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  1. STEM Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education STEM Education Los Alamos is committed to investing and partnering in science, technology, engineering and math (STEM) education initiatives and programs that have a...

  2. STEM Education Programs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Services STEM Education STEM Education Programs STEM Education Programs This calendar shares deadlines for Science, Technology, Engineering, and Mathematics (STEM) ...

  3. STEM Education Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM Education Programs STEM Education Programs Los Alamos National Laboratory (LANL) views its investment in STEM education as strengthening the Lab's strategic direction and developing its current and future workforce. Contacts Education Janelle Vigil-Maestas Community Relations & Partnerships (505) 665-4329 Email "We don't have to teach children to ask questions. That comes naturally. We have to not stop them." - LANL Director Charlie McMillan STEM education programs Certificate

  4. STEM Education | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Education STEM Education Women and minorities make up 70 percent of college students, but only 45 percent of undergraduate STEM degree holders. This large pool of untapped talent is a great potential source of STEM professionals. Women and minorities make up 70 percent of college students, but only 45 percent of undergraduate STEM degree holders. This large pool of untapped talent is a great potential source of STEM professionals. Science, Technology, Engineering, and Mathematics (STEM)

  5. STEM Education Program Inventory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Issue for STEM Education Program Inventory Title of Program* Requestor Contact Information First Name* Last Name* Phone Number* E-mail* Fax Number Institution Name Program Description* Issue Information Leading Organization* Location of Program / Event Program Address Program Website To select multiple options, press CTRL and click. Type of Program (if Other, enter information in the box to the right.)* Workforce Development Student Programs Public Engagement in Life Long Learning

  6. Renewable Microgrid STEM Education & Colonias Outreach Program...

    Office of Scientific and Technical Information (OSTI)

    Technical Report: Renewable Microgrid STEM Education & Colonias Outreach Program Citation Details In-Document Search Title: Renewable Microgrid STEM Education & Colonias Outreach ...

  7. Renewable Microgrid STEM Education & Colonias Outreach Program...

    Office of Scientific and Technical Information (OSTI)

    Renewable Microgrid STEM Education & Colonias Outreach Program Citation Details In-Document Search Title: Renewable Microgrid STEM Education & Colonias Outreach Program You are ...

  8. Science, Technology, Engineering and Math (STEM) Education Summit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM Education Summit STEM Education Summit The Laboratory views its investment in science, technology, engineering and math (STEM) education as strengthening the Lab's strategic...

  9. STEM Education Opportunities: Teachers

    Broader source: Energy.gov [DOE]

    Energy Literacy: Essential Principles and Fundamental Concepts for Energy Education identifies seven Essential Principles and a set of Fundamental Concepts that, if understood and applied, will...

  10. Student Educational Resources - STEM | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Student Educational Resources - STEM Student Educational Resources - STEM At Berkeley Lab, the Workforce Development & Education Office provides hands-on workshops, lab visits, outreach to the community, and mentored internships for students and faculty in order to inspire and prepare the next generation of scientists, engineers, and technicians. K-12 RESOURCES The Department of Energy Office of Energy Efficiency and Renewable Energy has a searchable library of K-12 Lesson Plans &

  11. Science, Technology, Engineering, and Math (STEM) Education Summit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM Education Summit STEM Education Summit The Laboratory views its investment in science, technology, engineering and math (STEM) education as strengthening the Lab's strategic direction and developing its current and future workforce. Contacts Education Janelle Vigil-Maestas Community Relations & Partnerships (505) 665-4329 Email Student Challenge A LANL STEM Education Summit was held in Los Alamos in April 2013. Participants at the summit reviewed the Lab's commitments in improving STEM

  12. Federal and External STEM Education Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and External STEM Education Resources Federal and External STEM Education Resources Federal and External STEM Education Resources STEM Volunteer Training Resources The Minorities in Energy Initiative launched a quarterly STEM Volunteer virtual training series on August 13, 2015. The trainings are intended to provide tips, resources and strategies for STEM professionals that want to volunteer. Role Models Matter Online Toolkit can be used to help you continue to prepare for your first role

  13. Changing the Equation in STEM Education

    Broader source: Energy.gov [DOE]

    Editor's Note: This is a cross post of an announcement that the White House featured on its blog last week. Check out the video below for Secretary Chu's thoughts on how an education in math and science helps students understand the world and deal with the pressing issues of our time. Today, President Obama announced the launch of Change the Equation, a CEO-led effort to dramatically improve education in science, technology, engineering, and math (STEM), as part of his “Educate to Innovate” campaign. Change the Equation is a non-profit organization dedicated to mobilizing the business community to improve the quality of STEM education in the United States.

  14. The SUN Project Enhances STEM Education for Native American Youth |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy The SUN Project Enhances STEM Education for Native American Youth The SUN Project Enhances STEM Education for Native American Youth April 2, 2014 - 1:25pm Addthis The SUN Project Enhances STEM Education for Native American Youth Annie Whatley Annie Whatley Deputy Director, Office of Minority Education and Community Development Last October, the Department of Energy awarded the American Indian Science and Engineering Society (AISES) a grant to implement a new program

  15. Engaging African Americans in STEM Education | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Engaging African Americans in STEM Education Engaging African Americans in STEM Education March 3, 2015 - 9:14am Addthis Engaging African Americans in STEM Education Last Wednesday, Energy Secretary Ernest Moniz sat down with Dr. Johnnetta B. Cole -- a former president of two Historically Black Colleges and Universities (Spelman College and Bennett College), and the current director of the National Museum of African Art. The two leaders talked about their experiences in higher education and the

  16. STEM Educator Training by the U.S. Naval Academy

    Broader source: Energy.gov [DOE]

    Want to improve your lessons in science, technology, engineering, and mathematics (STEM)?  Sign up for the upcoming STEM Educator Training in Project Based Learning, hosted by the Unites States...

  17. STEM Education: Preparing Students to Succeed | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Education: Preparing Students to Succeed STEM Education: Preparing Students to Succeed January 31, 2014 - 10:54am Addthis To encourage the growth of women in STEM careers, a group of girls in the eighth grade were invited to learn about career opportunities in science and engineering during the annual Introduce a Girl to Engineering Day at Argonne National Lab. | Photo courtesy of Argonne National Laboratory. To encourage the growth of women in STEM careers, a group of girls in the eighth

  18. Major New Mexico employers sign STEM education proclamation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of science, technology, engineering and math (STEM) education and workforce development. ... among a growing list of partners; sparking math and science inspiration for New Mexicans; ...

  19. Helping STEM Education Take Root: Breaking Ground on a Field...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Improving science, technology, engineering and math (STEM) education in the United States can provide a path forward for national defense, economic prosperity and international ...

  20. Julia Mundy > Fellowship - STEM Education Policy > Center Alumni...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    her Ph.D. in Spring 2014. She is now working with the Department of Education as part of the new Science, Technology, Engineering and Math (STEM) Education Policy Fellowship....

  1. Department of Education Title IX and Access to STEM Education...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... by students to change advisors, with no questions asked. ... any patterns or systemic problems that arise ... should conduct regular education and awareness programs ...

  2. Wrapping Up: Our Conversation on Increasing Diversity in STEM Education and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Workforce | Department of Energy Wrapping Up: Our Conversation on Increasing Diversity in STEM Education and the Workforce Wrapping Up: Our Conversation on Increasing Diversity in STEM Education and the Workforce March 5, 2013 - 9:43am Addthis Watch our science and tech experts answer questions and share advice on STEM Education and Careers. Dot Harris Dot Harris Director, Office of Economic Impact and Diversity Where Can I Learn More? Visit diversity.energy.gov for more on the

  3. Live Q&A: Celebrating Black History Month and STEM Education | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Q&A: Celebrating Black History Month and STEM Education Live Q&A: Celebrating Black History Month and STEM Education February 22, 2013 - 3:14pm Q&A What questions do you have about STEM education & careers? Ask our experts Addthis Join our Google+ Hangout on increasing diversity in science, technology, engineering & math disciplines. | Infographic by Sarah Gerrity. Join our Google+ Hangout on increasing diversity in science, technology, engineering & math

  4. Helping STEM Education Take Root: Breaking Ground on a Field Station in Indian Country

    Broader source: Energy.gov [DOE]

    Improving science, technology, engineering and math (STEM) education in the United States can provide a path forward for national defense, economic prosperity and international competitiveness. ...

  5. NNSA Awards $4M for STEM Education, Launches New Partnership with HBCUs |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy NNSA Awards $4M for STEM Education, Launches New Partnership with HBCUs NNSA Awards $4M for STEM Education, Launches New Partnership with HBCUs October 12, 2012 - 3:12pm Addthis The National Nuclear Security Administration (NNSA) today announced that it has awarded $4 million in grants to 22 Historically Black Colleges and Universities (HBCUs) and six Department of Energy sites in key Science, Technology, Engineering and Mathematics (STEM) areas. This funding launches

  6. Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in science, technology, engineering, and math (STEM) education initiatives and programs ... in science, technology, engineering, and math (STEM) education regionally and nationally. ...

  7. Tweet-up next Thursday! Chat with Michelle Fox about STEM in Education & the Workplace

    Broader source: Energy.gov [DOE]

    Michelle Fox will be taking questions via Twitter Thursday at 4:00pm ET about the importance of STEM education for U.S. competitiveness and economic growth.

  8. KCP hosts top STEM educators to develop curriculum | National...

    National Nuclear Security Administration (NNSA)

    skill sets needed for tomorrow's jobs in Science, Technology, Engineering and Mathematics (STEM) fields. The program is funded by a 4 million grant by the NNSA to 22 HBCUs...

  9. Shannon Greco: a self-described "STEM education zealot" | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab Shannon Greco: a self-described "STEM education zealot" The program leader in PPPL's Science Education office will be honored as a "woman of excellence" by the YWCA Princeton By Jeanne Jackson DeVoe February 1, 2016 Tweet Widget Google Plus One Share on Facebook Shannon Greco (Photo by Elle Starkman/PPPL Office of Communications) Shannon Greco Gallery: Greco and the "Orange Power" Lego robotics team she coached jump for joy during a practice

  10. Supporting STEM Education: A Q&A with the Energy Department’s Tech Transfer Coordinator

    Broader source: Energy.gov [DOE]

    Dr. Karina Edmonds -- a panelist for our upcoming STEM Google+ Hangout -- reflects on her career in STEM.

  11. stem request form | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Science Bowl Competitions Teacher Resources K-12 STEM Activities Earth Day Educational Partnerships Internship Opportunities GIFT Program STEM Education Activity Request...

  12. Department of Education Title IX and Access to STEM Education October 2012

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    for Civil Rights, Department of Education Revised October 2012 Notice  This presentation provides general information about federal civil rights laws.  Determinations of compliance depend on specific facts evaluated on a case-by-case basis.  The language used in these slides does not constitute legal advice. It is approved for general information purposes only and should not be used for other purposes. Overview of the Presentation  This presentation provides information and practical

  13. Supporting STEM Education: A Q&A with the Energy Department's...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    create meaningful privatepublic partnerships between our Labs, industry and academia. ... I look forward to speaking with students that are excited about their future in STEM and ...

  14. U.S. Energy Secretary to Discuss STEM Education, Meet with Students, During Visit to ASU

    Broader source: Energy.gov [DOE]

    WASHINGTON—Secretary of Energy, Dr. Ernest Moniz, will be in Phoenix, AZ on Thursday, December 11, to meet with STEM (Science, Technology, Engineering and Mathematics) students at Arizona State University.

  15. Energy Department Announces the SUN Project, Empowering Urban Native Youth in STEM Education

    Broader source: Energy.gov [DOE]

    The SUN Project is a new collaboration between the U.S. Department of Energy and the American Indian Science and Engineering Society to engage urban Native American youth in science, technology, engineering, and mathematics (STEM) fields.

  16. GE funds initiative to support STEM initiatives in Oklahoma ...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM Empowers OK: Initiative to enrich STEM education in Oklahoma On April 21, 2015, GE announced a grant to the state of Oklahoma to enhance STEM education initiatives. Jeff ...

  17. STEM Mentoring Café | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Education » STEM Mentoring Café STEM Mentoring Café STEM Mentoring Café in Richland, WA STEM Mentoring Café in Richland, WA Read more Overview of STEM Mentoring Cafés Overview of STEM Mentoring Cafés Read more STEM Mentoring Café Tampa, FL STEM Mentoring Café Tampa, FL Read more STEM Mentoring Café in Chicago, IL STEM Mentoring Café in Chicago, IL Read more STEM Mentoring Café in Washington, DC STEM Mentoring Café in Washington, DC Read more The critical shortage of females in

  18. STEM Mentoring- Alaska

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy's Education and Workforce Development team is hosting a science, technology, engineering, and math (STEM) Mentoring Cafe event at the Anchorage Museum at Rasmuson...

  19. STEM Resources | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM Education STEM Education Women and minorities make up 70 percent of college students, but only 45 percent of undergraduate STEM degree holders. This large pool of untapped talent is a great potential source of STEM professionals. Women and minorities make up 70 percent of college students, but only 45 percent of undergraduate STEM degree holders. This large pool of untapped talent is a great potential source of STEM professionals. Science, Technology, Engineering, and Mathematics (STEM)

  20. OVERVIEW of STEM MENTORING CAFÉ MODEL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    http://energy.gov/diversity/stem-mentoring-caf OVERVIEW of STEM MENTORING CAFÉ MODEL To help engage middle-school students with STEM (science, technology, engineering, and mathematics) professionals around the country, in 2014 the Departments of Energy and Education, along with the Association of Science-Technology Centers (ASTC), and the National Girls Collaborative Project (NGCP) started STEM Mentoring Cafés. At a Café, STEM professionals engage in quick-show-and-tell chats about their STEM

  1. Los Alamos STEM Challenge registration now open

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for students in grades 6 through 12 in Northern New Mexico to help spur their creative thinking. As part of its ongoing STEM education efforts (where STEM stands for science,...

  2. Powerpoint on STEM Programs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Powerpoint on STEM Programs Powerpoint on STEM Programs Science, Technology, Engineering, and Mathematics (STEM) skills are required to be competitive in the global race for energy development, to create and maintain a healthy economy, and foster innovation and excellence. Download a powerpoint here that provides an overview of the Department's key STEM programs. The presentation covers educational resource, teacher educational resources, internships, fellowships, mentoring, competitions, and

  3. STEM Summit | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM Education Opportunities: Grads & Researchers STEM Education Opportunities: Grads & Researchers Graduate Automotive Technology Education This DOE program helps universities sponsor student fellowships and develop graduate-level curricula, with accompanying research, in five critical technology areas: fuel cells, hybrid drive trains and control systems, lightweight materials, direct-injection engines, and advanced energy storage. In 2005, DOE began held a second competition to form

  4. Regional Education Partners

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regional Education Partners Regional Education Partners One of the Laboratory's STEM education objectives is centered on strengthening the future workforce of Northern New Mexico...

  5. STEM | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    STEM Supercomputers and New Mexico students collide in NNSA-sponsored challenge World-class science, technology, and engineering enables NNSA's missions. It's no surprise, then, that our labs and sites support STEM education initiatives ranging from preschool programs to graduate fellowships. Most recently, shining stars of New Mexico schools joined the more than... Three NNSA researchers receive President's highest early-career STEM award Yesterday Secretary of Energy Ernest Moniz hosted a

  6. STEM Education Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New Mexico Expanding Your Horizons Northern New Mexico Supercomputing Challenge PEEC Earth Day Restoration Monitoring Project Rising Stars in the Southwest Santa Fe Alliance...

  7. All kinds of jobs increasingly depend on STEM skills

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM skills Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue:May 2016 all issues All Issues » submit All kinds of jobs increasingly depend on STEM skills New Mexico's students still plagued by STEM gap December 1, 2015 Members of the STEM Action Team update the New Mexico Legislative Education Study Committee on the state of science, technology, engineering and math education in New Mexico. Members of the STEM Action Team update the New

  8. GE launches 'STEM empowers OK' initiative in Oklahoma City |...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GE Foundation donates 400,000 to enhance STEM education initiatives across Oklahoma STEM Empowers OK to sponsor week-long, GE Summer Science Academy at OSSM for Oklahoma students ...

  9. Place Based STEM: Leveraging Local Resources to Engage K-12 Teachers in Teaching Integrated STEM and for Addressing the Local STEM Pipeline

    SciTech Connect (OSTI)

    Dr. Louis Nadelson; Anne Louise Seifert; Meagan McKinney

    2014-06-01

    Business, industry, parks, nature settings, government infrastructure, and people, can be invaluable resources for connecting STEM curriculum within context which results in conditions ideal for promoting purposeful learning of authentic STEM content. Thus, community-based STEM resources offer ideal context for teaching STEM content. A benefit of focusing teacher attention on these contextual, content aligned resources is that they are in every community; making place-based STEM education a possibility, regardless of the location of STEM teaching and learning. Further, associating STEM teaching and learning with local resources addresses workforce development and the STEM pipeline by exposing students to STEM careers and applications in their local communities. The desire to align STEM teaching and learning with local STEM related resources guided the design of our week-long integrated STEM K-12 teacher professional development (PD) program, i-STEM. We have completed four years of our i-STEM PD program and have made place-based STEM a major emphasis of our curriculum. This report focuses on the data collected in the fourth year of our program. Our week-long i-STEM PD served over 425 educators last summer (2013), providing them with in depth theme-based integrated STEM short courses which were limited to an average of 15 participants and whole group plenary sessions focused around placed based integrated STEM, inquiry, engineering design, standards and practices of Common Core and 21st Century skills. This state wide PD was distributed in five Idaho community colleges and took place over two weeks. The STEM short courses included topics on engineering for sustainability, using engineering to spark interest in STEM, municipal water systems, health, agriculture, food safety, mining, forestry, energy, and others. Integral to these short courses were field trips designed to connect the K-12 educators to the resources in their local communities that could be leveraged for teaching integrated STEM and provide a relevant context for teaching STEM content. Workplace presentations made by place-based STEM experts and provided teachers field trips to place-base STEM industries and business such as manufacturing plants, waste water treatment systems, mines, nature parks, food processing plants, research, hospitals, and laboratory facilities. We researched the 425 participants’ conceptions of place-based STEM prior to and after their taking part in the summer institutes, which included fieldtrips. Our findings revealed substantial increase in our participants’ knowledge, interest, and plans to use place-based resources for teaching integrated STEM. We detail the data analysis and provide a theoretical foundation and justification for the importance of place-based STEM to address the STEM pipeline for the future workforce.

  10. Green Investment Bank | Open Energy Information

    Open Energy Info (EERE)

    Name: Green Investment Bank Place: United Kingdom Product: UK-based investment bank that will focus on clean energy investment. References: Green Investment Bank1 This article...

  11. Carbon Bank Ireland | Open Energy Information

    Open Energy Info (EERE)

    Ireland Jump to: navigation, search Name: Carbon Bank Ireland Place: Nevada Zip: 89411 Product: Investment bank focused on CDM projects. References: Carbon Bank Ireland1 This...

  12. Upholding Dr. King's Dream and Inspiring the Next Generation Through STEM

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education | Department of Energy Upholding Dr. King's Dream and Inspiring the Next Generation Through STEM Education Upholding Dr. King's Dream and Inspiring the Next Generation Through STEM Education January 27, 2015 - 12:56pm Addthis Upholding Dr. King’s Dream and Inspiring the Next Generation Through STEM Education Joshua Sneideman Joshua Sneideman Albert Einstein Distinguished Educator Fellow According to the Reverend Dr. Martin Luther King, Jr., "The function of education is

  13. Second Annual Interagency STEM Volunteer Fair

    Broader source: Energy.gov [DOE]

    The Department of Energy and the Office of Personnel Management (OPM) are hosting the Second Annual Interagency STEM Volunteer Fair, aiming to match the needs of the STEM and educational community in the Washington, D.C., area with our federal workers who are seeking volunteer opportunities. The event is open to all federal workers and contractors.

  14. STEM Volunteer Training: Crafting your STEM Message

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Does your STEM Story make sense? Practice Your STEM Story Instructions: Spend 5 minutes ... the audience's lives and communities. * Background on your academic and career journey. ...

  15. STEM Mentoring Café- Engaging Young Women in an Authentic Mentoring...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Mentoring Caf- Engaging Young Women in an Authentic Mentoring Experience Melinda Higgins Albert Einstein Distinguished Educator Fellow, NASA Office of Education, ...

  16. Webinar: Energy Is Everywhere! STEM Mentoring

    Broader source: Energy.gov [DOE]

    As part of the “Energy Is Everywhere” webinar series and in honor of Mentoring Month, the U.S. Departments of Housing & Urban Development, Energy, and Education are pleased to offer a STEM...

  17. STEM and Equal Pay | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... women drive innovation in the clean energy economy. And our Minorities in Energy Initiative, modeled on C3E, seeks to fully engage minorities in STEM education, energy economic ...

  18. STEm Minority Graduate Program

    SciTech Connect (OSTI)

    Kaen E. Nicholas

    2012-09-20

    ABSTRACT The state of science, technology, engineering and math (STEM) education in the United States has seen some unfavorable assessments over the past decade. In early February, 2010 the House of Representatives heard testimony on undergraduate and graduate education. The message from the panel, which included experts from academia, STEM-based industries, and the National Science Foundation (NSF) was dire and required an urgent response. The experts along with the committee???¢????????s chairperson, U. S. Representative Daniel Lipinski (D-IL) cited that the complexity of Science, Technology, Engineering, and Mathematics applications and coursework and the methodology utilized to teach these subjects are forcing students out of these disciplines. As the National Academies described in its 2007 report Rising Above the Gathering Storm, successful STEM education is not just an academic pursuit???¢????????it???¢????????s a necessity for competing in the knowledge-based economy that the United States had a key role in creating. The potential for action is being made available again as the America COMPETES Act of 2007 is up for reauthorization. Its initial focus was on STEM education at the K-12 levels, but efforts at the undergraduate and graduate levels are needed to retain students to fill the jobs left vacant as baby boomers retire. The Educational Advancement Alliance, Inc. (EAA) has for two decades created programs that have not only addressed the issues of ensuring that students are aptly prepared for college but have focused its efforts over the past decade on increasing the number of students who pursue degrees in STEM disciplines. For the EAA, the introduction of the wonders of science begins at the elementary and middle school level via the Learning Lab, a state-of-the-art mobile science laboratory that visits students in grades 4-6 at the various schools throughout Philadelphia and The Math/Tech Academy which meets on Saturdays for students in grades 5-7. For the past two years the EAA has assisted college graduates in their quest to attain advanced degrees in STEM by providing fellowships. The EAA continued this effort by recruiting and providing fellowships to students who aspired to continue their education at the graduate level. The fellowships provided funding for tuition, fees, books, technology, and stipends to assist with room, board, and living expenses during the academic year and salary, transportation, and living expenses to those students who secured internships with the Department of Energy. Additionally the EAA designed and implemented needed support systems to ensure successful completion of the Masters degree programs, including but not limited to membership in professional associations, attendance at industry and academic conferences, and professional development workshops, and tutorial assistance if needed. This program assisted over 80 students directly and society-at-large by helping to educate and develop future physicists, engineers, biostatisticians, and researchers who will have the necessary skillsets to fill the increasing numbers of positions that require such expertise.

  19. K-12 Education Resources - SRSCRO

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    K-12 Education Resources Science, Technology, Engineering and Mathematics (STEM) skills ... Ruth Patrick Science Education Center Experience the power of science and mathematics ...

  20. Volunteer Needs - First Annual STEM Volunteer Fair February 2014 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Volunteer Needs - First Annual STEM Volunteer Fair February 2014 Volunteer Needs - First Annual STEM Volunteer Fair February 2014 The Department of Energy hosted the First Annual Federal STEM Volunteer Fair, aiming to match the needs of the STEM and educational community in the Washington, D.C., area with our federal workers who are seeking volunteer opportunities. The event was open to all federal workers and contractors. At this event, federal workers from all agencies

  1. Minority Banks | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Banks Minority Banks Our Bank Deposit Financial Assistance Program was developed for the purpose of strengthening and expanding the Nation's minority and women-owned small business enterprises. In order to classify as "minority" the institution's majority ownership must include African Americans, Hispanic Americans, Asian Americans, American Indians, Eskimos, Aleuts, and women. The minority institution must certify minority ownership with the Department of the Treasury and appear on

  2. SC11 Education Program Applications due July 31

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Mathematics (STEM) disciplines, as well as to undergraduate and graduate students considering careers teaching in STEM disciplines. The program also assists educators...

  3. Energy Education Resources in Spanish | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... La comunidad hispana en las materias STEM (101714) Conocimiento de Energa y la educacin STEM (6614) More Documents & Publications Energy Education Resources in Spanish ...

  4. Stem Mentoring Cafe- Albuquerque

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy is hosting a STEM Mentoring Cafe to engage middle school students in STEM and their teachers with federal STEM professionals, through speed mentoring sessions and a commitment to ongoing mentoring from federal employees.

  5. Stem Mentoring Cafe- Houston

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy is hosting a STEM Mentoring Cafe to engage middle school students in STEM and their teachers with federal STEM professionals, through speed mentoring sessions and a commitment to ongoing mentoring from federal employees.

  6. STEM Career Information Seminar

    Broader source: Energy.gov [DOE]

    This event will expose high school students to STEM professionals and STEM careers at the Department of Energy. We'll also cover the federal hiring process, internships, and information on getting involved in Department of Energy STEM programs.

  7. LANL STEM Education Request Form

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Select Start Date Select End Date Submit Reset

  8. LAYCCA STEM Fair 2014 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    LAYCCA STEM Fair 2014 LAYCCA STEM Fair 2014

  9. Central Bank of India | Open Energy Information

    Open Energy Info (EERE)

    India Jump to: navigation, search Name: Central Bank of India Place: DELHI, Delhi (NCT), India Zip: 110002 Product: Retail bank closely conencted with social development through...

  10. European Investment Bank | Open Energy Information

    Open Energy Info (EERE)

    Logo: European Investment Bank Name: European Investment Bank Address: 98-100, boulevard Konrad Adenauer L-2950 Place: Luxembourg Product: Microfinance, Loans, Venture Capital...

  11. UCEAO: Energy Knowledge Bank | Open Energy Information

    Open Energy Info (EERE)

    UCEAO: Energy Knowledge Bank Jump to: navigation, search Name: UCEAO: Energy Knowledge Bank Place: Ohio Website: knowledgebank.uso.edu References: University Clean Energy Alliance...

  12. The Global Carbon Bank | Open Energy Information

    Open Energy Info (EERE)

    Global Carbon Bank Jump to: navigation, search Name: The Global Carbon Bank Place: Houston, Texas Zip: 77025 Sector: Carbon, Services Product: Houston-based provider of advisory...

  13. #WomenInSTEM: Making a Cleaner Future | Department of Energy

    Energy Savers [EERE]

    #WomenInSTEM: Making a Cleaner Future #WomenInSTEM: Making a Cleaner Future Addthis Duration 1:44 Topic Energy Sector Jobs Solar Wind Science Education

  14. STEM Café Hits the Midwest | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Café Hits the Midwest STEM Café Hits the Midwest July 27, 2015 - 2:38pm Addthis Aerial view of STEM Mentoring Café table in Chicago: Photo Courtesy of Argonne National Aerial view of STEM Mentoring Café table in Chicago: Photo Courtesy of Argonne National Erin Twamley Project and Web Manager, Education & Workforce Development In the heart of the Midwest, the Museum of Science and Industry Chicago is helping to engage STEM professionals and middle school students. As part of the

  15. About Educational Programs | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Educational Programs' vision is to enrich science, technology, engineering and mathematics (STEM) education through programs that advance Argonne's strategic energy, environment, ...

  16. Reports and Publications on Women and Girls in STEM | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Reports and Publications on Women and Girls in STEM Reports and Publications on Women and Girls in STEM As the United States Department of Commerce says, "Our science, technology, engineering and math (STEM) workforce is crucial to America's innovative capacity and global competitiveness. Yet women are vastly underrepresented in STEM jobs and among STEM degree holders despite making up nearly half of the U.S. workforce and half of the college-educated workforce. That leaves an untapped

  17. Rotatable stem and lock

    DOE Patents [OSTI]

    Deveney, J.E.; Sanderson, S.N.

    1981-10-27

    A valve stem and lock is disclosed which includes a housing surrounding a valve stem, a solenoid affixed to an interior wall of the housing, an armature affixed to the valve stem and a locking device for coupling the armature to the housing body. When the solenoid is energized, the solenoid moves away from the housing body, permitting rotation of the valve stem.

  18. STEM: Volunteer Training Engaging Middle School Students

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM: Volunteer Training Engaging Middle School Students August 13, 2015 Erin Twamley Education Project Manager Department of Energy Nimisha Ghosh Roy Network Manager National Girls Collaborative Project Rabiah Mayas, Ph.D. Director of Science and Integrated Strategies Museum of Science and Industry Chicago 2 Agenda You are on mute! Use your webinar bar to fill out poll, send a chat or send in a question. Please tell us via chat if you cannot see or hear. Overview of STEM Training Key Outcomes

  19. Kevin Banks | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kevin Banks By Justin H.S. Breaux * October 6, 2014 Tweet EmailPrint Kevin Banks is a freshman at the Milwaukee School of Engineering, where he studies biomedical engineering. As an intern within the Chicago Scholars Argonne Future Research Program, Kevin conducted research this summer in Argonne's Energy Systems division. His research seeks to increase energy efficiency by reducing friction and wear on machines using engine oils. "What I liked most about my internship experience was

  20. GE funds initiative to support STEM initiatives in Oklahoma | GE Global

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research STEM Empowers OK: Initiative to enrich STEM education in Oklahoma Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to share on LinkedIn (Opens in new window) Click to share on Tumblr (Opens in new window) STEM Empowers OK: Initiative to enrich STEM education in Oklahoma On April 21, 2015, GE announced a grant to the state of Oklahoma to enhance STEM education initiatives. Jeff Immelt, GE's

  1. STEM Volunteer Training: Crafting your STEM Message

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Crafting your STEM Message November 12, 2015 Rabiah Mayas, Ph.D. Director of Science and Integrated Strategies Museum of Science and Industry Chicago Melinda Higgins Science and Technology Policy Fellow Department of Energy Megan Davis Program Manager Techbridge #WomenInSTEM #STEMCafes 2 Training Agenda You are on mute! Use your webinar bar to send a chat or send in a question. Please tell us via chat if you cannot see or hear. Welcome and Introduction (DOE) Sharing Successful STEM Interaction

  2. Native American Students in STEM Fields: A Critical Need for our Country

    Broader source: Energy.gov [DOE]

    The Office of Economic Impact and Diversity's Dot Harris recently met with youth from Tribal Nations around the U.S. to discuss the benefits of STEM education.

  3. Republic of Macedonia-World Bank Climate Projects | Open Energy...

    Open Energy Info (EERE)

    World Bank Climate Projects Jump to: navigation, search Name Republic of Macedonia-World Bank Climate Projects AgencyCompany Organization World Bank Sector Energy, Land Focus...

  4. Gabon-World Bank Climate Activities | Open Energy Information

    Open Energy Info (EERE)

    World Bank Climate Activities Jump to: navigation, search Name Gabon-World Bank Climate Activities AgencyCompany Organization World Bank Sector Land Focus Area Forestry Topics...

  5. Ukraine-World Bank Climate Projects | Open Energy Information

    Open Energy Info (EERE)

    World Bank Climate Projects Jump to: navigation, search Name Ukraine-World Bank Climate Projects AgencyCompany Organization World Bank Sector Energy Focus Area Energy Efficiency...

  6. Women in STEM

    Broader source: Energy.gov [DOE]

    A page showcasing the great contributions of women in the energy sector and encouraging girls to continue studying STEM.

  7. Education partnerships help students succeed

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    science, technology, engineering and math (STEM) education through faculty and ... School, a participant in the Laboratory's Math and Science Academy, sixth-grade Santa ...

  8. Stem Mentoring Cafe- Denver

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy is hosting a STEM Mentoring Cafe in Denver, Colorado, to engage middle school students in STEM and their teachers with federal STEM professionals, through speed mentoring sessions and a commitment to ongoing mentoring from federal employees.

  9. Select Bank Plc | Open Energy Information

    Open Energy Info (EERE)

    Bank Plc Jump to: navigation, search Name: Select Bank Plc Place: Mayfair, England, United Kingdom Zip: W1J 8LQ Sector: Renewable Energy Product: England-based firm that promotes...

  10. EA-342 Royal Bank of Canada | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon EA-342 Royal Bank of Canada More Documents & Publications EA-342-A Royal Bank of Canada EA-330 The Royal Bank of Scotland plc EA-330-A The Royal Bank of Scotland plc

  11. STEM Volunteer Training: Crafting Your STEM Story

    Broader source: Energy.gov [DOE]

    Join us for the STEM volunteer training series hosted in partnership by Department of Energy with the National Girls Collaborative Project, TechBridge and the Museum of Science and Industry in...

