National Library of Energy BETA

Sample records for auto repair shop

  1. Exposure Evaluation for Benzene, Lead and Noise in Vehicle and Equipment Repair Shops

    SciTech Connect (OSTI)

    Sweeney, Lynn C.

    2013-04-10

    An exposure assessment was performed at the equipment and vehicle maintenance repair shops operating at the U. S. Department of Energy Hanford site, in Richland, Washington. The maintenance shops repair and maintain vehicles and equipment used in support of the Hanford cleanup mission. There are three general mechanic shops and one auto body repair shop. The mechanics work on heavy equipment used in construction, cranes, commercial motor vehicles, passenger-type vehicles in addition to air compressors, generators, and farm equipment. Services include part fabrication, installation of equipment, repair and maintenance work in the engine compartment, and tire and brake services. Work performed at the auto body shop includes painting and surface preparation which involves applying body filler and sanding. 8-hour time-weighted-average samples were collected for benzene and noise exposure and task-based samples were collected for lead dust work activities involving painted metal surfaces. Benzene samples were obtained using 3M™ 3520 sampling badges and were analyzed for additional volatile organic compounds. These compounds were selected based on material safety data sheet information for the aerosol products used by the mechanics for each day of sampling. The compounds included acetone, ethyl ether, toluene, xylene, VM&P naphtha, methyl ethyl ketone, and trichloroethylene. Laboratory data for benzene, VM&P naphtha, methyl ethyl ketone and trichloroethylene were all below the reporting detection limit. Airborne concentrations for acetone, ethyl ether, toluene and xylene were all less than 10% of their occupational exposure limit. The task-based samples obtained for lead dusts were submitted for a metal scan analysis to identify other metals that might be present. Laboratory results for lead dusts were all below the reporting detection limit and airborne concentration for the other metals observed in the samples were less than 10% of the occupational exposure limit. Noise dosimetry sampling was performed on a random basis and was representative of the different work activities within the four shops. Twenty three percent of the noise samples exceeded the occupational exposure limit of 85 decibels for an 8-hour time-weightedaverage. Work activities where noise levels were higher included use of impact wrenches and grinding wheels.

  2. Waste minimization in an autobody repair shop

    SciTech Connect (OSTI)

    Baria, D.N.; Dorland, D.; Bergeron, J.T.

    1994-12-31

    This work was done to document the waste minimization incorporated in a new autobody repair facility in Hermantown, Minnesota. Humes Collision Center incorporated new waste reduction techniques when it expanded its old facilities in 1992 and it was able to achieve the benefits of cost reduction and waste reduction. Humes Collision Center repairs an average of 500 cars annually and is a very small quantity generator (VSQG) of hazardous waste, as defined by the Minnesota Pollution Control Agency (MPCA). The hazardous waste consists of antifreeze, batteries, paint sludge, refrigerants, and used oil, while the nonhazardous waste consists of cardboard, glass, paint filters, plastic, sanding dust, scrap metal, and wastewater. The hazardous and nonhazardous waste output were decreased by 72%. In addition, there was a 63% reduction in the operating costs. The waste minimization includes antifreeze recovery and recycling, reduction in unused waste paint, reduction, recovery and recycle of waste lacquer thinner for cleaning spray guns and paint cups, elimination of used plastic car bags, recovery and recycle of refrigerant, reduction in waste sandpaper and elimination of sanding dust, and elimination of waste paint filters. The rate of return on the investment in waste minimization equipment is estimated from 37% per year for the distillation unit, 80% for vacuum sanding, 146% for computerized paint mixing, 211% for the refrigerant recycler, to 588% per year for the gun washer. The corresponding payback time varies from 3 years to 2 months.

  3. Shop Request - 88-Inch Cyclotron

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Shop Request Note: You must be logged in to your Berkeley Lab LDAP account to access the Shop Request Form. 88 Work Request Shop Request ‎(Responses)‎ Open Spreadsheet

  4. Byers Auto | Open Energy Information

    Open Energy Info (EERE)

    Facility Byers Auto Sector Wind energy Facility Type Small Scale Wind Facility Status In Service Owner Byers Auto Energy Purchaser Byers Auto Location Columbus OH Coordinates...

  5. Development Shop | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Development Shop The Ames Laboratory operates a complete machine shop. Our shop consists of the modern equipment needed to fabricate almost any conceivable device required for research project. If you have a need or any questions about the fabrication of items to support your mission in research please contact us. Our machining equipment includes: Lathes CNC Bridgeport Mills Shears Press Brake (for bending) EDM (Electronic Discharge Machining) Grinders Saws We are capable of welding nearly any

  6. Solar Shop Australia | Open Energy Information

    Open Energy Info (EERE)

    Shop Australia Jump to: navigation, search Name: Solar Shop Australia Place: Adelaide, South Australia, Australia Zip: SA 5069 Sector: Renewable Energy Product: South...

  7. Process Waste Assessment - Paint Shop

    SciTech Connect (OSTI)

    Phillips, N.M.

    1993-06-01

    This Process Waste Assessment was conducted to evaluate hazardous wastes generated in the Paint Shop, Building 913, Room 130. Special attention is given to waste streams generated by the spray painting process because it requires a number of steps for preparing, priming, and painting an object. Also, the spray paint booth covers the largest area in R-130. The largest and most costly waste stream to dispose of is {open_quote}Paint Shop waste{close_quotes} -- a combination of paint cans, rags, sticks, filters, and paper containers. These items are compacted in 55-gallon drums and disposed of as solid hazardous waste. Recommendations are made for minimizing waste in the Paint Shop. Paint Shop personnel are very aware of the need to minimize hazardous wastes and are continuously looking for opportunities to do so.

  8. PERI auto-tuning.

    SciTech Connect (OSTI)

    Chame, J.; Chen, C.; Dongarra, J.; Hall, M.; Hollingsworth, J. K.; Hovland, P.; Moore, S.; Seymour, K.; Shin, J.; Tiwari, A.; Williams, S.; You, H.; Bailey, D. H.

    2008-01-01

    The enormous and growing complexity of today's high-end systems has increased the already significant challenges of obtaining high performance on equally complex scientific applications. Application scientists are faced with a daunting challenge in tuning their codes to exploit performance-enhancing architectural features. The Performance Engineering Research Institute (PERI) is working toward the goal of automating portions of the performance tuning process. This paper describes PERI's overall strategy for auto-tuning tools and recent progress in both building auto-tuning tools and demonstrating their success on kernels, some taken from large-scale applications.

  9. AutoMOD

    Energy Science and Technology Software Center (OSTI)

    2006-10-23

    AutoMOD provides a framework for automatic analysis and comparison of results from ocean model simulations with observational data products and other model simulations. Automated analysis includes comparison to model simulations fromthe Eurpoean Ocean Carbon-Cycle Model Intecomparison Project (EurOCMIp).

  10. Rebuilding the American Auto Industry

    Broader source: Energy.gov [DOE]

    The Administration made strategic investments to help U.S. auto manufacturers retool to produce the hybrid, electric, and highly fuel efficient advanced vehicles of the future. With the help of these investments -- and the incredible talent and commitment of America's auto workers -- the auto industry is growing again.

  11. Electronic Fabrication & Repair | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Electronic Fabrication & Repair The Electronics group provides custom design and fabrication of electronic equipment.. We convert ideas into custom-finished equipment in our shop using ORCAD Schematic Capture and PCB Layout software in conjunction with our PCB machine to make prototype circuit boards in-house. Our technicians also aid in automating and controlling research project instrumentation using Texas Instruments LabView. We repair all kinds of scientific and laboratory electronic and

  12. Detroit Auto Show 2012 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Detroit Auto Show 2012 Detroit Auto Show 2012 Addthis 1 of 10 Energy Secretary Steven Chu with Chrysler Chief Executive Sergio Marchionne. Image: Hantz Leger (Energy Department ...

  13. FormCampusMachineShopsLabs.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Highway Baton Rouge, Louisiana 70806 225-578-8887 225-578-6954 (Fax) Form for Campus Machine Shops and Labs Purchaser's Name Phone ...

  14. Tips: Shopping for Appliances | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Appliances Tips: Shopping for Appliances What's the real cost? Every appliance has two price tags -- the purchase price and the operating cost. Consider both when buying a new...

  15. AutoPIPE Extract Program

    Energy Science and Technology Software Center (OSTI)

    1993-07-02

    The AutoPIPE Extract Program (APEX) provides an interface between CADAM (Computer Aided Design and Manufacturing) Release 21 drafting software and the AutoPIPE, Version 4.4, piping analysis program. APEX produces the AutoPIPE batch input file that corresponds to the piping shown in a CADAM model. The card image file contains header cards, material cards, and pipe cross section cards as well as tee, bend, valve, and flange cards. Node numbers are automatically generated. APEX processes straightmore » pipe, branch lines and ring geometries.« less

  16. Klamath County Shops Space Heating Low Temperature Geothermal...

    Open Energy Info (EERE)

    Shops Space Heating Low Temperature Geothermal Facility Jump to: navigation, search Name Klamath County Shops Space Heating Low Temperature Geothermal Facility Facility Klamath...

  17. Tips: Shopping for Appliances | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Shopping for Appliances Tips: Shopping for Appliances What's the real cost? Every appliance has two price tags -- the purchase price and the operating cost. Consider both when buying a new appliance. What's the real cost? Every appliance has two price tags -- the purchase price and the operating cost. Consider both when buying a new appliance. When you're shopping for appliances, think of two price tags. The first one covers the purchase price -- think of it as a down payment. The second price

  18. CRAD, Machine Shop Safe Operations Assessment Plan

    Broader source: Energy.gov [DOE]

    The purpose of this assessment is to verify that machine shop operators are provided a safe and healthful workplace which will reduce or prevent injuries, illnesses, and accidental losses.

  19. Property:Building/FloorAreaShops | Open Energy Information

    Open Energy Info (EERE)

    Property Edit with form History Property:BuildingFloorAreaShops Jump to: navigation, search This is a property of type Number. Floor area for Shops Pages using the property...

  20. Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades...

    Office of Environmental Management (EM)

    Your One Stop Shop for Energy Efficiency Upgrades Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades This is a presentation from Energy Impact Illinois posted on the...

  1. Turbine repair process, repaired coating, and repaired turbine component

    DOE Patents [OSTI]

    Das, Rupak; Delvaux, John McConnell; Garcia-Crespo, Andres Jose

    2015-11-03

    A turbine repair process, a repaired coating, and a repaired turbine component are disclosed. The turbine repair process includes providing a turbine component having a higher-pressure region and a lower-pressure region, introducing particles into the higher-pressure region, and at least partially repairing an opening between the higher-pressure region and the lower-pressure region with at least one of the particles to form a repaired turbine component. The repaired coating includes a silicon material, a ceramic matrix composite material, and a repaired region having the silicon material deposited on and surrounded by the ceramic matrix composite material. The repaired turbine component a ceramic matrix composite layer and a repaired region having silicon material deposited on and surrounded by the ceramic matrix composite material.

  2. Secretary Chu Tours the 2013 Washington Auto Show | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Tours the 2013 Washington Auto Show Secretary Chu Tours the 2013 Washington Auto Show January 31, 2013 - 5:04pm Addthis 1 of 10 While at the Washington Auto Show, Energy Secretary ...

  3. Materials, Modules, and Systems: An Atoms to Autos Approach to...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Materials, Modules, and Systems: An Atoms to Autos Approach to Automotive Thermoelectric Systems Development Materials, Modules, and Systems: An Atoms to Autos Approach to ...

  4. Auto/Steel Partnership: Fatigue of AHSS Strain Rate Characterization...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fatigue of AHSS Strain Rate Characterization AutoSteel Partnership: Fatigue of AHSS ... More Documents & Publications AutoSteel Partnership: AHSS Stamping, Strain Rate ...

  5. Shanghai Jieneng Auto Technology Co Ltd | Open Energy Information

    Open Energy Info (EERE)

    Auto Technology Co Ltd Place: Shanghai Municipality, China Product: Shanghai-based electric car technology company. References: Shanghai Jieneng Auto Technology Co Ltd1...

  6. Auto/Steel Partnership: AHSS Stamping, Strain Rate Characterization...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AHSS Stamping, Strain Rate Characterization, Sheet Steel Fatigue, AHSS Joining AutoSteel ... More Documents & Publications AutoSteel Partnership: Fatigue of AHSS Strain Rate ...

  7. January 2014 Cybersecurity Awareness Campaign - Secure Online Shopping |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy 4 Cybersecurity Awareness Campaign - Secure Online Shopping January 2014 Cybersecurity Awareness Campaign - Secure Online Shopping The January 2014 Cybersecurity Awareness Campaign featured issues surrounding secure online shopping. For more information on privacy issues, contact Jerry Hanley at Jerry.Hanley@hq.doe.gov. For information on Supply Chain Risk Management, contact Sue Farrand at Susan.Farrand@hq.doe.gov. PDF icon Cybersecurity Front Burner Issue 15 PDF icon

  8. Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Your One Stop Shop for Energy Efficiency Upgrades Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades This is a presentation from Energy Impact Illinois posted on the website of the U.S. Department of Energy's Better Buildings Neighborhood Program. PDF icon Energy Savers from CNT Energy More Documents & Publications Energy Savers: A one-stop energy efficiency shop for multifamily building owners Energy Savers: Fireplaces

  9. Savannah River Site - Central Shops GW OU | Department of Energy

    Office of Environmental Management (EM)

    Central Shops GW OU Savannah River Site - Central Shops GW OU January 1, 2013 - 12:00pm Addthis US Department of Energy Groundwater Database Groundwater Master Report InstallationName, State: Savannah River Site, SC Responsible DOE Office: Savannah River Site Plume Name: Central Shops GW OU Remediation Contractor: Savannah River Nuclear Solutions, LLC PBS Number: 30 Report Last Updated: 2013 Contaminants Halogenated VOCs/SVOCs Present?: Yes VOC Name Concentration (ppb) Regulatory Driver Cleanup

  10. 2016 Washington Auto Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Washington Auto Show 2016 Washington Auto Show Addthis 1 of 20 Energy Secretary Ernest Moniz sits in the driver's seat of the all-electric Chevrolet Bolt at the Washington Auto Show. When it debuts on the road later this year, the Bolt will offer drivers about 200 miles of electric range. Image: Simon Edelman, Energy Department Date taken: 2016-01-21 09:45 2 of 20 The 2016 next-generation Chevrolet Volt builds on the success of its previous version, which was the first plug-in hybrid electric

  11. 2013 Washington Auto Show | Department of Energy

    Energy Savers [EERE]

    Washington Auto Show 2013 Washington Auto Show Addthis 1 of 10 While at the Washington Auto Show, Energy Secretary Steven Chu visited Nissan to see the 2013 Leaf. | Photo courtesy of Sarah Gerrity, Energy Department. Date taken: 2013-01-31 13:50 2 of 10 The new Nissan Leaf is being built at the company's Smyrna, Tennessee, Vehicle Assembly Plant -- helping to cut the price of its electric vehicle. | Photo courtesy of Sarah Gerrity, Energy Department. Date taken: 2013-01-31 13:49 3 of 10 Energy

  12. APEX. AutoPIPE Extract Program

    SciTech Connect (OSTI)

    Cline, B.E.

    1992-07-01

    The AutoPIPE Extract Program (APEX) provides an interface between CADAM (Computer Aided Design and Manufacturing) Release 21 drafting software and the AutoPIPE, Version 4.4, piping analysis program. APEX produces the AutoPIPE batch input file that corresponds to the piping shown in a CADAM model. The card image file contains header cards, material cards, and pipe cross section cards as well as tee, bend, valve, and flange cards. Node numbers are automatically generated. APEX processes straight pipe, branch lines and ring geometries.

