short-range contribution is dominated by the pion exchange. In the present paper we show that this is also true for the long-range Re{sub p} SUSY contribution. Therefore, we conclude that the Re{sub p} SUSY contributes to the neutrinoless double beta decay dominantly via charged pion exchange between the decaying nucleons.

  4. .beta.-silicon carbide protective coating and method for fabricating same

    DOE Patents [OSTI]

    Carey, Paul G.; Thompson, Jesse B.

    1994-01-01

    A polycrystalline beta-silicon carbide film or coating and method for forming same on components, such as the top of solar cells, to act as an extremely hard protective surface, and as an anti-reflective coating. This is achieved by DC magnetron co-sputtering of amorphous silicon and carbon to form a SiC thin film onto a surface, such as a solar cell. The thin film is then irradiated by a pulsed energy source, such as an excimer laser, to synthesize the poly- or .mu.c-SiC film on the surface and produce .beta.--SiC. While the method of this invention has primary application in solar cell manufacturing, it has application wherever there is a requirement for an extremely hard surface.

  5. [beta]-silicon carbide protective coating and method for fabricating same

    DOE Patents [OSTI]

    Carey, P.G.; Thompson, J.B.

    1994-11-01

    A polycrystalline beta-silicon carbide film or coating and method for forming same on components, such as the top of solar cells, to act as an extremely hard protective surface, and as an anti-reflective coating are disclosed. This is achieved by DC magnetron co-sputtering of amorphous silicon and carbon to form a SiC thin film onto a surface, such as a solar cell. The thin film is then irradiated by a pulsed energy source, such as an excimer laser, to synthesize the poly- or [mu]c-SiC film on the surface and produce [beta]-SiC. While the method of this invention has primary application in solar cell manufacturing, it has application wherever there is a requirement for an extremely hard surface. 3 figs.

  6. Beta Test Plan for Advanced Inverters Interconnecting Distributed Resources with Electric Power Systems

    SciTech Connect (OSTI)

    Hoke, A.; Chakraborty, S.; Basso, T.; Coddington, M.

    2014-01-01

    This document provides a preliminary (beta) test plan for grid interconnection systems of advanced inverter-based DERs. It follows the format and methodology/approach established by IEEE Std 1547.1, while incorporating: 1. Upgraded tests for responses to abnormal voltage and frequency, and also including ride-through. 2. A newly developed test for voltage regulation, including dynamic response testing. 3. Modified tests for unintentional islanding, open phase, and harmonics to include testing with the advanced voltage and frequency response functions enabled. Two advanced inverters, one single-phase and one three-phase, were tested under the beta test plan. These tests confirmed the importance of including tests for inverter dynamic response, which varies widely from one inverter to the next.

  7. Shape coexistence in {sup 180}Hg studied through the {beta} decay of {sup 180}Tl

    SciTech Connect (OSTI)

    Elseviers, J.; Bree, N.; Diriken, J.; Huyse, M.; Ivanov, O.; Van den Bergh, P.; Van Duppen, P.; Andreyev, A. N.; Antalic, S.; Barzakh, A.; Fedorov, D.; Cocolios, T. E.; Seliverstov, M.; Comas, V. F.; Heredia, J. A.; Fedosseyev, V. N.; Marsh, B. A.; Franchoo, S.; Page, R. D.

    2011-09-15

    The {beta}{sup +}/EC decay of {sup 180}Tl and excited states in the daughter nucleus {sup 180}Hg have been investigated at the CERN On-Line Isotope Mass Separator (ISOLDE) facility. Many new low-lying energy levels were observed in {sup 180}Hg, of which the most significant are the 0{sub 2}{sup +} at 419.6 keV and the 2{sub 2}{sup +} at 601.3 keV. The former is the bandhead of an excited band in {sup 180}Hg assumed originally to be of prolate nature. From the {beta} feeding to the different states in {sup 180}Hg, the ground-state spin of {sup 180}Tl was deduced to be (4{sup -},5{sup -}).

  8. Building Restoration Operations Optimization Model Beta Version 1.0

    Energy Science and Technology Software Center (OSTI)

    2007-05-31

    The Building Restoration Operations Optimization Model (BROOM), developed by Sandia National Laboratories, is a software product designed to aid in the restoration of large facilities contaminated by a biological material. BROOM’s integrated data collection, data management, and visualization software improves the efficiency of cleanup operations, minimizes facility downtime, and provides a transparent basis for reopening the facility. Secure remote access to building floor plans Floor plan drawings and knowledge of the HVAC system are criticalmore » to the design and implementation of effective sampling plans. In large facilities, access to these data may be complicated by the sheer abundance and disorganized state they are often stored in. BROOM avoids potentially costly delays by providing a means of organizing and storing mechanical and floor plan drawings in a secure remote database that is easily accessed. Sampling design tools BROOM provides an array of tools to answer the question of where to sample and how many samples to take. In addition to simple judgmental and random sampling plans, the software includes two sophisticated methods of adaptively developing a sampling strategy. Both tools strive to choose sampling locations that best satisfy a specified objective (i.e. minimizing kriging variance) but use numerically different strategies to do so. Surface samples are collected early in the restoration process to characterize the extent of contamination and then again later to verify that the facility is safe to reenter. BROOM supports sample collection using a ruggedized PDA equipped with a barcode scanner and laser range finder. The PDA displays building floor drawings, sampling plans, and electronic forms for data entry. Barcodes are placed on sample containers for the purpose of tracking the specimen and linking acquisition data (i.e. location, surface type, texture) to laboratory results. Sample location is determined by activating the integrated laser range finder which uses the PDA drawings to accurately measure position relative to nearby walls or other interior structures. The PDA and desktop application exchange information over a secure wireless network, Through this network, the progress of sampling activities may be monitored in real-time. PDA-acquired data is ultimately transferred over the network to the desktop where it is stored permanently in the project database. Once in the database, the data may be viewed, analyzed, or reported from the desktop. Mapping A picture is worth a thousand words. BROOM includes both inverse distance and kriging interpolation algorithms which are used to generate continuous contamination maps and display underlying confidence. Such maps greatly assist in interpreting discrete sample data and communicating results to others. Data Management The BROOM database provides a streamlined means of storing. retrieving, viewing, and analyzing the various data associated with recovery operations. Critical floor plan drawings and other pertinent images may be organized and stored in the database before an event occurs. History indicates that thousands of samples will need to be collected and analyzed by contractors, laboratories, government agencies. and other stakeholders. The BROOM database provides a secure, easy to use plafform, where these data may be centrally stored and shared among all concerned parties.« less

  9. DOE Science Showcase - Neutrinoless Double Beta Decay | OSTI, US Dept of

    Office of Scientific and Technical Information (OSTI)

    Energy, Office of Scientific and Technical Information Neutrinoless Double Beta Decay "Ultra High Purity Electro-Formed Copper" Image Credit: PNNL. Neutrinos are created as a result of certain types of radioactive decay, or nuclear reactions such as those that take place in the Sun, in nuclear reactors, or when cosmic rays hit atoms. These particles are known to exist in three states: as electron neutrinos, muon neutrinos, and tau neutrinos. The neutrino is associated with an

  10. Probing new physics in the neutrinoless double beta decay using electron angular correlation

    SciTech Connect (OSTI)

    Ali, A.; Borisov, A. V.; Zhuridov, D. V. [Deutsches Elektronen-Synchrotron, DESY, 22607 Hamburg (Germany); Faculty of Physics, Moscow State University, 119991 Moscow (Russian Federation)

    2007-11-01

    The angular correlation of the electrons emitted in the neutrinoless double beta decay (0{nu}2{beta}) is presented using a general Lorentz invariant effective Lagrangian for the leptonic and hadronic charged weak currents. We show that the coefficient K in the angular correlation d{gamma}/dcos{theta}{proportional_to}(1-Kcos{theta}) is essentially independent of the nuclear matrix element models and present its numerical values for the five nuclei of interest ({sup 76}Ge, {sup 82}Se, {sup 100}Mo, {sup 130}Te, and {sup 136}Xe), assuming that the 0{nu}2{beta} decays in these nuclei are induced solely by a light Majorana neutrino, {nu}{sub M}. This coefficient varies between K=0.81 (for the {sup 76}Ge nucleus) and K=0.88 (for the {sup 82}Se and {sup 100}Mo nuclei), calculated taking into account the effects from the nucleon recoil, the S and P waves for the outgoing electrons and the electron mass. Deviation of K from its values derived here would indicate the presence of new physics (NP) in addition to a light Majorana neutrino, and we work out the angular coefficients in several {nu}{sub M}+NP scenarios for the {sup 76}Ge nucleus. As an illustration of the correlations among the 0{nu}2{beta} observables (half-life T{sub 1/2}, the coefficient K, and the effective Majorana neutrino mass ||) and the parameters of the underlying NP model, we analyze the left-right symmetric models, taking into account current phenomenological bounds on the right-handed W{sub R}-boson mass and the left-right mixing parameter {zeta}.

  11. Left-Right Symmetry: From the LHC to Neutrinoless Double Beta Decay

    SciTech Connect (OSTI)

    Tello, Vladimir [SISSA, Trieste (Italy); Nemevsek, Miha [ICTP, Trieste (Italy); Jozef Stefan Institute, Ljubljana (Slovenia); Nesti, Fabrizio [Universita di Ferrara, Ferrara (Italy); Senjanovic, Goran [ICTP, Trieste (Italy); Vissani, Francesco [LNGS, INFN, Assergi (Italy)

    2011-04-15

    The Large Hadron Collider has the potential to probe the scale of left-right symmetry restoration and the associated lepton number violation. Moreover, it offers the hope of measuring the right-handed leptonic mixing matrix. We show how this, together with constraints from lepton flavor violating processes, can be used to make predictions for neutrinoless double beta decay. We illustrate this connection in the case of the type-II seesaw.

  12. Eia.gov BETA - U.S. Energy Information Administration (EIA) - U.S. Energy

    U.S. Energy Information Administration (EIA) Indexed Site

    Information Administration (EIA) Projects published on Beta are not final and may contain programming errors. They are for public testing and comment only. We welcome your feedback. For final products, please visit www.eia.gov. Read our feedback policy. Project Feedback Rea Give Us Your Feedback We welcome your feedback and insights on this project. Your Country: United States Afghanistan Albania Algeria American Samoa Angola Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia

  13. Synaptic Arrangement of the Neuroligin/beta-Neurexin Complex Revealed by

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    X-ray and Neutron Scattering Synaptic Arrangement of the Neuroligin/beta-Neurexin Complex Revealed by X-ray and Neutron Scattering Autism spectrum disorders are among the most devastating disorders of early childhood in terms of prevalence, family impact, and cost to society. Several mutations of the coding regions of the neuroligins and neurexins have been implicated through genetic screens in the pathogenesis of autism and mental retardation (Jamain et al., 2003; Laumonnier et al., 2004;

  14. GEN IV MATERIALS HANDBOOK BETA RELEASE FOR STRUCTURAL AND FUNCTIONAL EVALUATION

    SciTech Connect (OSTI)

    Ren, Weiju; Luttrell, Claire

    2006-09-12

    Development of the Gen IV Materials Handbook is briefly summarized up to date. Current status of the Handbook website construction is described. The developed Handbook components and access control of the beta version are discussed for the present evaluation release. Detailed instructions and examples are given to provide guidance for evaluators to browse the constructed parts and use all the currently developed functionalities of the Handbook in evaluation.

  15. Incomplete Laplace integrals - uniform asymptotic expansion with application to the incomplete beta function

    SciTech Connect (OSTI)

    Temme, N.M.

    1987-11-01

    The analytical approach of Temme (1983 and 1985), based on uniform asymptotic expansions, is extended to an additional class of incomplete Laplace integrals. The terminology is introduced; the construction of the formal series is explained; representations for the remainders are derived; the asymptotic nature of the expansions is explored; and error bounds are determined. Numerical results are presented for the case of the incomplete beta function. 14 references.