  12. Join the Call: One Million Hours of STEM Volunteer Service | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Call: One Million Hours of STEM Volunteer Service Join the Call: One Million Hours of STEM Volunteer Service June 30, 2015 - 10:19am Addthis Join the Call: One Million Hours of STEM Volunteer Service America's ability to meet the demands of its energy future depends on having a trained, dedicated science, technology, engineering, and mathematics (STEM) workforce. To answer this call, the Energy Department has an obligation to do all that is possible to attract, engage, educate, and

  13. Y-12 recognized for work with STEM group | National Nuclear Security

    National Nuclear Security Administration (NNSA)

    Administration recognized for work with STEM group Tuesday, October 21, 2014 - 9:31am Y-12 has been recognized by the Federal Laboratory Consortium for its outstanding work in support of science, technology, engineering, and math education. The FLC Southeast Region selected Y-12 for the 2014 Outstanding Accomplishment in STEM Education Support award for its partnership with the Young Innovators' Society STEM league. Y-12 assembled a project team of scientists and experts from Y-12, Oak Ridge

  14. #WomenInSTEM: Using Science and Math to Power the Globe | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Using Science and Math to Power the Globe #WomenInSTEM: Using Science and Math to Power the Globe May 27, 2014 - 5:05pm Addthis Dr. Rhonda Jordan is an energy specialist at World Bank and our latest #WomenInSTEM video profile. | Video by Matty Greene. Erin R. Pierce Erin R. Pierce Former Digital Communications Specialist, Office of Public Affairs Matty Greene Matty Greene Former Videographer Earlier this year we launched #WomenInSTEM, a video series highlighting the accomplishments of

  15. STEM Challenge Winners

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2016 all issues All Issues submit STEM Challenge Winners Students celebrate the Lab's past and future June 1, 2013 Students from Valarde Middle School won the video competition...

  16. STEM Diversity Career Expo

    Broader source: Energy.gov [DOE]

    Career Expo for entry-level and professional job applicants in all STEM career disciplines including people with disabilities and wounded warriors. 

  17. iSTEM 2011

    ScienceCinema (OSTI)

    None

    2013-05-28

    Idaho National Laboratory leads the Idaho Science, Technology, Engineering and Math network. This video is an overview of the iSTEM program

  18. Investing in Minority Banks | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Investing in Minority Banks Investing in Minority Banks Our Bank Deposit Financial Assistance Program was developed for the purpose of strengthening and expanding the Nation's minority and women-owned small business enterprises. In order to classify as "minority" the institution's majority ownership must include African Americans, Hispanic Americans, Asian Americans, American Indians, Eskimos, Aleuts, and women. The minority institution must certify minority ownership with the

  19. Bank of America | Open Energy Information

    Open Energy Info (EERE)

    America Jump to: navigation, search Name: Bank of America Place: Charlotte, NC Zip: 28202 Website: www.bankofamerica.com References: NREL & Industry: National Account Companies1...

  20. Intern Spotlight: Kevin Banks | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kevin Banks is a freshman at the Milwaukee School of Engineering, where he studies biomedical engineering. As an intern within the Chicago Scholars Argonne Future Research...

  1. The World Bank - Transport | Open Energy Information

    Open Energy Info (EERE)

    provides relevant information about transport, focusing on The World Bank Transport Strategy - Safe, Clean and Affordable - Transport for Development. The website includes...

  2. Building Green in Greensburg: Greensburg State Bank

    Broader source: Energy.gov [DOE]

    This poster highlights energy efficiency, renewable energy, and sustainable features of the high-performing Greensburg State Bank building in Greensburg, Kansas.

  3. Building Green in Greensburg: Centera Bank

    Broader source: Energy.gov [DOE]

    This poster highlights energy efficiency, renewable energy, and sustainable features of the high-performing Centera Bank building in Greensburg, Kansas.

  4. Building Green in Greensburg: The Peoples Bank

    Broader source: Energy.gov [DOE]

    This poster highlights energy efficiency, renewable energy, and sustainable features of the high-performing Peoples Bank building in Greensburg, Kansas.

  5. NY Green Bank | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    sector to address and alleviate market and financial barriers preventing a thriving clean energy marketplace. NY Green Bank does not accept deposits or offer retail loans, and...

  6. STEM Mentoring Café- Engaging Young Women in an Authentic Mentoring Experience

    Broader source: Energy.gov [DOE]

    The STEM Mentoring Café, hosted by the U.S. Department of Education, took place on May 19, 2014 from 4:30pm-6:00pm. Thirty female STEM professionals from 16 different government agencies arrived with their tools of their trade, ready to interact with eighteen teachers and thirty-eight 5-8 grade students to share their passion for their STEM careers. The participants assimilated quickly to the speed-dating format, with STEM professionals moving from table to table, enabling students and teachers to ask questions and learn about STEM professions during each roundtable discussion.

  7. GE launches 'STEM empowers OK' initiative in Oklahoma City | GE Global

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research GE, OCAST and OSSM Partner to Launch "STEM Empowers OK" Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to share on LinkedIn (Opens in new window) Click to share on Tumblr (Opens in new window) GE, OCAST and OSSM Partner to Launch "STEM Empowers OK" stem empowers ok GE Foundation donates $400,000 to enhance STEM education initiatives across Oklahoma STEM Empowers OK to

  8. Launching STEM Careers through Exposure and Exploration | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Launching STEM Careers through Exposure and Exploration Launching STEM Careers through Exposure and Exploration June 19, 2015 - 2:19pm Addthis Girls from the Tampa Public Housing Authority participated in a hands-on activity at the Museum of Science and Industry. | Energy Department photo. Girls from the Tampa Public Housing Authority participated in a hands-on activity at the Museum of Science and Industry. | Energy Department photo. Erin Twamley Project and Web Manager, Education

  9. Helping STEM Take Root: EM Tribal Partnership Looks To the Future of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Science Education | Department of Energy Helping STEM Take Root: EM Tribal Partnership Looks To the Future of Science Education Helping STEM Take Root: EM Tribal Partnership Looks To the Future of Science Education November 1, 2012 - 12:00pm Addthis Umatilla Tribes Department of Science and Engineering Director Stuart Harris, far right, explains the purpose of the Tribes’ greenhouses to Senior Advisor for Environmental Management David Huizenga, center, and Richland Operations Office

  10. Making STEM Personal

    Broader source: Energy.gov [DOE]

    Occupations in science, technology, engineering, and mathematics (STEM) are among the fastest growing fields, offering well-paying opportunities to better explore, understand, and improve the world. To celebrate Women’s History Month, DOE recently introduced an online Women @ Energy series that profiles DOE women involved in STEM., Included in the Women @ Energy series are OE’s Assistant Secretary Patricia Hoffman and Carol Hawk who manages the Cybersecurity for Energy Delivery Systems Program.

  11. RESIDENTIAL NETWORK MEMBERS UNITE TO FORM GREEN BANK NETWORK | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy RESIDENTIAL NETWORK MEMBERS UNITE TO FORM GREEN BANK NETWORK RESIDENTIAL NETWORK MEMBERS UNITE TO FORM GREEN BANK NETWORK The NY Green Bank logo. Residential Network members Connecticut Green Bank and NY Green Bank, a division of Residential Network member New York State Energy Research and Development Authority, have helped launch the Green Bank Network, a new international organization focused on collaborating to scale up private financing to meet the challenge of climate change.

  12. PNC Bank Equipment Finance and Energy Group | Open Energy Information

    Open Energy Info (EERE)

    to: navigation, search Name: PNC Bank - Equipment Finance and Energy Group Place: Valencia, California Zip: 91355 Product: Energy and Equipment Finance arm of PNC Bank...

  13. India-World Bank Climate Projects | Open Energy Information

    Open Energy Info (EERE)

    Name India-World Bank Climate Projects AgencyCompany Organization World Bank Sector Energy, Land Focus Area Energy Efficiency, Renewable Energy Topics Background analysis...

  14. Philippines-World Bank Climate Projects | Open Energy Information

    Open Energy Info (EERE)

    Philippines-World Bank Climate Projects AgencyCompany Organization World Bank Sector Energy, Land Focus Area Renewable Energy, Energy Efficiency, Geothermal Topics Background...

  15. World Bank-Climate Change Knowledge Portal | Open Energy Information

    Open Energy Info (EERE)

    Climate Change Knowledge Portal Jump to: navigation, search Logo: World Bank-Climate Change Knowledge Portal Name World Bank-Climate Change Knowledge Portal AgencyCompany...

  16. Global Climate Change: Risk to Bank Loans | Open Energy Information

    Open Energy Info (EERE)

    Risk to Bank Loans Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Global Climate Change: Risk to Bank Loans AgencyCompany Organization: United Nations...

  17. Colorado State Bank and Trust | Open Energy Information

    Open Energy Info (EERE)

    Bank and Trust Jump to: navigation, search Name: Colorado State Bank and Trust Place: Denver, Colorado Zip: 80202 Sector: Renewable Energy Product: Leasing and lending for...

  18. LNJ Bhilwara Group Glitnir Bank JV | Open Energy Information

    Open Energy Info (EERE)

    - Glitnir Bank JV Place: Noida, India Zip: 201 301 Sector: Geothermal energy Product: Joint venture established by LNJ Bhilwara Group and Glitnir Bank, for the development of...

  19. RESIDENTIAL NETWORK MEMBERS UNITE TO FORM GREEN BANK NETWORK...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Residential Network members Connecticut Green Bank and NY Green Bank, a division of Residential Network member New York State Energy Research and Development Authority, have helped ...

  20. Georgia-World Bank Climate Projects | Open Energy Information

    Open Energy Info (EERE)

    Projects Jump to: navigation, search Name Georgia-World Bank Climate Projects AgencyCompany Organization World Bank Focus Area Renewable Energy, Hydro Topics Background analysis...

  1. STEM Mentoring Caf | Department of Energy

    Office of Environmental Management (EM)

    STEM Mentoring Caf. This program is an interagency effort to engage middle school students in STEM and their teachers with federal STEM professionals, through speed mentoring...

  2. Regional Education Partners

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regional Education Partners Regional Education Partners One of the Laboratory's STEM education objectives is centered on strengthening the future workforce of Northern New Mexico and LANL through effective partnerships with regional secondary and higher education organizations, businesses and industry. Contact Executive Office Director Kathy Keith Community Relations & Partnerships (505) 665-4400 Email Regional Partners Charlie McMillan talking with Rick Ulibarri and Dr. Fries, President of

  3. Valve stem and packing assembly

    DOE Patents [OSTI]

    Wordin, J.J.

    1991-09-03

    A valve stem and packing assembly is provided in which a rotatable valve stem includes a first tractrix surface for sliding contact with a stem packing and also includes a second tractrix surface for sliding contact with a bonnet. Force is applied by means of a spring, gland flange, and gland on the stem packing so the stem packing seals to the valve stem and bonnet. This configuration serves to create and maintain a reliable seal between the stem packing and the valve stem. The bonnet includes a second complementary tractrix surface for contacting the second sliding tractrix surface, the combination serving as a journal bearing for the entire valve stem and packing assembly. The journal bearing so configured is known as a Schiele's pivot. The Schiele's pivot also serves to maintain proper alignment of the valve stem with respect to the bonnet. Vertical wear between the surfaces of the Schiele's pivot is uniform at all points of contact between the second sliding tractrix surface and the second complementary tractrix surface of a bonnet. The valve stem is connected to a valve plug by means of a slip joint. The valve is opened and closed by rotating the valve stem. The slip joint compensates for wear on the Schiele's pivot and on the valve plug. A ledge is provided on the valve bonnet for the retaining nut to bear against. The ledge prevents over tightening of the retaining nut and the resulting excessive friction between stem and stem packing. 2 figures.

  4. Valve stem and packing assembly

    DOE Patents [OSTI]

    Wordin, John J.

    1991-01-01

    A valve stem and packing assembly is provided in which a rotatable valve stem includes a first tractrix surface for sliding contact with a stem packing and also includes a second tractrix surface for sliding contact with a bonnet. Force is applied by means of a spring, gland flange, and gland on the stem packing so the stem packing seals to the valve stem and bonnet. This configuration serves to create and maintain a reliable seal between the stem packing and the valve stem. The bonnet includes a second complementary tractrix surface for contacting the second sliding tractrix surface, the combination serving as a journal bearing for the entire valve stem and packing assembly. The journal bearing so configured is known as a Schiele's pivot. The Schiele's pivot also serves to maintain proper alignment of the valve stem with respect to the bonnet. Vertical wear between the surfaces of the Schiele's pivot is uniform at all points of contact between the second sliding tractrix surface and the second complementary tractrix surface of a bonnet. The valve stem is connected to a valve plug by means of a slip joint. The valve is opened and closed by rotating the valve stem. The slip joint compensates for wear on the Schiele's pivot and on the valve plug. A ledge is provided on the valve bonnet for the retaining nut to bear against. The ledge prevents overtightening of the retaining nut and the resulting excessive friction between stem and stem packing.

  5. EERE: Education Calendar | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EERE: Education Calendar EERE: Education Calendar April 2016 < prev next > Sun Mon Tue Wed Thu Fri Sat 27 28 29 30 31 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 STEM Volunteer ...

  6. Join the STEM and Mentoring Interagency Open House Friday, January 18, in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Washington DC | Department of Energy STEM and Mentoring Interagency Open House Friday, January 18, in Washington DC Join the STEM and Mentoring Interagency Open House Friday, January 18, in Washington DC January 15, 2013 - 1:51pm Addthis Join the STEM and Mentoring Interagency Open House Friday, January 18, in Washington DC You're Invited: In honor of National Mentoring Month and the 57th Presidential Inauguration, the Departments of Energy, Transportation, Labor, Education, National Science

  7. Employees give to local food bank

    Broader source: Energy.gov [DOE]

    Employees in DOE's Oak Ridge Office of EM donated 3,209 pounds of food to the Second Harvest Food Bank of East Tennessee. The donation was part of the national Feds Feed Families campaign.

  8. The DOE/DOD Environmental Data Bank

    SciTech Connect (OSTI)

    C de Baca, J.E.

    1996-07-01

    The DOE/DOD Environmental Data Bank was established in 1959 as a central location for storing weapons and equipment environments information from a variety of DOE, DOD, and industrial sources and continues to be maintained by Sandia National Laboratories. The Environmental Data Bank contains approximately 2,900 documents regarding normal and abnormal environments that describe the handling, storage, transportation, use, and general phases, which occur during the life of a weapon system. The Environmental Data Bank contains a vast assortment of resources that document crash, fire, and chemical environments resulting from aircraft, rail, ship, and truck accidents, as well as crash and thermal tests conducted on shipping containers. Also included are studies on the hazards of exposure to liquid natural gas fireballs, chemical fireballs, and hydrogen fireballs. This paper describes the DOE/DOD Environmental Data Bank system, its structure, data sources, and usage, with particular emphasis on its use for safety assessments at Sandia National Laboratories.

  9. STEM Education Opportunities: Grads & Researchers | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Hydro Fellowship Program Funded by a DOE award of 1 million, the Hydro Research Foundation's competitive Hydro Fellowship Program will award two-year fellowships for up to 26 ...

  10. STEM Education Programs | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    to 9:00PM EST Physics of Accelerators and Related Technology for International Students (PARTI). 5:45PM EST 16 17 18 19 20 21 22 Internships for Physics Majors 4:30PM to...

  11. STEM Education Programs | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 2013 < prev next > Sun Mon Tue Wed Thu Fri Sat 30 31 1 2 3 4 5 Internships for Physics Majors 4:30PM to 10:45PM EDT Lee Teng Undergraduate Internship in...

  12. STEM Education Programs | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    < prev next > Sun Mon Tue Wed Thu Fri Sat 28 29 30 31 1 2 3 Internships for Physics Majors 4:30PM to 10:45PM EDT Lee Teng Undergraduate Internship in Accelerator Science...

  13. STEM Education Programs | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    < prev next > Sun Mon Tue Wed Thu Fri Sat 26 27 28 29 30 31 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 1 2 3 4 5 6...

  14. STEM Education Programs | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    < prev next > Sun Mon Tue Wed Thu Fri Sat 29 30 31 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 1...

  15. STEM Education Programs | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    < prev next > Sun Mon Tue Wed Thu Fri Sat 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 1 2 3 4...

  16. Energy Department and the NSTA Launch America's Home Energy Education...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Administered by NSTA for the Energy Department, America's Home Energy Education Challenge inspires student interest in science, technology, engineering and math (STEM), while ...

  17. Interested in STEM? Join us for a Tweet-up This Thursday at 4pm ET |

    Broader source: Energy.gov (indexed) [DOE]

    Department of Energy Join Michelle Fox on Twitter this Thursday at 4:00pm for a Tweet-up about STEM investments in education and the workforce. Join Michelle Fox on Twitter this Thursday at 4:00pm for a Tweet-up about STEM investments in education and the workforce. Amanda Scott Amanda Scott Former Managing Editor, Energy.gov How can I participate? Send us your questions via Twitter (@ENERGY) using #STEM. Email us your questions at newmedia@hq.doe.gov. Join us on Thursday, May 10 at 4:00pm

  18. STEM | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The acronym for the study of science technology, engineering and mathematics, identified ... Science, Technology, Engineering, and Mathematics (STEM) on March 18. They talked to ...

  19. World Bank Good Practice Guidelines: Financial Analysis of Revenue...

    Open Energy Info (EERE)

    AgencyCompany Organization: World Bank Topics: Finance Resource Type: Guidemanual Website: siteresources.worldbank.orgINTRANETFINANCIALMGMTResourcesFMB-Notes...

  20. Banking on Solar: An Analysis of Banking Opportunities in the U.S. Distributed Photovoltaic Market

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Banking on Solar: An Analysis of Banking Opportunities in the U.S. Distributed Photovoltaic Market David Feldman and Travis Lowder National Renewable Energy Laboratory Technical Report NREL/TP-6A20-62605 November 2014 NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy Operated by the Alliance for Sustainable Energy, LLC This report is available at no cost from the National Renewable Energy Laboratory (NREL) at

  1. STEM Volunteer Training Materials | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Volunteer Training Materials STEM Volunteer Training Materials STEM Volunteer Training Materials The STEM Volunteer Virtual Training series was launched in August 2015. The series is a quarterly virtual training to provide tips, information, and resources for federal STEM professionals interested in volunteering. This page has presentation and videos from the training series. For more information or questions please email: STEMED@energy.gov. File STEM Volunteer Training - Engaging Middle

  2. Women in STEM -- Why We Need All Hands on Deck

    ScienceCinema (OSTI)

    Wall; Carter

    2014-06-04

    Carter Wall developed an interest in science at an early age yet struggled to find examples of women scientists and engineers beyond historical figures, like Marie Curie. A lack of relatable role-models didn't stop Carter from pursuing an undergraduate education and career rooted in STEM -- shorthand for science, technology, engineering and mathematics fields. Now, she plays a key role at one of largest solar developers in the Northeast. This is the first in the Energy Department's #WomenInStem video series. At the Energy Department, we're committed to supporting a diverse talent pool of STEM innovators ready to address the challenges and opportunities of our growing clean energy economy

  3. Minority Educational Institution Student Partnership Program (MEISPP) |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Development » Minority Educational Institution Student Partnership Program (MEISPP) Minority Educational Institution Student Partnership Program (MEISPP) Our Minority Educational Institution Student Partnership Program (MEISPP) offers talented undergraduate and graduate students summer internship positions with the Department of Energy and our National Laboratories, with the goal of reaching underrepresented students in STEM fields, such as women and girls. Positions

  4. EA-342-A Royal Bank of Canada | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -A Royal Bank of Canada EA-342-A Royal Bank of Canada Order authorizing Royal Bank of Canada to export electric energy to Canada. PDF icon EA-342-A RBC (CN).pdf More Documents & Publications EA-328-A RBC Energy Services LP Application to Export Electric Energy OE Docket No. EA-328-A RBC Energy Services LP EA-97-D Portland General Electric Company

  5. IADG Energy Bank Revolving Loan Program | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    Authority and Iowa Area Development Group Website http:www.iadg.comservicesfinancial-assistanceiadg-energy-bank.aspx Funding Source American Recovery and...

  6. World Bank Climate Innovation Centers | Open Energy Information

    Open Energy Info (EERE)

    America and the Caribbean) for this property. References Climate Innovation Center Business Plans1 InfoDev2 World Bank Climate Innovation Centers Screenshot "The CIC works...

  7. Making Development Climate Resilient: A World Bank Strategy for...

    Open Energy Info (EERE)

    Development Climate Resilient: A World Bank Strategy for Sub-Saharan Africa Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Making Development Climate Resilient: A World...

  8. Red Bank, New Jersey: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    (Redirected from Red Bank, NJ) Jump to: navigation, search Equivalent URI DBpedia Coordinates 40.3470543, -74.0643065 Show Map Loading map... "minzoom":false,"mappingservice":...

  9. Ex-Im Bank Environmental Export Finance Program | Open Energy...

    Open Energy Info (EERE)

    Environmental Export Financing Webpage 1 "Ex-Im Bank's financing helps mitigate risk for U.S. environmental companies and also offers competitive financing terms to...

  10. Exploring STEM in Florida | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Exploring STEM in Florida Exploring STEM in Florida August 24, 2015 - 10:18am Addthis A Mentoring Table at the West Palm Beach STEM Cafe A Mentoring Table at the West Palm Beach STEM Cafe Crossposted from the South Florida Science Center and Aquarium Blog on 8.19.2015 Combine an awesome group of students, scientists, coffee and plenty of inspiration and you'll have the necessary ingredients that made our inaugural STEM Mentoring Café a great success! The STEM Mentoring Café is run in

  11. EA-330 The Royal Bank of Scotland plc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The Royal Bank of Scotland plc EA-330 The Royal Bank of Scotland plc Order authorizing The Royal Bank of Scotland plc to export electric energy to Canada PDF icon EA-330 The Royal ...

  12. EA-330-A The Royal Bank of Scotland plc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -A The Royal Bank of Scotland plc EA-330-A The Royal Bank of Scotland plc Order authorizing The Royal Bank of Scotland plc to export electric energy to Canada PDF icon EA-330-A The ...

  13. EA-331-A The Royal Bank of Scotland plc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EA-331-A The Royal Bank of Scotland plc Order authorizing The Royal Bank of Scotland plc to export eelctric energy to Mexico PDF icon EA-331-A The Royal Bank of Scotland plc More ...

  14. EA-331 The Royal Bank of Scotland plc | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EA-331 The Royal Bank of Scotland plc Order authorizing The Royal Bank of Scotland plc to export electric energy to Mexico PDF icon EA-331 The Royal Bank of Scotland plc More ...

  15. ALT-GTS-Stem Fabrication

    SciTech Connect (OSTI)

    Thuan Nguyen

    2008-09-25

    In 2007, a study investigated options to manufacture stems utilizing methods that would replace crush form grinding while maintaining or improving quality at a comparative cost. Crush form grinding is a special process used at the Kansas City Plant to finish stem sections of reservoir products. However, crush form grinding is a complex process with many variables affecting the final product. This study identified two potential methods that can be applied to stems. Profile grinding was investigated in 2007. This project continued in 2008 proving that single point turning on a multi-turret is an option with additional benefits. It is an economical way to meet floor space limitations for our KCRIMS mission.

  16. The STEM Path to Antarctica

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM skills Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue:May 2016 all issues All Issues » submit The STEM Path to Antarctica Nina Lanza, a staff scientist at the Laboratory realizes her dream of being a space scientist and hunts for space rocks at the ends of the earth March 1, 2016 Nina Lanza, a staff scientist on the ChemCam instrument team for the Curiosity Mars Rover, spent two month on the frozen glaciers with the Antarctica

  17. OVERVIEW of STEM MENTORING CAFÉ MODEL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    http:energy.govdiversitystem-mentoring-caf OVERVIEW of STEM MENTORING CAF MODEL To help ... quick-show-and-tell chats about their STEM careers and how their work impacts society. ...

  18. Forensic DNA data banking by state crime labortaories

    SciTech Connect (OSTI)

    McEwen, J.E.

    1995-06-01

    This article reports the results of a survey of the responsible crime laboratories in the first 19 states with legislation establishing forensic DNA data banks. The survey inquired into the labs` policies and procedures regarding the collection, storage, and analysis of samples; the retention of samples and data; search protocols; access to samples and data by third parties; and related matters. The research suggests that (1) the number of samples collected from convicted offenders for DNA data banking has far surpassed the number that have been analyzed; (2) data banks have already been used in a small but growing number of cases, to locate suspects and to identify associations between unresolved cases; (3) crime labs currently plan to retain indefinitely the samples collected for their data banks; and (4) the nature and extent of security safeguards that crime labs have implemented for their data banks vary among states. The recently enacted DNA Identification Act (1994) will provide $40 million in federal matching grants to states for DNA analysis activities, so long as states comply with specified quality-assurance standards, submit to external proficiency testing, and limit access to DNA information. Although these additional funds should help to ease some sample backlogs, it remains unclear how labs will allocate the funds, as between analyzing samples for their data banks and testing evidence samples in cases without suspects. The DNA Identification Act provides penalties for the disclosure or obtaining of DNA data held by data banks that participate in CODIS, the FBI`s evolving national network of DNA data banks, but individual crime labs must also develop stringent internal safeguards to prevent breaches of data-bank security. 9 refs., 3 tabs.

  19. American Indian Research and Education Initiative (AIREI) | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy American Indian Research and Education Initiative (AIREI) American Indian Research and Education Initiative (AIREI) American Indian Research and Education Initiative (AIREI) Through a pilot program announced last year, the Energy Department, the American Indian Higher Education Consortium and the American Indian Science and Engineering Society have partnered to bring science, technology, engineering and mathematics (STEM) research and education funding to our nation's Tribal colleges

  20. Data banks for risk assessment at the Savannah River Site

    SciTech Connect (OSTI)

    Durant, W.S.; Lux, C.R.; Baughman, D.F.

    1990-01-01

    The Savannah River Site maintains a compilation of operating problems and equipment failures that have occurred in the fuel reprocessing and other areas in the form of computerized data banks. 14 refs., 25 figs.

  1. Energy Secretary Moniz and Export-Import Bank Chairman Hochberg...

    Energy Savers [EERE]

    (Ex-Im Bank) for a tour of the First Solar manufacturing plant in Perrysburg, ... these investments are making to the nation's goal of a low-carbon energy future. ...

  2. DOE's Disposition of Excess Real Property Status of Banked Square...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    This report details the Department's excess area elimination efforts through FY 2014. ... FY 2014 Net Banked Area (square feet) 24,035,398 1,212,147 25,247,545 8,583,326 422,521 ...

  3. BankInvest Technology AS | Open Energy Information

    Open Energy Info (EERE)

    that manages the BankInvest New Energy Solutions fund as well as funds in IT and biotechnology. Coordinates: 55.67631, 12.569355 Show Map Loading map......

  4. Red Bank, New Jersey: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Hide Map This article is a stub. You can help OpenEI by expanding it. Red Bank is a borough in Monmouth County, New Jersey. It falls under New Jersey's 6th...

  5. Red Bank, Tennessee: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Hide Map This article is a stub. You can help OpenEI by expanding it. Red Bank is a city in Hamilton County, Tennessee. It falls under Tennessee's 3rd...

  6. Energy Department Women Flex STEM Muscle for Nation's Youth

    Broader source: Energy.gov [DOE]

    Eighty 4th through 8th grade students and educators were special guests at the White House to kick off the administration’s “Week at the National Labs” event from Feb. 29-March 5. Among special invitees were three women from the Office of Energy Efficiency and Renewable Energy (EERE), who led hands-on activities and mentored the youth during the “Day at the Lab” event. The EERE team wowed the students with technology displays and showcased the Energy Department’s growing pipeline of women in STEM.

  7. #WomenInSTEM: Advancing Our Energy Future with STEM Mentorships |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Advancing Our Energy Future with STEM Mentorships #WomenInSTEM: Advancing Our Energy Future with STEM Mentorships October 17, 2014 - 1:23pm Addthis Watch the video above to meet Karen Lefkowitz, the the latest profile in Energy.gov's #WomenInSTEM video series. | Video by Matty Greene, Energy Department. Dr. Elizabeth Sherwood-Randall Dr. Elizabeth Sherwood-Randall Deputy Secretary of Energy Matty Greene Matty Greene Former Videographer #WomenInSTEM Our #WomenInSTEM video

  8. Building America Expert Meeting: Energy Savings You Can Bank On |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Energy Savings You Can Bank On Building America Expert Meeting: Energy Savings You Can Bank On On October 12, 2011, Building America team Alliance for Residential Building Innovation conducted an Expert Meeting on the topic of performance guarantees and financing vehicles for Energy Efficiency Upgrades. The meeting brought together technical, policy, and financial experts, including researchers, experienced installation contractors, and innovative energy business

  9. Tube Bank C - metal wastage: status report, August 1983

    SciTech Connect (OSTI)

    Not Available

    1984-01-01

    The Experimental Pressurised Fluidized Bed Combustion Facility at Grimethorpe, South Yorkshire, UK incorporates an in-bed tube bank. During the operation of the facility between June and September 1982, an unexpectedly high degree of metal wastage occurred from the external surfaces of this tube bank. Measures were taken to reduce the rate of metal wastage and extend the life of the tube bank, which was subsequently replaced in July 1983 after a total operating period of 1222 hours of coal burning. Using small-scale fluidized bed cold models, experimental investigations were carried out to determine measures to reduce the metal wastage. The results indicated that metal wastage would be reduced by the following changes: a reduction in the fluidizing velocity; the attachment of studs or axial fins to the tubes; a reduction in the height of the space between the distributor plate and the bottom of the tube bank; and the elimination, where possible of any large gaps within the tube bank. Such changes have been incorporated into the design of the replacement tube bank. This has now been installed and has experienced significantly less metal wastage. 9 references, 6 tables, 34 figures.

  10. Cheyney University Curriculum and Infrastructure Enhamcement in STEM

    SciTech Connect (OSTI)

    Eva, Sakkar Ara

    2014-09-30

    Cheyney University is the oldest historically Black educational institution in America. Initially established as a “normal” school emphasizing the matriculation of educators, Cheyney has become a comprehensive university, one of 14 state universities comprising the Pennsylvania State System of Higher Education (PASSHE). Cheyney University graduates still become teachers, but they also enter such fields as journalism, medicine, science, mathematics, law, communication and government. Cheyney University is a small state owned HBCU with very limited resource. At present the university has about a thousand students with 15% in STEM. The CUCIES II grant made significant contribution in saving the computer science program from being a discontinued program in the university. The grant enabled the university to hire a temporary faculty to teach in and update the computer science program. The program is enhanced with three tracks; cyber security, human computer interaction and general. The updated and enhanced computer science program will prepare professionals in the area of computer science with the knowledge, skills, and professional ethic needed for the current market. The new curriculum was developed for a professional profile that would focus on the technologies and techniques currently used in the industry. With faculty on board, the university worked with the department to bring back the computer science program from moratorium. Once in the path of being discontinued and loosing students, the program is now growing. Currently the student number has increased from 12 to 30. University is currently in the process of hiring a tenure track faculty in the computer science program. Another product of the grant is the proposal for introductory course in nanotechnology. The course is intended to generate interest in the nanotechnology field. The Natural and Applied Science department that houses all of the STEM programs in Cheyney University, is currently working to bring back environmental science program from moratorium. The university has been working to improve minority participation in STEM and made significant stride in terms of progressing students toward graduate programs and into professoriate track. This success is due to faculty mentors who work closely with students to guiding them through the application processes for research internship and graduate programs; it is also due to the university forming collaborative agreements with research intensive institutions, federal and state agencies and industry. The grant assisted in recruiting and retaining students in STEM by offering tuition scholarship, research scholarship and travel awards. Faculty professional development was supported by the grant by funding travel to conferences, meetings and webinar. As many HBCU Cheyney University is also trying to do more with less. As the STEM programs are inherently expensive, these are the ones that suffer more when resources are scarce. One of the goals of Cheyney University strategic plan is to strengthen STEM programs that is coherent with the critical skill need of Department of Energy. All of the Cheyney University STEM programs are now located in the new science building funded by Pennsylvania state.

  11. STEM Internships, Fellowships, and Mentoring | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    engagement, interest in STEM and their perception of its value to their lives, or their ... National Laboratory's Black Leadership Committee for middle and high school students. ...

  12. Women in STEM Panel @Mesa Public Library

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Women in STEM Panel @Mesa Public Library Women in STEM Panel @Mesa Public Library WHEN: Oct 15, 2015 7:00 PM - Feb 12, 2015 8:30 PM WHERE: Mesa Public Library 2400 Central Ave, Los Alamos, NM 87544 SPEAKER: Nicole-Lloyd-Ronning, Teri Roberts and Sandy Frost CATEGORY: Bradbury INTERNAL: Calendar Login Ada Lovelace day image Event Description Join the speakers for a conversation about women in STEM. In association with the Bradbury Science Museum. Women in STEM Panel @Mesa Public Library Join

  13. OVERVIEW of STEM MENTORING CAF MODEL

    Energy Savers [EERE]

    a volunteer contact sheet, using STEM mentor's contact information and profile pictures. DOE and the museum will work collaboratively. Contact sheet will need to be compiled...

  14. STEM: Volunteer Training Engaging Middle School Students

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    in engineering, computer science, and physical sciences. * STEM is an equity issue. ... practices with others, using scientific language and tools. * Strand 6: Think about ...

  15. OVERVIEW of STEM MENTORING CAF MODEL

    Broader source: Energy.gov (indexed) [DOE]

    To help engage middle-school students and science, technology, engineering, and mathematics (STEM) professionals around the country, in 2014 the Departments of Energy and...

  16. STEM

    National Nuclear Security Administration (NNSA)

    has been named a 2013 Black Engineer of the Year Award (BEYA) Minority in Research Science Emerald Honoree in the category of Most Promising Scientist - Government.

    The...

  17. Department of Energy STEM Mentoring Program

    Broader source: Energy.gov [DOE]

    The STEM Mentoring Program matches undergraduate students in the DC area with STEM professionals who work at the Energy Department for in-person mentoring, lectures & events, and training sessions from the Office of the Chief Human Capital Officer at the Energy Department.

  18. First Annual Federal STEM Volunteer Fair | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office of Science eCYBERMISSION FIRST The Fishing School Frederick County Public Schools Future Next Girls and STEM Great Minds in STEM Higher Achievement Howard University Middle ...