  13. The Resurgence of America's Auto Industry

    ScienceCinema (OSTI)

    Zimmer, Stephen; Cischke, Sue;

    2013-05-29

    A look at how strategic investments and partnerships between the Energy Department and automakers have helped the American auto industry become a leader in advanced and fuel-efficient vehicles ? creating jobs and boosting profits in the process.

  14. 2015 Washington Auto Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Washington Auto Show 2015 Washington Auto Show Addthis Moniz Delivers Keynote Remarks 1 of 10 Moniz Delivers Keynote Remarks Secretary Moniz touted the Department's investments in advanced vehicle technologies, infrastructure and manufacturing. Photo by Sarah Gerrity Date taken: 2015-01-22 04:33 Secretary Moniz Announces More than $55M in Fuel-Efficient Vehicle Funding 2 of 10 Secretary Moniz Announces More than $55M in Fuel-Efficient Vehicle Funding The funding opportunities will go towards a

  15. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Nancy Porter; Mike Sullivan; Chris Neary

    2003-05-01

    The two broad categories of deposited weld metal repair and fiber-reinforced composite repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repairs and for fiber-reinforced composite repair. To date, all of the experimental work pertaining to the evaluation of potential repair methods has focused on fiber-reinforced composite repairs. Hydrostatic testing was also conducted on four pipeline sections with simulated corrosion damage: two with composite liners and two without.

  16. Waste audit study: Automotive paint shops

    SciTech Connect (OSTI)

    Not Available

    1987-01-01

    This report presents the results of a waste-audit study of automotive paint shops. The study focuses on the types and quantities of wastes generated, treatment and disposal alternatives, and the potential for reducing the amount and/or toxicity of waste generated. The analysis of solvent waste minimization focused primarily on in-plant modifications (e.g., source reduction) to reduce the generation of solvent waste. Strict inventory control is the most-readily implementable approach. While in-house recycling is viable, it is usually only cost-effective for larger firms. Specific recommendations for waste reduction were made.

  17. New Online Tool Creates One-Stop Shop for Federal Program Opportunitie...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Online Tool Creates One-Stop Shop for Federal Program Opportunities That Support Tribal Energy Development New Online Tool Creates One-Stop Shop for Federal Program Opportunities ...

  18. From Shop Floor to Top Floor: Best Business Practices in Energy...

    Open Energy Info (EERE)

    Shop Floor to Top Floor: Best Business Practices in Energy Efficiency Jump to: navigation, search Tool Summary LAUNCH TOOL Name: From Shop Floor to Top Floor: Best Business...

  19. Argonne/EPA system captures mercury from air in gold shops |...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Typical gold shop hood used to purify gold by superheating the goldmercury amalgam until the mercury vaporizes. The vaporized mercury is directed outside the shop into the open...

  20. Parallel auto-correlative statistics with VTK.

    SciTech Connect (OSTI)

    Pebay, Philippe Pierre; Bennett, Janine Camille

    2013-08-01

    This report summarizes existing statistical engines in VTK and presents both the serial and parallel auto-correlative statistics engines. It is a sequel to [PT08, BPRT09b, PT09, BPT09, PT10] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, contingency, k-means, and order statistics engines. The ease of use of the new parallel auto-correlative statistics engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the autocorrelative statistics engine.

  1. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, L.M.

    1998-05-05

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find at the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was not heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past. 2 figs.

  2. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, Leo M.

    1998-01-01

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find an the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was was heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past.

  3. EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles April 18, 2013 - 12:00am Addthis The ...

  4. Fact #828: July 7, 2014 Japanese Auto Manufacturers Increase...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8: July 7, 2014 Japanese Auto Manufacturers Increase Domestic Production for U.S. Sales Fact 828: July 7, 2014 Japanese Auto Manufacturers Increase Domestic Production for U.S. ...

  5. Fisker, Tesla, and American Auto Innovation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fisker, Tesla, and American Auto Innovation Fisker, Tesla, and American Auto Innovation October 20, 2011 - 10:36pm Addthis Dan Leistikow Dan Leistikow Former Director, Office of Public Affairs Two years ago, critics said we shouldn't be investing in American auto manufacturing because the industry wouldn't survive. They were wrong then and they're wrong today. From well established names like Ford to innovative startups like Tesla and Fisker, America's auto industry is being reinvented, and the

  6. ProteinShop: A tool for interactive protein manipulation and...

    Office of Scientific and Technical Information (OSTI)

    ProteinShop may be used at different stages of a protein structure prediction process. ... Last, it serves as a visual framework to monitor and steer a protein structure prediction ...

  7. PERI Auto-tuning Memory Intensive Kernels

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    PERI - Auto-tuning Memory Intensive Kernels for Multicore Samuel Williams † , Kaushik Datta † , Jonathan Carter , Leonid Oliker † , John Shalf , Katherine Yelick † , David Bailey CRD/NERSC, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA † Computer Science Division, University of California at Berkeley, Berkeley, CA 94720, USA E-mail: SWWilliams@lbl.gov, kdatta@eecs.berkeley.edu, JTCarter@lbl.gov, LOliker@lbl.gov, JShalf@lbl.gov, KAYelick@lbl.gov, DHBailey@lbl.gov

  8. VEE-0084- In the Matter of Gas’n Shop, Inc.

    Office of Energy Efficiency and Renewable Energy (EERE)

    On March 26, 2002, Gas’n Shop, Inc. (Gas’n Shop) of Lincoln, Nebraska filed an Application for Exception with the Office of Hearings and Appeals (OHA) of the Department of Energy (DOE). In its...

  9. Energy Savers: A one-stop energy efficiency shop for multifamily...

    Office of Environmental Management (EM)

    A one-stop energy efficiency shop for multifamily building owners Energy Savers: A one-stop energy efficiency shop for multifamily building owners This is a document from Energy...

  10. Green your Back to School Shopping List! | Department of Energy

    Energy Savers [EERE]

    your Back to School Shopping List! Green your Back to School Shopping List! August 23, 2013 - 10:06am Addthis Save energy and money while buying school supplies this year. | Photo courtesy of ©iStockphoto/Ls9907 Save energy and money while buying school supplies this year. | Photo courtesy of ©iStockphoto/Ls9907 Agatha Wein Communications Specialist, State Energy Program How can I participate? You can save energy and money this fall by simply reducing, reusing, and recycling school supplies.

  11. ProteinShop: A tool for interactive protein manipulation and steering

    Office of Scientific and Technical Information (OSTI)

    (Journal Article) | SciTech Connect ProteinShop: A tool for interactive protein manipulation and steering Citation Details In-Document Search Title: ProteinShop: A tool for interactive protein manipulation and steering We describe ProteinShop, a new visualization tool that streamlines and simplifies the process of determining optimal protein folds. ProteinShop may be used at different stages of a protein structure prediction process. First, it can create protein configurations containing

  12. EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles

    Broader source: Energy.gov [DOE]

    Auto manufacturers demonstrate that switching from a gasoline to a hydrogen fuel cell engine could reduce emissions by more than 90%.

  13. Auto/Steel Partnership: Hydroforming Materials and Lubricant...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AutoSteel Partnership: Hydroforming Materials and Lubricant Lightweight Rear Chassis ... FY 2008 Progress Report for Lightweighting Materials - 5. Automotive Metals-Steel FY 2009 ...

  14. Auto/Steel Partnership: Advanced High-Strength Steel Research...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Advanced High-Strength Steel Research and Development AutoSteel Partnership: Advanced High-Strength Steel Research and Development 2009 DOE Hydrogen Program and Vehicle ...

  15. Global Fuel Economy Initiative Auto Fuel Efficiency ToolSet ...

    Open Energy Info (EERE)

    Efficiency ToolSet Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Global Fuel Economy Initiative Auto Fuel Efficiency ToolSet AgencyCompany Organization: FIA...

  16. EERE Success Story-EERE and Auto Manufacturers Demonstrate and...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addthis The National Fuel Cell Electric Vehicle Learning Demonstration-funded and managed ... Four teams took part in the Learning Demonstration, in which auto manufacturers Ford Motor ...

  17. Secretary Moniz to Deliver Keynote at Washington Auto Show

    Broader source: Energy.gov [DOE]

    On Wednesday, January 22, 2014, Energy Secretary Ernest Moniz will deliver the government keynote address at the Washington Auto Show’s Public Policy Day.

  18. SLIDESHOW: Secretary Moniz Tours 2014 Washington Auto Show

    Broader source: Energy.gov [DOE]

    A slideshow featuring highlights from Secretary Moniz's tour of the 2014 Washington Auto Show is currently posted on the Energy Department's blog.

  19. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Bill Bruce; Nancy Porter; George Ritter; Matt Boring; Mark Lozev; Ian Harris; Bill Mohr; Dennis Harwig; Robin Gordon; Chris Neary; Mike Sullivan

    2005-07-20

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. In lieu of a field installation on an abandoned pipeline, a preliminary nondestructive testing protocol is being developed to determine the success or failure of the fiber-reinforced liner pipeline repairs. Optimization and validation activities for carbon-fiber repair methods are ongoing.

  20. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-12-31

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. The first round of optimization and validation activities for carbon-fiber repairs are complete. Development of a comprehensive test plan for this process is recommended for use in the field trial portion of this program.

  1. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-08-17

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the field trial portion of this program.

  2. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, Leo M.

    1999-01-01

    Disclosed are improvments to a rapid road repair vehicle comprising an improved cleaning device arrangement, two dispensing arrays for filling defects more rapidly and efficiently, an array of pre-heaters to heat the road way surface in order to help the repair material better bond to the repaired surface, a means for detecting, measuring, and computing the number, location and volume of each of the detected surface imperfection, and a computer means schema for controlling the operation of the plurality of vehicle subsystems. The improved vehicle is, therefore, better able to perform its intended function of filling surface imperfections while moving over those surfaces at near normal traffic speeds.

  3. Service and Repair Work

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Service and Repair Work Whenever on-site service or repair work needs to be done, a Procurement Work Sheet (PWS) must be completed, and possibly an IWS, authorized and released. PWS is required for service work even if there are no apparent hazards. PWS is required for work in Jupiter Laser Facility even if you have a PWS for service/repairs in another location. To complete a PWS for service work in Jupiter Laser Facility, please contact Sean Holte (2-3905, pager #05312). Notify Brent Stuart and

  4. Performance Optimization and Auto-Tuning

    SciTech Connect (OSTI)

    Howison, Mark

    2012-10-01

    In the broader computational research community, one subject of recent research is the problem of adapting algorithms to make effective use of multi- and many-core processors. Effective use of these architectures, which have complex memory hierarchies with many layers of cache, typically involves a careful examination of how an algorithm moves data through the memory hierarchy. Unfortunately, there is often a non-obvious relationship between algorithmic parameters like blocking strategies, and their impact on memory utilization, and, in turn, the relationship with runtime performance. Auto-tuning is an empirical method used to discover optimal values for tunable algorithmic parameters under such circumstances. The challenge is compounded by the fact that the settings that produce the best performance for a given problem and a given platform may not be the best for a different problem on the same platform, or the same problem on a different platform. The high performance visualization research community has begun to explore and adapt the principles of auto-tuning for the purpose of optimizing codes on modern multi- and many-core processors. This report focuses on how performance optimization studies reveal a dramatic variation in performance for two fundamental visualization algorithms: one based on a stencil operation having structured, uniform memory access, and the other is ray casting volume rendering, which uses unstructured memory access patterns. The two case studies highlighted in this report show the extra effort required to optimize such codes by adjusting the tunable algorithmic parameters can return substantial gains in performance. Additionally, these case studies also explore the potential impact of and the interaction between algorithmic optimizations and tunable algorithmic parameters, along with the potential performance gains resulting from leveraging architecture-specific features.

  5. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; Nancy Porter; Mike Sullivan; Chris Neary

    2004-04-12

    The two broad categories of deposited weld metal repair and fiber-reinforced composite liner repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repair and for fiber-reinforced composite liner repair. Evaluation trials have been conducted using a modified fiber-reinforced composite liner provided by RolaTube and pipe sections without liners. All pipe section specimens failed in areas of simulated damage. Pipe sections containing fiber-reinforced composite liners failed at pressures marginally greater than the pipe sections without liners. The next step is to evaluate a liner material with a modulus of elasticity approximately 95% of the modulus of elasticity for steel. Preliminary welding parameters were developed for deposited weld metal repair in preparation of the receipt of Pacific Gas & Electric's internal pipeline welding repair system (that was designed specifically for 559 mm (22 in.) diameter pipe) and the receipt of 559 mm (22 in.) pipe sections from Panhandle Eastern. The next steps are to transfer welding parameters to the PG&E system and to pressure test repaired pipe sections to failure. A survey of pipeline operators was conducted to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. Completed surveys contained the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) Pipe diameter sizes range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.). The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.), with 95% using 558.8 mm (22 in.) pipe. An evaluation of potential repair methods clearly indicates that the project should continue to focus on the development of a repair process involving the use of GMAW welding and on the development of a repair process involving the use of fiber-reinforced composite liners.

  6. Holiday Shopping and Electric Vehicles | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Holiday Gifts for Energy Efficiency Holiday Gifts for Energy Efficiency December 18, 2013 - 3:58pm Addthis Energy-efficient light bulbs can make great energy-saving stocking stuffers. Energy-efficient light bulbs can make great energy-saving stocking stuffers. Erik Hyrkas Erik Hyrkas Media Relations Specialist, Office of Energy Efficiency & Renewable Energy How can I participate? Look for these energy-saving gifts while doing your holiday shopping this year. As the days get colder and

  7. Secretary Chu Speaks at the 2010 Washington Auto Show

    Broader source: Energy.gov [DOE]

    at the 2010 Washington Auto Show, Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need. He also announced that the Department of Energy had...

  8. Energy Secretary Moniz at the 2016 Washington Auto Show | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    With sales reaching an all-time high last year and more than half a million new jobs created since 2009, the auto industry is roaring back to life. Watch this video of Energy ...

  9. Polarization imaging apparatus with auto-calibration

    DOE Patents [OSTI]

    Zou, Yingyin Kevin; Zhao, Hongzhi; Chen, Qiushui

    2013-08-20

    A polarization imaging apparatus measures the Stokes image of a sample. The apparatus consists of an optical lens set, a first variable phase retarder (VPR) with its optical axis aligned 22.5.degree., a second variable phase retarder with its optical axis aligned 45.degree., a linear polarizer, a imaging sensor for sensing the intensity images of the sample, a controller and a computer. Two variable phase retarders were controlled independently by a computer through a controller unit which generates a sequential of voltages to control the phase retardations of the first and second variable phase retarders. A auto-calibration procedure was incorporated into the polarization imaging apparatus to correct the misalignment of first and second VPRs, as well as the half-wave voltage of the VPRs. A set of four intensity images, I.sub.0, I.sub.1, I.sub.2 and I.sub.3 of the sample were captured by imaging sensor when the phase retardations of VPRs were set at (0,0), (.pi.,0), (.pi.,.pi.) and (.pi./2,.pi.), respectively. Then four Stokes components of a Stokes image, S.sub.0, S.sub.1, S.sub.2 and S.sub.3 were calculated using the four intensity images.

