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Sample records for batavia il 60510-0500

  1. Fermilab Cultural Events in Chicago's Far West Side

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    General Information Fermilab Arts & Lecture Series Kirk Road & Pine Street, P.O. Box 500, MS 111, Batavia, IL 60510 - 0500 Phone: Voice - 630.840.ARTS(2787), Fax - 630.840.5501 E-Mail: audweb@fnal.gov Tickets are sold on a first-come, first-served basis. Tickets may be charged on MasterCard, Visa, or Discover or paid for by check. Mail Order. Send a check (payable to Fermilab) or charge authorization with a self-addressed, stamped envelope to Fermilab Arts Series, P.O. Box 500, MS111,

  2. Fermilab Cultural Events in Batavia, IL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    True Blues with Corey Harris & Eric Bibb An evening of music & stories that chronicle the history of the Blues. Saturday, January 30 @ 8 pm Now in the Art Gallery - Harmonics -...

  3. IL

    Office of Legacy Management (LM)

    :; / 2. ' b-:-"y .",...4 * .-.a 2 IL !< :. 34 --' -, ' ' < I ,-. g Tvo"l r . . .-i- :- " .1-. . . . . NC0 /L ' J,, ' ;.' , -_I( + ? CENTRAL FILES c -&' { ' c;$y ;;j*' E ,J): ' i' Z, 1; p -^ r-raL-r.nuzT".Fn., , ,..-y - -' -ie .". iJ.&:~e!ct.;;' sf ' ;;i_is ,trip ' JG,' go f-Jj;~ey~ 2123 -:s<j .-&;.z ;y1y rrc&ed recr!p!~-,da.a .b ,&.j.,& .:*3;.. F-Y ' __ ,,,.x+; PC l;ealti: :.2,.i CCI ;et y. tirlr.&g t;1c oy-er at ion c.f sei;a~xl

  4. Microsoft Word - LBNF-DUNE Final 2015-09-29.docx

    Office of Environmental Management (EM)

    LBNFDUNE would make use of an existing high-energy particle ... a permit from the U.S. Army Corps of Engineers (USAGE). ... Batavia Public Library 10 S. Batavia Avenue Batavia, IL ...

  5. AIR M A IL

    Office of Legacy Management (LM)

    MEMORlAL DRIVE AIR M A IL . AtFxb.-zf .7.-i- M r. s. .II. Gown - Gentlemen: Re: A.E.C. Contract No. We assume the weight of the 9-l2" biscuits will:be 107'poutids ...

  6. IL FS Ecosmart Ltd | Open Energy Information

    Open Energy Info (EERE)

    Services Product: IL&FS Ecosmart Ltd., a subsidiary of the Infrastructure Leasing & Financial Services (IL&FS) Group, provides environmental services. References: IL&FS...

  7. Recent results from the Tevatron (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring Org: ... DETECTION; PARTICLE RAPIDITY; PHOSPHORS; QUANTUM CHROMODYNAMICS; STANDARD MODEL; ...

  8. Top quark properties from the Tevatron (Conference) | SciTech...

    Office of Scientific and Technical Information (OSTI)

    Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring Org: ... FERMILAB TEVATRON; LUMINOSITY; PHYSICS; QUANTUM CHROMODYNAMICS; SENSITIVITY; STANDARD ...

  9. IL Wted States Government

    Office of Legacy Management (LM)

    Tis&: p/WI-3 . IL Wted States Government ' 1, -1. \ k. 4 4L La. -iF 1 I ' __, 7, Department of Energy memorandum <jj ' 5 - ; +- ,I 12 ~ DATE: OCT 08 1992 REPLY TO AlTN OF: EM-421 (W. A. Williams, 903-8149) rn. I \ SUBJECT: Authorization for Remedial Action at the Former C. H. Schnoor & Company Site, Springdale, Pennsylvania TO: Manager, DOE Oak Ridge Field Office This is to notify you that the former C. H. Schnoor & Company facility in Springdale, Pennsylvania, is designated for

  10. US ENC IL Site Consumption

    U.S. Energy Information Administration (EIA) Indexed Site

    IL Site Consumption million Btu $0 $500 $1,000 $1,500 $2,000 $2,500 US ENC IL Expenditures dollars ALL ENERGY average per household (excl. transportation) 0 2,000 4,000 6,000 8,000 10,000 12,000 US ENC IL Site Consumption kilowatthours $0 $250 $500 $750 $1,000 $1,250 $1,500 US ENC IL Expenditures dollars ELECTRICITY ONLY average per household * Illinois households use 129 million Btu of energy per home, 44% more than the U.S. average. * High consumption, combined with low costs for heating fuels

  11. Category:Chicago, IL | Open Energy Information

    Open Energy Info (EERE)

    74 KB SVHospital Chicago IL Commonwealth Edison Co.png SVHospital Chicago IL ... 68 KB SVLargeHotel Chicago IL Commonwealth Edison Co.png SVLargeHotel Chicago I... 75 KB...

  12. Category:Springfield, IL | Open Energy Information

    Open Energy Info (EERE)

    Springfield IL Commonwealth Edison Co.png SVQuickServiceRestaura... 75 KB SVFullServiceRestaurant Springfield IL Commonwealth Edison Co.png...

  13. Fermilab | Science | Questions for the Universe | The Particle...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL VERITAS, Fred Lawrence Whipple Observatory, Amado, Arizona Xenon 10, Gran Sasso, Italy COUPP, Fermilab, Batavia, IL ZEPLIN II Cryogenic Dark Matter Search GLAST International ...

  14. DOE - Office of Legacy Management -- Chicago North IL Site - IL 05

    Office of Legacy Management (LM)

    North IL Site - IL 05 FUSRAP Considered Sites Chicago North, IL Alternate Name(s): National Guard Armory 124th Field Artillery Armory Illinois National Guard Armory Site IL.05-4 IL.05-5 Location: 5200 Cottage Grove Avenue, Chicago, Illinois IL.05-4 Historical Operations: Processed and stored uranium metal, resulting in uranium metal and dry uranium oxide contamination. Metallurgical operations were conducted by the University of Chicago, an MED contractor. IL.05-5 IL.05-7 IL.05-8 Eligibility

  15. Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex

    SciTech Connect (OSTI)

    Kennedy, M.K.; Park, L.S.

    1996-05-01

    IL-15 interacts with a heterotrimeric receptor that consists of the {beta} and {gamma} subunits of the IL-2 receptor (IL-2R) as well as a specific, high-affinity IL-15-binding subunit, which is designated IL-15R{alpha}. Since both the {beta} and the {gamma} subunits of the IL-2R are required for signaling by either IL-2 or IL-15, it is not surprising that these cytokines share many activities in vitro. However, the differential expression of these cytokines and the {alpha} chains of their receptors within various tissues and cell types suggests that IL-2 and IL-15 may perform at least partially distinct physiological functions. The production of IL-15 by macrophages, and possibly other cell types, in response to environmental stimuli and infectious agents suggests that IL-15 may play a role in protective immune responses, allograft rejection, and the pathogenesis of autoimmune diseases. 56 refs.

  16. IL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs Advanced Nuclear Energy Nuclear

  17. Il.-'",.'

    Office of Legacy Management (LM)

    ... D&D STATUS REPORT NEW BRUNSWICK LABORATORY NEW JERSEY SITE R. A. Wynveen V. R. Veluri W. H. Smith M. J. Robinet H. J. Moe DECEMBER 1981 INDEX Text D&D ......

  18. Structural and Biophysical Studies of the Human IL-7/IL-7R[alpha] Complex

    SciTech Connect (OSTI)

    McElroy, Craig A.; Dohm, Julie A.; Walsh, Scott T.R.; (OSU); (UPENN)

    2009-03-06

    IL-7 and IL-7R{alpha} bind the {gamma}{sub c} receptor, forming a complex crucial to several signaling cascades leading to the development and homeostasis of T and B cells. We report that the IL-7R{alpha} ectodomain uses glycosylation to modulate its binding constants to IL-7, unlike the other receptors in the {gamma}{sub c} family. IL-7 binds glycosylated IL-7R{alpha} 300-fold more tightly than unglycosylated IL-7R{alpha}, and the enhanced affinity is attributed primarily to an accelerated on rate. Structural comparison of IL-7 in complex to both forms of IL-7R{alpha} reveals that glycosylation does not participate directly in the binding interface. The SCID mutations of IL-7R{alpha} locate outside the binding interface with IL-7, suggesting that the expressed mutations cause protein folding defects in IL-7R{alpha}. The IL-7/IL-7R{alpha} structures provide a window into the molecular recognition events of the IL-7 signaling cascade and provide sites to target for designing new therapeutics to treat IL-7-related diseases.

  19. DOE - Office of Legacy Management -- Granite City IL Site - IL 28

    Office of Legacy Management (LM)

    Granite City IL Site - IL 28 FUSRAP Considered Sites Granite City, IL Alternate Name(s): Granite City Steel General Steel Industries General Steel Casings Corporation New Betatron Building IL.28-3 Location: 1417 State Street, Granite City, Illinois IL.28-3 Historical Operations: Under subcontract with Mallinckrodt and using a government-owned Betatron (magnetic induction electron accelerator), x-rayed natural uranium ingots and dingots to detect metallurgical flaws. Contamination from rubbing

  20. DOE - Office of Legacy Management -- Fansteel Metallurgical Corp - IL 16

    Office of Legacy Management (LM)

    Fansteel Metallurgical Corp - IL 16 FUSRAP Considered Sites Site: Fansteel Metallurgical Corp. (IL.16 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Chicago , Illinois IL.16-1 Evaluation Year: 1987 IL.16-3 Site Operations: Sole producer and supplier of tantalum and columbium metals to the MED. IL.16-1 IL.16-3 Site Disposition: Eliminated - No radioactive materials handled at this site IL.16-2 IL.16-3 Radioactive Materials

  1. The Sloan Digital Sky Survey Quasar Lens Search. IV. Statistical...

    Office of Scientific and Technical Information (OSTI)

    Article Resource Relation: Journal Name: Submitted to Astron.J.; Journal Volume: 140; Journal Issue: 2 Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL...

  2. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    National Accelerator Lab FNAL Batavia IL United States PARTICLE ACCELERATORS BEAM OPTICS CHANNELING ATTENUATION BEAM EXTRACTION BENDING CRYSTALS MESON BEAMS BEAMS PARTICLE...

  3. Carrigan, Jr., Richard A. [Fermi National Accelerator Lab. (FNAL...

    Office of Scientific and Technical Information (OSTI)

    Accelerator Lab. (FNAL), Batavia, IL (United States) 43 PARTICLE ACCELERATORS; BEAM OPTICS; CHANNELING; ATTENUATION; BEAM EXTRACTION; BENDING; CRYSTALS; MESON BEAMS; BEAMS;...

  4. Evidence for single top quark production at D0 (Conference) ...

    Office of Scientific and Technical Information (OSTI)

    de Moriond on Electroweak Interactions and Unified Theories, La Thuile, Italy, 10-17 Mar 2007 Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring...

  5. WIMPs at the galactic center (Journal Article) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Fermi National Accelerator Laboratory, Batavia, IL (United States) CERN, Geneva (Switzerland) Publication Date: 2015-05-01 OSTI Identifier: 1200688 Report Number(s):...

  6. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    (FNAL), Batavia, IL (United States) Fernald Area Office (United States) Fernald Environmental Management Project, OH (United States) FluxNet General Atomics Site, San...

  7. Fermilab | Science | Questions for the Universe | The Birth of...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tevatron, Fermilab, Batavia, IL Large Hadron Collider, CERN, Geneva, Switzerland BaBar, SLAC, Menlo Park, CA Further reading courtesy of Symmetry magazine Explain it in 60 Seconds: ...

  8. Fermilab | Science | Questions for the Universe | The Birth of...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Large Hadron Collider, CERN, Geneva, Switzerland Lattice Computational Facilities, Fermilab, Batavia, IL Further reading courtesy of Symmetry magazine The Growth of Inflation ...

  9. Global search for new physics at CDF (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring Org: ... PARTICLES AND FIELDS; FERMILAB COLLIDER DETECTOR; PHYSICS; SUPERSYMMETRY Experiment-HEP

  10. Rapid Cycling Synchrotron Option for Project X (Conference) ...

    Office of Scientific and Technical Information (OSTI)

    Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring Org: USDOE Country of Publication: United States Language: English Subject: 71 CLASSICAL AND QUANTUM ...

  11. Observation of a Higgs-like Boson in CMS at the LHC (Conference...

    Office of Scientific and Technical Information (OSTI)

    Batavia, IL Sponsoring Org: DOE Office of Science Country of Publication: United States Language: English Subject: 72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS Experiment-HEP...

  12. Beam Loss Control for the Fermilab Main Injector (Conference...

    Office of Scientific and Technical Information (OSTI)

    Laboratory (FNAL), Batavia, IL Sponsoring Org: DOE Office of Science Country of Publication: United States Language: English Subject: 43 PARTICLE ACCELERATORS Accelerators...

  13. Host galaxy spectra and consequences for supernova typing from...

    Office of Scientific and Technical Information (OSTI)

    ... Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510 (United States) Institut de Fsica d'Altes Energies, Universitat Autnoma de Barcelona, E-08193 ...

  14. Massachusetts Institute of Technology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Technology Short baseline neutrino workshop, Fermilab, Batavia, IL, May 13, 2011 Test of Lorentz and CPT violation with neutrinos Outline 1. Why Lorentz violation is...

  15. DOE - Office of Legacy Management -- Vapofier Corp - IL 25

    Office of Legacy Management (LM)

    Alternate Name: Therm-A-Shield Co. IL.25-1 Location: 11957 Vincennes Avenue , Blue Island , Illinois IL.25-2 Evaluation Year: 1990 IL.25-1 Site Operations: Vapofier...

  16. Environmental Survey preliminary report, Fermi National Accelerator Laboratory, Batavia, Illinois

    SciTech Connect (OSTI)

    Not Available

    1988-10-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the US Department of Energy (DOE) Fermi National Accelerator Laboratory (Fermilab), conducted September 14 through 25, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual participants for the Survey team are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Fermilab. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations performed at Fermilab, and interviews with site personnel. 110 refs., 26 figs., 41 tabs.

  17. Two decades of prairie restoration at Fermilab, Batavia, Illinois

    SciTech Connect (OSTI)

    Betz, R.F.; Lootens, R.J.; Becker, M.K.

    1996-12-31

    Successional Restoration is the method being used to restore the prairie at Fermilab on the former agricultural fields. This involves an initial planting, using aggressive species that have wide ecological tolerances which will grow well on abandoned agricultural fields. Collectively, these species are designated as the prairie matrix. The species used for this prairie matrix compete with and eventually eliminate most weedy species. They also provide an adequate fuel load capable of sustaining a fire within a few years after a site has been initially planted. Associated changes in the biological and physical structure of the soil help prepare the way for the successful introduction of plants of the later successional species. Only after the species of the prairie matrix are well established, is the species diversity increased by introducing species with narrower ecological tolerances. These species are thus characteristic of the later successional stages.

  18. EA-1075: Proposed Casey's Pond Improvement Project, Batavia, Illinois

    Broader source: Energy.gov [DOE]

    This EA evaluates the environmental impacts of a proposed system upgrade to meet improved operational criteria on the current Industrial Cooling Water distribution system used in the fixed target...

  19. IL.06-123 057 I I

    Office of Legacy Management (LM)

    IL.06-123 057 I I 7 Bechtel National. Inc Systems Engmeers - Constructors Jackson Plaza Tower e 800 Oak Ridge Turnpike Oak Ridge. Tennessee 37830 AII.il Addr.u P.O 80.350. 0.' R,dg_. 7N 3713' .0350 7.'-. 3785873 NOV 1 5 . . u.s. Department of Energy Oak Ridge Operations Post Office Box E Oak Ridge, Tennessee 37831 Attention: Peter J. Gross, Director Technical Services Division Subject: Bechtel Job No. 14501, FUSRAP Project DOE Contract No. DE-AC05-810R20722 Revised Letter Characterization Report

  20. Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling

    SciTech Connect (OSTI)

    Forward, Nicholas A.; Conrad, David M.; Power Coombs, Melanie R.; Doucette, Carolyn D.; Furlong, Suzanne J.; Lin, Tong-Jun; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia ; Hoskin, David W.

    2011-04-22

    Highlights: {yields} Curcumin inhibits CD4{sup +} T-lymphocyte proliferation. {yields} Curcumin inhibits interleukin-2 (IL-2) synthesis and CD25 expression by CD4{sup +} T-lymphocytes. {yields} Curcumin interferes with IL-2 receptor signaling by inhibiting JAK3 and STAT5 phosphorylation. {yields} IL-2-dependent regulatory T-lymphocyte function and Foxp3 expression is downregulated by curcumin. -- Abstract: Curcumin (diferulomethane) is the principal curcuminoid in the spice tumeric and a potent inhibitor of activation-induced T-lymphocyte proliferation; however, the molecular basis of this immunosuppressive effect has not been well studied. Here we show that micromolar concentrations of curcumin inhibited DNA synthesis by mouse CD4{sup +} T-lymphocytes, as well as interleukin-2 (IL-2) and CD25 ({alpha} chain of the high affinity IL-2 receptor) expression in response to antibody-mediated cross-linking of CD3 and CD28. Curcumin acted downstream of protein kinase C activation and intracellular Ca{sup 2+} release to inhibit I{kappa}B phosphorylation, which is required for nuclear translocation of the transcription factor NF{kappa}B. In addition, IL-2-dependent DNA synthesis by mouse CTLL-2 cells, but not constitutive CD25 expression, was impaired in the presence of curcumin, which demonstrated an inhibitory effect on IL-2 receptor (IL-2R) signaling. IL-2-induced phosphorylation of STAT5A and JAK3, but not JAK1, was diminished in the presence of curcumin, indicating inhibition of critical proximal events in IL-2R signaling. In line with the inhibitory action of curcumin on IL-2R signaling, pretreatment of CD4{sup +}CD25{sup +} regulatory T-cells with curcumin downregulated suppressor function, as well as forkhead box p3 (Foxp3) expression. We conclude that curcumin inhibits IL-2 signaling by reducing available IL-2 and high affinity IL-2R, as well as interfering with IL-2R signaling.

  1. DOE - Office of Legacy Management -- Heavy Minerals Inc - IL 14

    Office of Legacy Management (LM)

    Heavy Minerals Inc - IL 14 FUSRAP Considered Sites Site: Heavy Minerals, Inc. ( IL.14 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: W.R. Grace Company IL.14-1 Location: 836 South Michigan Avenue , Chicago , Illinois IL.14-2 Evaluation Year: 1990 IL.14-1 Site Operations: Submitted a proposal to supply thorium hydroxide to the AEC; no indication that the bid was accepted. IL.14-2 Site Disposition: Eliminated - No indication of work done with

  2. DOE - Office of Legacy Management -- Podbeilniac Corp - IL 22

    Office of Legacy Management (LM)

    Chicago, Illinois, on February 14, 1957; February 25, 1957 IL.22-2 - DOE Memorandum; Williams to File; Elimination of the Sites from the FUSRAP; August 29, 1994 IL.22-3 -...

  3. DOE - Office of Legacy Management -- Rock Island Arsenal - IL...

    Office of Legacy Management (LM)

    IL.09-1 - US AEC Letter; H. Donnelly to F. Pittman; Subject: Contaminated Ex-AEC-Owned or Leased Facilities; November 28, 1973 IL.09-2 - DOE Letter to DoD; J. Fiore to C. Shafer; ...

  4. DOE - Office of Legacy Management -- Morse Chemical Co - IL 0...

    Office of Legacy Management (LM)

    Morse Chemical Co - IL 0-05 FUSRAP Considered Sites Site: MORSE CHEMICAL CO. (IL.0-05 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: ...

  5. DOE - Office of Legacy Management -- Blockson Chemical Co - IL...

    Office of Legacy Management (LM)

    Blockson Chemical Co - IL 07 FUSRAP Considered Sites Site: Blockson Chemical Co. (IL.07) Eliminated from consideration under FUSRAP - Referred to US EPA Region V and the State of ...

  6. Il Woong Jung | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Il Woong Jung Assistant Scientist Education Ph.D., Electrical Engineering, Stanford University Research Summary Research interests are in photonic applications for micro- and nano-mechanical devices. Current research focuses on the manipulation of light-matter interaction at the nanoscale, specifically using micro- and nano-mechanical devices to control the optical properties of photonic nanostructures. The aim is to integrate optical nanostructures and nanomechanical devices to create novel

  7. DOE - Office of Legacy Management -- Chicago South IL Site -...

    Office of Legacy Management (LM)

    Alternate Name(s): University of Chicago Charles Herbert Jones Chemical Laboratory Ryerson Physical Laboratory Eckhart Hall Kent Chemical Laboratory Ricketts Laboratory IL.06-3 ...

  8. DOE - Office of Legacy Management -- Kaiser Aluminum Corp - IL...

    Office of Legacy Management (LM)

    Operations: Performed limited duration work extruding uranium billets into three CP-5 fuel elements, circa 1959. IL.19-2 Site Disposition: Eliminated - Potential for ...

  9. Intrathymic radioresistant stem cells follow an IL-2/IL-2R pathway during thymic regeneration after sublethal irradiation

    SciTech Connect (OSTI)

    Zuniga-Pfluecker, J.C.K.; Kruisbeek, A.M. )

    1990-05-15

    Sublethally irradiated mice undergo thymic regeneration which follows a phenotypic pattern of events similar to that observed during normal fetal development. Thymic regeneration after irradiation is the product of a limited pool of intrathymic radioresistant stem cells undergoing simultaneous differentiation. We show that in this model of T cell development, thymic regeneration follows a pathway in which the IL-2R is transiently expressed on CD4-/CD8- cells. IL-2R expression occurred during the exponential growth period of thymic regeneration, and IL-2R blocking prevented this explosive growth. Flow cytometry analysis revealed that the IL-2R blockade affected primarily the development of the immature CD3-/CD4-/CD8- (triple negative) cells and their ability to generate CD3+/CD4+/CD8+ or CD3+/CD4+/CD8- and CD3+/CD4-/CD8+ thymocytes. Thus, our findings demonstrate that blocking of the IL-2R resulted in an arrest in proliferation and differentiation by intrathymic radioresistant stem cells, indicating that the IL-2/IL-2R pathway is necessary for the expansion of immature triple negative T cells.

  10. DOE - Office of Legacy Management -- Madison - IL 26

    Office of Legacy Management (LM)

    Alternate Name(s): Spectrulite Consortium, Inc. Former Dow Chemical Company Site IL.26-3 ... for Remedial Action at the Former Dow Chemical Company Site in Madison, Illinois; ...

  11. Secretary Bodman Highlights Advanced Energy Initiative in Peoria, IL

    Broader source: Energy.gov [DOE]

    PEORIA, IL - Secretary of Energy Samuel W. Bodman today highlighted the goals of President Bush's Advanced Energy Initiative after consulting on an energy savings assessment at Caterpillar Inc.'s...

  12. DOE - Office of Legacy Management -- Crane Co - IL 13

    Office of Legacy Management (LM)

    17, 1995 IL.13-4 - Supplement to the DOE MemorandumChecklist; D. Levine to File; Subject: Description of Cranes involvement with MED related activities; February 11, 1987....

  13. Origin State>> CA ID ID IL IL KY NM NM NV NY OH TN TN TN, WA,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL IL KY NM NM NV NY OH TN TN TN, WA, CA TN TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Energx Argonne National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Sandia National Laboratory Los Alamos National Laboratory National Security Technologies West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant

  14. Interleukin-2 (IL-2) dependent expression of biologically relevant IL-2 receptors: uncoupling of anti-T3 induced receptor expression with cyclosporin

    SciTech Connect (OSTI)

    Gitter, A.B.D.; Labus, J.M.; Butler, L.D.

    1986-03-01

    Human peripheral blood T cell expression of IL-2 receptors (IL-2R), detected by both immunocytofluorometry and /sup 125/I-IL-2 binding, was studied using lymphocytes stimulated with monoclonal anti-T3 antibodies (Leu-4, OKT3). Lymphocytes, isolated from healthy individuals, were prescreened and classified as Leu-4 responders or non-responders according to 72 h /sup 3/H-thymidine incorporation experiments. Leu-4 non-responder lymphocytes, though capable of normal IL-2R expression and IL-2 secretion when cultured with OKT3 (IgG2a), expressed little to no IL-2R nor secreted IL-2 when stimulated with Leu-4 (IgG1). In addition, the amount of IL-2 secreted by Leu-4 stimulated, Leu-4 responder cells, was one-third- to one-fifth of that detected when OKT3 was used as the stimulant. The addition of recombinant IL-2 (rIL-2) to a Leu-4 stimulated, Leu-4 non-responder lymphocyte culture, resulted in the expression of IL-2R and cellular proliferation, indicating that IL-2 upregulated its biologically relevant receptor. As expected, cyclosporin-A (CSA) inhibited the secretion of IL-2 and subsequent proliferation of Leu-4 stimulated, Leu-4 responder cells. Unexpectedly, however, the expression of IL-2R was also blocked. Exogenous rIL-2 partially reversed the effect of CSA on IL-2R expression and proliferation. The results indicate that IL-2 may provide an additional, required signal for optimal IL-2R expression.

  15. Environmental Assessments (EA) / Environmental Impact Statements...

    Office of Science (SC) Website

    Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630)...

  16. Fermilab | Science | Questions for the Universe | The Particle...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reactor Neutrino Experiment, Daya Bay, China NOvA (proposed), Fermilab, Batavia, IL ... In the longer-term future, experiments such as Daya Bay in China, Double CHOOZ in France, ...

  17. Fermilab Muon Ring Arrives to a Large Crowd of Fans

    SciTech Connect (OSTI)

    2013-08-15

    A very large group of people gathered to watch the muon g-2 ring on its last leg of the big move from Brookhaven National Laboratory in Long Island, NY to Fermilab in Batavia, IL.

  18. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    at Fermilab Batavia, IL. As summer winds down and the tell-tale colors of autumn emerge, the U.S. Department of Energy's Fermi National Accelerator Laboratory once again...

  19. OFermilab OFF-SITE SHORT-TERM HOUSING-2013--2014 Housing Office...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    regarding availability and current prices. Fermi National Accelerator Laboratory I Kirk Road and Pine Street I P.O. Box 500 I Batavia. IL 60510 I 630.840.3000 I www.fnal.gov I...

  20. DOE - Office of Legacy Management -- Museum of Science and Industry - IL 03

    Office of Legacy Management (LM)

    Museum of Science and Industry - IL 03 FUSRAP Considered Sites Site: MUSEUM OF SCIENCE AND INDUSTRY ( IL.03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 57th Street and Lake Shore Drive , Chicago , Illinois IL.03-1 Evaluation Year: 1985 IL.03-2 IL.03-3 Site Operations: The Metallurgical Laboratory and Argonne National Laboratory occupied space in the Museum of Science and Industry from August 15, 1946 to July 15, 1953. Some handling

  1. DOE - Office of Legacy Management -- Eimco Corp - IL 0-01

    Office of Legacy Management (LM)

    Eimco Corp - IL 0-01 FUSRAP Considered Sites Site: Eimco Corp. (IL.0-01 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Palatine , Illinois IL.0-01-1 Evaluation Year: 1987 IL.0-01-1 Site Operations: Conducted laboratory leaf filtration tests IL.0-01-1 Site Disposition: Eliminated - Potential for contamination considered remote based on the limited scope of activities at the site IL.0-01-1 Radioactive Materials Handled: Yes Primary

  2. DOE - Office of Legacy Management -- Hydroblast Corp - IL 0-03

    Office of Legacy Management (LM)

    Hydroblast Corp - IL 0-03 FUSRAP Considered Sites Site: HYDROBLAST CORP. ( IL.0-03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 2550 Northwestern Avenue , Chicago , Illinois IL.0-03-1 Evaluation Year: 1987 IL.0-03-3 Site Operations: Small scale experiment with only 12 uranium rods in 1951. IL.0-03-1 IL.0-03-3 Site Disposition: Eliminated - Potential for contamination considered remote based on the limited scope of activities at the

  3. DOE - Office of Legacy Management -- Sciaky Brothers Inc - IL 0-06

    Office of Legacy Management (LM)

    Sciaky Brothers Inc - IL 0-06 FUSRAP Considered Sites Site: SCIAKY BROTHERS, INC (IL.0-06 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 4915 West 67th Street , Chicago , Illinois IL.0-06-1 Evaluation Year: 1987 IL.0-06-2 Site Operations: One time operation involving stitch welding of uranium in 1953. IL.0-06-1 IL.0-06-2 Site Disposition: Eliminated - Potential for contamination considered remote based on limited operations at the site

  4. DOE - Office of Legacy Management -- C-B Tool Products Co - IL...

    Office of Legacy Management (LM)

    C-B Tool Products Co - IL 31 FUSRAP Considered Sites Site: C-B Tool Products Co. (IL.31 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name:...