  19. Planning and Participation in a STEM Mentoring Cafe | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    what exciting projects they have currently, and why STEM matters to our society. ... Home page: http:www.energy.govdiversitystem-mentoring-caf PDF icon Overview of the STEM ...

  20. The STEM Promise: Opportunities for Economic Empowerment. Join...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The STEM Promise: Opportunities for Economic Empowerment. Join the Conversation on April 8. The STEM Promise: Opportunities for Economic Empowerment. Join the Conversation on April ...

  1. Pantex operator supports women in STEM luncheon | National Nuclear...

    National Nuclear Security Administration (NNSA)

    Related Topics engineering pantex STEM women Related News Who's on FIRST? Inspiring STEM through robotics Wind farm generating more renewable energy than expected for Pantex NNSA ...

  2. Developmental Control of Lignification in Stems of Lowland Switchgrass...

    Office of Scientific and Technical Information (OSTI)

    Developmental Control of Lignification in Stems of Lowland Switchgrass Variety Alamo and ... Citation Details In-Document Search Title: Developmental Control of Lignification in Stems ...

  3. Nonclinical safety strategies for stem cell therapies

    SciTech Connect (OSTI)

    Sharpe, Michaela E.; Morton, Daniel; Rossi, Annamaria

    2012-08-01

    Recent breakthroughs in stem cell biology, especially the development of the induced pluripotent stem cell techniques, have generated tremendous enthusiasm and efforts to explore the therapeutic potential of stem cells in regenerative medicine. Stem cell therapies are being considered for the treatment of degenerative diseases, inflammatory conditions, cancer and repair of damaged tissue. The safety of a stem cell therapy depends on many factors including the type of cell therapy, the differentiation status and proliferation capacity of the cells, the route of administration, the intended clinical location, long term survival of the product and/or engraftment, the need for repeated administration, the disease to be treated and the age of the population. Understanding the product profile of the intended therapy is crucial to the development of the nonclinical safety study design.

  4. Energy Department Dream Team Opens Students' Eyes to Limitless STEM

    Office of Environmental Management (EM)

    Employees give to local food bank Employees give to local food bank September 12, 2014 - 11:00am Addthis This is the fifth year OREM employees have participated in the annual Feds Feed Families summer campaign that helps replenish local food banks and raises awareness about the prevalence of hunger. This is the fifth year OREM employees have participated in the annual Feds Feed Families summer campaign that helps replenish local food banks and raises awareness about the prevalence of hunger. OAK

  5. Development of the Cummins 5.9 L for the Gale Banks Engineering...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Cummins 5.9 L for the Gale Banks Engineering Dodge Dakota Sidewinder Development of the Cummins 5.9 L for the Gale Banks Engineering Dodge Dakota Sidewinder 2003 DEER ...

  6. Environmental effects of SO{sub 2} trading and banking

    SciTech Connect (OSTI)

    Burtraw, D.; Mansur, E.

    1999-10-15

    The widely acknowledged innovation of Title IV of the 1990 Clean Air Act Amendments is sulfur dioxide allowance trading, which is designed to encourage the electricity industry to minimize the cost of reducing emissions. Few studies have examined the environmental effects of trading, and none have explored the effects of banking. The authors used an integrated assessment computer model, the Tracking and Analysis Framework, to evaluate changes in emissions of SO{sub 2}, atmospheric concentrations of sulfates and deposition of sulfur, and public health benefits from reduced exposure to SO{sub 2} and particulate matter. They assessed geographic and temporal changes at the state level that result from trading and banking and compared them with estimated cost savings. The findings are not consistent with the feats of the program's critics. In the East and Northeast including New York State, an area of particular concern, the authors found that health benefits increase and sulfur deposition decrease slightly as a result of trading. Nationally, trading results in health-related benefits in addition to significant cost savings. Banking changes the timing of emissions, but the geographic consequence of banking is varied.

  7. Banking on Solar: New Opportunities for Lending (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2014-08-01

    The U.S. solar industry is a $13.7 billion market with roughly 450,000 systems in place. Bank and credit union lending for solar system deployment represents a valuable new opportunity for lenders to expand their consumer and commercial customer relationships, bring on new relationships and open a new asset class category.

  8. DOE Hosts Festival to Collect Items for Area Food Banks

    Broader source: Energy.gov [DOE]

    WASHINGTON, D.C. – Deputy Secretary of Energy Daniel Poneman and a representative of the Capital Area Food Bank are among the guest speakers at an event this Tuesday, July 31, to collect food items for the DOE Feeds Families drive.

  9. EM Rockets Past Target for Donations to Stock Food Banks

    Broader source: Energy.gov [DOE]

    WASHINGTON, D.C. – EM donated close to 50,000 pounds of non-perishable items to the Fourth Annual Feds Feed Families Campaign, easily surpassing its target of 19,120 pounds. All donations were delivered directly to food banks to provide goods to the needy.

  10. Lab Director focuses on STEM education at TEDxABQ

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Department of Energy ADM Leads to Petroleum-Free Glycol Production Facility Lab Breakthrough: ADM Leads to Petroleum-Free Glycol Production Facility May 22, 2012 - 9:38am Addthis Pacific Northwest National Laboratory discovered a viable way to deliver propylene glycol from feedstock, including glycerin byproducts. ADM licensed that technology and in 2010 completed construction and commissioning of its full-scale production facility for the sole purpose of commercializing the PGRS process.

  11. Fermi National Accelerator Laboratory October 2013 STEM Educational...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to introduce youth to the world of science and trains college and university students in high-tech research and development. K-12 students FY2012 FY2013 K-12 teachers FY2012...

  12. Creating Educational Opportunities for Minorities in STEM | Department of

    Broader source: Energy.gov (indexed) [DOE]

    tip sheet on covering heated, open vessels provides how-to advice for improving industrial steam systems using low-cost, proven practices and technologies. STEAM TIP SHEET #19 PDF icon Cover Heated, Open Vessels (January 2012) More Documents & Publications Improving Steam System Performance: A Sourcebook for Industry, Second Edition Use Steam Jet Ejectors or Thermocompressors to Reduce Venting of Low-Pressure Steam Recover Heat from Boiler Blowdown

    computers, a product category covered by

  13. Educational Opportunities in Bioenergy - NREL | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NREL Educational Opportunities in Bioenergy - NREL NREL presentation about the educational opportunities at the lab. PDF icon nrel_opportunities_bioenergy.pdf More Documents & Publications Powerpoint on STEM Programs EERE Resources for Undergraduate Students Department of Energy Research Opportunities for Historically Black Colleges and Universities

  14. Employees Inspire Others as STEM Role Models

    Broader source: Energy.gov [DOE]

    CARLSBAD, N.M. – Four employees at the Waste Isolation Pilot Plant (WIPP) participated in a conference created to inspire girls to pursue opportunities in science, technology, engineering and math (STEM).

  15. 2013 Women of Color STEM Conference

    Broader source: Energy.gov [DOE]

    For Students looking to meet top employers, to take advantage of onsite resources designed to enhance job search, to enhance their academic career, as well as to get tools for a successful STEM...

  16. Equal Opportunity Publications’ STEM Diversity Career Expo

    Broader source: Energy.gov [DOE]

    Meet qualified job candidates face-to-face at EOP’s STEM Diversity Career Expo hosted by Equal Opportunity Publications (EOP). EOP publishes of seven nationally recognized career guidance and...

  17. Find Your STEM Role Model: Google+ Hangout

    Broader source: Energy.gov [DOE]

    NASA and the Energy Department are teaming up on Wednesday, March 5, 2014 at 1pm EST to host a Google+ Hangout, showcasing women in STEM at NASA and Energy

  18. Analysis of crystallization data in the Protein Data Bank

    SciTech Connect (OSTI)

    Kirkwood, Jobie; Hargreaves, David; O’Keefe, Simon; Wilson, Julie

    2015-09-23

    In a large-scale study using data from the Protein Data Bank, some of the many reported findings regarding the crystallization of proteins were investigated. The Protein Data Bank (PDB) is the largest available repository of solved protein structures and contains a wealth of information on successful crystallization. Many centres have used their own experimental data to draw conclusions about proteins and the conditions in which they crystallize. Here, data from the PDB were used to reanalyse some of these results. The most successful crystallization reagents were identified, the link between solution pH and the isoelectric point of the protein was investigated and the possibility of predicting whether a protein will crystallize was explored.

  19. Higher Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Higher Education Higher Education Explore the multiple dimensions of a career at LANL: work with brilliant minds in an inclusive environment rich in intellectual...

  20. Education Buildings

    U.S. Energy Information Administration (EIA) Indexed Site

    Education Characteristics by Activity... Education Education buildings are buildings used for academic or technical classroom instruction, such as elementary, middle, or high...

  1. Expert Meeting Report: Energy Savings You Can Bank On

    Energy Savers [EERE]

    Energy Savings You Can Bank On Mark Berman, Jeremy Springer, Pepper Smith, and Erik Porse Alliance for Residential Building Innovation )HEUXDU\ 2013 NOTICE This report was prepared as an account of work sponsored by an agency of the United States government. Neither the United States government nor any agency thereof, nor any of their employees, subcontractors, or affiliated partners makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy,

  2. Diversity & Inclusion: Outreach & Education Diversity | Argonne National

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory In the News Argonne hosts Cyber Defense Competition Homeland Security News Wire Three tips to land first job after college The Charlotte Post IC Catholic Prep Students Explore Science and Engineering at Argonne National Lab Chicago Tribune Outreach & Education Argonne engages students in science, technology, engineering and mathematics (STEM) education through energy, environment, science and engineering programs. The lab develops educational and outreach programs based on the

  3. Albert Einstein Distinguished Educator Fellowship (AEF) Program Homepage |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    U.S. DOE Office of Science (SC) Einstein Fellowship Home Albert Einstein Distinguished Educator Fellowship (AEF) Program Einstein Fellowship Home Eligibility Benefits Obligations How to Apply Key Dates Frequently Asked Questions Fellows Central Contact WDTS Home The Albert Einstein Distinguished Educator Program The Albert Einstein Distinguished Educator (AEF) Program provides opportunities for accomplished K-12 STEM teachers to spend 11 months working in a Federal agency or U.S.

  4. Wetland mitigation banking for the oil and gas industry: Assessment, conclusions, and recommendations

    SciTech Connect (OSTI)

    Wilkey, P.L.; Sundell, R.C.; Bailey, K.A.; Hayes, D.C.

    1994-01-01

    Wetland mitigation banks are already in existence in the United States, and the number is increasing. To date, most of these banks have been created and operated for mitigation of impacts arising from highway or commercial development and have not been associated with the oil and gas industry. Argonne National Laboratory evaluated the positive and negative aspects of wetland mitigation banking for the oil and gas industry by examining banks already created for other uses by federal, state, and private entities. Specific issues addressed in this study include (1) the economic, ecological, and technical effectiveness of existing banks; (2) the changing nature of local, state, and federal jurisdiction; and (3) the unique regulatory and jurisdictional problems affecting bank developments associated with the oil and gas industry.

  5. STEM summit challenges employers (Inside Business) | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STEM summit challenges employers (Inside Business) External Link: http://insidebiz.com/news/jeff-labs-stem-summit-challenges-employers By jlab_admin on Fri, 2012-04-06

  6. Planning and Participation in a STEM Mentoring Cafe | Department...

    Broader source: Energy.gov (indexed) [DOE]

    in a STEM Mentoring Cafe At a STEM Mentoring Caf, we recruit 5th through 8th grade students and their teachers to spend a few hours engaged in quick show-and-tell chats with...

  7. STEM Volunteer Training: Engaging Middle School Students | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Volunteer Training: Engaging Middle School Students STEM Volunteer Training: Engaging Middle School Students August 13, 2015 3:00PM to 4:00PM EDT Register: https:...

  8. STEM Mentoring Caf- Engaging Young Women in an Authentic Mentoring...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    role in choosing a career path. In addition, the more students identify with same-sex experts the more likely they will be to pursue a STEM career. So not only did the STEM...

  9. Registration for the 2015 Conference for Young Women in STEM...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Registration for the 2015 Conference for Young Women in STEM is OPEN October 15, 2014 The 2015 Young Women's Conference in STEM will be held on Thursday, March 19, 2015 at...

  10. Wrapping Up: Our Conversation on Increasing Diversity in STEM...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    While industry demand for science, technology, engineering and math (STEM) professionals ... in science, technology, engineering & math disciplines. | Infographic by Sarah ...

  11. Banks Lake Fishery Evaluation Annual Report 2002-2003.

    SciTech Connect (OSTI)

    Polacek, Matt; Knuttgen, Kamia; Shipley, Rochelle

    2003-11-01

    The Washington Department of Fish and Wildlife implemented the Banks Lake Fishery Evaluation Project (BLFEP) in September 2001 with funds from the Bonneville Power Administration. Fiscal Year (FY) 2001 of the BLFEP was used to gather historic information, establish methods and protocols, collect limnology data, and conduct the first seasonal fish surveys. FY 2002 was used to continue seasonal fish and lakewide creel surveys and adjust methods and protocols as needed. Water quality parameters were collected monthly from February to May and bi-monthly from June to August. Banks Lake water temperatures began to increase in April and stratification was apparent by June at all 3 limnology collection sites. By late August, the thermocline had dropped to nearly 20 meters deep, with 16-17 C temperatures throughout the epilimnion. Dissolved oxygen levels were generally above 10 mg/L until August when dissolved oxygen dropped near or below 5 mg/L below 20-meters deep. Secchi depths ranged from 2.5-8 meters and varied by location and date. Nearshore and offshore fish surveys were conducted in October 2002 and May and July 2003 using boat electrofishing, fyke net, gill net, and hydroacoustic surveys. Yellow Perch Perca flavescens (32 %) and cottid spp. (22 %) dominated the nearshore species composition in October; however, by May yellow perch (12 %) were the third most common species followed by smallmouth bass Micropterous dolomieui (34 %) and lake whitefish Coregonus clupeaformis (14 %). Lake whitefish dominated the offshore catch during October (78 %) and May (81 %). Fish diet analysis indicated that juvenile fishes consumed primarily insects and zooplankton, while adult piscivores consumed cottids spp. and yellow perch most frequently. For FY 2002, the following creel statistics are comprehensive through August 31, 2003. The highest angling pressure occurred in June 2003, when anglers were primarily targeting walleye and smallmouth bass. Boat anglers utilized Steamboat State Park more frequently than any other boat ramp on Banks Lake. Shore anglers used the rock jetty at Coulee City Park 76 % of the time, with highest use occurring from November through April. An estimated total of 11,915 ({+-}140 SD) smallmouth bass, 6,412 ({+-}59 SD) walleye, 5,470 ({+-}260 SD) rainbow trout, and 1,949 ({+-}118 SD) yellow perch were harvested from Banks Lake in FY 2002. Only 3 kokanee were reported in the catch during the FY 2002 creel survey. In the future, data from the seasonal surveys and creel will be used to identify potential factors that may limit the production and harvest of kokanee, rainbow trout, and various spiny-rayed fishes in Banks Lake. The limiting factors that will be examined consist of: abiotic factors including water temperature, dissolved oxygen levels, habitat, exploitation and entrainment; and biotic factors including food limitation and predation. The BLFEP will also evaluate the success of several rearing and stocking strategies for hatchery kokanee in Banks Lake.

  12. Case Study: Fuel Cells Increase Reliability at First National Bank of Omaha

    SciTech Connect (OSTI)

    2010-12-31

    A case study of the First National Bank of Omaha fuel cell system, covering 1999 through October 2009. The system reduced heating bills by more than $1 million.

  13. Tips for Running an Air Conditioner Without Breaking the Bank | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Tips for Running an Air Conditioner Without Breaking the Bank Tips for Running an Air Conditioner Without Breaking the Bank July 22, 2014 - 3:15pm Addthis Cooling your home doesn't have to break the bank, with these tips you can save money and stay comfortable.| Photo courtesy of ©iStockphoto.com/galinast Cooling your home doesn't have to break the bank, with these tips you can save money and stay comfortable.| Photo courtesy of ©iStockphoto.com/galinast Elizabeth Spencer

  14. World Bank-The Role of Nonmotorized Transport | Open Energy Informatio...

    Open Energy Info (EERE)

    Website: siteresources.worldbank.orgINTURBANTRANSPORTResourceschapter9.pdf Cost: Free World Bank-Role of Nonmotorized Transport Screenshot References: The Role of...

  15. Radiological Worker (RW) and Radiological Control Technician (RCT) Training Exam Banks

    Broader source: Energy.gov [DOE]

    Examination banks are available to DOE Contractors for use with the radiation safety training Handbooks. Questions and answers for these courses have also been prepared by DOE.

  16. Case Study: Fuel Cells Increase Reliability at First National Bank of Omaha

    Fuel Cell Technologies Publication and Product Library (EERE)

    A case study of the First National Bank of Omaha fuel cell system, covering 1999 through October 2009. The system reduced heating bills by more than $1 million.

  17. Data banks for risk assessment at the Savannah River Site

    SciTech Connect (OSTI)

    Durant, W.S.; Townsend, C.S.; Baughman, D.F.; Hang, P.

    1992-01-01

    One of the lessons learned from many years of risk assessment experience is that mistakes of the past are soon forgotten if no method is available to retrieve and review these events. Savannah River Site has maintained a computerized data bank system for recording, retrieving and reviewing its incident history. The system is based on a series of compilations developed primarily for risk assessment but has been found to be invaluable for many other uses such as equipment reliability, project justification, and incident investigations.

  18. Data banks for risk assessment at the Savannah River Site

    SciTech Connect (OSTI)

    Durant, W.S.; Townsend, C.S.; Baughman, D.F.; Hang, P.

    1992-11-01

    One of the lessons learned from many years of risk assessment experience is that mistakes of the past are soon forgotten if no method is available to retrieve and review these events. Savannah River Site has maintained a computerized data bank system for recording, retrieving and reviewing its incident history. The system is based on a series of compilations developed primarily for risk assessment but has been found to be invaluable for many other uses such as equipment reliability, project justification, and incident investigations.

  19. Materials experience of the public domain portions of Tube Bank E' during Test Series A2

    SciTech Connect (OSTI)

    Not Available

    1990-06-01

    The tube banks at the Grimethorpe pressurized fluidized bed combustion facility are discussed. Tube Bank E'' was designed for operation as the in bed heat exchanger during Test Series A2 at the Grimethorpe PFBC Establishment between March and November 1987. The supply of the tube bank resulted from an agreement between Foster Wheeler Development Corporation (FWDC), the US Department of Energy, and the Operating Agent for the British Coal/CEGB Joint Programme on PFBC. The tube bank incorporated features, designed to produce acceptable and predictable wastage characteristics, suggested by both FWDC and BCC/CEGB interests. As part of the agreement between the various parties, it was agreed only data from 55% of the tube bank would enter the public domain. This report describes the tube bank, and describes and discusses the public domain wastage results following a total operating period approaching 1450 hours. It is concluded that although conditions varied throughout Test Series A2, there were no major differences in the aggressiveness of the bed. Armouring devices suggested by FWDC were not successful, but their chromised coatings offered promise. The results from UK proprietary parts of the tube bank indicated that the tube bank metal wastage need not be a life limiting problem for PFBC in-bed heat exchangers. 5 refs., 48 figs., 6 tabs.

  20. Mesenchymal Stem Cells Retain Their Defining Stem Cell Characteristics After Exposure to Ionizing Radiation

    SciTech Connect (OSTI)

    Nicolay, Nils H.; Sommer, Eva; Lopez, Ramon; Wirkner, Ute; Trinh, Thuy; Sisombath, Sonevisay; Debus, Jrgen; Ho, Anthony D.; Saffrich, Rainer; Huber, Peter E.

    2013-12-01

    Purpose: Mesenchymal stem cells (MSCs) have the ability to migrate to lesion sites and undergo differentiation into functional tissues. Although this function may be important for tissue regeneration after radiation therapy, the influence of ionizing radiation (IR) on cellular survival and the functional aspects of differentiation and stem cell characteristics of MSCs have remained largely unknown. Methods and Materials: Radiation sensitivity of human primary MSCs from healthy volunteers and primary human fibroblast cells was examined, and cellular morphology, cell cycle effects, apoptosis, and differentiation potential after exposure to IR were assessed. Stem cell gene expression patterns after exposure to IR were studied using gene arrays. Results: MSCs were not more radiosensitive than human primary fibroblasts, whereas there were considerable differences regarding radiation sensitivity within individual MSCs. Cellular morphology, cytoskeletal architecture, and cell motility were not markedly altered by IR. Even after high radiation doses up to 10 Gy, MSCs maintained their differentiation potential. Compared to primary fibroblast cells, MSCs did not show an increase in irradiation-induced apoptosis. Gene expression analyses revealed an upregulation of various genes involved in DNA damage response and DNA repair, but expression of established MSC surface markers appeared only marginally influenced by IR. Conclusions: These data suggest that human MSCs are not more radiosensitive than differentiated primary fibroblasts. In addition, upon photon irradiation, MSCs were able to retain their defining stem cell characteristics both on a functional level and regarding stem cell marker expression.

  1. Banking on Solar: Debt Finance in Today's Distributed Market (Poster)

    SciTech Connect (OSTI)

    Louder, T.

    2014-10-01

    Over the last two years, several entities - from banks to credit unions to solar finance companies -have rolled out distributed solar-specific loan programs in the United States. These solar-specific loans are a distinct loan in that the underwriting, loan terms, lender security interest, and other programmatic aspects are designed exclusively for the financing of solar installations. Until recently, loan financing for distributed solar installations was largely through home equity loans, commercial loans, and other standardized loan products available to homeowners and businesses for general expenditures. However, as the U.S. solar market matures, so too are its financing options, and solar-specific loans stand to gain market share. This poster was presented at the Solar Power International conference in Las Vegas, NV in October 2014.

  2. Educational Programs | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Calling all Teachers Do you know how to design a fuel-efficient, affordable car for the future? Learn how by joining us June 21-23 for an energy-filled NGSS workshop on the engineering design process. More Register for the 7th Annual STEM Summit Join education and business leaders from across the state in exploring opportunities to advance student learning in STEAM. More Can Biofuels Green Aviation? Teachers can explore answers to this question by signing up for the iBIO Institute's Farm to

  3. Educational Programs | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Calling all Teachers Do you know how to design a fuel-efficient, affordable car for the future? Learn how by joining us June 21-23 for an energy-filled NGSS workshop on the engineering design process. More Register for the 7th Annual STEM Summit Join education and business leaders from across the state in exploring opportunities to advance student learning in STEAM. More Can Biofuels Green Aviation? Teachers can explore answers to this question by signing up for the iBIO Institute's Farm to

  4. Joining mechanism with stem tension and interlocked compression ring

    DOE Patents [OSTI]

    James, Allister W.; Morrison, Jay A.

    2012-09-04

    A stem (34) extends from a second part (30) through a hole (28) in a first part (22). A groove (38) around the stem provides a non-threaded contact surface (42) for a ring element (44) around the stem. The ring element exerts an inward force against the non-threaded contact surface at an angle that creates axial tension (T) in the stem, pulling the second part against the first part. The ring element is formed of a material that shrinks relative to the stem by sintering. The ring element may include a split collet (44C) that fits partly into the groove, and a compression ring (44E) around the collet. The non-threaded contact surface and a mating distal surface (48) of the ring element may have conic geometries (64). After shrinkage, the ring element is locked onto the stem.

  5. Giving Back Through Our Talented STEM Professionals | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Giving Back Through Our Talented STEM Professionals Giving Back Through Our Talented STEM Professionals January 17, 2014 - 4:51pm Addthis Events like Argonne National Laboratory's annual Introduce a Girl to Engineering Day are produced with the volunteer support of the Department of Energy's STEM professionals. Above, Director Dot Harris visits the event in 2013. Events like Argonne National Laboratory's annual Introduce a Girl to Engineering Day are produced with the volunteer support of the

  6. Mentoring Our Future Generation of STEM Professionals | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Mentoring Our Future Generation of STEM Professionals Mentoring Our Future Generation of STEM Professionals March 30, 2011 - 4:50pm Addthis Bill Valdez Bill Valdez Director of Workforce Management How can I participate? Female STEM students in the Washington, D.C. metropolitan area are encouraged to apply and female employees at the Department's headquarters are encouraged to sign up as mentors. Visit http://diversity.energy.gov for more information. Yesterday, the Department of

  7. Women in STEM careers: Breaking down barriers | Argonne National...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the number of women in Science, Technology, Engineering, and Mathematics (STEM) careers. ... Scientist I was interested in mathematics and problem solving from a very early ...

  8. Celebrating our work with Native American Students in STEM During...

    Broader source: Energy.gov (indexed) [DOE]

    This partnership focuses on career opportunities for American Indians. We especially want to increase access to science, technology, engineering, and mathematics (STEM) programs ...

  9. LAYC Career Academy STEM Fair | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    LAYC Career Academy STEM Fair LAYC Career Academy STEM Fair May 30, 2014 2:30PM to 4:00PM EDT Join us on May 30th for the Latin American Youth Center (LAYC) Career Academy's Science, Technology, Engineering, and Mathematics (STEM) Fair, which will be held at the following location: LAYC Career Academy 3047 15th St. NW Washington, DC 20009 The event will start with a roundtable discussion of Latinos in STEM, with a first look at the new Spanish translation of the Energy Literacy Framework.

  10. Celebrating the History of Women in STEM | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the History of Women in STEM Celebrating the History of Women in STEM March 1, 2016 - 11:30am Addthis Celebrating the History of Women in STEM Allison Lantero Allison Lantero Digital Content Specialist, Office of Public Affairs Carly Wilkins Carly Wilkins Multimedia Designer How can I participate? Follow the Energy Department on Instagram. On Thursday mornings in March, we'll post a new illustrated portrait of an important woman in a STEM field. Guess who she is, then look for the answer at 3

  11. National Geographic Hosts the Energy Department's STEM Mentoring...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    By sharing the excitement of cutting-edge careers in science, technology, engineering, and math (STEM), professionals are helping dreams take shape for these young people. The ...

  12. President Obama Announces New Plan to Create STEM Master Teaching...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    create a national Science, Math, Technology, and Engineering (STEM) Master Teacher Corps. ... receive additional resources to mentor math and science teachers, inspire students, ...

  13. Case Study: Fuel Cells Increase Reliability at First National Bank of Omaha

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    | Department of Energy Increase Reliability at First National Bank of Omaha Case Study: Fuel Cells Increase Reliability at First National Bank of Omaha First National Bank of Omaha installed a fuel cell system in 1999 to provide primary power to its data center in Omaha, Nebraska. In more than 89,000 hours of operation through October 2009, the system is estimated to have reduced heating bills by more than $1 million. An independent third party verified that the designed total power system

  14. Energy Secretary Moniz and Export-Import Bank Chairman Hochberg to Visit

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    First Solar Facility in Perrysburg, Ohio | Department of Energy Secretary Moniz and Export-Import Bank Chairman Hochberg to Visit First Solar Facility in Perrysburg, Ohio Energy Secretary Moniz and Export-Import Bank Chairman Hochberg to Visit First Solar Facility in Perrysburg, Ohio February 14, 2015 - 6:35pm Addthis News Media Contact 202 586 4940 RSVP@hq.doe.gov Energy Secretary Moniz and Export-Import Bank Chairman Hochberg to Visit First Solar Facility in Perrysburg, Ohio WASHINGTON- On

  15. In-bed tube bank for a fluidized-bed combustor

    DOE Patents [OSTI]

    Hemenway, Jr., Lloyd F.

    1990-01-01

    An in-bed tube bank (10) for a fluidized bed combustor. The tube bank (10) of the present invention comprises one or more fluid communicating boiler tubes (30) which define a plurality of selectively spaced boiler tube sections (32). The tube sections (32) are substantially parallel to one another and aligned in a common plane. The tube bank (10) further comprises support members (34) for joining adjacent tube sections (32), the support members (34) engaging and extending along a selected length of the tube sections (32) and spanning the preselected space therebetween.

  16. #STEM: Join Assistant Secretary Hoffman for a Women in STEM Tweetup March 22

    Broader source: Energy.gov [DOE]

    Leaders from the Department of Energy, joined by representatives from across the Federal Government, will host a conversation about women in science, technology, engineering, and math (STEM) on Twitter on Thursday, March 22, 2012 at 2:30 pm EDT. DOE's Assistant Secretary for Electricity Delivery and Energy Reliability Patricia Hoffman and Technology Transfer Coordinator Dr. Karina Edmonds will host the Tweetup.

  17. STEM Mentoring Café and Day at the Lab | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM Mentoring Café and Day at the Lab STEM Mentoring Café and Day at the Lab STEM Mentoring Café and Day at the Lab View All Maps Addthis

  18. K-12 Educators | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    K-12 Educators Workforce Development for Teachers and Scientists (WDTS) WDTS Home About Science Undergraduate Laboratory Internships (SULI) Community College Internships (CCI) Visiting Faculty Program (VFP) at DOE Laboratories DOE Office of Science Graduate Student Research (SCGSR) Program Albert Einstein Distinguished Educator Fellowship (AEF) Program DOE National Science Bowl® (NSB) STEM Resources Undergraduate and Graduate Students K-12 Educators Outreach Contact Information Workforce

  19. Feds Feed Families Wraps Up Successful Campaign to Stock Area Food Banks

    Broader source: Energy.gov [DOE]

    WASHINGTON, D.C. – The fourth annual Feds Feed Families, an effort by DOE and other federal agencies to stock area food banks, has entered the homestretch of its campaign that ends this month.

  20. World Bank eAtlas of Global Development | Open Energy Information

    Open Energy Info (EERE)

    World Bank eAtlas of Global Development1 "This eAtlas, a new online companion to Atlas of Global Development, third edition, builds on the Atlas topics, allowing you to...

  1. World Bank-MENA Regional-NAMAs and Corresponding Climate Finance...

    Open Energy Info (EERE)

    analysis, Background analysis Website http:www.worldbank.org UN Region Northern Africa, Western Asia References World Bank1 This article is a stub. You can help OpenEI...

  2. World Bank-Morocco Study on the Impact of Climate Change on the...

    Open Energy Info (EERE)

    Morocco Study on the Impact of Climate Change on the Agricultural Sector Jump to: navigation, search Name World Bank-Morocco Study on the Impact of Climate Change on the...

  3. EM Employees at West Valley Help Beat Goal for Food Banks

    Broader source: Energy.gov [DOE]

    WEST VALLEY, N.Y. – EM employees and their contractor counterparts at the West Valley Demonstration Project (WVDP) have supported their local food banks for several years, and this year was no exception.

  4. Tube bank metal wastage in the Grimethorpe PFBC. [Pressurized fluidized bed combustor

    SciTech Connect (OSTI)

    Not Available

    1984-02-01

    During hot commissioning tests of the Grimethorpe PFBC plant, a significant degree of metal wastage was observed on the fireside surfaces of the tube bank. The investigation of this wastage is described and the remedial measures taken are discussed.

  5. SIMULATIONS OF THE AGS MMPS STORING ENERGY IN CAPACITOR BANKS

    SciTech Connect (OSTI)

    MARNERIS,I.; BADEA, V.S.; BONATI, R.; ROSER, T.; SANDBERG, J.

    2007-06-25

    The Brookhaven AGS Main Magnet Power Supply (MMPS) is a thyristor control supply rated at 5500 Amps, +/-9000 Volts. The peak magnet power is 50 MWatts. The power supply is fed from a motor/generator manufactured by Siemens. The generator is 3 phase 7500 Volts rated at 50 MVA. The peak power requirements come from the stored energy in the rotor of the motor/generator. The motor generator is about 45 years old, made by Siemens and it is not clear if companies will be manufacturing similar machines in the future. We are therefore investigating different ways of storing energy for future AGS MMPS operations. This paper will present simulations of a power supply where energy is stored in capacitor banks. Two dc to dc converters will be presented along with the control system of the power section. The switching elements will be IGCT's made by ABB. The simulation program used is called PSIM version 6.1. The average power from the local power authority into the power supply will be kept constant during the pulsing of the magnets at +/-50 MW. The reactive power will also be kept constant below 1.5 MVAR. Waveforms will be presented.

  6. Education Opportunities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Opportunities /collaboration/_assets/images/icon-collaboration.jpg Education Opportunities Partnering with higher education for the future of LANL, fostering relationships that attract students, educators, and potential research and commercial partners. Engineering Institute» Information Science & Technology Institute» Extensive, beneficial collaborations support educational experiences As of 2011, LANL had 375 subcontracts that totaled $80.9 million in universities across 41 states. Our

  7. Higher Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education » Higher Education Higher Education Explore the multiple dimensions of a career at LANL: work with brilliant minds in an inclusive environment rich in intellectual vitality and opportunities for growth. Contact Education Janelle Vigil-Maestas Community Relations & Partnerships (505) 665-4329 Email "The partnership between LANL and regional colleges creates opportunities for students like me to attain challenging and rewarding careers." - Sherry Salas Bachicha Higher

  8. STEM Mentoring Café at the Smithsonian National Museum of Natural...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Allison Lantero Allison Lantero Digital Content Specialist, Office of Public Affairs Matty ... For more information, visit our STEM Mentoring Caf page and our WomenInSTEM video ...

  9. WE-E-BRE-10: Level of Breast Cancer Stem Cell Correlated with...

    Office of Scientific and Technical Information (OSTI)

    WE-E-BRE-10: Level of Breast Cancer Stem Cell Correlated with Tumor Radioresistence: An Indication for Individualized Breast Cancer Therapy Adapted to Cancer Stem Cell Fractions ...

