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Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
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1

Molecular Beam Mass Spectrometry (MBMS) (Revised) (Fact Sheet)  

DOE Green Energy (OSTI)

This fact sheet provides information about Molecular Beam Mass Spectrometry (MBMS) capabilities and applications at NREL's National Bioenergy Center. NREL has six MBMS systems that researchers and industry partners can use to understand thermochemical biomass conversion and biomass composition recalcitrance.

Not Available

2011-07-01T23:59:59.000Z

2

Reflection mass spectrometry technique for monitoring and controlling composition during molecular beam epitaxy  

DOE Patents (OSTI)

This invention is comprised of a method for on-line accurate monitoring and precise control of molecular beam epitaxial growth of Groups III-III-V or Groups III-V-V layers in an advanced semiconductor device incorporates reflection mass spectrometry. The reflection mass spectrometry is responsive to intentional perturbations in molecular fluxes incident on a substrate by accurately measuring the molecular fluxes reflected from the substrate. The reflected flux is extremely sensitive to the state of the growing surface and the measurements obtained enable control of newly forming surfaces that are dynamically changing as a result of growth.

Brennan, T.M.; Hammons, B.E.; Tsao, J.Y.

1990-08-15T23:59:59.000Z

3

Reflection mass spectrometry technique for monitoring and controlling composition during molecular beam epitaxy  

DOE Patents (OSTI)

A method for on-line accurate monitoring and precise control of molecular beam epitaxial growth of Groups III-III-V or Groups III-V-V layers in an advanced semiconductor device incorporates reflection mass spectrometry. The reflection mass spectrometry is responsive to intentional perturbations in molecular fluxes incident on a substrate by accurately measuring the molecular fluxes reflected from the substrate. The reflected flux is extremely sensitive to the state of the growing surface and the measurements obtained enable control of newly forming surfaces that are dynamically changing as a result of growth.

Brennan, Thomas M. (Albuquerque, NM); Hammons, B. Eugene (Tijeras, NM); Tsao, Jeffrey Y. (Albuquerque, NM)

1992-01-01T23:59:59.000Z

4

Theoretical Mass Spectrometry  

Science Conference Proceedings (OSTI)

... Mass spectrometry is an important technique in analytical chemistry, essential in areas including drug development, criminal ... Facilities/Tools Used: ...

2013-03-19T23:59:59.000Z

5

EMSL: Capabilities: Mass Spectrometry Experts  

NLE Websites -- All DOE Office Websites (Extended Search)

Related EMSL User Projects Mass Spectrometry Tools are Applied to all Science Themes Next-Generation Mass Spectrometry Proteomics Research Resource for Integrative Biology...

6

Fundamental studies of the plasma extraction and ion beam formation processes in inductively coupled plasma mass spectrometry  

SciTech Connect

The fundamental and practical aspects are described for extracting ions from atmospheric pressure plasma sources into an analytical mass spectrometer. Methodologies and basic concepts of inductively coupled plasma mass spectrometry (ICP-MS) are emphasized in the discussion, including ion source, sampling interface, supersonic expansion, slumming process, ion optics and beam focusing, and vacuum considerations. Some new developments and innovative designs are introduced. The plasma extraction process in ICP-MS was investigated by Langmuir measurements in the region between the skimmer and first ion lens. Electron temperature (T{sub e}) is in the range 2000--11000 K and changes with probe position inside an aerosol gas flow. Electron density (n{sub e}) is in the range 10{sup 8}--10{sup 10} {sup {minus}cm }at the skimmer tip and drops abruptly to 10{sup 6}--10{sup 8} cm{sup {minus}3} near the skimmer tip and drops abruptly to 10{sup 6}--10{sup 8} cm{sup {minus}3} downstream further behind the skimmer. Electron density in the beam leaving the skimmer also depends on water loading and on the presence and mass of matrix elements. Axially resolved distributions of electron number-density and electron temperature were obtained to characterize the ion beam at a variety of plasma operating conditions. The electron density dropped by a factor of 101 along the centerline between the sampler and skimmer cones in the first stage and continued to drop by factors of 10{sup 4}--10{sup 5} downstream of skimmer to the entrance of ion lens. The electron density in the beam expansion behind sampler cone exhibited a 1/z{sup 2} intensity fall-off (z is the axial position). An second beam expansion originated from the skimmer entrance, and the beam flow underwent with another 1/z{sup 2} fall-off behind the skimmer. Skimmer interactions play an important role in plasma extraction in the ICP-MS instrument.

Niu, Hongsen

1995-02-10T23:59:59.000Z

7

EMSL: Capabilities: Mass Spectrometry: Next-Generation Mass Spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

Next-Generation Mass Spectrometry Next-Generation Mass Spectrometry Additional Information Meet the Mass Spectrometry Experts Related EMSL User Projects Mass Spectrometry Tools are Applied to all Science Themes Next-Generation Mass Spectrometry Proteomics Research Resource for Integrative Biology Biological and Environmental Research - PNNL Proteomics PNNL's Biological MS Data and Software Distribution Center Mass Spectrometry brochure EMSL is committed to offering state-of-the-art instruments to its users. At a workshop in January of 2008, EMSL mass spectrometry experts joined experts from many universities, private companies, and government institutions and laboratories at a conference held at the National High Magnetic Field Laboratory in Tallahassee Florida. Workshop participants reviewed the state of the art of high-performance mass spectrometers,

8

Single event mass spectrometry  

DOE Patents (OSTI)

A means and method for single event time of flight mass spectrometry for analysis of specimen materials. The method of the invention includes pulsing an ion source imposing at least one pulsed ion onto the specimen to produce a corresponding emission of at least one electrically charged particle. The emitted particle is then dissociated into a charged ion component and an uncharged neutral component. The ion and neutral components are then detected. The time of flight of the components are recorded and can be used to analyze the predecessor of the components, and therefore the specimen material. When more than one ion particle is emitted from the specimen per single ion impact, the single event time of flight mass spectrometer described here furnis This invention was made with Government support under Contract No. W-7405-ENG82 awarded by the Department of Energy. The Government has certain rights in the invention.

Conzemius, Robert J. (Ames, IA)

1990-01-16T23:59:59.000Z

9

EMSL: Capabilities: Mass Spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

Five linear ion traps (one with ETD) Three triple-quadrupole spectrometers Three ion mobility spectrometry (IMS) - time-of-flight (TOF) spectrometers Seventeen custom HPLC,...

10

Linear electric field mass spectrometry  

DOE Patents (OSTI)

A mass spectrometer and methods for mass spectrometry are described. The apparatus is compact and of low weight and has a low power requirement, making it suitable for use on a space satellite and as a portable detector for the presence of substances. High mass resolution measurements are made by timing ions moving through a gridless cylindrically symmetric linear electric field. 8 figs.

McComas, D.J.; Nordholt, J.E.

1992-12-01T23:59:59.000Z

11

Linear electric field mass spectrometry  

DOE Patents (OSTI)

A mass spectrometer and methods for mass spectrometry. The apparatus is compact and of low weight and has a low power requirement, making it suitable for use on a space satellite and as a portable detector for the presence of substances. High mass resolution measurements are made by timing ions moving through a gridless cylindrically symmetric linear electric field.

McComas, David J. (Los Alamos, NM); Nordholt, Jane E. (Los Alamos, NM)

1992-01-01T23:59:59.000Z

12

MASS SPECTROMETRY WITH A VERY SMALL CYCLOTRON  

E-Print Network (OSTI)

OF CALIFORNIA mm Presented at the Argonne Symposium onHigh Energy Spectrometry, Argonne NationalLaboratory, Argonne, IL, May 11-13, 1981 MASS SPECTROMETRY

Muller, R.A.

2010-01-01T23:59:59.000Z

13

Accelerator Mass Spectrometry: Extreme Sensitivity in Biological ...  

THE LLNL TECHNOLOGY COMPANY PRODUCT 24 Partnering Today: Technology Transfer Highlights Accelerator Mass Spectrometry: Extreme Sensitivity in Biological Research

14

Available Technologies: Nanostructure Initiator Mass Spectrometry ...  

Using time dependent isotopic labeling and mass spectrometry imaging, researchers at Berkeley Lab and the University of California, Berkeley have developed a ...

15

Automated Surface Sampling Probe for Mass Spectrometry  

Dr. Gary Van Berkel and colleagues have developed a liquid microjunction surface sampling probe (LMJ?SSP). The LMJ?SSP provides mass spectrometry with ...

16

Early Days of Accelerator Mass Spectrometry  

DOE R&D Accomplishments (OSTI)

Alvarez reviews his role in the development of the tandem Van de Graaff accelerator and the technique of accelerator mass spectrometry as a technique for isotope dating. (GHT)

Alvarez, L. W.

1981-05-00T23:59:59.000Z

17

Molecular-Beam Mass-Spectrometric Analyses of Hydrocarbon Flames.  

E-Print Network (OSTI)

??Laminar flat flame combustion has been studied with molecular-beam mass-spectrometry (MBMS) for a fuel-rich cyclohexane (? = 2.003) flame, a fuel-lean toluene (? = 0.895),… (more)

Gon, Saugata

2008-01-01T23:59:59.000Z

18

Giga-Dalton Mass Spectrometry  

Current techniques to study large bio?molecules using mass spectrometer require fragmentation for the mass?to?charge ratios to be within the working range of the mass spectrometer. Analysis of the data is complex and often requires simulation ...

19

Airfoil sampling of a pulsed Laval beam with tunable vacuum ultraviolet (VUV) synchrotron ionization quadrupole mass spectrometry: Application to low--temperature kinetics and product detection  

SciTech Connect

A new pulsed Laval nozzle apparatus with vacuum ultraviolet (VUV) synchrotron photoionization quadrupole mass spectrometry is constructed to study low-temperature radicalneutralchemical reactions of importance for modeling the atmosphere of Titan and the outer planets. A design for the sampling geometry of a pulsed Laval nozzle expansion has beendeveloped that operates successfully for the determination of rate coefficients by time-resolved mass spectrometry. The new concept employs airfoil sampling of the collimated expansion withexcellent sampling throughput. Time-resolved profiles of the high Mach number gas flow obtained by photoionization signals show that perturbation of the collimated expansion by theairfoil is negligible. The reaction of C2H with C2H2 is studied at 70 K as a proof-of-principle result for both low-temperature rate coefficient measurements and product identification basedon the photoionization spectrum of the reaction product versus VUV photon energy. This approach can be used to provide new insights into reaction mechanisms occurring at kinetic ratesclose to the collision-determined limit.

Soorkia, Satchin; Liu, Chen-Lin; Savee, John D.; Ferrell, Sarah J.; Leone, Stephen R.; Wilson, Kevin R.

2011-10-12T23:59:59.000Z

20

High-Performance Mass Spectrometry Facility  

NLE Websites -- All DOE Office Websites (Extended Search)

HPMSF Overview HPMSF Overview Section 2-4-1 High-Performance Mass Spectrometry Facility The High-Performance Mass Spectrometry Facility (HPMSF) provides state-of-the-art mass spectrometry (MS) and separations instrumentation that has been refined for leading-edge analysis of biological problems with a primary emphasis on proteomics. Challenging research in proteomics, cell signaling, cellular molecular machines, and high-molecular weight systems receive the highest priority for access to the facility. Current research activities in the HPMSF include proteomic analyses of whole cell lysates, analyses of organic macro-molecules and protein complexes, quantification using isotopically labeled growth media, targeted proteomics analyses of subcellular fractions, and nucleic acid analysis of

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Linear electric field mass spectrometry  

DOE Patents (OSTI)

A mass spectrometer is described having a low weight and low power requirement, for use in space. It can be used to analyze the ionized particles in the region of the spacecraft on which it is mounted. High mass resolution measurements are made by timing ions moving through a gridless cylindrically sysmetric linear electric field.

McComas, D.J.; Nordholt, J.E.

1991-03-29T23:59:59.000Z

22

Instrument Series: Mass Spectrometry SPLAT II  

NLE Websites -- All DOE Office Websites (Extended Search)

Mass Spectrometry Mass Spectrometry SPLAT II SPLAT II is a one-of-a-kind single particle mass spectrometer that was designed, constructed, and deployed at EMSL to allow users to precisely characterize the physical and chemical properties of nanoparticles. SPLAT II yields quantitative information on particle physical and chemical properties in the laboratory or in the field-even aboard an aircraft. In the context of EMSL's integrated problem-solving environment, the unique capabilities of SPLAT II enable vital research across a range of scientific fields. Research Applications Fundamental science - characterizing the properties and behavior of matter on the nanoscale Atmospheric chemistry - understanding the processes that control atmospheric aerosol life cycle Climate change - uncovering and helping

23

Monolithic multinozzle emitters for nanoelectrospray mass spectrometry  

DOE Patents (OSTI)

Novel and significantly simplified procedures for fabrication of fully integrated nanoelectrospray emitters have been described. For nanofabricated monolithic multinozzle emitters (NM.sup.2 emitters), a bottom up approach using silicon nanowires on a silicon sliver is used. For microfabricated monolithic multinozzle emitters (M.sup.3 emitters), a top down approach using MEMS techniques on silicon wafers is used. The emitters have performance comparable to that of commercially-available silica capillary emitters for nanoelectrospray mass spectrometry.

Wang, Daojing (Daly City, CA); Yang, Peidong (Kensington, CA); Kim, Woong (Seoul, KR); Fan, Rong (Pasadena, CA)

2011-09-20T23:59:59.000Z

24

Emerging Technologies in Mass Spectrometry Imaging  

E-Print Network (OSTI)

Mass spectrometry imaging (MSI) as an analytical tool for bio-molecular and bio-medical research targets, accurate compound localization and identification. In terms of dedicated instrumentation, this translates into the demand for more detail in the image dimension (spatial resolution) and in the spectral dimension (mass resolution and accuracy), preferably combined in one instrument. At the same time, large area biological tissue samples require fast acquisition schemes, instrument automation and a robust data infrastructure. This review discusses the analytical capabilities of an "ideal" MSI instrument for bio-molecular and bio-medical molecular imaging. The analytical attributes of such an ideal system are contrasted with technological and methodological challenges in MSI. In particular, innovative instrumentation for high spatial resolution imaging in combination with high sample throughput is discussed. Detector technology that targets various shortcomings of conventional imaging detector systems is hig...

Jungmann, Julia H

2013-01-01T23:59:59.000Z

25

Secondary Ion Mass Spectrometry of Environmental Aerosols  

Science Conference Proceedings (OSTI)

Atmospheric particles influence many aspects of climate, air quality and human health. Understanding the composition, chemistry and behavior of atmospheric aerosols is a key remaining challenge in improving climate models. Furthermore, particles may be traced back to a particular source based on composition, stable isotope ratios, or the presence of particular surface chemistries. Finally, the characterization of atmospheric particles in the workplace plays an important role in understanding the potential for exposure and environmental and human health effects to engineered and natural nanoscale particles. Secondary ion mass spectrometry (SIMS) is a useful tool in determining any of several aspects of the structure, composition and chemistry of these particles. Often used in conjunction with other surface analysis and electron microscopy methods, SIMS has been used to determine or confirm reactions on and in particles, the presence of particular organic species on the surface of atmospheric aerosols and several other interesting and relevant findings. Various versions of SIMS instruments – dynamic SIMS, time of flight secondary ion mass spectrometry or TOF-SIMS, nanoSIMS – have been used to determine specific aspects of aerosol structure and chemistry. This article describes the strengths of each type of SIMS instrument in the characterization of aerosols, along with guidance on sample preparation, specific characterization specific to the particular information sought in the analysis. Examples and guidance are given for each type of SIMS analysis.

Gaspar, Daniel J.; Cliff, John B.

2010-08-01T23:59:59.000Z

26

Small system for tritium accelerator mass spectrometry  

DOE Patents (OSTI)

Apparatus for ionizing and accelerating a sample containing isotopes of hydrogen and detecting the ratios of hydrogen isotopes contained in the sample is disclosed. An ion source generates a substantially linear ion beam including ions of tritium from the sample. A radio-frequency quadrupole accelerator is directly coupled to and axially aligned with the source at an angle of substantially zero degrees. The accelerator accelerates species of the sample having different mass to different energy levels along the same axis as the ion beam. A spectrometer is used to detect the concentration of tritium ions in the sample. In one form of the invention, an energy loss spectrometer is used which includes a foil to block the passage of hydrogen, deuterium and .sup.3 He ions, and a surface barrier or scintillation detector to detect the concentration of tritium ions. In another form of the invention, a combined momentum/energy loss spectrometer is used which includes a magnet to separate the ion beams, with Faraday cups to measure the hydrogen and deuterium and a surface barrier or scintillation detector for the tritium ions.

Roberts, Mark L. (Livermore, CA); Davis, Jay C. (Livermore, CA)

1993-01-01T23:59:59.000Z

27

Small system for tritium accelerator mass spectrometry  

DOE Patents (OSTI)

Apparatus for ionizing and accelerating a sample containing isotopes of hydrogen and detecting the ratios of hydrogen isotopes contained in the sample is disclosed. An ion source generates a substantially linear ion beam including ions of tritium from the sample. A radio-frequency quadrupole accelerator is directly coupled to and axially aligned with the source at an angle of substantially zero degrees. The accelerator accelerates species of the sample having different mass to different energy levels along the same axis as the ion beam. A spectrometer is used to detect the concentration of tritium ions in the sample. In one form of the invention, an energy loss spectrometer is used which includes a foil to block the passage of hydrogen, deuterium and [sup 3]He ions, and a surface barrier or scintillation detector to detect the concentration of tritium ions. In another form of the invention, a combined momentum/energy loss spectrometer is used which includes a magnet to separate the ion beams, with Faraday cups to measure the hydrogen and deuterium and a surface barrier or scintillation detector for the tritium ions.

Roberts, M.L.; Davis, J.C.

1993-02-23T23:59:59.000Z

28

Small system for tritium accelerator mass spectrometry  

DOE Patents (OSTI)

This invention is comprised of an apparatus for ionizing and accelerating a sample containing isotopes of hydrogen and detecting the ratios of hydrogen isotopes contained in the sample. An ion source generates a substantially linear ion beam including ions of tritium from the sample. A radiofrequency quadrupole accelerator is directly coupled to and axially aligned with the source at an angle of substantially zero degrees. The accelerator accelerates species of the sample having different mass to different energy levels along the same axis as the ion beam. A spectrometer is used to detect the concentration of tritium ions in the sample. In one form of the invention, an energy loss spectrometer is used which includes a foil to block the passage of hydrogen, deuterium and {sup 3}He ions, and a surface barrier or scintillation detector to detect the concentration of tritium ions. In another form of the invention, a combined momentum/energy loss spectrometer is used which includes a magnet to separate the ion beams, with Faraday cups to measure the hydrogen and deuterium and a surface barrier or scintillation detector for the tritium ions.

Roberts, M.L.; Davis, J.C.

1991-12-31T23:59:59.000Z

29

Toward laser ablation Accelerator Mass Spectrometry of actinides  

Science Conference Proceedings (OSTI)

A project to measure neutron capture cross sections of a number of actinides in a reactor environment by Accelerator Mass Spectrometry (AMS) at the ATLAS facility of Argonne National Laboratory is underway. This project will require the precise and accurate measurement of produced actinide isotopes in many (>30) samples irradiated in the Advanced Test Reactor at Idaho National Laboratory with neutron fluxes having different energy distributions. The AMS technique at ATLAS is based on production of highlycharged positive ions in an electron cyclotron resonance (ECR) ion source followed by acceleration in the ATLAS linac and mass-to-charge (m/q) measurement at the focus of the Fragment Mass Analyzer. Laser ablation was selected as the method of feeding the actinide material into the ion source because we expect it will have higher efficiency and lower chamber contamination than either the oven or sputtering techniques, because of a much narrower angular distribution of emitted material. In addition, a new multi-sample holder/changer to allow quick change between samples and a computer-controlled routine allowing fast tuning of the accelerator for different beams, are being developed. An initial test run studying backgrounds, detector response, and accelerator scaling repeatability was conducted in December 2010. The project design, schedule, and results of the initial test run to study backgrounds are discussed.

R. C. Pardo; F. G. Kondev; S. Kondrashev; C. Nair; T. Palchan; R. Scott; D. Seweryniak; R. Vondrasek; M. Paul; P. Collon; C. Deibel; M. Salvatores; G. Palmiotti; J. Berg; J. Fonnesbeck; G. Imel

2013-01-01T23:59:59.000Z

30

Characterization of phenolic resins with thermogravimetry-mass spectrometry  

Science Conference Proceedings (OSTI)

As part of an advanced material research program, thermogravimetry-mass spectrometry (TG-MS) analysis of a phenolic resin was carried out recently for the study of the curing of the prepolymer, solvent extraction, and carbonization of the polymer at high temperature in inert atmosphere. These steps are critical to the quality of the produced advanced material. In addition to TG-MS, several other complementary techniques were also employed for the analysis of the phenolic resin prepolymer and its curing and thermal degradation products. These techniques include pyrolysis-gas chromatography-mass spectrometry, direct insertion probe-mass spectrometry and gas chromatography-mass spectrometry. 7 refs., 5 figs., 3 tabs.

Chang, Cherng; Tackett, J.R.

1990-01-01T23:59:59.000Z

31

Signal variation in single particle aerosol mass spectrometry  

E-Print Network (OSTI)

Rapid and accurate detection of airborne micro-particles is currently an important problem in national security. One approach to such detection, bioaerosol mass spectrometry (BAMS), is currently under development at Lawrence ...

Wissner-Gross, Zachary Daniel

2007-01-01T23:59:59.000Z

32

The power of mass spectrometry in the detection of fraud  

Science Conference Proceedings (OSTI)

Fraudulent products cost industry billions of dollars each year. Perfumes are a good example. The power of mass spectrometry in the detection of fraud Inform Magazine Analytical Chemistry Biochemistry Biotechnology Bert Poepping Fraudulent pro

33

Apparatus And Method For Hydrogen And Oxygen Mass Spectrometry...  

NLE Websites -- All DOE Office Websites (Extended Search)

Of The Terrestrial Magnetosphere A detector element for mass spectrometry of a flux of heavy and light ions. Available for thumbnail of Feynman Center (505) 665-9090 Email...

34

Tropospheric Aerosol Chemistry via Aerosol Mass Spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

chemical information needed to interpret mass spectra. The challenge is to separate primary and secondary; anthropogenic, biogenic and biomass burning sources - and...

35

Noise reduction in negative-ion quadrupole mass spectrometry  

DOE Patents (OSTI)

This invention is comprised of a quadrupole mass spectrometer (QMS) system having an ion source, quadrupole mass filter, and ion collector/recorder system. A weak, transverse magnetic field and an electron collector are disposed between the quadrupole and ion collector. When operated in negative ion mode, the ion source produces a beam of primarily negatively-charged particles from a sample, including electrons as well as ions. The beam passes through the quadrupole and enters the magnetic field, where the electrons are deflected away from the beam path to the electron collector. The negative ions pass undeflected to the ion collector where they are detected and recorded as a mass spectrum.

Chastagner, P.

1991-12-31T23:59:59.000Z

36

Accelerator mass spectrometry as a bioanalytical tool for nutritional research  

SciTech Connect

Accelerator Mass Spectrometry is a mass spectrometric method of detecting long-lived radioisotopes without regard to their decay products or half-life. The technique is normally applied to geochronology, but recently has been developed for bioanalytical tracing. AMS detects isotope concentrations to parts per quadrillion, quantifying labeled biochemicals to attomole levels in milligram- sized samples. Its advantages over non-isotopeic and stable isotope labeling methods are reviewed and examples of analytical integrity, sensitivity, specificity, and applicability are provided.

Vogel, J.S.; Turteltaub, K.W.

1997-09-01T23:59:59.000Z

37

Single Cell Analysis Using Microfluidics Coupled to Ultrasensitive Mass Spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

Cell Analysis Using Microfluidics Coupled to Ultrasensitive Mass Cell Analysis Using Microfluidics Coupled to Ultrasensitive Mass Spectrometry PI Ryan Kelly, EMSL Co-investigators Xuefei Sun, FCSD, Bryan Linggi, EMSL, Keqi Tang, FCSD Proteomics and metabolomics measurements in their present form require large populations of cells and thus average over and obscure important heterogeneity that is present even in clonal populations cultivated under highly controlled conditions. For "real world" samples, this means that important but rare events go undetected, and the effects of stochastic expression and the microenvironment are blurred. The objective of this proposal is to combine microfluidic sample preparation and separations with the ultrasensitive mass spectrometry (MS) capability located in the EMSL to extend proteomic and

38

Resonance Ionization Mass Spectrometry System for Measurement of Environmental Samples  

Science Conference Proceedings (OSTI)

A resonance ionization mass spectrometry (RIMS) system has been developed at the National Institute of Standards and Technology (NIST) for sensitive and selective determination of radio?cesium in the environment. The overall efficiency was determined to be 4×10?7 with a combined (laser and mass spectrometer) selectivity of 108 for both 135Cs and 137Cs with respect to 133Cs. RIMS isotopic ratio measurements of 135Cs/ 137Cs were performed on a nuclear fuel burn?up sample and compared to measurements on a similar system at Pacific Northwest National Laboratory (PNNL) and to conventional thermal ionization mass spectrometry (TIMS). Results of preliminary RIMS investigations on a freshwater lake sediment sample are also discussed.

L. Pibida; C. A. McMahon; W. Nörtershäuser; B. A. Bushaw

2002-01-01T23:59:59.000Z

39

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry  

E-Print Network (OSTI)

We report the design, fabrication, and characterization of a new class of chip-scale quadrupole mass filter (QMF). The devices are completely batch fabricated using a wafer-scale process that integrates the quadrupole ...

Cheung, Kerry

40

Ion source for high-precision mass spectrometry  

DOE Patents (OSTI)

The invention is directed to a method for increasing the precision of positive-ion relative abundance measurements conducted in a sector mass spectrometer having an ion source for directing a beam of positive ions onto a collimating slit. The method comprises incorporating in the source an electrostatic lens assembly for providing a positive-ion beam of circular cross section for collimation by the slit.

Todd, Peter J. (Oak Ridge, TN); McKown, Henry S. (Oak Ridge, TN); Smith, David H. (Oak Ridge, TN)

1984-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

BEAM RELATED SYSTEMATICS IN HIGGS BOSON MASS MEASUREMENT  

E-Print Network (OSTI)

BEAM RELATED SYSTEMATICS IN HIGGS BOSON MASS MEASUREMENT A.RASPEREZA DESY, Notkestrasse 85, D­22607#erential luminosity spectrum measurements and beam energy spread on the precision of the Higgs boson mass measurement possible impact of the beam related systematic errors on the Higgs boson mass measurement is discussed

42

Fission Yield Measurements by Inductively Coupled Plasma Mass-Spectrometry  

SciTech Connect

Correct prediction of the fission products inventory in irradiated nuclear fuels is essential for accurate estimation of fuel burnup, establishing proper requirements for spent fuel transportation and storage, materials accountability and nuclear forensics. Such prediction is impossible without accurate knowledge of neutron induced fission yields. Unfortunately, the accuracy of the fission yields reported in the ENDF/B-VII.0 library is not uniform across all of the data and much of the improvement is desired for certain isotopes and fission products. We discuss our measurements of cumulative fission yields in nuclear fuels irradiated in thermal and fast reactor spectra using Inductively Coupled Plasma Mass Spectrometry.

Irina Glagolenko; Bruce Hilton; Jeffrey Giglio; Daniel Cummings; Karl Grimm; Richard McKnight

2009-11-01T23:59:59.000Z

43

Conditioning of ion sources for mass spectrometry of plasmas  

DOE Green Energy (OSTI)

Mass spectrometry is a useful diagnostic technique for monitoring plasma species and plasma-surface interactions. In order to maximize the sensitivity of measurements of hydrogen-fueled fusion plasmas or hydrogen-based discharge cleaning and etching plasmas, the ion sources of mass spectrometers are operated at or near the high pressure limit of 10/sup -4/ Torr (10/sup -2/ Pa). Such high ambient pressures of hydrogen give rise to high background levels of residual gases such as H/sub 2/O, CO, and CH/sub 4/, due to surface reactions on the ion source electrodes. For a commonly used ion source configuration, the residual gas production is a linear function of the ambient H/sub 2/ pressure. Hydrogen conditioning can reduce the absolute residual gas levels. Steady-state residual gas production is observed in a conditioned ion source, which is related to a balance of diffusion and sorption on the electrode surfaces.

Dylla, H.F.; Blanchard, W.R.

1983-02-01T23:59:59.000Z

44

Method for predicting peptide detection in mass spectrometry  

SciTech Connect

A method of predicting whether a peptide present in a biological sample will be detected by analysis with a mass spectrometer. The method uses at least one mass spectrometer to perform repeated analysis of a sample containing peptides from proteins with known amino acids. The method then generates a data set of peptides identified as contained within the sample by the repeated analysis. The method then calculates the probability that a specific peptide in the data set was detected in the repeated analysis. The method then creates a plurality of vectors, where each vector has a plurality of dimensions, and each dimension represents a property of one or more of the amino acids present in each peptide and adjacent peptides in the data set. Using these vectors, the method then generates an algorithm from the plurality of vectors and the calculated probabilities that specific peptides in the data set were detected in the repeated analysis. The algorithm is thus capable of calculating the probability that a hypothetical peptide represented as a vector will be detected by a mass spectrometry based proteomic platform, given that the peptide is present in a sample introduced into a mass spectrometer.

Kangas, Lars [West Richland, WA; Smith, Richard D [Richland, WA; Petritis, Konstantinos [Richland, WA

2010-07-13T23:59:59.000Z

45

Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry  

DOE Patents (OSTI)

The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).

Vertes, Akos; Nemes, Peter

2013-07-16T23:59:59.000Z

46

Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry  

DOE Patents (OSTI)

The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).

Vertes, Akos; Nemes, Peter

2013-07-16T23:59:59.000Z

47

Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry  

DOE Patents (OSTI)

The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).

Vertes, Akos; Nemes, Peter

2012-10-30T23:59:59.000Z

48

Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry  

SciTech Connect

The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI).

Vertes, Akos (Reston, VA); Nemes, Peter (Silver Spring, MD)

2011-11-29T23:59:59.000Z

49

Accelerator Mass Spectrometry | U.S. DOE Office of Science (SC...  

Office of Science (SC) Website

Accelerator Mass Spectrometry at ANL and ORNL Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Spinoff Applications Spinoff Archives SBIR...

50

Instrumentation development for coupling ion/ion reactions and ion mobility in biological mass spectrometry.  

E-Print Network (OSTI)

??The development of mass spectrometry (MS) instrumentation for novel biological applications, specifically, the development of instrumentation that integrates ion/ion reaction capabilities in an ion trap… (more)

Soyk, Matthew William

2008-01-01T23:59:59.000Z

51

Mass Spectrometry for Translational Proteomics: Progress and Clinical Implications  

SciTech Connect

Mass spectrometry (MS)-based proteomics measurements have become increasingly utilized in a wide range of biological and biomedical applications, and have significantly enhanced the understanding of the complex and dynamic nature of the proteome and its connections to biology and diseases. While some MS techniques such as those for targeted analysis are increasingly applied with great success, others such as global quantitative analysis (for e.g. biomarker discovery) are more challenging and continue to be developed and refined to provide the desired throughput, sensitivity and/ or specificity. New MS capabilities and proteomics-based pipelines/strategies also keep enhancing for the advancement of clinical proteomics applications such as protein biomarker discovery and validation. Herein, we provide a brief review to summarize the current state of MS-based proteomics with respect to its advantages and present limitations, while highlighting its potential in future clinical applications.

Baker, Erin Shammel; Liu, Tao; Petyuk, Vladislav A.; Burnum-Johnson, Kristin E.; Ibrahim, Yehia M.; Anderson, Gordon A.; Smith, Richard D.

2012-08-31T23:59:59.000Z

52

Proteomics by FTICR Mass Spectrometry: Top Down and Bottom Up  

SciTech Connect

This review offers a broad overview of recent FTICR applications and technological developments in the field of proteomics, directed to a variety of people with different expertise and interests. Both the ''bottom-up'' (peptide level) and ''top-down'' (intact protein level) approaches will be covered and various related aspects will be discussed and illustrated with examples that are among the best available references in the literature. ''Bottom-up topics include peptide fragmentation, the AMT approach and DREAMS technology, quantitative proteomics, post-translational modifications, and special FTICR software focused on peptide and protein identification. Topics in the ''top-down'' part include various aspects of high-mass measurements, protein tandem mass spectrometry, protein confirmations, protein-protein complexes, as well as some esoteric applications that may become more practical in the coming years. Finally, examples of integrating both approaches and medical proteomics applications using FTICR will be provided, closing with an outlook of what may be coming our way sooner than later.

Bogdanov, Bogdan; Smith, Richard D.

2005-03-31T23:59:59.000Z

53

Developing Fieldable Systems for Chemical Sensing Using Field Asymmetric Ion Mobility Spectrometry and Mass Spectrometry  

SciTech Connect

Currently, there is an urgent need for field-rugged and field-programmable sensor systems that provide highly selective, universal monitoring of vapors and aerosols at detectable levels from persons or areas involved with illicit chemical/biological/explosives (CBE) production. These devices must be portable, low cost, robust, and provide accurate measurements to avoid both false positive and negative results. Furthermore, the information provided by the devices must be received in a timely manner so that informed decisions can be immediately made and the appropriate actions taken. Two technologies that are unparalleled in their sensitivity, selectivity, and trace-level detection capabilities are field asymmetric ion mobility spectrometry (FAIMS) and mass spectrometry. Here, we will show progress that has been made toward developing fieldable FAIMS systems and mass spectrometers. Working in collaboration with Sionex Corporation, the microDMx detector was equipped with a continuous air sampling system to develop selective methods for the analysis of compounds of interest. A microdiaphragm pump (KNF Neuberger, Inc.) is used to pull in gas-phase analytes directly from the air for separation and detection with the FAIMS system. The FAIMS evaluation platform (SVAC) unit currently measures 9.8-inch x 4.6-inch x 3.2-inch, weighs 3.1 lb, and utilizes a {sup 63}Ni source to ionize incoming compounds. Analytes entering the unit are separated and identified by their characteristic response to the compensation voltage (V{sub c}) at a given rf field strength (V{sub rf}). This response has been observed to be unique for a wide range of substances studied. If additional verification were required or a targeted analyte present in a complex chemical matrix, a FAIMS unit equipped with a fast gas chromatography column has been evaluated. The unit combines the separation capabilities of gas chromatography with the selectivity of FAIMS. It measures 9.5-inch x 5.25-inch x 3.5-inch, weighs 3.8 lb, and uses a 10.6 eV photoionization source. Analytes are identified both by their elution time from the column and by the characteristic response in the FAIMS spectrum. Analysis times required to obtain results for most analytes examined are less than three minutes. A fieldable mass spectrometer system is also being developed that includes sampling, ionization, mass selection and detection, vacuum technology, and analytical methodology with remote data transmission. Multiple methods for mass selection are being explored, including both Penning and Paul type ion traps as well as a quadrupole system to determine which is best suited for a portable mass spectrometer. Several ionization sources and ion counting methods will also be evaluated to establish their effectiveness with each system. The intended result of this project is a handheld mass spectrometer system capable of field deployment for the detection and identification of a wide range of gas-phase CBE species.

Kevin Kyle, Stephan Weeks, R. Trainham

2008-03-01T23:59:59.000Z

54

Transition of Iodine Analysis to Accelerator Mass Spectrometry  

SciTech Connect

Funding was received from NA-22 to investigate transitioning iodine isotopic analyses to an accelerator mass spectrometry (AMS) system. The present method uses gas-phase chemistry followed by thermal ionization mass spectrometry (TIMS). It was anticipated that the AMS approach could provide comparable data, with improved background levels and superior sample throughput. An aqueous extraction method was developed for removal of iodine species from high-volume air filters. Ethanol and sodium hydroxide, plus heating and ultrasonic treatment, were used to successfully extract iodine from loaded high-volume air filters. Portions of the same filters were also processed in the traditional method and analyzed by TIMS for comparison. Aliquot parts of the aqueous extracts were analyzed by AMS at the Swiss Federal Institute of Technology. Idaho National Laboratory (INL) personnel visited several AMS laboratories in the US, Spain, and Switzerland. Experience with AMS systems from several manufacturers was gained, and relationships were developed with key personnel at the laboratories. Three batches of samples were analyzed in Switzerland, and one in Spain. Results show that the INL extraction method successfully extracted enough iodine from high-volume air filters to allow AMS analysis. Comparison of the AMS and TIMS data is very encouraging; while the TIMS showed about forty percent more atoms of 129I, the 129/127 ratios tracked each other very well between the two methods. The time required for analysis is greatly reduced for the aqueous extraction/AMS approach. For a hypothetical batch of thirty samples, the AMS methodology is about five times faster than the traditional gas-phase chemistry and TIMS analysis. As an additional benefit, background levels for the AMS method are about 1000 times lower than for TIMS. This results from the fundamental mechanisms of ionization in the AMS system and cleanup of molecular interferences. We showed that an aqueous extraction of high-volume air filters, followed by isotopic analysis by AMS, can be used successfully to make iodine measurements with results comparable to those obtained by filter combustion and TIMS analysis.

J. E. Delmore

2010-09-01T23:59:59.000Z

55

Extension of the Focusable Mass Range in Distance-of-Flight Mass Spectrometry with Multiple Detectors  

SciTech Connect

Since the underlying theory of Distance-of-Flight Mass Spectrometry (DOFMS) was reported in 2007,[1] laboratory results[2, 3] have proven its practical viability. However, these previous implementations of DOFMS considered ion detection only over narrow DOF-detection windows, with 25-mm being the greatest detection length explored. These small mass windows cannot be used to evaluate how DOFMS focusing performs over greater DOF detection lengths and mass ranges. In the present study, we expand on previous studies by placing two spatially selective ion detectors along the detection plane of the DOFMS instrument. Ion signals are simultaneously collected from both DOF detectors in order to simulate DOFMS performance with a longer spatially selective ion detector.

Gundlach-Graham, Alexander W.; Dennis, Elise; Ray, Steven J.; Enke, Christie G.; Carado, Anthony J.; Barinaga, Charles J.; Koppenaal, David W.; Hieftje, Gary M.

2012-11-15T23:59:59.000Z

56

Laser desorption mass spectrometry for fast DNA analysis  

SciTech Connect

During the past few years, major effort has been directed toward developing mass spectrometry to measure biopolymers because of the great potential benefit to biomedical research. Hellenkamp and his co-workers were the first to report that large polypeptide molecules can be ionized and detected without significant fragmentation when a greater number of nicotinic acid molecules are used as a matrix. This method is now well known as matrix-assisted laser desorption/ionization (MALDI). Since then, various groups have reported measurements of very large proteins by MALDI. Reliable protein analysis by MALDI is more or less well established. However, the application of MALDI to nucleic acids analysis has been found to be much more difficult. Most research on the measurement of nucleic acid by MALDI were stimulated by the Human Genome Project. Up to now, the only method for reliable routine analysis of nucleic acid is gel electrophoresis. Different sizes of nucleic acids can be separated in gel medium when a high electric field is applied to the gel. However, the time needed to separate different sizes of DNA segments usually takes from several minutes to several hours. If MALDI can be successfully used for nucleic acids analysis, the analysis time can be reduced to less than I millisecond. In addition, no tagging with radioactive materials or chemical dyes is needed. In this work, we will review recent progress related to MALDI for DNA analysis.

Chen, C.H.; Ch`ang, L.Y.; Taranenko, N.I.; Allman, S.L.; Tang, K.; Matteson, K.J.

1995-09-01T23:59:59.000Z

57

Accelerator Mass Spectrometry | U.S. DOE Office of Science (SC)  

Office of Science (SC) Website

Accelerator Mass Spectrometry at ANL Accelerator Mass Spectrometry at ANL and ORNL Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Spinoff Applications Spinoff Archives SBIR/STTR Applications of Nuclear Science and Technology Funding Opportunities Nuclear Science Advisory Committee (NSAC) News & Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: sc.np@science.doe.gov More Information » Spinoff Archives Accelerator Mass Spectrometry at ANL and ORNL Print Text Size: A A A RSS Feeds FeedbackShare Page Application/instrumentation: Accelerator Mass Spectrometry at ANL and ORNL Developed at: Argonne National Laboratory (ANL), Oak Ridge National Laboratory (ORNL)

58

CNT-based gas ionizers with integrated MEMS gate for portable mass spectrometry applications  

E-Print Network (OSTI)

We report the fabrication and experimental characterization of a novel low-cost carbon nanotube (CNT)-based electron impact ionizer (EII) with integrated gate for portable mass spectrometry applications. The device achieves ...

Velasquez-Garcia, Luis Fernando

59

CNT-based MEMS/NEMS gas ionizers for portable mass spectrometry applications  

E-Print Network (OSTI)

We report the fabrication and experimental characterization of a carbon nanotube (CNT)-based MEMS/NEMS electron impact gas ionizer with an integrated extractor gate for portable mass spectrometry. The ionizer achieves ...

Velasquez-Heller, Luis Fernand

60

Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight  

DOE Data Explorer (OSTI)

This deposition includes the aerosol diffraction images used for phasing, fractal morphology, and time-of-flight mass spectrometry. Files in this deposition are ordered in subdirectories that reflect the specifics.

Loh, N. Duane

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Measurements of Volatile Organic Compounds Using Proton Transfer Reaction - Mass Spectrometry during the MILAGRO 2006 Campaign  

E-Print Network (OSTI)

Volatile organic compounds (VOCs) were measured by proton transfer reaction – mass spectrometry (PTR-MS) on a rooftop in the urban mixed residential and industrial area North Northeast of downtown Mexico City as part of ...

Fortner, E. C.

62

C60 Secondary Ion Fourier Transform Ion Cyclotron Resonance Mass Spectrometry  

SciTech Connect

Secondary ion mass spectrometry (SIMS) has seen increased application for high spatial chemical imaging of complex biological surfaces. The advent and commercial availability of cluster and polyatomic primary ion sources (e.g. Au and Bi cluster and buckminsterfullerene (C60)) provide improved secondary ion yield and decreased fragmentation of surface species, thus accessibility to intact molecular ions. Despite developments in primary ion sources, development of mass spectrometers to fully exploit their advantages has been limited. Tandem mass spectrometry for identification of secondary ions is highly desirable, but implementation has proven to be difficult. Similarly, high mass resolution and high mass measurement accuracy would greatly improve the chemical specificity of SIMS. Here we combine, for the first time, the advantages of a C60 primary ion source with the ultra-high mass resolving power and high mass measurement accuracy of Fourier transform ion cyclotron resonance mass spectrometry. Mass resolving power in excess of 100,000 (m/?m50%) is demonstrated, with mass measurement accuracies below 3 parts-per-million. Imaging of mouse brain tissue at 40 ?m pixel size is shown. Tandem mass spectrometry of ions from biological tissue is demonstrated and molecular formulae can be assigned to fragment ions.

Smith, Donald F.; Robinson, Errol W.; Tolmachev, Aleksey V.; Heeren, Ronald M.; Pasa-Tolic, Ljiljana

2011-12-15T23:59:59.000Z

63

RAPID DETERMINATION OF 237 NP AND PU ISOTOPES IN WATER BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY AND ALPHA SPECTROMETRY  

Science Conference Proceedings (OSTI)

A new method that allows rapid preconcentration and separation of plutonium and neptunium in water samples was developed for the measurement of {sup 237}Np and Pu isotopes by inductively-coupled plasma mass spectrometry (ICP-MS) and alpha spectrometry; a hybrid approach. {sup 238}U can interfere with {sup 239}Pu measurement by ICP-MS as {sup 238}UH{sup +} mass overlap and {sup 237}Np via peak tailing. The method provide enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then moving Pu to DGA resin for additional removal of uranium. The decontamination factor for uranium from Pu is almost 100,000 and the decontamination factor for U from Np is greater than 10,000. This method uses stacked extraction chromatography cartridges and vacuum box technology to facilitate rapid separations. Preconcentration is performed using a streamlined calcium phosphate precipitation method. Purified solutions are split between ICP-MS and alpha spectrometry so that long and short-lived Pu isotopes can be measured successfully. The method allows for simultaneous extraction of 20 samples (including QC samples) in 4 to 6 hours, and can also be used for emergency response. {sup 239}Pu, {sup 242}Pu and {sup 237}Np were measured by ICP-MS, while {sup 236}Pu, {sup 238}Pu, and {sup 239}Pu were measured by alpha spectrometry.

Maxwell, S.; Jones, V.; Culligan, B.; Nichols, S.; Noyes, G.

2010-06-23T23:59:59.000Z

64

Structural determination of intact proteins using mass spectrometry  

DOE Patents (OSTI)

The present invention relates to novel methods of determining the sequence and structure of proteins. Specifically, the present invention allows for the analysis of intact proteins within a mass spectrometer. Therefore, preparatory separations need not be performed prior to introducing a protein sample into the mass spectrometer. Also disclosed herein are new instrumental developments for enhancing the signal from the desired modified proteins, methods for producing controlled protein fragments in the mass spectrometer, eliminating complex microseparations, and protein preparatory chemical steps necessary for cross-linking based protein structure determination.Additionally, the preferred method of the present invention involves the determination of protein structures utilizing a top-down analysis of protein structures to search for covalent modifications. In the preferred method, intact proteins are ionized and fragmented within the mass spectrometer.

Kruppa, Gary (San Francisco, CA); Schoeniger, Joseph S. (Oakland, CA); Young, Malin M. (Livermore, CA)

2008-05-06T23:59:59.000Z

65

Apparatus for preparing a sample for mass spectrometry  

DOE Patents (OSTI)

Disclosed is an apparatus for preparing a sample for analysis by a mass spectrometer system. The apparatus has an entry chamber and an ionization chamber separated by a skimmer. A capacitor having two space-apart electrodes followed by one or more ion-imaging lenses is disposed in the ionization chamber. The chamber is evacuated and the capacitor is charged. A valve injects a sample gas in the form of sample pulses into the entry chamber. The pulse is collimated by the skimmer and enters the ionization chamber. When the sample pulse passes through the gap between the electrodes, it discharges the capacitor and is thereby ionized. The ions are focused by the imaging lenses and enter the mass analyzer, where their mass and charge are analyzed.

Villa-Aleman, E.

1992-12-31T23:59:59.000Z

66

Dynamic mass spectrometry: a residual gas analysis method and some applications  

SciTech Connect

Dynamic mass spectrometry is a unique method of residual gas analysis used to monitor and trouble-shoot industrial vacuum process operations. This discussion presents applications and results of the method, and describes the equipment and analytical method developed at Rocky Flats to perform this work. GHT)

McFeeters, T.L.

1981-01-01T23:59:59.000Z

67

High resolution mass spectrometry for the characterization of complex, fossil organic mixtures  

SciTech Connect

High resolution chemical ionization mass spectrometry data support the notion that the size of the stable aromatic clusters is not large in coals except the very high rank coals and inertinite macerals. The desorption chemical ionization spectra appear representative of the sample with little discrimination for molecular types such as aliphatics.

Winans, R.E.; Haas, G.W.; Kim, Yeonhee L.; Hunt, J.E.

1995-08-01T23:59:59.000Z

68

International Journal of Mass Spectrometry 291 (2010) 108117 Contents lists available at ScienceDirect  

E-Print Network (OSTI)

Direct International Journal of Mass Spectrometry journal homepage: www.elsevier.com/locate/ijms Detection of radiation-exposure Keywords: Metabolomic Radiation exposure DMS Ion mobility Electrospray a b s t r a c t Technology to enable rapid screening for radiation exposure has been identified as an important need, and, as a part of a NIH

Brenner, David Jonathan

69

Photon burst mass spectrometry--ultrasensitive detection of rare isotopes  

SciTech Connect

Progress is reported on the development of a new technique for measurement of trace levels of radioisotopes which is based on fluorescence detection of output from a mass spectrometer. Significant achievements include the observation of fluorescence and burst signals from Kr isotopes, including enriched samples of {sup 85}Kr with a 4-collector system. An abundance sensitivity is demonstrated with {sup 83}Kr and {sup 85}Kr.

Hansen, C.S.; Pan, X.J.; Fairbank, W.M. Jr. [Colorado State Univ., Fort Collins, CO (United States). Physics Dept.; Oona, H.; Chamberlin, E.P.; Nogar, N.S.; Fearey, B.L. [Los Alamos National Lab., NM (United States)

1995-02-01T23:59:59.000Z

70

Inductively Coupled Plasma Mass Spectrometry Uranium Error Propagation  

SciTech Connect

The Hazards Control Department at Lawrence Livermore National Laboratory (LLNL) uses Inductively Coupled Plasma Mass Spectrometer (ICP/MS) technology to analyze uranium in urine. The ICP/MS used by the Hazards Control Department is a Perkin-Elmer Elan 6000 ICP/MS. The Department of Energy Laboratory Accreditation Program requires that the total error be assessed for bioassay measurements. A previous evaluation of the errors associated with the ICP/MS measurement of uranium demonstrated a {+-} 9.6% error in the range of 0.01 to 0.02 {micro}g/l. However, the propagation of total error for concentrations above and below this level have heretofore been undetermined. This document is an evaluation of the errors associated with the current LLNL ICP/MS method for a more expanded range of uranium concentrations.