  16. A PARALLEL-PROPAGATING ALFVENIC ION-BEAM INSTABILITY IN THE HIGH-BETA SOLAR WIND

    SciTech Connect (OSTI)

    Verscharen, Daniel; Bourouaine, Sofiane; Chandran, Benjamin D. G.; Maruca, Bennett A. E-mail: s.bourouaine@unh.edu E-mail: bmaruca@ssl.berkeley.edu

    2013-08-10

    We investigate the conditions under which parallel-propagating Alfven/ion-cyclotron waves are driven unstable by an isotropic (T{sub {alpha}} = T{sub Parallel-To {alpha}}) population of alpha particles drifting parallel to the magnetic field at an average speed U{sub {alpha}} with respect to the protons. We derive an approximate analytic condition for the minimum value of U{sub {alpha}} needed to excite this instability and refine this result using numerical solutions to the hot-plasma dispersion relation. When the alpha-particle number density is {approx_equal} 5% of the proton number density and the two species have similar thermal speeds, the instability requires that {beta}{sub p} {approx}> 1, where {beta}{sub p} is the ratio of the proton pressure to the magnetic pressure. For 1 {approx}< {beta}{sub p} {approx}< 12, the minimum U{sub {alpha}} needed to excite this instability ranges from 0.7v{sub A} to 0.9v{sub A}, where v{sub A} is the Alfven speed. This threshold is smaller than the threshold of {approx_equal} 1.2v{sub A} for the parallel magnetosonic instability, which was previously thought to have the lowest threshold of the alpha-particle beam instabilities at {beta}{sub p} {approx}> 0.5. We discuss the role of the parallel Alfvenic drift instability for the evolution of the alpha-particle drift speed in the solar wind. We also analyze measurements from the Wind spacecraft's Faraday cups and show that the U{sub {alpha}} values measured in solar-wind streams with T{sub {alpha}} Almost-Equal-To T{sub Parallel-To {alpha}} are approximately bounded from above by the threshold of the parallel Alfvenic instability.

  17. IH&R DEPARTMENT MONTHLY REPORT FOR JULY & AUGUST 1979 R. C. Heatherton

    Office of Legacy Management (LM)

    313367 September 11, 1979 IH&R DEPARTMENT MONTHLY REPORT FOR JULY & AUGUST 1979 R. C. Heatherton M. W. Boback Environmental Monitoring - Monthly averages for uranium, alpha and beta radioactivity, and particulates were all within normal ranges. Period lo-l4 ).Ici/mb? us/m3 uraaim ,& - Beta Particulatee June 0.24 0.23 2.11 51 JdY 0.10 0.10 1.36 43 aueust 0.09 0.10 1.40 47 NCG 200 200 100,000 60 BreathingAir Quality - Tests of plant air and the Fire & Safety air compressor showed

  18. Inverse neutrinoless double beta decay revisited: Neutrinos, Higgs triplets, and a muon collider

    SciTech Connect (OSTI)

    Rodejohann, Werner [Max-Planck-Institut fuer Kernphysik, Postfach 103980, D-69029 Heidelberg (Germany)

    2010-06-01

    We revisit the process of inverse neutrinoless double beta decay (e{sup -}e{sup -{yields}}W{sup -}W{sup -}) at future linear colliders. The cases of Majorana neutrino and Higgs triplet exchange are considered. We also discuss the processes e{sup -{mu}-{yields}}W{sup -}W{sup -} and {mu}{sup -{mu}-{yields}}W{sup -}W{sup -}, which are motivated by the possibility of muon colliders. For heavy neutrino exchange, we show that masses up to 10{sup 6} (10{sup 5}) GeV could be probed for ee and e{mu} machines, respectively. The stringent limits for mixing of heavy neutrinos with muons render {mu}{sup -{mu}-{yields}}W{sup -}W{sup -} less promising, even though this process is not constrained by limits from neutrinoless double beta decay. If Higgs triplets are responsible for inverse neutrinoless double beta decay, observable signals are only possible if a very narrow resonance is met. We also consider unitarity aspects of the process in case both Higgs triplets and neutrinos are exchanged. An exact seesaw relation connecting low energy data with heavy neutrino and triplet parameters is found.

  19. Effect of quark sector minimal flavor violation on neutrinoless double beta decay

    SciTech Connect (OSTI)

    Dudley, Brian; Kolda, Christopher [Department of Physics, University of Notre Dame, Notre Dame, Indiana 46556 (United States)

    2009-01-01

    The question of whether neutrino masses are Dirac or Majorana is one of the most important, and most difficult, questions remaining in the neutrino sector. Searches for neutrinoless double {beta} decay may help to resolve this question, but are also sensitive to new, higher-dimension {delta}L=2 operators. In this paper we place two phenomenological constraints on these operators at dimension d{<=}11. First, we require that the operators obey the quark flavor symmetries of the standard model, with any violation of the symmetries being due to Yukawa interactions, a scheme known as minimal flavor violation. Second, we require that the operators which generate neutrinoless double {beta} decay, and any operators related by the flavor symmetries, do not induce neutrino masses above the experimental and astrophysical limits. We find that these requirements severely constrain the operators which can violate lepton number, such that most can no longer contribute to neutrinoless double {beta} decay at observable rates. It is noteworthy that quark flavor symmetries can play such a strong role in constraining new leptonic physics, even when that physics is not quark flavor changing. Those few operators that can mimic a Majorana neutrino mass then appear with cutoffs below a TeV, and represent new physics which could be directly probed at the LHC or a future linear collider.

  20. The MAJORANA DEMONSTRATOR: A search for neutrinoless double-beta decay of ⁷⁶Ge

    SciTech Connect (OSTI)

    Xu, W.; Abgrall, N.; Avignone, F. T.; Barabash, A. S.; Bertrand, F. E.; Brudanin, V.; Busch, M.; Buuck, M.; Byram, D.; Caldwell, A. S.; Chan, Y. -D.; Christofferson, C. D.; Cuesta, C.; Detwiler, J. A.; Efremenko, Yu; Ejiri, H.; Elliott, S. R.; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Green, M. P.; Gruszko, J.; Guinn, I.; Guiseppe, V. E.; Henning, R.; Hoppe, E. W.; Howard, S.; Howe, M. A.; Jasinski, B. R.; Keeter, K. J.; Kidd, M. F.; Konovalov, S. I.; Kouzes, R. T.; LaFerriere, B. D.; Leon, J.; MacMullin, J.; Martin, R. D.; Meijer, S. J.; Mertens, S.; Orrell, J. L.; O'Shaughnessy, C.; Overman, N. R.; Poon, A. W.P.; Radford, D. C.; Rager, J.; Rielage, K.; Robertson, R. G. H.; Romero-Romero, E.; Ronquest, M. C.; Shanks, B.; Shirchenko, M.; Snyder, N.; Suriano, A. M.; Tedeschi, D.; Trimble, J. E.; Varner, R. L.; Vasilyev, S.; Vetter, K.; Vorren, K.; White, B. R.; Wilkerson, J. F.; Wiseman, C.; Yakushev, E.; Yu, C. -H.; Yumatov, V.

    2015-05-01

    Neutrinoless double-beta (0νββ) decay is a hypothesized process where in some even-even nuclei it might be possible for two neutrons to simultaneously decay into two protons and two electrons without emitting neutrinos. This is possible only if neutrinos are Majorana particles, i.e. fermions that are their own antiparticles. Neutrinos being Majorana particles would explicitly violate lepton number conservation, and might play a role in the matter-antimatter asymmetry in the universe. The observation of neutrinoless double-beta decay would also provide complementary information related to neutrino masses. The Majorana Collaboration is constructing the MAJORANA DEMONSTRATOR, with a total of 40-kg Germanium detectors, to search for the 0νββ decay of ⁷⁶Ge and to demonstrate a background rate at or below 3 counts/(ROI•t•y) in the 4 keV region of interest (ROI) around the 2039 keV Q-value for ⁷⁶Ge 0νββ decay. In this paper, we discuss the physics of neutrinoless double beta decay and then focus on the MAJORANA DEMONSTRATOR, including its design and approach to achieve ultra-low backgrounds and the status of the experiment.

  1. The MAJORANA DEMONSTRATOR: A search for neutrinoless double-beta decay of ⁷⁶Ge

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Xu, W.; Abgrall, N.; Avignone, F. T.; Barabash, A. S.; Bertrand, F. E.; Brudanin, V.; Busch, M.; Buuck, M.; Byram, D.; Caldwell, A. S.; et al

    2015-05-01

    Neutrinoless double-beta (0νββ) decay is a hypothesized process where in some even-even nuclei it might be possible for two neutrons to simultaneously decay into two protons and two electrons without emitting neutrinos. This is possible only if neutrinos are Majorana particles, i.e. fermions that are their own antiparticles. Neutrinos being Majorana particles would explicitly violate lepton number conservation, and might play a role in the matter-antimatter asymmetry in the universe. The observation of neutrinoless double-beta decay would also provide complementary information related to neutrino masses. The Majorana Collaboration is constructing the MAJORANA DEMONSTRATOR, with a total of 40-kg Germanium detectors,more » to search for the 0νββ decay of ⁷⁶Ge and to demonstrate a background rate at or below 3 counts/(ROI•t•y) in the 4 keV region of interest (ROI) around the 2039 keV Q-value for ⁷⁶Ge 0νββ decay. In this paper, we discuss the physics of neutrinoless double beta decay and then focus on the MAJORANA DEMONSTRATOR, including its design and approach to achieve ultra-low backgrounds and the status of the experiment.« less

  2. Apparatus and method for reading two-dimensional electrophoretograms containing .beta.-ray-emitting labeled compounds

    DOE Patents [OSTI]

    Anderson, Herbert L.; Kinnison, W. Wayne; Lillberg, John W.

    1987-01-01

    Apparatus and method for electronically reading planar two dimensional .beta.-ray emitter-labeled gel electrophoretograms. A single, flat rectangular multiwire proportional chamber is placed in close proximity to the gel and the assembly placed in an intense uniform magnetic field disposed in a perpendicular manner to the rectangular face of the proportional chamber. Beta rays emitted in the direction of the proportional chamber are caused to execute helical motions which substantially preserve knowledge of the coordinates of their origin in the gel. Perpendicularly oriented, parallel wire, parallel plane cathodes electronically sense the location of the .beta.-rays from ionization generated thereby in a detection gas coupled with an electron avalanche effect resulting from the action of a parallel wire anode located therebetween. A scintillator permits the present apparatus to be rendered insensitive when signals are generated from cosmic rays incident on the proportional chamber. Resolution for concentrations of radioactive compounds in the gel exceeds 700 .mu.m. The apparatus and method of the present invention represent a significant improvement over conventional autoradiographic techniques in dynamic range, linearity and sensitivity of data collection. A concentration and position map for gel electrophoretograms having significant concentrations of labeled compounds and/or highly radioactive labeling nuclides can generally be obtained in less than one hour.

  3. Apparatus for reading two-dimensional electrophoretograms containing. beta. -ray-emitting labeled compounds

    DOE Patents [OSTI]

    Anderson, H.L.; Kinnison, W.W.; Lillberg, J.W.

    1985-04-30

    An apparatus and method for electronically reading planar two-dimensional ..beta..-ray emitter-labeled gel electrophoretograms. A single, flat rectangular multiwire proportional chamber is placed in close proximity to the gel and the assembly placed in an intense uniform magnetic field disposed in a perpendicular manner to the rectangular face of the proportional chamber. Beta rays emitted in the direction of the proportional chamber are caused to execute helical motions which substantially preserve knowledge the coordinates of their origin in the gel. Perpendicularly oriented, parallel wire, parallel plane cathodes electronically sense the location of the ..beta..-rays from ionization generated thereby in a detection gas coupled with an electron avalanche effect resulting from the action of a parallel wire anode located therebetween. A scintillator permits the present apparatus to be rendered insensitive when signals are generated from cosmic rays incident on the proportional chamber. Resolution for concentrations of radioactive compounds in the gel exceeds 700-..mu..m. The apparatus and method of the present invention represent a significant improvement over conventional autoradiographic techniques in dynamic range, linearity and sensitivity of data collection. A concentration and position map for gel electrophoretograms having significant concentrations of labeled compounds and/or highly radioactive labeling nuclides can generally be obtained in less than one hour.

  4. Beta processes in a high-temperature field and nuclear multibeta decays

    SciTech Connect (OSTI)

    Kopytin, I. V. Hussain, Imad A.