  10. Washington Auto Show Spotlight: How Fuel Cell Electric Vehicles Work |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Washington Auto Show Spotlight: How Fuel Cell Electric Vehicles Work Washington Auto Show Spotlight: How Fuel Cell Electric Vehicles Work January 27, 2015 - 12:57pm Addthis The Hyundai Tucson FCEV is currently available for lease in Southern California for less than $500 per month, including free hydrogen fuel. Hydrogen for FCEVs can be produced from a variety of resources all providing emission reductions. Hydrogen derived from natural gas reduces emissions by half and

  11. Obama Administration Awards First Three Auto Loans for Advanced

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technologies to Ford Motor Company, Nissan Motors and Tesla Motors | Department of Energy First Three Auto Loans for Advanced Technologies to Ford Motor Company, Nissan Motors and Tesla Motors Obama Administration Awards First Three Auto Loans for Advanced Technologies to Ford Motor Company, Nissan Motors and Tesla Motors June 23, 2009 - 12:00am Addthis Washington, DC -- Today, the Obama Administration announced $8 billion in conditional loan commitments for the development of innovative,

  12. Automatic Performance Collection (AutoPerf) | Argonne Leadership Computing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Facility Automatic Performance Collection (AutoPerf) A library for the automatic collection of hardware performance counter and MPI information is available on ALCF BG/Q machines (Mira, Cetus, Vesta). This library transparently collects performance data from running jobs and saves it into files at jobs completion. AutoPerf is enabled by default on Cetus, Mira, and Vesta - no action will be needed to utilize the library. Executables complied or linked on on these machine will automatically be

  13. Amber Plug-In for Protein Shop () | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Software: Amber Plug-In for Protein Shop Citation Details Software Request Title: Amber Plug-In for Protein Shop The Amber Plug-in for ProteinShop has two main components: an AmberEngine library to compute the protein energy models, and a module to solve the energy minimization problem using an optimization algorithm in the OPTI-+ library. Together, these components allow the visualization of the protein folding process in ProteinShop. AmberEngine is a object-oriented library to compute

  14. Auto Indexer Auto-Indexer for Percussive Hammers: Vane Motor Dynamometer Testing

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Su, Jiann

    The development of the motor will help to achieve program technical objectives by improving well construction capabilities. This includes enabling high-temperature drilling as well as enhancing directional drilling. A key component in the auto indexer is the drive motor. It is an air-driven vane motor that converts the energy stored in the compressed air to mechanical energy. The motor is attached to hammer-like components which impart an impulsive load onto the drive shaft. The impulsive force on the drive shaft in turn creates an indexing action. A controlled test was performed to characterize the performance of the the vane motor for a given pressure. The Sandia dynamometer test station was used to determine the performance of the motor for a given input pressure.

  15. Auto Indexer Auto-Indexer for Percussive Hammers: Vane Motor Dynamometer Testing

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Su, Jiann

    2012-01-01

    The development of the motor will help to achieve program technical objectives by improving well construction capabilities. This includes enabling high-temperature drilling as well as enhancing directional drilling. A key component in the auto indexer is the drive motor. It is an air-driven vane motor that converts the energy stored in the compressed air to mechanical energy. The motor is attached to hammer-like components which impart an impulsive load onto the drive shaft. The impulsive force on the drive shaft in turn creates an indexing action. A controlled test was performed to characterize the performance of the the vane motor for a given pressure. The Sandia dynamometer test station was used to determine the performance of the motor for a given input pressure.

  16. 2014 Washington Auto Show Slideshow | Department of Energy

    Energy Savers [EERE]

    4 Washington Auto Show Slideshow 2014 Washington Auto Show Slideshow Addthis Hyundai Fuel Cell 1 of 14 Hyundai Fuel Cell Pictured here is Secretary Moniz looking at the fuel cell and motor used to power Hyundai's Tucson fuel cell vehicle. Fuel cell vehicles use hydrogen to produce electricity, which powers an electric motor to make the vehicle and its accessories work. Image: Sarah Gerrity, Energy Department. Date taken: 2014-01-22 11:14 Under the hood of the Hyundai Tucson Fuel Cell Vehicle 2

  17. Ping-pong auto-zero amplifier with glitch reduction

    DOE Patents [OSTI]

    Larson, Mark R.

    2008-01-22

    A ping-pong amplifier with reduced glitching is described. The ping-pong amplifier includes a nulling amplifier coupled to a switching network. The switching network is used to auto-zero a ping amplifier within a ping-pong amplifier. The nulling amplifier drives the output of a ping amplifier to a proper output voltage level during auto-zeroing of the ping amplifier. By being at a proper output voltage level, glitches associated with transitioning between a ping amplifier and a pong amplifier are reduced or eliminated.

  18. TAN Hot Shop and Support Facility Utilization Study

    SciTech Connect (OSTI)

    Picker, B.A.

    2001-11-16

    Impacts to the U.S. Department of Energy (DOE) complex caused by early closure (prior to 2018) and Demolition and Dismantlement (D and D) of the Test Area North (TAN) hot shop and its support facilities are explored in this report. Various possible conditions, such as Standby, Safe Store and Lay-up, that the facility may be placed in prior to eventually being turned over to D and D are addressed. The requirements, impacts, and implications to the facility and to the DOE Complex are discussed for each condition presented in the report. Some details of the report reference the Idaho National Engineering and Environmental Laboratory (INEEL) Spent Nuclear Fuel Life Cycle Baseline Plan, the INEEL 2000 Infrastructure Long Range Plan, and other internal INEEL reports.

  19. TAN HOT SHOP AND SUPPORT FACILITY UTILIZATION STUDY

    SciTech Connect (OSTI)

    Phillips, Ken Crawforth

    2001-11-01

    Impacts to the U.S. Department of Energy (DOE) complex caused by early closure (prior to 2018) and Demolition and Dismantlement (D&D) of the Test Area North (TAN) hot shop and its support facilities are explored in this report. Various possible conditions, such as Standby, Safe Store and Lay-up, that the facility may be placed in prior to eventually being turned over to D&D are addressed. The requirements, impacts, and implications to the facility and to the DOE Complex are discussed for each condition presented in the report. Some details of the report reference the Idaho National Engineering and Environmental Laboratory (INEEL) Spent Nuclear Fuel Life Cycle Baseline Plan, the INEEL 2000 Infrastructure Long Range Plan, and other internal INEEL reports.

  20. Chongqing ChangAn New Energy Auto Co Ltd | Open Energy Information

    Open Energy Info (EERE)

    Auto Co Ltd Place: Chongqing Municipality, China Product: Chongqing-headquartered hybrid car maker. References: Chongqing ChangAn New Energy Auto Co Ltd1 This article is a stub....

  1. AutoGrid - Turning Big Data Into Power with the Energy Data Platform and Apps

    SciTech Connect (OSTI)

    Narayan, Amit; Dresselhuys, Eric; Kulp, Yann; Buseman, Greg; Piette, Mary Ann; Tang, Andrew; Dailey, Karla; Knudsen, Chris

    2014-03-25

    AutoGrid personnel discuss how they are turning big data into power with the energy data platform and apps.

  2. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    ScienceCinema (OSTI)

    Secretary Chu

    2010-09-01

    Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of green jobs while helping reduce the nation?s dangerous dependence on foreign oil. The first three auto loans for advanced technologies were awarded to Ford Motor Company, Nissan Motors and Tesla Motors.

  3. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    SciTech Connect (OSTI)

    Secretary Chu

    2009-07-16

    Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of green jobs while helping reduce the nations dangerous dependence on foreign oil. The first three auto loans for advanced technologies were awarded to Ford Motor Company, Nissan Motors and Tesla Motors.

  4. Pollution prevention opportunity assessment for Facilities Maintenance Team (FMT) paint shop.

    SciTech Connect (OSTI)

    Klossner, Kristin Ann

    2003-05-01

    This Pollution Prevention Opportunity Assessment (PPOA) was conducted for Sandia National Laboratories/California Facilities Maintenance Team Paint Shop Operations in August and September 2002. The primary purpose of this PPOA is to provide recommendations to assist Paint Shop personnel in reducing the generation of waste and improving the efficiency of their processes. This report contains a summary of the information collected and analyses performed and recommends options for implementation. The Sandia National Laboratories Pollution Prevention staff will continue to work with the Paint Shop to implement the recommendations.

  5. New Lighting Facts Label: Takes the Guess Work Out of Shopping...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs January 25, 2012 - 5:52am Addthis Chris Stewart Senior Communicator at DOE's National Renewable ...

  6. From Shop Floor to Top Floor: Best Business Practices in Energy Efficiency

    Broader source: Energy.gov [DOE]

    This document is the presentation delivered on the Pew Center on Global Climate Change's report From Shop Floor to Top Floor: Best Business Practices in Energy Efficiency, which describes leading corporate energy efficiency programs.

  7. Secretary Chu Speaks at the 2010 Washington Auto Show

    SciTech Connect (OSTI)

    Secretary Chu

    2010-02-03

    Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need at the 2010 Washington Auto Show. He also announced that the Department of Energy had closed on a $1.4 billion loan to Nissan to build the all-electric LEAF in Tennessee and create up to 1,300 American jobs.

  8. Research Shows Ventilated Auto Seats Improve Fuel Economy, Comfort - News

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Releases | NREL Research Shows Ventilated Auto Seats Improve Fuel Economy, Comfort March 2, 2006 Golden, Colo. - The U.S. Department of Energy's National Renewable Energy Laboratory (NREL) has demonstrated that ventilated automotive seats not only can improve passenger comfort but also a vehicle's fuel economy. That's because ventilated seats keep drivers and passengers cooler, so they need less air conditioning to be comfortable. NREL's Vehicle Ancillary Loads Reduction team has been

  9. Secretary Chu Speaks at the 2010 Washington Auto Show

    ScienceCinema (OSTI)

    Secretary Chu

    2010-09-01

    Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need at the 2010 Washington Auto Show. He also announced that the Department of Energy had closed on a $1.4 billion loan to Nissan to build the all-electric LEAF in Tennessee and create up to 1,300 American jobs.

  10. Inspect and Repair Steam Traps

    SciTech Connect (OSTI)

    Not Available

    2006-01-01

    This revised ITP tip sheet on inspecting and repairing steam traps provide how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.

  11. RCRA Facility Investigation/Remedial Investigation Report with the Baseline Risk Assessment for the 716-A Motor Shops Seepage Basin

    SciTech Connect (OSTI)

    Palmer, E.

    1997-08-25

    This document describes the RCRA Facility Investigation/Remedial Investigation/Baseline Risk Assessment of the 716-A Motor Shops Seepage Basin.

  12. Motor Repair Tech Brief | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Repair Tech Brief Motor Repair Tech Brief This Tech Brief answers: Why do motors fail? When should you repair instead of replace? And how can reliability and efficiency be assured in a repair? PDF icon Motor Repair Tech Brief (March 2000) More Documents & Publications Extend the Operating Life of Your Motor Service Center Evaluation Guide Premium Efficiency Motor Selection and Application Guide - A Handbook for Industry

  13. David Friedman: On the Future of Transportation and the LA Auto Show |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy David Friedman: On the Future of Transportation and the LA Auto Show David Friedman: On the Future of Transportation and the LA Auto Show Addthis Description David Friedman, Principal Deputy Assistant Secretary in the Energy Department's Office of Energy Efficiency & Renewable Energy (EERE), visited the L.A. Auto Show in November 2015. In this video interview, he shared his thoughts about transportation's future, the exciting technologies being introduced to the

  14. U.S. Department of Energy Issues Rules for Auto Loan Program...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5.9 Billion Loan for Ford Motor Company Obama Administration Awards First Three Auto Loans for Advanced Technologies to Ford Motor Company, Nissan Motors and Tesla Motors...

  15. Secretary Chu to Deliver Keynote on EV Everywhere Grand Challenge at Washington Auto Show

    Broader source: Energy.gov [DOE]

    Thursday, January 31, 2013, Secretary Chu will deliver the government keynote address at the Washington Auto Show’s Public Policy Day

  16. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William

    2010-04-27

    Methods for promoting and suppressing auto-induction of transcription of cloned DNA in cultures of T7 expression strains are disclosed.

  17. Cyber-Intrusion Auto-Response Policy and Management System (CAPMS...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cyber-Intrusion Auto-Response Policy and Management System (CAPMS) A managed security system ... as a full partner in grid operations workflow imulation dissemination of emerging ...

  18. Selected Bibliography on Electric Motor Repair | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Selected Bibliography on Electric Motor Repair Selected Bibliography on Electric Motor Repair The following series of repair documents related to electric motors were produced by...

  19. New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bulbs | Department of Energy Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs New Lighting Facts Label: Takes the Guess Work Out of Shopping for Light Bulbs January 25, 2012 - 5:52am Addthis Chris Stewart Senior Communicator at DOE's National Renewable Energy Laboratory If you're like me, it sometimes feels overwhelming standing at the store and staring at a big wall of light bulbs, trying to understand all the lighting choices. With new lighting standards taking

  20. PERI - Auto-tuning Memory Intensive Kernels for Multicore

    SciTech Connect (OSTI)

    Bailey, David H; Williams, Samuel; Datta, Kaushik; Carter, Jonathan; Oliker, Leonid; Shalf, John; Yelick, Katherine; Bailey, David H

    2008-06-24

    We present an auto-tuning approach to optimize application performance on emerging multicore architectures. The methodology extends the idea of search-based performance optimizations, popular in linear algebra and FFT libraries, to application-specific computational kernels. Our work applies this strategy to Sparse Matrix Vector Multiplication (SpMV), the explicit heat equation PDE on a regular grid (Stencil), and a lattice Boltzmann application (LBMHD). We explore one of the broadest sets of multicore architectures in the HPC literature, including the Intel Xeon Clovertown, AMD Opteron Barcelona, Sun Victoria Falls, and the Sony-Toshiba-IBM (STI) Cell. Rather than hand-tuning each kernel for each system, we develop a code generator for each kernel that allows us to identify a highly optimized version for each platform, while amortizing the human programming effort. Results show that our auto-tuned kernel applications often achieve a better than 4X improvement compared with the original code. Additionally, we analyze a Roofline performance model for each platform to reveal hardware bottlenecks and software challenges for future multicore systems and applications.

  1. Energy Secretary Moniz at the 2016 Washington Auto Show | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Secretary Moniz at the 2016 Washington Auto Show Energy Secretary Moniz at the 2016 Washington Auto Show Addthis Topic Loans Alternative Fuel Vehicles Hydrogen Hydrogen & Fuel Cells Learn about some of the amazing Energy Department-supported vehicle technologies that are lowering carbon pollution and driving America's clean energy economy forward.

  2. Workshop on coatings needs in the auto industry

    SciTech Connect (OSTI)

    Courtright, E.L.

    1993-05-01

    New lightweight materials continue to be of great interest to the automotive industry. Compared to 20 years ago, the average vehicle weight has been reduced by almost a fourth, and fuel economy has nearly doubled. While continued improvements are both desirable and possible, materials choices are narrowing and the manufacturing methods needed to produce advanced materials systems are much more costly. The incentives remain high, however; particularly in view of large payoffs associated with minimizing structural weight in electric and hybrid-type vehicles. One generic solution is to develop coatings that will enable the use of lower cost materials. A workshop on coatings needs in the auto industry was held in Detroit, Michigan on October 27 and 28, 1992 with the objective of identifying research needs where coatings could enhance the use of energy efficient lightweight materials for automotive applications. Four generic areas had previously been identified auto manufacturers and industry suppliers. These were: Wear Coatings, Hard Protective Coatings for Plastics, Solar Control Coatings, and Process Manufacturing Issues. The development of coatings and coating technologies for lightweight metals and metal matrix composites emerged as the number one research needs. This need underscores the interest in making better use of existing lightweight metals, e.g. magnesium, aluminum, and their alloys. Coatings to protect plastics and reinforced plastic composites were also identified as a major area of importance. Protection from automotive liquids and gases. Coatings that will improve mar resistance, resist UV degradation, or eliminate degradation due to moisture absorption are also needed. Accordingly, manufacturability issues associated with coating light metals, e.g. aluminum, magnesium, and metal matrix composites with wear and corrosion resistant materials, were identified as a high priority research need.