  10. Macrophage characteristics of stem cells revealed by transcriptome profiling

    SciTech Connect (OSTI)

    Charriere, Guillaume M.; Cousin, Beatrice; Arnaud, Emmanuelle; Saillan-Barreau, Corinne; Andre, Mireille; Massoudi, Ali; Dani, Christian; Penicaud, Luc; Casteilla, Louis . E-mail: casteil@toulouse.inserm.fr

    2006-10-15

    We previously showed that the phenotypes of adipocyte progenitors and macrophages were close. Using functional analyses and microarray technology, we first tested whether this intriguing relationship was specific to adipocyte progenitors or could be shared with other progenitors. Measurements of phagocytic activity and gene profiling analysis of different progenitor cells revealed that the latter hypothesis should be retained. These results encouraged us to pursue and to confirm our analysis with a gold-standard stem cell population, embryonic stem cells or ESC. The transcriptomic profiles of ESC and macrophages were clustered together, unlike differentiated ESC. In addition, undifferentiated ESC displayed higher phagocytic activity than other progenitors, and they could phagocytoze apoptotic bodies. These data suggest that progenitors and stem cells share some characteristics of macrophages. This opens new perspectives on understanding stem cell phenotype and functionalities such as a putative role of stem cells in tissue remodeling by discarding dead cells but also their immunomodulation or fusion properties.

  11. The Asian Development Bank`s role in promoting cleaner production in the People`s Republic of China

    SciTech Connect (OSTI)

    Huq, A.; Lohani, B.N.; Jalal, K.F.; Ouano, E.A.R.

    1999-09-01

    The People`s Republic of China (PRC) has the fastest growing economy in the world and is the third largest producer and consumer of energy. At the same time, the PRC`s industrial sector contributes heavily to air and water pollution. Because of the linkages between the production and use of energy and environmental degradation, the PRC, with the active support of bilateral and multilateral aid agencies, including the Asian Development Bank (ADB), is adopting measures that link economic growth to improvements in the environment. The PRC is pursuing a two-pronged strategy that involves implementing priority investment programs and promoting economic reforms. The ADB`s experience shows that the concept of cleaner production (CP) has been widely accepted, but the widespread adoption of CP requires a new way of thinking and new management capacities. In this regard, the PRC is at an early stage of promoting CP, and inadequacies in coordination among relevant agencies remain a key obstacle. To support CP activities, the ADB is participating in a cluster of activities within China that include policy development, capacity building, and financing environmental investments. This article describes the ADB`s current efforts to promote CP in PRC and analyzes the effectiveness of those efforts.

  12. Performance of MOV Stem Lubricants at Elevated Temperatures

    SciTech Connect (OSTI)

    DeWall, Kevin George; Nitzel, Michael Everett; Watkins, John Clifford

    2001-07-01

    This paper documents the results of recent tests sponsored by the U. S. Nuclear Regulatory Commission (NRC) and performed by the Idaho National Engineering and Environmental Laboratory (INEEL). These tests address the effectiveness of the lubricant used on the threaded portion of the valve stem, where the stem nut turns on the stem. Recent testing indicates that an elevated temperature environment can lead to significant increases in the friction coefficient at the stem/stem-nut interface. Most valve actuator qualification tests are performed at room temperature. Similarly, in-service tests are run at ambient plant temperatures, usually 70 to 100F. Since design conditions can lead to valve operating temperatures in the 200 to 300F range, it is important to know whether a temperature-induced increase in friction at the stem/stem-nut interface will prevent the required operation of critical valves. Lubricant aging is another phenomenon that might have deleterious effects on the thrust output of a valve actuator. Laboratory experience and field experience both indicate that after long periods in elevated temperature environments, the lubricants may lose their lubrication qualities. The scope of the current test program includes testing of five different lubricants on four different valve stems. Pending completion of the testing, results of the tests conducted using two of the four stems are discussed. The test series included collection of baseline data at room temperature, single step temperature tests where the temperature of the test setup was elevated directly to 250F, and step testing where the temperature was elevated in steps to 130, 190, and 250F, then returned to 70F. All greases tested showed evidence of physical change after elevated temperature tests. Except for one particular lubricant, all of the greases tested showed increased coefficients of friction at elevated temperatures. Numerous other preliminary conclusions are presented. Recommendations for future research in the area of aged valve stem lubricant performance at elevated temperatures are also presented.

  13. Success at Sandia - Attracting Top Native American STEM Professionals to

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the Department of Energy | Department of Energy Success at Sandia - Attracting Top Native American STEM Professionals to the Department of Energy Success at Sandia - Attracting Top Native American STEM Professionals to the Department of Energy December 7, 2011 - 12:35pm Addthis Dr. Stan Atcitty, a Sandia engineer, works on power electronics and energy storage integration to the grid. A program run by Sandia Labs for Native Americans in STEM paid for his Master's and Ph.D. degrees while he

  14. #WomenInSTEM: A Physicist Focuses on Scientific Advancement

    ScienceCinema (OSTI)

    Capece, Angela

    2014-07-21

    Dr. Capece first became interested in science after learning about NASA's Voyager missions at an early age. In this video, Dr. Capece provides advice for women and girls interested in pursuing careers in STEM fields, like focusing on physics, biology and chemistry at the high school level. This video is part of the Energy Department's #WomenInSTEM video series. At the Energy Department, we're committed to supporting a diverse talent pool of STEM innovators ready to address the challenges and opportunities of our growing clean energy economy.

  15. Educational Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Educational Programs Educational Programs A collaboration between Los Alamos National Laboratory and the University of California at San Diego (UCSD) Jacobs School of Engineering Contact Institute Director Charles Farrar (505) 663-5330 Email UCSD EI Director Michael Todd (858) 534-5951 Professional Staff Assistant Ellie Vigil (505) 667-2818 Email Administrative Assistant Rebecca Duran (505) 665-8899 Email There are two educational components to the Engineering Institute. The Los Alamos Dynamic

  16. Education Grants

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in fourth and seventh grade. The curriculum will also include elements for second language learners and those with special education needs, and is expected to be in place...

  17. Education & Training

    Broader source: Energy.gov [DOE]

    Science and technology a critical sector of the U.S. economy. Learn about opportunities for education and training supported by the Energy Department.

  18. STEM Volunteer Training: Types of Volunteering and Where to Find...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Types of Volunteering and Where to Find Opportunities STEM Volunteer Training: Types of Volunteering and Where to Find Opportunities April 14, 2016 3:00PM to 4:00PM EDT

  19. Mickey Leland Energy Fellowship Seeking Underrepresented Students in STEM

    Broader source: Energy.gov [DOE]

    Are you a student in a science, technology, engineering, or mathematics (STEM) degree looking for a worthwhile summer internship?  Do you currently have a child pursuing these types of degrees?  If...

  20. Women in STEM: Deputy Secretary Liz Sherwood-Randall | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Women in STEM: Deputy Secretary Liz Sherwood-Randall Women in STEM: Deputy Secretary Liz Sherwood-Randall March 22, 2016 - 10:32am Addthis The latest addition to our #WomeninSTEM series is a familiar face, Deputy Secretary Liz Sherwood-Randall. | Video by Simon Edelman, Energy Department. Allison Lantero Allison Lantero Digital Content Specialist, Office of Public Affairs Simon Edelman Simon Edelman Chief Creative Officer #WomeninSTEM Watch the other videos in our #WomeninSTEM video series.

  1. Implementing an X-ray validation pipeline for the Protein Data Bank

    SciTech Connect (OSTI)

    Gore, Swanand; Velankar, Sameer; Kleywegt, Gerard J.

    2012-04-01

    The implementation of a validation pipeline, based on community recommendations, for future depositions of X-ray crystal structures in the Protein Data Bank is described. There is an increasing realisation that the quality of the biomacromolecular structures deposited in the Protein Data Bank (PDB) archive needs to be assessed critically using established and powerful validation methods. The Worldwide Protein Data Bank (wwPDB) organization has convened several Validation Task Forces (VTFs) to advise on the methods and standards that should be used to validate all of the entries already in the PDB as well as all structures that will be deposited in the future. The recommendations of the X-ray VTF are currently being implemented in a software pipeline. Here, ongoing work on this pipeline is briefly described as well as ways in which validation-related information could be presented to users of structural data.

  2. A cost effective battery bank for I sup 2 t testing and evaluation of electrical switchgear

    SciTech Connect (OSTI)

    Reass, W.A.

    1989-01-01

    This paper describes the electrical design and mechanical construction of a 50 kA step switched'' battery bank. Individual fuses protect each of the forty parallel isolated strings of three series (12 V) batteries. Step current waveforms of 12.5 kA, 25 kA, 37.5 kA, and 50 kA are produced by 8 sets of pneumatically driven 20 pole step switches and current limiting stainless steel trombone'' resistors. Inexpensive, yet conservatively designed, Group 65 Motorcraft car batteries are used to give an I{sup 2}t capability of better than 5 {times} 10{sup 9}. The battery bank has well over 1500 shots, with testing of commercial switchgear continuing. In addition to the battery bank engineering data, results of repetitive testing of vacuum interrupters at their I{sup 2}t limit will be provided. 8 figs.

  3. DOE Idaho Operations Office's STEM Partnership with Elementary School

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Grows | Department of Energy Idaho Operations Office's STEM Partnership with Elementary School Grows DOE Idaho Operations Office's STEM Partnership with Elementary School Grows August 31, 2015 - 12:15pm Addthis Students explore the inside of Idaho National Laboratory’s Computer Assisted Virtual Environment. Students explore the inside of Idaho National Laboratory's Computer Assisted Virtual Environment. Students learn about the Idaho National Laboratory’s bus simulator. The INL bus

  4. NREL Researcher Honored with Hispanic STEM Award - News Releases | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Researcher Honored with Hispanic STEM Award Santiago Grijalva will direct grid research portfolio for NREL's Energy System Integration Facility October 24, 2013 A national organization devoted to getting more Hispanics into the fields of science, technology, engineering, and math (STEM), has honored a scientist at the Energy Department's National Renewable Energy Laboratory (NREL) with its annual Outstanding Technical Achievement Award. Santiago Carlos Grijalva is NREL's new director of the

  5. Students learn STEM leadership skills at Space Center | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration Students learn STEM leadership skills at Space Center Wednesday, March 25, 2015 - 11:26am NNSA Blog Three children of NNSA's National Security Campus employees were among 300 students from 39 countries selected to attend the Honeywell Leadership Challenge Academy. The scholarship program uses interactive technology and science-oriented workshops and team exercises to teach students leadership skills in science, technology, engineering and math (STEM). Held at the U.S.

  6. Developmental Control of Lignification in Stems of Lowland Switchgrass

    Office of Scientific and Technical Information (OSTI)

    Variety Alamo and the Effects on Saccharification Efficiency (Journal Article) | SciTech Connect Developmental Control of Lignification in Stems of Lowland Switchgrass Variety Alamo and the Effects on Saccharification Efficiency Citation Details In-Document Search Title: Developmental Control of Lignification in Stems of Lowland Switchgrass Variety Alamo and the Effects on Saccharification Efficiency Authors: Hui,Shen ; Chunxiang,Fu ; Xirong,Xiao ; Tui,Ray ; Yuhong,Tang ; Zengyu,Wang ;

  7. Paducah Area Students See Opportunities in STEM | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Area Students See Opportunities in STEM Paducah Area Students See Opportunities in STEM May 28, 2015 - 12:00pm Addthis Darryl Pea of Fluor Paducah Deactivation Project demonstrates use of a wind-speed meter to a class at Carlisle County Middle School. Darryl Pea of Fluor Paducah Deactivation Project demonstrates use of a wind-speed meter to a class at Carlisle County Middle School. PADUCAH, Ky. - Encouraging student interest in pursuing careers in science, technology, engineering, and math

  8. EM Engages Students, Professionals in Popular Conference Focused on STEM

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Careers | Department of Energy Engages Students, Professionals in Popular Conference Focused on STEM Careers EM Engages Students, Professionals in Popular Conference Focused on STEM Careers February 26, 2015 - 12:00pm Addthis EM’s Human Capital and Corporate Services Acting Deputy Assistant Secretary Melody Bell talks with Michigan State University engineering student Harold Hill at the BEYA conference. EM's Human Capital and Corporate Services Acting Deputy Assistant Secretary Melody

  9. Catalog of gene expression in adult neural stem cells and their in vivo microenvironment

    SciTech Connect (OSTI)

    Williams, Cecilia; Wirta, Valtteri; Meletis, Konstantinos; Wikstroem, Lilian; Carlsson, Leif; Frisen, Jonas; Lundeberg, Joakim . E-mail: joakim.lundeberg@biotech.kth.se

    2006-06-10

    Stem cells generally reside in a stem cell microenvironment, where cues for self-renewal and differentiation are present. However, the genetic program underlying stem cell proliferation and multipotency is poorly understood. Transcriptome analysis of stem cells and their in vivo microenvironment is one way of uncovering the unique stemness properties and provides a framework for the elucidation of stem cell function. Here, we characterize the gene expression profile of the in vivo neural stem cell microenvironment in the lateral ventricle wall of adult mouse brain and of in vitro proliferating neural stem cells. We have also analyzed an Lhx2-expressing hematopoietic-stem-cell-like cell line in order to define the transcriptome of a well-characterized and pure cell population with stem cell characteristics. We report the generation, assembly and annotation of 50,792 high-quality 5'-end expressed sequence tag sequences. We further describe a shared expression of 1065 transcripts by all three stem cell libraries and a large overlap with previously published gene expression signatures for neural stem/progenitor cells and other multipotent stem cells. The sequences and cDNA clones obtained within this framework provide a comprehensive resource for the analysis of genes in adult stem cells that can accelerate future stem cell research.

  10. Energy Secretary Moniz, EPA Administrator McCarthy and World Bank President

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Kim to Keynote ARPA-E Energy Innovation Summit | Department of Energy Moniz, EPA Administrator McCarthy and World Bank President Kim to Keynote ARPA-E Energy Innovation Summit Energy Secretary Moniz, EPA Administrator McCarthy and World Bank President Kim to Keynote ARPA-E Energy Innovation Summit December 9, 2015 - 2:05pm Addthis News Media Contact (202) 586-0976 DOENews@hq.doe.gov WASHINGTON - The U.S. Department of Energy today announced that U.S. Energy Secretary Ernest Moniz, U.S.

  11. Extractive industries and sustainable development: an evaluation of World Bank Group experience

    SciTech Connect (OSTI)

    Andres Liebenthal; Roland Michelitsch; Ethel Tarazona

    2005-07-01

    How effectively has the World Bank Group assisted its clients in enhancing the contribution of the extractive industries to sustainable development? (Extractive industries include oil, gas, and mining of minerals including coals and metals.) This evaluation finds that with its global mandate and experience, comprehensive country development focus, and overarching mission to fight poverty, the World Bank Group is well positioned to help countries overcome the policy, institutional, and technical challenges that prevent them from transforming resource endowments into sustainable benefits. Furthermore, the World Bank Group's achievements are many. On the whole, its extractive industries projects have produced positive economic and financial results, though compliance with its environmental and social safeguards remains a challenge. Its research has broadened and deepened understanding of the causes for the disappointing performance of resource-rich countries. Its guidelines for the mitigation of adverse environmental and social impacts have been widely used and appreciated. More recently, it has begun to address the challenge of country governance with a variety of instruments. The World Bank Group can, however, do much to improve its performance in enhancing the extractive industry sector's contribution to sustainable development and poverty reduction. The report identifies three main areas for improvement - formulating an integrated strategy, strengthening implementation and engagement of stakeholders. 5 annexes.

  12. Intrepid Museum Hosts STEM Mentoring Café | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Intrepid Museum Hosts STEM Mentoring Café Intrepid Museum Hosts STEM Mentoring Café November 17, 2015 - 3:32pm Addthis Intrepid Museum Hosts STEM Mentoring Café By The Intrepid Sea, Air & Space Museum Middle school girls and other curious students had the chance to meet with role models in STEM fields at STEM Mentoring Café-a morning of "speed mentoring" hosted by the Intrepid Museum on Saturday, November 14. The STEM Mentoring Café series is an initiative established by the

  13. STEM Mentors Reach Nearly 300 Western Kentucky Sixth Graders | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy STEM Mentors Reach Nearly 300 Western Kentucky Sixth Graders STEM Mentors Reach Nearly 300 Western Kentucky Sixth Graders November 25, 2015 - 12:00pm Addthis David Curry (far right) teaches Ayden Mowery, Jake Miller, and Bella Presson (left to right) at Ballard County Middle School to read a pH strip to test water. David Curry (far right) teaches Ayden Mowery, Jake Miller, and Bella Presson (left to right) at Ballard County Middle School to read a pH strip to test water. Ken Davis

  14. STEM-ing the Tide | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM-ing the Tide STEM-ing the Tide September 29, 2010 - 4:29pm Addthis Ali Zaidi Special Assistant to the Secretary of Energy Yesterday, the MacArthur Foundation rolled out its latest class of "geniuses" - 23 Americans who stand out because of their creativity and enterprise. Each recipient of the honor (and the $500,000 prize) has made an extraordinary contribution. One of those recipients is Amir Abo-Shaeer, an engineer in the aerospace and telecommunications industries who decided

  15. Women in STEM: Making a Cleaner Future | OpenEI Community

    Open Energy Info (EERE)

    The U.S. Department of Energy put out this short inspirational video about Women in Science, Technology, Engineering, and Mathematics (STEM). WomenInSTEM: Making a Cleaner...

  16. Interagency Mentoring and STEM Open House a Success | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Interagency Mentoring and STEM Open House a Success Interagency Mentoring and STEM Open House a Success January 24, 2013 - 3:56pm Addthis Dr. Holdren, White House Office of Science and Technology Policy Director, speaks at the January 20, 2013 Interagency Mentoring and STEM Open House. Dr. Holdren, White House Office of Science and Technology Policy Director, speaks at the January 20, 2013 Interagency Mentoring and STEM Open House. Cheron Wicker Department of Transporation What does this mean

  17. Higher Education

    Broader source: Energy.gov [DOE]

    Students considering or planning for a career in a hydrogen- or fuel-cell-related field can use the resources below to read about available career opportunities, college programs that emphasis hydrogen and fuel cell research, and energy-related educational opportunities such as scholarships and internships.

  18. Methods and apparatuses using filter banks for multi-carrier spread-spectrum signals

    DOE Patents [OSTI]

    Moradi, Hussein; Farhang, Behrouz; Kutsche, Carl A

    2014-10-14

    A transmitter includes a synthesis filter bank to spread a data symbol to a plurality of frequencies by encoding the data symbol on each frequency, apply a common pulse-shaping filter, and apply gains to the frequencies such that a power level of each frequency is less than a noise level of other communication signals within the spectrum. Each frequency is modulated onto a different evenly spaced subcarrier. A demodulator in a receiver converts a radio frequency input to a spread-spectrum signal in a baseband. A matched filter filters the spread-spectrum signal with a common filter having characteristics matched to the synthesis filter bank in the transmitter by filtering each frequency to generate a sequence of narrow pulses. A carrier recovery unit generates control signals responsive to the sequence of narrow pulses suitable for generating a phase-locked loop between the demodulator, the matched filter, and the carrier recovery unit.

  19. Methods and apparatuses using filter banks for multi-carrier spread-spectrum signals

    DOE Patents [OSTI]

    Moradi, Hussein; Farhang, Behrouz; Kutsche, Carl A

    2014-05-20

    A transmitter includes a synthesis filter bank to spread a data symbol to a plurality of frequencies by encoding the data symbol on each frequency, apply a common pulse-shaping filter, and apply gains to the frequencies such that a power level of each frequency is less than a noise level of other communication signals within the spectrum. Each frequency is modulated onto a different evenly spaced subcarrier. A demodulator in a receiver converts a radio frequency input to a spread-spectrum signal in a baseband. A matched filter filters the spread-spectrum signal with a common filter having characteristics matched to the synthesis filter bank in the transmitter by filtering each frequency to generate a sequence of narrow pulses. A carrier recovery unit generates control signals responsive to the sequence of narrow pulses suitable for generating a phase-locked loop between the demodulator, the matched filter, and the carrier recovery unit.

  20. The Protein Data Bank in Europe (PDBe): bringing structure to biology

    SciTech Connect (OSTI)

    Velankar, Sameer; Kleywegt, Gerard J.

    2011-04-01

    Some future challenges for the PDB and its guardians are discussed and current and future activities in structural bioinformatics at the Protein Data Bank in Europe (PDBe) are described. The Protein Data Bank in Europe (PDBe) is the European partner in the Worldwide PDB and as such handles depositions of X-ray, NMR and EM data and structure models. PDBe also provides advanced bioinformatics services based on data from the PDB and related resources. Some of the challenges facing the PDB and its guardians are discussed, as well as some of the areas on which PDBe activities will focus in the future (advanced services, ligands, integration, validation and experimental data). Finally, some recent developments at PDBe are described.

  1. Inspiring Girls to Explore STEM Careers in Charleston, SC

    Broader source: Energy.gov [DOE]

    Space and Naval Warfare Systems Center Atlantic (SSC Atlantic) partnered with the College of Charleston and Trident Technical College to get girls excited about Science, Technology, Engineering and Mathematics (STEM) at a Girls Day Out Summer Camp July 25-26.

  2. Employees share the fun of STEM at local elementary

    Broader source: Energy.gov [DOE]

    Employees from the U.S. Department of Energy’s (DOE) Oak Ridge Office of Environmental Management participated in Woodland Elementary’s Science, Technology, Engineering, and Math (STEM) night. Employees volunteered to help students from kindergarten through fourth grade forge a love for math and science and realize the possibilities these disciplines offer.

  3. Energy in Europe and Central Asia: A sector strategy for the World Bank Group

    SciTech Connect (OSTI)

    1998-12-31

    Many countries in the Europe and Central Asia region have had an excess production capacity, lower quality supply, decreasing demand, and inefficient consumption in the energy sector since the late 1980s. This report outlines the four main objectives that form the World Bank Group`s strategy for reform: assisting governments to protect the public interest, supporting economic transition, facilitating private investments, and promoting regional initiatives to increase energy trade.

  4. Clean energy for development investment framework: the World Bank Group action plan

    SciTech Connect (OSTI)

    2007-03-06

    In September 2005 the Development Committee requested the World Bank to develop an Investment Framework for Clean Energy and Development - in the context of the Gleneagles Communique on Climate Change, Clean Energy and Sustainable Development which was issued in July 2005. This Action Plan provides an update of work undertaken to date as well as actions planned by the World Bank Group (WBG) in support of the Clean Energy for Development Investment Framework (CEIF). The Action Plan relies on partnerships, including with the International Financial Institutions (IFIs) and the private sector. While it concentrates on maximizing and extending existing instruments, it provides for continued dialogue with governments and the private sector on new approaches to accelerate the transition to a low carbon economy. In addition to increased investments, the private sector has an important role to play in closing the investment gap in many countries. Projects such as Bujagali (Uganda), Nam Theun II (Laos) and China and India Thermal Power Plant Rehabilitation projects are examples of how partnerships with the private sector can work, both on financing but also on enhancing the overall regulatory framework for enhanced partnerships. The report was prepared for the 15 April 2007 Development Committee meeting, a joint committee of the Board of Governors of the World Bank and the International Monetary Fund on the transfer of real resources to developing countries. 3 figs., 3 tabs., 5 annexes.

  5. Slope and bank erosional stability of the Canonsburg, Pennsylvania, UMTRA disposal site

    SciTech Connect (OSTI)

    Not Available

    1994-12-01

    This report was prepared in response to US Nuclear Regulatory Commission (NRC) comments received in a letter of 8 March 1994. This letter included discussions of the US Department of Energy (DOE) 21 May 1993 geomorphic report for the Canonsburg, Pennsylvania, site. To clarify the NRC`s position, a DOE/NRC conference call was held on 12 April 1994. The NRC clarified that it did not require a preliminary erosion protection design for the Canonsburg site, but directed the DOE to address a ``one-bad-year`` scenario. The NRC wants confirmation that one bad year of stream flooding and landsliding will not release residual radioactive material (RRM) from the Canonsburg site into the creek. The NRC is concerned that a bad year theoretically could occur between postcell-closure inspections. These annual inspections are conducted in September or October. The NRC suggested that the following procedures should be conducted in this analysis: a flooding analysis, including the maximum saturation levels (flood water elevations) anticipated during a 100-year flood; a stream bank erosion analysis to determine how much of the bank adjacent to the site may be removed in a bad year; a slope stability analysis to determine how far back the site would be disturbed by slope instability that could be triggered by a bad year of stream bank erosion; and a ``critical cross section`` study to show the relationship of the RRM located outside the disposal cell to the maximum computer estimated erosion/landslide activity.

  6. Tube bank wastage in the Grimethorpe pressurized fluidized-bed combustor

    SciTech Connect (OSTI)

    Not Available

    1987-04-01

    The coal-fired pressurized fluidized bed combustion (PFBC) at Grimethorpe, England, was run for over 3600 hours of combustion testing under the joint sponsorship of the governments of the Federal Republic of Germany, the United Kingdom, and the US. Early in the course of these tests, significant metal wastage was experienced, especially on the inbed heat transfer tubes. This paper describes the modifications to design and new alloys which were tested in the PFBC. Operating conditions for three tube banks are given. A new tube bank, D, has been designed which incorporates a variety of alloy types, a number of tubes designed to operate at higher temperatures than those typical of the rest of the tube bank, and some tubes fitted with fins. The datum fluidizing velocity has been reduced to 0.8 m/sec. The effects of these variables: metal surface temperature, alloy chromium content, fin or stud arrangements, and fluidizing velocity, will be investigated in a continuing program funded by British Coal and the Central Electricity Generating Board of the UK, with some participation from the US Department of Energy and the Electric Power Research Institute. 3 references, 5 figures, 1 table.

  7. Incident report. Tube Bank C-metal wastage status report, November 1982

    SciTech Connect (OSTI)

    Not Available

    1982-11-01

    During the Hot Commissioning tests in preparation for Test Series 2, a significant degree of metal wastage occurred on the external surfaces of Tube Bank 'C'. The extent of the metal wastage was unexpected and has been a matter of concern to the Project. The report provides a history of the operational period for Tube Bank 'C' and details the measurements of metal wastage that have been recorded. The project has initiated an extensive study of the possible cause, or causes, of the metal wastage and these are discussed. Operational tests are to be carried out at Grimethorpe, CURL and CRE with a view to determining the mechanism of metal wastage that exists within the fluidized bed. The results of these tests will be reported and will form the basis for the design of a new bank, which will be installed in the combustor in due course, if required. The Project is taking necessary steps to ensure that the cause of the metal wastage is fully investigated and that the resultant slippage in the Test Series 2 schedule is minimised.

  8. Got Questions about Women in Science, Tech, Engineering, or Math (STEM)?

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Tweet us! | Department of Energy Got Questions about Women in Science, Tech, Engineering, or Math (STEM)? Tweet us! Got Questions about Women in Science, Tech, Engineering, or Math (STEM)? Tweet us! March 15, 2012 - 3:26pm Q&A What questions do you have for the experts during our Women in STEM Tweet Up? Ask Us Addthis Join us for a conversation about women in science, technology, engineering, and Math (STEM) on Twitter on Thursday, March 22 at 2:30pm EDT by following the hashtag #STEM.

  9. ORAU Science Education Program (SEP) Global Change Education...

    Energy Savers [EERE]

    ORAU Science Education Program (SEP) Global Change Education Program (GCEP) PIA, Office of Information Resources ORAU Science Education Program (SEP) Global Change Education...

  10. ORAU Science Education Program (SEP) Global Change Education...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ORAU Science Education Program (SEP) Global Change Education Program (GCEP) PIA, Office of Information Resources ORAU Science Education Program (SEP) Global Change Education ...

  11. Shannon Greco: a self-described "STEM education zealot" | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Shannon Brescher Shea About Us Shannon Brescher Shea - Communications Manager, Clean Cities Program Shannon Brescher Shea is the communications manager for Clean Cities, the deployment area of the Vehicle Technologies Office in the Office of Energy Efficiency and Renewable Energy. She directs Clean Cities' printed and online materials, media relations, outreach events, and communications strategy and messaging. In 2008, Shannon began at the Energy Department as a Presidential Management Fellow

  12. Three NNSA researchers receive President's highest early-career STEM

    National Nuclear Security Administration (NNSA)

    award | National Nuclear Security Administration Three NNSA researchers receive President's highest early-career STEM award Thursday, May 5, 2016 - 10:35am Secretary of Energy Ernest Moniz, left, and NNSA Administrator Frank Klotz, right, join physicist Tammy Ma as she celebrates receiving a PECASE award for her work with the National Ignition Facility. Yesterday Secretary of Energy Ernest Moniz hosted a special ceremony honoring DOE's 13 recipients of the 2016 Presidential Early Career

  13. Radiation-Induced Notch Signaling in Breast Cancer Stem Cells

    SciTech Connect (OSTI)

    Lagadec, Chann; Vlashi, Erina; Alhiyari, Yazeed; Phillips, Tiffany M.; Bochkur Dratver, Milana; Pajonk, Frank

    2013-11-01

    Purpose: To explore patterns of Notch receptor and ligand expression in response to radiation that could be crucial in defining optimal dosing schemes for ?-secretase inhibitors if combined with radiation. Methods and Materials: Using MCF-7 and T47D breast cancer cell lines, we used real-time reverse transcriptionpolymerase chain reaction to study the Notch pathway in response to radiation. Results: We show that Notch receptor and ligand expression during the first 48 hours after irradiation followed a complex radiation dosedependent pattern and was most pronounced in mammospheres, enriched for breast cancer stem cells. Additionally, radiation activated the Notch pathway. Treatment with a ?-secretase inhibitor prevented radiation-induced Notch family gene expression and led to a significant reduction in the size of the breast cancer stem cell pool. Conclusions: Our results indicate that, if combined with radiation, ?-secretase inhibitors may prevent up-regulation of Notch receptor and ligand family members and thus reduce the number of surviving breast cancer stem cells.

  14. Regional geology of Georges Bank basin - OCS Sale 42 drilling results

    SciTech Connect (OSTI)

    High, L.R. Jr.

    1985-02-01

    Industry bid aggressively in OCS Sale 42, spending $816 million. Eight wildcats were drilled in 1981-82 to test 5 major plays. All wells were dry; no potential reservoir or source rocks were found. The tectonic-stratigraphic framework of the Georges Bank basin is that of an Atlantic-type plate margin. Two major unconformities divide the section into prerift, synrift, and postrift sequences. The prerift sequence consists of Paleozoic metasediments in basement fault blocks. Synrift sediments consist of Newark Group equivalents: the Argo Salt and the Iroquoi Formation. The postrift sequence consists of Mohican red beds overlain by progradational wedges, with the carbonate Abenaki Formation at the base. The objective in 4 of the 8 wildcats was the Iroquois Formation. Mobil 312-1 and Shell 357-1 were drilled into a seismic anomaly interpreted to be a reef. This structure was found to be a complex carbonate mound. Exxon 975-1 was drilled on a seismic amplitude anomaly variously interpreted to be the result of salt, coal, or porous carbonates. This anomaly proved to be caused by a salt bed. The objective in Shell 410-1R was carbonate banks over a basement horst block. No significant zones of porosity were found. The remaining 4 wildcats were drilled on Abenaki prospects. Mobil 273-1, Tenneco 187-1d, and Conoco 145-1 were drilled for possible carbonate banks over a salt structure. Only thin oolitic grainstone intervals were found. Exxon 133-1 was based on a seismic anomaly interpreted to be a patch reef. This feature was found to be a volcanic cone.

  15. The green bank northern celestial cap pulsar survey. I. Survey description, data analysis, and initial results

    SciTech Connect (OSTI)

    Stovall, K.; Dartez, L. P.; Ford, A. J.; Garcia, A.; Hinojosa, J.; Jenet, F. A.; Leake, S.; Lynch, R. S.; Archibald, A. M.; Karako-Argaman, C.; Kaspi, V. M.; Ransom, S. M.; Banaszak, S.; Biwer, C. M.; Day, D.; Flanigan, J.; Kaplan, D. L.; Boyles, J.; Hessels, J. W. T.; Kondratiev, V. I.; and others

    2014-08-10

    We describe an ongoing search for pulsars and dispersed pulses of radio emission, such as those from rotating radio transients (RRATs) and fast radio bursts, at 350 MHz using the Green Bank Telescope. With the Green Bank Ultimate Pulsar Processing Instrument, we record 100 MHz of bandwidth divided into 4096 channels every 81.92 μs. This survey will cover the entire sky visible to the Green Bank Telescope (δ > –40°, or 82% of the sky) and outside of the Galactic Plane will be sensitive enough to detect slow pulsars and low dispersion measure (<30 pc cm{sup –3}) millisecond pulsars (MSPs) with a 0.08 duty cycle down to 1.1 mJy. For pulsars with a spectral index of –1.6, we will be 2.5 times more sensitive than previous and ongoing surveys over much of our survey region. Here we describe the survey, the data analysis pipeline, initial discovery parameters for 62 pulsars, and timing solutions for 5 new pulsars. PSR J0214+5222 is an MSP in a long-period (512 days) orbit and has an optical counterpart identified in archival data. PSR J0636+5129 is an MSP in a very short-period (96 minutes) orbit with a very low mass companion (8 M{sub J}). PSR J0645+5158 is an isolated MSP with a timing residual RMS of 500 ns and has been added to pulsar timing array experiments. PSR J1434+7257 is an isolated, intermediate-period pulsar that has been partially recycled. PSR J1816+4510 is an eclipsing MSP in a short-period orbit (8.7 hr) and may have recently completed its spin-up phase.