    2013-11-15

    Sources of the temperature dependence of rates of nuclear beta processes in matter of massive stars are systematized. Electron and positron beta decays and electron capture (K capture and the capture of unbound electrons) fromexcited nuclear states (thermal decays) are considered along with the photobeta decays from ground and excited nuclear states. The possible quantum degeneracy of an electron gas in matter and the degree of ionization of an atomic K shell in a high-temperature field are taken into account. For a number of multidecay odd-nuclei, the temperature dependences of the ratios of the total rates of their {beta}{sup -} decays to the sum of the total rates over all of decay modes for the same nuclei are calculated in the range of nuclear temperature from 2 to 3 Multiplication-Sign 10{sup 9} K. It is shown that the deviation of this ratio from the experimental value obtained at 'normal' temperature may be quite sizable. This circumstance should be taken into account in models that consider the problem of synthesis of nuclei in matter of massive stars.

  5. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... and Computer Engineering Georgia Institute of Technology 777 Atlantic Drive NW Atlanta, GA 30332-0250 Abstract The research presented in this report compares several real-time ...

  6. Special Report

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of any of the information or data contained in this Report. ... 2 1 - Introduction ...for the domestic uranium mining, conversion, and ...

  7. SPECIAL REPORT

    Broader source: Energy.gov (indexed) [DOE]

    Washington, DC 20585 September 3, 2015 MEMORANDUM FOR THE SECRETARY FROM: Gregory H. Friedman Inspector General SUBJECT: INFORMATION: Special Report: "The Department of Energy's...

  8. Improved limit on {theta}{sub 13} and implications for neutrino masses in neutrinoless double beta decay and cosmology

    SciTech Connect (OSTI)

    Lindner, Manfred; Merle, Alexander; Rodejohann, Werner [Physik-Department, Technische Universitaet Muenchen, James-Franck-Strasse, D-85748 Garching (Germany)

    2006-03-01

    We analyze the impact of a measurement, or of an improved bound, on {theta}{sub 13} for the determination of the effective neutrino mass in neutrinoless double beta decay and cosmology. In particular, we discuss how an improved limit on (or a specific value of) {theta}{sub 13} can influence the determination of the neutrino mass spectrum via neutrinoless double beta decay. We also discuss the interplay with improved cosmological neutrino mass searches.

  9. Final Technical Report [Cosmogenic background and shielding R&D for a Ge Neutrinoless Double Beta Decay Experiment

    SciTech Connect (OSTI)

    Guiseppe, Vince

    2013-10-01

    The USD Majorana group focused all of its effort in support of the MAJORANA DEMONSTRATOR (MJD) experiment. Final designs of the shielding subsystems are complete. Construction of the MJD shielding systems at SURF has begun and the proposed activities directly support the completion of the shield systems. The PI and the group contribute heavily to the onsite construction activities of the MJD experiment. The group led investigations into neutron and neutron-?induced backgrounds, shielding effectiveness and design, and radon backgrounds.

  10. Annual Report

    Energy Savers [EERE]

    1 2011 Annual Report to the Oak Ridge Community Annual Report to the Oak Ridge Community DOE/ORO/2399 Progress Cleanup P Progress Cleanup P 2 This report was produced by URS | CH2M Oak Ridge LLC, DOE's Environmental Management contractor for the Oak Ridge Reservation. About the Cover After recontouring and revegetation, the P1 Pond at East Tennessee Technology Park is flourishing. The contaminated pond was drained, recontoured, and restocked with fish that would not disturb the pond sediment. 1

  11. Isolation and bacterial expression of a sesquiterpene synthase CDNA clone from peppermint(mentha .chi. piperita, L.) that produces the aphid alarm pheromone (E)-.beta.-farnesene

    DOE Patents [OSTI]

    Croteau, Rodney Bruce; Wildung, Mark Raymond; Crock, John E.

    1999-01-01

    A cDNA encoding (E)-.beta.-farnesene synthase from peppermint (Mentha piperita) has been isolated and sequenced, and the corresponding amino acid sequence has been determined. Accordingly, an isolated DNA sequence (SEQ ID NO:1) is provided which codes for the expression of (E)-.beta.-farnesene synthase (SEQ ID NO:2), from peppermint (Mentha piperita). In other aspects, replicable recombinant cloning vehicles are provided which code for (E)-.beta.-farnesene synthase, or for a base sequence sufficiently complementary to at least a portion of (E)-.beta.-farnesene synthase DNA or RNA to enable hybridization therewith. In yet other aspects, modified host cells are provided that have been transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence encoding (E)-.beta.-farnesene synthase. Thus, systems and methods are provided for the recombinant expression of the aforementioned recombinant (E)-.beta.-farnesene synthase that may be used to facilitate its production, isolation and purification in significant amounts. Recombinant (E)-.beta.-farnesene synthase may be used to obtain expression or enhanced expression of (E)-.beta.-farnesene synthase in plants in order to enhance the production of (E)-.beta.-farnesene, or may be otherwise employed for the regulation or expression of (E)-.beta.-farnesene synthase, or the production of its product.

  12. Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha x piperita, L.) that produces the aphid alarm pheromone (E)-.beta.-farnesene

    DOE Patents [OSTI]

    Croteau, Rodney Bruce; Crock, John E.

    2005-01-25

    A cDNA encoding (E)-.beta.-farnesene synthase from peppermint (Mentha piperita) has been isolated and sequenced, and the corresponding amino acid sequence has been determined. Accordingly, an isolated DNA sequence (SEQ ID NO:1) is provided which codes for the expression of (E)-.beta.-farnesene synthase (SEQ ID NO:2), from peppermint (Mentha piperita). In other aspects, replicable recombinant cloning vehicles are provided which code for (E)-.beta.-farnesene synthase, or for a base sequence sufficiently complementary to at least a portion of (E)-.beta.-farnesene synthase DNA or RNA to enable hybridization therewith. In yet other aspects, modified host cells are provided that have been transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence encoding (E)-.beta.-farnesene synthase. Thus, systems and methods are provided for the recombinant expression of the aforementioned recombinant (E)-.beta.-famesene synthase that may be used to facilitate its production, isolation and purification in significant amounts. Recombinant (E)-.beta.-farnesene synthase may be used to obtain expression or enhanced expression of (E)-.beta.-famesene synthase in plants in order to enhance the production of (E)-.beta.-farnesene, or may be otherwise employed for the regulation or expression of (E)-.beta.-farnesene synthase, or the production of its product.

  13. TGF-{beta}1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-{kappa}B/IL-6/MMP-2

    SciTech Connect (OSTI)

    Binker, Marcelo G.; CBRHC Research Center, Buenos Aires ; Binker-Cosen, Andres A.; Gaisano, Herbert Y.; Cosen, Rodica H. de; Cosen-Binker, Laura I.

    2011-02-04

    Research highlights: {yields} Rac1 mediates TGF-{beta}1-induced SW1990 invasion through MMP-2 secretion and activation. {yields} NADPH-generated ROS act downstream of Rac1 in TGF-{beta}1-challenged SW1990 cells. {yields} TGF-{beta}1-stimulated ROS activate NF-{kappa}B in SW1990 cells. {yields} NF{kappa}B-induced IL-6 release is required for secretion and activation of MMP-2 in SW1990 cells. -- Abstract: Human pancreatic cancer invasion and metastasis have been found to correlate with increased levels of active matrix metalloproteinase 2 (MMP-2). The multifunctional cytokine transforming growth factor beta 1 (TGF-{beta}1) has been shown to increase both secretion of MMP-2 and invasion by several pancreatic cancer cell types. In the present study, we investigated the signaling pathway involved in TGF-{beta}1-promoted MMP-2 secretion and invasion by human pancreatic cancer cells SW1990. Using specific inhibitors, we found that stimulation of these tumor cells with TGF-{beta}1 induced secretion and activation of the collagenase MMP-2, which was required for TGF-{beta}1-stimulated invasion. Our results also indicate that signaling events involved in TGF-{beta}1-enhanced SW1990 invasiveness comprehend activation of Rac1 followed by generation of reactive oxygen species through nicotinamide adenine dinucleotide phosphate-oxidase, activation of nuclear factor-kappa beta, release of interleukin-6, and secretion and activation of MMP-2.

  14. Special Report

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Report 193 Chemical Weekly June 16, 2015 T he Japanese rightly called them the seeds of ... occur in the same ore deposits as the lanthanides and exhibit similar chemical properties. ...

  15. AUDIT REPORT

    Office of Environmental Management (EM)

    Treatment of Salt Waste at the Savannah River Site OAS-L-15-09 August 2015 U.S. Department ... Audit Report: "Treatment of Salt Waste at the Savannah River Site" BACKGROUND The ...

  16. Final Report

    SciTech Connect (OSTI)

    Biros, George

    2014-08-18

    This the final report for the project "Large-Scale Optimization for Bayesian Inference in Complex Systems," for the work in the group of the co-PI George Biros.

  17. Final Report

    SciTech Connect (OSTI)

    DeTar, Carleton

    2012-12-10

    This document constitutes the Final Report for award DE-FC02-06ER41446 as required by the Office of Science. It summarizes accomplishments and provides copies of scientific publications with significant contribution from this award.

  18. Report2

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DC, April 1983.) 8 a) R.P. Reed et al., "The Economic Effects of Fracture in the United States," (Part 1-A Synopsis of the September 30, 1982 Report to NBS by Battelle...

  19. Workshop Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    we do not know why. Complete Executive Summary (pdf) Read entire Final Report (pdf) LA-UR 10-02959 Research Needs for Material Mixing at Extremes (pdf) Image of the Cover of...

  20. FINAL REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    FINAL REPORT AEC-ERDA Research Contract AT (11-1) 2174 Columbia University's Nevis Laboratories "Research in Neutron Velocity Spectroscopy" James RainwatGr DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency Thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or

  1. FINAL REPORT

    Office of Scientific and Technical Information (OSTI)

    FINAL REPORT Analytical and Elemental Analysis of Air and Soil Samples Facility and Public Awareness Partnership (Training/Public Awareness) Congressionally Awarded Grant No. DE-FG02-05ER64045 Submitted to: U.S. Department of Energy Attn: William Henson Submitted by: Alabama A&M University Research Institute (AAMURI) [pic] October 1, 2007 This report reflects a joint training program at the Integrated Environmental Research and Services (IERS) of the Alabama A&M University Research

  2. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    REPORT SAND 2011-3958 Unlimited Release Printed June 2011 Site Environmental Report for 2010 Sandia National Laboratories, California B.L. Larsen Prepared by Sandia National Laboratories Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000. Approved for

  3. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Study of the Use of Deep Saline Formations for Combined Thermoelectric Power Plant Water Needs and Carbon Sequestration at a Regional- Scale: Phase I Report. June, 2008 Disclaimer This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or

  4. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    5-0587 Unlimited Release January 2015 Precursor Report of Data Needs and Recommended Practices for PV Plant Availability, Operations and Maintenance Reporting Roger R Hill, Geoffrey Klise; Sandia National Laboratories John R Balfour, High Performance PV Prepared by Roger Hill Sandia National Laboratories Albuquerque, New Mexico 87185 and Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of

  5. SPECIAL REPORT

    Energy Savers [EERE]

    SPECIAL REPORT Enforcement Activities Conducted by the Federal Energy Regulatory Commission DOE/IG-0947 September 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 September 29, 2015 MEMORANDUM FOR THE CHAIRMAN, FEDERAL ENERGY REGULATORY COMMISSION FROM: Gregory H. Friedman Inspector General SUBJECT: INFORMATION: Special Report: "Enforcement Activities Conducted by the Federal Energy Regulatory

  6. Reporting Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reporting Requirements Reporting Requirements Contacts Director Albert Migliori Deputy Franz Freibert 505 667-6879 Email Professional Staff Assistant Susan Ramsay 505 665 0858 Email The Fellow will be required to participate in the Actinide Science lecture series by both attending lectures and presenting a scientific lecture on actinide science in this series. Submission of a viewgraph and brief write-up of the project. Provide metrics information as requested. Submission of an overview article

  7. Final Report

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Final Report Document Number 11123-23.Final Field Demonstration of Eco-Friendly Creation of Propped Hydraulic Fractures Contract Number: 11123-23.Final February 16, 2015 Nadji Benrabah (Author) Engineer CSI Technologies 1930 W.W. Thorne Dr. Houston, TX 77073 Phil Van Trump (Principal Investigator) Chief Technology Officer DaniMer Scientific, LLC 1301 Colquitt Highway Bainbridge, GA 39817 2 LEGAL NOTICE This report was prepared by DaniMer Scientific, LLC as an account of work sponsored by the

  8. Confirmatory Survey Report for the Quehanna Decommissioning Project, Karthaus, PA

    SciTech Connect (OSTI)

    W. C. Adams

    2007-10-30

    The survey activities consisted of visual inspections and radiological surveys including beta and gamma surface scans and surface beta activity measurements.