  3. David Friedman: On the Future of Transportation and the L.A. Auto Show |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy David Friedman: On the Future of Transportation and the L.A. Auto Show David Friedman: On the Future of Transportation and the L.A. Auto Show January 6, 2016 - 8:45am Addthis A conversation with David Friedman, Principal Deputy Assistant Secretary, Office of Energy Efficiency & Renewable Energy on his visit to the L.A. Auto Show in November 2015 Drew Bittner Writer/Editor, Office of Energy Efficiency and Renewable Energy David Friedman, Principal Deputy Assistant

  4. Decreasing Beam Auto Tuning Interruption Events with In-Situ Chemical Cleaning on Axcelis GSD

    SciTech Connect (OSTI)

    Fuchs, Dieter; Spreitzer, Stefan; Vogl, Josef [Infineon Technologies AG., Wernerwerkstr.2, 93049 Regensburg (Germany); Bishop, Steve; Eldridge, David; Kaim, Robert [ATMI Inc., 7 Commerce Drive, Danbury, CT 06810 (United States)

    2008-11-03

    Ion beam auto tuning time and success rate are often major factors in the utilization and productivity of ion implanters. Tuning software frequently fails to meet specified setup times or recipe parameters, causing production stoppages and requiring manual intervention. Build-up of conductive deposits in the arc chamber and extraction gap can be one of the main causes of auto tuning problems. The deposits cause glitching and ion beam instabilities, which lead to errors in the software optimization routines. Infineon Regensburg has been testing use of XeF{sub 2}, an in-situ chemical cleaning reagent, with positive results in reducing auto tuning interruption events.

  5. Central Shops Burning/Rubble Pit 631-6G Additonal Sampling and Monitor Well Installation Report

    SciTech Connect (OSTI)

    Palmer, E.

    1995-02-01

    The Central Shops Burning/Rubble Pit 631-6G was constructed in 1951 as an unlined earthen pit in surficial sediments for disposal and incineration of potentially hazardous substances, such as metals and organic solvents.

  6. Summary of the 1987 soil sampling effort at the Idaho National Engineering Laboratory Test Reactor Area Paint Shop Ditch

    SciTech Connect (OSTI)

    Wood, T.R.; Knight, J.L.; Hertzler, C.L.

    1989-08-01

    Sampling of the Test Reactor Area (TRA) Paint Shop Ditch at the Idaho National Engineering Laboratory was initiated in compliance with the Interim Agreement between the Department of Energy (DOE) and the Environmental Protection Agency (EPA). Sampling of the TRA Paint Shop Ditch was done as part of the Action Plan to achieve and maintain compliance with the Resource Conservation and Recovery Act (RCRA) and applicable regulations. It is the purpose of this document to provide a summary of the July 6, 1987 sampling activities that occurred in ditch west of Building TRA-662, which housed the TRA Paint Shop in 1987. This report will give a narrative description of the field activities, locations of collected samples, discuss the sampling procedures and the chemical analyses. Also included in the scope of this report is to bring together data and reports on the TRA Paint Shop Ditch for archival purposes. 6 refs., 10 figs., 8 tabs.

  7. New Videos: Stories of Auto-Rickshaws in India | Open Energy...

    Open Energy Info (EERE)

    the videos highlight everyday stories of people who rely on auto-rickshaws for work, education and leisure. References Retrieved from "http:en.openei.orgwindex.php?titleNewV...

  8. Crashworthiness Assessment of Auto-body Members Considering the Fabrication Histories

    SciTech Connect (OSTI)

    Huh, Hoon; Song, Jung-Han; Kim, Kee-Poong; Kim, Hyun-Sub

    2005-08-05

    This paper is concerned with crashworthiness of auto-body members considering the effect of fabrication. Most auto-body members are fabricated with sheet metal forming process and welding process that induce fabrication histories such as the plastic work hardening, non-uniform thickness distribution and residual stress. Crash simulation is carried out for auto-body members with LS-DYNA3D in order to identify the fabrication effect on the crashworthiness. The analysis calculated crash mode, the reaction force and the energy absorption for crashworthiness assessment with the forming effect. The result shows that the crash analysis with considering the forming history leads to a different result from that without considering the forming effect. The analysis results demonstrate that the design of auto-body members should be carried out considering the forming history for accurate assessment of the crashworthiness.

  9. Thursday: Secretary Moniz to Make Remarks at the Washington Auto Show

    Broader source: Energy.gov [DOE]

    Tomorrow, Energy Secretary Ernest Moniz will attend the Washington Auto Show and make an important announcement about supporting the U.S. clean energy economy and the 21st century automotive industry.

  10. Distribution System Audits, Leak Detection, and Repair: Kirtland Air Force Base Leak Detection and Repair Program

    SciTech Connect (OSTI)

    2009-01-14

    Water Best Management Practice #3 Fact Seet: Outlines how a leak detection and repair program helped Kirtland Air Force Base perform distribution system audits, leak detection, and repair to conserve water site-wide.

  11. Open | SpeedShop: An Open Source Infrastructure for Parallel Performance Analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Schulz, Martin; Galarowicz, Jim; Maghrak, Don; Hachfeld, William; Montoya, David; Cranford, Scott

    2008-01-01

    Over the last decades a large number of performance tools has been developed to analyze and optimize high performance applications. Their acceptance by end users, however, has been slow: each tool alone is often limited in scope and comes with widely varying interfaces and workflow constraints, requiring different changes in the often complex build and execution infrastructure of the target application. We started the Open | SpeedShop project about 3 years ago to overcome these limitations and provide efficient, easy to apply, and integrated performance analysis for parallel systems. Open | SpeedShop has two different faces: it provides an interoperable tool set covering themore » most common analysis steps as well as a comprehensive plugin infrastructure for building new tools. In both cases, the tools can be deployed to large scale parallel applications using DPCL/Dyninst for distributed binary instrumentation. Further, all tools developed within or on top of Open | SpeedShop are accessible through multiple fully equivalent interfaces including an easy-to-use GUI as well as an interactive command line interface reducing the usage threshold for those tools.« less

  12. EERE Success Story-EERE and Auto Manufacturers Demonstrate and Evaluate

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fuel Cell Vehicles | Department of Energy EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles EERE Success Story-EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles April 18, 2013 - 12:00am Addthis The National Fuel Cell Electric Vehicle Learning Demonstration-funded and managed by EERE-has tested, demonstrated, and validated fuel cell electric vehicles and hydrogen infrastructure in real-world environments. The project found that these vehicles

  13. INTERNAL REPAIR OF PIPELINES REVIEW & EVALUATION OF INTERNAL PIPELINE REPAIR TRIALS REPORT

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-09-01

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is generally ineffective at restoring the pressure containing capabilities of pipelines. Failure pressure for pipe repaired with carbon fiber-reinforced composite liner was greater than that of the un-repaired pipe section with damage, indicating that this type of liner is effective at restoring the pressure containing capability of pipe. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the next phase of this project.

  14. Leveraging Service Calls and Emergency Repairs for Energy Efficiency...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Service Calls and Emergency Repairs for Energy Efficiency Marketing Leveraging Service Calls and Emergency Repairs for Energy Efficiency Marketing Better Buildings Residential ...

  15. Solar Water Heating System Maintenance and Repair | Department...

    Energy Savers [EERE]

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair Rooftop solar water heaters need regular maintenance to operate at peak efficiency. | ...

  16. Solar Water Heating System Maintenance and Repair | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair Rooftop solar water heaters need regular maintenance to operate at peak efficiency. |...

  17. DOE/SC-ARM-09-023 Ordering ARM Data One-Stop Shopping: Getting the

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    23 Ordering ARM Data One-Stop Shopping: Getting the Data You Need From the ARM Data Archive, www.archive.arm.gov, users can select routine data by browsing in the new ARM Data Discovery Tool-the first interface listed on the page. This tool features pre-selected sorts and search logic to help you find atmospheric and climate data faster. As each selection is made, only ARM data meeting the criteria remain visible, leading to the datastream that best suits your needs. When data are ordered, the

  18. Developments advance subsea pipelaying, inspection, repair

    SciTech Connect (OSTI)

    1997-09-15

    Recent advances in laying, inspecting, and repairing pipelines are helping to cut both costs and time. A new dredging system that employs jets to clear a subsea trench for pipelay received trials off Belgium last spring. Also, within the last year, projects in the Middle East and North Sea employed technologies that promise to make inspecting the surface of a subsea pipeline in difficult terrain easier, less time consuming, and therefore less costly. Plus, subsea repair of damaged pipelines may take less time with a new ``stabbable`` pipe connector. The paper describes jet dredging, inspection advance, support software, the North Sea site, and pipeline repair.

  19. U.S. Department of Energy Issues Rules for Auto Loan Program | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Issues Rules for Auto Loan Program U.S. Department of Energy Issues Rules for Auto Loan Program November 5, 2008 - 4:47pm Addthis WASHINGTON, DC - Today the U.S. Department of Energy issued an Interim Final Rule that implements the Advanced Technology Vehicles Manufacturing Incentive Program authorized by section 136 of the Energy Independence and Security Act of 2007 (EISA). The FY09 Continuing Resolution provided DOE with funding to make up to $25 billion in direct loans to

  20. Secretary Chu to Highlight Administration Support for U.S. Auto Industry in

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Detroit Economic Club Speech | Department of Energy to Highlight Administration Support for U.S. Auto Industry in Detroit Economic Club Speech Secretary Chu to Highlight Administration Support for U.S. Auto Industry in Detroit Economic Club Speech January 6, 2012 - 4:08pm Addthis Washington D.C. - U.S. Energy Secretary Steven Chu will travel to Detroit, Mich., next week to highlight the Obama Administration's support for the American automobile industry and the role investing in innovation

  1. A Guide to AC Motor Repair and Replacement

    SciTech Connect (OSTI)

    2004-03-01

    This booklet provides helpful information for making informed repair or replace decisions for electric motors.

  2. Window Replacement, Rehabilitation, & Repair Guides - Building...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Effec guid-window repair.jpg This Top Innovation describes research by Building Science Corporation to determine that whole-house energy savings of up to 10% can be achieved ...

  3. Window shopping

    SciTech Connect (OSTI)

    Best, D.

    1990-03-01

    The author addresses the energy efficiency of windows and describes changes and new products available in this consumer information article. Experiments currently being done by Lawrence Berkeley Laboratory (LBL), Bonneville Power Authority and the Washington State Energy Office show that some of these superwindows collect more energy from the sun than they let escape from inside the home. One type of window in current production is the low-E (low-emissivity) and the IGUs (insulated glass units). Low-E techniques include glazing of the glass with various materials including polyester and metallic coatings. Other measures include filling the airspace in double pane windows with argon, aerogel or by creating a vacuum in the airspace. Another factor the author considers is ultraviolet light protection.

  4. Model Repair Specifications for Low Voltage Induction Motors | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Model Repair Specifications for Low Voltage Induction Motors Model Repair Specifications for Low Voltage Induction Motors These Model Repair Specifications are intended to cover routine repair and rewind of low-voltage random-wound three-phase AC squirrel cage induction motors. PDF icon Model Repair Specifications for Low Voltage Induction Motors (November 1999) More Documents & Publications DOE Navigant Master Presentation Improving Motor and Drive System Performance - A

  5. Energy and Technology Review: Unlocking the mysteries of DNA repair

    SciTech Connect (OSTI)

    Quirk, W.A.

    1993-04-01

    DNA, the genetic blueprint, has the remarkable property of encoding its own repair following diverse types of structural damage induced by external agents or normal metabolism. We are studying the interplay of DNA damaging agents, repair genes, and their protein products to decipher the complex biochemical pathways that mediate such repair. Our research focuses on repair processes that correct DNA damage produced by chemical mutagens and radiation, both ionizing and ultraviolet. The most important type of DNA repair in human cells is called excision repair. This multistep process removes damaged or inappropriate pieces of DNA -- often as a string of 29 nucleotides containing the damage -- and replaces them with intact ones. We have isolated, cloned, and mapped several human repair genes associated with the nucleotide excision repair pathway and involved in the repair of DNA damage after exposure to ultraviolet light or mutagens in cooked food. We have shown that a defect in one of these repair genes, ERCC2, is responsible for the repair deficiency in one of the groups of patients with the recessive genetic disorder xeroderma pigmentosum (XP group D). We are exploring ways to purify sufficient quantities (milligrams) of the protein products of these and other repair genes so that we can understand their functions. Our long-term goals are to link defective repair proteins to human DNA repair disorders that predispose to cancer, and to produce DNA-repair-deficient mice that can serve as models for the human disorders.

  6. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William

    2013-03-19

    A method for promoting and suppressing auto-induction of transcription of a cloned gene 1 of bacteriophage T7 in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells.

  7. Alkylation damage repair in mammalian genomes

    SciTech Connect (OSTI)

    Mitra, S.; Roy, R.; Kim, N.K. |; Tano, K. |; Ibeanu, G.C. |; Dunn, W.C.; Natarajan, A.T.; Hartenstein, B.; Kaina, B.

    1992-11-01

    The repair of O{sup 6} -alkylguanine in DNA involves only O{sup 6} -methyltransferase (MGMT) while the repair of N-alkylpurines requires multiple proteins including N-methylpurine-DNA glycosylase (MPG). While the biochemical properties human and mouse MGMTs are very similar, the mouse MPG removes 7-methylguanine more efficiently than the human protein. An increased level of MGMT, without a change in the level of MPG associated with gene amplification, was observed in a mouse cell line resistant to 2-chloroethyl-N-nitrosourea. In contrast, no correlation was observed between MPG level and resistance to methyl methanesulfonate in Chinese hamster ovary (CHO) cells. This result suggests a protein other than MPG limits the repair rate of N-alkylpurine in CHO cells.

  8. Alkylation damage repair in mammalian genomes

    SciTech Connect (OSTI)

    Mitra, S.; Roy, R.; Kim, N.K. . Sealy Center for Molecular Science Oak Ridge National Lab., TN ); Tano, K. Oak Ridge National Lab., TN ); Ibeanu, G.C. Oak Ridge National Lab., TN ); Dunn, W.C. (

    1992-01-01

    The repair of O{sup 6} -alkylguanine in DNA involves only O{sup 6} -methyltransferase (MGMT) while the repair of N-alkylpurines requires multiple proteins including N-methylpurine-DNA glycosylase (MPG). While the biochemical properties human and mouse MGMTs are very similar, the mouse MPG removes 7-methylguanine more efficiently than the human protein. An increased level of MGMT, without a change in the level of MPG associated with gene amplification, was observed in a mouse cell line resistant to 2-chloroethyl-N-nitrosourea. In contrast, no correlation was observed between MPG level and resistance to methyl methanesulfonate in Chinese hamster ovary (CHO) cells. This result suggests a protein other than MPG limits the repair rate of N-alkylpurine in CHO cells.

  9. Repairable chip bonding/interconnect process

    DOE Patents [OSTI]

    Bernhardt, A.F.; Contolini, R.J.; Malba, V.; Riddle, R.A.