Hickman, D P; Maclean, S; Shepley, D; Shaw, R K

2001-07-01T23:59:59.000Z

71

Quantitative Analysis of Tetramethylenedisulfotetramine ("Tetramine") Spiked into Beverages by Liquid Chromatography Tandem Mass Spectrometry with Validation by Gas Chromatography Mass Spectrometry  

Science Conference Proceedings (OSTI)

Tetramethylenedisulfotetramine, commonly known as tetramine, is a highly neurotoxic rodenticide (human oral LD{sub 50} = 0.1 mg/kg) used in hundreds of deliberate food poisoning events in China. Here we describe a method for quantitation of tetramine spiked into beverages, including milk, juice, tea, cola, and water and cleaned up by C8 solid phase extraction and liquid-liquid extraction. Quantitation by high performance liquid chromatography tandem mass spectrometry (LC/MS/MS) was based upon fragmentation of m/z 347 to m/z 268. The method was validated by gas chromatography mass spectrometry (GC/MS) operated in SIM mode for ions m/z 212, 240, and 360. The limit of quantitation was 0.10 {micro}g/mL by LC/MS/MS versus 0.15 {micro}g/mL for GC/MS. Fortifications of the beverages at 2.5 {micro}g/mL and 0.25 {micro}g/mL were recovered ranging from 73-128% by liquid-liquid extraction for GC/MS analysis, 13-96% by SPE and 10-101% by liquid-liquid extraction for LC/MS/MS analysis.

Owens, J; Hok, S; Alcaraz, A; Koester, C

2008-11-13T23:59:59.000Z

72

Direct analysis of cellulose in poplar stem by matrixassisted laser desorption/ionization imaging mass spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

analysis analysis of cellulose in poplar stem by matrix- assisted laser desorption/ionization imaging mass spectrometry Seokwon Jung 1,3 , Yanfeng Chen 3 , M. Cameron Sullards 1,3 and Arthur J. Ragauskas 1,2,3 * 1 BioEnergy Science Center, Georgia Institute of Technology, 500 10 th St., Atlanta, GA 30332, USA 2 Institute of Paper Science and Technology, Georgia Institute of Technology, 500 10 th St., Atlanta, GA 30332, USA 3 School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332, USA Received 10 July 2010; Revised 9 August 2010; Accepted 23 August 2010 Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) was applied to the analysis of the spatial distribution of cellulose on a cross-section of juvenile poplar (Populus deltoids) stems. Microcrystalline cellulose (MCC) was used to optimize matrix (2,5-dihydroxybenzoic

73

Tandem mass spectrometry for characterization of high-carbon-number geoporphyrins  

Science Conference Proceedings (OSTI)

Geoporphyrins are separated into TCL fractions after being isolated from Boscan oil (West Venezuela) by column chromatography. Analysis of each fraction by electron ionization mass spectrometry identified the porphyrin classes present and their carbon number ranges, but the spectra were extremely complex. Tandem mass spectrometry (MS/MS) allowed selection of molecular ions of individual carbon number porphyrins of the DPEP and etio types for fragmentation by collisionally activated dissociation. Comparison of their daughter and neutral loss spectra with those of porphyrin standards provided the first structural information on individual high-carbon-number geoporphyrins (>C/sub 33/). This information is helpful in the study of their geologic evolution and suggests the potential for using MS/MS data on high-carbon-number geoporphyrins as a parameter in oil exploration. Metalated and demetalated porphyrins of the same carbon number produced similar spectra, suggesting that samples may require less treatment for analysis by MS/MS than by conventional MS.

Johnson, J.V.; Britton, E.D.; Yost, R.A.; Quirke, J.M.E.; Cuesta, L.L.

1986-06-01T23:59:59.000Z

74

B American Society for Mass Spectrometry( 2011 DOI: 10.1007/s13361-011-0179-8  

E-Print Network (OSTI)

A new instrument that combines ion mobility spectrometry (IMS) separations with tandem mass spectrometry in the mobility dimension. Here, we report the development of a new instrument that combines mobility separations Spectrom. (2011) 22:1477Y1485 RESEARCH ARTICLE An Ion Mobility/Ion Trap/Photodissociation Instrument

Clemmer, David E.

75

Compositional Analysis of the High Molecular Weight Ethylene Oxide Propylene Oxide Copolymer by MALDI Mass Spectrometry  

E-Print Network (OSTI)

The composition of narrow distribution poly ethylene oxide-propylene oxide copolymer (Mw ~ 8700 Da) was studied using matrix assisted laser desorption ionization (MALDI) mass spectrometry. The ethylene oxide-propylene oxide copolymer produced oligomers separated by 14 Da. The average resolving power over the entire spectrum was 28,000. Approximately 448 isotopically resolved peaks representing about 56 oligomers are identified. Although agreement between experimental and calculated isotopic distributions was strong, the compositional assignment was difficult. This is due to the large number of possible isobaric components. The purpose of this research is to resolve and study the composition of high mass copolymer such as ethylene oxide-propylene oxide.

Houshia, Orwa Jaber

2012-01-01T23:59:59.000Z

76

Modern Methods for Lipid AnalysisChapter 11 Analysis of Steroids by Liquid Chromatography — Atmospheric Pressure Photoionization Mass Spectrometry  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 11 Analysis of Steroids by Liquid Chromatography — Atmospheric Pressure Photoionization Mass Spectrometry Methods and Analyses eChapters Methods - Analyses Books 7B3610598EB68717295AAD02DBA4F828

77

Modern Methods for Lipid AnalysisChapter 4 Liquid Chromatography/Electrospray Ionization Mass Spectrometry for Analysis of Oxidized Lipids  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 4 Liquid Chromatography/Electrospray Ionization Mass Spectrometry for Analysis of Oxidized Lipids Methods and Analyses eChapters Methods - Analyses Books AOCS Press Downloadable pd

78

Modern Methods for Lipid AnalysisChapter 13 Dual Parallel Liquid Chromatography/Mass Spectrometry for Lipid Analysis  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 13 Dual Parallel Liquid Chromatography/Mass Spectrometry for Lipid Analysis Methods and Analyses eChapters Methods - Analyses Books AOCS Press Downloadable pdf of Chapter

79

Extreme Chromatography: Faster, Hotter, SmallerChapter 8 Multiple Parallel Mass Spectrometry Techniques for Lipid and Vitamin D Analysis  

Science Conference Proceedings (OSTI)

Extreme Chromatography: Faster, Hotter, Smaller Chapter 8 Multiple Parallel Mass Spectrometry Techniques for Lipid and Vitamin D Analysis Methods and Analyses eChapters Methods - Analyses Books AOCS Press Downloadable pdf...

80

Development of New Soft Ionization Mass Spectrometry Approaches for Spatial Imaging of Complex Chemical and Biological Systems  

E-Print Network (OSTI)

Chemical and Biological Systems Research Team: Julia Laskin, Ljiljana Pasa-Toli, Brandi Heath, Ingela Laskin (PNNL) Purpose Multimodal chemical characterization of microbial biofilms focused bacterial colonies Develop novel mass spectrometry-based chemical imaging capabilities broadly applicable

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Advances in Conjugated Linoleic Acid Research, Vol 2Chapter 2 Gas Chromatography - Mass Spectrometry of Conjugated Linoleic Acids and Metabolites  

Science Conference Proceedings (OSTI)

Advances in Conjugated Linoleic Acid Research, Vol 2 Chapter 2 Gas Chromatography - Mass Spectrometry of Conjugated Linoleic Acids and Metabolites Health Nutrition Biochemistry eChapters Health - Nutrition - Biochemistry Dow

82

Differential Mobility Spectrometry/Mass Spectrometry: The Design of a New Mass Spectrometer for Real-Time Chemical Analysis in the Field  

SciTech Connect

The design of a prototype, field-portable mass spectrometer (MS) is described. The MS has been designed with an atmospheric interface in order to couple the system to a commercially available differential mobility spectrometer. The differential mobility spectrometer provides selective injection of trace-level analytes of interest into the inlet of the MS for real-time chemical detection. To accomplish this task, the MS design incorporates the use of an electrodynamic ion funnel to transport the ion beam, generated at atmospheric pressure, to the high-vacuum chamber that houses the mass analyzer. This leads to a design that utilizes two stages of differential pumping to achieve an overall pressure drop from atmosphere (760 Torr) to approximately 1 ×

,

2010-08-01T23:59:59.000Z

83

Characterization of Individual Nanoparticles and Applications of Nanoparticles in Mass Spectrometry  

E-Print Network (OSTI)

The chemical characterization of individual nanoparticles (NPs) mass spectrometry (SIMS) technique are Au4004+ and C60+. The ionized ejecta from each impact are recorded individually which allows to identify ions emitted from a surface volume of ~10 nm in diameter and 5-10 nm in depth. The mode of analyzing ejecta individually from each single cluster impact gives insight into surface homogeneity, in our case NPs and their immediate surroundings. We show that when the NPs (50 nm Al) are larger than the size of the volume perturbed by the projectile, the secondary ion emission (SI) resembles that of a bulk surface. However, when the NP (5 nm Ag) is of the size range of the volume perturbed by projectile the SI emission is different from that of a bulk surface. As part of this sub-assay volume study, the influence of neighboring NP on the SI emission was examined by using a mixture of different types of NPs (5 nm Au and 5 nm Ag). The methodology of using cluster SIMS via a sequence of stochastic single impacts yield information on the surface coverage of the NPs, as well as the influence of the chemical environment on the type of SI emission. We also present a case of soft landing NPs for laser desorption ionization mass spectrometry. NPs enhance the SI emission in a manner that maintains the integrity of the spatial distribution of molecular species. The results indicate that the application can be extended to imaging mass spectrometry.

Rajagopal Achary, Sidhartha Raja

2010-05-01T23:59:59.000Z

84

Analytical Validation of Accelerator Mass Spectrometry for Pharmaceutical Development: the Measurement of Carbon-14 Isotope Ratio.  

SciTech Connect

Accelerator mass spectrometry (AMS) is an isotope based measurement technology that utilizes carbon-14 labeled compounds in the pharmaceutical development process to measure compounds at very low concentrations, empowers microdosing as an investigational tool, and extends the utility of {sup 14}C labeled compounds to dramatically lower levels. It is a form of isotope ratio mass spectrometry that can provide either measurements of total compound equivalents or, when coupled to separation technology such as chromatography, quantitation of specific compounds. The properties of AMS as a measurement technique are investigated here, and the parameters of method validation are shown. AMS, independent of any separation technique to which it may be coupled, is shown to be accurate, linear, precise, and robust. As the sensitivity and universality of AMS is constantly being explored and expanded, this work underpins many areas of pharmaceutical development including drug metabolism as well as absorption, distribution and excretion of pharmaceutical compounds as a fundamental step in drug development. The validation parameters for pharmaceutical analyses were examined for the accelerator mass spectrometry measurement of {sup 14}C/C ratio, independent of chemical separation procedures. The isotope ratio measurement was specific (owing to the {sup 14}C label), stable across samples storage conditions for at least one year, linear over 4 orders of magnitude with an analytical range from one tenth Modern to at least 2000 Modern (instrument specific). Further, accuracy was excellent between 1 and 3 percent while precision expressed as coefficient of variation is between 1 and 6% determined primarily by radiocarbon content and the time spent analyzing a sample. Sensitivity, expressed as LOD and LLOQ was 1 and 10 attomoles of carbon-14 (which can be expressed as compound equivalents) and for a typical small molecule labeled at 10% incorporated with {sup 14}C corresponds to 30 fg equivalents. AMS provides an sensitive, accurate and precise method of measuring drug compounds in biological matrices.

Keck, B D; Ognibene, T; Vogel, J S

2010-02-05T23:59:59.000Z

85

230Th-234U Age-Dating Uranium by Mass Spectrometry  

Science Conference Proceedings (OSTI)

This is the standard operating procedure used by the Isotope Ratio Mass Spectrometry Group of the Chemical Sciences Division at LLNL for the preparation of a sample of uranium oxide or uranium metal for {sup 230}Th-{sup 234}U age-dating. The method described here includes the dissolution of a sample of uranium oxide or uranium metal, preparation of a secondary dilution, spiking of separate aliquots for uranium and thorium isotope dilution measurements, and purification of uranium and thorium aliquots for mass spectrometry. This SOP may be applied to uranium samples of unknown purity as in a nuclear forensic investigation, and also to well-characterized samples such as, for example, U{sub 3}O{sub 8} and U-metal certified reference materials. The sample of uranium is transferred to a quartz or PFA vial, concentrated nitric acid is added and the sample is heated on a hotplate at approximately 100 C for several hours until it dissolves. The sample solution is diluted with water to make the solution approximately 4 M HNO{sub 3} and hydrofluoric acid is added to make it 0.05 M HF. A secondary dilution of the primary uranium solution is prepared. Separate aliquots for uranium and thorium isotope dilution measurements are taken and spiked with {sup 233}U and {sup 229}Th, respectively. The spiked aliquot for uranium isotope dilution analysis is purified using EiChrom UTEVA resin. The spiked aliquot for thorium isotope dilution analysis is purified by, first, a 1.8 mL AG1x8 resin bed in 9 M HCl on which U adsorbs and Th passes through; second, adsorbing Th on a 1 mL AG1x8 resin bed in 8 M HNO{sub 3} and then eluting it with 9 M HCl followed by 0.1 M HCl + 0.005 M HF; and third, by passing the Th through a final 1.0 mL AG1x8 resin bed in 9 M HCl. The mass spectrometry is performed using the procedure 'Th and U Mass Spectrometry for {sup 230}Th-{sup 234}U Age Dating'.

Williams, R W; Gaffney, A M

2012-04-18T23:59:59.000Z

86

Time-resolved studies of particle effects in laser ablation inductively coupled plasma-mass spectrometry  

Science Conference Proceedings (OSTI)

Time resolved signals in laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) are studied to determine the influence of experimental parameters on ICP-induced fractionation effects. Differences in sample composition and morphology, i.e., ablating brass, glass, or dust pellets, have a profound effect on the time resolved signal. Helium transport gas significantly decreases large positive signal spikes arising from large particles in the ICP. A binder for pellets also reduces the abundance and amplitude of spikes in the signal. MO{sup +} ions also yield signal spikes, but these MO{sup +} spikes generally occur at different times from their atomic ion counterparts.

Perdian, D.; Bajic, S.; Baldwin, D.; Houk, R.

2007-11-13T23:59:59.000Z

87

Coal liquefaction process streams characterization and evaluation. Characterization of coal-derived materials by field desorption mass spectrometry, two-dimensional nuclear magnetic resonance, supercritical fluid extraction, and supercritical fluid chromatography/mass spectrometry  

SciTech Connect

Under contract from the DOE , and in association with CONSOL Inc., Battelle, Pacific Northwest Laboratory (PNL) evaluated four principal and several complementary techniques for the analysis of non-distillable direct coal liquefaction materials in support of process development. Field desorption mass spectrometry (FDMS) and nuclear magnetic resonance (NMR) spectroscopic methods were examined for potential usefulness as techniques to elucidate the chemical structure of residual (nondistillable) direct coal liquefaction derived materials. Supercritical fluid extraction (SFE) and supercritical fluid chromatography/mass spectrometry (SFC/MS) were evaluated for effectiveness in compound-class separation and identification of residual materials. Liquid chromatography (including microcolumn) separation techniques, gas chromatography/mass spectrometry (GC/MS), mass spectrometry/mass spectrometry (MS/MS), and GC/Fourier transform infrared (FTIR) spectroscopy methods were applied to supercritical fluid extracts. The full report authored by the PNL researchers is presented here. The following assessment briefly highlights the major findings of the project, and evaluates the potential of the methods for application to coal liquefaction materials. These results will be incorporated by CONSOL into a general overview of the application of novel analytical techniques to coal-derived materials at the conclusion of CONSOL`s contract.

Campbell, J.A.; Linehan, J.C.; Robins, W.H. [Battelle Pacific Northwest Lab., Richland, WA (United States)

1992-07-01T23:59:59.000Z

88

In situ mass spectrometry in a 10 Torr W chemical vapor deposition process for film thickness metrology  

E-Print Network (OSTI)

widely implemented using in situ sensors, par- ticularly using mass spectrometry or residual gas analysis-process ex situ film weight measurement, provided a working metrology model such that real-time mass spec- cess chemistry, temperature regime, and low-pressure sub- Torr operation of the reactor. Our analysis

Rubloff, Gary W.

89

Molecular Characterization of Nitrogen Containing Organic Compounds in Biomass Burning Aerosols Using High Resolution Mass Spectrometry  

DOE Green Energy (OSTI)

Although nitrogen-containing organic compounds (NOC) are important components of atmospheric aerosols, little is known about their chemical compositions. Here we present detailed characterization of the NOC constituents of biomass burning aerosol (BBA) samples using high resolution electrospray ionization mass spectrometry (ESI/MS). Accurate mass measurements combined with MS/MS fragmentation experiments of selected ions were used to assign molecular structures to individual NOC species. Our results indicate that N-heterocyclic alkaloid compounds - species naturally produced by plants and living organisms - comprise a substantial fraction of NOC in BBA samples collected from test burns of five biomass fuels. High abundance of alkaloids in test burns of ponderosa pine - a widespread tree in the western U.S. areas frequently affected by large scale fires - suggests that N-heterocyclic alkaloids in BBA can play a significant role in dry and wet deposition of fixed nitrogen in this region.

Laskin, Alexander; Smith, Jeffrey S.; Laskin, Julia

2009-05-13T23:59:59.000Z

90

Study of Electrochemical Reactions Using Nanospray Desorption Electrospray Ionization Mass Spectrometry  

Science Conference Proceedings (OSTI)

The combination of electrochemistry (EC) and mass spectrometry (MS) is a powerful analytical tool for studying mechanisms of redox reactions, identification of products and intermediates, and online derivatization/recognition of analytes. This work reports a new coupling interface for EC/MS by employing nanospray desorption electrospray ionization (nano-DESI), a recently developed ambient ionization method. We demonstrate online coupling of nano-DESI-MS with a traditional electrochemical flow cell, in which the electrolyzed solution emanating from the cell is ionized by nano-DESI for MS analysis. Furthermore, we show first coupling of nano-DESI-MS with an interdigitated array (IDA) electrode enabling chemical analysis of electrolyzed samples directly from electrode surfaces. Because of its inherent sensitivity, nano-DESI enables chemical analysis of small volumes and concentrations of sample solution. Specifically, good-quality signal of dopamine and its oxidized form, dopamine ortho-quinone, was obtained using 10 {mu}L of 1 {mu}M solution of dopamine on the IDA. Oxidation of dopamine, reduction of benzodiazepines, and electrochemical derivatization of thiol groups were used to demonstrate the performance of the technique. Our results show the potential of nano-DESI as a novel interface for electrochemical mass spectrometry research.

Liu, Pengyuan; Lanekoff, Ingela T.; Laskin, Julia; Dewald, Howard D.; Chen, Hao

2012-07-03T23:59:59.000Z

91

The Ramsey method in high-precision mass spectrometry with Penning traps: Experimental results  

E-Print Network (OSTI)

The highest precision in direct mass measurements is obtained with Penning trap mass spectrometry. Most experiments use the interconversion of the magnetron and cyclotron motional modes of the stored ion due to excitation by external radiofrequency-quadrupole fields. In this work a new excitation scheme, Ramsey's method of time-separated oscillatory fields, has been successfully tested. It has been shown to reduce significantly the uncertainty in the determination of the cyclotron frequency and thus of the ion mass of interest. The theoretical description of the ion motion excited with Ramsey's method in a Penning trap and subsequently the calculation of the resonance line shapes for different excitation times, pulse structures, and detunings of the quadrupole field has been carried out in a quantum mechanical framework and is discussed in detail in the preceding article in this journal by M. Kretzschmar. Here, the new excitation technique has been applied with the ISOLTRAP mass spectrometer at ISOLDE/CERN for mass measurements on stable as well as short-lived nuclides. The experimental resonances are in agreement with the theoretical predictions and a precision gain close to a factor of four was achieved compared to the use of the conventional excitation technique.

S. George; K. Blaum; F. Herfurth; A. Herlert; M. Kretzschmar; S. Nagy; S. Schwarz; L. Schweikhard; C. Yazidjian

2007-01-22T23:59:59.000Z

92

Laser Microdissection and Atmospheric Pressure Chemical Ionization Mass Spectrometry Coupled for Multimodal Imaging  

SciTech Connect

This paper describes the coupling of ambient laser ablation surface sampling, accomplished using a laser capture microdissection system, with atmospheric pressure chemical ionization mass spectrometry for high spatial resolution multimodal imaging. A commercial laser capture microdissection system was placed in close proximity to a modified ion source of a mass spectrometer designed to allow for sampling of laser ablated material via a transfer tube directly into the ionization region. Rhodamine 6G dye of red sharpie ink in a laser etched pattern as well as cholesterol and phosphatidylcholine in a cerebellum mouse brain thin tissue section were identified and imaged from full scan mass spectra. A minimal spot diameter of 8 m was achieved using the 10X microscope cutting objective with a lateral oversampling pixel resolution of about 3.7 m. Distinguishing between features approximately 13 m apart in a cerebellum mouse brain thin tissue section was demonstrated in a multimodal fashion including co-registered optical and mass spectral chemical images.

Lorenz, Matthias [ORNL; Ovchinnikova, Olga S [ORNL; Kertesz, Vilmos [ORNL; Van Berkel, Gary J [ORNL

2013-01-01T23:59:59.000Z

93

A study of the formation of cluster ions from metal acetates using plasma desorption mass spectrometry  

E-Print Network (OSTI)

A novel application of desorption/ionization methods of mass spectrometry, e. g. plasma desorption mass spectrometry (PDMS), is the analysis of both the composition and structure of solid materials in one experiment. Cluster ions emitted from the impact of a 252Cf fission fragment on a surface may represent a "view" of the solid construction over atomic distances if composed of atoms from adjacent sites in the surface. A clearer understanding of the mechanism of secondary cluster ion formation is necessary to evaluate the usefulness of PDMS as a surface characterization technique. The aim of this research was to use metal acetate samples to study secondary cluster ion formation in PDMS. In two sets of experiments, metal acetates from period IV and group IIB of the periodic table were used to measure the influence on cluster formation by the ground state electronic configuration and the ionic size, respectively, of the metal constituent. Relative yields for homologous negative and positive secondary cluster ions were determined and compared to thermochemical properties of the metal ion or the metal acetate molecule (AHf and lattice energy). Secondary ions in negative PDMS mass spectra attributable to a gas phase recombination formation mechanism follow trends predicted by these thermochemical properties. Another series of cluster ions, however, with the composition [M(Ac)2]Ac-(where Ac = acetate) does not follow the same trends, indicating possible formation via intact emission from the solid surface. Positive secondary cluster ions showed differences from the negative ions both in the relative yield distribution and the types of ions observed. Positive cluster ions from metal acetates from the fourth period of the periodic table were mainly metal oxides. On the other hand, positive clusters ions from the group IIB of the periodic table were mainly mirror images of the negative spectra. These differences suggest that the bonding characteristics of the metal ion play an important role in the secondary cluster ion formation process.

Mendez Silvagnoli, Winston Reinaldo

1995-01-01T23:59:59.000Z

94

LC-IMS-MS Feature Finder: Detecting Multidimensional Liquid Chromatography, Ion Mobility, and Mass Spectrometry Features in Complex Datasets  

SciTech Connect

We introduce a command line software application LC-IMS-MS Feature Finder that searches for molecular ion signatures in multidimensional liquid chromatography-ion mobility spectrometry-mass spectrometry (LC-IMS-MS) data by clustering deisotoped peaks with similar monoisotopic mass, charge state, LC elution time, and ion mobility drift time values. The software application includes an algorithm for detecting and quantifying co-eluting chemical species, including species that exist in multiple conformations that may have been separated in the IMS dimension.

Crowell, Kevin L.; Slysz, Gordon W.; Baker, Erin Shammel; Lamarche, Brian L.; Monroe, Matthew E.; Ibrahim, Yehia M.; Payne, Samuel H.; Anderson, Gordon A.; Smith, Richard D.

2013-09-13T23:59:59.000Z

95

Analysis of fission gas release kinetics by on-line mass spectrometry  

SciTech Connect

The release of fission gas (Xe and Kr) and helium out of nuclear fuel materials in normal operation of a nuclear power reactor can constitute a strong limitation of the fuel lifetime. Moreover, radioactive isotopes of Xe and Kr contribute significantly to the global radiological source term released in the primary coolant circuit in case of accidental situations accompanied by fuel rod loss of integrity. As a consequence, fission gas release investigation is of prime importance for the nuclear fuel cycle economy, and is the driven force of numerous R and D programs. In this domain, for solving current fuel behavior understanding issues, preparing the development of new fuels (e.g. for Gen IV power systems) and for improving the modeling prediction capability, there is a marked need for innovations in the instrumentation field, mainly for: . Quantification of very low fission gas concentrations, released from fuel sample and routed in sweeping lines. Monitoring of quick gas release variations by quantification of elementary release during a short period of time. Detection of a large range of atomic masses (e.g. H{sub 2}, HT, He, CO, CO{sub 2}, Ne, Ar, Kr, Xe), together with a performing separation of isotopes for Xe and Kr elements. Coupling measurement of stable and radioactive gas isotopes, by using in parallel mass spectrometry and gamma spectrometry techniques. To fulfill these challenging needs, a common strategy for analysis equipment implementation has been set up thanks to a recently launched collaboration between the CEA and the Univ. of Provence, with the technological support of the Liverpool Univ.. It aims at developing a chronological series of mass spectrometer devices based upon mass filter and 2D/3D ion traps with Fourier transform operating mode and having increasing levels of performances to match the previous challenges for out-of pile and in-pile experiments. The final objective is to install a high performance online mass spectrometer coupled to a gamma spectrometer in the fission product laboratory of the future Jules Horowitz Material Test Reactor. An intermediate step will consist of testing first equipment on an existing experimental facility in the LECA-STAR Hot Cell Laboratory of the CEA Cadarache. This paper presents the scientific and operational stakes linked to fission gas issues, resumes the current state of art for analyzing them in nuclear facilities, then presents the skills gathered through this collaboration to overcome technological bottlenecks. Finally it describes the implementation strategy in nuclear research facilities of the CEA Cadarache. (authors)

Zerega, Y.; Reynard-Carette, C. [Univ. of Provence, Laboratoire Chimie Provence, UMR 6264, Avenue escadrille Normandie - Niemen, F-13397 Marseille (France); Parrat, D. [CEA, Nuclear Energy Div. DEN, CEA Cadarache, F-13108 Saint-Paul-lez-Durance (France); Carette, M. [Univ. of Provence, Laboratoire Chimie Provence, UMR 6264, Avenue escadrille Normandie - Niemen, F-13397 Marseille (France); Brkic, B. [Univ. of Liverpool, Dept. of Electrical Engineering and Electronics, Liverpool L69 3BX (United Kingdom); Lyoussi, A.; Bignan, G. [CEA, Nuclear Energy Div. DEN, CEA Cadarache, F-13108 Saint-Paul-lez-Durance (France); Janulyte, A.; Andre, J. [Univ. of Provence, Laboratoire Chimie Provence, UMR 6264, Avenue escadrille Normandie - Niemen, F-13397 Marseille (France); Pontillon, Y.; Ducros, G. [CEA, Nuclear Energy Div. DEN, CEA Cadarache, F-13108 Saint-Paul-lez-Durance (France); Taylor, S. [Univ. of Liverpool, Dept. of Electrical Engineering and Electronics, Liverpool L69 3BX (United Kingdom)

2011-07-01T23:59:59.000Z

96

MAINTAINING HIGH RESOLUTION MASS SPECTROMETRY CAPABILITIES FOR NATIONAL NUCLEAR SECURITY ADMINISTRATION APPLICATIONS  

SciTech Connect

The Department of Energy (DOE) National Nuclear Security Administration (NNSA) has a specialized need for analyzing low mass gas species at very high resolutions. The currently preferred analytical method is electromagnetic sector mass spectrometry. This method allows the NNSA Nuclear Security Enterprise (NSE) to resolve species of similar masses down to acceptable minimum detection limits (MDLs). Some examples of these similar masses are helium-4/deuterium and carbon monoxide/nitrogen. Through the 1980s and 1990s, there were two vendors who supplied and supported these instruments. However, with declining procurements and down turns in the economy, the supply of instruments, service and spare parts from these vendors has become less available, and in some cases, nonexistent. The largest NSE user of this capability is the Savannah River Site (SRS), located near Aiken, South Carolina. The Research and Development Engineering (R&DE) Group in the Savannah River National Laboratory (SRNL) investigated the areas of instrument support that were needed to extend the life cycle of these aging instruments. Their conclusions, as to the focus areas of electromagnetic sector mass spectrometers to address, in order of priority, were electronics, software and hardware. Over the past 3-5 years, the R&DE Group has designed state of the art electronics and software that will allow high resolution legacy mass spectrometers, critical to the NNSA mission, to be operated for the foreseeable future. The funding support for this effort has been from several sources, including the SRS Defense Programs, NNSA Readiness Campaign, Pantex Plant and Sandia National Laboratory. To date, electronics systems have been upgraded on one development system at SRNL, two production systems at Pantex and one production system at Sandia National Laboratory. An NSE working group meets periodically to review strategies going forward. The R&DE Group has also applied their work to the electronics for a Thermal Ionization Mass Spectrometer (TIMS) instrument, which applies a similar mass spectrometric technology for resolving high mass isotopes, such as plutonium and uranium. Due to non-compete clauses for DOE, all work has been performed and applied to instruments which are obsolete and are no longer supported by the original vendor.

Wyrick, S.; Cordaro, J.; Reeves, G.; Mcintosh, J.; Mauldin, C.; Tietze, K.; Varble, D.

2011-06-06T23:59:59.000Z

97

Final Report - Advanced Ion Trap Mass Spectrometry Program - Oak Ridge National Laboratory - Sandia National Laboratory  

Science Conference Proceedings (OSTI)

This report covers the three main projects that collectively comprised the Advanced Ion Trap Mass Spectrometry Program. Chapter 1 describes the direct interrogation of individual particles by laser desorption within the ion trap mass spectrometer analyzer. The goals were (1) to develop an ''intelligent trigger'' capable of distinguishing particles of biological origin from those of nonbiological origin in the background and interferent particles and (2) to explore the capability for individual particle identification. Direct interrogation of particles by laser ablation and ion trap mass spectrometry was shown to have good promise for discriminating between particles of biological origin and those of nonbiological origin, although detailed protocols and operating conditions were not worked out. A library of more than 20,000 spectra of various types of biological particles has been assembled. Methods based on multivariate analysis and on neural networks were used to discriminate between particles of biological origin and those of nonbiological origin. It was possible to discriminate between at least some species of bacteria if mass spectra of several hundred similar particles were obtained. Chapter 2 addresses the development of a new ion trap mass analyzer geometry that offers the potential for a significant increase in ion storage capacity for a given set of analyzer operating conditions. This geometry may lead to the development of smaller, lower-power field-portable ion trap mass spectrometers while retaining laboratory-scale analytical performance. A novel ion trap mass spectrometer based on toroidal ion storage geometry has been developed. The analyzer geometry is based on the edge rotation of a quadrupolar ion trap cross section into the shape of a torus. Initial performance of this device was poor, however, due to the significant contribution of nonlinear fields introduced by the rotation of the symmetric ion-trapping geometry. These nonlinear resonances contributed to poor mass resolution and sensitivity and to erratic ion ejection behavior. To correct for these nonlinear effects, the geometry of the toroid ion trap analyzer has been modified to create an asymmetric torus, as first suggested by computer simulations that predicted significantly improved performance and unit mass resolution for this geometry. A reduced-sized version (one-fifth scale) has been fabricated but was not tested within the scope of this project. Chapter 3 describes groundbreaking progress toward the use of ion-ion chemistry to control the charge state of ions formed by the electrospray ionization process, which in turn enables precision analysis of whole proteins. In addition, this technique may offer the unique possibility of a priori identification of unknown biological material when employed with existing proteomics and genomic databases. Ion-ion chemistry within the ion trap was used to reduce the ions in highly charged states to states of +1 and +2 charges. Reduction in charge greatly simplifies identification of molecular weights of fragments from large biological molecules. This technique enables the analysis of whole proteins as biomarkers for the detection and identification of all three classes of biological weapons (bacteria, toxins, and viruses). In addition to methods development, tests were carried out with samples of tap water, local creek water, and soil (local red clay) spiked with melittin (bee venom), cholera toxin, and virus MS2. All three analytes were identified in tap water and soil; however, all three were problematic for detection in creek water at concentrations of 1 nM. More development of methods is needed.

Whitten, W.B.

2002-12-18T23:59:59.000Z

98

Modern Methods for Lipid AnalysisChapter 8 Analysis of Carotenoids Using Atmospheric Pressure Chemical Ionization Mass Spectrometry  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 8 Analysis of Carotenoids Using Atmospheric Pressure Chemical Ionization Mass Spectrometry Methods and Analyses eChapters Methods - Analyses Books AOCS Press 634F787D8F694E5A50C242671C4B87C5

99

Assessment of Non-traditional Isotopic Ratios by Mass Spectrometry for Analysis of Nuclear Activities: Annual Report Year 2  

Science Conference Proceedings (OSTI)

The objective of this work is to identify isotopic ratios suitable for analysis via mass spectrometry that distinguish between commercial nuclear reactor fuel cycles, fuel cycles for weapons grade plutonium, and products from nuclear weapons explosions. Methods will also be determined to distinguish the above from medical and industrial radionuclide sources. Mass spectrometry systems will be identified that are suitable for field measurement of such isotopes in an expedient manner. Significant progress has been made with this project within the past year: (1) Isotope production from commercial nuclear fuel cycles and nuclear weapons fuel cycles have been modeled with the ORIGEN and MCNPX codes. (2) MCNPX has been utilized to calculate isotopic inventories produced in a short burst fast bare sphere reactor (to approximate the signature of a nuclear weapon). (3) Isotopic ratios have been identified that are good for distinguishing between commercial and military fuel cycles as well as between nuclear weapons and commercial nuclear fuel cycles. (4) Mass spectrometry systems have been assessed for analysis of the fission products of interest. (5) A short-list of forensic ratios have been identified that are well suited for use in portable mass spectrometry systems.

Biegalski, S; Buchholz, B

2009-08-26T23:59:59.000Z

100

ESI/Ion Trap/Ion Mobility/Time-of-Flight Mass Spectrometry for Rapid and Sensitive Analysis of  

E-Print Network (OSTI)

discuss a new separation strategy for biomolecules that is based on differences in ion mobilitiesESI/Ion Trap/Ion Mobility/Time-of-Flight Mass Spectrometry for Rapid and Sensitive Analysis* Department of Chemistry, Indiana University, Bloomington, Indiana 47405 An ion trap/ion mobility

Clemmer, David E.

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101

Studies of selenium and xenon in inductively coupled plasma mass spectrometry  

SciTech Connect

Since its development, inductively coupled plasma mass spectrometry (ICP-MS) has been a widely used analytical technique. ICP-MS offers low detection limits, easy determination of isotope ratios, and simple mass spectra from analyte elements. ICP-MS has been successfully employed for many applications including geological, environmental, biological, metallurgical, food, medical, and industrial. One specific application important to many areas of study involves elemental speciation by using ICP-MS as an element specific detector interfaced to liquid chromatography. Elemental speciation information is important and cannot be obtained by atomic spectrometric methods alone which measure only the total concentration of the element present. Part 1 of this study describes the speciation of selenium in human serum by size exclusion chromatography (SEC) and detection by ICP-MS. Although ICP-MS has been widely sued, room for improvement still exists. Difficulties in ICP-MS include noise in the background, matrix effects, clogging of the sampling orifice with deposited solids, and spectral interference caused by polyatomic ions. Previous work has shown that the addition of xenon into the central channel of the ICP decreases polyatomic ion levels. In Part 2 of this work, a fundamental study involving the measurement of the excitation temperature is carried out to further understand xenon`s role in the reduction of polyatomic ions. 155 refs.

Bricker, T.

1994-07-27T23:59:59.000Z

102

An Automated Platform for High-Resolution Tissue Imaging Using Nanospray Desorption Electrospray Ionization Mass Spectrometry  

SciTech Connect

An automated platform has been developed for acquisition and visualization of mass spectrometry imaging (MSI) data using nanospray desorption electrospray ionization (nano-DESI). The new system enables robust operation of the nano-DESI imaging source over many hours. This is achieved by controlling the distance between the sample and the probe by mounting the sample holder onto an automated XYZ stage and defining the tilt of the sample plane. This approach is useful for imaging of relatively flat samples such as thin tissue sections. Custom software called MSI QuickView was developed for visualization of large data sets generated in imaging experiments. MSI QuickView enables fast visualization of the imaging data during data acquisition and detailed processing after the entire image is acquired. The performance of the system is demonstrated by imaging rat brain tissue sections. High resolution mass analysis combined with MS/MS experiments enabled identification of lipids and metabolites in the tissue section. In addition, high dynamic range and sensitivity of the technique allowed us to generate ion images of low-abundance isobaric lipids. High-spatial resolution image acquired over a small region of the tissue section revealed the spatial distribution of an abundant brain metabolite, creatine, in the white and gray matter that is consistent with the literature data obtained using magnetic resonance spectroscopy.

Lanekoff, Ingela T.; Heath, Brandi S.; Liyu, Andrey V.; Thomas, Mathew; Carson, James P.; Laskin, Julia

2012-10-02T23:59:59.000Z

103

Molecular Characterization of Biomass Burning Aerosols Using High Resolution Mass Spectrometry  

DOE Green Energy (OSTI)

Chemical characterizations of atmospheric aerosols is a serious analytical challenge because of the complexity of particulate matter analyte composed of a large number of compounds with a wide range of molecular structures, physico-chemical properties, and reactivity. In this study chemical composition of biomass burning organic aerosol (BBOA) samples is characterized by high resolution electrospray ionization mass spectrometry (ESI/MS). Accurate mass measurement combined with Kendrick analysis allowed us to assign elemental composition for hundreds of compounds in the range of m/z values of 50-1000. ESI/MS spectra of different BBOA samples contain a variety of distinct, sample specific, characteristic peaks that can be used as unique markers for different types of biofuels. Our results indicate that a significant number of high-MW organic compounds in BBOA samples are highly oxidized polar species that can be efficiently detected using ESI/MS but are difficult to observe using the conventional GCMS analysis of aerosol samples. The average O:C ratios obtained for each of the BBOA samples studied in this work are in a strikingly good agreement with the previously reported values obtained using STXM/NEXAFS. The degree of unsaturation of detected organic compounds shows a clear decrease with increase in the molecular weight of the anyalyte molecules. The decrease is particularly pronounced for the samples containing a large number of CH2-based homologous series.

Smith, Jeffrey S.; Laskin, Alexander; Laskin, Julia

2009-02-13T23:59:59.000Z

104

Multivariate analysis of progressive thermal desorption coupled gas chromatography-mass spectrometry.  

SciTech Connect

Thermal decomposition of poly dimethyl siloxane compounds, Sylgard{reg_sign} 184 and 186, were examined using thermal desorption coupled gas chromatography-mass spectrometry (TD/GC-MS) and multivariate analysis. This work describes a method of producing multiway data using a stepped thermal desorption. The technique involves sequentially heating a sample of the material of interest with subsequent analysis in a commercial GC/MS system. The decomposition chromatograms were analyzed using multivariate analysis tools including principal component analysis (PCA), factor rotation employing the varimax criterion, and multivariate curve resolution. The results of the analysis show seven components related to offgassing of various fractions of siloxanes that vary as a function of temperature. Thermal desorption coupled with gas chromatography-mass spectrometry (TD/GC-MS) is a powerful analytical technique for analyzing chemical mixtures. It has great potential in numerous analytic areas including materials analysis, sports medicine, in the detection of designer drugs; and biological research for metabolomics. Data analysis is complicated, far from automated and can result in high false positive or false negative rates. We have demonstrated a step-wise TD/GC-MS technique that removes more volatile compounds from a sample before extracting the less volatile compounds. This creates an additional dimension of separation before the GC column, while simultaneously generating three-way data. Sandia's proven multivariate analysis methods, when applied to these data, have several advantages over current commercial options. It also has demonstrated potential for success in finding and enabling identification of trace compounds. Several challenges remain, however, including understanding the sources of noise in the data, outlier detection, improving the data pretreatment and analysis methods, developing a software tool for ease of use by the chemist, and demonstrating our belief that this multivariate analysis will enable superior differentiation capabilities. In addition, noise and system artifacts challenge the analysis of GC-MS data collected on lower cost equipment, ubiquitous in commercial laboratories. This research has the potential to affect many areas of analytical chemistry including materials analysis, medical testing, and environmental surveillance. It could also provide a method to measure adsorption parameters for chemical interactions on various surfaces by measuring desorption as a function of temperature for mixtures. We have presented results of a novel method for examining offgas products of a common PDMS material. Our method involves utilizing a stepped TD/GC-MS data acquisition scheme that may be almost totally automated, coupled with multivariate analysis schemes. This method of data generation and analysis can be applied to a number of materials aging and thermal degradation studies.

Van Benthem, Mark Hilary; Mowry, Curtis Dale; Kotula, Paul Gabriel; Borek, Theodore Thaddeus, III

2010-09-01T23:59:59.000Z

105

Accelerator Mass Spectrometry Measurements of Plutonium in Sediment and Seawater from the Marshall Islands  

Science Conference Proceedings (OSTI)

During the summer 2000, I was given the opportunity to work for about three months as a technical trainee at Lawrence Livermore National Laboratory, or LLNL as I will refer to it hereafter. University of California runs this Department of Energy laboratory, which is located 70 km east of San Francisco, in the small city of Livermore. This master thesis in Radioecology is based on the work I did here. LLNL, as a second U.S.-facility for development of nuclear weapons, was built in Livermore in the beginning of the 1950's (Los Alamos in New Mexico was the other one). It has since then also become a 'science center' for a number of areas like magnetic and laser fusion energy, non-nuclear energy, biomedicine, and environmental science. The Laboratory's mission has changed over the years to meet new national needs. The following two statements were found on the homepage of LLNL (http://www.llnl.gov), at 2001-03-05, where also information about the laboratory and the scientific projects that takes place there, can be found. 'Our primary mission is to ensure that the nation's nuclear weapons remain safe, secure, and reliable and to prevent the spread and use of nuclear weapons worldwide'. 'Our goal is to apply the best science and technology to enhance the security and well-being of the nation and to make the world a safer place.' The Marshall Islands Dose Assessment and Radioecology group at the Health and Ecological Assessments division employed me, and I also worked to some extent with the Centre for Accelerator Mass Spectrometry (CAMS) group. The work I did at LLNL can be divided into two parts. In the first part Plutonium (Pu) measurements in sediments from the Rongelap atoll in Marshall Islands, using Accelerator Mass Spectrometry (AMS) were done. The method for measuring these kinds of samples is well understood at LLNL since soil samples have been measured with AMS for Pu in the past. Therefore it was the results that were of main interest and not the technique. The second part was to take advantage of AMS's very high sensitivity by measure the Pu-concentrations in small volumes (0.04-1 L) of seawater. The technique for using AMS at Pu-measurements in seawater is relatively new and the main task for me was to find out a method that could work in practice. The area where the sediment samples and the water samples were collected are high above background levels for many radionuclides, including Pu, because of the detonation of the nuclear bomb code-named Castle Bravo, in 1954.

Leisvik, M; Hamilton, T

2001-08-01T23:59:59.000Z

106

Facilities: NHMFL 14.5 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Citation: A Pseudoatomic Model of the COPII Cage Obtained from Cryo-Electron Microscopy and Mass Spectrometry,  

E-Print Network (OSTI)

Facilities: NHMFL 14.5 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Citation ultrahigh-resolution 14.5 tesla Fourier transform ion cyclotron resonance mass spectrometry. The Mag

Weston, Ken

107

Comparative proteogenomics: combining mass spectrometry and comparative genomics to analyze multiple genomes  

SciTech Connect

While bacterial genome annotations have significantly improved in recent years, techniques for bacterial proteome annotation (including post-translational chemical modifications, signal peptides, proteolytic events, etc.) are still in their infancy. At the same time, the number of sequenced bacterial genomes is rising sharply, far outpacing our ability to validate the predicted genes, let alone annotate bacterial proteomes. In this study, we use tandem mass spectrometry (MS/MS) to annotate the proteome of Shewanella oneidensis MR-1, an important microbe for bioremediation. In particular, we provide the first comprehensive map of post-translational modifications in a bacterial genome, including a large number of chemical modifications, signal peptide cleavages and cleavage of N-terminal methionine residues. We also detect multiple genes that were missed or assigned incorrect start positions by gene prediction programs and suggest corrections to improve the gene annotation. This study demonstrates that complementing every genome sequencing project by an MS/MS project would significantly improve both genome and proteome annotations for a reasonable cost.

Gupta, Nitin; Benhamida, Jamal; Bhargava, Vipul; Goodman, Daniel; Kain , Elisabeth; Kerman, Ian; Nguyen , Ngan; Ollikainen, Noah; Rodriguez, Jesse; Wang, J.; Lipton, Mary S.; Romine, Margaret F.; Bafna, Vineet; Smith, Richard D.; Pevzner, Pavel A.

2008-07-30T23:59:59.000Z

108

Determination of the stellar (n,gamma) cross section of 40Ca with accelerator mass spectrometry  

E-Print Network (OSTI)

The stellar (n,gamma) cross section of 40Ca at kT=25 keV has been measured with a combination of the activation technique and accelerator mass spectrometry (AMS). This combination is required when direct off-line counting of the produced activity is compromised by the long half-life and/or missing gamma-ray transitions. The neutron activations were performed at the Karlsruhe Van de Graaff accelerator using the quasistellar neutron spectrum of kT=25 keV produced by the 7Li(p,n)7Be reaction. The subsequent AMS measurements were carried out at the Vienna Environmental Research Accelerator (VERA) with a 3 MV tandem accelerator. The doubly magic 40Ca is a bottle-neck isotope in incomplete silicon burning, and its neutron capture cross section determines the amount of leakage, thus impacting on the eventual production of iron group elements. Because of its high abundance, 40Ca can also play a secondary role as "neutron poison" for the s-process. Previous determinations of this value at stellar energies were based on time-of-flight measurements. Our method uses an independent approach, and yields for the Maxwellian-averaged cross section at kT=30 keV a value of 30 keV= 5.73+/-0.34 mb.

I. Dillmann; C. Domingo-Pardo; M. Heil; F. Käppeler; A. Wallner; O. Forstner; R. Golser; W. Kutschera; A. Priller; P. Steier; A. Mengoni; R. Gallino; M. Paul; C. Vockenhuber

2009-07-01T23:59:59.000Z

109

Imaging Nicotine in Rat Brain Tissue by Use of Nanospray Desorption Electrospray Ionization Mass Spectrometry  

SciTech Connect

Imaging mass spectrometry offers simultaneous detection of drugs, drug metabolites and endogenous substances in a single experiment. This is important when evaluating effects of a drug on a complex organ system such as the brain, where there is a need to understand how regional drug distribution impacts function. Nicotine is an addictive drug and its action in the brain is of high interest. Here we use nanospray desorption electrospray ionization, nano-DESI, imaging to discover the localization of nicotine in rat brain tissue after in vivo administration of nicotine. Nano-DESI is a new ambient technique that enables spatially-resolved analysis of tissue samples without special sample pretreatment. We demonstrate high sensitivity of nano-DESI imaging that enables detection of only 0.7 fmole nicotine per pixel in the complex brain matrix. Furthermore, by adding deuterated nicotine to the solvent, we examined how matrix effects, ion suppression, and normalization affect the observed nicotine distribution. Finally, we provide preliminary results suggesting that nicotine localizes to the hippocampal substructure called dentate gyrus.

Lanekoff, Ingela T.; Thomas, Mathew; Carson, James P.; Smith, Jordan N.; Timchalk, Charles; Laskin, Julia

2013-01-15T23:59:59.000Z

110

Combination of chemical reduction and tandem mass spectrometry for the characterization of sulfur-containing fuel constituents  

SciTech Connect

Tandem mass spectrometry has been combined with a calcium/mixed amines reduction system to characterize an SRC-II middle distillate fraction for sulfur-containing polynuclear aromatic hydrocarbons. Parent scans, which characterize a complex mixture for all components which fragment to common structural moieties, were used to identify alkyl-benzothiophenes and dibenzothiophenes as well as alkyl-benzothiophene sulfones. 15 references, 5 figures, 1 table.

Wood, K.V.; Cooks, R.G.; Laugal, J.A.; Benkeser, R.A.

1985-03-01T23:59:59.000Z

111

Chemical Analysis of Complex Organic Mixtures Using Reactive Nanospray Desorption Electrospray Ionization Mass Spectrometry  

SciTech Connect

Reactive nanospray desorption electrospray ionization (nano-DESI) combined with high-resolution mass spectrometry was utilized for the analysis of secondary organic aerosol produced through ozonolysis of limonene (LSOA). Previous studies showed that LSOA constituents are multifunctional compounds containing aldehyde and ketone groups. In this study, we used the selectivity of the Girard T (GT) reagent towards carbonyl compounds to examine the utility of reactive nano-DESI for the analysis of complex organic mixtures. In these experiments, 1-100 {micro}M GT solution was used as a working solvent for reactive nano-DESI analysis. Abundant products of a single addition of GT to LSOA constituents were observed at GT concentrations in excess of 10 {micro}M. We found that LSOA compounds with 18-20 carbon atoms (dimers) and 27-30 carbon atoms (trimers) react with GT through a simple addition reaction resulting in formation of the carbinolamine derivative. In contrast, reactions of GT with monomeric species result in formation of both the carbinolamine and the hydrazone derivatives. In addition, several monomers did not react with GT on the timescale of our experiment. These molecules were characterized by relatively high values of the double bond equivalent (DBE) and low oxygen content. Furthermore, because addition of a charged GT tag to a neutral molecule eliminates the discrimination against the low proton affinity compounds in the ionization process, reactive nano-DESI analysis enables quantification of individual compounds in the complex mixture. For example, we were able to estimate for the first time the amounts of dimers and trimers in the LSOA mixture. Specifically, we found that the most abundant LSOA dimer was detected at ca. 0.5 pg level and the total amount of dimers and trimers in the analyzed sample was just around 11 pg. Our results indicate that reactive nano-DESI is a valuable approach for examining the presence of specific functional groups and quantification of compounds possessing these groups in complex mixtures.