  9. Neutrinoless double-beta decay search with CUORE and CUORE-0 experiments

    SciTech Connect (OSTI)

    Moggi, N.; Artusa, D. R.; Avignone, F. T.; Azzolini, O.; Balata, M.; Banks, T. I.; Bari, G.; Beeman, J.; Bellini, F.; Bersani, A.; Biassoni, M.; Brofferio, C.; Bucci, C.; Cai, X. Z.; Camacho, A.; Caminata, A.; Canonica, L.; Cao, X. G.; Capelli, S.; Cappelli, L.; Carbone, L.; Cardani, L.; Casali, N.; Cassina, L.; Chiesa, D.; Chott, N.; Clemenza, M.; Copello, S.; Cosmelli, C.; Cremonesi, O.; Creswick, R. J.; Cushman, J. S.; Dafinei, I.; Dally, A.; Datskov, V.; Delloro, S.; Deninno, M. M.; Di Domizio, S.; Di Vacri, M. L.; Drobizhev, A.; Ejzak, L.; Fang, D. Q.; Farach, H. A.; Faverzani, M.; Fernandes, G.; Ferri, E.; Ferroni, F.; Fiorini, E.; Franceschi, M. A.; Freedman, S. J.; Fujikawa, B. K.; Giachero, A.; Gironi, L.; Giuliani, A.; Gorla, P.; Gotti, C.; Gutierrez, T. D.; Haller, E. E.; Han, K.; Heeger, K. M.; Hennings-Yeomans, R.; Hickerson, K. P.; Huang, H. Z.; Kadel, R.; Keppel, G.; Kolomensky, Yu. G.; Li, Y. L.; Ligi, C.; Lim, K. E.; Liu, X.; Ma, Y. G.; Maiano, C.; Maino, M.; Martinez, M.; Maruyama, R. H.; Mei, Y.; Morganti, S.; Napolitano, T.; Nisi, S.; Nones, C.; Norman, E. B.; Nucciotti, A.; ODonnell, T.; Orio, F.; Orlandi, D.; Ouellet, J. L.; Pagliarone, C. E.; Pallavicini, M.; Palmieri, V.; Pattavina, L.; Pavan, M.; Pessina, G.; Pettinacci, V.; Piperno, G.; Pira, C.; Pirro, S.; Pozzi, S.; Previtali, E.; Rosenfeld, C.; Rusconi, C.; Sala, E.; Sangiorgio, S.; Santone, D.; Scielzo, N. D.; Sisti, M.; Smith, A. R.; Taffarello, L.; Tenconi, M.; Terranova, F.; Tian, W. D.; Tomei, C.; Trentalange, S.; Ventura, G.; Vignati, M.; Wang, B. S.; Wang, H. W.; Wielgus, L.; Wilson, J.; Winslow, L. A.; Wise, T.; Woodcraft, A.; Zanotti, L.; Zarra, C.; Zhang, G. Q.; Zhu, B. X.; Zucchelli, S.; Fabbri, F.; Giacomelli, P.

    2015-03-24

    The Cryogenic Underground Observatory for Rare Events (CUORE) is an upcoming experiment designed to search for the neutrinoless double-beta decays. Observation of the process would unambiguously establish that neutrinos are Majorana particles and provide information on their absolute mass scale hierarchy. CUORE is now under construction and will consist of an array of 988 TeO2 crystal bolometers operated at 10 mK, but the first tower (CUORE-0) is already taking data. The experimental techniques used will be presented as well as the preliminary CUORE-0 results. The current status of the full-mass experiment and its expected sensitivity will then be discussed.

  10. Improved-confinement plasmas at high temperature and high beta in the MST RFP

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Improved-confinement plasmas at high temperature and high beta in the MST RFP This article has been downloaded from IOPscience. Please scroll down to see the full text article. 2009 Nucl. Fusion 49 104020 (http://iopscience.iop.org/0029-5515/49/10/104020) Download details: IP Address: 128.104.166.214 The article was downloaded on 14/10/2010 at 00:22 Please note that terms and conditions apply. View the table of contents for this issue, or go to the journal homepage for more Home Search

  11. Highly stable beta-class carbonic anhydrases useful in carbon capture systems

    DOE Patents [OSTI]

    Alvizo, Oscar; Benoit, Michael R; Novick, Scott J

    2013-08-20

    The present disclosure relates to .beta.-class carbonic anhydrase polypeptides having improved properties including increased thermostability and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides formulations and uses of the polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. Also provided are polynucleotides encoding the carbonic anhydrase polypeptides and host cells capable of expressing them.

  12. Highly stable beta-class carbonic anhydrases useful in carbon capture systems

    DOE Patents [OSTI]

    Alvizo, Oscar; Benoit, Mike; Novick, Scott

    2013-04-16

    The present disclosure relates to .beta.-class carbonic anhydrase polypeptides having improved properties including increased thermostability and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides formulations and uses of the polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. Also provided are polynucleotides encoding the carbonic anhydrase polypeptides and host cells capable of expressing them.

  13. Sintering of beta-type alumina bodies using alpha-alumina encapsulation

    DOE Patents [OSTI]

    McEntire, Bryan J.; Virkar, Anil V.

    1981-01-01

    A method of sintering a shaped green, beta-type alumina body comprising: (A) inserting said body into an open chamber prepared by exposing the interior surface of a container consisting essentially of at least about 50 weight percent of alpha-alumina and a remainder of other refractory material to a sodium oxide or sodium oxide producing environment; (B) sealing the chamber; and heating the chamber with the shaped body encapsulated therein to a temperature and for a time necessary to sinter said body to the desired density. The encapsulation chamber prepared as described above is also claimed.

  14. Mechanisms of neutrinoless double-beta decay: A comparative analysis of several nuclei

    SciTech Connect (OSTI)

    Ali, A. [DESY, Deutsches Elektronen-Synchrotron (Germany); Borisov, A. V., E-mail: borisov@phys.msu.r [Moscow State University (Russian Federation); Zhuridov, D. V. [Scuola Normale Superiore (Italy)

    2010-12-15

    The neutrinoless double beta decay of several nuclei that are of interest from the experimental point of view ({sup 76}Ge, {sup 82}Se, {sup 100}Mo, {sup 130}Te, and {sup 136}Xe) is investigated on the basis of a general Lorentzinvariant effective Lagrangian describing physics effects beyond the Standard Model. The half-lives and angular-correlation coefficients for electrons are calculated for various decay mechanisms associated, in particular, with the exchange of Majorana neutrinos, supersymmetric particles (with R-parity violation), leptoquarks, and right-handed W{sub R} bosons. The effect of theoretical uncertainties in the values of relevant nuclear matrix elements on decay features is considered.

  15. Majorana phases, CP violation, sterile neutrinos and neutrinoless double-beta decay

    SciTech Connect (OSTI)

    Babi?, Andrej; imkovic, Fedor

    2013-12-30

    CP violation plays a crucial role in the generation of the baryon asymmetry in the Universe. Within this context we investigate the possibility of CP violation in the lepton sector caused by Majorana neutrino mixing. Focus is put on the model including 1 sterile neutrino. Both cases of normal and inverted neutrino mass spectrum are considered. We address the question whether the Majorana phases can be measured in the neutrinoless double-beta decay experiments with sensitivity to the effective Majorana neutrino mass of the order of 10{sup ?2} eV.

  16. Neutrinoless double-beta decay search with CUORE and CUORE-0 experiments

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Moggi, N.; Artusa, D. R.; F. T. Avignone; Azzolini, O.; Balata, M.; Banks, T. I.; Bari, G.; Beeman, J.; Bellini, F.; Bersani, A.; et al

    2015-03-24

    The Cryogenic Underground Observatory for Rare Events (CUORE) is an upcoming experiment designed to search for the neutrinoless double-beta decays. Observation of the process would unambiguously establish that neutrinos are Majorana particles and provide information on their absolute mass scale hierarchy. CUORE is now under construction and will consist of an array of 988 TeO2 crystal bolometers operated at 10 mK, but the first tower (CUORE-0) is already taking data. The experimental techniques used will be presented as well as the preliminary CUORE-0 results. The current status of the full-mass experiment and its expected sensitivity will then be discussed.

  17. Eia.gov BETA - Data - U.S. Energy Information Administration (EIA)

    Gasoline and Diesel Fuel Update (EIA)

    4/2012 - California, United States Very nice. A couple of comments. It would be good to have the option of seeing vertical lines in the graph. Also while "resetting the zoom" is an usefull option a more granular "undo" option would be more helpful. 03/02/2012 - New York, United States Finally - A great interactive webite with formatted and readable date. Great Job!!! 03/01/2012 - Brazil eia Beta became better than before. It is full, complete. The information is easy to

  18. Characterization of a large deletion in the {beta}-globin gene cluster in a newborn with hemoglobin FE

    SciTech Connect (OSTI)

    Louie, E.; Dietz, L.; Shafer, F.

    1994-09-01

    A sample on a newborn with hemoglobin FE screen results was obtained to investigate whether E/E or B/{beta}{degrees} thalassemia was present using polymerase chain reaction (PCR) methodology. The newborn appeared homozygous for the hemoglobin E mutation in our initial study, but the parents` genotypes did not support this diagnosis. The father is homozygous for the absence of the hemoglobin E mutation (non E/non E) and the mother is heterozygous (E/non E) for this mutation. The limitation of PCR analysis is an assumption that the amplification of the two {beta}-globin alleles is equivalent. A large deletion on one {beta}-globin gene, which would produce E/{beta}{degrees} thalassemia, would be missed if it included part or the entire region subjected to amplification. The family results were consistent with either non-paternity, sample mix-up or such a deletion of the {beta}-globin gene in the father and child. To rule out the possibility of non-paternity, two polymorphic loci (HLA on chromosome 6 and a VNTR system of chromosome 17) that are outside of the {beta}-globin gene were analyzed and show that inheritance is consistent and the likelihood of a sample mix-up is then reduced. We therefore believe there is a gene deletion in this family. At the present time, analyses of the RFLPs that are 5{prime} of the {beta}-globin gene cluster show that the polymorphisms most distal from the 5{prime} {beta}-globin gene are not being inherited as expected. These results support our interpretation that a deletion exists in the father and was inherited by the child. The father`s clinical picture of possible HPFH (the father has 12% hemoglobin F) also supports the interpretation of a deletion in this family. Deletions of the {beta}-globin gene within this ethnic group are rare. Currently, Southern blots on the family are being probed to determine the extent of the putative deletion.

  19. Flow cytometric analysis of expression of interleukin-2 receptor beta chain (p70-75) on various leukemic cells

    SciTech Connect (OSTI)

    Hoshino, S.; Oshimi, K.; Tsudo, M.; Miyasaka, M.; Teramura, M.; Masuda, M.; Motoji, T.; Mizoguchi, H. )

    1990-08-15

    We analyzed the expression of the interleukin-2 receptor (IL-2R) beta chain (p70-75) on various leukemic cells from 44 patients by flow cytometric analysis using the IL-2R beta chain-specific monoclonal antibody, designated Mik-beta 1. Flow cytometric analysis demonstrated the expression of the IL-2R beta chain on granular lymphocytes (GLs) from all eight patients with granular lymphocyte proliferative disorders (GLPDs), on adult T-cell leukemia (ATL) cells from all three patients with ATL, and on T-cell acute lymphoblastic leukemia (T-ALL) cells from one of three patients with T-ALL. Although GLs from all the GLPD patients expressed the IL-2R beta chain alone and not the IL-2R alpha chain (Tac-antigen: p55), ATL and T-ALL cells expressing the beta chain coexpressed the alpha chain. In two of seven patients with common ALL (cALL) and in both patients with B-cell chronic lymphocytic leukemia, the leukemic cells expressed the alpha chain alone. Neither the alpha chain nor the beta chain was expressed on leukemic cells from the remaining 28 patients, including all 18 patients with acute nonlymphocytic leukemia, five of seven patients with cALL, all three patients with multiple myeloma, and two of three patients with T-ALL. These results indicate that three different forms of IL-2R chain expression exist on leukemic cells: the alpha chain alone; the beta chain alone; and both the alpha and beta chains. To examine whether the results obtained by flow cytometric analysis actually reflect functional aspects of the expressed IL-2Rs, we studied the specific binding of 125I-labeled IL-2 (125I-IL-2) to leukemic cells in 18 of the 44 patients. In addition, we performed 125I-IL-2 crosslinking studies in seven patients. The results of IL-2R expression of both 125I-IL-2 binding assay and crosslinking studies were in agreement with those obtained by flow cytometric analysis.