  5. R. Tayloe, NuFact'09 Chicago, IL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Quasielastic neutrino scattering: Low energy results (and interpretations) R. Tayloe, NuFact'09 Chicago, IL 7/09 Outline: - Overview of CCQE process - Previous experiments - Current "low-E" results: MiniBooNE,SciBooNE, etal - interpretations, opinions - future   n   - p ν µ µ - W n p ν µ CCQE 2 CCQE motivation Crucial to understand this fundamental process for precision measurements of ν oscillations. Need understanding of underlying theory over wide range of

  6. Argonne Terrestrial Carbon Cycle Data from Batavia Prairie and Agricultural Sites

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Matamala, Roser [ANL; Jastrow, Julie D.; Lesht, Barry [ANL; Cook, David [ANL; Pekour, Mikhail [ANL; Gonzalez-Meler, Miquel A. [University of Illinois at Chicago

    Carbon dioxide fluxes and stocks in terrestrial ecosystems are key measurements needed to constrain quantification of regional carbon sinks and sources and the mechanisms controlling them. This information is required to produce a sound carbon budget for North America. This project examines CO2 and energy fluxes from agricultural land and from restored tallgrass prairie to compare their carbon sequestration potentials. The study integrates eddy covariance measurements with biometric measurements of plant and soil carbon stocks for two systems in northeastern Illinois: 1) long-term cultivated land in corn-soybean rotation with conventional tillage, and 2) a 15 year-old restored prairie that represents a long-term application of CRP conversion of cultivated land to native vegetation. The study contributes to the North American Carbon Program (NACP) by providing information on the magnitude and distribution of carbon stocks and the processes that control carbon dynamics in cultivated and CRP-restored land in the Midwest. The prairie site has been functioning since October 2004 and the agricultural site since July 2005. (From http://www.atmos.anl.gov/ FERMI/index.html)

  7. Association study of schizophrenia and IL-2 receptor {beta} chain gene

    SciTech Connect (OSTI)

    Nimgaonkar, V.L.; Yang, Z.W.; Zhang, X.R.; Brar, J.S.

    1995-10-09

    A case-control association study was conducted in Caucasian patients with schizophrenia (DSM-III-R, n = 42) and unaffected controls (n = 47) matched for ethnicity and area of residence. Serum interleukin-2 receptor (IL-2R) concentrations, as well as a dinucleotide repeat polymorphism in the IL-2RP chain gene, were examined in both groups. No significant differences in IL-2R concentrations or in the distribution of the polymorphism were noted. This study does not support an association between schizophrenia and the IL-2RP gene locus, contrary to the suggestive evidence from linkage analysis in multicase families. 17 refs., 2 tabs.

  8. Cell type-specific roles of Jak3 in IL-2-induced proliferative signal transduction

    SciTech Connect (OSTI)

    Fujii, Hodaka . E-mail: hodaka@med.nyu.edu

    2007-03-16

    Binding of interleukin-2 (IL-2) to its specific receptor induces activation of two members of Jak family protein tyrosine kinases, Jak1 and Jak3. An IL-2 receptor (IL-2R)-reconstituted NIH 3T3 fibroblast cell line proliferates in response to IL-2 only when hematopoietic lineage-specific Jak3 is ectopically expressed. However, the mechanism of Jak3-dependent proliferation in the fibroblast cell line is not known. Here, I showed that Jak3 expression is dispensable for IL-2-induced activation of Jak1 and Stat proteins and expression of nuclear proto-oncogenes in the IL-2R-reconstituted fibroblast cell line. Jak3 expression markedly enhanced these IL-2-induced signaling events. In contrast, Jak3 expression was essential for induction of cyclin genes involved in the G1-S transition. These data suggest a critical role of Jak3 in IL-2 signaling in the fibroblast cell line and may provide further insight into the cell type-specific mechanism of cytokine signaling.

  9. Irreversible inhibition of RANK expression as a possible mechanism for IL-3 inhibition of RANKL-induced osteoclastogenesis

    SciTech Connect (OSTI)

    Khapli, Shruti M.; Tomar, Geetanjali B.; Barhanpurkar, Amruta P.; Gupta, Navita; Yogesha, S.D.; Pote, Satish T.; Wani, Mohan R.

    2010-09-03

    Research highlights: {yields} IL-3 inhibits receptor activator of NF-{kappa}B ligand (RANKL)-induced osteoclastogenesis. {yields} IL-3 inhibits RANKL-induced JNK activation. {yields} IL-3 down-regulates expression of c-Fos and NFATc1 transcription factors. {yields} IL-3 down-regulates RANK expression posttranscriptionally and irreversibly. {yields} IL-3 inhibits in vivo RANK expression. -- Abstract: IL-3, a cytokine secreted by activated T lymphocytes, stimulates the proliferation, differentiation and survival of pluripotent hematopoietic stem cells. In this study, we investigated the mechanism of inhibitory action of IL-3 on osteoclast differentiation. We show here that IL-3 significantly inhibits receptor activator of NF-{kappa}B (RANK) ligand (RANKL)-induced activation of c-Jun N-terminal kinase (JNK). IL-3 down-regulates expression of c-Fos and nuclear factor of activated T cells (NFATc1) transcription factors. In addition, IL-3 down-regulates RANK expression posttranscriptionally in both purified osteoclast precursors and whole bone marrow cells. Furthermore, the inhibitory effect of IL-3 on RANK expression was irreversible. Interestingly, IL-3 inhibits in vivo RANK expression in mice. Thus, we provide the first evidence that IL-3 irreversibly inhibits RANK expression that results in inhibition of important signaling molecules induced by RANKL.

  10. Fermilab F

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    F e r m i N a t i o n a l Ac celerato r L a b o r a tor y P . O . B o x 5 0 0 * B a t a v i a , I l . * 60510-0500 6 3 0 - 8 4 0 - 3 2 1 1 F A X 6 3 0 - 8 4 0 - 2 9 0 0 D i r e c t o r ' s O f f i c e April 15, 2004 Prof. Kevin McFarland Dept. of Physics & Astronomy University of Rochester Rochester NY 14627 Dr. Jorge Morfin Fermilab MS 220 Dear Kevin and Jorge, Thank you for your presentations to the Physics Advisory Committee (PAC). The presentations were well received, and the PAC

  11. File:USDA-CE-Production-GIFmaps-IL.pdf | Open Energy Information

    Open Energy Info (EERE)

    IL.pdf Jump to: navigation, search File File history File usage Illinois Ethanol Plant Locations Size of this preview: 463 599 pixels. Other resolution: 464 600 pixels. Full...

  12. Jobs | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jobs Fermi Site Office (FSO) FSO Home About Organization Chart .pdf file (66KB) Phone List FSO Brochure .pdf file (320KB) Jobs Projects Contract Management NEPA Documents Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 About Jobs Print Text Size: A A A Subscribe FeedbackShare Page Current Open Federal Positions The Fermi Site Office is located in Batavia, Illinois. All

  13. IL.26

    Office of Legacy Management (LM)

    THE RADIOLOGICAL SURVEY AT THE FORMER DOW CHEMICAL COMPANY SITE, MADISON, ILLINOIS c W . ... RADIOLOGICAL SURVEY AT THE FORMER DOW CHEMICAL COMPANY SITE, MADISON, ILLINOIS W. D. ...

  14. Demonstration Assessment of Light-Emitting Diode (LED) Accent Lighting at the Field Museum in Chicago, IL

    SciTech Connect (OSTI)

    Myer, Michael; Kinzey, Bruce R.

    2010-12-10

    This report reviews a demonstration of light-emitting diode (LED) accent lighting compared to halogen (typical) accent lighting in a gallery of the Field Museum in Chicago, IL.

  15. Delivery of human NKG2D-IL-15 fusion gene by chitosan nanoparticles to enhance antitumor immunity

    SciTech Connect (OSTI)

    Yan, Chen; Jie, Leng; Yongqi, Wang; Weiming, Xiao; Juqun, Xi; Yanbing, Ding; Li, Qian; Xingyuan, Pan; Mingchun, Ji; Weijuan, Gong

    2015-07-31

    Nanoparticles are becoming promising carriers for gene delivery because of their high capacity in gene loading and low cell cytotoxicity. In this study, a chitosan-based nanoparticle encapsulated within a recombinant pcDNA3.1-dsNKG2D-IL-15 plasmid was generated. The fused dsNKG2D-IL-15 gene fragment consisted of double extracellular domains of NKG2D with IL-15 gene at downstream. The average diameter of the gene nanoparticles ranged from 200 nm to 400 nm, with mean zeta potential value of 53.8 ± 6.56 mV. The nanoparticles which were loaded with the dsNKG2D-IL-15 gene were uptaken by tumor cells with low cytotoxicity. Tumor cells pre-transfected by gene nanopartilces stimulated NK and T cells in vitro. Intramuscular injection of gene nanoparticles suppressed tumor growth and prolonged survival of tumor-bearing mice through activation of NK and CD8{sup +} T cells. Thus, chitosan-based nanoparticle delivery of dsNKG2D-IL-15 gene vaccine can be potentially used for tumor therapy. - Highlights: • Generation of a nanoparticle for delivery of dsNKG2D-IL-15 gene. • Characterization of the gene nanoparticle. • Antitumor activity mediated by the gene nanoparticle.

  16. 15-CS-1035 ESnet EuropeUS Map_EEX_v4

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Office of Science National Labs Ames ANL BNL FNAL JLAB Ames Laboratory (Ames, IA) Argonne National Laboratory (Argonne, IL) Brookhaven National Laboratory (Upton, NY) Fermi National Accelerator Laboratory (Batavia, IL) Thomas Jefferson National Accelerator Facility (Newport News, VA) LBNL ORNL PNNL PPPL SLAC Lawrence Berkeley National Laboratory (Berkeley, CA) Oak Ridge National Laboratory (Oak Ridge, TN) Pacific Northwest National Laboratory (Richland, WA) Princeton Plasma Physics Laboratory

  17. IL1{beta}-mediated Stromal COX-2 signaling mediates proliferation and invasiveness of colonic epithelial cancer cells

    SciTech Connect (OSTI)

    Zhu, Yingting; Tissue Tech Inc, Miami, FL 33173 ; Zhu, Min; Lance, Peter

    2012-11-15

    COX-2 is a major inflammatory mediator implicated in colorectal inflammation and cancer. However, the exact origin and role of COX-2 on colorectal inflammation and carcinogenesis are still not well defined. Recently, we reported that COX-2 and iNOS signalings interact in colonic CCD18Co fibroblasts. In this article, we investigated whether activation of COX-2 signaling by IL1{beta} in primary colonic fibroblasts obtained from normal and cancer patients play a critical role in regulation of proliferation and invasiveness of human colonic epithelial cancer cells. Our results demonstrated that COX-2 level was significantly higher in cancer associated fibroblasts than that in normal fibroblasts with or without stimulation of IL-1{beta}, a powerful stimulator of COX-2. Using in vitro assays for estimating proliferative and invasive potential, we discovered that the proliferation and invasiveness of the epithelial cancer cells were much greater when the cells were co-cultured with cancer associated fibroblasts than with normal fibroblasts, with or without stimulation of IL1{beta}. Further analysis indicated that the major COX-2 product, prostaglandin E{sub 2}, directly enhanced proliferation and invasiveness of the epithelial cancer cells in the absence of fibroblasts. Moreover, a selective COX-2 inhibitor, NS-398, blocked the proliferative and invasive effect of both normal and cancer associate fibroblasts on the epithelial cancer cells, with or without stimulation of IL-1{beta}. Those results indicate that activation of COX-2 signaling in the fibroblasts plays a major role in promoting proliferation and invasiveness of the epithelial cancer cells. In this process, PKC is involved in the activation of COX-2 signaling induced by IL-1{beta} in the fibroblasts.

  18. Expression of low-, intermediate-, and high-affinity IL-2 receptors on B cell lines derived from patients with undifferentiated lymphoma of Burkitt's and non-Burkitt's types

    SciTech Connect (OSTI)

    Benjamin, D.; Rosolen, A.; Wormsley, S.B.; DeBault, L.E.; Colamonici, O.R. )

    1990-08-01

    IL-2 receptors on T cells exist in at least three forms which differ in their ligand-binding affinity. The low-affinity IL-2 receptor (IL-2R) consists of the 55-kDa Tac protein (p55 alpha), the intermediate-affinity site corresponds to the 70-kDa molecule (p70 beta), and the high-affinity IL-2R consists of a noncovalent heterodimeric structure involving both p55 alpha and p70 beta. We studied 24 B cell lines (8 EBV-negative and 16 EBV-positive) for IL-2R expression in the presence or absence of the tumor promoter, teleocidin. 125I-IL-2 radioreceptor binding assays and crosslinking studies demonstrated the sole expression of p55 alpha in EBV-negative cell lines only, whereas p55 alpha present in EBV-positive cell lines was always associated with p70 beta to construct high-affinity IL-2R. p70 beta was not detected in any of the EBV-negative cell lines, but was expressed on most of the EBV-positive cell lines (13 of 16). Our data also indicate that the expression of p55 alpha and p70 beta by radiolabeling correlates with their expression in flow cytometry, and that a large excess of p55 alpha is required to construct high-affinity IL-2R. Coexpression of p55 alpha and p70 beta on human B cells contributed to constructing high-affinity IL-2R hybrid complex as shown by rapid association rate contributed by p55 alpha and slow dissociation rate by p70 beta; teleocidin's ability to induce p55 alpha on cell lines which express p70 beta only, resulting in appearance of high-affinity IL-2R; and blocking p55 alpha by anti-Tac mAb in cell lines which constitutively express high-affinity IL-2R eliminated both high- and low-affinity components. The existence of low, intermediate, and high IL-2R on human B cells bears important future implications for understanding the mechanism of IL-2 signaling and the role of IL-2 in B cell activation, proliferation, and differentiation.

  19. Eu3+ as a dual probe for the determination of IL anion donor power: A combined luminescence spectroscopic and electrochemical approach

    SciTech Connect (OSTI)

    Babai, Arash; Kopiec, Gabriel; Lackmann, Anastasia; Mallick, Bert; Pitula, Slawomir; Tang, Sifu; Mudring, Anja-Verena

    2014-04-01

    This work is aimed at giving proof that Eu(Tf2N)(3) (Tf2N = bis(trifluoromethanesulfonyl)amide) can act as both an optical and electrochemical probe for the determination of the Lewis acidity of an ionic liquid anion. For that reason the luminescence spectra and cyclic voltammograms of dilute solutions of Eu(Tf2N)(3) in various ionic liquids were investigated. The Eu2+/3+ redox potential in the investigated ILs can be related to the Lewis basicity of the IL anion. The IL cation had little influence. The lower the determined halfwave potential, the higher the IL anion basicity. The obtained ranking can be confirmed by luminescence spectroscopy where a bathochromic shift of the D-5(0) -> F-7(4) transition indicates a stronger Lewis basicity of the IL anion. (C) 2014 Published by Elsevier B.V.

  20. Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling

    SciTech Connect (OSTI)

    Zhang, Bing; Liu, Caini; Qian, Wen; Han, Yue; Li, Xiaoxia; Deng, Junpeng

    2014-05-01

    Crystal structure of the SEFIR domain from human IL-17 receptor A provides new insights into IL-17 signaling. Interleukin 17 (IL-17) cytokines play a crucial role in mediating inflammatory and autoimmune diseases. A unique intracellular signaling domain termed SEFIR is found within all IL-17 receptors (IL-17Rs) as well as the key adaptor protein Act1. SEFIR-mediated protein–protein interaction is a crucial step in IL-17 cytokine signaling. Here, the 2.3 Å resolution crystal structure of the SEFIR domain of IL-17RA, the most commonly shared receptor for IL-17 cytokine signaling, is reported. The structure includes the complete SEFIR domain and an additional α-helical C-terminal extension, which pack tightly together to form a compact unit. Structural comparison between the SEFIR domains of IL-17RA and IL-17RB reveals substantial differences in protein topology and folding. The uniquely long insertion between strand βC and helix αC in IL-17RA SEFIR is mostly well ordered, displaying a helix (αCC′{sub ins}) and a flexible loop (CC′). The DD′ loop in the IL-17RA SEFIR structure is much shorter; it rotates nearly 90° with respect to the counterpart in the IL-17RB SEFIR structure and shifts about 12 Å to accommodate the αCC′{sub ins} helix without forming any knots. Helix αC was identified as critical for its interaction with Act1 and IL-17-stimulated gene expression. The data suggest that the heterotypic SEFIR–SEFIR association via helix αC is a conserved and signature mechanism specific for IL-17 signaling. The structure also suggests that the downstream motif of IL-17RA SEFIR together with helix αC could provide a composite ligand-binding surface for recruiting Act1 during IL-17 signaling.

  1. HIA 2015 DOE Zero Energy Ready Home Case Study: Evolutionary Home Builders, The Adaptation Home, Geneva, IL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Evolutionary Home Builders The Adaptation Home Geneva, IL DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies

  2. ENVIRONMENTAL IlONITORING REPORT FOR THE NEVADA TEST SITE AND OTHER TEST AREAS USED FOR UNDERGROUND NUCLEAR DETONATIONS

    Office of Legacy Management (LM)

    IlONITORING REPORT FOR THE NEVADA TEST SITE AND OTHER TEST AREAS USED FOR UNDERGROUND NUCLEAR DETONATIONS January through December 1975 Nonitoring Operations Division Environmental Monitoring and Support Laboratory U.S. ENVIRONMENTAL PROTECTION AGENCY Las Vegas, Nevada 89114 APRIL 1976 This work performed under a Memorandum of Understanding No. AT(26-1)-539 for the U . S . ENERGY RESEARCH & DEVELOPMENT ADMINISTRATION EMSL-LV-5 39-4 May 1976 ENVIRONMENTAL 14ONITORING REPORT FOR THE NEVADA

  3. Facile fabrication of rutile monolayer films consisting of well crystalline nanorods by following an IL-assisted hydrothermal route

    SciTech Connect (OSTI)

    Peng Peng; Liu Xiaodi; Sun, Chuansheng; Ma Jianmin; Zheng Wenjun

    2009-05-15

    In this study, rutile films consisting of rectangular nanorods were facilely deposited on glass substrates from strongly acid solution of TiCl{sub 4}. The highly ordered array of nanorods was realized in presence of ionic liquid (IL) of [Bmim]Br by following a hydrothermal process. In this process, Degussa P25 nanoparticles served as seeds that were pre-deposited on the substrates to facilitate the array of rutile nanorods. X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectrum were used to characterize the obtained nanorod films. The measurements showed that the nanorods were rectangular with width of 100-200 nm and length of more than 1 {mu}m, and grew up typically along c-axis to form the arrays against the substrate. The presence of IL was found vital for the formation of rutile nanorods, and the suitable molar ratio of [Bmim]Br to TiCl{sub 4} ranged from 500:1 to 1500:1. The excessive [Bmim]Br may hinder the precipitation of rutile particles. - Graphical abstract: The rutile film consisting of rectangular nanorods is successfully deposited on glass substrate in presence of ionic liquid (IL) of [Bmim]Br. The nanorods were rectangular with width of 100-200 nm and length of more than 1 {mu}m, which grew up typically along c-axis to form the arrays against the substrate.

  4. IL-2R{gamma} gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease

    SciTech Connect (OSTI)

    Henthorn, P.S.; Fimiani, V.M.; Patterson, D.F.

    1994-09-01

    X-linked severe combined immunodeficiency (SCID) is characterized by profound defects in cellular and humoral immunity and, in humans, is associated with mutations in the gene for the {gamma} chain of the IL-2 receptor (IL-2R{gamma}). We have examined this gene in a colony of dogs established from a single X-linked SCID carrier female. Affected dogs have a 4-bp deletion in the first exon of the IL-2R{gamma} gene, which precludes the production of a functional protein, demonstrating that the canine disease is a true homologue of human X-linked SCID. 37 refs., 3 figs.

  5. National Environmental Policy Act (NEPA) Documents | U.S. DOE Office of

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science (SC) National Environmental Policy Act (NEPA) Documents Fermi Site Office (FSO) FSO Home About Projects Contract Management NEPA Documents Categorical Exclusion Determinations Environmental Assessments and Environmental Impact Statements Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 National Environmental Policy Act (NEPA) Documents Print Text Size: A A A

  6. Memorandum of Understanding (Technical Report) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Memorandum of Understanding Citation Details In-Document Search Title: Memorandum of Understanding No abstract prepared. Authors: Gustafson, Richard ; Lehman, Alex ; Crisler, Michael ; Streets, Jon ; /Fermilab /Michigan U. Publication Date: 1999-12-20 OSTI Identifier: 1000254 Report Number(s): FERMILAB-PROPOSAL-0917 TRN: US201101%%146 DOE Contract Number: AC02-07CH11359 Resource Type: Technical Report Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring Org: USDOE

  7. Superconductivity at Dawn of the Iron Age (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    (Johns Hopkins University) Publication Date: 2010-03-03 OSTI Identifier: 1017174 DOE Contract Number: AC02-07CH11359 Resource Type: Conference Resource Relation: Conference: Fermilab Colloquia, Fermi National Accelerator Laboratory (FNAL), Batvia, Illinois (United States), presented on March 03, 2010 Research Org: FNAL (Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States)) Sponsoring Org: USDOE Office of Science (SC) Country of Publication: United States Language: English

  8. Annual Users Meeting (Journal Article) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Journal Article: Annual Users Meeting Citation Details In-Document Search Title: Annual Users Meeting Authors: Gustafson, Richard Publication Date: 1982-01-01 OSTI Identifier: 1128382 Report Number(s): FERMILAB-PUB-82-131 DOE Contract Number: AC02-07CH11359 Resource Type: Journal Article Research Org: Fermi National Accelerator Laboratory (FNAL), Batavia, IL Sponsoring Org: USDOE Office of Science (SC), High Energy Physics (HEP) (SC-25) Country of Publication: United States Language: English

  9. Categorical Exclusion (CX) Determinations | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Categorical Exclusion (CX) Determinations Fermi Site Office (FSO) FSO Home About Projects Contract Management NEPA Documents Categorical Exclusion Determinations Environmental Assessments and Environmental Impact Statements Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 National Environmental Policy Act (NEPA) Documents Categorical Exclusion (CX) Determinations Print

  10. MicroBooNE Proposal Addendum March

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MicroBooNE Proposal Addendum March 3, 2008 H. Chen, G. de Geronimo, J. Farrell, A. Kandasamy, F. Lanni, D. Lissauer, D. Makowiecki, J. Mead, V. Radeka, S. Rescia, J. Sondericker, B. Yu Brookhaven National Laboratory, Upton, NY L. Bugel, J. M. Conrad, Z. Djurcic, V. Nguyen, M. Shaevitz, W. Willis ‡ Columbia University, New York, NY C. James, S. Pordes, G. Rameika Fermi National Accelerator Laboratory, Batavia, IL C. Bromberg, D. Edmunds Michigan State University, Lansing, MI P. Nienaber St.

  11. Superconductivity at Dawn of the Iron Age (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Johns Hopkins University, Baltimore, Maryland, United States Publication Date: 2010-03-03 OSTI Identifier: 987784 DOE Contract Number: AC02-07CH11359 Resource Type: Conference Resource Relation: Conference: Fermilab Colloquia, Fermi National Accelerator Laboratory (FNAL), Batvia, Illinois (United States), presented on March 03, 2010 Publisher: Fermi Colloquia Online Research Org: FNAL (Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States)) Sponsoring Org: USDOE Office of

  12. EA-1943: Long Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) at Fermilab, Batavia, Illinois and the Sanford Underground Research Facility, Lead, South Dakota

    Broader source: Energy.gov [DOE]

    This EA evaluates the environmental impacts of using the existing Main Injector Accelerator at Fermilab to produce a pure beam of muon neutrinos. The neutrinos would be examined at a "near detector" proposed to be constructed at Fermilab, and at a "far detector," at the Sanford Underground Research Facility (SURF) in Lead, South Dakota. NOTE: This Project was previously designated (DOE/EA-1799).

  13. Type B Accident Investigation Board Report on the September 4, 1998, Flammable Liquid Fire/Explosion at Fermi National Accelerator Laboratory, Batavia, Illinois

    Broader source: Energy.gov [DOE]

    This report is an independent product of the Type B Accident Investigation Board appointed by John P. Kennedy, Acting Manager, Chicago Operations Office, U.S. Department of Energy.

  14. Type B Accident Investigation Board Report on the October 22, 1997, Electrical Arc Blast at Building F-Zero Fermi National Accelerator Laboratory, Batavia, Illinois

    Broader source: Energy.gov [DOE]

    This report is an independent product of the Type B Accident Investigation Board appointed by Cherri J. Langenfeld, Manager, Chicago Operations Office, U.S. Department of Energy.

  15. EA-1943: Construction and Operation of the Long Baseline Neutrino Facility and Deep Underground Neutrino Experiment at Fermilab, Batavia, Illinois, and Sanford Underground Research Facility, Lead, South Dakota

    Broader source: Energy.gov [DOE]

    This EA evaluates the environmental impacts of using the existing Main Injector Accelerator at Fermilab to produce a pure beam of muon neutrinos. The neutrinos would be examined at a "near detector" proposed to be constructed at Fermilab, and at a "far detector," at the Sanford Underground Research Facility (SURF) in Lead, South Dakota. NOTE: This Project was previously designated (DOE/EA-1799).

  16. HIA 2015 DOE Zero Energy Ready Home Case Study: BrightLeaf Homes, McCormick Avenue, Brookfield, IL

    Energy Savers [EERE]

    BrightLeaf Homes McCormick Avenue Brookfield, IL DOE ZERO ENERGY READY HOME(tm) The U.S. Department of Energy invites home builders across the country to meet the extraordinary levels of excellence and quality specified in DOE's Zero Energy Ready Home program (formerly known as Challenge Home). Every DOE Zero Energy Ready Home starts with ENERGY STAR Certified Homes Version 3.0 for an energy-efficient home built on a solid foundation of building science research. Advanced technologies are

  17. Activation of IL-2 receptor {alpha}-chain gene by individual members of the rel oncogene family in association with serum response factor

    SciTech Connect (OSTI)

    Pierce, J.W.; Jamieson, C.A.; Ross, J.L.

    1995-08-15

    Expression of the IL-2R{alpha} gene is regulated by members of the c-Rel/NF-{kappa}B family of transcription factors binding to the {kappa}B site in the promoter. Previous work has not defined the role of individual members of the c-Rel family in the activation of the IL-2R{alpha} gene. Using the COS cell system, we were able to reconstitute the regulation of the IL-2R{alpha} promoter by expressing cloned Rel family members with serum response factor (SRF). We found that c-rel alone activated the IL-2R{alpha} promoter only weakly but worked with the p50 subunit of NF-{kappa}B (NFKB1) to give a higher level of expression. We showed that c-rel heterodimerizes with p50 and the amount of this heterodimer correlated with the level of IL-2R{alpha} gene expression. Our results provide evidence that c-rel/p50 heterodimers activate gene expression in the context of a cellular promoter. We show that c-rel or p65 can cooperate with SRF in the activation of this promoter and the transactivation by c-rel with SRF was enhanced by p50. Synergistic activation required both {kappa}B an CArG sites, and binding studies show that these that these adjacent sites can be occupied simultaneously. The transactivation observed with cloned transcription factors mimics the physiologic induction of the IL-2R{alpha} gene since multiple sequence elements cooperate to give gene activation. The data support the model that c-rel/p50 or p65 can cooperate with SRF to specifically target the expression of the IL-2R{alpha} gene in activated T cells.

  18. Immunosuppressive effect of the anti-IL-2-receptor monoclonal antibody, AMT-13, on organ-cultured fetal pancreas allograft survival

    SciTech Connect (OSTI)

    Burkhardt, K.; Loughnan, M.S.; Diamantstein, T.; Mandel, T.E.