  16. Speakers: Adam Sieminski, Deutsche Bank Stephen P. A. Brown, Resources for the Future

    U.S. Energy Information Administration (EIA) Indexed Site

    5: "Energy and the Economy" Speakers: Adam Sieminski, Deutsche Bank Stephen P. A. Brown, Resources for the Future Donald L. Paul, University of Southern California Energy Institute David Sandalow, DOE Christof Rühl, Group Chief Economist, BP [Note: Recorders did not pick up introduction of panel (see biographies for details on the panelists) or introduction of session.] Adam: Microphone. So, we've lost a little bit of time because of all of the sessions running a bit over, but here is

  17. Low jitter spark gap switch for repetitively pulsed parallel capacitor banks

    SciTech Connect (OSTI)

    Rohwein, G. J.

    1980-01-01

    A two-section air insulated spark gap has been developed for switching multi-kilojoule plus-minus charged parallel capacitor banks which operate continuously at pulse rates up to 20 pps. The switch operates with less than 2 ns jitter, recovers its dielectric strength within 2 to 5 ms and has not shown degraded performance in sequential test runs totaling over a million shots. Its estimated life with copper electrodes is > 10/sup 7/ shots. All preliminary tests indicate that the switch is suitable for continuous running multi-kilojoule systems operating to at least 20 pps.

  18. Tube bank metal wastage in the Grimethorpe PFBC. [Pressurized fluidized-bed combustor

    SciTech Connect (OSTI)

    Not Available

    1984-02-01

    The 2 m x 2 m PFBC facility at Grimethorpe, England is designed to explore the pressurized fluidized-bed combustion of coal over a wide range of conditions. A significant degree of metal wastage was observed on the fireside surfaces of the tube bank which occurred during 468 coal-burning hours of hot shakedown and hot commissioning testing. This paper described the operating conditions during testing, the erosion of the metal surfaces, and the repair and modifications undertaken. 1 reference, 4 figures, 2 tables.

  19. National Energy Education Summit

    Broader source: Energy.gov [DOE]

    The National Energy Education Summit is organized by the Council of Energy Research and Education Leaders (CEREL) and will serve as a first-of-its-kind national forum for energy educators, subject...

  20. ORISE: Science Education Events

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Education Events Science Education Events Recognizing that vast improvements in science, technology, engineering and math are key to innovation and economic growth, the Oak Ridge Institute for Science and Education (ORISE) manages high-profile local and national education and research initiatives. For example, scholarly competitions, summer education workshops and teacher professional development programs create excitement and inspire educators and students to pursue interests in

  1. Join the STEM and Mentoring Interagency Open House Friday, January...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    In honor of National Mentoring Month and the 57th Presidential Inauguration, the Departments of Energy, Transportation, Labor, Education, National Science Foundation, Environmental ...

  2. Front and Center: Bringing Marginalized Girls into Focus in STEM...

    Office of Environmental Management (EM)

    and Girls, the Department of Education, and the Georgetown University Law Center on Poverty and Inequality highlighted programs that focus on developing the talent of girls of ...

  3. NREL: Education Center - Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Center Printable Version Programs NREL's Education Center in Golden, Colorado, offers a variety of program topics and experiences for students and adult groups addressing...

  4. Energy Education | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy Education Learn how NREL's Workforce Development and Education Programs inspire students, teachers, and executives to explore sustainable energy solutions to meet our future...

  5. Education | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education Education Students learn about solar energy. DOE supports demonstrations and commercialization by providing technically accurate and objective information to key target ...

  6. The Department of Energy Hosts Its First STEM in Indian Country Roundtable

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Series | Department of Energy The Department of Energy Hosts Its First STEM in Indian Country Roundtable Series The Department of Energy Hosts Its First STEM in Indian Country Roundtable Series April 13, 2015 - 9:22am Addthis The Department of Energy Hosts Its First STEM in Indian Country Roundtable Series In December 2014, the U.S. Department of Energy (DOE) Secretary, Ernest Moniz, met with Departmental Tribal Advisory Groups in Phoenix, Arizona. During the meeting, many tribal leaders

  7. YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead-dependent manner

    SciTech Connect (OSTI)

    Han, Dasol; Byun, Sung-Hyun; Park, Soojeong; Kim, Juwan; Kim, Inhee; Ha, Soobong; Kwon, Mookwang; Yoon, Keejung

    2015-02-27

    Mammalian brain development is regulated by multiple signaling pathways controlling cell proliferation, migration and differentiation. Here we show that YAP/TAZ enhance embryonic neural stem cell characteristics in a cell autonomous fashion using diverse experimental approaches. Introduction of retroviral vectors expressing YAP or TAZ into the mouse embryonic brain induced cell localization in the ventricular zone (VZ), which is the embryonic neural stem cell niche. This change in cell distribution in the cortical layer is due to the increased stemness of infected cells; YAP-expressing cells were colabeled with Sox2, a neural stem cell marker, and YAP/TAZ increased the frequency and size of neurospheres, indicating enhanced self-renewal- and proliferative ability of neural stem cells. These effects appear to be TEA domain family transcription factor (Tead)–dependent; a Tead binding-defective YAP mutant lost the ability to promote neural stem cell characteristics. Consistently, in utero gene transfer of a constitutively active form of Tead2 (Tead2-VP16) recapitulated all the features of YAP/TAZ overexpression, and dominant negative Tead2-EnR resulted in marked cell exit from the VZ toward outer cortical layers. Taken together, these results indicate that the Tead-dependent YAP/TAZ signaling pathway plays important roles in neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development. - Highlights: • Roles of YAP and Tead in vivo during mammalian brain development are clarified. • Expression of YAP promotes embryonic neural stem cell characteristics in vivo in a cell autonomous fashion. • Enhancement of neural stem cell characteristics by YAP depends on Tead. • Transcriptionally active form of Tead alone can recapitulate the effects of YAP. • Transcriptionally repressive form of Tead severely reduces stem cell characteristics.

  8. The STEM Promise: Opportunities for Economic Empowerment. Join the Conversation on April 8.

    Broader source: Energy.gov [DOE]

    To learn more about the potential of STEM careers to ease the gender pay gap and pathways into STEM careers for entry-level opportunities, the YWCA and the Department of Energy are teaming up to host a panel and Tweet Up on The STEM Promise: Opportunities for Economic Empowerment. On April 8, 2014, from 3-4pm EST, follow along on #STEMEqualPay to join the conversation.

  9. Statement of Secretary Steven Chu on President Obama's Decision on Stem

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cell Research | Department of Energy President Obama's Decision on Stem Cell Research Statement of Secretary Steven Chu on President Obama's Decision on Stem Cell Research March 9, 2009 - 12:00am Addthis Washington, DC - Energy Secretary Steven Chu made the following statement regarding President Obama's decision to allow promising stem cell research to go forward under strict ethical guidelines: "One of the reasons I joined President Obama's cabinet was his commitment to making

  10. Design, fabrication, and integration testing of the Garden Banks 388 subsea production template

    SciTech Connect (OSTI)

    Ledbetter, W.R.; Smith, D.W.; Pierce, D.M.; Padilla, J.R.

    1995-12-31

    Enserch Exploration`s Garden Banks 388 development has a production scheme based around a floating drilling and production facility and subsea drilling/production template. The Floating Production Facility (FPF) is a converted semisubmersible drilling rig that will drill and produce through a 24-well slot subsea template. This development is located in Block 388 of the Garden Banks area in the Gulf of Mexico approximately 200 miles southwest of New Orleans, Louisiana. The production system is being installed in an area of known oil and gas reserves and will produce to a shallow water platform 54 miles away at Eugene Island 315. The FPF will be permanently moored above the template. The subsea template has been installed in 2190 feet of water and will produce through a 2,000 foot free-standing production riser system to the FPF. The produced fluids are partially separated on the FPF before oil and gas are pumped through the template to export gathering lines that are connected to the shallow water facility. The system designed through-put is 40,000 BOPD of oil and 120 MMSCFD of gas.

  11. STEM Middle School Mentoring Cafés Take it on the Road | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy STEM Middle School Mentoring Cafés Take it on the Road STEM Middle School Mentoring Cafés Take it on the Road November 12, 2015 - 3:00pm Addthis STEM Mentoring Cafes - sponsored in part by the Energy Department - engage middle schoolers with science and technology professionals at local science centers and museums nationwide to inspire them to learn about a broad spectrum of energy-related career fields. source: Matty Greene/US DOE STEM Mentoring Cafes - sponsored in part by the

  12. Let's Keep Talking: Women in STEM Tweet Up | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Let's Keep Talking: Women in STEM Tweet Up Let's Keep Talking: Women in STEM Tweet Up April 11, 2012 - 2:37pm Addthis The Energy Department's Dr. Karina Edmonds and Erin Pierce talk to thousands as part of the Women in STEM Tweet Up on March 22, 2012. | Photo credit: Quentin Kruger | Energy Department file photo The Energy Department's Dr. Karina Edmonds and Erin Pierce talk to thousands as part of the Women in STEM Tweet Up on March 22, 2012. | Photo credit: Quentin Kruger | Energy Department

  13. Bringing Students to STEM with My Brother's Keeper | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bringing Students to STEM with My Brother's Keeper Bringing Students to STEM with My Brother's Keeper February 29, 2016 - 9:41am Addthis A student from from Chicago's Laura S. Ward STEM School learns to use computational thinking during <a href="http://www.anl.gov/articles/inspiring-next-generation-computational-thinkers">My Brother's Keeper's visit to Argonne National Lab.</a> | Photo Courtesy of Argonne National Lab. A student from from Chicago's Laura S. Ward STEM School

  14. New Energy.gov Video Series Highlights Women in STEM Fields | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Energy.gov Video Series Highlights Women in STEM Fields New Energy.gov Video Series Highlights Women in STEM Fields January 14, 2014 - 9:55am Addthis Carter Wall, a STEM professional and ambassador for the Energy Department's Women in Clean Energy Initiative, is the first profile in our new #WomeninSTEM video series. | Video by Matty Greene. Erin R. Pierce Erin R. Pierce Former Digital Communications Specialist, Office of Public Affairs Matty Greene Matty Greene Former Videographer

  15. Deploying Federal Talent to Build the Future STEM Workforce | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Deploying Federal Talent to Build the Future STEM Workforce Deploying Federal Talent to Build the Future STEM Workforce February 10, 2014 - 11:14am Addthis Federal employees from all agencies were invited to attend the First Annual STEM Volunteer Fair at the Department of Energy on February 5, 2014, hosted by the Office of Economic Impact and Diversity. I Photo by Matty Greene, U.S. Department of Energy Federal employees from all agencies were invited to attend the First Annual STEM

  16. Resources: Women and Girls in STEM Programs at the Energy Department

    Office of Energy Efficiency and Renewable Energy (EERE)

    Across the Energy Department, there are resources and program available to expand STEM - that's science, technology, engineering, and mathematics - to the next generation to ready our nation's...

  17. NETL Researcher Honored with 2014 FLC Mid-Atlantic Regional STEM...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    high school and middle school students throughout West Virginia, putting the pursuit of STEM careers within the reach of students. Dr. Gerdes is a researcher at NETL, studying...

  18. Young Women's Conference cheers on girls interested in STEM | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab Young Women's Conference cheers on girls interested in STEM By Jeanne Jackson DeVoe March 27, 2014 Tweet Widget Google Plus One Share on Facebook PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's Conference on March 21 at Princeton University. (Photo by Elle Starkman/ PPPL Office of Communications) PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's

  19. Young Women's Conference cheers on girls interested in STEM | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab Young Women's Conference cheers on girls interested in STEM By Jeanne Jackson DeVoe March 28, 2014 Tweet Widget Google Plus One Share on Facebook PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's Conference on March 21. (Photo by Elle Starkman/ PPPL Office of Communications) PPPL engineer Han Zhang shows off a plasma ball to a few of the 400 young women who attended PPPL's Young Women's Conference on March 21.

  20. NREL: Workforce Development and Education Programs - Students Grade 4-12

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Students Grade 4-12 NREL's Workforce Development and Education Programs seek to promote science, technology, engineering, and mathematics (STEM) using renewable energy as the vehicle to capture student interest. Engaging students in science and engineering activities opens the door for both study and career opportunities in these disciplines. Students from traditionally under represented ethnic and gender groups are encouraged to participate from all academic levels. Elementary Several

  1. Living in a Materials World: Materials Science Engineering Professional Development for K-12 Educators

    SciTech Connect (OSTI)

    Anne Seifert; Louis Nadelson

    2011-06-01

    Advances in materials science are fundamental to technological developments and have broad societal impacs. For example, a cellular phone is composed of a polymer case, liquid crystal displays, LEDs, silicon chips, Ni-Cd batteries, resistors, capacitors, speakers, microphones all of which have required advances in materials science to be compacted into a phone which is typically smaller than a deck of cards. Like many technological developments, cellular phones have become a ubiquitous part of society, and yet most people know little about the materials science associated with their manufacture. The probable condition of constrained knowledge of materials science was the motivation for developing and offering a 20 hour fourday course called 'Living in a Materials World.' In addition, materials science provides a connection between our every day experiences and the work of scientists and engineers. The course was offered as part of a larger K-12 teacher professional development project and was a component of a week-long summer institute designed specifically for upper elementary and middle school teachers which included 20 hour content strands, and 12 hours of plenary sessions, planning, and collaborative sharing. The focus of the institute was on enhancing teacher content knowledge in STEM, their capacity for teaching using inquiry, their comfort and positive attitudes toward teaching STEM, their knowledge of how people learn, and strategies for integrating STEM throughout the curriculum. In addition to the summer institute the participating teachers were provided with a kit of about $300 worth of materials and equipment to use to implement the content they learned in their classrooms. As part of this professional development project the participants were required to design and implement 5 lesson plans with their students this fall and report on the results, as part of the continuing education course associated with the project. 'Living in a Materials World' was one of the fifteen content strands offered at the institute. The summer institute participants were pre/post tested on their comfort with STEM, their perceptions of STEM education, their pedagogical discontentment, their implementations of inquiry, their attitudes toward student learning of STEM, and their content knowledge associated with their specific content strand. The results from our research indicate a significant increase in content knowledge (t = 11.36, p < .01) for the Living in a Materials World strand participants. Overall the summer institute participants were found to have significant increases in their comfort levels for teaching STEM (t = 10.94, p < .01), in inquiry implementation (t = 5.72, p < .01) and efficacy for teaching STEM (t = 6.27, p < .01) and significant decrease in pedagogical discontentment (t = -6.26, p < .01).

  2. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    April 8, 2003 [Education] ARM Education Team Attends 2003 ARM Science Team Meeting Bookmark and Share Members of the ARM Education team attended the 2003 ARM Science Team Meeting. Fairley Barnes, Carrie Talus, Mike Ebinger, and Jeff Berger (of Yaza Design) participated in this year's meeting. They presented a poster entitled "Traditional Ecological Knowledge as a Tool for Science Education and Public Outreach" (PowerPoint file) and the latest version of the ARM Education climate change

  3. Radiation Therapy Oncology Group Translational Research Program Stem Cell Symposium: Incorporating Stem Cell Hypotheses into Clinical Trials

    SciTech Connect (OSTI)

    Woodward, Wendy A. Bristow, Robert G.; Clarke, Michael F.; Coppes, Robert P.; Cristofanilli, Massimo; Duda, Dan G.; Fike, John R.; Hambardzumyan, Dolores; Hill, Richard P.; Jordan, Craig T.; Milas, Luka; Pajonk, Frank; Curran, Walter J.; Dicker, Adam P.; Chen Yuhchyau

    2009-08-01

    At a meeting of the Translation Research Program of the Radiation Therapy Oncology Group held in early 2008, attendees focused on updating the current state of knowledge in cancer stem cell research and discussing ways in which this knowledge can be translated into clinical use across all disease sites. This report summarizes the major topics discussed and the future directions that research should take. Major conclusions of the symposium were that the flow cytometry of multiple markers in fresh tissue would remain the standard technique of evaluating cancer-initiating cells and that surrogates need to be developed for both experimental and clinical use.

  4. Introducing the All-Star Geeks of SoSTEM 2014!

    Broader source: Energy.gov [DOE]

    Some of America’s top STEM doers, innovators, and thinkers will continue the celebration of all things STEM on the day after State of the Union, by participating in the second annual State of Science, Technology, Engineering, and Math (“SoSTEM”) event at the White House. Tune in at www.whitehouse.gov/live at 10am EST to watch.

  5. Longitudinal Bank for Serum, Plasma and DNA for Detection of Biomarkers

    SciTech Connect (OSTI)

    Ward, David C

    2009-07-20

    With the support of this DOE appropriation, NVCI has established a biorepository for serum, plasma, DNA and urine specimens. Over 2,500 patients have been consented which is over 90% of all new patients seen at NVCI. The specimens have been coded, centrifuged, aliquoted and frozen at -80?C in a rapid manner so that they are all processed in less than 1 hour from the acquisition. There are over 28,000 aliquoted, coded tubes in our inventory. Specimens from 200 control volunteer subjects without any history of cancer also have been banked. The patient specimens are encoded and the demographics and therapeutic treatments are linked to the Oncore software. This computer program catalogues the specimens and provides a rapid conduit between the biorepository and the NVCI electronic medical record.

  6. Longitudinal Bank for Serum, Plasma, and DNA for Detection of Biomarkers

    SciTech Connect (OSTI)

    Vogelzang, Nicolas; Fink, Louis

    2007-11-12

    The discovery of genetic or biochemical markers to discriminate malignant cancers from normal or benign disease states, markers to stage cancer or monitor disease progression and markers that provide an early indication of an individuals response to chemotherapy have become a major research objectives of the oncology community over the past few years. The goal of the project is to create a patient speciment bank of serum, plasma, urine and tissues from approximately 1500 individuals. The collection of samples from individuals on a longitudinal basis provided proteomic and biochemical data to be correlated with clinical endpoints. This greatly enhanced our ability to identify biiomarkers for staging different cancers and to detect patient responsiveness to therapy at an early state in the treatment process.

  7. Application of STEM Characterization for Investigating Radiation Effects in BCC Fe-Based Alloys

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Parish, Chad M; Field, Kevin G; Certain, Alicia; Wharry, Janelle P.

    2015-01-01

    This paper provides an overview of advanced scanning transmission electron microscopy (STEM) techniques used for characterization of irradiated BCC Fe-based alloys. Advanced STEM methods provide the high-resolution imaging and chemical analysis necessary to understand the irradiation response of BCC Fe-based alloys. The use of STEM with energy dispersive X-ray spectroscopy (EDX) for measurement of radiation-induced segregation (RIS) is described, with an illustrated example of RIS in proton- and self-ion irradiated T91. Aberration-corrected STEM-EDX for nanocluster/nanoparticle imaging and chemical analysis is also discussed, and examples are provided from ion-irradiated oxide dispersion strengthened (ODS) alloys. Finally, STEM techniques for void, cavity, andmore » dislocation loop imaging are described, with examples from various BCC Fe-based alloys.« less

  8. ORAU Science Education Program (SEP) Global Change Education Program (GCEP)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PIA, Office of Information Resources | Department of Energy ORAU Science Education Program (SEP) Global Change Education Program (GCEP) PIA, Office of Information Resources ORAU Science Education Program (SEP) Global Change Education Program (GCEP) PIA, Office of Information Resources ORAU Science Education Program (SEP) Global Change Education Program (GCEP) PIA, Office of Information Resources PDF icon ORAU Science Education Program (SEP) Global Change Education Program (GCEP) PIA, Office

  9. GATA-1 directly regulates Nanog in mouse embryonic stem cells

    SciTech Connect (OSTI)

    Li, Wen-Zhong; Ai, Zhi-Ying; Wang, Zhi-Wei; Chen, Lin-Lin; Guo, Ze-Kun; Zhang, Yong

    2015-09-25

    Nanog safeguards pluripotency in mouse embryonic stem cells (mESCs). Insight into the regulation of Nanog is important for a better understanding of the molecular mechanisms that control pluripotency of mESCs. In a silico analysis, we identify four GATA-1 putative binding sites in Nanog proximal promoter. The Nanog promoter activity can be significantly repressed by ectopic expression of GATA-1 evidenced by a promoter reporter assay. Mutation studies reveal that one of the four putative binding sites counts for GATA-1 repressing Nanog promoter activity. Direct binding of GATA-1 on Nanog proximal promoter is confirmed by electrophoretic mobility shift assay and chromatin immunoprecipitation. Our data provide new insights into the expanded regulatory circuitry that coordinates Nanog expression. - Highlights: • The Nanog proximal promoter conceives functional element for GATA-1. • GATA-1 occupies the Nanog proximal promoter in vitro and in vivo. • GATA-1 transcriptionally suppresses Nanog.

  10. Fermilab Science Education Office

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Off or Not Supported in Your Browser. You can still access all of the content on the Education Server about Science Education, but turn on JavaScript to enable all this site's...

  11. Analytical SuperSTEM for extraterrestrial materials research

    SciTech Connect (OSTI)

    Bradley, J P; Dai, Z R

    2009-09-08

    Electron-beam studies of extraterrestrial materials with significantly improved spatial resolution, energy resolution and sensitivity are enabled using a 300 keV SuperSTEM scanning transmission electron microscope with a monochromator and two spherical aberration correctors. The improved technical capabilities enable analyses previously not possible. Mineral structures can be directly imaged and analyzed with single-atomic-column resolution, liquids and implanted gases can be detected, and UV-VIS optical properties can be measured. Detection limits for minor/trace elements in thin (<100 nm thick) specimens are improved such that quantitative measurements of some extend to the sub-500 ppm level. Electron energy-loss spectroscopy (EELS) can be carried out with 0.10-0.20 eV energy resolution and atomic-scale spatial resolution such that variations in oxidation state from one atomic column to another can be detected. Petrographic mapping is extended down to the atomic scale using energy-dispersive x-ray spectroscopy (EDS) and energy-filtered transmission electron microscopy (EFTEM) imaging. Technical capabilities and examples of the applications of SuperSTEM to extraterrestrial materials are presented, including the UV spectral properties and organic carbon K-edge fine structure of carbonaceous matter in interplanetary dust particles (IDPs), x-ray elemental maps showing the nanometer-scale distribution of carbon within GEMS (glass with embedded metal and sulfides), the first detection and quantification of trace Ti in GEMS using EDS, and detection of molecular H{sub 2}O in vesicles and implanted H{sub 2} and He in irradiated mineral and glass grains.

  12. UNIRIB: Education and Training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education and Training Education and Training The University Radioactive Ion Beam (UNIRIB) consortium provides education and training as part of its efforts to help the U.S. Department of Energy (DOE) build a highly-skilled, national, scientific workforce. UNIRIB provides a university atmosphere within the structure of a national laboratory. The on-site staff ensures dedicated support to consortium members performing research, as well as guide the training of educators and students-from

  13. NREL: Education Center - Events

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Center Printable Version Events Unless otherwise notified, events listed here will be held at the NREL Education Center, 15013 Denver West Parkway, Golden, CO. The Education Center phone number is 303-384-6565. June 2016 Sustainable NREL Walking Campus Tour June 17, 2016, 9:30 - 11:15 am Golden, CO Contact: NREL Education Center 303-384-6565 NREL exemplifies environmental sustainability throughout its operations. Visitors learn about renewable energy and energy efficiency research as

  14. ARM - Education and Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MaterialsEducation and Outreach Publications Journal Articles Conference Documents Program Documents Technical Reports Publications Database Public Information Materials Image...

  15. Energy Education Data Jam

    Broader source: Energy.gov [DOE]

    The challenge of the Energy Education Data Jam is to explore how the use of energy data, energy education content, and information technology can increase the nation’s—and, in particular, students’—understanding and decision-making related to energy use. This event will bring together developers, educators, and energy data experts to collaborate on the development of innovative energy education apps and visualizations to improve the energy literacy gap in the United States.

  16. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    July 8, 2007 [Education] Climate Research Facility in Papua New Guinea Launches Kiosk Bookmark and Share In 2004, ACRF Education and Outreach worked with Tradewind Communications to film interviews around Manus Island for the kiosk. The Climate Change: Science and Traditional Knowledge kiosk project for the ACRF Tropical Western Pacific sites has come full circle. Four years ago, ACRF Education and Outreach started building educational kiosks to promote awareness and understanding of ARM

  17. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    7, 2007 [Education] ACRF Education and Outreach Presents Women in Science Conference Bookmark and Share ACRF Education and Outreach staff attemded the Women In Science Conference at the Omniplex Science Museum. ACRF Education and Outreach staff presented information about the Atmospheric Radiation Measurement Program at the Women In Science Conference at the Omniplex Science Museum. The event was sponsored by the Oklahoma Experimental Program to Stimulate Competitive Research (OK-EPSCOR).

  18. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    6, 2006 [Education] Darwin Kiosk is Installed and Officially Launched Bookmark and Share ARM Education and Outreach installed an educational kiosk in the Museum and Art Gallery of the Northern Territory in Darwin, Australia. The Museum and Art Gallery of the Northern Territory is now home to the Climate Change: Science and Traditional Knowledge kiosk, developed by ARM Education and Outreach for the Darwin, Australia community. A crowd of about 50 people, including kiosk interviewees, museum

  19. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    January 31, 2005 [Education] Education and Outreach Program Visits Schools in the Tropics Bookmark and Share A native islander is interviewed in his natural setting at Manus Island as part of the TWP kiosk development effort. In September 2004, ARM Education and Outreach staff spent 23 days at the Tropical Western Pacific (TWP) locale to develop stronger working relationships with educators and administrators at each of the TWP sites-Manus Island, Nauru Island, and Darwin, Australia. While

  20. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    May 19, 2002 [Education] ARM Education Takes Part in International Digital Library Bookmark and Share The ARM Education team has recently completed writing a proposal to the National Science Foundation (NSF) International Digital Library (IDL) Program. This proposal titled, "An International Digital Library for Atmospheric Visualization" is a collaboration between the ARM Education Program at Los Alamos National Laboratory, Christopher Klaus at Argonne National Laboratory, Keith Andrew

  1. Banks Lake Fishery Evaluation Project Annual Report : Fiscal Year 2008 (March 1, 2008 to February 1, 2009).

    SciTech Connect (OSTI)

    Polacek, Matt

    2009-07-15

    The Washington Department of Fish and Wildlife implemented the Banks Lake Fishery Evaluation Project (BLFEP) in September 2001 with funds from the Bonneville Power Administration, and continued project tasks in 2008. The objective was to evaluate factors that could limit kokanee in Banks Lake, including water quality, prey availability, harvest, and acute predation during hatchery releases. Water quality parameters were collected twice monthly from March through November. Banks Lake water temperatures began to increase in May and stratification was apparent by July. By late August, the thermocline had dropped to 15 meters deep, with temperatures of 21-23 C in the epilimnion and 16-19 C in the hypolimnion. Dissolved oxygen levels were generally above 8 mg/L until August when they dropped near or below 5 mg/L deeper than 20-meters. Secchi depths ranged from 3.2 to 6.2 meters and varied spatially and temporally. Daphnia and copepod densities were the highest in May and June, reaching densities of 26 copepods/liter and 9 Daphnia/liter. Fish surveys were conducted in July and October 2008 using boat electrofishing, gill netting, and hydroacoustic surveys. Lake whitefish (71%) and yellow perch (16%) dominated the limnetic fish assemblage in the summer, while lake whitefish (46%) and walleye (22%) were the most abundant in gill net catch during the fall survey. Piscivore diets switched from crayfish prior to the release of rainbow trout to crayfish and rainbow trout following the release. The highest angling pressure occurred in May, when anglers were primarily targeting walleye and smallmouth bass. Boat anglers utilized Steamboat State Park more frequently than any other boat ramp on Banks Lake. Shore anglers used the rock jetty at Coulee City Park 45% of the time, with highest use occurring from November through April. Ice fishing occurred in January and February at the south end of the lake. An estimated total of 4,397 smallmouth bass, 11,106 walleye, 371 rainbow trout, and 509 yellow perch were harvested from Banks Lake in 2008. No kokanee were reported in the creel; however, local reports indicated that anglers were targeting and catching kokanee. The economic benefit of the Banks Lake fishery was estimated at $2,288,005 during 2008. Abundance estimates from the hydroacoustic survey in July were 514,435 lake whitefish and 10,662 kokanee, with an overall abundance estimate of 626,061 limnetic fish greater than 100 mm. When comparing spring fry, fall fingerling and yearling net pen release strategies of kokanee, 95% were of hatchery origin, with the highest recaptures coming from the fall fingerling release group.

  2. Energy Exchange Continuing Education Units

    Broader source: Energy.gov [DOE]

    International Association for Continuing Education and Training (IACET) continuing education units (CEUs) will be available for designated training sessions.

  3. SU-E-I-39: Molecular Image Guided Cancer Stem Cells Therapy

    SciTech Connect (OSTI)

    Abdollahi, H

    2014-06-01

    Purpose: Cancer stem cells resistance to radiation is a problematic issue that has caused a big fail in cancer treatment. Methods: As a primary work, molecular imaging can indicate the main mechanisms of radiation resistance of cancer stem cells. By developing and commissioning new probes and nanomolecules and biomarkers, radiation scientist will able to identify the essential pathways of radiation resistance of cancer stem cells. As the second solution, molecular imaging is a best way to find biological target volume and delineate cancer stem cell tissues. In the other hand, by molecular imaging techniques one can image the treatment response in tumor and also in normal tissue. In this issue, the response of cancer stem cells to radiation during therapy course can be imaged, also the main mechanisms of radiation resistance and finding the best radiation modifiers (sensitizers) can be achieved by molecular imaging modalities. In adaptive radiotherapy the molecular imaging plays a vital role to have higher tumor control probability by delivering high radiation doses to cancer stem cells in any time of treatment. The outcome of a feasible treatment is dependent to high cancer stem cells response to radiation and removing all of which, so a good imaging modality can show this issue and preventing of tumor recurrence and metastasis. Results: Our results are dependent to use of molecular imaging as a new modality in the clinic. We propose molecular imaging as a new radiobiological technique to solve radiation therapy problems due to cancer stem cells. Conclusion: Molecular imaging guided cancer stem cell diagnosis and therapy is a new approach in the field of cancer treatment. This new radiobiological imaging technique should be developed in all clinics as a feasible tool that is more biological than physical imaging.

  4. Celebrating Our #WomenInSTEM Video Series' First Birthday | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy #WomenInSTEM Video Series' First Birthday Celebrating Our #WomenInSTEM Video Series' First Birthday January 14, 2015 - 10:44am Addthis Image courtesy of Sarah Gerrity. Image courtesy of Sarah Gerrity. Matty Greene Matty Greene Former Videographer Allison Lantero Allison Lantero Digital Content Specialist, Office of Public Affairs MORE PROFILES Make sure to check out more #WomenInSTEM content by visiting Women @ Energy. It's imperative that we have all hands on deck to advance

  5. National Geographic Hosts the Energy Department's STEM Mentoring Café for

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Students | Department of Energy Geographic Hosts the Energy Department's STEM Mentoring Café for Students National Geographic Hosts the Energy Department's STEM Mentoring Café for Students February 24, 2016 - 4:20pm Addthis Hands on learning in science and technology gave 90 school kids and their teachers from Maryland, Virginia, and Washington, D.C. a first-hand look at STEM careers in February. Here, Carrie Seltzer, a research scientist and program manager at the National Geographic

  6. Find Your STEM Role Model: Join Our Google+ Hangout On March 5 | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Find Your STEM Role Model: Join Our Google+ Hangout On March 5 Find Your STEM Role Model: Join Our Google+ Hangout On March 5 February 28, 2014 - 12:07pm Addthis Find Your STEM Role Model: Join Our Google+ Hangout On March 5 There's an old axiom that you can't be what you can't see. Perhaps if you think about what inspired you to enter into your current job, or line of study, you'll recognize a role model or two that inspired you to take your current path. That's why NASA and the

  7. DOE video on PPPL's Angie Capece aims to encourage girls in STEM fields |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Princeton Plasma Physics Lab DOE video on PPPL's Angie Capece aims to encourage girls in STEM fields By Jeanne Jackson DeVoe July 25, 2014 Tweet Widget Google Plus One Share on Facebook PPPL physicist Angie Capece discusses the importance of science for the future of the U.S. and talks about what inspired her to become a scientist in a DOE video on women and STEM. (Photo by DOE videographer Matty Greene, "WomenInSTEM") PPPL physicist Angie Capece discusses the importance of science

  8. #WomenInSTEM: Making a Cleaner Future | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Making a Cleaner Future #WomenInSTEM: Making a Cleaner Future September 9, 2014 - 9:40am Addthis Watch our latest #WomenInSTEM profile of Mallory Lindgren to learn how her career in science and engineering is making a cleaner future for her son and how she is inspiring young girls to pursue STEM careers. | Video by Matty Greene. Rebecca Matulka Rebecca Matulka Former Digital Communications Specialist, Office of Public Affairs Matty Greene Matty Greene Former Videographer Meet Mallory Lindgren, a

  9. Science and Engineering Alliance, Inc. (SEA) Activities to Increase Participation of Students from Underrepresented Groups in Science, Technology, Engineering and Mathematics (STEM) Programs

    SciTech Connect (OSTI)

    Robert L. Shepard, PhD.

    2012-04-30

    To Increase Participation of Students from Underrepresented Groups in Science, Technology, Engineering and Mathematics (STEM) Programs.

  10. Educated and Equipped: Motivating Today's Youth to Become Tomorrow...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    STEM-literate workers are the engineers who design solar panels, wind turbines, and improved ... Find more STEM opportunities on ED's website. USA Science & Engineering Festival - Last ...