Laskin, Julia; Eckert, Peter A.; Roach, Patrick J.; Heath, Brandi S.; Nizkorodov, Sergey A.; Laskin, Alexander

2012-08-21T23:59:59.000Z

112

{sup 99}Tc bioassay by inductively coupled plasma mass spectrometry (ICP-MS)  

Science Conference Proceedings (OSTI)

A means of analyzing {sup 99}Tc in urine by inductively coupled plasma mass spectrometry (ICP-MS) has been developed. Historically, {sup 99}Tc analysis was based on the radiometric detection of the 293 keV E{sub Max} beta decay product by liquid scintillation or gas flow proportional counting. In a urine matrix, the analysis of{sup 99}Tc is plagued with many difficulties using conventional radiometric methods. Difficulties originate during chemical separation due to the volatile nature of Tc{sub 2}O{sub 7} or during radiation detection due to color or chemical quenching. A separation scheme for {sup 99}Tc detection by ICP-MS is given and is proven to be a sensitive and robust analytical alternative. A comparison of methods using radiometric and mass quantitation of {sup 99}Tc has been conducted in water, artificial urine, and real urine matrices at activity levels between 700 and 2,200 dpm/L. Liquid scintillation results based on an external standard quench correction and a quench curve correction method are compared to results obtained by ICP-MS. Each method produced accurate results, however the precision of the ICP-MS results is superior to that of liquid scintillation results. Limits of detection (LOD) for ICP-MS and liquid scintillation detection are 14.67 and 203.4 dpm/L, respectively, in a real urine matrix. In order to determine the basis for the increased precision of the ICP-MS results, the detection sensitivity for each method is derived and measured. The detection sensitivity for the {sup 99}Tc isotope by ICP-MS is 2.175 x 10{sup {minus}7} {+-} 8.990 x 10{sup {minus}9} and by liquid scintillation is 7.434 x 10{sup {minus}14} {+-} 7.461 x 10{sup {minus}15}. A difference by seven orders of magnitude between the two detection systems allows ICP-MS samples to be analyzed for a period of 15 s compared to 3,600 s by liquid scintillation counting with a lower LOD.

Lewis, L.A.

1998-05-01T23:59:59.000Z

113

Modern Methods for Lipid AnalysisChapter 12 Toward Total Cellular Lipidome Analysis by ESI Mass Spectrometry from a Crude Lipid Extract  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 12 Toward Total Cellular Lipidome Analysis by ESI Mass Spectrometry from a Crude Lipid Extract Methods and Analyses eChapters Methods - Analyses Books AOCS Press Downloadable pdf ...

114

Lipid Analysis and Lipidomics: New Techniques & ApplicationChapter 3 Global Cellular Lipidome Analyses by Shotgun Lipidomics Using Multidimensional Mass Spectrometry  

Science Conference Proceedings (OSTI)

Lipid Analysis and Lipidomics: New Techniques & Application Chapter 3 Global Cellular Lipidome Analyses by Shotgun Lipidomics Using Multidimensional Mass Spectrometry Methods and Analyses eChapters Methods - Analyses Books 2D17DD82D1DB9F2

115

Modern Methods for Lipid AnalysisCh 6 Regiospecific Analysis of Triacylglycerols using Hi Performance Liquid Chromatography/AtmosphericPressure Chemical Ionization Mass Spectrometry  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Ch 6 Regiospecific Analysis of Triacylglycerols using Hi Performance Liquid Chromatography/AtmosphericPressure Chemical Ionization Mass Spectrometry Methods and Analyses eChapters Methods - Analyses Books

116

Modern Methods for Lipid AnalysisChapter 2 Analysis of Phospholipids by Liquid Chromatography Coupled with Online Electrospray Ionization Mass Spectrometry  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 2 Analysis of Phospholipids by Liquid Chromatography Coupled with Online Electrospray Ionization Mass Spectrometry Methods and Analyses eChapters Methods - Analyses Books AOCS Press A76556A5B4

117

Lipid Analysis and Lipidomics: New Techniques & ApplicationChapter 2 An Overview of Modern Mass Spectrometry Methods in the Toolbox of Lipid Chemists and Biochemists  

Science Conference Proceedings (OSTI)

Lipid Analysis and Lipidomics: New Techniques & Application Chapter 2 An Overview of Modern Mass Spectrometry Methods in the Toolbox of Lipid Chemists and Biochemists Methods and Analyses eChapters Methods - Analyses Books Dow

118

Nutrition and Biochemistry of PhospholipidsChapter 9 Compositional Analysis of Complex Mixtures of Sphingolipids by Liquid Chromatography — Tandem Mass Spectrometry  

Science Conference Proceedings (OSTI)

Nutrition and Biochemistry of Phospholipids Chapter 9 Compositional Analysis of Complex Mixtures of Sphingolipids by Liquid Chromatography — Tandem Mass Spectrometry Health Nutrition Biochemistry eChapters Health - Nutrition - Biochemist

119

Modern Methods for Lipid AnalysisChapter 7 Qualitative and Quantitative Analysis of Triacylglycerolsby Atmospheric Pressure Ionization (APCI and ESI) Mass Spectrometry Techniques  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 7 Qualitative and Quantitative Analysis of Triacylglycerolsby Atmospheric Pressure Ionization (APCI and ESI) Mass Spectrometry Techniques Methods and Analyses eChapters Methods - Analyses Books AO

120

Extreme Chromatography: Faster, Hotter, SmallerChapter 6 Silver-ion High-performance Liquid Chromatography—Mass Spectrometry in the Analysis of Lipids  

Science Conference Proceedings (OSTI)

Extreme Chromatography: Faster, Hotter, Smaller Chapter 6 Silver-ion High-performance Liquid Chromatography—Mass Spectrometry in the Analysis of Lipids Methods and Analyses eChapters Methods - Analyses Books Downloadable pdf...

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121

Modern Methods for Lipid AnalysisChapter 3 Electrospray Ionization with Low-Energy Collisionally Activated Dissociation Tandem Mass Spectrometry of Complex Lipids:  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 3 Electrospray Ionization with Low-Energy Collisionally Activated Dissociation Tandem Mass Spectrometry of Complex Lipids: Methods and Analyses eChapters Methods - Analyses Books AOCS Press ...

122

Advances in Conjugated Linoleic Acid Research, Volume 3Chapter 6 Structural Characterization of CLA Methyl Esters with Acetonitrile Chemical Ionization Tandem Mass Spectrometry  

Science Conference Proceedings (OSTI)

Advances in Conjugated Linoleic Acid Research, Volume 3 Chapter 6 Structural Characterization of CLA Methyl Esters with Acetonitrile Chemical Ionization Tandem Mass Spectrometry Health Nutrition Biochemistry eChapters Health - Nutrition

123

Nano-Domain Analysis Via Massive Cluster Secondary Ion Mass Spectrometry in the Event-by-Event Mode  

E-Print Network (OSTI)

Secondary ion mass spectrometry (SIMS) is a surface analysis technique which characterizes species sputtered by an energetic particle beam. Bombardment with cluster projectiles offers the following notable advantages over bombardment with atomic ions or small clusters: enhanced emission of molecular ions, low damage cross-section, and reduced molecular fragmentation. Additionally, in the case of Au4004 and C60 impacts, desorption originates from nanometric volumes. These features make clusters useful probes to obtain molecular information from both nano-objects and nano-domains. The "event-by-event bombardment/detection mode" probes nano-objects one-at-a-time, while collecting and storing the corresponding secondary ion (SI) information. Presented here are the first experiments where free-standing nano-objects were bombarded with keV projectiles of atomic to nanoparticle size. The objects are aluminum nano-whiskers, 2 nm in diameter and ~250 nm in length. Au4004 has a diameter of ~2 nm, comparable to the nominal diameter of the nanowhiskers. There are notable differences in the SI response from sample volumes too small for full projectile energy deposition. The whisker spectra are dominated by small clusters?the most abundant species being AlO- and AlO2-. Bulk samples have larger yields for AlO2- than for AlO-, while this trend is reversed in whisker samples. Bulk samples give similar abundances of large SI clusters, while whisker samples give an order of magnitude lower yield of these SIs. Effective yields were calculated in order to determine quantitative differences between the nano-objects and bulk samples. The characterization of individual nano-objects from a mixture is demonstrated with negatively charged polymer spheres that are attracted to and retained by the nano-whiskers. The spheres are monodisperse polystyrene nanoparticles (30nm diameter). Our results show that the event-by-event mode can provide information on the nature, size, relative location, and abundance of nano-objects in the field of view. This study presents the first evidence of quantitative molecular information originating from nano-object mixtures. Biologically relevant systems (solid-supported lipid bilayers) were also characterized using Au5 , Au4004 and C60 . Organization-dependent SI emission was observed for phosphocholine bilayers. Lipid domain formation was also investigated in bilayers formed from cholesterol and a mixed lipid system. Trends in the correlation coefficient suggest that cholesterol segregates from the surrounding lipid environment during raft formation.

Pinnick, Veronica Tiffany

2009-12-01T23:59:59.000Z

124

DETERMINATION OF 237NP AND PU ISOTOPES IN LARGE SOIL SAMPLES BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY  

Science Conference Proceedings (OSTI)

A new method for the determination of {sup 237}Np and Pu isotopes in large soil samples has been developed that provides enhanced uranium removal to facilitate assay by inductively coupled plasma mass spectrometry (ICP-MS). This method allows rapid preconcentration and separation of plutonium and neptunium in large soil samples for the measurement of {sup 237}Np and Pu isotopes by ICP-MS. {sup 238}U can interfere with {sup 239}Pu measurement by ICP-MS as {sup 238}UH{sup +} mass overlap and {sup 237}Np via {sup 238}U peak tailing. The method provides enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then transferring Pu to DGA resin for additional purification. The decontamination factor for removal of uranium from plutonium for this method is greater than 1 x 10{sup 6}. Alpha spectrometry can also be applied so that the shorter-lived {sup 238}Pu isotope can be measured successfully. {sup 239}Pu, {sup 242}Pu and {sup 237}Np were measured by ICP-MS, while {sup 236}Pu and {sup 238}Pu were measured by alpha spectrometry.

Maxwell, S.

2010-07-26T23:59:59.000Z

125

Gas-phase and Solution-phase Peptide Conformations Studied by Ion Mobility-mass Spectrometry and Molecular Dynamics Simulations  

E-Print Network (OSTI)

Ion mobility spectrometry (IMS) separates ions on the basis of ion-neutral collision cross-sections (CCS, [omega]), which are determined by the geometry or conformation of the ions. The size-based IM separation can be extended to distinguish conformers that have different shapes in cases where shape differences influence the accessible surface area of the molecule. In recent years, IM has rapidly evolved as a structural characterization technique, which has applied on various structural biology problems. In this work, IMS is combined with molecular dynamics simulation (MDS), specially the integrated tempering sampling molecular dynamics simulation (ITS-MDS) to explore the gas-phase conformation space of two molecular systems (i) protonated tryptophan zipper 1 (trpzip1) ions and its six derivatives (ii) alkali metal ion (Na, K and Cs) adducts of gramicidin A (GA). The structural distributions obtained from ITS-MDS are compared well with results obtained from matrix-assisted laser desorption ionization-ion mobility-mass spectrometry (MALDI-IM-MS) for trpzip 1 series and electrospray ionization-ion mobility-mass spectrometry (ESI-IM-MS) for alkali metal ion adducts of GA. Furthermore, the solvent dependence on conformational preferences of the GA dimer is investigated using a combination of mass spectrometry techniques, viz. ESI-IM-MS and hydrogen/deuterium exchange (HDX)-MS, and MDS. The IM experiments reveal three distinct gramicidin A species, detected as the sodium ion adduct ions, [2GA + 2Na]²?, and the equilibrium abundances of the dimer ions varies with solvent polarity. The solution phase conformations are assigned as the parallel and anti-parallel [beta]-helix dimer, and the anti-parallel dimer is the preferred conformation in non-polar organic solvent. The calculated CCS profiles by ITS-MDS agree very well with the experimentally measured CCS profiles, which underscore the utility of the method for determining candidate structures as well as the relative abundances of the candidate structures. The benefit of combining ion mobility measurements with solution-phase H/D exchange is allowing identifications and detail analysis of the solution-phase subgroup conformations, which cannot be uncovered by one method alone.

Chen, Liuxi

2012-08-01T23:59:59.000Z

126

Formic acid oxidation in a polymer electrolyte fuel cell: A real-time mass-spectrometry study  

Science Conference Proceedings (OSTI)

The electro-oxidation of formic acid was studied in a direct-oxidation polymer-electrolyte fuel cell at 170 C using real-time mass spectrometry. The results are compared with those obtained for methanol oxidation under the same conditions. Formic acid was electrochemically more active than methanol on both Pt-black and Pt-Ru catalysts. The polarization potential of formic acid oxidation was ca. 90 to 100 mV lower than that of methanol. The oxidation of formic acid was dependent on the water/formic acid mole ratio. The best anode performance was obtained using a water/formic acid mole ratio of {approximately}2. In addition, Pt/Ru catalyst was more active than Pt-black for formic acid oxidation. The mass spectrometric results showed that CO{sub 2} is the only reaction product of formic acid oxidation. The results are discussed in terms of possible formic acid oxidation mechanisms.

Weber, M.; Wang, J.T.; Wasmus, S.; Savinell, R.F. [Case Western Reserve Univ., Cleveland, OH (United States)

1996-07-01T23:59:59.000Z

127

Chemical Characterization of Crude Petroleum Using Nanospray Desorption Electrospray Ionization Coupled with High-Resolution Mass Spectrometry  

Science Conference Proceedings (OSTI)

Nanospray desorption electrospray ionization (nano-DESI) combined with high-resolution mass spectrometry was used for the first time for the analysis of liquid petroleum crude oil samples. The analysis was performed in both positive and negative ionization modes using three solvents one of which (acetonitrile/toluene mixture) is commonly used in petroleomics studies while two other polar solvents (acetonitrile/water and methanol/water mixtures) are generally not compatible with petroleum characterization using mass spectrometry. The results demonstrate that nano-DESI analysis efficiently ionizes petroleum constituents soluble in a particular solvent. When acetonitrile/toluene is used as a solvent, nano-DESI generates electrospray-like spectra. In contrast, strikingly different spectra were obtained using acetonitrile/water and methanol/water. Comparison with the literature data indicates that these solvents selectively extract water-soluble constituents of the crude oil. Water-soluble compounds are predominantly observed as sodium adducts in nano-DESI spectra indicating that addition of sodium to the solvent may be a viable approach for efficient ionization of water-soluble crude oil constituents. Nano-DESI enables rapid screening of different classes of compounds in crude oil samples using solvents that are rarely used for petroleum characterization.

Eckert, Peter A.; Roach, Patrick J.; Laskin, Alexander; Laskin, Julia

2012-02-07T23:59:59.000Z

128

Laser desorption/ionization mass spectrometry for direct profiling and imaging of small molecules from raw biological materials  

DOE Green Energy (OSTI)

Matrix-assisted laser desorption/ionization(MALDI) mass spectrometry(MS) has been widely used for analysis of biological molecules, especially macromolecules such as proteins. However, MALDI MS has a problem in small molecule (less than 1 kDa) analysis because of the signal saturation by organic matrixes in the low mass region. In imaging MS (IMS), inhomogeneous surface formation due to the co-crystallization process by organic MALDI matrixes limits the spatial resolution of the mass spectral image. Therefore, to make laser desorption/ionization (LDI) MS more suitable for mass spectral profiling and imaging of small molecules directly from raw biological tissues, LDI MS protocols with various alternative assisting materials were developed and applied to many biological systems of interest. Colloidal graphite was used as a matrix for IMS of small molecules for the first time and methodologies for analyses of small metabolites in rat brain tissues, fruits, and plant tissues were developed. With rat brain tissues, the signal enhancement for cerebroside species by colloidal graphite was observed and images of cerebrosides were successfully generated by IMS. In addition, separation of isobaric lipid ions was performed by imaging tandem MS. Directly from Arabidopsis flowers, flavonoids were successfully profiled and heterogeneous distribution of flavonoids in petals was observed for the first time by graphite-assisted LDI(GALDI) IMS.

Cha, Sangwon

2008-05-15T23:59:59.000Z

129

Deconstruction of Activity-Dependent Covalent Modification of Heme in Human Neutrophil Myeloperoxidase by Multistage Mass Spectrometry (MS[superscript 4])  

SciTech Connect

Myeloperoxidase (MPO) is known to be inactivated and covalently modified by treatment with hydrogen peroxide and agents similar to 3-(2-ethoxypropyl)-2-thioxo-2,3-dihydro-1H-purin-6(9H)-one (1), a 254.08 Da derivative of 2-thioxanthine. Peptide mapping by liquid chromatography and mass spectrometry detected modification by 1 in a labile peptide-heme-peptide fragment of the enzyme, accompanied by a mass increase of 252.08 Da. The loss of two hydrogen atoms was consistent with mechanism-based oxidative coupling. Multistage mass spectrometry (MS{sup 4}) of the modified fragment in an ion trap/Orbitrap spectrometer demonstrated that 1 was coupled directly to heme. Use of a 10 amu window delivered the full isotopic envelope of each precursor ion to collision-induced dissociation, preserving definitive isotopic profiles for iron-containing fragments through successive steps of multistage mass spectrometry. Iron isotope signatures and accurate mass measurements supported the structural assignments. Crystallographic analysis confirmed linkage between the methyl substituent of the heme pyrrole D ring and the sulfur atom of 1. The final orientation of 1 perpendicular to the plane of the heme ring suggested a mechanism consisting of two consecutive one-electron oxidations of 1 by MPO. Multistage mass spectrometry using stage-specific collision energies permits stepwise deconstruction of modifications of heme enzymes containing covalent links between the heme group and the polypeptide chain.

Geoghegan, Kieran F.; Varghese, Alison H.; Feng, Xidong; Bessire, Andrew J.; Conboy, James J.; Ruggeri, Roger B.; Ahn, Kay; Spath, Samantha N.; Filippov, Sergey V.; Conrad, Steven J.; Carpino, Philip A.; Guimarães, Cristiano R.W.; Vajdos, Felix F. (Pfizer)

2013-03-07T23:59:59.000Z

130

New Mass and Lifetime Measurements of $^{152}$Sm Projectile Fragments with Time-Resolved Schottky Mass Spectrometry  

E-Print Network (OSTI)

The FRS-ESR facilities at GSI provide unique conditions for precision measurements with stored exotic nuclei over a large range in the chart of nuclides. In the present experiment the exotic nuclei were produced via fragmentation of $^{152}$Sm projectiles in a thick beryllium target at 500-600 MeV/u, separated in-flight with the fragment separator FRS, and injected into the storage-cooler ring ESR. Mass and lifetime measurements have been performed with bare and few-electron ions. The experiment and first results will be presented in this contribution.

Litvinov, Y A; Geissel, H; Weick, H; Beckert, Karl; Beller, Peter; Boutin, D; Brandau, C; Chen, L; Klepper, O; Knöbel, R; Kozhuharov, C; Kurcewicz, J; Litvinov, S A; Mazzocco, M; Münzenberg, G; Nociforo, C; Nolden, F; Plass, W; Scheidenberger, C; Steck, Markus; Sun, B; Winkler, M; Litvinov, Yu.A.

2005-01-01T23:59:59.000Z

131

Organic aerosol components observed in Northern Hemispheric datasets from Aerosol Mass Spectrometry  

E-Print Network (OSTI)

In this study we compile and present results from the factor analysis of 43 Aerosol Mass Spectrometer (AMS) datasets (27 of the datasets are reanalyzed in this work). The components from all sites, when taken together, ...

Kroll, Jesse

132

Elemental analysis of aerosol organic nitrates with electron ionization high-resolution mass spectrometry  

E-Print Network (OSTI)

Four hydroxynitrates (R(OH)R'ONO2) representative of atmospheric volatile organic compound (VOC) oxidation products were synthesized, nebulized and sampled into an Aerodyne High Resolution Time of Flight Aerosol Mass ...

Rollins, A. W.

133

First accelerator mass spectrometry {sup 14}C dates documenting contemporaneity of nonanalog species in late Pleistocene mammal communities  

Science Conference Proceedings (OSTI)

Worldwide late Pleistocene terrestrial mammal faunas are characterized by stratigraphic associations of species that now have exclusive geographic ranges. These have been interpreted as either taphonomically mixed or representative of communities that no longer exist. Accelerator mass spectrometry {sup 14}C dates (n = 60) on single bones of stratigraphically associated fossil micromammals from two American and two Russian sites document for the first time that currently allopatric mammals occurred together between 12,000 and 22,000 yr B.P. on two continents. The existence of mammal communities without modern analogs demonstrates that Northern Hemisphere biological communities are ephemeral and that many modern biomes are younger than 12 ka. Future climate change may result in new nonanalog communities.

Stafford, T.W. Jr.; Semken, H.A. Jr.; Graham, R.W.; Klippel, W.F.; Markova, A.; Smirnov, N.G.; Southon, J.

1999-10-01T23:59:59.000Z

134

Beam Purification by Photodetachment  

Science Conference Proceedings (OSTI)

Ion beam purity is of crucial importance to many basic and applied studies. Selective photodetachment has been proposed to suppress unwanted species in negative ion beams while preserving the intensity of the species of interest. A highly efficient technique based on photodetachment in a gas-filled radio frequency quadrupole ion cooler has been demonstrated. In off-line experiments with stable ions, up to 104 times suppression of the isobar contaminants in a number of interesting radioactive negative ion beams has been demonstrated. For selected species, this technique promises experimental possibilities in studies on exotic nuclei, accelerator mass spectrometry, and fundamental properties of negative atomic and molecular ions.

Liu, Yuan [ORNL; Beene, James R [ORNL; Havener, Charles C [ORNL; Galindo-Uribarri, Alfredo {nmn} [ORNL; Andersson, P. [University of Gothenburg, Sweden; Lindahl, A. O. [University of Gothenburg, Sweden; Hanstorp, D. [University of Gothenburg, Sweden; Forstner, Dr. Oliver [University of Vienna, Austria; Gottwald, T. [Johannes Gutenberg-Universitaet Mainz, Mainz, Germany; Wendt, K. [Johannes Gutenberg-Universitaet Mainz, Mainz, Germany

2012-01-01T23:59:59.000Z

135

Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry  

DOE Patents (OSTI)

The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent. 8 figs.

Yeung, E.S.; Chang, Y.C.

1999-06-29T23:59:59.000Z

136

High-Resolution Electrospray Ionization Mass Spectrometry Analysis of Water- Soluble Organic Aerosols Collected with a Particle into Liquid Sampler  

DOE Green Energy (OSTI)

This work demonstrates the utility of a particle-into-liquid sampler (PILS) a technique traditionally used for identification of inorganic ions present in ambient or laboratory aerosols for the analysis of water soluble organic aerosol (OA) using high resolution electrospray ionization mass spectrometry (HR ESI-MS). Secondary organic aerosol (SOA) was produced from 0.5 ppm mixing ratios of limonene and ozone in a 5 m3 Teflon chamber. SOA was collected simultaneously using a traditional filter sampler and a PILS. The filter samples were later extracted with either water or acetonitrile, while the aqueous PILS samples were analyzed directly. In terms of peak intensities, types of detectable compounds, average O:C ratios, and organic mass to organic carbon ratios, the resulting high resolution mass spectra were essentially identical for the PILS and filter based samples. SOA compounds extracted from both filter/acetonitrile extraction and PILS/water extraction accounted for >95% of the total ion current in ESI mass spectra. This similarity was attributed to high solubility of limonene SOA in water. In contrast, significant differences in detected ions and peak abundances were observed for pine needle biomass burning organic aerosol (BBOA) collected with PILS and filter sampling. The water soluble fraction of BBOA is considerably smaller than for SOA, and a number of unique peaks were detectable only by the filter/acetonitrile method. The combination of PILS collection with HR-ESI-MS analysis offers a new approach for molecular analysis of the water-soluble organic fraction in biogenic SOA, aged photochemical smog, and BBOA.

Bateman, Adam P.; Nizkorodov, Serguei; Laskin, Julia; Laskin, Alexander

2010-10-01T23:59:59.000Z

137

Mass spectrometry-based methods for detection and differentiation of botulinum neurotoxins  

DOE Patents (OSTI)

The present invention is directed to a method for detecting the presence of clostridial neurotoxins in a sample by mixing a sample with a peptide that can serve as a substrate for proteolytic activity of a clostridial neurotoxin; and measuring for proteolytic activity of a clostridial neurotoxin by a mass spectroscopy technique. In one embodiment, the peptide can have an affinity tag attached at two or more sites.

Schmidt, Jurgen G. (Los Alamos, NM); Boyer, Anne E. (Atlanta, GA); Kalb, Suzanne R. (Atlanta, GA); Moura, Hercules (Tucker, GA); Barr, John R. (Suwannee, GA); Woolfitt, Adrian R. (Atlanta, GA)

2009-11-03T23:59:59.000Z

138

Development of a detection method for {244}Pu by resonance ionization mass spectrometry.  

Science Conference Proceedings (OSTI)

The long-lived actinide {sup 244}Pu (t{sub 1/2} = 81 Myr) is expected to be present in the Interstellar Medium from fresh r-process nucleosynthesis or in direct ejecta from supernovae. Deposition onto Earth may result in traces of live {sup 244}Pu in suitable reservoirs. We are developing a method for {sup 244}Pu detection based on resonance ionization mass spectroscopy. Using Gd as a proxy, we determine an overall efficiency of 0.5% in conditions applicable to the detection of Pu, and present preliminary results on Pu detection.

Ofan, A.; Ahmad, I.; Greene, J. P.; Paul, M.; Savina, M. R. (Materials Science Division); ( PHY); (Hebrew Univ.)

2006-07-01T23:59:59.000Z

139

Enzymatic Digestion in Aqueous-Organic Solvents: A Mass Spectrometry-Based Approach in Monitoring Protein Conformation Changes  

E-Print Network (OSTI)

The three dimensional structure of a protein is important for its function. When misfolded, a protein may be rendered inactive or adapt a conformation that could be toxic. Studying protein folding requires an understanding of protein conformation. Traditionally, protein conformation has been studied using x-ray crystallography and nuclear magnetic resonance (NMR). X-ray crystallography is limited in the analysis of crystallized proteins and is computationally intensive. NMR deals with proteins in solution but reports only an average of conformation and the technique severely suffers from spectral overlapping due to the thousands of resonances of the protein. More recently, mass spectrometry has been employed not only to elucidate primary structures but also gather information on the three-dimensional conformation of proteins. In this study, a mass spectrometric-based approach is used to study the changes in conformation of cytochrome c and the green fluorescent protein when subjected to aqueous-organic solvent systems. The technique involved trypsin digestion and generation of peptide mass maps. For cytochrome c, the experiments were done with ethanol, methanol and acetonitrile to gain insights on naturation and denaturation. An apparent solvent effect to the rate of digestion and propensity for missed cleavages attributed to weakening of hydrophobic interactions and strengthening of intramolecular hydrogen bonding was observed. For the green fluorescent protein, sulfolane, a known supercharging agent, was used to gain insights on the effect of supercharging to protein conformation. Addition of 2.0% sulfolane shifted the charge state envelope of the protein towards lower m/z while adding lower amounts of sulfolane enhanced lower charge states while broadening the charge state envelope. The time course study showed different patterns of digestion dependent on solvent conditions implying changes in conformation. Furthermore, absorbance and fluorescence measurements suggested that addition of sulfolane protects the fluorophore from quenching. The activity of trypsin is not affected by addition of low amounts of sulfolane.

Tuvilla, Mavreen Rose

2013-05-01T23:59:59.000Z

140

Simple and inexpensive time-of-flight charge-to-mass analyzer for ion beam source characterization  

SciTech Connect

We describe the design, electronics, and test results of a simple and low-cost time-of-flight ion charge-to-mass analyzer that is suitable for ion source characterization. The method selects a short-time sample of the beam whose charge-to-mass composition is then separated according to ion velocity and detected by a remote Faraday cup. The analyzer is a detachable device that has been used for rapid analysis of charge-to-mass composition of ion beams accelerated by voltages of up to about 100 kV.

Gushenets, V. I.; Nikolaev, A. G.; Oks, E. M.; Vintizenko, L. G.; Yushkov, G. Yu.; Oztarhan, A.; Brown, I. G. [High Current Electronics Institute, Russian Academy of Sciences, 2/3 Akademichesky Avenue, Tomsk 634055 (Russian Federation); Ege University, Bornova-Izmir 35100 (Turkey); Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States)

2006-06-15T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Electrodeposition of Technetium on Platinum for Thermal Ionization Mass Spectrometry (TIMS)  

Science Conference Proceedings (OSTI)

A novel device has been fabricated for the electrodeposition of technetium metal onto platinum filaments for thermal ionization mass spectrometric (TIMS) measurements. The ability of the device to focus the deposition to diameters of hundreds of micrometers on pre-mounted TIMS filaments coupled with the ease of use and simplicity of design permit for an extremely sensitive yet economical TIMS filament loading technique. Electrodeposition parameters were varied in order to maximize deposition efficiency. X-ray photoelectron spectroscopy (XPS) was used to confirm and characterize the technetium deposit. The technetium is deposited in the metallic state, although surface oxides in the 4+ and 7+ state form readily. Initial TIMS measurements of the electrodeposited technetium in the presence of a barium sulfate ionization enhancer show potential for excellent sensitivity.

Engelmann, Mark D.; Metz, Lori A.; Delmore, James E.; Engelhard, Mark H.; Ballou, Nathan E.

2008-05-15T23:59:59.000Z

142

Single Particle Laser Mass Spectrometry Applied to Differential Ice Nucleation Experiments at the AIDA Chamber  

SciTech Connect

Experiments conducted at the Aerosol Interactions and Dynamics in the Atmosphere (AIDA) chamber located in Karlsruhe, Germany permit investigation of particle properties that affect the nucleation of ice at temperature and water vapor conditions relevant to cloud microphysics and climate issues. Ice clouds were generated by heterogeneous nucleation of Arizona test dust (ATD), illite, and hematite and homogeneous nucleation of sulfuric acid. Ice crystals formed in the chamber were inertially separated from unactivated, or ‘interstitial’ aerosol particles with a pumped counterflow virtual impactor (PCVI), then evaporated. The ice residue (i.e., the aerosol which initiated ice nucleation plus any material which was scavenged from the gas- and/or particle-phase), was chemically characterized at the single particle level using a laser ionization mass spectrometer. In this manner the species that first nucleated ice could be identified out of a mixed aerosol population in the chamber. Bare mineral dust particles were more effective ice nuclei (IN) than similar particles with a coating. Metallic particles from contamination in the chamber initiated ice nucleation before other species but there were few enough that they did not compromise the experiments. Nitrate, sulfate, and organics were often detected on particles and ice residue, evidently from scavenging of trace gas-phase species in the chamber. Hematite was a more effective ice nucleus than illite. Ice residue was frequently larger than unactivated test aerosol due to the formation of aggregates due to scavenging, condensation of contaminant gases, and the predominance of larger aerosol in nucleation.

Gallavardin, S. J.; Froyd, Karl D.; Lohmann, U.; Moehler, Ottmar; Murphy, Daniel M.; Cziczo, Dan

2008-08-26T23:59:59.000Z

143

Determination of total chlorine and bromine in solid wastes by sintering and inductively coupled plasma-sector field mass spectrometry  

Science Conference Proceedings (OSTI)

A sample preparation method based on sintering, followed by analysis by inductively coupled plasma-sector field mass spectrometry (ICP-SFMS) for the simultaneous determination of chloride and bromide in diverse and mixed solid wastes, has been evaluated. Samples and reference materials of known composition were mixed with a sintering agent containing Na{sub 2}CO{sub 3} and ZnO and placed in an oven at 560 deg. C for 1 h. After cooling, the residues were leached with water prior to a cation-exchange assisted clean-up. Alternatively, a simple microwave-assisted digestion using only nitric acid was applied for comparison. Thereafter the samples were prepared for quantitative analysis by ICP-SFMS. The sintering method was evaluated by analysis of certified reference materials (CRMs) and by comparison with US EPA Method 5050 and ion chromatography with good agreement. Median RSDs for the sintering method were determined to 10% for both chlorine and bromine, and median recovery to 96% and 97%, respectively. Limits of detection (LODs) were 200 mg/kg for chlorine and 20 mg/kg for bromine. It was concluded that the sintering method is suitable for chlorine and bromine determination in several matrices like sewage sludge, plastics, and edible waste, as well as for waste mixtures. The sintering method was also applied for determination of other elements present in anionic forms, such as sulfur, arsenic, selenium and iodine.

Osterlund, Helene [Division of Applied Geology, Lulea University of Technology, S-971 87 Lulea (Sweden); ALS Scandinavia AB, ALS Laboratory Group, Aurorum 10, S-977 75 Lulea (Sweden)], E-mail: Helene.Osterlund@alsglobal.com; Rodushkin, Ilia [Division of Applied Geology, Lulea University of Technology, S-971 87 Lulea (Sweden); ALS Scandinavia AB, ALS Laboratory Group, Aurorum 10, S-977 75 Lulea (Sweden); Ylinenjaervi, Karin; Baxter, Douglas C. [ALS Scandinavia AB, ALS Laboratory Group, Aurorum 10, S-977 75 Lulea (Sweden)

2009-04-15T23:59:59.000Z

144

Oxidative degradation of bis (2,4,4-trimethylpentyl) dithiophosphinic acid in nitric acid studied by electrospray ionization mass spectrometry  

SciTech Connect

Samples of bis(2,4,4-trimethylpentyl)dithiophosphinic acid (Cyanex-301) were analyzed using direct infusion electrospray ionization mass spectrometry. Positive ion spectra of standard and stereo-pure acids displayed ions typical of the unmodified compound, cationized monomeric and dimeric cluster ion species. In addition, a significant ions 2 u less than the dimeric clusters were seen, that correspond to an oxidatively coupled species designated Cyx2 that is observed as H- or Na-cationized species in the electrospray analyses. Based on uncorrected ion intensities, Cyx2 is estimated to account for about 20% of the total in the standard materials. When samples that were contacted with 3 M HNO3 were analyzed, the positive ion spectrum consisted nearly entirely of ions derived from the oxidatively coupled product, indicating that the acid promotes coupling. The negative ion spectra of the standard acids consisted nearly entirely of the conjugate base that is formed by deprotonation of the acids, and cluster ions containing multiple acid molecules. The negative spectra of the HNO3-contacted samples also contained the conjugate base of the unmodified acid, but also two other species that correspond to the dioxo- and perthio- derivatives. It is concluded that HNO3 contact causes significant oxidation, forming at least three major products, Cyx2, the perthio-acid, and the dioxo-acid.

G. S. Groenewold; D. R. Peterman

2012-10-01T23:59:59.000Z

145

Quantifying Uranium Isotope Ratios Using Resonance Ionization Mass Spectrometry: The Influence of Laser Parameters on Relative Ionization Probability  

Science Conference Proceedings (OSTI)

Resonance Ionization Mass Spectrometry (RIMS) has been developed as a method to measure relative uranium isotope abundances. In this approach, RIMS is used as an element-selective ionization process to provide a distinction between uranium atoms and potential isobars without the aid of chemical purification and separation. We explore the laser parameters critical to the ionization process and their effects on the measured isotope ratio. Specifically, the use of broad bandwidth lasers with automated feedback control of wavelength was applied to the measurement of {sup 235}U/{sup 238}U ratios to decrease laser-induced isotopic fractionation. By broadening the bandwidth of the first laser in a 3-color, 3-photon ionization process from a bandwidth of 1.8 GHz to about 10 GHz, the variation in sequential relative isotope abundance measurements decreased from >10% to less than 0.5%. This procedure was demonstrated for the direct interrogation of uranium oxide targets with essentially no sample preparation. A rate equation model for predicting the relative ionization probability has been developed to study the effect of variation in laser parameters on the measured isotope ratio. This work demonstrates that RIMS can be used for the robust measurement of uranium isotope ratios.

Isselhardt, B H

2011-09-06T23:59:59.000Z

146

B American Society for Mass Spectrometry, 2011 DOI: 10.1007/s13361-011-0217-6  

E-Print Network (OSTI)

Abstract A new, two-dimensional overtone mobility spectrometry (OMS-OMS) instrument is described Spectrom. (2011) 22:2049Y2060 RESEARCH ARTICLE Overtone Mobility Spectrometry: Part 4. OMS-OMS Analyses for the analysis of complex peptide mixtures. OMS separations are based on the differences in mobilities of ions

Clemmer, David E.

147

B American Society for Mass Spectrometry, 2011 DOI: 10.1007/s13361-011-0087-y  

E-Print Network (OSTI)

Spectrom. (2011) 22:804Y816 RESEARCH ARTICLE Overtone Mobility Spectrometry: Part 3. On the Origin of Peaks The origin of non-integer overtone peaks in overtone mobility spectrometry (OMS) spectra is investigated of peaks. The new equation makes it possible to determine collision cross sections from any OMS peak

Clemmer, David E.

148

Interlaboratory Validation of EPA 1600 Series Methods: Draft EPA Method 1638 for Analysis of Metals in Water by Inductively Coupled Plasma -- Mass Spectrometry (ICP-MS)  

Science Conference Proceedings (OSTI)

Federal and state permits are requiring wastewater dischargers to monitor for ever lower concentrations of trace metals, in some cases at levels that may preclude reliable measurement. In this joint EPA-EPRI interlaboratory data collection effort, eight laboratories evaluated draft EPA Method 1638: Determination of Trace Elements in Ambient Water by Inductively Coupled Plasma-Mass Spectrometry. This method is intended for the analysis of low levels (parts per trillion) of antimony, cadmium, copper, lead,...

2000-11-27T23:59:59.000Z

149

SAMPLING AND MASS SPECTROMETRY APPROACHES FOR THE DETECTION OF DRUGS AND FOREIGN CONTAMINANTS IN BREATH FOR HOMELAND SECURITY APPLICATIONS  

Science Conference Proceedings (OSTI)

Homeland security relies heavily on analytical chemistry to identify suspicious materials and persons. Traditionally this role has focused on attribution, determining the type and origin of an explosive, for example. But as technology advances, analytical chemistry can and will play an important role in the prevention and preemption of terrorist attacks. More sensitive and selective detection techniques can allow suspicious materials and persons to be identified even before a final destructive product is made. The work presented herein focuses on the use of commercial and novel detection techniques for application to the prevention of terrorist activities. Although drugs are not commonly thought of when discussing terrorism, narcoterrorism has become a significant threat in the 21st century. The role of the drug trade in the funding of terrorist groups is prevalent; thus, reducing the trafficking of illegal drugs can play a role in the prevention of terrorism by cutting off much needed funding. To do so, sensitive, specific, and robust analytical equipment is needed to quickly identify a suspected drug sample no matter what matrix it is in. Single Particle Aerosol Mass Spectrometry (SPAMS) is a novel technique that has previously been applied to biological and chemical detection. The current work applies SPAMS to drug analysis, identifying the active ingredients in single component, multi-component, and multi-tablet drug samples in a relatively non-destructive manner. In order to do so, a sampling apparatus was created to allow particle generation from drug tablets with on-line introduction to the SPAMS instrument. Rules trees were developed to automate the identification of drug samples on a single particle basis. A novel analytical scheme was also developed to identify suspect individuals based on chemical signatures in human breath. Human breath was sampled using an RTube{trademark} and the trace volatile organic compounds (VOCs) were preconcentrated using solid phase microextraction (SPME) and identified using gas chromatography - mass spectrometry (GC-MS). Modifications to the sampling apparatus allowed for increased VOC collection efficiency, and reduced the time of sampling and analysis by over 25%. The VOCs are present in breath due to either endogenous production, or exposure to an external source through absorption, inhalation, or ingestion. Detection of these exogenous chemicals can provide information on the prior location and activities of the subject. Breath samples collected before and after exposure in a hardware store and nail salon were analyzed to investigate the prior location of a subject; breath samples collected before and after oral exposure to terpenes and terpenoid compounds, pseudoephedrine, and inhalation exposure to hexamine and other explosive related compounds were analyzed to investigate the prior activity of a subject. The elimination of such compounds from the body was also monitored. In application, this technique may provide an early warning system to identify persons of interest in the prevention and preemption stages of homeland security.

Martin, A N

2009-01-27T23:59:59.000Z

150

Radiation environment simulations at the Tevatron, studies of the beam profile and measurement of the Bc meson mass  

Science Conference Proceedings (OSTI)

The description of a computer simulation of the CDF detector at Fermilab and the adjacent accelerator parts is detailed, with MARS calculations of the radiation background in various elements of the model due to the collision of beams and machine-related losses. Three components of beam halo formation are simulated for the determination of the principal source of radiation background in CDF due to beam losses. The effect of a collimator as a protection for the detector is studied. The simulation results are compared with data taken by a CDF group. Studies of a 150 GeV Tevatron proton beam are performed to investigate the transverse diffusion growth and distribution. A technique of collimator scan is used to scrape the beam under various experimental conditions, and computer programs are written for the beam reconstruction. An average beam halo growth speed is given and the potential of beam tail reconstruction using the collimator scan is evaluated. A particle physics analysis is conducted in order to detect the B{sub c} {yields} J/{psi}{pi} decay signal with the CDF Run II detector in 360 pb{sup -1} of data. The cut variables and an optimization method to determine their values are presented along with a criterion for the detection threshold of the signal. The mass of the B{sub c} meson is measured with an evaluation of the significance of the signal.

Nicolas, Ludovic Y.; /Glasgow U.

2005-09-01T23:59:59.000Z

151

Competitive fragmentation pathways of acetic acid dimer explored by synchrotron VUV photoionization mass spectrometry and electronic structure calculations  

Science Conference Proceedings (OSTI)

In present study, photoionization and dissociation of acetic acid dimers have been studied with the synchrotron vacuum ultraviolet photoionization mass spectrometry and theoretical calculations. Besides the intense signal corresponding to protonated cluster ions (CH{sub 3}COOH){sub n}{center_dot}H{sup +}, the feature related to the fragment ions (CH{sub 3}COOH)H{sup +}{center_dot}COO (105 amu) via {beta}-carbon-carbon bond cleavage is observed. By scanning photoionization efficiency spectra, appearance energies of the fragments (CH{sub 3}COOH){center_dot}H{sup +} and (CH{sub 3}COOH)H{sup +}{center_dot}COO are obtained. With the aid of theoretical calculations, seven fragmentation channels of acetic acid dimer cations were discussed, where five cation isomers of acetic acid dimer are involved. While four of them are found to generate the protonated species, only one of them can dissociate into a C-C bond cleavage product (CH{sub 3}COOH)H{sup +}{center_dot}COO. After surmounting the methyl hydrogen-transfer barrier 10.84 {+-} 0.05 eV, the opening of dissociative channel to produce ions (CH{sub 3}COOH){sup +} becomes the most competitive path. When photon energy increases to 12.4 eV, we also found dimer cations can be fragmented and generate new cations (CH{sub 3}COOH){center_dot}CH{sub 3}CO{sup +}. Kinetics, thermodynamics, and entropy factors for these competitive dissociation pathways are discussed. The present report provides a clear picture of the photoionization and dissociation processes of the acetic acid dimer in the range of the photon energy 9-15 eV.

Guan Jiwen; Hu Yongjun; Zou Hao [MOE Key laboratory of Laser Life Science and Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631 (China); Cao Lanlan; Liu Fuyi; Shan Xiaobin; Sheng Liusi [National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui 230029 (China)

2012-09-28T23:59:59.000Z

152

Characterization of human expired breath by solid phase microextraction and analysis using gas chromatography-mass spectrometry and differential mobility spectrometry  

E-Print Network (OSTI)

Breath analysis has potential to become a new medical diagnostic modality. In this thesis, a method for the analysis of human expired breath was developed using gas chromatography-mass spectroscopy. It was subsequently ...

Merrick, William (William F. W.)

2005-01-01T23:59:59.000Z

153

New approaches for the chemical and physical characterization of aerosols using a single particle mass spectrometry based technique  

E-Print Network (OSTI)

1-2% of the oil mass, however the calcium ion peak at m/z 40and elemental carbon (EC) peaks. The HDDV oil mass spectraoil mass spectra were characterized by an intense Ca + ion peak and

Spencer, Matthew Todd

2007-01-01T23:59:59.000Z

154

International Journal of Mass Spectrometry 309 (2012) 154160 Contents lists available at SciVerse ScienceDirect  

E-Print Network (OSTI)

.elsevier.com/locate/ijms Extracted fragment ion mobility distributions: A new method for complex mixture analysis Sunyoung Lee, Zhiyu isomers a b s t r a c t A new method is presented for constructing ion mobility distributions of precursor 2011 Available online 22 September 2011 Keywords: Ion mobility spectrometry Collision

Clemmer, David E.

155

New approaches for the chemical and physical characterization of aerosols using a single particle mass spectrometry based technique  

E-Print Network (OSTI)

mass fractions in particles. Aerosol Science and Technology,mediated lung injury, J. Aerosol Sci. , 29 (5-6), 553-560,from natural to anthropogenic aerosol radiative forcing:

Spencer, Matthew Todd

2007-01-01T23:59:59.000Z

156

Laser ablation-inductively coupled plasma-mass spectrometry: Examinations of the origins of polyatomic ions and advances in the sampling of particulates  

SciTech Connect

This dissertation provides a general introduction to Inductively coupled plasma-mass spectrometry (ICP-MS) and laser ablation (LA) sampling, with an examination of analytical challenges in the employment of this technique. It discusses the origin of metal oxide ions (MO+) in LA-ICP-MS, as well as the effect of introducing helium and nitrogen to the aerosol gas flow on the formation of these polyatomic interferences. It extends the study of polyatomic ions in LA-ICP-MS to metal argide (MAr+) species, an additional source of possible significant interferences in the spectrum. It describes the application of fs-LA-ICP-MS to the determination of uranium isotope ratios in particulate samples.

Witte, Travis

2011-11-30T23:59:59.000Z

157

Determination of the {sup 22}Ne{sub nucl}/{sup 4}He{sub rad} ratio in natural uranium-rich fluorite by mass spectrometry  

Science Conference Proceedings (OSTI)

A determination by noble gas mass spectrometry of {sup 22}Ne production through the combined reactions {sup 19}F({alpha},n){sup 22}Na({beta}{sup +}){sup 22}Ne and {sup 19}F({alpha},p){sup 22}Ne on natural calcium fluoride is made for the first time. Six samples of U-rich fluorite from a fluorspar deposit in Mexico were used to determine the {sup 22}Ne{sub nucl}/{sup 4}He{sub rad} ratio generated by the spontaneous decay of U during the last 32 Ma. The obtained ratio (1.33 {+-} 0.11) x10{sup -5} (95% confidence), is compared to other experimental data on natural uranium oxides and theoretical values.

Sole, Jesus; Pi, Teresa [Instituto de Geologia, Universidad Nacional Autonoma de Mexico, Cd. Universitaria, Coyoacan, 04510 Mexico D.F. (Mexico)

2006-10-15T23:59:59.000Z

158

MANTRA: An Integral Reactor Physics Experiment to Infer Actinide Capture Cross-sections from Thorium to Californium with Accelerator Mass Spectrometry  

SciTech Connect

The principle of the proposed experiment is to irradiate very pure actinide samples in the Advanced Test Reactor at INL and, after a given time, determine the amount of the different transmutation products. The determination of the nuclide densities before and after neutron irradiation will allow inference of effective neutron capture cross-sections. This approach has been used in the past and the novelty of this experiment is that the atom densities of the different transmutation products will be determined using the Accelerator Mass Spectrometry technique at the ATLAS facility located at ANL. It is currently planned to irradiate the following isotopes: 232Th, 235U, 236U, 238U, 237Np, 238Pu, 239Pu, 240Pu, 241Pu, 242Pu, 241Am, 243Am, 244Cm and 248Cm.

G. Youinou; C. McGrath; G. Imel; M. Paul; R. Pardo; F. Kondev; M. Salvatores; G. Palmiotti

2011-08-01T23:59:59.000Z

159

Multiplexed Ion Mobility Spectrometry-Orthogonal Time-of ...  

Multiplexed Ion Mobility Spectrometry-Orthogonal Time-of-Flight Mass Spectrometry Mikhail E. Belov, ... in the multiplexed IMS-TOF MS experiments ...

160

Development of A Cryogenic Drift Cell Spectrometer and Methods for Improving the Analytical Figures of Merit for Ion Mobility-Mass Spectrometry Analysis  

E-Print Network (OSTI)

A cryogenic (325-80 K) ion mobility-mass spectrometer was designed and constructed in order to improve the analytical figures-of-merit for the chemical analysis of small mass analytes using ion mobility-mass spectrometry. The instrument incorporates an electron ionization source, a quadrupole mass spectrometer, a uniform field drift cell spectrometer encased in a cryogenic envelope, and an orthogonal geometry time-of-flight mass spectrometer. The analytical benefits of low temperature ion mobility are discussed in terms of enhanced separation ability, ion selectivity and sensitivity. The distinction between resolving power and resolution for ion mobility is also discussed. Detailed experimental designs and rationales are provided for each instrument component. Tuning and calibration data and methods are also provided for the technique. Proof-of-concept experiments for an array of analytes including rare gases (argon, krypton, xenon), hydrocarbons (acetone, ethylene glycol, methanol), and halides (carbon tetrachloride) are provided in order to demonstrate the advantages and limitations of the instrument for obtaining analytically useful information. Trendline partitioning of small analyte ions based on chemical composition is demonstrated as a novel chemical analysis method. The utility of mobility-mass analysis for mass selected ions is also demonstrated, particularly for probing the ion chemistry which occurs in the drift tube for small mass ions. As a final demonstration of the separation abilities of the instrument, the electronic states of chromium and titanium (ground and excited) are separated with low temperature. The transition metal electronic state separations demonstrated here are at the highest resolution ever obtained for ion mobility methods. The electronic conformational mass isomers of methanol (conventional and distonic) are also partially separated at low temperature. Various drift gases (helium, neon, and argon) are explored for the methanol system in order to probe stronger ion-neutral interaction potentials and effectuate higher resolution separations of the two isomeric ions. Finally, two versatile ion source designs and a method for axially focusing ions at low pressure (1-10 torr) using electrostatic fields is presented along with some preliminary work on the ion sources.