    1988-11-01

    Recently, prolongation of cardiac allograft survival in mice was reported using a rat anti-IL-2R mAb (AMT-13). However, its immunosuppressive action in vivo, alone and in combination with other immunosuppressants, and its effect on other organ transplants has not been extensively studied. We grafted cultured fetal pancreas from CBA (H-2k) donors to Balb/c (H-2d) mice. Recipients were treated with 10 consecutive daily injections each of 20 micrograms AMT-13 only, or with an additional mild immunosuppression of 350 rads irradiation. Control groups received rat immunoglobulin or 350 rads irradiation. Graft survival and the phenotype of infiltrating cells were assessed histologically and immunocytochemically on days 12, 17, and 21, and soluble IL-2R levels were measured in the serum with a quantitative ELISA in all recipients. Two of five grafts in the AMT-13-treated group had islets on day 12 posttransplantation despite lymphocytic infiltration in all grafts, while at this time all grafts of rat Ig treated control mice were completely rejected with only scar tissue and a few lymphocytes remaining. Additional immunosuppression with 350 rads irradiation had a marked additive effect with AMT-13. Soluble IL-2R levels in the serum of untreated recipients were not elevated compared with normal serum levels, but recipients injected with AMT-13 had multifold increased soluble IL-2R levels. The percentage of IL-2R+ cells in the grafts of AMT-13-treated animals was either normal (less than 5%) or increased (20%) in the additionally irradiated mice, providing strong evidence that the immunosuppressive effect of AMT-13 is not due to a depletion of activated IL-2R+ lymphocytes.

  19. Thermal spray removal of lead-based paint from the viaduct bridge at Rock Island Arsenal, IL. Final report

    SciTech Connect (OSTI)

    Boy, J.H.; Weber, R.A.; Kumar, A.

    1998-06-01

    This report documents a field demonstration at the Rock Island Arsenal, IL, that validated the thermal spray vitrification (TSV) process as a safe and effective technique for removing lead-based paint from a steel bridge. Specially formulated glass was applied in a molten state to painted steel using a conventional thermal spray application system. The molten glass reacts with the paint, and encapsulates the lead. The cooled glass readily cracks and falls off, removing the paint. After onsite remelting of the glass waste to complete the encapsulation process, the final waste product is chemically inert and may be disposed of in a regular landfill. The Illinois Environmental Protection Agency, Division of Air Pollution Control determined that the glass remelt process could be considered a paint-removal operation for which no air quality permit was required.

  20. ROS and NF-{kappa}B are involved in upregulation of IL-8 in A549 cells exposed to multi-walled carbon nanotubes

    SciTech Connect (OSTI)

    Ye Shefang Wu Yihui; Hou Zhenqing; Zhang Qiqing

    2009-02-06

    Carbon nanotubes (CNTs) have potential applications in biosensors, tissue engineering, and biomedical devices because of their unique physico-chemical, electronic and mechanical properties. However, there is limited literature data available concerning the biological properties and toxicity of CNTs. This study aimed to assess the toxicity exhibited by multi-walled CNTs (MWCNTs) and to elucidate possible molecular mechanisms underlying the biological effects of MWCNTs in A549 cells. Exposing A549 cells to MWCNTs led to cell death, changes in cell size and complexity, reactive oxygen species (ROS) production, interleukin-8 (IL-8) gene expression and nuclear factor (NF)-{kappa}B activation. Treatment of A549 cells with antioxidants prior to adding MWCNTs decreased ROS production and abrogated expression of IL-8 mRNA. Pretreatment of A549 cells with NF-{kappa}B inhibitors suppressed MWCNTs-induced IL-8 mRNA expression. These results indicate that MWCNTs are able to induce expression of IL-8 in A549 cells, at least in part, mediated by oxidative stress and NF-{kappa}B activation.

  1. Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Luo, Fei; Xu, Yuan; Ling, Min; Zhao, Yue; Xu, Wenchao; Liang, Xiao; Jiang, Rongrong; Wang, Bairu; Bian, Qian; Liu, Qizhan

    2013-11-15

    Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of STAT3, a transcription activator, and to increased levels of a microRNA, miR-21. Blocking IL-6 with anti-IL-6 antibody and inhibiting STAT3 activation reduced miR-21 expression. For human bronchial epithelial cells, cultured in the presence of anti-IL-6 antibody for 3 days, the arsenite-induced EMT and malignant transformation were reversed. Thus, IL-6, acting on STAT3 signaling, which up-regulates miR-21in an autocrine manner, contributes to the EMT induced by arsenite. These data define a link from inflammation to EMT in the arsenite-induced malignant transformation of HBE cells. This link, mediated through miRNAs, establishes a mechanism for arsenite-induced lung carcinogenesis. - Highlights: Arsenite evokes IL-6 secretion. IL-6 autocrine mediates STAT3 signaling and up-regulates miR-21expression. Inflammation is involved in arsenite-induced EMT.

  2. IL conversion technology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    conversion technology - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs Advanced

  3. Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-?1/IL-2/COX-2/endothelin ET{sub B} receptor cascade

    SciTech Connect (OSTI)

    El-Gowelli, Hanan M.; Helmy, Maged W.; Ali, Rabab M.; El-Mas, Mahmoud M.

    2014-03-01

    Endothelin (ET) signaling provokes nephrotoxicity induced by the immunosuppressant drug cyclosporine A (CSA). We tested the hypotheses that (i): celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, counterbalances renal derangements caused by CSA in rats and (ii) the COX-2/endothelin ET{sub B} receptor signaling mediates the CSA-celecoxib interaction. Ten-day treatment with CSA (20 mg/kg/day) significantly increased biochemical indices of renal function (serum urea, creatinine), inflammation (interleukin-2, IL-2) and fibrosis (transforming growth factor-?{sub 1}, TGF-?{sub 1}). Histologically, CSA caused renal tubular atrophy along with interstitial fibrosis. These detrimental renal effects of CSA were largely reduced in rats treated concurrently with celecoxib (10 mg/kg/day). We also report that cortical glomerular and medullary tubular protein expressions of COX-2 and ET{sub B} receptors were reduced by CSA and restored to near-control values in rats treated simultaneously with celecoxib. The importance of ET{sub B} receptors in renal control and in the CSA-celecoxib interaction was further verified by the findings (i) most of the adverse biochemical, inflammatory, and histopathological profiles of CSA were replicated in rats treated with the endothelin ET{sub B} receptor antagonist BQ788 (0.1 mg/kg/day, 10 days), and (ii) the BQ788 effects, like those of CSA, were alleviated in rats treated concurrently with celecoxib. Together, the data suggest that the facilitation of the interplay between the TGF-?1/IL-2/COX-2 pathway and the endothelin ET{sub B} receptors constitutes the cellular mechanism by which celecoxib ameliorates the nephrotoxic manifestations of CSA in rats. - Highlights: Celecoxib abolishes nephrotoxic manifestations of CSA in rats. Blockade of ETB receptors by BQ788 mimicked the nephrotoxic effects of CSA. CSA or BQ788 reduces renal protein expression of COX-2 and endothelin ETB receptors. Enhanced TGF?1/IL-2/COX2/ETB signaling mediates celecoxib renoprotection.

  4. Pilar Coloma, Bogdan A. Dobrescu, Claudia Frugiuele and Roni Harnik

    Office of Scientific and Technical Information (OSTI)

    for SISSA by <£} Springer Received: January 12, 2016 Accepted: March 30, 2016 Published: April 8, 2016 Dark matter beams at LBNF Pilar Coloma, Bogdan A. Dobrescu, Claudia Frugiuele and Roni Harnik Theory Department, Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510, U.S.A. E-mail: pcoloma@fnal.gov, bdob@fnal.gov, claudiaf@fnal.gov, roni@fnal.gov Abstract: High-intensity neutrino beam facilities may produce a beam of light dark mat- ter when protons strike the target.

  5. Projects | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Projects Fermi Site Office (FSO) FSO Home About Projects Contract Management NEPA Documents Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 Projects Print Text Size: A A A FeedbackShare Page FSO provides oversight to proposed and ongoing science and infrastructure projects at Fermilab. The latest developments in accelerator and detector technology make possible promising

  6. Resources | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Resources Fermi Site Office (FSO) FSO Home About Projects Contract Management NEPA Documents Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 Resources Print Text Size: A A A FeedbackShare Page Virtual Contract Management Team The Site Office operates as a virtual contract management team working to provide the necessary information to ensure that the Contracting Officers

  7. About | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    About Fermi Site Office (FSO) FSO Home About Organization Chart .pdf file (66KB) Phone List FSO Brochure .pdf file (320KB) Jobs Projects Contract Management NEPA Documents Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 About Print Text Size: A A A FeedbackShare Page As part of The Fermi Site Office's (FSO) Mission, Vision, and Principles .pptx file (148KB), the FSO

  8. Contract Management | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Contract Management Fermi Site Office (FSO) FSO Home About Projects Contract Management NEPA Documents Resources Contact Information Fermi Site Office U.S. Department of Energy MS 118 P.O. Box 2000 Kirk Road and Pine Street Batavia, IL 60510 P: (630) 840-3281 F: (630) 840-3285 Contract Management Print Text Size: A A A FeedbackShare Page The FSOBusiness and Contract Support .pdf file (258KB) Team implements the timely execution of all Fermi Research Alliance (FRA) External link management and

  9. TGF-{beta}1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-{kappa}B/IL-6/MMP-2

    SciTech Connect (OSTI)

    Binker, Marcelo G.; CBRHC Research Center, Buenos Aires ; Binker-Cosen, Andres A.; Gaisano, Herbert Y.; Cosen, Rodica H. de; Cosen-Binker, Laura I.

    2011-02-04

    Research highlights: {yields} Rac1 mediates TGF-{beta}1-induced SW1990 invasion through MMP-2 secretion and activation. {yields} NADPH-generated ROS act downstream of Rac1 in TGF-{beta}1-challenged SW1990 cells. {yields} TGF-{beta}1-stimulated ROS activate NF-{kappa}B in SW1990 cells. {yields} NF{kappa}B-induced IL-6 release is required for secretion and activation of MMP-2 in SW1990 cells. -- Abstract: Human pancreatic cancer invasion and metastasis have been found to correlate with increased levels of active matrix metalloproteinase 2 (MMP-2). The multifunctional cytokine transforming growth factor beta 1 (TGF-{beta}1) has been shown to increase both secretion of MMP-2 and invasion by several pancreatic cancer cell types. In the present study, we investigated the signaling pathway involved in TGF-{beta}1-promoted MMP-2 secretion and invasion by human pancreatic cancer cells SW1990. Using specific inhibitors, we found that stimulation of these tumor cells with TGF-{beta}1 induced secretion and activation of the collagenase MMP-2, which was required for TGF-{beta}1-stimulated invasion. Our results also indicate that signaling events involved in TGF-{beta}1-enhanced SW1990 invasiveness comprehend activation of Rac1 followed by generation of reactive oxygen species through nicotinamide adenine dinucleotide phosphate-oxidase, activation of nuclear factor-kappa beta, release of interleukin-6, and secretion and activation of MMP-2.

  10. US ENC IL Site Consumption

    U.S. Energy Information Administration (EIA) Indexed Site

    Energy Consumption Survey www.eia.govconsumptionresidential Space heating Water heating Air conditioning Appliances, electronics, lighting Household Energy Use in Illinois ...

  11. Zinc ferrite nanoparticles activate IL-1b, NFKB1, CCL21 and NOS2 signaling to induce mitochondrial dependent intrinsic apoptotic pathway in WISH cells

    SciTech Connect (OSTI)

    Saquib, Quaiser; Al-Khedhairy, Abdulaziz A.; Ahmad, Javed; Siddiqui, Maqsood A.; Dwivedi, Sourabh; Khan, Shams T.; Musarrat, Javed

    2013-12-01

    The present study has demonstrated the translocation of zinc ferrite nanoparticles (ZnFe{sub 2}O{sub 4}-NPs) into the cytoplasm of human amnion epithelial (WISH) cells, and the ensuing cytotoxicity and genetic damage. The results suggested that in situ NPs induced oxidative stress, alterations in cellular membrane and DNA strand breaks. The [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) and neutral red uptake (NRU) cytotoxicity assays indicated 64.48 1.6% and 50.73 2.1% reduction in cell viability with 100 ?g/ml of ZnFe{sub 2}O{sub 4}-NPs exposure. The treated WISH cells exhibited 1.2-fold higher ROS level with 0.9-fold decline in membrane potential (??m) and 7.4-fold higher DNA damage after 48 h of ZnFe{sub 2}O{sub 4}-NPs treatment. Real-time PCR (qPCR) analysis of p53, CASP 3 (caspase-3), and bax genes revealed 5.3, 1.6, and 14.9-fold upregulation, and 0.18-fold down regulation of bcl 2 gene vis--vis untreated control. RT{sup 2} Profiler PCR array data elucidated differential up-regulation of mRNA transcripts of IL-1b, NFKB1, NOS2 and CCL21 genes in the range of 1.5 to 3.7-folds. The flow cytometry based cell cycle analysis suggested the transfer of 15.2 2.1% (p < 0.01) population of ZnFe{sub 2}O{sub 4}-NPs (100 ?g/ml) treated cells into apoptotic phase through intrinsic pathway. Over all, the data revealed the potential of ZnFe{sub 2}O{sub 4}-NPs to induce cellular and genetic toxicity in cells of placental origin. Thus, the significant ROS production, reduction in ??m, DNA damage, and activation of genes linked to inflammation, oxidative stress, proliferation, DNA damage and repair could serve as the predictive toxicity and stress markers for ecotoxicological assessment of ZnFe{sub 2}O{sub 4}-NPs induced cellular and genetic damage. - Highlights: First report on the molecular toxicity of ZnFe{sub 2}O{sub 4}-NPs in cells of placental origin WISH cells treated with ZnFe{sub 2}O{sub 4}-NPs exhibited cytoplasmic localization of NPs. ZnFe{sub 2}O{sub 4}-NPs induce DNA damage and mitochondrial dysfunction in WISH cells. ZnFe{sub 2}O{sub 4}-NPs activate inflammatory and oxidative stress signaling in WISH cells. Elevation of p53, CASP 3, bax and bcl 2 genes affirms intrinsic apoptotic pathway.

  12. Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism

    SciTech Connect (OSTI)

    Murugaiyan, Jayaseelan; Rockstroh, Maxie; Wagner, Juliane; Baumann, Sven; Schorsch, Katrin; Trump, Saskia; Lehmann, Irina; Bergen, Martin von; Tomm, Janina M.

    2013-06-15

    There is a clear evidence that environmental pollutants, such as benzo[a]pyrene (B[a]P), can have detrimental effects on the immune system, whereas the underlying mechanisms still remain elusive. Jurkat T cells share many properties with native T lymphocytes and therefore are an appropriate model to analyze the effects of environmental pollutants on T cells and their activation. Since environmental compounds frequently occur at low, not acute toxic concentrations, we analyzed the effects of two subtoxic concentrations, 50 nM and 5 ?M, on non- and activated cells. B[a]P interferes directly with the stimulation process as proven by an altered IL-2 secretion. Furthermore, B[a]P exposure results in significant proteomic changes as shown by DIGE analysis. Pathway analysis revealed an involvement of the AhR independent Nrf2 pathway in the altered processes observed in unstimulated and stimulated cells. A participation of the Nrf2 pathway in the change of IL-2 secretion was confirmed by exposing cells to the Nrf2 activator tBHQ. tBHQ and 5 ?M B[a]P caused similar alterations of IL-2 secretion and glutamine/glutamate metabolism. Moreover, the proteome changes in unstimulated cells point towards a modified regulation of the cytoskeleton and cellular stress response, which was proven by western blotting. Additionally, there is a strong evidence for alterations in metabolic pathways caused by B[a]P exposure in stimulated cells. Especially the glutamine/glutamate metabolism was indicated by proteome pathway analysis and validated by metabolite measurements. The detrimental effects were slightly enhanced in stimulated cells, suggesting that stimulated cells are more vulnerable to the environmental pollutant model compound B[a]P. - Highlights: B[a]P affects the proteome of Jurkat T cells also at low concentrations. Exposure to B[a]P (50 nM, 5 ?M) did not change Jurkat T cell viability. Both B[a]P concentrations altered the IL-2 secretion of stimulated cells. 608 different protein spots of Jurkat T cells were quantified using 2-DE-DIGE. Pathway analysis identified Nrf2 and AhR pathway as regulated.

  13. actos_il_v05.ai

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Administration and project management Acquisition and Project Management Office volunteers get up-close look at Office of Secure Transportation exercise Contracting professionals from the NNSA Acquisition & Project Management (APM) Field Program Section (FPS) recently served as role players for Office of Secure Transportation (OST) training exercises in Arkansas and Oklahoma. OST Federal Agents transport U.S. nuclear weapons, components and... SNL Starting Points Sandia Field Office Home

  14. Press Pass - Press Release - Higgs mass constraints

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    -mass-constraints-20100726-images.html Fermilab experiments narrow allowed mass range for Higgs boson Batavia, Ill.New constraints on the elusive Higgs particle are more...

  15. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    sdahl@fnal.gov For Immediate Release Children's Science Adventures at Fermilab Offer Summer Fun - and Learning, Too BATAVIA, Illinois-Summertime is a bright season of...

  16. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on Weakly Interacting Massive Particles that could make up most of the matter of our universe BATAVIA, Ill.- With the first data from their underground observatory in Northern...

  17. EA-1943: Long Baseline Neutrino Facility/Deep Underground Neutrino...

    Broader source: Energy.gov (indexed) [DOE]

    May 27, 2015 EA-1943: Draft Environmental Assessment Long Baseline Neutrino FacilityDeep Underground Neutrino Experiment (LBNFDUNE) at Fermilab, Batavia, Illinois and the...

  18. EA-1943: Finding of No Significant Impact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    Construction and Operation of the Long Baseline Neutrino Facility and Deep Underground Neutrino Experiment at Fermilab, Batavia, Illinois, and Sanford Underground Research...

  19. A

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David W. Schmitz This dissertation presents measurements ... BooNE) located at Fermilab in Batavia, Illinois. First, ... A 506 (2003) 250. 126 J. Allison et al. GEANT4 ...

  20. EA-1943: Finding of No Significant Impact

    Broader source: Energy.gov [DOE]

    Construction and Operation of the Long Baseline Neutrino Facility and Deep Underground Neutrino Experiment at Fermilab, Batavia, Illinois, and Sanford Underground Research Facility, Lead, South Dakota

  1. EA-1943: Final Environmental Assessment

    Office of Energy Efficiency and Renewable Energy (EERE)

    Construction and Operation of the Long Baseline Neutrino Facility and Deep Underground Neutrino Experiment at Fermilab, Batavia, Illinois, and Sanford Underground Research Facility, Lead, South Dakota

  2. Fermilab | Newsroom | Press Releases | March 27, 2012: Fermilab...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    technicians and mathematicians Batavia, Ill. -- High school students can learn about high-tech career options at the Science, Technology, Engineering and Mathematics (STEM)...

  3. DELTEC INC | Open Energy Information

    Open Energy Info (EERE)

    4230 Grissom Drive Place: Batavia, Ohio Zip: 45103 Sector: Vehicles Product: Manufacturing Phone Number: 513-732-0800 Website: www.deltec-inc.com Coordinates: 39.077661,...

  4. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    email bland@fnal.gov For Immediate Release Fermilab Colloquium Series Offers Free Public Talks on World Energy Situation Beginning Wednesday, April 13 BATAVIA,...

  5. Clermont County, Ohio: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Batavia, Ohio Bethel, Ohio Chilo, Ohio Day Heights, Ohio Felicity, Ohio Loveland, Ohio Milford, Ohio Moscow, Ohio Mount Carmel, Ohio Mount Repose, Ohio Mulberry, Ohio Neville, Ohio...

  6. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    26, 1999 For immediate release PRESS ADVISORY: SIGN UP FOR COVERAGE OF MAIN INJECTOR DEDICATION ON TUESDAY, JUNE 1; RICHARDSON, HASTERT TO SPEAK Batavia, Ill.Secretary of...

  7. Measurement of the double differential diject mass cross section in pp(bar) collisions at sqrt(s) = 1.96 TeV

    SciTech Connect (OSTI)

    Rominsky, Mandy Kathleen; /Oklahoma U.

    2009-07-01

    This thesis presents the analysis of the double differential dijet mass cross section, measured at the D0 detector in Batavia, IL, using p{bar p} collisions at a center of mass energy of {radical}s = 1.96 TeV. The dijet mass was calculated using the two highest p{sub T} jets in the event, with approximately 0.7 fb{sup -1} of data collected between 2004 and 2005. The analysis was presented in bins of dijet mass (M{sub JJ}) and rapidity (y), and extends the measurement farther in M{sub JJ} and y than any previous measurement. Corrections due to detector effects were calculated using a Monte Carlo simulation and applied to data. The errors on the measurement consist of statistical and systematic errors, of which the Jet Energy Scale was the largest. The final result was compared to next-to-leading order theory and good agreement was found. These results may be used in the determination of the proton parton distribution functions and to set limits on new physics.

  8. #iWNCD W ONTAININO Il@MQWm;

    Office of Legacy Management (LM)

    on the urgency and the need for autho -,. ,n - this premiumpayment.) l-13-55 loiD. 365 duPont l topa 4-26-55 pa and the faettbat the doorstop8 on the knles steel in the ...

  9. Quadrennial Energy Review Stakeholder Meeting #9: Chicago, IL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of federal water resources, including commercial navigation and flood risk management and environmental restoration. 2. As part of a 2012 Executive Order, the Army Corps of ...

  10. MEMORANDUM TO: FILE F3on: A 6 IL

    Office of Legacy Management (LM)

    .Z,+,ECI-INVOLVE?EXT AT SITE . ---... ---... ---- . 1, Control c Health Physics Protection . 0 AECMED managed operations G Little or None 3 AECtlED responsible for ...

  11. Increasing Sugar Yields with IL-final-sm

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ionic Liquid Processing Increasing sugar yields from diverse biomass feedstock with ionic liquid processing and cultivation of renewable ionic liquids Liberating Sugars from Biomass Lignocellulose, one of the most abundant plants on Earth, has the potential to displace a substantial portion of the fossil fuels currently consumed within the transportation sector. Converting lignocellulose to biofuels requires the disruption of the lignin-carbohydrate complex within the plant and conversion into

  12. Snapshots of the IL-4 Receptor Ternary Complexes: An Opportunity...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    protein causing movements within the transmembrane region, which conveys the signal more directly across the membrane, where this latter mechanism is beyond the scope...

  13. MIN IMI IlI New Data Series

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Change, Petroleum Products Supplied, and Ending Stocks ... 40 3.1b Imports, Exports, and Net Imports ... 41 3.2 Crude Oil Supply and...

  14. QER Public Meeting in Chicago, IL: Rail, Barge, Truck Transportation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... - Statement PDF icon John Gray, Senior Vice President for Policy and Economics, the Association of American Railroads (AAR) - Statement PDF icon John Gray, Senior Vice President ...

  15. Increasing Sugar Yields with IL-final-sm

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a feedstock agnostic ionic liquid pretreatment process that: Agriculture Waste Woody Biomass Mixed Feedstocks Municipal Solid Waste (MSW) Biofuels Program Contact: Blake...

  16. Quadrennial Energy Review August 8, 2014 Chicago , Il.

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Perspective. Ernie Perry, PhD. ebperry@wisc.edu University Of Wisconsin - Madison 2 ... Freight Coalition Ernie Perry, PhD University of Wisconsin - Madison ebperry@wisc.edu

  17. Press Pass - Press Release - Single Top

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DZero finds evidence of rare single top quark; Observation marks a step closer to finding Higgs boson Batavia, Ill.--Scientists of the DZero collaboration at the Department of...

  18. Press Pass - Press Release - Higgs mass constraints

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    exclude significant fraction of Higgs territory Batavia, Ill.-The territory where the Higgs boson may be found continues to shrink. The latest analysis of data from the CDF and...

  19. Fermilab | Newsroom | Press Releases | 2010 | Fatality at Fermilab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fermi National Accelerator Laboratory. Around 10:50 a.m. employees investigating a noise found a young female lying in the atrium of Wilson Hall. Batavia paramedics pronounced...

  20. CX-006812: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Demolition of Site 12 BarnCX(s) Applied: B1.23Date: 09/12/2011Location(s): Batavia, IllinoisOffice(s): Science, Fermi Site Office

  1. CX-003133: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    D-Zero Experiment Emergency Generator Fuel Tank Replacement ProjectCX(s) Applied: B1.3Date: 07/13/2010Location(s): Batavia, IllinoisOffice(s): Fermi Site Office, Science

  2. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Office, 630-840-3094, sdahl@fnal.gov Children's Science Adventures at Fermilab Offer Summer Fun - and Learning, Too BATAVIA, Illinois-Summertime is a bright season of...

  3. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    release MiniBooNE opens the box Results from Fermilab experiment resolve long-standing neutrino question BATAVIA, Illinois-Scientists of the MiniBooNE1 experiment at the...

  4. EA-1570: Final Environmental Assessment

    Broader source: Energy.gov [DOE]

    Construction and Operation of Neutrinos at the Main Injector Off-Axis Electron Neutrino (νe) Appearance Experiment (NOvA) at the Fermi National Accelerator Laboratory, Batavia, Illinois, and St. Louis County, Minnesota

  5. Fermilab | Tevatron | Tevatron Symposium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    society graphic June 11, 2012 Ramsey Auditorium Fermilab Batavia, Illinois, USA 1:00 p.m. Symposium 6:00 p.m. Reception Featuring speakers honoring three decades of Tevatron...

  6. Fermilab | Newsroom | Press Releases | November 12, 2012: Fermilab...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Batavia, Ill., invited 50 amateur and professional photographers to take pictures in five high-tech areas of the lab, areas not part of the public tour. The photographers, chosen...

  7. CX-002935: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Illinois Accelerator Research Center (IARC)CX(s) Applied: B1.15Date: 06/30/2010Location(s): Batavia, IllinoisOffice(s): Fermi Site Office, Science

  8. CX-006220: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Phase and Frequency Locked Magnetrons for Superconducting Radio Frequency Sources, Phase IICX(s) Applied: B3.6Date: 06/24/2011Location(s): Batavia, IllinoisOffice(s): Science, Fermi Site Office

  9. CX-002826: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Industrial Area Site Upgrade ProjectCX(s) Applied: B1.15Date: 06/23/2010Location(s): Batavia, IllinoisOffice(s): Fermi Site Office, Science

  10. CX-005976: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Demolition of Trailers T116, T124, T134CX(s) Applied: B1.23Date: 05/17/2011Location(s): Batavia, IllinoisOffice(s): Science, Fermi Site Office

  11. CX-003124: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    A1 to CDF Paving ProjectCX(s) Applied: B1.3Date: 07/08/2010Location(s): Batavia, IllinoisOffice(s): Fermi Site Office, Science

  12. CX-003134: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    NEA/NEB/NS8 Deactivation and DecommissioningCX(s) Applied: B1.23Date: 07/16/2010Location(s): Batavia, IllinoisOffice(s): Fermi Site Office, Science

  13. CX-006796: Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Industrial Building (IB)-1 Mezzanine RenovationCX(s) Applied: B1.15Date: 09/09/2011Location(s): Batavia, IllinoisOffice(s): Science, Fermi Site Office

  14. Press Pass - Press Release - CDF B_s

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    official: They have discovered the quick-change behavior of the B-sub-s meson, which switches between matter and antimatter 3 trillion times a second. BATAVIA, Illinois -...

  15. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Particle Physics and Fermilab this Friday (March 27) at 8 p.m. at Fermilabs Ramsey Auditorium in Batavia, Illinois. Fermilab Director Pier Oddone will talk about the...

  16. Press Pass - Press Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for Students and Teachers, Saturday, October 8 from 8 a.m. to 3:15 p.m. at Fermilab's Ramsey Auditorium BATAVIA, Illinois-Some of the hottest topics in the field of physics today,...

  17. Public Activities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Arts, Lecture and Film Series On the evening of a performance, all visitors may enter through the Pine St. or the Batavia Rd. entrance. Inform the security guard that you are...

  18. Kuhn Village Barn

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    turn right at the first stop sign. The barn is the second building on the right. Take Kirk Rd. to Pine St. in Batavia. Turn east onto Pine St. Go past the guardhouse (stopping...

