National Library of Energy BETA

Sample records for barter transactions involving

  1. GC GUIDANCE ON BARTER TRANSACTIONS INVOLVING DOE-OWNED URANIUM

    Energy Savers [EERE]

    GC GUIDANCE ON BARTER TRANSACTIONS INVOLVING DOE-OWNED URANIUM The Department of Energy has on a variety of occasions engaged in transactions under which it bartered uranium to which it has title for goods or services . This guidance memorializes the results of analyses previously directed to individual proposed transactions . For the reasons discussed below, we conclude that the Atomic Energy Act of 1954' , as amended, (AEA), authorizes such barter transactions. Background : DOE Barter

  2. GC GUIDANCE ON BARTER TRANSACTIONS INVOLVING DOE-OWNED URANIUM...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    results of analyses previously directed to individual proposed transactions . For the reasons discussed below, we conclude that the Atomic Energy Act of 1954' , as amended, (AEA),...

  3. OpenBarter | Open Energy Information

    Open Energy Info (EERE)

    Interface: Desktop Application, Website Website: olivierch.github.ioopenBarter Cost: Free OpenEI Keyword(s): International Language: English References: openbarter1...

  4. Memorandum, Reporting of Radiological Sealed Sources Transactions...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The requirements for reporting transactions involving radiological sealed sources are identified in Department of Energy (DOE) Notice (N) 234.1, Reporting of Radioactive Sealed ...

  5. Direct Research & Development Transactions | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Direct Research & Development Transactions Direct Research & Development Transactions DOE direct research and development transactions include contracts, grants, and cooperative ...

  6. Doubly Distributed Transactions

    Energy Science and Technology Software Center (OSTI)

    2014-08-25

    Doubly Distributed Transactions (D2T) offers a technique for managing operations from a set of parallel clients with a collection of distributed services. It detects and manages faults. Example code with a test harness is also provided

  7. Memorandum, Reporting of Radiological Sealed Sources Transactions

    Broader source: Energy.gov [DOE]

    The requirements for reporting transactions involving radiological sealed sources are identified in Department of Energy (DOE) Notice (N) 234.1, Reporting of Radioactive Sealed Sources. The data reported in accordance with DOE N 234.1 are maintained in the DOE Radiological Source Registry and Tracking (RSRT) database by the Office of Information Management, within the Office of Environment, Health, Safety and Security.

  8. Transactional Network Platform: Applications

    SciTech Connect (OSTI)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  9. Natural gas industry's response to transaction costs

    SciTech Connect (OSTI)

    Mulherin, J.H.

    1985-07-25

    Legislators and regulators have historically viewed the organizational features in the natural gas industry as noncompetitive. Challenging recent suggestions that the contractual arrangements in the industry are in violation of antitrust statutes, the author states that the methods of organization such as long-term contracts, take-or-pay provisions, and most-favored nation clauses are competitive responses to the costs of transacting in the natural gas industry. These arrangements lower transaction costs by mitigating the opportunistic behavior that can potentially arise in long-term relations involving specialized assets. If policymakers want to enable cost reductions in the industry to reduce the price burden felt by users of gas, an accompaniment of price decontrol by overall deregulation is in order.

  10. Transactional Network | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transactional Network Transactional Network Lead Performer: Pacific Northwest National Laboratory - Richland, WA Project Partners: -- Lawrence Berkeley National Laboratory - Berkeley, CA -- Oak Ridge National Laboratory - Oak Ridge, TN -- Transformative Wave - Kent, WA -- Emerson - St. Louis, MO -- NorthWrite - Minneapolis, MN -- EnerNOC - Baltimore, MD DOE Funding: $625,000 Cost Share: N/A Project website: http://transactionalnetwork.pnnl.gov/ Project Term: Jan. 2013 - 2016 Project Objective

  11. Residential Transactive Control Demonstration

    SciTech Connect (OSTI)

    Widergren, Steven E.; Fuller, Jason C.; Marinovici, Maria C.; Somani, Abhishek

    2014-02-19

    Arguably the most exciting aspect of the smart grid vision is the full participation of end-use resources with all forms of generation and energy storage in the reliable and efficient operation of an electric power system. Engaging all of these resources in a collaborative manner that respects the objectives of each resource, is sensitive to the system and local constraints of electricity flow, and scales to the large number of devices and systems participating is a grand challenge. Distributed decision-making system approaches have been presented and experimentation is underway. This paper reports on the preliminary findings of a residential demand response demonstration that uses the bidding transactions of supply and end-use air conditioning resources communicating with a real-time, 5 minute market to balance the various needs of the participants on a distribution feeder. The nature of the demonstration, the value streams being explored, and the operational scenarios implemented to characterize the system response are summarized along with preliminary findings.

  12. GridWise Transactive Energy Framework (DRAFT Version)

    SciTech Connect (OSTI)

    Melton, Ronald B.

    2013-11-06

    Over the past decade, the use of demand response and other flexible distributed resources for market efficiency and grid reliability has grown dramatically. Federal and state policy objectives point to an important role for customers loads, generation and storage in the management of an increasingly unpredictable power system. As we consider the need to substantially scale the use of flexible distributed energy resources, there has been growing attention to the need to address not only the economics, but also the control system implications to ensure grid reliability. This has led to a focus on an area of activity called Transactive Energy. Transactive Energy refers to the combination of economic and control techniques to improve grid reliability and efficiency. These techniques may also be used to optimize operations within a customers facility. The Department of Energy has supported the GridWise Architecture Council (the Council) in developing a conceptual framework that can be used in developing architectures, and designing solutions related to transactive energy. The goal of this effort is to encourage and facilitate collaboration among the many stakeholders involved in the transformation of the power system and thereby advance the practical implementation of transactive energy.

  13. Transactive energy: enabling a more intelligent, interactive...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    such as customer engagement, business and policy barriers, grid economics, the role of demand response, and cyber and physical security risks. But the transactive concept isn't...

  14. Technical Meeting: Software Framework for Transactive Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Grid Integration (Hagerman, DOE Building Technologies Office) PDF icon Presentation: Motivation for the Transaction-Based Reference Platform (Hernandez, PNNL) PDF icon ...

  15. Volttron (TM) Transactive Control Node: Case Study

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... LinuxPython implementation. TC Node: An implementation of Transactive Energy that uses ... platform for fast development - PythonLinux are effective and efficient - VOLTTRON ...

  16. Chapter 12 - Inter-Entity Transactions

    Broader source: Energy.gov (indexed) [DOE]

    INTER-ENTITY TRANSACTIONS 1. INTRODUCTION. a. Purpose. The chapter establishes the principles and procedures of financing and accounting for costs of work performed by one DOE...

  17. Transactions, Technology & Contractor Human Resources | Department...

    Broader source: Energy.gov (indexed) [DOE]

    Panel Technician | Credit: DOE Archives Solar Panel Technician | Credit: DOE Archives Offices of the Deputy General Counsel for Transactions, Technology, & Contractor Human...

  18. Demand Response (transactional control) - Energy Innovation Portal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Analysis Energy Analysis Electricity Transmission Electricity Transmission Find More Like This Return to Search Demand Response (transactional control) Pacific Northwest ...

  19. Quantifying the Level of Cross-State Renewable Energy Transactions...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Quantifying the Level of Cross-State Renewable Energy Transactions Quantifying the Level of Cross-State Renewable Energy Transactions This analysis provides first-ever assessment ...

  20. Capturing Energy Upgrades in the Real Estate Transaction | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Capturing Energy Upgrades in the Real Estate Transaction Capturing Energy Upgrades in the Real Estate Transaction Because green building techniques and products may impact the ...

  1. New Mexico Non-Taxable Transaction Certificate (NM NTTC) Request

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mexico Non-Taxable Transaction Certificate (NM NTTC) Request This form is for vendors of Los Alamos National Laboratory. To request a NM Non-Taxable Transaction Certificate (NTTC),...

  2. Motivation for the Transaction-Based Reference Platform

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Motivation for the Transaction-Based Reference Platform Or How I learned to Stop Worrying and Love Transactions George Hernandez Pacific Northwest National Lab July 23-24, 2015 ...

  3. Orange Button - Solar Bankability Data to Advance Transactions and Access

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    (SB-DATA) | Department of Energy Orange Button - Solar Bankability Data to Advance Transactions and Access (SB-DATA) Orange Button - Solar Bankability Data to Advance Transactions and Access (SB-DATA) Orange Button – Solar Bankability Data to Advance Transactions and Access (SB-DATA) Creating unified data standards will help the solar industry reduce market inefficiencies and lower costs for consumers. Orange Button, originally named Solar Bankability Data to Advance Transactions and

  4. Transactive Controls Overview - 2014 BTO Peer Review | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transactive Controls Overview - 2014 BTO Peer Review Transactive Controls Overview - 2014 BTO Peer Review Presenter: Joseph Hagerman, U.S. Department of Energy This presentation at the 2014 Peer Review provided an overview of the Building Technologies Office's Transactive Controls activities. Through robust feedback, the BTO Program Peer Review enhances existing efforts and improves future designs. View the Presentation PDF icon Transactive Controls Overview - 2014 BTO Peer Review More Documents

  5. Transactions, Technology and Contractor Human Relations | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Services » Transactions, Technology and Contractor Human Relations Transactions, Technology and Contractor Human Relations Transactions, Technology and Contractor Human Relations Offices of the Deputy General Counsel for Transactions, Technology and Contractor Human Resources Office of the Assistant General Counsel for Procurement and Financial Assistance (GC-61) Office of the Assistant General Counsel for Technology Transfer and Intellectual Property (GC-62) Office of the Assistant

  6. Automated Measurement and Signaling Systems for the Transactional Network |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Measurement and Signaling Systems for the Transactional Network Automated Measurement and Signaling Systems for the Transactional Network The Transactional Network Project is a multi-lab activity funded by the U.S. Department of Energy's Building Technologies Office. The project team included staff from Lawrence Berkeley National Laboratory, Pacific Northwest National Laboratory, and Oak Ridge National Laboratory. The team designed, prototyped, and tested a transactional

  7. System and method for secure group transactions

    DOE Patents [OSTI]

    Goldsmith, Steven Y.

    2006-04-25

    A method and a secure system, processing on one or more computers, provides a way to control a group transaction. The invention uses group consensus access control and multiple distributed secure agents in a network environment. Each secure agent can organize with the other secure agents to form a secure distributed agent collective.

  8. Creating a Transactive Energy Framework: Improving Reliability and Efficiency

    SciTech Connect (OSTI)

    Melton, Ronald B.

    2013-11-01

    The use of demand response and other flexible distributed resources over the past decade for market efficiency and grid reliability has grown dramatically. Federal and state policy objectives point to an important role for customer loads, generation and storage in the management of an increasingly unpredictable power system. As we consider the need to substantially scale the use of flexible distributed energy resources, there has been growing attention to the need to address not only the economics, but also the control system implications to ensure grid reliability. This has led to a focus on an area of activity called “Transactive Energy.” Transactive Energy refers to the combination of economic and control techniques that improve grid reliability and efficiency. These techniques may also be used to optimize operations within a customer’s facility. The Department of Energy has supported the GridWise® Architecture Council (“the Council”) to develop a framework to provide opportunity for collaboration among the many stakeholders involved in the transformation of the power system.

  9. Transaction-Based Building Controls Framework, Volume 1: Reference Guide

    SciTech Connect (OSTI)

    Somasundaram, Sriram; Pratt, Robert G.; Akyol, Bora A.; Fernandez, Nicholas; Foster, Nikolas AF; Katipamula, Srinivas; Mayhorn, Ebony T.; Somani, Abhishek; Steckley, Andrew C.; Taylor, Zachary T.

    2014-04-28

    This document proposes a framework concept to achieve the objectives of raising buildings efficiency and energy savings potential benefitting building owners and operators. We call it a transaction-based framework, wherein mutually-beneficial and cost-effective market-based transactions can be enabled between multiple players across different domains. Transaction-based building controls are one part of the transactional energy framework. While these controls realize benefits by enabling automatic, market-based intra-building efficiency optimizations, the transactional energy framework provides similar benefits using the same market -based structure, yet on a larger scale and beyond just buildings, to the society at large.

  10. Electricity transactions across international borders, 1986

    SciTech Connect (OSTI)

    Not Available

    1987-10-01

    This report summarizes the electricity exchanges between the United States and Mexico and Canada during Calendar Year 1986. The construction, connection, operation and maintenance of any electric transmission facility which crosses an international border of the United States requires a Presidential permit. Presidential permits require that an annual report be filed by the permit holder detailing all transactions with the foreign country. 3 figs., 3 tabs.

  11. SF 6432-IN International Commercial Transactions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Department Release Date: 11/17/15 Page 1 of 11 Printed copies of this document are uncontrolled. Retrieve latest version electronically. SANDIA CORPORATION SF 6432-IN (11/2015) SECTION II STANDARD TERMS AND CONDITIONS FOR INTERNATIONAL COMMERCIAL TRANSACTIONS THE FOLLOWING CLAUSES APPLY TO THIS CONTRACT AS INDICATED UNLESS SPECIFICALLY DELETED, OR EXCEPT TO THE EXTENT THEY ARE SPECIFICALLY SUPPLEMENTED OR AMENDED IN WRITING IN THE SIGNATURE PAGE OR SECTION I OF THIS CONTRACT. (CTRL+CLICK ON A

  12. SF 6432-IN International Commercial Transactions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IN (04/2015) SECTION II STANDARD TERMS AND CONDITIONS FOR INTERNATIONAL COMMERCIAL TRANSACTIONS THE FOLLOWING CLAUSES APPLY TO THIS CONTRACT AS INDICATED UNLESS SPECIFICALLY DELETED, OR EXCEPT TO THE EXTENT THEY ARE SPECIFICALLY SUPPLEMENTED OR AMENDED IN WRITING IN THE SIGNATURE PAGE OR SECTION I OF THIS CONTRACT. (CTRL+CLICK ON A LINK BELOW TO ADVANCE DIRECTLY TO THAT SECTION) ACCEPTANCE OF TERMS AND CONDITIONS APPLICABLE LAW ASSIGNMENT BANKRUPTCY CANCELLATION FOR DEFAULT CHANGES COMPLIANCE

  13. Framework for Address Cooperative Extended Transactions

    Energy Science and Technology Software Center (OSTI)

    1997-12-01

    The Framework for Addressing Cooperative Extended Transactions (FACET) is an object-oriented software framework for building models of complex, cooperative behaviors of agents. it can be used to implement simulation models of societal processes such as the complex interplay of participating individuals and organizations engaged in multiple concurrent transactions in pursuit of their various goals. These transactions can be patterned on, for example, clinical guidelines and procedures, business practices, government and corporate policies, etc. FACET canmore » also address other complex behaviors such as biological life cycles or manufacturing processes. FACET includes generic software objects representing the fundamental classes of agent -- Person and Organization - with mechanisms for resource management, including resolution of conflicting requests for participation and/or use of the agent's resources. The FACET infrastructure supports stochastic behavioral elements and coping mechanisms by which specified special conditions and events can cause an active cooperative process to be preempted, diverting the participants onto appropriate alternative behavioral pathways.« less

  14. Modeling an Application's Theoretical Minimum and Average Transactional Response Times

    SciTech Connect (OSTI)

    Paiz, Mary Rose

    2015-04-01

    The theoretical minimum transactional response time of an application serves as a ba- sis for the expected response time. The lower threshold for the minimum response time represents the minimum amount of time that the application should take to complete a transaction. Knowing the lower threshold is beneficial in detecting anomalies that are re- sults of unsuccessful transactions. On the converse, when an application's response time falls above an upper threshold, there is likely an anomaly in the application that is causing unusual performance issues in the transaction. This report explains how the non-stationary Generalized Extreme Value distribution is used to estimate the lower threshold of an ap- plication's daily minimum transactional response time. It also explains how the seasonal Autoregressive Integrated Moving Average time series model is used to estimate the upper threshold for an application's average transactional response time.

  15. Nature of Transactions (TI) Code | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    Nature of Transactions (TI) Code U.S. Department of Energy / U.S. Nuclear Regulatory Commission Nuclear Materials Management & Safeguards System Nature of Transactions (TI) Code* Nature of Transactions (TI) Code* Code: Description: A Initiates lease and financial responsibility of DOE-owned material B Transfer of lease and financial responsiblity of DOE-owned material C Transfer of DOE-owned material with no change in lease or financial responsibility D Return to DOE for credit under DOE

  16. Contacts for the Deputy General Counsel for Transactions, Technology, &

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Contractor Human Resources (GC-60) | Department of Energy Transactions, Technology, & Contractor Human Resources (GC-60) Contacts for the Deputy General Counsel for Transactions, Technology, & Contractor Human Resources (GC-60) Gena E. Cadieux, Deputy General Counsel for Transactions, Technology, & Contractor Human Resources 202-586-3426 gena.cadieux@hq.doe.gov Lisa N. Brown, Administrative Staff 202-586-5246 202-586-0325 (fax)

  17. Technical Meeting: Software Framework for Transactive Energy: VOLTTRON(tm)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2015 | Department of Energy Software Framework for Transactive Energy: VOLTTRON(tm) 2015 Technical Meeting: Software Framework for Transactive Energy: VOLTTRON(tm) 2015 On July 23 and 24, 2015, BTO held technical meetings graciously hosted by the Virginia Tech Advanced Research Institute on a Software Framework for Transactive Energy: VOLTTRON(tm). The purpose of this meeting was to provide an overview of the VOLTTRON platform, present new developments and uses, discuss advancement of the

  18. PV Paper Published in IEEE Transactions on Sustainable Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Paper Published in IEEE Transactions on Sustainable Energy - Sandia Energy Energy Search Icon ... Hydrogen Infrastructure Hydrogen Production Market Transformation Fuel Cells ...

  19. Automated Measurement and Signaling Systems for the Transactional...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    for Transactive Energy Technical Meeting: DataCommunication Standards and Interoperability of Building Appliances, Equipment, and Systems 2012 Load as a Resource Program Peer Review

  20. Technical Meeting on the Software Framework for Transactive Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Transactive energy in buildings will rely on robust control software that enables automatic, market-based intra-building efficiency optimizations. BTO believes that the best way to ...

  1. Contacts for the Deputy General Counsel for Transactions, Technology...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Gena E. Cadieux, Deputy General Counsel for Transactions, Technology, & Contractor Human Resources 202-586-3426 gena.cadieux@hq.doe.gov Lisa N. Brown, Administrative Staff ...

  2. IEEE TRANSACTIONS ON PLASMA SCIENCE, VOL.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8 IEEE TRANSACTIONS ON PLASMA SCIENCE, VOL. 33, NO. 2, APRIL 2005 Imaging of a Double Helical Structure in the Reversed Field Pinch F. Bonomo, B. E. Chapman, P. Franz, L. Marrelli, P. Martin, P. Piovesan, I. Predebon, G. Spizzo, and R. B. White Abstract-X-ray tomography and Poincaré reconstructions with the ORBIT code allow imaging of coherent structures emerging in a magnetized fusion plasma when chaos in the magnetic field is reduced. Index Terms-Magnetohydrodynamic (MHD), Monte Carlo

  3. Systems and methods for performing wireless financial transactions

    DOE Patents [OSTI]

    McCown, Steven Harvey

    2012-07-03

    A secure computing module (SCM) is configured for connection with a host device. The SCM includes a processor for performing secure processing operations, a host interface for coupling the processor to the host device, and a memory connected to the processor wherein the processor logically isolates at least some of the memory from access by the host device. The SCM also includes a proximate-field wireless communicator connected to the processor to communicate with another SCM associated with another host device. The SCM generates a secure digital signature for a financial transaction package and communicates the package and the signature to the other SCM using the proximate-field wireless communicator. Financial transactions are performed from person to person using the secure digital signature of each person's SCM and possibly message encryption. The digital signatures and transaction details are communicated to appropriate financial organizations to authenticate the transaction parties and complete the transaction.

  4. Transaction-Based Controls for Building-Grid Integration: VOLTTRON™

    SciTech Connect (OSTI)

    Akyol, Bora A.; Haack, Jereme N.; Hernandez, George; Katipamula, Srinivas; Widergren, Steven E.

    2015-07-01

    The U.S. Department of Energy’s (DOE’s) Building Technologies Office (BTO) is supporting the development of a “transactional network” concept that supports energy, operational, and financial transactions between building systems (e.g., rooftop units -- RTUs), and the electric power grid using applications, or 'agents', that reside either on the equipment, on local building controllers, or in the Cloud. The transactional network vision is delivered using a real-time, scalable reference platform called VOLTTRON that supports the needs of the changing energy system. VOLTTRON is an agent execution and an innovative distributed control and sensing software platform that supports modern control strategies, including agent-based and transaction-based controls. It enables mobile and stationary software agents to perform information gathering, processing, and control actions.

  5. VOLTTRON Lite: Integration Platform for the Transactional Network

    SciTech Connect (OSTI)

    Haack, Jereme N.; Katipamula, Srinivas; Akyol, Bora A.; Lutes, Robert G.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform. The platform is intended to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop units (RTUs) and the electric grid using applications or “agents” that reside on the platform, on the equipment, on local building controller or in the Cloud. This document describes the core of the transactional network platform, the Volttron Lite™ software and associated services hosted on the platform. Future enhancements are also discussed. The appendix of the document provides examples of how to use the various services hosted on the platform.

  6. Acquisition Guide, Chapter 38.1, Strategic Acquisition Transactions...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    See the Recovery Act Guide for those requirements at http:management.energy.govpolicyguidance1672.htm. PDF icon PF2010-24 AG 38.1 Strategic Acquisition Transactions A Guide ...

  7. Capturing Energy Efficiency Upgrades in the Real Estate Transaction

    Broader source: Energy.gov [DOE]

    "Capturing Energy Efficiency Upgrades in the Real Estate Transaction," by Residential Energy Efficiency Solutions, July 10, 2012. Describes the concept of a residential MPG number as a simple way of describing a home’s energy consumption.

  8. 17.1 - Interagency Acquisitions, Interagency Transactions, and Interagency Agreements

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    17.1 (June 2012) 1 Interagency Acquisitions, Interagency Transactions, and Interagency Agreements CONTENTS Guiding Principles  This chapter provides guidance on interagency acquisitions, interagency transactions and interagency agreements  In addition to interagency acquisitions authorized by the Economy Act, Federal Acquisition Regulation (FAR) 17.5 is revised to broaden the scope of coverage to address all Interagency Acquisitions to include orders over $500,000 issued against Federal

  9. 2012 Fuel Cycle Technologies Annual Review Meeting Transaction Report |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy 2 Fuel Cycle Technologies Annual Review Meeting Transaction Report 2012 Fuel Cycle Technologies Annual Review Meeting Transaction Report The United States must continue to ensure improvements and access to this technology so we can meet our economic, environmental and energy security goals. We rely on nuclear energy because it provides a consistent, reliable and stable source of base load electricity with an excellent safety record in the United States. In order to

  10. Ontological leveling and elicitation for complex industrial transactions

    SciTech Connect (OSTI)

    Phillips, L.R.; Goldsmith, S.Y.; Spires, S.V.

    1998-11-01

    The authors present an agent-oriented mechanism that uses a central ontology as a means to conduct complex distributed transactions. This is done by instantiating a template object motivated solely by the ontology, then automatically and explicitly linking each temple element to an independently constructed interface component. Validation information is attached directly to the links so that the agent need not know a priori the semantics of data validity, merely how to execute a general validation process to satisfy the conditions given in the link. Ontological leveling is critical: all terms presented to informants must be semantically coherent within the central ontology. To illustrate this approach in an industrial setting, they discuss an existing implementation that conducted international commercial transactions on the World-Wide Web. Agents operating within a federated architecture construct, populate by Web-based elicitation, and manipulate a distributed composite transaction object to effect transport of goods over the US/Mexico border.

  11. New Mexico Non-Taxable Transaction Certificate (NM NTTC) Request

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mexico Non-Taxable Transaction Certificate (NM NTTC) Request This form is for vendors of Los Alamos National Laboratory. To request a NM Non-Taxable Transaction Certificate (NTTC), please provide the information requested below. Request can be submitted by mail, email or fax to: Los Alamos National Laboratory P.O. Box 1663 Accounts Payable, MS P240 Los Alamos, NM 87545 Fax: (505) 665-8357 processsupport@lanl.gov Company Name (as registered with Tax Authority) NOTE: If registered with the State

  12. Method and apparatus for managing transactions with connected computers

    DOE Patents [OSTI]

    Goldsmith, Steven Y.; Phillips, Laurence R.; Spires, Shannon V.

    2003-01-01

    The present invention provides a method and apparatus that make use of existing computer and communication resources and that reduce the errors and delays common to complex transactions such as international shipping. The present invention comprises an agent-based collaborative work environment that assists geographically distributed commercial and government users in the management of complex transactions such as the transshipment of goods across the U.S.-Mexico border. Software agents can mediate the creation, validation and secure sharing of shipment information and regulatory documentation over the Internet, using the World-Wide Web to interface with human users.

  13. Interim Guidance on DOE Personal Property Foreign Transactions

    Broader source: Energy.gov [DOE]

    The attached Acquisition Letter provides interim direction and procedural guidance to DOE and NNSA on proper protocol for personal property transactions executed with foreign entities, to include property title transfers, loans and abandonments and pertains to personal property in the hand of the Federal government, contractor or a third party. Direction and guidance is specific to accountable personal property, as defined in DOE Order 580.1. Guidance in this Acquisition Letter shall be followed until DOE Order 580.1 is updated to include foreign transactions.

  14. Political Activity at DOE Facilities by DOE Contractors | Department of

    Office of Environmental Management (EM)

    Policy_Statement_on_TT.pdf Policy_Statement_on_TT.pdf PDF icon Policy_Statement_on_TT.pdf More Documents & Publications Policy_Statement_on_Technology_Transfer.pdf Chapter 17 - Special Contracting Methods GC GUIDANCE ON BARTER TRANSACTIONS INVOLVING DOE-OWNED URANIUM Energy

    Activity at DOE Facilities by DOE Contractors Political Activity at DOE Facilities by DOE Contractors The attached guidance is issued to Contracting Officers to remind them of restrictions on political activity by

  15. Transactive Controls R&D — 2016 BTO Peer Review

    Broader source: Energy.gov [DOE]

    This presentation at the 2016 Peer Review provided an overview of the Building Technologies Office’s Transactive Controls R&D (Tx-R&D) Program. Through robust feedback, the BTO Program Peer Review enhances existing efforts and improves future designs.

  16. Automated Measurement and Signaling Systems for the Transactional Network

    SciTech Connect (OSTI)

    Piette, Mary Ann; Brown, Richard; Price, Phillip; Page, Janie; Granderson, Jessica; Riess, David; Czarnecki, Stephen; Ghatikar, Girish; Lanzisera, Steven

    2013-12-31

    The Transactional Network Project is a multi-lab activity funded by the US Department of Energy?s Building Technologies Office. The project team included staff from Lawrence Berkeley National Laboratory, Pacific Northwest National Laboratory and Oak Ridge National Laboratory. The team designed, prototyped and tested a transactional network (TN) platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). PNNL was responsible for the development of the TN platform, with agents for this platform developed by each of the three labs. LBNL contributed applications to measure the whole-building electric load response to various changes in building operations, particularly energy efficiency improvements and demand response events. We also provide a demand response signaling agent and an agent for cost savings analysis. LBNL and PNNL demonstrated actual transactions between packaged rooftop units and the electric grid using the platform and selected agents. This document describes the agents and applications developed by the LBNL team, and associated tests of the applications.

  17. Capturing and using precise semantics for complex transactions

    SciTech Connect (OSTI)

    Phillips, L.R.; Goldsmith, S.Y.; Spires, S.V.

    1998-08-01

    In this paper the authors discuss the leveling process by which a business process ontology is formed in a distributed, multi-lingual, multi-stakeholder environment, with attention to realizing elicitation mechanisms that maintain registration of users` terms with the common ontology. Business processes are recognized from use-case analysis, specified in terms of the common ontology, and realized as operations on the components of a transaction: a temporally extended, complex, distributed object. A primary advantage of this approach is that users see private terminologies while the transaction object is specified in terms of the common ontology, and registration between the two is automatic and continuous. Ready realization of multiple interfaces to stakeholders, independently constructed validation and verification mechanisms, distributed data, and a standard elicitation mechanism and process are other advantages. The language formation process was used successfully during the development of the Border Trade Facilitation System, an agent-oriented mechanism that conducts international border-crossing transactions. In this implementation, agents operating within a federated architecture construct, populate, verify, certify, and manipulate a distributed composite transaction object to effect transport of goods over the US/Mexico border.

  18. Customer Engagement in AEP gridSMART Residential Transactive System

    SciTech Connect (OSTI)

    Widergren, Steven E.; Marinovici, Maria C.; Fuller, Jason C.; Subbarao, Krishnappa; Chassin, David P.; Somani, Abhishek

    2014-12-31

    — In 2013, AEP Ohio (AEP) operated a 5-minute real-time price (RTP) electricity market system on 4 distribution feeders as part of their gridSMART® demonstration project. The RTP households were billed for their electricity usage according to an RTP tariff approved by the Public Utility Commission of Ohio. They were given the incentive that their annual bill would be no greater than if they were on the flat-rate tariff, but they had financial incentives to shift consumption from high price periods to low price periods. Incentives were also available for response under high prices from local events, such as reaching the distribution feeder capacity or a critical peak pricing event. An analysis of this transactive system experiment was completed in early 2014. This paper describes the incentive provided to the customer, the nature of their interaction with the smart thermostat that provided automated response to the transactive signal, and their level of satisfaction with the program.

  19. DOE Issues Guidance for "Other Transactions" | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Guidance for "Other Transactions" DOE Issues Guidance for "Other Transactions" November 15, 2005 - 12:42pm Addthis Provides Opportunity for Increased Industry Research Partnerships WASHINGTON, DC - On November 7, 2005, the Department of Energy (DOE) issued an interim final rule for the establishment of policies and procedures for a new "other transaction" authority. This authority allows DOE to remove barriers to commercial firms' participation in some of DOE's

  20. Quantifying the Level of Cross-State Renewable Energy Transactions

    Broader source: Energy.gov [DOE]

    This analysis provides first-ever assessment of the extent to which renewable energy is crossing state borders to be used to meet renewable portfolio standard (RPS) requirements. Two primary methods for data collection are Renewable Energy Certificate (REC) tracking and power flow estimates. Data from regional REC tracking systems, state agencies, and utility compliance reports help understand how cross-state transactions have been used to meet RPS compliance. Data on regional renewable energy flow use generator-specific information primarily sourced from EIA, SNL Energy, and FERC Form 1 filings. The renewable energy examined through this method may or may not have actually been used to meet RPS compliance.

  1. Waste status and transaction record summary for the northwest quadrant of the Hanford 200 Area

    SciTech Connect (OSTI)

    Agnew, S.F.; Corbin, R.A.; Duran, T.B.; Jurgensen, K.A.; Ortiz, T.P.; Young, B.L.

    1995-09-01

    This supporting document contains a database of waste transactions and waste status reports for all the waste tanks in the northwest quadrant of the 200 West Area of the Hanford Site.

  2. An ANFIS-based on B2C electronic commerce transaction

    SciTech Connect (OSTI)

    Lin, Juan; Liu, Chenlian; Guo, Yongning

    2014-10-06

    The purpose of this study is to use an adaptive-network-based fuzzy inference system to model a fuzzy logic-based system (FIS) for supporting decision-making process in B2C electronic commerce transaction. Firstly we introduce FIS in B2C electronic commerce transaction and ANFIS. Then we use ANFIS to model FIS with different membership functions(MF). Lastly we give a conclusion.

  3. Challenges and Opportunities for Transactive Control of Electric Vehicle Supply Equipment. A Reference Guide

    SciTech Connect (OSTI)

    Jin, Xin; Meintz, Andrew

    2015-07-29

    This report seeks to characterize the opportunities and challenges that arise in developing a transactive control strategy for grid-EVSE integration in various use-case scenarios in a way that provides end-user, energy market, grid, and societal benefits. A detailed review provides information about EVSE integration market trends and stakeholder activities. This is followed by an exploration of value proposition for transactive control of EVSE at both the home scale and the building/campus scale. This report will serve as a reference guide for stakeholders in the grid-EVSE integration area, illustrate potential implementations, and identify a high-value research project for overcoming the barriers and unlocking the benefits of transactive controls of EVSE. While it is not intended to specify the technical details of the transactive control solution, the report contains a list of use cases describing potential applications of transactive control of EVSE, barriers to implementing these applications, and research and development (R&D) opportunities to overcome the barriers. The use cases of transactive control of EVSE are listed in Table ES1.

  4. Bartering results in cost savings | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Technology Park (old K-25 site) with EMWMF. The new roadway is part of a plan to ... UCOR illustrates that efforts to find new cost-saving solutions continue to ensure the ...

  5. Commitment to Public Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Create a Sustainable Future Commitment to Public Involvement Commitment to Public Involvement LANL is committed to our neighbors August 1, 2013 Lab Director McMillan talks with...

  6. Transactive Control and Coordination of Distributed Assets for Ancillary Services

    SciTech Connect (OSTI)

    Subbarao, Krishnappa; Fuller, Jason C.; Kalsi, Karanjit; Somani, Abhishek; Pratt, Robert G.; Widergren, Steven E.; Chassin, David P.

    2013-09-18

    The need to diversify energy supplies, the need to mitigate energy-related environmental impact, and the entry of electric vehicles in large numbers present challenges and opportunities to power system professionals. Wind and solar power provide many benefits, and to reap the benefits the resulting increased variabilityforecasted as well as unforecastedshould be addressed. Demand resources are receiving increasing attention as one means of providing the grid balancing services. Control and coordination of a large number (~millions) of distributed smart grid assets requires innovative approaches. One such is transactive control and coordination (TC2)a distributed, agent-based incentive and control system. The TC2 paradigm is to create a market system with the following characteristics: Participation should be entirely voluntary. The participant decides at what price s/he is willing to participate. The bids and responses are automated. Such an approach has been developed and demonstrated by Pacific Northwest National Laboratory for energy markets. It is the purpose of this project to develop a similar approach for ancillary services. In this report, the following ancillary services are considered: spinning reserve ramping regulation. These services are to be provided by the following devices: refrigerators water heaters clothes dryers variable speed drives. The important results are summarized below: The regulation signal can be divided into an energy-neutral high frequency component and a low frequency component. The high frequency component is particularly well suited for demand resources. The low frequency component, which carries energy non-neutrality, can be handled by a combination of generators and demand resources. An explicit method for such a separation is obtained from an exponentially weighted moving average filter. Causal filters (i.e., filters that process only present and past values of a signal) introduce delays that can be issues in some signal processing applications that treat the high frequency part as a noise to be eliminated. For regulation, the high frequency component is an essential part of the signal. The delay in the low frequency component is not a problem. A stochastic self-dispatch algorithm determines the response of the devices to the regulation signal. In an ensemble of devices under normal operation, some devices turn on and some turn off in any time interval. Demand response necessitates turning off devices that would normally be on, or turning on devices that would normally be off. Over time, some of these would have turned off on their own. A formalism to determine expectation values under a combination of natural and forced attrition has been developed. This formalism provides a mechanism for accomplishing a desired power profile within a bid period. In particular, a method to minimize regulation requirement can be developed. The formulation provides valuable insights into control. Some ancillary servicesramping to absorb unforecasted increase in renewable generation, and regulation downrequire the demand resources to increase their energy use. Some resources such as HVAC systems can do this readily, whereas some others require enabling technology. Even without such technology, it is possible to arrange refrigerators and water heaters to have an energy debt and be ready to increase their energy use. A transactive bid mechanism of revolving debt can be developed for this purpose. Dramatic changes in control systems, architecture and markets are expected in the electrical grid. The technical capabilities of a large number of devices interacting with the grid are changing. While it is too early to describe complete solutions, TC2 has attractive features suitable for adapting to the changes. The analyses in this report and the activities planned for FY 14 and beyond are designed to facilitate this transition.

  7. Temporary Waiver of Mandatory Use of the Strategic Integrated Procurement Enterprise System (STRIPES) for Certain Purchase Card Transactions

    Broader source: Energy.gov [DOE]

    Several issues have been identified relating to the use of STRIPES for the processing of transactions at or below the micro-purchase threshold of $3,000 using the Government-wide purchase card. These issues relate strictly to the efficient processing of such transactions and not to the ability of STRIPES to properly and accurately process these actions.

  8. Temporary Waiver of Mandatory Use of Strategic Integrated Procurement Enterprise System (STRIPES) for Certain Purchase Card Transactions

    Broader source: Energy.gov [DOE]

    Several issues have been identified relating to the use of STRIPES for the processing of transactions at or below the micro-purchase threshold of $3,000 using the Government-wide purchase card. This issues relate strictly to the efficient processing of such transactions and not to the ability of STRIPES to properly and accurately process these actions.

  9. Technical Meeting: Reference Guide for a Transaction-Based Building Controls Framework

    Broader source: Energy.gov [DOE]

    BTO held a technical meeting at NREL, in Golden, CO, to discuss BTO's vision for a transaction-rich buildings energy ecosystem that will unlock the energy efficiency and grid services values and deliver them to consumers. View the presentations and meeting notes.

  10. Transactive Controls R&D Overview — 2016 BTO Peer Review

    Broader source: Energy.gov [DOE]

    This presentation at the 2016 Peer Review provided an overview of the Building Technologies Office’s Transactive Controls R&D (Tx-R&D) Program. Through robust feedback, the BTO Program Peer Review enhances existing efforts and improves future designs.

  11. Transaction-based building controls framework, Volume 2: Platform descriptive model and requirements

    SciTech Connect (OSTI)

    Akyol, Bora A.; Haack, Jereme N.; Carpenter, Brandon J.; Katipamula, Srinivas; Lutes, Robert G.; Hernandez, George

    2015-07-31

    Transaction-based Building Controls (TBC) offer a control systems platform that provides an agent execution environment that meets the growing requirements for security, resource utilization, and reliability. This report outlines the requirements for a platform to meet these needs and describes an illustrative/exemplary implementation.

  12. Extension of Other Transaction Authority to enter into Technology Investment Agreements (TIAs)

    Broader source: Energy.gov [DOE]

    Section 3118 of the National Defense Authorization Act (NDAA) of 2011, Public Law 111-383, enacted January 7, 2011, has extended, through September 30, 2015, the "Other Transaction Authority" provision of the Act, which will allow the Department of Energy (DOE) to continue to use other types of agreements, other than grants or contracts, to carry out certain research projects.

  13. Quantifying the Level of Cross-State Renewable Energy Transactions (Presentation)

    SciTech Connect (OSTI)

    Heeter, J.; Beiter, P.; Flores, F.; Hurlbut, D.; Liu, C.

    2015-02-01

    This presentation and associated spreadsheet examine the level of cross-state renewable energy transactions. Most state renewable portfolio standard (RPS) policies allow for out-of-state renewable energy or renewable energy certificates to count towards compliance. This analysis focuses on compliance for 2012 and provides stakeholders with an understanding of the extent to which RPSs are being met.

  14. TPA Public Involvement Survey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hanford Tri-Party Agencies' Annual Public Involvement Survey Activities for Calendar Year 2008 Nolan Curtis Washington State Department of Ecology Nuclear Waste Program August 5,...