  11. Stored Guthrie cards as DNA [open quotes]Banks[close quotes

    SciTech Connect (OSTI)

    McEwen, J.E.; Reilly, P.R. )

    1994-07-01

    Recently there has been much discussion about the possibility of using dried blood spots on Guthrie cards as a source of DNA for research or testing purposes. The collections of Guthrie cards stored by state newborn-screening laboratories can thus be viewed as inchoate [open quotes]DNA banks[close quotes]. This has generated concern among some persons who are interested in preserving the privacy of medical records. This study examines the policies of state newborn-screening laboratories in the United States, regarding their retention of Guthrie cards and the degree to which they permit the sharing of those cards with various third parties. The authors found that although most laboratories retain their cards, if at all, for only a short time, a growing number plan to keep them for an extended period-and, in several cases, indefinitely. They also found that although most laboratories would decline to release individually identifiable blood spots from the cards to third parties without a written release or other explicit authorization, a large number would at least consider sharing anonymous cards for research purposes. 10 refs., 2 tabs.

  12. Longwall data bank. Semiannual project report, May 28-November 28, 1981

    SciTech Connect (OSTI)

    Not Available

    1981-12-01

    This is the first semiannual report on Contract No. DE-AC01-81FE00080 entitled Longwall Data Bank. The objectives of the program are to compile and transfer to the coal industry comprehensive longwall operational data representing 95 percent of the US longwall installations and to provide abstracts of domestic and foreign literature published since 1975 related to longwall production, productivity, and dust control. The number of longwall faces operating in the US is steadily increasing, but their full production potential has not been achieved due to problems such as respirable-dust control, excessive move time, roof control, etc. Generally, longwall operators are not knowledgeable of operational data for longwall operations other than their own, nor of results from current longwall research. Therefore, the purpose of this program is to establish more effective technology-transfer procedures. The literature search was completed, except for an ongoing review of weekly abstract publications. Working cards were completed for the comprehensive index file for all longwall publications of interest; abstracts were prepared for selected longwall publications. Revised questionnaire forms, with information from the original questionnaires, were forwarded for updating to nearly all companies presently in the questionnaire file. Selected operational data were tabulated and compared.

  13. Biological Macromolecular Structures Data from the RCSB Protein Data Bank (RCSB PDB)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The Research Collaboratory for Structural Bioinformatics (RCSB) is a non-profit consortium that works to improve understanding of the function of biological systems through the study of the 3-D structure of biological macromolecules. The RCSB PDB is one of three sites serving as deposition, data processing, and distribution sites of the Protein Data Bank Archive. Each site provides its own view of the primary data, thus providing a variety of tools and resources for the global community. RCSB is also the official keeper for the PDB archive, with sole access authority to the PDB archive directory structure and contents. The RCSB PDB Information Portal for Biological Macromolecular Structures offers online tools for search and retrieval, for visualizing structures, for depositing, validating, or downloading data, news and highlights, a discussion forum, and links to other areas of related research. The PDB archive is a repository of atomic coordinates and other information describing proteins and other important biological macromolecules. Structural biologists use methods such as X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy to determine the location of each atom relative to each other in the molecule. They then deposit this information, which is then annotated and publicly released into the archive by the wwPDB. Results can be viewed as 3-D images or models.

  14. ETO family protein Mtgr1 mediates Prdm14 functions in stem cell...

    Office of Scientific and Technical Information (OSTI)

    ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation Citation Details In-Document Search Title: ETO family protein Mtgr1 ...

  15. Buildings in a Test Tube: Validation of the Short-Term Energy Monitoring (STEM) Method (Preprint)

    SciTech Connect (OSTI)

    Judkoff, R.; Balcomb, J.D.; Barker, G.; Hancock, E.; Subbarao, K.

    2001-02-26

    This paper is extracted from a full-length technical report that presents a detailed analysis of the differences in thermal performance between the SIP and frame units and describes the validation of the STEM method.

  16. Veterans and STEM Mentoring Programs- Info Session and Brown Bag Networking

    Broader source: Energy.gov [DOE]

    January is National Mentoring Month. Join the Veterans Mentoring Program and the STEM Mentoring Program at DOE for information distribution and networking to meet current and potential mentors and...

  17. DOE video on PPPL's Angie Capece aims to encourage girls in STEM...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DOE video on PPPL's Angie Capece aims to encourage girls in STEM fields By Jeanne Jackson DeVoe July 25, 2014 Tweet Widget Google Plus One Share on Facebook PPPL physicist Angie...

  18. #WomenInSTEM: Inspiring Others to Become Scientists and Engineers |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Inspiring Others to Become Scientists and Engineers #WomenInSTEM: Inspiring Others to Become Scientists and Engineers January 27, 2015 - 11:56am Addthis Suzanne Singer is an energy and thermal fluids analyst at Lawrence Livermore National Laboratory (LLNL) and the latest profile in the Energy Department's #WomenInSTEM video series. | Video by Matty Greene. Matty Greene Matty Greene Former Videographer Meet Suzanne Singer, an energy and thermal fluids analyst at Lawrence

  19. Sandia National Laboratories: Sandia named a top employer for Native STEM

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    professionals Sandia named a top employer for Native STEM professionals By Valerie Larkin Thursday, April 28, 2016 Laurence Brown (163), Tribal Government Relations manager and co-chair of the AISES Corporate Advisory Council, says, "This is a great recognition of the tremendous talent pool of American Indian professionals at the Laboratories." Sandia has been named one of the Top 50 Workplaces for Native STEM Professionals by the American Indian Science and Engineering Society

  20. #WomenInSTEM: A Physicist Focuses on Scientific Advancement | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy A Physicist Focuses on Scientific Advancement #WomenInSTEM: A Physicist Focuses on Scientific Advancement July 17, 2014 - 4:59pm Addthis How Angela Capece got her start as a physicist at the Princeton Plasma Physics Laboratory. | Video by Matty Greene. Ben Dotson Ben Dotson Former Project Coordinator for Digital Reform, Office of Public Affairs Matty Greene Matty Greene Former Videographer More STEM Watch how scientists at the Princeton Plasma Physics Lab are creating a star on Earth.

  1. #WomenInSTEM: Stepping Stones From One Career to Another | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Stepping Stones From One Career to Another #WomenInSTEM: Stepping Stones From One Career to Another November 24, 2014 - 10:30am Addthis Watch our latest #WomenInSTEM profile of Cheryl Martin, Acting Director of the Advanced Research Projects Agency for Energy (ARPA-E). | Video by Matty Greene. Matty Greene Matty Greene Former Videographer Allison Lantero Allison Lantero Digital Content Specialist, Office of Public Affairs Meet Cheryl Martin, Acting Director of the Advanced Research

  2. ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance

    Office of Scientific and Technical Information (OSTI)

    and primordial germ cell formation (Journal Article) | SciTech Connect ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation Citation Details In-Document Search Title: ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation Authors: Nady, Nataliya ; Gupta, Ankit ; Ma, Ziyang ; Swigut, Tomek ; Koide, Akiko ; Koide, Shohei ; Wysocka, Joanna [1] ; UC) [2] + Show Author Affiliations

  3. Science Alliance Reveals STEM Pathways to the Future | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Science Alliance Reveals STEM Pathways to the Future Science Alliance Reveals STEM Pathways to the Future October 26, 2015 - 12:54pm Addthis Students try their hands at arranging items in glove boxes during the Sixth Annual Science Alliance at the DOE Portsmouth Site in Piketon, Ohio. The three-day event included several contests for hundreds of attendees while providing an immersive learning experience. Students try their hands at arranging items in glove boxes during the Sixth Annual Science

  4. NNSA & DOE Employees Use Tiny Smartphone Microscopes to Teach STEM |

    National Nuclear Security Administration (NNSA)

    National Nuclear Security Administration & DOE Employees Use Tiny Smartphone Microscopes to Teach STEM Wednesday, January 27, 2016 - 12:31pm NNSA Blog Users discovered items the device could magnify, such as yarn, human hair, and flower petals. Employees lunching on Friday, January 15, in the Department of Energy headquarters cafeteria received smartphone microscopes and a mission: Engage five students over Martin Luther King Jr. Day of Service in a STEM conversation using the device.

  5. Educating Scientifically - Advances in Physics Education Research

    ScienceCinema (OSTI)

    Finkelstein, Noah [University of Colorado, Colorado, USA

    2009-09-01

    It is now fairly well documented that traditionally taught, large-scale introductory physics courses fail to teach our students the basics. In fact, often these same courses have been found to teach students things we do not want. Building on a tradition of research in physics, the physics education research community has been researching the effects of educational practice and reforms at the undergraduate level for many decades. From these efforts and those within the fields of education, cognitive science, and psychology we have learned a great deal about student learning and environments that support learning for an increasingly diverse population of students in the physics classroom. This talk will introduce some of the ideas from physics education research, discuss a variety of effective classroom practices/ surrounding educational structures, and begin to examine why these do (and do not) work. I will present both a survey of physics education research and some of the exciting theoretical and experimental developments emerging from the University of Colorado.

  6. Education | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education Education Students from University of Texas-Pan American won 2nd place for their infographic and took home the People's Choice Award in the National Geothermal Student Competition in 2014. Students from University of Texas-Pan American won 2nd place for their infographic and took home the People's Choice Award in the National Geothermal Student Competition in 2014. The Geothermal Technologies Office supports an exciting array of educational initiatives for high school and college

  7. Education | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Jefferson Lab is committed to providing training and education to the next generation of scientists, mathematicians and engineers, and those who teach them. The lab provides a variety of programs and educational opportunities for students in grades K-12, as well as for undergraduates, graduate students and postdoctoral researchers. At Jefferson Lab, students and teachers gain access to leading scientists, world-class scientific facilities and instrumentation; and large-scale research

  8. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    October 15, 2007 [Education] Successful Partnering Produces Award Winning Proposal for Native Education Project Bookmark and Share In July 2007, the National Science Foundation (NSF) awarded funding to a proposal developed by ACRF Education and Outreach and WGBH Boston-public television's pre-eminent production house. The winning project, titled "Engaging Alaska Natives with the Geosciences," will add digital media and teacher professional development resources related to the Arctic

  9. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ARM Education Team Visits NSA Bookmark and Share Bernie Zak, NSA ARM site manager, gives a tour of the NSA site. In October, the ARM Education team met with several teachers and school administrators to reestablish a working relationship and to determine how to best enhance the existing ARM education outreach programs for the North Slope. Some of the current issues that the North Slope Borough School District is facing were discussed during these conversations. According to the No Child Left

  10. Ground water flow velocity in the bank of the Columbia River, Hanford, Washington

    SciTech Connect (OSTI)

    Ballard, S.

    1995-12-01

    To properly characterize the transport of contaminants from the sediments beneath the Hanford Site into the Columbia River, a suite of In Situ Permeable Flow Sensors was deployed to accurately characterize the hydrologic regime in the banks of the river. The three dimensional flow velocity was recorded on an hourly basis from mid May to mid July, 1994 and for one week in September. The first data collection interval coincided with the seasonal high water level in the river while the second interval reflected conditions during relatively low seasonal river stage. Two flow sensors located approximately 50 feet from the river recorded flow directions which correlated very well with river stage, both on seasonal and diurnal time scales. During time intervals characterized by falling river stage, the flow sensors recorded flow toward the river while flow away from the river was recorded during times of rising river stage. The flow sensor near the river in the Hanford Formation recorded a component of flow oriented vertically downward, probably reflecting the details of the hydrostratigraphy in close proximity to the probe. The flow sensor near the river in the Ringold Formation recorded an upward component of flow which dominated the horizontal components most of the time. The upward flow in the Ringold probably reflects regional groundwater flow into the river. The magnitudes of the flow velocities recorded by the flow sensors were lower than expected, probably as a result of drilling induced disturbance of the hydraulic properties of the sediments around the probes. The probes were installed with resonant sonic drilling which may have compacted the sediments immediately surrounding the probes, thereby reducing the hydraulic conductivity adjacent to the probes and diverting the groundwater flow away from the sensors.

  11. SIMULATION RESULTS OF RUNNING THE AGS MMPS, BY STORING ENERGY IN CAPACITOR BANKS.

    SciTech Connect (OSTI)

    MARNERIS, I.

    2006-09-01

    The Brookhaven AGS is a strong focusing accelerator which is used to accelerate protons and various heavy ion species to equivalent maximum proton energy of 29 GeV. The AGS Main Magnet Power Supply (MMPS) is a thyristor control supply rated at 5500 Amps, +/-go00 Volts. The peak magnet power is 49.5 Mwatts. The power supply is fed from a motor/generator manufactured by Siemens. The motor is rated at 9 MW, input voltage 3 phase 13.8 KV 60 Hz. The generator is rated at 50 MVA its output voltage is 3 phase 7500 Volts. Thus the peak power requirements come from the stored energy in the rotor of the motor/generator. The rotor changes speed by about +/-2.5% of its nominal speed of 1200 Revolutions per Minute. The reason the power supply is powered by the Generator is that the local power company (LIPA) can not sustain power swings of +/- 50 MW in 0.5 sec if the power supply were to be interfaced directly with the AC lines. The Motor Generator is about 45 years old and Siemens is not manufacturing similar machines in the future. As a result we are looking at different ways of storing energy and being able to utilize it for our application. This paper will present simulations of a power supply where energy is stored in capacitor banks. The simulation program used is called PSIM Version 6.1. The control system of the power supply will also be presented. The average power from LIPA into the power supply will be kept constant during the pulsing of the magnets at +/-50 MW. The reactive power will also be kept constant below 1.5 MVAR. Waveforms will be presented.

  12. Tenant Education and Training

    Broader source: Energy.gov [DOE]

    Better Buildings Neighborhood Program Multifamily / Low-Income Peer Exchange Call: Tenant Education and Training, Call Slides and Discussion Summary, July 28, 2011.

  13. Energy Education Data Jam

    Broader source: Energy.gov [DOE]

    This all-day data jam will bring together developers, educators, organizations, and energy experts to collaborate toward the goal of improving energy literacy in the United States.

  14. Education Office Housing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Office Housing Housing A housing forum and listings for housing in and around Los Alamos. Contact Postdoc Housing Email LANL Students' Association Email LANL postdoc...

  15. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dog (each representing an ARM site), but now provides easier navigation and great new learning activities. The Education website is now divided into three specialized and...

  16. Education Blog | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education Blog Education Blog The Office of Energy Efficiency and Renewable Energy's (EERE) education blog page highlights the initiatives, achievements and student competition results across all EERE technology offices including Solar, Wind & Water, Bioenergy, Vehicles, Geothermal, Hydrogen & Fuel Cells, Advanced Manufacturing, Homes, Buildings, and Government Energy Management. Blogs featured on this section of the education site announce educational opportunities including internships

  17. Long-term monitoring of reef corals at the Flower Garden Banks (northwest Gulf of Mexico): Reef coral population changes and historical incorporation of barium in Montastrea annularis

    SciTech Connect (OSTI)

    Deslarzes, K.J.P.

    1992-01-01

    Reef coral populations were monitored from 1988 to 1991 at the Flower Garden Banks located in the northwestern Gulf of Mexico. The status of reef coral populations, and natural or man-made factors potentially affecting their well-being were determined. Man-made chronic disturbances are degrading coral reef resources on a global scale. Yet, the Flower Garden coral reefs seem to have been sheltered from the effects of regional stresses generated by population growth and increased industrial activity. Since 1974, reef coral population levels have remained unchanged in the Montastrea-Diploria Zones at the Flower Garden Banks. Live coral cover ranges between 46 and 46.5%. Montastrea annularis and Diploria strigosa comprise 80% of the coral cover on either bank. The remainder of the cover is mostly shared by eight other taxa. Coral taxa appear to be more homogeneously distributed on the West Bank. The relatively greater number of Agaricia spp., Madracis decastis, and P. astreoides colonies on the East Bank may be the source of a decreased evenness. The health of reef corals was assessed using repetitive and non-repetitive photographic methods, and accretionary growth measurements of M. annularis. Reef corals have undergone small scale changes at the Flower Gardens probably reflecting natural disturbance, predation, disease, and inter-specific competition. White mat disease (ridge disease) is shown to generate more tissue loss than any of the three bleaching events that took place at the Flower Gardens (1989, 1990, and 1991). Advance to retreat linear ratios of encrusting growth revealed a net tissue gain on the East Bank and a net tissue loss on the West Bank. Growth rates of M. annularis were highly variable. The annual barium content from 1910 in 1989 in a M. annularis colony from the West Flower Garden did not reveal trends associated with the extensive oil and gas exploration in the northern Gulf of Mexico.

  18. Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells

    SciTech Connect (OSTI)

    Hamada, Shin [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan)] [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan); Masamune, Atsushi, E-mail: amasamune@med.tohoku.ac.jp [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan)] [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan); Takikawa, Tetsuya; Suzuki, Noriaki; Kikuta, Kazuhiro; Hirota, Morihisa [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan)] [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan); Hamada, Hirofumi [Laboratory of Oncology, Department of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji (Japan)] [Laboratory of Oncology, Department of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji (Japan); Kobune, Masayoshi [Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo (Japan)] [Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo (Japan); Satoh, Kennichi [Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori (Japan)] [Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, Natori (Japan); Shimosegawa, Tooru [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan)] [Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai (Japan)

    2012-05-04

    Highlights: Black-Right-Pointing-Pointer Pancreatic stellate cells (PSCs) promote the progression of pancreatic cancer. Black-Right-Pointing-Pointer Pancreatic cancer cells co-cultured with PSCs showed enhanced spheroid formation. Black-Right-Pointing-Pointer Expression of stem cell-related genes ABCG2, Nestin and LIN28 was increased. Black-Right-Pointing-Pointer Co-injection of PSCs enhanced tumorigenicity of pancreatic cancer cells in vivo. Black-Right-Pointing-Pointer This study suggested a novel role of PSCs as a part of the cancer stem cell niche. -- Abstract: The interaction between pancreatic cancer cells and pancreatic stellate cells (PSCs), a major profibrogenic cell type in the pancreas, is receiving increasing attention. There is accumulating evidence that PSCs promote the progression of pancreatic cancer by increasing cancer cell proliferation and invasion as well as by protecting them from radiation- and gemcitabine-induced apoptosis. Recent studies have identified that a portion of cancer cells, called 'cancer stem cells', within the entire cancer tissue harbor highly tumorigenic and chemo-resistant phenotypes, which lead to the recurrence after surgery or re-growth of the tumor. The mechanisms that maintain the 'stemness' of these cells remain largely unknown. We hypothesized that PSCs might enhance the cancer stem cell-like phenotypes in pancreatic cancer cells. Indirect co-culture of pancreatic cancer cells with PSCs enhanced the spheroid-forming ability of cancer cells and induced the expression of cancer stem cell-related genes ABCG2, Nestin and LIN28. In addition, co-injection of PSCs enhanced tumorigenicity of pancreatic cancer cells in vivo. These results suggested a novel role of PSCs as a part of the cancer stem cell niche.

  19. Vehicle Technologies Program Educational Activities

    SciTech Connect (OSTI)

    2011-12-13

    Description of educational activities including: EcoCAR2: Plugging In to the Future, EcoCAR: The NeXt Challenge, Green Racing, Automotive X Prize, Graduate Technology Automotive Education (GATE), and Hydrogen Education.

  20. ORISE: Center for Science Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Education as a national resource for featuring proven approaches and programs that can help make science, technology, engineering and mathematics education more effective. ...

  1. Education Homepage | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Services Education Homepage Education Homepage NEW ... The Office of Energy Efficiency and Renewable Energy's ... Illustration of an apple. Teach Find lesson plans, science ...

  2. Science Education | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Science & Innovation Science Education Science Education May 4, 2016 Debra Rowe, Oakland Community College, California Meet the Women Leading the Clean Energy Revolution These ...

  3. Environmental Assessment and Finding of No Significant Impact: Implementation of the Wetland Mitigation Bank Program at the Savannah River Site

    SciTech Connect (OSTI)

    N /A

    1999-04-28

    The Department of Energy (DOE) has prepared an environmental assessment (EA) (DOE/EA-1205) for the proposed implementation of a wetland mitigation bank program at the Savannah River Site (SRS), located near Aiken, South Carolina. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, the preparation of an environmental impact statement (EIS) is not required, and DOE is issuing this Finding of No Significant Impact (FONSI) and Floodplain Statement of Findings.

  4. Longwall data bank. Quarterly project status report, February 28-May 28, 1982 and semiannual report No. 2

    SciTech Connect (OSTI)

    Not Available

    1982-07-01

    During the period of February through May 1982, five updated longwall questionnaires were received from operators and two additional longwalls were added to the questionnaire file. Two requests for information from the Data Bank were received and processed. Data from questionnaires were tabulated and analyzed. Also, relevant coal-mining publications were reviewed for longwall references and 29 were added to the index file. Thirty abstracts were prepared from selected R and D reports, conference papers, and articles in professional journals. These and 15 others prepared since the first semiannual report appear in Appendix B.

  5. #WomenInSTEM: Stepping Stones From One Career to Another

    ScienceCinema (OSTI)

    Martin, Cheryl

    2014-11-24

    Meet Cheryl Martin, Acting Director of the Advanced Research Projects Agency for Energy (ARPA-E) and the latest profile in the Energy Department's #WomenInSTEM video series. Cheryl looks at transformational projects to explore the uncharted territories of energy technology to generate options for entirely new paths to create, store and use energy. There are many challenges to overcome in the energy field, and it's important to have a diverse set of voices in STEM careers to meet these demands. Cheryl recommends that young women include all the skills they have - those gained at formal jobs as well as through volunteering or nonprofit organizations - when they take their next career step. These skills form the stepping stones that lead from one career to the next. And with a solid grounding in STEM, the opportunities are endless.

  6. A possible usage of a CDK4 inhibitor for breast cancer stem cell-targeted therapy

    SciTech Connect (OSTI)

    Han, Yu Kyeong; Lee, Jae Ho; Park, Ga-Young; Chun, Sung Hak; Han, Jeong Yun; Kim, Sung Dae; Lee, Janet; Center for Molecular Medicine, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Gyeonggi 440-746 ; Lee, Chang-Woo; Center for Molecular Medicine, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Gyeonggi 440-746; Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Suwon, Gyeonggi 440-746 ; Yang, Kwangmo; Department of Radiation Oncology, Dongnam Institute of Radiological and Medical Sciences, Busan 619-953; Department of Radiation Oncology, Korea Institute of Radiological and Medical Sciences, Seoul 139-709 ; Lee, Chang Geun

    2013-01-25

    Highlights: ? A CDK4 inhibitor may be used for breast cancer stem cell-targeted therapy. ? The CDK4 inhibitor differentiated the cancer stem cell population (CD24{sup ?}/CD44{sup +}) of MDA-MB-231. ? The differentiation of the cancer stem cells by the CDK4 inhibitor radiosensitized MDA-MB-231. -- Abstract: Cancer stem cells (CSCs) are one of the main reasons behind cancer recurrence due to their resistance to conventional anti-cancer therapies. Thus, many efforts are being devoted to developing CSC-targeted therapies to overcome the resistance of CSCs to conventional anti-cancer therapies and decrease cancer recurrence. Differentiation therapy is one potential approach to achieve CSC-targeted therapies. This method involves inducing immature cancer cells with stem cell characteristics into more mature or differentiated cancer cells. In this study, we found that a CDK4 inhibitor sensitized MDA-MB-231 cells but not MCF7 cells to irradiation. This difference appeared to be associated with the relative percentage of CSC-population between the two breast cancer cells. The CDK4 inhibitor induced differentiation and reduced the cancer stem cell activity of MDA-MB-231 cells, which are shown by multiple marker or phenotypes of CSCs. Thus, these results suggest that radiosensitization effects may be caused by reducing the CSC-population of MDA-MB-231 through the use of the CDK4 inhibitor. Thus, further investigations into the possible application of the CDK4 inhibitor for CSC-targeted therapy should be performed to enhance the efficacy of radiotherapy for breast cancer.

  7. Monitoring bank erosion at the Locke Island Archaeological National Register District: Summary of 1996/1997 field activities

    SciTech Connect (OSTI)

    Nickens, P.R.; Bjornstad, B.N.; Nickens, P.R.; Cadoret, N.A.; Wright, M.K.

    1998-08-01

    Locke Island is located in the Columbia River in south-central Washington. The US Department of Energy (DOE) owns Locke Island as part of its Hanford Site. In the 1960s and 1970s, as a result of intensive irrigation developments on the inland shoreline to the east of the island, the White Bluffs, which form the eastern boundary of the Columbia River channel in this area, began to show geological failures as excess irrigation water seeped out along the bluffs. One of the largest such failures, known as the Locke Island Landslide, is located just east of Locke Island. By the early 1980s, this landslide mass had moved westward into the river channel toward the island and was diverting the current at the island`s eastern perimeter. Erosion of the bank in the center of the island accelerated, threatening the cultural resources. By the early 1990s, the erosion had exposed cultural features and artifacts along the bank, leading to the beginning of intermittent monitoring of the cutbank. In 1994, DOE initiated more scheduled, systematic monitoring of island erosion to better understand the physical processes involved as well as mitigate ongoing loss of the archaeological record.

  8. NREL: Workforce Development and Education Programs - National...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and math topics. It is well recognized that the middle school years are the most productive time to attract students to science, technology, engineering, and math (STEM) ...

  9. Summer Educational Internship Deadlines | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    program encourages undergraduate students to pursue science, technology, engineering, and mathematics (STEM) careers by providing research internships at one of 15 participating...

  10. LATINO Magazine Nuestro Futuro Latino Education Conference

    Broader source: Energy.gov [DOE]

    "Conference participants will join in discussions with experts drawn from academia, business, government, and Hispanic organizations such as SHPE and Great minds in STEM. Invited panelists and...

  11. The 2015 Conference for Young Women in STEM is a smashing success! |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Princeton Plasma Physics Lab The 2015 Conference for Young Women in STEM is a smashing success! April 2, 2015 A beautiful Thursday morning at the usually quiet and peaceful Frick Chemistry building at Princeton University, turned into a bustling hub of science and technology for a day on March 19, 2015. Over 450 young women, in grades 7-10, and their chaperones came from all over NJ, PA and even MD, to attend PPPL's 14th Annual young Women's Conference in STEM. With over 25 exhibits, the

  12. No cookies but lots of science at Girl Scout STEM Fair at PPPL | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab No cookies but lots of science at Girl Scout STEM Fair at PPPL By Jeanne Jackson DeVoe May 27, 2014 Tweet Widget Google Plus One Share on Facebook Atiba Brereton, a diagnostic engineer, looks on as Mackenzie Keane, left, a fourth grader from East Brunswick, N.J, and Shreya Joshi, a fifth grader from West Windsor, N.J., try their hands at a cryogenics experiment at the Girl Scout STEM Fair at PPPL on May 17. (Photo by Elle Starkman/PPPL Office of Communications) Atiba

  13. Registration for the 2015 Conference for Young Women in STEM is OPEN! |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Princeton Plasma Physics Lab Registration for the 2015 Conference for Young Women in STEM is OPEN! October 15, 2014 The 2015 Young Women's Conference in STEM will be held on Thursday, March 19, 2015 at Princeton University's Frick Chemistry building and registration is now OPEN! Please visit our Young Women's Conference program page to find out more about this great event and to register your group here! Remember, young women must be in grades 7-10 there is a 10 student and 1 chaperone limit

  14. #WomenInSTEM: Using Science & Math to Power the Globe

    ScienceCinema (OSTI)

    Jordan, Rhonda

    2014-06-04

    Growing up, Dr. Rhonda Jordan always enjoyed math and science. After completing her master's in electrical engineering at Columbia University she co-founded a startup in Tanzania that provides access to power for residents who are not connected to the electrical grid. This video is part of the Energy Department's #WomenInSTEM video series. At the Energy Department, we're committed to supporting a diverse talent pool of STEM innovators ready to address the challenges and opportunities of our growing clean energy economy.

  15. #WomenInSTEM: Using Science & Math to Power the Globe

    SciTech Connect (OSTI)

    Jordan, Rhonda

    2014-05-27

    Growing up, Dr. Rhonda Jordan always enjoyed math and science. After completing her master's in electrical engineering at Columbia University she co-founded a startup in Tanzania that provides access to power for residents who are not connected to the electrical grid. This video is part of the Energy Department's #WomenInSTEM video series. At the Energy Department, we're committed to supporting a diverse talent pool of STEM innovators ready to address the challenges and opportunities of our growing clean energy economy.

  16. Analysis, Data Systems, and Education

    Broader source: Energy.gov [DOE]

    Below are the project presentations and respective peer review results for Analysis, Data Systems, and Education.

  17. ORISE: Science Education Programs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Education Programs The U.S. Department of Energy (DOE) and more than a dozen other federal agencies rely on the Oak Ridge Institute for Science and Education (ORISE) to help meet future needs in critical science and technology areas through the recruitment and training of our nation's next generation of scientists and engineers. To meet these pressing demands, ORISE assesses current science and technology labor needs and then designs and implements programs that meet the unique goals of

  18. Education | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Education The MFRC has established a network of Midwest crime laboratories and university-based forensic science programs. This network has two general goals: help universities become better casework, research, and development partners for crime laboratories; and to engage crime laboratories in university efforts. These efforts can better-prepare the next generation of forensic scientists, advance the state-of-the-art in forensic science research, and influence students whose

  19. ORISE: Science Education Publications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Education Publications ORISE reports track U.S. scientific workforce trends The Oak Ridge Institute for Science and Education (ORISE) has published several reports that analyze labor trends, assess classroom technologies and examine other characteristics essential for enhancing America's global competitiveness. The following publications are available as PDF files. To view them, you will need the free Adobe Reader plug-in. Nuclear Engineering Nuclear Engineering Enrollments and Degrees

  20. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    April 9, 2007 [Education] Barrow Teachers Learn About International Polar Year Bookmark and Share Two Barrow teachers, Gary Boen and Imelda Cabana, were sent to the NSTA conference in St. Louis. Science teachers in Barrow, Alaska, know that climate change is something their students can experience simply by stepping out into their own back yards. But that doesn't mean teachers don't need resources and materials to help them engage their students in climate studies. Last month, ACRF Education and

  1. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    November 2002 ARM Climate Change Workshops Bookmark and Share Teacher measuring temperature as a part of the "Arctic Microclimates" Lesson. Carrie Talus telling the participating teachers about the ARM Project and the ARM Education Program. Laura Marsh and Carrie Talus of ARM Education recently presented teachers' workshops in basic climate change science at three schools in the North Slope. Marsh's presentations included a discussion of global climate change such as El Niño, sea

  2. Five Native Colleges Receive Grants to Advance Tribal Careers in STEM

    Broader source: Energy.gov [DOE]

    On Oct. 29 during his keynote speech at the Society for Advancement of Chicanos/Hispanics & Native Americans in Science (SACNAS) 2015 Diversity in STEM Conference, U.S. Department of Energy (DOE) Secretary Ernest Moniz announced a new program to help ‎tribal‬ colleges prepare students for careers in science, technology, engineering, and mathematics, and specifically in advanced manufacturing.

  3. Identification of stem cells from human umbilical cord blood with embryonic and hematopoietic characteristics

    SciTech Connect (OSTI)

    Zhao Yong . E-mail: yongzhao@uic.edu; Wang Honglan; Mazzone, Theodore

    2006-08-01

    We identified stem cells from the umbilical cord blood, designated cord blood-stem cells (CB-SC). CB-SC displayed important embryonic stem (ES) cell characteristics including expression of ES-cell-specific molecular markers including transcription factors OCT-4 and Nanog, along with stage-specific embryonic antigen (SSEA)-3 and SSEA-4. CB-SC also expressed hematopoietic cell antigens including CD9, CD45 and CD117, but were negative for CD34. CB-SC displayed very low immunogenicity as indicated by expression of a very low level of major histocompatibility complex (MHC) antigens and failure to stimulate the proliferation of allogeneic lymphocytes. CB-SC could give rise to cells with endothelial-like and neuronal-like characteristics in vitro, as demonstrated by expression of lineage-associated markers. Notably, CB-SC could be stimulated to differentiate into functional insulin-producing cells in vivo and eliminated hyperglycemia after transplantation into a streptozotocin-induced diabetic mouse model. These findings may have significant potential to advance stem-cell-based therapeutics.

  4. SPECT Imaging for in vivo tracking of NIS containing stem cells

    SciTech Connect (OSTI)

    Lee, Zhenghong

    2013-04-02

    The proposed study contains two groups of imaging experiments: 1) human mesenchymal stem cells supporting in vivo survival of unrelated donor hematopoietic stem cells; 2) gene transduction and selection of mutant MGMT genes on human hematopoietic stem cells conferring resistance to BC+BCNU. There is increasing evidence that adult human tissues harbor stem and progenitor cells that can be used for therapeutic purposes. We had focused on the Mesenchymal Stem Cells (MSCs) found in human bone marrow and investigated these cells in the context of autologous and allogeneic hematopoietic stem cell transplantation to a) facilitate rapid hematopoietic engraftment in cancer patients receiving high dose chemotherapy and b) to modulate the graft-versus-host disease (GVHD). We have demonstrated that culture-expanded autologous and allogeneic MSCs can be safely infused into humans and the preliminary results showed that MSCs facilitate hematopoietic engraftment and reduce GVHD. On the other hand, studies of gene transfer with drug resistant selection suggest major perturbations to the process of hematopoietic reconstitution and the confounding issue of organ toxicity and recovery that takes place in the host. We have found that limiting numbers of hematopoietic stem cells transduced with MGMT repopulate the bone marrow of primary and secondary recipient mice. We are also particularly interested in the dynamics of engraftment and selection in regions of bones, liver, spleen and lung, where we have previously seen marked evidence of engraftment. All the measurements have required animal sacrifice and single point determinations of engraftment in individual and cohorts of mice. Heretofore it has not been possible to study the dynamics of engraftment and enrichment. In the upcoming application, we propose to develop an imaging method to track intravenously infused stem cells in vivo at preset time points to understand their homing and proliferation. Specifically, we propose to use Na+/I- symporter (NIS) gene as a reporter gene (imagene) for non-invasive imaging of infused stem cellsâ?? distribution and persistence in vivo on small animal models. NIS is an intrinsic membrane glycoprotein that mediates active iodide (I-) uptake into normal thyroid follicular cells and other cells. The advantages of using NIS for non-invasive and repeated scintigraphic imaging in this application are: a) NIS is not a foreign gene and thus eliminate the immunoresponse problem; b) radiotracer or substrate for NIS is simply radioiodide (I-125, I- 123, I-124, and I-124) or [Tc-99m]-pertechnetate, no radiosynthesis is needed. It has been shown that NIS gene transfer can induce radioactive iodide uptake in a variety of cells and that xenografts expressing exogenous NIS could be imaged by non-invasive scintigraphic imaging. The specific aims are: 1.Determine the feasibility, stability and physiological effects of human NIS gene expression on human HSCs and MSCs in vitro. 2.Determine the engraftment of human HSC and MSC co-infused in NOD-SCID mice. 3.Transduce both a drug resistance gene and an imagene into bone marrow stem cells, and follow the dynamics of engraftment after selection in real time.