  19. Fermilab | Tritium at Fermilab | Tritium in Sanitary Sewers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tritium in Sanitary Sewers chart graphic As part of our environmental monitoring program, we routinely sample our sanitary sewer water that is discharged to wastewater treatment systems in the cities of Batavia and Warrenville. Samples taken from sanitary sewer water discharged to the Batavia Wastewater Treatment Facility show small but measurable levels of tritium. All tritium levels found on site are well below any federal health and environmental standards. No tritium has been detected in

  20. Inquiring Minds - Questions About Physics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Particles from Batavia to Soudan Tom, You asked: I have been reading various pages on the Fermi website and I'm unclear how the particles to be tested get from Batavia to Soudan. Is there a physical connection like a pipeline or is this something that just happens through the earth? Sorry for what's probably a very basic question but I couldn't quite understand that point. Are there articles that explain how this happens? Thanks! Tom Hi Tom, I am a physicist working on the NuMI/MINOS project

  1. Impacts of antropogenic contaminants on vegetation and groundwater chemistry in a fen complex (IL)

    SciTech Connect (OSTI)

    Nuzzo, V.A.; Hensel, B.; Panno, S.; Cartwright, K.; Krapac, I. Illinois State Geological Survey, Champaign )

    1993-06-01

    Residential development within the watershed of a fen complex has resulted in encroachment of ground-water borne anthropogenic contaminants into 3 high quality fens. Groundwater samples were collected from peat and marl and analyzed for inorganic constituents. Height and density of Typha angustifolia L. and Scirpus acutus Muhl. were recorded in belt transects coincident with ground-water samples. Contaminant plumes from septic systems of houses near the fens had higher Na, Cl, NO[sub 3], and TDS levels than uncontaminated areas of the fens. Typha density increased significantly as Na, Cl, CL/SO[sub 4], and TDS levels increased; Scirpus occurred only where pH [ge] 7.1 (X[sub 2]=11.656, sl=.02). Scirpus density was generally independent of other water chemistry levels. In one fen Scirpus density declined significantly as Typha density increased (r[sub 2]=25.86). Contamination appears to favor Tvpha invasion, which subsequently leads to displacement of Scirpus.

  2. XL-A A.&lx A!i' X!Ii?Z IL';;i'

    Office of Legacy Management (LM)

    the pemises herein antho,.i:ed tg 2. That an? iuicrjerexce with ' II* tkzrr::Lqp,. to prop+ x>ide,s &&Go? 2f the Dcpnjy,,iE71t 01 ATlily i,lsidCizt to the t*rcrcide o,r, f,f:...

  3. DOE ZERH Case Study: BrightLeaf Homes, McCormick Avenue, Brookfield, IL

    SciTech Connect (OSTI)

    none,

    2015-09-01

    Case study of a DOE 2015 Housing Innovation Award winning production home in the cold climate that got a HERS 38 without PV, with staggered 2x4 studs every 8”on a 2x6 plate with dense-packed R-25 cellulose, basement with 3” XPS exterior and 2: XPS under slab; a vented attic with spray foam top plates and R-60 blown cellulose; 96% AFUE furnace, 14 SEER AC, plus fresh air intake.

  4. EA-1975: LINAC Coherent Light Source-Il, SLAC National Accelerator Laboratory, Menlo Park, California

    Broader source: Energy.gov [DOE]

    DOE prepared an EA on the potential environmental impacts of a proposal to upgrade the existing LINAC Coherent Light Source (LCLS) at the SLAC National Accelerator Laboratory. The proposed LCLS-II would extend the photon energy range, increase control over photon pulses, and enable two-color pump-probe experiments. The X-ray laser beams generated by LCLS-II would enable a new class of experiments: the simultaneous investigation of a material’s electronic and structural properties.

  5. C E N T R A L F IL E S

    Office of Legacy Management (LM)

    ;zJy, y J l . T;? : Tfljj : - ..- ":'cyi:T,;L . . :z*:, 0 , : 7 r;-2 :: '7 .' . A 1 :- :-; '3 s:s:a *;iy,:;. r.3 , :,& . fJ . A . -y& :.-, ;,*3 , J. -. v :+ tn g C E N...

  6. DOE ZERH Case Study: Evolutionary Home Builders, The Adaptation Home, Geneva, IL

    SciTech Connect (OSTI)

    none,

    2015-09-01

    Case study of a DOE 2015 Housing Innovation Award winning custom home in the cold climate that got a HERS 30 without PV, with 2x8 24” on center walls with blown fiberglass and 4” polysio rigid foam; basement with 2” XPS interior, 4” under slab, 4” exterior of foundation wall; vented attic with R-100 blown cellulose; wo air-to-air heat pumps SEER 14.1; HSPF 9.6; heat pump water heater.

  7. 4-27-11-signed-Final-EA-FONSI-for-BeaconPower--IL-PA-.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  8. Airborne gamma-ray spectrometer and magnetometer survey, Belleville quadrangle (IL). Final report

    SciTech Connect (OSTI)

    Not Available

    1981-01-01

    Forty-two uranium anomalies meet the minimum statistical requirements as defined in Volume I. These anomalies are listed and are shown on the Uranium Anomaly Interpretation Map. Potassium (%K), equivalent Uranium (ppM eU), equivalent Thorium (ppM eTh), eU/eTh, eU/K, eTh/K, and magnetic pseudo-contour maps are presented in Appendix E. Stacked Profiles showing geologic strip maps along each flight-line, together with sensor data, and ancillary data are presented in Appendix F. All maps and profiles were prepared on a scale of 1:250,000, but have been reduced to 1:500,000 for presentation in Volume II. Anomalies No. 1, No. 4 to No. 17, No. 22 to No. 23, and No. 27 to No. 30 are over areas underlain by the Radnor Till member (Qti) of the Pleistocene Glasford formation. Anomalies No. 2 and No. 3 are over areas underlain by Pleistocene Cahokia Alluvium (Qc) and the Radnor Till member (Qti) of the Glasford formation. Anomalies No. 18 to No. 21, and No. 24 are over areas underlain by the Pleistocene Equality formation (Qcl). Anomalies No. 25 and No. 26 are over areas underlain by the Equality formation (Qcl) and the Radnor Till member (Qti) of the Glasford formation. Both of these formations are of Pleistocene age. Anomalies No. 31 and No. 33 are over areas underlain by the Pleistocene Cahokia Alluvium (Qc). Anomalies No. 32, No. 34 to No. 38, and No. 40 to No. 42 are over areas underlain by the Radnor Till member (Qti) of the Pleistocene Glasford formation. Anomaly No. 39 is over an area underlain by the Radnor Till (Qti) and the Hagarstown (Qgh) members of the Pleistocene Glasford formation.

  9. Airborne gamma-ray spectrometer and magnetometer survey: Peoria, Decater, Belleville Quadrangles, (IL). Final report

    SciTech Connect (OSTI)

    Not Available

    1981-01-01

    An airborne combined radiometric and magnetic survey was performed for the Department of Energy (DOE) over the area covered by the Peoria, Decatur, and Belleville, 1:250,000 National Topographic Map Series (NTMS), quadrangle maps. The survey was part of DOE's National Uranium Resource Evaluation (NURE) program. Data were collected by a helicopter equipped with a gamma-ray spectrometer with a large crystal volume, and with a high sensitivity proton procession magnetometer. The radiometric system was calibrated at the Walker Field Calibration pads and the Lake Mead Dynamic Test Range. Data quality was ensured during the survey by daily test flights and equipment checks. Radiometric data were corrected for live time, aircraft and equipment background, cosmic background, atmospheric radon, Compton scatter, and altitude dependence. The corrected data were statistically evaluated, plotted, and contoured to produce anomaly maps based on the radiometric response of individual geological units. The anomalies were interpreted and an interpretation map produced. Volume I contains a description of the systems used in the survey, a discussion of the calibration of the systems, the data collection procedures, the data processing procedures, the data presentation, the interpretation rationale, and the interpretation methodology. A separate Volume II for each quadrangle contains the data displays and the interpretation results.

  10. ORNLIRASA-S9Il9 HEALTH m SAFETY RESEARCH DMSION I Environmental...

    Office of Legacy Management (LM)

    ... In 1955 hlallinckrodt Chemical Company, an AEC contractor, used the Heppenstall site for approximately six months to heat, press, and water quench uranium metal. According to ...

  11. Study of requirements and performances of the electromagnetic calorimeter for the Mu2e experiment at Fermilab

    SciTech Connect (OSTI)

    Soleti, S.

    2015-06-15

    In this thesis we discuss the simulation and tests carried out for the optimization and design of the electromagnetic calorimeter for the Mu2e (Muon to electron conversion) experiment, which is a proposed experiment part of the Muon Campus hosted at Fermi National Accelerator Laboratory (FNAL) in Batavia, United States.

  12. Origin State>> CA CA ID ID ID IL KY MD MO NM NM NY NY OH SC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MO NM NM NY NY OH SC TN TN TN, WA, CA TN TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory General Atomics Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Grounds National Security Technologies Sandia National Laboratory Los Alamos National Laboratory Brookhaven National Laboratory CH2M Hill B&W West Valley, LLC Portsmouth Gaseous Diffusion Plant

  13. Origin State>> CA CA ID ID ID IL KY MD NM NM NV NY NY OH TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NM NM NV NY NY OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory General Atomics Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Ground Los Alamos National Laboratory Sandia National Laboratory National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant

  14. Origin State>> CA CA ID ID IL KY NJ NM NY NY NV OH OH OH SC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mix Wastew Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Princeton Plasma Physics Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Demonstration Project National Security Technologies, Inc. Mound Closure Project Portsmouth Gaseous Diffusion Plant Fernald Closure Project Savannah River Site BWXT Y-12 Plant Duratek Nuclear Fuels UT-Battelle Bechtel Jacobs Permafix M&EC EnergX (Foster Wheeler) Pantex Plant SOUTHERN I-15, CA-127,

  15. Origin State>> CA CA ID ID IL KY NJ NM NY NY NV OH OH OH SC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mixed Waste Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Princeton Plasma Physics Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Demonstration Project National Security Technologies, Inc. Mound Closure Project Portsmouth Gaseous Diffusion Plant Fernald Closure Project Savannah River Site BWXT Y-12 Plant Duratek Nuclear Fuels UT-Battelle Bechtel Jacobs Permafix M&EC EnergX (formerly Foster Wheeler) Pantex Plant SOUTHERN I-15,

  16. Origin State>> CA CA ID ID IL KY NJ NM NY NY NV OH OH SC TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SC TN TN TN TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Boeing/Rocketdyne Idaho National Labaratoy Advanced Mixed Waste Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Princeton Plasma Physics Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Demonstration Project National Security Technologies, Inc. Portsmouth Gaseous Diffusion Plant Fernald Closure Project Savannah River Site BWXT Y-12 Plant Duratek

  17. Origin State>> CA ID ID ID IL KY MD NM NM NY NY OH SC TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MD NM NM NY NY OH SC TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Ground Los Alamos National Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Savannah River Site Duratek/Energy Solutions Babcox

  18. Origin State>> CA ID ID ID IL KY NV NY NY OH TN TN TN, WA, CA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NV NY NY OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation

  19. Origin State>> CA ID ID ID IL MD NM NM NV NY NY OH SC TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NV NY NY OH SC TN TN TN, WA, CA TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Aberdeen Proving Ground Sandia National Laboratory Los Alamos National Laboratory National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Savannah River Site Duratek/Energy Solutions Babcox & Wilcox

  20. Origin State>> CA ID ID ID IL MD NM NM NY OH TN TN TN, WA, CA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NY OH TN TN TN, WA, CA TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Aberdeen Proving Ground Sandia National Laboratory Los Alamos National Laboratory Brookhaven National Laboratory Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation (M&EC) Perma-Fix

  1. Origin State>> CA ID ID ID IL NM NM OH TN TN TN, WA, CA TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NM NM OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Sandia National Laboratory Los Alamos National Laboratory Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation (M&EC) Perma-Fix Nuclear Fuels Services Wastren Advantage, Inc.

  2. Natural Gas and Hydrogen Infrastructure Opportunities Workshop, October 18-19, 2011, Argonne National Laboratory, Argonne, IL : Summary Report.

    SciTech Connect (OSTI)

    Kumar, R. comp.; Ahmed, S. comp.

    2012-02-21

    The overall objective of the Workshop was to identify opportunities for accelerating the use of both natural gas (NG) and hydrogen (H{sub 2}) as motor fuels and in stationary power applications. Specific objectives of the Workshop were to: (1) Convene industry and other stakeholders to share current status/state-of-the-art of NG and H{sub 2} infrastructure; (2) Identify key challenges (including non-technical challenges, such as permitting, installation, codes, and standards) preventing or delaying the widespread deployment of NG and H{sub 2} infrastructure. Identify synergies between NG and H{sub 2} fuels; and (3) Identify and prioritize opportunities for addressing the challenges identified above, and determine roles and opportunities for both the government and industry stakeholders. Plenary speakers and panel discussions summarized the current status of the NG and H{sub 2} infrastructure, technology for their use in transportation and stationary applications, and some of the major challenges and opportunities to more widespread use of these fuels. Two break-out sessions of three groups each addressed focus questions on: (1) infrastructure development needs; (2) deployment synergies; (3) natural gas and fuel cell vehicles (NGVs, FCVs), specialty vehicles, and heavy-duty trucks; (4) CHP (combined heat and power), CHHP (combined hydrogen, heat, and power), and synergistic approaches; and (5) alternative uses of natural gas.

  3. New Whole-House Solutions Case Study: Meeting DOE Challenge Home Program Certification - Chicago, IL; Denver, CO; Devens, MA

    SciTech Connect (OSTI)

    2015-01-01

    In this project, three production home builders—K. Hovnanian Homes, David Weekley Homes, and Transformations, Inc.—partnered with Building America team Building Science Corporation to evaluate the certification of five test homes to the new DOE Challenge Home program performance standard (now DOE Zero Energy Ready Home program). The builders identified key benefits and barriers that impacted the certification of the test homes, and the likelihood of whether DOE Challenge Home certification would be pursued in future homes

  4. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    Search Term(s) (supports AND and OR operators and phrase in "double quotes") Register Number Title Abstract Principal Investigator PI Lookup Institution Institution Lookup City Adelaide SA 5001 Aiken Albany Albuquerque Alcoa Center Alexandria Ames Amherst Anchorage Ann Arbor Ardmore Argonne Arlington Asheville Athens Atlanta Auburn Auburn University Augusta Aurora Austin Bailrigg, Lancaster UK, LA1 4Y Baltimore Bar Harbor Batavia Baton Rouge Beaufort Beaverton Belleville Bellevue

  5. Fermi National Accelerator Laboratory FERMILAB-Conf-95/276-E

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fermi National Accelerator Laboratory FERMILAB-Conf-95/276-E CDF and D0 Observation of the Top Quark S.B. Kim Presented for the CDF and D0 Collaborations Fermi National Accelerator Laboratory P.O. Box 500, Batavia, Illinois 60510 Randall Laboratory University of Michigan Ann Arbor, Michigan 48109 August 1995 Published Proceedings from the 15th International Conference on Physics in Collision, Cracow, Poland, June 8-10, 1995 Operated by Universities Research Association Inc. under Contract No.

  6. Iltt: Fermi National Accelerator Laboratory FERMILAB-Pub-75/44-THY

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Iltt: Fermi National Accelerator Laboratory FERMILAB-Pub-75/44-THY June 1975 Weak Interaction Models with New Quarks and Right-Handed Currents" F.A. WILCZEK and A. ZEE t Fermi National Accelerator Laboratory,*Batavia, Illinois 60510 and Joseph Henry Laboratories Princeton University, Princeton, New Jersey 08540 and R. L. KINGSLEY and S. B. TREIMAN Joseph Henry Laboratories Princeton University, Princeton, New Jersey 08540 ABSTRACT We discuss various weak interaction issues for a general

  7. U.S. Department of Energy Awards Contract for Management and Operation of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fermi National Accelerator Laboratory to the Fermi Research Alliance, LLC | Department of Energy Fermi National Accelerator Laboratory to the Fermi Research Alliance, LLC U.S. Department of Energy Awards Contract for Management and Operation of Fermi National Accelerator Laboratory to the Fermi Research Alliance, LLC November 1, 2006 - 9:25am Addthis BATAVIA, ILLINOIS -- The U.S. Department of Energy (DOE) has awarded a new $1.575 billion, five-year contract for management and operation of

  8. EA-1570: Final Environmental Assessment and Finding of No Significant

    Energy Savers [EERE]

    Impact | Department of Energy Assessment and Finding of No Significant Impact EA-1570: Final Environmental Assessment and Finding of No Significant Impact Construction and Operation of Neutrinos at the Main Injector Off-Axis Electron Neutrino Appearance Experiment (NOvA) at the Fermi National Accelerator Laboratory, Batavia, Illinois, and St. Louis County, Minnesota This Environmental Assessment (DOE/EA-1570) provides information and analysis of proposed U.S. Department of Energy activities

  9. EA-1943: Draft Environmental Assessment | Department of Energy

    Energy Savers [EERE]

    Draft Environmental Assessment EA-1943: Draft Environmental Assessment Long Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) at Fermilab, Batavia, Illinois and the Sanford Underground Research Facility, Lead, South Dakota This Draft EA evaluates the environmental impacts of using the existing Main Injector Accelerator at Fermilab to produce a pure beam of muon neutrinos. The neutrinos would be examined at a "near detector" proposed to be constructed at

  10. TeVSymposium12MasterDB (PPD-115151)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Updated 6/6/2012 Tevatron Impact Symposium June 11, 2012 Fermi National Accelerator Laboratory - Batavia, Illinois - USA Registrants List Muons, Inc. 1. Robert Abrams Florida State University 2. Todd Adams Fermi National Accelerator Laboratory 3. Carl Albright Fermi National Accelerator Laboratory 4. Michael Albrow Norrell Design 5. John Altholz Benedictine University 6. Rebecca Alvarez Fermi National Accelerator Laboratory 7. Giorgio Ambrosio INFN, Padova 8. Silvia Amerio Fermi National

  11. Acoustic Building Infiltration Measurement System (ABIMS)

    Broader source: Energy.gov [DOE]

    Lead Performer: Argonne National Laboratory - Lemont, IL Partner: Illinois Institute of Technology - Chicago, IL

  12. Workplace Charging Challenge Partner: Township High School District 214

    Broader source: Energy.gov [DOE]

    Joined the Challenge: October 2014Headquarters: Arlington Heights, ILCharging Locations: Arlington Heights, IL; Buffalo Grove, IL; Elk Grove Village, IL; Mount Prospect, IL; Rolling Meadows, IL;...

  13. Search for techniparticles at D0 Run II

    SciTech Connect (OSTI)

    Feligioni, Lorenzo; /Boston U.

    2006-01-01

    Technicolor theory (TC) accomplishes the necessary electroweak symmetry breaking responsible for the mass of the elementary particles. TC postulates the existence of a new SU(N{sub TC}) gauge theory. Like QCD the exchange of gauge bosons causes the existence of a non-vanishing chiral condensate which dynamically breaks the SU(N{sub TC}){sub L} x SU(N{sub TC}){sub R} symmetry. This gives rise to N{sub TC}{sup 2}-1 Nambu-Goldstone Bosons. Three of these Goldstone Bosons become the longitudinal components of the W{sup {+-}} and Z which therefore acquire mass; the remaining ones are new particles (technihadrons) that can be produced at the high energy colliders and detected. The Technicolor Straw Man Model (TCSM) is a version of the dynamical symmetry breaking with a large number of technifermions and a relative low value of their masses. One of the processes predicted by the TCSM is q{bar q} {yields} V{sub T} {yields} W{pi}{sub T}, where V{sub T} is the Technicolor equivalent of the QCD vector meson and {pi}{sub T} is the equivalent of the pion. W is the electroweak gauge boson of the Standard Model. This dissertation describes the search for W{pi}{sub T} with the D0 detector, a multi-purpose particle detector located at one of the collision points of the Tevatron accelerator situated in Batavia, IL. The final state considered for this thesis is a W boson that decays to electron and neutrino plus a {pi}{sub T} that decays into b{bar c} or b{bar b}, depending on the charge of the initial technivector meson produced. In the D0 detector this process will appear as a narrow cluster of energy deposits in the electromagnetic calorimeter with an associated track reconstructed in the tracking detector. The undetected neutrino from the decay of the W boson will be seen as missing momentum. The fragmentation of the quarks from the decay of the {pi}{sub T} will produce two jets of collimated particles. Events where a b-quark is produced are selected by requesting at least one jet to be associated with a secondary vertex of interaction produced by the decay of B-meson (b-tagging). In the absence of an excess over the Standard Model prediction for the final state considered in this analysis, we compute a 95% Confidence Level upper limit on the techniparticle production cross section for the V{sub T} mass range: 190 GeV/c{sup 2} {le} m(V{sub T} ) {le} 220 GeV/c{sup 2}.

  14. Heat transfer in ocean thermal energy conversion (OTEC) systems. Proceedings of the wanter mnnual Meeting, Chicago, IL, November 16-21, 1980

    SciTech Connect (OSTI)

    Owens, W.L.

    1980-01-01

    Among the topics discussed are: condensation heat transfer on long vertical, axially ridged tubes tests of the Applied Physics Laboratory of Johns Hopkins University (APL/JHU) folded-tube, Ocean Thermal Energy Conversion (OTEC) heat exchanger the design of a 1.0-MW OTEC heat exchanger for ocean testing and convective vaporization and condensation in serrated-fin channels. Also considered are: heat tranfer studies of an improved heat transfer monitor for OTEC an analysis of the mist lift process for mist flow, open-cycle OTEC the heat transfer characteristics of working fluids for OTEC and a comparison of major OTEC power system characteristics.

  15. Instabilities and chaos in quantum optics II; Proceedings of the NATO Advanced Study Institute, Il Ciocco, Italy, June 28-July 7, 1987

    SciTech Connect (OSTI)

    Abraham, N.B.; Arecchi, F.T.; Lugiato, L.A.

    1988-01-01

    The following topics are considered: laser and maser instabilities, classical and quantum noise, transverse effects, dynamics in optical bistability and nonlinear optical media, and methods of analysis in nonlinear dynamics. Particular papers are presented on multistability and chaos in a two-photon microscopic maser, quantum chaos in quantum optics, spatial chaos in bistable optical arrays, four-wave mixing and dynamics, and bifurcation problems in nonlinear optics.

  16. Biogas and alcohol fuels production. Proceedings of the Seminar on Biomass, Energy for City, Farm, and Industry, Chicago, IL, October 25, 26, 1979

    SciTech Connect (OSTI)

    Goldstein, J.

    1980-01-01

    Basic principles of anaerobic digestion are considered along with the status of the Imperial Valley Biogas Project, the Department of Energy program for the recovery of energy and materials from urban waste, the principles of alcohol production from wastes, the mechanical recovery of a refuse-derived cellulosic feedstock for ethanol production, and the production of ethanol from cellulosic biomass. Attention is given to on-farm alcohol fuel production, the current status and future role of gasohol production, methane generation from small scale farms, farmsite installations of energy harvester anaerobic digesters, biogas/composting and landfill recovery, farm-scale composting as an option to anaerobic digestion, designing a high-quality biogas system, and methane as fuel of the future. A description is presented of subjects which are related to landfill gas recovery, biogas purification with permselective membranes, and anaerobic digestion of marine biomass. Other topics studied include the application of biogas technology in India, biogas production in China, biogasification of organic wastes in the Republic of the Philippines, and economics and operational experience of full-scale anaerobic dairy manure digester.

  17. Athletic equipment microbiota are shaped by interactions with...

    Office of Scientific and Technical Information (OSTI)

    Chicago, IL (United States) Argonne National Lab. (ANL), Lemont, IL (United States) MO BIO Lab., Inc., Carlsbad, CA (United States) Argonne National Lab. (ANL), Lemont, IL (United ...

  18. Energy Savings with Acceptable Indoor Air Quality Through Improved Air Flow Control in Residential Retrofit

    Broader source: Energy.gov [DOE]

    Lead Performer: Gas Technology Institute—Des Plaines, IL Partners: -- University of Illinois, Urbana IL -- Midwest Energy Efficiency Alliance, Chicago IL

  19. Fermi National Accelerator Laboratory FERMILAB-Conf-96/099E

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    it Fermi National Accelerator Laboratory FERMILAB-Conf-96/099E CoK)C,. WoO3P73 -- 3 CDF CDF Top Physics G. F. Tartarelli For the CDF Collaboration Fermi National Accelerator Laboratory P.O. Box 500, Batavia, Illinois 60510 I.N.F.N., Sezione di Milano 1-20133 Milano (MI), Italy MASTER May 1996 Proceedings of XXXIst Recontres de Moriond, Electroweak Interactions and Unified Theories, Les Arcs, France, March 16-23, 1996. Operated by Universities Research Association Inc. under Contract No.

  20. ccx204.tmp

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fermi National Accelerator Laboratory FERMILAB-Conf-97/432-E E288 The Discovery of the b Quark at Fermilab in 1977: The Experiment Coordinator's Story John Yoh For the E288 Collaboration Fermi National Accelerator Laboratory P.O. Box 500, Batavia, Illinois 60510 December 1997 Published Proceedings of Twenty Beauti$ul Years of Bottom Physics, IIT, June 29-July 2, 1997 Operated by Universities Research Association Inc. under Contract No. DE-AC02-76CH03000 with the United States Department of

  1. How it works

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How it works MINERvA is a particle physics experiment, located at Fermi National Accelerator Laboratory in Batavia, Illinois. MINERvA was designed to perform high-precision measurements of neutrino interactions on a wide variety of materials, including water, helium, carbon, iron, lead, and plastic. MINERvA is located 100 meters underground, and sits directly in front of the MINOS near detector. The source of MINERvA's neutrino beam is the Neutrinos at the Main Injector beamline, or NuMI. NuMI

  2. Fermilab | Tritium at Fermilab | Steps taken to reduce the amount of

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    tritium Steps taken to reduce the amount of tritium Actions taken in response to the detection of low levels of tritium in surface and sewer water in November 2005 What did we detect in November 2005? In November 2005, for the first time in the then-35-year history of our environmental monitoring program at Fermilab, we detected low levels of tritium in a stream leaving the Fermilab site, and in the sanitary sewers that pump water to the Batavia Wastewater Treatment Plant. The levels

  3. Workplace Charging Challenge Partner: Advocate Health Care

    Broader source: Energy.gov [DOE]

    Joined the Challenge: October 2014Headquarters: Downers Grove, ILCharging Locations: Normal, IL; Oak Lawn, IL; Park Ridge, IL; Downers Grove, IL; Elgin, ILDomestic Employees: 35,000

  4. Langston University - High Energy Physics (LU-HEP)

    SciTech Connect (OSTI)

    Snow, Dr., Joel [Langston Univ., OK (United States)

    2012-08-13

    This final report is presented by Langston University (LU) for the project entitled "Langston University High Energy Physics" (LUHEP) under the direction of principal investigator (PI) and project director Professor Joel Snow. The project encompassed high energy physics research performed at hadron colliders. The PI is a collaborator on the DZero experiment at Fermi National Accelerator Laboratory in Batavia, IL, USA and the ATLAS experiment at CERN in Geneva, Switzerland and was during the entire project period from April 1, 1999 until May 14, 2012. Both experiments seek to understand the fundamental constituents of the physical universe and the forces that govern their interactions. In 1999 as member of the Online Systems group for Run 2 the PI developed a cross-platform Python-based, Graphical User Interface (GUI) application for monitoring and control of EPICS based devices for control room use. This served as a model for other developers to enhance and build on for further monitoring and control tasks written in Python. Subsequently the PI created and developed a cross-platform C++ GUI utilizing a networked client-server paradigm and based on ROOT, the object oriented analysis framework from CERN. The GUI served as a user interface to the Examine tasks running in the D\\O\\ control room which monitored the status and integrity of data taking for Run 2. The PI developed the histogram server/control interface to the GUI client for the EXAMINE processes. The histogram server was built from the ROOT framework and was integrated into the D\\O\\ framework used for online monitoring programs and offline analysis. The PI developed the first implementation of displaying histograms dynamically generated by ROOT in a Web Browser. The PI's work resulted in several talks and papers at international conferences and workshops. The PI established computing software infrastructure at LU and U. Oklahoma (OU) to do analysis of DZero production data and produce simulation data for the experiment. Eventually this included the FNAL SAM data grid system, the SAMGrid (SG) infrastructure, and the Open Science Grid software stacks for computing and storage elements. At the end of 2003 Snow took on the role of global Monte Carlo production coordinator for the D experiment. A role which continues til this day. In January of 2004 Snow started working with the SAMGrid development team to help debug, deploy, and integrate SAMGrid with D Monte Carlo production. Snow installed and configured SG execution and client sites at LUHEP and OUHEP, and a SG scheduler site at LUHEP. The PI developed a python based GUI (DAJ) that acts as a front end for job submission to SAMGrid. The GUI interfaces to the DZero Mone Carlo (MC) request system that uses SAM to manage MC requests by the physics analysis groups. DAJ significantly simplified SG job submission and was deployed in DZero in an effort to increase the user base of SG. The following year was the advent of SAMGrid job submission to the Open Science Grid (OSG) and LHC Computing Grid (LCG) through a forwarding mechanism. The PI oversaw the integration of these grids into the existing production infrastructure. The PI developed an automatic MC (Automc) request processing system capable of operating without user intervention (other than getting grid credentials), and able to submit to any number of sites on various grids. The system manages production at all but 2 sites. The system was deployed at Fermilab and remains operating there today. The PI's work in distributed computing resulted in several talks at international conferences. UTA, OU, and LU were chosen as the collaborating institutions that form the Southwest Tier 2 Center (SWT2) for ATLAS. During the project period the PI contributed to the online and offline software infrastructure through his work with the Run 2 online group, and played a major role in Monte Carlo production for DZero. During the part of the project period in which the PI served as MC production coordinator MC production increased very significantly. In the first year of the PI'

  5. Search for the Standard Model Higgs boson in the decay mode H-> WW-> lnulnu

    SciTech Connect (OSTI)

    Penning, B.; /Freiburg U.