    1997-08-05

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules is disclosed. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder. 10 figs.

  10. Repairable chip bonding/interconnect process

    DOE Patents [OSTI]

    Bernhardt, Anthony F.; Contolini, Robert J.; Malba, Vincent; Riddle, Robert A.

    1997-01-01

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder.

  11. AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery

    SciTech Connect (OSTI)

    Tsai, Yingssu; McPhillips, Scott E.; Gonzlez, Ana; McPhillips, Timothy M.; Zinn, Daniel; Cohen, Aina E.; Feese, Michael D.; Bushnell, David; Tiefenbrunn, Theresa; Stout, C. David; Ludaescher, Bertram; Hedman, Britt; Hodgson, Keith O.; Soltis, S. Michael

    2013-05-01

    New software has been developed for automating the experimental and data-processing stages of fragment-based drug discovery at a macromolecular crystallography beamline. A new workflow-automation framework orchestrates beamline-control and data-analysis software while organizing results from multiple samples. AutoDrug is software based upon the scientific workflow paradigm that integrates the Stanford Synchrotron Radiation Lightsource macromolecular crystallography beamlines and third-party processing software to automate the crystallography steps of the fragment-based drug-discovery process. AutoDrug screens a cassette of fragment-soaked crystals, selects crystals for data collection based on screening results and user-specified criteria and determines optimal data-collection strategies. It then collects and processes diffraction data, performs molecular replacement using provided models and detects electron density that is likely to arise from bound fragments. All processes are fully automated, i.e. are performed without user interaction or supervision. Samples can be screened in groups corresponding to particular proteins, crystal forms and/or soaking conditions. A single AutoDrug run is only limited by the capacity of the sample-storage dewar at the beamline: currently 288 samples. AutoDrug was developed in conjunction with RestFlow, a new scientific workflow-automation framework. RestFlow simplifies the design of AutoDrug by managing the flow of data and the organization of results and by orchestrating the execution of computational pipeline steps. It also simplifies the execution and interaction of third-party programs and the beamline-control system. Modeling AutoDrug as a scientific workflow enables multiple variants that meet the requirements of different user groups to be developed and supported. A workflow tailored to mimic the crystallography stages comprising the drug-discovery pipeline of CoCrystal Discovery Inc. has been deployed and successfully demonstrated. This workflow was run once on the same 96 samples that the group had examined manually and the workflow cycled successfully through all of the samples, collected data from the same samples that were selected manually and located the same peaks of unmodeled density in the resulting difference Fourier maps.

  12. Solar Water Heating System Maintenance and Repair | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Water Heating System Maintenance and Repair Solar Water Heating System Maintenance and Repair May 30, 2012 - 2:35pm Addthis Rooftop solar water heaters need regular maintenance to...

  13. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... It turns out that ATL bridges two DNA repair pathways (base repair and nucleotide excision ... By mapping conservation of amino acid sequences between their ATL and sequences in other ...

  14. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William

    2010-07-20

    A bacterial growth medium for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a lac repressor. Also disclosed is a bacterial growth medium for improving the production of a selenomethionine-containing protein or polypeptide in a bacterial cell, the protein or polypeptide being produced by recombinant DNA techniques from a lac or T7lac promoter, the bacterial cell encoding a vitamin B12-dependent homocysteine methylase. Finally, disclosed is a bacterial growth medium for suppressing auto-induction of expression in cultures of bacterial cells grown batchwise, said transcription being under the control of lac repressor.

  15. Aircraft Propeller Hub Repair (Technical Report) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Technical Report: Aircraft Propeller Hub Repair Citation Details In-Document Search Title: Aircraft Propeller Hub Repair The team performed a literature review, conducted residual stress measurements, performed failure analysis, and demonstrated a solid state additive manufacturing repair technique on samples removed from a scrapped propeller hub. The team evaluated multiple options for hub repair that included existing metal buildup technologies that the Federal Aviation Administration (FAA)

  16. Selected Bibliography on Electric Motor Repair | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Selected Bibliography on Electric Motor Repair Selected Bibliography on Electric Motor Repair The following series of repair documents related to electric motors were produced by the U.S. Department of Energy's Advanced Manufacturing Office (formerly the Office of Industrial Technologies) with input from trade associations, consulting companies, manufacturers, non-profit operations, and others. PDF icon Selected Bibliography on Electric Motor Repair (November 1999) More Documents &

  17. Antibody specific for a DNA repair protein

    DOE Patents [OSTI]

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-07-11

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  18. DNA encoding a DNA repair protein

    DOE Patents [OSTI]

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-08-15

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  19. Component Repair Times Obtained from MSPI Data

    SciTech Connect (OSTI)

    Eide, Steven A.

    2015-05-01

    Information concerning times to repair or restore equipment to service given a failure is valuable to probabilistic risk assessments (PRAs). Examples of such uses in modern PRAs include estimation of the probability of failing to restore a failed component within a specified time period (typically tied to recovering a mitigating system before core damage occurs at nuclear power plants) and the determination of mission times for support system initiating event (SSIE) fault tree models. Information on equipment repair or restoration times applicable to PRA modeling is limited and dated for U.S. commercial nuclear power plants. However, the Mitigating Systems Performance Index (MSPI) program covering all U.S. commercial nuclear power plants provides up-to-date information on restoration times for a limited set of component types. This paper describes the MSPI program data available and analyzes the data to obtain median and mean component restoration times as well as non-restoration cumulative probability curves. The MSPI program provides guidance for monitoring both planned and unplanned outages of trains of selected mitigating systems deemed important to safety. For systems included within the MSPI program, plants monitor both train UA and component unreliability (UR) against baseline values. If the combined system UA and UR increases sufficiently above established baseline results (converted to an estimated change in core damage frequency or CDF), a “white” (or worse) indicator is generated for that system. That in turn results in increased oversight by the US Nuclear Regulatory Commission (NRC) and can impact a plant’s insurance rating. Therefore, there is pressure to return MSPI program components to service as soon as possible after a failure occurs. Three sets of unplanned outages might be used to determine the component repair durations desired in this article: all unplanned outages for the train type that includes the component of interest, only unplanned outages associated with failures of the component of interest, and only unplanned outages associated with PRA failures of the component of interest. The paper will describe how component repair times can be generated from each set and which approach is most applicable. Repair time information will be summarized for MSPI pumps and diesel generators using data over 2003 – 2007. Also, trend information over 2003 – 2012 will be presented to indicate whether the 2003 – 2007 repair time information is still considered applicable. For certain types of pumps, mean repair times are significantly higher than the typically assumed 24 h duration.

  20. Emergency pipe line repair connects subsea pipe lines

    SciTech Connect (OSTI)

    Lerique, M.P.; Thiberge, P. ); Wright, N. )

    1990-11-01

    Emergency repair of any subsea line pipe must form a high-integrity, metal-to-metal seal. This paper presents a remote, diverless repair system that utilizes master flanges, a connector and a spool piece to repair line pipe in deep offshore waters.

  1. Effect of polarization and focusing on laser pulse driven auto-resonant particle acceleration

    SciTech Connect (OSTI)

    Sagar, Vikram; Sengupta, Sudip; Kaw, Predhiman [Institute for Plasma Research, Bhat, Gandhinagar-382428 (India)] [Institute for Plasma Research, Bhat, Gandhinagar-382428 (India)

    2014-04-15

    The effect of laser polarization and focusing is theoretically studied on the final energy gain of a particle in the Auto-resonant acceleration scheme using a finite duration laser pulse with Gaussian shaped temporal envelope. The exact expressions for dynamical variables viz. position, momentum, and energy are obtained by analytically solving the relativistic equation of motion describing particle dynamics in the combined field of an elliptically polarized finite duration pulse and homogeneous static axial magnetic field. From the solutions, it is shown that for a given set of laser parameters viz. intensity and pulse length along with static magnetic field, the energy gain by a positively charged particle is maximum for a right circularly polarized laser pulse. Further, a new scheme is proposed for particle acceleration by subjecting it to the combined field of a focused finite duration laser pulse and static axial magnetic field. In this scheme, the particle is initially accelerated by the focused laser field, which drives the non-resonant particle to second stage of acceleration by cyclotron Auto-resonance. The new scheme is found to be efficient over two individual schemes, i.e., auto-resonant acceleration and direct acceleration by focused laser field, as significant particle acceleration can be achieved at one order lesser values of static axial magnetic field and laser intensity.

  2. Implementation of a solvent management program to control paint shop volatile organic compounds

    SciTech Connect (OSTI)

    Floer, M.M.; Hicks, B.H.

    1997-12-31

    The majority of automobile assembly plant volatile organic compound (VOC) emissions are generated from painting operations. Typical paint operations generate more than 90 percent of the total plant emissions and, up to, 50 percent can be released by cleaning sources. Plant practices which contribute to the release of VOC emissions include the cleaning of paint lines and equipment, tanks, spray booths, floors and vehicles. Solvents continue to be the largest contributing source of VOC emissions in an automotive paint shop. To reduce overall VOC emissions, environmental regulations and guidelines were introduced under the Clean Air Act; Pollution Prevention and Waste Minimization programs, Control Techniques, and special air permit conditions. The introduction of these regulations and guidelines has driven industry toward continual refinement of their present cleaning methods while pursuing new techniques and technologies. Industry has also shown a proactive approach by introducing new waterborne and powder coating paint technologies to reduce overall emissions. As new paint technologies are developed and introduced, special attention must be given to the types of materials utilized for cleaning. The development and implementation of a solvent management program allows a facility to standardize a program to properly implement materials, equipment, technologies and work practices to reduce volatile organic compound emissions, meet strict cleaning requirements posed by new paint technologies and produce a vehicle which meets the high quality standards of the customer. This paper will assess the effectiveness of a solvent management program by examining pollution prevention initiatives and data from four different painting operations.

  3. Helium bubble distributions in reactor tank repair specimens. Part 1

    SciTech Connect (OSTI)

    Tosten, M.H.; Kestin, P.A.

    1992-03-01

    This report discusses the Reactor Tank Repair (RTR) program was initiated to develop an in-tank repair process capable of repairing stress corrosion cracks within the SRS reactor tank walls, in the event that such a repair is needed. Previous attempts to repair C-reactor tank with a gas tungsten arc (GTA) welding process were unsuccessful due to significant cracking that occurred in the heat-affected-zones adjacent to the repair welds. It was determined that this additional cracking was a result of helium embrittlement caused by the combined effects of helium (existing within the tank walls), the high heat input associated with the GTA process, and weld shrinkage stresses. Based on the results of earlier studies it was suggested that the effects of helium embrittlement could be minimized by using a low heat input GMA process. Metallographic analysis played an important role throughout the investigation of alternative welding methods for the repair of helium-containing materials.

  4. Helium bubble distributions in reactor tank repair specimens

    SciTech Connect (OSTI)

    Tosten, M.H.; Kestin, P.A.

    1992-03-01

    This report discusses the Reactor Tank Repair (RTR) program was initiated to develop an in-tank repair process capable of repairing stress corrosion cracks within the SRS reactor tank walls, in the event that such a repair is needed. Previous attempts to repair C-reactor tank with a gas tungsten arc (GTA) welding process were unsuccessful due to significant cracking that occurred in the heat-affected-zones adjacent to the repair welds. It was determined that this additional cracking was a result of helium embrittlement caused by the combined effects of helium (existing within the tank walls), the high heat input associated with the GTA process, and weld shrinkage stresses. Based on the results of earlier studies it was suggested that the effects of helium embrittlement could be minimized by using a low heat input GMA process. Metallographic analysis played an important role throughout the investigation of alternative welding methods for the repair of helium-containing materials.

  5. SU-E-I-97: Smart Auto-Planning Framework in An EMR Environment (SAFEE)

    SciTech Connect (OSTI)

    Zhang, B; Chen, S; Mutaf, Y; Prado, K; D'Souza, W

    2014-06-01

    Purpose: Our Radiation Oncology Department uses clinical practice guidelines for patient treatment, including normal tissue sparing and other dosimetric constraints. These practice guidelines were adapted from national guidelines, clinical trials, literature reviews, and practitioner's own experience. Modern treatment planning systems (TPS) have the capability of incorporating these practice guidelines to automatically create radiation therapy treatment plans with little human intervention. We are developing a software infrastructure to integrate clinical practice guidelines and radiation oncology electronic medical record (EMR) system into radiation therapy treatment planning system (TPS) for auto planning. Methods: Our Smart Auto-Planning Framework in an EMR environment (SAFEE) uses a software pipeline framework to integrate practice guidelines,EMR, and TPS together. The SAFEE system starts with retrieving diagnosis information and physician's prescription from the EMR system. After approval of contouring, SAFEE will automatically create plans according to our guidelines. Based on clinical objectives, SAFEE will automatically select treatment delivery techniques (such as, 3DRT/IMRT/VMAT) and optimize plans. When necessary, SAFEE will create multiple treatment plans with different combinations of parameters. SAFEE's pipeline structure makes it very flexible to integrate various techniques, such as, Model-Base Segmentation (MBS) and plan optimization algorithms, e.g., Multi-Criteria Optimization (MCO). In addition, SAFEE uses machine learning, data mining techniques, and an integrated database to create clinical knowledgebase and then answer clinical questions, such as, how to score plan quality or how volume overlap affects physicians' decision in beam and treatment technique selection. Results: In our institution, we use Varian Aria EMR system and RayStation TPS from RaySearch, whose ScriptService API allows control by external programs. These applications are the building blocks of our SAFEE system. Conclusion: SAFEE is a feasible method of integrating clinical information to develop an auto-planning paradigm to improve clinical workflow in cancer patient care.

  6. Restore: Modeling Repair and Restoration Processes | Argonne National

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory Restore: Modeling Repair and Restoration Processes Restore: Modeling Repair and Restoration Processes Argonne's Restore software models complex sets of steps required to accomplish a goal, such as repairing a ruptured natural gas pipeline, when the time required to complete a step may be uncertain. For example, external conditions (i.e., the time of day, weather, and availability of crew) may affect one or more of the steps required to accomplish a goal. Therefore,

  7. Pulse-excited, auto-zeroing multiple channel data transmission system

    DOE Patents [OSTI]

    Fasching, G.E.

    1985-02-22

    A multiple channel data transmission system is provided in which signals from a plurality of pulse operated transducers and a corresponding plurality of pulse operated signal processor channels are multiplexed for single channel FM transmission to a receiving station. The transducers and corresponding channel amplifiers are powered by pulsing the dc battery power to these devices to conserve energy and battery size for long-term data transmission from remote or inaccessible locations. Auto zeroing of the signal channel amplifiers to compensate for drift associated with temperature changes, battery decay, component aging, etc., in each channel is accomplished by means of a unique auto zero feature which between signal pulses holds a zero correction voltage on an integrating capacitor coupled to the corresponding channel amplifier output. Pseudo-continuous outputs for each channel are achieved by pulsed sample-and-hold circuits which are updated at the pulsed operation rate. The sample-and-hold outputs are multiplexed into an FM/FM transmitter for transmission to an FM receiver station for demultiplexing and storage in separate channel recorders.

  8. Method for photolithographic definition of recessed features on a semiconductor wafer utilizing auto-focusing alignment

    DOE Patents [OSTI]

    Farino, Anthony J.; Montague, Stephen; Sniegowski, Jeffry J.; Smith, James H.; McWhorter, Paul J.