  20. Oil and gas leasing in proposed wilderness areas: the Wyoming District Court's interpretation of Section 603 of the Federal Land Policy Management Act of 1976 - Rocky Mountain Oil and Gas Association v. Andrus, 500 F. Supp. 1338 (D. Wyo. 1980), appeal docketed, No. 81-1040 (10th Cir. Jan. 5, 1981)

    SciTech Connect (OSTI)

    Corbett, H.E.

    1982-01-01

    Plaintiff Rocky Mountain Oil and Gas Association, a non-profit trade association, brought suit against the Secretary of the Interior, challenging land management policies of the Department of the Interior which plaintiff contended have effectively prohibited oil and gas exploration in areas proposed as wilderness under the Federal Land Policy Management Act of 1976 (FLPMA). The principal issue at trial was Interior's interpretation of the wilderness study provisions contained in Section 603 of the Act, which directed that activities on oil and gas leases in proposed wilderness areas be managed so as to prevent impairment of wilderness values. The United States Court for the District of Wyoming, Kerr, J., held that strict application of the non-impairment standard of Section 603, FLPMA, by the Department of the Interior virtually halted oil and gas exploration in proposed wilderness areas, and is therefore statutorily erroneous, clearly contrary to Congressional intent, and counter-productive to public interest. The Trial Court's decision is being appealed to the Tenth Circuit Court of Appeals under the title Rocky Mountain Oil and Gas Association v. Watt. 91 references.

  1. Usage Reports

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reports Usage Reports Batch Job Statistics See queue wait times, hours used, top users and other summary statistics for jobs run at NERSC (login required). Read More » Parallel Job Statistics (Cray aprun) [rest... Read More » Historical Data Edison Job Size Charts Fraction of Hours Used per Job Size Note: Interactive charts with current and past Cori and Edison data are now available on MyNERSC This chart shows the fraction of hours used on Edison in each of 5 job-core-size bins. 2015 2014

  2. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    .VUQ.SAUQ.P6.02; Apply VUQ Practices With Dakota to COBRA-TF for AMA-Relevant Problems Vincent Mousseau Brian Adams Kostadin Ivanov Maria Avramova Robert Salko Taylor Blyth Sandia National Laboratories April 2013: CASL-U-2013-0048-000 SANDIA REPORT SAND2013-3093 Unlimited Release Printed April 2013 CASL L3 Milestone Report: L3:VUQ.SAUQ.P6.02; Apply VUQ Practices with Dakota to COBRA-TF for AMA-Relevant Problems Vincent Mousseau Brian Adams Kostadin Ivanov Maria Avramova Robert Salko Taylor Blyth

  3. Annual Report

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    09 THROUGH 09/30/2010 The following Annual Freedom of Information Act report covers the Period 10/01/2009, through 09/30/2010, as required by 5 U.S.C. 552. I. BASIC INFORMATION REGARDING REPORT 1. Kevin T. Hagerty, Director Office of Information Resources, MA-90 U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 202-586-5955 Alexander Morris, FOIA Officer Sheila Jeter, FOIA/Privacy Act Specialist FOIA Office, MA-90 Office of Information Resources U.S. Department of Energy

  4. Lidar Report

    SciTech Connect (OSTI)

    Wollpert.

    2009-04-01

    This report provides an overview of the LiDAR acquisition methodology employed by Woolpert on the 2009 USDA - Savannah River LiDAR Site Project. LiDAR system parameters and flight and equipment information is also included. The LiDAR data acquisition was executed in ten sessions from February 21 through final reflights on March 2, 2009; using two Leica ALS50-II 150kHz Multi-pulse enabled LiDAR Systems. Specific details about the ALS50-II systems are included in Section 4 of this report.

  5. Kinetic analysis of the phenyl-shift reaction in $\\beta$-O-4 lignin model compounds: A computational study.

    SciTech Connect (OSTI)

    Beste, Ariana; Buchanan III, A C

    2011-01-01

    The phenyl-shift reaction in $\\beta$-phenethyl phenyl ether ($\\beta - \\rm PhCH_2CH_2OPh$, $\\beta$-PPE) is an integral step in the pyrolysis of PPE, which is a model compound for the $\\beta$-O-4 linkage in lignin. We investigated the influence of natural occurring substituents (hydroxy, methoxy) on the reaction rate by calculating relative rate constant using density functional theory in combination with transition state theory, including anharmonic correction for low-frequency modes. The phenyl-shift reaction proceeds through an intermediate and the overall rate constants were computed invoking the steady-state approximation (its validity was confirmed). Substituents on the phenethyl group have only little influence on the rate constants. If a methoxy substituent is located in para position of the phenyl ring adjacent to the ether oxygen, the energies of the intermediate and second transition state are lowered, but the overall rate constant is not significantly altered. This is a consequence of the dominating first transition from pre-complex to intermediate in the overall rate constant. {\\it O}- and di-{\\it o}-methoxy substituents accelerate the phenyl-migration rate compared to $\\beta$-PPE.

  6. Characterization of Na+- beta-Zeolite Supported Pd and Pd Ag Bimetallic Catalysts using EXAFS, TEM and Flow Reactor

    SciTech Connect (OSTI)

    Huang,W.; Lobo, R.; Chen, J.

    2008-01-01

    Flow reactor studies of the selective hydrogenation of acetylene in the presence of ethylene have been performed on Na+ exchanged {beta}-zeolite supported Pd, Ag and PdAg catalysts, as an extension of our previous batch reactor studies [W. Huang, J.R. McCormick, R.F. Lobo, J.G. Chen, J. Catal. 246 (2007) 40-51]. Results from flow reactor studies show that the PdAg/Na+-{beta}-zeolite bimetallic catalyst has lower activity than Pd/Na+-{beta}-zeolite monometallic catalyst, while Ag/Na+-{beta}-zeolite does not show any activity for acetylene hydrogenation. However, the selectivity for the PdAg bimetallic catalyst is much higher than that for either the Pd catalyst or Ag catalyst. The selectivity to byproduct (ethane) is greatly inhibited on the PdAg bimetallic catalyst as well. The results from the current flow reactor studies confirmed the pervious results from batch reactor studies [W. Huang, J.R. McCormick, R.F. Lobo, J.G. Chen, J. Catal. 246 (2007) 40-51]. In addition, we used transmission electron microscope (TEM), extended X-ray absorption fine structure (EXAFS), and FTIR of CO adsorption to confirm the formation of Pd-Ag bimetallic alloy in the PdAg/Na+-{beta}-zeolite catalyst.

  7. Activity report

    SciTech Connect (OSTI)

    Yu, S W

    2008-08-11

    This report is aimed to show the author's activities to support the LDRD. The title is 'Investigation of the Double-C Behavior in the Pu-Ga Time-Temperature-Transformation Diagram' The sections are: (1) Sample Holder Test; (2) Calculation of x-ray diffraction patterns; (3) Literature search and preparing publications; (4) Tasks Required for APS Experiments; and (5) Communications.

  8. Occurrence Reporting

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1995-09-25

    To establish and maintain a system for reporting operations information related to DOE-owned or -operated facilities and processing that information to identify the root causes of Unusual, Off-Normal, and Emergency Occurrences and provide for appropriate corrective action. Cancels DOE 5000.3B.

  9. The Majorana Demonstrator: A search for neutrinoless double-beta decay of germanium-76

    SciTech Connect (OSTI)

    Elliott, S. R.; Boswell, M.; Goett, J.; Rielage, K.; Ronquest, M. C.; Xu, W. [Los Alamos National Laboratory, Los Alamos, NM (United States); Abgrall, N.; Chan, Y-D.; Hegai, A.; Martin, R. D.; Mertens, S.; Poon, A. W. P. [Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Aguayo, E.; Fast, J. E.; Hoppe, E. W.; Kouzes, R. T.; LaFerriere, B. D.; Orrell, J. L.; Overman, N. R.; Soin, A. [Pacific Northwest National Laboratory, Richland, WA (United States); and others

    2013-12-30

    The MAJORANA collaboration is searching for neutrinoless double beta decay using {sup 76}Ge, which has been shown to have a number of advantages in terms of sensitivities and backgrounds. The observation of neutrinoless double-beta decay would show that lepton number is violated and that neutrinos are Majorana particles and would simultaneously provide information on neutrino mass. Attaining sensitivities for neutrino masses in the inverted hierarchy region, 15 - 50 meV, will require large, tonne-scale detectors with extremely low backgrounds, at the level of ?1 count/t-y or lower in the region of the signal. The MAJORANA collaboration, with funding support from DOE Office of Nuclear Physics and NSF Particle Astrophysics, is constructing the DEMONSTRATOR, an array consisting of 40 kg of p-type point-contact high-purity germanium (HPGe) detectors, of which ?30 kg will be enriched to 87% in {sup 76}Ge. The DEMONSTRATOR is being constructed in a clean room laboratory facility at the 4850' level (4300 m.w.e.) of the Sanford Underground Research Facility (SURF) in Lead, SD. It utilizes a compact graded shield approach with the inner portion consisting of ultra-clean Cu that is being electroformed and machined underground. The primary aim of the DEMONSTRATOR is to show the feasibility of a future tonne-scale measurement in terms of backgrounds and scalability.

  10. Corrections to the neutrinoless double-{beta}-decay operator in the shell model

    SciTech Connect (OSTI)

    Engel, Jonathan; Hagen, Gaute [Department of Physics and Astronomy, University of North Carolina, Chapel Hill, North Carolina 27516-3255 (United States); Physics Division, Oak Ridge National Laboratory, P. O. Box 2008, Oak Ridge, Tennessee 37831 (United States)

    2009-06-15

    We use diagrammatic perturbation theory to construct an effective shell-model operator for the neutrinoless double-{beta} decay of {sup 82}Se. The starting point is the same Bonn-C nucleon-nucleon interaction that is used to generate the Hamiltonian for recent shell-model calculations of double-{beta} decay. After first summing high-energy ladder diagrams that account for short-range correlations and then adding diagrams of low order in the G matrix to account for longer-range correlations, we fold the two-body matrix elements of the resulting effective operator with transition densities from the recent shell-model calculation to obtain the overall nuclear matrix element that governs the decay. Although the high-energy ladder diagrams suppress this matrix element at very short distances as expected, they enhance it at distances between one and two fermis, so that their overall effect is small. The corrections due to longer-range physics are large, but cancel one another so that the fully corrected matrix element is comparable to that produced by the bare operator. This cancellation between large and physically distinct low-order terms indicates the importance of a reliable nonperturbative calculation.

  11. Parametric instability of a monochromatic Alfven wave: Perpendicular decay in low beta plasma

    SciTech Connect (OSTI)

    Gao, Xinliang; Lu, Quanming; Shan, Lican; Wang, Shui; Li, Xing

    2013-07-15

    Two-dimensional hybrid simulations are performed to investigate the parametric decay of a monochromatic Alfven wave in low beta plasma. Both the linearly and left-hand polarized pump Alfven waves are considered in the paper. For the linearly polarized pump Alfven wave, either a parallel or obliquely propagating wave can lead to the decay along the perpendicular direction. Initially, the parametric decay takes place along the propagating direction of the pump wave, and then the decay occurs in the perpendicular direction. With the increase of the amplitude and the propagating angle of the pump wave (the angle between the propagating direction of the pump wave and the ambient magnetic field), the spectral range of the excited waves becomes broad in the perpendicular direction. But the effects of the plasma beta on the spectral range of the excited waves in perpendicular direction are negligible. However, for the left-hand polarized pump Alfven wave, when the pump wave propagates along the ambient magnetic field, the parametric decay occurs nearly along the ambient magnetic field, and there is no obvious decay in the perpendicular direction. Significant decay in the perpendicular direction can only be found when the pump wave propagates obliquely.