    2009-09-01

    The question of the nature and principles of the universe and our place in it is the driving force of science since Mesopotamian astronomers glanced for the first time at the starry sky and Greek atomism has been formulated. During the last hundred years modern science was able to extend its knowledge tremendously, answering many questions, opening entirely new fields but as well raising many new questions. Particularly Astronomy, Astroparticle Physics and Particle Physics lead the race to answer these fundamental and ancient questions experimentally. Today it is known that matter consists of fermions, the quarks and leptons. Four fundamental forces are acting between these particles, the electromagnetic, the strong, the weak and the gravitational force. These forces are mediated by particles called bosons. Our confirmed knowledge of particle physics is based on these particles and the theory describing their dynamics, the Standard Model of Particles. Many experimental measurements show an excellent agreement between observation and theory but the origin of the particle masses and therefore the electroweak symmetry breaking remains unexplained. The mechanism proposed to solve this issue involves the introduction of a complex doublet of scalar fields which generates the masses of elementary particles via their mutual interactions. This Higgs mechanism also gives rise to a single neutral scalar boson with an unpredicted mass, the Higgs boson. During the last twenty years several experiments have searched for the Higgs boson but so far it escaped direct observation. Nevertheless these studies allow to further constrain its mass range. The last experimental limits on the Higgs mass have been set in 2001 at the LEP collider, an electron positron machine close to Geneva, Switzerland. The lower limit set on the Higgs boson mass is m{sub H} > 114.4 GeV/c{sup 2} and remained for many years the last experimental constraint on the Standard Model Higgs Boson due to the shutdown of the LEP collider and the experimental challenges at hadron machines as the Tevatron. This thesis was performed using data from the D0 detector located at the Fermi National Accelerator Laboratory in Batavia, IL. Final states containing two electrons or a muon and a tau in combination with missing transverse energy were studied to search for the Standard Model Higgs boson, utilizing up to 4.2 fb{sup -1} of integrated luminosity. In 2008 the CDF and D0 experiments in a combined effort were able to reach for the first time at a hadron collider the sensitivity to further constrain the possible Standard Model Higgs boson mass range. The research conducted for this thesis played a pivotal role in this effort. Improved methods for lepton identification, background separation, assessment of systematic uncertainties and new decay channels have been studied, developed and utilized. Along with similar efforts at the CDF experiment these improvements led finally the important result of excluding the presence of a Standard Model Higgs boson in a mass range of m{sub H} = 160-170 GeV/c{sup 2} at 95% Confidence Level. Many of the challenges and methods found in the present analysis will probably in a similar way be ingredients of a Higgs boson evidence or discovery in the near future, either at the Tevatron or more likely at the soon starting Large Hadron Collider (LHC). Continuing to pursue the Higgs boson we are looking forward to many exciting results at the Tevatron and soon at the LHC. In Chapter 2 an introduction to the Standard Model of particle physics and the Higgs mechanism is given, followed by a brief outline of existing theoretical and experimental constraints on the Higgs boson mass before summarizing the Higgs boson production modes. Chapter 3 gives an overview of the experimental setup. This is followed by a description of the reconstruction of the objects produced in proton-antiproton collisions in Chapter 4 and the necessary calorimeter calibrations in Chapter 5. Chapter 6 follows with an explanation of the phenomenology of the proton-antiproton colli

  6. Analysis of natural gases, AL, AR, FL, GA, IL, IN, IA, KY, LA, MD, MI, MS, MO, NJ, NY, NC, OH, PA, TN, VA, and WV; 1951-1991 (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1991-01-01

    The U.S. Bureau of Mines diskette contains analysis and related source data for 2,357 natural gas samples collected from miscellaneous states, which include the following states: Alabama, Arkansas (except Arkoma Basin), Florida, Georgia, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maryland, Michigan, Mississippi, Missouri, New Jersey, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Virginia, and West Virginia. All samples were obtained and analyzed as part of the Bureau's investigations of occurrences of helium in natural gases of countries with free market economies. The survey has been conducted since 1917. The analysis contained on the diskette contain the full range of component analysis data. Five files are on the diskette: READ.ME, MISC.TXT, MISC.DBF, USHEANAL.DBF, and BASINCDE.TXT.

  7. DOE - Office of Legacy Management -- Swenson Evaporator Co -...

    Office of Legacy Management (LM)

    IL.23-1 Evaluation Year: 1987 IL.23-1 Site Operations: Scheduled a raffinate spray drying test that was later cancelled. IL.23-1 Site Disposition: Eliminated - No indication...

  8. Southwestern Power Administration

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    032614 Correspondence between SWPA and 13 members of Congress: Paul Broun, R-GA, Rodney Davis R-IL, John Delaney, D-MD, Jeff Denham R-CA. Robert Dold R-IL, Bill Enyart D-IL, Bill...

  9. ,"Illinois Natural Gas Summary"

    U.S. Energy Information Administration (EIA) Indexed Site

    ...IL3","N3035IL3","N3045IL3" "Date","Natural Gas Citygate Price in Illinois (Dollars per Thousand Cubic Feet)","Illinois Price of Natural Gas Delivered to Residential Consumers (Dollars ...

  10. Measurement of the Three-jet Mass Cross Section in $p\\bar{p}$ Collisions at $\\sqrt{s}=1.96$ TeV

    SciTech Connect (OSTI)

    Hubacek, Zdenek

    2010-06-01

    This thesis describes the measurement of the inclusive three-jet cross section in proton-antiproton collisions at {radical}s = 1.96 TeV measured at the D0 experiment at the Fermilab Tevatron Collider in the Fermi National Accelerator Laboratory, Batavia, Illinois, USA. The cross section as a function of three-jet invariant mass is provided in three regions of the third jet transverse momentum and three regions of jet rapidities. It utilizes a data sample collected in the so called Run IIa data taking period (2002-2006) corresponding to the integrated luminosity of about 0.7 fb{sup -1}. The results are used to test the next-to-leading order predictions of Quantum chromodynamics computed using the latest parton distribution functions.

  11. The soil microbiome influences grapevine-associated microbiota...

    Office of Scientific and Technical Information (OSTI)

    (ANL), Argonne, IL (United States); Univ. of Chicago, Chicago, IL (United States); Marine Biological Lab., Woods Hole, MA (United States); Zhejiang Univ., Hangzhou (China)...

  12. DOE - Office of Legacy Management -- Wyckoff Drawn Steel Co ...

    Office of Legacy Management (LM)

    February 24, 1995 IL.0-09-2 - Metallurgical Laboratory Memorandum; Creutz to Cooper; Subject: Centerless Grinding Equipment; July 28, 1943 IL.0-09-3 - Memorandum...

  13. DOE - Office of Legacy Management -- Max Zuckerman and Sons ...

    Office of Legacy Management (LM)

    - IL 30 FUSRAP Considered Sites Site: MAX ZUCKERMAN & SONS (IL.30 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: 1925...

  14. DOE - Office of Legacy Management -- Armour Research Foundation...

    Office of Legacy Management (LM)

    Research Foundation - IL 17 FUSRAP Considered Sites Site: Armour Research Foundation of the Illinois Institute of Technology (IL.17 ) Eliminated from further consideration under...

  15. DOE - Office of Legacy Management -- American Machine and Metals...

    Office of Legacy Management (LM)

    Metals Inc - IL 24 FUSRAP Considered Sites Site: American Machine and Metals Inc (IL.24 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name:...

  16. EIS-0394: EPA Notice of Availability of the Draft Environmental...

    Broader source: Energy.gov (indexed) [DOE]

    Planning, Design, Construction and Operation a Coal Fueled Electric Power and Hydrogen Gas Production Plant, Four Alternative Sites: Mattoon, IL, Tuscola, IL, Jewett, TX and...

  17. DOE - Office of Legacy Management -- Lindsay Light and Chemical...

    Office of Legacy Management (LM)

    Lindsay Light and Chemical Co - IL 10 FUSRAP Considered Sites Site: LINDSAY LIGHT AND CHEMICAL CO. ( IL.10 ) Eliminated from consideration under FUSRAP Designated Name: Not ...

  18. DOE - Office of Legacy Management -- Era Tool and Engineering...

    Office of Legacy Management (LM)

    Era Tool and Engineering Co - IL 29 FUSRAP Considered Sites Site: Era Tool and Engineering Co. (IL.29 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated...

  19. NETL F 451.1/1-1, Categorical Exclusion Designation Form

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - Grantsburg, IL and Noble, IL FESCCStorage Division Bruce Brown A Nonconventional CO2-EOR Target in the Illinois Basin: Oil Reservoirs of the.. Project planning, data...

  20. DOE - Office of Legacy Management -- W E Pratt Manufacturing...

    Office of Legacy Management (LM)

    E Pratt Manufacturing Co - IL 12 FUSRAP Considered Sites Site: W.E. PRATT MANUFACTURING CO. (IL.12) Eliminated from consideration under FUSRAP Designated Name: Not Designated...

  1. DOE - Office of Legacy Management -- R Krasberg and Sons Manufacturing...

    Office of Legacy Management (LM)

    Krasberg and Sons Manufacturing Co - IL 27 FUSRAP Considered Sites Site: R. KRASBERG AND SONS MANUFACTURING CO. (IL.27) Eliminated from consideration under FUSRAP Designated Name:...

  2. DOE - Office of Legacy Management -- Quality Hardware and Machine...

    Office of Legacy Management (LM)

    FUSRAP Designated Name: Not Designated Alternate Name: Ravenswood Venture Marden Manufacturing Co. IL.11-1 IL.11-2 Location: 58235849 North Ravenswood Avenue , Chicago ,...

  3. DOE - Office of Legacy Management -- Midwest Manufacturing Co...

    Office of Legacy Management (LM)

    Midwest Manufacturing Co - IL 0-04 FUSRAP Considered Sites Site: MIDWEST MANUFACTURING CO (IL.0-04 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated...

  4. Predicting ecological roles in the rhizosphere using metabolome...

    Office of Scientific and Technical Information (OSTI)

    States). Biosciences Div.; Univ. of Chicago, Chicago, IL (United States). Dept. of Bioengineering. Argonne National Lab., Argonne, IL (United States). Biosciences Div. Univ. of...

  5. DOE Zero Energy Ready Home Case Study: Weiss Building & Development...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Weiss Building & Development LLC, System Home, River Forest, IL DOE Zero Energy Ready Home Case Study: Weiss Building & Development LLC, System Home, River Forest, IL Case study of ...

  6. Integrated Biorefineries:Biofuels, Biopower, and Bioproducts...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solazyme, Inc. Peoria, IL Pilot Algae UOP, LLC Kapolei, HI Pilot Thermo - Pyrolysis ZeaChem, Inc. Boardman, OR Pilot Thermo - Pyrolysis Elevance* Boilingbrook, IL...

  7. The structural basis for receptor recognition of human interleukin-18

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Tsutsumi, Naotaka; Kimura, Takeshi; Arita, Kyohei; Ariyoshi, Mariko; Ohnishi, Hidenori; Yamamoto, Takahiro; Zuo, Xiaobing; Maenaka, Katsumi; Park, Enoch Y.; Kondo, Naomi; et al

    2014-12-15

    Interleukin (IL)-18 is a proinflammatory cytokine that belongs to the IL-1 family and plays an important role in inflammation. The uncontrolled release of this cytokine is associated with severe chronic inflammatory disease. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. Here, we present a crystal structure of human IL-18 bound to the two receptor extracellular domains. Generally, the receptors’ recognition mode for IL-18 is similar to IL-1β; however, certain notable differences were observed. The architecture of the IL-18 receptor second domain (D2) is uniquemore » among the other IL-1R family members, which presumably distinguishes them from the IL-1 receptors that exhibit a more promiscuous ligand recognition mode. The structures and associated biochemical and cellular data should aid in developing novel drugs to neutralize IL-8 activity.« less

  8. The structural basis for receptor recognition of human interleukin-18

    SciTech Connect (OSTI)

    Tsutsumi, Naotaka; Kimura, Takeshi; Arita, Kyohei; Ariyoshi, Mariko; Ohnishi, Hidenori; Yamamoto, Takahiro; Zuo, Xiaobing; Maenaka, Katsumi; Park, Enoch Y.; Kondo, Naomi; Shirakawa, Masahiro; Tochio, Hidehito; Kato, Zenichiro

    2014-12-15

    Interleukin (IL)-18 is a proinflammatory cytokine that belongs to the IL-1 family and plays an important role in inflammation. The uncontrolled release of this cytokine is associated with severe chronic inflammatory disease. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. Here, we present a crystal structure of human IL-18 bound to the two receptor extracellular domains. Generally, the receptors’ recognition mode for IL-18 is similar to IL-1β; however, certain notable differences were observed. The architecture of the IL-18 receptor second domain (D2) is unique among the other IL-1R family members, which presumably distinguishes them from the IL-1 receptors that exhibit a more promiscuous ligand recognition mode. The structures and associated biochemical and cellular data should aid in developing novel drugs to neutralize IL-8 activity.

  9. EA-1716: Final Environmental Assessment

    Broader source: Energy.gov [DOE]

    Honeywell International Inc Electric Drive Vehicle Battery and Component Manufacturing Initiative Project Massac County, IL

  10. Building America Best Practices Series: Volume 7.3, Guide to...

    Energy Savers [EERE]

    ... ID Owyhee Cold 5 B ID Payette Cold 5 B ID Power Cold 5 B ID Shoshone Cold 5 B ID Teton ... IL Richland Mixed-Humid 4 A IL Rock Island Cold 5 A IL Saline Mixed-Humid 4 A IL Sangamon ...

  11. --No Title--

    U.S. Energy Information Administration (EIA) Indexed Site

    | (Continued) | ct I | | | | | Year |(Conti-| | | | | | | Month | nued) | | | | | | | ||Average| IL | IN | MI | MN | OH |...

  12. Interaction of interleukin-5 with its receptors on murine leukemic BCL1 cells and its implication in biological activity

    SciTech Connect (OSTI)

    Tsuruoka, N.; Funakoshi, K.; Kodama, S.; Tsujimoto, M. (Suntory Institute for Biomedical Research, Mishima, Osaka (Japan))

    1990-02-01

    Interaction of interleukin (IL)-5 with its receptors on murine leukemic cell line, BCL1 cells was examined. {sup 125}I-labeled recombinant murine IL-5(rmIL-5) bound specifically to high-affinity receptors on BCL1 cells. rmIL-5, which was about 2500-fold more active than recombinant human IL-5(rhIL-5) in IgM-inducing activity on BCL1 cells, also showed about 5000-fold higher affinity to receptors. These results suggest that the bioactivity of IL-5 correlates with its receptor-binding activity. When disulfide bond formation was blocked, rmIL-5 dissociated into a monomer and lost its biological activity. This monomeric form of rmIL-5 also lost its ability to bind to cells, suggesting that dimer formation is essential for the biological activity of IL-5.

  13. DOE - Office of Legacy Management -- Billings Hospital - Small Animal

    Office of Legacy Management (LM)

    Facility - University of Chicago - IL 01 Billings Hospital - Small Animal Facility - University of Chicago - IL 01 FUSRAP Considered Sites Site: Billings Hospital, Small Animal Facility, University of Chicago (IL 01) Eliminated from consideration under FUSRAP due to limited scope of activities and 15 day half-life of P-32 Designated Name: Not Designated Alternate Name: Small Animal Facility, U. of Chicago IL.01-1 Location: University of Chicago , Chicago , Illinois IL.01-1 Evaluation Year:

  14. Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment

    SciTech Connect (OSTI)

    Kim, Jong-Hyuk; Frantz, Aric M.; Anderson, Katie L.; Graef, Ashley J.; Scott, Milcah C.; Robinson, Sally; Sharkey, Leslie C.; O'Brien, Timothy D.; Dickerson, Erin B.; Modiano, Jaime F.

    2014-04-15

    Interleukin-8 (IL-8) gene expression is highly up-regulated in canine hemangiosarcoma (HSA); however, its role in the pathogenesis of this disease is unknown. We investigated the expression of IL-8 in canine HSA tissues and cell lines, as well and the effects of IL-8 on canine HSA in vitro, and in vivo using a mouse xenograft model for the latter. Constitutive expression of IL-8 mRNA, IL-8 protein, and IL-8 receptor were variable among different tumor samples and cell lines, but they showed stable steady states in each cell line. Upon the addition of IL-8, HSA cells showed transient intracellular calcium fluxes, suggesting that their IL-8 receptors are functional and that IL-8 binding activates relevant signaling pathways. Yet, neither addition of exogenous IL-8 nor blockade of endogenous IL-8 by neutralizing anti-IL-8 antibody (α-IL-8 Ab) affected HSA cell proliferation or survival in vitro. To assess potential effects of IL-8 in other tumor constituents, we stratified HSA cell lines and whole tumor samples into “IL-8 high” and “IL-8 low” groups. Genome-wide gene expression profiling showed that samples in the “IL-8 high” tumor group were enriched for genes associated with a “reactive microenvironment,” including activation of coagulation, inflammation, and fibrosis networks. Based on these findings, we hypothesized that the effects of IL-8 on these tumors were mostly indirect, regulating interactions with the microenvironment. This hypothesis was supported by in vivo xenograft experiments where survival and engraftment of tumor cells was inhibited by administration of neutralizing α-IL-8 Ab. Together, our results suggest that IL-8 contributes to establishing a permissive microenvironment during the early stages of tumorigenesis in HSA. - Highlights: • IL-8 is expressed in canine hemangiosarcoma tumor samples and cell lines. • IL-8 transduces a relevant biological signal in canine hemangiosarcoma cells. • IL-8 gene signature is associated with reactive tumor microenvironments. • IL-8 potentiates tumor cell survival and engraftment into host tissues. • Canine hemangiosarcoma provides a unique comparative model for IL-8 studies.

  15. transportation-systems-modeling-training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL TRANSIMS Training Course June 17-19, 2008 School of Civil and Environmental Engineering Atlanta, GA TRANSIMS Training Course April 21-23, 2008 Argonne TRACC West Chicago, IL

  16. DOE Zero Energy Ready Home Case Study: Weiss Building & Development...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    LLC., Custom Home, Downers Grove, IL DOE Zero Energy Ready Home Case Study: Weiss Building & Development LLC., Custom Home, Downers Grove, IL Case study of a DOE Zero Energy Ready ...

  17. RPT_PERIOD","R_S_NAME","LINE_NUM","PROD_CODE","PROD_NAME","PORT...

    U.S. Energy Information Administration (EIA) Indexed Site

    PROCESSOR-IL","IL","ILLINOIS",2 "applicationvnd.ms-excel","ATLANTIC TRADING MARKETING ",7,025,"Crude Oil",3401,"PEMBINA, ND","NORTH DAKOTA",2,260,"CANADA",58,3.14,14,"UNK...

  18. RPT_PERIOD","R_S_NAME","LINE_NUM","PROD_CODE","PROD_NAME","PORT...

    U.S. Energy Information Administration (EIA) Indexed Site

    PROCESSOR-IL","IL","ILLINOIS",2 "applicationvnd.ms-excel","ATLANTIC TRADING MARKETING ",4,025,"Crude Oil",3401,"PEMBINA, ND","NORTH DAKOTA",2,260,"CANADA",1,3.14,14,"UNKN...

  19. DOE - Office of Legacy Management -- International Register ...

    Office of Legacy Management (LM)

    Year: 1987 IL.15-3 Site Operations: Limited testing of centerless grinding techniques for uranium metal for the AEC. IL.15-2 Site Disposition: Eliminated - Potential for...

  20. Workbook Contents

    U.S. Energy Information Administration (EIA) Indexed Site

    Date:","12312015" ,"Next Release Date:","01292016" ,"Excel File Name:","n3050il3m.xls" ,"Available from Web Page:","http:tonto.eia.govdnavnghistn3050il3m.htm"...

  1. Enhanced Gas Absorption in the Ionic Liquid 1-n-Hexyl-3-methylimidazol...

    Office of Scientific and Technical Information (OSTI)

    Journal Article: Enhanced Gas Absorption in the Ionic Liquid 1-n-Hexyl-3-methylimidazolium ... than in the bulk IL at 298-573 K. The solubility for water in the confined and bulk ILs ...

  2. DOE - Office of Legacy Management -- Billings Hospital - Small...

    Office of Legacy Management (LM)

    of Chicago , Chicago , Illinois IL.01-1 Evaluation Year: 1979 IL.01-1 Site Operations: Nature of operations is not clear. Portions of Billings Hospital were reported to have been...

  3. DOE - Office of Legacy Management -- Granite City Army Depot...

    Office of Legacy Management (LM)

    Site was used for storage of GSA thorium residues until circa 1964. IL.0-02-1 Site ... Primary Radioactive Materials Handled: Thorium IL.0-02-1 Radiological Survey(s): None ...

  4. "2014 Retail Power Marketers Sales- Residential"

    U.S. Energy Information Administration (EIA) Indexed Site

    ... Solutions Corp.","IL","Power Marketer",477853,4492034,227638.8,5.0676108 "Green Mountain Energy Company","IL","Power Marketer",24959,190336,16176.4,8.4988652 "Homefield ...

  5. "2014 Retail Power Marketers Sales- Commercial"

    U.S. Energy Information Administration (EIA) Indexed Site

    ... "Glacial Energy Holdings","IL","Power Marketer",2426,128194,8721.1,6.8030485 "Green Mountain Energy Company","IL","Power Marketer",8,7937,443.7,5.5902734 "Homefield ...

  6. Natural Gas Weekly Update

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    In the Midwest, Horizon pipeline received approval to begin construction of a 70-mile pipeline from Joliet, IL north to McHenry, IL. When completed, the project will add...

  7. City of Geneva, Illinois (Utility Company) | Open Energy Information

    Open Energy Info (EERE)

    Geneva Place: Illinois Phone Number: 630-232-1503 Website: www.geneva.il.usindex.aspx?NI Twitter: @CityofGeneva Facebook: https:www.facebook.comgeneva.il Outage Hotline:...

  8. Workbook Contents

    U.S. Energy Information Administration (EIA) Indexed Site

    File Name:","n3020il2m.xls" ,"Available from Web Page:","http:tonto.eia.govdnavnghistn3020il2m.htm" ,"Source:","Energy Information Administration" ,"For Help,...

  9. Workbook Contents

    U.S. Energy Information Administration (EIA) Indexed Site

    File Name:","n3020il4m.xls" ,"Available from Web Page:","http:tonto.eia.govdnavnghistn3020il4m.htm" ,"Source:","Energy Information Administration" ,"For Help,...

  10. Search for: All records | DOE Patents

    Office of Scientific and Technical Information (OSTI)

    Amine, Khalil (Downers Grove, IL) (2) Lu, Jun (2) Lu, Wenquan (2) Park, Sang-Ho (2) Yuan, Shengwen (2) Abouimrane, Ali (1) Baginska, Marta B (1) Belharouak, Ilias (Bolingbrook, IL) ...

  11. Fermilab | Photowalk | 2015 Photowalk: Winning Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    here. Top Three Photos thumb First place photo by Mike Baker, Bolingbrook, IL Hi-res Med-res thumb Second place photo by Mike Baker, Bolingbrook, IL Hi-res Med-res thumb...

  12. Fermilab | Photowalk | 2012 Winning Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    information. Top Five Photos thumb First place photo by Stan Kirschner, Mundelein, IL Hi-res Med-res thumb Second place photo by Brian Schultz, Naperville, IL Hi-res Med-res...

  13. Better Buildings Neighborhood Program Workforce Peer Exchange...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Organizations * Austin, TX * Boulder County, CO * California Center for Sustainable Energy * Charlottesville, VA * Chicago, IL * Energy Efficiency Management * ...

  14. DOE Zero Energy Ready Home Case Study: Evolutionary Home Builders, The

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Adaptation Home, Geneva, IL | Department of Energy Evolutionary Home Builders, The Adaptation Home, Geneva, IL DOE Zero Energy Ready Home Case Study: Evolutionary Home Builders, The Adaptation Home, Geneva, IL DOE Zero Energy Ready Home Case Study: Evolutionary Home Builders, The Adaptation Home, Geneva, IL Case study of a DOE 2015 Housing Innovation Award winning custom home in the cold climate that got a HERS 30 without PV, with 2x8 24" on center walls with blown fiberglass and

  15. Demonstration Assessment of Light-Emitting Diode (LED) Accent Lighting at

    Office of Scientific and Technical Information (OSTI)

    the Field Museum in Chicago, IL (Technical Report) | SciTech Connect Accent Lighting at the Field Museum in Chicago, IL Citation Details In-Document Search Title: Demonstration Assessment of Light-Emitting Diode (LED) Accent Lighting at the Field Museum in Chicago, IL This report reviews a demonstration of light-emitting diode (LED) accent lighting compared to halogen (typical) accent lighting in a gallery of the Field Museum in Chicago, IL. Authors: Myer, Michael ; Kinzey, Bruce R.

  16. computational-fluid-dynamics-training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Table of Contents Date Location Advanced Hydraulic and Aerodynamic Analysis Using CFD March 27-28, 2013 Argonne TRACC Argonne, IL Computational Hydraulics and Aerodynamics using STAR-CCM+ for CFD Analysis March 21-22, 2012 Argonne TRACC Argonne, IL Computational Hydraulics and Aerodynamics using STAR-CCM+ for CFD Analysis March 30-31, 2011 Argonne TRACC Argonne, IL Computational Hydraulics for Transportation Workshop September 23-24, 2009 Argonne TRACC West Chicago, IL

  17. Construction Safety Advisory Committee, Meeting Minutes- May 23, 2002

    Broader source: Energy.gov [DOE]

    Description of CSAC agenda activities during CSAC meeting in Chicago, IL. The meeting was held on May 23, 2002.

  18. Gas Technology Institute (Partnership for Advanced Residential...

    Open Energy Info (EERE)

    Technology Institute (Partnership for Advanced Residential Retrofit) Jump to: navigation, search Name: Gas Technology Institute Place: Des Plaines, IL Website:...

  19. Utilization Technology Institute | Open Energy Information

    Open Energy Info (EERE)

    Utilization Technology Institute Jump to: navigation, search Name: Utilization Technology Institute Place: Des Plaines, IL References: Utilization Technology Institute1...

  20. The depletion of Interleukin-8 causes cell cycle arrest and increases the efficacy of docetaxel in breast cancer cells

    SciTech Connect (OSTI)

    Shao, Nan; Chen, Liu-Hua; Ye, Run-Yi; Lin, Ying; Wang, Shen-Ming

    2013-02-15

    Highlights: ? IL-8 depletion affects cell cycle distribution. ? Intrinsic IL-8 mediates breast cancer cell migration and invasion. ? IL-8 siRNA down regulates key factors that control survival and metastatic pathway. ? IL-8 depletion reduces integrin ?3 expression. ? IL-8 depletion increases the chemosensitivity to docetaxel. -- Abstract: IL-8 is a multi-functional pro-inflammatory chemokine, which is highly expressed in cancers, such as ER-negative breast cancer. The present study demonstrates the pervasive role of IL-8 in the malignant progression of ER-negative breast cancer. IL-8 siRNA inhibited proliferation and delayed the G1 to S cell cycle progression in MDA-MB-231 and BT549 cells. IL-8 silencing resulted in the upregulation of the CDK inhibitor p27, the downregulation of cyclin D1, and the reduction of phosphorylated-Akt and NF-?B activities. IL-8 depletion also increased the chemosensitivity to docetaxel. These results indicate a role for IL-8 in promoting tumor cell survival and resistance to docetaxel and highlight the potential therapeutic significance of IL-8 depletion in ER-negative breast cancer patients.