  15. Transacting generation attributes across market boundaries: Compatible information systems and the treatment of imports and exports

    SciTech Connect (OSTI)

    Grace, Robert; Wiser, Ryan

    2002-11-01

    Voluntary markets for ''green'' power, and mandatory policies such as fuel source disclosure requirements and renewables portfolio standards, each rely on the ability to differentiate electricity by the ''attributes'' of the generation. Throughout North America, electricity markets are devising accounting and verification systems for generation ''attributes'': those characteristics of a power plant's production such as fuel source and emissions that differentiate it from undifferentiated (or ''commodity'') electricity. These accounting and verification systems are intended to verify compliance with market mandates, create accurate disclosure labels, substantiate green power claims, and support emissions markets. Simultaneously, interest is growing in transacting (importing or exporting) generation attributes across electricity market borders, with or without associated electricity. Cross-border renewable attribute transactions have advantages and disadvantages. Broad access to markets may encourage more renewable generation at lower cost, but this result may conflict with desires to assure that at least some renewable resources are built locally to achieve either local policy goals or purchaser objectives. This report is intended to serve as a resource document for those interested in and struggling with cross-border renewable attribute transactions. The report assesses the circumstances under which renewable generation attributes from a ''source'' region might be recognized in a ''sink'' region. The report identifies several distinct approaches that might be used to account for and verify attribute import and export transactions, and assesses the suitability of these alternative approaches. Because policymakers have often made systems ''compatibility'' between market areas a pre-requisite to allowing cross-border renewable transactions, this report develops criteria for ''compatible information systems.'' Where fully compatible information systems do not exist, certain cross-border attribute transactions may still be deemed suitably credible and verifiable to be recognized; this report also identifies possible criteria for such ''compatible transactions.'' The importance of credibly addressing imports and exports of renewable energy attributes should be evident. A lack of clarity as to what generation can and cannot be recognized in various markets can paralyze investment in and contracting for renewable generation. The development of rules for imports and exports will also minimize the potential for ''double counting'' of renewable energy attributes, will help define where and at what cost renewable plants will be built, and will directly impact the location of the benefits that renewable generation provides. This report ultimately concludes that the ''correct'' approach to treating renewable energy imports and exports depends on the context and motivations behind the transaction or the mandate, and that the presence of practical constraints or multiple objectives of ten make selecting the best approach difficult. That said, the report urges those creating market rules to move quickly in defining valid cross-border transaction structures and to consider the implications of their decisions on the creation of viable markets for new renewable generation.

  16. The Department of Energy has opted to utilize the following agreement for Designated Non-Proprietary User Facilities transactions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    agreement for Designated Proprietary User Facilities transactions. Because these transactions are widespread across Departmental facilities, uniformity in agreement terms is desirable. Except for the *** provisions, minor modifications to the terms of this agreement may be made by CONTRACTOR, but any changes to the *** provisions or substantive changes to the non *** provisons will require approval by the DOE Contracting Officer, WHICH WILL LIKEY DELAY YOUR ACCESS TO THE USER FACILITY. In

  17. Acquisition Guide, Chapter 38.1, Strategic Acquisition Transactions: A Guide for

    Broader source: Energy.gov [DOE]

    The Strategic Acquisition Transactions Guide has been updated to reflect changes in the Federal Acquisition Regulation through Federal Acquisition Circular 2005-38 and other technical and editorial changes. A summary of these changes is provided on page three of the attached Guide. This Guide does not include the additional requirements required for orders funded under the Recovery Act. See the Recovery Act Guide for those requirements at http://management.energy.gov/policy~guidance/1672.htm.

  18. Commitment to Public Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Create a Sustainable Future » Commitment to Public Involvement Commitment to Public Involvement LANL is committed to our neighbors August 1, 2013 Lab Director McMillan talks with Lab historian Ellen McGhee during Lab tour Lab Director McMillan talks with Lab historian Ellen McGhee during Lab tour RELATED IMAGES http://farm4.staticflickr.com/3815/9442115459_390e5bc841_t.jpg Enlarge http://farm8.staticflickr.com/7111/7650961650_ed1571174f_t.jpg Enlarge

  19. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Public Involvement and Communication Committee Chair 1 : Liz Mattson 4 , Member Vice Chair 1 : Shannon Cram, Member Committee Members 2 : Shelley Cimon Liz Mattson Alissa Cordner Ken Niles Shannon Cram Ed Pacheco Rob Davis Dan Serres Tom Galioto Jean Vanni Floyd Hodges Steve White Paige Knight Unofficial Committee Members or Other Interested Parties 3 : Earl Fordham Gerry Pollet Paige Knight Steve Hudson 4 Susan Leckband 4 Facilitator: Cathy McCague 4 Agency & Technical Support: Kris Holmes

  20. 741 Transaction

    National Nuclear Security Administration (NNSA)

    using electronic formats DISCLAIMER This report was prepared as an account of work ......... 62 Material Balance Report Detail Information (Data Code 3 & 4) ...

  1. 741 Transaction

    National Nuclear Security Administration (NNSA)

    Data Input for DOE Contractors D-23 NMMSS welcomes comments and suggestions on the quality and usefulness of this publication. Your input is an important part of the...

  2. 741 Transaction

    National Nuclear Security Administration (NNSA)

    required to report government owned material to NMMSS should refer to the D-23, Personal Computer Data Input for Department of Energy Contractors for guidance in the electronic...

  3. 741 Transaction

    National Nuclear Security Administration (NNSA)

    D-23 Personal Computer Data Input for Department Of Energy Contractors Effective Date ... Germantown Building U.S. Department of Energy 1000 Independence Avenue, SW Washington, ...

  4. 741 Transaction

    National Nuclear Security Administration (NNSA)

    D-24 Personal Computer Data Input for Nuclear Regulatory Commission Licensees Effective Date January 1, 2012 A booklet of guidance for data submissions to NMMSS using electronic formats DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, make any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy,

  5. 741 Transaction

    National Nuclear Security Administration (NNSA)

    D-23 Personal Computer Data Input for Department Of Energy Contractors Effective Date January 1, 2012 A booklet of guidance for data submissions to NMMSS using electronic formats DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, make any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy,

  6. Public Involvement and Communications Committee:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    purposes only 09.08.15 Excerpt from the HAB Process Manual January 2012 Public Involvement and Communications Committee: Develops Board Advice for the TPA agencies on the...

  7. Public Involvement Committee - Transcribed Flipcharts

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    September 3, 2014 Public Involvement Opportunities * Review of PI materials and agency websites, listservs (use of and purpose of notifications). * CD process - approach to PI...

  8. Public Involvement Committee - Transcribed Flipcharts

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    education materials, including web materials * Evaluate effectiveness of TPA public involvement activities. Page 5 FY2015 Work Plan Ideas * Share innovative approaches to public...

  9. Acquisition Guide Chapter 17.1 – Interagency Acquisitions, Interagency Transactions, and Interagency Agreements – Minor Revision

    Broader source: Energy.gov [DOE]

    Acquisition Guide Chapter 17.1 – Interagency Acquisitions, Interagency transactions, and Interagency Agreements is revised to add under the paragraph C Exclusions that Power Marketing Administration's activities performed under its power marketing authority, policies, and procedures are excluded from this DOE Acquisition Guide Chapter. The revised chapter is attached with this flash. All other attachments from Policy Flash 2012-32 remain the same.

  10. Public Involvment Plan - Rifle, Colorado

    Office of Legacy Management (LM)

    4-TAR MAC-GWRIF 7.1 UMTRA Ground Water Project Public Involvement Plan for the Environmental Assessment of Ground Water Compliance at the New and Old Rifle, Colorado, Uranium Mill Tailings Sites May 1999 Prepared by U.S. Department of Energy Grand Junction Office Grand Junction, Colorado Work performed under DOE Contract No. DE-AC13-96GJ87335 Public Involvement Plan for the Rifle UMTRA Sites Page 2 Introduction This Public Involvement Plan is tiered to the Uranium Mill Tailings Remedial Action

  11. Field Experience with and Potential for Multi-time Scale Grid Transactions from Responsive Commercial Buildings

    SciTech Connect (OSTI)

    Piette, Mary Ann; Kiliccote, Sila; Ghatikar, Girish

    2014-08-01

    The need for and concepts behind demand response are evolving. As the electric system changes with more intermittent renewable electric supply systems, there is a need to allow buildings to provide more flexible demand. This paper presents results from field studies and pilots, as well as engineering estimates of the potential capabilities of fast load responsiveness in commercial buildings. We present a sector wide analysis of flexible loads in commercial buildings, which was conducted to improve resource planning and determine which loads to evaluate in future demonstrations. These systems provide important capabilities for future transactional systems. The field analysis is based on results from California, plus projects in the northwest and east coast. End-uses considered include heating, ventilation, air conditioning and lighting. The timescales of control include day-ahead, as well as day-of, 10-minute ahead and even faster response. This technology can provide DR signals on different times scales to interact with responsive building loads. We describe the latency of the control systems in the building and the round trip communications with the wholesale grid operators.

  12. Appendix V Public Involvement Plan

    Office of Legacy Management (LM)

    V Public Involvement Plan Revision No.: 6 February 2008 Federal Facility Agreement and Consent Order (FFACO) FFACO, Appendix V February 2008 i FFACO Public Involvement Plan U.S. Department of Energy National Nuclear Security Administration Nevada Site Office Las Vegas, Nevada U.S. Department of Defense Defense Threat Reduction Agency Detachment 1, Nevada Operations Mercury, Nevada U.S. Department of Energy Office of Legacy Management Grand Junction, Colorado FFACO, Appendix V February 2008 ii

  13. Public Involvement Committee - Transcribed Flipcharts

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    December 10, 2013 100-F 1. Public involvement/mtg in March - How to sequence Board Review with public comment period * Path 1: Could request comment period extension * Path 2: Could request HAB comments considered post comment period * If comment period starts in March, HAB could request to comment in May (advice) Page 1 What might be topics for policy-level discussions? What might be ways, other than meetings, to solicit involvement? What might be useful to present at March Board mtg? Page 2

  14. NEPA analysis of US-Canadian power transactions under the Columbia River Treaty

    SciTech Connect (OSTI)

    Pierce, K.S.; Weintraub, N.H.; Linehan, A.O.

    1995-12-01

    The Columbia River Treaty of 1961 led to the development of three hydroelectric projects on the Columbia River in Canada and one in the United States. Canada sold its share of the downstream power generation benefits of these facilities to US utilities for 30 years. The administrator of the Bonneville Power Administration (BPA) of the US Department of Energy is the {open_quotes}United States Entity{close_quotes} under the Columbia River Treaty with Canada. BPA prepared the {open_quotes}Delivery of the Canadian Entitlement{close_quotes} Environmental Impact Statement (EIS) to evaluate alternative means for the US to return to Canada the Canadian share of the downstream benefits when these 30-year agreements expire. Alternatives on both sides of the US-Canada border included new high-voltage transmission lines; new generating and conservation resources; and power sales, exchanges, and other transactions. BPA developed an EIS methodology and graphical representation technique for comparing the diverse options associated with the Delivery of the Canadian Entitlement that were instrumental in helping managers understand the impacts of alternatives in a timely manner. A graphical, modular approach helped convey complex relationships in ways that were easy to read and understand. In addition, analysis of potential environmental impacts in Canada was developed in order to provide relevant information to US decision-makers, without compromising the Canadian environmental review process. As a result, environmental analysis was fully integrated into the decision process. The EIS approach used in this project has become a prototype for other Department of Energy NEPA documents, both site-specific and programmatic.

  15. Profiles of foreign direct investment in US energy, 1991. [Contains a table of completed foreign direct investment transactions for 1991

    SciTech Connect (OSTI)

    Not Available

    1993-04-01

    Profiles of Foreign Direct Investment in US Energy 1991 describes the role of foreign ownership in US energy enterprises, with respect to investment, energy operations, and financial performance. Additionally, since energy investments are made in a global context, outward investment in energy is reviewed trough an examination of US-based companies' patterns of investment in foreign petroleum. The data used in this report come from the Energy Information Administration (EIA), the US Department of Commerce, company annual reports, and public disclosures of investment transactions.

  16. HOW YOU CAN BE INVOLVED

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    HOW YOU CAN BE INVOLVED www.youtube.com/hanfordsite www.twitter.com/hanfordsite www.facebook.com/hanfordsite The Hanford Site sits on 586-square-miles of shrub-steppe desert in southeastern Washington state. The site was created in 1943 as part of the Manhattan Project to produce plutonium for nuclear weapons. Between 1943 and 1963, nine nuclear reactors were built along the banks of the Columbia River. By 1988, all nine reactors were shut down. The weapons material production mission ended in

  17. Public Involvement and Communications Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8, 2012 FINAL MEETING SUMMARY HANFORD ADVISORY BOARD PUBLIC INVOLVEMENT & COMMUNICATIONS COMMITTEE MEETING February 8, 2012 Richland, WA Topics in this Meeting Summary Welcome and Introductions .......................................................................................................................... 1 Update on Timely Public Involvement Topics ............................................................................................. 1 Public Involvement for Technical

  18. DECONTAMINATION DRESSDOWN AT A TRANSPORTATION ACCIDENT INVOLVING...

    Office of Environmental Management (EM)

    Video User' s Guide DECONTAMINATION DRESSDOWN AT A TRANSPORTATION ACCIDENT INVOLVING ... related to emergency response to a transportation accident involving radioactive material. ...

  19. Community Involvement | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Involvement Community Involvement Y-12 is committed to keeping the community informed in areas of operations, environmental concerns, safety and emergency preparedness. To...

  20. Paducah WDA CERCLA Process & Public Involvement

    Broader source: Energy.gov [DOE]

    DOE is committed to fostering meaningful community involvement in environmental remediation decision making at the site.

  1. DOE - NNSA/NFO -- EM Public Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Public Involvement NNSA/NFO Language Options U.S. DOE/NNSA - Nevada Field Office Click to subscribe to NNSS News Public Involvement Public Involvement Outreach Photo An integral component of the Environmental Management Program is the public involvement function. Communication with the public is an essential element in successfully conducting Environmental Management work. Public involvement initiatives include developing and distributing fact sheets, publications, and exhibits as well as

  2. EMERGENCY RESPONSE TO A TRANSPORTATION ACCIDENT INVOLVING RADIOACTIVE...

    Office of Environmental Management (EM)

    ransportation ransportation ransportation ransportation Accident Involving Radioactive Material Accident Involving Radioactive Material Accident Involving Radioactive ...

  3. Public Involvement Plan | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Public Involvement Plan Public Involvement Plan Every three years, the Public Involvement Plan is updated, prepared, and published by the U.S. Department of Energy Oak Ridge Office of Environmental Management (DOE-OREM) to communicate to you, as a member of the public, the opportunities you have to participate in decisions and information exchanges regarding the remediation of contaminated areas on the Oak Ridge Site. DOE is committed to fostering meaningful public involvement in all aspects of

  4. Public Involvement and Communications Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    11, 2011 FINAL MEETING SUMMARY HANFORD ADVISORY BOARD PUBLIC INVOLVEMENT & COMMUNICATIONS COMMITTEE MEETING October 11, 2011 Richland, WA Topics in this Meeting Summary Welcome and Introductions ............................................................................................................ 1 Draft Advice - Draft Hanford Public Involvement Plan ................................................................ 1 Public Meetings - Draft Hanford Public Involvement Plan

  5. Nuclear criticality safety experiments, calculations, and analyses - 1958 to 1982. Volume 2. Summaries. Complilation of papers from the Transactions of the American Nuclear Society

    SciTech Connect (OSTI)

    Koponen, B.L.; Hampel, V.E.

    1982-10-21

    This compilation contains 688 complete summaries of papers on nuclear criticality safety as presented at meetings of the American Nuclear Society (ANS). The selected papers contain criticality parameters for fissile materials derived from experiments and calculations, as well as criticality safety analyses for fissile material processing, transport, and storage. The compilation was developed as a component of the Nuclear Criticality Information System (NCIS) now under development at the Lawrence Livermore National Laboratory. The compilation is presented in two volumes: Volume 1 contains a directory to the ANS Transaction volume and page number where each summary was originally published, the author concordance, and the subject concordance derived from the keyphrases in titles. Volume 2 contains-in chronological order-the full-text summaries, reproduced here by permission of the American Nuclear Society from their Transactions, volumes 1-41.

  6. Reducing Transaction Costs for Energy Efficiency Investments and Analysis of Economic Risk Associated With Building Performance Uncertainties: Small Buildings and Small Portfolios Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reducing Transaction Costs for Energy Efficiency Investments and Analysis of Economic Risk Associated With Building Performance Uncertainties Small Buildings and Small Portfolios Program Rois Langner, Bob Hendron, and Eric Bonnema Technical Report NREL/TP-5500-60976 August 2014 NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy Operated by the Alliance for Sustainable Energy, LLC This report is available at no cost from the National

  7. Public Involvement and Communications Committee Summaries - Hanford...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    05, 2012 Final Attachment 1: Tri-Party Agreement Agencies - Public Involvement Calendar Fiscal Year 2012 - not available Attachment 2: PIC Meeting Transcribed Flip Chart Notes...

  8. Community Involvement and Making a Difference

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2016 all issues All Issues submit Community Involvement and Making a Difference A personal message from Kurt Steinhaus, Community Programs Director, Los Alamos National...

  9. Public Involvement and Communications Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    November 2, 2011 FINAL MEETING SUMMARY HANFORD ADVISORY BOARD PUBLIC INVOLVEMENT & COMMUNICATIONS COMMITTEE MEETING November 2, 2011 Kennewick, WA Topics in this Meeting Summary...

  10. Central Plateau Principles Public Involvement Advice DETAILED...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    v0, 12914 Central Plateau Principles Public Involvement Advice DETAILED BACKGROUND Cleanup of Hanford's Central Plateau is expected to take another four decades or longer, and...

  11. Public Involvement and Communications Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    said he believes the heart of the Plan is in pages 7 to 11. He said the section uses language that is frequently used by the Board, including public involvement for better long...

  12. Public Involvement and Communications Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    January 13, 2011 FINAL MEETING SUMMARY HANFORD ADVISORY BOARD PUBLIC INVOLVEMENT & COMMUNICATIONS COMMITTEE MEETING January 13, 2011 Richland, WA Topics in this Meeting Summary Welcome and Introductions ............................................................................................................ 1 State of the Site Meetings ............................................................................................................... 2 Open Government Plan Advice

  13. Strategic Public Involvement Products For Review

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Public Involvement Products For Review PIC Discussion September 4, 2013 1 This list is from July 7, 2010 before we had decided on writing advice and is purely for reference for...

  14. Decontamination Dressdown at a Transportation Accident Involving

    Office of Environmental Management (EM)

    Radioactive Material | Department of Energy Decontamination Dressdown at a Transportation Accident Involving Radioactive Material Decontamination Dressdown at a Transportation Accident Involving Radioactive Material The purpose of this User's Guide is to provide instructors with an overview of the key points covered in the video. The Student Handout portion of this Guide is designed to assist the instructor in reviewing those points with students. The Student Handout should be distributed to

  15. A Good Neighbor: Community Involvement | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A Good Neighbor: Community Involvement At NREL, we are dedicated environmental stewards and are committed to making positive contributions in our community. NREL's main campus is a model for environmental protection and sustainable building practices. Photo of a volunteer at the Foothills Animal Shelter. Charitable Contributions Employees are very involved in the community, giving their time, money, and energy. As staff levels have grown, so have contributions, making NREL Jefferson County's

  16. FOIASI - Special Inquiry Review of Allegations Involving

    Energy Savers [EERE]

    PotentialMisconduct by a Senior Office of Environmental Management Official | Department of Energy FOIASI - Special Inquiry Review of Allegations Involving PotentialMisconduct by a Senior Office of Environmental Management Official FOIASI - Special Inquiry Review of Allegations Involving PotentialMisconduct by a Senior Office of Environmental Management Official In September 2009, the Office of Inspector General (OIG) received multiple allegations concerning improprieties by a senior

  17. Manager`s views of public involvement

    SciTech Connect (OSTI)

    Branch, K.M.; Heerwagen, J.; Bradbury, J.

    1995-12-01

    Four issues commonly form the framework for debates about the acceptability of proposed projects or technologies--the substantive decision or technological choice; the treatment of the community by the proponent organization; the way the decision-making process has been structured and managed; and the status of institutional safeguards and protection. One of the clear messages of cultural theory is that differences in perspectives are a normal and inevitable part of society, and that attempts to resolve differences by persuasion are not likely to work. These findings are useful when considering the goals and possibilities of public involvement as a decision-making tool, and when designing or evaluating public involvement training programs for managers. The research reported here examines the viewpoints and concerns of managers and decision-makers about the four issues identified above, with particular emphasis on their perspectives and concerns about opening decision-making processes to the public and about managers` roles and responsibilities for structuring and managing open decision-making processes. Implications of these findings for public involvement training for managers is also discussed. The data presented in this paper were obtained from face-to-face interviews with managers and decision-makers with experience managing a variety of hazardous waste management decision-making processes. We conducted these interviews in the course of four separate research projects: needs assessments to support the design and development of a public involvement training program for managers; a study of community residents` and managers` perspectives on the chemical stockpile disposal program; an evaluation of the effectiveness of public involvement training for managers in the Department of Energy; and a study to develop indicators of the benefits and costs of public involvement.

  18. Reducing Transaction Costs for Energy Efficiency Investments and Analysis of Economic Risk Associated With Building Performance Uncertainties: Small Buildings and Small Portfolios Program

    SciTech Connect (OSTI)

    Langner, R.; Hendron, B.; Bonnema, E.

    2014-08-01

    The small buildings and small portfolios (SBSP) sector face a number of barriers that inhibit SBSP owners from adopting energy efficiency solutions. This pilot project focused on overcoming two of the largest barriers to financing energy efficiency in small buildings: disproportionately high transaction costs and unknown or unacceptable risk. Solutions to these barriers can often be at odds, because inexpensive turnkey solutions are often not sufficiently tailored to the unique circumstances of each building, reducing confidence that the expected energy savings will be achieved. To address these barriers, NREL worked with two innovative, forward-thinking lead partners, Michigan Saves and Energi, to develop technical solutions that provide a quick and easy process to encourage energy efficiency investments while managing risk. The pilot project was broken into two stages: the first stage focused on reducing transaction costs, and the second stage focused on reducing performance risk. In the first stage, NREL worked with the non-profit organization, Michigan Saves, to analyze the effects of 8 energy efficiency measures (EEMs) on 81 different baseline small office building models in Holland, Michigan (climate zone 5A). The results of this analysis (totaling over 30,000 cases) are summarized in a simple spreadsheet tool that enables users to easily sort through the results and find appropriate small office EEM packages that meet a particular energy savings threshold and are likely to be cost-effective.

  19. IEEE TRANSACTIONS ON CYBERNETICS

    SciTech Connect (OSTI)

    Craig R. RIeger; David H. Scheidt; William D. Smart

    2014-11-01

    MODERN societies depend on complex and critical infrastructures for energy, transportation, sustenance, medical care, emergency response, communications security. As computers, automation, and information technology (IT) have advanced, these technologies have been exploited to enhance the efficiency of operating the processes that make up these infrastructures

  20. Transactional Network Overview

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... BACnet communications * On-demand defrost cycle implementation on supermarket refrigeration system * Lighting systems fault detection and diagnostics and controls * Host a workshop ...

  1. Public Involvement and Communications Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    June 1, 2011 FINAL MEETING SUMMARY HANFORD ADVISORY BOARD PUBLIC INVOLVEMENT & COMMUNICATIONS COMMITTEE MEETING June 1, 2011 Kennewick, WA Topics in this Meeting Summary Welcome and Introductions .......................................................................................................................... 1 Comprehensive Debrief - State of the Site Meetings ................................................................................... 4 Public Meetings - PW-1/3/6 and CW-5

  2. Sandia National Laboratories: Community Involvement: Volunteer Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Community Involvement Contribution Programs Volunteer Programs Education Programs About Volunteer Programs Helping where we are needed Habitat for Humanity Employees and retirees are passionate about volunteering. You'll find Sandians judging science fairs, coaching sports teams, leading scouting troops, sorting food, building houses, and serving on community boards. In support of individual volunteer efforts, Sandia provides a volunteer website to advertise current volunteer opportunities and

  3. Sandia National Laboratories: About Sandia: Community Involvement:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Programs: Science, Technology, Engineering and Math Programs Science, Technology, Engineering, and Math Programs Future scientists photo Our science, technology, engineering, and math (STEM) programs engage students by linking science to the real world. We offer three unique programs for American Indian students, African American students, and Hispanic students. The programs get students involved in fun, hands-on science and engineering activities and provide an opportunity to

  4. Radiative Decays Involving Light Scalar Mesons

    SciTech Connect (OSTI)

    Deirdre Black; Masayasu Harada; Joseph Schechter

    2002-09-01

    We present a vector dominance model to describe radiative decays involving the light scalar mesons. Assuming that the light scalar mesons form a nonet this model gives relations among various decay amplitudes of the form S--> gamma gamma, V-->Sgamma and S--> Vgamma, where S and V denote scalar and vector mesons. By comparing with experimental radiative decay rates, including those recently measured for phi--> PP'gamma, we obtain various predictions. We discuss briefly ongoing extensions of the present work in an attempt to describe the radiative phi decay measurements in detail.

  5. Apolipoprotein gene involved in lipid metabolism

    DOE Patents [OSTI]

    Rubin, Edward; Pennacchio, Len A.

    2007-07-03

    Methods and materials for studying the effects of a newly identified human gene, APOAV, and the corresponding mouse gene apoAV. The sequences of the genes are given, and transgenic animals which either contain the gene or have the endogenous gene knocked out are described. In addition, single nucleotide polymorphisms (SNPs) in the gene are described and characterized. It is demonstrated that certain SNPs are associated with diseases involving lipids and triglycerides and other metabolic diseases. These SNPs may be used alone or with SNPs from other genes to study individual risk factors. Methods for intervention in lipid diseases, including the screening of drugs to treat lipid-related or diabetic diseases are also disclosed.

  6. Genomic Aspects of Research Involving Polyploid Plants

    SciTech Connect (OSTI)

    Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

    2011-01-01

    Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

  7. 10.0 COMMUNITY RELATIONS/PUBLIC INVOLVEMENT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    0-1 10.0 COMMUNITY RELATIONSPUBLIC INVOLVEMENT 10.1 INTRODUCTION This section describes, in general, the way in which the public will be involved with the implementation of this...

  8. Workplace Charging Challenge Partner: JLA Public Involvement | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy JLA Public Involvement Workplace Charging Challenge Partner: JLA Public Involvement Workplace Charging Challenge Partner: JLA Public Involvement Joined the Challenge: March 2013 Headquarters: Portland, OR Charging Location: Portland, OR Domestic Employees: 15 Purchasing a plug-in electric vehicle (PEV) and installing a charging station has expanded JLA Public Involvement's sustainability efforts and allowed them to achieve Gold certification in the City of Portland's Sustainability

  9. Prototype indicators of value added through public involvement

    SciTech Connect (OSTI)

    Lach, D.; Hixson, P.; Ramonas, L.

    1995-12-01

    As more managers realize that public input in public sector decision making is a given in the current political and social climate, many are turning to public involvement as a way to manage input so that it is beneficial to their decisions and projects. Public involvement is starting to become a familiar way of doing business for many Federal agencies and its contractors. Yet, many, if not most agency and contractor managers are still unclear about the value and costs that public involvement adds to their projects. Proponents claim that public involvement increases the acceptability of project goals by increasing stakeholders` knowledge about and involvement in decisions of importance to them. In spite of these assertions avowing the benefits of public involvement, proponents have not generated methods that demonstrate or provide evidence of such value added through incorporating public involvement into projects. As these questions about the value and costs of public involvement efforts increase, there is a pressing need to document the value and costs of public involvement for the participants in these processes--the stakeholders--and to present this information to decision makers in ways that help them assess the value and costs of managing public input through a public involvement program.

  10. DOE Involvement in Consensus Negotiations for Energy Conservation Standards

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    | Department of Energy Involvement in Consensus Negotiations for Energy Conservation Standards DOE Involvement in Consensus Negotiations for Energy Conservation Standards DOE Involvement in Consensus Negotiations for Energy Conservation Standards. The Department of Energy is supportive of outside parties' negotiations efforts to reach consensus on energy conservation standards and test procedures that can be presented for consideration by the Department However, neither the Department nor

  11. Draft Public Involvement Advice for Central Plateau Cleanup

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    V0, 12914 Draft Public Involvement Advice for Central Plateau Cleanup Principles Issue managers: Pollet, Mattson, Vanni, Plahuta, Catrell Background The Tri-Party Agencies are...

  12. Tri-Party Agreement Hanford Public Involvement Plan

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    from the Comment and Response Document on the Tri-Party Agreement Hanford Public Involvement Plan The comments submitted by the Hanford Advisory Board (Advice 251) were...

  13. Tri-Party Agreement Agencies - Public involvement calendar -...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TRI-PARTY AGREEMENT AGENCIES - PUBLIC INVOLVEMENT CALENDAR - FISCAL YEAR 2015 - SEPTEMBER 2015 EVENTS IN PROGRESSCOMING SOON September 2015 October 2015 November 2015 Tri-Party...

  14. FOIASI - Special Inquiry Review of Allegations InvolvingPotentialMisc...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The allegations involved potential violations of political activity restrictions, lack of impartiality in performing official duties, misuse of position, and other related ...

  15. Multidomain Carbohydrate-binding Proteins Involved in Bacteroides

    Office of Scientific and Technical Information (OSTI)

    thetaiotaomicron Starch Metabolism (Journal Article) | SciTech Connect Multidomain Carbohydrate-binding Proteins Involved in Bacteroides thetaiotaomicron Starch Metabolism Citation Details In-Document Search Title: Multidomain Carbohydrate-binding Proteins Involved in Bacteroides thetaiotaomicron Starch Metabolism Authors: Cameron, Elizabeth A. ; Maynard, Mallory A. ; Smith, Christopher J. ; Smith, Thomas J. ; Koropatkin, Nicole M. ; Martens, Eric C. [1] ; Danforth) [2] + Show Author

  16. Fine-tuning Philippine transactions

    SciTech Connect (OSTI)

    Vitale, R.

    1994-11-01

    Expanding the power generation and distribution capability of the Philippines remains a top priority of the Philippine government. It is therefore not surprising that a number of the most significant legislative initiatives approved by the Philippine legislature in the past few years have been designed to encourage these activities in particular. There are several recent, significant statutes that will affect both power and non-power projects undertaken in the Philippines.

  17. Best Practices for Emergency Response to Incidents Involving...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -- Page iii -- FOREWORD Fires involving cars, trucks and other highway vehicles are a ... and PPE 194 8.2.1 General Procedures for Hybrid and EDV Fire Suppression 194 8.2.2 ...

  18. Getting Involved in Manufacturing Day – College Educators Edition Webinar

    Broader source: Energy.gov [DOE]

    This webinar will help address questions on why and how community colleges, universities, and technical schools can get involved with MFG DAY.  Led by MFG DAY Co-Producers, the webinar will also...

  19. Drum Involved in Idaho Incident Not Shippable to WIPP

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The drum involved in the venting incident was not shippable to WIPP as packaged. Sealed drums cannot be shipped to WIPP without venting. The drum in the incident had been sealed...

  20. Global prevalence and distribution of genes and microorganisms involved in

    Office of Scientific and Technical Information (OSTI)

    mercury methylation (Journal Article) | DOE PAGES Global prevalence and distribution of genes and microorganisms involved in mercury methylation « Prev Next » Title: Global prevalence and distribution of genes and microorganisms involved in mercury methylation Mercury methylation produces the neurotoxic, highly bioaccumulative methylmercury (MeHg). Recent identification of the methylation genes (hgcAB) provides the foundation for broadly evaluating microbial Hg-methylation potential in

  1. Integrated Analysis of Protein Complexes and Regulatory Networks Involved

    Office of Scientific and Technical Information (OSTI)

    in Anaerobic Energy Metabolism of Shewanella Oneidensis MR-1 (Technical Report) | SciTech Connect Technical Report: Integrated Analysis of Protein Complexes and Regulatory Networks Involved in Anaerobic Energy Metabolism of Shewanella Oneidensis MR-1 Citation Details In-Document Search Title: Integrated Analysis of Protein Complexes and Regulatory Networks Involved in Anaerobic Energy Metabolism of Shewanella Oneidensis MR-1 Anaerobic Nitrate Reduction. Nitrate is an extensive co-contaminant

  2. Memory and Spin Injection Devices Involving Half Metals (Journal Article) |

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Memory and Spin Injection Devices Involving Half Metals Citation Details In-Document Search Title: Memory and Spin Injection Devices Involving Half Metals Authors: Shaughnessy, M. ; Snow, Ryan ; Damewood, L. ; Fong, C. Y. Publication Date: 2011-01-01 OSTI Identifier: 1198038 Grant/Contract Number: AC52-07NA27344 Type: Published Article Journal Name: Journal of Nanomaterials Additional Journal Information: Journal Volume: 2011; Journal ID: ISSN 1687-4110 Publisher: Hindawi

  3. NEPA-Related Public Involvement | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NEPA-Related Public Involvement NEPA-Related Public Involvement The Loan Programs Office's NEPA-related hearings, public meetings, and public notices (e.g. public scoping meeting, public hearing, notice of proposed floodplain or wetland action) are presented below under NEPA-Related Hearings, Meetings, and Notices. Available environmental documents can be found at the following links: Categorical Exclusions Environmental Assessments Environmental Impact Statements NEPA-Related Hearings,

  4. Accurate Numerical Simulations Of Chemical Phenomena Involved in Energy

    Office of Scientific and Technical Information (OSTI)

    Production and Storage with MADNESS and MPQC: ALCF-2 Early Science Program Technical Report (Technical Report) | SciTech Connect Technical Report: Accurate Numerical Simulations Of Chemical Phenomena Involved in Energy Production and Storage with MADNESS and MPQC: ALCF-2 Early Science Program Technical Report Citation Details In-Document Search Title: Accurate Numerical Simulations Of Chemical Phenomena Involved in Energy Production and Storage with MADNESS and MPQC: ALCF-2 Early Science

  5. Get Involved with Home Energy Score | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Home Energy Score » Get Involved with Home Energy Score Get Involved with Home Energy Score The Department of Energy's (DOE) Home Energy Score helps homeowners understand the energy performance of their homes and how they compare to other homes nationwide. Energy professionals and organizations can use the Score to promote energy efficiency to homeowners and encourage investments in energy improvements. Information for Homeowners Information for Interested Organizations Information for

  6. Metaproteomics Identifies the Protein Machinery Involved in Metal and

    Office of Scientific and Technical Information (OSTI)

    Radionuclide Reduction in Subsurface Microbiomes and Elucidates Mechanisms and U(VI) Reduction Immobilization (Technical Report) | SciTech Connect Technical Report: Metaproteomics Identifies the Protein Machinery Involved in Metal and Radionuclide Reduction in Subsurface Microbiomes and Elucidates Mechanisms and U(VI) Reduction Immobilization Citation Details In-Document Search Title: Metaproteomics Identifies the Protein Machinery Involved in Metal and Radionuclide Reduction in Subsurface

  7. Consistent analysis of one-nucleon spectroscopic factors involving weakly-

    Office of Scientific and Technical Information (OSTI)

    and strongly-bound nucleons (Journal Article) | SciTech Connect Consistent analysis of one-nucleon spectroscopic factors involving weakly- and strongly-bound nucleons Citation Details In-Document Search Title: Consistent analysis of one-nucleon spectroscopic factors involving weakly- and strongly-bound nucleons Authors: Okołowicz, J. ; Lam, Y. H. ; Płoszajczak, M. ; Macchiavelli, A. O. ; Smirnova, N. A. Publication Date: 2016-04-01 OSTI Identifier: 1246192 Grant/Contract Number:

  8. Emergency Response to a Transportation Accident Involving Radioactive

    Office of Environmental Management (EM)

    Material | Department of Energy Response to a Transportation Accident Involving Radioactive Material Emergency Response to a Transportation Accident Involving Radioactive Material The purpose of this User's Guide is to provide instructors with an overview of the key points covered in the video. The Student Handout portion of this Guide is designed to assist the instructor in reviewing those points with students. The Student Handout should be distributed to students after the video is shown

  9. Draft Public Involvement Advice for Central Plateau Cleanup

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    V0, 12/9/14 Draft Public Involvement Advice for Central Plateau Cleanup Principles Issue managers: Pollet, Mattson, Vanni, Plahuta, Catrell Background The Tri-Party Agencies are developing principles that will guide the cleanup of Hanford's Central Plateau. The Hanford Advisory Board (HAB) believes that the broader public should be involved in the development of these principles. Hanford's Central Plateau is planned to be the final footprint of the Hanford Site. The Central Plateau contains

  10. Community assessments: Road maps to successful public involvement

    SciTech Connect (OSTI)

    Forrest, C.J.

    1995-12-01

    This paper presents a framework for performing comprehensive community assessments to increase the effectiveness of public involvement efforts. The community assessment process involves systematic and critical examination of beliefs, attitudes, opinions and knowledge of the many groups in the community. A good community assessment gathers information on the concerns or issues directly related to an environmental project as well as other important community issues to ensure development of an effective public involvement program. The framework discusses types of people and organizations that should be included in the community assessment interview process. It also delineates steps that persons charged with performing assessments can take to ensure that the views of all potential stakeholders are included--a necessary consideration in communities that are ethnically, racially, or economically diverse. Lastly, the framework discusses types of written materials that can be analyzed for additional insight into communities. For example, it discusses methods for reviewing past issues of the local newspaper to provide both validation of the information gathered during interviews and an understanding of the ways that community members give and receive information and respond to conflict or perceived threats. This framework is designed to show environmental professionals who are responsible for public involvement how to perform an initial community assessment. It provides illustrations of instances in which information vital to a successful public involvement effort has been uncovered through a careful assessment of the community. Both the U.S. EPA and the public have made clear their intentions to require increased public involvement. Many of these efforts will succeed or fail based on how well those charged with the public involvement component of environmental projects identify community issues and design communications programs that successfully reach all stakeholders.

  11. Tri-Party Agreement Agencies Annual Hanford Public Involvement Survey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    7 Tri-Party Agreement Agencies Annual Hanford Public Involvement Survey 1. How do you usually receive information about Hanford topics? (Please select all that apply) Response Percent Response Count Advisory Board 23.7% 22 Citizens Group 32.3% 30 Ecology website 21.5% 20 Hanford.gov website 33.3% 31 Hanford Listserv (email) 54.8% 51 Hanford Mailing (postal) 12.9% 12 Newspaper 48.4% 45 Radio 26.9% 25 Social Media (Facebook, Twitter, etc.) 26.9% 25 Television 17.2% 16 Work Announcements 11.8% 11 I

  12. Probative Investigation of the Thermal Stability of Wastes Involved in

    Energy Savers [EERE]

    ProActive DNS Blacklisting ProActive DNS Blacklisting PDF icon Tuesday_Fair_Park_2_1330_Rackow.pdf More Documents & Publications DNS as a Covert Channel Within Protected Networks Cyber Security Procurement Language for Control Systems Version 1.8 Slide February 2014 Waste Isolation Pilot Plant (WIPP) Waste Drum Breach Event | Department of Energy

    Probative Investigation of the Thermal Stability of Wastes Involved in February 2014 Waste Isolation Pilot Plant (WIPP) Waste Drum Breach

  13. Central Plateau Principles Public Involvement Advice DETAILED BACKGROUND

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    v0, 12/9/14 Central Plateau Principles Public Involvement Advice DETAILED BACKGROUND Cleanup of Hanford's Central Plateau is expected to take another four decades or longer, and cost tens of billions of dollars. The Central Plateau includes the 200 East and 200 West Areas with all of Hanford's High-Level Nuclear Waste Tank Farms, processing plants, sites where over a million gallons of High-Level Nuclear Waste has leaked from Single Shell Tanks (SSTs), and billions of gallons of waste was

  14. Antitrust aspects of involvement by utilities in residential solar energy

    SciTech Connect (OSTI)

    Hurst, T.R.