    1998-01-01

    A method is disclosed for photolithographically defining device features up to the resolution limit of an auto-focusing projection stepper when the device features are to be formed in a wafer cavity at a depth exceeding the depth of focus of the stepper. The method uses a focusing cavity located in a die field at the position of a focusing light beam from the auto-focusing projection stepper, with the focusing cavity being of the same depth as one or more adjacent cavities wherein a semiconductor device is to be formed. The focusing cavity provides a bottom surface for referencing the focusing light beam and focusing the stepper at a predetermined depth below the surface of the wafer, whereat the device features are to be defined. As material layers are deposited in each device cavity to build up a semiconductor structure such as a microelectromechanical system (MEMS) device, the same material layers are deposited in the focusing cavity, raising the bottom surface and re-focusing the stepper for accurately defining additional device features in each succeeding material layer. The method is especially applicable for forming MEMS devices within a cavity or trench and integrating the MEMS devices with electronic circuitry fabricated on the wafer surface.

  9. Method for photolithographic definition of recessed features on a semiconductor wafer utilizing auto-focusing alignment

    DOE Patents [OSTI]

    Farino, A.J.; Montague, S.; Sniegowski, J.J.; Smith, J.H.; McWhorter, P.J.

    1998-07-21

    A method is disclosed for photolithographically defining device features up to the resolution limit of an auto-focusing projection stepper when the device features are to be formed in a wafer cavity at a depth exceeding the depth of focus of the stepper. The method uses a focusing cavity located in a die field at the position of a focusing light beam from the auto-focusing projection stepper, with the focusing cavity being of the same depth as one or more adjacent cavities wherein a semiconductor device is to be formed. The focusing cavity provides a bottom surface for referencing the focusing light beam and focusing the stepper at a predetermined depth below the surface of the wafer, whereat the device features are to be defined. As material layers are deposited in each device cavity to build up a semiconductor structure such as a microelectromechanical system (MEMS) device, the same material layers are deposited in the focusing cavity, raising the bottom surface and re-focusing the stepper for accurately defining additional device features in each succeeding material layer. The method is especially applicable for forming MEMS devices within a cavity or trench and integrating the MEMS devices with electronic circuitry fabricated on the wafer surface. 15 figs.

  10. Pulse-excited, auto-zeroing multiple channel data transmission system

    DOE Patents [OSTI]

    Fasching, George E.

    1987-01-01

    A multiple channel data transmission system is provided in which signals from a plurality of pulse operated transducers and a corresponding plurality of pulse operated signal processor channels are multiplexed for single channel FM transmission to a receiving station. The transducers and corresponding channel amplifiers are powered by pulsing the dc battery power to these devices to conserve energy and battery size for long-term data transmission from remote or inaccessible locations. Auto zeroing of the signal channel amplifiers to compensate for drift associated with temperature changes, battery decay, component aging, etc., in each channel is accomplished by means of a unique auto zero feature which between signal pulses holds a zero correction voltage on an integrating capacitor coupled to the corresponding channel amplifier output. Pseudo-continuous outputs for each channel are achieved by pulsed sample-and-hold circuits which are updated at the pulsed operation rate. The sample-and-hold outputs are multiplexed into an FM/FM transmitter for transmission to an FM receiver station for demultiplexing and storage in separate channel recorders.

  11. Aircraft Propeller Hub Repair (Technical Report) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    and demonstrated a solid state additive manufacturing repair technique on samples removed ... For new hubs, a machining practice to prevent fretting with the steel drive shaft ...

  12. SNL Researchers Assess Wind Turbine Blade Inspection and Repair...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... The results will also inform how blade inspections are conducted at manufacturing facilities and wind farms, thereby improving maintenance and repair procedures for wind turbine ...

  13. Model Repair Specifications for Low Voltage Induction Motors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... EASA AR100-1998 Recommended Practice For The Repair of Rotating Electrical Apparatus IEEE IEEE Std. 43, Recommended Practice for Testing Insulation Resistance of Rotating Machinery ...

  14. Inspect and Repair Steam Traps | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon Inspect and Repair Steam Traps (January 2012) More Documents & Publications Flash High-Pressure Condensate to Regenerate Low-Pressure Steam Steam Pressure Reduction: ...

  15. Window Replacement, Rehabilitation, & Repair Guides- Building America Top Innovation

    Broader source: Energy.gov [DOE]

    Building America team Building Science Corporation guides contractors through several options for repairing or replacing old windows to improve air sealing and thermal performance.

  16. Leveraging Service Calls and Emergency Repairs for Energy Efficiency Marketing

    Broader source: Energy.gov [DOE]

    Better Buildings Residential Network Peer Exchange Call Series: Leveraging Service Calls and Emergency Repairs, Call Slides and Discussion Summary, November 13, 2014.

  17. A plan for implementation of innovative hazardous waste minimization techniques at an eastern US Naval Plating Shop

    SciTech Connect (OSTI)

    Walker, J.F. Jr.; Villiers-Fisher, J.F.; Brown, C.H. Jr.

    1987-01-01

    Oak Ridge National Laboratory (ORNL) was contracted by the Naval Energy and Environmental Support Activity (NEESA) to analyze the wastewater problems at a Naval Ordnance Station (NOS) plating shop in the eastern United States to recommend innovative wastewater treatment technologies for handling those problems and to implement the recommended treatment technology. Hexavalent chromium was identified as the major problem area at NOS. Water conservation measures were recommended which would reduce the volume of chromium-contaminated wastewater from approximately 300 L/min to approximately 20 L/min. A treatment scheme consisting of RO followed by evaporation of the RO concentrate steam was recommended. Paint-stripping operations at NOS potentially contaminate the wastewater with phenol, trichloroethane, and possibly other organics. However, the need for a treatment unit for removal of organics could not be established due to a lack of organic analytical data. A characterization study was therefore recommended for the NOS plating shop. If treatment for organics is necessary, the treatment unit might include two-stage filtration for removal of paint flakes or other solids, air stripping for removal of volatile organics, and carbon adsorption for removal of residual organics. 7 refs., 6 figs., 3 tabs.

  18. Deep patch technique for landslide repair. Final report

    SciTech Connect (OSTI)

    Helwany, B.M.

    1994-10-01

    The report describes the laboratory testing of the `USFS deep patch` technique and a CTI modification of this technique for repairing landslides with geosynthetic reinforcement. The technique involves replacing sections of roadway lost due to landslides on top of a geosynthetically-reinforced embankment. The CTI modification involves replacing the reinforced slope with a geosynthetically-reinforced retaining wall with a truncated base. Both techniques rely on the cantilevering ability of the reinforced mass to limit the load on the foundation with a high slide potential. The tests with road base showed that (1) both the USFS and CTI repair reduced effectively the adverse effects of local landsliding on the highway pavement by preventing crack propagation; (2) the USFS repair increased the stability of the repaired slope, which was in progressive failure, by reducing the stresses exerted on it; and (3) the CTI repair produced substantially greater stresses on its foundation due to the truncated base of the reinforced mass.

  19. Evaluation of atlas-based auto-segmentation software in prostate cancer patients

    SciTech Connect (OSTI)

    Greenham, Stuart; Dean, Jenna; Fu, Cheuk Kuen Kenneth; Goman, Joanne; Mulligan, Jeremy; Tune, Deanna; Sampson, David; Westhuyzen, Justin; McKay, Michael

    2014-09-15

    The performance and limitations of an atlas-based auto-segmentation software package (ABAS; Elekta Inc.) was evaluated using male pelvic anatomy as the area of interest. Contours from 10 prostate patients were selected to create atlases in ABAS. The contoured regions of interest were created manually to align with published guidelines and included the prostate, bladder, rectum, femoral heads and external patient contour. Twenty-four clinically treated prostate patients were auto-contoured using a randomised selection of two, four, six, eight or ten atlases. The concordance between the manually drawn and computer-generated contours were evaluated statistically using Pearson's product–moment correlation coefficient (r) and clinically in a validated qualitative evaluation. In the latter evaluation, six radiation therapists classified the degree of agreement for each structure using seven clinically appropriate categories. The ABAS software generated clinically acceptable contours for the bladder, rectum, femoral heads and external patient contour. For these structures, ABAS-generated volumes were highly correlated with ‘as treated’ volumes, manually drawn; for four atlases, for example, bladder r = 0.988 (P < 0.001), rectum r = 0.739 (P < 0.001) and left femoral head r = 0.560 (P < 0.001). Poorest results were seen for the prostate (r = 0.401, P < 0.05) (four atlases); however this was attributed to the comparison prostate volume being contoured on magnetic resonance imaging (MRI) rather than computed tomography (CT) data. For all structures, increasing the number of atlases did not consistently improve accuracy. ABAS-generated contours are clinically useful for a range of structures in the male pelvis. Clinically appropriate volumes were created, but editing of some contours was inevitably required. The ideal number of atlases to improve generated automatic contours is yet to be determined.

  20. Bearing repair services offer a cost-effective alternative to expensive replacement

    SciTech Connect (OSTI)

    2009-02-15

    The article, based on a presentation during MINExpo 2008, explains how advancement is bearing design, material, maintenance and repair methods have greatly improved the potential for and popularity of bearing repair as an effective way to extend bearing life. The Trinken Co. offers a variety of service options including repair, recertification, reconditioning and remanufacturing. Benefits of a quality repair program are outlined. 2 photos.

  1. Intermediate hearth repair technique at Thyssen Stahl AG

    SciTech Connect (OSTI)

    Kowalski, W.; Bachhofen, H.J.; Ruether, P.; Ballewski, T.

    1996-12-31

    Nowadays various techniques for the fastest possible intermediate repair and/or emplacement of refractory materials above the tuyere level allow a significant extension of furnace campaign life. The latter are hence now exclusively determined by the service life of the hearth. The improvement of hearth monitoring and the estimation of residual brick strength of the refractory lining on the basis of temperature measurements in the hearth enable the location of individual zones of premature wear. These measurement methods, which were developed by Thyssen Stahl AG, aid the decision to undertake selective repair of the hearth. Three areas of repair are differentiated: taphole zone; hearth wall, localized; and hearth wall, extensive. This hearth repair method is described in this report using the example of hearth refurbishing blast furnace 8, Hamborn.

  2. To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 29, 2007 6:28 PM To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Larry, Regarding the planned line outage, scheduled for Feb. 20 through Mar...

  3. Battery, heal thyself: Inventing self-repairing batteries | Argonne...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Battery, heal thyself: Inventing self-repairing batteries By Louise Lerner * January 11, 2012 Tweet EmailPrint Imagine dropping your phone on the hard concrete sidewalk-but when...

  4. Inspect and Repair Steam Traps - Steam Tip Sheet #1

    SciTech Connect (OSTI)

    2012-01-31

    This revised AMO tip sheet on inspecting and repairing steam traps provides how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.

  5. Repairing Windows & Doors: How To's for the Handy Homeowner

    SciTech Connect (OSTI)

    2006-01-05

    This brochure contains tips for homeowners to repair windows and doors in their home that sustained hurricane damage. This publication is a part of the How To's for the Handy Homeowner Series.

  6. Repairing Roofs and Ceilings: How To's for the Handy Homeowner

    SciTech Connect (OSTI)

    2006-01-01

    This brochure provides handy homeowners with tips on how to properly repair roofs and ceilings in their homes that sustained damage during a hurricane. This publications is a part of the How To's for the Handy Homeowner Series.

  7. Repairing Walls & Floors: How To's for the Handy Homeowner

    SciTech Connect (OSTI)

    2006-01-09

    This brochure provides handy homeowners with tips on how to properly repair walls and floors in their homes that sustained damage during a hurricane. This publications is a part of the How To's for the Handy Homeowner Series.

  8. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protein Bridges DNA Base and Nucleotide Excision Repair Pathways Protein Bridges DNA Base and Nucleotide Excision Repair Pathways Print Wednesday, 28 October 2009 00:00 Alkyltransferase proteins (AGT) protect cells from the biological effects of DNA damage caused by the addition of alkyl groups (alkylation). Alkyltransferase-like proteins (ATLs) can do the same, but they lack the reactive cysteine residue that allows the alkyltransferase function, and the mechanism for cell protection has

  9. DNA repair photomachine: Dynamics and mechanism | Stanford Synchrotron

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Lightsource DNA repair photomachine: Dynamics and mechanism Wednesday, March 30, 2016 - 3:00pm SLAC, Redtail Hawk Conference Room 108A Speaker: Dongping Zhong, The Ohio State University Program Description UV radiation can damage DNA and such lesion may eventually lead to skin cancer. Photolyase, a photo-repair machine in nature, can revert such damage with high efficiency. Here, by integrating femtosecond spectroscopy and molecular biology, we have completely mapped out the entire

  10. Auto-ignition during instationary jet evolution of dimethyl ether (DME) in a high-pressure atmosphere

    SciTech Connect (OSTI)

    Fast, G.; Kuhn, D.; Class, A.G.; Maas, U.

    2009-01-15

    The auto-ignition process during transient injection of gaseous dimethyl ether (DME) in a constant high-pressure atmosphere is studied experimentally by laser-optical methods and compared with numerical calculations. With different non-intrusive measurement techniques jet properties and auto-ignition are investigated at high temporal and spatial resolution. The open jet penetrates a constant pressure oxidative atmosphere of up to 4 MPa. During the transient evolution, the fuel jet entrains air at up to 720 K. The subsequent auto-ignition of the ignitable part of the jet occurs simultaneously over a wide spatial extension. The ignition delay times are not affected by variation of the nozzle exit velocity. Thus, the low-temperature oxidation is slow compared with the shorter time scales of mixing, so that chemical kinetics is dominating the process. The typical two-stage ignition is resolved optically with high-speed shadowgraphy at a sampling rate of 10 kHz. The 2D fields of jet velocity and transient mixture fraction are measured phase-coupled with Particle Image Velocimetry (PIV) and Tracer Laser Induced Fluorescence (LIF) during the time-frame of ignition. The instationary Probability Density Functions (PDF) of mixture fraction are described very well by Beta functions within the complete area of the open jet. Additional 1D flamelet simulations of the auto-ignition process are computed with a detailed reaction mechanism for DME [S. Fischer, F. Dryer, H. Curran, Int. J. Chem. Kinet. 32 (12) (2000) 713-740; H. Curran, S. Fischer, F. Dryer, Int. J. Chem. Kinet. 32 (12) (2000) 741-759]. Calculated ignition delay times are in very good agreement with the measured mean ignition delay times of 3 ms. Supplemental flamelet simulations address the influence of DME and air temperature, pressure and strain. Underneath a critical strain rate the air temperature is identified to be the most sensitive factor on ignition delay time. (author)

  11. Demonstration of automated price response in large customers in New York City using Auto-DR and OpenADR

    SciTech Connect (OSTI)

    Kim, Joyce Jihyun; Schetrit, Oren; Yin, Rongxin; Kiliccote, Sila

    2014-05-01

    Demand response (DR) – allowing customers to respond to reliability requests and market prices by changing electricity use from their normal consumption pattern – continues to be seen as an attractive means of demand-side management and a fundamental smart-grid improvement that links supply and demand. From October 2011 to December 2013, the Demand Response Research Center at Lawrence Berkeley National Laboratory, the New York State Energy Research and Development Authority, and partners Honeywell and Akuacom, have conducted a demonstration project enabling Automated Demand Response (Auto-DR) in large commercial buildings located in New York City using Open Automated Demand Response (OpenADR) communication protocols. In particular, this project focuses on demonstrating how the OpenADR platform, enabled by Akuacom, can automate and simplify interactions between buildings and various stakeholders in New York State and enable the automation of customers’ price response to yield bill savings under dynamic pricing. In this paper, the cost control opportunities under day-ahead hourly pricing and Auto-DR control strategies are presented for four demonstration buildings; present the breakdown of Auto-DR enablement costs; summarize the field test results and their load impact; and show potential bill savings by enabling automated price response under Consolidated Edison’s Mandatory Hourly Pricing (MHP) tariff. For one of the sites, the potential bill savings at the site’s current retail rate are shown. Facility managers were given granular equipment-level opt-out capability to ensure full control of the sites during the Auto-DR implementation. The expected bill savings ranged from 1.1% to 8.0% of the total MHP bill. The automation and enablement costs ranged from $70 to $725 per kW shed. The results show that OpenADR can facilitate the automation of price response, deliver savings to the customers and opt-out capability of the implementation retains control of the sites by facility managers.