  1. 2014 Retail Power Marketers Sales- Commercial

    U.S. Energy Information Administration (EIA) Indexed Site

    ... 6.03 Glacial Energy Holdings IL Power Marketer 2,426 128,194 8,721.1 6.80 Green Mountain Energy Company IL Power Marketer 8 7,937 443.7 5.59 Homefield Energy IL Power Marketer ...

  2. Regulation of the human interleukin-2/interleukin-2 receptor system: A role for immunosuppression

    SciTech Connect (OSTI)

    Kaempfer, R.

    1994-12-31

    The strength of the cellular immune response is regulated to a large extent by the amount of interleukin-2 (IL-2) produced in response to a stimulus. The ability of lymphocytes and other cells to respond to IL-2 depends upon the expression of cell surface IL-2 receptors. Formation of a high-affinity IL-2 receptor is regulated primarily through induction of its {alpha} subunit, IL-2R{alpha}. Once formed, the IL-2R{alpha} chain turns over rapidly, rendering expression of high-affinity IL-2 receptors during the immune response dependent upon continuous activity of the IL-2R{alpha} gene. The induced expression of both human IL-2 and IL-2R{alpha} chains is sensitive to cell-mediated suppression by CD8 cells; depletion of CD8 cells leads to extensive superinduction. This coupled suppression of IL-2 and IL-2R{alpha} genes greatly increases the extend of control, and strongly limits the strength, of the signal transduced by this ligand/receptor system during an immune response. 29 refs., 3 figs.

  3. Proposed Fermilab fixed target experiment: Kaons at the Tevatron. Environmental Assessment

    SciTech Connect (OSTI)

    Not Available

    1993-12-01

    The US Department of Energy (DOE) has prepared an Environmental Assessment (EA), DOE/EA-0898, evaluating the impacts associated with the proposed fixed target experiment at the Fermi National Accelerator Laboratory (Femilab) in Batavia, Illinois, known as Kaons at the Tevatron (KTeV). The proposed KTeV project includes reconfiguration of an existing target station, enhancement of an existing beam transport system connected to existing utility facilities, and construction of a new experimental detector hall area. The study of the K meson, a type of subatomic particle, has been going on at Fermilab for 20 years. The proposed KTEV project advances the search for the origins of a violation of a fundamental symmetry of nature called charge parity (CP) violation. Based on the analysis in the EA, the DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement is not required.

  4. Interleukin 6 promotes endometrial cancer growth through an autocrine feedback loop involving ERKNF-?B signaling pathway

    SciTech Connect (OSTI)

    Che, Qi; Liu, Bin-Ya; Wang, Fang-Yuan; He, Yin-Yan; Lu, Wen; Liao, Yun; Gu, Wei; Wan, Xiao-Ping

    2014-03-28

    Highlights: IL-6 could promote endometrial cancer cells proliferation. IL-6 promotes its own production through an autocrine feedback loop. ERK and NF-?B pathway inhibitors inhibit IL-6 production and tumor growth. IL-6 secretion relies on the activation of ERKNF-?B pathway axis. An orthotopic nude endometrial carcinoma model confirms the effect of IL-6. - Abstract: Interleukin (IL)-6 as an inflammation factor, has been proved to promote cancer proliferation in several human cancers. However, its role in endometrial cancer has not been studied clearly. Previously, we demonstrated that IL-6 promoted endometrial cancer progression through local estrogen biosynthesis. In this study, we proved that IL-6 could directly stimulate endometrial cancer cells proliferation and an autocrine feedback loop increased its production even after the withdrawal of IL-6 from the medium. Next, we analyzed the mechanism underlying IL-6 production in the feedback loop and found that its production and IL-6-stimulated cell proliferation were effectively blocked by pharmacologic inhibitors of nuclear factor-kappa B (NF-?B) and extra-cellular signal-regulated kinase (ERK). Importantly, activation of ERK was upstream of the NF-?B pathways, revealing the hierarchy of this event. Finally, we used an orthotopic nude endometrial carcinoma model to confirm the effects of IL-6 on the tumor progression. Taken together, these data indicate that IL-6 promotes endometrial carcinoma growth through an expanded autocrine regulatory loop and implicate the ERKNF-?B pathway as a critical mediator of IL-6 production, implying IL-6 to be an important therapeutic target in endometrial carcinoma.

  5. Ionic Liquid–Solute Interactions Studied by 2D NOE NMR Spectroscopy

    SciTech Connect (OSTI)

    Khatun, Sufia; Castner, Edward W.

    2014-11-26

    Intermolecular interactions between a Ru²⁺(bpy)₃ solute and the anions and cations of four different ionic liquids (ILs) are investigated by 2D NMR nuclear Overhauser effect (NOE) techniques, including {¹H-¹⁹F} HOESY and {¹H-¹H} ROESY. Four ILs are studied, each having the same bis(trifluoromethylsulfonyl)amide anion in common. Two of the ILs have aliphatic 1-alkyl-1-methylpyrrolidinium cations, while the other two ILs have aromatic 1-alkyl-3-methylimidazolium cations. ILs with both shorter (butyl) and longer (octyl or decyl) cationic alkyl substituents are studied. NOE NMR results suggest that the local environment of IL anions and cations near the Ru²⁺(bpy)₃ solute is rather different from the bulk IL structure. The solute-anion and solute-cation interactions are significantly different both for ILs with short vs long alkyl tails and for ILs with aliphatic vs aromatic cation polar head groups. In particular, the solute-anion interactions are observed to be about 3 times stronger for the cations with shorter alkyl tails relative to the ILs with longer alkyl tails. The Ru²⁺(bpy)₃ solute interacts with both the polar head and the nonpolar tail groups of the 1- butyl-1-methylpyrrolidinium cation but only with the nonpolar tail groups of the 1-decyl-1-methylpyrrolidinium cation.

  6. Ionic Liquid–Solute Interactions Studied by 2D NOE NMR Spectroscopy

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Khatun, Sufia; Castner, Edward W.

    2014-11-26

    Intermolecular interactions between a Ru²⁺(bpy)₃ solute and the anions and cations of four different ionic liquids (ILs) are investigated by 2D NMR nuclear Overhauser effect (NOE) techniques, including {¹H-¹⁹F} HOESY and {¹H-¹H} ROESY. Four ILs are studied, each having the same bis(trifluoromethylsulfonyl)amide anion in common. Two of the ILs have aliphatic 1-alkyl-1-methylpyrrolidinium cations, while the other two ILs have aromatic 1-alkyl-3-methylimidazolium cations. ILs with both shorter (butyl) and longer (octyl or decyl) cationic alkyl substituents are studied. NOE NMR results suggest that the local environment of IL anions and cations near the Ru²⁺(bpy)₃ solute is rather different from the bulkmore » IL structure. The solute-anion and solute-cation interactions are significantly different both for ILs with short vs long alkyl tails and for ILs with aliphatic vs aromatic cation polar head groups. In particular, the solute-anion interactions are observed to be about 3 times stronger for the cations with shorter alkyl tails relative to the ILs with longer alkyl tails. The Ru²⁺(bpy)₃ solute interacts with both the polar head and the nonpolar tail groups of the 1- butyl-1-methylpyrrolidinium cation but only with the nonpolar tail groups of the 1-decyl-1-methylpyrrolidinium cation.« less

  7. Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro

    SciTech Connect (OSTI)

    Rubin, L.A.; Kurman, C.C.; Fritz, M.E.; Biddison, W.E.; Boutin, B.; Yarchoan, R.; Nelson, D.L.

    1985-11-01

    With the use of an enzyme-linked immunoabsorbent assay to measure soluble human interleukin 2 receptors (IL 2R), certain human T cell leukemia virus I (HTLV I)-positive T cell lines were found to spontaneously release large quantities of IL 2R into culture supernatants. This was not found with HTLV I-negative and IL 2 independent T cell lines, and only one of seven B cell-derived lines examined produced small amounts of IL 2R. In addition to this constitutive production of soluble IL 2R by certain cell lines, normal human peripheral blood mononuclear cells (PBMC) could be induced to release soluble IL 2R by plant lectins, the murine monoclonal antibody OKT3, tetanus toxoid, and allogeneic cells. Such activated cells also expressed cellular IL 2R measurable in detergent solubilized cell extracts. The generation of cellular and supernatant IL 2R was: dependent on cellular activation, rapid, radioresistant (3000 rad), and inhibited by cycloheximide treatment. NaDodSO4-polyacrylamide gel electrophoresis analysis of soluble IL 2R demonstrated molecules of apparent Mr = 35,000 to 40,000, and 45,000 to 50,000, respectively, somewhat smaller than the mature surface receptor on these cells. The release of soluble IL 2R appears to be a characteristic marker of T lymphocyte activation and might serve an immunoregulatory function during both normal and abnormal cell growth and differentiation.

  8. Human interleukin 2 receptor. beta. -chain gene: Chromosomal localization and identification of 5 prime regulatory sequences

    SciTech Connect (OSTI)

    Gnarra, J.R.; Otani, Hiroki; Wang, M.G.; McBride, O.W.; Sharon, M.; Leonard, W.J. )

    1990-05-01

    Interleukin 2 (IL-2) binds to and stimulates activated T cells through high-affinity IL-2 receptors (IL-2Rs). Such receptors represent a complex consisting of at least two proteins, the 55-kDa IL-2R{alpha} chain and the 70-kDa IL-2R{beta} chain. The low-affinity, IL-2R{alpha} chain cannot by itself transduce a mitogenic signal, whereas IL-2 stimulates resting lymphocytes through the intermediate-affinity, IL-2R{beta} receptor. The authors report here identification of the genomic locus for IL-2R{beta}. The exons are contained on four EcoRI fragments of 1.1, 9.2, 7.2, and 13.7 kilobases. The 1.1-kilobase EcoRI fragment lies at the 5{prime}-most end of the genomic locus and contains promoter sequences. The promoter contains no TATA box-like elements but does contain the d(GT){sub n} class of middle repetitive elements, which may play an interesting regulatory role. The IL-2R{beta} gene is localized to chromosome 22q11.2-q12, a region that is the locus for several lymphoid neoplasias.

  9. Molecular mechanisms of ionic liquid cytotoxicity probed by an integrated experimental and computational approach

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Yoo, Brian; Jing, Benxin; Jones, Stuart E.; Lamberti, Gary A.; Zhu, Yingxi; Shah, Jindal K.; Maginn, Edward J.

    2016-02-02

    Ionic liquids (ILs) are salts that remain liquid down to low temperatures, and sometimes well below room temperature. ILs have been called “green solvents” because of their extraordinarily low vapor pressure and excellent solvation power, but ecotoxicology studies have shown that some ILs exhibit greater toxicity than traditional solvents. A fundamental understanding of the molecular mechanisms responsible for IL toxicity remains elusive. Here we show that one mode of IL toxicity on unicellular organisms is driven by swelling of the cell membrane. Cytotoxicity assays, confocal laser scanning microscopy, and molecular simulations reveal that IL cations nucleate morphological defects in themore » microbial cell membrane at concentrations near the half maximal effective concentration (EC50) of several microorganisms. Lastly, cytotoxicity increases with increasing alkyl chain length of the cation due to the ability of the longer alkyl chain to more easily embed in, and ultimately disrupt, the cell membrane.« less

  10. Workplace Charging Challenge Partner: Lewis & Clark Community College |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Community College Workplace Charging Challenge Partner: Lewis & Clark Community College Workplace Charging Challenge Partner: Lewis & Clark Community College Joined the Challenge: June 2014 Headquarters: Godfrey, IL Charging Locations: Godfrey, IL; Alton, IL Domestic Employees: 663 Lewis & Clark Community College is committed to reaching campus carbon neutrality by 2058. The single largest hurdle to overcome in meeting this goal is reducing commuter

  11. Workplace Charging Challenge Partner: Schneider Electric | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Schneider Electric Workplace Charging Challenge Partner: Schneider Electric Workplace Charging Challenge Partner: Schneider Electric Joined the Challenge: March 2013 Headquarters: Palatine, IL Charging Locations: Cedar Rapids, IA; Palatine, IL; O'Fallon, MO; Des Plaines, IL; Knightdale, NC; West Kingston, RI; North Andover, MA; Billerica, MA; Nashville, TN; LaVergne, TN; Smryna, TN; Clovis, CA; Costa Mesa, CA; Carrollton, TX; Seneca, SC; Lexington, KY; Detroit, MI Domestic Employees:

  12. Antigen-specific murine T cell clones produce soluble interleukin 2 receptor on stimulation with specific antigens

    SciTech Connect (OSTI)

    Wagner, D.K.; York-Jolley, J.; Malek, T.R.; Berzofsky, J.A.; Nelson, D.L.

    1986-07-15

    In this study, monoclonal antibodies were used to the murine IL 2 receptor (IL 2R) termed 3C7 and 7D4, which bind to different epitopes on the murine IL 2R, to develop an ELISA to measure soluble murine IL 2R. Surprisingly, stimulated murine spleen cells not only expressed cell-associated IL 2R, but also produced a considerable level of cellfree IL 2R in the culture supernatant fluid. To assess the fine specificity of this response, myoglobin-immune murine T cell clones were stimulated with appropriate or inappropriate antigen and syngeneic or allogeneic presenting cells. Proliferation, measured by (/sup 3/H) thymidine incorporation, and levels of soluble IL 2R were determined at day 4. The production of soluble IL2R displayed the same epitope fine specificity, genetic restriction, and antigen dose-response as the proliferative response. Indeed, in some cases there was sharper discrimination of epitope specificity and genetic restriction with the soluble IL 2R levels. There was also reproducible clone-to-clone variation in the amount of soluble receptor produced in response to antigen among 12 T cell clones and lines tested. In time course experiments, proliferation was greatest at day 3, whereas soluble IL 2R levels continued to rise in subsequent days. To the authors' knowledge, this is the first demonstration of release of secretion of soluble IL 2R by murine T cells, and the first demonstration of the fine specificity and genetic restriction of the induction of soluble IL 2R by specific antigen.

  13. Environmental assessment -- Proposed neutrino beams at the Main Injector project

    SciTech Connect (OSTI)

    1997-12-01

    The US Department of Energy (DOE) proposes to build a beamline on the Fermi National Accelerator Laboratory (Fermilab) site to accommodate an experimental research program in neutrino physics. The proposed action, called Neutrino Beams at the Main Injector (NuMI), is to design, construct, operate and decommission a facility for producing and studying a high flux beam of neutrinos in the energy range of 1 to 40 GeV (1 GeV is one billion or 10{sup 9} electron volts). The proposed facility would initially be dedicated to two experiments, COSMOS (Cosmologically Significant Mass Oscillations) and MINOS (Main Injector Neutrino Oscillation Search). The neutrino beam would pass underground from Fermilab to northern Minnesota. A tunnel would not be built in this intervening region because the neutrinos easily pass through the earth, not interacting, similar to the way that light passes through a pane of glass. The beam is pointed towards the MINOS detector in the Soudan Underground Laboratory in Minnesota. Thus, the proposed project also includes construction, operation and decommissioning of the facility located in the Soudan Underground Laboratory in Minnesota that houses this MINOS detector. This environmental assessment (EA) has been prepared by the US Department of Energy (DOE) in accordance with the DOE`s National Environmental Policy Act (NEPA) Implementing Procedures (10 CFR 1021). This EA documents DOE`s evaluation of potential environmental impacts associated with the proposed construction and operation of NuMI at Fermilab and its far detector facility located in the Soudan Underground Laboratory in Minnesota. Any future use of the facilities on the Fermilab site would require the administrative approval of the Director of Fermilab and would undergo a separate NEPA review. Fermilab is a Federal high-energy physics research laboratory in Batavia, Illinois operated on behalf of the DOE by Universities Research Association, Inc.

  14. Ira Goldberg | Argonne Leadership Computing Facility

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    Ira Goldberg Finance Ira Goldberg Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2133 Argonne, IL 60439 630-252-8500 i...

  15. Search for: All records | SciTech Connect

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    Photon Source, Argonne, IL (United States) Atlanta Regional Office, Atlanta, GA (United States) Atmospheric System Research Bartlesville Project Office, OK (United ...

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  17. Other Participants 2000 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Lake South High School , Crystal Lake , IL Dulles High School , Sugar Land , TX DuPont Manual Magnet High School , Louisville , KY East Brunswick High School , East ...

  18. Mirek Suliba | Argonne Leadership Computing Facility

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    Mirek Suliba HPC Systems Administration Specialist Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Rm. 1121 Argonne, IL 60439 630-252-xxxx msuliba

  19. EA-1975: Final Environmental Assessment | Department of Energy

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    Final Environmental Assessment EA-1975: Final Environmental Assessment Linac Coherent Light Source-IL, SLAC National Accelerator Laboratory, Menlo Park, California DOE issued a ...

  20. Thomas J. Howe | Argonne Leadership Computing Facility

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    J. Howe Project Manager Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 3D18 Argonne, IL 60439 630-252-1861 tjhowe

  1. Revenue from Sales to Ultimate Customers (Thousand Dollars) by...

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    ... Service",0,5,1819,0,"NA",1824 2005,"IL","Delivery-Only ...ustry",8201199,5179341,3963869,"NA",898636,18243045 1999,"UT","Total Electric ...

  2. Better Buildings Residential Network Data & Evaluation Peer Exchange...

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    Cadmus Group Chicago, IL Civic Works (Baltimore, MD) Clean Energy Durham CORE DC Sustainable Energy Utility Eagle County, CO Efficiency Vermont Energize New York Greater ...

  3. Technical Sessions F. J. Barnes W. Porch and D. Cooper Los Alamos...

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    K. E. Kunkel Illinois State Water Survey Champaign, IL L. Hipps Utah State University Logan, UT The lower boundary of the GCM (general circulation model) modeling domain, the...

  4. Rail Splitter Wind Farm | Open Energy Information

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    Wind Facility Status In Service Owner Horizon Developer Horizon Location Tazewell and Logan Counties IL Coordinates 40.309398, -89.396195 Show Map Loading map......

  5. Scientific Advisory Committee | Argonne National Laboratory

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    David Awschalom Liew Family Profesor in Spintronics and Quantum Information Institute for Molecular Engineering The University of Chicago 5640 S. Ellis Avenue, ERC 237 Chicago, IL ...

  6. Technical Meeting: Physical Characterization of Connected Buildings Equipment

    Broader source: Energy.gov [DOE]

    On January 28-29, 2015, BTO hosted a technical meeting on the Physical Characterization of Connected Buildings Equipment in Chicago, IL.

  7. Exploiting Network Parallelism

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    for Science Department, Lawrence Berkeley National Laboratory, Berkeley, CA Mathematics and Computer Science Division, Argonne National Laboratory Argonne, IL School of ...

  8. Preeti Malakar | Argonne Leadership Computing Facility

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    Preeti Malakar Postdoctoral Appointee - Data Centric Preeti Malakar Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 4E16 Argonne, IL 60439 630-252-3039...

  9. Kevin Harms | Argonne Leadership Computing Facility

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    Kevin Harms Senior Software Developer Kevin Harms Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 1129 Argonne, IL 60439 630-252-3398 harms...

  10. Jini Ramprakash | Argonne Leadership Computing Facility

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    Jini Ramprakash User Experience Specialist Team Lead Jini Ramprakash Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2132 Argonne, IL 60439 630-252-1781...

  11. Janet Jaseckas | Argonne Leadership Computing Facility

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    Jaseckas User Experience Specialist Janet Jaseckas Argonne National Laboratory 9700 S. Cass Avenue Building 240 Rm. 2134 Argonne, IL 60439 630-252-3422 jaseckas@anl...

  12. Robert Scott | Argonne Leadership Computing Facility

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    Robert Scott Technical Support Analyst Robert Scott Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 2D15 Argonne, IL 60439 630-252-5745 scott...

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    Kathy DiBennardi Executive Secretary Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 4D11 Argonne IL, 60439 630-252-8600 dibennar...

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    Rich Software Development Specialist Paul Rich Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3126 Argonne, IL 60439 630-252-2430 richp@alcf.anl...

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    Katrina Errant Floor Manager Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 3D18 Argonne, IL 60439 630-252-0024 kerrant...

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    Knowles Principal Software Development Specialist Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3121 Argonne, IL 60439 630-252-6342 jknowles@alcf.anl...

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    Piotr Zbiegiel Senior Cyber Security Engineer Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2122 Argonne, IL 60439 630-252-2939 pzbiegiel@anl...

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    Hal Finkel Assistant Computational Scientist Hal Finkel Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2126 Argonne, IL 60439 630-252-0023 hfinkel...

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    Gordon McPheeters HPC Systems Administration Specialist - File Systems Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Rm. 1122 Argonne, IL 60439 630-252-6430...

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    Khairi Reda Argonne Scholar Khairi Reda Argonne National Laboratory 9700 S. Cass Avenue Building 240 Rm. 5138 Argonne, IL 60439 630-252-3678 kreda...

  1. Hyeondeok Shin | Argonne Leadership Computing Facility

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    Hyeondeok Shin Postdoctoral Appointee Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 2C7 Argonne, IL 60439 630-252-7993 hshin...

  2. Margaret Kaczmarski | Argonne Leadership Computing Facility

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    Margaret Kaczmarski User Experience Administrator Margaret Kaczmarski Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 2D25 Argonne IL, 60439 630-252-0958...

  3. Michael Zhang | Argonne Leadership Computing Facility

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    Zhang Software Developer Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 3D29 Argonne, IL 60439 zhangm@anl.gov...

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    IL (United States) Clinch River Breeder Reactor Project, Oak Ridge, TN (United States) ... Have feedback or suggestions for a way to improve these results? Fusion Peptides Promote ...

  6. City of Geneseo | Open Energy Information

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    Type Community Wind Facility Status In Service Owner City of Geneseo Developer Johnson Controls City of Geneseo Location Geneseo IL Coordinates 41.42597968,...

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  8. Postdoctoral Research Awards Annual Research Meeting: Joseph...

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    Farha and Joseph T. Hupp Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 * Molecular ...

  9. EERE PROJECT MANAGEMENT CENTER Nl!PA DFTFnIINATION RECIPIENT...

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    Il.II.': , u.s. DEPARTMENT OFFNERGY EERE PROJECT MANAGEMENT CENTER NlPA DFTFnIINATION ... publication, and distribution: and classroom training and informational programs), ...

  10. Grant F. Wood | Argonne Leadership Computing Facility

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    Grant F. Wood Consultant - Project Management 9700 S. Cass Avenue Building 240 Wkstn. 3D18 Argonne, IL 60439 630-252-5315 gfwood

  11. Characteristics of Lamellar Mesophases in Strongly Segregated...

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    Argonne, IL (US) Sponsoring Org: NSFUNIVERSITY Country of Publication: United States Language: ENGLISH Word Cloud More Like This Full Text Journal Articles DOI: 10.1021ma5006233...

  12. Nicotinamide mononucleotide adenylyltransferase displays alternate...

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  13. MEEA Midwest Energy Solutions Conference

    Broader source: Energy.gov [DOE]

    Midwest Energy Efficiency Alliance (MEEA) is hosting its annual conference at the Chicago Hilton and Towers in Chicago, IL, on Jan. 28-30, 2015.

  14. OPSI Annual Meeting

    Broader source: Energy.gov [DOE]

    The Organization of PJM States, Inc. (OPSI) is hosting its annual meeting in Chicago, IL, on October 13-14, 2014.

  15. APS 2007 Conferences

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    Accelerator Conference (APAC 2007) (Jan. 29-Feb. 2) Indore, India APS Upgrade ERL Optics Workshop (April 23) Argonne National Laboratory, Argonne, IL Synchrotron Radiation...

  16. Conferences and Workshops | Advanced Photon Source

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    Laboratory, Argonne, IL May 17-21 Conference on Advanced Phase Measurement Methods in Optics and Imaging, with Special Sessions for X-ray Methods Monte Verita, Locarno,...

  17. Center Ethanol Company LLC | Open Energy Information

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    LLC Jump to: navigation, search Name: Center Ethanol Company LLC Place: Illinois Product: Illinois based company building a 54m gallon ethanol plant in Sauget, IL. References:...

  18. Joseph A. Insley | Argonne Leadership Computing Facility

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    Joseph A. Insley Principal Software Development Specialist Joe Insley Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 4140 Argonne, IL 60439 630-252-5649...

  19. ECOR VAP Flux Corrections, Gap-filling, and Results David R....

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    ECOR VAP Flux Corrections, Gap-filling, and Results David R. Cook, Meredith Franklin, Donna J. Holdridge Argonne National Laboratory, Argonne, IL This work was supported by the...

  20. Structural and functional adaptation of vancomycin resistance...

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    6; Journal Issue: 4; Journal ID: ISSN 2150-7511 Publisher: American Society for Microbiology Research Org: Argonne National Laboratory (ANL), Argonne, IL (United States)...

  1. Lensless Imaging of Atomic Surface Structures via Ptychography...

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    Materials Science Division, Argonne National Laboratory, Argonne, IL Coherent x-ray diffraction imaging (CDI) is a lensless technique, which has been in rapid progress recently...

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    Joe Sortino Research Aide - VIZ Team Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 4E7 Argonne, IL 60439 jsortino@anl...

  3. Jie Jiang | Argonne Leadership Computing Facility

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    Jie Jiang Research Aide - VIZ Team Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 4E9A Argonne, IL 60439 jiejiang@anl...

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    Scullin HPC Systems Administration Specialist Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3122 Argonne, IL 60439 630-252-6412 wscullin...

  5. Adam Young | Argonne Leadership Computing Facility

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    Young Guest Researcher Argonne National Laboratory 9700 S. Cass Avenue Building 240 Wkstn. 4D15 Argonne, IL 60439 younga@anl...

  6. Towards a Large-Scale Recording System: Demonstration of Polymer...

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    Resource Relation: Conference: Presented at: 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, United States, Aug 26 - Aug ...

  7. National Association of the Remodeling Industry (NARI) | Open...

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    ... New Brunswick Laboratory (NBL), Argonne, IL (United ... In this presentation, I will review the status of the proton ... The Recoil Polarization Experiments at Jefferson Lab ...

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    ... New Brunswick Laboratory (NBL), Argonne, IL (United ... This paper presents a review on the field of inclusive ... in quasi-elastic kinematics in Hall A at Jefferson Lab. ...

  10. Chicago Climate Action Plan | Open Energy Information

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    Low emission development planning Resource Type Case studiesexamples Availability Free Website http:www.chicagoclimateactio Locality Chicago, IL References Chicago Climate...

  11. DOE Zero Energy Ready Home Case Study: BrightLeaf Homes, McCormick Avenue,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brookfield, IL | Department of Energy BrightLeaf Homes, McCormick Avenue, Brookfield, IL DOE Zero Energy Ready Home Case Study: BrightLeaf Homes, McCormick Avenue, Brookfield, IL DOE Zero Energy Ready Home Case Study: BrightLeaf Homes, McCormick Avenue, Brookfield, IL Case study of a DOE 2015 Housing Innovation Award winning production home in the cold climate that got a HERS 38 without PV, with staggered 2x4 studs every 8"on a 2x6 plate with dense-packed R-25 cellulose, basement with

  12. DOE Zero Energy Ready Home Case Study: StreetScape Development, LLC,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Libertyville, IL, Custom | Department of Energy StreetScape Development, LLC, Libertyville, IL, Custom DOE Zero Energy Ready Home Case Study: StreetScape Development, LLC, Libertyville, IL, Custom Case study of a DOE Zero Energy Ready Home in Libertyville, IL, that scored HERS 45 without PV. This 2,763-square-foot custom home has advanced framed walls with R-20 of open-cell spray foam, R-49 open-cell spray-foam sealed attic, an HRV, and a tankless water heater for hydro coil furnace with

  13. Diane Rodi | Argonne Leadership Computing Facility

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    Diane Rodi ALD ESH/QA Coordinator Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Rm. 4125 Argonne, IL 60439 630-252-1617 drodi@anl

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    Douglas Waldron Senior Data Architect Douglas Waldron Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3120 Argonne, IL 60439 630-252-2884 dwaldron

  15. Ed Holohan | Argonne Leadership Computing Facility

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    Ed Holohan Principal HPC Network Administration Specialist Ed Holohan Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2121 Argonne, IL 60439 630-252-6094 eholohan

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    Pershey Principal Software Development Specialist Eric Pershey Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3123 Argonne, IL 60439 630-252-5744 pershey

  17. Molecular design for growth of supramolecular membranes with...

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    Research Org: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US) Sponsoring Org: DOE - BASIC ENERGY SCIENCES Country of Publication: United States ...