May, Jody C.

2009-08-01T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

B American Society for Mass Spectrometry, 2011 DOI: 10.1007/s13361-011-0168-y  

E-Print Network (OSTI)

with collision-induced dissociation MS/MS. Anal. Sci. 25, 985­ 988 (2009) 15. Williams, J.P., Grabenauer, MHz). Periodically, ion packets are released in short (150 s-wide) pulses into a ~3 m long stacked ring) m/z measurement. Roughly 102 ­103 mass spectra are collected per IMS experiment, allowing drift time

Clemmer, David E.

162

Final Technical Report for DE-FG02-06ER15835: Chemical Imaging with 100nm Spatial Resolution: Combining High Resolution Flurosecence Microscopy and Ion Mobility Mass Spectrometry  

SciTech Connect

We have combined, in a single instrument, high spatial resolution optical microscopy with the chemical specificity and conformational selectivity of ion mobility mass spectrometry. We discuss the design and construction of this apparatus as well as our efforts in applying this technique to thin films of molecular semiconductor materials.

Buratto, Steven K. [UC Santa Barbara

2013-09-03T23:59:59.000Z

163

Applications of High-Resolution Electrospray Ionization Mass Spectrometry to Measurements of Average Oxygen to Carbon Ratios in Secondary Organic Aerosols  

Science Conference Proceedings (OSTI)

The applicability of high resolution electrospray ionization mass spectrometry (HR ESI-MS) to measurements of the average oxygen to carbon ratio (O/C) in organic aerosols was investigated. Solutions with known average O/C containing up to 10 standard compounds representative of secondary organic aerosol (SOA) were analyzed and corresponding electrospray ionization efficiencies were quantified. The assumption of equal ionization efficiency commonly used in estimating O/C ratios of organic aerosols was found to be reasonably accurate. We found that the accuracy of the measured O/C ratios increases by averaging the values obtained from both (+) and (-) modes. A correlation was found between the ratio of the ionization efficiencies in the positive and negative ESI modes with the octanol-water partition constant, and more importantly, with the compound's O/C. To demonstrate the utility of this correlation for estimating average O/C values of unknown mixtures, we analyzed the ESI (+) and ESI (-) data for SOA produced by oxidation of limonene and isoprene and compared to online O/C measurements using an aerosol mass spectrometer (AMS). This work demonstrates that the accuracy of the HR ESI-MS methods is comparable to that of the AMS, with the added benefit of molecular identification of the aerosol constituents.

Bateman, Adam P.; Laskin, Julia; Laskin, Alexander; Nizkorodov, Sergey

2012-07-02T23:59:59.000Z

164

Use of Proton-Transfer-Reaction Mass Spectrometry to Characterize Volatile Organic Compound Sources at the La Porte Super Site During the Texas Air Quality Study 2000  

SciTech Connect

Proton-transfer-reaction mass spectrometry (PTR-MS) was deployed for continuous real-time monitoring of volatile organic compounds (VOCs) at a site near the Houston Ship Channel during the Texas Air Quality Study 2000. Overall, 28 ions dominated the PTR-MS mass spectra and were assigned as anthropogenic aromatics (e.g., benzene, toluene, xylenes) and hydrocarbons (propene, isoprene), oxygenated compounds (e.g., formaldehyde, acetaldehyde, acetone, methanol, C7 carbonyls), and three nitrogencontaining compounds (e.g., HCN, acetonitrile and acrylonitrile). Biogenic VOCs were minor components at this site. Propene was the most abundant lightweight hydrocarbon detected by this technique with concentrations up to 100+ nmol mol-1, and was highly correlated with its oxidation products, formaldehyde (up to ~40 nmol mol-1) and acetaldehyde (up to ~80 nmol/mol), with typical ratios close to 1 in propene-dominated plumes. In the case of aromatic species the high time resolution of the obtained data set helped in identifying different anthropogenic sources (e.g., industrial from urban emissions) and testing current emission inventories. A comparison with results from complimentary techniques (gas chromatography, differential optical absorption spectroscopy) was used to assess the selectivity of this on-line technique in a complex urban and industrial VOC matrix and give an interpretation of mass scans obtained by ‘‘soft’’ chemical ionization using proton-transfer via H3O+. The method was especially valuable in monitoring rapidly changing VOC plumes which passed over the site, and when coupled with meteorological data it was possible to identify likely sources.

Karl, Thomas G.; Jobson, B Tom T.; Kuster, W. C.; Williams, Eric; Stutz, Jochen P.; Shetter, Rick; Hall, Samual R.; Goldan, P. D.; Fehsenfeld, Fred C.; Lindinger, Werner

2003-08-19T23:59:59.000Z

165

Beam purification by photodetachment (invited)  

Science Conference Proceedings (OSTI)

Ion beam purity is of crucial importance to many basic and applied studies in nuclear science. Selective photodetachment has been proposed to suppress unwanted species in negative ion beams while preserving the intensity of the species of interest. A highly efficient technique based on photodetachment in a gas-filled radio frequency quadrupole ion cooler has been demonstrated. In off-line experiments with stable ions, up to 10{sup 4} times suppression of the isobar contaminants in a number of interesting radioactive negative ion beams has been demonstrated. For selected species, this technique promises new experimental possibilities in studies on exotic nuclei, accelerator mass spectrometry, and fundamental properties of negative atomic and molecular ions.

Liu, Y.; Beene, J. R.; Galindo-Uribarri, A.; Havener, C. C. [Physics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States); Andersson, P.; Forstner, O. [Vera Laboratory, Fakultaet fuer Physik, Universitaet Wien, AT-1090 Wien (Austria); Gottwald, T.; Wendt, K. [Institute of Physics, Johannes Gutenberg-University Mainz, D-55099 Mainz (Germany); Hanstorp, D.; Lindahl, A. O. [Department of Physics, University of Gothenburg, SE-412 96 Gothenburg (Sweden)

2012-02-15T23:59:59.000Z

166

Feasibility of the detection of trace elements in particulate matter using online High-Resolution Aerosol Mass Spectrometry  

SciTech Connect

The feasibility of using an online thermal-desorption electron-ionization high-resolution aerosol mass spectrometer (AMS) for the detection of particulate trace elements was investigated analyzing data from Mexico City obtained during the MILAGRO 2006 field campaign, where relatively high concentrations of trace elements have been reported. This potential application is of interest due to the real-time data provided by the AMS, its high sensitivity and time resolution, and the widespread availability and use of this instrument. High resolution mass spectral analysis, isotopic ratios, and ratios of different ions containing the same elements are used to constrain the chemical identity of the measured ions. The detection of Cu, Zn, As, Se, Sn, and Sb is reported. There was no convincing evidence for the detection of other trace elements commonly reported in PM. The elements detected tend to be those with lower melting and boiling points, as expected given the use of a vaporizer at 600oC in this instrument. Operation of the AMS vaporizer at higher temperatures is likely to improve trace element detection. The detection limit is estimated at approximately 0.3 ng m-3 for 5-min of data averaging. Concentration time series obtained from the AMS data were compared to concentration records determined from offline analysis of particle samples from the same times and locations by ICP (PM2.5) and PIXE (PM1.1 and PM0.3). The degree of correlation and agreement between the three instruments (AMS, ICP, and PIXE) varied depending on the element. The AMS shows promise for real-time detection of some trace elements, although additional work including laboratory calibrations with different chemical forms of these elements are needed to further develop this technique and to understand the differences with the ambient data from the other techniques. The trace elements peaked in the morning as expected for primary sources, and the many detected plumes suggest the presence of multiple point sources, probably industrial, in Mexico City which are variable in time and space, in agreement with previous studies.

Salcedo, D.; Laskin, Alexander; Shutthanandan, V.; Jimenez, Jose L.

2012-08-10T23:59:59.000Z

167

Isotope ratio analysis of actinides, fission products, and geolocators by high-efficiency multi-collector thermal ionization mass spectrometry  

SciTech Connect

A ThermoFisher 'Triton' multi-collector thermal ionization mass spectrometer (MC-TIMS) was evaluated for trace and ultra-trace level isotoperatioanalysis of actinides (uranium, plutonium, and americium), fission products and geolocators (strontium, cesium, and neodymium). Total efficiencies (atoms loaded to ions detected) of up to 0.5-2% for U, Pu, and Am, and 1-30% for Sr, Cs, and Nd can be reported employing resin bead load techniques onto flat ribbon Re filaments or resin beads loaded into a millimeter-sized cavity drilled into a Re rod. This results in detection limits of <0.1 fg (10{sup 4} atoms to 10{sup 5} atoms) for {sup 239-242+244}Pu, {sup 233+236}U, {sup 241-243}Am, {sup 89,90}Sr, and {sup 134,135,137}Cs, and {le} 1 pg for natural Nd isotopes (limited by the chemical processing blank) using a secondary electron multiplier (SEM) or multiple-ion counters (MICs). Relative standard deviations (RSD) as small as 0.1% and abundance sensitivities of 1 x 10{sup 6} or better using a SEM are reported here. Precisions of RSD {approx} 0.01-0.001% using a multi-collector Faraday cup array can be achieved at sub-nanogram concentrations for strontium and neodymium and are suitable to gain crucial geolocation information. The analytical protocols reported herein are of particular value for nuclear forensic and nuclear safeguard applications.

Bürger, Stefan [New Brunswick Laboratory, Argonne, IL; Riciputi, Lee R [Los Alamos National Laboratory (LANL); Bostick, Debra A [ORNL; Turgeon, Steven [University of Alberta, Edmondton, Canada; McBay, Eddie H [ORNL; Lavelle, Mark [ORNL

2009-01-01T23:59:59.000Z

168

Identification of volatile butyl rubber thermal-oxidative degradation products by cryofocusing gas chromatography/mass spectrometry (cryo-GC/MS).  

Science Conference Proceedings (OSTI)

Chemical structure and physical properties of materials, such as polymers, can be altered as aging progresses, which may result in a material that is ineffective for its envisioned intent. Butyl rubber formulations, starting material, and additives were aged under thermal-oxidative conditions for up to 413 total days at up to 124 %C2%B0C. Samples included: two formulations developed at Kansas City Plant (KCP) (%236 and %2310), one commercially available formulation (%2321), Laxness bromobutyl 2030 starting material, and two additives (polyethylene AC-617 and Vanax MBM). The low-molecular weight volatile thermal-oxidative degradation products that collected in the headspace over the samples were preconcentrated, separated, and detected using cryofocusing gas chromatography mass spectrometry (cryo-GC/MS). The majority of identified degradation species were alkanes, alkenes, alcohols, ketones, and aldehydes. Observations for Butyl %2310 aged in an oxygen-18 enriched atmosphere (18O2) were used to verify when the source of oxygen in the applicable degradation products was from the gaseous environment rather than the polymeric mixture. For comparison purposes, Butyl %2310 was also aged under non-oxidative thermal conditions using an argon atmosphere.

Smith, Jonell Nicole; White, Michael Irvin; Bernstein, Robert; Hochrein, James Michael

2013-02-01T23:59:59.000Z

169

Analysis of Non-Enzymatically Glycated Peptides: Neutral-Loss Triggered MS3 Versus Multi-Stage Activation Tandem Mass Spectrometry  

Science Conference Proceedings (OSTI)

Non-enzymatic glycation of tissue proteins has important implications in the development of complications of diabetes mellitus. While electron transfer dissociation (ETD) has been shown to outperform collision-induced dissociation (CID) in sequencing glycated peptides by tandem mass spectrometry, ETD instrumentation is not yet available in all laboratories. In this study, we evaluated different advanced CID techniques (i.e., neutral-loss triggered MS3 and multi-stage activation) during LC-MSn analyses of Amadori-modified peptides enriched from human serum glycated in vitro. During neutral-loss triggered MS3 experiments, MS3 scans triggered by neutral-losses of 3 H2O or 3 H2O + HCHO produced similar results in terms of glycated peptide identifications. However, neutral losses of 3 H2O resulted in significantly more glycated peptide identifications during multi-stage activation experiments. Overall, the multi-stage activation approach produced more glycated peptide identifications, while the neutral-loss triggered MS3 approach resulted in much higher specificity. Both techniques offer a viable alternative to ETD for identifying glycated peptides when that method is unavailable.

Zhang, Qibin; Petyuk, Vladislav A.; Schepmoes, Athena A.; Orton, Daniel J.; Monroe, Matthew E.; Yang, Feng; Smith, Richard D.; Metz, Thomas O.

2008-10-15T23:59:59.000Z

170

Design and performance of a combined secondary ion mass spectrometry-scanning probe microscopy instrument for high sensitivity and high-resolution elemental three-dimensional analysis  

Science Conference Proceedings (OSTI)

State-of-the-art secondary ion mass spectrometry (SIMS) instruments allow producing 3D chemical mappings with excellent sensitivity and spatial resolution. Several important artifacts however arise from the fact that SIMS 3D mapping does not take into account the surface topography of the sample. In order to correct these artifacts, we have integrated a specially developed scanning probe microscopy (SPM) system into a commercial Cameca NanoSIMS 50 instrument. This new SPM module, which was designed as a DN200CF flange-mounted bolt-on accessory, includes a new high-precision sample stage, a scanner with a range of 100 {mu}m in x and y direction, and a dedicated SPM head which can be operated in the atomic force microscopy (AFM) and Kelvin probe force microscopy modes. Topographical information gained from AFM measurements taken before, during, and after SIMS analysis as well as the SIMS data are automatically compiled into an accurate 3D reconstruction using the software program 'SARINA,' which was developed for this first combined SIMS-SPM instrument. The achievable lateral resolutions are 6 nm in the SPM mode and 45 nm in the SIMS mode. Elemental 3D images obtained with our integrated SIMS-SPM instrument on Al/Cu and polystyrene/poly(methyl methacrylate) samples demonstrate the advantages of the combined SIMS-SPM approach.

Wirtz, Tom; Fleming, Yves; Gerard, Mathieu [Department 'Science and Analysis of Materials' (SAM), Centre de Recherche Public, Gabriel Lippmann, 41 rue du Brill, L-4422 Belvaux (Luxembourg); Gysin, Urs; Glatzel, Thilo; Meyer, Ernst [Department of Physics, Universitaet Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Wegmann, Urs [Department of Physics, Universitaet Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Ferrovac GmbH, Thurgauerstr. 72, CH-8050 Zuerich (Switzerland); Maier, Urs [Ferrovac GmbH, Thurgauerstr. 72, CH-8050 Zuerich (Switzerland); Odriozola, Aitziber Herrero; Uehli, Daniel [SPECS Zurich GmbH, Technoparkstr. 1, CH-8005 Zuerich (Switzerland)

2012-06-15T23:59:59.000Z

171

Detection and Identification of Heme c-Modified Peptides by Histidine Affinity Chromatography, High-Performance Liquid Chromatography-Mass Spectrometry, and Database Searching  

Science Conference Proceedings (OSTI)

Multiheme c-type cytochromes (proteins with covalently attached heme c moieties) play important roles in extracellular metal respiration in dissimilatory metal-reducing bacteria. Liquid chromatography-tandem mass spectrometry-(LC-MS/MS) characterization of c-type cytochromes is hindered by the presence of multiple heme groups, since the heme c modified peptides are typically not observed, or if observed, not identified. Using a recently reported histidine affinity chromatography (HAC) procedure, we enriched heme c tryptic peptides from purified bovine heart cytochrome c, a bacterial decaheme cytochrome, and subjected these samples to LC-MS/MS analysis. Enriched bovine cytochrome c samples yielded three- to six-fold more confident peptide-spectrum matches to heme-c containing peptides than unenriched digests. In unenriched digests of the decaheme cytochrome MtoA from Sideroxydans lithotrophicus ES-1, heme c peptides for four of the ten expected sites were observed by LC-MS/MS; following HAC fractionation, peptides covering nine out of ten sites were obtained. Heme c peptide spiked into E. coli lysates at mass ratios as low as 10-4 was detected with good signal-to-noise after HAC and LC-MS/MS analysis. In addition to HAC, we have developed a proteomics database search strategy that takes into account the unique physicochemical properties of heme c peptides. The results suggest that accounting for the double thioether link between heme c and peptide, and the use of the labile heme fragment as a reporter ion, can improve database searching results. The combination of affinity chromatography and heme-specific informatics yielded increases in the number of peptide-spectrum matches of 20-100-fold for bovine cytochrome c.

Merkley, Eric D.; Anderson, Brian J.; Park, Jea H.; Belchik, Sara M.; Shi, Liang; Monroe, Matthew E.; Smith, Richard D.; Lipton, Mary S.

2012-12-07T23:59:59.000Z

172

High-efficiency cross-beam magnetic electron-impact source for improved miniature Mattauch-Herzog mass spectrometer performance  

Science Conference Proceedings (OSTI)

We describe a newly designed cross-beam magnetic electron-impact ion source (CBM-EI). We demonstrate its superiority in comparison with a conventional source (CB-EI) when used with a commercial miniature sector-field-type, non-scanning mass spectrometer featuring Mattauch-Herzog geometry (MH-MS) and a permanent sector-field magnet. This paper clearly shows the value of the CBM-EI for enhancing MH-MS sensitivity. Unlike secondary electron-multiplier type detectors, the pixelated detector (IonCCD Trade-Mark-Sign ) used in the commercial MH-MS has no gain. The MH-MS/IonCCD system is therefore challenged to compete with time-of-flight and quadrupole MS systems due to their higher ion transmissions and detector gains. Using the new CBM-EI, we demonstrate an instrument sensitivity increase of 20-fold to 100-fold relative to the CB-EI-equipped instrument. This remarkable signal increase by the simple addition of the magnet assembly arises from the magnet-induced gyromotion of the thermionic electrons, which vastly increases the effective path length of the electrons through the ionization region, and the collimated nature of the electron flux, which optimizes the ion transmission through the 100-{mu}m object slit of the MH-MS. Some or all of the realized sensitivity increase may be exchanged for an increase in resolution and/or mass range through the use of a narrower object slit, or for a reduction in ion-source pressure to limit quenching. The CBM-EI should facilitate development of a differentially pumped ion source to extend the lifetime of the filament, especially in otherwise intractable applications associated with oxidizing and corrosive samples.

Hadjar, O.; Fowler, W. K. [OI Analytical/CMS Field Products, 2148 Pelham Parkway, Bldg. 400, Pelham, Alabama 35124 (United States)

2012-06-15T23:59:59.000Z

173

Detection of triclocarban and two co-contaminating chlorocarbanilides in US aquatic environments using isotope dilution liquid chromatography tandem mass spectrometry  

SciTech Connect

The antimicrobial compound triclocarban (TCC; 3,4,4'-trichlorocarbanilide; CAS-bar 101-20-2) is a high-production-volume chemical, recently suggested to cause widespread contamination of US water resources. To test this hypothesis, we developed an isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry method for ultratrace analysis of TCC (0.9ng/L detection limit) and analyzed low-volume water samples (200mL) along with primary sludge samples from across the United States. All river water samples (100%) collected downstream of wastewater treatment plants had detectable levels of TCC, as compared to 56% of those taken upstream. Concentrations of TCC (mean+/-standard deviation) downstream of sewage treatment plants (84+/-110ng/L) were significantly higher (P<0.05; Wilcoxon rank sum test) than those of samples taken upstream (12+/-15ng/L). Compared to surface water, mean TCC concentrations found in dried, primary sludge obtained from municipal sewage treatment plants in five states were six orders of magnitude greater (19,300+/-7100{mu}g/kg). Several river samples contained a co-contaminant, identified based on its chromatographic retention time, molecular base ion, and MS/MS fragmentation behavior as 4,4'-dichlorocarbanilide (DCC; CAS-bar 1219-99-4). In addition to TCC and DCC, municipal sludge contained a second co-contaminant, 3,3',4,4'-tetrachlorocarbanilide (TetraCC; CAS-bar 4300-43-0). Both newly detected compounds were present as impurities (0.2%{sub w/w} each) in technical grade TCC (99%). Application of the new method for chlorocarbanilide analysis yielded TCC occurrence data for 13 US states, confirmed the role of sewage treatment plants as environmental inputs of TCC, and identified DCC and TetraCC as previously unrecognized pollutants released into the environment alongside TCC.

Sapkota, Amir [Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Johns Hopkins University Center for Water and Health, Baltimore, MD 21205-2103 (United States); Heidler, Jochen [Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Johns Hopkins University Center for Water and Health, Baltimore, MD 21205-2103 (United States); Halden, Rolf U. [Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Johns Hopkins University Center for Water and Health, Baltimore, MD 21205-2103 (United States)]. E-mail: rhalden@jhsph.edu

2007-01-15T23:59:59.000Z

174

Development of matrix assisted laser desorption ionization-ion mobility-orthogonal time-of-flight mass spectrometry as a tool for proteomics  

E-Print Network (OSTI)

Separations coupled to mass spectrometry (MS) are widely used for large-scale protein identification in order to reduce the adverse effects of analyte ion suppression, increase the dynamic range, and as a deconvolution technique for complex datasets typical of cellular protein complements. In this work, matrix assisted laser desorption-ionization is coupled with ion mobility (IM) separation for the analysis of biological molecules. The utility of liquid-phase separations coupled to MS lies in the orthogonality of the two separation dimensions for all analytes. The data presented in this work illustrates that IM-MS relies on the correlation between separation dimensions for different classes (either structural or chemical) of analyte ions to obtain a useful separation. For example, for a series of peptide ions of increasing mass-to-charge (m/z) a plot drift time in the IM drift cell vs. m/z increases in a near-linear fashion, but DNA or lipids having similar m/z values will have very different IM drift time-m/z relationships, thus drift time vs. m/z can be used as a qualitative tool for compound class identification. In addition, IM-MS is applied to the analysis of large peptide datasets in order to determine the peak capacity of the method for bottom-up experiments in proteomics, and it is found that IM separation increases the peak capacity of an MS-only experiment by a factor of 5-10. The population density of the appearance area for peptides is further characterized in terms of the gas-phase structural propensities for tryptic peptide ions. It is found that a small percentage (~3%) of peptide sequences form extended (i.e., helical or ?-sheet type) structures in the gas-phase, thus influencing the overall appearance area for peptide ions. Furthermore, the ability of IM-MS to screen for the presence of phosphopeptides is characterized, and it is found that post translationally modified peptides populate the bottom one-half to one-third of the total appearance area for peptide ions. In general, the data presented in this work indicates that IM-MS offers dynamic range and deconvolution capabilities comparable to liquid-phase separation techniques coupled to MS on a time scale (ms) that is fully compatible to current MS, including TOF-MS, technology.

Ruotolo, Brandon Thomas

2003-05-01T23:59:59.000Z

175

Quantification of absorption, retention and elimination of two different oral doses of vitamin A in Zambian boys using accelerator mass spectrometry  

SciTech Connect

A recent survey indicated that high-dose vitamin A supplements (HD-VAS) had no apparent effect on vitamin A (VA) status of Zambian children <5 y of age. To explore possible reasons for the lack of response to HD-VAS among Zambian children, we quantified the absorption, retention, and urinary elimination of either a single HDVAS (60 mg) or a smaller dose of stable isotope (SI)-labeled VA (5 mg), which was used to estimate VA pool size, in 3-4 y old Zambian boys (n = 4 for each VA dose). A 25 nCi tracer dose of [{sup 14}C{sub 2}]-labeled VA was co-administered with the HD-VAS or SI-labeled VA, and 24-hr stool and urine samples were collected for 3 and 7 consecutive days, respectively, and 24-hr urine samples at 4 later time points. Accelerator Mass Spectrometry (AMS) was used to measure the cumulative excretion of {sup 14}C in stool and urine 3d after dosing to estimate, respectively, absorption and retention of the VAS and SI-labeled VA. The urinary elimination rate (UER) was estimated by plotting {sup 14}C in urine vs. time, and fitting an exponential equation to the data. Estimates of mean absorption, retention and the UER were 83.8 {+-} 7.1%, 76.3 {+-} 6.7%, and 1.9 {+-} 0.6%/d, respectively, for the HD-VAS and 76.5 {+-} 9.5%, 71.1 {+-} 9.4%, and 1.8 {+-} 1.2%/d, respectively for the smaller dose of SI-labeled VA. Estimates of absorption, retention and the UER did not differ by size of the VA dose administered (P=0.26, 0.40, 0.88, respectively). Estimated absorption and retention were negatively associated with reported fever (P=0.011) and malaria (P =0.010). HD-VAS and SI-labeled VA were adequately absorbed, retained and utilized in apparently healthy Zambian preschool-age boys, although absorption and retention may be affected by recent infections.

Aklamati, E K; Mulenga, M; Dueker, S R; Buchholz, B A; Peerson, J M; Kafwembe, E; Brown, K H; Haskell, M J

2009-10-12T23:59:59.000Z

176

Synergistic use of Knudsen effusion quadrupole mass spectrometry, solid-state galvanic cell and differential scanning calorimetry for thermodynamic studies on lithium aluminates  

SciTech Connect

Three ternary oxides LiAl{sub 5}O{sub 8}(s), LiAlO{sub 2}(s) and Li{sub 5}AlO{sub 4}(s) in the system Li-Al-O were prepared by solid-state reaction route and characterized by X-ray powder diffraction method. Equilibrium partial pressure of CO{sub 2}(g) over the three-phase mixtures {l_brace}LiAl{sub 5}O{sub 8}(s)+Li{sub 2}CO{sub 3}(s)+5Al{sub 2}O{sub 3}(s){r_brace}, {l_brace}LiAl{sub 5}O{sub 8}(s)+5LiAlO{sub 2}(s)+2Li{sub 2}CO{sub 3}(s){r_brace} and {l_brace}LiAlO{sub 2}(s)+Li{sub 5}AlO{sub 4}(s)+2Li{sub 2}CO{sub 3}(s){r_brace} were measured using Knudsen effusion quadrupole mass spectrometry (KEQMS). Solid-state galvanic cell technique based on calcium fluoride electrolyte was used to determine the standard molar Gibbs energies of formations of these aluminates. The standard molar Gibbs energies of formation of these three aluminates calculated from KEQMS and galvanic cell measurements were in good agreement. Heat capacities of individual ternary oxides were measured from 127 to 868 K using differential scanning calorimetry. Thermodynamic tables representing the values of {delta}{sub f}H{sup 0}(298.15 K), S{sup 0}(298.15 K) S{sup 0}(T), C{sub p}{sup 0}(T), H{sup 0}(T), {l_brace}H{sup 0}(T)-H{sup 0}(298.15 K){r_brace}, G{sup 0}(T), {delta}{sub f}H{sup 0}(T), {delta}{sub f}G{sup 0}(T) and free energy function (fef) were constructed using second law analysis and FACTSAGE thermo-chemical database software. - Graphical abstract: Comparison of {delta}{sub f}G{sub m}{sup 0} of ternary oxides determined from KEQMS and solid-state galvanic cell techniques. (O) KEQMS, (9632;) solid-state galvanic cell and solid line: combined fit of both the experimental data.

Rakshit, S.K. [Product Development Section, Radiochemistry and Isotope Group, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India)], E-mail: swarupkr@barc.gov.in; Naik, Y.P.; Parida, S.C.; Dash, Smruti; Singh, Ziley; Sen, B.K.; Venugopal, V. [Product Development Section, Radiochemistry and Isotope Group, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India)

2008-06-15T23:59:59.000Z

177

Determination of the Tissue Distribution and Excretion by Accelerator Mass Spectrometry of the Nonadecapeptide 14C-Moli1901 in Beagle dogs after Intratracheal Instillation  

SciTech Connect

Administration of {sup 14}C-Moli1901 (duramycin, 2622U90), a 19 amino acid polycyclic peptide by intratracheal instillation (approximately 100 {micro}g) into the left cranial lobe of the lung of beagle dogs resulted in retention of 64% of the dose in the left cranial lobe for up to 28 days. In this study, we used accelerator mass spectrometry (AMS) to quantify Moli901 following administration of only 0.045 {micro}Ci of {sup 14}C-Moli901 per dog. Limits of quantitation of AMS were 0.03 (urine) to 0.3 (feces) ng equiv. Moli1901/g. Whole blood and plasma concentrations of {sup 14}C were <5ng/ml at all times after the dose. Concentrations of {sup 14}C in whole blood and plasma declined over the first day after the dose and rose thereafter, with the rise in plasma concentrations lagging behind those in whole blood. During the first 3 days after the dose, plasma accounted for the majority of {sup 14}C in whole blood, but after that time, plasma accounted for only 25-30% of the {sup 14}C in whole blood. Tissue (left and right caudal lung lobe, liver, kidney, spleen, brain) and bile concentrations were low, always less than 0.25% the concentrations found in the left cranial lung lobe. Approximately 13% of the dose was eliminated in urine and feces in 28 days, with fecal elimination accounting for about 10% of the dose. The data presented here are consistent with that obtained in other species. Moli1901 is slowly absorbed and excreted from the lung, and it does not accumulate in other tissues. Moli1901 is currently in the clinic and has proven to be safe in single dose studies in human volunteers and cystic fibrosis patients by the inhalation route. No information on the disposition of the compound in humans is available. This study in dogs demonstrates the feasibility of obtaining that information using {sup 14}C-Moli1901 and AMS.

Rickert, D E; Dingley, K H; Ubick, E; Dix, K J; Molina, L

2004-07-02T23:59:59.000Z

178

Development and analytical validation of a gas chromatography-mass spectrometry method for the assessment of gastrointestinal permeability and intestinal absorptive capacity in dogs  

E-Print Network (OSTI)

Assessment of gastrointestinal permeability in vivo is considered a suitable method for the evaluation of gastrointestinal mucosal integrity. Probes commonly used include lactulose (L) and rhamnose (R) for the assessment of intestinal permeability, xylose (X) and 3-O-methylglucose (M) for the evaluation of intestinal absorptive capacity, and sucrose (S) for the assessment of gastric permeability. Traditionally, various methods have been used to quantify these markers in the urine after orogastric administration. However, urine collection is difficult and uncomfortable. A protocol based on the analysis of blood samples would be easier to perform. Thus, the aim of the first part of this project was to develop and validate a new gas chromatography-mass spectrometry (GC-MS) method for the quantification of five sugar probes in canine serum. The method was sensitive, accurate, precise, and reproducible for the simultaneous quantification of 5 sugar probes in serum. The aim of the second part of this project was to assess the kinetic profiles of these 5 sugar probes in serum after orogastric administration in dogs and to determine the optimal time point for sample collection. Dogs received a solution containing L (10 g/L), R (10 g/L), X (10 g/L), M (5 g/L), and S (40 g/L) by orogastric intubation. Baseline blood samples were collected. Subsequent timed blood samples were taken for a 24 hours period. Significant changes in serum concentrations of all 5 sugars were detected after administration of the test dose (p<0.0001 for all 5 probes). Serum concentrations of L and R were significantly different from baseline concentrations from 90 to 240 and from 60 to 300 min post dosing respectively, and those of X, M, and S were significantly different from 30 to 240 min after dosing (p<0.05 for all 5 probes). Variations of the mean sugar concentrations of all dogs at 90, 120, and 180 minutes were analyzed using a Kruskal-Wallis test. Based on the results, only two blood samples, one taken at baseline and a second sample obtained between 90 and 180 after dosing, appear to be sufficient for assessment of intestinal permeability and mucosal absorptive capacity using these sugar probes.

Rodriguez Frausto, Heriberto

2008-12-01T23:59:59.000Z

179

Measurement of beam energy spectrum and impurity content in high-power neutral beam injectors  

DOE Green Energy (OSTI)

The energy spectrum and impurity content of a high-power neutral beam are measured by implanting the beam into high-purity silicon crystals. The depth distribution of the beam particles is then measured by secondary ion mass spectrometry (SIMS); the penetration depth is a function of the incident particle energy. This is one of the few measurement techniques that can determine neutral beam energy components directly. From the results, percentages of atomic and molecular ions in the source plasma can be inferred. Use of deuterium as the source gas provides insight into the role of residual hydrogen in the ion source and accelerating grids and in the SIMS analysis. The principal impurities are carbon and oxygen. Preliminary data indicate that carbon can originate from both methane and carbon monoxide, while oxygen can come from molecular oxygen, carbon monoxide, and water. Results are given and future plans are discussed.

Langley, R.A.; Ryan, P.M.; Tsai, C.C.; Menon, M.M.; Botnick, E.M.; Magee, C.W.

1985-05-01T23:59:59.000Z

180

Chemical nature of the passivation layer depending on the oxidizing agent in Gd2O3/GeO2/Ge stacks grown by molecular beam deposition  

Science Conference Proceedings (OSTI)

In Ge-based metal oxide semiconductor technology, the insertion of a passivation layer seems to be crucial in unpinning the Fermi level at the interface and in reducing the amount of interface defects. GeO"2 was obtained by atomic oxygen (AO), molecular ... Keywords: Gadolinium oxide, Germanium, Molecular beam deposition, Passivation layer, Time-of-flight secondary ion mass spectrometry

A. Lamperti; S. Baldovino; A. Molle; M. Fanciulli

2011-04-01T23:59:59.000Z

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181

Current developments in laser ablation-inductively coupled plasma-mass spectrometry for use in geology, forensics, and nuclear nonproliferation research  

SciTech Connect

This dissertation focused on new applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The diverse fields that were investigated show the versatility of the technique. In Chapter 2, LA-ICP-MS was used to investigate the rare earth element (REE) profiles of garnets from the Broken Hill Deposit in New South Wales, Australia. The normalized REE profiles helped to shed new light on the formation of deposits of sulfide ores. This information may be helpful in identifying the location of sulfide ore deposits in other locations. New sources of metals such as Pg, Zn, and Ag, produced from these ores, are needed to sustain our current technological society. The application of LA-ICP-MS presented in Chapter 3 is the forensics analysis of automotive putty and caulking. The elemental analysis of these materials was combined with the use of Principal Components Analysis (PCA). The PCA comparison was able to differentiate the automotive putty samples by manufacturer and lot number. The analysis of caulk was able to show a differentiation based on manufacturer, but no clear differentiation was shown by lot number. This differentiation may allow matching of evidence in the future. This will require many more analyses and the construction of a database made up of many different samples. The 4th chapter was a study of the capabilities of LA-ICP-MS for fast and precise analysis of particle ensembles for nuclear nonproliferation applications. Laser ablation has the ability to spatially resolve particle ensembles which may contain uranium or other actinides from other particles present in a sample. This is of importance in samples obtained from air on filter media. The particle ensembles of interest may be mixed in amongst dust and other particulates. A problem arises when ablating these particle ensembles directly from the filter media. Dust particles other than ones of interest may be accidentally entrained in the aerosol of the ablated particle ensemble. This would cause the analysis to be skewed. The use of a gelatin substrate allows the ablation a particle ensemble without disturbing other particles or the gelatin surface. A method to trap and ablate particles on filter paper using collodion was also investigated. The laser was used to dig through the collodion layer and into the particle ensemble. Both of these methods fix particles to allow spatial resolution of the particle ensembles. The use of vanillic acid as a possible enhancement to ablation was also studied. A vanillic acid coating of the particles fixed on top of the gelatin substrate was not found to have any positive effect on either signal intensity or precision. The mixing of vanillic acid in the collodion solution used to coat the filter paper increased ablation signal intensity by a factor of 4 to 5. There was little effect on precision, though. The collodion on filter paper method and the gelatin method of resolving particles have shown themselves to be possible tools in fighting proliferation of nuclear weapons and material. Future applications of LA-ICP-MS are only limited by the imagination of the investigator. Any material that can be ablated and aerosolized is a potential material for analysis by LA-ICP-MS. Improvements in aerosol transport, ablation chamber design, and laser focusing can make possible the ablation and analysis of very small amounts of material. This may perhaps lead to more possible uses in forensics. A similar method to the one used in Chapter 3 could perhaps be used to match drug residue to the place of origin. Perhaps a link could be made based on the elements leached from the soil by plants used to make drugs. This may have a specific pattern based on where the plant was grown. Synthetic drugs are produced in clandestine laboratories that are often times very dirty. The dust, debris, and unique materials in the lab environment could create enough variance to perhaps match drugs produced there to samples obtained off the street. Even if the match was not strong enough to be evidence, the knowledge that many sa

Messerly, Joshua D.

2008-08-26T23:59:59.000Z

182

Airfoil sampling of a pulsed Laval beam with tunable vacuum ultraviolet (VUV) synchrotron ionization quadrupole mass spectrometry: Application to low--temperature kinetics and product detection  

E-Print Network (OSTI)

flows suitable for kinetic studies of chemical reactions infor a chemical reaction in the available kinetic window ofa complex kinetic behavior. The rate of chemical reactions

Soorkia, Satchin

2012-01-01T23:59:59.000Z

183

Compact hydrogen/helium isotope mass spectrometer  

DOE Patents (OSTI)

The compact hydrogen and helium isotope mass spectrometer of the present invention combines low mass-resolution ion mass spectrometry and beam-foil interaction technology to unambiguously detect and quantify deuterium (D), tritium (T), hydrogen molecule (H.sub.2, HD, D.sub.2, HT, DT, and T.sub.2), .sup.3 He, and .sup.4 He concentrations and concentration variations. The spectrometer provides real-time, high sensitivity, and high accuracy measurements. Currently, no fieldable D or molecular speciation detectors exist. Furthermore, the present spectrometer has a significant advantage over traditional T detectors: no confusion of the measurements by other beta-emitters, and complete separation of atomic and molecular species of equivalent atomic mass (e.g., HD and .sup.3 He).

Funsten, Herbert O. (Los Alamos, NM); McComas, David J. (Los Alamos, NM); Scime, Earl E. (Morgantown, WV)

1996-01-01T23:59:59.000Z

184

Mexico City Aerosol Analysis During Milagro Using High Resolution Aerosol Mass Spectrometry at the Urban Supersite (T0) - Part 1: Fine Particle Composition and Organic Source Apportionment.  

E-Print Network (OSTI)

Submicron aerosol was analyzed during the MILAGRO field campaign in March 2006 at the T0 urban supersite in Mexico City with a High-Resolution Aerosol Mass Spectrometer (AMS) and complementary instrumentation. Positive ...

Aiken, A. C.

185

Decomposition of NH3BH3 at sub-ambient pressures: A combined thermogravimetry-differential thermal analysis-mass spectrometry study  

DOE Green Energy (OSTI)

We report a systematic study of the isothermal decomposition of ammonia borane, NH3BH3, at 363 K as a function of argon pressure ranging between 50 and 1040 mbar using thermogravimetry and differential thermal analysis coupled with mass analysis of the volatile species. During thermal aging at 363 K, evolution of hydrogen, aminoborane and borazine is monitored, with the relative mass loss strongly depending on the pressure in the reaction chamber. Furthermore, the induction period required for hydrogen release at 363 K decreases with decreasing pressure.

Palumbo, Oriele; Paolone, Annalisa; Rispoli, Pasquale; Cantelli, Rosario; Autrey, Thomas

2010-03-15T23:59:59.000Z

186

New constraints on methane fluxes and rates of anaerobic methane oxidation in a Gulf of Mexico brine pool via in situ mass spectrometry  

E-Print Network (OSTI)

New constraints on methane fluxes and rates of anaerobic methane oxidation in a Gulf of Mexico Keywords: Methane flux Mass spectrometer Brine pool Methane oxidation Gulf of Mexico a b s t r a c t Deep report direct measurements of methane concentrations made in a Gulf of Mexico brine pool located

Girguis, Peter R.

187

High-Throughput Proteomics Using High Efficiency Multiple-Capillary Liquid Chromatography With On-Line High-Performance ESI FTICR Mass Spectrometry  

Science Conference Proceedings (OSTI)

We report on the design and application of a high-efficiency multiple-capillary liquid chromatography (LC) system for high-throughput proteome analysis. The multiple-capillary LC system was operated at the pressure of 10,000 psi using commercial LC pumps to deliver the mobile phase and newly developed passive feedback valves to switch the mobile phase flow and introduce samples. The multiple-capillary LC system was composed of several serially connected dual-capillary column devices. The dual-capillary column approach was designed to eliminate the time delay for regeneration (or equilibrium) of the capillary column after its use under the mobile phase gradient condition (i.e. one capillary column was used in separation and the other was washed using mobile phase A). The serially connected dual-capillary columns and ESI sources were operated independently, and could be used for either''backup'' operation or with other mass spectrometer(s). This high-efficiency multiple-capillary LC system uses switching valves for all operations and is highly amenable to automation. The separations efficiency of dual-capillary column device, optimal capillary dimensions (column length and packed particle size), suitable mobile phases for electrospray, and the capillary re-generation were investigated. A high magnetic field (11.5 tesla) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer was coupled on-line with this high-efficiency multiple-capillary LC system through an electrospray ionization source. The capillary LC provided a peak capacity of {approx}600, and the 2-D capillary LC-FTICR provided a combined resolving power of > 6 x 10 7 polypeptide isotopic distributions. For yeast cellular tryptic digests, > 100,000 polypeptides were typically detected, and {approx}1,000 proteins can be characterized in a single run.

Shen, Yufeng (BATTELLE (PACIFIC NW LAB)); Tolic, Nikola (BATTELLE (PACIFIC NW LAB)); Zhao, Rui (ASSOC WESTERN UNIVERSITY); Pasa Tolic, Ljiljana (BATTELLE (PACIFIC NW LAB)); Li, Lingjun (Illinois Univ Of-Urbana/Champa); Berger, Scott J. (ASSOC WESTERN UNIVERSITY); Harkewicz, Richard (BATTELLE (PACIFIC NW LAB)); Anderson, Gordon A. (BATTELLE (PACIFIC NW LAB)); Belov, Mikhail E. (BATTELLE (PACIFIC NW LAB)); Smith, Richard D. (BATTELLE (PACIFIC NW LAB))

2000-12-01T23:59:59.000Z

188

Beam History  

NLE Websites -- All DOE Office Websites (Extended Search)

Beam Status Beam History Print Beamline History Request Form To request a beam current histograph from the ALS storage ring beam histograph database, select the year, month, and...

189

Accurate determination of Curium and Californium isotopic ratios by inductively coupled plasma quadrupole mass spectrometry (ICP-QMS) in 248Cm samples for transmutation studies  

Science Conference Proceedings (OSTI)

The French Atomic Energy Commission has carried out several experiments including the mini-INCA (INcineration of Actinides) project for the study of minor-actinide transmutation processes in high intensity thermal neutron fluxes, in view of proposing solutions to reduce the radiotoxicity of long-lived nuclear wastes. In this context, a Cm sample enriched in {sup 248}Cm ({approx}97 %) was irradiated in thermal neutron flux at the High Flux Reactor (HFR) of the Laue-Langevin Institute (ILL). This work describes a quadrupole ICP-MS (ICP-QMS) analytical procedure for precise and accurate isotopic composition determination of Cm before sample irradiation and of Cm and Cf after sample irradiation. The factors that affect the accuracy and reproducibility of isotopic ratio measurements by ICP-QMS, such as peak centre correction, detector dead time, mass bias, abundance sensitivity and hydrides formation, instrumental background, and memory blank were carefully evaluated and corrected. Uncertainties of the isotopic ratios, taking into account internal precision of isotope ratio measurements, peak tailing, and hydrides formations ranged from 0.3% to 1.3%. This uncertainties range is quite acceptable for the nuclear data to be used in transmutation studies.

Gourgiotis, A.; Isnard, H.; Aubert, M.; Dupont, E.; AlMahamid, I.; Cassette, P.; Panebianco, S.; Letourneau, A.; Chartier, F.; Tian, G.; Rao, L.; Lukens, W.

2011-02-01T23:59:59.000Z

190

Nuclear Masses in Astrophysics  

E-Print Network (OSTI)

Among all nuclear ground-state properties, atomic masses are highly specific for each particular combination of N and Z and the data obtained apply to a variety of physics topics. One of the most crucial questions to be addressed in mass spectrometry of unstable radionuclides is the one of understanding the processes of element formation in the Universe. To this end, accurate atomic mass values of a large number of exotic nuclei participating in nucleosynthesis are among the key input data in large-scale reaction network calculations. In this paper, a review on the latest achievements in mass spectrometry for nuclear astrophysics is given.

Christine Weber; Klaus Blaum; Hendrik Schatz

2008-12-09T23:59:59.000Z

191

The use of a high intensity neutrino beam from the ESS proton linac for measurement of neutrino CP violation and mass hierarchy  

E-Print Network (OSTI)

It is proposed to complement the ESS proton linac with equipment that would enable the production, concurrently with the production of the planned ESS beam used for neutron production, of a 5 MW beam of 10$^{23}$ 2.5 GeV protons per year in microsecond short pulses to produce a neutrino Super Beam, and to install a megaton underground water Cherenkov detector in a mine to detect $\

E. Baussan; M. Dracos; T. Ekelof; E. Fernandez Martinez; H. Ohman; N. Vassilopoulos

2012-12-20T23:59:59.000Z

192

3D Molecular Bioimaging Mass Spectrometry  

Science Conference Proceedings (OSTI)

... ion images as a function of increasing depth during dynamic SIMS sputtering of ... used which in turn allows for higher sputtering rates, faster analysis ...

2012-10-02T23:59:59.000Z

193

Improving gene annotation using peptide mass spectrometry  

E-Print Network (OSTI)

Tanner, Zhouxin Shen, Julio Ng, Liliana Florea, Roderic1,6 Zhouxin Shen, 2 Julio Ng, 1 Liliana Florea, 3 Roderic

2007-01-01T23:59:59.000Z

194

CAMS Center for Accelerator Mass Spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

research Lichen research Dinosaur bone research Biology Earth Science About CAMS Tour CAMS History of CAMS Meet the CAMS Staff CAMS Publications CAMS Home Seminars Download...

195

Improved Ambient Ionization Source for Mass Spectrometry ...  

Pacific Northwest National Laboratory Skip to Main Content U.S. Department of Energy. Search PNNL. PNNL Home; About; Research; Publications; Jobs; ...

196

Beam History  

NLE Websites -- All DOE Office Websites (Extended Search)

Beam History Print Beamline History Request Form To request a beam current histograph from the ALS storage ring beam histograph database, select the year, month, and day, then...

197

Catalytic Steam Reforming of Gasifier Tars: On-Line Monitoring of Tars with a Transportable Molecular-Beam Mass Spectrometer; Milestone Completion Report  

DOE Green Energy (OSTI)

A method for evaluating catalytic tar decomposition in real time is presented. The effectiveness of two catalysts are compared. A key technical and economic barrier to commercialization of biomass gasification technologies is the removal of tars that are unavoidably formed in this thermochemical process. Tars contain fuel value; however, they are problematic in gas engines (both reciprocating and turbine) because they condense in the fuel delivery system, forming deposits that negatively affect operation and efficiency. These tars also combust with high luminosity, potentially forming soot particles. The conventional technology for tar removal is wet scrubbing. Although this approach has shown some success, there are significant equipment and operating costs associated with it. In order to prevent the generation of toxic wastewater, the tars must be separated and either disposed as hazardous waste or, preferably, combusted in the gasification plant. A conceptually better approach is catalytic steam reforming of the tars to hydrogen and carbon monoxide (CO), effectively increasing the gasification efficiency and eliminating the problems mentioned above. In FY2000, Battelle Columbus Laboratories attempted to demonstrate integrated gasification-gas turbine operation using catalytic steam reforming of tars. NREL participated in those tests using the transportable molecular-beam mass spectrometer (TMBMS) to monitor the catalytic reactor's performance on-line [10]. Unfortunately, the pilot plant tests encountered operational problems that prevented conclusive determination of the efficacy of the selected catalyst (Battelle's DN34). In FY2001, NREL performed on-site tar steam reforming tests using a slip-stream of hot pyrolysis gas from the Thermochemical Process Development Unit (TCPDU), which was directed to a bench-scale fluidized bed reactor system designed expressly for this purpose. Supporting this effort, the TMBMS was employed to provide on-line analysis of the tar conversion. The gas composition changes were monitored by two identical gas chromatographs (GCs), and modified method 5 sampling was performed to obtain gravimetric conversion data. The combination of these analytical techniques provided definitive catalyst performance data, as well as linkage to previous and on-going work elsewhere. Two catalysts were tested: nickel (Ni) on potassium promoted alumina (Sued-Chemie C11-NK), used commercially for naphtha steam reforming, and alumina (Battelle's DN34) claimed to be effective for gasifier tar decomposition. In addition, sand was tested as an inert reference material.

Carpenter, D.; Ratcliff, M.; Dayton, D.

2002-05-01T23:59:59.000Z

198

Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure  

DOE Patents (OSTI)

The invention discloses a new interface with non-circular conductance limit aperture(s) useful for effective transmission of non-circular ion beams between stages with different gas pressure. In particular, the invention provides an improved coupling of field asymmetric waveform ion mobility spectrometry (FAIMS) analyzers of planar or side-to-side geometry to downstream stages such as mass spectrometry or ion mobility spectrometry. In this case, the non-circular aperture is rectangular; other geometries may be optimum in other applications. In the preferred embodiment, the non-circular aperture interface is followed by an electrodynamic ion funnel that may focus wide ion beams of any shape into tight circular beams with virtually no losses. The jet disrupter element of the funnel may also have a non-circular geometry, matching the shape of arriving ion beam. The improved sensitivity of planar FAIMS/MS has been demonstrated in experiments using a non-contiguous elongated aperture but other embodiments (e.g., with a contiguous slit aperture) may be preferable, especially in conjunction with an ion funnel operated at high pressures.