  12. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William

    2009-07-14

    Disclosed is a method for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise, the transcription being under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells. Initially, a culture media is provided which includes: i) an inducer that causes induction of transcription from said promoter in said bacterial cells; and ii) a metabolite that prevents induction by said inducer, the concentration of said metabolite being adjusted so as to substantially preclude induction by said inducer in the early stages of growth of the bacterial culture, but such that said metabolite is depleted to a level that allows induction by said inducer at a later stage of growth. The culture medium is inoculated with a bacterial inoculum, the inoculum comprising bacterial cells containing cloned DNA, the transcription of which is induced by said inducer. The culture is then incubated under conditions appropriate for growth of the bacterial cells.

  13. Project Final Report: Building a Community Infrastructure for Scalable On-Line Performance Analysis Tools around Open|SpeedShop

    SciTech Connect (OSTI)

    Galarowicz, James

    2014-01-06

    In this project we created a community tool infrastructure for program development tools targeting Petascale class machines and beyond. This includes tools for performance analysis, debugging, and correctness tools, as well as tuning and optimization frameworks. The developed infrastructure provides a comprehensive and extensible set of individual tool building components. We started with the basic elements necessary across all tools in such an infrastructure followed by a set of generic core modules that allow a comprehensive performance analysis at scale. Further, we developed a methodology and workflow that allows others to add or replace modules, to integrate parts into their own tools, or to customize existing solutions. In order to form the core modules, we built on the existing Open|SpeedShop infrastructure and decomposed it into individual modules that match the necessary tool components. At the same time, we addressed the challenges found in performance tools for petascale systems in each module. When assembled, this instantiation of community tool infrastructure provides an enhanced version of Open|SpeedShop, which, while completely different in its architecture, provides scalable performance analysis for petascale applications through a familiar interface. This project also built upon and enhances capabilities and reusability of project partner components as specified in the original project proposal. The overall project teams work over the project funding cycle was focused on several areas of research, which are described in the following sections. The reminder of this report also highlights related work as well as preliminary work that supported the project. In addition to the project partners funded by the Office of Science under this grant, the project team included several collaborators who contribute to the overall design of the envisioned tool infrastructure. In particular, the project team worked closely with the other two DOE NNSA laboratories Los Alamos and Sandia leveraging co-funding for Krell by ASCs Common Computing Environment (CCE) program as laid out in the original proposal. The ASC CCE co-funding, coordinated through LLNL, was for 50% of the total project funding, with the ASC CCE portion of the funding going entirely to Krell, while the ASCR funding itself was split between Krell and the funded partners. This report covers the entire project from both funding sources. Additionally, the team leveraged the expertise of software engineering researchers from Carnegie Mellon University, who specialize in software framework design, in order to achieve a broadly acceptable component framework. The Component Based Tool Framework (CBTF) software has been released to the community. Information related to the project and the released software can be found on the CBTF wiki page at: http://sourceforge.net/p/cbtf/wiki/Home

  14. Case study: An environmental database management system for the auto-body painting process

    SciTech Connect (OSTI)

    Shepard, S.; Souten, D.

    1996-12-31

    The auto-body painting process is subject to numerous environmental regulations, including those directed toward hazardous waste, water pollution prevention, workplace safety, and air pollution. Each environmental regulatory compliance area requires extensive record keeping and reporting of information. Incomplete or untimely reporting and record keeping can result in significant adverse actions by regulatory agencies. Additionally, good data record keeping allows management to have better internal knowledge of plant operations with respect to environmental concerns. The record keeping and reporting prior to the development of the database management system described here were performed using spreadsheets. Although spreadsheets are useful for conducting numerical calculations and plots, they are inflexible to the addition and deletion of different materials (such as paint colors) from year to year. They are clumsy with large amounts of data, and they do not have the querying capabilities of a database. In light of the ever changing reporting requirements to different regulatory agencies, reporting and tracking of emissions data using spreadsheets rapidly becomes extremely difficult. This paper describes the design and implementation of the air pollution portion of an environmental database management system starting with one model year`s worth of spreadsheet data. The design consisted of converting all the relevant data into the database format (including coefficients for calculations within the spreadsheets), formulating a relational model for the data, and designing the user-interface. The program implementation was done in Microsoft Access 2.0. The database design, program features, project successes and difficulties we faced are presented as our example outputs.

  15. Auto-DR and Pre-cooling of Buildings at Tri-City Corporate Center

    SciTech Connect (OSTI)

    Yin, Rongxin; Xu, Peng; Kiliccote, Sila

    2008-11-01

    Over the several past years, Lawrence Berkeley National Laboratory (LBNL) has conducted field tests for different pre-cooling strategies in different commercial buildings within California. The test results indicated that pre-cooling strategies were effective in reducing electric demand in these buildings during peak periods. This project studied how to optimize pre-cooling strategies for eleven buildings in the Tri-City Corporate Center, San Bernardino, California with the assistance of a building energy simulation tool -- the Demand Response Quick Assessment Tool (DRQAT) developed by LBNL's Demand Response Research Center funded by the California Energy Commission's Public Interest Energy Research (PIER) Program. From the simulation results of these eleven buildings, optimal pre-cooling and temperature reset strategies were developed. The study shows that after refining and calibrating initial models with measured data, the accuracy of the models can be greatly improved and the models can be used to predict load reductions for automated demand response (Auto-DR) events. This study summarizes the optimization experience of the procedure to develop and calibrate building models in DRQAT. In order to confirm the actual effect of demand response strategies, the simulation results were compared to the field test data. The results indicated that the optimal demand response strategies worked well for all buildings in the Tri-City Corporate Center. This study also compares DRQAT with other building energy simulation tools (eQUEST and BEST). The comparison indicate that eQUEST and BEST underestimate the actual demand shed of the pre-cooling strategies due to a flaw in DOE2's simulation engine for treating wall thermal mass. DRQAT is a more accurate tool in predicting thermal mass effects of DR events.

  16. Ice plug employed on subsea pipeline bend during repair

    SciTech Connect (OSTI)

    1997-12-22

    The first controlled-temperature ice plug in the bend of an offshore gas trunkline has been carried out for Phillips Petroleum Co. Norway on its Norpipe A.S. platform in the German sector of the North Sea. The procedure was part of a subsea valve repair operation. The ice plug was successfully formed offshore and tested to a differential pressure of 1,450 psi. Repair of two valves required only 5 days during which time gas production was operating at close to 50--60% via the platform bypass, says the service company. The paper discusses the procedure.

  17. Methods to alter levels of a DNA repair protein

    DOE Patents [OSTI]

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-10-17

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  18. Development of quick repairing technique for ceramic burner in hot stove of blast furnace

    SciTech Connect (OSTI)

    Kondo, Atsushi; Doura, Kouji; Nakamura, Hirofumi

    1997-12-31

    Refractories of ceramic burner in hot stoves at Wakayama No. 4 blast furnace were damaged. There are only three hot stoves, so repairing must be done in a short. Therefore, a quick repairing technique for ceramic burners has been developed, and two ceramic burners were repaired in just 48 hours.

  19. Study on Auto-DR and Pre-Cooling of Commercial Buildings with Thermal Mass in California

    SciTech Connect (OSTI)

    Yin, Rongxin; Xu, Peng; Piette, Mary Ann; Kiliccote, Sila

    2010-01-09

    This paper discusses how to optimize pre-cooling strategies for buildings in a hot California climate zone with the Demand Response Quick Assessment Tool (DRQAT), a building energy simulation tool. This paper outlines the procedure used to develop and calibrate DRQAT simulation models, and applies this procedure to eleven field test buildings. The results of a comparison between the measured demand savings during the peak period and the savings predicted by the simulation model indicate that the predicted demand shed match well with measured data for the corresponding auto-demand response (Auto-DR) days. The study shows that the accuracy of the simulation models is greatly improved after calibrating the initial models with measured data. These improved models can be used to predict load reductions for automated demand response events. The simulation results were compared with field test data to confirm the actual effect of demand response strategies. Results indicate that the optimal demand response strategies worked well for most of the buildings tested in this hot climate zone.

  20. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protein Bridges DNA Base and Nucleotide Excision Repair Pathways Print Alkyltransferase proteins (AGT) protect cells from the biological effects of DNA damage caused by the addition of alkyl groups (alkylation). Alkyltransferase-like proteins (ATLs) can do the same, but they lack the reactive cysteine residue that allows the alkyltransferase function, and the mechanism for cell protection has remained unknown. To address this mystery, a British-American team lead by researchers at the Scripps

  1. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protein Bridges DNA Base and Nucleotide Excision Repair Pathways Print Alkyltransferase proteins (AGT) protect cells from the biological effects of DNA damage caused by the addition of alkyl groups (alkylation). Alkyltransferase-like proteins (ATLs) can do the same, but they lack the reactive cysteine residue that allows the alkyltransferase function, and the mechanism for cell protection has remained unknown. To address this mystery, a British-American team lead by researchers at the Scripps

  2. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protein Bridges DNA Base and Nucleotide Excision Repair Pathways Print Alkyltransferase proteins (AGT) protect cells from the biological effects of DNA damage caused by the addition of alkyl groups (alkylation). Alkyltransferase-like proteins (ATLs) can do the same, but they lack the reactive cysteine residue that allows the alkyltransferase function, and the mechanism for cell protection has remained unknown. To address this mystery, a British-American team lead by researchers at the Scripps

  3. Thermostatic/orifice trap reduces fuel, repair costs

    SciTech Connect (OSTI)

    Not Available

    1982-11-01

    This article is an evaluation of a steam trap that combines the continuous drain oriface with a thermostatically controlled trap oriface to efficiently remove condensate from virtually any steam system within its operating limits. This trap effectively reduces fuel and repair costs and has a capacity of 6000 il/hr, handles various pressures up to 600 psig, and operates against back pressures up to 90% of inlet pressure.

  4. adaptation of DNA repair Byrne, Rose T; Klingele, Audrey J; Cabot...

    Office of Scientific and Technical Information (OSTI)

    Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair Byrne, Rose T; Klingele, Audrey J; Cabot, Eric L; Schackwitz, Wendy S; Martin, Jeffrey A;...

  5. One "Cool Tool" That's Helping Repair Your DNA | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    "Cool Tool" That's Helping Repair Your DNA One "Cool Tool" That's Helping Repair Your DNA April 18, 2011 - 1:20pm Addthis Charles Rousseaux Charles Rousseaux Senior Communications Specialist (detailee) What are the key facts? Berkeley Lab's Advanced Light Source produces x-ray light that shines a billion times bright than the sun. Scientists discovered the motor that drives the actual repair of the DNA repair machine called MRN, which is tethered to the rest of the machine in

  6. Brain necrosis after fractionated radiation therapy: Is the halftime for repair longer than we thought?

    SciTech Connect (OSTI)

    Bender, Edward T.

    2012-11-15

    Purpose: To derive a radiobiological model that enables the estimation of brain necrosis and spinal cord myelopathy rates for a variety of fractionation schemes, and to compare repair effects between brain and spinal cord. Methods: Sigmoidal dose response relationships for brain radiation necrosis and spinal cord myelopathy are derived from clinical data using nonlinear regression. Three different repair models are considered and the repair halftimes are included as regression parameters. Results: For radiation necrosis, a repair halftime of 38.1 (range 6.9-76) h is found with monoexponential repair, while for spinal cord myelopathy, a repair halftime of 4.1 (range 0-8) h is found. The best-fit alpha beta ratio is 0.96 (range 0.24-1.73)Conclusions: A radiobiological model that includes repair corrections can describe the clinical data for a variety of fraction sizes, fractionation schedules, and total doses. Modeling suggests a relatively long repair halftime for brain necrosis. This study suggests that the repair halftime for late radiation effects in the brain may be longer than is currently thought. If confirmed in future studies, this may lead to a re-evaluation of radiation fractionation schedules for some CNS diseases, particularly for those diseases where fractionated stereotactic radiation therapy is used.

  7. WPN 12-9: Weatherization Assistance Program Incidental Repair Measure Guidance

    Broader source: Energy.gov [DOE]

    To provide guidance on incidental repair measures (IRM) allowable under the U.S. Department of Energy Weatherization Assistance Program (WAP).

  8. Building America Top Innovations 2013 Profile – Window Replacement, Rehabilitation, & Repair Guide

    SciTech Connect (OSTI)

    none,

    2013-09-01

    In this Top Innovation profile, Building Science Corporation guides contractors through several options for repairing or replacing old windows to improve air sealing and thermal performance.

  9. Blade reliability collaborative : collection of defect, damage and repair data.

    SciTech Connect (OSTI)

    Ashwill, Thomas D.; Ogilvie, Alistair B.; Paquette, Joshua A.

    2013-04-01

    The Blade Reliability Collaborative (BRC) was started by the Wind Energy Technologies Department of Sandia National Laboratories and DOE in 2010 with the goal of gaining insight into planned and unplanned O&M issues associated with wind turbine blades. A significant part of BRC is the Blade Defect, Damage and Repair Survey task, which will gather data from blade manufacturers, service companies, operators and prior studies to determine details about the largest sources of blade unreliability. This report summarizes the initial findings from this work.

  10. Blimp-1{delta}exon7: A naturally occurring Blimp-1 deletion mutant with auto-regulatory potential

    SciTech Connect (OSTI)

    Schmidt, Doris; Nayak, Arnab; Schumann, Julia E.; Schimpl, Anneliese; Berberich, Ingolf Berberich-Siebelt, Friederike

    2008-12-10

    Blimp-1 is a master regulator of terminal B cell differentiation and plays a pivotal role in various developmental processes. In addition to full length Blimp-1, a Blimp-1 mRNA lacking exon 7 (Blimp-1{delta}7) has been described to occur in murine B cells. The activity and function of the mutant mRNA-encoded protein (Blimp-1{delta}7), lacking three crucial zinc fingers necessary for DNA interaction, is completely unknown. Since isoforms of other prdm family proteins affect each other's functions, we wondered whether Blimp-1{delta}7 still plays a role in B cells, independent of direct DNA binding. In this study, we found that Blimp-1{delta}7 is preferentially expressed in naive CD19{sup +} B cells. A fraction of Blimp-1{delta}7 migrates to the nucleus, colocalizes with HDAC2 and is found at sites of repressed chromatin, although it does not bind to the Blimp-1 DNA consensus site. Unexpectedly, Blimp-1 and Blimp-1{delta}7 homodimerize as well as heterodimerize with each other. Ectopic expression of Blimp-1{delta}7 in WEHI 231 cells, a Blimp-1-negative murine lymphoma line, leads to cessation of proliferation and enhancement of apoptosis. Importantly, LPS-induced differentiation is suppressed in the presence of Blimp-1{delta}7. This is in agreement with our finding that Blimp-1{delta}7 interferes with endogenous Blimp-1 expression. Thus, our data suggest an auto-regulatory mechanism of Blimp-1 activation.