    1983-01-01

    A utility that merely engages in the sale of solar units produced by independent manufacturers on a nonexclusive basis appears to run little risk of violating federal antitrust laws, but virtually every other unregulated activity would involve enough significant exposure to antitrust liability to preclude a prudent utility from engaging in them on any basis other than one where the state-action exemption clearly shields the utility. The case cited in this review indicates that municipal utilities must be equally cautious when engaging in pro-solar activities that may have an anticompetitive impact on various parties who could become plaintiffs in a private antitrust action. 47 references.

  15. Market power and foreign involvement by US multinationals

    SciTech Connect (OSTI)

    Hirschey, M.

    1982-05-01

    This study considers the relationship between market power and multinational involvement through use of a market-valuation approach. Estimation results for a sample of large US multinationals reveal superior valuation effects due to returns from foreign as opposed to domestic operations. This finding is consistent with the hypothesis that returns from the US market tend to be less secure, and therefore less valued, than are returns from foreign markets due to both real (market size, entry barriers, etc.) and institutional (antitrust policies, etc.) differences in competitive environments. Such findings are also consistent with previous suggestions that firms develop markets abroad in order to exploit economic-rent opportunities. These findings remain tentative, however, and await verification in future studies of data from both the United States and abroad. 13 references, 1 table.

  16. Representation of analysis results involving aleatory and epistemic uncertainty.

    SciTech Connect (OSTI)

    Johnson, Jay Dean; Helton, Jon Craig; Oberkampf, William Louis; Sallaberry, Cedric J.

    2008-08-01

    Procedures are described for the representation of results in analyses that involve both aleatory uncertainty and epistemic uncertainty, with aleatory uncertainty deriving from an inherent randomness in the behavior of the system under study and epistemic uncertainty deriving from a lack of knowledge about the appropriate values to use for quantities that are assumed to have fixed but poorly known values in the context of a specific study. Aleatory uncertainty is usually represented with probability and leads to cumulative distribution functions (CDFs) or complementary cumulative distribution functions (CCDFs) for analysis results of interest. Several mathematical structures are available for the representation of epistemic uncertainty, including interval analysis, possibility theory, evidence theory and probability theory. In the presence of epistemic uncertainty, there is not a single CDF or CCDF for a given analysis result. Rather, there is a family of CDFs and a corresponding family of CCDFs that derive from epistemic uncertainty and have an uncertainty structure that derives from the particular uncertainty structure (i.e., interval analysis, possibility theory, evidence theory, probability theory) used to represent epistemic uncertainty. Graphical formats for the representation of epistemic uncertainty in families of CDFs and CCDFs are investigated and presented for the indicated characterizations of epistemic uncertainty.

  17. Personnel involved in nuclear standards development: 1980 directory

    SciTech Connect (OSTI)

    Carr, S.J.

    1980-03-01

    The development of nuclear standards is an active and necessary endeavor that is concerned with the safe, orderly, and economic development of nuclear potential. There are almost 4100 people from the teachnical community who are presently involved either in writing nuclear standards, including codes, or in the management and processing roles necessary for their approval and promulgation. This document identifies the current participation of each individual as member, chairman, cochairman (vice-chairman), or secretary of about 700 standards development committees and groups. The standards committees and groups are identified with the organizations that are responsible for the preparation, review, and maintenance of the standards and that provide support through supervisory committees and headquarters staff. This directory includes four major sections: personnel, employers, committees, and a Key-Word-in-Context (KWIC) Index of committee titles. It can also be used to identify the participation of employers as well as to recognize the contributions of individuals to the often interdisciplinary activity of standards development.

  18. Surface interactions involved in flashover with high density electronegative gases.

    SciTech Connect (OSTI)

    Hodge, Keith Conquest; Warne, Larry Kevin; Jorgenson, Roy Eberhardt; Wallace, Zachariah Red; Lehr, Jane Marie

    2010-01-01

    This report examines the interactions involved with flashover along a surface in high density electronegative gases. The focus is on fast ionization processes rather than the later time ionic drift or thermalization of the discharge. A kinetic simulation of the gas and surface is used to examine electron multiplication and includes gas collision, excitation and ionization, and attachment processes, gas photoionization and surface photoemission processes, as well as surface attachment. These rates are then used in a 1.5D fluid ionization wave (streamer) model to study streamer propagation with and without the surface in air and in SF6. The 1.5D model therefore includes rates for all these processes. To get a better estimate for the behavior of the radius we have studied radial expansion of the streamer in air and in SF6. The focus of the modeling is on voltage and field level changes (with and without a surface) rather than secondary effects, such as, velocities or changes in discharge path. An experiment has been set up to carry out measurements of threshold voltages, streamer velocities, and other discharge characteristics. This setup includes both electrical and photographic diagnostics (streak and framing cameras). We have observed little change in critical field levels (where avalanche multiplication sets in) in the gas alone versus with the surface. Comparisons between model calculations and experimental measurements are in agreement with this. We have examined streamer sustaining fields (field which maintains ionization wave propagation) in the gas and on the surface. Agreement of the gas levels with available literature is good and agreement between experiment and calculation is good also. Model calculations do not indicate much difference between the gas alone versus the surface levels. Experiments have identified differences in velocity between streamers on the surface and in the gas alone (the surface values being larger).

  19. Classroom simulation of public involvement in H.L.W. issues featuring STS concepts

    SciTech Connect (OSTI)

    Bieniawski, Z.T.

    1996-12-01

    This paper reports on a classroom experiment, now in its third year, conducted by the author for students involvement in High-Level Waste disposal. The project involved designing a methodology for HLW management in the United States.

  20. R-Axion: A New LHC Physics Signature Involving Muon Pairs (Conference...

    Office of Scientific and Technical Information (OSTI)

    Conference: R-Axion: A New LHC Physics Signature Involving Muon Pairs Citation Details In-Document Search Title: R-Axion: A New LHC Physics Signature Involving Muon Pairs In a class ...

  1. Getting Involved

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    received help navigating the draft EIS and asked questions about the project, the EIS process, documentation and how to submit comments on the document. There were no formal...

  2. Customer Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Projects Expand Projects Skip navigation links Ancillary and Control Area Services (ACS) Practices Forum Meetings Customer Comments Attachment K 2015 Planning Cycle 2014...

  3. Involvement & Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Volunteers - Sign Up About Science Bowl Curriculum and Activities How to Build a Motor The Great Marble Drop How to Build a Turbine How to Build a Tower Classroom...

  4. Sensors, Controls, & Transactional Network Reports | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Network Reports Buildings-to-Grid Technical Opportunities: Introduction and Vision (Mar 2014) Buildings-to-Grid Technical Opportunities: From the Buildings Perspective (Mar...

  5. Electricity transactions across international borders, 1984

    SciTech Connect (OSTI)

    Not Available

    1985-10-01

    This report summarizes the electricity exchanges between the United States and Mexico and Canada during calendar year 1984. The construction, operation and maintenance of any electric transmission facility which crosses an international border of the United States requires a Presidential permit. These permits have been granted by DOE since its formation in 1977. During 1984, the US imported 42,219,259 MWh of electric energy at a cost of $1,070,046,345. Of this total, 42,034,392 MWh were imported from Canada and the remainder (184,867 MWh) were received from Mexico. During this same period, US exports of electric energy totaled 2,558,293 MWh with gross revenues of $21,795,733. Of this, 2,479,487 MWh representing $21,115,413 in revenues were delivered to Canada, and 78,806 MWh representing $680,320 in revenues were delivered to Mexico. On a net basis, the US was an importer of 39,660,966 MWh of electric energy. These 1984 values constitute an increase of 9.2% in gross imports and a decrease of 23.3% in gross exports compared to 1983 levels.

  6. IEEE TRANSACTIONS ON PLASMA SCIENCE, VOL.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the average electronic thermal diffusivity in the region of the plasma where the pulse prop- agates. A model of diffusive heat propagation in a cylinder is under development and...

  7. DB-6 Precedent Transactions.xlsx

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Aug-11 Wind Energy Transmission Texas CREZ Rate Recovery Debt Mitsubishi UFJ, Deutsche Bank 500,000,000 Nov-11 Lone Star CREZ Rate Recovery Debt Mitsubishi UFJ, Mizuho, Credit ...

  8. SF 6432-IN International Commercial Transactions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    OR KICKBACKS INFORMATION OF SANDIA INFORMATION OF SELLER INSPECTION AND ACCEPTANCE LANGUAGE ORDER OF PRECEDENCE PAYMENT QUALITY CONTROL SYSTEM RIGHTS AND INTERESTS RISK OF LOSS...

  9. SF 6432-IN International Commercial Transactions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    RELATIONSHIP INFORMATION OF SELLER INFORMATION SECURITY INSPECTION AND ACCEPTANCE LANGUAGE ORDER OF PRECEDENCE PAYMENT QUALITY CONTROL SYSTEM RIGHTS AND INTERESTS RISK OF LOSS...

  10. Sensors, Controls, and Transactive Energy Research | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... This last category will lead to the greatest and most persistent increases in energy efficiency.. CONTACTS DOE Technology Manager: Marina Sofos Lead Performer: Andrew Nicholls, ...

  11. Sensors, Controls, & Transactional Network Projects | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lead Performer: Lawrence Berkeley National Lab -- U.S. India Joint Center for Building ... Hyderabad (IIIT-H) - Andhra Pradesh, India -- enLighted - Sunnyvale, California and ...

  12. Sensors, Controls, and Transactional Network | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    systems and devices that can automatically communicate their status, availability and identity would be optimal to facilitate better energy management at the grid, utility, and...

  13. Technical Meeting: Software Framework for Transactive Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Overview and Features (Carpenter) PDF icon Presentation: VOLTTRON Applications - LBNL (Brown) PDF icon Presentation: VOLTTRON Applications - ORNL (Kuruganti) PDF icon Presentation: ...

  14. 01-12-1998 - Bench Top FIre Involving Use of Alcohol and Burner...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1998 - Bench Top FIre Involving Use of Alcohol and Burner Document Number: NA Effective Date: 011998 File (public): PDF icon 01-12-1998...

  15. Public involvement in the regulatory activities regarding nuclear fuel cycle facilities: A case study

    SciTech Connect (OSTI)

    Austin, D.E.

    1995-12-01

    This paper reviews the involvement of a community-based organization in the activities of the Nuclear Regulatory Commission (NRC) regarding a uranium conversion facility that operated near Gore, Oklahoma from 1970 until 1992. Effective participation requires access to decision making. Access is a complex phenomenon that includes: (1) opportunity, both procedural and physical, (2) a common language, and (3) time and resources. The paper describes how both the community organization and the NRC responded to these requirements for access, the strategies that were most effective in securing meaningful public involvement in the decision making, and the impacts of that involvement on the organization.

  16. LANL gets young women involved in math and science at 31st Expanding...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LANL gets young women involved in math and science at 31st Expanding Your Horizons ... the Expanding Your Horizons in Math and Science(tm) Conference to give middle- ...

  17. Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis

    SciTech Connect (OSTI)

    Neff, Michael M.

    2011-06-23

    This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled “Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis”. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

  18. 01-12-1998 - Bench Top FIre Involving Use of Alcohol and Burner | The Ames

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory 1998 - Bench Top FIre Involving Use of Alcohol and Burner Document Number: NA Effective Date: 01/1998 File (public): PDF icon 01-12-1998

  19. Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase

    Office of Scientific and Technical Information (OSTI)

    Domain in Allosteric Regulation of Membrane Association of Proline Utilization A (Journal Article) | SciTech Connect Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A Citation Details In-Document Search Title: Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A Authors: Zhu, Weidong ; Haile,

  20. Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle

    Office of Scientific and Technical Information (OSTI)

    Formation in Pseudomonas aeruginosa PAO1 (Journal Article) | SciTech Connect SciTech Connect Search Results Journal Article: Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation in Pseudomonas aeruginosa PAO1 Citation Details In-Document Search Title: Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation in Pseudomonas aeruginosa PAO1 Authors: Li, Zhi ; Chen, Jui-Hui ; Hao, Yue ; Nair, Satish K. [1] + Show Author Affiliations UIUC

  1. Discovery of a new ATP-binding motif involved in peptidic azoline

    Office of Scientific and Technical Information (OSTI)

    biosynthesis (Journal Article) | SciTech Connect Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis Citation Details In-Document Search Title: Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis Authors: Dunbar, Kyle L. ; Chekan, Jonathan R. ; Cox, Courtney L. ; Burkhart, Brandon J. ; Nair, Satish K. ; Mitchell , Douglas A. [1] + Show Author Affiliations (UIUC) Publication Date: 2014-11-20 OSTI Identifier: 1163365 Resource Type: Journal

  2. Public Understanding of Cleanup Levels DRAFT FAQ Public Involvement Committee Meeting, Hanford Advisory Board

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DRAFT FAQ Public Involvement Committee Meeting, Hanford Advisory Board Wednesday, June 5, 2013 at the Red Lion Hanford House in Richland Cleanup Levels The better the public understands how cleanup levels are set to determine what the acceptable levels of residual contamination may be left at Hanford, the more effective and meaningful their input into cleanup decisions will be. We must stay informed in order to stay involved and provide meaningful input. Here are some frequently asked questions

  3. Public Understanding of Cleanup Levels Discussion Public Involvement Committee Meeting - Hanford Advisory Board

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Discussion Public Involvement Committee Meeting - Hanford Advisory Board Wednesday, October 31, 2012 - Red Lion Hanford House, Richland Page 1 of 4 Cleanup Levels One of the reasons we want public involvement on cleanup decisions is to gather input about what kind of cleanup end-state the public wants, how clean is clean, or put another way, how dirty is acceptable. Cleanup decisions are complicated. Cleanup levels necessary to be protective dictate which cleanup actions are viable to consider.

  4. SO2907, A Putative TonB-dependent Receptor, Is Involved in Dissimilatory

    Office of Scientific and Technical Information (OSTI)

    Iron Reduction by Shewanella oneidensis Strain MR-1 (Journal Article) | SciTech Connect Journal Article: SO2907, A Putative TonB-dependent Receptor, Is Involved in Dissimilatory Iron Reduction by Shewanella oneidensis Strain MR-1 Citation Details In-Document Search Title: SO2907, A Putative TonB-dependent Receptor, Is Involved in Dissimilatory Iron Reduction by Shewanella oneidensis Strain MR-1 Shewanella oneidensis strain MR-1 utilizes soluble and insoluble ferric ions as terminal electron

  5. Proposed Tenaska Washington II Generation Project : Final Environmental Impact Statement. Volume 2: Public Involvement.

    SciTech Connect (OSTI)

    United States. Bonneville Power Administration.

    1994-01-01

    In regard to the proposed Tenaska Washington II Generation Project, the goal of the Bonneville Power Administration`s (BPA) Environmental Impact Statement (EIS) public involvement process is to determine the issues to be examined and pertinent analyses to be conducted and to solicit comments on the content and quality of information presented in the Draft Environmental Impact Statement (DEIS). Comments and questions are solicited from the public and government agencies during the scoping process and during the comment period and public hearing on the DEIS, to find out what is of most concern to them. The end product of the public involvement process is the Comment Report which follows in part of this volume on Public Involvement.

  6. Getting the lead out: Citizen involvement in the Williamsburg Bridge lead paint removal project

    SciTech Connect (OSTI)

    Forker, T.R.

    1997-08-01

    This paper examines the process and results of citizen involvement in developing new environmental control and compliance procedures used by the New York City Department of Transportation (NYC DOT) for lead paint removal on the Williamsburg Bridge and other structures. As a case study of the effects of public involvement in environmental decision-making, the study identifies and discusses the factors that produced failures or successes in satisfying the citizen`s concerns about health risks and the effectiveness of the selected pollution control technology.

  7. Code Tables | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    Code Tables U.S. Department of Energy / U.S. Nuclear Regulatory Commission Nuclear Materials Management & Safeguards System Code Tables Action Code The action code identifies the type of activity being reported in a transaction. The Action Code table shows the valid action codes. Nature of Transaction (TI) Code The financial code signifies the nature of the financial or contractual activity that is involved in the transaction. The Nature of Transaction (TI) Code table shows the valid action

  8. Differing Professional Opinions Manual for Technical Issues Involving Environment, Safety, and Health

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2006-11-16

    This Manual establishes a differing professional opinion (DPO) policy to a Department of Energy (DOE) Differing Professional Opinion (DPO) Process to encourage and facilitate dialogue and resolution on DPOs from employees for technical issues involving environment, safety, and health. Does not cancel other directives. Canceled by DOE O 442.2.

  9. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  10. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county`s future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  11. The value of adding regional to local stakeholder involvement in evaluating the acceptability of innovative technologies

    SciTech Connect (OSTI)

    Peterson, T.; McCabe, G.; Niesen, K.; Patricia, S.

    1995-12-01

    Technology is urgently needed to clean up contamination by volatile organic compounds at United States Department of Energy (DOE) and industrial sites throughout the country. In many cases, however, existing technology is too slow, inefficient, or expensive. The record of technology development is similarly disappointing. Remediation technologies developed at great expense and evaluated piecemeal over long periods have not been deployed because, in the end, the public judged them ineffective or unacceptable. The need for remediation is too great and resources too limited to continue with ineffective technology evaluation. Early and continuing stakeholder involvement is essential to developing successful, deployable technologies. In order to make good decisions about which technologies to deploy, remedial project managers need to know stakeholders` requirements for the performance of proposed technologies. Expanding stakeholder involvement regionally identifies the concerns of a broad range of stakeholders at a arid DOE sites throughout the West - issues that must be taken into account if technologies are to be accepted for wide deployment.

  12. A statistical description of the types and severities of accidents involving tractor semi-trailers

    SciTech Connect (OSTI)

    Clauss, D.B.; Wilson, R.K.; Blower, D.F.; Campbell, K.L.

    1994-06-01

    This report provides a statistical description of the types and severities of tractor semi-trailer accidents involving at least one fatality. The data were developed for use in risk assessments of hazardous materials transportation. Several accident databases were reviewed to determine their suitability to the task. The TIFA (Trucks Involved in Fatal Accidents) database created at the University of Michigan Transportation Research Institute was extensively utilized. Supplementary data on collision and fire severity, which was not available in the TIFA database, were obtained by reviewing police reports for selected TIFA accidents. The results are described in terms of frequencies of different accident types and cumulative distribution functions for the peak contact velocity, rollover skid distance, fire temperature, fire size, fire separation, and fire duration.

  13. The people problems of NEPA: Social impact assessment and the role of public involvement

    SciTech Connect (OSTI)

    Carnes, S.A.

    1989-12-31

    This Chapter of the book `` The Scientific Challenges of NEPA`` discusses the people problems of NEPA and social impact assessment and the role of public involvement in NEPA. When Congress passed the National Environmental Policy Act (NEPA) in 1969, there was little guidance on the preparation of environmental impact statements (EIS) and the role of the public in the NEPA process. Excepting the statutory language of NEPA, which referred to impacts on the human environment, nowhere was this more evident than with respect to people. Questions such as what impacts on people should be assessed, how impacts on people should be assessed, and how people, including but not limited to those persons potentially impacted, should be involved in the assessment itself as well as NEPA`s associated administrative processes, were simply not addressed.

  14. The Department of Energy (DOE) is actively involved in leading the

    Energy Savers [EERE]

    (DOE) is actively involved in leading the development of advanced applications and tools to more effectively operate the electricity delivery system by enabling advanced analysis, visualization, monitoring and alarming, and decision support capabilities for grid operators. These applications use-and greatly increase the value of-data coming from high-resolution electrical measuring devices known as phasor measurement units (PMUs), whose deployment is being facilitated by the North American

  15. Temperature of aircraft cargo flame exposure during accidents involving fuel spills

    SciTech Connect (OSTI)

    Mansfield, J.A.

    1993-01-01

    This report describes an evaluation of flame exposure temperatures of weapons contained in alert (parked) bombers due to accidents that involve aircraft fuel fires. The evaluation includes two types of accident, collisions into an alert aircraft by an aircraft that is on landing or take-off, and engine start accidents. Both the B-1B and B-52 alert aircraft are included in the evaluation.

  16. Creating an Ethical Framework for Studies That Involve the Worker Community

    Office of Science (SC) Website

    | U.S. DOE Office of Science (SC) DOE Resources » Creating an Ethical Framework for Studies That Involve the Worker Community Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources CITI Courses DOE Resources Ethical Framework Informed Consent Special Research Categories Community IRB Member Resources Other Resources Human Subjects Research Database (HSRD) IRB7 Regulations and Requirements Glossary Abbreviations Contact BER Home

  17. Quality control procedures for dynamic treatment delivery techniques involving couch motion

    SciTech Connect (OSTI)

    Yu, Victoria Y.; Fahimian, Benjamin P.; Xing, Lei; Hristov, Dimitre H.

    2014-08-15

    In this study, the authors introduce and demonstrate quality control procedures for evaluating the geometric and dosimetric fidelity of dynamic treatment delivery techniques involving treatment couch motion synchronous with gantry and multileaf collimator (MLC). Tests were designed to evaluate positional accuracy, velocity constancy and accuracy for dynamic couch motion under a realistic weight load. A test evaluating the geometric accuracy of the system in delivering treatments over complex dynamic trajectories was also devised. Custom XML scripts that control the Varian TrueBeam STx (Serial #3) axes in Developer Mode were written to implement the delivery sequences for the tests. Delivered dose patterns were captured with radiographic film or the electronic portal imaging device. The couch translational accuracy in dynamic treatment mode was 0.01 cm. Rotational accuracy was within 0.3, with 0.04 cm displacement of the rotational axis. Dose intensity profiles capturing the velocity constancy and accuracy for translations and rotation exhibited standard deviation and maximum deviations below 3%. For complex delivery involving MLC and couch motions, the overall translational accuracy for reproducing programmed patterns was within 0.06 cm. The authors conclude that in Developer Mode, TrueBeam is capable of delivering dynamic treatment delivery techniques involving couch motion with good geometric and dosimetric fidelity.

  18. ABSTRACT: The Community Environmental Monitoring Program: Reducing Public Perception of Risk Through Stakeholder Involvement

    SciTech Connect (OSTI)

    T. Hartwell

    2007-02-28

    Between 1951 and 1992, 928 nuclear tests were conducted at the Nevada Test Site (NTS), including 100 atmospheric and 828 underground tests. Initial public reaction to the tests was largely supportive, but by the late 1950s this began to change, largely as a result of fear of the potential for adverse health effects to be caused by exposure to ionizing radiation resulting from the tests. The nuclear power plant accident at Three Mile Island in 1979 served to heighten these fears, as well as foster a general distrust of the federal agencies involved and low public confidence in monitoring results. Modeled after a similar program that involved the public in monitoring activities around the Three Mile Island nuclear power plant, the Community Environmental Monitoring Program (CEMP) has promoted stakeholder involvement, awareness, and understanding of radiological surveillance in communities surrounding the NTS since 1981. It involves stakeholders in the operation, data collection, and dissemination of information obtained from a network of 29 stations across a wide area of Nevada, Utah, and California. It is sponsored by the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) and administered by the Desert Research Institute (DRI) of the Nevada System of Higher Education. Since assuming administration of the program in 2000, DRI has accomplished significant enhancements to the network's data collection and transmission capabilities. A robust datalogging and communications system allows for the near real-time transmission of data to a platform maintained by DRI's Western Regional Climate Center, where the data are uploaded and displayed on a publicly accessible web site (http://cemp.dri.edu/). Additionally, the CEMP can serve as part of an emergency response network in the event of an unplanned radiological release from the NTS, and also provides an excellent platform for testing new environmental sensor technologies. Finally, the CEMP provides training workshops for involved stakeholders, and educational programs, which help to alleviate public perception of risk of health effects from past activities conducted at the NTS.

  19. Secretarial Policy Statement on Technology Transfer at Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Globalization and U.S. competitiveness are additional factors that also must be considered. 3. It is the policy of DOE that commercialization transactions involve partners with ...

  20. Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report

    SciTech Connect (OSTI)

    Baulch, Janet

    2013-09-11

    This is a 'glue grant' that was part of a DOE Low Dose project entitled 'Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation'. This collaborative program has involved Drs. David L. Springer from Pacific Northwest National Laboratory (PNNL), John H. Miller from Washington State University, Tri-cities (WSU) and William F. Morgan then from the University of Maryland, Baltimore (UMB). In July 2008, Dr. Morgan moved to PNNL and Dr. Janet E. Baulch became PI for this project at University of Maryland. In November of 2008, a one year extension with no new funds was requested to complete the proteomic analyses. The project stemmed from studies in the Morgan laboratory demonstrating that genomically unstable cells secret a soluble factor or factors into the culture medium, that cause cytogenetic aberrations and apoptosis in normal parental GM10115 cells. The purpose of this project was to identify the death inducing effect (DIE) factor or factors, estimate their relative abundance, identify the cell signaling pathways involved and finally recapitulate DIE in normal cells by exogenous manipulation of putative DIE factors in culture medium. As reported in detail in the previous progress report, analysis of culture medium from the parental cell line, and stable and unstable clones demonstrated inconsistent proteomic profiles as relate to candidate DIE factors. While the proposed proteomic analyses did not provide information that would allow DIE factors to be identified, the analyses provided another important set of observations. Proteomic analysis suggested that proteins associated with the cellular response to oxidative stress and mitochondrial function were elevated in the medium from unstable clones in a manner consistent with mitochondrial dysfunction. These findings correlate with previous studies of these clones that demonstrated functional differences between the mitochondria of stable and unstable clones. These mitochondrial abnormalities in the unstable clones contributes to oxidative stress.

  1. Electric-field enhanced performance in catalysis and solid-state devices involving gases

    DOE Patents [OSTI]

    Blackburn, Bryan M.; Wachsman, Eric D.; Van Assche, IV, Frederick Martin

    2015-05-19

    Electrode configurations for electric-field enhanced performance in catalysis and solid-state devices involving gases are provided. According to an embodiment, electric-field electrodes can be incorporated in devices such as gas sensors and fuel cells to shape an electric field provided with respect to sensing electrodes for the gas sensors and surfaces of the fuel cells. The shaped electric fields can alter surface dynamics, system thermodynamics, reaction kinetics, and adsorption/desorption processes. In one embodiment, ring-shaped electric-field electrodes can be provided around sensing electrodes of a planar gas sensor.

  2. On reaction mechanisms involved in the deuteron–induced surrogate reactions

    SciTech Connect (OSTI)

    Avrigeanu, M.; Avrigeanu, V.; Mănăilescu, C.

    2015-02-24

    An extended analysis of the nuclear reaction mechanisms involved within deuteron interaction with nuclei, namely the breakup, stripping, pick-up, pre-equilibrium emission, and evaporation from fully equilibrated compound nucleus, is presented in order to highlight the importance of the direct mechanisms still neglected in the analysis of deuteron-induced surrogate reactions. Particularly, the dominance of the breakup mechanism at low energies around the Coulomb barrier should be considered in the case of (d,x) surrogate reactions on actinide target nuclei.

  3. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    Not Available

    1999-01-01

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  4. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    1999-11-01

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  5. EIS-0467: Notice of Intent to Prepare an Environmental Impact Statement and Notice of Floodplains and Wetlands Involvement

    Broader source: Energy.gov [DOE]

    Acquisition of a Natural Gas Pipeline and Natural Gas Utility Service at the Hanford Site, Richland, WA, and Notice of Floodplains and Wetlands Involvement

  6. Pseudobond parameters for QM/MM studies involving nucleosides, nucleotides, and their analogs

    SciTech Connect (OSTI)

    Chaudret, Robin; Parks, Jerry M; Yang, Weitao

    2013-01-01

    In biological systems involving nucleosides, nucleotides, or their respective analogs, the ribose sugar moiety is the most common reaction site, for example, during DNA replication and repair. How- ever, nucleic bases, which comprise a sizable portion of nucleotide molecules, are usually unreactive during such processes. In quantum mechanical/molecular simulations of nucleic acid reactivity, it may therefore be advantageous to describe specific ribosyl or ribosyl phosphate groups quantum me- chanically and their respective nucleic bases with a molecular mechanics potential function. Here, we have extended the pseudobond approach to enable quantum mechanical/molecular mechanical simulations involving nucleotides, nucleosides, and their analogs in which the interface between the two subsystems is located between the sugar and the base, namely, the C(sp3) N(sp2) bond. The pseudobond parameters were optimized on a training set of 10 molecules representing several nu- cleotide and nucleoside bases and analogs, and they were then tested on a larger test set of 20 diverse molecules. Particular emphasis was placed on providing accurate geometries and electrostatic prop- erties, including electrostatic potential, natural bond orbital (NBO) and atoms in molecules (AIM) charges and AIM first moments. We also tested the optimized parameters on five nucleotide and nu- cleoside analogues of pharmaceutical relevance and a small polypeptide (triglycine). Accuracy was maintained for these systems, which highlights the generality and transferability of the pseudobond approach. 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4772182

  7. Examining the consistency relations describing the three-point functions involving tensors

    SciTech Connect (OSTI)

    Sreenath, V.; Sriramkumar, L. E-mail: sriram@physics.iitm.ac.in

    2014-10-01

    It is well known that the non-Gaussianity parameter f{sub NL} characterizing the scalar bi-spectrum can be expressed in terms of the scalar spectral index in the squeezed limit, a property that is referred to as the consistency relation. In contrast to the scalar bi-spectrum, the three-point cross-correlations involving scalars and tensors and the tensor bi-spectrum have not received adequate attention, which can be largely attributed to the fact that the tensors had remained undetected at the level of the power spectrum until very recently. The detection of the imprints of the primordial tensor perturbations by BICEP2 and its indication of a rather high tensor-to-scalar ratio, if confirmed, can open up a new window for understanding the tensor perturbations, not only at the level of the power spectrum, but also in the realm of non-Gaussianities. In this work, we consider the consistency relations associated with the three-point cross-correlations involving scalars and tensors as well as the tensor bi-spectrum in inflationary models driven by a single, canonical, scalar field. Characterizing the cross-correlations in terms of the dimensionless non-Gaussianity parameters C{sub NL}{sup R} and C{sub NL}{sup γ} that we had introduced earlier, we express the consistency relations governing the cross-correlations as relations between these non-Gaussianity parameters and the scalar or tensor spectral indices, in a fashion similar to that of the purely scalar case. We also discuss the corresponding relation for the non-Gaussianity parameter h{sub NL} used to describe the tensor bi-spectrum. We analytically establish these consistency relations explicitly in the following two situations: a simple example involving a specific case of power law inflation and a non-trivial scenario in the so-called Starobinsky model that is governed by a linear potential with a sharp change in its slope. We also numerically verify the consistency relations in three types of inflationary models that permit deviations from slow roll and lead to scalar power spectra with features which typically result in an improved fit to the data than the more conventional, nearly scale invariant, spectra. We close with a summary of the results we have obtained.

  8. Pore scale modeling of reactive transport involved in geologic CO2 sequestration

    SciTech Connect (OSTI)

    Kang, Qinjin; Lichtner, Peter C; Viswanathan, Hari S; Abdel-fattah, Amr I

    2009-01-01

    We apply a multi-component reactive transport lattice Boltzmann model developed in previolls studies to modeling the injection of a C02 saturated brine into various porous media structures at temperature T=25 and 80 C. The porous media are originally consisted of calcite. A chemical system consisting of Na+, Ca2+, Mg2+, H+, CO2(aq), and CI-is considered. The fluid flow, advection and diHusion of aqueous species, homogeneous reactions occurring in the bulk fluid, as weB as the dissolution of calcite and precipitation of dolomite are simulated at the pore scale. The effects of porous media structure on reactive transport are investigated. The results are compared with continuum scale modeling and the agreement and discrepancy are discussed. This work may shed some light on the fundamental physics occurring at the pore scale for reactive transport involved in geologic C02 sequestration.

  9. Yellow affinity substance involved in the cellulolytic system of Clostridium thermocellum

    SciTech Connect (OSTI)

    Ljungdahl, L.G.; Pettersson, B.; Eriksson, K.E.; Wiegel, J.

    1983-01-01

    Clostridium thermocellum produces a yellow substance when fermenting cellulose. This substance is attached to the cellulose particles. Cellulose with the yellow substance, obtained from cultures of C. thermocellum, binds effectively endo-1,4-..beta..-glucanase produced by the bacterium and was used in an affinity column for purification of the enzyme. At the beginning of fermentation of cellulose, most of the endoglucanase was bound to the yellow cellulose. As the fermentation proceeded, the enzyme appeared free in the culture fluid. The endoglucanase bound to the yellow cellulose could be extracted by distilled water from the cellulose, but not by solutions with 5 mM or higher concentrations of salts or buffers. It is proposed that the yellow substance is involved in the cellulolytic system of C. thermocellum. 30 references, 3 figures, 3 tables.

  10. Success stories? an analysis of stakeholder involvement in the Department of Energy`s Office of Environmental Management

    SciTech Connect (OSTI)

    Beck, D.M.; Kelly, C.; Forbes, E.

    1995-12-01

    In several studies conducted by the Office of Environmental Management, the Department of Energy (DOE) has begun its first analysis of the benefits of stakeholder involvement. The studies seek to determine how public participation in DOE activities has contributed to cost savings, has changed the course of action for environmental projects, and has influenced the priorities of a national environmental program. This presentation will discuss the results and conclusions of following three studies: Stakeholder Survey of Trust and Confidence; the Success Stories study; and the Site-Specific Advisory Board Evaluation. These studies are taking their data from environmental management projects at Department of Energy sites throughout the United States. The studies of stakeholder involvement are currently analyzing the role of several variables in stakeholder involvement including the climate surrounding the environmental project or decision, the strategies used by DOE, the nature of the actual interactions, the attempts to reach consensus among interested parties, the role played by primary decision-makers, the goals set by the Department or by its stakeholders, and the revision of strategies during the stakeholder involvement process. Based on this analysis the planning and execution of future stakeholder involvement activities in Environmental Management will be improved. The study goal of establishing a set of factors that characterize successful stakeholder involvement within the Environmental Management program, will allow inference as to stakeholder involvement in other Federal and private environmental projects.

  11. Endovascular Treatment of Infrarenal Abdominal Aortic Lesions With or Without Common Iliac Artery Involvement

    SciTech Connect (OSTI)

    Oender, Hakan; Oguzkurt, Levent; Guer, Serkan; Tekbas, Gueven; Guerel, Kamil; Coskun, Isa; Oezkan, Ugur

    2013-02-15

    To evaluate the results of stent placement for obstructive atherosclerotic aortic disease with or without involvement of the common iliac artery. Forty patients had self-expanding stents primarily or after balloon dilatation in the abdominal aorta between January 2005 and May 2011. All patients had trouble walking. Follow-up examinations were performed with clinical visits; these included color Doppler ultrasonography and computed tomographic angiography. Technical, clinical, and hemodynamic success was achieved in all patients. None of the patients underwent reintervention during the follow-up period, which ranged from 3 months to 6 years (median 24 months). Nine complications occurred in six patients. Of the nine complications, four were distal thromboembolisms, which were successfully treated with catheter-directed thrombolysis or anticoagulation therapy. Endovascular treatment of the obstructive aortic disease using self-expanding stents was safe and effective, with high technical success and long-term patency. Thromboembolic complications were high even though direct stenting was considered protective for thromboembolism formation. Particularly for infrarenal aortic stenosis, it can be recommended as the first-line treatment option for patients with obstructive atherosclerotic aortic disease.

  12. Identification of a Xylogalacturonan Xylosyltransferase Involved in Pectin Biosynthesis in Arabidopsis

    SciTech Connect (OSTI)

    Pauly, Markus; Sorensen, Susanne Oxenboll; Harholt, Jesper; Geshi, Naomi; Sakuragi, Yumiko; Moller, Isabel; Zandleven, Joris; Bernal, Adriana J.; Jensen, Niels Bjerg; Sorensen, Charlotte; Jensen, Jacob K.; Beldman, Gerrit; Willats, William G.T.; Scheller, Henrik

    2009-08-19

    Xylogalacturonan (XGA) is a class of pectic polysaccharide found in plant cell walls. The Arabidopsis thaliana locus At5g33290 encodes a predicted Type II membrane protein, and insertion mutants of the At5g33290 locus had decreased cell wall xylose. Immunological studies, enzymatic extraction of polysaccharides, monosaccharide linkage analysis, and oligosaccharide mass profiling were employed to identify the affected cell wall polymer. Pectic XGA was reduced to much lower levels in mutant than in wild-type leaves, indicating a role of At5g33290 in XGA biosynthesis. The mutated gene was designated xylogalacturonan deficient1 (xgd1). Transformation of the xgd1-1 mutant with the wild-type gene restored XGA to wild-type levels. XGD1 protein heterologously expressed in Nicotiana benthamiana catalyzed the transfer of xylose from UDP-xylose onto oligogalacturonides and endogenous acceptors. The products formed could be hydrolyzed with an XGA-specific hydrolase. These results confirm that the XGD1 protein is a XGA xylosyltransferase. The protein was shown by expression of a fluorescent fusion protein in N. benthamiana to be localized in the Golgi vesicles as expected for a glycosyltransferase involved in pectin biosynthesis.

  13. Extension of DOE N 206.5, Response and Notification Procedures for Data Breaches Involving Personally Identifiable Information

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2008-10-09

    This Notice extends DOE N 206.5, Response and Notification Procedures for Data Breaches Involving Personally Identifiable Information, dated 10-9-07, until 1-9-09.

  14. Consent Versus Consensus - Stakehold Involvement in the Identification of Necessary and Sufficient Transportation

    SciTech Connect (OSTI)

    Fawcett, Ricky Lee; Kramer, George Leroy Jr.

    2003-03-01

    Transportation (DOT) and the Nuclear Regulatory Commission (NRC) to provide for the protection of the public and the environment; historically these regulations have proven quite sufficient. Even so, when the Department of Energy (DOE) makes radioactive materials shipments, that are deemed to be a major federal activity, regulations under the National Environmental Policy Act require that public input on safety issues be sought. This requirement leads to interactions with State, Tribal and local stakeholders that often result in the imposition of extra-regulatory requirements requirements beyond those prescribed by DOT and NRC regulations. Unfortunately, these additional requirements virtually always increase costs and delay schedules, and usually do so without significantly increasing, and possibly even decreasing overall transportation safety. We believe that this problem arises because of efforts to achieve stakeholder consensus rather than stakeholder consent, where consensus connotes universal agreement with all aspects of the program, while consent, as used here, is simple agreement with the overall course of action. Gaining consensus entails extensive negotiations because all aspects and requirements of the project must be agreed to by each stakeholder. Gaining consent, on the other hand, requires only that stakeholders be satisfied that the project, as planned, provides adequately for their safety needs. This article addresses the issue of consent versus consensus and proposes a systematic, decision science process for reaching consent. Key steps in this proposed process are early identification and involvement of stakeholders, compilation of their concerns, perceptions, needs, causes, and translation of that information into an appropriate set of derived requirements. These derived requirements, along with already-established DOT and NRC regulatory requirements, form the necessary and sufficient conditions for safe transportation and for obtaining stakeholder consent.