Tang, Keqi (Richland, WA); Shvartsburg, Alexandre A. (Richland, WA); Smith, Richard D. (Richland, WA)

2008-03-04T23:59:59.000Z

199

Investigation of the effect of intra-molecular interactions on the gas-phase conformation of peptides as probed by ion mobility-mass spectrometry, gas-phase hydrogen/deuterium exchange, and molecular mechanics  

E-Print Network (OSTI)

Ion mobility-mass spectrometry (IM-MS), gas-phase hydrogen/deuterium (H/D) exchange ion molecule reactions and molecular modeling provide complimentary information and are used here for the characterization of peptide ion structure, including fine structure detail (i.e., cation-? interactions, ?-turns, and charge solvation interactions). IM-MS experiments performed on tyrosine containing tripeptides show that the collision cross-sections of sodiated, potassiated and doubly sodiated species of gly-gly-tyr are smaller than that of the protonated species, while the cesiated and doubly cesiated species are larger. Conversely, all of the alkali-adducted species of try-gly-gly have collision cross-sections that are larger than that of the protonated species. The protonated and alkali metal ion adducted (Na+, K+ and Cs+) species of bradykinin and bradykinin fragments 1-5, 1-6, 1-7, 1-8, 2-7, 5-9 and 2-9 were also studied using IM-MS and the alkali metal ion adducts of these species were found to have cross-sections very close to those of the protonated species. Additionally, multiple peak features observed in the ATDs of protonated bradykinin fragments 1-5, 1-6 and 1-7 are conserved upon alkali metal ion adduction. It was observed from gas-phase H/D ion molecule reactions that alkali adducted species exchange slower and to a lesser extent than protonated species in the tyrosine- and arginine-containing peptides. Experimental and computational results are discussed in terms of peptide ion structure, specifically the intra-molecular interactions present how those interactions change upon alkali salt adduction, as well as with the sequence of the peptide. Additionally, IM-MS data suggests the presence of a compact conformation of bradykinin fragment 1-5 (RPPGF) when starting from organic solvent conditions. As water is added stepwise to methanolic solutions, a more extended conformation is populated. When the starting solution is composed of ?90% water, two distinct mobility profiles are observed as well as a shoulder, indicating the presence of three gas-phase conformations for RPPGF. Gas-phase H/D exchange of [M+H]+ ions prepared from aqueous solvents show a bi-exponential decay, whereas samples prepared from organic solvents show a single exponential decay. The effect of solvent on gas-phase peptide ion structure, i.e., solution-phase memory effects, is discussed and gas-phase structures are compared to know solution-phase structures.

Sawyer, Holly Ann

2004-12-01T23:59:59.000Z

200

JOURNAL OF MASS SPECTROMETRY J. Mass Spectrom. 2008; 43: 11611180  

E-Print Network (OSTI)

the rapid addition of energy to a condensed-phase sample (e.g. heat, photons, droplet or gas impact) results/ionization techniques in use with MS (Fig. 1). Introduced in the mid-1970s, commercially available in the 1980s. In this approach to surface sampling, heat is used to liberate the sample intact from the condensed phase

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201

Heat and mass transfer in a gas in a capillary induced by light with nonuniform intensity distribution over the beam cross section  

SciTech Connect

An analysis is presented of the heat and drift fluxes induced by velocity-selective light absorption in a single-component gas in a capillary tube. The light intensity distribution across the beam is assumed to have a Gaussian profile. Kinetic equations are solved numerically to calculate flux profiles and kinetic coefficients quantifying the contributions of surface and collisional mechanisms to light-induced transfer as functions of the Knudsen number, the ratio of the rate of radiative decay of the exited level and intermolecular collision frequency, accommodation coefficient, and the ratio of the tube radius to the light beam radius.

Chernyak, V. G., E-mail: vladimir.chernyak@usu.ru; Polikarpov, A. P., E-mail: alexey.polikarpov@usu.ru [Ural State University (Russian Federation)

2011-01-15T23:59:59.000Z

202

Activation Measurements for Thermal Neutrons, U.S. Measurements of 36Cl in Mineral Samples from Hiroshima and Nagasaki; and Measurement of 63 Ni in Copper Samples From Hiroshima by Accelerator Mass Spectrometry  

SciTech Connect

The present paper presents the {sup 36}Cl measurement effort in the US. A large number of {sup 36}Cl measurements have been made in both granite and concrete samples obtained from various locations and distances in Hiroshima and Nagasaki. These measurements employed accelerator mass spectrometry (AMS) to quantify the number of atoms of {sup 36}Cl per atom of total Cl in the sample. Results from these measurements are presented here and discussed in the context of the DS02 dosimetry reevaluation effort for Hiroshima and Nagasaki atomic-bomb survivors. The production of {sup 36}Cl by bomb neutrons in mineral samples from Hiroshima and Nagasaki was primarily via the reaction {sup 35}Cl(n,{gamma}){sup 36}Cl. This reaction has a substantial thermal neutron cross-section (43.6 b at 0.025 eV) and the product has a long half-life (301,000 y). hence, it is well suited for neutron-activation detection in Hiroshima and Nagasaki using AMS more than 50 years after the bombings. A less important reaction for bomb neutrons, {sup 39}K(n,{alpha}){sup 36}Cl, typically produces less than 10% of the {sup 36}Cl in mineral samples such as granite and concrete, which contain {approx} 2% potassium. In 1988, only a year after the publication of the DS86 final report (Roesch 1987), it was demonstrated experimentally that {sup 36}Cl measured using AMS should be able to detect the thermal neutron fluences at the large distances most relevant to the A-bomb survivor dosimetry. Subsequent measurements in mineral samples from both Hiroshima and Nagasaki validated the experimental findings. The potential utility of {sup 36}Cl as a thermal neutron detector in Hiroshima was first presented by Haberstock et al. who employed the Munich AMS facility to measure {sup 36}Cl/Cl ratios in a gravestone from near the hypocenter. That work subsequently resulted in an expanded {sup 36}Cl effort in Germany that paralleled the US work. More recently, there have also been {sup 36}Cl measurements made by a Japanese group. The impetus for the extensive {sup 36}Cl and other neutron activation measurements was the recognized need to validate the neutron component of the dose in Hiroshima. Although this was suggested at the time of the DS86 Final Report, where it was stated that the calculated neutron doses for survivors could possibly be wrong, the paucity of neutron validation measurements available at that time prevented adequate resolution of this matter. It was not until additional measurements and data evaluations were made that it became clear that more work was required to better understand the discrepancies observed for thermal neutrons in Hiroshima. This resulted in a large number of additional neutron activation measurements in Hiroshima and Nagasaki by scientists in the US, Japan, and Germany. The results presented here for {sup 36}Cl, together with measurements made by other scientists and for other isotopes, now provide a much improved measurement basis for the validation of neutrons in Hiroshima.

Tore Straume; Alfredo A. Marchetti; Stephen D. Egbert; James A. Roberts; Ping Men; Shoichiro Fujita; Kiyoshi Shizuma; Masaharu Hoshi; G. Rugel; W. Ruhm; G. Korschinek; J. E. McAninch; K. L. Carroll; T. Faestermann; K. Knie; R. E. Martinelli; A. Wallner; C. Wallner

2005-01-14T23:59:59.000Z

203

A backscattering spectrometry device for identifying unknown elements present in a workpiece  

DOE Patents (OSTI)

This invention is comprised of a backscattering spectrometry method and device for identifying and quantifying impurities in a workpiece during processing and manufacturing of that workpiece. While the workpiece is implanted with an ion beam, that same ion beam backscatters resulting from collisions with known atoms and with impurities within the workpiece. Those ions backscatter along a predetermined scattering angle and are filtered using a self-supporting filter to stop the ions with a lower energy because they collided with the known atoms of the workpiece of a smaller mass. Those ions which pass through the filter have a greater energy resulting from impact with impurities having a greater mass than the known atoms of the workpiece. A detector counts the number and measures the energy of the ions which pass through the filter. From the energy determination and knowledge of the scattering angle, a mass calculation determines the identity, and from the number and solid angle of the scattering angle, a relative concentration of the impurity is obtained.

Doyle, B.L.; Knapp, J.A.

1990-12-31T23:59:59.000Z

204

Resolving Emissions Dynamics via Mass Spectrometry: Time Resolved Measurements of Emission Transients by Mass Spectrometry  

DOE Green Energy (OSTI)

Transient emissions occur throughout normal engine operation and can significantly contribute to overall system emissions. Such transient emissions may originate from various sources including cold start, varying load and exhaust-gas recirculation (EGR) rates; all of which are dynamic processes in the majority of engine operation applications (1). Alternatively, there are systems which are inherently dynamic even at steady-state engine-operation conditions. Such systems include catalytic exhaust-emissions treatment devices with self-initiated and sustained oscillations (2) and NOX adsorber systems (3,4,5). High-speed diagnostics, capable of temporally resolving such emissions transients, are required to characterize the process, verify calculated system inputs, and optimize the system.

Partridge, William P.

2000-08-20T23:59:59.000Z

205

Initial measurement of impurity production and hydrogen energy distribution from neutral beam injectors  

DOE Green Energy (OSTI)

Impurity production and hydrogen energy distributions for neutral beam injectors (NBI) developed by the plasma Technology Section of Oak Ridge National Laboratory's (ORNL's) Fusion Energy Division have been measured by exposing silicon samples to beam pulses and analyzing them by nuclear microanalysis and secondary ion mass spectrometry (SIMS) techniques. The NBI's have been developed for use on the princeton Large Torus (PLT), the Poloidal Divertor Experiment (PDX), and the Impurity Study Experiment (ISX). Extraction voltages O up to 50 kV are used, and maximum power injected for a 0.5-s pulse is approx. 1.2 MW with a design goal of 1.5 MW. The Medium Energy Test Facility (MRTF) was used for exposure of the single-crystal (100) silicon samples.

Langley, R.A.; Magee, C.W.

1980-01-01T23:59:59.000Z

206

Sandia National Labs: PCNSC: Heavy Ion Backscattering Spectrometry  

NLE Websites -- All DOE Office Websites (Extended Search)

Heavy Ion Backscattering Spectrometry (HIBS) Heavy Ion Backscattering Spectrometry (HIBS) IBA Table (HTML) | IBA Table (135KB GIF) | IBA Table (1.2MB PDF) | IBA Table (33MB TIF) | Heavy Ion Backscattering Spectrometry (HIBS) | Virtual Lab Tour (6MB) Description of Technique: HIBS is used to detect ultra-trace levels of heavy impurities on the surface of a Si wafer. HIBS has advantages over TXRF, including: Improved sensitivity for most elements Quantifying composition without standards Measurement on rough surfaces. HIBS is accomplished by focusing a 120 keV beam of C+ions onto a small spot at the wafer's surface. The backscattered ions are collected by a time-of-flight (TOF) detector array with a large solid angle. The flight time of the backscattered C identifies the near-surface impurities and the

207

Increasing Confidence of LC-MS Identifications by Utilizing Ion Mobility Spectrometry  

SciTech Connect

Ion mobility spectrometry in conjunction with liquid chromatography separations and mass spectrometry offers a range of new possibilities for analyzing complex biological samples. To fully utilize the information obtained from these three measurement dimensions, informatics tools based on the accurate mass and time tag methodology were modified to incorporate ion mobility spectrometry drift times for peptides observed in human serum. A reference human serum database was created using 12,139 peptides, tracking the monoisotopic mass, liquid chromatography normalized elution time, and ion mobility spectrometry drift time(s) for each peptide. We demonstrate that the use of three dimensions for peak matching during the peptide identification process resulted in increased numbers of identifications and lower false discovery rates relative to the use of only the mass and normalized elution time dimensions.

Crowell, Kevin L.; Baker, Erin Shammel; Payne, Samuel H.; Ibrahim, Yehia M.; Monroe, Matthew E.; Slysz, Gordon W.; Lamarche, Brian L.; Petyuk, Vladislav A.; Piehowski, Paul D.; Danielson, William F.; Anderson, Gordon A.; Smith, Richard D.

2013-09-05T23:59:59.000Z

208

Microchip and wedge ion funnels and planar ion beam analyzers using same  

DOE Patents (OSTI)

Electrodynamic ion funnels confine, guide, or focus ions in gases using the Dehmelt potential of oscillatory electric field. New funnel designs operating at or close to atmospheric gas pressure are described. Effective ion focusing at such pressures is enabled by fields of extreme amplitude and frequency, allowed in microscopic gaps that have much higher electrical breakdown thresholds in any gas than the macroscopic gaps of present funnels. The new microscopic-gap funnels are useful for interfacing atmospheric-pressure ionization sources to mass spectrometry (MS) and ion mobility separation (IMS) stages including differential IMS or FAIMS, as well as IMS and MS stages in various configurations. In particular, "wedge" funnels comprising two planar surfaces positioned at an angle and wedge funnel traps derived therefrom can compress ion beams in one dimension, producing narrow belt-shaped beams and laterally elongated cuboid packets. This beam profile reduces the ion density and thus space-charge effects, mitigating the adverse impact thereof on the resolving power, measurement accuracy, and dynamic range of MS and IMS analyzers, while a greater overlap with coplanar light or particle beams can benefit spectroscopic methods.

Shvartsburg, Alexandre A; Anderson, Gordon A; Smith, Richard D

2012-10-30T23:59:59.000Z

209

Compact time-of-flight mass spectrometer  

SciTech Connect

This paper describes a time-of-flight mass spectrometer developed for measuring the parameters of a pulsed hydrogen beam. The duration of an electron-beam current pulse in the ionizer of the mass spectrometer can be varied within 2-20 usec, the pulse electron current is 0.6 mA, and the electron energy is 250 eV. The time resolution of the mass spectrometer is determined by the repetition period of the electron-beam current pulses and is 40 usec. The mass spectrometer has 100% transmission in the direction of motion of molecular-beam particles. The dimension of the mass spectrometer is 7 cm in this direction. The mass resolution is sufficient for determination of the composition of the hydrogen beam.

Belov, A.S.; Kubalov, S.A.; Kuzik, V.F.; Yakushev, V.P.

1986-02-01T23:59:59.000Z

210

Spectrometry of X-Ray Beams Used for Calibrations  

Science Conference Proceedings (OSTI)

... and used to calibrate a wavelength-dispersive crystal x-ray spectrograph used by Lawrence Livermore National Laboratory (LLNL) to diagnose ...

2012-06-26T23:59:59.000Z

211

Differential auger spectrometry  

DOE Patents (OSTI)

Differential Auger spectroscopy method for increasing the sensitivity of micro-Auger spectroanalysis of the surfaces of dilute alloys, by alternately periodically switching an electron beam back and forth between an impurity free reference sample and a test sample containing a trace impurity. The Auger electrons from the samples produce representative Auger spectrum signals which cancel to produce an Auger test sample signal corresponding to the amount of the impurity in the test samples.

Strongin, Myron (Center Moriches, NY); Varma, Matesh Narayan (Shirley, NY); Anne, Joshi (St. Louis Park, MN)

1976-06-22T23:59:59.000Z

212

A support vector machine model for the prediction of proteotypic peptides for accurate mass and time proteomics  

Science Conference Proceedings (OSTI)

Motivation: The standard approach to identifying peptides based on accurate mass and elution time (AMT) compares profiles obtained from a high resolution mass spectrometer to a database of peptides previously identified from tandem mass spectrometry ...

Bobbie-Jo M. Webb-Robertson; William R. Cannon; Christopher S. Oehmen; Anuj R. Shah; Vidhya Gurumoorthi; Mary S. Lipton; Katrina M. Waters

2010-07-01T23:59:59.000Z

213

A support vector machine model for the prediction of proteotypic peptides for accurate mass and time proteomics  

Science Conference Proceedings (OSTI)

Motivation: The standard approach to identifying peptides based on accurate mass and elution time (AMT) compares profiles obtained from a high resolution mass spectrometer to a database of peptides previously identified from tandem mass spectrometry ...

Bobbie-Jo M. Webb-Robertson; William R. Cannon; Christopher S. Oehmen; Anuj R. Shah; Vidhya Gurumoorthi; Mary S. Lipton; Katrina M. Waters

2008-07-01T23:59:59.000Z

214

The History of Nuclidic Masses and of their Evaluation  

E-Print Network (OSTI)

This paper is centered on some historical aspects of nuclear masses, and their relations to major discoveries. Besides nuclear reactions and decays, the heart of mass measurements lies in mass spectrometry, the early history of which will be reviewed first. I shall then give a short history of the mass unit which has not always been defined as one twelfth of the carbon-12 mass. When combining inertial masses from mass spectrometry with energy differences obtained in reactions and decays, the conversion factor between the two is essential. The history of the evaluation of the nuclear masses (actually atomic masses) is only slightly younger than that of the mass measurements themselves. In their modern form, mass evaluations can be traced back to 1955. Prior to 1955, several tables were established, the oldest one in 1935.

G. Audi

2006-02-08T23:59:59.000Z

215

Surface science analysis of GaAs photocathodes following sustained electron beam delivery  

DOE Green Energy (OSTI)

Degradation of the photocathode materials employed in photoinjectors represents a challenge for sustained operation of nuclear physics accelerators and high power Free Electron Lasers (FEL). Photocathode quantum efficiency (QE) degradation is due to residual gasses in the electron source vacuum system being ionized and accelerated back to the photocathode. These investigations are a first attempt to characterize the nature of the photocathode degradation, and employ multiple surface and bulk analysis techniques to investigate damage mechanisms including sputtering of the Cs-oxidant surface monolayer, other surface chemistry effects, and ion implantation. Surface and bulk analysis studies were conducted on two GaAs photocathodes, which were removed from the JLab FEL DC photoemission gun after delivering electron beam, and two control samples. The analysis techniques include Helium Ion Microscopy (HIM), Rutherford Backscattering Spectrometry (RBS), Atomic Force Microscopy (AFM) and Secondary Ion Mass Spectrometry (SIMS). In addition, two high-polarization strained superlattice GaAs photocathode samples, one removed from the Continuous Electron Beam Accelerator Facility (CEBAF) photoinjector and one unused, were also analyzed using Transmission Electron Microscopy (TEM) and SIMS. It was found that heat cleaning the FEL GaAs wafer introduces surface roughness, which seems to be reduced by prolonged use. The bulk GaAs samples retained a fairly well organized crystalline structure after delivering beam but shows evidence of Cs depletion on the surface. Within the precision of the SIMS and RBS measurements the data showed no indication of hydrogen implantation or lattice damage from ion back bombardment in the bulk GaAs wafers. In contrast, SIMS and TEM measurements of the strained superlattice photocathode show clear crystal damage in the wafer from ion back bombardment.

Carlos Hernandez-Garcia, Fay Hannon, Marcy Stutzman, V. Shutthanandan, Z. Zhu, M. Nandasri, S. V. Kuchibhatla, S. Thevuthasan, W. P. Hess

2012-06-01T23:59:59.000Z

216

BEAM LINE  

NLE Websites -- All DOE Office Websites (Extended Search)

BEAM LINE BEAM LINE 45 W ILHELM ROENTGEN'S INITIAL DISCOVERY of X-radiation in 1895 led immediately to practical applications in medicine. Over the next few decades X rays proved to be an invaluable tool for the investigation of the micro-world of the atom and the development of the quantum theory of matter. Almost a century later, telescopes designed to detect X-radiation are indispensable for understanding the structure and evolution of the macro-world of stars, galaxies, and the Universe as a whole. The X-Ray Universe by WALLACE H. TUCKER X-ray images of the Universe are strikingly different from the usual visible-light images. 46 SUMMER 1995 did not think: I investigated." Undeterred by NASA's rejection of a proposal to search for cosmic X-radiation, Giacconi persuaded the

217

Accelerator beam profile analyzer  

DOE Patents (OSTI)

A beam profile analyzer employing sector or quadrant plates each servo controlled to outline the edge of a beam.

Godel, Julius B. (Bayport, NY); Guillaume, Marcel (Grivegnee, BE); Lambrecht, Richard M. (East Quogue, NY); Withnell, Ronald (East Setauket, NY)

1976-01-01T23:59:59.000Z

218

Mass Spectrometry of Synthetic-Polymer Mixtures Workshop  

Science Conference Proceedings (OSTI)

... is held at constant total energy), changes in ... combining his continuum model theory with molecular ... than that found by nuclear magnetic resonance. ...

2013-09-30T23:59:59.000Z

219

OBT Measurement of Vegetation by Mass Spectrometry and Radiometry  

Science Conference Proceedings (OSTI)

Environmental and Organically Bound Tritium / Proceedings of the Ninth International Conference on Tritium Science and Technology (Part 2)

T. Tamari; H. Kakiuchi; N. Momoshima; N. Baglan; S. Sugihara; T. Uda

220

High-Sensitivity Ion Mobility Spectrometry/Mass ...  

... Bowers, M. T.; Kemper, P. R.; von Helden, G.; van Koppen, P. A. M. Science 1993, 260, 1446 ... (£), which results in large ion ... and R d is the ...

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Quantification of neptunium by isotope dilution mass spectrometry  

SciTech Connect

A surface ionization-diffusion-type ionization source that uses a rhenium filament overplated with platinum has been developed and optimized for 0.1-ng neptunium samples. This source is capable of measuring the neptunium content of nuclear-test-debris samples to 0.15% precision at the 95% confidence level. 14 refs., 3 figs., 3 tabs.

Efurd, D.W.; Drake, J.; Roensch, F.R.; Cappis, J.H.; Perrin, R.E.

1986-05-01T23:59:59.000Z

222

Mass spectrometry of nuclear materials; Attention to detail  

SciTech Connect

Measurements of the {sup 235}U/{sup 238}U ratio in product-quality material have improved from uncertainties of 0.1 percent (rel) to 0.2 percent since the Manhattan Project. The hardware and procedural changes responsible for these measurement improvements are traced and discussed.

Shields, W.R

1989-11-01T23:59:59.000Z

223

Applications of Ionic Clusters in High Resolution Mass Spectrometry  

E-Print Network (OSTI)

of the ions by blackbody radiation or collisions withcathode heated due to blackbody radiation from the cell andby absorption of blackbody radiation, the precursor ions

Leib, Ryan David

2010-01-01T23:59:59.000Z

224

Spatially resolved thermal desorption/ionization coupled with mass spectrometry  

DOE Patents (OSTI)

A system and method for sub-micron analysis of a chemical composition of a specimen are described. The method includes providing a specimen for evaluation and a thermal desorption probe, thermally desorbing an analyte from a target site of said specimen using the thermally active tip to form a gaseous analyte, ionizing the gaseous analyte to form an ionized analyte, and analyzing a chemical composition of the ionized analyte. The thermally desorbing step can include heating said thermally active tip to above 200.degree. C., and positioning the target site and the thermally active tip such that the heating step forms the gaseous analyte. The thermal desorption probe can include a thermally active tip extending from a cantilever body and an apex of the thermally active tip can have a radius of 250 nm or less.

Jesse, Stephen; Van Berkel, Gary J; Ovchinnikova, Olga S

2013-02-26T23:59:59.000Z

225

Secondary Ion Mass Spectrometry of Vapor-Liquid-Solid Grown,  

E-Print Network (OSTI)

photovoltaic cells,1-5 field-effect transistors,6,7 light-emitting diodes,8 photodetectors,9 and molecular sen

Heaton, Thomas H.

226

Advances in computational mass spectrometry : phosphoprotoemics and proteogenomics  

E-Print Network (OSTI)

and phosphorylation mediated NF-KB activiation. Four histoneto be activated, or relay the signal. In NF-KB signaling, atranscription factor (NF-KB) is held inactive outside the

Payne, Samuel Harris

2008-01-01T23:59:59.000Z

227

Hadamard Transform Time-of-Flight Mass Spectrometry  

E-Print Network (OSTI)

of the ions. This multiplexing scheme in- creases the ion usage to 50% for a single detector instrument consists of a combination of magnetic and electric resolving stages. This is probably the oldest type

Zare, Richard N.

228

2-4 High-Performance Mass Spectrometry Facility  

NLE Websites -- All DOE Office Websites (Extended Search)

through soil and into groundwater. The mechanism for this reduction in contaminant mobility is the transfer of an electron to the heavy metal through cell surface proteins...

229

Proposal of physics with exotic beams at Oak Ridge  

SciTech Connect

A facility to produce proton-rich radioactive beams for nuclear structure and astrophysics experiments is proposed. This Oak Ridge Exotic Beam (OREB) facility is based on two existing accelerators. Beams of mass up to 80 can be accelerated to energies of about 5 MeV/nucleon. It will provide opportunities to study new areas in nuclear physics and astrophysics that are not available with the use of stable beams. 3 figs.

Lee, I-Yang.

1991-01-01T23:59:59.000Z

230

Stable Isotope, Site-Specific Mass Tagging For Protein Identification  

NLE Websites -- All DOE Office Websites (Extended Search)

Stable Isotope, Site-Specific Mass Tagging For Protein Stable Isotope, Site-Specific Mass Tagging For Protein Identification Stable Isotope, Site-Specific Mass Tagging For Protein Identification Proteolytic peptide mass mapping as measured by mass spectrometry provides an important method for the identification of proteins, which are usually identified by matching the measured and calculated m/z values of the proteolytic peptides. Available for thumbnail of Feynman Center (505) 665-9090 Email Stable Isotope, Site-Specific Mass Tagging For Protein Identification Proteolytic peptide mass mapping as measured by mass spectrometry provides an important method for the identification of proteins, which are usually identified by matching the measured and calculated m/z values of the proteolytic peptides. A unique identification is, however, heavily

231

Simple beam profile monitor  

Science Conference Proceedings (OSTI)

An inexpensive beam profile monitor is based on the well proven rotating wire method. The monitor can display beam position and shape in real time for particle beams of most energies and beam currents up to 200{mu}A. Beam shape, position cross-section and other parameters are displayed on a computer screen.

Gelbart, W.; Johnson, R. R.; Abeysekera, B. [ASD Inc. Garden Bay, BC (Canada); Best Theratronics Ltd Ottawa Ontario (Canada); PharmaSpect Ltd., Burnaby BC (Canada)

2012-12-19T23:59:59.000Z

232

Design and development of an ultrafine particle reflection-time-of-flight mass spectrometer  

E-Print Network (OSTI)

The primary motivation for the research is to study the effect of small particles on global climate. The study can also help to understand the dynamics involved with gas to particle conversion, which is being debated to be a rich source for atmospheric aerosol. However, the most important use would be to study health effects, since small particles easily diffuse into the lungs, with seemingly little physiological filtration mechanism. The research work involves the design, development and characterization of a single-ultrafine-particle mass spectrometer. The instrument aerodynamically size selects fine and ultrafine aerosol particles (size range 20 nm-1 []m), with a constant Stokes number, and focuses them into a vacuum chamber. This is achieved by changing the upstream pressure of the inlet, which changes aerodynamic drag experienced by the particle. After its entry into the chamber, the particle is ablated by a high power excimer laser, which produces ions from the original molecular constituents. Reflectron time-of-flight mass spectrometry is utilized to analyze the ions, and thus the chemical composition of the particle that was hit. The present work is aimed to overcome the shortcomings of previous instruments, while allowing for increased portability. The instrument is designed, fabricated and experimentally characterized. The first phase involves analysis of the particle beam generated by the inlet. An atomizer generates aerosols from a solution of 5% oleic acid and ethanol. The polydisperse aerosol is passed through a differential mobility analyzer to make a monodisperse mixture, which is transmitted through the inlet. The monodisperse particle beam is intercepted by glass slides, and the spot sizes are indicative of the beam shape and width at the slide positions. A theoretical analysis of the fluid flow field and particle trajectory is developed to correlate with the experimental results. The second phase involves calibration of the mass spectra, and measuring some particulate composition from the laboratory room air.

Das, Rishiraj

2002-01-01T23:59:59.000Z

233

Negative mass  

E-Print Network (OSTI)

Some physical aspects of negative mass are examined. Several unusual properties, such as the ability of negative mass to penetrate any armor, are analyzed. Other surprising effects include the bizarre system of negative mass chasing positive pass, naked singularities and the violation of cosmic censorship, wormholes, and quantum mechanical results as well. In addition, a brief look into the implications for strings is given.

Richard T Hammond

2013-08-06T23:59:59.000Z

234

Relativistic electron beam generator  

DOE Patents (OSTI)

A relativistic electron beam generator for laser media excitation is described. The device employs a diode type relativistic electron beam source having a cathode shape which provides a rectangular output beam with uniform current density.

Mooney, L.J.; Hyatt, H.M.

1975-11-11T23:59:59.000Z

235

NK Muon Beam  

Science Conference Proceedings (OSTI)

The NK Muon Beam will be a modified version of the existing NT beam line. The decision to employ a modified version of the NT beam line was made based on considerations of cost and availability of the beam line. Preliminary studies considered use of other beam lines, e.g., the NW beam line, and even of moving the bubble chamber with its superconducting coils but were rejected for reasons such as cost, personnel limitations, and potential conflicts with other users.

Koizumi, G.

1988-09-28T23:59:59.000Z

236

Comparison of Current Almond Pasteurization Methods and Electron Beam Irradiation as an Alternative  

E-Print Network (OSTI)

Two outbreaks of salmonellosis were linked to the consumption of raw California almonds in 2001 and 2004. Current federal regulations mandate that all almonds grown in California are to be treated with a process that results in a 4-log reduction of Salmonella. Since four out of the five approved technologies to pasteurize almonds rely on the application of heat to control Salmonella, the evaluation of alternative technologies against heat resistant Salmonella Senftenberg was imminent. In this study, almonds that were inoculated with S. Enteritidis PT 30 and S. Senftenberg, were treated with electron beam irradiation (e-beam), blanching and oil roasting. The thermal death time (D-value) for S. Enteritidis PT 30 when treated with e-beam was 0.90 kGy, 15 s when subjected to blanching at 88 degrees C, and 13 s when treated with oil at 127 degrees C. Irradiation and thermal resistance of S. Senftenberg was not significantly different (P > 0.05) from S. Enteritidis PT 30. The commercial application of e-beam as a pathogen intervention was assessed through Monte Carlo simulations (MCS) and experimental measurements. The sensory characteristics of almonds commercially treated by e-beam, blanching and roasting were assessed by a consumer panel. Irradiated and blanched almonds did not differ in consumer overall like (P > 0.05). Bitterness and rancidity attributes of irradiated almonds were between a "dislike slightly" and "dislike moderately", whereas blanched and roasted almonds were between "neither like nor dislike" and "like slightly". Almonds commercially irradiated, blanched and roasted were subjected to an accelerated shelf-life test (ASLT) evaluating percentage free fatty acids, peroxide value, and 2-thiobarbituric acid reactive substances (TBARs). No clear differences between treatments were observed at any given point in time in any of the chemical tests. A gas chromatography-mass-spectrometry-olfactometry (MDGC-MS-O) technology was used to compare full aroma and flavor profiles from raw and e-beam irradiated almonds. Differences in the aroma/odor profile and the taste analysis revealed that the difference between raw and irradiated almonds is extremely subtle. In conclusion, e-beam may be a feasible technology to control Salmonella in almonds if used at low doses, as a part of a series of interventions.

Cuervo Pliego, Mary

2011-12-01T23:59:59.000Z

237

Power beaming: Mission enabling for lunar exploration  

SciTech Connect

This paper explores several beam power concepts proposed for powering either lunar base or rover vehicles. At present, power requirements to support lunar exploration activity are met by integral self-contained power system designs. To provide requisite energy flexibility for human expansion into space, an innovative approach to replace on-board self-contained power systems is needed. Power beaming provides an alternative approach to supplying power that would ensure increased mission flexibility while reducing total mass launched into space. Providing power to the moon presents significant design challenges because of the duration of the lunar night. Power beaming provides an alternative to solar photovoltaic systems coupled with battery storage, radioisotope thermoelectric generation, and surface nuclear power. The Synthesis Group describes power beaming as a technology supporting lunar exploration. In this analysis beam power designs are compared to conventional power generation methods.

Bamberger, J.A.

1992-01-01T23:59:59.000Z

238

Mass Measurements  

Science Conference Proceedings (OSTI)

... NIST maintains the national standard for mass in the form of the prototype kilogram (K20) and provides services to support the parts of the national ...

2013-06-28T23:59:59.000Z

239

fehlende Masse  

NLE Websites -- All DOE Office Websites (Extended Search)

beim radioaktiven Zerfall mit der fehlenden Masse?" Zur Erinnerung: wenn Uran in Thorium und ein alpha Teilchen zerfllt, dann gehen 0.0046 u (Masseneinheiten) der...

240

Beam instrumentation for an ISOL test stand  

SciTech Connect

TRIUMF is constructing a test bed for the first stages of the proposed TISAC accelerated radioactive beam facility. The authors will present the requirements for the diagnostic system for this test stand and describe the design and development work underway. Scintillators, beamstops and a Faraday Cup have been tested using stable, mass analyzed, 12 keV beams of ions from mass 14 to 132. The design of a linear drive, with 10 {micro}m resolution, for scanning wires and slits has begun.

Mackenzie, G.H.; Dombsky, M.; Rawnsley, W.; Stanford, G.; Yin, Y. [TRIUMF, Vancouver, British Columbia (Canada); Novikov, A. [INR, Moscow (Russian Federation)

1995-09-01T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

SUMMARY OF BEAM BEAM OBSERVATIONS DURING STORES IN RHIC.  

Science Conference Proceedings (OSTI)

During stores, the beam-beam interaction has a significant impact on the beam and luminosity lifetimes in RHIC. This was observed in heavy ion, and even more pronounced in proton collisions. Observations include measurements of beam-beam induced tune shifts, lifetime and emittance growth measurements with and without beam-beam interaction, and background rates as a function of tunes. In addition, RHIC is currently the only hadron collider in which strong-strong beam-beam effects can be seen. Coherent beam-beam modes were observed, and suppressed by tune changes. In this article we summarize the most important beam-beam observations made during stores so far.

FISCHER,W.

2003-05-19T23:59:59.000Z

242

Field Asymmetric Ion Mobility Spectrometry (FAIMS ...  

Summary. Field asymmetric Ion mobility spectrometry (FAIMS), wherein ions are separated and/or characterized by differences in their mobility in high ...

243

RAPID COMMUNICATIONS IN MASS SPECTROMETRY Rapid Commun. Mass Spectrom. 2005; 19: 34423450  

E-Print Network (OSTI)

and oxygen isotope ratios of bottled waters of the world Gabriel J. Bowen1 *, David A. Winter2 , Howard J Biology Department, University of Utah, Salt Lake City, UT 84112, USA 2 Department of Geology, University of Calfornia, Davis, CA 95616, USA 3 Geology and Geophysics, University of Utah, Salt Lake City, UT 84112, USA

Ehleringer, Jim

244

Tevatron beam-beam compensation project progress  

SciTech Connect

In this paper, we report the progress of the Tevatron Beam-Beam Compensation (BBC) project [1]. Electron beam induced proton and antiproton tuneshifts have been reported in [2], suppression of an antiproton emittance growth has been observed, too [1]. Currently, the first electron lens (TEL1) is in operational use as the Tevatron DC beam cleaner. We have made a lot of the upgrades to improve its stability [3]. The 2nd Tevatron electron lens (TEL2) is under the final phase of development and preparation for installation in the Tevatron.

Shiltsev, V.; Zhang, X.L.; Kuznetsov, G.; Pfeffer, H.; Saewert, G.; /Fermilab; Zimmermann, F.; /CERN; Tiunov, M.; /Novosibirsk, IYF; Bishofberger, K.; /UCLA; Bogdanov, I.; Kashtanov, E.; Kozub, S.; Sytnik, V.; Tkachenko, L.; /Serpukhov, IHEP

2005-05-01T23:59:59.000Z

245

ION BEAM COLLIMATOR  

DOE Patents (OSTI)

A device is described for defining a beam of high energy particles wherein the means for defining the beam in the horizontal and vertical dimension are separately adjustable and the defining members are internally cooled. In general, the device comprises a mounting block having a central opening through which the beam is projected, means for rotatably supporting two pairs of beam- forming members, passages in each member for the flow of coolant; the beam- forming members being insulated from each other and the block, and each having an end projecting into the opening. The beam-forming members are adjustable and may be cooperatively positioned to define the beam passing between the end of the members. To assist in projecting and defining the beam, the member ends have individual means connected thereto for indicating the amount of charge collected thereon due to beam interception.

Langsdorf, A.S. Jr.

1957-11-26T23:59:59.000Z

246

Molecular beam kinetics  

SciTech Connect

The design of a crossed molecular beam ''supermachine'' for neutral-- neutral collisions is discussed. The universal electron bombardment ionizer, mass filter, and ion detection system of the detector, the supersonic nozzle sources, the differential pumping arrangement for the sources and detector, the time-of-flight detection of scattered products, and the overall configuration of the apparatus are described. The elastic scattering of two systems, CH$sub 4$ + Ar and NH$sub 3$ + Ar, has been measured using the supermachine with two supersonic nozzle sources. The rainbow structure and the interference oscillations are seen in each system. The best fit to the data was found using a Morse--Spline--Van der Waals (MSV) potential. The three potential parameters epsilon, r/sub m/, and $beta$ were found to be 2.20(+-0.04) x 10$sup -14$ ergs, 3.82(+-0.04)A, and 7.05 +- 0.20 for CH$sub 4$ + Ar, and 2.21(+-0.04) x 10$sup - 14$ ergs 3.93 (+-0.05)A, and 8.45 +- 0.30 for NH$sub 3$ + Ar. A new phenomenon in crossed molecular beams of condensation of a molecule on a cluster to form a complex was observed. A bromine molecule condensed on clusters of chlorine (Cl$sub 2$)/sub chi/ and ammonia (NH$sub 3$)/sub chi/. The value of chi for measurements in these experiments ranges from 7 to 40 for chlorine clusters and from 10 to 70 ammonia clusters. (auth)

Behrens, R. Jr.

1975-11-01T23:59:59.000Z

247

Beam position monitor  

DOE Patents (OSTI)

An apparatus for determining the position of an x-ray beam relative to a desired beam axis where the apparatus is positioned along the beam path so that a thin metal foil target intersects the x-ray beam generating fluorescent radiation. A PIN diode array is positioned so that a portion of the fluorescent radiation is intercepted by the array resulting in a series of electrical signals from the PIN diodes making up the array. The signals are then analyzed and the position of the x-ray beam is determined relative to the desired beam path.

Alkire, Randy W.; Rosenbaum, Gerold; Evans, Gwyndaf

2000-09-21T23:59:59.000Z

248

High brilliance negative ion and neutral beam source  

DOE Patents (OSTI)

A high brilliance mass selected (Z-selected) negative ion and neutral beam source having good energy resolution. The source is based upon laser resonance ionization of atoms or molecules in a small gaseous medium followed by charge exchange through an alkali oven. The source is capable of producing microampere beams of an extremely wide variety of negative ions, and milliampere beams when operated in the pulsed mode.

Compton, R.N.

1990-01-03T23:59:59.000Z

249

Beam injection into RHIC  

SciTech Connect

During the RHIC sextant test in January 1997 beam was injected into a sixth of one of the rings for the first time. The authors describe the injection zone and its bottlenecks. They report on the commissioning of the injection system, on beam based measurements of the kickers and the application program to steer the beam.

Fischer, W.; Hahn, H.; MacKay, W.W.; Satogata, T.; Tsoupas, N.; Zhang, W.

1997-07-01T23:59:59.000Z

250

Electron beam device  

DOE Patents (OSTI)

This patent pertains to an electron beam device in which a hollow target is symmetrically irradiated by a high energy, pulsed electron beam about its periphery and wherein the outer portion of the target has a thickness slightly greater than required to absorb the electron beam pulse energy. (auth)

Beckner, E.H.; Clauser, M.J.

1975-08-12T23:59:59.000Z

251

BEAM CONTROL PROBE  

DOE Patents (OSTI)

A probe is described for intercepting a desired portion of a beam of charged particles and for indicating the spatial disposition of the beam. The disclosed probe assembly includes a pair of pivotally mounted vanes moveable into a single plane with adjacent edges joining and a calibrated mechanical arrangement for pivoting the vancs apart. When the probe is disposed in the path of a charged particle beam, the vanes may be adjusted according to the beam current received in each vane to ascertain the dimension of the beam.

Chesterman, A.W.

1959-03-17T23:59:59.000Z

252

EUROv Super Beam Studies  

Science Conference Proceedings (OSTI)

Neutrino Super Beams use conventional techniques to significantly increase the neutrino beam intensity compared to the present neutrino facilities. An essential part of these facilities is an intense proton driver producing a beam power higher than a MW. The protons hit a target able to accept the high proton beam intensity. The produced charged particles are focused by a system of magnetic horns towards the experiment detectors. The main challenge of these projects is to deal with the high beam intensity for many years. New high power neutrino facilities could be build at CERN profiting from an eventual construction of a high power proton driver. The European FP7 Design Study EUROv, among other neutrino beams, studies this Super Beam possibility. This paper will give the latest developments in this direction.

Dracos, Marcos [IPHC, Universite de Strasbourg, CNRS/IN2P3, F-67037 Strasbourg (France)

2011-10-06T23:59:59.000Z

253

Nuclear Materials Identification System (NMIS) with Gamma Spectrometry for Attributes of Pu, HEU, and Detection of HE and Chemical Agents  

SciTech Connect

A combined Nuclear Materials Identification System (NMIS)-gamma ray spectrometry system can be used passively to obtain the following attributes of Pu: presence, fissile mass, 240/239 ratio, and metal vs. oxide. This system can also be used with a small, portable, DT neutron generator to measure the attributes of highly enriched uranium (HEU): presence, fissile mass, enrichment, metal vs. oxide; and detect the presence of high explosives (HE). For the passive system, time-dependent coincidence distributions can be used for the presence, fissile mass, metal vs. oxide for Pu, and gamma-ray spectrometry can be used for 239/240 ratio and presence. So presence can be confirmed by two methods. For the active system with a DT neutron generator, all four attributes for both Pu and HEU can be determined from various features of the time-dependent coincidence distribution measurements for both Pu and HEU. Active gamma ray spectrometry would also give presence and 240/239 ratio for Pu, enrichment for HEU, and metal vs. oxide for both. Active gamma ray spectrometry would determine the presence of HE. The various features of time-dependent coincidence distributions and gamma ray spectrometry that determine these attributes are discussed with some examples from previous determinations.

Mihalczo, J. T.; Mattingly, J. K.; Mullens, J. A.; Neal, J. S.

2002-05-01T23:59:59.000Z

254

Mass Finishing  

Science Conference Proceedings (OSTI)

Table 8 Operating conditions for mass finishing...Brass screw-machine parts Aluminum oxide or granite 6.4-19 0.25-0.75 [MathExpression] -6 Light matte or bright Light cutting (a) Brass stampings or screws (b) Limestone 3.2-13 0.13-0.50 2-6 Bright (a) Submerged tumbling is used for fragile and precision parts. (b) Screw-machine parts...

255

Strong-strong beam-beam simulation on parallel computer  

DOE Green Energy (OSTI)

The beam-beam interaction puts a strong limit on the luminosity of the high energy storage ring colliders. At the interaction points, the electromagnetic fields generated by one beam focus or defocus the opposite beam. This can cause beam blowup and a reduction of luminosity. An accurate simulation of the beam-beam interaction is needed to help optimize the luminosity in high energy colliders.

Qiang, Ji

2004-08-02T23:59:59.000Z

256

Chemical ionization tandem mass spectrometer for the in situ measurement of methyl hydrogen peroxide  

SciTech Connect

A new approach for measuring gas-phase methyl hydrogen peroxide [(MHP) CH{sub 3}OOH] utilizing chemical ionization mass spectrometry is presented. Tandem mass spectrometry is used to avoid mass interferences that hindered previous attempts to measure atmospheric CH{sub 3}OOH with CF{sub 3}O{sup -} clustering chemistry. CH{sub 3}OOH has been successfully measured in situ using this technique during both airborne and ground-based campaigns. The accuracy and precision for the MHP measurement are a function of water vapor mixing ratio. Typical precision at 500 pptv MHP and 100 ppmv H{sub 2}O is {+-}80 pptv (2 sigma) for a 1 s integration period. The accuracy at 100 ppmv H{sub 2}O is estimated to be better than {+-}40%. Chemical ionization tandem mass spectrometry shows considerable promise for the determination of in situ atmospheric trace gas mixing ratios where isobaric compounds or mass interferences impede accurate measurements.

St Clair, Jason M.; McCabe, David C. [Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, California 91125 (United States); Crounse, John D. [Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125 (United States); Steiner, Urs [Varian, Inc., Santa Clara, California 95051 (United States); Wennberg, Paul O. [Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, California 91125 (United States); Division of Engineering and Applied Science, California Institute of Technology, Pasadena, California 91125 (United States)

2010-09-15T23:59:59.000Z

257

Beam-Gas  

NLE Websites -- All DOE Office Websites (Extended Search)

Gas Gas and Thermal Photon Scattering in the NLC Main Linac as a Source of Beam Halo P. Tenenbaum LCC-Note-0051 12-JAN-2001 Abstract Scattering of primary beam electrons off of residual gas molecules or blackbody radiation photons in the NLC main linac has been identified as a potential source of beam haloes which must be collimated in the beam delivery system. We consider the contributions from four scat- tering mechanisms: inelastic thermal-photon scattering, elastic beam-gas (Coulomb) scattering inelastic beam-gas (Bremsstrahlung) scattering, and atomic-electron scattering. In each case we develop the formalism necessary to estimate the backgrounds generated in the main linac, and determine the expected number of off-energy or large-amplitude particles from each process, assuming a main linac injection energy of 8 GeV and extraction energy of 500 GeV. 1 Introduction The

258

Ion Beam Materials Lab  

NLE Websites -- All DOE Office Websites (Extended Search)

Facilities » Facilities » Ion Beam Materials Lab Ion Beam Materials Lab A new research frontier awaits! Our door is open and we thrive on mutually beneficial partnerships, collaborations that drive innovations and new technologies. April 12, 2012 Ion Beam Danfysik Implanter High Voltage Terminal. Contact Yongqiang Wang (505) 665-1596 Email Devoted to the characterization and modification of surfaces through the use of ion beams The Ion Beam Materials Laboratory (IBML) is a Los Alamos National Laboratory resource devoted to the characterization and modification of surfaces through the use of ion beams. The IBML provides and operates the core facilities, while supporting the design and implementation of specific apparati needed for experiments requested by users of the facility. The result is a facility with

259

Particle beam injection system  

SciTech Connect

This invention provides a poloidal divertor for stacking counterstreaming ion beams to provide high intensity colliding beams. To this end, method and apparatus are provided that inject high energy, high velocity, ordered, atomic deuterium and tritium beams into a lower energy, toroidal, thermal equilibrium, neutral, target plasma column that is magnetically confined along an endless magnetic axis in a strong restoring force magnetic field having helical field lines to produce counterstreaming deuteron and triton beams that are received bent, stacked and transported along the endless axis, while a poloidal divertor removes thermal ions and electrons all along the axis to increase the density of the counterstreaming ion beams and the reaction products resulting therefrom. By balancing the stacking and removal, colliding, strong focused particle beams, reaction products and reactions are produced that convert one form of energy into another form of energy.

Jassby, Daniel L. (Princeton, NJ); Kulsrud, Russell M. (Princeton, NJ)

1977-01-01T23:59:59.000Z

260

Piezoelectric energy harvester having planform-tapered interdigitated beams  

Science Conference Proceedings (OSTI)

Embodiments of energy harvesters have a plurality of piezoelectric planform-tapered, interdigitated cantilevered beams anchored to a common frame. The plurality of beams can be arranged as two or more sets of beams with each set sharing a common sense mass affixed to their free ends. Each set thus defined being capable of motion independent of any other set of beams. Each beam can comprise a unimorph or bimorph piezoelectric configuration bonded to a conductive or non-conductive supporting layer and provided with electrical contacts to the active piezoelectric elements for collecting strain induced charge (i.e. energy). The beams are planform tapered along the entirety or a portion of their length thereby increasing the effective stress level and power output of each piezoelectric element, and are interdigitated by sets to increase the power output per unit volume of a harvester thus produced.

Kellogg, Rick A. (Tijeras, NM); Sumali, Hartono (Albuquerque, NM)

2011-05-24T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

BEAMS Crossword Puzzle  

NLE Websites -- All DOE Office Websites (Extended Search)

puzzle with words from the BEAMS Vocabulary List. Download this Activity Lab Pages Puzzle Puzzle Puzzle (cont) Puzzle (cont) Sample AnswersAnswer Key Ansewr Key Ansewr Key...

262

Electron Beam Melting (EBM)  

Science Conference Proceedings (OSTI)

Oct 18, 2011 ... Additive Manufacturing of Metals: Electron Beam Melting (EBM) I Sponsored by: MS&T Organization Program Organizers: Ian D. Harris, EWI; ...

263

Electron Beam Melting  

Science Conference Proceedings (OSTI)

Oct 9, 2012 ... Additive Manufacturing of Metals: Electron Beam Melting Program Organizers: Ian Harris, EWI; Ola Harrysson, North Carolina State University; ...

264

Broad beam ion implanter  

DOE Patents (OSTI)

An ion implantation device for creating a large diameter, homogeneous, ion beam is described, as well as a method for creating same, wherein the device is characterized by extraction of a diverging ion beam and its conversion by ion beam optics to an essentially parallel ion beam. The device comprises a plasma or ion source, an anode and exit aperture, an extraction electrode, a divergence-limiting electrode and an acceleration electrode, as well as the means for connecting a voltage supply to the electrodes.