  12. SELF-CONSISTENT ION CYCLOTRON ANISOTROPY-BETA RELATION FOR SOLAR WIND PROTONS

    SciTech Connect (OSTI)

    Isenberg, Philip A.; Maruca, Bennett A.; Kasper, Justin C. E-mail: bmaruca@ssl.berkeley.edu

    2013-08-20

    We derive a set of self-consistent marginally stable states for a system of ion-cyclotron waves propagating parallel to the large-scale magnetic field through a homogeneous proton-electron plasma. The proton distributions and the wave dispersions are related through the condition that no further ion-cyclotron resonant particle scattering or wave growth/damping may take place. The thermal anisotropy of the protons in these states therefore defines the threshold value for triggering the proton-cyclotron anisotropy instability. A number of recent papers have noted that the anisotropy of solar wind protons at 1 AU does not seem to be limited by the proton-cyclotron anisotropy threshold, even at low plasma beta. However, this puzzle seems to be due solely to the estimation of this anisotropy threshold under the assumption that the protons have a bi-Maxwellian distribution. We note that bi-Maxwellian distributions are never marginally stable to the resonant cyclotron interaction, so these estimates do not represent physically valid thresholds. The threshold anisotropies obtained from our marginally stable states are much larger, as a function of proton parallel beta, than the bi-Maxwellian estimates, and we show that the measured data remains below these more rigorous thresholds. Thus, the results of this paper resolve the apparent contradiction presented by the solar wind anisotropy observations at 1 AU: the bi-Maxwellian anisotropies are not rigorous thresholds, and so do not limit the proton distributions in the solar wind.

  13. Measurement of the Double-Beta Decay Half-life of {sup 136}Xe in KamLAND-Zen

    SciTech Connect (OSTI)

    KamLAND-Zen Collaboration; Gando, A.; Gando, Y.; Hanakago, H.; Ikeda, H.; Inoue, K.; Kato, R.; Koga, M.; Matsuda, S.; Mitsui, T.; Nakada, T.; Nakamura, K.; Obata, A.; Oki, A.; Ono, Y.; Shimizu, I.; Shirai, J.; Suzuki, A.; Takemoto, Y.; Tamae, K.; Ueshima, K.; Watanabe, H.; Xu, B. D.; Yamada, S.; Yoshida, H.; Kozlov, A.; Yoshida, S.; Banks, T. I.; Detwiler, J. A.; Freedman, S. J.; Fujikawa, B. K.; Han, K.; O'Donnell, T.; Berger, B. E.; Efremenko, Y.; Karwowski, H. J.; Markoff, D. M.; Tornow, W.; Enomoto, S.; Decowski, M. P.

    2012-01-23

    We present results from the KamLAND-Zen double-beta decay experiment based on an exposure of 77.6 days with 129 kg of {sup 136}Xe. The measured two-neutrino double-beta decay half-life of {sup 136}Xe is T{sup 2{nu}}{sub 1/2} = 2:38 {+-}#6; 0:02(stat)#6;{+-}0.14(syst)#2;x10{sup 21} yr, consistent with a recent measurement by EXO-200. We also obtain a lower limit for the neutrinoless double-beta decay half-life, T{sup 0{nu}}{sub 1/2} > 5.7 x#2; 10{sup 24} yr at 90% C.L.

  14. Crystal growth, structure and characterizations of a new semiorganic nonlinear optical material-{beta}-Alanine zinc chloride

    SciTech Connect (OSTI)

    Anbuchezhiyan, M.; Ponnusamy, S.; Muthamizhchelvan, C.; Sivakumar, K.

    2010-08-15

    The title compound, {beta}-alanine zinc chloride-a new semiorganic nonlinear optical crystal was grown by slow evaporation technique. Single crystals of {beta}-alanine zinc chloride have been subjected to X-ray diffraction analysis to determine the crystal structure. The powder X-ray diffractogram of the crystal has also been recorded. The amount of carbon, nitrogen and hydrogen in the crystals was also estimated. Fourier Transform Infrared and Raman spectral measurements have been carried out on the grown crystals in order to identify the functional groups. The presence of hydrogen and carbon in the {beta}-alanine zinc chloride was confirmed by using proton and carbon nuclear magnetic resonance spectral analyses. The percentage of zinc in the crystal was determined by atomic absorption spectroscopy. Optical behavior such as ultraviolet-vis-near infrared transmittance spectrum and second harmonic generation has been investigated. The mechanical strength and thermal behavior of the grown crystal have been analyzed.

  15. Realistic fission models, new beta-decay half-lives and the r-process in neutron star mergers

    SciTech Connect (OSTI)

    Shibagaki, S.; Kajino, T. [Department of Astronomy, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan and National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Chiba, S. [Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo, 152-8850 (Japan); Lorusso, G.; Nishimura, S. [RIKEN Nishina Center, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Mathews, G. J. [Center for Astrophysics, Department of Physics, University of Notre Dame, IN 46556 (United States)

    2014-05-02

    Almost half of heavy nuclei beyond iron are considered to be produced by rapid neutron capture process (r-process). This process occurs in the neutron-rich environment such as core-collapse supernovae or neutron star mergers, but the main production site is still unknown. In the r-process of neutron star mergers, nuclear fission reactions play an important role. Also beta-decay half-lives of magic nuclei are crucial for the r-process. We have carried out r-process nucleosynthesis calculations based upon new theoretical estimates of fission fragment distributions and new beta-decay half-lives for N=82 nuclei measured at RIBF-RIKEN. We investigate the effect of nuclear fission on abundance patterns in the matter ejected from neutron star mergers with two different fission fragment mass distributions. We also discuss how the new experimental beta-decay half-lives affect the r-process.

  16. Monte Carlo calculated TG-60 dosimetry parameters for the {beta}{sup -} emitter {sup 153}Sm brachytherapy source

    SciTech Connect (OSTI)

    Sadeghi, Mahdi; Taghdiri, Fatemeh; Hamed Hosseini, S.; Tenreiro, Claudio

    2010-10-15

    Purpose: The formalism recommended by Task Group 60 (TG-60) of the American Association of Physicists in Medicine (AAPM) is applicable for {beta} sources. Radioactive biocompatible and biodegradable {sup 153}Sm glass seed without encapsulation is a {beta}{sup -} emitter radionuclide with a short half-life and delivers a high dose rate to the tumor in the millimeter range. This study presents the results of Monte Carlo calculations of the dosimetric parameters for the {sup 153}Sm brachytherapy source. Methods: Version 5 of the (MCNP) Monte Carlo radiation transport code was used to calculate two-dimensional dose distributions around the source. The dosimetric parameters of AAPM TG-60 recommendations including the reference dose rate, the radial dose function, the anisotropy function, and the one-dimensional anisotropy function were obtained. Results: The dose rate value at the reference point was estimated to be 9.21{+-}0.6 cGy h{sup -1} {mu}Ci{sup -1}. Due to the low energy beta emitted from {sup 153}Sm sources, the dose fall-off profile is sharper than the other beta emitter sources. The calculated dosimetric parameters in this study are compared to several beta and photon emitting seeds. Conclusions: The results show the advantage of the {sup 153}Sm source in comparison with the other sources because of the rapid dose fall-off of beta ray and high dose rate at the short distances of the seed. The results would be helpful in the development of the radioactive implants using {sup 153}Sm seeds for the brachytherapy treatment.

  17. ASSESSMENT REPORT

    Energy Savers [EERE]

    & Wilcox Technical Services Pantex LLC During Fiscal Year 2013 Through June 30, 2014, Under Department of Energy Contract No. DE-AC54-00AL66620 OAI-V-16-04 February 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 February 12, 2016 MEMORANDUM FOR THE MANAGER, NNSA PRODUCTION OFFICE FROM: David Sedillo, Director Western Audits Division Office of Inspector General SUBJECT: INFORMATION: Assessment Report on

  18. AUDIT REPORT

    Energy Savers [EERE]

    AU Organization Chart AU Organization Chart AU Organization Chart: December 22, 2015 PDF icon AU Organization Chart: December 22, 2015 More Documents & Publications FTCP Senior Technical Safety Manager (STSM) Status Report USW Health Safety and Environment Conference - HSS Workshop Organizational Chart

    Management of the Startup of the Sodium-Bearing Waste Treatment Facility DOE-OIG-16-09 March 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections

  19. AUDIT REPORT

    Energy Savers [EERE]

    and Oversight of Information Technology Contracts at the Department of Energy's Hanford Site DOE-OIG-16-10 April 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 April 1, 2016 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Audit Report on the "Management and Oversight of Information Technology Contracts at the Department of Energy's Hanford Site"

  20. Final Report

    Office of Scientific and Technical Information (OSTI)

    Internal magnetic field, temperature, and density measurements on magnetized HED plasmas using Pulsed Polarimetry DOE Grant ER55034, UW grant # 61-9515 - High Energy Density, Office of Fusion Science Roger J Smith (PI) Dept. Aeronautics and Astronautics, University of Washington, Seattle, Wa 98195 smith@aa.washington.edu, 206 543 6323 (AA grants administrator) June 11, 2014 Report submitted to: Formerly Dr. Francis Thio Program Manager, DOE Office of Fusion Energy Sciences Nominal Grant Period:

  1. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3-3735 Unlimited Release Printed June 2013 Site Environmental Report for 2012 Sandia National Laboratories, California Barbara L. Larsen Prepared by Sandia National Laboratories Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. Approved for public

  2. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4-4161 Unlimited Release Printed June 2014 Site Environmental Report for 2013 Sandia National Laboratories, California Barbara L. Larsen Prepared by Sandia National Laboratories Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. Approved for public

  3. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2-4417 Unlimited Release Printed June 2012 Site Environmental Report for 2011 Sandia National Laboratories, California B.L. Larsen Prepared by Sandia National Laboratories Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000. Approved for public release,

  4. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    5-4277 Unlimited Release Printed June 2015 Site Environmental Report for 2014 Sandia National Laboratories, California Barbara L. Larsen Prepared by Sandia National Laboratories Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. Approved for public

  5. SANDIA REPORT

    Energy Savers [EERE]

    Russel Edge About Us Russel Edge Team Leader, Uranium Mine Team Russel Edge became an LM staff member on November 2, 2014, as a Business Management Specialist in the Westminster, Colorado, office. He reports directly to the DOE Office of Site Operations Director. Prior to joining LM, Russel was employed by the National Nuclear Security Administration Sandia field office in Albuquerque, New Mexico, as a program manager for the Laboratory Directed Research and Development (LDRD) program and point

  6. AUDIT REPORT

    Energy Savers [EERE]

    Management of Information Technology Hardware DOE/IG-0926 October 2014 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 October 30, 2014 MEMORANDUM FOR THE SECRETARY FROM: Gregory H. Friedman Inspector General SUBJECT: INFORMATION: Audit Report on "Follow-up on the Department of Energy's Management of Information Technology Hardware" BACKGROUND The Department of Energy and its facility contractors rely on

  7. AUDIT REPORT

    Energy Savers [EERE]

    Management of High-Risk Excess Facilities DOE/IG-0931 January 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 January 23, 2015 MEMORANDUM FOR THE SECRETARY FROM: Gregory H. Friedman Inspector General SUBJECT: INFORMATION: Audit Report on "The Department of Energy's Management of High-Risk Excess Facilities" BACKGROUND Fifty years of nuclear weapons production and energy research during the Manhattan

  8. AUDIT REPORT

    Energy Savers [EERE]

    Procurement of Parts and Materials for the Waste Treatment and Immobilization Plant at the Hanford Site DOE-OIG-16-03 November 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 November 17, 2015 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Audit Report: "Procurement of Parts and Materials for the Waste Treatment and Immobilization Plant at the Hanford

  9. AUDIT REPORT

    Energy Savers [EERE]

    5 Consolidated Financial Statements OAI-FS-16-01 November 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 November 16, 2015 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Audit Report: "Department of Energy's Fiscal Year 2015 Consolidated Financial Statements" Pursuant to requirements established by the Government Management Reform Act of 1994, the

  10. AUDIT REPORT

    Energy Savers [EERE]