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    on Shock Compression of Condensed Matter held June 26 - July 1, 2011 in Chicago, IL.; Related Information: Proposed for presentation at the 2011 APS Topical Conference on Shock ...

  19. Prasanna Balaprakash | Argonne Leadership Computing Facility

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    IL 60439 630-252-1109 pbalapra@mcs.anl.gov Specialities: Optimization under uncertainty; Artificial intelligence algorithms for large-scale optimization; Automated algorithm...

  20. Conferences and Workshops | Advanced Photon Source

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    Argonne National Laboratory, Argonne, IL October 15-19 7th International Conference on Mechanical Engineering Design of Synchrotron Radiation Equipment and Instrumentation...

  1. Providence Heights Wind Farm | Open Energy Information

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    Status In Service Owner Iberdrola Renewables Developer Midwest Wind Energy Location Bureau County IL Coordinates 41.264075, -89.580853 Show Map Loading map......

  2. Compositions and methods useful for ionic liquid treatment of biomass

    DOE Patents [OSTI]

    Dibble, Dean C.; Cheng, Aurelia; George, Anthe

    2014-07-29

    The present invention provides for novel compositions and methods for recycling or recovering ionic liquid used in IL pretreated cellulose and/or lignocellulosic biomass (LBM).

  3. March 2015 Most Viewed Documents for Chemistry | OSTI, US Dept...

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    ... Dept. of Nuclear Chemistry (1995) 40 Recycling galvanized steel: Operating experience and benefits Dudek, F.J.; Daniels, E.J. Argonne National Lab., IL (United States); Morgan, ...

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    for Plutonium, Amarillo, TX (United States) AmeriFlux Ames Laboratory (AMES), Ames, IA (United States) Argonne National Laboratory (ANL), Argonne, IL (United States) Argonne...

  5. BOA-2012-00185-CResponse

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    a written appeal to the Director, Office of Hearings and Appeals, at HG-1IL'Enfant Plaza Building, Department of Energy, 1000 Independence Avenue, SW, Washington, DC...

  6. ATLAS_Strategic_Plan_09_v5

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    IL November 2009 2 Introduction This strategic plan is developed jointly by the ATLAS user community and the Physics Division at Argonne National Laboratory. This plan is a...

  7. Atlas Material Testing Solutions | Open Energy Information

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    Atlas Material Testing Solutions Jump to: navigation, search Name: Atlas Material Testing Solutions Place: Chicago, IL Zip: 60613 Website: atlas-mts.com Coordinates: 41.9529209,...

  8. EV Everywhere Electric Drive Workshop: Preliminary Target-Setting...

    Broader source: Energy.gov (indexed) [DOE]

    Workshop: Preliminary Target-Setting Framework Jacob Ward, Vehicle Technologies Senior Analyst July 24, 2012 Doubletree-Rosemont, Chicago, IL For this Analysis, Three "EV "...

  9. Marquis Energy LLC | Open Energy Information

    Open Energy Info (EERE)

    Name: Marquis Energy LLC Place: Hennepin, Illinois Zip: 61327 Product: A Babcock & Brown company organized to build and operate a 100m gallon ethanol plant in Hennepin, IL....

  10. GSG Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    energy Facility Type Commercial Scale Wind Facility Status In Service Owner Babcock & Brown Developer FPC Services Location Lee and LaSalle Counties IL Coordinates 41.710895,...

  11. Randolph Eastern School Corporation | Open Energy Information

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    Sector Wind energy Facility Type Community Wind Facility Status In Service Owner Performance Services Energy Purchaser AEP - Indiana Michigan Power Location Union City IL...

  12. The City of Union City | Open Energy Information

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    Sector Wind energy Facility Type Community Wind Facility Status In Service Owner Performance Services Energy Purchaser AEP - Indiana Michigan Power Location Union City IL...

  13. A 5;#8242; cytosine binding pocket in Puf3p specifies regulation...

    Office of Scientific and Technical Information (OSTI)

    Argonne, IL (US) Sponsoring Org: NIH Country of Publication: United States Language: ENGLISH Word Cloud More Like This Full Text Journal Articles DOI: 10.1073pnas.0812079106...

  14. Graham Fletcher | Argonne Leadership Computing Facility

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    Graham Fletcher Principal Project Specialist in Computational Science Graham Fletcher Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 1123 Argonne, IL 60439 ...

  15. Francois Tessier | Argonne Leadership Computing Facility

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    Francois Tessier Postdoctoral Appointee Argonne National Laboratory 9700 S. Cass Avenue Bldg. 240 / Wkstn. 4E19 Argonne, IL 60439 630-252-5068 ftessier

  16. Gabe West | Argonne Leadership Computing Facility

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    Gabe West HPC Systems Administrator Specialist Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Rm. 1120 Argonne, IL 60439 630-252-1094 gwest

  17. George Rojas | Argonne Leadership Computing Facility

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    George Rojas Consultant/Software Engineer Argonne National Laboratory 9700 S. Cass Avenue Bldg. 240 - Rm. 3122 Argonne, IL 60439 630-252-5569 rojas

  18. DOE Zero Energy Ready Home Case Study: Weiss Building & Development LLC,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    System Home, River Forest, IL | Department of Energy LLC, System Home, River Forest, IL DOE Zero Energy Ready Home Case Study: Weiss Building & Development LLC, System Home, River Forest, IL Case study of a DOE Zero Energy Ready Home in River Forest, IL, that scored HERS 17 without PV. This 4,763-square-foot custom passive house has R-54 ICF walls, a vented attic with R-100 blown fiberglass, plus R-40 rigid EPS under the slab, triple-pane windows, two ductless mini-split heat pumps, and

  19. DOE Zero Energy Ready Home Case Study: Weiss Building & Development LLC.,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Custom Home, Downers Grove, IL | Department of Energy LLC., Custom Home, Downers Grove, IL DOE Zero Energy Ready Home Case Study: Weiss Building & Development LLC., Custom Home, Downers Grove, IL Case study of a DOE Zero Energy Ready Home in Downers Grove, IL, that scored HERS 35 without PV. This 3,600-square-foot custom home has advanced framed walls with R-23 dense-packed fiberglass plus R-13 rigid polyiso, a sealed attic with open-cell spray foam, a pier foundation, and 95% efficient

  20. DARK MATTER HALO PROFILES OF MASSIVE CLUSTERS: THEORY VERSUS...

    Office of Scientific and Technical Information (OSTI)

    Argonne, IL 60439 (United States) Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States) Harvard-Smithsonian Center for Astrophysics, ...

  1. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    International Laboratory of Materials Science and Nanotechnology" Name Name ORCID Search ... States) Argonne National Laboratory-Advanced Photon Source, Argonne, IL (United ...

  2. User:Hakan28 | Open Energy Information

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    illerden gelen insanlar ile birlikte Mudanya'nn nfusu ve geliimi artyor. Bursa inaat Bursa Marmara Blgesi'nin stanbul'dan sonraki en nemli il sralamasnda...

  3. The structural origin of the hard-sphere glass transition in...

    Office of Scientific and Technical Information (OSTI)

    Shanghai Jiao Tong Univ., Shanghai (China) Argonne National Lab. (ANL), Argonne, IL (United States) Chinese Academy of Sciences (CAS), Shanghai (China) Shanghai Jiao Tong Univ., ...

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    Office of Scientific and Technical Information (OSTI)

    Photon Source, Argonne, IL (United States) Atlanta Regional Office, Atlanta, GA (United States) Atmospheric System Research Bartlesville Project Office, OK (United...

  5. EV Everywhere Batteries Workshop- Beyond Lithium Ion Breakout Session Report

    Broader source: Energy.gov [DOE]

    Breakout session presentation for the EV Everywhere Grand Challenge: Battery Workshop on July 26, 2012 held at the Doubletree O'Hare, Chicago, IL.

  6. Extraction of solubles from plant biomass for use as microbial...

    Office of Scientific and Technical Information (OSTI)

    biomass with a cellulase enzyme-producing growth medium (such T. reesei) in the presence ... Research Org: Chicago Operations Office, Argonne, IL (United States) Sponsoring Org: USDOE ...

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    Office of Scientific and Technical Information (OSTI)

    States) Chicago Regional Office, Chicago, IL (United States) Clinch River Breeder Reactor Project, Oak Ridge, TN (United States) DOE HSS Office of Classification, Office of...

  8. Vestas USA | Open Energy Information

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    USA Jump to: navigation, search Name: Vestas USA Place: Rolling Meadows, Illinois Zip: IL 60008-4030 Sector: Wind energy Product: Vestas Wind Systems American arm. References:...

  9. Ben Allen | Argonne Leadership Computing Facility

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    Ben Allen HPC Systems Administration Specialist Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2128 Argonne, IL 60439 630-252-0554 allen

  10. Bill Allcock | Argonne Leadership Computing Facility

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    Bill Allcock Manager, Advanced Integration Group Bill Allcock Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 1123 Argonne, IL 60439 630-252-7573 allcock

  11. Brian Toonen | Argonne Leadership Computing Facility

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    Brian Toonen Consultant/Software Engineer Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3123 Argonne, IL 60439 630-252-6722 toonen

  12. Cheetah Goletz | Argonne Leadership Computing Facility

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    Cheetah Goletz HPC Systems Administration Specialist Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 2D21 Argonne, IL 60439 630-252-1853 cheetah

  13. Grand Ridge II Wind Farm | Open Energy Information

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    Owner Invenergy Developer Invenergy Energy Purchaser AEP-Appalachian Power Location La Salle County IL Coordinates 41.15496, -88.750234 Show Map Loading map......

  14. Grand Ridge III Wind Farm | Open Energy Information

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    Owner Invenergy Developer Invenergy Energy Purchaser AEP-Appalachian Power Location La Salle County IL Coordinates 41.15496, -88.750234 Show Map Loading map......

  15. Grand Ridge Wind Farm | Open Energy Information

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    Scale Wind Facility Status In Service Owner Invenergy Developer Invenergy Location La Salle County IL Coordinates 40.999966, -88.401693 Show Map Loading map......

  16. Defining the functional determinants for RNA surveillance by...

    Office of Scientific and Technical Information (OSTI)

    Defining the functional determinants for RNA surveillance by RIG-I Citation Details ... Research Org: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL ...

  17. State Farm Insurance | Open Energy Information

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    Farm Insurance Jump to: navigation, search Name: State Farm Insurance Place: Bloomington, IL Website: www.statefarminsurance.com References: State Farm Insurance1 Information...

  18. DOE Awards 265 Million Hours of Supercomputing Time to Advance...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... AZ; University of California campuses at Davis, Los Angeles, Riverside, San Diego and Santa Cruz, CA; University of Chicago in IL; University of Colorado in Boulder, CO; ...

  19. Union County, Illinois: Energy Resources | Open Energy Information

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    Pass, Illinois Anna, Illinois Cobden, Illinois Dongola, Illinois Jonesboro, Illinois Mill Creek, Illinois Retrieved from "http:en.openei.orgwindex.php?titleUnionCounty,Il...

  20. Microsoft PowerPoint - Kumar_2015_CNMSUserProjectHighlight_Nanoscale...

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    which can be significantly different from those observed in conventional polyelectrolytes. Strong electrostatic correlations in PolyILs tend to enhance the effects of...

  1. Brian K. Radak | Argonne Leadership Computing Facility

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    K. Radak Postdoctoral Appointee Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 1D16 Argonne, IL 60439 630-252-8643 bradak@anl...

  2. Jeffrey D. Emberson | Argonne Leadership Computing Facility

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    Jeffrey D. Emberson Postdoctoral Appointee Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 2C6 Argonne, IL 60439 630-252-5770 jemberson@anl

  3. Joan Stover | Argonne Leadership Computing Facility

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    Joan Stover Administrative Secretary Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 1D29 Argonne, IL 60439 630-252-0212 jstover

  4. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    Cass Avenue HEP Argonne IL United States E mail zachos anl gov CLASSICAL AND QUANTUM MECHANICS GENERAL PHYSICS COMPACTIFICATION DUALITY FERMIONS GAUGE INVARIANCE HOLOGRAPHY MANY...

  5. Christopher T. [Fermi National Accelerator Laboratory, P.O. Box...

    Office of Scientific and Technical Information (OSTI)

    IL 60439-4815 (United States), E-mail: zachos@anl.gov 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; COMPACTIFICATION; DUALITY; FERMIONS; GAUGE INVARIANCE; HOLOGRAPHY;...

  6. Archer Daniels Midland | Open Energy Information

    Open Energy Info (EERE)

    Daniels Midland Address: 4666 Faries Parkway Place: Decatur, IL Zip: 62526 Sector: Biofuels Product: turn crops into renewable products Phone Number: 800-637-5843 Website:...

  7. Adrian C. Pope | Argonne Leadership Computing Facility

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    Adrian C. Pope Assistant Computational Scientist Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Rm. 11213 Argonne, IL 60439 630-252-8745 apope

  8. Anouar Benali | Argonne Leadership Computing Facility

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    Anouar Benali Assistant Computational Scientist Anouar Benali Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2127 Argonne, IL 60439 630-252-0058 benali@anl

  9. Ashley Boyle | Argonne Leadership Computing Facility

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    Ashley Boyle Administrative Secretary Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 3D16 Argonne, IL 60439 630-252-1385 aboyle@anl

  10. Yasaman Ghadar | Argonne Leadership Computing Facility

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    Yasaman Ghadar Postdoctoral Appointee Argonne National Laboratory 9700 S. Cass Avenue Bldg. 240 - Wkstn. 1C7 Argonne, IL 60439 630-252-1398 ghadar

  11. Ye Luo | Argonne Leadership Computing Facility

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    Ye Luo Postdoctoral Appointee - HPC Ye Luo Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 1D22 Argonne, IL 60439 630-252-3183 yeluo

  12. Enrico Fermi Achieves First Self Sustain Nuclear Chain Reaction...

    National Nuclear Security Administration (NNSA)

    Self Sustain Nuclear Chain Reaction Chicago, IL Metallurgical Laboratory scientists led by Enrico Fermi achieve the first self-sustained nuclear chain reaction in pile...

  13. Ultrafast terahertz gating of the polarization and giant nonlinear...

    Office of Scientific and Technical Information (OSTI)

    Additional Journal Information: Journal Volume: 27; Journal Issue: 41; Journal ID: ISSN 0935-9648 Publisher: Wiley Research Org: Argonne National Lab. (ANL), Argonne, IL (United ...

  14. Magnetic properties of GdT2Zn20 (T = Fe, Co) investigated by...

    Office of Scientific and Technical Information (OSTI)

    Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany) Argonne National Lab. (ANL), Argonne, IL (United States) Univ. Federal do ABC (UFABC), Sao Paulo (Brazil) Univ. Estadual ...

  15. A striking effect of ionic-liquid anions in the extraction of Sr2+ and Cs+ by dicyclohexano-18-crown-6

    SciTech Connect (OSTI)

    Luo, Huimin; Dai, Sheng; Bonnesen, Peter V; Haverlock, Tamara; Moyer, Bruce A; Buchanan III, A C

    2006-01-01

    The nature of the ionic-liquid (IL) anion has been found to have a remarkable effect on the solvent extraction of Sr2+ and Cs+ by dicyclohexano-18-crown-6 dissolved in ionic liquids. In particular, the extraction efficiency increases with the hydrophobicity of the IL anion as reflected by the solubility in water of ILs having a common cation. Since a cation-exchange mechanism is operating in these systems, the influence of the IL anion is in large part attributable to an expected Le Chatelier effect in which a greater aqueous concentration of IL cation, obtained when using an IL anion of lower hydrophobicity, opposes cation exchange. This dependence is opposite to that found for IL cations, indicating a significant advantage of using ILs with hydrophobic anions for cation extraction. Furthermore, the extraction selectivity for Sr2+ over Na+, K+, and Cs+ can be significantly improved through the use of hydrophobic anions for the ILs containing 1-ethyl-3-methylimidazolium or 1-butyl-3-methylimidazolium cations.

  16. Designing defect spins for wafer-scale quantum technologies ...

    Office of Scientific and Technical Information (OSTI)

    Authors: Koehl, William F. 1 ; Seo, Hosung 2 ; Galli, Giulia 1 ; Awschalom, David D. 1 + Show Author Affiliations Argonne National Lab. (ANL), Argonne, IL (United States); ...

  17. Other Participants 1992 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    NM Shoreham-Wading River High School , Shoreham , NY Thomas Jefferson High School , Alexandria , VA Wheaton North High School , Wheaton , IL Window Rock High School , Fort Defiance

  18. Manufacturing Demonstration Facilities Workshop Agenda, March...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Manufacturing Demonstration Facilities Workshop Marriott Springhill Suites O'Hare - Chicago, IL March 12, 2012 Objectives Introduce the manufacturing community to the U.S. DOE ...

  19. Future Energy Enterprises | Open Energy Information

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    Enterprises Jump to: navigation, search Name: Future Energy Enterprises Place: Wilmette, IL Website: futureenergyenterprises.biz References: Partnership for Advanced Residential...

  20. Blending municipal solid waste with corn stover for sugar production...

    Office of Scientific and Technical Information (OSTI)

    applied an enzyme free process by adding mineral acid and water directly into the ILbiomass slurry to induce hydrolysis. With the acidolysis process in the IL...

  1. Project Profile: Thermally-Stable Ionic Liquid Carriers forNanopartic...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    From the initial screening of IL thermal stabilities, the best candidates are being further investigated with the addition of nanoparticles. Innovation During the last two decades, ...

  2. Non-aqueous electrolyte for lithium-ion battery (Patent) | DOEPatents

    Office of Scientific and Technical Information (OSTI)

    Inventors: Zhang, Lu ; Zhang, Zhengcheng ; Amine, Khalil Issue Date: 2014-04-15 OSTI Identifier: 1129197 Assignee: UChicago Argonne, LLC (Chicago, IL) ANL Patent Number(s): ...

  3. Electroactive materials for rechargeable batteries (Patent) ...

    Office of Scientific and Technical Information (OSTI)

    Inventors: Wu, Huiming ; Amine, Khalil ; Abouimrane, Ali Issue Date: 2015-04-21 OSTI Identifier: 1178258 Assignee: UChicago Argonne, LLC (Chicago, IL) CHO Patent Number(s): ...

  4. Redox shuttles for lithium ion batteries (Patent) | DOEPatents

    Office of Scientific and Technical Information (OSTI)

    Inventors: Weng, Wei ; Zhang, Zhengcheng ; Amine, Khalil Issue Date: 2016-03-22 OSTI Identifier: 1243310 Assignee: UCHICAGO ARGONNE, LLC (Chicago, IL) CHO Patent Number(s): ...

  5. Local Hotels | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Local Hotels Argonne Guest House Argonne National Laboratory 9700 South Cass Avenue, Building 460 Argonne, IL 60439 Reservations: 800/632-8990 or 630/739-6000 Fax: 630/739-1000 E-mail: argonne-guest-house@anl.gov Online reservations Additional Hotels AmeriSuites Burr Ridge 15 W. 90 N. Frontage Road Burr Ridge, IL 60521 Reservations: 630/323-7530 La Quinta 225 W. South Frontage Road Bolingbrook, IL 60440 Reservations: 630/226-0000 La Quinta 855 79th Street Willowbrook, IL 60527 Reservations:

  6. EV Everywhere Grand Challenge - Battery Workshop Agenda

    Broader source: Energy.gov (indexed) [DOE]

    7252012 EV Everywhere Grand Challenge -- Battery Workshop Thursday, July 26, 2012 - Doubletree O'Hare, Chicago, IL Event Objective: DOE aims to obtain stakeholder input on the...

  7. EV Everywhere Battery Workshop: Preliminary Target-Setting Framework

    Broader source: Energy.gov (indexed) [DOE]

    Chicago, IL For this Analysis, Three "EV " Scenarios 1. PHEV40 - reduces battery size while removing range issues, but involves the higher cost of two powertrains 2....

  8. DOE - Office of Legacy Management -- GSA 39th Street Warehouse...

    Office of Legacy Management (LM)

    IL.02-2 - DOE Report; FUSRAP Elimination Report for the Former General Services Administration 39th Street Warehouse 1716 Pershing Road Chicago, Illinois; September 30, 1985...

  9. The Building Research Council at the University of Illinois ...

    Open Energy Info (EERE)

    Research Council at the University of Illinois Jump to: navigation, search Name: The Building Research Council at the University of Illinois Place: Champaign, IL Information About...

  10. Fermilab Today

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL Violinist Paolo Castellani and guitarist Francesco Di Giandomenico play the colorful music from Argentina, Spain and Puerto Rico. They will present their latest album,...

  11. Bishop Hill II | Open Energy Information

    Open Energy Info (EERE)

    Owner MidAmerican Energy Developer Ivenergy Energy Purchaser Ameren Illinois Location Cambridge IL Coordinates 41.24438513, -90.09338379 Show Map Loading map......

  12. Community and Economic Development Association of Cook County...

    Open Energy Info (EERE)

    and Economic Development Association of Cook County (CEDA) Jump to: navigation, search Name: Community and Economic Development Association of Cook County (CEDA) Place: Chicago, IL...

  13. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    States) Chicago Operations Office, Argonne, IL ... Idaho National Engineering and Environmental Laboratory, Idaho ... and volume of the unit cell for orthorhombic ...

  14. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    IL (United States) Fernald Area Office (United States) Fernald Environmental Management Project, OH (United States) FluxNet General Atomics Site, San Diego, CA (United...

  15. The Secretary of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MEMORANDUM FOR HEADS OF DEPARTMENTAL ELEMENTS FROM: STEVEN CHU Il Subject: Enterprise Risk Management (ERM) Framework for Directives Thi s memorandum explains a new...

  16. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    IL (United States) Fernald Area Office (United States) Fernald Environmental Management Project, OH (United States) General Atomics Site, San Diego, CA (United States)...

  17. Equation of state and high-pressure/high-temperature phase diagram...

    Office of Scientific and Technical Information (OSTI)

    Argonne, IL (US) Sponsoring Org: FOREIGNDOE - BASIC ENERGY SCIENCES Country of Publication: United States Language: ENGLISH Word Cloud More Like This Full Text Journal Articles ...

  18. Transcendental Meditation

    ScienceCinema (OSTI)

    None

    2011-04-25

    K.Wallace, qui vient des Etats Unis, parle des effects physiologiques de la méditation transcendantale. Il a fait son bachelor en physique à l'Université de Los Angeles et son doctorat en physiologie aussi à Los Angeles, mais à l'Institut de Recherche sur le cerveau. Il travaille maintenat à Harvard Medical School ou il continue des recherches biochimiques et physiologiques sur l'application médicale de la méditation transcendantale. Il s'occupe principalement des maladies cardiaques et de hypertension artérielle.

  19. The Midwest Energy Efficiency Alliance | Open Energy Information

    Open Energy Info (EERE)

    Midwest Energy Efficiency Alliance Jump to: navigation, search Name: The Midwest Energy Efficiency Alliance Place: Chicago, IL Information About Partnership with NREL Partnership...

  20. Structure and mechanism of activity-based inhibition of the EGF...

    Office of Scientific and Technical Information (OSTI)

    Authors: Park, Eunyoung ; Kim, Nayoung ; Ficarro, Scott B. ; Zhang, Yi ; Lee, Byung Il ; Cho, Ahye ; Kim, Kihong ; Park, Angela K.J. ; Park, Woong-Yang ; Murray, Bradley ; ...

  1. Introduction to computed microtomography and applications in...

    Office of Scientific and Technical Information (OSTI)

    Resource Relation: Related Information: CMS Workshop Lectures, Advanced Applications of Synchrotron Radiation in Clay Science Publisher: 2014; Tha Clay Minerals Society ;Urbana, IL ...

  2. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    From Quanta to the Continuum Opportunities for Mesoscale Science Crabtree George Argonne National Lab ANL Argonne IL United States Sarrao John Los Alamos National Lab LANL Los...

  3. From Quanta to the Continuum: Opportunities for Mesoscale Science...

    Office of Scientific and Technical Information (OSTI)

    Quanta to the Continuum: Opportunities for Mesoscale Science Crabtree, George Argonne National Lab. (ANL), Argonne, IL (United States); Sarrao, John Los Alamos National Lab....

  4. "Title","Creator/Author","Publication Date","OSTI Identifier...

    Office of Scientific and Technical Information (OSTI)

    From Quanta to the Continuum: Opportunities for Mesoscale Science","Crabtree, George Argonne National Lab. (ANL), Argonne, IL (United States); Sarrao, John Los Alamos National...

  5. NETL F 451.1/1-1, Categorical Exclusion Designation Form

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TX; Trimeric Corporation: Champaign, IL and Buda, TX. FESCCStorage Division Bruce Brown Brine Extraction and Treatment Strategies to Enhance Pressure Management... Project...

  6. Xiao Wang | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Xiao Wang Web Developer Associate Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Wkstn. 2D26 Argonne, IL 60439 630-252-1145 xiaowang...

  7. EV Everywhere Challenge Battery Workshop

    Broader source: Energy.gov [DOE]

    Backsplash for the EV Everywhere Grand Challenge: Battery Workshop on July 26, 2012 held at the Doubletree O'Hare, Chicago, IL.

  8. Slide 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in 2006 * Passive microwave remote sensing * Long experience with airborne, ship-borne, ground based microwave radiometers University of Illinois, Champaign, IL October 14-16,...

  9. Caterpillar | Open Energy Information

    Open Energy Info (EERE)

    Caterpillar Jump to: navigation, search Name: Caterpillar Place: Peoria, IL Website: www.cat.com References: NREL News Release: Reduce Truck Idling1 Information About Partnership...

  10. Sandia Energy - EC Publications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in the Energy Sector (76) Achieving Higher Energy Density in Flow Batteries at Lower Cost with MetILs (481) Advanced Energy Industries, Inc. SEGIS Developments (1772)...

  11. Richland Community College | Open Energy Information

    Open Energy Info (EERE)

    Community College Sector Wind energy Facility Type Small Scale Wind Facility Status In Service Location Decatur IL Coordinates 39.88666061, -88.89538586 Show Map Loading...

  12. MUTI | Open Energy Information

    Open Energy Info (EERE)

    MUTI Facility MUTI Sector Wind energy Facility Type Small Scale Wind Facility Status In Service Owner MUTI Energy Purchaser MUTI Location Champaign IL Coordinates 40.15017707,...

  13. Michael Papka | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Papka Division Director Michael Papka Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 4134 Argonne, IL 60439 630-252-1556 papka@anl.gov http:...

  14. Settler's Trail | Open Energy Information

    Open Energy Info (EERE)

    Developer E.ON Climate & Renewables North America Energy Purchaser Merchant Location Sheldon IL Coordinates 40.7626336, -87.54498482 Show Map Loading map......

  15. Comparative repository performance of plutonium forms - initial...

    Office of Scientific and Technical Information (OSTI)

    Publisher: American Nuclear Society, Inc.; American Society of Civil Engineers, La Grange Park, IL (United States) Country of Publication: United States Language: English Subject: ...

  16. Latest Documents and Notices | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hawaii Clean Energy Programmatic Environmental Impact Statement September 15, 2015 EA-1975: Supplement Analysis LINAC Coherent Light Source-Il, SLAC National Accelerator...

  17. Illinois Wind Energy | Open Energy Information

    Open Energy Info (EERE)

    Wind Energy Jump to: navigation, search Name: Illinois Wind Energy Place: Chicago, Illinois Zip: IL 60606 Sector: Wind energy Product: Developer of wind power generating facilities...

  18. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Nevada Test SiteNavarro-Intera, LLC New Brunswick Laboratory (NBL), Argonne, IL (United States) New York Support Office, New York, NY (United States) North American Aviation, Inc. ...

  19. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... LLC New Brunswick Laboratory (NBL), Argonne, IL (United States) New York ... The investigations were based on system modeling and laboratory evaluation. Both designs ...

  20. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... LLC New Brunswick Laboratory (NBL), Argonne, IL (United States) New York ... (1) corrosion (1) decomposition (1) evaluation (1) flowsheets (1) forecasting (1) ...

  1. Gob Nob | Open Energy Information

    Open Energy Info (EERE)

    Project Developer Rural Electric Convenience Cooperative Project Location Montgomery County IL Coordinates 39.4384551, -89.62847114 Show Map Loading map......