  15. Public Involvement Plan Public Involvement Plan

    Energy Savers [EERE]

    ... U.S. Environmental Protection Agency FFB 61 Forsyth Street S.W. Atlanta, GA 30303-3104 EPA Hotline: 1-800-241-1745 EPA Public Affairs Fax: (404) 562-8174 Web site: www.epa.gov...

  16. Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri

    SciTech Connect (OSTI)

    Houseworth, Jim; Rutqvist, Jonny; Asahina, Daisuke; Chen, Fei; Vilarrasa, Victor; Liu, Hui-Hai; Birkholzer, Jens

    2013-11-06

    Nuclear waste programs outside of the US have focused on different host rock types for geological disposal of high-level radioactive waste. Several countries, including France, Switzerland, Belgium, and Japan are exploring the possibility of waste disposal in shale and other clay-rich rock that fall within the general classification of argillaceous rock. This rock type is also of interest for the US program because the US has extensive sedimentary basins containing large deposits of argillaceous rock. LBNL, as part of the DOE-NE Used Fuel Disposition Campaign, is collaborating on some of the underground research laboratory (URL) activities at the Mont Terri URL near Saint-Ursanne, Switzerland. The Mont Terri project, which began in 1995, has developed a URL at a depth of about 300 m in a stiff clay formation called the Opalinus Clay. Our current collaboration efforts include two test modeling activities for the FE heater test and the HG-A leak-off test. This report documents results concerning our current modeling of these field tests. The overall objectives of these activities include an improved understanding of and advanced relevant modeling capabilities for EDZ evolution in clay repositories and the associated coupled processes, and to develop a technical basis for the maximum allowable temperature for a clay repository. The R&D activities documented in this report are part of the work package of natural system evaluation and tool development that directly supports the following Used Fuel Disposition Campaign (UFDC) objectives: ? Develop a fundamental understanding of disposal-system performance in a range of environments for potential wastes that could arise from future nuclear-fuel-cycle alternatives through theory, simulation, testing, and experimentation. ? Develop a computational modeling capability for the performance of storage and disposal options for a range of fuel-cycle alternatives, evolving from generic models to more robust models of performance assessment. For the purpose of validating modeling capabilities for thermal-hydro-mechanical (THM) processes, we developed a suite of simulation models for the planned full-scale FE Experiment to be conducted in the Mont Terri URL, including a full three-dimensional model that will be used for direct comparison to experimental data once available. We performed for the first time a THM analysis involving the Barcelona Basic Model (BBM) in a full three-dimensional field setting for modeling the geomechanical behavior of the buffer material and its interaction with the argillaceous host rock. We have simulated a well defined benchmark that will be used for codeto- code verification against modeling results from other international modeling teams. The analysis highlights the complex coupled geomechanical behavior in the buffer and its interaction with the surrounding rock and the importance of a well characterized buffer material in terms of THM properties. A new geomechanical fracture-damage model, TOUGH-RBSN, was applied to investigate damage behavior in the ongoing HG-A test at Mont Terri URL. Two model modifications have been implemented so that the Rigid-Body-Spring-Network (RBSN) model can be used for analysis of fracturing around the HG-A microtunnel. These modifications are (1) a methodology to compute fracture generation under compressive stress conditions and (2) a method to represent anisotropic elastic and strength properties. The method for computing fracture generation under compressive load produces results that roughly follow trends expected for homogeneous and layered systems. Anisotropic properties for the bulk rock were represented in the RBSN model using layered heterogeneity and gave bulk material responses in line with expectations. These model improvements were implemented for an initial model of fracture damage at the HG-A test. While the HG-A test model results show some similarities with the test observations, differences between the model results and observations remain.

  17. The Bond Between CO and Cp?3U in Cp?3U(CO) involves Backbondingfrom the

    Office of Scientific and Technical Information (OSTI)

    Cp'3U Ligand-based Orbitals of ?pi-Symmetry, where Cp' Represents a Substituted Cyclopentadienyl Ligand. (Journal Article) | SciTech Connect The Bond Between CO and Cp?3U in Cp?3U(CO) involves Backbondingfrom the Cp'3U Ligand-based Orbitals of ?pi-Symmetry, where Cp' Represents a Substituted Cyclopentadienyl Ligand. Citation Details In-Document Search Title: The Bond Between CO and Cp?3U in Cp?3U(CO) involves Backbondingfrom the Cp'3U Ligand-based Orbitals of ?pi-Symmetry, where Cp'

  18. 2013 Fuel Cycle Technologies Annual Review MeetingTransactions Report

    SciTech Connect (OSTI)

    Not Listed

    2013-11-01

    The Fuel Cycle Technologies (FCT) program of the Department of Energy (DOE) Office of Nuclear Energy (NE) is charged with identifying promising sustainable fuel cycles and developing strategies for effective disposition of used fuel and high-level nuclear waste, enabling policymakers to make informed decisions about these critical issues. Sustainable fuel cycles will improve uranium resource utilization, maximize energy generation while minimizing waste, improve safety, and limit proliferation risk. To achieve its mission, FCT has initiated numerous activities in each of the technical campaign areas, of which this report provides a sample.

  19. Electricity transactions across international borders, 1985. [With Mexico, Canada

    SciTech Connect (OSTI)

    Not Available

    1986-10-01

    This report summarizes the electricity exchange between the United States and Mexico and Canada during Calendar Year 1985. The construction, opration and maintenance of any electric transmission facility which crosses an international border of the United States requires a Presidential permit which has been granted by DOE. During 1985, the US imported 45,900,563 MWh of electric energy at a cost of $1,041,908,785. Of this total, 45,659,944 MWh were imported from Canada and the remainder (240,619 MWh) were received from Mexico. During this same period, US exports of electric energy totaled 4,964,930 MWh with gross revenues of $25,215,549. Of this, 4,812,537 MWh representing $22,068,665 in revenues were delivered to Canada, and 152,393 MWh representing $3,146,884 in revenues were delivered to Mexico. On a net basis, the US was an importer of 40,935,633 MWh of electric energy. These 1985 values constitute an increase of 8.1% in gross imports and an increase of 94.1% in gross exports compared to 1984 levels.

  20. Transactions of the nineteenth water reactor safety information meeting

    SciTech Connect (OSTI)

    Weiss, A.J.

    1991-10-01

    This report contains summaries of papers on reactor safety research to be presented at the 19th Water Reactor Safety Information Meeting at the Bethesda Marriott Hotel in Bethesda, Maryland, October 28--30, 1991. The summaries briefly describe the programs and results of nuclear safety research sponsored by the Office of Nuclear Regulatory Research, USNRC. Summaries of invited papers concerning nuclear safety issues from US government laboratories, the electric utilities, the Electric Power Research Institute (EPRI), the nuclear industry, and from the governments and industry in Europe and Japan are also included. The summaries have been compiled in one report to provide a basis for meaningful discussion and information exchange during the course of the meeting, and are given in the order of their presentation in each session. The individual summaries have been cataloged separately.

  1. Nature of Transactions (TI) Code | National Nuclear Security...

    National Nuclear Security Administration (NNSA)

    Blog Home About Us Our Programs Defense Nuclear Security Nuclear Materials Management & Safeguards System NMMSS ... U.S. Department of Energy U.S. Nuclear ...

  2. Commercial considerations in conversion and UF{sub 6} transactions

    SciTech Connect (OSTI)

    1994-02-01

    This article addresses various commercial considerations that result from the conversion of U3O8 into UF6 and the associated physical characteristics of natural UF6. Handling, transport, conversion, and enrichment of UF6 are discussed. Avenues of acquisition, including nation of origin, are also noted.

  3. Transaction-Based Operation of Resource Constrained Systems

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    VFD Fan Weather (optionally used to forecast PV output and weather-dependent loads) ... c urrent a nd f orecast p rices - Forecast p eriod a djustable ( e.g., h our a ...

  4. Capturing Energy Upgrades in the Real Estate Transaction

    Broader source: Energy.gov [DOE]

    Because green building techniques and products may impact the value of a home, they also affect the appraisal process when it comes to valuing residential properties. With the Cost Approach, the use of green features may increase the energy efficiency of a home but may add to the cost of that home’s reproduction or replacement. Appraisers employing the Cost Approach should look at how green features impact energy savings; how long a green product will last before it loses value; and if the use of green products (such as solar panels) detract from the curb appeal of the property.

  5. Fuel Cycle Technologies Annual Review Meeting Transactions Report

    SciTech Connect (OSTI)

    Lori Braase; W. Edgar May

    2014-11-01

    The Fuel Cycle Technologies (FCT) program supports the Department of Energys (DOEs) mission to: Enhance U.S. security and economic growth through transformative science, technology innovation, and market solutions to meet our energy, nuclear security, and environmental challenges. Goal 1 of DOEs Strategic Plan is to innovate energy technologies that enhance U.S. economic growth and job creation, energy security, and environmental quality. FCT does this by investing in advanced technologies that could transform the nuclear fuel cycle in the decades to come. Goal 2 of DOEs Strategic Plan is to strengthen national security by strengthening key science, technology, and engineering capabilities. FCT does this by working closely with the National Nuclear Security Administration and the U.S Department of State to develop advanced technologies that support the Nations nuclear nonproliferation goals.

  6. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    A M 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 4 1 31 20 -1405.00 -93.00 2 32 50 1042.00 03 31 ...

  7. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    A A 1 1 1 1 FOREIGN COMPANY NAME COMPANY ADDRESS CITY, COUNTRY CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 3 RRRR XXX 1 33 20 210.00 68.00 03 31 2008 1 ...

  8. Nuclear Material Transaction Report NRC 741_1

    National Nuclear Security Administration (NNSA)

    B 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 0 YYY XXX 04 01 2008 BASED ON SHIPPER'S VALUES Example ...

  9. Nuclear Material Transaction Report NRC 741_1

    National Nuclear Security Administration (NNSA)

    D 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 4 YYY XXX 1 31 20 -50397.00 -2335.00 2 31 20 50300.00 ...

  10. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    XXX VVV 000001 A A 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT WASTE COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 1 VVV XXX 03 31 2008 1 LD WASTE ...

  11. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    A A M 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 2 1 32 50 -1042.00 2 32 50 1002.00 03 31 2008 004 ...

  12. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    A B 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT FOREIGN COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 2 YYY RRRR 04 05 2008 1 AH31 1 EG 309 J ...

  13. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    A B 1 1 1 1 FOREIGN COMPANY NAME COMPANY ADDRESS CITY, COUNTRY CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 3 RRRR XXX 1 33 20 210.00 68.00 04 05 2008 1 ...

  14. Nuclear Material Transaction Report nrc741_1

    National Nuclear Security Administration (NNSA)

    A A 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT FOREIGN COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 2 YYY RRRR 03 31 2008 1 AH31 1 EG 309 J ...

  15. Nuclear Material Transaction Report NRC741_1

    National Nuclear Security Administration (NNSA)

    C 1 1 1 1 COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT COMPANY NAME COMPANY ADDRESS CITY, STATE ZIP CODE CONTACT 4 YYY XXX 1 31 20 -50397.00 -2335.00 2 31 20 50300.00 ...

  16. Transactive Controls R&D (Tx-R&D)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... and communication technologies (ICT). - Most common signal is economics based: ... ICT & related physical hardware) that allow applications to be programmed and negotiate...

  17. Transactions of the fifth symposium on space nuclear power systems

    SciTech Connect (OSTI)

    El-Genk, M.S.; Hoover, M.D.

    1988-01-01

    This paper contains the presented papers at the fourth symposium on space nuclear power systems. Topics of these paper include: space nuclear missions and applications, reactors and shielding, nuclear electric and nuclear propulsion, high-temperature materials, instrumentation and control, energy conversion and storage, space nuclear fuels, thermal management, nuclear safety, simulation and modeling, and multimegawatt system concepts. (LSP)

  18. Transactions of the fourth symposium on space nuclear power systems

    SciTech Connect (OSTI)

    El-Genk, M.S.; Hoover, M.D.

    1987-01-01

    This paper contains the presented papers at the fourth symposium on space nuclear power systems. Topics of these papers include: space nuclear missions and applications, reactors and shielding, nuclear electric and nuclear propulsion, refractory alloys and high-temperature materials, instrumentation and control, energy conversion and storage, space nuclear fuels, thermal management, nuclear safety, simulation and modeling, and multimegawatt system concepts. (LSP)

  19. Orange Button - Solar Bankability Data to Advance Transactions...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... The proposed project would seek to help integrate data standards across the life cycle of a solar project. SunSpec Alliance (Phase 2) Location: Santa Clara, CA SunShot Award ...

  20. ASHRAE transactions 1998. Volume 104, Part 1B: Symposium papers

    SciTech Connect (OSTI)

    1998-10-01

    This book covers the following topics; ground-source heat pumps; reflective roofs; heat transfer in special fenestration; space HVAC systems; thermal comfort; radiant heating and cooling; turbulent models for room airflow; durability of fenestration systems; seismic restraints for piping systems; new refrigerants and lubricants; thermal distributions systems; gas engine-driven heat pumps; European research on low-velocity measurements; absorption/sorption heat pumps and refrigeration systems; central heating plants with thermal energy storage; valves of hydronic pumping systems; air-to-air energy exchangers; fan/motor vibration problems in air-conditioning units; air cleaning in animal facilities; freezer entryways; heat gains and the new load calculation procedure; forced air-heating and cooling system performance in houses; and new water heating data, technologies and evaluation. Separate abstracts were prepared for most of the papers.

  1. Technical Meeting: Reference Guide for a Transaction-Based Building...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    efficient monitoring and controlling of plug loads, reduction of standby losses, detection of faulty devices, and demand response management CBERD: Integrated Sensors and Controls

  2. T.Rex Visual Analytics for Transactional Exploration

    ScienceCinema (OSTI)

    None

    2014-07-16

    T.Rex is PNNL's visual analytics tool that specializes in tabular structured data, like you might open with Excel. It's a client-server application, allowing the server to do a lot of the heavy lifting and the client to open spreadsheets with millions of rows. With datasets of that size, especially if you're unfamiliar with the contents, it's very hard to get a good grasp of what's in it using traditional tools. With T.Rex, the multiple views allow you to see categorical, temporal, numerical, relational, and summary data. The interactivity lets you look across your data and see how things relate to each other.

  3. Assistant Director, Credit Modeling and Transaction Risk Management Division

    Broader source: Energy.gov [DOE]

    The Risk Management Division (RMD) is the group within the U.S. Department of Energys Loan Program Office (LPO) that is responsible for oversight of all risks that have the potential to impede the...

  4. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health, Safety, Environmental Protection Chair 1 : Becky Holland 4 , Member Vice Chair 1 : Richard Bloom 4 , Alternate Committee Members 2 : Richard Bloom Becky Holland Antone Brooks Steve Hudson 4 Jan Catrell Mike Korenko Lynn Davison Bob Legard Sam Dechter Margery Swint Dirk Dunning Unofficial Committee Members or Other Interested Parties 3 : Pam Larsen Susan Leckband 4 Mike Priddy Facilitator: Cathy McCague 4 Agency & Technical Support: Kris Holmes 4 DOE-RL Beth Rochette 4 Ecology Dieter

  5. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    River and Plateau Committee Chair 1 : Pam Larsen 4 , Member Vice Chair 1 : Jan Catrell 4 , Alternate Committee Members 2 : Don Bouchey Liz Mattson Jan Catrell Emmett Moore Shelley Cimon Jerry Peltier Shannon Cram Gerry Pollet Rob Davis Ed Revell Dale Engstrom Dan Serres Gary Garnant Dick Smith Floyd Hodges Bob Suyama John Howieson Gene Van Liew Alex Klementiev Jean Vanni Pam Larsen Dawn Wellman Susan Leckband 4 Steve White Larry Lockrem Unofficial Committee Members or Other Interested Parties 3

  6. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tank Waste Committee Chair 1 : Bob Suyama 4 , Member Vice Chair 1 : Melanie Meyers 4 , Member Committee Members 2 : David Bernhard Pam Larsen Don Bouchey Larry Lockrem Amoret Bunn...

  7. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Budget and Contracts Committee Chair 1 : Jerry Peltier 4 , Member Vice Chair 1 : Ed Revell 4 , Member Committee Members 2 : Gary Garnant Gerry Pollet Susan Leckband 4 Ed Revell Ken...

  8. De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Cárdenas-Conejo, Yair; Carballo-Uicab, Víctor; Lieberman, Meric; Aguilar-Espinosa, Margarita; Comai, Luca; Rivera-Madrid, Renata

    2015-10-28

    Bixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L. An enzymatic pathway for bixin biosynthesis was inferred from homology of putative proteins encoded by differentially expressed seed cDNAs. Some activities were later validated in a heterologous system. Nevertheless, much of the pathway remains to be clarified. For example, it is essential to identify the methylerythritol phosphate (MEP) and carotenoid pathways genes. In order to investigate the MEP, carotenoid, and bixin pathways genes, total RNA from young leaves and two different developmental stages of seeds frommore » B. orellana were used for the construction of indexed mRNA libraries, sequenced on the Illumina HiSeq 2500 platform and assembled de novo using Velvet, CLC Genomics Workbench and CAP3 software. A total of 52,549 contigs were obtained with average length of 1,924 bp. Two phylogenetic analyses of inferred proteins, in one case encoded by thirteen general, single-copy cDNAs, in the other from carotenoid and MEP cDNAs, indicated that B. orellana is closely related to sister Malvales species cacao and cotton. Using homology, we identified 7 and 14 core gene products from the MEP and carotenoid pathways, respectively. Surprisingly, previously defined bixin pathway cDNAs were not present in our transcriptome. Here we propose a new set of gene products involved in bixin pathway. In conclusion, the identification and qRT-PCR quantification of cDNAs involved in annatto production suggest a hypothetical model for bixin biosynthesis that involve coordinated activation of some MEP, carotenoid and bixin pathway genes. These findings provide a better understanding of the mechanisms regulating these pathways and will facilitate the genetic improvement of B. orellana.« less

  9. Microsoft Word - PNNL 24125 Probative Investigation of the Thermal Stability of Wastes Involved in February 2014 WIPP Waste Dru

    Office of Environmental Management (EM)

    PART 970.doc Microsoft Word - PART 970.doc PDF icon Microsoft Word - PART 970.doc More Documents & Publications Searchable Electronic Department of Energy Acquisition Regulation Microsoft Word - Matrixpart2.doc AcqGuide70.52Matrixpart2Redo-OPAM

    PNNL-24125 Limited Distribution Probative Investigation of the Thermal Stability of Wastes Involved in February 2014 WIPP Waste Drum Breach Event March 2015 RD Scheele JM Schwantes BK McNamara MJ Minette DT Hobbs (SRNL) CA Barrett PNNL-24125

  10. Involved-Site Image-Guided Intensity Modulated Versus 3D Conformal Radiation Therapy in Early Stage Supradiaphragmatic Hodgkin Lymphoma

    SciTech Connect (OSTI)

    Filippi, Andrea Riccardo; Ciammella, Patrizia; Piva, Cristina; Ragona, Riccardo; Botto, Barbara; Gavarotti, Paolo; Merli, Francesco; Vitolo, Umberto; Iotti, Cinzia; Ricardi, Umberto

    2014-06-01

    Purpose: Image-guided intensity modulated radiation therapy (IG-IMRT) allows for margin reduction and highly conformal dose distribution, with consistent advantages in sparing of normal tissues. The purpose of this retrospective study was to compare involved-site IG-IMRT with involved-site 3D conformal RT (3D-CRT) in the treatment of early stage Hodgkin lymphoma (HL) involving the mediastinum, with efficacy and toxicity as primary clinical endpoints. Methods and Materials: We analyzed 90 stage IIA HL patients treated with either involved-site 3D-CRT or IG-IMRT between 2005 and 2012 in 2 different institutions. Inclusion criteria were favorable or unfavorable disease (according to European Organization for Research and Treatment of Cancer criteria), complete response after 3 to 4 cycles of an adriamycin- bleomycin-vinblastine-dacarbazine (ABVD) regimen plus 30 Gy as total radiation dose. Exclusion criteria were chemotherapy other than ABVD, partial response after ABVD, total radiation dose other than 30 Gy. Clinical endpoints were relapse-free survival (RFS) and acute toxicity. Results: Forty-nine patients were treated with 3D-CRT (54.4%) and 41 with IG-IMRT (45.6%). Median follow-up time was 54.2 months for 3D-CRT and 24.1 months for IG-IMRT. No differences in RFS were observed between the 2 groups, with 1 relapse each. Three-year RFS was 98.7% for 3D-CRT and 100% for IG-IMRT. Grade 2 toxicity events, mainly mucositis, were recorded in 32.7% of 3D-CRT patients (16 of 49) and in 9.8% of IG-IMRT patients (4 of 41). IG-IMRT was significantly associated with a lower incidence of grade 2 acute toxicity (P=.043). Conclusions: RFS rates at 3 years were extremely high in both groups, albeit the median follow-up time is different. Acute tolerance profiles were better for IG-IMRT than for 3D-CRT. Our preliminary results support the clinical safety and efficacy of advanced RT planning and delivery techniques in patients affected with early stage HL, achieving complete response after ABVD-based chemotherapy.

  11. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Ruben A. Abagyan, PhD

    2004-04-15

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  12. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Abagyan, Ruben; An, Jianghong

    2005-08-12

    DNA Damage Recognition and Repair (DDR&R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. We have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR&R process. The significant achievements of this project include: 1) Construction of the computational pipeline for searching DDR&R genes, building and validation of 3D models of proteins involved in DDR&R; 2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; and the development of a method to predict the effects of mutations. Large scale testing of technology to identify novel small binding pockets in protein structures leading to new DDRR inhibitor strategies 3) Improvements of macromolecular docking technology (see the CAPRI 1-3 and 4-5 results) 4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; 5) Construction and maintenance of the DNA Damage Recognition and Repair Database; 6) Producing 15 research papers (12 published and 3 in preparation).

  13. Activation of eNOS in endothelial cells exposed to ionizing radiation involves components of the DNA damage response pathway

    SciTech Connect (OSTI)

    Nagane, Masaki; Yasui, Hironobu; Sakai, Yuri; Yamamori, Tohru; Niwa, Koichi; Hattori, Yuichi; Kondo, Takashi; Inanami, Osamu

    2015-01-02

    Highlights: eNOS activity is increased in BAECs exposed to X-rays. ATM is involved in this increased eNOS activity. HSP90 modulates the radiation-induced activation of ATM and eNOS. - Abstract: In this study, the involvement of ataxia telangiectasia mutated (ATM) kinase and heat shock protein 90 (HSP90) in endothelial nitric oxide synthase (eNOS) activation was investigated in X-irradiated bovine aortic endothelial cells. The activity of nitric oxide synthase (NOS) and the phosphorylation of serine 1179 of eNOS (eNOS-Ser1179) were significantly increased in irradiated cells. The radiation-induced increases in NOS activity and eNOS-Ser1179 phosphorylation levels were significantly reduced by treatment with either an ATM inhibitor (Ku-60019) or an HSP90 inhibitor (geldanamycin). Geldanamycin was furthermore found to suppress the radiation-induced phosphorylation of ATM-Ser1181. Our results indicate that the radiation-induced eNOS activation in bovine aortic endothelial cells is regulated by ATM and HSP90.

  14. FBP-DOE PPPO 17Aug2012

    Energy Savers [EERE]

    FBP Update Impacts Of DOE Uranium Barter Program On U.S. Domestic Industry Fluor-B&W Portsmouth LLC April 1, 2014 Frank Hahne FBP advocates full appropriation funding for Portsmouth D&D; but continued DOE UF6 uranium barter sales if appropriations are not forthcoming - In FBP's analysis based on objective measures to date conclude that the U.S. uranium mining, conversion and enrichment industries have not experienced an adverse material impact from DOE's Uranium Barter Program...... *

  15. DNA rearrangement in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene

    SciTech Connect (OSTI)

    Tsujimoto, Y.; Bashir, M.M.; Givol, I.; Cossman, J.; Jaffe, E.; Croce, C.M.

    1987-03-01

    In most human lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2 gene and the minor one at 3' of the gene. Analysis of a panel of follicular lymphoma DNAs using probes for the first exon of the bcl-2 gene indicates that DNA rearrangements may also occur 5' to the involved bcl-2 gene. In this case the IgH locus and the bcl-2 gene are found in an order suggesting that an inversion also occurred during the translocation process. The coding region of the bcl-2 gene, however, are left intact in all cases of follicular lymphoma studied to date.

  16. DOE Technical Standards List. Directory of DOE and contractor personnel involved in non-government standards activities

    SciTech Connect (OSTI)

    1997-06-01

    This is a periodic report on the level of agency participation in non-Government standards activities. This technical standards list is intended to assist US Department of Energy (DOE) management and other personnel involved in the DOE technical Standards Program by identifying those participating individuals. The body of this document contains a listing of DOE employees and DOE contractors who have submitted a Record of Non-Government Standards Activity. Additional names were added from rosters supplied by non-Government standards bodies. Appendices to this document are provided to list the information by parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees.

  17. Expediting environmental cleanup--nationwide stakeholder involvement in U.S. Department of Energy`s plume focus area

    SciTech Connect (OSTI)

    McCabe, G.H.; Stein, S.L.; Serie, P.J.

    1995-12-01

    The U.S. Department of Energy (DOE) faces a major challenge in cleaning up its contaminated sites throughout the United States. One major area of concern is the plumes in soil and ground water, contaminated with a myriad of different pollutants. DOE recently established the Plume Focus Area to address these problems. The mission of the Plume Focus Area is to enhance the deployment of innovative technologies for containing and cleaning up contaminant plumes in ground water and soil at all DOE sites. By involving a range of stakeholders in the selection, demonstration, and evaluation of new technologies, the deployment of these technologies can be enhanced. Through this strategy, technology users join with other stakeholders to assess the appropriateness of new technologies for addressing plume contamination, and characterize the conditions under which those emerging technologies will be acceptable. If new plume cleanup technologies are to be deployable, they must improve on today`s baseline technologies. If sites and their stakeholders understood the technologies, recognize that their concerns are reflected in the evaluations and demonstrations, and participate in assessing how technology performance addresses their concerns, the likelihood of acceptance of those technologies is greater. Thus, broad stakeholder acceptance becomes part of the definition of an improved technology, evaluated in parallel with technical performance, cost, and other traditional parameters. This paper further describes the goals and objectives of the Plume Focus Area and emphasizes the importance of stakeholder involvement in achieving them. The process of coordinating with DOE sites is described to highlight how stakeholder input is considered throughout the Plume Focus Area decision-making process in selecting, developing, demonstrating, and evaluating innovative technologies to address plume problems.

  18. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    SciTech Connect (OSTI)

    Gemelli, Claudia; Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis

    2013-12-10

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling.

  19. Selection of potential IAEA inspection strategies involving cascade access at the Portsmouth Gas Centrifuge Enrichment Plant (GCEP)

    SciTech Connect (OSTI)

    Not Available

    1981-04-13

    This report has been prepared as a US contribution to Team 4 of the Hexapartite Safeguards Project. It provides to the Team 4 participants one example of an approach, which has been used in the United States, to developing a range of safeguards strategies involving differing degrees of access to cascade areas of centrifuge enrichment plants. Its purpose is to facilitate the work of other Hexapartite participants in completing Task II of Team 4's terms of reference. The scope of this report is limited to identifying safeguards approaches for the Portsmouth Gas Centrifuge Enrichment Plant (GCEP) which involve differing degrees of access to the cascade area. This report provides a method for selecting cascade access inspection strategies at GCEP which appear promising for more detailed evaluation. It is quite important to note, however, that the effectiveness and practicability of these strategies have not been established at the present. In addition, some strategies have been included on the basis of very preliminary calculations and considerations which have not been validated. Thus, some of these strategies may ultimately be rejected because they prove to be impracticable. Considerations of cost and the possible transfer of information and technology related to the production of enriched uranium will also be pertinent in considering the degrees and frequency of access to the cascade areas of centrifuge enrichment plants. This report describes the process for combining technical measures, implementation approaches and objectives to arrive at the total number of theoretically possible combinations. It then describes how these combinations may be reduced in a series of steps to a number that is more manageable for detailed evaluation. The process is shown schematically.

  20. David Henderson U.S. Depaiiment of Energy Office of Nuclear Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    a new Energy Resources International, Inc. ("ERI") report that examined the economic impact ... and barters in order to enhance ... achieved the objectives of the U.S. ...

  1. FBP-DOE PPPO 17Aug2012

    Office of Environmental Management (EM)

    Barter Program...... * Uranium Market Prices (Long Term & Spot) * Domestic Uranium ... Capital Expenditure decisions are made based on long- term U3O8 prices, not spot prices. ...

  2. Novel mechanism for scavenging of hypochlorite involving a periplasmic methionine-rich peptide and methionine sulfoxide reductase

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Melnyk, Ryan A.; Youngblut, Matthew D.; Clark, Iain C.; Carlson, Hans K.; Wetmore, Kelly M.; Price, Morgan N.; Lavarone, Anthony T.; Deutschbauer, Adam M.; Arkin, Adam P.; Coates, John D.

    2015-05-12

    Reactive chlorine species (RCS) defense mechanisms are important for bacterial fitness in diverse environments. In addition to the anthropogenic use of RCS in the form of bleach, these compounds are also produced naturally through photochemical reactions of natural organic matter and in vivo by the mammalian immune system in response to invading microorganisms. To gain insight into bacterial RCS defense mechanisms, we investigated Azospira suillum strain PS, which produces periplasmic RCS as an intermediate of perchlorate respiration. Our studies identified an RCS response involving an RCS stress-sensing sigma/anti-sigma factor system (SigF/NrsF), a soluble hypochlorite-scavenging methionine-rich periplasmic protein (MrpX), and amore » putative periplasmic methionine sulfoxide reductase (YedY1). We investigated the underlying mechanism by phenotypic characterization of appropriate gene deletions, chemogenomic profiling of barcoded transposon pools, transcriptome sequencing, and biochemical assessment of methionine oxidation. Our results demonstrated that SigF was specifically activated by RCS and initiated the transcription of a small regulon centering around yedY1 and mrpX. A yedY1 paralog (yedY2) was found to have a similar fitness to yedY1 despite not being regulated by SigF. Markerless deletions of yedY2 confirmed its synergy with the SigF regulon. MrpX was strongly induced and rapidly oxidized by RCS, especially hypochlorite. Our results suggest a mechanism involving hypochlorite scavenging by sacrificial oxidation of the MrpX in the periplasm. Reduced MrpX is regenerated by the YedY methionine sulfoxide reductase activity. The phylogenomic distribution of this system revealed conservation in several Proteobacteria of clinical importance, including uropathogenic Escherichia coli and Brucella spp., implying a putative role in immune response evasion in vivo. In addition, bacteria are often stressed in the environment by reactive chlorine species (RCS) of either anthropogenic or natural origin, but little is known of the defense mechanisms they have evolved. Using a microorganism that generates RCS internally as part of its respiratory process allowed us to uncover a novel defense mechanism based on RCS scavenging by reductive reaction with a sacrificial methionine-rich peptide and redox recycling through a methionine sulfoxide reductase. As a result, this system is conserved in a broad diversity of organisms, including some of clinical importance, invoking a possible important role in innate immune system evasion.« less

  3. Novel mechanism for scavenging of hypochlorite involving a periplasmic methionine-rich peptide and methionine sulfoxide reductase

    SciTech Connect (OSTI)

    Melnyk, Ryan A.; Youngblut, Matthew D.; Clark, Iain C.; Carlson, Hans K.; Wetmore, Kelly M.; Price, Morgan N.; Lavarone, Anthony T.; Deutschbauer, Adam M.; Arkin, Adam P.; Coates, John D.

    2015-05-12

    Reactive chlorine species (RCS) defense mechanisms are important for bacterial fitness in diverse environments. In addition to the anthropogenic use of RCS in the form of bleach, these compounds are also produced naturally through photochemical reactions of natural organic matter and in vivo by the mammalian immune system in response to invading microorganisms. To gain insight into bacterial RCS defense mechanisms, we investigated Azospira suillum strain PS, which produces periplasmic RCS as an intermediate of perchlorate respiration. Our studies identified an RCS response involving an RCS stress-sensing sigma/anti-sigma factor system (SigF/NrsF), a soluble hypochlorite-scavenging methionine-rich periplasmic protein (MrpX), and a putative periplasmic methionine sulfoxide reductase (YedY1). We investigated the underlying mechanism by phenotypic characterization of appropriate gene deletions, chemogenomic profiling of barcoded transposon pools, transcriptome sequencing, and biochemical assessment of methionine oxidation. Our results demonstrated that SigF was specifically activated by RCS and initiated the transcription of a small regulon centering around yedY1 and mrpX. A yedY1 paralog (yedY2) was found to have a similar fitness to yedY1 despite not being regulated by SigF. Markerless deletions of yedY2 confirmed its synergy with the SigF regulon. MrpX was strongly induced and rapidly oxidized by RCS, especially hypochlorite. Our results suggest a mechanism involving hypochlorite scavenging by sacrificial oxidation of the MrpX in the periplasm. Reduced MrpX is regenerated by the YedY methionine sulfoxide reductase activity. The phylogenomic distribution of this system revealed conservation in several Proteobacteria of clinical importance, including uropathogenic Escherichia coli and Brucella spp., implying a putative role in immune response evasion in vivo. In addition, bacteria are often stressed in the environment by reactive chlorine species (RCS) of either anthropogenic or natural origin, but little is known of the defense mechanisms they have evolved. Using a microorganism that generates RCS internally as part of its respiratory process allowed us to uncover a novel defense mechanism based on RCS scavenging by reductive reaction with a sacrificial methionine-rich peptide and redox recycling through a methionine sulfoxide reductase. As a result, this system is conserved in a broad diversity of organisms, including some of clinical importance, invoking a possible important role in innate immune system evasion.

  4. Visible light stimulating dual-wavelength emission and O vacancy involved energy transfer behavior in luminescence for coaxial nanocable arrays

    SciTech Connect (OSTI)

    Yang, Lei, E-mail: nanoyang@qq.com [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Hunan Province Key Laboratory for Spray Deposition Technology and Application, Hunan University, Changsha 410082 (China); Dong, Jiazhang; Jiang, Zhongcheng [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Pan, Anlian; Zhuang, Xiujuan [Key Laboratory for Micro-Nano Physics and Technology of Hunan Province, Hunan University, Changsha 410082 (China)

    2014-06-14

    We report a strategy to investigate O vacancy (V{sub O}) involved energy transfer and dual-wavelength yellow emission in coaxial nanocable. By electric field deposition and subsequent sol-gel template approach, ZnO:Tb/Y{sub 2}O{sub 3}:Eu coaxial nanocable arrays are synthesized. After visible light excitation, system is promoted to O vacancy charge transfer state of V{sub O}(0/+). In the following cross relaxation, energy transfer from V{sub O} to the excitation energy level of Tb{sup 3+} in ZnO:Tb core area. While in Y{sub 2}O{sub 3}:Eu shell area, energy transfer to the excitation energy level of Eu{sup 3+}. Subsequently, dual-wavelength emission is observed. By constructing nanocable with dual-wavelength emission, yellow luminescence is obtained. Adjust doping concentration of Eu{sup 3+} or Tb{sup 3+} in the range of 0.010.05, chromaticity coordinates of ZnO:Tb/Y{sub 2}O{sub 3}:Eu nanocable stably stays at yellow region in color space except ZnO:Tb{sub 0.01}/Y{sub 2}O{sub 3}:Eu{sub 0.01}. As Vo states act as media in energy transfer process in nanocablers, visible light can stimulate dual-wavelength emissions. Yellow luminescent nanocable arrays will have great applications in light-emitting diode luminescence.

  5. G-protein-coupled estrogen receptor 1 is involved in brain development during zebrafish (Danio rerio) embryogenesis

    SciTech Connect (OSTI)

    Shi, Yanan; Liu, Xiaochun; Zhu, Pei; Li, Jianzhen; Sham, Kathy W.Y.; Cheng, Shuk Han; Li, Shuisheng; Zhang, Yong; Cheng, Christopher H.K.; Lin, Haoran; College of Ocean, Hainan University, Haikou 570228, Hainan

    2013-05-24

    Highlights: •The Gper expression was detected in the developing brain of zebrafish. •Gper morpholino knockdown induced apoptosis of brain cells. •Gper morpholino knockdown reduced expression in neuron markers. •Zebrafish Gper may be involved in neuronal development. -- Abstract: G-protein-coupled estrogen receptor 1 (Gper, formerly known as GPR30) is found to be a trophic and protective factor in mediating action of estrogen in adult brain, while its role in developing brain remains to be elucidated. Here we present the expression pattern of Gper and its functions during embryogenesis in zebrafish. Both the mRNA and protein of Gper were detected throughout embryogenesis. Whole mount in situ hybridization (WISH) revealed a wide distribution of gper mRNAs in various regions of the developing brain. Gper knockdown by specific morpholinos resulted in growth retardation in embryos and morphological defects in the developing brain. In addition, induced apoptosis, decreased proliferation of the brain cells and maldevelopment of sensory and motor neurons were also found in the morphants. Our results provide novel insights into Gper functions in the developing brain, revealing that Gper can maintain the survival of the brain cells, and formation and/or differentiation of the sensory and motor neurons.

  6. Nuclear substructure reorganization during late stageerythropoiesis is selective and does not involve caspase cleavage ofmajor nuclear substructural proteins

    SciTech Connect (OSTI)

    Krauss, Sharon Wald; Lo, Annie J.; Short, Sarah A.; Koury, MarkJ.; Mohandas, Narla; Chasis, Joel Anne

    2005-04-06

    Enucleation, a rare feature of mammalian differentiation, occurs in three cell types: erythroblasts, lens epithelium and keratinocytes. Previous investigations suggest that caspase activation functions in lens epithelial and keratinocyte enucleation, as well as in early erythropoiesis encompassing BFU-E differentiation to proerythroblast. To determine whether caspase activation contributes to later erythropoiesis and whether nuclear substructures other than chromatin reorganize, we analyzed distributions of nuclear subcompartment proteins and assayed for caspase-induced cleavage of subcompartmental target proteins in mouse erythroblasts. We found that patterns of lamin B in the filamentous network interacting with both the nuclear envelope and DNA, nuclear matrix protein NuMA, and splicing factors Sm and SC35 persisted during nuclear condensation, consistent with effective transcription of genes expressed late in differentiation. Thus nuclear reorganization prior to enucleation is selective, allowing maintenance of critical transcriptional processes independent of extensive chromosomal reorganization. Consistent with these data, we found no evidence for caspase-induced cleavage of major nuclear subcompartment proteins during late erythropoiesis, in contrast to what has been observed in early erythropoiesis and in lens epithelial and keratinocyte differentiation. These findings imply that nuclear condensation and extrusion during terminal erythroid differentiation involve novel mechanisms that do not entail major activation of apoptotic machinery.