Leung, Ka-Ngo (Hercules, CA)

1996-01-01T23:59:59.000Z

265

Method and apparatus for measuring the momentum, energy, power, and power density profile of intense particle beams  

DOE Patents (OSTI)

A method and apparatus for determining the power, momentum, energy, and power density profile of high momentum mass flow. Small probe projectiles of appropriate size, shape and composition are propelled through an intense particle beam at equal intervals along an axis perpendicular to the beam direction. Probe projectiles are deflected by collisions with beam particles. The net beam-induced deflection of each projectile is measured after it passes through the intense particle beam into an array of suitable detectors.

Gammel, George M. (Merrick, NY); Kugel, Henry W. (Somerset, NJ)

1992-10-06T23:59:59.000Z

266

Method and apparatus for measuring the momentum, energy, power, and power density profile of intense particle beams  

DOE Patents (OSTI)

A method and apparatus for determining the power, momentum, energy, and power density profile for high momentum mass flow. Small probe projectiles of appropriate size, shape and composition are propelled through an intense particle beam at equal intervals along an axis perpendicular to the beam direction. Probe projectiles are deflected by collisions with beam particles. The net beam-induced deflection of each projectile is measured after it passes through the intense particle beam into an array of suitable detectors.

Gammel, G.M.; Kugel, H.W.

1991-12-31T23:59:59.000Z

267

On the Aerosol Particle Size Distribution Spectrum in Alaskan Air Mass Systems: Arctic Haze and Non-Haze Episodes  

Science Conference Proceedings (OSTI)

Aerosols in central Alaskan winter air mass system were classified according to size by diffusive separation and light-scattering spectrometry. Particles entering central Alaska from the Pacific Marine environment had number concentrations ...

Glenn E. Shaw

1983-05-01T23:59:59.000Z

268

Chemical Ionization Mass Spectrometer (CIMS) Shanhu Lee, Kent State University (http://www.personal.kent.edu/~slee19/)  

E-Print Network (OSTI)

Chemical Ionization Mass Spectrometer (CIMS) Shanhu Lee, Kent State University (http ionization mass spectrometry (PTR-CIMS). A typical CIMS instrument can be constructed from an ion source, an ion molecular reactor, and a quadrupole mass spectrometer. Shown below is schematic diagram of a CIMS

Lee, Shan-Hu

269

Laser beam generating apparatus  

DOE Patents (OSTI)

Laser beam generating apparatus including a septum segment disposed longitudinally within the tubular structure of the apparatus. The septum provides for radiatively dissipating heat buildup within the tubular structure and for generating relatively uniform laser beam pulses so as to minimize or eliminate radial pulse delays (the chevron effect). 11 figures.

Warner, B.E.; Duncan, D.B.

1993-12-28T23:59:59.000Z

270

Laser beam generating apparatus  

DOE Patents (OSTI)

Laser beam generating apparatus including a septum segment disposed longitudinally within the tubular structure of the apparatus. The septum provides for radiatively dissipating heat buildup within the tubular structure and for generating relatively uniform laser beam pulses so as to minimize or eliminate radial pulse delays (the chevron effect).

Warner, Bruce E. (Livermore, CA); Duncan, David B. (Auburn, CA)

1994-01-01T23:59:59.000Z

271

Laser beam generating apparatus  

DOE Patents (OSTI)

Laser beam generating apparatus including a septum segment disposed longitudinally within the tubular structure of the apparatus is described. The septum provides for radiatively dissipating heat buildup within the tubular structure and for generating relatively uniform laser beam pulses so as to minimize or eliminate radial pulse delays (the chevron effect). 7 figures.

Warner, B.E.; Duncan, D.B.

1994-02-15T23:59:59.000Z

272

Laser beam generating apparatus  

DOE Patents (OSTI)

Laser beam generating apparatus including a septum segment disposed longitudinally within the tubular structure of the apparatus. The septum provides for radiatively dissipating heat buildup within the tubular structure and for generating relatively uniform laser beam pulses so as to minimize or eliminate radial pulse delays (the chevron effect).

Warner, Bruce E. (Livermore, CA); Duncan, David B. (Auburn, CA)

1993-01-01T23:59:59.000Z

273

Beam Diagnostics for FACET  

SciTech Connect

FACET, the Facility for Advanced Accelerator and Experimental Tests, is a new facility being constructed in sector 20 of the SLAC linac primarily to study beam driven plasma wakefield acceleration beginning in summer 2011. The nominal FACET parameters are 23GeV, 3nC electron bunches compressed to about 20 {micro}m long and focussed to about 10 {micro}m wide. Characterization of the beam-plasma interaction requires complete knowledge of the incoming beam parameters on a pulse-to-pulse basis. FACET diagnostics include Beam Position Monitors, Toroidal current monitors, X-ray and Cerenkov based energy spectrometers, optical transition radiation (OTR) profile monitors and coherent transition radiation (CTR) bunch length measurement systems. The compliment of beam diagnostics and their expected performance are reviewed. Beam diagnostic measurements not only provide valuable insights to the running and tuning of the accelerator but also are crucial for the PWFA experiments in particular. Beam diagnostic devices are being set up at FACET and will be ready for beam commissioning in summer 2011.

Li, S.Z.; Hogan, M.J.; /SLAC

2011-08-19T23:59:59.000Z

274

Laser beam alignment system  

DOE Patents (OSTI)

A plurality of pivotal reflectors direct a high-power laser beam onto a workpiece, and a rotatable reflector is movable to a position wherein it intercepts the beam and deflects a major portion thereof away from its normal path, the remainder of the beam passing to the pivotal reflectors through an aperture in the rotating reflector. A plurality of targets are movable to positions intercepting the path of light traveling to the pivotal reflectors, and a preliminary adjustment of the latter is made by use of a low-power laser beam reflected from the rotating reflector, after which the same targets are used to make a final adjustment of the pivotal reflectors with the portion of the high-power laser beam passed through the rotating reflector.

Kasner, William H. (11686 Althea Dr., Pittsburgh, PA 15235); Racki, Daniel J. (712 Union Cemetery Rd., Greensburg, PA 15601); Swenson, Clark E. (228 Scott Dr., Monroeville, PA 15146)

1984-01-01T23:59:59.000Z

275

Beam director design report  

Science Conference Proceedings (OSTI)

A design and fabrication effort for a beam director is documented. The conceptual design provides for the beam to pass first through a bending and focusing system (or ''achromat''), through a second achromat, through an air-to-vacuum interface (the ''beam window''), and finally through the vernier steering system. Following an initial concept study for a beam director, a prototype permanent magnet 30/sup 0/ beam-bending achromat and prototype vernier steering magnet were designed and built. In volume II, copies are included of the funding instruments, requests for quotations, purchase orders, a complete set of as-built drawings, magnetic measurement reports, the concept design report, and the final report on the design and fabrication project. (LEW)

Younger, F.C.

1986-08-01T23:59:59.000Z

276

First Beam to FACET  

Science Conference Proceedings (OSTI)

The SLAC 3km linear electron accelerator has been reconfigured to provide a beam of electrons to the new Facility for Advanced Accelerator Experimental Tests (FACET) while simultaneously providing an electron beam to the Linac Coherent Light Source (LCLS). On June 23, 2011, the first electron beam was transported through this new facility. Commissioning of FACET is in progress. On June 23, 2011, an electron beam was successfully transported through the new FACET system to a dump in Sector 20 in the linac tunnel. This was achieved while the last third of the linac, operating from the same control room, but with a separate injector system, was providing an electron beam to the Linac Coherent Light Source (LCLS), demonstrating that concurrent operation of the two facilities is practical. With the initial checkout of the new transport line essentially complete, attention is now turning toward compressing the electron bunches longitudinally and focusing them transversely to support a variety of accelerator science experiments.

Erickson, R.; Clarke, C.; Colocho, W.; Decker, F.-J.; Hogan, M.; Kalsi, S.; Lipkowitz, N.; Nelson, J.; Phinney, N.; Schuh, P.; Sheppard, J.; Smith, H.; Smith, T.; Stanek, M.; Turner, J.; Warren, J.; Weathersby, S.; Wienands, U.; Wittmer, W.; Woodley, M.; Yocky, G.; /SLAC

2011-12-13T23:59:59.000Z

277

Reactive Collisions in Crossed Molecular Beams  

DOE R&D Accomplishments (OSTI)

The distribution of velocity vectors of reaction products is discussed with emphasis on the restrictions imposed by the conservation laws. The recoil velocity that carries the products away from the center of mass shows how the energy of reaction is divided between internal excitation and translation. Similarly, the angular distributions, as viewed from the center of mass, reflect the partitioning of the total angular momentum between angular momenta of individual molecules and orbital angular momentum associated with their relative motion. Crossed-beam studies of several reactions of the type M + RI yields R + MI are described, where M = K, Rb, Cs, and R = CH{sub 3}, C{sub 3}H{sub 5}, etc. The results show that most of the energy of reaction goes into internal excitation of the products and that the angular distribution is quite anisotropic, with most of the MI recoiling backward (and R forward) with respect to the incoming K beam. (auth)

Herschbach, D. R.

1962-02-00T23:59:59.000Z

278

SPEAR3 Beam Line Availability  

NLE Websites -- All DOE Office Websites (Extended Search)

Beam Line Support | Floor Support | Administrative Support SPEAR3 Beam Line Availability Beam Line BL Type Technique(s) Status 1-4 X-ray Small and Wide Angle X-ray Scattering Open...

279

Electron and laser beam welding  

SciTech Connect

This book contains 22 selections. Some of the titles are: Laser welding of chandelles to the plates of the sommier employed in the nuclear power plant core; Electron beam welding of hobbing cutters; Sealing welds in electron beam welding of thick metals; Development and application of high power electron beam welding; Electron beam welding of dissimilar metals (niobium, molybdenum, porous tungsten-molybdenum); Status of electron beam welding in the United States of America; and Electron and laser beam welding in Japan.

1986-01-01T23:59:59.000Z

280

Challenges in Accelerator Beam Instrumentation  

E-Print Network (OSTI)

The challenges in beam instrumentation and diagnostics for present and future particle accelerator projects are presented. A few examples for advanced hadron and lepton beam diagnostics are given.

Wendt, M

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Challenges in Accelerator Beam Instrumentation  

Science Conference Proceedings (OSTI)

The challenges in beam instrumentation and diagnostics for present and future particle accelerator projects are presented. A few examples for advanced hadron and lepton beam diagnostics are given.

Wendt, M.

2009-12-01T23:59:59.000Z

282

Frontiers of Particle Beam Physics  

E-Print Network (OSTI)

Low Emittance e--e+ Beams, Brookhaven National Laboratory,Island, NY, October 1988, Brookhaven National Laboratory,Low Emittance e--e+ Beams, Brookhaven National Laboratory,

Sessler, Andrew M.

2008-01-01T23:59:59.000Z

283

Simulations of beam-beam and beam-wire interactions in RHIC  

SciTech Connect

The beam-beam interaction is one of the dominant sources of emittance growth and luminosity lifetime deterioration. A current carrying wire has been proposed to compensate long-range beam-beam effects in the LHC and strong localized long-range beam-beam effects are experimentally investigated in the RHIC collider. Tune shift, beam transfer function, and beam loss rate are measured in dedicated experiments. In this paper, they report on simulations to study the effect of beam-wire interactions based on diffusive apertures, beam loss rates, and beam transfer function using a parallelized weak-strong beam simulation code (BBSIMC). The simulation results are compared with measurements performed in RHIC during 2007 and 2008.

Kim, Hyung J.; Sen, Tanaji; /Fermilab; Abreu, Natalia P.; Fischer, Wolfram; /Brookhaven

2009-02-01T23:59:59.000Z

284

BEAM RELATED SYSTEMATICS IN HIGGS BOSON MASS MEASUREMENT  

E-Print Network (OSTI)

It didn't find the Higgs boson as we all but predicted it would, but the aging atom smasher at Fermi

285

Mass and Lifetime Measurements in Storage Rings  

Science Conference Proceedings (OSTI)

Masses of nuclides covering a large area of the chart of nuclides can be measured in storage rings where many ions circulate at the same time. In this paper the recent progress in the analysis of Schottky mass spectrometry data is presented as well as the technical improvements leading to higher accuracy for isochronous mass measurements with a time-of-flight detector. The high sensitivity of the Schottky method down to single ions allows to measure lifetimes of nuclides by observing mother and daughter nucleus simultaneously. In this way we investigated the decay of bare and H-like 140Pr. As we could show the lifetime can be even shortened compared to those of atomic nuclei despite of a lower number of electrons available for internal conversion or electron capture.All these techniques will be implemented with further improvements at the storage rings of the new FAIR facility at GSI in the future.

Weick, H.; Beckert, K.; Beller, P.; Bosch, F.; Dimopoulou, C.; Kozhuharov, C.; Kurcewicz, J.; Mazzocco, M.; Nociforo, C.; Nolden, F.; Steck, M.; Sun, B.; Winkler, M. [Gesellschaft fuer Schwerionenforschung mbH, 64291 Darmstadt (Germany); Brandau, C.; Chen, L.; Geissel, H.; Knoebel, R.; Litvinov, S. A.; Litvinov, Yu. A.; Scheidenberger, C. [Gesellschaft fuer Schwerionenforschung mbH, 64291 Darmstadt (Germany); II. Phys. Institut, Justus-Liebig-Universitaet Giessen, 35392 Giessen (Germany)] (and others)

2007-05-22T23:59:59.000Z

286

Simulation study of beam-beam effects in ion beams with large space charge tuneshift  

Science Conference Proceedings (OSTI)

During low-energy operations with gold-gold collisions at 3.85 GeV beam energy, significant beam lifetime reductions have been observed due to the beam-beam interaction in the presence of large space charge tuneshifts. These beam-beam tuneshift parameters were about an order of magnitude smaller than during regular high energy operations. To get a better understanding of this effect, simulations have been performed. Recent results are presented.

Montag C.

2012-05-20T23:59:59.000Z

287

Seven Channel Multi-collector Isotope Ratio Mass Spectrometer  

Science Conference Proceedings (OSTI)

A new magnetic sector mass spectrometer that utilizes seven full-sized discrete dynode electron multipliers operating simultaneously has been designed, constructed and is in preliminary testing. The instrument utilizes a newly developed ion dispersion lens that enables the mass dispersed individual isotope beams to be separated sufficiently (35 mm) to allow a full-sized discrete dynode pulse counting multiplier to be used for each beam. The ion dispersion lens is a two element electrostatic 90 degree sector device that causes the beam-to-beam dispersion to increase faster than the intra-beam dispersion. Each multiplier is contained in an isolated case with a deflector/condenser lens at the entrance. A 9-sample filament cartridge is mounted on a micro-manipulator two-axis stage that enables adjustment of the filament position with 10 micron resolution within the ion lens. Results of initial testing with actinides will be presented.

Anthony D. Appelhans

2008-07-01T23:59:59.000Z

288

Neutral particle beam intensity controller  

DOE Patents (OSTI)

The neutral beam intensity controller is based on selected magnetic defocusing of the ion beam prior to neutralization. The defocused portion of the beam is dumped onto a beam dump disposed perpendicular to the beam axis. Selective defocusing is accomplished by means of a magnetic field generator disposed about the neutralizer so that the field is transverse to the beam axis. The magnetic field intensity is varied to provide the selected partial beam defocusing of the ions prior to neutralization. The desired focused neutral beam portion passes along the beam path through a defining aperture in the beam dump, thereby controlling the desired fraction of neutral particles transmitted to a utilization device without altering the kinetic energy level of the desired neutral particle fraction. By proper selection of the magnetic field intensity, virtually zero through 100% intensity control of the neutral beam is achieved.

Dagenhart, W.K.

1984-05-29T23:59:59.000Z

289

Courses on Beam Physics  

NLE Websites -- All DOE Office Websites (Extended Search)

Beam Physics Beam Physics The following is an incomplete listing of course available for beam physics. United States Particle Accelerator School The US Particle Accelerator School provides educational programs in the field of beams and their associated accelerator technologies not otherwise available to the community of science and technology. Joint Universities Accelerator School Each year JUAS provides a foundation course on accelerator physics and associated technologies. The US-CERN-Japan-Russia Joint Accelerator School The purpose of the US-CERN-Japan-Russia joint school is to better our relations by working together on an advanced topical course every two years, alternating between the U.S., western Europe, Japan and Russia. The last set of courses focused on the frontiers of accelerator technology in

290

BNL | ATF Beam Schedule  

NLE Websites -- All DOE Office Websites (Extended Search)

Beam Schedule (pdf) Beam Schedule (pdf) Sunday Monday Tuesday Wednesday Thursday Friday Saturday 22 1/2 Holiday Holiday 28 January Holiday 4 5 Maintenance 11 12 Maintenance 18 19 Holiday AE52 - DWFA (Euclid), BL2 25 February AE52 - DWFA (Euclid), BL2 1 2 AE50 - PWFA in QNR (UCLA), BL2 8 9 AE50 - PWFA in QNR (UCLA), BL2 15 16 Holiday AE50 - PWFA in QNR (UCLA), BL2 22 March 1 2 AE53 - Nonlinear Compton (UCLA) 8 9 AE53 - Nonlinear Compton (UCLA) 15 16 AE53 - Nonlinear Compton (UCLA) 22 23 29 Sunday Monday Tuesday Wednesday Thursday Friday Saturday User operations (E-beam in use) Ions - Ion generation User operations (laser in use) PWFA - Plasma Wakefield Acceleration User operations (E-beam and laser in use)

291

1996 Beam Instrumentation Workshop  

NLE Websites -- All DOE Office Websites (Extended Search)

1996 Beam Instrumentation Workshop BIW '96 logo The Advanced Photon Source (APS) Argonne National Laboratory May 6-9, 1996 Dear Colleague: It is my pleasure to invite you to the...

292

Intense ion beam generator  

DOE Patents (OSTI)

Methods and apparatus for producing intense megavolt ion beams are disclosed. In one embodiment, a reflex triode-type pulsed ion accelerator is described which produces ion pulses of more than 5 kiloamperes current with a peak energy of 3 MeV. In other embodiments, the device is constructed so as to focus the beam of ions for high concentration and ease of extraction, and magnetic insulation is provided to increase the efficiency of operation.

Humphries, Jr., Stanley (Ithaca, NY); Sudan, Ravindra N. (Ithaca, NY)

1977-08-30T23:59:59.000Z

293

Beam/seam alignment control for electron beam welding  

DOE Patents (OSTI)

This invention relates to a dynamic beam/seam alignment control system for electron beam welds utilizing video apparatus. The system includes automatic control of workpiece illumination, near infrared illumination of the workpiece to limit the range of illumination and camera sensitivity adjustment, curve fitting of seam position data to obtain an accurate measure of beam/seam alignment, and automatic beam detection and calculation of the threshold beam level from the peak beam level of the preceding video line to locate the beam or seam edges.

Burkhardt, Jr., James H. (Knoxville, TN); Henry, J. James (Oak Ridge, TN); Davenport, Clyde M. (Knoxville, TN)

1980-01-01T23:59:59.000Z

294

Small Spot, Brighter Beam  

NLE Websites -- All DOE Office Websites (Extended Search)

Small Spot, Brighter Beam Small Spot, Brighter Beam Small Spot, Brighter Beam Print Do you notice the brighter beam? During the most recent shutdown, all of the corrector magnets were replaced with sextupoles, reducing the horizontal emittance and increasing beam brightness. "This is part of ongoing improvement to keep the ALS on the cutting edge," says Alastair MacDowell, a beamline scientist on Beamline 12.2.2. The brightness has increased by a factor of about three in the storage ring. Beamlines on superbend or center-bend magnets will see the most noticeable increase in brightness, but the horizontal beam size and divergence have been substantially reduced at all beamlines. "We are starting to approach the resolution of many beamlines. Therefore, not every beamline will be able to resolve the full improvement," says Christoph Steier, project leader of the brightness upgrade. Though superbend and center-bend magnet source sizes are reduced by roughly a factor of three, "measured improvements so far range from a factor of 2-2.5," Steier says. He and MacDowell agree that the beamline optics are likely the limiting factor in resolving the full improvement at the beamlines.

295

Overtone Mobility Spectrometry: Part 1. Experimental Observations  

E-Print Network (OSTI)

introduce a new approach for isolating ions having specific mobilities (or collision cross sections). IonsARTICLES Overtone Mobility Spectrometry: Part 1. Experimental Observations Ruwan T. Kurulugama, Indiana University, Bloomington, Indiana, USA A new method that allows a linear drift tube to be operated

Clemmer, David E.

296

Wire Scanner Beam Profile Measurements: LANSCE Facility Beam Development  

SciTech Connect

The Los Alamos Neutron Science Center (LANSCE) is replacing Wire Scanner (WS) beam profile measurement systems. Three beam development tests have taken place to test the new wire scanners under beam conditions. These beam development tests have integrated the WS actuator, cable plant, electronics processors and associated software and have used H{sup -} beams of different beam energy and current conditions. In addition, the WS measurement-system beam tests verified actuator control systems for minimum profile bin repeatability and speed, checked for actuator backlash and positional stability, tested the replacement of simple broadband potentiometers with narrow band resolvers, and tested resolver use with National Instruments Compact Reconfigurable Input and Output (cRIO) Virtual Instrumentation. These beam tests also have verified how trans-impedance amplifiers react with various types of beam line background noise and how noise currents were not generated. This paper will describe these beam development tests and show some resulting data.

Gilpatrick, John D. [Los Alamos National Laboratory; Batygin, Yuri K. [Los Alamos National Laboratory; Gonzales, Fermin [Los Alamos National Laboratory; Gruchalla, Michael E. [Los Alamos National Laboratory; Kutac, Vincent G. [Los Alamos National Laboratory; Martinez, Derwin [Los Alamos National Laboratory; Sedillo, James Daniel [Los Alamos National Laboratory; Pillai, Chandra [Los Alamos National Laboratory; Rodriguez Esparza, Sergio [Los Alamos National Laboratory; Smith, Brian G. [Los Alamos National Laboratory

2012-05-15T23:59:59.000Z

297

High mass resolution time of flight mass spectrometer for measuring products in heterogeneous catalysis in highly sensitive microreactors  

Science Conference Proceedings (OSTI)

We demonstrate a combined microreactor and time of flight system for testing and characterization of heterogeneous catalysts with high resolution mass spectrometry and high sensitivity. Catalyst testing is performed in silicon-based microreactors which have high sensitivity and fast thermal response. Gas analysis is performed with a time of flight mass spectrometer with a modified nude Bayard-Alpert ionization gauge as gas ionization source. The mass resolution of the time of flight mass spectrometer using the ion gauge as ionization source is estimated to m/{Delta}m > 2500. The system design is superior to conventional batch and flow reactors with accompanying product detection by quadrupole mass spectrometry or gas chromatography not only due to the high sensitivity, fast temperature response, high mass resolution, and fast acquisition time of mass spectra but it also allows wide mass range (0-5000 amu in the current configuration). As a demonstration of the system performance we present data from ammonia oxidation on a Pt thin film showing resolved spectra of OH and NH{sub 3}.

Andersen, T.; Jensen, R.; Christensen, M. K.; Chorkendorff, I. [Department of Physics, Danish National Research Foundation's Center for Individual Nanoparticle Functionality (CINF), Technical University of Denmark, Building 312, DK-2800 Kgs. Lyngby (Denmark); Pedersen, T.; Hansen, O. [Department of Micro- and Nanotechnology, Technical University of Denmark, DTU Nanotech Building 345 East, DK-2800 Kgs. Lyngby (Denmark)

2012-07-15T23:59:59.000Z

298

Electron Beam Powder Bed Processes  

Science Conference Proceedings (OSTI)

Advanced Materials, Processes and Applications for Additive Manufacturing : Electron Beam Powder Bed Processes Program Organizers: Andrzej ...

299

Single element laser beam shaper  

DOE Patents (OSTI)

A single lens laser beam shaper for converting laser beams from any spatial profile to a flat-top or uniform spatial profile. The laser beam shaper includes a lens having two aspheric surfaces. The beam shaper significantly simplifies the overall structure in comparison with conventional 2-element systems and therefore provides great ease in alignment and reduction of cost.

Zhang, Shukui (Yorktown, VA); Michelle D. Shinn (Newport News, VA)

2005-09-13T23:59:59.000Z

300

Compact mass spectrometer for plasma discharge ion analysis  

DOE Patents (OSTI)

A mass spectrometer and methods are disclosed for mass spectrometry which are useful in characterizing a plasma. This mass spectrometer for determining type and quantity of ions present in a plasma is simple, compact, and inexpensive. It accomplishes mass analysis in a single step, rather than the usual two-step process comprised of ion extraction followed by mass filtering. Ions are captured by a measuring element placed in a plasma and accelerated by a known applied voltage. Captured ions are bent into near-circular orbits by a magnetic field such that they strike a collector, producing an electric current. Ion orbits vary with applied voltage and proton mass ratio of the ions, so that ion species may be identified. Current flow provides an indication of quantity of ions striking the collector. 7 figs.

Tuszewski, M.G.

1997-07-22T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Compact mass spectrometer for plasma discharge ion analysis  

DOE Patents (OSTI)

A mass spectrometer and methods for mass spectrometry which are useful in characterizing a plasma. This mass spectrometer for determining type and quantity of ions present in a plasma is simple, compact, and inexpensive. It accomplishes mass analysis in a single step, rather than the usual two-step process comprised of ion extraction followed by mass filtering. Ions are captured by a measuring element placed in a plasma and accelerated by a known applied voltage. Captured ions are bent into near-circular orbits by a magnetic field such that they strike a collector, producing an electric current. Ion orbits vary with applied voltage and proton mass ratio of the ions, so that ion species may be identified. Current flow provides an indication of quantity of ions striking the collector.

Tuszewski, Michel G. (Los Alamos, NM)

1997-01-01T23:59:59.000Z

302

Ultrasensitive Identification of Localization Variants of Modified Peptides Using Ion Mobility Spectrometry  

Science Conference Proceedings (OSTI)

Localization of the modification sites on peptides is challenging, particularly when multiple modifications or mixtures of localization isomers (variants) are involved. Such variants commonly coelute in liquid chromatography and may be undistinguishable in tandem mass spectrometry (MS/MS) for lack of unique fragments. Here, we have resolved the variants of singly and doubly phosphorylated peptides employing drift tube ion mobility spectrometry (IMS) coupled to time-of-flight mass spectrometry. Even with a moderate IMS resolving power of ~80, substantial separation was achieved for both 2+ and 3+ ions normally generated by electrospray ionization, including for the variant indistinguishable by MS/MS. Variants often exhibit a distribution of 3-D conformers, which can be adjusted for optimum IMS separation by prior field heating of ions in a funnel trap. The peak assignments were confirmed using MS/MS after IMS separation, but known species could be identified using just the ion mobility "tag". Avoiding the MS/MS step lowers the detection limit of localization variants to electron transfer dissociation in an Orbitrap MS.

Ibrahim, Yehia M.; Shvartsburg, Alexandre A.; Smith, Richard D.; Belov, Mikhail E.

2011-05-28T23:59:59.000Z

303

Beam Characterizations at Femtosecond Electron Beam Facility  

SciTech Connect

The SURIYA project at the Fast Neutron Research Facility (FNRF) has been established and is being commissioning to generate femtosecond (fs) electron bunches. Theses short bunches are produced by a system consisting of an S-band thermionic cathode RF-gun, an alpha magnet (a-magnet) serving as a magnetic bunch compressor, and a SLAC-type linear accelerator (linac). The characteristics of its major components and the beam characterizations as well as the preliminary experimental results will be presented and discussed in this paper.

Rimjaem, S.; Jinamoon, V.; Kangrang, M.; Kusoljariyakul, K.; Saisut, J.; Thongbai, C.; Vilaithong, T.; Rhodes, M.W.; Wichaisirimongkol, P.; /Chiang Mai U.; Wiedemann, H.; /SLAC

2006-03-17T23:59:59.000Z

304

Measurement of the Higgs Boson Mass with a Linear e+e- Collider  

E-Print Network (OSTI)

The potential of a linear e+e- collider operated at a centre-of-mass energy of 350 GeV is studied for the measurement of the Higgs boson mass. An integrated luminosity of 500 fb-1 is assumed. For Higgs boson masses of 120, 150 and 180 GeV the uncertainty on the Higgs boson mass measurement is estimated to be 40, 65 and 70 MeV, respectively. The effects of beam related systematics, namely a bias in the beam energy measurement, the beam energy spread and the luminosity spectrum due to beamstrahlung, on the precision of the Higgs boson mass measurement are investigated. In order to keep the systematic uncertainty on the Higgs boson mass well below the level of the statistical error, the beam energy measurement must be controlled with a relative precision better than 10-4.

P. Garcia-Abia; W. Lohmann; A. Raspereza

2005-05-30T23:59:59.000Z

305

ICFA Beam Dynamics Newsletter  

SciTech Connect

The Collider-Accelerator Department at Brookhaven National Laboratory is building a high-brightness 500 mA capable Energy Recovery Linac (ERL) as one of its main R&D thrusts towards eRHIC, the polarized electron - hadron collider as an upgrade of the operating RHIC facility. The ERL is in final assembly stages, with injection commisioning starting in October 2012. The objective of this ERL is to serve as a platform for R&D into high current ERL, in particular issues of halo generation and control, Higher-Order Mode (HOM) issues, coherent emissions for the beam and high-brightness, high-power beam generation and preservation. The R&D ERL features a superconducting laser-photocathode RF gun with a high quantum efficiency photoccathode served with a load-lock cathode delivery system, a highly damped 5-cell accelerating cavity, a highly flexible single-pass loop and a comprehensive system of beam instrumentation. In this ICFA Beam Dynamics Newsletter article we will describe the ERL in a degree of detail that is not usually found in regular publications. We will discuss the various systems of the ERL, following the electrons from the photocathode to the beam dump, cover the control system, machine protection etc and summarize with the status of the ERL systems.

Ben-Zvi I.; Kuczewski A.; Altinbas, Z.; Beavis, D.; Belomestnykh,; Dai, J. et al

2012-07-01T23:59:59.000Z

306

Booster gold beam injection efficiency and beam loss  

SciTech Connect

The Relativistic Heavy Ion Collider (RHIC) at the BNL requires the AGS to provide gold beam with the intensity of 10{sup 9} ions per bunch. Over the years, the Tandem Van de Graaff has provided steadily increasing intensity of gold ion beams to the AGS Booster. However, the gold ion beam injection efficiency at the Booster has been found to decrease with the rising intensity of injected beams. As the result, for Tandem beams of the highest intensity, the Booster late intensity is lower than with slightly lower intensity Tandem beam. In this article, the authors present two experiments associated with the Booster injection efficiency and beam intensity. One experiment looks at the Booster injection efficiency by adjusting the Tandem beam intensity, and another looks at the beam life time while scraping the beam in the Booster. The studies suggest that the gold beam injection efficiency at the AGS Booster is related to the beam loss in the ring, rather than the intensity of injected beam or circulating beam.

Zhang, S.Y.; Ahrens, L.A.

1998-08-01T23:59:59.000Z

307

Beam-Based Alignment  

NLE Websites -- All DOE Office Websites (Extended Search)

One: One: Single-Bunch Comparative Study of Three Algorithms Peter Tenenbaum LCC-Note-0013 17-February-1999 Abstract We describe the results of a series of simulation studies of beam-based alignment of the NLC main linacs using the program LIAR. Three algorithms for alignment of quadrupoles and girders are consid- ered: the algorithm used in the ZDR, the ZDR algorithm combined with a post-alignment MICADO operation, and an algorithm which requires no steering dipoles but requires twice as many alignment segments per linac as the ZDR algorithm. The third algorithm appears to be the most robust, based on convergence time, required quad mover step sizes, and variation in extracted beam emittance as a function of BNS profile. We also study the effect of structure BPM resolution and ATL misalignments during the alignment process. 1 Introduction Beam-based alignment and steering of the

308

Colliding Crystalline Beams  

SciTech Connect

Crystalline Beams* are an ordered state of an ensemble of ions, circulating in a storage ring, with very small velocity fluctuations. They can be obtained from ordinary warm ion beams with the application of powerful cooling techniques (stochastic, electron, laser, ...). Depending on the focussing properties and dimensions of the storage ring, and on the ion beam density, several ground states are possible. All of them can be visualized as a bundle of n{sub s} symmetrically distributed, parallel strings. The longitudinal ion separation {lambda} is the same for all strings. The minimum temperature that can be achieved depends on die background noise of the cooling technique used. It is required for stability that the vibration amplitude of the ions is only a fraction of the separation {lambda}.

Haffmans, A.F.; Maletic, D.; Ruggiero, A.G.

1995-06-01T23:59:59.000Z

309

BOOSTER GOLD BEAM INJECTION EFFICIENCY AND BEAM LOSS  

SciTech Connect

The Relativistic Heavy Ion Collider (RHIC) at the BNL requires the AGS to provide Gold beam with the intensity of 10{sup 9} ions per bunch. Over the years, the Tandem Van de Graaff has provided steadily increasing intensity of gold ion beams to the AGS Booster. However, the gold beam injection efficiency at the Booster has been found to decrease with the rising intensity of injected beams. As the result, for Tandem beams of the highest intensity, the Booster late intensity is lower than with slightly lower intensity Tandem beam. In this article, the authors present two experiments associated with the Booster injection efficiency and beam intensity. One experiment looks at the Booster injection efficiency by adjusting the Tandem beam intensity, and another looks at the beam life time while scraping the beam in the Booster. The studies suggest that the gold beam injection efficiency at the AGS Booster is related to the beam loss in the ring, rather than the intensity of injected beam or circulating beam. A close look at the effect of the lost gold ion at the Booster injection leads to the prediction that the lost gold ion creates large number of positive ions, and even larger number of electrons. The lost gold beam is also expected to create large numbers of neutral particles. In 1998 heavy ion run, the production of positive ions and electrons due to the lost gold beam has been observed. Also the high vacuum pressure due to the beam loss, presumably because of the neutral particles it created, has been measured. These results will be reported elsewhere.

ZHANG,S.Y.; AHRENS,L.A.

1998-06-22T23:59:59.000Z

310

Probing Organic Transistors with Infrared Beams  

NLE Websites -- All DOE Office Websites (Extended Search)

Probing Organic Transistors with Infrared Beams Print Probing Organic Transistors with Infrared Beams Print Silicon-based transistors are well-understood, basic components of contemporary electronic technology. In contrast, there is growing need for the development of electronic devices based on organic polymer materials. Organic field-effect transistors (FETs) are ideal for special applications that require large areas, light weight, and structural flexibility. They also have the advantage of being easy to mass-produce at very low cost. However, even though this class of devices is finding a growing number of applications, electronic processes in organic materials are still not well understood. A group of researchers from the University of California and the ALS has succeeded in probing the intrinsic electronic properties of the charge carriers in organic FETs using infrared spectromicroscopy. The results of their study could help in the future development of sensors, large-area displays, and other plastic electronic components.

311

Beam specie analyzer for intense neutral beams  

DOE Green Energy (OSTI)

A three-channel neutral particle energy analyzer has been fabricated and calibrated for H/sup 0/ particles. H/sup 0/ with energies 3.5-55 keV was passed through a N/sub 2/ gas cell maintained at charge equilibrium pressures. H/sup +/ ions formed by stripping collisions were energy analyzed by a 45/sup 0/, parabolic, electrostatic analyzer and detected by three Faraday cups spaced to intercept the full-, half-, and third-energy beam components. The conversion efficiency of the analyzer system increased from 0.11 at 3.5 keV to 0.54 at 55 keV with an accuracy of +- 3%.

Barnett, C.F.; Ray, J.A.

1981-03-01T23:59:59.000Z

312

Electron beam dynamics for the ISIS bremsstrahlung beam generation system  

E-Print Network (OSTI)

An electron beam transport system was designed for use in the Bremsstrahlung Beam Generation System of the Integrated Stand-off Inspection System (ISIS). The purpose of this electron transport system was to provide for ...

Block, Robert E. (Robert Edward)

2011-01-01T23:59:59.000Z

313

Beam current sensor  

DOE Patents (OSTI)

A current sensor for measuring the dc component of a beam of charged particles employs a superconducting pick-up loop probe, with twisted superconducting leads in combination with a Superconducting Quantum Interference Device (SQUID) detector. The pick-up probe is in the form of a single-turn loop, or a cylindrical toroid, through which the beam is directed and within which a first magnetic flux is excluded by the Meisner effect. The SQUID detector acts as a flux-to-voltage converter in providing a current to the pick-up loop so as to establish a second magnetic flux within the electrode which nulls out the first magnetic flux. A feedback voltage within the SQUID detector represents the beam current of the particles which transit the pick-up loop. Meisner effect currents prevent changes in the magnetic field within the toroidal pick-up loop and produce a current signal independent of the beam's cross-section and its position within the toroid, while the combination of superconducting elements provides current measurement sensitivities in the nano-ampere range.

Kuchnir, M.; Mills, F.E.

1984-09-28T23:59:59.000Z

314

Beam current sensor  

DOE Patents (OSTI)

A current sensor for measuring the DC component of a beam of charged particles employs a superconducting pick-up loop probe, with twisted superconducting leads in combination with a Superconducting Quantum Interference Device (SQUID) detector. The pick-up probe is in the form of a single-turn loop, or a cylindrical toroid, through which the beam is directed and within which a first magnetic flux is excluded by the Meisner effect. The SQUID detector acts as a flux-to-voltage converter in providing a current to the pick-up loop so as to establish a second magnetic flux within the electrode which nulls out the first magnetic flux. A feedback voltage within the SQUID detector represents the beam current of the particles which transit the pick-up loop. Meisner effect currents prevent changes in the magnetic field within the toroidal pick-up loop and produce a current signal independent of the beam's cross-section and its position within the toroid, while the combination of superconducting elements provides current measurement sensitivites in the nano-ampere range.

Kuchnir, Moyses (Elmhurst, IL); Mills, Frederick E. (Elburn, IL)

1987-01-01T23:59:59.000Z

315

Positive and Negative Ion Beam Merging System for Neutral Beam ...  

APPLICATIONS OF TECHNOLOGY: Semiconductor manufacturing; Low- and medium-energy ion implantation; Fusion plasma systems requiring neutral beam ...

316

Neutral particle beam intensity controller  

DOE Patents (OSTI)

A neutral beam intensity controller is provided for a neutral beam generator in which a neutral beam is established by accelerating ions from an ion source into a gas neutralizer. An amplitude modulated, rotating magnetic field is applied to the accelerated ion beam in the gas neutralizer to defocus the resultant neutral beam in a controlled manner to achieve intensity control of the neutral beam along the beam axis at constant beam energy. The rotating magnetic field alters the orbits of ions in the gas neutralizer before they are neutralized, thereby controlling the fraction of neutral particles transmitted out of the neutralizer along the central beam axis to a fusion device or the like. The altered path or defocused neutral particles are sprayed onto an actively cooled beam dump disposed perpendicular to the neutral beam axis and having a central open for passage of the focused beam at the central axis of the beamline. Virtually zero therough 100% intensity control is achieved by varying the magnetic field strength without altering the ion source beam intensity or its species yield.

Dagenhart, William K. (Oak Ridge, TN)

1986-01-01T23:59:59.000Z

317

Beam experiments towards high-intensity beams in RHIC  

SciTech Connect

Proton bunch intensities in RHIC are planned to be increased from 2 {center_dot} 10{sup 11} to 3 {center_dot} 10{sup 11} protons per bunch to increase the luminosity, together with head-on beam-beam compensation using electron lenses. To study the feasibility of the intensity increase, beam experiments are being performed. Recent experimental results are presented.

Montag C.; Ahrens, L.; Brennan, J.M.; Blaskiewicz, M.; Drees, A.; Fischer, W.; Hayes, T.; Huang, H.; Mernick, K.; Robert-Demolaize, G.; Smith, K.; Than, R.; Thieberger, P.; Yip, K.; Zeno, K.; Zhang, S.Y.

2012-05-20T23:59:59.000Z

318

High-energy accelerator for beams of heavy ions  

DOE Patents (OSTI)

An apparatus for accelerating heavy ions to high energies and directing the accelerated ions at a target comprises a source of singly ionized heavy ions of an element or compound of greater than 100 atomic mass units, means for accelerating the heavy ions, a storage ring for accumulating the accelerated heavy ions and switching means for switching the heavy ions from the storage ring to strike a target substantially simultaneously from a plurality of directions. In a particular embodiment the heavy ion that is accelerated is singly ionized hydrogen iodide. After acceleration, if the beam is of molecular ions, the ions are dissociated to leave an accelerated singly ionized atomic ion in a beam. Extraction of the beam may be accomplished by stripping all the electrons from the atomic ion to switch the beam from the storage ring by bending it in magnetic field of the storage ring.

Martin, Ronald L. (La Grange, IL); Arnold, Richard C. (Chicago, IL)

1978-01-01T23:59:59.000Z

319

Pushing the Frontier of High-Definition Ion Mobility Spectrometry Using FAIMS  

Science Conference Proceedings (OSTI)

Differential ion mobility spectrometry (FAIMS) separates ions in gases based on the difference between their mobilities in strong and weak electric fields, captured directly employing a periodic waveform with dissimilar profiles in opposite polarities. As that difference is not tightly correlated with the ion size or mass, FAIMS separations are generally quite orthogonal to both conventional IMS (based on the absolute ion mobility that reflects the physical ion size) and mass spectrometry (based on mass). Until a few years ago, that advantage was largely offset by poor FAIMS resolving power (?10–20), an order of magnitude below that achieved with conventional (drift-tube) IMS. This article summarizes the major recent technical developments that have raised FAIMS resolving power up to ?500. These include use of higher and more stable voltages provided by new waveform generators, novel buffer gas compositions comprising high helium or hydrogen fractions, and extended filtering times up to ?1 s. These advances have enabled previously unthinkable analyses such as broad baseline separations of peptide sequence inversions, localization variants (post-translationally modified peptides with differing PTM attachment sites) even for the larger “middle-down” peptides and smallest PTMs, and lipid regioisomers.

Shvartsburg, Alexandre A.; Anderson, Gordon A.; Smith, Richard D.

2013-05-03T23:59:59.000Z

320

Focused ion beam direct fabrication of micro-optical elements: features compared with laser beam and electron beam direct writing  

E-Print Network (OSTI)

Three types of focused ion beam machine: focused ion beam milling (FIB milling), focused ion beam lithography (FIB lithography), and focused ion beam direct deposition (FIB deposition), are described in detail to compare ...

Fu, Yongqi

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Dependence of the Photon Beam Characteristics on Electron Beam Parameters in Third Generation Synchrotron Light Sources  

E-Print Network (OSTI)

Dependence of the Photon Beam Characteristics on Electron Beam Parameters in Third Generation Synchrotron Light Sources

Ivanyan, M I; Tsakanov, V M

2002-01-01T23:59:59.000Z

322

Beam-stack search: Integrating backtracking with beam search  

E-Print Network (OSTI)

We describe a method for transforming beam search into a complete search algorithm that is guaranteed to find an optimal solution. Called beam-stack search, the algorithm uses a new data structure, called a beam stack, that makes it possible to integrate systematic backtracking with beam search. The resulting search algorithm is an anytime algorithm that finds a good, sub-optimal solution quickly, like beam search, and then backtracks and continues to find improved solutions until convergence to an optimal solution. We describe a memory-efficient implementation of beam-stack search, called divide-and-conquer beam-stack search, as well as an iterative-deepening version of the algorithm. The approach is applied to domain-independent STRIPS planning, and computational results show its advantages.

Rong Zhou; Eric A. Hansen

2005-01-01T23:59:59.000Z

323

Physics with Rare Isotope Beams  

Science Conference Proceedings (OSTI)

Using stable and radioactive beams provided by ATLAS nuclear reactions of special interest in astrophysics have been studied with emphasis on breakout from the hot CNO cycle to the rp-process. The masses of nuclear fragments provided by a strong fission source have been measured in order to help trace the path of the r process. 8Li ions produced by the d(7Li,8Li)n reaction have been trapped and the electrons and alphas emitted in the ensuing beta-decay measured. The neutrino directions were therefore determined, which leads to a measurement of the electron-neutrino correlation. The energies and kinematics are such that a sensitive search for any tensor admixture could be performed and an upper limit of 0.6% was placed on any such admixture. Earlier work on the electromagnetic form factors of the proton was extended. Graduate students were active participants in all of these eperiments, which formed the basis for six PhD theses.

Segel, Ralph E. [Northwestern University

2013-11-08T23:59:59.000Z

324

Laser beam guard clamps  

DOE Patents (OSTI)

A quick insert and release laser beam guard panel clamping apparatus having a base plate mountable on an optical table, a first jaw affixed to the base plate, and a spring-loaded second jaw slidably carried by the base plate to exert a clamping force. The first and second jaws each having a face acutely angled relative to the other face to form a V-shaped, open channel mouth, which enables wedge-action jaw separation by and subsequent clamping of a laser beam guard panel inserted through the open channel mouth. Preferably, the clamping apparatus also includes a support structure having an open slot aperture which is positioned over and parallel with the open channel mouth.

Dickson, Richard K. (Stockton, CA)

2010-09-07T23:59:59.000Z

325

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1-5 1-5 Nov. 05, 2007 Nov. 06, 2007 Nov. 07, 2007 Nov. 08, 2007 Nov. 09, 2007 Nov. 10, 2007 Nov. 11, 2007 Unscheduled FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI BEAM LINE 7-1 Nov. 05, 2007 Nov. 06, 2007 Nov. 07, 2007 Nov. 08, 2007 Nov. 09, 2007 Nov. 10, 2007 Nov. 11, 2007 Unscheduled FACI FACI FACI FACI FACI FACI

326

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

4 4 Mar. 15, 2004 Mar. 16, 2004 Mar. 17, 2004 Mar. 18, 2004 Mar. 19, 2004 Mar. 20, 2004 Mar. 21, 2004 DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN BEAM LINE 1-5 Mar. 15, 2004 Mar. 16, 2004 Mar. 17, 2004 Mar. 18, 2004 Mar. 19, 2004 Mar. 20, 2004 Mar. 21, 2004 DOWN DOWN DOWN DOWN DOWN DOWN DOWN

327

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

5-1 5-1 Nov. 28, 2005 Nov. 29, 2005 Nov. 30, 2005 Dec. 01, 2005 Dec. 02, 2005 Dec. 03, 2005 Dec. 04, 2005 MA FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI BEAM LINE 5-2 Nov. 28, 2005 Nov. 29, 2005 Nov. 30, 2005 Dec. 01, 2005 Dec. 02, 2005 Dec. 03, 2005 Dec. 04, 2005 MA FACI FACI FACI FACI FACI FACI

328

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1-5 1-5 Nov. 10, 2008 Nov. 11, 2008 Nov. 12, 2008 Nov. 13, 2008 Nov. 14, 2008 Nov. 15, 2008 Nov. 16, 2008 DOWN FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI FACI BEAM LINE 7-1 Nov. 10, 2008 Nov. 11, 2008 Nov. 12, 2008 Nov. 13, 2008 Nov. 14, 2008 Nov. 15, 2008 Nov. 16, 2008 DOWN FACI FACI FACI FACI FACI FACI

329

Ion beam generating apparatus  

DOE Patents (OSTI)

An ion generating apparatus utilizing a vacuum chamber, a cathode and an anode in the chamber. A source of electrical power produces an arc or discharge between the cathode and anode. The arc is sufficient to vaporize a portion of the cathode to form a plasma. The plasma is directed to an extractor which separates the electrons from the plasma, and accelerates the ions to produce an ion beam.

Brown, Ian G. (1088 Woodside Rd., Berkeley, CA 94708); Galvin, James (2 Commodore #276, Emeryville, CA 94608)

1987-01-01T23:59:59.000Z

330

Ion beam generating apparatus  

DOE Patents (OSTI)

An ion generating apparatus utilizing a vacuum chamber, a cathode and an anode in the chamber. A source of electrical power produces an arc or discharge between the cathode and anode. The arc is sufficient to vaporize a portion of the cathode to form a plasma. The plasma is directed to an extractor which separates the electrons from the plasma, and accelerates the ions to produce an ion beam. 10 figs.

Brown, I.G.; Galvin, J.

1987-12-22T23:59:59.000Z

331

Relativistic electron beam device  

DOE Patents (OSTI)

A design is given for an electron beam device for irradiating spherical hydrogen isotope bearing targets. The accelerator, which includes hollow cathodes facing each other, injects an anode plasma between the cathodes and produces an approximately 10 nanosecond, megajoule pulse between the anode plasma and the cathodes. Targets may be repetitively positioned within the plasma between the cathodes, and accelerator diode arrangement permits materials to survive operation in a fusion power source. (auth)

Freeman, J.R.; Poukey, J.W.; Shope, S.L.; Yonas, G.

1975-07-01T23:59:59.000Z

332

Stationary nonlinear Airy beams  

Science Conference Proceedings (OSTI)

We demonstrate the existence of an additional class of stationary accelerating Airy wave forms that exist in the presence of third-order (Kerr) nonlinearity and nonlinear losses. Numerical simulations and experiments, in agreement with the analytical model, highlight how these stationary solutions sustain the nonlinear evolution of Airy beams. The generic nature of the Airy solution allows extension of these results to other settings, and a variety of applications are suggested.