    Issues Management at the Los Alamos Field Office OAI-M-16-02 December 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 December 7, 2015 MEMORANDUM FOR THE MANAGER, LOS ALAMOS FIELD OFFICE FROM: Daniel M. Weeber Assistant Inspector General for Audits and Administration Office of Inspector General SUBJECT: INFORMATION: Audit Report on "Issues Management at the Los Alamos Field Office" BACKGROUND The

  11. AUDIT REPORT

    Energy Savers [EERE]

    Audit of the Department of Energy's Management of Contractor Fines, Penalties, and Legal Costs DOE-OIG-16-06 February 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 February 5, 2016 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Audit Report on the "Followup Audit of the Department of Energy's Management of Contractor Fines, Penalties, and Legal

  12. AUDIT REPORT

    Energy Savers [EERE]

    Corrective Action Program at the Waste Treatment and Immobilization Plant OAI-M-16-06 February 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 February 1, 2016 MEMORANDUM FOR THE ASSISTANT SECRETARY FOR ENVIRONMENTAL MANAGEMENT FROM: George Collard Deputy Inspector General for Audits and Inspections Office of Inspector General SUBJECT: INFORMATION: Audit Report on the "Corrective Action Program at the

  13. AUDIT REPORT

    Energy Savers [EERE]

    National Laboratory DOE-OIG-16-07 February 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 February 25, 2016 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Audit Report on "Issues Management at the Los Alamos National Laboratory" BACKGROUND The Department of Energy's Los Alamos National Laboratory (LANL) is part of the National Nuclear Security

  14. Annual Report

    Energy Savers [EERE]

    Report Fiscal Year 2011 Office of Environment, Security, Safety and Health The Office of Fossil Energy: Striving for Environmental, Security, Safety and Health (ESS&H) and Sustainability Excellence I The Department of Energy's Office of Fossil Energy (FE) is dedicated to ensuring that the nation can continue to rely on traditional resources for clean, affordable energy while enhancing sustainability across its three sites: the Strategic Petroleum Reserve (SPR), the National Energy Technology

  15. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    12 Unlimited Release Printed December 2014 PV Reliability Operations and Maintenance (PVROM) Database Initiative: 2014 Progress Report Geoffrey T. Klise, Roger R. Hill, Colin J. Hamman, Peter H. Kobos, Vipin Gupta, Benjamin B. Yang, Sandia National Laboratories Nadav Enbar, Electric Power Research Institute Prepared by Sandia National Laboratories Albuquerque, New Mexico 87185 and Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by

  16. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4778 Unlimited Release July 2011 Utility-Scale Grid-Tied PV Inverter Reliability Workshop Summary Report Stanley Atcitty, Jennifer E. Granata, Michael A. Quintana, Coryne A. Tasca Prepared by Sandia National Laboratories Albuquerque, New Mexico 87185 and Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear

  17. SANDIA REPORT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    09 Unlimited Release SAND2010-7245P Printed October 2010 Annual Groundwater Monitoring Report Prepared by Sandia National Laboratories, Albuquerque, New Mexico Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. Approved for public release; further dissemination unlimited Issued

  18. AUDIT REPORT

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Consolidated Financial Statements OAI-FS-16-01 November 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 November 16, 2015 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Audit Report: "Department of Energy's Fiscal Year 2015 Consolidated Financial Statements" Pursuant to requirements established by the Government Management Reform Act of 1994, the

  19. SPECIAL REPORT

    Energy Savers [EERE]

    The Department of Energy's Freedom of Information Act Process DOE/IG-0946 September 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 September 18, 2015 MEMORANDUM FOR THE DIRECTOR, OFFICE OF MANAGEMENT FROM: Gregory H. Friedman Inspector General SUBJECT: INFORMATION: Special Report: "The Department of Energy's Freedom of Information Act Process" BACKGROUND The Freedom of Information Act (FOIA or the

  20. SPECIAL REPORT

    Energy Savers [EERE]

    Management Challenges at the Department of Energy - Fiscal Year 2016 OIG-SR-16-01 November 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 November 16, 2015 MEMORANDUM FOR THE SECRETARY FROM: Rickey R. Hass Acting Inspector General SUBJECT: INFORMATION: Special Report: "Management Challenges at the Department of Energy - Fiscal Year 2016" INTRODUCTION The Department of Energy is responsible for some

  1. CRD Report

    SciTech Connect (OSTI)

    Wang, Ucilia

    2007-12-18

    This report has the following articles: (1) Deconstructing Microbes--metagenomic research on bugs in termites relies on new data analysis tools; (2) Popular Science--a nanomaterial research paper in Nano Letters drew strong interest from the scientific community; (3) Direct Approach--researchers employ an algorithm to solve an energy-reduction issue essential in describing complex physical system; and (4) SciDAC Special--A science journal features research on petascale enabling technologies.

  2. Final Report

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cyber Security for Utility Operations NETL Project M63SNL34 Sponsored by the U.S. DOE Office of Energy Assurance Managed by NETL Final Report Period of Performance October, 2003 - April, 2005 Dennis Holstein and John Tengdin, OPUS Publishing Jay Wack and Roger Butler, TecSec, Inc. Timothy Draelos, Sandia National Laboratories 1 Paul Blomgren, SafeNet/Mykotronx April 18, 2005 1 Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States

  3. Two-stage sintering inhibits abnormal grain growth during beta to alpha transformation in SiC

    SciTech Connect (OSTI)

    Kueck, Aaron M.; De Jonghe, Lutgard C.

    2007-09-17

    Free sintering of SiC with Al, B, and C additions in two successive stages, first under nitrogen and then under argon, produced a near full-density ceramic with equiaxed grain structure. The beta to alpha transformation proceeded to completion; however, the grain shape remained equiaxed due to the action of nitrogen present during the first stage of sintering. It is found that the beta to alpha transformation is necessary but not sufficient for producing the microstructure of interlocking plates found in high-toughness SiC.

  4. Indecent disclosure - what to do with problems identified in an environment auditing report

    SciTech Connect (OSTI)

    Becker, J.C.

    1995-12-01

    During the past year, the U.S. Environmental Protection Agency (EPA) has solicited public comment on whether the federal government should be permitted to obtain the results of in-house environmental audits. This discussion was triggered, in part, by a trend in the states at the courts to treat audit reports as {open_quotes}privileged.{close_quotes} During EPA`s public meetings, industry environment managers argued that the federal government discourages environmental auditing by reserving the right to seek access to audit reports. This presentation and discussion will bring the audience up to date on proposed changes to the EPA`s policy on disclosure of environmental audit reports. It will describe the various state laws designed to protect the confidentiality of environmental audit reports and identify the criteria used by each state to qualify a report for the {open_quotes}self-audit privilege.{close_quotes} The panel will also discuss ways to establish and maintain other legal privilege claims for audit documents, and discuss what happens to privilege claims when portions of an audit report are shared with government, a potential buyer or another party. The panel will also cover the risks and benefits of documenting problems identified during a compliance review, and will explore how individual corporations decide what to do with their internal audit results.

  5. Snail/beta-catenin signaling protects breast cancer cells from hypoxia attack

    SciTech Connect (OSTI)

    Scherbakov, Alexander M.; Stefanova, Lidia B.; Sorokin, Danila V.; Semina, Svetlana E.; Berstein, Lev M.; Krasilnikov, Mikhail A.

    2013-12-10

    The tolerance of cancer cells to hypoxia depends on the combination of different factors from increase of glycolysis (Warburg Effect) to activation of intracellular growth/apoptotic pathways. Less is known about the influence of epithelialmesenchymal transition (EMT) and EMT-associated pathways on the cell sensitivity to hypoxia. The aim of this study was to explore the role of Snail signaling, one of the key EMT pathways, in the mediating of hypoxia response and regulation of cell sensitivity to hypoxia, using as a model in vitro cultured breast cancer cells. Earlier we have shown that estrogen-independent HBL-100 breast cancer cells differ from estrogen-dependent MCF-7 cells with increased expression of Snail1, and demonstrated Snail1 involvement into formation of hormone-resistant phenotype. Because Snail1 belongs to hypoxia-activated proteins, here we studied the influence of Snail1 signaling on the cell tolerance to hypoxia. We found that Snail1-enriched HBL-100 cells were less sensitive to hypoxia-induced growth suppression if compared with MCF-7 line (31% MCF-7 vs. 71% HBL-100 cell viability after 1% O{sub 2} atmosphere for 3 days). Snail1 knock-down enhanced the hypoxia-induced inhibition of cell proliferation giving the direct evidence of Snail1 involvement into cell protection from hypoxia attack. The protective effect of Snail1 was shown to be mediated, at least in a part, via beta-catenin which positively regulated expression of HIF-1-dependent genes. Finally, we found that cell tolerance to hypoxia was accompanied with the failure in the phosphorylation of AMPK the key energy sensor, and demonstrated an inverse relationship between AMPK and Snail/beta-catenin signaling. Totally, our data show that Snail1 and beta-catenin, besides association with loss of hormone dependence, protect cancer cells from hypoxia and may serve as an important target in the treatment of breast cancer. Moreover, we suggest that the level of these proteins as well the level of AMPK phosphorylation may be considered as predictors of the tumor sensitivity to anti-angiogenic drugs. - Highlights: Snail1 protects breast cancer cells from hypoxia. Protective effect of Snail1 is mediated via ?-catenin/HIF-1 pathway. Snail/?-catenin signaling is negatively controlled by the energy sensor AMPK. The failure in AMPK phosphorylation drives cells to the hypoxia-tolerant state.

  6. Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF. beta. receptor in isolated pancreatic islet cells stimulates DNA synthesis

    SciTech Connect (OSTI)

    Welsh, M.; Hallberg, A.; Welsh, N.; Arkhammar, P.; Nilsson, T.; Berggren, P.O. ); Claesson-Welsh, L.; Heldin, C.H. ); Betsholtz, C. ); Berggren, P.O. )

    1990-08-01

    Suspensions rich in pancreatic {beta} cells were transfected by means of electroporation or by using the liposome technique with DNA constructs coding for the {beta} chain of platelet-derived growth factor (PDGF) and the PDGF {alpha} and {beta} receptors to induce a mitotic response in this slowly replicating cell type. Transfection with the B-chain construct induced synthesis of the PDGF B-chain homodimer (PDGF-BB) as assessed by the presence of {sup 125}I-labeled PDGF-BB competing activity in the conditioned medium of the transfected islet cells. Moreover, islet cells transfected with the PDGF {beta}-receptor construct exhibited increased immunofluorescence staining with a PDGF {beta}-receptor antibody. These cells also displayed increased {sup 125}I-labeled PDGF-BB binding compared with control transfected cells. The {beta} cells exhibited elevated levels of ({sup 3}H)inositol trisphosphate after transfection with the B-chain and {beta}-receptor constructs, indicating activation of phospholipase C. Islet cells transfected with the different receptor constructs exhibited different patterns of tyrosine phosphorylation upon ligand activation. The results demonstrate that pancreatic islet cells can be stimulated to increase DNA synthesis by transfection with the PDGF {beta}-receptor gene, whereas cotransfection with the {alpha}-receptor gene may attenuate the growth response.

  7. Selective Hydrogenation of Acetylene in the Presence of Ethylene on K+ -beta-Zeolite Supported Pd and PdAg Catalysts

    SciTech Connect (OSTI)

    Huang,W.; Pyrz, W.; Lobo, R.; Chen, J.

    2007-01-01

    The selective hydrogenation of acetylene in the presence of ethylene has been studied on K+ exchanged {beta}-zeolite supported Pd and PdAg catalysts. Results from batch reactor studies with Fourier transform infrared spectroscopy (FTIR) have shown that the K+-{beta}-zeolite support is more selective than the Al2O3 or Na+-{beta}-zeolite supports toward the hydrogenation of acetylene. The rate and equilibrium constants for Pd/K+-{beta}-zeolite and PdAg/K+-{beta}-zeolite were determined using a Langmuir-Hinshelwood model. The selectivity of the PdAg bimetallic catalyst is twice of that of the Pd catalyst. Results from flow reactor studies show that the PdAg/K+-{beta}-zeolite catalyst has higher selectivity but lower activity toward acetylene hydrogenation than the Pd/K+-{beta}-zeolite catalyst. The selectivity to the undesirable ethane by-product is inhibited on the bimetallic catalyst. Extended X-ray absorption fine structure (EXAFS) studies and transmission electron microscope (TEM) analysis confirm the formation of Pd-Ag bimetallic bonds in the PdAg/K+-{beta}-zeolite catalyst.