  7. H2-M polymorphism in mice susceptible to collagen-induced arthritis involves the peptide binding groove

    SciTech Connect (OSTI)

    Walter, W.; Loos, M.; Maeurer, M.J.

    1996-12-31

    The ability to develop type II collagen (CII)-induced arthritis (CIA) in mice is associated with the major histocompatibility I-A gene and with as yet poorly defined regulatory molecules of the major histocompatibility complex (MHC) class II antigen processing and presentation pathway. H2-M molecules are thought to be involved in the loading of antigenic peptides into the MHC class II binding cleft. We sequenced H2-Ma, H2-Mb1, and H2-Mb2 genes from CIA-susceptible and -resistant mouse strains and identified four different Ma and Mb2 alleles, and three different Mb1 alleles defined by polymorphic residues within the predicted peptide binding groove. Most CIA-resistant mouse strains share common Ma, Mb1, and Mb2 alleles. In contrast, H2-M alleles designated Ma-III, Ma-IV, Mb1-III, and Mb2-IV could be exclusively identified in the CIA-susceptible H2{sup r} and H2{sup q} haplotypes, suggesting that allelic H2-M molecules may modulate the composition of different CII peptides loaded onto MHC class II molecules, presumably presenting {open_quotes}arthritogenic{close_quotes} epitopes to T lymphocytes. 42 refs., 4 figs., 3 tabs.

  8. Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop

    SciTech Connect (OSTI)

    Lai, Serene R.; Cunningham, Amanda P.; Huynh, Vu Q.; Andrews, Lucy G.; Tollefsbol, Trygve O. . E-mail: trygve@uab.edu

    2007-01-15

    The human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the enzyme telomerase which is responsible for telomeric maintenance and extension. Using RNA interference to knock down hTERT mRNA expression, we provide evidence that hTERT exerts extra-telomeric effects on the cell cycle and on its own regulatory proteins, specifically: p53 and p21. We tested our hypothesis that hTERT regulates its own expression through effects on upstream regulatory genes using transformed human embryonic kidney (HEK 293) cells, p53 and p16 {sup INK4a} null human ovarian cancer SKOV-3 cells, and p53-null MDA-MB-157 human mammary cancer cells. In HEK 293 cells, hTERT knockdown resulted in elevated p53 and p21 transcription and a decrease in cellular proliferation. Similar results were observed in the MDA-MB-157 cell line where p21 was upregulated, correlating with cell growth inhibition. In contrast, we observed a decrease in expression of p21 in SKOV-3 cells with hTERT knockdown and cell growth appeared to be unaffected. These findings suggest that hTERT may be involved in a feedback loop system, thereby playing a role in its own regulation.

  9. Findings of an evaluation of public involvement programs associated with the development of a Land and Resource Management Plan for the Ouachita National Forest

    SciTech Connect (OSTI)

    Holthoff, M.G.; Howell, R.E.

    1993-08-01

    Federal regulations require the United States Forest Service (USFS) to integrate public input and values into decisions concerning land and resource management planning. The USFS has typically relied on traditional methods of involving the public, whereby public access and input to policy development are unilaterally controlled by the agency. Because of the highly political nature of land and resource management planning, such technocratic forms of public involvement and decision-making appear to be proving ineffective. This paper describes and evaluates two public involvement programs associated with the Ouachita National Forest`s (ONF) lengthy forest planning process. The research consisted of personal interviews with key program leaders and knowledgeable citizen participants, collection of secondary data, and a survey of citizen participants. Because of controversial planning decisions made during an initial planning process, the ONF was forced to re-enter the planning process in order to address unresolved planning issues and to conduct a more effective public involvement program. The supplemental planning process also resulted in a considerable degree of public contention. The survey revealed that although citizen participants were somewhat more satisfied with the supplemental public involvement program relative to the initial program, neither program was viewed as satisfactory. The findings of the study suggest that in order to be more effective, USFS public involvement programs should be more responsive to public concerns and conducted in adherence to principles of collaborative planning.

  10. Proteomic analysis reveals metabolic and regulatory systems involved in the syntrophic and axenic lifestyle of Syntrophomonas wolfei

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Sieber, Jessica R.; Crable, Bryan R.; Sheik, Cody S.; Hurst, Gregory B.; Rohlin, Lars; Gunsalus, Robert P.; McInerney, Michael J.

    2015-02-11

    We report that microbial syntrophy is a vital metabolic interaction necessary for the complete oxidation of organic biomass to methane in all-anaerobic ecosystems. However, this process is thermodynamically constrained and represents an ecosystem-level metabolic bottleneck. To gain insight into the physiology of this process, a shotgun proteomics approach was used to quantify the protein landscape of the model syntrophic metabolizer, Syntrophomonas wolfei, grown axenically and syntrophically with Methanospirillum hungatei. Remarkably, the abundance of most proteins as represented by normalized spectral abundance factor (NSAF) value changed very little between the pure and coculture growth conditions. Among the most abundant proteins detectedmore » were GroEL and GroES chaperonins, a small heat shock protein, and proteins involved in electron transfer, beta-oxidation, and ATP synthesis. Several putative energy conservation enzyme systems that utilize NADH and ferredoxin were present. The abundance of an EtfAB2 and the membrane-bound iron-sulfur oxidoreductase (Swol_0698 gene product) delineated a potential conduit for electron transfer between acyl-CoA dehydrogenases and membrane redox carriers. Proteins detected only when S. wolfei was grown with M. hungatei included a zinc-dependent dehydrogenase with a GroES domain, whose gene is present in genomes in many organisms capable of syntrophy, and transcriptional regulators responsive to environmental stimuli or the physiological status of the cell. In conclusion, the proteomic analysis revealed an emphasis on macromolecular stability and energy metabolism by S. wolfei and presence of regulatory mechanisms responsive to external stimuli and cellular physiological status.« less

  11. Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1

    SciTech Connect (OSTI)

    Kar, Rekha; Department of Biochemistry, UT Health Science Center at San Antonio, San Antonio, TX 78229 ; Mishra, Nandita; Singha, Prajjal K.; Venkatachalam, Manjeri A.; Department of Biochemistry, UT Health Science Center at San Antonio, San Antonio, TX 78229 ; Saikumar, Pothana

    2010-09-03

    Research highlights: {yields} Chemical inhibition of fission protein Drp1 leads to mitochondrial fusion. {yields} Increased fusion stimulates molecular changes in mitochondrial fusion protein OPA1. {yields} Proteolysis of larger isoforms, new synthesis and ubiquitination of OPA1 occur. {yields} Loss of mitochondrial tubular rigidity and disorganization of cristae. {yields} Generation of large swollen dysfunctional mitochondria. -- Abstract: We showed earlier that 15 deoxy {Delta}{sup 12,14} prostaglandin J2 (15d-PGJ2) inactivates Drp1 and induces mitochondrial fusion . However, prolonged incubation of cells with 15d-PGJ2 resulted in remodeling of fused mitochondria into large swollen mitochondria with irregular cristae structure. While initial fusion of mitochondria by 15d-PGJ2 required the presence of both outer (Mfn1 and Mfn2) and inner (OPA1) mitochondrial membrane fusion proteins, later mitochondrial changes involved increased degradation of the fusion protein OPA1 and ubiquitination of newly synthesized OPA1 along with decreased expression of Mfn1 and Mfn2, which likely contributed to the loss of tubular rigidity, disorganization of cristae, and formation of large swollen degenerated dysfunctional mitochondria. Similar to inhibition of Drp1 by 15d-PGJ2, decreased expression of fission protein Drp1 by siRNA also resulted in the loss of fusion proteins. Prevention of 15d-PGJ2 induced mitochondrial elongation by thiol antioxidants prevented not only loss of OPA1 isoforms but also its ubiquitination. These findings provide novel insights into unforeseen complexity of molecular events that modulate mitochondrial plasticity.

  12. An extracytoplasmic function sigma factor-dependent periplasmic glutathione peroxidase is involved in oxidative stress response of Shewanella oneidensis

    SciTech Connect (OSTI)

    Dai, Jingcheng; Wei, Hehong; Tian, Chunyuan; Damron, Fredrick; Zhou, Jizhong; Qiu, Dongru

    2015-01-01

    Background: Bacteria use alternative sigma factors (σs) to regulate condition-specific gene expression for survival and Shewanella harbors multiple ECF (extracytoplasmic function) σ genes and cognate anti-sigma factor genes. Here we comparatively analyzed two of the rpoE-like operons in the strain MR-1: rpoE-rseA-rseB-rseC and rpoE2-chrR. Results: RpoE was important for bacterial growth at low and high temperatures, in the minimal medium, and high salinity. The degP/htrA orthologue, required for growth of Escherichia coli and Pseudomonas aeruginosa at high temperature, is absent in Shewanella, while the degQ gene is RpoE-regulated and is required for bacterial growth at high temperature. RpoE2 was essential for the optimal growth in oxidative stress conditions because the rpoE2 mutant was sensitive to hydrogen peroxide and paraquat. The operon encoding a ferrochelatase paralogue (HemH2) and a periplasmic glutathione peroxidase (PgpD) was identified as RpoE2-dependent. PgpD exhibited higher activities and played a more important role in the oxidative stress responses than the cytoplasmic glutathione peroxidase CgpD under tested conditions. The rpoE2-chrR operon and the identified regulon genes, including pgpD and hemH2, are coincidently absent in several psychrophilic and/or deep-sea Shewanella strains. Conclusion: In S. oneidensis MR-1, the RpoE-dependent degQ gene is required for optimal growth under high temperature. The rpoE2 and RpoE2-dependent pgpD gene encoding a periplasmic glutathione peroxidase are involved in oxidative stress responses. But rpoE2 is not required for bacterial growth at low temperature and it even affected bacterial growth under salt stress, indicating that there is a tradeoff between the salt resistance and RpoE2-mediated oxidative stress responses.

  13. An extracytoplasmic function sigma factor-dependent periplasmic glutathione peroxidase is involved in oxidative stress response of Shewanella oneidensis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Dai, Jingcheng; Wei, Hehong; Tian, Chunyuan; Damron, Fredrick; Zhou, Jizhong; Qiu, Dongru

    2015-01-01

    Background: Bacteria use alternative sigma factors (σs) to regulate condition-specific gene expression for survival and Shewanella harbors multiple ECF (extracytoplasmic function) σ genes and cognate anti-sigma factor genes. Here we comparatively analyzed two of the rpoE-like operons in the strain MR-1: rpoE-rseA-rseB-rseC and rpoE2-chrR. Results: RpoE was important for bacterial growth at low and high temperatures, in the minimal medium, and high salinity. The degP/htrA orthologue, required for growth of Escherichia coli and Pseudomonas aeruginosa at high temperature, is absent in Shewanella, while the degQ gene is RpoE-regulated and is required for bacterial growth at high temperature. RpoE2 was essentialmore » for the optimal growth in oxidative stress conditions because the rpoE2 mutant was sensitive to hydrogen peroxide and paraquat. The operon encoding a ferrochelatase paralogue (HemH2) and a periplasmic glutathione peroxidase (PgpD) was identified as RpoE2-dependent. PgpD exhibited higher activities and played a more important role in the oxidative stress responses than the cytoplasmic glutathione peroxidase CgpD under tested conditions. The rpoE2-chrR operon and the identified regulon genes, including pgpD and hemH2, are coincidently absent in several psychrophilic and/or deep-sea Shewanella strains. Conclusion: In S. oneidensis MR-1, the RpoE-dependent degQ gene is required for optimal growth under high temperature. The rpoE2 and RpoE2-dependent pgpD gene encoding a periplasmic glutathione peroxidase are involved in oxidative stress responses. But rpoE2 is not required for bacterial growth at low temperature and it even affected bacterial growth under salt stress, indicating that there is a tradeoff between the salt resistance and RpoE2-mediated oxidative stress responses.« less

  14. The Impact of Extent and Location of Mediastinal Lymph Node Involvement on Survival in Stage III Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy

    SciTech Connect (OSTI)

    Fernandes, Annemarie T.; Mitra, Nandita; Xanthopoulos, Eric; Evans, Tracey; Stevenson, James; Langer, Corey; Kucharczuk, John C.; Lin, Lilie; Rengan, Ramesh

    2012-05-01

    Purpose: Several surgical series have identified subcarinal, contralateral, and multilevel nodal involvement as predictors of poor overall survival in patients with Stage III non-small-cell lung cancer (NSCLC) treated with definitive resection. This retrospective study evaluates the impact of extent and location of mediastinal lymph node (LN) involvement on survival in patients with Stage III NSCLC treated with definitive radiotherapy. Methods and Materials: We analyzed 106 consecutive patients with T1-4 N2-3 Stage III NSCLC treated with definitive radiotherapy at University of Pennsylvania between January 2003 and February 2009. For this analysis, mediastinal LN stations were divided into four mutually exclusive groups: supraclavicular, ipsilateral mediastinum, contralateral mediastinum, and subcarinal. Patients' conditions were then analyzed according to the extent of involvement and location of mediastinal LN stations. Results: The majority (88%) of patients received sequential or concurrent chemotherapy. The median follow-up time for survivors was 32.6 months. By multivariable Cox modeling, chemotherapy use (hazard ratio [HR]: 0.21 [95% confidence interval (CI): 0.07-0.63]) was associated with improved overall survival. Increasing primary tumor [18F]-fluoro-2-deoxy-glucose avidity (HR: 1.11 [CI: 1.06-1.19]), and subcarinal involvement (HR: 2.29 [CI: 1.11-4.73]) were significant negative predictors of overall survival. On univariate analysis, contralateral nodal involvement (HR: 0.70 [CI: 0.33-1.47]), supraclavicular nodal involvement (HR: 0.78 [CI: 0.38-1.67]), multilevel nodal involvement (HR: 0.97 [CI: 0.58-1.61]), and tumor size (HR: 1.04 [CI: 0.94-1.14]) did not predict for overall survival. Patients with subcarinal involvement also had lower rates of 2-year nodal control (51.2% vs. 74.9%, p = 0.047) and 2-year distant control (28.4% vs. 61.2%, p = 0.043). Conclusions: These data suggest that the factors that determine oncologic outcome in Stage III NSCLC patients treated with definitive radiotherapy are distinct from those observed in patients who undergo surgical resection. The ultimate efficacy of radiation in locally advanced NSCLC is dependent on the intrinsic biology of the tumor.

  15. An ortholog of farA of Aspergillus nidulans is implicated in the transcriptional activation of genes involved in fatty acid utilization in the yeast Yarrowia lipolytica

    SciTech Connect (OSTI)

    Poopanitpan, Napapol; Kobayashi, Satoshi; Fukuda, Ryouichi; Horiuchi, Hiroyuki; Ohta, Akinori

    2010-11-26

    Research highlights: {yields} POR1 is a Yarrowia lipolytica ortholog of farA involved in fatty acid response in A. nidulans. {yields} Deletion of POR1 caused growth defects on fatty acids. {yields} {Delta}por1 strain exhibited defects in the induction of genes involved in fatty acid utilization. -- Abstract: The yeast Yarrowia lipolytica effectively utilizes hydrophobic substrates such as fatty acids and n-alkanes. To identify a gene(s) regulating fatty acid utilization in Y. lipolytica, we first studied homologous genes to OAF1 and PIP2 of Saccharomyces cerevisiae, but their disruption did not change growth on oleic acid at all. We next characterized a Y. lipolytica gene, POR1 (primary oleate regulator 1), an ortholog of farA encoding a transcriptional activator that regulates fatty acid utilization in Aspergillus nidulans. The deletion mutant of POR1 was defective in the growth on various fatty acids, but not on glucose, glycerol, or n-hexadecane. It exhibited slight defect on n-decane. The transcriptional induction of genes involved in {beta}-oxidation and peroxisome proliferation by oleate was distinctly diminished in the {Delta}por1 strains. These data suggest that POR1 encodes a transcriptional activator widely regulating fatty acid metabolism in Y. lipolytica.

  16. B Decays Involving Light Mesons

    SciTech Connect (OSTI)

    Eschrich, Ivo Gough; /UC, Irvine

    2007-01-09

    Recent BABAR results for decays of B-mesons to combinations of non-charm mesons are presented. This includes B decays to two vector mesons, B {yields} {eta}{prime}({pi}, K, {rho}) modes, and a comprehensive Dalitz Plot analysis of B {yields} KKK decays.

  17. Cyber Incidents Involving Control Systems

    SciTech Connect (OSTI)

    Robert J. Turk

    2005-10-01

    The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this information available to Department of Homeland Security (DHS) and others who require it. This report summarizes the rise in frequency of cyber attacks, describes the perpetrators, and identifies the means of attack. This type of analysis, when used in conjunction with vulnerability analyses, can be used to support a proactive approach to prevent cyber attacks. CSSC will use this document to evolve a standardized approach to incident reporting and analysis. This document will be updated as needed to record additional event analyses and insights regarding incident reporting. This report represents 120 cyber security incidents documented in a number of sources, including: the British Columbia Institute of Technology (BCIT) Industrial Security Incident Database, the 2003 CSI/FBI Computer Crime and Security Survey, the KEMA, Inc., Database, Lawrence Livermore National Laboratory, the Energy Incident Database, the INL Cyber Incident Database, and other open-source data. The National Memorial Institute for the Prevention of Terrorism (MIPT) database was also interrogated but, interestingly, failed to yield any cyber attack incidents. The results of this evaluation indicate that historical evidence provides insight into control system related incidents or failures; however, that the limited available information provides little support to future risk estimates. The documented case history shows that activity has increased significantly since 1988. The majority of incidents come from the Internet by way of opportunistic viruses, Trojans, and worms, but a surprisingly large number are directed acts of sabotage. A substantial number of confirmed, unconfirmed, and potential events that directly or potentially impact control systems worldwide are also identified. Twelve selected cyber incidents are presented at the end of this report as examples of the documented case studies (see Appendix B).

  18. Who's Involved | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    2014 DOE CFC Campaign Leadership Chair Ernest Moniz, Secretary of Energy Vice Chair Dot Harris, Director, Office of Economic Impact and Diversity Champion David M. Klaus, Deputy...

  19. Safety Success Through Employee Involvement

    Broader source: Energy.gov [DOE]

    Presenters: James Pollard, Monica Lewis, Michael Hendrix, Stacy Miller, Y-12 National Security Complex Track 2-2

  20. Classified Visits Involving Foreign Nationals

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2004-01-13

    The Order establishes a program to manage the Department-wide program to facilitate, document, and assure accountability when approving foreign national access to classified DOE programs and facilities. Cancels portions of Chapter VIII, of DOE O 470.1 that pertain to foreign nationals who visit DOE sitess and require access to classified information. Canceled by DOE O 470.4B.

  1. Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos

    SciTech Connect (OSTI)

    Farhat, Amani; Buick, Julie K.; Williams, Andrew; Yauk, Carole L.; O'Brien, Jason M.; Crump, Doug; Williams, Kim L.; Chiu, Suzanne; Kennedy, Sean W.

    2014-03-01

    We previously demonstrated that in ovo exposure to the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) decreased plasma thyroxine levels, reduced growth parameters, and decreased gallbladder size in chicken embryos. In the current study DNA microarrays were used to evaluate global mRNA expression in liver tissue of male chicken embryos that exhibited the above mentioned effects. Injected doses were dimethyl sulfoxide vehicle control, 7.6 or 45 ?g TDCPP/g egg. TDCPP caused significant changes in the expression of five genes at the low dose and 47 genes at the high dose (False Discovery Rate p ? 0.1, fold change ? 1.5). The gene expression analysis suggested a compromised immune function, a state of cholestatic liver/biliary fibrosis, and disrupted lipid and steroid metabolism. Circulating bile acid levels were elevated, which is an indication of liver dysfunction, and plasma cholesterol levels were reduced; however, hepatic bile acid and cholesterol levels were unaltered. Interactome analyses identified apolipoprotein E, hepatocyte nuclear factor 4 alpha, and peroxisome proliferator-activated receptor alpha as key regulatory molecules involved in the effects of TDCPP. Our results demonstrate a targeted effect of TDCPP toxicity on lipid metabolism, including cholesterol, that helps explain the aforementioned phenotypic effects, as chicken embryos are highly dependent on yolk lipids for growth and maintenance throughout development. Finally, our results are in concordance with the literature that describes TDCPP as a cancer-causing agent, since the majority of dysregulated genes were involved in cancer pathways. - Highlights: TDCPP dysregulates genes involved in immune function and lipid metabolism. A targeted effect of TDCPP toxicity on cholesterol metabolism is apparent. A state of cholestatic liver fibrosis is suggested by the expression profile. Elevated plasma bile acids suggest that TDCPP causes liver dysfunction.

  2. Optimized Volumetric Modulated Arc Therapy Versus 3D-CRT for Early Stage Mediastinal Hodgkin Lymphoma Without Axillary Involvement: A Comparison of Second Cancers and Heart Disease Risk

    SciTech Connect (OSTI)

    Filippi, Andrea Riccardo; Ragona, Riccardo; Piva, Cristina; Scafa, Davide; Fiandra, Christian; Fusella, Marco; Giglioli, Francesca Romana; Lohr, Frank; Ricardi, Umberto

    2015-05-01

    Purpose: The purpose of this study was to evaluate the risks of second cancers and cardiovascular diseases associated with an optimized volumetric modulated arc therapy (VMAT) planning solution in a selected cohort of stage I/II Hodgkin lymphoma (HL) patients treated with either involved-node or involved-site radiation therapy in comparison with 3-dimensional conformal radiation therapy (3D-CRT). Methods and Materials: Thirty-eight patients (13 males and 25 females) were included. Disease extent was mediastinum alone (n=8, 21.1%); mediastinum plus unilateral neck (n=19, 50%); mediastinum plus bilateral neck (n=11, 29.9%). Prescription dose was 30 Gy in 2-Gy fractions. Only 5 patients had mediastinal bulky disease at diagnosis (13.1%). Anteroposterior 3D-CRT was compared with a multiarc optimized VMAT solution. Lung, breast, and thyroid cancer risks were estimated by calculating a lifetime attributable risk (LAR), with a LAR ratio (LAR{sub VMAT}-to-LAR{sub 3D-CRT}) as a comparative measure. Cardiac toxicity risks were estimated by calculating absolute excess risk (AER). Results: The LAR ratio favored 3D-CRT for lung cancer induction risk in mediastinal alone (P=.004) and mediastinal plus unilateral neck (P=.02) presentations. LAR ratio for breast cancer was lower for VMAT in mediastinal plus bilateral neck presentations (P=.02), without differences for other sites. For thyroid cancer, no significant differences were observed, regardless of anatomical presentation. A significantly lower AER of cardiac (P=.038) and valvular diseases (P<.0001) was observed for VMAT regardless of disease extent. Conclusions: In a cohort of patients with favorable characteristics in terms of disease extent at diagnosis (large prevalence of nonbulky presentations without axillary involvement), optimized VMAT reduced heart disease risk with comparable risks of thyroid and breast cancer, with an increase in lung cancer induction probability. The results are however strongly influenced by the different anatomical presentations, supporting an individualized approach.

  3. De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis

    SciTech Connect (OSTI)

    Cárdenas-Conejo, Yair; Carballo-Uicab, Víctor; Lieberman, Meric; Aguilar-Espinosa, Margarita; Comai, Luca; Rivera-Madrid, Renata

    2015-10-28

    Bixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L. An enzymatic pathway for bixin biosynthesis was inferred from homology of putative proteins encoded by differentially expressed seed cDNAs. Some activities were later validated in a heterologous system. Nevertheless, much of the pathway remains to be clarified. For example, it is essential to identify the methylerythritol phosphate (MEP) and carotenoid pathways genes. In order to investigate the MEP, carotenoid, and bixin pathways genes, total RNA from young leaves and two different developmental stages of seeds from B. orellana were used for the construction of indexed mRNA libraries, sequenced on the Illumina HiSeq 2500 platform and assembled de novo using Velvet, CLC Genomics Workbench and CAP3 software. A total of 52,549 contigs were obtained with average length of 1,924 bp. Two phylogenetic analyses of inferred proteins, in one case encoded by thirteen general, single-copy cDNAs, in the other from carotenoid and MEP cDNAs, indicated that B. orellana is closely related to sister Malvales species cacao and cotton. Using homology, we identified 7 and 14 core gene products from the MEP and carotenoid pathways, respectively. Surprisingly, previously defined bixin pathway cDNAs were not present in our transcriptome. Here we propose a new set of gene products involved in bixin pathway. In conclusion, the identification and qRT-PCR quantification of cDNAs involved in annatto production suggest a hypothetical model for bixin biosynthesis that involve coordinated activation of some MEP, carotenoid and bixin pathway genes. These findings provide a better understanding of the mechanisms regulating these pathways and will facilitate the genetic improvement of B. orellana.

  4. As you may kn&<' the~de&tment of &~er& (D&j 1s involved'in'a pronram

    Office of Legacy Management (LM)

    As you may kn&<' the~de&tment of &~er& (D&j 1s involved'in'a pronram '. to'chiiracterlze the radjologital cbndif~on of ,sites formerly used byythe . . . ., Manhattan Engineer Dlstrlct (NED) and/or Atomjc Energy Co$n~~lssiqq (AEC); in.. the development of 'nuclear energy.. As part..of this -programi' DOE is 1~ I+ preparing, ,a' series of. brJef~ summaries ,-of .the' history:. of' tho ,#D/AEC~ : : ..; 'i ..relatecl activities and 'Conditions at .thc. sneclfic. sites. The

  5. Synthesis and Application of an Environmentally Insensitive Cy3-Based Arsenical Fluorescent Probe to Identify Adaptive Microbial Responses Involving Proximal Dithiol Oxidation

    SciTech Connect (OSTI)

    Fu, Na; Su, Dian; Cort, John R.; Chen, Baowei; Xiong, Yijia; Qian, Weijun; Konopka, Allan; Bigelow, Diana J.; Squier, Thomas C.

    2013-03-06

    Reversible disulfide oxidation between proximal cysteines in proteins represents a common regulatory control mechanism to modulate flux through metabolic pathways in response to changing environmental conditions. To enable in vivo measurements of cellular redox changes linked to disulfide bond formation, we have synthesized a cell-permeable monosubstituted cyanine dye derivatized with arsenic (i.e., TRAP_Cy3) to trap and visualize dithiols in cytosolic proteins. Alkylation of reactive thiols prior to displacement of the bound TRAP-Cy3 by ethanedithiol permits facile protein capture and mass spectrometric identification of proximal reduced dithiols to the exclusion of individual cysteines. Applying TRAP_Cy3 to evaluate cellular responses to increases in oxygen and light levels in the photosynthetic microbe Synechococcus sp. PCC 7002, we observe large decreases in the abundance of reduced dithiols in cellular proteins, which suggest redox-dependent mechanisms involving the oxidation of proximal disulfides. Under these same growth conditions that result in the oxidation of proximal thiols, there is a reduction in the abundance of post-translational oxidative modifications involving nitrotyrosine and methionine sulfoxide formation. These results suggest that the redox status of proximal cysteines respond to environmental conditions, acting to regulate metabolic flux and minimize the formation of reactive oxygen species to decrease oxidative protein damage.

  6. Kinetics and dynamics of oxidation reactions involving adsorbed CO species on bulk supported Pt and copper oxides. Final project report, January 1, 1991--December 31, 1993

    SciTech Connect (OSTI)

    Conner, Wm.C.; Harold, M.

    1995-02-01

    This research was an integrated experimental and modeling study of oxidation reactions involving CO as a key player - be it a reactant, adsorbed intermediate, and/or partial oxidation product - in the catalytic sequence and chemistry. The reaction systems of interest in the project include CO, formaldehyde, and methanol oxidation by O{sub 2}, and CO oxidation by NO, on both Pt and copper oxide catalysts. These reactions are of importance in automobile exhaust catalysis. There is a paucity of rate data in the literature for these important environmental control reactions. A complicating factor is the propensity of these reactions to exhibit complex steady state and dynamic behavior, including multiple rate controlling steps, steady state multiplicity, and oscillatory phenomena. Such phenomena are rooted in some of the central issues of catalysis, including adsorbate interactions, and catalyst structural instabilities, such as surface reconstruction and surface chemical changes by oxidation- reduction. The goal of this research is to better understand the catalytic chemistry and kinetics of oxidations reactions involving CO as an adsorbed intermediate. Successfully meeting this goal requires an integration of basic kinetic measurements, in situ catalyst surface monitoring, kinetic modeling, and nonlinear mathematical tools. While the kinetics experiments have standard microreactor design, the potential for multiple and periodic rate states demands detailed procedures to pinpoint the bifurcation (ignition, extinction, Hopf) points. Kinetic models are constructed from rational mechanistic sequences and sound surface chemistry.

  7. Microenergetic research involving a coupled experimental and computational approach to evaluate microstructural effects on detonation and combustion at sub-millimeter geometries.

    SciTech Connect (OSTI)

    Nogan, John; Palmer, Jeremy Andrew; Brundage, Aaron L.; Long, Gregory T.; Wroblewski, Brian D.; Tappan, Alexander Smith; Renlund, Anita Mariana; Kravitz, Stanley H.; Baer, Melvin R.

    2006-07-01

    A new approach to explosive sample preparation is described in which microelectronics-related processing techniques are utilized. Fused silica and alumina substrates were prepared utilizing laser machining. Films of PETN were deposited into channels within the substrates by physical vapor deposition. Four distinct explosive behaviors were observed with high-speed framing photography by driving the films with a donor explosive. Initiation at hot spots was directly observed, followed by either energy dissipation leading to failure, or growth to a detonation. Unsteady behavior in velocity and structure was observed as reactive waves failed due to decreasing channel width. Mesoscale simulations were performed to assist in experiment development and understanding. We have demonstrated the ability to pattern these films of explosives and preliminary mesoscale simulations of arrays of voids showed effects dependent on void size and that detonation would not develop with voids below a certain size. Future work involves experimentation on deposited films with regular patterned porosity to elucidate mesoscale explosive behavior.

  8. The UV-absorber benzophenone-4 alters transcripts of genes involved in hormonal pathways in zebrafish (Danio rerio) eleuthero-embryos and adult males

    SciTech Connect (OSTI)

    Zucchi, Sara; Bluethgen, Nancy; Ieronimo, Andrea; Fent, Karl

    2011-01-15

    Benzophenone-4 (BP-4) is frequently used as UV-absorber in cosmetics and materials protection. Despite its frequent detection in the aquatic environment potential effects on aquatic life are unknown. In this study, we evaluate the effects of BP-4 in eleuthero-embryos and in the liver, testis and brain of adult male fish on the transcriptional level by focusing on target genes involved in hormonal pathways to provide a more complete toxicological profile of this important UV-absorber. Eleuthero-embryos and males of zebrafish were exposed up to 3 days after hatching and for 14 days, respectively, to BP-4 concentrations between 30 and 3000 {mu}g/L. In eleuthero-embryos transcripts of vtg1, vtg3, esr1, esr2b, hsd17ss3, cyp19b cyp19a, hhex and pax8 were induced at 3000 {mu}g/L BP-4, which points to a low estrogenic activity and interference with early thyroid development, respectively. In adult males BP-4 displayed multiple effects on gene expression in different tissues. In the liver vtg1, vtg3, esr1 and esr2b were down-regulated, while in the brain, vtg1, vtg3 and cyp19b transcripts were up-regulated. In conclusion, the transcription profile revealed that BP-4 interferes with the expression of genes involved in hormonal pathways and steroidogenesis. The effects of BP-4 differ in life stages and adult tissues and point to an estrogenic activity in eleuthero-embryos and adult brain, and an antiestrogenic activity in the liver. The results indicate that BP-4 interferes with the sex hormone system of fish, which is important for the risk assessment of this UV-absorber.

  9. Low-Dose Involved-Field Radiation in the Treatment of Non-Hodgkin Lymphoma: Predictors of Response and Treatment Failure

    SciTech Connect (OSTI)

    Russo, Andrea L.; Chen, Yu-Hui; Martin, Neil E.; Vinjamoori, Anant; Luthy, Sarah K.; Freedman, Arnold; Michaelson, Evan M.; Silver, Barbara; Mauch, Peter M.; Ng, Andrea K.

    2013-05-01

    Purpose: To investigate clinical and pathologic factors significant in predicting local response and time to further treatment after low-dose involved-field radiation therapy (LD-IFRT) for non-Hodgkin lymphoma (NHL). Methods and Materials: Records of NHL patients treated at a single institution between April 2004 and September 2011 were retrospectively reviewed. Low-dose involved-field radiation therapy was given as 4 Gy in 2 fractions over 2 consecutive days. Treatment response and disease control were determined by radiographic studies and/or physical examination. A generalized estimating equation model was used to assess the effect of tumor and patient characteristics on disease response. A Cox proportional hazards regression model was used to assess time to further treatment. Results: We treated a total of 187 sites in 127 patients with LD-IFRT. Histologies included 66% follicular, 9% chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma, 10% marginal zone, 6% mantle cell lymphoma (MCL), and 8% other. Median follow-up time was 23.4 months (range, 0.03-92.2 months). The complete response, partial response, and overall response rates were 57%, 25%, and 82%, respectively. A CLL histology was associated with a lower response rate (odds ratio 0.2, 95% confidence interval 0.1-0.5, P=.02). Tumor size, site, age at diagnosis, and prior systemic therapy were not associated with response. The median time to first recurrence was 13.6 months. Those with CLL and age ?50 years at diagnosis had a shorter time to further treatment for local failures (hazard ratio [HR] 3.63, P=.01 and HR 5.50, P=.02, respectively). Those with CLL and MCL had a shorter time to further treatment for distant failures (HR 11.1 and 16.3, respectively, P<.0001). Conclusions: High local response rates were achieved with LD-IFRT across most histologies. Chronic lymphocytic leukemia and MCL histologies and age ?50 years at diagnosis had a shorter time to further treatment after LD-IFRT.

  10. Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation

    SciTech Connect (OSTI)

    Hong, Wei; College of Basic Medicine, Tianjin Medical University, 300070 Tianjin ; Li, Jinru; Wang, Bo; Chen, Linfeng; Niu, Wenyan; Yao, Zhi; Baniahmad, Aria

    2011-12-02

    Highlights: Black-Right-Pointing-Pointer Corepressor Alien interacts with histone methyltransferase ESET in vivo. Black-Right-Pointing-Pointer Alien/ESET complex is recruited to nTRE of T3-responsive gene by liganded TR{beta}1. Black-Right-Pointing-Pointer ESET-mediated H3K9 methylation is required for liganded TR{beta}1-repressed transcription. Black-Right-Pointing-Pointer ESET is involved in T3-repressed G1/S phase transition and proliferation. -- Abstract: The ligand-bound thyroid hormone receptor (TR) is known to repress via a negative TRE (nTRE) the expression of E2F1, a key transcription factor that controls the G1/S phase transition. Alien has been identified as a novel interacting factor of E2F1 and acts as a corepressor of E2F1. The detailed molecular mechanism by which Alien inhibits E2F1 gene expression remains unclear. Here, we report that the histone H3 lysine 9 (H3K9) methyltransferase (HMT) ESET is an integral component of the corepressor Alien complex and the Alien/ESET complex is recruited to both sites, the E2F1 and the nTRE site of the E2F1 gene while the recruitment to the negative thyroid hormone response element (nTRE) is induced by the ligand-bound TR{beta}1 within the E2F1 gene promoter. We show that, overexpression of ESET promotes, whereas knockdown of ESET releases, the inhibition of TR{beta}1-regulated gene transcription upon T3 stimulation; and H3K9 methylation is required for TR{beta}1-repressed transcription. Furthermore, depletion of ESET impairs thyroid hormone-repressed proliferation as well as the G1/S transition of the cell cycle. Taken together, our data indicate that ESET is involved in TR{beta}1-mediated transcription repression and provide a molecular basis of thyroid hormone-induced repression of proliferation.

  11. EUCI Tribal and Indian Country Energy Development: Collaborating for Successful Transactions

    Broader source: Energy.gov [DOE]

    Hosted by the Electric Utility Consultants, Inc. (EUCI), this conference will provide practical tips for mutually beneficial collaboration between tribes and utility companies. The conference will focus on the fundamental concepts on how to network and collaborate in renewable energy such as solar, wind, biomass, and natural gas in Indian Country.

  12. Transactions of the Twenty-First Water Reactor Safety Information Meeting

    SciTech Connect (OSTI)

    Monteleone, S.

    1993-10-01

    This report contains summaries of papers on reactor safety research to be presented at the 21st Water Reactor Safety Information Meeting at the Bethesda Marriott Hotel, Bethesda, Maryland, October 25--27, 1993. The summaries briefly describe the programs and results of nuclear safety research sponsored by the Office of Nuclear Regulatory Research, US NRC. Summaries of invited papers concerning nuclear safety issues from US government laboratories, the electric utilities, the Electric Power Research Institute (EPRI), the nuclear industry, and from foreign governments and industry are also included. The summaries have been compiled in one report to provide a basis for meaningful discussion and information exchange during the course of the meeting and are given in the order of their presentation in each session.

  13. Transactions of the twenty-fifth water reactor safety information meeting

    SciTech Connect (OSTI)

    Monteleone, S.

    1997-09-01

    This report contains summaries of papers on reactor safety research to be presented at the 25th Water Reactor Safety Information Meeting at the Bethesda Marriott Hotel in Bethesda, Maryland, October 20--22, 1997. The summaries briefly describe the programs and results of nuclear safety research sponsored by the Office of Nuclear Regulatory Research, US NRC. Summaries of invited papers concerning nuclear safety issues from US government laboratories, the electric utilities, the nuclear industry, and from foreign governments and industry are also included. The summaries have been compiled in one report to provide a basis for meaningful discussion of information exchanged during the course of the meeting, and are given in order of their presentation in each session.

  14. Pathway to Fuel Cell Deployment--The 3rd Party Transaction: A...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    More Documents & Publications Biogas Markets and Federal Policy Biomass Program Perspectives on Anaerobic Digestion and Fuel Cell Integration at Biorefineries Biogas Technologies ...

  15. EUCI Tribal and Indian Country Energy Development: Collaborating for Successful Transactions

    Broader source: Energy.gov [DOE]

    Hosted by the Electric Utility Consultants, Inc. (EUCI), this conference will provide practical tips for mutually beneficial collaboration between tribes and utility companies. The conference will...

  16. Some remarks on antenna response in a reverberation chamber - Electromagnetic Compatibility, IEEE Transactions on

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ELECTROMAGNETIC COMPATIBILITY, VOL. 43, NO. 2, MAY 2001 239 Some Remarks on Antenna Response in a Reverberation Chamber L. K. Warne and K. S. H. Lee Abstract-The simple formula, = ( )( 8 ), for the received power of an antenna with a matched load in an over-moded cavity actually holds for an antenna of any shape and size. This can be seen from the close connection between the correlation tensor of the cavity field at two different points and the imaginary part of the free-space dyadic Green's

  17. Thermal and combined thermal and radiolytic reactions involving nitrous oxide, hydrogen, nitrogen, and ammonia in contact with tank 241-SY-101 simulated waste

    SciTech Connect (OSTI)

    Bryan, S.A.; Pederson, L.R.