Lotti, A. [Dipartimento di Fisica e Matematica, Universita del'Insubria, Via Valleggio 11, I-22100 Como (Italy); Centre de Physique Theorique, CNRS, Ecole Polytechnique, F-91128 Palaiseau (France); Faccio, D. [Dipartimento di Fisica e Matematica, Universita del'Insubria, Via Valleggio 11, I-22100 Como (Italy); School of Engineering and Physical Sciences, SUPA, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); Couairon, A. [Centre de Physique Theorique, CNRS, Ecole Polytechnique, F-91128 Palaiseau (France); Papazoglou, D. G. [Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology, Hellas (FORTH), P.O. Box 1527, GR-71110 Heraklion (Greece); Materials Science and Technology Department, University of Crete, GR-71003 Heraklion (Greece); Panagiotopoulos, P.; Tzortzakis, S. [Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology, Hellas (FORTH), P.O. Box 1527, GR-71110 Heraklion (Greece); Abdollahpour, D. [Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology, Hellas (FORTH), P.O. Box 1527, GR-71110 Heraklion (Greece); Physics Department, University of Crete, GR-71003 Heraklion (Greece)

2011-08-15T23:59:59.000Z

333

Mercury's Protoplanetary Mass  

E-Print Network (OSTI)

Major element fractionation among chondrites has been discussed for decades as ratios relative to Si or Mg. Recently, by expressing ratios relative to Fe, I discovered a new relationship admitting the possibility that ordinary chondrite meteorites are derived from two components, a relatively oxidized and undifferentiated, primitive component and a somewhat differentiated, planetary component, with oxidation state like the highly reduced enstatite chondrites, which I suggested was identical to Mercury's complement of lost elements. Here, on the basis of that relationship, I derive expressions, as a function of the mass of planet Mercury and the mass of its core, to estimate the mass of Mercury's lost elements, the mass of Mercury's alloy and rock protoplanetary core, and the mass of Mercury's gaseous protoplanet. Although Mercury's mass is well known, its core mass is not, being widely believed to be in the range of 70-80 percent of the planet mass. For a core mass of 75 percent, the mass of Mercury's lost elements is about 1.32 times the mass of Mercury, the mass of the alloy and rock protoplanetary core is about 2.32 times the mass of Mercury, and the mass of the gaseous protoplanet of Mercury is about 700 times the mass of Mercury. Circumstantial evidence is presented in support of the supposition that Mercury's lost elements is identical to the planetary component of ordinary chondrite formation.

J. Marvin Herndon

2004-10-01T23:59:59.000Z

334

Volatiles in hydrothermal fluids- A mass spectrometric study of fluid  

Open Energy Info (EERE)

Volatiles in hydrothermal fluids- A mass spectrometric study of fluid Volatiles in hydrothermal fluids- A mass spectrometric study of fluid inclusions from active geothermal systems Jump to: navigation, search GEOTHERMAL ENERGYGeothermal Home Report: Volatiles in hydrothermal fluids- A mass spectrometric study of fluid inclusions from active geothermal systems Details Activities (4) Areas (4) Regions (0) Abstract: A system for analysis of inclusion gas contents based upon quadrupole mass spectrometry has been designed, assembled and tested during the first 7 months of funding. The system is currently being tested and calibrated using inclusions with known gas contents from active geothermal systems. Analyses are in progress on inclusions from the Salton Sea, Valles Caldera, Geysers, and Coso geothermal systems. Author(s): Mckibben, M. A.

335

Beam-Beam Interaction Simulations with Guinea Pig  

NLE Websites -- All DOE Office Websites (Extended Search)

5 5 SLAC-TN-03-070 September 2003 Beam-Beam Interaction Simulations with Guinea Pig C. Sramek, T. O. Raubenheimer, A. Seryi, M. Woods, J. Yu Stanford Linear Accelerator Center Stanford University Stanford, CA Abstract: At the interaction point of a particle accelerator, various phenomena occur that are known as beam-beam effects. Incident bunches of electrons (or positrons) experience strong electromagnetic fields from the opposing bunches, which leads to electron deflection, beamstrahlung and the creation of electron/positron pairs and hadrons due to two-photon exchange. In addition, the beams experience a "pinch effect" which focuses each beam and results in either a reduction or expansion of their vertical size. Finally, if a

336

BEAM HALO FORMATION IN HIGH-INTENSITY BEAMS.  

SciTech Connect

Studies of beam halo became unavoidable feature of high-intensity machines where uncontrolled beam loss should be kept to extremely small level. For a well controlled stable beam such a loss is typically associated with the low density halo surrounding beam core. In order to minimize uncontrolled beam loss or improve performance of an accelerator, it is very important to understand what are the sources of halo formation in a specific machine of interest. The dominant mechanisms are, in fact, different in linear accelerators, circular machines or Energy Recovering Linacs (ERL). In this paper, we summarize basic mechanisms of halo formation in high-intensity beams and discuss their application to various types of accelerators of interest, such as linacs, rings and ERL.

FEDOTOV, A.V.

2005-03-18T23:59:59.000Z

337

A low energy beam transport system for proton beam  

SciTech Connect

A low energy beam transport (LEBT) system has been built for a compact pulsed hadron source (CPHS) at Tsinghua University in China. The LEBT, consisting of two solenoids and three short-drift sections, transports a pulsed proton beam of 60 mA of energy of 50 keV to the entrance of a radio frequency quadrupole (RFQ). Measurement has shown a normalized RMS beam emittance less than 0.2 {pi} mm mrad at the end of the LEBT. Beam simulations were carried out to compare with the measurement and are in good agreement. Based on the successful CPHS LEBT development, a new LEBT for a China ADS projector has been designed. The features of the new design, including a beam chopper and beam simulations of the LEBT are presented and discussed along with CPHS LEBT development in this article.

Yang, Y. [Institute of Modern Physics, CAS, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100039 (China); Zhang, Z. M.; Wu, Q.; Zhang, W. H.; Ma, H. Y.; Sun, L. T.; Zhang, X. Z.; Liu, Z. W.; He, Y.; Zhao, H. W.; Xie, D. Z. [Institute of Modern Physics, CAS, Lanzhou 730000 (China)

2013-03-15T23:59:59.000Z

338

A Scanning Frequency Mode for Ion Cyclotron Mobility Spectrometry  

E-Print Network (OSTI)

A new operational mode for an ion cyclotron mobility spectrometry instrument is explored as a possibleA Scanning Frequency Mode for Ion Cyclotron Mobility Spectrometry Rebecca S. Glaskin, Stephen J that are applied to segmented regions of a circular drift tube. Ions with mobilities that are resonant

Clemmer, David E.

339

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1-4 1-4 Oct. 30, 2006 Oct. 31, 2006 Nov. 01, 2006 Nov. 02, 2006 Nov. 03, 2006 Nov. 04, 2006 Nov. 05, 2006 DOWN Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled BEAM LINE 2-1 Oct. 30, 2006 Oct. 31, 2006 Nov. 01, 2006 Nov. 02, 2006 Nov. 03, 2006 Nov. 04, 2006 Nov. 05, 2006 DOWN 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON

340

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

5 5 Mar. 15, 2004 Mar. 16, 2004 Mar. 17, 2004 Mar. 18, 2004 Mar. 19, 2004 Mar. 20, 2004 Mar. 21, 2004 DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN DOWN BEAM LINE 9-1 Mar. 15, 2004 Mar. 16, 2004 Mar. 17, 2004 Mar. 18, 2004 Mar. 19, 2004 Mar. 20, 2004 Mar. 21, 2004 Unscheduled CHANGE/8837 A.COHE 8837 A.COHEN 8837 A.COHEN 8837 A.COHEN 8837 A.COHEN 8837 A.COHEN

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

edited1_TopQuarkMass  

NLE Websites -- All DOE Office Websites (Extended Search)

CALCULATE THE TOP QUARK MASS CALCULATE THE TOP QUARK MASS TEACHER NOTES DESCRIPTION Students use momentum conservation, energy conservation and two-dimensional vector addition to calculate the mass of the heaviest of the six known quarks. They gather data from data plots from the DØ experiment at Fermilab. The events were chosen carefully; all of the decay products moved in a plane perpendicular to the beam. This makes the vector addition much simpler. STANDARDS National Science Education Standards (U.S. National Research Council) * Physical Science Content Standard B: As a result of this activity . . . students should develop an understanding of: o Conservation of energy and increase in disorder. o Interactions in energy and matter. LEARNING OBJECTIVES Students will know and be able to:

342

Precision Absolute Beam Current Measurement of Low Power Electron Beam  

SciTech Connect

Precise measurements of low power CW electron beam current for the Jefferson Lab Nuclear Physics program have been performed using a Tungsten calorimeter. This paper describes the rationale for the choice of the calorimeter technique, as well as the design and calibration of the device. The calorimeter is in use presently to provide a 1% absolute current measurement of CW electron beam with 50 to 500 nA of average beam current and 1-3 GeV beam energy. Results from these recent measurements will also be presented.

Ali, M. M.; Bevins, M. E.; Degtiarenko, P.; Freyberger, A.; Krafft, G. A.

2012-11-01T23:59:59.000Z

343

Higgs Recoil Mass and Higgs-Strahlung Cross-Section Study for the ILD LOI  

E-Print Network (OSTI)

This proceeding summarizes the Higgs recoil mass and Higgs-strahlung cross-section study done for the Letter of Intent (LOI) of the International Large Detector (ILD) Concept. Assuming a Higgs mass of 120 GeV, working at 250 GeV center of mass energy with beam parameters RDR250 and beam polarization, this full simulation study predicts that, the ILD detector can achieve 37 MeV precision on the Higgs mass measurement and 3.3% on the cross-section measurement from the muon channel, while 83 MeV and 4.9% from the electron channel, if we have 250 inverse fb integrated luminosity.

Hengne Li

2010-07-18T23:59:59.000Z

344

Magnetically operated beam dump for dumping high power beams in a neutral beamline  

DOE Patents (OSTI)

It is an object of this invention to provide a beam dump system for a neutral beam generator which lowers the time-averaged power density of the beam dump impingement surface. Another object of this invention is to provide a beam dump system for a neutral particle beam based on reionization and subsequent magnetic beam position modulation of the beam onto a beam dump surface to lower the time-averaged power density of the beam dump ion impingement surface.

Dagenhart, W.K.

1984-01-27T23:59:59.000Z

345

LANL: Ion Beam Materials Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Ion Beam Materials Laboratory (IBML) is a Los Ion Beam Materials Laboratory (IBML) is a Los Alamos National Laboratory resource devoted to materi- als research through the use of ion beams. Current major research areas include surface characterization through ion beam analysis techniques, surface modification and materials synthesis through ion implantation technology, and radiation damage stud- ies in gases, liquids, and solids. The laboratory's core is a 3.2 MV tandem ion accelerator and a 200 kV ion implanter together with several beam lines. Attached to each beam line is a series of experimental stations that support various research programs. The operation of IBML and its interactions with users are organized around core facilities and experimental stations. The IBML provides and operates the core facilities as well as supports

346

Beam-line cryopump  

DOE Green Energy (OSTI)

A cryopumping module using metallic surfaces at liquid helium temperature for condensation of hydrogen and deuterium gas has been constructed. This pump, a prototype of four units which will provide pumping for the Livermore 200 kV test stand, will be used to verify the concept and establish engineering parameters. Upon completion of engineering tests and evaluation the pump will be installed in an operating beam line. The design point pumping capacity is 80,000 liters per second for hydrogen and deuterium at 10$sup -4$ torr based on sticking coefficients of 0.15 and 0.25, respectively. Both the liquid helium temperature pumping surface and the liquid nitrogen temperature radiation shields are constructed of quilted double wall cylindrical shells. The pumping shell dimensions are 1.5 meters dia. x 0.6 meters long. Cryogen circulation is convection current driven in both cases. Liquid helium is supplied from an overhead Dewar through bayonet coupling. In the 200 kV beam line, pumping modules will be supplied via transfer lines from a central Dewar. Voltage standoff will be accomplished in the transfer lines. (auth)

Duffy, T.J.; Oddon, L.D.

1975-11-12T23:59:59.000Z

347

Beam emittance measurements at Fermilab  

Science Conference Proceedings (OSTI)

We give short overview of various beam emittance measurement methods, currently applied at different machine locations for the Run II collider physics program at Fermilab. All these methods are based on beam profile measurements, and we give some examples of the related instrumentation techniques. At the end we introduce a multi-megawatt proton source project, currently under investigation at Fermilab, with respect to the beam instrumentation challenges.

Wendt, Manfred; Eddy, Nathan; Hu, Martin; Scarpine, Victor; Syphers, Mike; Tassotto, Gianni; Thurman-Keup, Randy; Yang, Ming-Jen; Zagel, James; /Fermilab

2008-01-01T23:59:59.000Z

348

A pencil beam algorithm for helium ion beam therapy  

Science Conference Proceedings (OSTI)

Purpose: To develop a flexible pencil beam algorithm for helium ion beam therapy. Dose distributions were calculated using the newly developed pencil beam algorithm and validated using Monte Carlo (MC) methods. Methods: The algorithm was based on the established theory of fluence weighted elemental pencil beam (PB) kernels. Using a new real-time splitting approach, a minimization routine selects the optimal shape for each sub-beam. Dose depositions along the beam path were determined using a look-up table (LUT). Data for LUT generation were derived from MC simulations in water using GATE 6.1. For materials other than water, dose depositions were calculated by the algorithm using water-equivalent depth scaling. Lateral beam spreading caused by multiple scattering has been accounted for by implementing a non-local scattering formula developed by Gottschalk. A new nuclear correction was modelled using a Voigt function and implemented by a LUT approach. Validation simulations have been performed using a phantom filled with homogeneous materials or heterogeneous slabs of up to 3 cm. The beams were incident perpendicular to the phantoms surface with initial particle energies ranging from 50 to 250 MeV/A with a total number of 10{sup 7} ions per beam. For comparison a special evaluation software was developed calculating the gamma indices for dose distributions. Results: In homogeneous phantoms, maximum range deviations between PB and MC of less than 1.1% and differences in the width of the distal energy falloff of the Bragg-Peak from 80% to 20% of less than 0.1 mm were found. Heterogeneous phantoms using layered slabs satisfied a {gamma}-index criterion of 2%/2mm of the local value except for some single voxels. For more complex phantoms using laterally arranged bone-air slabs, the {gamma}-index criterion was exceeded in some areas giving a maximum {gamma}-index of 1.75 and 4.9% of the voxels showed {gamma}-index values larger than one. The calculation precision of the presented algorithm was considered to be sufficient for clinical practice. Although only data for helium beams was presented, the performance of the pencil beam algorithm for proton beams was comparable. Conclusions: The pencil beam algorithm developed for helium ions presents a suitable tool for dose calculations. Its calculation speed was evaluated to be similar to other published pencil beam algorithms. The flexible design allows easy customization of measured depth-dose distributions and use of varying beam profiles, thus making it a promising candidate for integration into future treatment planning systems. Current work in progress deals with RBE effects of helium ions to complete the model.

Fuchs, Hermann; Stroebele, Julia; Schreiner, Thomas; Hirtl, Albert; Georg, Dietmar [Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna, 1090 Vienna (Austria); Department of Radiation Oncology, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria) and Comprehensive Cancer Center, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria); Department of Radiation Oncology, Medical University of Vienna/AKH Vienna (Austria) and Comprehensive Cancer Center, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria); PEG MedAustron, 2700 Wiener Neustadt (Austria); Department of Nuclear Medicine, Medical University of Vienna, 1090 Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna, 1090 Vienna (Austria); Department of Radiation Oncology, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria) and Comprehensive Cancer Center, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria)

2012-11-15T23:59:59.000Z

349

Broad-band beam buncher  

DOE Patents (OSTI)

A broad-band beam buncher is disclosed, comprising an evacuated housing, an electron gun therein for producing an electron beam, a buncher cavity having entrance and exit openings through which the beam is directed, grids across such openings, a source providing a positive DC voltage between the cavity and the electron gun, a drift tube through which the electron beam travels in passing through such cavity, grids across the ends of such drift tube, gaps being provided between the drift tube grids and the entrance and exit grids, a modulator for supplying an ultrahigh frequency modulating signal to the drift tube for producing velocity modulation of the electrons in the beam, a drift space in the housing through which the velocity modulated electron beam travels and in which the beam is bunched, and a discharge opening from such drift tube and having a grid across such opening through which the bunched electron beam is discharged into an accelerator or the like. The buncher cavity and the drift tube may be arranged to constitute an extension of a coaxial transmission line which is employed to deliver the modulating signal from a signal source. The extended transmission line may be terminated in its characteristic impedance to afford a broad-band response and the device as a whole designed to effect broad-band beam coupling, so as to minimize variations of the output across the response band.

Goldberg, David A. (Walnut Creek, CA); Flood, William S. (Berkeley, CA); Arthur, Allan A. (Martinez, CA); Voelker, Ferdinand (Orinda, CA)

1986-01-01T23:59:59.000Z

350

Electron Beam Melting (EBM) II  

Science Conference Proceedings (OSTI)

Oct 19, 2011 ... Additive Manufacturing of Metals: Electron Beam Melting (EBM) II Sponsored by: MS&T Organization Program Organizers: Ian D. Harris, EWI; ...

351

Development of high-spatial and high-mass resolution mass spectrometric imaging (MSI) and its application to the study of small metabolites and endogenous molecules of plants  

SciTech Connect

High-spatial and high-mass resolution laser desorption ionization (LDI) mass spectrometric (MS) imaging technology was developed for the attainment of MS images of higher quality containing more information on the relevant cellular and molecular biology in unprecedented depth. The distribution of plant metabolites is asymmetric throughout the cells and tissues, and therefore the increase in the spatial resolution was pursued to reveal the localization of plant metabolites at the cellular level by MS imaging. For achieving high-spatial resolution, the laser beam size was reduced by utilizing an optical fiber with small core diameter (25 ?m) in a vacuum matrix-assisted laser desorption ionization-linear ion trap (vMALDI-LTQ) mass spectrometer. Matrix application was greatly improved using oscillating capillary nebulizer. As a result, single cell level spatial resolution of ~ 12 ?m was achieved. MS imaging at this high spatial resolution was directly applied to a whole Arabidopsis flower and the substructures of an anther and single pollen grains at the stigma and anther were successfully visualized. MS imaging of high spatial resolution was also demonstrated to the secondary roots of Arabidopsis thaliana and a high degree of localization of detected metabolites was successfully unveiled. This was the first MS imaging on the root for molecular species. MS imaging with high mass resolution was also achieved by utilizing the LTQ-Orbitrap mass spectrometer for the direct identification of the surface metabolites on the Arabidopsis stem and root and differentiation of isobaric ions having the same nominal mass with no need of tandem mass spectrometry (MS/MS). MS imaging at high-spatial and high-mass resolution was also applied to cer1 mutant of the model system Arabidopsis thaliana to demonstrate its usefulness in biological studies and reveal associated metabolite changes in terms of spatial distribution and/or abundances compared to those of wild-type. The spatial distribution of targeted metabolites, mainly waxes and flavonoids, was systematically explored on various organs, including flowers, leaves, stems, and roots at high spatial resolution of ~ 12-50 ?m and the changes in the abundance level of these metabolites were monitored on the cer1 mutant with respect to the wild-type. This study revealed the metabolic biology of CER1 gene on each individual organ level with very detailed high spatial resolution. The separate MS images of isobaric metabolites, i.e. C29 alkane vs. C28 aldehyde could be constructed on both genotypes from MS imaging at high mass resolution. This allows tracking of abundance changes for those compounds along with the genetic mutation, which is not achievable with low mass resolution mass spectrometry. This study supported previous hypothesis of molecular function of CER1 gene as aldehyde decarbonylase, especially by displaying hyper accumulation of aldehydes and C30 fatty acid and decrease in abundance of alkanes and ketones in several plant organs of cer1 mutant. The scope of analytes was further directed toward internal cell metabolites from the surface metabolites of the plant. MS profiling and imaging of internal cell metabolites were performed on the vibratome section of Arabidopsis leaf. Vibratome sectioning of the leaf was first conducted to remove the surface cuticle layer and it was followed by enzymatic treatment of the section to induce the digestion of primary cell walls, middle lamella, and expose the internal cells underneath to the surface for detection with the laser by LDI-MS. The subsequent MS imaging onto the enzymatically treated vibratome section allowed us to map the distribution of the metabolites in the internal cell layers, linolenic acid (C18:3 FA) and linoleic acid (C18:2 FA). The development of an assay for relative quantification of analytes at the single subcellular/organelle level by LDI-MS imaging was attempted and both plausibility and significant obstacles were seen. As a test system, native plant organelle, chloroplasts isolated from the spinach leaves were used

Jun, Ji Hyun

2011-11-30T23:59:59.000Z

352

Elbow mass flow meter  

SciTech Connect

Elbow mass flow meter. The present invention includes a combination of an elbow pressure drop generator and a shunt-type mass flow sensor for providing an output which gives the mass flow rate of a gas that is nearly independent of the density of the gas. For air, the output is also approximately independent of humidity.

McFarland, Andrew R. (College Station, TX); Rodgers, John C. (Santa Fe, NM); Ortiz, Carlos A. (Bryan, TX); Nelson, David C. (Santa Fe, NM)

1994-01-01T23:59:59.000Z

353

Computational mass spectrometry : algorithms for identification of peptides not present in protein databases  

E-Print Network (OSTI)

Pereira, W. -T. Liu, J. Ng, P. A. Pevzner, P. C. Dorrestein,11188, 2010. W. -T. Liu, J. Ng, D. Meluzzi, N. Bandeira, M.no. 11, pp. 4200-4209, J. Ng, N. Bandeira, W. -T. Liu, M.

Ng, Julio

2011-01-01T23:59:59.000Z

354

A Mass Spectrometry Study of Isotope Separation in the Laser Plume  

E-Print Network (OSTI)

Pakistan is exacerbated by concerns over both terrorist activity and the security of its rapidly increasing nuclear

Suen, Timothy Wu

2012-01-01T23:59:59.000Z

355

Kinetics of laser pulse vaporization of uranium dioxide by mass spectrometry  

Science Conference Proceedings (OSTI)

Safety analyses of nuclear reactors require knowledge of the evaporation behavior of UO/sub 2/ at temperatures well above the melting point of 3140 K. In this study, rapid transient heating of a small spot on a UO/sub 2/ specimen was accomplished by a laser pulse, which generates a surface temperature excursion. This in turn vaporizes the target surface and the gas expands into vacuum. The surface temperature transient was monitored by a fast-response automatic optical pyrometer. The maximum surface temperatures investigated range from approx. 3700 K to approx. 4300 K. A computer program was developed to simulate the laser heating process and calculate the surface temperature evolution. The effect of the uncertainties of the high temperature material properties on the calculation was included in a sensitivity study for UO/sub 2/ vaporization. The measured surface temperatures were in satisfactory agreements.

Tsai, C.

1981-11-01T23:59:59.000Z

356

Mass Spectrometry Based Method Development for Elucidation of Protein Sequences, Structures and Post Translational Modifications  

E-Print Network (OSTI)

Covelli, I. ; Wolff, J. J. Bio. Chem. 1967, 242, 881-886.A. ; Yates, J. R. Curr. Opin. Chem. Bio. 2008, 12, 483-490.

Sun, Qingyu

2011-01-01T23:59:59.000Z

357

Application of Mass Spectrometry on Quantitative Proteomics and Histone Post-Translational Modifications  

E-Print Network (OSTI)

Probable ATP-dependent RNA helicase DDX5 IPI00220373.3Probable ATP-dependent RNA helicase DDX5 IPI00023748.3IPI00215637.4 ATP-dependent RNA helicase DDX3X IPI00010700.2

Xiong, Lei

2011-01-01T23:59:59.000Z

358

A Mass Spectrometry Study of Isotope Separation in the Laser Plume  

E-Print Network (OSTI)

Attribution and Non-Proliferation Applications”, IEEETreaty on the Non-Proliferation of Nuclear Weapons (NPT)”,as detailed in the Non-Proliferation Treaty (NPT), is to

Suen, Timothy Wu

2012-01-01T23:59:59.000Z

359

Accelerator Mass Spectrometry | U.S. DOE Office of Science (SC...  

Office of Science (SC) Website

important application of AMS measurements of the naturally occurring 36ClCl ratio in water (as opposed to the one created by atmospheric and underground nuclear weapons test) is...

360

Development and application of mass spectrometry-based metabolomics methods for disease biomarker identification  

E-Print Network (OSTI)

Human societies face diverse health challenges including a rapidly aging population, rising incidence of metabolic disease, and increasing antibiotic resistance. These problems involve complex interactions between genes ...

Tong, Lily Victoria

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

New mass spectrometry techniques for studying physical chemistry of atmospheric heterogeneous processes  

E-Print Network (OSTI)

ion mode DESI and nano-DESI result in the formation of protonated molecules [M + H]+ and molecules cationised on metals, such as sodium [M + Na]+ adducts, while deprotonated [M Ã? H]Ã? molecules are observed+ ) reacts selectively with molecules (M) containing carbonyl groups, such as aldehydes and ketones [79

Nizkorodov, Sergey

362

Thermogravimetry-Mass Spectrometry for Carbon Nanotube Detection in Complex Mixtures  

E-Print Network (OSTI)

In spite of the growth of the carbon nanotube (CNT) industry, there are no established analytical methods with which to detect or quantify CNTs in environmental matrices. Given that CNTs have relatively high thermal ...

Plata, Desiree Louise

363

Facilitation of protein 3-D structure determination using enhanced peptide amide deuterium exchange mass spectrometry (DXMS)  

E-Print Network (OSTI)

metalloproteinase inhibitor doxycycline investigated bymetalloproteinase inhibitor doxycycline investigated byand Nagasue N (2004) Doxycycline inhibits cell proliferation

Pantazatos, Dennis Peter

2006-01-01T23:59:59.000Z

364

A Mass Spectrometry Study of Isotope Separation in the Laser Plume  

E-Print Network (OSTI)

Proliferation of Nuclear Weapons (NPT)”, http: //www.un.org/end of the Cold War, nuclear weapons remain at the heart ofthe spread of nuclear weapons, analysis of nuclear materials

Suen, Timothy Wu

2012-01-01T23:59:59.000Z

365

Science of Signatures Workshop on Secondary Ion Mass Spectrometry (SIMS) Applications July 24, 2012  

SciTech Connect

The science of signatures focus areas are: (1) Radiological and Nuclear; (2) Chemical and Materials (including explosives); (3) Biological - Signatures of Disease and Health; (4) Energy; (5) Climate; and (6) Space.

Hickmott, Donald D [Los Alamos National Laboratory; Riciputi, Lee D [Los Alamos National Laboratory

2012-07-23T23:59:59.000Z

366

High resolution mass spectrometry method and system for analysis of whole proteins and other large molecules  

DOE Patents (OSTI)

A matrix assisted laser desorption/ionization (MALDI) method and related system for analyzing high molecular weight analytes includes the steps of providing at least one matrix-containing particle inside an ion trap, wherein at least one high molecular weight analyte molecule is provided within the matrix-containing particle, and MALDI on the high molecular weight particle while within the ion trap. A laser power used for ionization is sufficient to completely vaporize the particle and form at least one high molecular weight analyte ion, but is low enough to avoid fragmenting the high molecular weight analyte ion. The high molecular weight analyte ion is extracted out from the ion trap, and is then analyzed using a detector. The detector is preferably a pyrolyzing and ionizing detector.

Reilly, Peter T. A. (Knoxville, TN); Harris, William A. (Naperville, IL)

2010-03-02T23:59:59.000Z

367

Studies of Atmospheric Chemistry and Reaction Mechanisms Using Optical Spectroscopy and Mass Spectrometry  

E-Print Network (OSTI)

measurement system of peroxy radicals using a chemical amplification/laser-measurement system of peroxy radicals using a chemical amplification/laser-

Liu, Yingdi

2011-01-01T23:59:59.000Z

368

A Mass Spectrometry Study of Isotope Separation in the Laser Plume  

E-Print Network (OSTI)

as detailed in the Non-Proliferation Treaty (NPT), is toUnited Nations, “Treaty on the Non-Proliferation of Nuclear

Suen, Timothy Wu

2012-01-01T23:59:59.000Z

369

Characterization of the Molecular Composition of Secondary Organic Aerosols using High Resolution Mass Spectrometry  

E-Print Network (OSTI)

in secondary organic aerosol formation from isoprene, Proc.biogenic secondary organic aerosol, J. Phys. Chem. A, 112(in secondary organic aerosol, Environ. Sci. Technol. , 41(

Sellon, Rachel Elizabeth

2012-01-01T23:59:59.000Z

370

Anthropogenic particulate source characterization and source apportionment using aerosol time-of-flight mass spectrometry  

E-Print Network (OSTI)

vehicles, biomass burning, coal combustion, meat cooking,Arabia: biomass/biofuel burning and fossil fuel combustion,Arabia: biomass/biofuel burning and fossil fuel combustion,

Toner, Stephen Mark

2007-01-01T23:59:59.000Z

371

Extending the frontiers of mass spectrometric instrumentation and methods  

SciTech Connect

The focus of this dissertation is two-fold: developing novel analysis methods using mass spectrometry and the implementation and characterization of a novel ion mobility mass spectrometry instrumentation. The novel mass spectrometry combines ion trap for ion/ion reactions coupled to an ion mobility cell. The long term goal of this instrumentation is to use ion/ion reactions to probe the structure of gas phase biomolecule ions. The three ion source - ion trap - ion mobility - qTOF mass spectrometer (IT - IM - TOF MS) instrument is described. The analysis of the degradation products in coal (Chapter 2) and the imaging plant metabolites (Appendix III) fall under the methods development category. These projects use existing commercial instrumentation (JEOL AccuTOF MS and Thermo Finnigan LCQ IT, respectively) for the mass analysis of the degraded coal products and the plant metabolites, respectively. The coal degradation paper discusses the use of the DART ion source for fast and easy sample analysis. The sample preparation consisted of a simple 50 fold dilution of the soluble coal products in water and placing the liquid in front of the heated gas stream. This is the first time the DART ion source has been used for analysis of coal. Steven Raders under the guidance of John Verkade came up with the coal degradation projects. Raders performed the coal degradation reactions, worked up the products, and sent them to me. Gregg Schieffer developed the method and wrote the paper demonstrating the use of the DART ion source for the fast and easy sample analysis. The plant metabolite imaging project extends the use of colloidal graphite as a sample coating for atmospheric pressure LDI. DC Perdian and I closely worked together to make this project work. Perdian focused on building the LDI setup whereas Schieffer focused on the MSn analysis of the metabolites. Both Perdian and I took the data featured in the paper. Perdian was the primary writer of the paper and used it as a chapter in his dissertation. Perdian and Schieffer worked together to address the revisions and publish it in Rapid Communications in Mass Spectrometry Journal.

Schieffer, Gregg

2010-12-15T23:59:59.000Z

372

Accelerators, Beams And Physical Review Special Topics - Accelerators And Beams  

SciTech Connect

Accelerator science and technology have evolved as accelerators became larger and important to a broad range of science. Physical Review Special Topics - Accelerators and Beams was established to serve the accelerator community as a timely, widely circulated, international journal covering the full breadth of accelerators and beams. The history of the journal and the innovations associated with it are reviewed.

Siemann, R.H.; /SLAC

2011-10-24T23:59:59.000Z

373

NEUTRAL-BEAM INJECTION  

SciTech Connect

The emphasis in the preceding chapters has been on magnetic confinement of high temperature plasmas. The question of production and heating of such plasmas has been dealt with relatively more briefly. It should not be inferred, however, that these matters must therefore be either trivial or unimportant. A review of the history reveals that in the early days all these aspects of the controlled fusion problem were considered to be on a par, and were tackled simultaneously and with equal vigor. Only the confinement problem turned out to be much more complex than initially anticipated, and richer in challenge to the plasma physicist than the questions of plasma production and heating. On the other hand, the properties of high-temperature plasmas and plasma confinement can only be studied experimentally after the problems of production and of heating to adequate temperatures are solved. It is the purpose of this and the next chapter to supplement the preceding discussions with more detail on two important subjects: neutral-beam injection and radio-frequency heating. These are the major contenders for heating in present and future tokamak and mirror fusion experiments, and even in several proposed reactors. For neutral beams we emphasize here the technology involved, which has undergone a rather remarkable development. The physics of particle and energy deposition in the plasma, and the discussion of the resulting effects on the confined plasma, have been included in previous chapters, and some experimental results are quoted there. Other heating processes of relevance to fusion are mentioned elsewhere in this book, in connection with the experiments where they are used: i.e. ohmic heating, adiabatic compression heating, and alpha-particle heating in Chapter 3 by H.P. Furth; more ohmic heating in Chapter 7, and shock-implosion heating, laser heating, and relativistic-electron beam heating in Chapter 8, both by W. E. Quinn. These methods are relatively straightforward in their physics and their technology, or in any case they are considered to be adequately covered by these other authors.

Kunkel, W.B.

1980-06-01T23:59:59.000Z

374

Heavy Oil Upgrading from Electron Beam (E-Beam) Irradiation  

E-Print Network (OSTI)

Society's growing demands for energy results in rapid increase in oil consumption and motivates us to make unconventional resources conventional resources. There are enormous amounts of heavy oil reserves in the world but the lack of cost effective technologies either for extraction, transportation, or refinery upgrading hinders the development of heavy oil reserves. One of the critical problems with heavy oil and bitumen is that they require large amounts of thermal energy and expensive catalysts to upgrade. This thesis demonstrates that electron beam (E-Beam) heavy oil upgrading, which uses unique features of E-Beam irradiation, may be used to improve conventional heavy oil upgrading. E-Beam processing lowers the thermal energy requirements and could sharply reduce the investment in catalysts. The design of the facilities can be simpler and will contribute to lowering the costs of transporting and processing heavy oil and bitumen. E-Beam technology uses the high kinetic energy of fast electrons, which not only transfer their energy but also interact with hydrocarbons to break the heavy molecules with lower thermal energy. In this work, we conducted three major stages to evaluate the applicability of E-Beam for heavy oil upgrading. First, we conducted laboratory experiments to investigate the effects of E-Beam on hydrocarbons. To do so, we used a Van de Graff accelerator, which generates the high kinetic energy of electrons, and a laboratory scale apparatus to investigate extensively how radiation effects hydrocarbons. Second, we studied the energy transfer mechanism of E-Beam upgrading to optimize the process. Third, we conducted a preliminary economic analysis based on energy consumption and compared the economics of E-Beam upgrading with conventional upgrading. The results of our study are very encouraging. From the experiments we found that E-Beam effect on hydrocarbon is significant. We used less thermal energy for distillation of n-hexadecane (n-C16) and naphtha with E-Beam. The results of experiments with asphaltene indicate that E-Beam enhances the decomposition of heavy hydrocarbon molecules and improves the quality of upgraded hydrocarbon. From the study of energy transfer mechanism, we estimated heat loss, fluid movement, and radiation energy distribution during the reaction. The results of our economic evaluation show that E-Beam upgrading appears to be economically feasible in petroleum industry applications. These results indicate significant potential for the application of E-Beam technology throughout the petroleum industry, particularly near production facilities, transportation pipelines, and refining industry.

Yang, Daegil

2009-12-01T23:59:59.000Z

375

Tuning the beam: a physics perspective on beam diagnostic instrumentation  

SciTech Connect

In a nutshell, the role of a beam diagnostic measurement is to provide information needed to get a particle beam from Point A (injection point) to Point B (a target) in a useable condition, with 'useable' meaning the right energy and size and with acceptable losses. Specifications and performance requirements of diagnostics are based on the physics of the particle beam to be measured, with typical customers of beam parameter measurements being the accelerator operators and accelerator physicists. This tutorial will be a physics-oriented discussion of the interplay between tuning evolutions and the beam diagnostics systems that support the machine tune. This will include the differences between developing a tune and maintaining a tune, among other things. Practical longitudinal and transverse tuning issues and techniques from a variety of proton and electron machines will also be discussed.

Gulley, Mark S [Los Alamos National Laboratory

2010-01-01T23:59:59.000Z

376

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1, 2002 Nov. 18, 2002 Nov. 25, 2002 Dec. 02, 2002 1, 2002 Nov. 18, 2002 Nov. 25, 2002 Dec. 02, 2002 Dec. 09, 2002 Dec. 16, 2002 Dec. 23, 2002 Dec. 30, 2002 Jan. 06, 2003 Jan. 13, 2003 Jan. 20, 2003 Jan. 27, 2003 Feb. 03, 2003 Feb. 10, 2003 Feb. 17, 2003 Feb. 24, 2003 Mar. 03, 2003 Mar. 10, 2003 Mar. 17, 2003 Mar. 24, 2003 Mar. 31, 2003 Back to Table of Contents WEEK OF Nov. 11, 2002 Nov. 11, 2002 Nov. 12, 2002 Nov. 13, 2002 Nov. 14, 2002 Nov. 15, 2002 Nov. 16, 2002 Nov. 17, 2002 BEAM LINE 1-4 Nov. 11, 2002 Nov. 12, 2002 Nov. 13, 2002 Nov. 14, 2002 Nov. 15, 2002 Nov. 16, 2002 Nov. 17, 2002 Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled Unscheduled

377

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

Nov. 04, 2013 Nov. 11, 2013 Nov. 18, 2013 Nov. 25, 2013 Nov. 04, 2013 Nov. 11, 2013 Nov. 18, 2013 Nov. 25, 2013 Dec. 02, 2013 Dec. 09, 2013 Dec. 16, 2013 Dec. 23, 2013 Dec. 30, 2013 Jan. 06, 2014 Jan. 13, 2014 Jan. 20, 2014 Jan. 27, 2014 Feb. 03, 2014 Back to Table of Contents WEEK OF Nov. 04, 2013 Ops Re-start Nov. 04, 2013 Nov. 05, 2013 Nov. 06, 2013 Nov. 07, 2013 Nov. 08, 2013 Nov. 09, 2013 Nov. 10, 2013 BEAM LINE 1-4 Nov. 04, 2013 Nov. 05, 2013 Nov. 06, 2013 Nov. 07, 2013 Nov. 08, 2013 Nov. 09, 2013 Nov. 10, 2013 DOWN DOWN DOWN 8891 C.TASSONE 8891 C.TASSONE 8891 C.TASSONE 8891 C.TASSONE

378

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

5-4 5-4 Nov. 05, 2007 Nov. 06, 2007 Nov. 07, 2007 Nov. 08, 2007 Nov. 09, 2007 Nov. 10, 2007 Nov. 11, 2007 Unscheduled 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU CHANGE/8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU BEAM LINE 8-1 Nov. 05, 2007 Nov. 06, 2007 Nov. 07, 2007 Nov. 08, 2007 Nov. 09, 2007 Nov. 10, 2007 Nov. 11, 2007 8821 D.Brehmer 8821 D.Brehmer 8821 D.Brehmer 3064* S.SUN 3075 M.GARNER 3075 M.GARNER 3075 M.GARNER

379

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

4, 2013 Nov. 11, 2013 Nov. 18, 2013 Nov. 25, 2013 4, 2013 Nov. 11, 2013 Nov. 18, 2013 Nov. 25, 2013 Dec. 02, 2013 Dec. 09, 2013 Dec. 16, 2013 Dec. 23, 2013 Dec. 30, 2013 Jan. 06, 2014 Jan. 13, 2014 Jan. 20, 2014 Jan. 27, 2014 Feb. 03, 2014 Back to Table of Contents WEEK OF Nov. 04, 2013 Ops Re-start Nov. 04, 2013 Nov. 05, 2013 Nov. 06, 2013 Nov. 07, 2013 Nov. 08, 2013 Nov. 09, 2013 Nov. 10, 2013 BEAM LINE 5-4 Nov. 04, 2013 Nov. 05, 2013 Nov. 06, 2013 Nov. 07, 2013 Nov. 08, 2013 Nov. 09, 2013 Nov. 10, 2013 DOWN DOWN DOWN DOWN DOWN DOWN DOWN

380

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1-4 1-4 Nov. 28, 2005 Nov. 29, 2005 Nov. 30, 2005 Dec. 01, 2005 Dec. 02, 2005 Dec. 03, 2005 Dec. 04, 2005 MA 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE CHANGE/8840 J.POPL 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE 8840 J.POPLE BEAM LINE 2-1 Nov. 28, 2005 Nov. 29, 2005 Nov. 30, 2005 Dec. 01, 2005 Dec. 02, 2005 Dec. 03, 2005 Dec. 04, 2005 MA 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

5-4 5-4 Nov. 15, 2010 Nov. 16, 2010 Nov. 17, 2010 Nov. 18, 2010 Nov. 19, 2010 Nov. 20, 2010 Nov. 21, 2010 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU 8820 D.LU BEAM LINE 8-1 Nov. 15, 2010 Nov. 16, 2010 Nov. 17, 2010 Nov. 18, 2010 Nov. 19, 2010 Nov. 20, 2010 Nov. 21, 2010 Unscheduled Unscheduled Unscheduled 3269 S.SUN 3269 S.SUN 3269 S.SUN 3269 S.SUN

382

Pulsed electron beam precharger  

Science Conference Proceedings (OSTI)

Florida State University is investigating the concept of pulsed electron beams for fly ash precipitation. This report describes the results and data on three of the subtasks of this project and preliminary work only on the remaining five subtasks. Described are the modification of precharger for pulsed and DC energization of anode; installation of the Q/A measurement system; and modification and installation of pulsed power supply to provide both pulsed and DC energization of the anode. The other tasks include: measurement of the removal efficiency for monodisperse simulated fly ash particles; measurement of particle charge; optimization of pulse energization schedule for maximum removal efficiency; practical assessment of results; and measurement of the removal efficiency for polydisperse test particles. 15 figs., 1 tab. (CK)

Finney, W.C. (ed.); Shelton, W.N.

1990-01-01T23:59:59.000Z

383

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1-4 1-4 Nov. 05, 2007 Nov. 06, 2007 Nov. 07, 2007 Nov. 08, 2007 Nov. 09, 2007 Nov. 10, 2007 Nov. 11, 2007 Unscheduled Unscheduled 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY Unscheduled CHANGE/8051 M.TONE 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY Unscheduled 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY 8051 M.TONEY BEAM LINE 2-1 Nov. 05, 2007 Nov. 06, 2007 Nov. 07, 2007 Nov. 08, 2007 Nov. 09, 2007 Nov. 10, 2007 Nov. 11, 2007 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 8859 B.JOHNSON 3157* M.MONTERO-CA 3087 L.FUENTES-COB 3087 L.FUENTES-COB

384

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1-5 1-5 Nov. 28, 2005 Nov. 29, 2005 Nov. 30, 2005 Dec. 01, 2005 Dec. 02, 2005 Dec. 03, 2005 Dec. 04, 2005 MA 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ BEAM LINE 7-1 Nov. 28, 2005 Nov. 29, 2005 Nov. 30, 2005 Dec. 01, 2005 Dec. 02, 2005 Dec. 03, 2005 Dec. 04, 2005 MA DOWN DOWN DOWN DOWN DOWN DOWN

385

The System of Nanosecond 280-KeV He+ Pulsed Beam  

SciTech Connect

At Fast Neutron Research Facility, the 150 kV-pulses neutron generator is being upgraded to a 280-kV-pulsed-He beam for time-of-flight Rutherford backscattering spectrometry. It involves replacing the existing beam line elements by a multicusp ion source, a 400-kV accelerating tube, 45{sup o}-double focusing dipole magnet and quadrupole lens. The multicusp ion source is a compact filament-driven of 2.6 cm in diameter and 8 cm in length. The current extracted is 20.4 {micro}A with 13 kV of extraction voltage and 8.8 kV of Einzel lens voltage. The beam emittance has found to vary between 6-12 mm mrad. The beam transport system has to be redesigned based on the new elements. The important part of a good pulsed beam depends on the pulsing system. The two main parts are the chopper and buncher. An optimized geometry for the 280 keV pulsed helium ion beam will be presented and discussed. The PARMELA code has been used to optimize the space charge effect, resulting in pulse width of less than 2 ns at a target. The calculated distance from a buncher to the target is 4.6 m. Effects of energy spread and phase angle between chopper and buncher have been included in the optimization of the bunch length.

Junphong, P.; Ano, V.; Lekprasert, B.; Suwannakachorn, D.; Thongnopparat, N.; Vilaithong, T.; /Chiang Mai U.; Wiedemann, H.; /SLAC /SLAC, SSRL

2006-05-01T23:59:59.000Z

386

Ion-mobility Spectrometry Based NOx Sensor - Nuclear Engineering Division  

NLE Websites -- All DOE Office Websites (Extended Search)

NPNS > Sensors and NPNS > Sensors and Instrumentation and NDE > Energy System Application > DOE Office of Transportation Technologies > Ion-mobility Spectrometry Based NOx Sensor Capabilities Sensors and Instrumentation and Nondestructive Evaluation Overview Energy System Applications Overview DOE Office of Fossil Energy DOE Office of Transportation Technologies Ion-mobility Spectrometry Based NOx Sensor DOE Office of Power Technology Work for Others Safety-Related Applications Homeland Security Applications Biomedical Applications Millimiter Wave Group Papers Other NPNS Capabilities Work with Argonne Contact us For Employees Site Map Help Join us on Facebook Follow us on Twitter NE on Flickr Sensors and Instrumentation and Nondestructive Evaluation Ion-mobility Spectrometry Based NOx Sensor

387

Method of trivalent chromium concentration determination by atomic spectrometry  

DOE Patents (OSTI)

A method is disclosed for determining the concentration of trivalent chromium Cr(III) in a sample. The addition of perchloric acid has been found to increase the atomic chromium spectrometric signal due to Cr(III), while leaving the signal due to hexavalent chromium Cr(VI) unchanged. This enables determination of the Cr(III) concentration without pre-concentration or pre-separation from chromium of other valences. The Cr(III) concentration may be measured using atomic absorption spectrometry, atomic emission spectrometry or atomic fluorescence spectrometry.

Reheulishvili, Aleksandre N. (Tbilisi, 0183, GE); Tsibakhashvili, Neli Ya. (Tbilisi, 0101, GE)

2006-12-12T23:59:59.000Z

388

Mass Wasting in the Western Galapagos Islands  

E-Print Network (OSTI)

Oceanic island volcanoes such as those in the Hawaiian, Canary and Galapagos Islands are known to become unstable, causing failures of the subaerial and submarine slopes of the volcanic edifices. These mass wasting events appear to be the primary source of destruction and loss of volume of many oceanic islands, but our knowledge of mass wasting is still rudimentary in many seamount and island chains. To better understand mass wasting in the western Galapagos Islands, multi-beam bathymetry and backscatter sidescan sonar images were used to examine topography and acoustic backscatter signatures that are characteristic of mass wasting. Observations show that mass wasting plays an important role in the development of Galapagos volcanoes. While volcanic activity continues to conceal the submarine terrain, the data show that four forms of mass wasting are identified including debris flows, slumps sheets, chaotic slumps, and detached blocks. A total of 23 mass wasting features were found to exist in the western Galapagos Islands, including fourteen debris flows with one that incorporated a set of detached blocks, seven slump sheets, and one chaotic slump. Some of the indentified features have obvious origination zones while the sources of others are not clearly identifiable. Approximately 73 percent of the surveyed coastlines are affected by slumping on the steep upper slopes and ~64 percent are affected by debris flows on the lower slopes. Unlike the giant landslides documented by GLORIA imagery around the Hawaiian Islands, the western Galapagos Islands appear to be characterized by small slump sheets existing along the steep shallow submarine flanks of the island and by debris flows that are flanked by rift zones and extend off the platform. This study indicates that submarine mass wasting is widespread in the western Galapagos, suggesting that the production of small-scale downslope movement is part of the erosive nature of these oceanic volcanic islands.

Hall, Hillary

2011-08-01T23:59:59.000Z

389

IonBeamMicroFab  

NLE Websites -- All DOE Office Websites (Extended Search)

Ion Beam Manufacture of Microscale Ion Beam Manufacture of Microscale Tools and Components Manufacturing Technologies Sandia Manufacturing Science &Technology's Focused Ion Beam (FIB) laboratory provides an opportunity for research, development and prototyping. Currently, our scientists are devel- oping methods for ion beam sculpting microscale tools, components and devices. This includes shaping of specialty tools such as end-mills, turning tools and indenters. Many of these have been used in ultra-precision machining DOE applications. Additionally, staff are developing the capability to ion mill geo- metrically-complex features and substrates. This includes the ability to sputter predeter- mined curved shapes of various symmetries and periodicities. Capabilities and Expertise * Two custom-built focused ion beam sys-

390

Beam line windows at LAMPF  

Science Conference Proceedings (OSTI)

The A-6 main beam-line window at LAMPF separates the vacuum of the main beam line from the isotope production station, proton irradiation ports, and the beam stop, which operate in air. This window must withstand the design beam current of 1 mA at 800 MeV for periods of at least 3000 hours without failure. The window is water cooled and must be strong enough to withstand the 2.1 MPa (300 psig) cooling water pressure, as well as beam-induced thermal stresses. Two designs have been used to meet these goals, a stepped-plate window and a hemispherical window, both made from a precipitation-hardened nickel base alloy, Alloy 718. Calculations of the temperatures and stresses in each of these windows are presented.

Brown, R.D.; Grisham, D.L.; Lambert, J.E.

1985-01-01T23:59:59.000Z

391

Laser-beam-alignment system  

DOE Patents (OSTI)

A plurality of pivotal reflectors direct a high-power laser beam onto a workpiece, and a rotatable reflector is movable to a position wherein it intercepts the beam and deflects a major portion thereof away from its normal path, the remainder of the beam passing to the pivotal reflectors through an aperture in the rotating reflector. A plurality of targets are movable to positions intercepting the path of light traveling to the pivotal reflectors, and a preliminary adjustment of the latter is made by use of a low-power laser beam reflected from the rotating reflector, after which the same targets are used to make a final adjustment of the pivotal reflectors with the portion of the high-power laser beam passed through the rotating reflector. The system was developed to cut the casings of spent nuclear fuel elements into segments as the initial step in recovering usable fuel. (WHK)

Kasner, W.H.; Racki, D.J.; Swenson, C.E.