  5. EERE: Education Calendar | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    November 2015 < prev next > Sun Mon Tue Wed Thu Fri Sat 1 2 3 4 5 6 7 8 9 10 11 12 13 14 STEM Volunteer Training: Crafting Your STEM Story 3:00PM to 4:00PM EST 15 16 17 18 19 20 21...

  6. Articles about Education Outreach | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education Outreach Articles about Education Outreach RSS Below are stories about education and outreach featured by the U.S. Department of Energy (DOE) Wind Program. October 1,...

  7. Longwall data bank. Quarterly project status report, August 28-November 28, 1982 and semiannual report No. 3

    SciTech Connect (OSTI)

    Not Available

    1983-01-01

    The objectives of the program are to compile and transfer to the coal industry comprehensive operational data on US longwall installations, and to provide abstracts of domestic and foreign literature related to longwall production, productivity, and dust control published since 1975. During the period of August through November 1982, five updated longwall questionnaires were received from operators and two additional longwalls were added to the questionnaire file. Three requests for information from the Data Bank were received and processed. Data from questionnaires were tabulated and analyzed. Also, relevant coal-mining publications were reviewed for articles on longwall mining. Fifteen abstracts were prepared from selected R and D reports, conference papers, and articles in professional journals. These abstracts are included in Appendix B.

  8. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    8, 2006 [Education] Educational Kiosk Installed at ARM Site in Nauru Bookmark and Share The kiosk at Nauru. Children surround the newly installed kiosk at the Nauru airport. Surround by the Pacific Ocean, the Republic of Nauru is a small island inhabited by people who have a keen understanding of the importance of weather and climate. Coastal erosion, drought and rising sea level are only a few concerns Nauruans have related to climate change, and now they have a new forum for expressing those

  9. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Judges Science Fairs Bookmark and Share This spring, ARM Education and Outreach helped the local community of Northern New Mexico by judging science fairs with other educators and scientists. Margo Bachman went to the Santo Domingo School of the Santo Domingo Pueblo, New Mexico to assist judging projects from 5, 6, 7 and 8 graders. Tina Summer and Janet Lynch went to the McCurdy School in Espanola, New Mexico for a high school science fair. They all spotted some excellent projects in

  10. H2 Educate Teacher Guide

    Broader source: Energy.gov [DOE]

    This H2 Educate Teacher Guide provides information about hydrogen energy and was developed by the National Energy Education Development (NEED) Project for the U.S. Department of Energy's Hydrogen Program.

  11. PBS: Wind Power for Educators

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PBS: Wind Power for Educators Grades: 5-8, 9-12 Topic: Wind Energy Owner: PBS This educational material is brought to you by the U.S. Department of Energy's Office of Energy ...

  12. H2 Educate! Teacher Guide

    Fuel Cell Technologies Publication and Product Library (EERE)

    H2 Educate! Teacher and Student Guides - These new guides were developed by the National Energy Education Development (NEED) Project's Teacher Advisory Board for the DOE Hydrogen Program. Sentech, Inc

  13. H2 Educate! Student Guide

    Fuel Cell Technologies Publication and Product Library (EERE)

    H2 Educate! Teacher and Student Guides - These new guides were developed by the National Energy Education Development (NEED) Project's Teacher Advisory Board for the DOE Hydrogen Program. Sentech, Inc

  14. Hydrogen Technology Education Workshop Proceedings

    Fuel Cell Technologies Publication and Product Library (EERE)

    This document outlines activities for educating key target audiences, as suggested by workshop participants. Held December 4-5, 2002, the Hydrogen Technology Education Workshop kicked off a new educat

  15. H2 Educate Student Guide

    Broader source: Energy.gov [DOE]

    This H2 Educate Student Guide provides information about hydrogen energy and was developed by the National Energy Education Development (NEED) Project for the U.S. Department of Energy's Hydrogen Program.

  16. Education Homepage | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Services » Education Homepage Education Homepage NEW! Energy Literacy Video Series NEW! Energy Literacy Video Series Read more Find Resources for Planning Your Clean Energy Career Find Resources for Planning Your Clean Energy Career Read more Use Energy Literacy Materials to Promote Energy Education Use Energy Literacy Materials to Promote Energy Education Read more BioenergizeME Infographic Challenge: Cellulosic Ethanol BioenergizeME Infographic Challenge: Cellulosic Ethanol Read more Energy

  17. Science Education | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education Science Education Energy is a physical quantity that follows precise natural laws. Check out our NEW Energy Literacy Video Series, which highlights the 7 Essential Principles of Energy to help engage students in energy. | Energy Department Video. For kids of all ages, there is always something new to learn about science and technology. The Energy Department supports science education through educational online content, resources for parents and teachers, internships and student

  18. Education | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Science Education Welcome to the Science Education Department at the Princeton Plasma Physics Laboratory (PPPL), where we combine the lab's core research activities with science education programs to create a center of excellence for students, teachers and the general public. We contribute to the training of the next generation of scientists and engineers, collaborate with K-12 teachers on ways to improve science teaching using an inquiry-based approach to learning, and improve the

  19. Women's Education, Women's Empowerment - Celebrating National...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Women's Education, Women's Empowerment - Celebrating National Women's History Month this March Women's Education, Women's Empowerment - Celebrating National Women's History Month ...

  20. Minority Education and Community Development | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Development Minority Education and Community Development Minority serving institutions ... Minority Serving Institutions are institutions of higher education that serve minority ...

  1. Vegetable Oil from Leaves and Stems: Vegetative Production of Oil in a C4 Crop

    SciTech Connect (OSTI)

    2012-01-01

    PETRO Project: Arcadia Biosciences, in collaboration with the University of California-Davis, is developing plants that produce vegetable oil in their leaves and stems. Ordinarily, these oils are produced in seeds, but Arcadia Biosciences is turning parts of the plant that are not usually harvested into a source of concentrated energy. Vegetable oil is a concentrated source of energy that plants naturally produce and is easily separated after harvest. Arcadia Biosciences will isolate traits that control oil production in seeds and transfer them into leaves and stems so that all parts of the plants are oil-rich at harvest time. After demonstrating these traits in a fast-growing model plant, Arcadia Biosciences will incorporate them into a variety of dedicated biofuel crops that can be grown on land not typically suited for food production

  2. Side-by-Side Thermal Tests of Modular Offices: A Validation Study of the STEM Method

    SciTech Connect (OSTI)

    Judkoff, R.; Balcomb, J.D.; Hancock, C.E.; Barker, G.; Subbarao, K.

    2001-01-11

    Two modular office units were tested at the National Renewable Energy Laboratory (NREL) to establish each unit's thermal performance. The two units were nearly identical in appearance, but one was built with structural insulating panels (SIP), and the other was built using standard frame construction. The primary objective of these tests was to compare the thermal performance of buildings using SIP and standard frame construction. Both units were tested under carefully controlled steady-state conditions in the NREL large-scale environmental enclosure. They were then moved outdoors where Short-Term Energy Monitoring (STEM) tests were performed, and long-term heating and cooling energy use was measured. A secondary objective was to evaluate the accuracy of the NREL STEM method by comparing the results of outdoor STEM tests to steady-state indoor test results. STEM is a method developed by NREL to determine key thermal parameters of a building in-situ, based on a 3-day test sequence. The indoor test facility also provided the opportunity to investigate the phenomenon of infiltration heat recovery in a real building, under carefully controlled conditions, to evaluate the stability of the concentration decay method of tracer gas-based infiltration monitoring, and to compare the blower-door method with the tracer-gas technique in determining infiltration.This project was a cooperative effort with the Structural Insulated Panel Association, the Modular Building Institute, All-American Modular (AAM, the manufacturer of the units), and GE Capitol (the owner of the units). Richard Harmon, the president of AAM, requested NREL's assistance in exploring the feasibility of converting his manufacturing process to SIP construction. His engineering staff needed to assess which comfort and energy benefits might be associated with this new technology. AAM manufactured the two units, and NREL tested the modules for 8 months.

  3. CNS Donates to Girls Inc. to Expand its STEM Programs for Girls | Y-12

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    National Security Complex Donates to Girls Inc. ... CNS Donates to Girls Inc. to Expand its STEM Programs for Girls Posted: April 4, 2016 - 10:55am Girls Inc. Executive Director Rhoni Basden (left) accepts a donation from Consolidated Nuclear Security, LLC (CNS) Vice President for Operations Support Darrell Graddy (center) with CNS employee and Girls Inc. board member, Sheryl Houston (right). To get more girls interested and excited about science, math and technology, Consolidated Nuclear

  4. Who's on FIRST? Inspiring STEM through robotics | Y-12 National Security

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Complex Who's on FIRST? Inspiring ... Who's on FIRST? Inspiring STEM through robotics Posted: February 25, 2016 - 3:57pm Students from Farragut High School work on their entry for the FIRST (For Inspiration & Recognition of Science & Technology) robotics competition. Consolidated Nuclear Security, LLC plays an active role in strengthening the quality of FIRST (For Inspiration & Recognition of Science & Technology) robotics competitions for individual high school-aged teams in

  5. Thalidomide induced early gene expression perturbations indicative of human embryopathy in mouse embryonic stem cells

    SciTech Connect (OSTI)

    Gao, Xiugong Sprando, Robert L.; Yourick, Jeffrey J.

    2015-08-15

    Developmental toxicity testing has traditionally relied on animal models which are costly, time consuming, and require the sacrifice of large numbers of animals. In addition, there are significant disparities between human beings and animals in their responses to chemicals. Thalidomide is a species-specific developmental toxicant that causes severe limb malformations in humans but not in mice. Here, we used microarrays to study transcriptomic changes induced by thalidomide in an in vitro model based on differentiation of mouse embryonic stem cells (mESCs). C57BL/6 mESCs were allowed to differentiate spontaneously and RNA was collected at 24, 48, and 72 h after exposure to 0.25 mM thalidomide. Global gene expression analysis using microarrays revealed hundreds of differentially expressed genes upon thalidomide exposure that were enriched in gene ontology (GO) terms and canonical pathways associated with embryonic development and differentiation. In addition, many genes were found to be involved in small GTPases-mediated signal transduction, heart development, and inflammatory responses, which coincide with clinical evidences and may represent critical embryotoxicities of thalidomide. These results demonstrate that transcriptomics in combination with mouse embryonic stem cell differentiation is a promising alternative model for developmental toxicity assessment. - Highlights: • Studied genomic changes in mouse embryonic stem cells upon thalidomide exposure • Identified gene expression changes that may represent thalidomide embryotoxicity • The toxicogenomic changes coincide well with known thalidomide clinical outcomes. • The mouse embryonic stem cell model is suitable for developmental toxicity testing. • The model has the potential for high-throughput screening of a multitude of compounds.

  6. Students and Parents at Carver Middle School Explore STEM with Jefferson

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lab (Newport News Public Schools TV Media Center,This Just In program) | Jefferson Lab Students and Parents at Carver Middle School Explore STEM with Jefferson Lab (Newport News Public Schools TV Media Center,This Just In program) External Link: http://nnpstv.com/mediacenter/video/1326/This-Just-In-110-Week-of-April-2-2012 By jlab_admin on Mon, 2012-04-02

  7. Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits

    SciTech Connect (OSTI)

    Ma, Li; Mao, Rurong; Shen, Ke; Zheng, Yuanhong; Li, Yueqi; Liu, Jianwen; Ni, Lei

    2014-07-18

    Highlights: This paper supports the anti-tumor effects of AT-I on gastric cancer in vitro. AT-I attenuates gastric cancer stem cell traits. It is the systematic study regarding AT-I suppression of Notch pathway in GC and GCSLCs. - Abstract: Atractylenolide I (AT-I), one of the main naturally occurring compounds of Rhizoma Atractylodis Macrocephalae, has remarkable anti-cancer effects on various cancers. However, its effects on the treatment of gastric cancer remain unclear. Via multiple cellular and molecular approaches, we demonstrated that AT-I could potently inhibit cancer cell proliferation and induce apoptosis through inactivating Notch pathway. AT-I treatment led to the reduction of expressions of Notch1, Jagged1, and its downstream Hes1/ Hey1. Our results showed that AT-I inhibited the self-renewal capacity of gastric stem-like cells (GCSLCs) by suppression of their sphere formation capacity and cell viability. AT-I attenuated gastric cancer stem cell (GCSC) traits partly through inactivating Notch1, leading to reducing the expressions of its downstream target Hes1, Hey1 and CD44 in vitro. Collectively, our results suggest that AT-I might develop as a potential therapeutic drug for the treatment of gastric cancer.

  8. Enhancement of neurite outgrowth in neuron cancer stem cells by growth on 3-D collagen scaffolds

    SciTech Connect (OSTI)

    Chen, Chih-Hao; Neurosurgery, Department of Surgery, Kaohsiung Veterans General Hospital, Taiwan, ROC; Department of Biomedical Engineering, I-Shou University, Taiwan, ROC ; Kuo, Shyh Ming; Liu, Guei-Sheung; Chen, Wan-Nan U.; Chuang, Chin-Wen; Liu, Li-Feng

    2012-11-09

    Highlights: Black-Right-Pointing-Pointer Neuron cancer stem cells (NCSCs) behave high multiply of growth on collagen scaffold. Black-Right-Pointing-Pointer Enhancement of NCSCs neurite outgrowth on porous collagen scaffold. Black-Right-Pointing-Pointer 3-D collagen culture of NCSCs shows an advance differentiation than 2-D culture. -- Abstract: Collagen is one component of the extracellular matrix that has been widely used for constructive remodeling to facilitate cell growth and differentiation. The 3-D distribution and growth of cells within the porous scaffold suggest a clinical significance for nerve tissue engineering. In the current study, we investigated proliferation and differentiation of neuron cancer stem cells (NCSCs) on a 3-D porous collagen scaffold that mimics the natural extracellular matrix. We first generated green fluorescence protein (GFP) expressing NCSCs using a lentiviral system to instantly monitor the transitions of morphological changes during growth on the 3-D scaffold. We found that proliferation of GFP-NCSCs increased, and a single cell mass rapidly grew with unrestricted expansion between days 3 and 9 in culture. Moreover, immunostaining with neuronal nuclei (NeuN) revealed that NCSCs grown on the 3-D collagen scaffold significantly enhanced neurite outgrowth. Our findings confirmed that the 80 {mu}m porous collagen scaffold could enhance attachment, viability and differentiation of the cancer neural stem cells. This result could provide a new application for nerve tissue engineering and nerve regeneration.

  9. Nukbone promotes proliferation and osteoblastic differentiation of mesenchymal stem cells from human amniotic membrane

    SciTech Connect (OSTI)

    Rodrguez-Fuentes, Nayeli; Rodrguez-Hernndez, Ana G.; Enrquez-Jimnez, Juana; Alcntara-Quintana, Luz E.; Fuentes-Mera, Lizeth; Pia-Barba, Mara C.; Zepeda-Rodrguez, Armando; and others

    2013-05-10

    Highlights: Nukbone showed to be a good scaffold for adhesion, proliferation and differentiation of stem cells. Nukbone induced osteoblastic differentiation of human mesenchymal stem cells. Results showed that Nukbone offer an excellent option for bone tissue regeneration due to properties. -- Abstract: Bovine bone matrix Nukbone (NKB) is an osseous tissue-engineering biomaterial that retains its mineral and organic phases and its natural bone topography and has been used as a xenoimplant for bone regeneration in clinics. There are not studies regarding its influence of the NKB in the behavior of cells during the repairing processes. The aim of this research is to demonstrate that NKB has an osteoinductive effect in human mesenchymal stem cells from amniotic membrane (AM-hMSCs). Results indicated that NKB favors the AM-hMSCs adhesion and proliferation up to 7 days in culture as shown by the scanning electron microscopy and proliferation measures using an alamarBlue assay. Furthermore, as demonstrated by reverse transcriptase polymerase chain reaction, it was detected that two gene expression markers of osteoblastic differentiation: the core binding factor and osteocalcin were higher for AM-hMSCs co-cultured with NKB in comparison with cultivated cells in absence of the biomaterial. As the results indicate, NKB possess the capability for inducing successfully the osteoblastic differentiation of AM-hMSC, so that, NKB is an excellent xenoimplant option for repairing bone tissue defects.

  10. ORISE: Training and Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Instructional Design and Development Training and Qualification Programs Human Subjects Protection Multimedia Applications Health Promotion and Outreach How ORISE is Making a Difference Overview Operating Public Shelters in a Radiation Emergency Training Tools for Healthy Schools ORISE to Support CDC Infectious Disease Initiative ORISE Supports CDC's Know:BRCA Education Initiative CDC Travelers' Health Team Receives Innovation Award for Website Redesign CDC Travelers' Health Mobile App,

  11. Education and Training

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education and Training - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Fuel Cycle Defense Waste Management Programs Advanced

  12. Education Office Housing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Office Housing Housing A housing forum and listings for housing in and around Los Alamos. Contact Postdoc Housing Email LANL Students' Association Email LANL postdoc program housing The LANL Postdoc Program has a Postdoc Housing listing. If you are interested in posting a housing opportunity, send an email with the pertinent information to postdocprogram@lanl.gov. Housing listings will be posted for 1 month. If you wish for the listing to remain on the web site longer, please contact

  13. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1, 2007 [Education] ARM Sponsors Barrow Teachers to Attend NSTA Conference Bookmark and Share Beginning March 29, 2007, teachers from across the United States will flock to Saint Louis, Missouri, to attend an annual conference hosted by the National Science Teacher's Association. This year, the ARM Program will sponsor two teachers from the North Slope of Alaska to attend the conference as part of an International Polar Year (IPY) outreach effort. Several workshops and symposia related to the

  14. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4, 2006 [Education] ARM Scientists Visit Darwin Schools During the Tropical Warm Pool - International Cloud Experiment Bookmark and Share ARM scientists and graduate students visited a classroom at Wagaman Primary School in Darwin during the two-month TWP-ICE field campaign. Many students and teachers in the Darwin community received first-hand information about ARM research and the exciting Tropical Warm Pool-International Cloud Experiment that took place in January and February this year. ARM

  15. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    July 8, 2005 [Education] EarthStorm Weather Institute Set for July 18-21 Bookmark and Share The Oklahoma Climatological Survey (OCS) will host the EarthStorm Weather Institute July 18-21 at the University of Oklahoma in Norman, Oklahoma. This free four-day workshop will give K-12 teachers an opportunity to investigate weather and improve their skills in preparing students to design and implement science fair projects. For more information, see the EarthStorm website

  16. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    April 5, 2005 [Education] Oklahoma Climatological Survey (OCS) Hosts 12th Annual Atmospheric Radiation Measurement (ARM)/Mesonet Science Fair Bookmark and Share Students look at science projects at the Oklahoma Climatological Survey science fair in February. This year's best-of-show project on renewable energy. The Oklahoma Climatological Survey (OCS) hosted its 12th annual Atmospheric Radiation Measurement (ARM)/Mesonet Science Fair in February 2005. Nearly 100 students from across the state of

  17. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ARM's Contribution to North Slope Science Standards Bookmark and Share While on the North Slope in November 2002, ARM Education staff Carrie Talus and Laura Marsh held a meeting with the North Slope Borough School District's Science Committee, headed by Jodi Picou, in order to discuss adding the subject of climate change to the North Slope science standards. This science committee is working to update and improve the current science standards so that they better match the state and national

  18. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    October 14, 2014 [Education] Conversational Climate Change Bookmark and Share Doug Sisterson Doug Sisterson In order to help their fellow scientists and the general public have science-based conversations with their families and communities about climate change, Doug Sisterson, a long time ARM Climate Research Facility team member, and his colleague, Seth Darling, have written a short book that takes a humorous, conversational style approach to the often hyper-technical and jargon-filled topic

  19. GREEN BANK TELESCOPE ZPECTROMETER CO(1-0) OBSERVATIONS OF THE STRONGLY LENSED SUBMILLIMETER GALAXIES FROM THE HERSCHEL ATLAS

    SciTech Connect (OSTI)

    Frayer, D. T.; Maddalena, R.; Harris, A. I.; Baker, A. J.; Ivison, R. J.; Smail, Ian; Negrello, M.; Aretxaga, I.; Baes, M.; Birkinshaw, M.; Bonfield, D. G.; Burgarella, D.; Buttiglione, S.; Cava, A.; Cooray, A.; Dannerbauer, H.

    2011-01-10

    The Herschel Astrophysical Terahertz Large Area Survey (H-ATLAS) has uncovered a population of strongly lensed submillimeter galaxies (SMGs). The Zpectrometer instrument on the Green Bank Telescope (GBT) was used to measure the redshifts and constrain the masses of the cold molecular gas reservoirs for two candidate high-redshift lensed sources. We derive CO(1-0) redshifts of z = 3.042 {+-} 0.001 and z = 2.625 {+-} 0.001, and measure molecular gas masses of (1-3) x10{sup 10} M{sub sun}, corrected for lens amplification and assuming a conversion factor of {alpha} = 0.8 M{sub sun}( K km s{sup -1} pc{sup 2}){sup -1}. We find typical L(IR)/L'(CO) ratios of 120 {+-} 40 and 140 {+-} 50 L{sub sun}( K km s{sup -1} pc{sup 2}){sup -1}, which are consistent with those found for local ultraluminous infrared galaxies (ULIRGs) and other high-redshift SMGs. From analysis of published data, we find no evidence for enhanced L(IR)/L'(CO(1-0)) ratios for the SMG population in comparison to local ULIRGs. The GBT results highlight the power of using the CO lines to derive blind redshifts, which is challenging for the SMGs at optical wavelengths given their high obscuration.

  20. A program to develop the domestic natural gas industry in Indonesia: Case history of two World Bank projects

    SciTech Connect (OSTI)

    Klass, D.L. ); Khwaja, S. )

    1991-01-01

    Indonesia depends heavily on revenues from the export of LNG and oil, the availability of which appears to be decreasing. It is therefore making a strong effort to accelerate development of a domestic natural gas industry. A high priority has been given to the conversion of power plants and city gas systems, including local industries and commercial facilities, from liquid fuels to natural gas. This will release more oil for export, help to meet the objectives of Repelita V, and provide substantial environmental benefits. The World Bank recently provided loans to the Indonesian Government for two projects that are aimed at substituting natural gas for oil and manufactured gas in domestic markets. One project involves expansion of the gas distribution systems of Indonesia's natural gas utility (PGN) in three cities: Jakarta and Bogor in Java, and Medan in Sumatra. The project also includes training programs for PGN staff and an energy pricing policy study to be carried out by Indonesia's Ministry of Mines and Energy. The second project involves expansion of the supply of natural gas for Surabaya and twelve other towns in its vicinity in East Java, and further expansion of Medan's supply system. Technical assistance will be provided to enhance the skills ofPGN and the Ministry of Mines and Energy, and a Gas Technology Unit similar to the Institute of Gas Technology will be established at Indonesia's Research and Development Center for Oil and Gas (LEMIGAS) in Jakarta. 14 refs., 3 figs., 11 tabs.

  1. Tubing wastage in fluidized-bed coal combustors (Grimethorpe PFBC (pressurized fluidized-bed combustion) Tube Bank E'')

    SciTech Connect (OSTI)

    Witherell, C.E.

    1989-10-04

    Samples of evaporator tubing from Tube Bank E'' of the Grimethorpe pressurized fluidized-bed combustion (PFBC) facility in the UK were examined in the third of a series of studies being conducted at Lawrence Livermore National Laboratory (LLNL) under sponsorship of the US Department of Energy's Morgantown Energy Technology Center (METC). The program is being conducted to identify the mechanism or mechanisms responsible for metal loss (wastage) of in-bed carbon-steel evaporator tubes in bubbling-bed coal combustors. Results of examination suggest that bed conditions were less aggressive than in previous experiments in this combustor; however, tubing wastage was observed in some samples. Observations made on these tubes are consistent with the hypothesis of tubing wastage proposed in reports of previous LLNL studies conducted under this program that the dominant cause of metal loss is exfoliation of the normally-protective oxide scale by impacting bed particulates. Good correlation was also observed with trends noted earlier that microstructure of the tubing steel plays a role in its wastage response. 12 refs., 29 figs., 3 tabs.

  2. Energy Education Links | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education » For Students & Educators » Energy Education Links Energy Education Links These websites offer educational information about hydrogen and fuel cell technologies. American Hydrogen Association - This site includes an educational section called Hydrogen Students as well as related features called Build Your Own Fuel Cell and Think Hydrogen. California Energy Commission/Energy Quest - This energy education website of the California Energy Commission provides information about all

  3. NREL: Workforce Development and Education Programs - Educational Resources

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Educational Resources NREL provides a variety of educational resources to help students, teachers, and parents educate their kids about renewable energy and energy efficiency technologies, including hands-on projects and curriculum suggestions for elementary school, middle school, and high school students as well as teachers. Photo of a man and woman working together in a laboratory. They are both wearing safety glasses as they look at a small white box the man is holding. Elementary School

  4. The Department of Energy Hosts Its First STEM in Indian Country...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    industry, educational advocacy groups, and other federal agencies including NASA and NSF. This series, spearheaded by the Department of Energy's Office of Economic...

  5. Human gingiva-derived mesenchymal stem cells are superior to bone marrow-derived mesenchymal stem cells for cell therapy in regenerative medicine

    SciTech Connect (OSTI)

    Tomar, Geetanjali B.; Srivastava, Rupesh K.; Gupta, Navita; Barhanpurkar, Amruta P.; Pote, Satish T.; Jhaveri, Hiral M.; Mishra, Gyan C.; Wani, Mohan R.

    2010-03-12

    Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation into multiple cell lineages. Presently, bone marrow is considered as a prime source of MSCs; however, there are some drawbacks and limitations in use of these MSCs for cell therapy. In this study, we demonstrate that human gingival tissue-derived MSCs have several advantages over bone marrow-derived MSCs. Gingival MSCs are easy to isolate, homogenous and proliferate faster than bone marrow MSCs without any growth factor. Importantly, gingival MSCs display stable morphology and do not loose MSC characteristic at higher passages. In addition, gingival MSCs maintain normal karyotype and telomerase activity in long-term cultures, and are not tumorigenic. Thus, we reveal that human gingiva is a better source of MSCs than bone marrow, and large number of functionally competent clinical grade MSCs can be generated in short duration for cell therapy in regenerative medicine and tissue engineering.

  6. WINDExchange: Education and Workforce Development

    Wind Powering America (EERE)

    Education Printable Version Bookmark and Share Workforce Development Collegiate Wind Competition Wind for Schools Project School Project Locations Education & Training Programs Curricula & Teaching Materials Resources Education and Workforce Development WINDExchange offers resources for anyone wishing to learn about wind energy at any level. Learn about workforce development initiatives, including the U.S. Department of Energy Collegiate Wind Competition, the Wind for Schools project,

  7. WINDExchange: Education and School Resources

    Wind Powering America (EERE)

    Education and School Resources Filter the WINDExchange database for information resources about Wind for Schools, education and training programs, news, and educational links. Search the WINDExchange Database Choose a Type of Information All News Publications Web Resource Videos Start Search Clear Search Date State Type of Information Program Area Title 5/23/2016 DC News Schools Small Wind Energy Department Announces Partnership with DWEA to Support Wind for Schools Project 1/12/2016 News

  8. Educational Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Educational Resources Educational Resources Sixth graders at Old Mill Middle School North experiment with steam to understand clean, natural geothermal energy from the Earth. Sixth graders at Old Mill Middle School North experiment with steam to understand clean, natural geothermal energy from the Earth. Geothermal Education Resources Geothermal Basics explained in plain language. Geothermal Resource of the United States: Map from the National Renewable Energy Lab. Energy Kids - Geothermal.

  9. ORISE Science Education Programs: Capabilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Capabilities Science Education Programs Capabilities The Oak Ridge Institute for Science and Education (ORISE) connects the best and most diverse students and faculty members to programs closely aligned with the interests of a variety of research facilities, including those managed for the U.S. Department of Energy (DOE) and more than a dozen other federal agencies. Current ORISE science education program opportunities include: Undergraduate scholarships Graduate fellowships Postgraduate

  10. PIA - INL Education Programs Business Enclave | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education Programs Business Enclave PIA - INL Education Programs Business Enclave PIA - INL Education Programs Business Enclave PDF icon PIA - INL Education Programs Business ...

  11. X-Ray Science Education

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TV Network external link DNA Interactive external link Reciprocal Net external link X-ray Science Courses and Programs Various educational efforts are closely related to the...

  12. Education Blog | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    approaches to environmental education in their schools August 6, 2014 Ronald J. (R.J.) McIntosh receives a Certificate of Special Congressional Recognition from Rep. Suzan...

  13. NREL: Education Center - Webmaster

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Webmaster To contact the Webmaster, please provide your name, e-mail address, and message below. When you are finished, click "Send Message." NOTE: If you enter your e-mail address incorrectly, we will be unable to reply. Your name: Your email address: Your message: Send Message Printable Version Education Center Home Hours, Directions & Contact Information Group Programs A Model of Energy-Efficient Design Did you find what you needed? Yes 1 No 0 Thank you for your feedback. Would

  14. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4, 2007 [Education] Oklahoma Science Fair: The Results are In! Bookmark and Share Parker Stambaugh, a seventh-grader, won first place with his experiment, "Still Breathing Easy." On February 24, 2007, two students walked away from the Oklahoma Mesonet/ARM Science Fair with a trophy in-hand. Parker Stambaugh, a seventh-grader at Emerson Junior High in Enid, and Giezi Flores, a sixth-grader from Monroe Elementary in Enid, were first-place winners in the upper and lower divisions,

  15. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    January 26, 2007 [Education] Oklahoma Students Gear Up for 15th Annual Oklahoma Mesonet/ARM Science Fair Bookmark and Share For the past 15 years, Oklahoma students have competed for Best in Show honors at the annual Oklahoma Mesonet/ARM Science Fair. This year, the science fair will be exceptionally exciting as it has been named an official centennial event. Oklahoma is celebrating 100 years of statehood, and students will do their best to showcase the state's enthusiasm for weather and climate

  16. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1, 2006 [Education] Students Tour the SGP Facility Bookmark and Share Seventh graders tour the ARM SGP site in November. On November 1, 2006, the SGP site hosted a group of 30 seventh graders from the local Deer Creek-Lamont school district. The students and their teacher, Deborah McFeeters, were on a mission to learn about the ARM Program and the exciting research taking place at the SGP site. SGP Operations Manager Dan Rusk gave a slide presentation about ARM and lead the group on a short

  17. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    January 16, 2004 [Education] Coastal Erosion: What is it, How is it Related to Climate Change and Why Should We Care? Bookmark and Share Recently the term "coastal erosion" has been popping up in the news, but what does it mean? If you look up the word erosion in the dictionary, it references the root word "erode," which means to "eat into, wear away, or disintegrate." So coastal erosion is erosion that occurs along coastlines. With about half of the population of

  18. ARM - Education Article

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Climate Change Kiosk Opening Ceremony Bookmark and Share People view the new ARM Climate Change Kiosk at the NSA site. The ARM Education and Outreach team had a very successful trip to the North Slope of Alaska (NSA) in October. The main purpose of the trip was to dedicate the new interactive kiosk titled "Climate Change: Science and Traditional Knowledge," now on permanent display at the Iñupiat Heritage Center (IHC) in Barrow, Alaska. The kiosk is a unique opportunity for people to

  19. Education Highlights: Gasoline Compression Ignition | Argonne National

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Blog Education Blog The Office of Energy Efficiency and Renewable Energy's (EERE) education blog page highlights the initiatives, achievements and student competition results across all EERE technology offices including Solar, Wind & Water, Bioenergy, Vehicles, Geothermal, Hydrogen & Fuel Cells, Advanced Manufacturing, Homes, Buildings, and Government Energy Management. Blogs featured on this section of the education site announce educational opportunities including internships

  20. Differentiation within autologous fibrin scaffolds of porcine dermal cells with the mesenchymal stem cell phenotype

    SciTech Connect (OSTI)

    Puente, Pilar de la

    2013-02-01

    Porcine mesenchymal stem cells (pMSCs) are an attractive source of cells for tissue engineering because their properties are similar to those of human stem cells. pMSCs can be found in different tissues but their dermal origin has not been studied in depth. Additionally, MSCs differentiation in monolayer cultures requires subcultured cells, and these cells are at risk of dedifferentiation when implanting them into living tissue. Following this, we attempted to characterize the MSCs phenotype of porcine dermal cells and to evaluate their cellular proliferation and differentiation in autologous fibrin scaffolds (AFSs). Dermal biopsies and blood samples were obtained from 12 pigs. Dermal cells were characterized by flow cytometry. Frozen autologous plasma was used to prepare AFSs. pMSC differentiation was studied in standard structures (monolayers and pellets) and in AFSs. The pMSCs expressed the CD90 and CD29 markers of the mesenchymal lineage. AFSs afforded adipogenic, osteogenic and chondrogenic differentiation. The porcine dermis can be proposed to be a good source of MSCs with adequate proliferative capacity and a suitable expression of markers. The pMSCs also showed optimal proliferation and differentiation in AFSs, such that these might serve as a promising autologous and implantable material for use in tissue engineering. -- Highlights: ► Low fibrinogen concentration provides a suitable matrix for cell migration and differentiation. ► Autologous fibrin scaffolds is a promising technique in tissue engineering. ► Dermal cells are an easily accessible mesenchymal stem cell source. ► Fibrin scaffolds afforded adipogenic, osteogenic and chondrogenic differentiation.