    1996-02-01

    Work described in this report was conducted at Pacific Northwest National Laboratory (PNNL) for the Flammable Gas Safety Project, the purpose of which is to develop information needed to support Westinghouse Hanford Company (WHC) in their efforts to ensure the safe interim storage of wastes at the Hanford Site. Described in this report are the results of tests to evaluate the rates of thermal and combined thermal and radiolytic reactions involving flammable gases in the presence of Tank 241-SY-101 simulated waste. Flammable gases generated by the radiolysis of water and by the thermal and radiolytic decomposition of organic waste constituents may themselves participate in further reactions. Examples include the decomposition of nitrous oxide to yield nitrogen and oxygen, the reaction of nitrous oxide and hydrogen to produce nitrogen and water, and the reaction of nitrogen and hydrogen to produce ammonia. The composition of the gases trapped in bubbles in the wastes might therefore change continuously as a function of the time that the gas bubbles are retained.

  18. Analysis of the Salmonella regulatory network suggests involvement of SsrB and H-NS in σE-regulated SPI-2 gene expression

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Jie; Overall, Christopher C.; Nakayasu, Ernesto S.; Kidwai, Afshan S.; Jones, Marcus B.; Johnson, Rudd; Nguyen, Nhu T.; McDermott, Jason E.; Ansong, Charles; Heffron, Fred; et al

    2015-02-10

    The extracytoplasmic functioning sigma factor ?E is known to play an essential role for Salmonella enterica serovar Typhimurium to survive and proliferate in macrophages and mice. However, its regulatory network is not well characterized, especially during infection. Here we used microarray to identify genes regulated by ?E in Salmonella grown in three conditions: a nutrient-rich condition and two others that mimic early and late intracellular infection. We found that in each condition ?E regulated different sets of genes, and notably, several global regulators. When comparing nutrient-rich and infection-like conditions, large changes were observed in the expression of genes involved inmoreSalmonella pathogenesis island (SPI)-1 type-three secretion system (TTSS), SPI-2 TTSS, protein synthesis, and stress responses. In total, the expression of 58% of Salmonella genes was affected by ?E in at least one of the three conditions. An important finding is that ?E up-regulates SPI-2 genes, which are essential for Salmonella intracellular survival, by up-regulating SPI-2 activator ssrB expression at the early stage of infection and down-regulating SPI-2 repressor hns expression at a later stage. Moreover, ?E is capable of countering the silencing of H-NS, releasing the expression of SPI-2 genes. This connection between ?E and SPI-2 genes, combined with the global regulatory effect of ?E, may account for the lethality of rpoE-deficient Salmonella in murine infection.less

  19. t(8; 14) chromosome translocation of the Burkitt lymphoma cell line Daudi occurred during immunoglobulin gene rearrangement and involved the heavy chain diversity region

    SciTech Connect (OSTI)

    Haluska, F.G.; Tsujimoto, Y.; Croce, C.M.

    1987-10-01

    Recent molecular analyses of Burkitt lymphomas carrying the t(8;14) chromosome translocation have indicated that a dichotomy exists regarding the molecular mechanisms by which the translocations occur. Most sporadic Burkitt tumors carry translocations that apparently arise due to mistakes in the immunoglobulin isotype-switching process. In contrast, there is evidence that the translocations of most endemic Burkitt lymphomas occur as a consequence of aberrant V-D-J recombination of variable, diversity, and joining gene segments, catalyzed by the recombinase enzymes. This phenomenon was first noted in follicular lymphomas and chronic lymphocytic leukemias of the B-cell lineage and has been described in T-cell malignancies as well. In each of these cases, analysis of the nucleotide sequence at chromosome breakpoints demonstrated the involvement of immunoglobulin heavy chain J/sub H/ or T-cell-receptor ..cap alpha..-chain J..cap alpha.. gene segments in the translocation. The authors now have cloned and sequenced both the 8q- and 14q+ translocation breakpoints deriving from the t(8;14) translocation of the endemic Burkitt lymphoma line Daudi. The data show that the translocation resulted from a reciprocal exchange between the D/sub H/ region on chromosome 14 and sequences far 5' of the MYC protooncogene on chromosome 8. Features of the nucleotide sequences surrounding the breakpoint further implicate the V-D-J joining machinery in the genesis of chromosome translocation in endemic Burkitt lymphomas and, more generally, in other lymphoid malignancies as well.

  20. GABA/sub B/ receptor activation inhibits Ca/sup 2 +/-activated potassium channels in synaptosomes: involvement of G-proteins

    SciTech Connect (OSTI)

    Ticku, M.K.; Delgado, A.

    1989-01-01

    /sup 86/Rb-efflux assay from preloaded synaptosomes of rat cerebral cortex was developed to study the effect of GABA/sub B/ receptor agonist baclofen on Ca/sup 2 +/-activated K/sup +/-channels. Depolarization of /sup 86/Rb-loaded synaptosomes in physiological buffer increased Ca/sup 2 +/-activated /sup 86/Rb-efflux by 400%. The /sup 86/Rb-efflux was blocked by quinine sulfate, tetraethylammonium, and La/sup 3 +/ indicating the involvement of Ca/sup 2 +/-activated K/sup +/-channels. (-)Baclofen inhibited Ca/sup 2 +/-activated /sup 86/Rb-efflux in a stereospecific manner. The inhibitory effect of (-)baclofen was mediated by GABA/sub B/ receptor activation, since it was blocked by GABA/sub B/ antagonist phaclofen, but not by bicuculline. Further, pertussis toxin also blocked the ability of baclofen or depolarizing action to affect Ca/sup 2 +/-activated K/sup +/-channels. These results suggest that baclofen inhibits Ca/sup 2 +/-activated K/sup +/-channels in synaptosomes and these channels are regulated by G-proteins. This assay may provide an ideal in vitro model to study GABA/sub B/ receptor pharmacology.

  1. Nanowires, Capacitors, and Other Novel Outer-Surface Components Involved in Electron Transfer to Fe(III) Oxides in Geobacter Species

    SciTech Connect (OSTI)

    Lovley, Derek, R.

    2008-12-22

    The overall goal of this project was to better understand the mechanisms by which Geobacter species transfer electrons outside the cell onto Fe(III) oxides. The rationale for this study was that Geobacter species are often the predominant microorganisms involved in in situ uranium bioremediation and the growth and activity of the Geobacter species during bioremediation is primarily supported by electron transfer to Fe(III) oxides. These studies greatly expanded the understanding of electron transfer to Fe(III). Novel concepts developed included the potential role of microbial nanowires for long range electron transfer in Geobacter species and the importance of extracytoplasmic cytochromes functioning as capacitors to permit continued electron transfer during the hunt for Fe(III) oxide. Furthermore, these studies provided target sequences that were then used in other studies to tract the activity of Geobacter species in the subsurface through monitoring the abundance of gene transcripts of the target genes. A brief summary of the major accomplishments of the project is provided.

  2. Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB{sub 1} receptors and apoptotic cell death

    SciTech Connect (OSTI)

    Tomiyama, Ken-ichi; Funada, Masahiko

    2014-01-01

    The abuse of herbal products containing synthetic cannabinoids has become an issue of public concern. The purpose of this paper was to evaluate the acute cytotoxicity of synthetic cannabinoids on mouse brain neuronal cells. Cytotoxicity induced by synthetic cannabinoid (CP-55,940, CP-47,497, CP-47,497-C8, HU-210, JWH-018, JWH-210, AM-2201, and MAM-2201) was examined using forebrain neuronal cultures. These synthetic cannabinoids induced cytotoxicity in the forebrain cultures in a concentration-dependent manner. The cytotoxicity was suppressed by preincubation with the selective CB{sub 1} receptor antagonist AM251, but not with the selective CB{sub 2} receptor antagonist AM630. Furthermore, annexin-V-positive cells were found among the treated forebrain cells. Synthetic cannabinoid treatment induced the activation of caspase-3, and preincubation with a caspase-3 inhibitor significantly suppressed the cytotoxicity. These synthetic cannabinoids induced apoptosis through a caspase-3-dependent mechanism in the forebrain cultures. Our results indicate that the cytotoxicity of synthetic cannabinoids towards primary neuronal cells is mediated by the CB{sub 1} receptor, but not by the CB{sub 2} receptor, and further suggest that caspase cascades may play an important role in the apoptosis induced by these synthetic cannabinoids. In conclusion, excessive synthetic cannabinoid abuse may present a serious acute health concern due to neuronal damage or deficits in the brain. - Highlights: Synthetic cannabinoids (classical cannabinoids, non-classical cannabinoids, and aminoalkylindole derivatives) induce cytotoxicity in mouse forebrain cultures. Synthetic cannabinoid-induced cytotoxicity towards forebrain cultures is mediated by the CB{sub 1} receptor, but not by the CB{sub 2} receptor, and involves caspase-dependent apoptosis. A high concentration of synthetic cannabinoids may be toxic to neuronal cells that express CB{sub 1} receptors.

  3. Additional Survival Benefit of Involved-Lesion Radiation Therapy After R-CHOP Chemotherapy in Limited Stage Diffuse Large B-Cell Lymphoma

    SciTech Connect (OSTI)

    Kwon, Jeanny; Kim, Il Han; Kim, Byoung Hyuck; Kim, Tae Min; Heo, Dae Seog

    2015-05-01

    Purpose: The purpose of this study was to evaluate the role of involved-lesion radiation therapy (ILRT) after rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy in limited stage diffuse large B-cell lymphoma (DLBCL) by comparing outcomes of R-CHOP therapy alone with R-CHOP followed by ILRT. Methods and Materials: We identified 198 patients treated with R-CHOP (median, 6 cycles) for pathologically confirmed DLBCL of limited stage from July 2004 to December 2012. Clinical characteristics of these patients were 33% with stage I and 66.7% with stage II; 79.8% were in the low or low-intermediate risk group; 13.6% had B symptoms; 29.8% had bulky tumors (≥7 cm); and 75.3% underwent ≥6 cycles of R-CHOP therapy. RT was given to 43 patients (21.7%) using ILRT technique, which included the prechemotherapy tumor volume with a median margin of 2 cm (median RT dose: 36 Gy). Results: After a median follow-up of 40 months, 3-year progression-free survival (PFS) and overall survival (OS) were 85.8% and 88.9%, respectively. Multivariate analysis showed ≥6 cycles of R-CHOP (PFS, P=.004; OS, P=.004) and ILRT (PFS, P=.021; OS, P=.014) were favorable prognosticators of PFS and OS. A bulky tumor (P=.027) and response to R-CHOP (P=.012) were also found to be independent factors of OS. In subgroup analysis, the effect of ILRT was prominent in patients with a bulky tumor (PFS, P=.014; OS, P=.030) or an elevated level of serum lactate dehydrogenase (LDH; PFS, P=.004; OS, P=.012). Conclusions: Our results suggest that ILRT after R-CHOP therapy improves PFS and OS in patients with limited stage DLBCL, especially in those with bulky disease or an elevated serum LDH level.

  4. Epithelialmesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells

    SciTech Connect (OSTI)

    Ding, Song-Ze; Yang, Yu-Xiu; Li, Xiu-Ling; Michelli-Rivera, Audrey; Han, Shuang-Yin; Wang, Lei; Pratheeshkumar, Poyil; Wang, Xin; Lu, Jian; Yin, Yuan-Qin; Budhraja, Amit; Hitron, Andrew J.

    2013-05-15

    Hexavalent chromium [Cr(VI)] is an important human carcinogen associated with pulmonary diseases and lung cancer. Exposure to Cr(VI) induces DNA damage, cell morphological change and malignant transformation in human lung epithelial cells. Despite extensive studies, the molecular mechanisms remain elusive, it is also not known if Cr(VI)-induced transformation might accompany with invasive properties to facilitate metastasis. We aimed to study Cr(VI)-induced epithelialmesenchymal transition (EMT) and invasion during oncogenic transformation in lung epithelial cells. The results showed that Cr(VI) at low doses represses E-cadherin mRNA and protein expression, enhances mesenchymal marker vimentin expression and transforms the epithelial cell into fibroblastoid morphology. Cr(VI) also increases cell invasion and promotes colony formation. Further studies indicated that Cr(VI) uses multiple mechanisms to repress E-cadherin expression, including activation of E-cadherin repressors such as Slug, ZEB1, KLF8 and enhancement the binding of HDAC1 in E-cadherin gene promoter, but DNA methylation is not responsible for the loss of E-cadherin. Catalase reduces Cr(VI)-induced E-cadherin and vimentin protein expression, attenuates cell invasion in matrigel and colony formation on soft agar. These results demonstrate that exposure to a common human carcinogen, Cr(VI), induces EMT and invasion during oncogenic transformation in lung epithelial cells and implicate in cancer metastasis and prevention. - Graphical abstract: Epithelialmesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanisms in lung epithelial cells. - Highlights: We study if Cr(VI) might induce EMT and invasion in epithelial cells. Cr(VI) induces EMT by altering E-cadherin and vimentin expression. It also increases cell invasion and promotes oncogenic transformation. Catalase reduces Cr(VI)-induced EMT, invasion and transformation.

  5. Analysis of the Salmonella regulatory network suggests involvement of SsrB and H-NS in σE-regulated SPI-2 gene expression

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Li, Jie; Overall, Christopher C.; Nakayasu, Ernesto S.; Kidwai, Afshan S.; Jones, Marcus B.; Johnson, Rudd; Nguyen, Nhu T.; McDermott, Jason E.; Ansong, Charles; Heffron, Fred; et al

    2015-02-10

    The extracytoplasmic functioning sigma factor σE is known to play an essential role for Salmonella enterica serovar Typhimurium to survive and proliferate in macrophages and mice. However, its regulatory network is not well characterized, especially during infection. Here we used microarray to identify genes regulated by σE in Salmonella grown in three conditions: a nutrient-rich condition and two others that mimic early and late intracellular infection. We found that in each condition σE regulated different sets of genes, and notably, several global regulators. When comparing nutrient-rich and infection-like conditions, large changes were observed in the expression of genes involved inmore » Salmonella pathogenesis island (SPI)-1 type-three secretion system (TTSS), SPI-2 TTSS, protein synthesis, and stress responses. In total, the expression of 58% of Salmonella genes was affected by σE in at least one of the three conditions. An important finding is that σE up-regulates SPI-2 genes, which are essential for Salmonella intracellular survival, by up-regulating SPI-2 activator ssrB expression at the early stage of infection and down-regulating SPI-2 repressor hns expression at a later stage. Moreover, σE is capable of countering the silencing of H-NS, releasing the expression of SPI-2 genes. This connection between σE and SPI-2 genes, combined with the global regulatory effect of σE, may account for the lethality of rpoE-deficient Salmonella in murine infection.« less

  6. Breast Cancer Patients With 10 or More Involved Axillary Lymph Nodes Treated by Multimodality Therapy: Influence of Clinical Presentation on Outcome

    SciTech Connect (OSTI)

    Geara, Fady B. . E-mail: fg00@aub.edu.lb; Nasr, Elie; Tucker, Susan L.; Charafeddine, Maya; Dabaja, Bouthaina; Eid, Toufic; Abbas, Jaber; Salem, Ziad; Shamseddine, Ali; Issa, Philip; El Saghir, Nagi

    2007-06-01

    Purpose: To analyze tumor control and survival for breast cancer patients with 10 or more positive lymph nodes without systemic disease, treated by adjuvant radiation alone or combined-modality therapy. Methods and Materials: We reviewed the records of 309 consecutive patients with these characteristics who received locoregional radiotherapy (RT) at our institution. The majority of patients had clinical Stage II or IIIA-B disease (43% and 48%, respectively). The median number of positive axillary lymph nodes was 15 (range, 10-78). Adjuvant therapy consisted of RT alone, with or without chemotherapy, tamoxifen, and/or ovarian castration. Results: The overall 5-year and 10-year disease-free survival (DFS) rates were 20% and 7%, respectively. Median DFS was higher for patients with Stage I-II compared with those with Stage IIIABC (28 vs. 19 months; p = 0.006). Median DFS for patients aged {<=}35 years was lower than that of older patients (12 vs. 24 months; p < 0.0001). Patients treated with a combination therapy had a higher 5-year DFS rate compared with those treated by RT alone (26% vs. 11%; p 0.03). In multivariate analysis, clinical stage (III vs. I, II; relative risk = 1.8, p = 0.002) and age ({<=}35 vs. others; relative risk = 2.6, p <0.001) were found to be independent variables for DFS. Conclusion: This retrospective data analysis identified young age and advanced clinical stage as pertinent and independent clinical prognostic factors for breast cancer patients with advanced axillary disease (10 or more involved nodes). These factors can be used for further prognostic classification.

  7. SU-E-T-587: Monte Carlo Versus Ray-Tracing for Treatment Planning Involving CNS Tumors On the MultiPlan System for CyberKnife Radiosurgery

    SciTech Connect (OSTI)

    Forbang, R Teboh

    2014-06-01

    Purpose: MultiPlan, the treatment planning system for the CyberKnife Robotic Radiosurgery system offers two approaches to dose computation, namely Ray-Tracing (RT), the default technique and Monte Carlo (MC), an option. RT is deterministic, however it accounts for primary heterogeneity only. MC on the other hand has an uncertainty associated with the calculation results. The advantage is that in addition, it accounts for heterogeneity effects on the scattered dose. Not all sites will benefit from MC. The goal of this work was to focus on central nervous system (CNS) tumors and compare dosimetrically, treatment plans computed with RT versus MC. Methods: Treatment plans were computed using both RT and MC for sites covering (a) the brain (b) C-spine (c) upper T-spine (d) lower T-spine (e) L-spine and (f) sacrum. RT was first used to compute clinically valid treatment plans. Then the same treatment parameters, monitor units, beam weights, etc., were used in the MC algorithm to compute the dose distribution. The plans were then compared for tumor coverage to illustrate the difference if any. All MC calculations were performed at a 1% uncertainty. Results: Using the RT technique, the tumor coverage for the brain, C-spine (C3–C7), upper T-spine (T4–T6), lower T-spine (T10), Lspine (L2) and sacrum were 96.8%, 93.1%, 97.2%, 87.3%, 91.1%, and 95.3%. The corresponding tumor coverage based on the MC approach was 98.2%, 95.3%, 87.55%, 88.2%, 92.5%, and 95.3%. It should be noted that the acceptable planning target coverage for our clinical practice is >95%. The coverage can be compromised for spine tumors to spare normal tissues such as the spinal cord. Conclusion: For treatment planning involving the CNS, RT and MC appear to be similar for most sites but for the T-spine area where most of the beams traverse lung tissue. In this case, MC is highly recommended.

  8. Direct Involvement of ombB, omaB and omcB Genes in Extracellular Reduction of Fe(III) by Geobacter sulfurreducens PCA

    SciTech Connect (OSTI)

    Liu, Yimo; Fredrickson, Jim K.; Zachara, John M.; Shi, Liang

    2015-10-01

    The tandem gene clusters orfR-ombB-omaB-omcB and orfS-ombC-omaC-omcC of the metal-reducing bacterium Geobacter sulfurreducens PCA are responsible for trans-outer membrane electron transfer during extracellular reduction of Fe(III)-citrate and ferrihydrite [a poorly crystalline Fe(III) oxide]. Each gene cluster encodes a putative transcriptional factor (OrfR/OrfS), a porin-like outer-membrane protein (OmbB/OmbC), a periplasmic c-type cytochrome (c-Cyt, OmaB/OmaC) and an outer-membrane c-Cyt (OmcB/OmcC). The individual roles of OmbB, OmaB and OmcB in extracellular reduction of Fe(III), however, have remained either uninvestigated or controversial. Here, we showed that replacements of ombB, omaB, omcB and ombB-omaB with an antibiotic gene in the presence of ombC-omaC-omcC had no impact on reduction of Fe(III)-citrate by G. sulfurreducens PCA. Disruption of ombB, omaB, omcB and ombB-omaB in the absence of ombC-omaC-omcC, however, severely impaired the bacterial ability to reduce Fe(III)-citrate as well as ferrihydrite. These results unequivocally demonstrate an overlapping role of ombB-omaB-omcB and ombC-omaC-omcC in extracellular Fe(III) reduction by G. sulfurreducens PCA. Involvement of both ombB-omaB-omcB and ombC-omaC-omcC in extracellular Fe(III) reduction reflects the importance of these trans-outer membrane protein complexes in the physiology of this bacterium. Moreover, the kinetics of Fe(III)-citrate and ferrihydrite reduction by these mutants in the absence of ombC-omaC-omcC were nearly identical, which clearly show that OmbB, OmaB and OmcB contribute equally to extracellular Fe(III) reduction. Finally, orfS was found to have a negative impact on the extracellular reduction of Fe(III)-citrate and ferrihydrite in G. sulfurreducens PCA probably by serving as a transcriptional repressor.

  9. Amended Notice of Intent To Modify the Scope of the EIS and Conduct Additional Public Scoping Meetings, and Notice of Floodplains and Wetlands Involvement for the Northern Pass Project: Federal Register Notice VOlume 78, No. 173- September 6, 2013

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy announces its intent to modify the scope of the Northern Pass Transmission Line Project Environmental Impact Statement (DOE/EIS–0463) and to conduct additional public scoping meetings. Because the proposed Federal action may involve floodplains and wetlands, the draft EIS will include a floodplains and wetlands assessment as appropriate, and the final EIS and/or Record of Decision will include a floodplains and wetlands statement of findings.

  10. PSERC Webinar March 6, 2012

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... also serves as a reviewer for various journals including IEEE Transactions on Smart Grids, IEEE Transactions on Mobile computing, and IEEE Transactions on Wireless Communications. ...

  11. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    inquiry-based science activities. Sandia provides all materials and instructions (English and Spanish). For schools outside of our communities, we offer the following...

  12. Community Involvement Fund | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Requests for Proposals are issued at various times throughout the year. Eligible grantees include non-profit community organizations, groups, projects, or coalitions, who want to ...

  13. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Science Bowl is a Jeopardy-like event for high school and middle school students who have a strong interest and academic ability in mathematics and science. The Science Bowl ...

  14. SMR Handbook: Hybrid Energy Systems Involving SMRs

    SciTech Connect (OSTI)

    Shannon M. Bragg-Sitton

    2014-09-01

    Large-scale nuclear reactors are traditionally operated for a singular purpose: steady-state production of dispatchable baseload electricity that is distributed broadly on the electric grid. While this implementation is key to a sustainable, reliable energy grid, SMRs offer new opportunities for increased use of clean nuclear energy for both electric and thermal applications in more locations – while still accommodating the desire to support renewable production sources. This chapter considers a scenario in which renewable generation would be tightly coupled with the nuclear generation source – behind the grid – to meet the grid demand as an integrated energy system while simultaneously producing other commodities with the available thermal energy.

  15. Sandia National Laboratories: About Sandia: Community Involvement:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Programs: CroSSlinks Science Volunteers CroSSlinks Science Volunteers The CroSSlinks program, sponsored by Sandia and Lockheed Martin, links the science community with schools to improve science education for Albuquerque students. The program continues Sandia's commitment to the effective utilization of inquiry-based science instruction. Volunteers partner with teachers to advance the teaching of hands-on science in support of district standards and required curriculum. Science

  16. Public Involvement in the Environmental Assessment Process

    Broader source: Energy.gov [DOE]

    A DOE policy regarding the online publication and electronic notification of the availability of draft environmental assessments (EAs) for public comment.

  17. Decom project involves new tools, communication

    SciTech Connect (OSTI)

    1996-05-01

    This article is the May 1996 Power highlights. Included within this section are discussions of the following: (1) Ft. St. Vrain and Yankee Rowe decommissioning, (2) Stuck fuel assembly during refueling operations at PVNGS-2, (3) Restart schedules for Salem-1 & -2 and Indian Point-3, and (4) Reactor vessel annealing demonstration at Marble Hill.

  18. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science, Technology, Engineering, and Math Programs Future scientists photo Our science, technology, engineering, and math (STEM) programs engage students by linking science to the ...

  19. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cyber Technologies Academy CroSSlinks Science Volunteers DOE Regional Science Bowls Family Math Night Family Science Night Science, Technology, Engineering, and Math Programs ...

  20. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Math Night Family Math Night Family Math Night provides an evening of hands-on math activities held at local elementary schools. Students and parents work together on fun math ...

  1. Diet and Cancer Are Cooked Meats Involved

    ScienceCinema (OSTI)

    LLNL - University of California Television

    2009-09-01

    Diet has been associated with differences in cancer rates in human populations for many years. Mark Knize presents the latest research on cancer causes including work performed at Lawrence Livermore National Laboratory investigating some interesting chemical products created when meat is cooked and how to reduce them. Series: Science on Saturday [10/2006] [Health and Medicine] [Science] [Show ID: 11542

  2. TPA_Draft_Public_Involvement_Plan.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  3. UT gets involved at Oak Ridge

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The struggle to maintain the momentum built up winning World War II and to keep the scientific brain trust at the Clinton Laboratories built during that amazing world changing ...

  4. OREM continues involvement with workforce development program

    Broader source: Energy.gov [DOE]

    For the third consecutive year, OREM has partnered with the NNSA to participate in a 10-week workforce development program for college interns.

  5. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Awards reward young people who, through hard work and determination, overcome great personal difficulties to achieve their goals. Their achievements earn them roles as leaders...

  6. Local employee honored for community involvement

    Broader source: Energy.gov [DOE]

    Last month, the East Tennessee Economic Council (ETEC) recognized Colin Colverson, an Energy Department attorney in Oak Ridge, with the prestigious Postma Young Professional Medal. The selection committee chooses an annual recipient for the award that displays elite community service and leadership qualities.

  7. RAPID/Get Involved | Open Energy Information

    Open Energy Info (EERE)

    join us as a contributor or attend one of our upcoming meetings. Be a Contributor Update.jpg RAPID OpenEI Tutorial.pdf Please feel free to log in to OpenEI and make content...

  8. Strategic Public Involvement … Tool Time!

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Liz Mattson, Hanford Challenge Engage the public early and often. Educate the public by providing timely, accurate, and understandable information. Incorporate public values in the decision making process and in the decisions made. Prepare future generations for informed engagement and participation. Ice Cream Socials Build a sense of community around Hanford (locally, regionally, and beyond). Ice Cream Socials  Organize Event: › Located in a place people are already gathering › Provide

  9. Department of Energy Idaho - Public Involvement Opportunity

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    If you experience problems in reading the files please down load the latest free Adobe ... Environmental Checklist -2 Mb Battelle Energy Alliance, LLC Response to Department of ...

  10. Mound Site Community Involvement Plan 2012

    Office of Legacy Management (LM)

    ... National Oil and Hazardous Substances Pollution Contingency Plan (NCP), codified at ... Universities and other research parks are close by, as well as the Wright Patterson Air ...

  11. Accurate Numerical Simulations Of Chemical Phenomena Involved...

    Office of Scientific and Technical Information (OSTI)

    Authors: Harrison, R.J. ; Vzquez-Mayagoitia, A. ; Hammond, J.R. 1 ; Stony Brook University) 2 + Show Author Affiliations (LCF) LCF ( Publication Date: 2013-09-16 OSTI ...

  12. Public Involvement and Communications Committee - Transcribed...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and implications o Focus on progress o Explain outcomes of CD when available Page 1 Lessons Learned Start with LCD (general public that doesn't know anything about...

  13. Sandia National Laboratories: About Sandia: Community Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    passionate about volunteering. You'll find Sandians judging science fairs, coaching sports teams, leading scouting troops, sorting food, building houses, and serving on...

  14. Sandia National Laboratories: About Sandia: Community Involvement...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    gifts to nearly 500 needy families. A unique giving program at Sandia is our on-site, blood drives. These convenient drives facilitate the donation of over 900 units of blood...

  15. Fukushima Media Involvement: Lessons Learned and Challenges

    SciTech Connect (OSTI)

    Harvey, Geoffrey L.; Koller, Greg L.; Johnson, Wayne L.

    2013-04-01

    Only days after the Fukushima nuclear reactor disaster on March 11, 2011, the Department of Energy’s Pacific Northwest National Laboratory, or PNNL, found itself in a maelstrom of media attention following announcement of the detection of minute levels of radioactive material originating from the damaged reactors 4,500 miles away. Within days, PNNL had set up a technical team in support of the U.S. government’s efforts to assist the devastated country. While a vast amount of information began to flow from Japan, the situation rapidly evolved challenging PNNL scientists and engineers, as well as news media and the general public to deal with a complex and often conflicting information stream. Over the course of about three weeks, PNNL’s News & Media Relations staff and its scientists and engineers responded to more than one hundred requests for information, and engaged in dozens of personal interviews with international, national, regional and local media. While many of the interviews and resulting stories were accurate and well done, to say that all communication went flawless would be far from the truth. In the midst of chaos and confusion, which are part of any significant crisis, hiccoughs are sure to occur. Even when communications guidelines are established and agreed-to ahead of time, and spokespeople promise to stay on message and within their areas of expertise, there is no guarantee the ball will not be dropped on occasion. Addressed here is “the rest of the story.”

  16. Accurate Numerical Simulations Of Chemical Phenomena Involved...

    Office of Scientific and Technical Information (OSTI)

    A paper copy of this document is also available for sale to the public from the National Technical Information Service, Springfield, VA at www.ntis.gov. Authors: Harrison, R.J. ; ...

  17. Waiver of Mandatory Use of the Strategic Integrated Procurement Enterprise System (STRIPES) for GSA Global Supply Service Transactions

    Broader source: Energy.gov [DOE]

    Pursuant to Federal Acquisition Regulation (FAR) 8.402 (c)(1), orders placed through the General Service Administration (GSA) Global Supply System are not subject to FAR Subpart 8.4, Federal Supply Schedules. In addition, FAR 4.606 (c)(2) eliminates the requirement for orders from GSA Global Supply System be reported to the Federal Procurement Data System – Next Generation (FPDS-NG).

  18. Market power, affiliate transactions, and state regulation of public utility holding companies: Remembering the past, looking to the future

    SciTech Connect (OSTI)

    Glazer, C.A.

    1996-11-01

    In examining the workings of the Public Utility Holding Company Act (PUHCA) and considering its possible repeal, it is best to go back to the original purposes of PUHCA and analyze whether those purposes are still relevant and, if so, whether the 1935 Act accomplished its goal. Indeed, one might ask, {open_quotes}Are the abuses which gave rise to PUHCA back in the 1930`s now eradicated such that outright repeal is warranted?{close_quotes} One is reminded of that old quote from Santayana, {open_quotes}Those who cannot remember the past are condemned to repeat it.{close_quotes} There is not a more appropriate time to heed that saying than now. To lay the foundation, we need to step back in time and place ourselves in the shoes of the policy makers at the time that PUHCA was debated.

  19. The Department of Energy has opted to utilize the following agreement for Designated Non-Proprietary User Facilities transactions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Celebrates LGBTQ Pride The Department of Energy Celebrates LGBTQ Pride June 17, 2015 - 5:54pm Addthis Watch the video of the entire LGBTQ program held June 15, 2015 at the Department of Energy. | Video courtesy of the Energy Department. Tre Easton Tre Easton Special Assistant to the Assistant Secretary, Office of Congressional and Intergovernmental Affairs Tre Easton, Special Assistant to the Assistant Secretary in the Office of Congressional and Intergovernmental Affairs, gave opening remarks

  20. Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Luo, Fei; Xu, Yuan; Ling, Min; Zhao, Yue; Xu, Wenchao; Liang, Xiao; Jiang, Rongrong; Wang, Bairu; Bian, Qian; Liu, Qizhan

    2013-11-15

    Arsenite is an established human carcinogen, and arsenite-induced inflammation contributes to malignant transformation of cells, but the molecular mechanisms by which cancers are produced remain to be established. The present results showed that, evoked by arsenite, secretion of interleukin-6 (IL-6), a pro-inflammatory cytokine, led to the activation of STAT3, a transcription activator, and to increased levels of a microRNA, miR-21. Blocking IL-6 with anti-IL-6 antibody and inhibiting STAT3 activation reduced miR-21 expression. For human bronchial epithelial cells, cultured in the presence of anti-IL-6 antibody for 3 days, the arsenite-induced EMT and malignant transformation were reversed. Thus, IL-6, acting on STAT3 signaling, which up-regulates miR-21in an autocrine manner, contributes to the EMT induced by arsenite. These data define a link from inflammation to EMT in the arsenite-induced malignant transformation of HBE cells. This link, mediated through miRNAs, establishes a mechanism for arsenite-induced lung carcinogenesis. - Highlights: Arsenite evokes IL-6 secretion. IL-6 autocrine mediates STAT3 signaling and up-regulates miR-21expression. Inflammation is involved in arsenite-induced EMT.

  1. May market review. [Spot market prices for uranium (1993)

    SciTech Connect (OSTI)

    Not Available

    1993-06-01

    Seven uranium transactions totalling nearly three million pounds equivalent U3O8 were reported during May, but only two, totalling less than 200 thousand pounds equivalent U3O8, involved concentrates. As no discretionary buying occurred during the month, and as near-term supply and demand were in relative balance, prices were steady, while both buyers and sellers appeared to be awaiting some new market development to signal the direction of future spot-market prices. The May 31, 1993, Exchange Value and the Restricted American market Penalty (RAMP) for concentrates were both unchanged at $7.10, and $2.95 per pound U3O8, respectively. NUEXCO's judgement was that transactions for significant quantities of uranium concentrates that were both deliverable in and intended for consumption in the USA could have been concluded on May 31 at $10.05 per pound U3O8. Two near-term concentrate transactions were reported in which one US utility purchased less than 200 thousand pounds equivalent U3O8 from two separate sellers. These sales occurred at price levels at or near the May 31 Exchange Value plus RAMP. No long-term uranium transactions were reported during May. Consequently, the UF6 Value decreased $0.20 to $24.30 per kgU as UF6, reflecting some weakening of the UF6 market outside the USA.

  2. Electric trade in the United States, 1996

    SciTech Connect (OSTI)

    1998-12-01

    Wholesale trade in electricity plays an important role for the US electric utility industry. Wholesale, or bulk power, transactions allow electric utilities to reduce power costs, increase power supply options, and improve reliability. In 1996, the wholesale trade market totaled 2.3 trillion kilowatthours, over 73% of total sales to ultimate consumers. This publication, Electric Trade in the United States 1996 (ELECTRA), is the sixth in a series of reports on wholesale power transactions prepared by the Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA). The electric trade data are published biennially. The first report presented 1986 data, and this report provides information on the electric power industry during 1996. The electric trade data collected and presented in this report furnish important information on the wholesale structure found within the US electric power industry. The patterns of interutility trade in the report support analyses of wholesale power transactions and provide input for a broader understanding of bulk power market issues that define the emerging national electric energy policies. The report includes information on the quantity of power purchased, sold, exchanged, and wheeled; the geographical locations of transactions and ownership classes involved; and the revenues and costs. 1 fig., 43 tabs.

  3. H.R. 5299: A Bill to amend the Internal Revenue Code of 1986 to phase out the tax subsidies for alcohol fuels involving alcohol produced from feedstocks eligible to receive Federal agricultural subsidies. Introduced in the House of Representatives, One Hundred Third Congress, Second Session, November 29, 1994

    SciTech Connect (OSTI)

    1994-12-31

    The report H.R. 5299 is a bill to amend the Internal Revenue Code of 1986 to phase out the tax subsidies of alcohol fuels involving alcohol produced from feedstocks eligible to receive Federal agriculture subsidies. The proposed legislative text is included.

  4. Chapter 06 - Cash

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    . Cash 6-1 CHAPTER 6 CASH 1. INTRODUCTION. a. Purpose. This chapter provides Departmental procedures and policy for handling cash and transactions in which cash is involved. It supplements the Treasury Financial Manual (TFM) and the Department of the Treasury (Treasury) Financial Management Service's (FMS) supplement to the TFM, "Cash Management Made Easy." Additional information is available on the FMS website at www.fms.treas.gov. b. Applicability. The applicability of this chapter

  5. Degradation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Definitions Definitions Personal Property Definitions and Acronyms Definitions Acronyms Definitions The definition of personal property includes but it not limited to the following. Accountability - A property management function that involves maintaining an account or record of personal property and personal property transactions from receipt to final disposition. *Accountable Personal Property - Nonexpendable personal property with an acquisition cost of $5,000 or greater, DOE-leased personal

  6. Communication methods, systems, apparatus, and devices involving RF tag registration

    DOE Patents [OSTI]

    Burghard, Brion J.; Skorpik, James R.

    2008-04-22

    One technique of the present invention includes a number of Radio Frequency (RF) tags that each have a different identifier. Information is broadcast to the tags from an RF tag interrogator. This information corresponds to a maximum quantity of tag response time slots that are available. This maximum quantity may be less than the total number of tags. The tags each select one of the time slots as a function of the information and a random number provided by each respective tag. The different identifiers are transmitted to the interrogator from at least a subset of the RF tags.

  7. Probative Investigation of the Thermal Stability of Wastes Involved...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    This document corresponds to Appendix FG: Reaction Chemistry & HypothesisSummary of Reactivity Testing of the Technical Assessment Team Report. PDF icon Probative Investigation ...

  8. Two concurrent EIS projects involving the same agencies

    SciTech Connect (OSTI)

    Thompson, M.G. ); Schaddel, T.L. . Div. of Aeronautics)

    1993-01-01

    In 1990-91 the US Air Force prepared environmental impact statements (EIS) for the disposal and reuse of Chanute Air Force Base in Rantoul, Illinois and for the joint military-civilian use of Scott Air Force Base in St. Clair County, Illinois. The Federal Aviation Administration, Chicago Airports District Office and the Illinois Department of Transportation, Division of Aeronautics were cooperating agencies for both projects. This paper summarizes the two environmental impact statements and analyzes the processes followed in preparing both documents.

  9. Definite Integrals, Some Involving Residue Theory Evaluated by Maple Code

    SciTech Connect (OSTI)

    Bowman, Kimiko o [ORNL

    2010-01-01

    The calculus of residue is applied to evaluate certain integrals in the range (-{infinity} to {infinity}) using the Maple symbolic code. These integrals are of the form {integral}{sub -{infinity}}{sup {infinity}} cos(x)/[(x{sup 2} + a{sup 2})(x{sup 2} + b{sup 2}) (x{sup 2} + c{sup 2})]dx and similar extensions. The Maple code is also applied to expressions in maximum likelihood estimator moments when sampling from the negative binomial distribution. In general the Maple code approach to the integrals gives correct answers to specified decimal places, but the symbolic result may be extremely long and complex.

  10. Tri-Party Agreement Agencies - Public involvement calendar -...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ...vironmentalAssessments Draft Natural Gas Pipeline and Natural Gas Utility Service ...EnvironmentalImpactStatements Class 3 permit modification to put all SWOC units final ...

  11. Multidomain Carbohydrate-binding Proteins Involved in Bacteroides...

    Office of Scientific and Technical Information (OSTI)

    Starch Metabolism Authors: Cameron, Elizabeth A. ; Maynard, Mallory A. ; Smith, Christopher J. ; Smith, Thomas J. ; Koropatkin, Nicole M. ; Martens, Eric C. 1 ; Danforth) 2 + ...

  12. Weak interaction processes in nuclei involving neutrinos and CDM candidates

    SciTech Connect (OSTI)

    Kosmas, T. S.; Tsakstara, V. [Theoretical Physics Section, University of Ioannina, GR 45110 Ioannina (Greece); Divari, P. C. [Department of Physical Sciences, Hellenic Army Academy, Vari 16673, Attica (Greece); Sinatkas, J. [Department of Informatics and Computer Technology, TEI of Western Macedonia, GR-52100 Kastoria (Greece)

    2009-11-09

    In this work, we concentrate on the nuclear physics aspects of low-energy neutrinos and in particular on problems related to neutrino detection by terrestrial experiments, neutrino astrophysics and neutrino-nucleus interactions. The detection of low-flux neutrinos, feasible by measuring the energy recoil of the recoiling nucleus with gaseous-detectors having very-low threshold-energy, is carried out in conjunction with direct-detection of cold dark matter events and nonstandard physics searches like the neutrinoless double beta decay.