  2. US ITER Moving Forward Video

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL Site Consumption million Btu $0 $500 $1,000 $1,500 $2,000 $2,500 US ENC IL Expenditures dollars ALL ENERGY average per household (excl. transportation) 0 2,000 4,000 6,000 8,000 10,000 12,000 US ENC IL Site Consumption kilowatthours $0 $250 $500 $750 $1,000 $1,250 $1,500 US ENC IL Expenditures dollars ELECTRICITY ONLY average per household * Illinois households use 129 million Btu of energy per home, 44% more than the U.S. average. * High consumption, combined with low costs for heating fuels

  3. Susan Gregurich | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Gregurich Administrative Secretary Susan Gregurich Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 2D24 Argonne IL, 60439 630-252-7120 gregurich@anl

  4. Chel Lancaster | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Chel Lancaster Outreach Chel Heinzel Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 2D22 Argonne, IL 60439 630-252-6138 chel

  5. Darin Wills | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Darin Wills Assistant Division Director Darin Wills Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3127 Argonne, IL 60439 630-252-0355 dwills

  6. David Martin | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David Martin Industrial Outreach Lead David Martin Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 3126 Argonne, IL 60439 630-252-0929 dem

  7. Panther Creek | Open Energy Information

    Open Energy Info (EERE)

    Construction Owner Affinity WindSuzlon Energy Limited Developer Surity Wind Location Pike County IL Coordinates 39.607275, -90.85556 Show Map Loading map......

  8. Illinois Rural Electric Cooperative Wind Farm | Open Energy Informatio...

    Open Energy Info (EERE)

    Electric Cooperative Energy Purchaser Illinois Rural Electric Cooperative Location Pike County IL Coordinates 39.6189, -90.9627 Show Map Loading map......

  9. John K. Holton | Open Energy Information

    Open Energy Info (EERE)

    IL Information About Partnership with NREL Partnership with NREL Yes Partnership Type Test & Evaluation Partner Partnering Center within NREL Electricity Resources & Building...

  10. Eric A. Ross | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A. Ross HPC Systems Administration Specialist Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 2123 Argonne, IL 60439 630-252-6175 eross...

  11. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    IL (United States) Atlanta Regional Office, Atlanta, GA (United States) Atmospheric System Research Bartlesville Project Office, OK (United States) Battelle Memorial...

  12. TiO2 nanotube arrays grown in ionic liquids: high-efficiency in photocatalysis and pore-widening

    SciTech Connect (OSTI)

    Li, Huaqing; Qu, Jun; Cui, Qingzhou; Xu, Hanbing; Luo, Huimin; Chi, Miaofang; Meisner, Roberta Ann; Wang, Wei; Dai, Sheng

    2011-01-01

    Debris-free, long, well-separated TiO2 nanotube arrays were obtained using an ionic liquid (IL) as electrolyte. The high conductivity of IL resulted in fast pore widening and few contaminants from electrolyte decomposition leading to high photocatalytic efficiency in water splitting.

  13. Workplace Charging Challenge Partner: Argonne National Laboratory |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Argonne National Laboratory Workplace Charging Challenge Partner: Argonne National Laboratory Workplace Charging Challenge Partner: Argonne National Laboratory Joined the Challenge: June 2014 Headquarters: Argonne, IL Charging Location: Argonne, IL Domestic Employees: 3,400 Argonne National Laboratory is a multidisciplinary science and engineering research center where researchers work to address vital national challenges in clean energy, environment, technology and

  14. EFFECTS OF GAMMA RADIATION ON ELECTROCHEMICAL PROPERTIES OF IONIC LIQUIDS

    SciTech Connect (OSTI)

    Visser, A; Nicholas Bridges, N; Thad Adams, T; John Mickalonis, J; Mark02 Williamson, M

    2009-04-21

    The electrochemical properties of ionic liquids (ILs) make them attractive for possible replacement of inorganic salts in high temperature molten salt electrochemical processing of nuclear fuel. To be a feasible replacement solvent, ILs need to be stable in moderate and high doses of radiation without adverse chemical and physical effects. Here, we exposed seven different ILs to a 1.2 MGy dose of gamma radiation to investigate their physical and chemical properties as they related to radiological stability. The azolium-based ILs experienced the greatest change in appearance, but these ILs were chemically more stable to gamma radiation than some of the other classes of ILs tested, due to the presence of aromatic electrons in the azolium ring. All the ILs exhibited a decrease in their conductivity and electrochemical window (at least 1.1 V), both of which could affect the utility of ILs in electrochemical processing. The concentration of the irradiation decomposition products was less than 3 mole %, with no impurities detectable using NMR techniques.

  15. Impressions on Chinas Popular Republic

    ScienceCinema (OSTI)

    None

    2011-04-25

    Le D.G. Jentschke présente le Prof.Yang, née en 1922 en Chine où il a aussi fait ses études; il parle de ses impressions en Chine (p.e. mariage etc....) avec présentation des dias

  16. 2014 Retail Power Marketers Sales- Residential

    U.S. Energy Information Administration (EIA) Indexed Site

    ... 227,638.8 5.07 Green Mountain Energy Company IL Power Marketer 24,959 190,336 16,176.4 8.50 Homefield Energy IL Power Marketer 677,675 5,726,072 347,820.0 6.07 IDT Energy, Inc. ...

  17. Solar Power

    ScienceCinema (OSTI)

    None

    2011-04-25

    Le Prof. Broda, Prof. de Biochimie, Physique et Radiochimie à l'Université de Vienne, ville où il est né et où il a étudié, fait une brillante carrière accadémique et nous parle de l'énergie solaire.

  18. Club of Rome

    ScienceCinema (OSTI)

    None

    2011-04-25

    Le Club de Rome s'est fait connaître du grand public par la publication du premier ouvrage "Halte à la croissance" qui a fait l'object d'un débat, il y a 2 ans. Le Prof. Tinbergen a commencé par s'adonner à la physique, il est docteur en physique et très tôt il s'est tourné vers les problèmes sociaux économiques. Il est expert auprès des nombreux gouvernements et organisations internationales et il a vu ses travaux couronnés par le prix Nobel en 1969.

  19. Phase-Changing Ionic Liquids: CO2 Capture with Ionic Liquids Involving Phase Change

    SciTech Connect (OSTI)

    2010-07-01

    IMPACCT Project: Notre Dame is developing a new CO2 capture process that uses special ionic liquids (ILs) to remove CO2 from the gas exhaust of coal-fired power plants. ILs are salts that are normally liquid at room temperature, but Notre Dame has discovered a new class of ILs that are solid at room temperature and change to liquid when they bind to CO2. Upon heating, the CO2 is released for storage, and the ILs re-solidify and donate some of the heat generated in the process to facilitate further CO2 release. These new ILs can reduce the energy required to capture CO2 from the exhaust stream of a coal-fired power plant when compared to state-ofthe- art technology.

  20. Hydrogen-bonding interactions and protic equilibria in room-temperature ionic liquids containing crown ethers.

    SciTech Connect (OSTI)

    Marin, T.; Shkrob, I.; Dietz, M.

    2011-04-14

    Nuclear magnetic resonance (NMR) spectroscopy has been used to study hydrogen-bonding interactions between water, associated and dissociated acids (i.e., nitric and methanesulfonic acids), and the constituent ions of several water-immiscible room-temperature ionic liquids (ILs). In chloroform solutions also containing a crown ether (CE), water molecules strongly associate with the IL ions, and there is rapid proton exchange between these bound water molecules and hydronium associated with the CE. In neat ILs, the acids form clusters differing in their degree of association and ionization, and their interactions with the CEs are weak. The CE can either promote proton exchange between different clusters in IL solution when their association is weak or inhibit such exchange when the association is strong. Even strongly hydrophobic ILs are shown to readily extract nitric acid from aqueous solution, typically via the formation of a 1:1:1 {l_brace}H{sub 3}O{sup +} {center_dot} CE{r_brace}NO{sub 3}{sup -} complex. In contrast, the extraction of methanesulfonic acid is less extensive and proceeds mainly by IL cation-hydronium ion exchange. The relationship of these protic equilibria to the practical application of hydrophobic ILs (e.g., in spent nuclear fuel reprocessing) is discussed.

  1. Oil-Miscible and Non-Corrosive Phosphonium Ionic Liquids as Candidate Lubricant Additives

    SciTech Connect (OSTI)

    Yu, Bo; Bansal, Dinesh G; Qu, Jun; Sun, Xiaoqi; Luo, Huimin; Dai, Sheng; Blau, Peter Julian; Bunting, Bruce G; Mordukhovich, Gregory; Smolenski, Donald

    2012-01-01

    Ionic liquids (ILs) have been receiving considerable attention from the lubricants industry as potential friction and wear-reducing additives, but their solubility in oils is an issue. Unlike most ionic liquids that are insoluble in non-polar hydrocarbon oils, this study reports phosphonium-based ILs (PP-ILs) that are fully miscible with both mineral oil-based and synthetic lubricants. Both the cation and anion in quaternary structures, long alkyl chains, and capability of pairing the cation and the anion via a H-O bond are hypothesized to improve the compatibility between ions and neutral oil molecules. The measured viscosities of the oil-IL blends agree well with the Refutas equation that is for solutions containing multiple components. High thermal stability and non-corrosiveness were observed for the PP-ILs. Effective friction reduction and anti-wear functionality have been demonstrated in tribological tests when adding 5 wt% of a PP-IL into a base oil, suggesting potential applications for using the oil-miscible PP-ILs as lubricant additives.

  2. Deprotonation and oligomerization in photo-, radiolytically and electrochemically induced redox reactions in hydrophobic alkylalkylimidazolium ionic liquids.

    SciTech Connect (OSTI)

    Shkrob, I . A.; Chemical Sciences and Engineering Division

    2010-01-14

    Radical chemistry initiated by one-electron reduction of 1-methyl-3-alkylimidazolium cations in the corresponding ionic liquids (ILs) is examined. The reaction scheme is examined in light of the recent experimental data on photo-, radiation-, and electrochemically induced degradation of the practically important hydrophobic alkylimidazolium ILs. It is suggested that the primary species leading to the formation of the oligomers and acidification of the IL is a {sigma}{sigma}* dimer radical cation that loses a proton, yielding a neutral radical whose subsequent reactions produce C(2)-C(2) linked oligomers, both neutral and charged. The neutral oligomers (up to the tetramer) account for the features observed in the NMR spectra of cathodic liquid generated in electrolytic breakdown of the IL solvent. In photolysis and radiolysis, these neutral species and/or their radical precursors are oxidized by radical (ions) derived from the counteranions, and only charged dimers are observed. The dication dimers account for the features observed in the mass spectra of irradiated ILs. The products of these ion radical and radical reactions closely resemble those generated via carbene chemistry, without the formation of the carbene via the deprotonation of the parent cation. As the loss of 2-protons increases the proticity of the irradiated IL, it interferes with the extraction of metal ions by ionophore solutes, while the formation of the oligomers modifies solvent properties. Thus, the peculiarities of radical chemistry in the alkylimidazolium ILs have significant import for their practical applications.

  3. Receptor expression is essential for proliferation induced by dimerized Jak kinases

    SciTech Connect (OSTI)

    Fujii, Hodaka

    2008-06-13

    Two members of Jak kinases, Jak1 and Jak3, are associated with the cytoplasmic domains of the interleukin-2 (IL-2) receptor (IL-2R) {beta} chain (IL-2R{beta}) and the common cytokine receptor {gamma} chain ({gamma}c), respectively, and accumulating evidence indicates their functional importance in IL-2 signaling. Here, I showed that coumermycin-induced chemical heterodimerization of Jak1 and Jak3 but not homodimerization of Jak1 or Jak3 induces cell proliferation of an IL-2R-reconstituted cell line. In this regard, expression of IL-2R{beta} was essential for cell proliferation by chemical heterodimerization of Jak1 and Jak3, indicating that dimerized Jak1 and Jak3 induce heterodimerization of IL-2R{beta} and {gamma}c, which may activate receptor-bound signaling molecules. Previous reports using chemical dimerization suggest that dimerization of Jak kinases is sufficient to induce cell proliferation. The present study indicates that re-evaluation of this conclusion is necessary and that interpretation of functional analysis of signaling molecules using chemical dimerizers needs more careful assessment.

  4. Detection of three nonsense mutations and one missense mutation in the interleukin-2 receptor [gamma] chain gene in SCIDX1 that differently affect the mRNA processing

    SciTech Connect (OSTI)

    Markiewicz, S.; Fischer, A.; Saint Basile, G. de ); Subtil, A.; Dautry-Varsat, A. )

    1994-05-01

    The interleukin-2 receptor [gamma] (IL-2R[gamma]) chain gene encodes a 64-kDa protein that not only composes the high-affinity form of the IL-2 binding receptor in association with the 2R [alpha] and [beta] chains, but also participates in at least the IL-4 and IL-7 receptor complexes. Mutations in this gene have recently been shown to cause X-linked severe combined immunodeficiency (SCIDX1). This disease of the immune system results from an early block of T lymphocyte and natural killer (NK) cell differentiation, which leads to a severe cellular and humoral immune defect that is lethal unless treated by bone marrow transplantation. Analysis of the IL-2R[gamma] gene in SCIDX1 patients has revealed the presence of heterogeneous mutations principally located in the extracellular domain of the molecule. We report here three intraexonic mutations and one deletion in the IL-2R[gamma] gene in four SCIDX1 patients. These mutations appear to differentially affect RNA processing, either by decreasing IL-2R[gamma] mRNA level or by the skipping of a constitutive exon. 16 refs., 1 fig.

  5. Kinetics of expression of interleukin 2 receptors on class I and class II restricted murine T cell clones

    SciTech Connect (OSTI)

    Churilla, A.; Braciale, V.; Braciale, T.

    1986-03-05

    The kinetics of interleukin 2 receptor (IL-2R) expression has been examined on various class I and class II restricted, influenza specific murine T cell clones. Expression and relative levels of IL-2R were examined by Fluorescence Activated Cell Sorter analysis utilizing 3 anti-murine IL-2R monoclonal antibodies. Receptor expression was analyzed by scatchard analysis using radiolabeled recombinant human interleukin 2 to access the number of high and low affinity IL-2R per cell as well as the affinity of binding. The clones tested bound all 3 monoclonal antibodies and were inhibited in an IL-2 dependent proliferation assay by the addition of the antibodies to the culture. There was, however, differing degrees of inhibition ranging up to 99%, depending on the clone and the antibody used. IL-2R expression was detectable as early as 4-6 hours after antigenic stimulation of quiescent cells. After maximal levels of receptors were expressed, which was about 24 hours after stimulation, expression of IL-2R decreased with time on all clones examined (both class I and class II restricted). Differing rates of receptor loss is seen however, with some class II restricted clones retaining relatively high levels of receptors.

  6. Identification of a haloalkaliphilic and thermostable cellulase with improved ionic liquid tolerance

    SciTech Connect (OSTI)

    Zhang, Tao; Datta, Supratim; Eichler, Jerry; Ivanova, Natalia; Axen, Seth D.; Kerfeld, Cheryl A.; Chen, Feng; Kyrpides, Nikos; Hugenholtz, Philip; Cheng, Jan-Fang; Sale, Kenneth L.; Simmons, Blake; Rubin, Eddy

    2011-02-17

    Some ionic liquids (ILs) have been shown to be very effective solvents for biomass pretreatment. It is known that some ILs can have a strong inhibitory effect on fungal cellulases, making the digestion of cellulose inefficient in the presence of ILs. The identification of IL-tolerant enzymes that could be produced as a cellulase cocktail would reduce the costs and water use requirements of the IL pretreatment process. Due to their adaptation to high salinity environments, halophilic enzymes are hypothesized to be good candidates for screening and identifying IL-resistant cellulases. Using a genome-based approach, we have identified and characterized a halophilic cellulase (Hu-CBH1) from the halophilic archaeon, Halorhabdus utahensis. Hu-CBH1 is present in a gene cluster containing multiple putative cellulolytic enzymes. Sequence and theoretical structure analysis indicate that Hu-CBH1 is highly enriched with negatively charged acidic amino acids on the surface, which may form a solvation shell that may stabilize the enzyme, through interaction with salt ions and/or water molecules. Hu-CBH1 is a heat tolerant haloalkaliphilic cellulase and is active in salt concentrations up to 5 M NaCl. In high salt buffer, Hu-CBH1 can tolerate alkali (pH 11.5) conditions and, more importantly, is tolerant to high levels (20percent w/w) of ILs, including 1-allyl-3-methylimidazolium chloride ([Amim]Cl). Interestingly, the tolerances to heat, alkali and ILs are found to be salt-dependent, suggesting that the enzyme is stabilized by the presence of salt. Our results indicate that halophilic enzymes are good candidates for the screening of IL-tolerant cellulolytic enzymes.

  7. Ionic Liquids as Novel Lubricants and /or Lubricant Additives

    SciTech Connect (OSTI)

    Qu, J.; Viola, M. B.

    2013-10-31

    This ORNL-GM CRADA developed ionic liquids (ILs) as novel lubricants or oil additives for engine lubrication. A new group of oil-miscible ILs have been designed and synthesized with high thermal stability, non-corrosiveness, excellent wettability, and most importantly effective anti-scuffing/anti-wear and friction reduction characteristics. Mechanistic analysis attributes the superior lubricating performance of IL additives to their physical and chemical interactions with metallic surfaces. Working with a leading lubricant formulation company, the team has successfully developed a prototype low-viscosity engine oil using a phosphonium-phosphate IL as an anti-wear additive. Tribological bench tests of the IL-additized formulated oil showed 20-33% lower friction in mixed and elastohydrodynamic lubrication and 38-92% lower wear in boundary lubrication when compared with commercial Mobil 1 and Mobil Clean 5W-30 engine oils. High-temperature, high load (HTHL) full-size engine tests confirmed the excellent anti-wear performance for the IL-additized engine oil. Sequence VID engine dynamometer tests demonstrated an improved fuel economy by >2% for this IL-additized engine oil benchmarked against the Mobil 1 5W-30 oil. In addition, accelerated catalyst aging tests suggest that the IL additive may potentially have less adverse impact on three-way catalysts compared to the conventional ZDDP. Follow-on research is needed for further development and optimization of IL chemistry and oil formulation to fully meet ILSAC GF-5 specifications and further enhance the automotive engine efficiency and durability.

  8. Southern Great Plains

    Energy Savers [EERE]

    Southern Great Plains Climate C hange a nd t he U .S. E nergy S ector: Regional v ulnerabilities a nd r esilience s olutions Summary i n B rief The S outhern G reat P lains r egion, c omprising K ansas, O klahoma, and T exas, c ontains o il a nd g as i nfrastructure c ritical t o t he nation's e nergy s upply, i ncluding n umerous o ffshore p latforms, onshore o il a nd g as w ells, o il r efineries, n atural g as p rocessing plants, p ipelines, a nd s hipping t erminals. M any o f t hese a

  9. computational-structural-mechanics-training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Table of Contents Date Location Training Course: HyperMesh and HyperView April 12-14, 2011 Argonne TRACC Argonne, IL Introductory Course: Developing Compute-efficient, Quality Models with LS-PrePost® 3 on the TRACC Cluster October 21-22, 2010 Argonne TRACC West Chicago, IL Modeling and Simulation with LS-DYNA®: Insights into Modeling with a Goal of Providing Credible Predictive Simulations February 11-12, 2010 Argonne TRACC West Chicago, IL Introductory Course: Using LS-OPT® on the TRACC

  10. Flow cytometric analysis of expression of interleukin-2 receptor beta chain (p70-75) on various leukemic cells

    SciTech Connect (OSTI)

    Hoshino, S.; Oshimi, K.; Tsudo, M.; Miyasaka, M.; Teramura, M.; Masuda, M.; Motoji, T.; Mizoguchi, H. )

    1990-08-15

    We analyzed the expression of the interleukin-2 receptor (IL-2R) beta chain (p70-75) on various leukemic cells from 44 patients by flow cytometric analysis using the IL-2R beta chain-specific monoclonal antibody, designated Mik-beta 1. Flow cytometric analysis demonstrated the expression of the IL-2R beta chain on granular lymphocytes (GLs) from all eight patients with granular lymphocyte proliferative disorders (GLPDs), on adult T-cell leukemia (ATL) cells from all three patients with ATL, and on T-cell acute lymphoblastic leukemia (T-ALL) cells from one of three patients with T-ALL. Although GLs from all the GLPD patients expressed the IL-2R beta chain alone and not the IL-2R alpha chain (Tac-antigen: p55), ATL and T-ALL cells expressing the beta chain coexpressed the alpha chain. In two of seven patients with common ALL (cALL) and in both patients with B-cell chronic lymphocytic leukemia, the leukemic cells expressed the alpha chain alone. Neither the alpha chain nor the beta chain was expressed on leukemic cells from the remaining 28 patients, including all 18 patients with acute nonlymphocytic leukemia, five of seven patients with cALL, all three patients with multiple myeloma, and two of three patients with T-ALL. These results indicate that three different forms of IL-2R chain expression exist on leukemic cells: the alpha chain alone; the beta chain alone; and both the alpha and beta chains. To examine whether the results obtained by flow cytometric analysis actually reflect functional aspects of the expressed IL-2Rs, we studied the specific binding of 125I-labeled IL-2 (125I-IL-2) to leukemic cells in 18 of the 44 patients. In addition, we performed 125I-IL-2 crosslinking studies in seven patients. The results of IL-2R expression of both 125I-IL-2 binding assay and crosslinking studies were in agreement with those obtained by flow cytometric analysis.

  11. 2009 National Electric Transmission Congestion Study Workshops...

    Office of Environmental Management (EM)

    June 11, 2008 San Francisco, CA June 18, 2008 Oklahoma City, OK July 9, 2008 Hartford, CT July 29, 2008 Atlanta, GA August 6, 2008 Las Vegas, NV September 17, 2008 Chicago, IL DOE ...

  12. OAK RIDGE : I NATIONAL LABORATORY

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    ... commercial metal fabricators engaged by DuPont, a MED prime contractor, to fabricate a ... IL?, included machining and finishing slugs from uranium metal rod supplied by DuPont. ...

  13. Nathan V. Roberts | Argonne Leadership Computing Facility

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    Nathan V. Roberts Postdoctoral Appointee Nathan V. Roberts Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 1D18 Argonne, IL 60439 630-252-0036 nvroberts@alcf.anl

  14. Membrane Technology Workshop

    Broader source: Energy.gov [DOE]

    At the Membrane Technology Workshop (held July 24, 2012, in Rosemont, IL), stakeholders from industry and academia explored the status of membrane research and development (R&D). Participants ...

  15. Class 1 Permit Modification Notification

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    Waste Bureau New Mexico Environment Department 2905 Rodeo Park Drive East, Bu il ding 1 Santa Fe, New Mexico 87505-6303 JUL 0 5 2011 Subject: Notification of a Class 1 Permit...

  16. Ti Leggett | Argonne Leadership Computing Facility

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    Ti Leggett Deputy Project Directcor & Deputy Director of Operations Argonne National Laboratory 9700 S. Cass Avenue Building 240 - Room 3132 Argonne, IL 60439 630-252-1937 tleggett

  17. Tommie L. Jackson | Argonne Leadership Computing Facility

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    Tommie L. Jackson HPC Systems Administration Specialist Argonne National Laboratory 9700 South Cass Avenue Building 240, Room 2123 Argonne, IL 60439 630-252-2600 tjackson@alcf.anl.gov

  18. Virginia Doyle | Argonne Leadership Computing Facility

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    Virginia

    Virginia Doyle Administrative Secretary Virginia Doyle Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 1D24 Argonne, IL 60439 630-252-0373 vdoyle@alcf.anl.gov

  19. Workbook Contents

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    Monthly","112015" ,"Release Date:","1292016" ,"Next Release Date:","2292016" ,"Excel File Name:","n3020il3m.xls" ,"Available from Web Page:","http:tonto.eia.govdnavng...

  20. SDE | Open Energy Information

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    search Name: SDE Address: 15A Lubetkin Street Place: Tel Aviv Zip: 67532 Region: Israel Sector: Marine and Hydrokinetic Phone Number: 972-37397107 Website: www.sde.co.il This...

  1. ALSNews Vol. 298

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    Weng, S. Chittaboina, R. Zhuo, P.M. Harrell, Y.T. Trinh, Q. Zhang, I.L. Urbatsch, and G. Chang, "Structure of P-glycoprotein reveals a molecular basis for poly-specific drug...

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    Raymond Loy Application Performance Engineer Ray Loy Argonne National Laboratory 9700 South Cass Avenue Building 240 - Rm. 1126 Argonne, IL 60439 630-252-7205 rloy@alcf.anl.gov Ray...

  6. Off-site Lodging (short-term) | Advanced Photon Source

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  7. Rural Electric Conven Coop | Open Energy Information

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    www.recc.coop Twitter: @RECCAuburnIL Facebook: https:www.facebook.comRECC.Auburn?refsearch&sid100000351831275.1405275847..1 Outage Hotline: (217) 438-6197 Outage Map:...

  8. QA Corporate Board Meeting - June 2010 | Department of Energy

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    June 2010 QA Corporate Board Meeting - June 2010 7th EM Quality Assurance Corporate Board Meeting Meeting Location: Marriott Chicago O'Hare, 8535 West Higgins Road, Chicago, IL...

  9. BPA-2014-00650-FOIA Response

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    Charles Patrick "Pat" Roberts (R-KS, 1997-present) The office of Congressman Brad Schneider (D-IL, 2013-present) The office of Congressman John Tierney (D-MA, 1997-present) We...

  10. This list does not imply DOE endorsement of the individuals or...

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    ... kbharbin@crimson.ua.edu 205-292-9369 AL Hart, Aaron 312-355-3445 IL Heffner, Craig ... 207-774-5961 ME Woodbury, Keith keith.woodbury@ua.edu 205-348-1647 AL ...

  12. Microsoft Word - Jeff_Miller_IACT

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    Miller Argonne National Laboratory Chemical Sciences and Engineering Division 9700 S. Cass Ave, Building 200 Argonne, IL 60429-4837 Phone: (630) 252-1928 E-mail: millerjt@anl.gov...

  13. CX-100485 Categorical Exclusion Determination

    Broader source: Energy.gov [DOE]

    Workforce Development for Hydropower Award Number: DE-EE0006507 CX(s) Applied: A9 Water Power Program Date: 02/27/2014 Location(s): IL Office(s): Golden Field Office

  14. City of Peru, Illinois (Utility Company) | Open Energy Information

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    Peru, Illinois (Utility Company) Jump to: navigation, search Name: City of Peru Place: Illinois Phone Number: 815-223-0044 Website: www.peru.il.uscity-directory Facebook: https:...

  15. B

    Office of Scientific and Technical Information (OSTI)

    ... Chicago, IL. Asphalt Institute, 1977. College Park, MD. Introduction to Asphalt and Some o f Its Uses, MS-5, Atkinson, R.J.C., 1956. Stonehenqe, H. Hamilton, London, England. ...

  16. Annual Report for SCC

    Office of Scientific and Technical Information (OSTI)

    ... and inhibit gas transport, a new class of ring-forming ILs was proposed. ... One main advantage of the phase change amino acid system lies in the potential to achieve ...

  17. RPT_PERIOD","R_S_NAME","LINE_NUM","PROD_CODE","PROD_NAME","PORT...

    U.S. Energy Information Administration (EIA) Indexed Site

    LLC ",275,"WOOD RIVER","IL","ILLINOIS",2 "applicationvnd.ms-excel","ATLANTIC TRADING MARKETING ",17,025,"Crude Oil",3401,"PEMBINA, ND","NORTH DAKOTA",2,260,"CANADA",68,0.25,22.42,...

  18. RPT_PERIOD","R_S_NAME","LINE_NUM","PROD_CODE","PROD_NAME","PORT...

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    LLC ",275,"WOOD RIVER","IL","ILLINOIS",2 "applicationvnd.ms-excel","ATLANTIC TRADING MARKETING ",3,025,"Crude Oil",3401,"PEMBINA, ND","NORTH DAKOTA",2,260,"CANADA",58,3.34,12.76,"...

  19. DOE - Office of Legacy Management -- Kankakee Ordnance Plant...

    Office of Legacy Management (LM)

    Also see Documents Related to KANKAKEE ORDNANCE PLANT IL.32-1 - DOE Memorandum; A.Williams to the File; Subject: Elimination of the Kankakee Ordnance Plant Site; August 12,...

  20. Workbook Contents

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    Annual",2014 ,"Release Date:","4292016" ,"Next Release Date:","5312016" ,"Excel File Name:","n9050il2a.xls" ,"Available from Web Page:","http:tonto.eia.govdnavnghist...