  1. Different origin of adipogenic stem cells influences the response to antiretroviral drugs

    SciTech Connect (OSTI)

    Gibellini, Lara; De Biasi, Sara; Nasi, Milena; Carnevale, Gianluca; Pisciotta, Alessandra; Bianchini, Elena; Bartolomeo, Regina; Polo, Miriam; De Pol, Anto; Pinti, Marcello; Cossarizza, Andrea

    2015-10-01

    Lipodystrophy (LD) is a main side effect of antiretroviral therapy for HIV infection, and can be provoked by nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs). LD exists in different forms, characterized by fat loss, accumulation, or both, but its pathogenesis is still unclear. In particular, few data exist concerning the effects of antiretroviral drugs on adipocyte differentiation. Adipose tissue can arise either from mesenchymal stem cells (MSCs), that include bone marrow-derived MSCs (hBM-MSCs), or from ectodermal stem cells, that include dental pulp stem cells (hDPSCs). To analyze whether the embryonal origin of adipocytes might impact the occurrence of different phenotypes in LD, we quantified the effects of several antiretroviral drugs on the adipogenic differentiation of hBM-MSCs and hDPSCs. hBM-MSCs and hDPSCs were isolated from healthy donors. Cells were treated with 10 and 50 μM stavudine (d4T), efavirenz (EFV), atazanavir (ATV), ritonavir (RTV), and ATV-boosted RTV. Viability and adipogenesis were evaluated by staining with propidium iodide, oil red, and adipoRed; mRNA levels of genes involved in adipocyte differentiation, i.e. CCAAT/enhancer-binding protein alpha (CEBPα) and peroxisome proliferator-activated receptor gamma (PPARγ), and in adipocyte functions, i.e. fatty acid synthase (FASN), fatty acid binding protein-4 (FABP4), perilipin-1 (PLIN1) and 1-acylglycerol-3-phosphate O-acyltransferase-2 (AGPAT2), were quantified by real time PCR. We found that ATV, RTV, EFV, and ATV-boosted RTV, but not d4T, caused massive cell death in both cell types. EFV and d4T affected the accumulation of lipid droplets and induced changes in mRNA levels of genes involved in adipocyte functions in hBM-MSCs, while RTV and ATV had little effects. All drugs stimulated the accumulation of lipid droplets in hDPSCs. Thus, the adipogenic differentiation of human stem cells can be influenced by antiretroviral drugs, and depends, at least in part, on their embryonal origin. - Highlights: • ATV, RTV, EFV and ATV-boosted RTV induce massive cell death in hBM-MSCs and hDPSCs. • EFV and d4T strongly affect the accumulation of lipid droplets in hBM-MSCs. • All drugs stimulate the accumulation of lipid droplets in hDPSCs.

  2. Argonne event encourages young women to pursue careers in STEM | Argonne

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Leadership Computing Facility Argonne event encourages young women to pursue careers in STEM Author: Jim Collins April 21, 2016 Facebook Twitter LinkedIn Google E-mail Printer-friendly version Francesca Restani, a 16-year-old student at Lyons Township High School, was ecstatic when she found out she would be touring the Argonne Leadership Computing Facility (ALCF) as part of Argonne's Science Careers in Search of Women (SCSW) event on April 14. "I was just hoping I would learn something

  3. Education Roadmap for Mining Professionals

    SciTech Connect (OSTI)

    none,

    2002-12-01

    This document represents the roadmap for education in the U.S. mining industry. It was developed based on the results of an Education Roadmap Workshop sponsored by the National Mining Association in conjunction with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Office of Industrial Technologies. The Workshop was held February 23, 2002 in Phoenix, Arizona.

  4. Human Genome Education Program

    SciTech Connect (OSTI)

    Richard Myers; Lane Conn

    2000-05-01

    The funds from the DOE Human Genome Program, for the project period 2/1/96 through 1/31/98, have provided major support for the curriculum development and field testing efforts for two high school level instructional units: Unit 1, ''Exploring Genetic Conditions: Genes, Culture and Choices''; and Unit 2, ''DNA Snapshots: Peaking at Your DNA''. In the original proposal, they requested DOE support for the partial salary and benefits of a Field Test Coordinator position to: (1) complete the field testing and revision of two high school curriculum units, and (2) initiate the education of teachers using these units. During the project period of this two-year DOE grant, a part-time Field-Test Coordinator was hired (Ms. Geraldine Horsma) and significant progress has been made in both of the original proposal objectives. Field testing for Unit 1 has occurred in over 12 schools (local and non-local sites with diverse student populations). Field testing for Unit 2 has occurred in over 15 schools (local and non-local sites) and will continue in 12-15 schools during the 96-97 school year. For both curricula, field-test sites and site teachers were selected for their interest in genetics education and in hands-on science education. Many of the site teachers had no previous experience with HGEP or the unit under development. Both of these first-year biology curriculum units, which contain genetics, biotechnology, societal, ethical and cultural issues related to HGP, are being implemented in many local and non-local schools (SF Bay Area, Southern California, Nebraska, Hawaii, and Texas) and in programs for teachers. These units will reach over 10,000 students in the SF Bay Area and continues to receive support from local corporate and private philanthropic organizations. Although HGEP unit development is nearing completion for both units, data is still being gathered and analyzed on unit effectiveness and student learning. The final field testing result from this analysis will contribute to the final revisions of each unit during the second-year of this grant.

  5. Synchrophasor Engineering Education Program Project Summaries...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Synchrophasor Engineering Education Program Project Summaries Available Synchrophasor Engineering Education Program Project Summaries Available July 9, 2014 - 10:48am Addthis On...

  6. DOE Solar Training and Education for Professionals

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy (DOE) Solar Training and Education for Professionals (STEP) funding opportunity will support many activities in solar training and education.

  7. CMI Education and Outreach | Critical Materials Institute

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2015, September 2015 and December 2015. Office of Special Programs & Continuing Education (SPACE) offers a variety of educational programs for industry, K-12 and university....

  8. Education and Training | Department of Energy

    Energy Savers [EERE]

    Education and Training The DOE Office of Indian Energy is working to build tribal energy capacity by providing education and training resources such as renewable energy...

  9. Innovative Drivetrains in Electric Automotive Technology Education...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Drivetrains in Electric Automotive Technology Education (IDEATE) Innovative Drivetrains in Electric Automotive Technology Education (IDEATE) 2012 DOE Hydrogen and Fuel Cells ...

  10. NREL: Education Programs - K-12 Students

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    K-12 Students NREL's Education Programs seek to promote science, mathematics, and technology education using renewable energy as the vehicle to capture student interest. Engaging...

  11. Lumens Education Poster | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The new way to shop for light. Energysaver.gov.' More Documents & Publications Goodbye, Watts. Hello, Lumens. (Low-Resolution Billboard) Lumens Education Poster Lumens Education ...

  12. Funding Opportunity Announcement: Solar Training and Education...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Training and Education for Professionals (STEP) Funding Opportunity Announcement: Solar Training and Education for Professionals (STEP) Funding Number: DE-FOA-0001329 Funding ...

  13. Education and Workforce Development | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Workforce Development Education and Workforce Development bioenergizeHeader480.png ... OPERATION BioenergizeME is the Bioenergy Technologies Office's (BETO's) education and ...

  14. Lumens Education Poster | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The new way to shop for light. Energysaver.gov.' PDF icon lumenseducationposter.pdf More Documents & Publications Lumens Education Poster - EPS Lumens Education Poster Goodbye, ...

  15. Vehicle Technologies Office: Education and Workforce Development...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education and Workforce Development Vehicle Technologies Office: Education and Workforce Development The Vehicle Technologies Office (VTO) offers a variety of resources and ...

  16. Education Staff Directory | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cantu, Emily Educational Outreach Programs emancini@anl.gov Domyancich, John Learning Lab Coordinator jdomyancich@anl.gov Ettinger, Deon Educator Emeritus...

  17. When will low-contrast features be visible in a STEM X-ray spectrum image?

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Parish, Chad M.

    2015-02-03

    When will a small or low-contrast feature, such as an embedded second-phase particle, be visible in a scanning transmission electron microscopy (STEM) X-ray map? This work illustrates a computationally inexpensive method to simulate X-ray maps and spectrum images (SIs), based upon the equations of X-ray generation and detection. To particularize the general procedure, an example of nanostructured ferritic alloy (NFA) containing nm-sized Y2Ti2O7 embedded precipitates in ferritic stainless steel matrix is chosen. The proposed model produces physically appearing simulated SI data sets, which can either be reduced to X-ray dot maps or analyzed via multivariate statistical analysis. Comparison to NFAmore » X-ray maps acquired using three different STEM instruments match the generated simulations quite well, despite the large number of simplifying assumptions used. A figure of merit of electron dose multiplied by X-ray collection solid angle is proposed to compare feature detectability from one data set (simulated or experimental) to another. The proposed method can scope experiments that are feasible under specific analysis conditions on a given microscope. As a result, future applications, such as spallation proton–neutron irradiations, core-shell nanoparticles, or dopants in polycrystalline photovoltaic solar cells, are proposed.« less

  18. Thymosin beta-4 promotes mesenchymal stem cell proliferation via an interleukin-8-dependent mechanism

    SciTech Connect (OSTI)

    Jeon, Byung-Joon; Yang, Yoolhee; Kyung Shim, Su; Yang, Heung-Mo; Cho, Daeho; Ik Bang, Sa

    2013-10-15

    Mesenchymal stem cells (MSCs) hold great promise for the field of tissue regeneration. Because only a limited number of MSCs can be obtained from each donor site, it is important to establish standard methods for MSC expansion using growth and trophic factors. Thymosin ?4 (T?4) is a novel trophic factor that has antimicrobial effects and the potential to promote tissue repair. T?4 is a ubiquitous, naturally-occurring peptide in the wound bed. Therefore, the relationship between T?4 and MSCs, especially adjacent adipose tissue-derived stem cells (ASCs), merits consideration. Exogenous T?4 treatment enhanced the proliferation of human ASCs, resulting in prominent nuclear localization of PCNA immunoreactivity. In addition, exogenous T?4 also increased IL-8 secretion and blocking of IL-8 with neutralizing antibodies decreased T?4-induced ASC proliferation, suggesting that IL-8 is a critical mediator of T?4-enhanced proliferation. Moreover, T?4 activated phosphorylation of ERK1/2 and increased the nuclear translocation of NF-?B. These observation provide that T?4 promotes the expansion of human ASCs via an IL-8-dependent mechanism that involves the ERK and NF-?B pathways. Therefore, T?4 could be used as a tool for MSC expansion in cell therapeutics. - Highlights: This is fundamental information required to correlate T?4 with MSC expansion. MSC expansion by T?4 is involved in enhancement of IL-8 and ERK/NF-?B pathway. T?4 could be used as a tool for MSC expansion in cell therapeutics.

  19. When will low-contrast features be visible in a STEM X-ray spectrum image?

    SciTech Connect (OSTI)

    Parish, Chad M.

    2015-02-03

    When will a small or low-contrast feature, such as an embedded second-phase particle, be visible in a scanning transmission electron microscopy (STEM) X-ray map? This work illustrates a computationally inexpensive method to simulate X-ray maps and spectrum images (SIs), based upon the equations of X-ray generation and detection. To particularize the general procedure, an example of nanostructured ferritic alloy (NFA) containing nm-sized Y2Ti2O7 embedded precipitates in ferritic stainless steel matrix is chosen. The proposed model produces physically appearing simulated SI data sets, which can either be reduced to X-ray dot maps or analyzed via multivariate statistical analysis. Comparison to NFA X-ray maps acquired using three different STEM instruments match the generated simulations quite well, despite the large number of simplifying assumptions used. A figure of merit of electron dose multiplied by X-ray collection solid angle is proposed to compare feature detectability from one data set (simulated or experimental) to another. The proposed method can scope experiments that are feasible under specific analysis conditions on a given microscope. As a result, future applications, such as spallation proton–neutron irradiations, core-shell nanoparticles, or dopants in polycrystalline photovoltaic solar cells, are proposed.

  20. Novel application of stem cell-derived factors for periodontal regeneration

    SciTech Connect (OSTI)

    Inukai, Takeharu; Katagiri, Wataru; Yoshimi, Ryoko; Osugi, Masashi; Kawai, Takamasa; Hibi, Hideharu; Ueda, Minoru

    2013-01-11

    Highlights: Black-Right-Pointing-Pointer Mesenchymal stem cells (MSCs) secrete a variety of cytokines. Black-Right-Pointing-Pointer Cytokines were detected in conditioned medium from cultured MSCs (MSC-CM). Black-Right-Pointing-Pointer MSC-CM enhanced activation of dog MSCs and periodontal ligament cells. Black-Right-Pointing-Pointer MSC-CM significantly promoted alveolar bone and cementum regeneration. Black-Right-Pointing-Pointer Multiple cytokines contained in MSC-CM promote periodontal regeneration. -- Abstract: The effect of conditioned medium from cultured mesenchymal stem cells (MSC-CM) on periodontal regeneration was evaluated. In vitro, MSC-CM stimulated migration and proliferation of dog MSCs (dMSCs) and dog periodontal ligament cells (dPDLCs). Cytokines such as insulin-like growth factor, vascular endothelial growth factor, transforming growth factor-{beta}1, and hepatocyte growth factor were detected in MSC-CM. In vivo, one-wall critical-size, intrabony periodontal defects were surgically created in the mandible of dogs. Dogs with these defects were divided into three groups that received MSC-CM, PBS, or no implants. Absorbable atelo-collagen sponges (TERUPLUG Registered-Sign ) were used as a scaffold material. Based on radiographic and histological observation 4 weeks after transplantation, the defect sites in the MSC-CM group displayed significantly greater alveolar bone and cementum regeneration than the other groups. These findings suggest that MSC-CM enhanced periodontal regeneration due to multiple cytokines contained in MSC-CM.

  1. Pyrolytic oil of banana (Musa spp.) pseudo-stem via fast process

    SciTech Connect (OSTI)

    Abdullah, Nurhayati; Sulaiman, Fauziah; Taib, Rahmad Mohd; Miskam, Muhamad Azman

    2015-04-24

    This study was an attempt to produce bio-oil from banana pseudo-stem, a waste of banana cultivation, using fast pyrolysis technology. The compositions were determined and the thermal degradation behaviour of the raw material was analyzed using Perkin-Elmer Simultaneous Thermal Analyzer (STA) 6000. A 300 g/h fluidized bed bench scale fast pyrolysis unit, assembled with double screw feeders and cyclones, operating at atmospheric pressure, was used to obtain the pyrolysis liquid. The study involves the impact of the following key variables; the reactor temperature in the range of 450–650 °C, and the residence time in the range of 1.00–3.00 s. The particle size was set at 224-400 µm. The properties of the liquid product were analyzed for calorific heating value, pH value, conductivity, water and char content. The basic functional groups of the compositions were also determined using FTIR. The properties of the liquid product were compared with other wood derived bio-oil. The pyrolysis liquids derived from banana pseudo-stem were found to be in an aqueous phase.

  2. STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH{sup +}/CD133{sup +} stem cell-like human colon cancer cells

    SciTech Connect (OSTI)

    Lin, Li; Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 ; Fuchs, James; Li, Chenglong; Olson, Veronica; Bekaii-Saab, Tanios; Lin, Jiayuh

    2011-12-16

    Highlights: Black-Right-Pointing-Pointer The phosphorylated or activated form of STAT3 was expressed in colon cancer stem-like cells. Black-Right-Pointing-Pointer STAT3 inhibitor, FLLL32 inhibits P-STAT3 and STAT3 target genes in colon cancer stem-like cells. Black-Right-Pointing-Pointer Inhibition of STAT3 resulted in decreased cell viability and reduced numbers of tumorspheres. Black-Right-Pointing-Pointer STAT3 is required for survival and tumorsphere forming capacity in colon cancer stem-like cells. Black-Right-Pointing-Pointer Targeting STAT3 in cancer stem-like cells may offer a novel treatment approach for colon cancer. -- Abstract: Persistent activation of Signal Transducers and Activators of Transcription 3 (STAT3) is frequently detected in colon cancer. Increasing evidence suggests the existence of a small population of colon cancer stem or cancer-initiating cells may be responsible for tumor initiation, metastasis, and resistance to chemotherapy and radiation. Whether STAT3 plays a role in colon cancer-initiating cells and the effect of STAT3 inhibition is still unknown. Flow cytometry was used to isolate colon cancer stem-like cells from three independent human colon cancer cell lines characterized by both aldehyde dehydrogenase (ALDH)-positive and CD133-positive subpopulation (ALDH{sup +}/CD133{sup +}). The effects of STAT3 inhibition in colon cancer stem-like cells were examined. The phosphorylated or activated form of STAT3 was expressed in colon cancer stem-like cells and was reduced by a STAT3-selective small molecular inhibitor, FLLL32. FLLL32 also inhibited the expression of potential STAT3 downstream target genes in colon cancer stem-like cells including survivin, Bcl-XL, as well as Notch-1, -3, and -4, which may be involved in stem cell function. Furthermore, FLLL32 inhibited cell viability and tumorsphere formation as well as induced cleaved caspase-3 in colon cancer stem-like cells. FLLL32 is more potent than curcumin as evidenced with lower IC50 in colon cancer stem-like cells. In summary, our results indicate that STAT3 is a novel therapeutic target in colon cancer stem-like cells and inhibition of STAT3 in cancer stem-like cells may offer a potential treatment for colorectal cancer.

  3. Stromatolites, ooid dunes, hardgrounds, and crusted mud beds, all products of marine cementation and microbial mats in subtidal oceanic mixing zone on eastern margin of Great Bahama Bank

    SciTech Connect (OSTI)

    Dill, R.F.; Kendall, C.S.C.G.; Steinen, R.P.

    1989-03-01

    The interisland channels along the eastern margin of the Great Bahamas Bank contain lithified structures that owe their origin to recent marine cementation. This cementation appears to be commonly associated with a complex microbial community of plants and microorganisms living within a bank-margin oceanographic mixing zone. In this region, reversing tidal and wind-driven currents flow up to 3 knots (150 cm/sec) three hours out of each six-hour tidal period. Here, marine-cement crusted, carbonate mud beds are found interbedded within migrating ooid sand bars and dunes and are associated with growing, lithified stromatolites up to 2 m in height. These laminated mud beds are found with thicknesses of up to 1 m in subtidal depths of 4 to 8 m (12 to 25 ft). The muds appear to be homogeneous, but closer examination by SEM and under a microscope reveals they are composed of pelletoid aggregates of needle-shaped aragonite crystals with diameters of up to 50 ..mu... The size of these soft pellets is similar to the smaller grains of ooid sands that are abundant in the area. This size similarity could explain why both the mud beds are found in similar high-energy hydraulic regimes as the ooid sands, but does not suggest how or why the aggregates of pure aragonite needles form. A high production of ooid sand within this bank margin environment permits the formation of natural levees along the margins of tidal channels. The back sides of these levees are being lithified by marine cements to form hardgrounds. Skeletal and ooid sand dunes stabilized by Thallasia in channel bottoms also are becoming lithified. Grapestones form at the distributaries of flood tidal deltas of ooid sand. All of these features have a common attribute: they are continually in contact with the turbulent mixing-zone waters.

  4. Westinghouse to host education fair

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to Host Education Fair CARLSBAD, N.M., June 8, 2000 - The Westinghouse Waste Isolation Division (WID) invites the public to participate in an education fair June 14 in Carlsbad. The event is scheduled from 8 a.m. until noon and from 1:30 p.m. until 3 p.m. at the Skeen-Whitlock Building, 4021 National Parks Highway. Representatives from 10 universities will be on hand to discuss degree programs available through distance education. Persons interested in pursuing undergraduate and graduate degrees

  5. NY Green Bank

    Broader source: Energy.gov (indexed) [DOE]

    capital markets for large scale infrastructure are deep and robust. These markets enjoy economies of scale with low relative transaction costs and well-understood risk. These...

  6. Longwall data bank

    SciTech Connect (OSTI)

    Not Available

    1982-03-01

    Sixteen longwall questionnaires were received from operators and two additional longwalls were added to the questionnaire file. Data from questionnaires were tabulated and analyzed. Relevant coal mining publications were reviewed for longwall references and 25 were added to the index file. Fifteen abstracts from selected R and D reports and professional journal articles were prepared.

  7. OCT4A contributes to the stemness and multi-potency of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs)

    SciTech Connect (OSTI)

    Seo, Kwang-Won; Lee, Sae-Rom; Bhandari, Dilli Ram; Roh, Kyoung-Hwan; Park, Sang-Bum; So, Ah-Young; Jung, Ji-Won; Seo, Min-Soo; Laboratory of Stem Cell and Tumor Biology, Department of Veterinary Public Health, College of Veterinary Medicine, and BK21 Program for Veterinary Science, Seoul National University 151-742, Seoul ; Kang, Soo-Kyung; Laboratory of Biotechnology, College of Veterinary Medicine, and BK21 Program for Veterinary Science, Seoul National University 151-742, Seoul ; Lee, Yong-Soon; Laboratory of Stem Cell and Tumor Biology, Department of Veterinary Public Health, College of Veterinary Medicine, and BK21 Program for Veterinary Science, Seoul National University 151-742, Seoul ; Kang, Kyung-Sun; Laboratory of Stem Cell and Tumor Biology, Department of Veterinary Public Health, College of Veterinary Medicine, and BK21 Program for Veterinary Science, Seoul National University 151-742, Seoul

    2009-06-19

    The OCT4A gene, a POU homeodomain transcription factor, has been shown to be expressed in embryonic stem cells (ESC) as well as hUCB-MSCs. In this study, the roles played by OCT4A in hUCB-MSCs were determined by stably inhibiting OCT4A with lenti-viral vector-based small hairpin RNA (shRNA). A decreased rate of cell proliferation was observed in OCT4-inhibited hUCB-MSCs. Down-regulation of CCNA2 expression in OCT4-inhibited hUCB-MSCs was confirmed by RT-PCR and real-time RT-PCR analysis in three genetically independent hUCB-MSC clones. Adipogenic differentiation was also suppressed in OCT4-inhibited hUCB-MSCs. The up-regulation of DTX1 and down-regulation of HDAC1, 2, and 4 expressions may be related to this differentiation deformity. The expression of other transcription factors, including SOX2, REX1 and c-MYC, was also affected by OCT4 inhibition in hUCB-MSCs. In conclusion, these finding suggest that OCT4A performs functionally conserved roles in hUCB-MSCs, making its expression biologically important for ex vivo culture of hUCB-MSCs.

  8. NREL: Workforce Development and Education Programs - News Release...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A national organization devoted to getting more Hispanics into the fields of science, technology, engineering, and math (STEM), has honored a scientist at the Energy Department's ...

  9. Vehicle Technologies Office: Graduate Automotive Technology Education

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    (GATE) | Department of Energy Education & Workforce Development » Vehicle Technologies Office: Graduate Automotive Technology Education (GATE) Vehicle Technologies Office: Graduate Automotive Technology Education (GATE) DOE established the Graduate Automotive Technology Education (GATE) Centers of Excellence to provide future generations of engineers and scientists with knowledge and skills in advanced automotive technologies. By funding curriculum development and expansion as well as

  10. Science Education Group | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Education Group View larger image Sci Ed Group 15 View larger image Group 21

  11. Donation Improves Nuclear Training, Education

    Broader source: Energy.gov [DOE]

    RICHLAND, Wash. – A $32,000 donation from Washington River Protection Solutions (WRPS), the Hanford Tank Operations Contractor for EM’s Office of River Protection, is improving nuclear training and education at a local community college.

  12. NGF induces adult stem Leydig cells to proliferate and differentiate during Leydig cell regeneration

    SciTech Connect (OSTI)

    Zhang, Lei; Wang, Huaxi; Yang, Yan; Liu, Hui; Zhang, Qihao; Xiang, Qi; National Engineering Research Center of Genetic Medicine, 510632 Guangzhou ; Ge, Renshan; Su, Zhijian; Huang, Yadong; National Engineering Research Center of Genetic Medicine, 510632 Guangzhou

    2013-06-28

    Highlights: Nerve growth factor has shown significant changes on mRNA levels during Adult Leydig cells regeneration. We established the organ culture model of rat seminiferous tubules with ethane dimethyl sulphonate (EDS) treatment. Nerve growth factor has shown proliferation and differentiation-promoting effects on Adult stem Leydig cells. Nerve growth factor induces progenitor Leydig cells to proliferate and differentiate and immature Leydig cells to proliferate. -- Abstract: Nerve growth factor (NGF) has been reported to be involved in male reproductive physiology. However, few reports have described the activity of NGF during Leydig cell development. The objective of the present study was to examine the role of NGF during stem-Leydig-cell (SLC) regeneration. We investigated the effects of NGF on Leydig-cell (LC) regeneration by measuring mRNA levels in the adult rat testis after ethane dimethanesulfonate (EDS) treatment. Furthermore, we used the established organ culture model of rat seminiferous tubules to examine the regulation of NGF during SLC proliferation and differentiation using EdU staining, real-time PCR and western blotting. Progenitor Leydig cells (PLCs) and immature Leydig cells (ILCs) were also used to investigate the effects of NGF on LCs at different developmental stages. NGF mRNA levels changed significantly during Leydig-cell regeneration in vivo. In vitro, NGF significantly promoted the proliferation of stem Leydig cells and also induced steroidogenic enzyme gene expression and 3?-HSD protein expression. The data from PLCs and ILCs showed that NGF could increase Cyclin D1 and Hsd 17b3 mRNA levels in PLCs and Cyclin D1 mRNA levels in ILCs. These results indicate that NGF may play an important role during LC regeneration by regulating the proliferation and differentiation of LCs at different developmental stages, from SLCs to PLCs and from PLCs to ILCs. The discovery of this effect of NGF on Leydig cells will provide useful information for developing new potential therapies for PADAM (Partial Androgen Deficiency in the Aging Male)

  13. NREL: Education Center Home Page

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Photo of the NREL Education Center. Clean Energy Innovation Programs for Student and Community Groups NREL's Education Center offers a variety of program topics and experiences for student and adult groups addressing renewable energy and energy efficiency innovations and introducing the work of NREL to audiences. A launch-pad for energy innovations, NREL is home to world-renowned energy experts. NREL researches and develops technologies for powering our homes, buildings, and businesses, and

  14. Education | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education Subscribe to RSS - Education The PPPL function that reaches out to students, teachers and the general public through programs ranging from student internships to weekly talks on scientific topics from January through April. Fun and inspiration for 575 young women at PPPL's Young Women's Conference Some 575 seventh- to tenth-grade girls from throughout New Jersey, as well as Pennsylvania and Maryland, found fun and inspiration doing myriad hands-on activities and meeting female

  15. Educational Opportunities in Bioenergy - ORNL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Educational Opportunities in Bioenergy Office of the Biomass Program Webinar April 23, 2012 2 Managed by UT-Battelle for the U.S. Department of Energy ORNL - Educational Opportunities in Bioenergy Agenda Overview of programs - Tim Theiss - Laboratory Relationship Manager, Biomass Program - Oak Ridge National Laboratory * Mentor perspective - Erin Webb, Ph.D., P.E - Research Engineer, Renewable Systems Group - Oak Ridge National Laboratory * Post-graduate perspective - Scott Curran - Research

  16. Cellular interactions via conditioned media induce in vivo nephron generation from tubular epithelial cells or mesenchymal stem cells

    SciTech Connect (OSTI)

    Machiguchi, Toshihiko Nakamura, Tatsuo

    2013-06-07

    Highlights: We have attempted in vivo nephron generation using conditioned media. Vascular and tubular cells do cross-talks on cell proliferation and tubular changes. Tubular cells suppress these changes in mesenchymal stem cells. Tubular cells differentiate mesenchymal stem cells into tubular cells. Nephrons can be created from implanted tubular cells or mesenchymal stem cells. -- Abstract: There are some successful reports of kidney generation by utilizing the natural course of kidney development, namely, the use of an artificially treated metanephros, blastocyst or ureteric bud. Under a novel concept of cellular interactions via conditioned media (CMs), we have attempted in vivo nephron generation from tubular epithelial cells (TECs) or mesenchymal stem cells (MSCs). Here we used 10 CMs of vascular endothelial cells (VECs) and TECs, which is the first to introduce a CM into the field of organ regeneration. We first present stimulative cross-talks induced by these CMs between VECs and TECs on cell proliferation and morphological changes. In MSCs, TEC-CM suppressed these changes, however, induced cytokeratin expression, indicating the differentiation of MSCs into TECs. As a result, glomerular and tubular structures were created following the implantation of TECs or MSCs with both CMs. Our findings suggest that the cellular interactions via CMs might induce in vivo nephron generation from TECs or MSCs. As a promoting factor, CMs could also be applied to the regeneration of other organs and tissues.

  17. For Students and Educators | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Education » For Students and Educators For Students and Educators Whether you're teaching fifth-grade general science or advanced electrochemistry, one of tomorrow's leading hydrogen and fuel cell experts may be sitting in your classroom today. Visit the following links to find educational resources for students and teachers. Grades 5-12 - Lesson plans, visual aids, laboratory experiments, videos, and teacher workshops Higher Education - College-level textbooks, programs, scholarships,

  18. Large-angle illumination STEM: Toward three-dimensional atom-by-atom imaging

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ishikawa, Ryo; Lupini, Andrew R.; Hinuma, Yoyo; Pennycook, Stephen

    2014-11-26

    To completely understand and control materials and their properties, it is of critical importance to determine their atomic structures in all three dimensions. Recent revolutionary advances in electron optics – the inventions of geometric and chromatic aberration correctors as well as electron source monochromators – have provided fertile ground for performing optical depth sectioning at atomic-scale dimensions. In this study we theoretically demonstrate the imaging of top/sub-surface atomic structures and identify the depth of single dopants, single vacancies and the other point defects within materials by large-angle illumination scanning transmission electron microscopy (LAI-STEM). The proposed method also allows us tomore » measure specimen properties such as thickness or three-dimensional surface morphology using observations from a single crystallographic orientation.« less

  19. Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation

    SciTech Connect (OSTI)

    Yamano, Noriko; Kimura, Tohru; Watanabe-Kushima, Shoko; Shinohara, Takashi; Nakano, Toru; Department of Pathology, Medical School, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871

    2010-02-12

    Specification to primordial germ cells (PGCs) is mediated by mesoderm-induction signals during gastrulation. We found that Akt activation during in vitro mesodermal differentiation of embryonic stem cells (ESCs) generated self-renewing spheres with differentiation states between those of ESCs and PGCs. Essential regulators for PGC specification and their downstream germ cell-specific genes were expressed in the spheres, indicating that the sphere cells had commenced differentiation to the germ lineage. However, the spheres did not proceed to spermatogenesis after transplantation into testes. Sphere cell transfer to the original feeder-free ESC cultures resulted in chaotic differentiation. In contrast, when the spheres were cultured on mouse embryonic fibroblasts or in the presence of ERK-cascade and GSK3 inhibitors, reversion to the ESC-like state was observed. These results indicate that Akt signaling promotes a novel metastable and pluripotent state that is intermediate to those of ESCs and PGCs.

  20. Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures

    SciTech Connect (OSTI)

    Dartel, Dorien A.M. van; Pennings, Jeroen L.A.; Fonteyne, Liset J.J. de la; Brauers, Karen J.J.; Claessen, Sandra; Delft, Joost H. van; Kleinjans, Jos C.S.; Piersma, Aldert H.

    2011-03-01

    The murine embryonic stem cell test (EST) is designed to evaluate developmental toxicity based on compound-induced inhibition of embryonic stem cell (ESC) differentiation into cardiomyocytes. The addition of transcriptomic evaluation within the EST may result in enhanced predictability and improved characterization of the applicability domain, therefore improving usage of the EST for regulatory testing strategies. Transcriptomic analyses assessing factors critical for risk assessment (i.e. dose) are needed to determine the value of transcriptomic evaluation in the EST. Here, using the developmentally toxic compound, flusilazole, we investigated the effect of compound concentration on gene expression regulation and toxicity prediction in ESC differentiation cultures. Cultures were exposed for 24 h to multiple concentrations of flusilazole (0.54-54 {mu}M) and RNA was isolated. In addition, we sampled control cultures 0, 24, and 48 h to evaluate the transcriptomic status of the cultures across differentiation. Transcriptomic profiling identified a higher sensitivity of development-related processes as compared to cell division-related processes in flusilazole-exposed differentiation cultures. Furthermore, the sterol synthesis-related mode of action of flusilazole toxicity was detected. Principal component analysis using gene sets related to normal ESC differentiation was used to describe the dynamics of ESC differentiation, defined as the 'differentiation track'. The concentration-dependent effects on development were reflected in the significance of deviation of flusilazole-exposed cultures from this transcriptomic-based differentiation track. Thus, the detection of developmental toxicity in EST using transcriptomics was shown to be compound concentration-dependent. This study provides further insight into the possible application of transcriptomics in the EST as an improved alternative model system for developmental toxicity testing.