  13. TRI-PARTY AGREEMENT HANFORD PUBLIC INVOLVEMENT PLAN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... of comments is provided in bold italicized text. ... Seattle high school students knowledgeable about ... The U.S. Department of Energy (DOE) and the Washington State ...

  14. Consistent analysis of one-nucleon spectroscopic factors involving...

    Office of Scientific and Technical Information (OSTI)

    Additional Journal Information: Journal Name: Physics Letters. Section B; Journal ID: ISSN 0370-2693 Publisher: Elsevier Sponsoring Org: USDOE Country of Publication: Netherlands ...

  15. Overview of Processes Involved in Spin Transfer Collisions

    SciTech Connect (OSTI)

    Buttimore, N. H.

    2008-04-30

    An outline is provided of methods for polarizing antiprotons that include the possible use of channelling in a bent crystal and also the technique of scattering off leptons or protons at a suitably small angle. In the method of channelling it is suggested that the angular dependence of the analysing power of the incident particle is cubic in the angle for single scattering in the crystal when this takes place within the region of electromagnetic hadronic interference as is most likely for channelled particles. Polarization transfer in the scattering of antiprotons off leptons or protons is discussed in addition where emphasis is laid on the angular integrals over spin observables appropriate for spin filtering.

  16. Metaproteomics Identifies the Protein Machinery Involved in Metal...

    Office of Scientific and Technical Information (OSTI)

    This research effort integrated current understanding of the microbiology and biochemistry of U(VI) reduction and capitalize on advances in proteomics technology made over the past ...

  17. OpenEI:Get Involved | Open Energy Information

    Open Energy Info (EERE)

    and contribute to OpenEI. Sign up for an account then start contributing wiki content Use social media to help share the word about OpenEI Join a local energy or technology...

  18. RAPID/Best Practices/Public Involvement | Open Energy Information

    Open Energy Info (EERE)

    - use a broad range of communication tools, including public meetings, a project website, social media accounts, press releases, advertisements in local newspapers and...

  19. Biochemical localization of a protein involved in Gluconacetobacter...

    Office of Scientific and Technical Information (OSTI)

    States Language: English Subject: 59 BASIC BIOLOGICAL SCIENCES biofuels (including algae and biomass), bio-inspired, membrane, carbon sequestration, materials and chemistry by...

  20. Metaproteomics Identifies the Protein Machinery Involved in Metal...

    Office of Scientific and Technical Information (OSTI)

    mining, controlled laboratory studies, U(VI) reduction activity measurements, phylogenetic analyses, and gene expression studies to support the metaproteomics characterizations. ...

  1. Creating an Ethical Framework for Studies That Involve the Worker...

    Office of Science (SC) Website

    ... K - Bibliography and Resources .pdf file (26KB) References used in this document are listed and identified, and a list of Internet Web site addresses is also provided. L - ...

  2. Processing and analysis techniques involving in-vessel material generation

    DOE Patents [OSTI]

    Schabron, John F.; Rovani, Jr., Joseph F.

    2011-01-25

    In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the solution of interest may include dissolution of the material, perhaps as part of a successive dissolution protocol using solvents of increasing ability to dissolve. Applications include, but are by no means limited to estimation of a coking onset and solution (e.g., oil) fractionating.

  3. Processing and analysis techniques involving in-vessel material generation

    DOE Patents [OSTI]

    Schabron, John F.; Rovani, Jr., Joseph F.

    2012-09-25

    In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the solution of interest may include dissolution of the material, perhaps as part of a successive dissolution protocol using solvents of increasing ability to dissolve. Applications include, but are by no means limited to estimation of a coking onset and solution (e.g., oil) fractionating.

  4. Worker Involvement Improves Safety at Hanford Site's Plutonium Finishing Plant

    Broader source: Energy.gov [DOE]

    Employees at the Hanford site are working together to find new and innovative ways to stay safe at the Plutonium Finishing Plant, one of the site’s most complex decommissioning projects.

  5. Mutation assays involving blood cells that metabolize toxic substances

    DOE Patents [OSTI]

    Crespi, Charles L.; Thilly, William G.

    1999-01-01

    The present invention pertains to a line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity). Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. The invention also includes mutation assays using these cells, and other cells with similar characteristics.

  6. Mutation assays involving blood cells that metabolize toxic substances

    DOE Patents [OSTI]

    Crespi, Charles L.; Thilly, William G.

    1985-01-01

    A line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity) is disclosed. Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. Mutation assays using these cells, and other cells with similar characteristics, are also disclosed.

  7. Mutation assays involving blood cells that metabolize toxic substances

    DOE Patents [OSTI]

    Crespi, C.L.; Thilly, W.G.

    1999-08-10

    The present invention pertains to a line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity). Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. The invention also includes mutation assays using these cells, and other cells with similar characteristics. 3 figs.

  8. Kinetics and mechanisms of reactions involving small aromatic reactive intermediates

    SciTech Connect (OSTI)

    Lin, M.C.

    1993-12-01

    Small aromatic radicals such as C{sub 6}H{sub 5}, C{sub 6}H{sub 5}O and C{sub 6}H{sub 4} are key prototype species of their homologs. C{sub 6}H{sub 5} and its oxidation product, C{sub 6}H{sub 5}O are believed to be important intermediates which play a pivotal role in hydrocarbon combustion, particularly with regard to soot formation. Despite their fundamental importance, experimental data on the reaction mechanisms and reactivities of these species are very limited. For C{sub 6}H{sub 5}, most kinetic data except its reactions with NO and NO{sub 2}, were obtained by relative rate measurements. For C{sub 6}H{sub 5}O, the authors have earlier measured its fragmentation reaction producing C{sub 5}H{sub 5} + CO in shock waves. For C{sub 6}H{sub 4}, the only rate constant measured in the gas phase is its recombination rate at room temperature. The authors have proposed to investigate systematically the kinetics and mechanisms of this important class of molecules using two parallel laser diagnostic techniques--laser resonance absorption (LRA) and resonance enhanced multiphoton ionization mass spectrometry (REMPI/MS). In the past two years, study has been focused on the development of a new multipass adsorption technique--the {open_quotes}cavity-ring-down{close_quotes} technique for kinetic applications. The preliminary results of this study appear to be quite good and the sensitivity of the technique is at least comparable to that of the laser-induced fluorescence method.

  9. Public Involvement in the Environmental Assessment Process (DOE, 2010)

    Broader source: Energy.gov [DOE]

    A DOE policy regarding the online publication and electronic notification of the availability of draft environmental assessments (EAs) for public comment.

  10. CHL1 is involved in human breast tumorigenesis and progression

    SciTech Connect (OSTI)

    He, Li-Hong; Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin ; Ma, Qin; Shi, Ye-Hui; Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin ; Ge, Jie; Zhao, Hong-Meng; Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin ; Li, Shu-Fen; Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin ; Tong, Zhong-Sheng; Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin

    2013-08-23

    Highlights: CHL1 is down-regulation in breast cancer tissues. Down-regulation of CHL1 is related to high grade. Overexpression of CHL1 inhibits breast cancer cell proliferation and invasion in vitro. CHL1 deficiency induces breast cancer cell proliferation and invasion both in vitro and in vivo. -- Abstract: Neural cell adhesion molecules (CAM) play important roles in the development and regeneration of the nervous system. The L1 family of CAMs is comprised of L1, Close Homolog of L1 (CHL1, L1CAM2), NrCAM, and Neurofascin, which are structurally related trans-membrane proteins in vertebrates. Although the L1CAM has been demonstrated play important role in carcinogenesis and progression, the function of CHL1 in human breast cancer is limited. Here, we found that CHL1 is down-regulated in human breast cancer and related to lower grade. Furthermore, overexpression of CHL1 suppresses proliferation and invasion in MDA-MB-231 cells and knockdown of CHL1 expression results in increased proliferation and invasion in MCF7 cells in vitro. Finally, CHL1 deficiency promotes tumor formation in vivo. Our results may provide a strategy for blocking breast carcinogenesis and progression.

  11. The research performed during the last granting period involved...

    Office of Scientific and Technical Information (OSTI)

    Current Genetics. 55, 273-286. Some of the following papers were listed as "submitted" in the previous renewal: Our major findings are on the last paper which we are still revising ...

  12. Fukushima Media Involvement: Lessons Learned and Challenges - 13261

    SciTech Connect (OSTI)

    Harvey, Geoffrey L.; Johnson, Wayne L.; Koller, Greg L.

    2013-07-01

    Only days after the Fukushima nuclear reactor disaster on March 11, 2011, the DOE's Pacific Northwest National Laboratory, or PNNL, found itself in a maelstrom of media attention following its announcement of the detection of minute levels of radioactive material originating from the damaged reactors 4,500 miles away. Because PNNL develops state-of-the-art ultra-sensitive radionuclide detection and monitoring systems for national security applications, and has some of the equipment operating on its Richland campus, there was little surprise when one of these sophisticated systems led PNNL to be the first to detect measurable radionuclides in the United States. On Wednesday, March 16, 2011, that system detected minuscule levels of short-lived radioactive xenon, a telltale element derived from either weapons testing or a major reactor disruption. Immediately after the detection was announced, a flurry of inquiries nearly overwhelmed staff as governments, scientific organizations, the general public, and reporters struggled to understand and estimate what impacts this disaster might have on health and environment. Over the course of about three weeks, PNNL's News and Media Relations staff and its scientists and engineers responded to more than 100 requests for information, and engaged in dozens of personal interviews with international, national, regional, and local media. While many of the interviews and resulting stories were accurate and well done, not all communication went flawlessly. In the midst of chaos and confusion, which are part of any significant crisis, hiccoughs are sure to occur. Addressed here is 'the rest of the story'. (authors)

  13. N"I. L-S- Rad. Mat. DU

    Office of Legacy Management (LM)

    GROSS SUMMARY OF INFORMATION FROM NUCLEAR MATERIAL TRANSACTION REPORTS (DOENRC ... government-owned material. 31 The Nuclear Material Transaction Reports from 1958 ...

  14. SC e-journals, Mathematics

    Office of Scientific and Technical Information (OSTI)

    Video Technology, IEEE Transactions on Circuits and Systems Part I: Fundamental Theory and Applications, IEEE Transactions on Circuits and Systems Part II: Analog and Digital ...

  15. SC e-journals, Computer Science

    Office of Scientific and Technical Information (OSTI)

    Video Technology, IEEE Transactions on Circuits and Systems Part I: Fundamental Theory and Applications, IEEE Transactions on Circuits and Systems Part II: Analog and Digital ...

  16. Infrastructure Development - Building America Top Innovations...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    influenced codes and standards and improvements in education and the transaction process. ... Recognizing Value in Transaction Process 2014 Top Innovation Valuing Green in the ...

  17. Plains and Eastern Clean Line

    Broader source: Energy.gov (indexed) [DOE]

    ... Vinson & Elkins - Attorney Represented clients in merger and acquisition, project development and private equity investment transactions, including transactions in the wind ...

  18. U.S. Residential Photovoltaic (PV) System Prices, Q4 2013 Benchmarks: Cash Purchase, Fair Market Value, and Prepaid Lease Transaction Prices

    SciTech Connect (OSTI)

    Davidson, C.; James, T. L.; Margolis, R.; Fu, R.; Feldman, D.

    2014-10-01

    The price of photovoltaic (PV) systems in the United States (i.e., the cost to the system owner) has dropped precipitously in recent years, led by substantial reductions in global PV module prices. This report provides a Q4 2013 update for residential PV systems, based on an objective methodology that closely approximates the book value of a PV system. Several cases are benchmarked to represent common variation in business models, labor rates, and module choice. We estimate a weighted-average cash purchase price of $3.29/W for modeled standard-efficiency, polycrystalline-silicon residential PV systems installed in the United States. This is a 46% decline from the 2013-dollar-adjusted price reported in the Q4 2010 benchmark report. In addition, this report frames the cash purchase price in the context of key price metrics relevant to the continually evolving landscape of third-party-owned PV systems by benchmarking the minimum sustainable lease price and the fair market value of residential PV systems.

  19. Transactions of the twenty-third water reactor safety information meeting to be held at Bethesda Marriott Hotel, Bethesda, Maryland, October 23--25, 1995

    SciTech Connect (OSTI)

    Monteleone, S.

    1995-09-01

    This report contains summaries of papers on reactor safety research to be presented at the 23rd Water Reactor Safety Information Meeting at the Bethesda Marriott Hotel, Bethesda, Maryland, October 23--25, 1995. The summaries briefly describe the programs and results of nuclear safety research sponsored by the Office of Nuclear Regulatory, Research, US NRC. Summaries of invited papers concerning nuclear safety issues from US government laboratories, the electric utilities, the nuclear industry, and from foreign governments and industry are also included. The summaries have been compiled in one report to provide a basis for meaningful discussion and information exchange during the course of the meeting and are given in the order of their presentation in each session.

  20. International energy agency

    SciTech Connect (OSTI)

    Not Available

    1988-01-01

    The International Energy Agency's emergency oil sharing system is designed to enable member nations to share oil supplied during an oil supply disruption equal to or exceeding 7 percent or more of members' oil supplies. However, participation could have anticompetitive consequences and under U.S. antitrust laws could result in suits against U.S. companies. To ensure participation of major U.S. oil companies, legislation provides a statutory defense against any civil or criminal suit brought under federal or state antitrust laws for some actions. This report describes efforts to expand the antitrust and breach of contract defenses for oil company supply transactions during an oil emergency and to resolve the problem of foreign blockage of information critical to U.S. antitrust review of oil transactions involving foreign affiliates of U.S. companies.

  1. International Energy Agency

    SciTech Connect (OSTI)

    Not Available

    1988-03-01

    The International Energy Agency's emergency oil sharing system is designed to enable member nations to share oil supplies during an oil supply disruption equal to or exceeding 7 percent or more of members' oil supplies. However, participation could have anticompetitive consequences and under U.S. antitrust laws could result in suits against U.S. companies. To ensure participation of major U.S. oil companies, legislation provides a statutory defense against any civil or criminal suit brought under federal or state antitrust laws for some actions. This report describes efforts to expand the antitrust and breach of contract defenses for oil company supply transactions during an oil emergency and to resolve the problem of foreign blockage of information critical to U.S. antitrust review of oil transactions involving foreign affilitates of U.S. companies.

  2. Electric trade in the United States 1992

    SciTech Connect (OSTI)

    Not Available

    1994-09-01

    This publication, Electric Trade in the US 1992 (ELECTRA), is the fourth in a series of reports on wholesale power transactions prepared by the Electric Data Systems Branch, Survey Management Division, Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA). The electric trade data are published biennially. The first report presented 1986 data, and this report provides information on the electric power industry during 1992. The electric trade data collected and presented in this report furnish important information on the wholesale structure found within the US electric power industry. The patterns of interutility trade in the report support analyses of wholesale power transactions and provide input for a broader understanding of bulk power market issues that define the emerging national electric energy policies. The report includes information on the quantity of power purchased, sold, exchanged, and wheeled; the geographical locations of transactions and ownership classes involved; and the revenues and costs. Information on the physical transmission system are being included for the first time in this publication. Transmission data covering investor-owned electric utilities were shifted from the Financial Statistics of Selected Investor-Owned Electric Utilities to the ELECTRA publication. Some of the prominent features of this year`s report include information and data not published before on transmission lines for publicly owned utilities and transmission lines added during 1992 by investor-owned electric utilities.

  3. Technology Deployment Annual Report 2010

    SciTech Connect (OSTI)

    Keith Arterburn

    2010-12-01

    This report is a catalog of selected INL technology transfer and commercialization transactions during FY-2010.

  4. Acquisition Guide Chapter 17.1 - Interagency Acquisitions, Interagency

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transactions, and Interagency Agreements | Department of Energy 1 - Interagency Acquisitions, Interagency Transactions, and Interagency Agreements Acquisition Guide Chapter 17.1 - Interagency Acquisitions, Interagency Transactions, and Interagency Agreements Acquisition Guide Chapter 17.1 - Interagency Acquisitions, Interagency transactions, and Interagency Agreements is revised to incorporate (1) Federal Acquisition Circular (FAC) changes to Federal Acquisition Regulation (FAR) Part 17.5 -

  5. Solar Utility Procurement Specialist

    Broader source: Energy.gov [DOE]

    Alternate Title(s):Renewable Energy Procurement Associate; Renewable Energy Transactions Specialist;

  6. Tag: UPF | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    UPF Tag: UPF Displaying 1 - 10 of 14... Category: About UPF Forecast UPF Procurement provides the following forecast of subcontracting opportunities. More... Category: News UPF site readiness subproject completed on time and under budget The UPF project celebrates its first major milestone with the completion of site readiness work, delivered on time and under budget. More... Category: About Bartering results in cost savings Borrowing UCOR's government-furnished equipment eliminated some

  7. Report to Congress on the Small Business Program

    SciTech Connect (OSTI)

    Not Available

    1989-01-01

    The Department of Energy's (DOE) Small Business Program is characterized by its diligent involvement in the procurement process to enhance participation by small businesses, small disadvantaged businesses, labor surplus area firms, and women-owned businesses. The DOE's primary means of securing an equitable proportion of transactions for these businesses are total set-asides, partial set-asides, 8(a) sole source procurements, and 8(a) competitive procurements. Throughout the DOE's infrastructure, all DOE organizational elements are committed to successfully implement the Small Business Program. The Department's commitment includes developing substantial opportunities in both prime contracting and subcontracting and encompasses special preference programs to enhance awards to such businesses.

  8. Pitfalls of preparing deeds conveying oil and gas interests

    SciTech Connect (OSTI)

    Hawkins, E.G.

    1986-01-01

    A sudden increase in legal activity involving the preparation or review of deeds to oil and gas interests is the result of expanded exploration and development activities in Alabama. Because of the complexities of an oil or gas transaction and the presence of title defects, there are legal problems which are unique to these cases. The author highlights some of the more common problems and defects, and recommends ways for lawyers to avoid them. The discussion touches on the mineral deed versus the royalty deed, conflicts over the mineral acre versus the fractional grant, the rule against perpetuities, roadways, and other problems.

  9. Operation of Distributed Generation Under Stochastic Prices

    SciTech Connect (OSTI)

    Siddiqui, Afzal S.; Marnay, Chris

    2005-11-30

    We model the operating decisions of a commercial enterprisethatneeds to satisfy its periodic electricity demand with either on-sitedistributed generation (DG) or purchases from the wholesale market. Whilethe former option involves electricity generation at relatively high andpossibly stochastic costs from a set of capacity-constrained DGtechnologies, the latter implies unlimited open-market transactions atstochastic prices. A stochastic dynamic programme (SDP) is used to solvethe resulting optimisation problem. By solving the SDP with and withoutthe availability of DG units, the implied option values of the DG unitsare obtained.

  10. Slide04 | OSTI, US Dept of Energy, Office of Scientific and Technical

    Office of Scientific and Technical Information (OSTI)

    Information Web Traffic OSTI information transactions have increased from 2 million to 250 million. Information Transactions: discrete information exchanges between a user and an OSTI web product.

  11. Sensors and Controls R&D

    Broader source: Energy.gov [DOE]

    The Transactional Network enables energy, operational, and financial transactions between networked building systems (like rooftop units) and the electric power grid using software applications on the platform or in the Cloud.

  12. Lessons from the new institutional economics

    SciTech Connect (OSTI)

    Olson, W.P.

    1997-06-01

    Policy makers should seek to get the structure right ex ante as antitrust may not be effective ex post. It will be important to deal effectively with information asymmetries and to minimize transaction costs. The electric services industry is experiencing a period of rapid change, entrepreneurship, innovation and increased competition. The introduction of direct-access retail competition, for example, is becoming increasingly feasible because of the path-breaking activities of England, Norway, Chile and California. While the basic model of a reformed electric services industry has begun to come into a sharper focus, the techniques and methods that policy makers and regulators will need to use in evaluating electric restructuring plans are less well understood. If regulators and their staffs only use the traditional analytical tools, they could fail to analyze fully the transaction cost implications of alternative market, industry and corporate structures. An appreciation of the implications of the new institutional economics (NIE), of which transaction cost economics (TCE) is an important subset, can provide valuable insights. The new institutional economics: (1) holds that institutions matter and are susceptible to analysis..., (2) is different from but not hostile to orthodoxy, and (3) is an interdisciplinary combination of law, economics, and organization in which economics is the first among equals. This paper surveys several of the analytical tools of the new institutional economics, with an emphasis on the tools that are most relevant to the design of the market, industry and corporate structure of a restructured electric services industry. This article applies ME and TCE tools but does not attempt to provide a comprehensive survey of the issues involved in electric restructuring. Rather, it illustrates how regulators can use the tools of NIE/TCE to evaluate and solve the difficult practical problems that electric restructuring presents.

  13. Technology Transfer and Commercialization Annual Report 2008

    SciTech Connect (OSTI)

    Michelle R. Blacker

    2008-12-01

    The Idaho National Laboratory (INL) is a Department of Energy (DOE) multi-program national laboratory that conducts research and development in all DOE mission areas. Like all other federal laboratories, INL has a statutory, technology transfer mission to make its capabilities and technologies available to all federal agencies, to state and local governments, and to universities and industry. To fulfill this mission, INL encourages its scientific, engineering, and technical staff to disclose new inventions and creations to ensure the resulting intellectual property is captured, protected, and made available to others who might benefit from it. As part of the mission, intellectual property is licensed to industrial partners for commercialization, creating jobs and delivering the benefits of federally funded technology to consumers. In other cases, unique capabilities are made available to other federal agencies or to regional small businesses to solve specific technical challenges. In other interactions, INL employees work cooperatively with researchers and other technical staff of our partners to further develop emerging technologies. This report is a catalog of selected INL technology transfer and commercialization transactions during this past year. The size and diversity of INL technical resources, coupled with the large number of relationships with other organizations, virtually ensures that a report of this nature will fail to capture all interactions. Recognizing this limitation, this report focuses on transactions that are specifically authorized by technology transfer legislation (and corresponding contractual provisions) or involve the transfer of legal rights to technology to other parties. This report was compiled from primary records, which were readily available to the INL’s Office of Technology Transfer & Commercialization. The accomplishments cataloged in the report, however, reflect the achievements and creativity of the highly skilled researchers, technicians, support staff, and operators of the INL workforce. Their achievements and recognized capabilities are what make the accomplishments cataloged here possible. Without them, none of these transactions would occur.

  14. Toda Material/Component Production Facilities

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    billion transaction global diversified trading company * Focused growth strategy ... management and partnerships, finance, trading and sales * Complementary to Toda's ...

  15. U

    National Nuclear Security Administration (NNSA)

    4 SPONSORED BY DOE AND NRC PREPARED BY NAC INTERNATIONAL Reporting Export and Import Reporting Export and Import Reporting Export and Import Reporting Export and Import Transaction Data to NMMSS Transaction Data to NMMSS Transaction Data to NMMSS Transaction Data to NMMSS During the 2004 NMMSS Users Annual Training Meeting, several questions were asked concerning the requirements for reporting the export and imports of nuclear materials to NMMSS. Following is some basic information and

  16. Sintering Kinetics of Inkjet Printed Conductive Silver Lines...

    Office of Scientific and Technical Information (OSTI)

    Journal Name: Metallurgical and Materials Transactions. B, ... Publisher: ASM International Research Org: Oak Ridge ... Deposition Modeling; Electrical Properties Word Cloud ...

  17. Transfer reactions at ATLAS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Services » Transactions, Technology and Contractor Human Relations Transactions, Technology and Contractor Human Relations Transactions, Technology and Contractor Human Relations Offices of the Deputy General Counsel for Transactions, Technology and Contractor Human Resources Office of the Assistant General Counsel for Procurement and Financial Assistance (GC-61) Office of the Assistant General Counsel for Technology Transfer and Intellectual Property (GC-62) Office of the Assistant

  18. Intellectual Property (IP) Service Providers for Acquisition...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Intellectual Property Provides ACQ and Assistance More Documents & Publications Intellectual Property (IP) Service Providers for Acquisition and Assistance Transactions Microsoft ...

  19. Intellectual Property (IP) Service Providers for Acquisition...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DOEIPCounselforDOELaboratories 2015 More Documents & Publications Intellectual Property (IP) Service Providers for Acquisition and Assistance Transactions ...

  20. Scalability Analysis of Volttron Platform

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Presented at: Technical Meeting on Software Framework for Transactive Energy: ... to Scalable Applications Control software Virtual interface Virtual environment ...

  1. Acquisition Guide Chapter 71.1 - Headquarters Business Clearance...

    Broader source: Energy.gov (indexed) [DOE]

    In accomplishing its mission, the FAOD reviews acquisition plans, solicitations, source selection documents, contracts, and other relevant transactional documentation....

  2. Funding Opportunity Announcement: Solar Bankability Data to Advance

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transactions and Access (SB-DATA) | Department of Energy Funding Opportunity Announcement: Solar Bankability Data to Advance Transactions and Access (SB-DATA) Funding Opportunity Announcement: Solar Bankability Data to Advance Transactions and Access (SB-DATA) Funding Number: DE-FOA-0001319 Funding Amount: $5,000,000 Description The Solar Bankability Data to Advance Transactions and Access (SB-DATA) funding program targets soft cost reduction by increasing data accessibility and quality. It

  3. SC e-journals, Earth Sciences

    Office of Scientific and Technical Information (OSTI)

    Facilities Environmental Journal Frontiers in Ecology and the Environment Geobiology Geo-Marine Letters Geochemical Transactions - OAJ Geochemistry, Geophysics, Geosystems ...

  4. Biographical sketch - Anne Jones | Center for Bio-Inspired Solar...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Inorganic Chemistry, Chemical Reviews, Dalton Transactions, Physical Chemistry Chemical Physics, Electrochemistry Communications, Journal of Electroanalytical Chemistry...

  5. Emergence of Natural Gas Market Centers

    Reports and Publications (EIA)

    1996-01-01

    Discusses the value of market centers in today's marketplace, highlighting their importance in capacity and financial transactions.

  6. Sensors and Controls Reports

    Broader source: Energy.gov [DOE]

    Reports from the sensors, controls, and transactional network program. The transactional network is between appliances, buildings, and utilities, and can enable Smart Buildings -- buildings with technologies and control systems that can not only optimize energy performance and comfort, but also support energy-related transactions outside the building envelope.

  7. Energy conversion system involving change in the density of an upwardly moving liquid

    DOE Patents [OSTI]

    Petrick, Michael (Jolliet, IL)

    1989-01-01

    A system for converting thermal energy into electrical energy includes a fluid reservoir, a relatively high boiling point fluid such as lead or a lead alloy within the reservoir, a downcomer defining a vertical fluid flow path communicating at its upper end with the reservoir and an upcomer defining a further vertical fluid flow path communicating at its upper end with the reservoir. A variable area nozzle of rectangular section may terminate the upper end of the upcomer and the lower end of the of the downcomer communicates with the lower end of the upcomer. A mixing chamber is located at the lower end portion of the upcomer and receives a second relatively low boiling point fluid such as air, the mixing chamber serving to introduce the low boiling point fluid into the upcomer so as to produce bubbles causing the resultant two-phase fluid to move at high velocity up the upcomer. Means are provided for introducing heat into the system preferably between the lower end of the downcomer and the lower end of the upcomer. Power generating means are associated with the one of the vertical fluid flow paths one such power generating means being a magneto hydrodynamic electrical generator.

  8. Phi ({Phi}) and psi ({Psi}) angles involved in malarial peptide bonds determine sterile protective immunity

    SciTech Connect (OSTI)

    Patarroyo, Manuel E.; Moreno-Vranich, Armando; Bermudez, Adriana

    2012-12-07

    Highlights: Black-Right-Pointing-Pointer Phi ({Phi}) and psi ({Psi}) angles determine sterile protective immunity. Black-Right-Pointing-Pointer Modified peptide's tendency to assume a regular conformation related to a PPII{sub L}. Black-Right-Pointing-Pointer Structural modifications in mHABPs induce Ab and protective immunity. Black-Right-Pointing-Pointer mHABP backbone atom's interaction with HLA-DR{beta}1{sup Asterisk-Operator} is stabilised by H-bonds. -- Abstract: Modified HABP (mHABP) regions interacting with HLA-DR{beta}1{sup Asterisk-Operator} molecules have a more restricted conformation and/or sequence than other mHABPs which do not fit perfectly into their peptide binding regions (PBR) and do not induce an acceptable immune response due to the critical role of their {Phi} and {Psi} torsion angles. These angle's critical role was determined in such highly immunogenic, protection-inducing response against experimental malaria using the conformers (mHABPs) obtained by {sup 1}H-NMR and superimposed into HLA-DR{beta}1{sup Asterisk-Operator }-like Aotus monkey molecules; their phi ({Phi}) and psi ({Psi}) angles were measured and the H-bond formation between these molecules was evaluated. The aforementioned mHABP propensity to assume a regular conformation similar to a left-handed polyproline type II helix (PPII{sub L}) led to suggesting that favouring these conformations according to their amino acid sequence would lead to high antibody titre production and sterile protective immunity induction against malaria, thereby adding new principles or rules for vaccine development, malaria being one of them.

  9. Thermal reactive ion etching technique involving use of self-heated cathode

    SciTech Connect (OSTI)

    Yamada, S.; Minami, Y.; Sohgawa, M.; Abe, T.

    2015-04-15

    In this work, the thermal reactive ion etching (TRIE) technique for etching hard-to-etch materials is presented. The TRIE technique employs a self-heated cathode and a thermally insulated aluminum plate is placed on the cathode of a regular reactive ion etching (RIE) system. By optimizing the beam size to support the sample stage, the temperature of the stage can be increased to a desired temperature without a cathode heater. The technique was used to etch a bulk titanium plate. An etch rate of 0.6 μm/min and an etch selectivity to nickel of 100 were achieved with SF{sub 6} plasma. The proposed technique makes a regular RIE system a more powerful etcher without the use of chlorine gas, a cathode heater, and an inductively coupled plasma source.

  10. Heat flux expressions that satisfy the conservation laws in atomistic system involving multibody potentials

    SciTech Connect (OSTI)

    Fu, Yao Song, Jeong-Hoon

    2015-08-01

    Heat flux expressions are derived for multibody potential systems by extending the original Hardy's methodology and modifying Admal & Tadmor's formulas. The continuum thermomechanical quantities obtained from these two approaches are easy to compute from molecular dynamics (MD) results, and have been tested for a constant heat flux model in two distinctive systems: crystalline iron and polyethylene (PE) polymer. The convergence criteria and affecting parameters, i.e. spatial and temporal window size, and specific forms of localization function are found to be different between the two systems. The conservation of mass, momentum, and energy are discussed and validated within this atomistic–continuum bridging.

  11. Investigations of the Fundamental Surface Reactions Involved in the Sorption and Desorption of Radionuclides

    SciTech Connect (OSTI)

    Czerwinski, Ken; Heske, Clemens; Moser, Duane; Misra, Mnoranjan; McMillion, Glen

    2011-04-20

    Models for describing solution- and surface-phase reactions have been used for 30 years, but only recently applicable to complex surfaces. Duff et al., using micro-XANES, found that Pu was concentrated on Mn-oxide and smectite phases of zeolitic tuff, providing an evaluation of contaminant speciation on surfaces for modeling. Experiments at Los Alamos demonstrated that actinides display varying surface residence time distributions, probably reflective of mineral surface heterogeneity. We propose to investigate the sorption/desorption behavior of radionuclides from mineral surfaces, as effected by microorganisms, employing isolates from Nevada Test Site deep alluvium as a model system. Characterizations will include surface area, particle size distribution, x-ray diffraction (XRD), microprobe analysis, extractions, and microbiology. Surface interactions will be assessed by electron spectroscopy (XPS), x-ray absorption fine structure spectroscopy (XAFS), X-ray emission spectroscopy, transmission electron microscopy (TEM) and Scanning electron microscopy (SEM). Desert Research Institute (DRI), University of Nevada, Reno (UNR), and University of Nevada, Las Vegas (UNLV) researchers will collaborate to enhance scientific infrastructure and the understanding of contaminant behavior on surfaces, with broader implications for the management of DOE sites.

  12. Search for doubly charged Higgs bosons with lepton-flavour-violating decays involving tau leptons

    SciTech Connect (OSTI)

    Aaltonen, T.

    2007-12-01

    The authors search for pair production of doubly charged Higgs particles (H{sup {+-}{+-}}) followed by decays into electron-tau (e{tau}) and muon-tau ({mu}{tau}) pairs using a data set corresponding to an integrated luminosity of 350 pb{sup -1} collected from {bar p}p collisions at {radical}s = 1.96 TeV by the CDF II experiment. They search separately for cases where three or four final-state leptons are detected, and then combine the results into limits for each exclusive flavor decay mode of the H{sup {+-}{+-}}. Assuming 100% branching ratios of the H{sup {+-}{+-}} to left-handed e{tau} ({mu}{tau}) pairs, they set an H{sup {+-}{+-}} lower mass limit of 114 (112) GeV/c{sup 2} at the 95% confidence level (C.L.).

  13. Laser-driven deflection arrangements and methods involving charged particle beams

    DOE Patents [OSTI]

    Plettner, Tomas; Byer, Robert L.

    2011-08-09

    Systems, methods, devices and apparatus are implemented for producing controllable charged particle beams. In one implementation, an apparatus provides a deflection force to a charged particle beam. A source produces an electromagnetic wave. A structure, that is substantially transparent to the electromagnetic wave, includes a physical structure having a repeating pattern with a period L and a tilted angle .alpha., relative to a direction of travel of the charged particle beam, the pattern affects the force of the electromagnetic wave upon the charged particle beam. A direction device introduces the electromagnetic wave to the structure to provide a phase-synchronous deflection force to the charged particle beam.

  14. The Bond Between CO and Cp?3U in Cp?3U(CO) involves Backbondingfrom...

    Office of Scientific and Technical Information (OSTI)

    The origin of the large difference between the stretching frequencies in free (2143 cm-1) ... Subject: 37; ADDUCTS; BONDING; ELECTRONS; ORIGIN; URANIUM uranium orbitals backbonding ...

  15. Systematic identification of genes and transduction pathways involved in radio-adaptive response

    SciTech Connect (OSTI)

    Wu, Honglu

    2015-05-22

    Low doses of radiation have been shown to protect against the biological effects of later exposure to toxic levels of radiation. In this study, we propose to identify the molecular mechanisms of this adaptive response by systematically identifying the genes that play a role in radio-protection. In the original proposal, a human cell line that is well-documented to exhibit the radio-adaptive effect was to be used. In this revised study plan, we will use a mouse model, C57BL/6, which has also been well investigated for radio-adaptation. The goal of the proposed study is to enhance our understanding of cellular responses to low doses of radiation exposure at the molecular level.

  16. Compositions and methods involving methyladenosine phosphorylase in the diagnosis and treatment of proliferative disorders

    DOE Patents [OSTI]

    Olopade, Olufunmilayo I.

    2007-03-20

    Disclosed are novel nucleic acid and peptide compositions comprising methylthioadenosine phosphorylase (MTAP) and methods of use for MTAP amino acid sequences and DNA segments comprising MTAP in the diagnosis of human cancers and development of MTAP-specific antibodies. Also disclosed are methods for the diagnosis and treatment of tumors and other proliferative cell disorders, and identification of tumor suppressor genes and gene products from the human 9p21-p22 chromosome region. Such methods are useful in the diagnosis of multiple tumor types such as bladder cancer, lung cancer, breast cancer, pancreatic cancer, brain tumors, lymphomas, gliomas, melanomas, and leukemias.

  17. Effect of hydrotropic salts on phase relationships involving hydrocarbons, water, and alcohols

    SciTech Connect (OSTI)

    Ho, P.C.; Kraus, K.A.

    1980-01-01

    Hydrotropic salts, which can increase the solubility of organic materials in aqueous solutions, are useful to tertiary oil recovery. We have examined effects on solubility of hydrocarbons in water (with and without alcohols) through addition of inorganic hydrotropic salts, such as perchlorates, thiocyanates, and iodides - high in the usual Hofmeister series - and of organic salts such as short chain alkyl benzene sulfonates and other salts based on substituted benzene derivatives. Although the inorganic salts are relatively ineffective in increasing solubility of hydrocarbons in water, many of the organic salts are excellent hydrotropic agents for hydrocarbons. We have examined the phase relationships for several series of aromatic salts such as sulfonates, carboxylates and hydroxycarboxylates, as a function of alkyl-carbon substitution in three-component (hydrocarbon, salt, water) and in four-component (hydrocarbon, salt, alcohol, water) systems. We have also examined miscibility relationships for a given hydrotropic salt as the chain length of alkanes and alkyl benzenes is systematically varied. While miscibilities decrease with increase in chain length of the hydrocarbon, the hydrotropic properties in these systems increase rapidly with the number of alkyl carbons on the benzene ring of the salts and they are relatively insensitive to the type of charged group (sulfonate vs carboxylate) attached to the benzene ring. However, there were significant increases in hydrotropy as one goes from equally substituted sulfonates or carboxylates to salicylates. A number of salts have been identified which have much greater hydrotropic properties for hydrocarbons than such well-known hydrotropic materials as toluene and xylene sulfonates.

  18. Acrolein cytotoxicity in hepatocytes involves endoplasmic reticulum stress, mitochondrial dysfunction and oxidative stress

    SciTech Connect (OSTI)

    Mohammad, Mohammad K.; Alcohol Research Center, University of Louisville ; Avila, Diana; Department of Pharmacology and Toxicology, University of Louisville; Alcohol Research Center, University of Louisville ; Zhang, Jingwen; Alcohol Research Center, University of Louisville ; Barve, Shirish; Department of Pharmacology and Toxicology, University of Louisville; Alcohol Research Center, University of Louisville ; Arteel, Gavin; Alcohol Research Center, University of Louisville ; McClain, Craig; Department of Pharmacology and Toxicology, University of Louisville; Alcohol Research Center, University of Louisville; Robley Rex VAMC, Louisville, KY ; Joshi-Barve, Swati; Department of Pharmacology and Toxicology, University of Louisville; Alcohol Research Center, University of Louisville

    2012-11-15

    Acrolein is a common environmental, food and water pollutant and a major component of cigarette smoke. Also, it is produced endogenously via lipid peroxidation and cellular metabolism of certain amino acids and drugs. Acrolein is cytotoxic to many cell types including hepatocytes; however the mechanisms are not fully understood. We examined the molecular mechanisms underlying acrolein hepatotoxicity in primary human hepatocytes and hepatoma cells. Acrolein, at pathophysiological concentrations, caused a dose-dependent loss of viability of hepatocytes. The death was apoptotic at moderate and necrotic at high concentrations of acrolein. Acrolein exposure rapidly and dramatically decreased intracellular glutathione and overall antioxidant capacity, and activated the stress-signaling MAP-kinases JNK, p42/44 and p38. Our data demonstrate for the first time in human hepatocytes, that acrolein triggered endoplasmic reticulum (ER) stress and activated eIF2?, ATF-3 and -4, and Gadd153/CHOP, resulting in cell death. Notably, the protective/adaptive component of ER stress was not activated, and acrolein failed to up-regulate the protective ER-chaperones, GRP78 and GRP94. Additionally, exposure to acrolein disrupted mitochondrial integrity/function, and led to the release of pro-apoptotic proteins and ATP depletion. Acrolein-induced cell death was attenuated by N-acetyl cysteine, phenyl-butyric acid, and caspase and JNK inhibitors. Our data demonstrate that exposure to acrolein induces a variety of stress responses in hepatocytes, including GSH depletion, oxidative stress, mitochondrial dysfunction and ER stress (without ER-protective responses) which together contribute to acrolein toxicity. Our study defines basic mechanisms underlying liver injury caused by reactive aldehyde pollutants such as acrolein. -- Highlights: ? Human primary hepatocytes and cultured cell lines are used. ? Multiple cell death signaling pathways are activated by acrolein. ? Novel finding of acrolein-induced ER stress ? Acrolein fails to activate ER stress-induced protective responses. ? Combinatorial therapies may be needed for preventing acrolein hepatotoxicity.