  8. ASSESSMENT REPORT

    Energy Savers [EERE]

    Alliance for Sustainable Energy LLC During Fiscal Years 2012 and 2013 Under Department of Energy Contract No. DE-AC36-08GO28308 OAI-V-16-06 March 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 March 11, 2016 MEMORANDUM FOR THE DIRECTOR, GOLDEN FIELD OFFICE FROM: Jack Rouch Deputy Assistant Inspector General for Audits Office of Inspector General SUBJECT: INFORMATION: Assessment Report on "Audit Coverage

  9. ASSESSMENT REPORT

    Energy Savers [EERE]

    Stanford University During Fiscal Years 2012 and 2013 Under Department of Energy Contract No. DE-AC02-76SF00515 OAS-V-15-04 September 2015 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 September 21, 2015 MEMORANDUM FOR THE MANAGER, SLAC SITE OFFICE FROM: David Sedillo, Director Western Audits Division Office of Inspector General SUBJECT: INFORMATION: Assessment Report: "Audit Coverage of Cost Allowability for

  10. ASSESSMENT REPORT

    Energy Savers [EERE]

    Brookhaven Science Associates LLC During Fiscal Years 2012 and 2013 Under Department of Energy Contract No. DE-AC02-98CH10886 OAI-V-16-03 January 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 January 19, 2016 MEMORANDUM FOR THE MANAGER, BROOKHAVEN SITE OFFICE FROM: Jack Rouch, Director Central Audits Division Office of Inspector General SUBJECT: INFORMATION: Assessment Report: "Audit Coverage of Cost

  11. TECHNICAL REPORT

    Office of Scientific and Technical Information (OSTI)

    TECHNICAL REPORT September 1 through November 30, 1994 Project Title: MANUFACTURE OF AMMONIUM SULFATE FERTILIZER FROM FGD-GYPSUM ICCI Project Number: Principal Investigator: Other Investigators: Project Manager; DOE Cooperative Agreement Number: DE-FC22-92PC9252 1 (Year 3) 94-1/3.1B-3M M.4.M. Chou, Illinois State Geological Survey (ISGS) M. Rostam-Abadi and J.M. Lytle, ISGS R. Hoeft, University of Illinois; EZ. Blevins, Allied Signal-Chemicals; F. Achron, Southeast Marketing Chemical Process

  12. ASSESSMENT REPORT

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ASSESSMENT REPORT Audit Coverage of Cost Allowability for National Security Technologies LLC During Fiscal Years 2012 Through 2014 Under Department of Energy Contract No. DE-AC52-06NA25946 OAI-V-16-07 April 2016 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 April 12, 2016 MEMORANDUM FOR THE MANAGER, NEVADA FIELD OFFICE FROM: David Sedillo Deputy Assistant Inspector General for Audits and Inspections Office of

  13. ONTRACTOR REPORT

    Office of Scientific and Technical Information (OSTI)

    ONTRACTOR REPORT S A N D 8 2 -7 0 5 6 Unlimited Release Peer-Review Study of the Draft Handbook for Human-Reliability Analysis With Emphasis on Nuclear-Power- Plant Applications, NUREG/CR-1278 R. L. Brune, M. Weinstein, M. E. Fitzwater Human Performance Technologies, Inc. P.O. Box 3816 Thousand Oaks, CA 91359 Prepared by Sandia National Laboratories Albuquerque, New Mexico 87185 and Livermore, California 94550 for the United States D epartment of Energy under Contract DE-AC04-76DR00789 Printed

  14. Trip Report

    Office of Legacy Management (LM)

    Site A/Plot M, Cook County, Illinois May 2013 Page 1 2013 Inspection and Annual Site Status Report for the Site A/Plot M, Cook County, Illinois Decontamination and Decommissioning Program Site Summary Site A/Plot M was inspected on April 10, 2013. The site, located within a county forest preserve with significant tree and grass cover, was in good condition. No cause for a follow-up inspection was identified. Erosion on top of the grass covered mound at Plot M continues to be a concern. Bike

  15. Final Report

    SciTech Connect (OSTI)

    R Paul Drake

    2004-01-12

    OAK-B135 This is the final report from the project Hydrodynamics by High-Energy-Density Plasma Flow and Hydrodynamics and Radiation Hydrodynamics with Astrophysical Applications. This project supported a group at the University of Michigan in the invention, design, performance, and analysis of experiments using high-energy-density research facilities. The experiments explored compressible nonlinear hydrodynamics, in particular at decelerating interfaces, and the radiation hydrodynamics of strong shock waves. It has application to supernovae, astrophysical jets, shock-cloud interactions, and radiative shock waves.

  16. Thermodynamics of the Hydrolysis Reactions of 1,4-beta-D-xylobiose, 1,4-beta-D-xylotriose, D-cellobiose, and D-Maltose

    SciTech Connect (OSTI)

    Tewari, Y. B.; Lang, B. E.; Decker, S. R.; Goldberg, R. N.

    2008-10-01

    Microcalorimetry and high-performance liquid chromatography have been used to conduct a thermodynamic investigation of the following reactions: (1) 1,4-{beta}-Dxylobiose(aq)+H{sub 2}O(I)=2D-xylose(aq); (2) 1,4-{beta}-D-xylotriose+2H{sub 2}O(I)=3D-xylose(aq); (3) D-maltose(aq)+H{sub 2}O(I)=2{alpha}-D-glucose(aq); and (4) D-cellobiose(aq)+H{sub 2}O(I)=2{alpha}-D-glucose(aq). The results of the equilibrium measurements were K = (1.46 {+-} 0.15) {center_dot} 10{sup 3} for reaction (1) and K = (551 {+-} 34) for reaction (3). Although it was not possible to measure directly a value for the equilibrium constant for reaction (4), it was possible to obtain the value K = 657 for this reaction via a thermochemical pathway calculation. The results of the calorimetric measurements were standard enthalpies of reaction {Delta}{sub r}H{sup o} = (0.12 {+-} 0.26) kJ {center_dot} mol{sup -1} for reaction (1) and {Delta}{sub r}H{sup o} = -(0.06 {+-} 0.18) kJ {center_dot} mol{sup -1} for reaction (2). It is noted that values of {Delta}{sub r}H{sup o} for reactions (1) and (2) are equal to each other within their respective experimental errors. This fact is consistent with earlier observations that, for reactions involving the making/breaking of N saccharide linkages, the assignment of characteristic values of {Delta}{sub r}H{sup o}/N or {Delta}{sub r}G{sup o}/N or {Delta}{sub r}S{sup o}/N for a specified linkage, is accurate in predicting the values of {Delta}{sub r}H{sup o}, {Delta}{sub r}G{sup o}, and {Delta}{sub r}S{sup o} for reactions involving saccharides that contain multiples or combinations of such linkages. Also, the values of the standard entropy changes {Delta}{sub r}S{sup o} for the hydrolysis reactions (3) and (4) fall into the range of values {l_brace}(32 to 48) J {center_dot} K{sup -1} {center_dot} mol{sup -1}{r_brace} previously noted for the hydrolysis of six-carbon disaccharides. In order to tie the results of this study into the thermochemical literature, a reaction catalog of related property values was created. Selected property values from this reaction catalog were then used to calculate 'best' values of the standard Gibbs free energy of formation {Delta}{sub r}G{sup o}, the standard enthalpy of formation {Delta}{sub r}H{sup o}, the standard molar entropy S{sub m}{sup o}, and the standard molar heat capacity C{sub p,m}{sup o}, for the substances of interest to this investigation.

  17. Ideal magnetohydrodynamic simulations of low beta compact toroid injection into a hot strongly magnetized plasma

    SciTech Connect (OSTI)

    Liu, Wei; Hsu, Scott; Li, Hui

    2009-01-01

    We present results from three-dimensional ideal magnetohydrodynamic simulations of low {beta} compact toroid (CT) injection into a hot strongly magnetized plasma, with the aim of providing insight into CT fueling of a tokamak with parameters relevant for ITER (International Thermonuclear Experimental Reactor). A regime is identified in terms of CT injection speed and CT-to-background magnetic field ratio that appears promising for precise core fueling. Shock-dominated regimes, which are probably unfavorable for tokamak fueling, are also identified. The CT penetration depth is proportional to the CT injection speed and density. The entire CT evolution can be divided into three stages: (1) initial penetration, (2) compression in the direction of propagation and reconnection, and (3) coming to rest and spreading in the direction perpendicular to injection. Tilting of the CT is not observed due to the fast transit time of the CT across the background plasma.

  18. Surface Polarity Of Beta-hmx Crystal And The Related Adhesive Forces With Estane Binder

    SciTech Connect (OSTI)

    Yang, Lu; Hanson, David E

    2008-01-01

    Here we present the results on the study of surface properties of {beta}-HMX crystal utilizing molecular simulations. The surface polarity of three principal crystal surfaces are investigated by measuring the water contact angles. The calculated contact angles agree excellently with the values measured by experiment and show that the surface polarity of three crystal surfaces are different. The free energies and forces of detaching an Estane chain with and without nitroplasticizer from the three principal crystal surfaces were calculated using umbrella sampling technique. We find that the detaching free energy/force increases with the increasing HMX surface polarity. In addition, our results also show that nitroplasticizer plays an important role in the adhesion forces between Estane and HMX surfaces.

  19. Pair correlations in neutrinoless double {beta} decay candidate {sup 130}Te.

    SciTech Connect (OSTI)

    Bloxham, T.; Kay, B. P.; Schiffer, J. P.; Clark, J. A.; Deibel, C. M.; Freeman, S. J.; Freedman, S. J.; Howard, A. M.; McAllister, S. A.; Parker, P. D.; Sharp, D. K.; Thomas, J. S. (Physics); ( PSC-USR); (LBNL); (Michigan State Univ.); (Univ. of Manchester); (Yale Univ.)

    2010-08-16

    Pair correlations in the ground state of {sup 130}Te have been investigated using pair-transfer experiments to explore the validity of approximations in calculating the matrix element for neutrinoless double-{beta} decay. This nucleus is a candidate for the observation of such decay, and a good understanding of its structure is crucial for eventual calculations of the neutrino mass, should such a decay indeed be observed. For proton-pair adding, strong transitions to excited 0{sup +} states had been observed in the Te isotopes by Alford et al. [Nucl. Phys. A 323, 339 (1979)], indicating a breaking of the BCS approximation for protons in the ground state. We measured the neutron-pair removing (p,t) reaction on {sup 130}Te and found no indication of a corresponding splitting of the BCS nature of the ground state for neutrons.

  20. A Segmented, Enriched N-type Germanium Detector for Neutrinoless Double Beta-Decay Experiments

    SciTech Connect (OSTI)

    Leviner, L.; Aalseth, Craig E.; Ahmed, M. W.; Avignone, F. T.; Back, Henning O.; Barabash, Alexander S.; Boswell, M.; De Braeckeleer, L.; Brudanin, V.; Chan, Yuen-Dat; Egorov, Viatcheslav; Elliott, Steven R.; Gehman, Victor M.; Hossbach, Todd W.; Kephart, Jeremy; Kidd, M. F.; Konovalov, S.; Lesko, Kevin; Li, Jingyi; Mei, Dongming; Mikhailov, S.; Miley, Harry S.; Radford, D. C.; Reeves, James H.; Sandukovsky, Viatcheslav; Umatov, Valdimir; Underwood, T. A.; Tornow, W.; Wu, Y. K.; Young, A.

    2014-01-21

    We present data characterizing the performance of the _rst segmented, N- type Ge detector, isotopically enriched to 85% 76Ge. This detector, based on the Ortec PT6x2 design and referred to as SEGA (Segmented, Enriched Germanium Assembly), was developed as a possible prototype for neutrinoless double beta-decay measurements by the Majorana collaboration. We present some of the general characteristics (including bias potential, efficiency, leakage current, and integral cross-talk) for this detector in its temporary cryostat. We also present an analysis of the resolution of the detector, and demonstrate that for all but two segments there is at least one channel that reaches the Majorana resolution goal below 4 keV FWHM at 2039 keV, and all channels are below 4.5 keV FWHM.