1982-02-26T23:59:59.000Z

392

Beamed Energy Propulsion: Research Status And Needs--Part 1  

SciTech Connect

One promising solution to the operationally responsive space is the application of remote electromagnetic energy to propel a launch vehicle into orbit. With beamed energy propulsion, one can leave the power source stationary on the ground or space, and direct heat propellant on the spacecraft with a beam from a fixed station. This permits the spacecraft to leave its power source at home, saving significant amounts of mass, greatly improving performance. This concept, which removes the mass penalty of carrying the propulsion energy source on board the vehicle, was first proposed by Arthur Kantrowitz in 1972; he invoked an extremely powerful ground based laser. The same year Michael Minovich suggested a conceptually similar 'in-space' laser rocket system utilizing a remote laser power station. In the late 1980's, Air Force Office of Scientific Research (AFOSR) funded continuous, double pulse laser and microwave propulsion while Strategic Defense Initiative Office (SDIO) funded ablative laser rocket propulsion. Currently AFOSR has been funding the concept initiated by Leik Myrabo, repetitively pulsed laser propulsion, which has been universally perceived, arguably, to be the closest for mid-term applications. This 2-part paper examines the investment strategies in beamed energy propulsion and technical challenges to be overcome. Part 1 presents a world-wide review of beamed energy propulsion research, including both laser and microwave arenas.

Birkan, Mitat [Air Force Office of Scientific Research, Arlington, Virginia, 22203 (United States)

2008-04-28T23:59:59.000Z

393

New aspects of beam-beam interactions in hadron colliders  

Science Conference Proceedings (OSTI)

Beam-beam phenomena have until now limited the beam currents and luminosity achievable in the Tevatron. injected proton currents are about ten times larger than the anti-proton currents so beam-beam effects have largely acted on the anti-protons and at all stages of the operational cycle. The effects of the anti-protons on the protons have until now been relatively benign but that may change at higher anti-proton currents. After 36 bunches of protons are injected and placed on the proton helix, anti-protons are injected four bunches at a time. After all bunches are injected, acceleration to top energy takes bout 85 seconds. After reaching flat top, the optics around the interaction regions (IRs) is changed to lower {beta}* from 1.6 m to 0.35 m at B0 and D0. The beams are brought into collision by collapsing the separation bumps around the IPs. During a high energy physics store each bunch experiences two head-on collisions with bunches in the opposing beam and seventy long-range interactions. At all other stages of the operational cycle, each bunch experiences only long-range interactions--seventy two in all. Performance limitations from beam-beam effects until now have been primarily due to these long-range interactions. The anti-proton losses at 150 GeV have decreased during the last year mostly due to better control of the orbits, tunes and chromaticities. During this period proton intensities have increased about 50%, thus anti-proton losses at 150 GeV have not been very dependent on proton intensities. Anti-proton and proton losses on the ramp together with proton losses at 150 GeV are the dominant contributors to the Tevatron inefficiency.

Tanaji Sen

2003-06-02T23:59:59.000Z

394

Chemical and Structural Features of Plants That Contribute to Biomass Recalcitrance  

E-Print Network (OSTI)

of the Pyrolysis of Biomass. 1. Fundamentals. Energy Fuelsof the Pyrolysis of Biomass. 1. Fundamentals. Energy Fuelsand Pyrolysis Molecular Beam Mass Spectrometry. Biomass

DeMartini, Jaclyn Diana

2011-01-01T23:59:59.000Z

395

New Combined Laser Ablation Platform Determines Cell Wall Chemistry...  

NLE Websites -- All DOE Office Websites (Extended Search)

ablation laser mass spectrometer molecular beam REMPI laser NREL has designed and developed a combined laser ablation pulsed sample introductionmass spectrometry platform that...

396

Amplitude and phase?modulation (AM?PM) wide?band photothermal spectrometry. II. Experiment  

Science Conference Proceedings (OSTI)

Amplitude and phase?modulation (AM?PM) wide?band photothermal spectrometry is experimentally demonstrated

J. F. Power

1990-01-01T23:59:59.000Z

397

Mass independent kinetic energy reducing inlet system for vacuum environment  

Science Conference Proceedings (OSTI)

A particle inlet system comprises a first chamber having a limiting orifice for an incoming gas stream and a micrometer controlled expansion slit. Lateral components of the momentum of the particles are substantially cancelled due to symmetry of the configuration once the laminar flow converges at the expansion slit. The particles and flow into a second chamber, which is maintained at a lower pressure than the first chamber, and then moves into a third chamber including multipole guides for electromagnetically confining the particle. The vertical momentum of the particles descending through the center of the third chamber is minimized as an upward stream of gases reduces the downward momentum of the particles. The translational kinetic energy of the particles is near-zero irrespective of the mass of the particles at an exit opening of the third chamber, which may be advantageously employed to provide enhanced mass resolution in mass spectrometry.

Reilly, Peter T. A. [Knoxville, TN

2010-12-14T23:59:59.000Z

398

Size, effect of flexible proof mass on the mechanical behavior of micron-scale cantilevers for energy harvesting appications.  

Science Conference Proceedings (OSTI)

Mechanical behavior of micron-scale cantilevers with a distributed, flexible proof mass is investigated to understand proof mass size effects on the performance of microelectromechanical system energy harvesters. Single-crystal silicon beams with proof masses of various lengths were fabricated using focused ion beam milling and tested using atomic force microscopy. Comparison of three different modeling results with measured data reveals that a 'two-beam' method has the most accurate predictive capability in terms of both resonant frequency and strain. Accurate strain prediction is essential because energy harvested scales with strain squared and maximum strain will be a design limit in fatigue.

Kim, M.; Hong, S.; Miller, D. J.; Dugundji, J.; Wardle, B. L. (Materials Science Division); (MIT)

2011-12-15T23:59:59.000Z

399

Laser beam alignment apparatus and method  

DOE Patents (OSTI)

The disclosure relates to an apparatus and method for laser beam alignment. Thermoelectric properties of a disc in a laser beam path are used to provide an indication of beam alignment and/or automatic laser alignment.

Gruhn, Charles R. (Martinez, CA); Hammond, Robert B. (Los Alamos, NM)

1981-01-01T23:59:59.000Z

400

Mass-Loaded Flows  

E-Print Network (OSTI)

A key process within astronomy is the exchange of mass, momentum, and energy between diffuse plasmas in many types of astronomical sources (including planetary nebulae, wind-blown bubbles, supernova remnants, starburst superwinds, and the intracluster medium) and dense, embedded clouds or clumps. This transfer affects the large scale flows of the diffuse plasmas as well as the evolution of the clumps. I review our current understanding of mass-injection processes, and examine intermediate-scale structure and the global effect of mass-loading on a flow. I then discuss mass-loading in a variety of diffuse sources.

J. M. Pittard

2006-07-13T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Does Information Have Mass?  

E-Print Network (OSTI)

Does information have mass? This question has been asked many times and there are many answers even on the Internet, including on Yahoo Answers. Usually the answer is "no". Attempts have been made to assess the physical mass of information by estimating the mass of electrons feeding the power-guzzling computers and devices making up the Internet, the result being around 50 gram. Other efforts to calculate the mass of information have assumed that each electron involved in signal transfer carries one bit of information, which makes the corresponding mass to be about 10^-5 gram. We address the fundamental question of minimum mass related to a bit of information from the angles of quantum physics and special relativity. Our results indicate that there are different answers depending on the physical situation, and sometimes the mass can even be negative. We tend to be skeptical about the earlier mass estimations, mentioned above, because our results indicate that the electron's mass does not play a role in any on...

Kish, Laszlo B

2013-01-01T23:59:59.000Z

402

LHCb Beam-Gas Imaging Results  

E-Print Network (OSTI)

The high resolution of the LHCb vertex detector makes it possible to perform precise measurements of vertices of beam-gas and beam-beam interactions and allows beam parameters such as positions, angles and widths to be determined. Using the directly measured beam properties the novel beam-gas imaging method is applied in LHCb for absolute luminosity determination. In this contribution we briefly describe the method and the preliminary results obtained with May 2010 data.

P. Hopchev

2011-07-07T23:59:59.000Z

403

OBSERVATION OF STRONG - STRONG AND OTHER BEAM - BEAM EFFECTS IN RHIC.  

SciTech Connect

RHIC is currently the only hadron collider in which strong-strong beam-beam effects can be seen. For the first time, coherent beam-beam modes were observed in a bunched beam hadron collider. Other beam-beam effects in RHIC were observed in operation and in dedicated experiments with gold ions, deuterons and protons. Observations include measurements of beam-beam induced tune shifts, lifetime and emittance growth measurements with and without beam-beam interaction, and background rates as a function of tunes. During ramps unequal radio frequencies in the two rings cause the crossing points to move longitudinally. Thus bunches experience beam-beam interactions only in intervals and the tunes are modulated. In this article we summarize the most important beam-beam observations made so far.

Fischer, W; Brennan, J M; Cameron, P; Connolly, R; Montag, C; Peggs, S; Pilat, F; Ptitsyn, V; Tepikian, S; Trbojevic, D

2003-05-12T23:59:59.000Z

404

Ion Beam Modification of Materials  

SciTech Connect

This volume contains the proceedings of the 14th International Conference on Ion Beam Modification of Materials, IBMM 2004, and is published by Elsevier-Science Publishers as a special issue of Nuclear Instruments and Methods B. The conference series is the major international forum to present and discuss recent research results and future directions in the field of ion beam modification, synthesis and characterization of materials. The first conference in the series was held in Budapest, Hungary, 1978, and subsequent conferences were held every two years at locations around the Globe, most recently in Japan, Brazil, and the Netherlands. The series brings together physicists, materials scientists, and ion beam specialists from all over the world. The official conference language is English. IBMM 2004 was held on September 5-10, 2004. The focus was on materials science involving both basic ion-solid interaction processes and property changes occurring either during or subsequent to ion bombardment and ion beam processing in relation to materials and device applications. Areas of research included Nanostructures, Multiscale Modeling, Patterning of Surfaces, Focused Ion Beams, Defects in Semiconductors, Insulators and Metals, Cluster Beams, Radiation Effects in Materials, Photonic Devices, Ion Implantation, Ion Beams in Biology and Medicine including New Materials, Imaging, and Treatment.

Averback, B; de la Rubia, T D; Felter, T E; Hamza, A V; Rehn, L E

2005-10-10T23:59:59.000Z

405

Intense low energy positron beams  

Science Conference Proceedings (OSTI)

Intense positron beams are under development or being considered at several laboratories. Already today a few accelerator based high intensity, low brightness e{sup +} beams exist producing of the order of 10{sup 8} {minus} 10{sup 9} e{sup +}/sec. Several laboratories are aiming at high intensity, high brightness e{sup +} beams with intensities greater than 10{sup 9} e{sup +}/sec and current densities of the order of 10{sup 13} {minus} 10{sup 14} e{sup +} sec{sup {minus}} {sup 1}cm{sup {minus}2}. Intense e{sup +} beams can be realized in two ways (or in a combination thereof) either through a development of more efficient B{sup +} moderators or by increasing the available activity of B{sup +} particles. In this review we shall mainly concentrate on the latter approach. In atomic physics the main trust for these developments is to be able to measure differential and high energy cross-sections in e{sup +} collisions with atoms and molecules. Within solid state physics high intensity, high brightness e{sup +} beams are in demand in areas such as the re-emission e{sup +} microscope, two dimensional angular correlation of annihilation radiation, low energy e{sup +} diffraction and other fields. Intense e{sup +} beams are also important for the development of positronium beams, as well as exotic experiments such as Bose condensation and Ps liquid studies.

Lynn, K.G.; Jacobsen, F.M.

1993-12-31T23:59:59.000Z

406

Results from STAR Beam Energy Scan Program  

E-Print Network (OSTI)

Results from the Beam Energy Scan (BES) program conducted recently by STAR experiment at RHIC are presented. The data from Phase-I of the BES program collected in Au+Au collisions at center-of-mass energies (\\sqrt{s_{NN}}) of 7.7, 11.5, 19.6, 27, and 39 GeV cover a wide range of baryon chemical potential ?\\mu_B (100-400 MeV) in the QCD phase diagram. Several STAR results from the BES Phase-I related to "turn-o?ff" of strongly inter- acting quark-gluon plasma (sQGP) signatures and signals of QCD phase boundary are reported. In addition to this, an outlook is presented for the future BES Phase-II program and a possible ?fixed target program at STAR.

Michal Sumbera

2013-01-30T23:59:59.000Z

407

PURIFICATION OF IRIDIUM BY ELECTRON BEAM MELTING  

Science Conference Proceedings (OSTI)

The purification of iridium metal by electron beam melting has been characterized for 48 impurity elements. Chemical analysis was performed by glow discharge mass spectrographic (GDMS) analysis for all elements except carbon, which was analyzed by combustion. The average levels of individual elemental impurities in the starting powder varied from 37 g/g to 0.02 g/g. The impurity elements Li, Na, Mg, P, S, Cl, K, Ca, Mn, Co, Ni, Cu, Zn, As, Pd, Ag, Cd, Sn, Sb, Te, Ba, Ce, Tl, Pb, and Bi were not detectable following the purification. No significant change in concentration of the elements Ti, V, Zr, Nb, Mo, and Re was found. The elements B, C, Al, Si, Cr, Fe, Ru, Rh, and Pt were partially removed by vaporization during electron beam melting. Langmuir's equation for ideal vaporization into a vacuum was used to calculate for each impurity element the expected ratio of impurity content after melting to that before melting. Equilibrium vapor pressures were calculated using Henry's law, with activity coefficients obtained from published data for the elements Fe, Ti, and Pt. Activity coefficients were estimated from enthalpy data for Al, Si, V, Cr, Mn, Co, Ni, Zr, Nb, Mo, and Hf and an ideal solution model was used for the remaining elements. The melt temperature was determined from measured iridium weight loss. Excellent agreement was found between measured and calculated impurity ratios for all impurity elements. The results are consistent with some localized heating of the melt pool due to rastering of the electron beam, with an average vaporization temperature of 3100 K as compared to a temperature of 2965 K calculated for uniform heating of the melt pool. The results are also consistent with ideal mixing in the melt pool.

Ohriner, Evan Keith [ORNL

2008-01-01T23:59:59.000Z

408

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

Feb. 14, 2005 Feb. 21, 2005 Feb. 28, 2005 Mar. 07, 2005 Feb. 14, 2005 Feb. 21, 2005 Feb. 28, 2005 Mar. 07, 2005 Mar. 14, 2005 Mar. 21, 2005 Mar. 28, 2005 Apr. 04, 2005 Apr. 11, 2005 Apr. 18, 2005 Apr. 25, 2005 May 02, 2005 May 09, 2005 May 16, 2005 May 23, 2005 May 30, 2005 Jun. 06, 2005 Jun. 13, 2005 Jun. 20, 2005 Jun. 27, 2005 Jul. 04, 2005 Jul. 11, 2005 Jul. 18, 2005 Jul. 25, 2005 Aug. 01, 2005 Back to Table of Contents WEEK OF Feb. 14, 2005 Feb. 14, 2005 Feb. 15, 2005 Feb. 16, 2005 Feb. 17, 2005 Feb. 18, 2005 Feb. 19, 2005 Feb. 20, 2005 BEAM LINE 1-5 Feb. 14, 2005 Feb. 15, 2005 Feb. 16, 2005 Feb. 17, 2005 Feb. 18, 2005 Feb. 19, 2005 Feb. 20, 2005 8858 D.HARRINGTON 8858 D.HARRIN/DOWN 8858 D.HARRINGTON 8858 D.HARRINGTON 8858 D.HARRINGTON 8858 D.HARRINGTON 8858 D.HARRINGTON

409

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

1, 2013 Nov. 18, 2013 Nov. 25, 2013 Dec. 02, 2013 1, 2013 Nov. 18, 2013 Nov. 25, 2013 Dec. 02, 2013 Dec. 09, 2013 Dec. 16, 2013 Dec. 23, 2013 Dec. 30, 2013 Jan. 06, 2014 Jan. 13, 2014 Jan. 20, 2014 Jan. 27, 2014 Feb. 03, 2014 Feb. 10, 2014 Feb. 17, 2014 Feb. 24, 2014 Back to Table of Contents WEEK OF Nov. 11, 2013 Nov. 11, 2013 Nov. 12, 2013 Nov. 13, 2013 Nov. 14, 2013 Nov. 15, 2013 Nov. 16, 2013 Nov. 17, 2013 BEAM LINE 7-1 Nov. 11, 2013 Nov. 12, 2013 Nov. 13, 2013 Nov. 14, 2013 Nov. 15, 2013 Nov. 16, 2013 Nov. 17, 2013 8803 C.Smith 8803 C.Smith 8803 C.Smith 8803 C.Smith 8803 C.Smith 4B02 A.Yeh 8050 C.Smith 8803 C.Smith 8803 C.Smith 8803 C.Smith 8803 C.Smith Unscheduled MC CHECKOUT/8050 8050 C.Smith

410

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

7-1 7-1 Oct. 26, 2009 Oct. 27, 2009 Oct. 28, 2009 Oct. 29, 2009 Oct. 30, 2009 Oct. 31, 2009 Nov. 01, 2009 CHANGE/8803* C.SMI 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH 8803* C.SMITH BEAM LINE 9-1 Oct. 26, 2009 Oct. 27, 2009 Oct. 28, 2009 Oct. 29, 2009 Oct. 30, 2009 Oct. 31, 2009 Nov. 01, 2009 CHANGE/8861* I.MAT 8861* I.MATHEWS 8861* I.MATHEWS 8861* I.MATHEWS 8861* I.MATHEWS 8861* I.MATHEWS 8861* I.MATHEWS

411

SSRL BEAM PORT SCHEDULE  

NLE Websites -- All DOE Office Websites (Extended Search)

7-1 7-1 Nov. 15, 2010 Nov. 16, 2010 Nov. 17, 2010 Nov. 18, 2010 Nov. 19, 2010 Nov. 20, 2010 Nov. 21, 2010 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 2B87 I.SEVRIOUKOVA 2B87 I.SEVRIOUKOVA 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ MC CHECKOUT/2B87 2B87 I.SEVRIOUKOVA 2B87 I.SEVRIOUKOVA 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 8845 A.GONZALEZ 2B87 I.SEVRIOUKOVA 2B87 I.SEVRIOUKOVA 2B87 I.SEVRIOUKOVA BEAM LINE 9-1 Nov. 15, 2010 Nov. 16, 2010 Nov. 17, 2010 Nov. 18, 2010 Nov. 19, 2010 Nov. 20, 2010 Nov. 21, 2010 8866 T.DOUKOV 8866 T.DOUKOV 8866 T.DOUKOV 8866 T.DOUKOV 8866 T.DOUKOV FACI FACI

412

Probing Organic Transistors with Infrared Beams  

NLE Websites -- All DOE Office Websites (Extended Search)

Probing Organic Transistors with Probing Organic Transistors with Infrared Beams Probing Organic Transistors with Infrared Beams Print Wednesday, 26 July 2006 00:00 Silicon-based transistors are well-understood, basic components of contemporary electronic technology. In contrast, there is growing need for the development of electronic devices based on organic polymer materials. Organic field-effect transistors (FETs) are ideal for special applications that require large areas, light weight, and structural flexibility. They also have the advantage of being easy to mass-produce at very low cost. However, even though this class of devices is finding a growing number of applications, electronic processes in organic materials are still not well understood. A group of researchers from the University of California and the ALS has succeeded in probing the intrinsic electronic properties of the charge carriers in organic FETs using infrared spectromicroscopy. The results of their study could help in the future development of sensors, large-area displays, and other plastic electronic components.

413

Electron beam machining using rotating and shaped beam power distribution  

DOE Patents (OSTI)

An apparatus and method for electron beam (EB) machining (drilling, cutting and welding) that uses conventional EB guns, power supplies, and welding machine technology without the need for fast bias pulsing technology. The invention involves a magnetic lensing (EB optics) system and electronic controls to: 1) concurrently bend, focus, shape, scan, and rotate the beam to protect the EB gun and to create a desired effective power-density distribution, and 2) rotate or scan this shaped beam in a controlled way. The shaped beam power-density distribution can be measured using a tomographic imaging system. For example, the EB apparatus of this invention has the ability to drill holes in metal having a diameter up to 1000 .mu.m (1 mm or larger), compared to the 250 .mu.m diameter of laser drilling.

Elmer, John W. (Pleasanton, CA); O' Brien, Dennis W. (Livermore, CA)

1996-01-01T23:59:59.000Z

414

NIST SURF: Beamline 10: Electron beam imaging  

Science Conference Proceedings (OSTI)

Beamline 10: Electron beam imaging. Description: ... In its unperturbed state, the vertical electron beam size is quite small, in the order of a few 10 µm. ...

2012-11-19T23:59:59.000Z

415

PowerBeam Inc | Open Energy Information  

Open Energy Info (EERE)

PowerBeam, Inc. Place Sunnyvale, California Zip CA 94085 Product PowerBeam holds the patent to a power transmission technology that produces wireless electricity. Coordinates...

416

Compact Alignment for Diagnostic Laser Beams  

Physicist and optical engineer Mike Rushford developed the laser beam . centering and pointing system. The laser beam . centering and pointing system

417

Beam-powered lunar rover design  

Science Conference Proceedings (OSTI)

Manned exploration of our nearest neighbors in the solar systems is the primary goal of the Space Exploration Initiative (SEI). An integral part of any manned lunar or planetary outpost will be a system for manned excursions over the surface of the planet. This report presents a preliminary design for a lunar rover capable of supporting four astronauts on long-duration excursions across the lunar landscape. The distinguishing feature of this rover design is that power is provided to rover via a laser beam from an independent orbiting power satellite. This system design provides very high power availability with minimal mass on the rover vehicle. With this abundance of power, and with a relatively small power-system mass contained in the rover, the vehicle can perform an impressive suite of mission-related activity. The rover might be used as the first outpost for the lunar surface (i.e., a mobile base). A mobile base has the advantage of providing extensive mission activities without the expense of establishing a fixed base. This concept has been referred to as ``Rove First.`` A manned over, powered through a laser beam, has been designed for travel on the lunar surface for round-trip distances in the range of 1000 km, although the actual distance traveled is not crucial since the propulsion system does not rely on energy storage. The life support system can support a 4-person crew for up to 30 days, and ample power is available for mission-related activities. The 8000-kg rover has 30 kW of continuous power available via a laser transmitter located at the Earth-moon L1 libration point, about 50,000 km above the surface of the moon. This rover, which is designed to operate in either day or night conditions, has the flexibility to perform a variety of power-intensive missions. 24 refs.

Dagle, J.E.; Coomes, E.P.; Antoniak, Z.I.; Bamberger, J.A.; Bates, J.M.; Chiu, M.A.; Dodge, R.E.; Wise, J.A.

1992-03-01T23:59:59.000Z

418

Beam-powered lunar rover design  

Science Conference Proceedings (OSTI)

Manned exploration of our nearest neighbors in the solar systems is the primary goal of the Space Exploration Initiative (SEI). An integral part of any manned lunar or planetary outpost will be a system for manned excursions over the surface of the planet. This report presents a preliminary design for a lunar rover capable of supporting four astronauts on long-duration excursions across the lunar landscape. The distinguishing feature of this rover design is that power is provided to rover via a laser beam from an independent orbiting power satellite. This system design provides very high power availability with minimal mass on the rover vehicle. With this abundance of power, and with a relatively small power-system mass contained in the rover, the vehicle can perform an impressive suite of mission-related activity. The rover might be used as the first outpost for the lunar surface (i.e., a mobile base). A mobile base has the advantage of providing extensive mission activities without the expense of establishing a fixed base. This concept has been referred to as Rove First.'' A manned over, powered through a laser beam, has been designed for travel on the lunar surface for round-trip distances in the range of 1000 km, although the actual distance traveled is not crucial since the propulsion system does not rely on energy storage. The life support system can support a 4-person crew for up to 30 days, and ample power is available for mission-related activities. The 8000-kg rover has 30 kW of continuous power available via a laser transmitter located at the Earth-moon L1 libration point, about 50,000 km above the surface of the moon. This rover, which is designed to operate in either day or night conditions, has the flexibility to perform a variety of power-intensive missions. 24 refs.

Dagle, J.E.; Coomes, E.P.; Antoniak, Z.I.; Bamberger, J.A.; Bates, J.M.; Chiu, M.A.; Dodge, R.E.; Wise, J.A.

1992-03-01T23:59:59.000Z

419

A high transmission analyzing magnet for intense high charge state beams  

DOE Green Energy (OSTI)

The low energy beam transport (LEBT) for VENUS will provide for extraction, mass analysis and transport to the axial injection line for the 88-Inch Cyclotron. The new LEBT was designed from the beginning to handle high intensity beams where space charge forces strongly affect the transmission. The magnet has a unique design with specially shaped poles to apply sextupole correction in both the horizontal and vertical plane.

Leitner, M.; Abbott, S.R.; Leitner, D.; Lyneis, C.

2002-06-11T23:59:59.000Z

420

On the Photon Mass  

E-Print Network (OSTI)

We review the case for the photon having a tiny mass compatible with the experimental limits. We go over some possible experimental tests for such a photon mass including the violation of Lorentz symmetry. We point out that such violations may already have been witnessed in tests involving high energy gamma rays from outer space as also ultra high energy cosmic rays.

Burra G. Sidharth

2007-06-22T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Thermal masses in leptogenesis  

E-Print Network (OSTI)

We investigate the validity of using thermal masses in the kinematics of final states in the decay rate of heavy neutrinos in leptogenesis calculations. We find that using thermal masses this way is a reasonable approximation, but corrections arise through quantum statistical distribution functions and leptonic quasiparticles.

Kiessig, Clemens P

2009-01-01T23:59:59.000Z

422

The origin of mass  

Science Conference Proceedings (OSTI)

The origin of mass is one of the deepest mysteries in science. Neutrons and protons, which account for almost all visible mass in the Universe, emerged from a primordial plasma through a cataclysmic phase transition microseconds after the Big Bang. However, ... Keywords: Gordon Bell Prize categories: scalability and time to solution, SC13 proceedings

Peter Boyle, Michael I. Buchoff, Norman Christ, Taku Izubuchi, Chulwoo Jung, Thomas C. Luu, Robert Mawhinney, Chris Schroeder, Ron Soltz, Pavlos Vranas, Joseph Wasem

2013-11-01T23:59:59.000Z

423

Elbow mass flow meter  

DOE Patents (OSTI)

The present invention includes a combination of an elbow pressure drop generator and a shunt-type mass flow sensor for providing an output which gives the mass flow rate of a gas that is nearly independent of the density of the gas. For air, the output is also approximately independent of humidity. 3 figs.

McFarland, A.R.; Rodgers, J.C.; Ortiz, C.A.; Nelson, D.C.

1994-08-16T23:59:59.000Z

424

Circular, confined distribution for charged particle beams  

DOE Patents (OSTI)

A charged particle beam line is formed with magnetic optics that manipulate the charged particle beam to form the beam having a generally rectangular configuration to a circular beam cross-section having a uniform particle distribution at a predetermined location. First magnetic optics form a charged particle beam to a generally uniform particle distribution over a square planar area at a known first location. Second magnetic optics receive the charged particle beam with the generally square configuration and affect the charged particle beam to output the charged particle beam with a phase-space distribution effective to fold corner portions of the beam toward the core region of the beam. The beam forms a circular configuration having a generally uniform spatial particle distribution over a target area at a predetermined second location. 26 figs.

Garnett, R.W.; Dobelbower, M.C.

1995-11-21T23:59:59.000Z

425

Circular, confined distribution for charged particle beams  

DOE Patents (OSTI)

A charged particle beam line is formed with magnetic optics that manipulate the charged particle beam to form the beam having a generally rectangular configuration to a circular beam cross-section having a uniform particle distribution at a predetermined location. First magnetic optics form a charged particle beam to a generally uniform particle distribution over a square planar area at a known first location. Second magnetic optics receive the charged particle beam with the generally square configuration and affect the charged particle beam to output the charged particle beam with a phase-space distribution effective to fold corner portions of the beam toward the core region of the beam. The beam forms a circular configuration having a generally uniform spatial particle distribution over a target area at a predetermined second location.

Garnett, Robert W. (Los Alamos, NM); Dobelbower, M. Christian (Toledo, OH)

1995-01-01T23:59:59.000Z

426

W Transverse Mass  

NLE Websites -- All DOE Office Websites (Extended Search)

Some Data Analysis Some Data Analysis The Tevatron produces millions of collisions each second in CDF and DZero. The detectors have hardware triggers to decide if a collision is "interesting," that is it contains a candidate event for any one of a number studies. Our dataset contains 48,844 candidate events for a W mass study. There are other datasets to study Z mass, top and b quarks, QCD, etc. Why don't all the W decays give exactly the same mass? Are all these candidates really Ws? What if we chose only some of these data. How would our choice effect the value of the transverse mass? Work with your classmates. Test the data to see what you can learn. Help with data analysis. Record the best estimate of the W transverse mass from your data analysis. Explain which data you used and why. Check with your classmates and explain any differences between your estimate and theirs.

427

Particle beam fusion  

SciTech Connect

Today, in keeping with Sandia Laboratories` designation by the Department of Energy as the lead laboratory for the pulsed power approach to fusion, its efforts include major research activities and the construction of new facilities at its Albuquerque site. Additionally, in its capacity as lead laboratory, Sandia coordinates DOE-supported pulsed power fusion work at other government operated laboratories, with industrial contractors, and universities. The beginning of Sandia`s involvement in developing fusion power was an outgrowth of its contributions to the nation`s nuclear weapon program. The Laboratories` work in the early 1960`s emphasized the use of pulsed radiation environments to test the resistance of US nuclear weapons to enemy nuclear bursts. A careful study of options for fusion power indicated that Sandia`s expertise in the pulsed power field could provide a powerful match to ignite fusion fuel. Although creating test environments is an achieved goal of Sandia`s overall program, this work and other military tasks protected by appropriate security regulations will continue, making full use of the same pulsed power technology and accelerators as the fusion-for-energy program. Major goals of Sandia`s fusion program including the following: (1) complete a particle accelerator to deliver sufficient beam energy for igniting fusion targets; (2) obtain net energy gain, this goal would provide fusion energy output in excess of energy stored in the accelerator; (3) develop a technology base for the repetitive ignition of pellets in a power reactor. After accomplishing these goals, the technology will be introduced to the nation`s commercial sector.

1980-12-31T23:59:59.000Z

428

Repetitively pumped electron beam device  

DOE Patents (OSTI)

Disclosed is an apparatus for producing fast, repetitive pulses of controllable length of an electron beam by phased energy storage in a transmission line of length matched to the number of pulses and specific pulse lengths desired. 12 figs.

Schlitt, L.G.

1979-07-24T23:59:59.000Z

429

Repetitively pumped electron beam device  

DOE Patents (OSTI)

Apparatus for producing fast, repetitive pulses of controllable length of an electron beam by phased energy storage in a transmission line of length matched to the number of pulses and specific pulse lengths desired.

Schlitt, Leland G. (Livermore, CA)

1979-01-01T23:59:59.000Z

430

The Fermilab neutrino beam program  

Science Conference Proceedings (OSTI)

This talk presents an overview of the Fermilab Neutrino Beam Program. Results from completed experiments as well as the status and outlook for current experiments is given. Emphasis is given to current activities towards planning for a future program.

Rameika, Regina A.; /Fermilab

2007-01-01T23:59:59.000Z

431

INSTABILITIES OF RELATIVISTIC PARTICLE BEAMS  

E-Print Network (OSTI)

1965). K. W. Robinson, in SLAC Storage Ring Stumner Study,Beams, a Summary. Report, SLAC-49, L. J. Laslett, V. K.La.slett and A. M. Sessler, in SLAC-49, Sept. 1965 (see Ref.

Sessler, Andrew M.

2008-01-01T23:59:59.000Z

432

Center for Beam Physics, 1992  

Science Conference Proceedings (OSTI)

This report contains the following information on the center for beam physics: Facilities; Organizational Chart; Roster; Profiles of Staff; Affiliates; Center Publications (1991--1993); and 1992 Summary of Activities.

Not Available

1993-06-01T23:59:59.000Z

433

MassMass transfer andtransfer and arationstearationste  

E-Print Network (OSTI)

, temperature, T, and energy, E, are scalars and their gradient is a vector dc/dx or arationste scalars diffusion coefficient D; for species A in medium B : D = DAB 4 erföringo dx dc D dt.A dm m Massöve c cSepa dx dc )DD(m th Irreversible Thermodynamics considers Thermo-diffusion 4 erföringo T T Thermo

Zevenhoven, Ron

434

Confined energy distribution for charged particle beams  

SciTech Connect

A charged particle beam is formed to a relatively larger area beam which is well-contained and has a beam area which relatively uniformly deposits energy over a beam target. Linear optics receive an accelerator beam and output a first beam with a first waist defined by a relatively small size in a first dimension normal to a second dimension. Nonlinear optics, such as an octupole magnet, are located about the first waist and output a second beam having a phase-space distribution which folds the beam edges along the second dimension toward the beam core to develop a well-contained beam and a relatively uniform particle intensity across the beam core. The beam may then be expanded along the second dimension to form the uniform ribbon beam at a selected distance from the nonlinear optics. Alternately, the beam may be passed through a second set of nonlinear optics to fold the beam edges in the first dimension. The beam may then be uniformly expanded along the first and second dimensions to form a well-contained, two-dimensional beam for illuminating a two-dimensional target with a relatively uniform energy deposition.

Jason, Andrew J. (Los Alamos, NM); Blind, Barbara (Los Alamos, NM)

1990-01-01T23:59:59.000Z

435

Beam cooling: Principles and achievements  

SciTech Connect

After a discussion of Liouville's theorem, and its implications for beam cooling, a brief description is given of each of the various methods of beam cooling: stochastic, electron, radiation, laser, ionization, etc. For each, we present the type of particle for which it is appropriate, its range of applicability, and the currently achieved degree of cooling. For each method we also discuss the present applications and, also, possible future developments and further applications.

Mohl, Dieter; Sessler, Andrew M.

2003-05-18T23:59:59.000Z

436

Direct e-beam lithography of PDMS  

Science Conference Proceedings (OSTI)

In this paper, the viability of directly exposing thin films of liquid poly(dimethylsiloxane) (PDMS) to electron beam (e-beam) irradiation using e-beam lithographic methods for the purpose of creating permanent micro-scale components has been investigated. ... Keywords: Lithography, PDMS, Poly(dimethylsiloxane), e-Beam

J. Bowen; D. Cheneler; A. P. G. Robinson

2012-09-01T23:59:59.000Z

437

BEAM SCRUBBING FOR RHIC POLARIZED PROTON RUN.  

SciTech Connect

One of the intensity limiting factor of RHIC polarized proton beam is the electron cloud induced pressure rise. A beam scrubbing study shows that with a reasonable period of time of running high intensity 112-bunch proton beam, the pressure rise can be reduced, allowing higher beam intensity.

ZHANG,S.Y.FISCHER,W.HUANG,H.ROSER,T.

2004-07-05T23:59:59.000Z

438

Higgs Mass Calculations  

NLE Websites -- All DOE Office Websites (Extended Search)

this sheet now. Help with data analysis Higgs Mass Plot Project Contact: Thomas Jordan - jordant@fnal.gov Web Maintainer: qnet-webmaster@fnal.gov Last Update: August 22,...

439

Isotopic Effect on Ion Mobility and Separation of Isotopomers by High-Field Ion Mobility Spectrometry  

SciTech Connect

Since early 1900-s, when vacuum techniques and ion detectors first enabled investigations of gas-phase ions, two approaches to their separation and characterization have emerged - mass spectrometry (MS) and ion mobility spectrometry (IMS).1,2 Though both exploit that distinct charged species move in electric fields differently, MS is performed in vacuum and is based only on the ion mass/charge (m/q) ratio while IMS involves sufficiently dense buffer gases and relies on ion transport properties. The first major discovery enabled by MS was the existence of isotopes by Thomson and Aston,3 and isotopic analyses have since been integral to MS. In particular, the preparative separation of U isotopes using Lawrence’s Calutron was the first industrial application of MS,4 and isotopic labeling is key to MS quantification methods. With IMS, the issue of isotopes was largely ignored as the resolving power (R) was generally too low for their separation. Here, we demonstrate that recently developed high-resolution differential IMS can separate isotopic molecular ions, including nominal isobars with different isotopic content and isotopomers. This capability may enable a new method for isotope separation in a small-scale format at ambient pressure and aid localization of labeled sites in various molecules. Perhaps most importantly, the isotopic shifts depend on the labeled atom position and thus may contain the kind of detailed structural information that is available in solution or solid state using tools such as NMR but has not generally been obtainable for gas-phase ions.

Shvartsburg, Alexandre A.; Clemmer, David E.; Smith, Richard D.

2010-10-01T23:59:59.000Z

440

Solids mass flow determination  

DOE Patents (OSTI)

Method and apparatus for determining the mass flow rate of solids mixed with a transport fluid to form a flowing mixture. A temperature differential is established between the solids and fluid. The temperature of the transport fluid prior to mixing, the temperature of the solids prior to mixing, and the equilibrium temperature of the mixture are monitored and correlated in a heat balance with the heat capacities of the solids and fluid to determine the solids mass flow rate.

Macko, Joseph E. (Hempfield Township, Westmoreland County, PA)

1981-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "beam mass spectrometry" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

INTRA - BEAM SCATTERING MEASUREMENTS IN RHIC.  

DOE Green Energy (OSTI)

RHIC in gold operation shows significant intra-beam scattering due to the high charge state of the stored ions. Intra-beam scattering leads to longitudinal and transverse emittance growth. The longitudinal emittance growth causes debunching in operation; the transverse emittance growth contributes to the reduction of the beam and luminosity lifetimes. The longitudinal and transverse beam growth was measured. Beam growth measurement are compared with computations.

FISCHER,W.; CONNOLLY,R.; TEPIKIAN,S.; VAN ZEIJTS,J.; ZENO,K.

2002-06-02T23:59:59.000Z

442

Long Baseline Neutrino Beams and Large Detectors  

SciTech Connect

It is amazing to acknowledge that in roughly 70 years from when the existence of the neutrino was postulated, we are now contemplating investigating the mysteries of this particle (or particles) requiring and utilizing detectors of 300 ktons , distances of 1,000-2,000 kilometers, beam intensities of megawatts and underground depth of 5,000 feet. This evolution has evolved slowly, from the experimental discovery of the neutrino in 1956, to the demonstration that there were two neutrinos in 1962 and three and only three by 1991. The great excitement occurred in the 2000's coming from the study of solar and atmospheric neutrinos in which neutrinos were observed to oscillate and therefore have mass. Although the absolute mass of any of the neutrinos has yet to be determined (the upper limit is less than I electron volt) the difference in this square of these masses has been measured, yielding a value of (2.3 {+-} .2) 10{sup -3} ev{sup 2} for atmospheric neutrinos and (7.6 {+-} .2) 10{sup -5} ev{sup 2} for solar neutrinos. In addition their mixing angles were found to be 45{sup o} for atmospheric neutrinos and 34{sup o} for solar neutrinos. This present state of knowledge on neutrinos is pictorially displayed in Fig. 1. Of course, mixing between flavors had already been observed in the quark sector as exemplified by the Cabbibo-Kobayashi-Meskawa Matrix. It was therefore natural to extend this formalism to the lepton sector involving unitary 3 x 3 matrices and one CP violating phase. This is shown in Fig. 2 for the two sectors, quark and leptons including the Jarlskog invariant (J).

Samios,N.P.

2008-10-27T23:59:59.000Z

443

W Transverse Mass  

NLE Websites -- All DOE Office Websites (Extended Search)

Transverse Mass Histogram Transverse Mass Histogram Data for 49,844 candidate W events are in an Excel spreadsheet with the following data as shown in the table below: A B C D 1 Run No Event No W TMass GeV/c2 Bins 2 55237 19588 68.71732 3 55237 30799 72.19464 Get the data. Sort the data by ascending mass. Be sure to sort all the data in the first three columns! Make a histogram of the data. Rather than graphing the data as individual points, physicists group the data by mass. They consider the full range of the data and divide it into "bins" of equal range size. A histogram is a graph of the number of events in each bin vs. the bin range. They are looking for a peak in the data where most of the masses fall. This will be the value of the mass as detemined by that dataset, and the width of the distribution is a reflection of the errors in the measurements.

444

Machine and Beam Delivery Updates  

NLE Websites -- All DOE Office Websites (Extended Search)

MAchine and Beam delivery Updates FY13 MAchine and Beam delivery Updates FY13 Summary of Beam Delivery: FACET Summary Feb_15_22.pdf FACET Summary Feb_15_22.pdf FACET Summary Feb_23_Mar_1.pdf FACET Summary Feb_23_Mar_1.pdf FACET Summary Mar_2_8.pdf FACET Summary Mar_2_8.pdf FACET Summary Mar_9_15.pdf FACET Summary Mar_9_15.pdf FACET Summary Mar_16_22.pdf FACET Summary Mar_16_22.pdf FACET Summary Mar_23_29.pdf FACET Summary Mar_23_29.pdf FACET Summary Mar_30_Apr_5.pdf FACET Summary Mar_30_Apr_5.pdf FACET Summary Apr_6_12.pdf FACET Summary Apr_6_12.pdf FACET Summary Apr_27_May_3.pdf FACET Summary Apr_27_May_3.pdf FACET Summary May_4_10.pdf FACET Summary May_4_10.pdf Emittance Stability in Sector 2_31513.pdf Emittance Stability in Sector 2_31513.pdf FACET beam operations readiness with R56.pdf FACET beam operations readiness with R56.pdf (6/19/2013)

445

Beamed Energy Propulsion: Research Status And Needs--Part 2  

SciTech Connect

One promising solution to the operationally responsive space is the application of remote electromagnetic energy to propel a launch vehicle into orbit. With beamed energy propulsion, one can leave the power source stationary on the ground or space, and direct heat propellant on the spacecraft with a beam from a fixed station. This permits the spacecraft to leave its power source at home, saving significant amounts of mass, greatly improving performance. This concept, which removes the mass penalty of carrying the propulsion energy source on board the vehicle, was first proposed by Arthur Kantrowitz in 1972; he invoked an extremely powerful ground based laser. The same year Michael Minovich suggested a conceptually similar 'in-space' laser rocket system utilizing a remote laser power station. In the late 1980's, Air Force Office of Scientific Research (AFOSR) funded continuous, double pulse laser and microwave propulsion while Strategic Defense Initiative Office (SDIO) funded ablative laser rocket propulsion. Currently AFOSR has been funding the concept initiated by Leik Myrabo, repetitively pulsed laser propulsion, which has been universally perceived, arguably, to be the closest for mid-term applications. This 2-part paper examines the investment strategies in beamed energy propulsion and technical challenges to be covers Part 2 covers the present research status and needs.

Birkan, Mitat [Air Force Office of Scientific Research, Arlington, Virginia, 22203 (United States)

2008-04-28T23:59:59.000Z

446

Deposition of hetero-epitaxial In{sub 2}O{sub 3} thin films by molecular beam epitaxy  

SciTech Connect

Highly oriented thin film In{sub 2}O{sub 3} was heteroepitaxially grown on optically polished (100) plane of single crystalline yttria stabilized zirconia (YSZ) substrate using Molecular Beam Epitaxy (MBE). Full-width at half-maximum (FWHM) of X-ray rocking-curve showed 0.08{degree} for In{sub 2}O{sub 3} 200 nm thick layers indicating that excellent uniformity orientation compared with the heteroepitaxially-grown In{sub 2}O{sub 3} epitaxially deposited by the conventional methods such as electron-beam (e-beam) evaporation or sputtering method. The minimum yield ({chi}{sub min}) of the MBE grown in In{sub 2}O{sub 3} film of Rutherford Backscattering Spectrometry (RBS) was also extremely small value 3.1%, implying the very high crystallinity.

Taga, N.; Maekawa, M. [Asahi Glass Co., Ltd., Yokohama (Japan). Research Center; Shigesato, Y.; Yasui, I. [Univ. of Tokyo (Japan). Inst. of Industrial Science; Haynes, T.E. [Oak Ridge National Lab., TN (United States). Solid State Div.

1996-05-01T23:59:59.000Z

447

AFRD - Center for Beam Physics  

NLE Websites -- All DOE Office Websites (Extended Search)

Center for Beam Physics Center for Beam Physics Home Organization Outreach and Diversity Highlights Safety Links Intramural Group photo of our staff CBP staff, May 2011 CBP in the News: Read about an innovation in super-precise timing and synchronization; and a look toward the next generation of electron guns with responsiveness and brightness needed by future free-electron lasers such as those in the Next Generation Light Source initiative. Who We Are and What We Do The Center for Beam Physics (CBP) is a resource for meeting the challenges of accelerator science, and a source of many innovative concepts, within the Accelerator and Fusion Research Division. We have core expertise in accelerator physics and theory, accelerator modeling using high performance computing, and instrumentation,

448

BEAM DIFFUSION MEASUREMENTS AT RHIC.  

Science Conference Proceedings (OSTI)

During a store, particles from the beam core continually diffuse outwards into the halo through a variety of mechanisms. Understanding the diffusion rate as a function of particle amplitude can help discover which processes are important to halo growth. A collimator can be used to measure the amplitude growth rate as a function of the particle amplitude. In this paper we present results of diffusion measurements performed at the Relativistic Heavy Ion Collider (RHIC) with fully stripped gold ions, deuterons, and protons. We compare these results with measurements from previous years, and simulations, and discuss any factors that relate to beam growth in RHIC.

FLILLER,R.P.,IIIDREES,A.GASSNER,D.MCINTYRE,G.PEGGS,S.TRBOJEVIC,D.

2003-05-12T23:59:59.000Z

449

FEL options for power beaming  

DOE Green Energy (OSTI)

The demand for the output power of communication satellites has been increasing exponentially. The satellite power is generated from solar panels which collect the sunlight and convert it to electrical power. The power per satellite is limited due to the limit in the practical size of the solar panel. One way to meet the power demand is to employ multiple satellites (up to 10) per the internationally agreed-upon ``slot`` in the geosynchronous earth orbit (GEO). However, this approach is very expensive due to the high cost of sending a satellite into a GEO orbit. An alternative approach is power beaming, i.e., to illuminate the solar panels with high power, highly-directed laser beams from earth. The power beaming generates more power per satellite for the same area of the solar panel. The minimum optical beam power, interesting for power beaming application, is P{sub L} = 200kW. The wavelength is chosen to be {lambda} = 0.84 {micro}m, so that it is within one of the transmission windows of the air, and at the same time near the peak of the photo-voltaic conversion efficiency of Si, which is the commonly used material for the solar panels. Free electron lasers (FELs) are well suited for the power beaming application because they can provide high power with coherent wavefront, but without high energy density in media. In this article the authors discuss some principal issues, such as the choice of accelerator and electron gun, the choice of beam parameters, radiation hazards, technological availability, and overall efficiency and reliability of the installation. They also attempt to highlight the compromise between the cost of the primary installation, the operation cost, and the choice of technology, and its maturity. They then present several schemes for the accelerator-FEL systems based on RF accelerators. The initial electron beam accelerator up to the energy of a few MeV is more or less common for all these schemes.

Kim, K.J.; Zholents, A.A.; Zolotorev, M.S. [Lawrence Berkeley National Lab., CA (United States); Vinokurov, N.A. [Budker Inst. of Nuclear Physics, Novosibirsk (Russian Federation)

1997-10-01T23:59:59.000Z

450

Shimmed electron beam welding process  

DOE Patents (OSTI)

A modified electron beam welding process effects welding of joints between superalloy materials by inserting a weldable shim in the joint and heating the superalloy materials with an electron beam. The process insures a full penetration of joints with a consistent percentage of filler material and thereby improves fatigue life of the joint by three to four times as compared with the prior art. The process also allows variable shim thickness and joint fit-up gaps to provide increased flexibility for manufacturing when joining complex airfoil structures and the like.

Feng, Ganjiang (Clifton Park, NY); Nowak, Daniel Anthony (Alplaus, NY); Murphy, John Thomas (Niskayuna, NY)

2002-01-01T23:59:59.000Z

451

Thermal decomposition of CH{sub 3}CHO studied by matrix infrared spectroscopy and photoionization mass spectroscopy  

Science Conference Proceedings (OSTI)

A heated SiC microtubular reactor has been used to decompose acetaldehyde and its isotopomers (CH{sub 3}CDO, CD{sub 3}CHO, and CD{sub 3}CDO). The pyrolysis experiments are carried out by passing a dilute mixture of acetaldehyde (roughly 0.1%-1%) entrained in a stream of a buffer gas (either He or Ar) through a heated SiC reactor that is 2-3 cm long and 1 mm in diameter. Typical pressures in the reactor are 50-200 Torr with the SiC tube wall temperature in the range 1200-1900 K. Characteristic residence times in the reactor are 50-200 {mu}s after which the gas mixture emerges as a skimmed molecular beam at a pressure of approximately 10 {mu}Torr. The reactor has been modified so that both pulsed and continuous modes can be studied, and results from both flow regimes are presented. Using various detection methods (Fourier transform infrared spectroscopy and both fixed wavelength and tunable synchrotron radiation photoionization mass spectrometry), a number of products formed at early pyrolysis times (roughly 100-200 {mu}s) are identified: H, H{sub 2}, CH{sub 3}, CO, CH{sub 2}=CHOH, HC{identical_to}CH, H{sub 2}O, and CH{sub 2}=C=O; trace quantities of other species are also observed in some of the experiments. Pyrolysis of rare isotopomers of acetaldehyde produces characteristic isotopic signatures in the reaction products, which offers insight into reaction mechanisms that occur in the reactor. In particular, while the principal unimolecular processes appear to be radical decomposition CH{sub 3}CHO (+M) {yields} CH{sub 3}+ H + CO and isomerization of acetaldehyde to vinyl alc