  19. PERMITTING OF A PROJECT INVOLVING HYDROGEN: A CODE OFFICIAL’S PERSPECTIVE

    SciTech Connect (OSTI)

    Kallman, Richard A.; Barilo, Nick F.; Murphy, W. F.

    2012-05-11

    Recent growth in the development of hydrogen infrastructure has led to more requests for code officials to approve hydrogen-related projects and facilities. To help expedite the review and approval process, significant efforts have been made to educate code officials on permitting hydrogen vehicle fueling stations and facilities using stationary fuel cells (e.g., backup power for telephone cell tower sites). Despite these efforts, project delays continue because of several factors, including the limited experience of code officials with these types of facilities, submittals that lack the required information (including failure to adequately address local requirements), and submission of poor quality documents. The purpose of this paper is to help project proponents overcome these potential roadblocks and obtain timely approval for a project. A case study of an actual stationary application permitting request is provided to illustrate the value of addressing these issues.

  20. Contract administration involving the remedial investigation and feasibility study at the Feed Materials Production Center

    SciTech Connect (OSTI)

    Not Available

    1991-08-28

    Advanced Sciences, Incorporated (ASI), has been performing a Remedial Investigation and Feasibility Study (RI/FS) at the Feed Materials Production Center (Fernald Facility) at Fernald, Ohio, under an 8 (a) contract with the US Small Business Administration (SBA). The Fernald Facility is a Government-owned facility operated by Westinghouse Materials Company of Ohio (WMCO) under a management and operating contract. The objective of this audit was to evaluate the award and administration of the ASI contract.

  1. Differing Professional Opinions for Technical Issues Involving Environment, Safety and Health

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2011-07-29

    The Order establishes the DOE Differing Professional Opinion process for employees to raise technical concerns related to environment, safety, and health which cannot be resolved using routine processes. Supersedes DOE P 442.1 and DOE M 442.1-1.

  2. Physical processes involved in strip electrode welding using the method of slatted splicing

    SciTech Connect (OSTI)

    Bushma, V. O. [Moscow State Technological University 'Stankin' (Russian Federation)

    2010-12-15

    Physical processes that take place in a strip electrode during welding using the slatted splicing technique are considered. Flowing of the welding current in the electrode is shown to be the key process which determines electrode heating and melting. Technological receipts are proposed that allow obtaining high-quality welds by the method of slatted splicing.

  3. Global prevalence and distribution of genes and microorganisms involved in mercury methylation

    SciTech Connect (OSTI)

    Podar, Mircea; Gilmour, C C; Brandt, Craig C; Bullock, Allyson L; Brown, Steven D; Crable, Bryan R; Palumbo, Anthony Vito; Somenahally, Anil C; Elias, Dwayne A

    2015-01-01

    Mercury methylation produces the neurotoxic, highly bioaccumulative methylmercury (MeHg). Recent identification of the methylation genes (hgcAB) provides the foundation for broadly evaluating microbial Hg-methylation potential in nature without making explicit rate measurements. We queried hgcAB diversity and distribution in all available microbial metagenomes, encompassing most environments. The genes were found in nearly all anaerobic, but not in aerobic, environments including oxygenated layers of the open ocean. Critically, hgcAB was effectively absent in ~1500 human microbiomes, suggesting a low risk of endogenous MeHg production. New potential methylation habitats were identified, including invertebrate guts, thawing permafrost, coastal dead zones , soils, sediments, and extreme environments, suggesting multiple routes for MeHg entry into food webs. Several new taxonomic groups potentially capable of Hg-methylation emerged, including lineages having no cultured representatives. We begin to address long-standing evolutionary questions about Hg-methylation and ancient carbon fixation mechanisms while generating a new global view of Hg-methylation potential.

  4. High-performance ternary blend polymer solar cells involving both energy transfer and hole relay processes

    SciTech Connect (OSTI)

    Lu, Luyao; Chen, Wei; Xu, Tao; Yu, Luping

    2015-06-04

    The integration of multiple materials with complementary absorptions into a single junction device is regarded as an efficient way to enhance the power conversion efficiency (PCE) of organic solar cells (OSCs). However, because of increased complexity with one more component, only limited high-performance ternary systems have been demonstrated previously. Here we report an efficient ternary blend OSC with a PCE of 9.2%. We show that the third component can reduce surface trap densities in the ternary blend. Detailed studies unravel that the improved performance results from synergistic effects of enlarged open circuit voltage, suppressed trap-assisted recombination, enhanced light absorption, increased hole extraction, efficient energy transfer and better morphology. The working mechanism and high device performance demonstrate new insights and design guidelines for high-performance ternary blend solar cells and suggest that ternary structure is a promising platform to boost the efficiency of OSCs.

  5. Issues Associated with IAEA Involvement in Assured Nuclear Fuel Supply Arrangements

    SciTech Connect (OSTI)

    Kessler, Carol E.; Mathews, Carrie E.

    2008-02-08

    Assured nuclear fuel supply has been discussed at various times as a mechanism to help limit expansion of enrichment and reprocessing (E&R) capability beyond current technology holders. Given the events in the last few years in North Korea and Iran, concern over weapons capabilities gained from acquisition of E&R capabilities has heightened and brought assured nuclear fuel supply (AFS) again to the international agenda. Successful AFS programs can be valuable contributions to strengthening the nonproliferation regime and helping to build public support for expanding nuclear energy.

  6. Discovery of a new ATP-binding motif involved in peptidic azoline...

    Office of Scientific and Technical Information (OSTI)

    OSTI Identifier: 1163365 Resource Type: Journal Article Resource Relation: Journal Name: Nat. Chem. Biol.; Journal Volume: 10; Journal Issue: 10, 2014 Research Org: Advanced Photon ...

  7. Local government involvement in long term resource planning for community energy systems

    SciTech Connect (OSTI)

    Not Available

    1992-03-01

    A program was developed to coordinate governmental, research, utility, and business energy savings efforts, and to evaluate future potential actions, based on actual field data obtained during the implementation of Phase I of the State Resource Plan. This has lead to the establishment of a state conservation and energy efficiency fund for the purpose of establishing a DSM Program. By taking a state wide perspective on resource planning, additional savings, including environmental benefits, can be achieved through further conservation and demand management. This effort has already blossomed into a state directive for DSM programs for the natural gas industry.

  8. Local government involvement in long term resource planning for community energy systems. Demand side management

    SciTech Connect (OSTI)

    Not Available

    1992-03-01

    A program was developed to coordinate governmental, research, utility, and business energy savings efforts, and to evaluate future potential actions, based on actual field data obtained during the implementation of Phase I of the State Resource Plan. This has lead to the establishment of a state conservation and energy efficiency fund for the purpose of establishing a DSM Program. By taking a state wide perspective on resource planning, additional savings, including environmental benefits, can be achieved through further conservation and demand management. This effort has already blossomed into a state directive for DSM programs for the natural gas industry.

  9. Climate Change Scenario Planning in Alaska's National Parks: Stakeholder Involvement in the Decision-Making Process

    SciTech Connect (OSTI)

    Ernst, Kathleen M; Van Riemsdijk, Dr. Micheline

    2013-01-01

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decision-making process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  10. Climate change scenario planning in Alaska's National Parks: Stakeholder involvement in the decision-making process

    SciTech Connect (OSTI)

    Ernst, Kathleen M; Van Riemsdijk, Dr. Micheline

    2013-01-01

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decisionmaking process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  11. Summary of Interim Policy on CERCLA Settlements Involving Municipalities and Municipal Wastes. Fact sheet

    SciTech Connect (OSTI)

    Not Available

    1991-05-01

    The Fact Sheet addresses a consistent agency-wide approach for addressing municipalities and municipal wastes in the Superfund settlement process. The policy also addresses settlements with private generators and transporters of hazardous waste trash derived from a commercial, institutional, or industrial process or activity.

  12. Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase...

    Office of Scientific and Technical Information (OSTI)

    OSTI Identifier: 1088585 Resource Type: Journal Article Resource Relation: Journal Name: Biochemistry-US; Journal Volume: 52; Journal Issue: (26) ; 07, 2013 Research Org: Advanced ...

  13. Overview of Scientific Issues Involved in Selection of Polymers for PV Applications: Preprint

    SciTech Connect (OSTI)

    Kempe, M.

    2011-07-01

    Encapsulant materials used in photovoltaic (PV) modules serve multiple purposes. They physically hold components in place, provide electrical insulation, reduce moisture ingress, optically couple superstrate materials (e.g., glass) to PV cells, protect components from mechanical stress by mechanically de-coupling components via strain relief, and protect materials from corrosion. To do this, encapsulants must adhere well to all surfaces, remain compliant, and transmit light after exposure to temperature, humidity, and UV radiation histories. Here, a brief review of some of the polymeric materials under consideration for PV applications is provided, with an explanation of some of their advantages and disadvantages.

  14. E-cadherin junction formation involves an active kinetic nucleation process

    SciTech Connect (OSTI)

    Biswas, Kabir H.; Hartman, Kevin L.; Yu, Cheng -han; Harrison, Oliver J.; Song, Hang; Smith, Adam W.; Huang, William Y. C.; Lin, Wan -Chen; Guo, Zhenhuan; Padmanabhan, Anup; Troyanovsky, Sergey M.; Dustin, Michael L.; Shapiro, Lawrence; Honig, Barry; Zaidel-Bar, Ronen; Groves, Jay T.

    2015-08-19

    Epithelial (E)-cadherin-mediated cell–cell junctions play important roles in the development and maintenance of tissue structure in multicellular organisms. E-cadherin adhesion is thus a key element of the cellular microenvironment that provides both mechanical and biochemical signaling inputs. Here, we report in vitro reconstitution of junction-like structures between native E-cadherin in living cells and the extracellular domain of E-cadherin in a supported membrane. Junction formation in this hybrid live cell-supported membrane configuration requires both active processes within the living cell and a supported membrane with low E-cad-ECD mobility. The hybrid junctions recruit α-catenin and exhibit remodeled cortical actin. Observations suggest that the initial stages of junction formation in this hybrid system depend on the trans but not the cis interactions between E-cadherin molecules, and proceed via a nucleation process in which protrusion and retraction of filopodia play a key role.

  15. Directory of DOE and contractor personnel involved in non-government standards activities

    SciTech Connect (OSTI)

    1995-08-01

    This document contains a listing of DOE employees and DOE contractors who have submitted form DOE F 1300.2, Record of Non-Government Standards Activity. Additional names were added from rosters supplied by non-Government standards bodies.

  16. Phase-Changing Ionic Liquids: CO2 Capture with Ionic Liquids Involving Phase Change

    SciTech Connect (OSTI)

    2010-07-01

    IMPACCT Project: Notre Dame is developing a new CO2 capture process that uses special ionic liquids (ILs) to remove CO2 from the gas exhaust of coal-fired power plants. ILs are salts that are normally liquid at room temperature, but Notre Dame has discovered a new class of ILs that are solid at room temperature and change to liquid when they bind to CO2. Upon heating, the CO2 is released for storage, and the ILs re-solidify and donate some of the heat generated in the process to facilitate further CO2 release. These new ILs can reduce the energy required to capture CO2 from the exhaust stream of a coal-fired power plant when compared to state-ofthe- art technology.

  17. Global prevalence and distribution of genes and microorganisms involved in mercury methylation

    SciTech Connect (OSTI)

    Podar, Mircea; Gilmour, C. C.; Brandt, Craig C.; Soren, Allyson; Brown, Steven D.; Crable, Bryan R.; Palumbo, Anthony Vito; Somenahally, Anil C.; Elias, Dwayne A.

    2015-01-01

    Mercury methylation produces the neurotoxic, highly bioaccumulative methylmercury (MeHg). Recent identification of the methylation genes (hgcAB) provides the foundation for broadly evaluating microbial Hg-methylation potential in nature without making explicit rate measurements. We first queried hgcAB diversity and distribution in all available microbial metagenomes, encompassing most environments. The genes were found in nearly all anaerobic, but not in aerobic, environments including oxygenated layers of the open ocean. Critically, hgcAB was effectively absent in ~1500 human microbiomes, suggesting a low risk of endogenous MeHg production. New potential methylation habitats were identified, including invertebrate guts, thawing permafrost, coastal dead zones, soils, sediments, and extreme environments, suggesting multiple routes for MeHg entry into food webs. Several new taxonomic groups potentially capable of Hg-methylation emerged, including lineages having no cultured representatives. We then begin to address long-standing evolutionary questions about Hg-methylation and ancient carbon fixation mechanisms while generating a new global view of Hg-methylation potential.

  18. Hydrogenolysis of 5-carbon sugars, sugar alcohols, and other methods and compositions for reactions involving hydrogen

    DOE Patents [OSTI]

    Werpy, Todd A [West Richland, WA; Zacher, Alan H [Kennewick, WA

    2002-11-12

    Methods and compositions for reactions of hydrogen over a Re-containing catalyst with compositions containing a 5-carbon sugar, sugar alcohol, or lactic acid are described. It has been surprisingly discovered that reaction with hydrogen over a Re-containing multimetallic catalyst resulted in superior conversion and selectivity to desired products such as propylene glycol. A process for the synthesis of PG from lactate or lactic acid is also described.

  19. Hydrogenolysis Of 5-Carbon Sugars, Sugar Alcohols And Compositions For Reactions Involving Hydrogen

    DOE Patents [OSTI]

    Werpy, Todd A.; Frye, Jr., John G.; Zacher, Alan H.; Miller, Dennis J.

    2004-01-13

    Methods and compositions for reactions of hydrogen over a Re-containing catalyst with compositions containing a 5-carbon sugar, sugar alcohol, or lactic acid are described. It has been surprisingly discovered that reaction with hydrogen over a Re-containing multimetallic catalyst resulted in superior conversion and selectivity to desired products such as propylene glycol. A process for the synthesis of PG from lactate or lactic acid is also described.

  20. Response and Notification Procedures for Data Breaches Involving Personally Identifiable Information

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2007-10-09

    This Notice concerns actions to address data breaches of personally identifiable information that is collected, processed or maintained by DOE. Extended by DOE N 251.73 until 1-9-09. No cancellation.

  1. Redox linked flavin sites in extracellular decaheme proteins involved in microbe-mineral electron transfer.

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Edwards, Marcus J.; White, Gaye F.; Norman, Michael; Tome-Fernandez, Alice; Ainsworth, Emma; Shi, Liang; Fredrickson, Jim K.; Zachara, John M.; Butt, Julea N.; Richardson, David J.; et al

    2015-07-01

    Extracellular microbe-mineral electron transfer is a major driving force for the oxidation of organic carbon in many subsurface environments. Extracellular multi-heme cytochromes of the Shewenella genus play a major role in this process but the mechanism of electron exchange at the interface between cytochrome and acceptor is widely debated. The 1.8 Å x-ray crystal structure of the decaheme MtrC revealed a highly conserved CX₈C disulfide that, when substituted for AX₈A, severely compromised the ability of S. oneidensis to grow under aerobic conditions. Reductive cleavage of the disulfide in the presence of flavin mononucleotide (FMN) resulted in the reversible formation ofmore » a stable flavocytochrome. Similar results were also observed with other decaheme cytochromes, OmcA, MtrF and UndA. The data suggest that these decaheme cytochromes can transition between highly reactive flavocytochromes or less reactive cytochromes, and that this transition is controlled by a redox active disulfide that responds to the presence of oxygen.« less

  2. E-cadherin junction formation involves an active kinetic nucleation process

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Biswas, Kabir H.; Hartman, Kevin L.; Yu, Cheng -han; Harrison, Oliver J.; Song, Hang; Smith, Adam W.; Huang, William Y. C.; Lin, Wan -Chen; Guo, Zhenhuan; Padmanabhan, Anup; et al

    2015-08-19

    Epithelial (E)-cadherin-mediated cell–cell junctions play important roles in the development and maintenance of tissue structure in multicellular organisms. E-cadherin adhesion is thus a key element of the cellular microenvironment that provides both mechanical and biochemical signaling inputs. Here, we report in vitro reconstitution of junction-like structures between native E-cadherin in living cells and the extracellular domain of E-cadherin in a supported membrane. Junction formation in this hybrid live cell-supported membrane configuration requires both active processes within the living cell and a supported membrane with low E-cad-ECD mobility. The hybrid junctions recruit α-catenin and exhibit remodeled cortical actin. Observations suggest thatmore » the initial stages of junction formation in this hybrid system depend on the trans but not the cis interactions between E-cadherin molecules, and proceed via a nucleation process in which protrusion and retraction of filopodia play a key role.« less

  3. On computing stress in polymer systems involving multi-body potentials from molecular dynamics simulation

    SciTech Connect (OSTI)

    Fu, Yao E-mail: jhsong@cec.sc.edu; Song, Jeong-Hoon E-mail: jhsong@cec.sc.edu

    2014-08-07

    Hardy stress definition has been restricted to pair potentials and embedded-atom method potentials due to the basic assumptions in the derivation of a symmetric microscopic stress tensor. Force decomposition required in the Hardy stress expression becomes obscure for multi-body potentials. In this work, we demonstrate the invariance of the Hardy stress expression for a polymer system modeled with multi-body interatomic potentials including up to four atoms interaction, by applying central force decomposition of the atomic force. The balance of momentum has been demonstrated to be valid theoretically and tested under various numerical simulation conditions. The validity of momentum conservation justifies the extension of Hardy stress expression to multi-body potential systems. Computed Hardy stress has been observed to converge to the virial stress of the system with increasing spatial averaging volume. This work provides a feasible and reliable linkage between the atomistic and continuum scales for multi-body potential systems.

  4. Collective properties of the final state in processes involving the production of hadron jets

    SciTech Connect (OSTI)

    Okorokov, V. A. Ponosov, A. K.

    2013-10-15

    Experimental results obtained by studying soft hadron jets in pion-proton and pion-nucleus reactions at intermediate energies with the aid of traditional collective variables are presented. Analytic approximations that describe, at a qualitative level, the dependences of collective parameters on the energy and multiplicity are proposed. Estimates obtained for strong coupling constant by studying collective variables are in reasonable agreement with its world-average value and with the results extracted by using different methods. The behavior of traditional collective variables as functions of the multiplicity in various interactions makes it possible to obtain a universal estimate for the lower boundary of the region of experimental manifestations of jets in multiparticle-production processes.

  5. Environmental diagnostic analysis of ground water bacteria and their involvement in utilization of aromatic compounds

    SciTech Connect (OSTI)

    Wear, J.E. Jr.

    1993-05-01

    The objective of this study was to examine the hypothesis that select functional groups of bacteria from pristine sites have an innate ability to degrade synthetic aromatics that often contaminate groundwater environments,due to exposure to naturally occurring recalcitrant aromatics in their environment. This study demonstrates that subsurface microbial communities are capable of utilizing lignin and humic acid breakdown products. Utilizers of these compounds were found to be present in most all the wells tested. Even the deepest aquifer tested had utilizers present for all six of the aromatics tested. Highest counts for the aromatics tested were observed with the naturally occurring breakdown products of either lignin or humic acid. Carboxylic acids were found to be an important sole carbon source for groundwater bacteria possibly explained by the fact that they are produced by the oxidative cleavage of aromatic ring structures. The carbohydrate sole carbon sources that demonstrated the greatest densities were ones commonly associated with humics. This study indicates that utilization of naturally occurring aromatic compounds in the subsurface is an important nutritional source for groundwater bacteria. In addition, it suggests that adaptation to naturally occurring recalcitrant substrates is the origin of degradative pathways for xenobiotic compounds with analogous structure. This work has important implications for in situ bioremediation as a method of environmental cleanup.

  6. SO2907, A Putative TonB-dependent Receptor, Is Involved in Dissimilato...

    Office of Scientific and Technical Information (OSTI)

    Many of the biological components that interact with the various iron forms are proposed to be localized in these membrane fractions. To identify the iron-binding proteins acting ...

  7. IDENTIFICATION AND CHARACTERIZATION OF THERMOBIFIDA FUSCA GENES INVOLVED IN PLANT CELL WALL DEGRADATION.

    SciTech Connect (OSTI)

    David B. Wilson

    2006-01-23

    Micro-array experiments identified a number of Thermobifida fusca genes which were upregulated by growth on cellulose or plant biomass. Five of these genes were cloned, overexpressed in E. coli and the expressed proteins were purified and characterized. These were a xyloglucanase,a 1-3,beta glucanase, a family 18 hydrolase and twocellulose binding proteins that contained no catalytic domains. The catalyic domain of the family 74 endoxyloglucanase with a C-terminal, cellulose binding module was crystalized and its 3-dimensional structure was determined by X-ray crystallography.

  8. Structures of the PelD Cyclic Diguanylate Effector Involved in...

    Office of Scientific and Technical Information (OSTI)

    Journal Issue: (36) ; 08, 2013 Publisher: American Society for Biochemistry and Molecular Biology Research Org: Advanced Photon Source (APS), Argonne National Laboratory (ANL), ...

  9. Redox linked flavin sites in extracellular decaheme proteins involved in microbe-mineral electron transfer.

    SciTech Connect (OSTI)

    Edwards, Marcus J.; White, Gaye F.; Norman, Michael; Tome-Fernandez, Alice; Ainsworth, Emma; Shi, Liang; Fredrickson, Jim K.; Zachara, John M.; Butt, Julea N.; Richardson, David J.; Clarke, Thomas A.

    2015-07-01

    Extracellular microbe-mineral electron transfer is a major driving force for the oxidation of organic carbon in many subsurface environments. Extracellular multi-heme cytochromes of the Shewenella genus play a major role in this process but the mechanism of electron exchange at the interface between cytochrome and acceptor is widely debated. The 1.8 Å x-ray crystal structure of the decaheme MtrC revealed a highly conserved CX₈C disulfide that, when substituted for AX₈A, severely compromised the ability of S. oneidensis to grow under aerobic conditions. Reductive cleavage of the disulfide in the presence of flavin mononucleotide (FMN) resulted in the reversible formation of a stable flavocytochrome. Similar results were also observed with other decaheme cytochromes, OmcA, MtrF and UndA. The data suggest that these decaheme cytochromes can transition between highly reactive flavocytochromes or less reactive cytochromes, and that this transition is controlled by a redox active disulfide that responds to the presence of oxygen.

  10. High-performance ternary blend polymer solar cells involving both energy transfer and hole relay processes

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lu, Luyao; Chen, Wei; Xu, Tao; Yu, Luping

    2015-06-04

    The integration of multiple materials with complementary absorptions into a single junction device is regarded as an efficient way to enhance the power conversion efficiency (PCE) of organic solar cells (OSCs). However, because of increased complexity with one more component, only limited high-performance ternary systems have been demonstrated previously. Here we report an efficient ternary blend OSC with a PCE of 9.2%. We show that the third component can reduce surface trap densities in the ternary blend. Detailed studies unravel that the improved performance results from synergistic effects of enlarged open circuit voltage, suppressed trap-assisted recombination, enhanced light absorption, increasedmore » hole extraction, efficient energy transfer and better morphology. The working mechanism and high device performance demonstrate new insights and design guidelines for high-performance ternary blend solar cells and suggest that ternary structure is a promising platform to boost the efficiency of OSCs.« less

  11. Technology Deployment Annual Report 2009

    SciTech Connect (OSTI)

    Keith Arterburn

    2009-12-01

    Idaho National Laboratory (INL) is a Department of Energy (DOE) multi-program national laboratory that conducts research and development in all DOE mission areas. Like all other federal laboratories, INL has a statutory, technology transfer mission to make its capabilities and technologies available to all federal agencies, to state and local governments, and to universities and industry. To fulfill this mission, INL encourages its scientific, engineering, and technical staff to disclose new inventions and creations to ensure the resulting intellectual property is captured, protected, and made available to others who might benefit from it. As part of the mission, intellectual property is licensed to industrial partners for commercialization, creating jobs and delivering the benefits of federally funded technology to consumers. In other cases, unique capabilities are made available to other federal agencies or to regional small businesses to solve specific technical challenges. In other interactions, INL employees work cooperatively with researchers and other technical staff of our partners to further develop emerging technologies. This report is a catalog of selected INL technology transfer and commercialization transactions during this past year. The size and diversity of INL technical resources, coupled with the large number of relationships with other organizations, virtually ensures that a report of this nature will fail to capture all interactions. Recognizing this limitation, this report focuses on transactions that are specifically authorized by technology transfer legislation (and corresponding contractual provisions) or involve the transfer of legal rights to technology to other parties.

  12. This invention relates to methods of generating NP gallium nitride (GaN) across large areas (>1 cm.sup.2) with controlled pore diameters, pore density, and porosity. Also disclosed are methods of generating novel optoelectronic devices based on porous GaN. Additionally a layer transfer scheme to separate and create free-standing crystalline GaN thin layers is disclosed that enables a new device manufacturing paradigm involving substrate recycling. Other disclosed embodiments of this invention relate to fabrication of GaN based nanocrystals and the use of NP GaN electrodes for electrolysis, water splitting, or photosynthetic process applications.

    DOE Patents [OSTI]

    Zhang, Yu; Sun, Qian; Han, Jung

    2015-12-08

    This invention relates to methods of generating NP gallium nitride (GaN) across large areas (>1 cm.sup.2) with controlled pore diameters, pore density, and porosity. Also disclosed are methods of generating novel optoelectronic devices based on porous GaN. Additionally a layer transfer scheme to separate and create free-standing crystalline GaN thin layers is disclosed that enables a new device manufacturing paradigm involving substrate recycling. Other disclosed embodiments of this invention relate to fabrication of GaN based nanocrystals and the use of NP GaN electrodes for electrolysis, water splitting, or photosynthetic process applications.

  13. An institutional design for an electricity contract market with central dispatch

    SciTech Connect (OSTI)

    Chao, Hung-po; Peck, S.

    1997-02-01

    Chao and Peck (1996) introduce a new approach to the design of an efficient market that explicitly incorporates these externalities so that market efficiency can be restored. The main idea is the introduction of tradable transmission capacity rights that closely match physical power flows and a trading rule that codifies the effects of power transfers on power flows and transmission losses throughout the network in a way that is consistent with the physical laws. The trading rule specifies the transmission capacity rights and transmission loss compensation required for electricity transactions. It is demonstrated that the market mechanism will produce an efficient allocation in equilibrium, and a dynamic trading process that involves electricity trading and transmission bidding will converge to a market equilibrium in a stable manner. 11 refs., 6 figs., 5 tabs.

  14. Draft framework for watershed-based trading

    SciTech Connect (OSTI)

    1996-05-30

    Effluent trading is an innovative way for water quality agencies and community stakeholders to develop common-sense, cost-effective solutions for water quality problems in their watersheds. Trading can allow communities to grow and prosper while retaining their commitment to water quality. The bulk of this framework discusses effluent trading in watersheds. Remaining sections discuss transactions that, while not technically fulfilling the definition of `effluent` trade, do involve the exchange of valued water quality or other ecological improvements between partners responding to market initiatives. This document therefore includes activities such as trades within a facility (intra-plant trading) and wetland mitigation banking, effluent trading/watersheds/watershed management/water quality protection/water quality management.

  15. DOE Issues Request for Information for Richland Operations Office Richland

    Energy Savers [EERE]

    Guidance for "Other Transactions" DOE Issues Guidance for "Other Transactions" November 15, 2005 - 12:42pm Addthis Provides Opportunity for Increased Industry Research Partnerships WASHINGTON, DC - On November 7, 2005, the Department of Energy (DOE) issued an interim final rule for the establishment of policies and procedures for a new "other transaction" authority. This authority allows DOE to remove barriers to commercial firms' participation in some of DOE's

  16. Directory of Small Business Program Managers (SBPMs)

    Energy Savers [EERE]

    Direct Heating Equipment- v1.0 Direct Heating Equipment- v1.0 File Direct Heating Equipment - v1.0 More Documents & Publications Refrigerators and Refrigerator-Freezers (Appendix A1 after May 2, 2011) Residential Refrigerators-Freezers (Appendix A1) Residential Clothes Washers (Appendix J2)

    Direct Research & Development Transactions Direct Research & Development Transactions DOE direct research and development transactions include contracts, grants, and cooperative agreements, and

  17. Part B - Requirements & Funding Information PART B - Requirements and Funding Information

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    b. Part B 1 Part B - Requirements & Funding Information PART B - Requirements and Funding Information Gray highlights are instructions. Remove the instructions from the interagency agreement. Attachment 3.b. Part B 2 PART B - Requirements & Funding Information B.1. Purpose This is an interagency transaction. An interagency transaction is an intra-governmental transaction when the servicing agency uses internal resources to support the requesting agency requirement and is a reimbursable

  18. Acquisition Letter No. AL 2016-01 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    FROM: Chief Contract and Financial Assistance Policy Division Office of Policy Office of ... move from DOE traditional transactional approach for approving certain costs relating to ...

  19. Section II INT

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (11-03-2010) Title: Standard Terms & Conditions for International Commercial Transactions Owner: Procurement Policy & Quality Dept Initial Release Date: 11310 Page 1 of 8...

  20. Presentation title: This can be up to 2 lines

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    ... and which can be levered to cover larger related transactions * Purpose Allow efficient price discovery * Characteristics - sufficient liquidity to eliminate distortions & ...

  1. Ekdahl named IEEE Fellow

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in 1975. His research includes high energy density plasmas and hydrodynamics, pulsed ... Charged Particle Beams and Sources section of the IEEE Transactions on Plasma Science. ...

  2. Under the recently passed American Recovery and Reinvestment...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    - Examine the use of funds by contract and grant recipients through transaction testing. The Office of Investigations will provide an aggressive law enforcement presence for ...

  3. CBEI Broker Training Project

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    investments through better informed market participants. 3 Approach Approach: ... attend a course about energy- efficiency because they are generally transaction-oriented. ...

  4. QBR Follow Ups

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    servers, InfoSphere(tm) software, cyber security, architect of interoperable transactive signal system - Netezza: highly parallel data storage appliance located in demonstration's...

  5. BPA-2014-01761-FOIA Response

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rental agreements, sale agreements, contracts, deeds, and other documents setting forth financial transactions or agreements between BPA and any other entity over the last...

  6. BPA-2014-01761-FOIA Correspondence

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rental agreements, sale agreements, contracts, deeds, and other documents setting forth financial transactions or agreements between BPA and any other entity over the last...

  7. TO: Procurement Directors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    property; provided protocols for foreign transactions (loans, transfers, ... The revision also removed outdated and conflicting language. DOE O 580.1A was also ...

  8. Home Improvement Catalyst: Strategy and Framework

    Broader source: Energy.gov [DOE]

    To identify and prioritize activities where DOE can have the greatest impact in accelerating adoption of energy efficient measures at key home improvement transactions.

  9. Volttron (TM) Security Features and Discussions

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Laboratory Software Framework for Transactive Energy: VOLTTRON(tm), VTARI, Arlington, VA July 29, 2015 1 PNNL-SA-111786 VOLTTRON Team July 29, 2015 2 Software Development ...

  10. Office of the Assistant General Counsel for Technology Transfer...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    This site includes information pertaining to disposition of intellectual property rights ... Transactions, Technology and Contractor Human Resources About Us Intellectual Property ...

  11. PRIVACY IMPACT ASSESSMENT: Integrated Safety Management Workshop

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Idaho National Laboratory Engineering Research Office ... but not limited to, education, financial transactions, ... be written in plain language and at a high level so ...

  12. NBGI International | Open Energy Information

    Open Energy Info (EERE)

    London, United Kingdom Zip: EC4V 4BJ Sector: Services Product: NBGI is the leading investment bank providing a full range of investment banking services, including transaction...

  13. GUIDANCE FOR STATE ENERGY PROGRAM GRANTEES ON SUB-RECIPIENT MONITORING...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Fluorescent electronic lighting ballasts, LED traffic lights and crosswalk signals, ... Review books of account, audit reports, etc. Determine that accounting transactions are ...

  14. New Approach to Determine the Need for Operating Reserves in...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    In Dynamic Scheduling of Operating Reserves in Co-Optimized Electricity Markets With Wind Power, an article published in the January 2014 issue of IEEE Transactions on Power ...

  15. Test results of a Nb3Al/Nb3Sn subscale magnet for accelerator...

    Office of Scientific and Technical Information (OSTI)

    Type: Accepted Manuscript Journal Name: IEEE Transactions on Applied Superconductivity ... Publisher: Institute of Electrical and Electronics Engineers (IEEE) Research Org: Lawrence ...

  16. Operations Research Analyst

    Broader source: Energy.gov [DOE]

    This position is located in the Market Analysis and Pricing (PTM) group in the Power Services Organization. Market Analysis and Pricing performs market analysis, product pricing, transaction and...

  17. RAPID/Best Practices/Online Permitting Systems | Open Energy...

    Open Energy Info (EERE)

    agencies using the software to process NEPA transactions, costs vary by the numbers of different project types tracked and by the volume of requests processed through the...

  18. Generation and Transmission Maximization Model | Open Energy...

    Open Energy Info (EERE)

    its limited energy and transmission resources, but also firm contracts, independent power producer (IPP) agreements, and bulk power transaction opportunities on the spot...

  19. Deep Drilling to the Magmatic Environment in Long Valley Caldera...

    Open Energy Info (EERE)

    and eventually into this magma body. Authors John B. Rundle, Charles R. Carrigan, Harry C. Hardee and William C. Luth Published Journal EOS, Transactions American Geophysical...

  20. Structure, Stratigraphy, and Tectonics of the Dixie Valley Geothermal...

    Open Energy Info (EERE)

    and Tectonics of the Dixie Valley Geothermal Site, Dixie Valley, Nevada Author Gabriel L. Plank Published Journal Geothermal Resources Council Transactions, 1995 DOI Not...

  1. Nug_Network_100308.ppt

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protocols * ssh, scp, rsync * X11, xemacs, totalview and other transactional protocols * ftp * gridftp * bbcp * hsi, htar 3 Common Bottlenecks * Latency * Congestion, small pipes...

  2. Microsoft PowerPoint - 5_Brian and Pete_Year In ReviewNMMSS2013...

    National Nuclear Security Administration (NNSA)

    NMMSS Timeline Year Activity 1964 System development began at Oak Ridge, Tennessee 1965 Inventory and MBR data were added to the system 1968 Transaction data collection began...

  3. Contractor Past Performance Information

    Broader source: Energy.gov (indexed) [DOE]

    a. Part A. b. Part B. 2. Interagency agreement format and samples. a. STRIPES IA funds out templates for interagency assisted acquisitions and interagency transactions....

  4. The generation fleet in MISO is being affected by time, fuel...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Seam - Joint and Common Market process is making progress on a number of issues - Interchange Optimization - Coordinated Transaction Scheduling - Cross Border Planning * SPP Seam ...

  5. Building Energy Asset Score

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    energy efficiency in real estate transactions and spur investment in capital improvements. ... Property Trust * Marriott International * Marx Okubo * National Oceanic and Atmospheric ...

  6. Chemical and Isotopic Composition of Casa Diablo Hot Spring:...

    Open Energy Info (EERE)

    of Casa Diablo Hot Spring: Magmatic CO2 near Mammoth Lakes, CA. In: EOS, Transactions. () ; 021983; () . () : American Geophysical Union; p. 58 Related Geothermal...

  7. 150122 Traxys DOE RFI Comments

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    in the sale and introduction to market of the ... have actual transactional data on how, when and where the ... the domestic uranium mining, conversion and enrichment ...

  8. Buildings-to-Grid Technical Opportunities: From the Grid Perspective

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    a transactive energy ecosystem requires new approaches to planning ... the bulk grid by providing ancillary services that support the integration of energy from ...

  9. Seismic Emissions Surveys | Open Energy Information

    Open Energy Info (EERE)

    well with the location of productive wells or known geology. Authors Katz and Lewis J. Published Journal Geothermal Resources Council Transactions, 1984 DOI Not Provided...

  10. New developments in Colorado geothermal energy projects | Open...

    Open Energy Info (EERE)

    library Journal Article: New developments in Colorado geothermal energy projects Authors J. Held and F. Henderson Published Journal Geothermal Resources Council- Transactions,...

  11. Rooftop Unit Network Project - 2013 BTO Peer Review | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Rooftop Unit Suite: RTU Challenge, RTU Advanced Controls and RTU Smart Monitoring and Diagnostic System - 2013 BTO Peer Review Technical Meeting: Software Framework for Transactive ...

  12. GT Environmental Finance LLC | Open Energy Information

    Open Energy Info (EERE)

    Product: Environmental market services provider specializing in transaction and advisory services Website: www.gtenvfin.com Coordinates: 30.270601, -97.74238 Show Map Loading...

  13. Geothermal-Exploration In Arizona | Open Energy Information

    Open Energy Info (EERE)

    In Arizona Authors C. Stone and W. R. Hahman Published Journal Transactions-American Geophysical Union, 1978 DOI Not Provided Check for DOI availability: http:...

  14. This form may be submitted to the EIA by mail, fax, e-mail, or...

    U.S. Energy Information Administration (EIA) Indexed Site

    over the web using secure, encrypted processes. (It is the same method that commercial companies communicate with customers when transacting business on the web.) To use this ...

  15. This form may be submitted to the EIA by mail, fax, e-mail, or...

    U.S. Energy Information Administration (EIA) Indexed Site

    over the web using secure, encrypted processes. (It is the same method that commercial companies use to communicate with customers when transacting business on the web.) To use ...

  16. Utility Energy Service Contracts - Lessons Learned

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... reduces the perception of risk, shortens approval time, and reduces transaction costs. ... Individual fnance companies have their own experience and perception of the importance of ...

  17. USAJobs Search | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    analyst responsible for analytical work applying operations research and other scientific methods in support for BPAs transacting and credit risk management program as well...

  18. Quarterly Review

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    not include mark-to-market adjustments required by SFAS 133 or reflect the change in accounting for power "bookout" transactions made after adoption of new accounting guidance,...

  19. A restated conceptual model for the Humboldt House-Rye Patch...

    Open Energy Info (EERE)

    within the subbasin are anticipated as exploration and development proceeds. Author R.K. Ellis Published Journal Geothermal Resources Council Transactions, 2011 DOI Not Provided...

  20. South Africa-World Bank Climate Activities | Open Energy Information

    Open Energy Info (EERE)

    of power generation, whereas renewable energy power generation is a substitute for fossil fuel power generation. As a result, solar water heating transactions are not linked to...