  11. New Technologies for Repairing Aging Cables in Nuclear Power Plants

    SciTech Connect (OSTI)

    Simmons, Kevin L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fifield, Leonard S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Westman, Matthew P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-09-11

    The goal of this project is to demonstrate a proof-of-concept for a technique to repair aging cables that have been subjected to degradation associated with long-term thermal and radiation exposure in nuclear power plants. The physical degradation of the aging cables manifests itself primarily as cracking and increased brittleness of the polymeric electrical insulation. Therefore, the proposed cable-repair concept comprises development of techniques to impart a softening agent within the deteriorated polymer insulation jacket so as to regain the ability of the insulation to stretch without failing and possibly to heal existing cracks in the insulation. Our approach is to use commercially available ethylene-propylene rubber (EPR) as the relevant test material, demonstrate the adsorption of chemical treatments in the EPR and quantify changes in resulting physical and mechanical properties. EPR cable samples have been thermally treated in air to produce specimens corresponding to the full range of cable age-performance points from new (>350% elongation at break) to end-of-life (<50% elongation at break). The current focus is on two chemical treatments selected as candidates for restoring age-related cable elasticity loss: a rubber plasticizer and a reactive silane molecule. EPR specimens of 200, 150, 100, and 50% elongation at break have been soaked in the candidate chemical treatments and the kinetics of chemical uptake, measured by change in mass of the samples, has been determined. Mechanical properties as a function of aging and chemical treatment have been measured including ultimate tensile strength, tensile modulus at 50% strain, elongation at break, and storage modulus. Dimensional changes with treatment and changes in glass transition temperature were also investigated. These ongoing experiments are expected to provide insight into the physical-chemical nature of the effect of thermal degradation on EPR rejuvenation limits and to advance novel methods for restoring the ability of degraded EPR to be compliant and resist fracture. The results of this research reveal that absorption of chemical treatments can lower the glass transition temperature and modulus of EPR. Chemical treatments pursued thus far have proven ineffective at restoring EPR strength and elongation at break. Future work will combine the plasticizer modalities found to successfully increase the volume of the EPR, reduce EPR glass transition temperature and reduce EPR modulus with promising chemistries that will repair the damage of the polymer, potentially using the plasticizer as a host for the new chemistry.

  12. Method of tissue repair using a composite material

    DOE Patents [OSTI]

    Hutchens, Stacy A; Woodward, Jonathan; Evans, Barbara R; O'Neill, Hugh M

    2014-03-18

    A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

  13. Method of tissue repair using a composite material

    DOE Patents [OSTI]

    Hutchens, Stacy A.; Woodward, Jonathan; Evans, Barbara R.; O'Neill, Hugh M.

    2016-03-01

    A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

  14. Development and validation of bonded composite doubler repairs for commercial aircraft.

    SciTech Connect (OSTI)

    Roach, Dennis Patrick; Rackow, Kirk A.

    2007-07-01

    A typical aircraft can experience over 2,000 fatigue cycles (cabin pressurizations) and even greater flight hours in a single year. An unavoidable by-product of aircraft use is that crack, impact, and corrosion flaws develop throughout the aircraft's skin and substructure elements. Economic barriers to the purchase of new aircraft have placed even greater demands on efficient and safe repair methods. The use of bonded composite doublers offers the airframe manufacturers and aircraft maintenance facilities a cost effective method to safely extend the lives of their aircraft. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is now possible to bond a single Boron-Epoxy composite doubler to the damaged structure. The FAA's Airworthiness Assurance Center at Sandia National Labs (AANC), Boeing, and Federal Express completed a pilot program to validate and introduce composite doubler repair technology to the U.S. commercial aircraft industry. This project focused on repair of DC-10 fuselage structure and its primary goal was to demonstrate routine use of this repair technology using niche applications that streamline the design-to-installation process. As composite doubler repairs gradually appear in the commercial aircraft arena, successful flight operation data is being accumulated. These commercial aircraft repairs are not only demonstrating the engineering and economic advantages of composite doubler technology but they are also establishing the ability of commercial maintenance depots to safely adopt this repair technique. This report presents the array of engineering activities that were completed in order to make this technology available for widespread commercial aircraft use. Focused laboratory testing was conducted to compliment the field data and to address specific issues regarding damage tolerance and flaw growth in composite doubler repairs. Fatigue and strength tests were performed on a simulated wing repair using a substandard design and a flawed installation. In addition, the new Sol-Gel surface preparation technique was evaluated. Fatigue coupon tests produced Sol-Gel results that could be compared with a large performance database from conventional, riveted repairs. It was demonstrated that not only can composite doublers perform well in severe off-design conditions (low doubler stiffness and presence of defects in doubler installation) but that the Sol-Gel surface preparation technique is easier and quicker to carry out while still producing optimum bonding properties. Nondestructive inspection (NDI) methods were developed so that the potential for disbond and delamination growth could be monitored and crack growth mitigation could be quantified. The NDI methods were validated using full-scale test articles and the FedEx aircraft installations. It was demonstrated that specialized NDI techniques can detect flaws in composite doubler installations before they reach critical size. Probability of Detection studies were integrated into the FedEx training in order to quantify the ability of aircraft maintenance depots to properly monitor these repairs. In addition, Boeing Structural Repair and Nondestructive Testing Manuals were modified to include composite doubler repair and inspection procedures. This report presents the results from the FedEx Pilot Program that involved installation and surveillance of numerous repairs on operating aircraft. Results from critical NDI evaluations are reported in light of damage tolerance assessments for bonded composite doublers. This work has produced significant interest from airlines and aircraft manufacturers. The successful Pilot Program produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. This report discusses both the laboratory data and Pilot Program results from repair installations on operating aircraft to introduce composite doubler repairs into mainstream commercial aircraft use.

  15. Fabrication Flaw Density and Distribution In Repairs to Reactor Pressure Vessel and Piping Welds

    SciTech Connect (OSTI)

    GJ Schuster, FA Simonen, SR Doctor

    2008-04-01

    The Pacific Northwest National Laboratory is developing a generalized fabrication flaw distribution for the population of nuclear reactor pressure vessels and for piping welds in U.S. operating reactors. The purpose of the generalized flaw distribution is to predict component-specific flaw densities. The estimates of fabrication flaws are intended for use in fracture mechanics structural integrity assessments. Structural integrity assessments, such as estimating the frequency of loss-of-coolant accidents, are performed by computer codes that require, as input, accurate estimates of flaw densities. Welds from four different reactor pressure vessels and a collection of archived pipes have been studied to develop empirical estimates of fabrication flaw densities. This report describes the fabrication flaw distribution and characterization in the repair weld metal of vessels and piping. This work indicates that large flaws occur in these repairs. These results show that repair flaws are complex in composition and sometimes include cracks on the ends of the repair cavities. Parametric analysis using an exponential fit is performed on the data. The relevance of construction records is established for describing fabrication processes and product forms. An analysis of these records shows there was a significant change in repair frequency over the years when these components were fabricated. A description of repair flaw morphology is provided with a discussion of fracture mechanics significance. Fabrication flaws in repairs are characterized using optimized-access, high-sensitivity nondestructive ultrasonic testing. Flaw characterizations are then validated by other nondestructive evaluation techniques and complemented by destructive testing.

  16. DNA repair of a single UV photoproduct in a designed nucleosome

    SciTech Connect (OSTI)

    Kosmoskil, Joseph V.; Ackerman, Eric J. ); Smerdon, Michael J.

    2001-08-28

    Eukaryotic DNA repair enzymes must interact with the architectural hierarchy of chromatin. The challenge of finding damaged DNA complexed with histone proteins in nucleosomes is complicated by the need to maintain local chromatin structures involved in regulating other DNA processing events. The heterogeneity of lesions induced by DNA-damaging agents has led us to design homogeneously damaged substrates to directly compare repair of naked DNA with that of nucleosomes. Here we report that nucleotide excision repair in Xenopus nuclear extracts can effectively repair a single UV radiation photoproduct located 5 bases from the dyad center of a positioned nucleosome, although the nucleosome is repaired at about half the rate at which the naked DNA fragment is. Extract repair within the nucleosome is > 50-fold more rapid than either enzymatic photoreversal or endonuclease cleavage of the lesion in vitro. Furthermore, nucleosome formation occurs (after repair) only on damaged naked DNA ( 165-bp fragments) during a 1-h incubation in these extracts, even in the presence of a large excess of undamaged DNA. This is an example of selective nucleosome assembly by Xenopus nuclear extracts on a short linear DNA fragment containing a DNA lesion.

  17. CDK1 enhances mitochondrial bioenergetics for radiation-induced DNA repair

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Qin, Lili; Fan, Ming; Candas, Demet; Jiang, Guochun; Papadopoulos, Stelios; Tian, Lin; Woloschak, Gayle; Grdina, David J.; Li, Jian  Jian

    2015-12-06

    Nuclear DNA repair capacity is a critical determinant of cell fate under genotoxic stress conditions. DNA repair is a well-defined energy-consuming process. However, it is unclear how DNA repair is fueled and whether mitochondrial energy production contributes to nuclear DNA repair. Here, we report a dynamic enhancement of oxygen consumption and mitochondrial ATP generation in irradiated normal cells, paralleled with increased mitochondrial relocation of the cell-cycle kinase CDK1 and nuclear DNA repair. The basal and radiation-induced mitochondrial ATP generation is reduced significantly in cells harboring CDK1 phosphorylation-deficient mutant complex I subunits. Similarly, mitochondrial ATP generation and nuclear DNA repair aremore »also compromised severely in cells harboring mitochondrially targeted, kinase-deficient CDK1. These findings demonstrate a mechanism governing the communication between mitochondria and the nucleus by which CDK1 boosts mitochondrial bioenergetics to meet the increased cellular fuel demand for DNA repair and cell survival under genotoxic stress conditions.« less

  18. Effect of multiple repairs in girth welds of pipelines on the mechanical properties

    SciTech Connect (OSTI)

    Vega, O.E.; Hallen, J.M.; Villagomez, A.

    2008-10-15

    This work presents the results of multiple weld repairs in the same area in seamless API X-52 microalloyed steel pipe. Four conditions of shielded metal arc welding repairs and one as-welded specimen of the girth weld were characterized to determine changes in the microstructure, grain size in the heat affected zone, and to evaluate their effect on the mechanical properties of the weld joints. The mechanical properties by means of tension tests, Charpy-V impact resistance and Vickers hardness of the welds were analyzed. The results indicate that significant changes are not generated in the microstructural constituents of the heat affected zone. Grain growth in the heat affected zone at the specimen mid-thickness with the number of repairs was observed. Tensile strength of the weld joints meets the requirement of the API 1104 standard even after the fourth weld repair. Significant reduction in Charpy-V impact resistance with the number of weld repairs was found when the notch location was in the intersection of the fusion line with the specimen mid-thickness. A significant increase in the Vickers hardness of the heat affected zone occurred after the first repair and a gradual decrease in the Vickers hardness occurred as the number of repairs increases.

  19. Microsoft PowerPoint - Bull Shoals U1 repair MSB edit 3.ppt

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bull Shoals Unit 1 161kV Switchyard Feeder Repair Bull Shoals Unit 1 161kV Bull Shoals Unit 1 161kV Switchyard Feeder Repair Switchyard Feeder Repair Mark Dixson Little Rock District US Army Corps US Army Corps of Engineers of Engineers ® ® One Corps Serving The Army and the Nation * Original Equipment - 52 years old. * Unit 1 Oil filled cable pothead failed and exploded on Sept 6 2006. * Resulting fire and fire suppression damaged oil insulated cable system * Minor damage to power plant.

  20. Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec.

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    1-20, 2006 | Department of Energy Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Docket No. EO-05-01. Regarding the planned line outage, scheduled for Feb. 20 through Mar. 6, I am requesting that the residents near the plant be moved for the duration of the outage to protect their health. PDF icon Emailed Comments of Elizabeth Chimento RE: Pepco Scheduled Line Repair

  1. RCRA Facility Investigation/Remedial Investigation Report with Baseline Risk Assessment for the Central Shops Burning/Rubble Pit (631-6G), Volume 1 Final

    SciTech Connect (OSTI)

    1996-04-01

    The Burning/Rubble Pits at the Savannah River Site were usually shallow excavations approximately 3 to 4 meters in depth. Operations at the pits consisted of collecting waste on a continuous basis and burning on a monthly basis. The Central Shops Burning/Rubble Pit 631- 6G (BRP6G) was constructed in 1951 as an unlined earthen pit in surficial sediments for disposal of paper, lumber, cans and empty galvanized steel drums. The unit may have received other materials such as plastics, rubber, rags, cardboard, oil, degreasers, or drummed solvents. The BRP6G was operated from 1951 until 1955. After disposal activities ceased, the area was covered with soil. Hazardous substances, if present, may have migrated into the surrounding soil and/or groundwater. Because of this possibility, the United States Environmental Protection Agency (EPA) has designated the BRP6G as a Solid Waste Management Unit (SWMU) subject to the Resource Conservation Recovery Act/Comprehensive Environmental Response, Compensation and Liability Act (RCRA/CERCLA) process.

  2. Community-Minded Interns at Savannah River Site Help Area Residents in Need with Home Repairs

    Broader source: Energy.gov [DOE]

    AIKEN, S.C. – More than two dozen college interns who worked at the Savannah River Site (SRS) this summer joined other volunteers and headed into area neighborhoods to help people in need with home repairs.

  3. Review of Maintenance and Repair Times for Components in Technological Facilities

    SciTech Connect (OSTI)

    L. C. Cadwallader

    2012-11-01

    This report is a compilation of some unique component repair time data and it also presents citations of more extensive reports where lists of repair times can be found. This collection of information should support analysts who seek to quantify maintainability and availability of high technology and nuclear energy production systems. While there are newer sources of repair time information, most, if not all, of the newer sources are proprietary and cannot be shared. This report offers data that, while older, is openly accessible and can serve as reasonable estimates of repair times, at least for initial studies. Some times were found for maintenance times in radiation environments, and some guidance for multiplicative factors to use to account for work in contamination areas.

  4. Inducible error-prone repair in B. subtilis. Final report, September 1, 1979-June 30, 1981

    SciTech Connect (OSTI)

    Yasbin, R. E.

    1981-06-01

    The research performed under this contract has been concentrated on the relationship between inducible DNA repair systems, mutagenesis and the competent state in the gram positive bacterium Bacillus subtilis. The following results have been obtained from this research: (1) competent Bacillus subtilis cells have been developed into a sensitive tester system for carcinogens; (2) competent B. subtilis cells have an efficient excision-repair system, however, this system will not function on bacteriophage DNA taken into the cell via the process of transfection; (3) DNA polymerase III is essential in the mechanism of the process of W-reactivation; (4) B. subtilis strains cured of their defective prophages have been isolated and are now being developed for gene cloning systems; (5) protoplasts of B. subtilis have been shown capable of acquiring DNA repair enzymes (i.e., enzyme therapy); and (6) a plasmid was characterized which enhanced inducible error-prone repair in a gram positive organism.

  5. Tiny Terminators: New Micro-Robots Assemble, Repair Themselves and Are Surprisingly Strong

    Broader source: Energy.gov [DOE]

    Tiny robots that can assemble and repair themselves? Watch a video of Argonne National Laboratory's micro-robots that easily perform tasks that can challenge other robots, including moving objects that are larger than themselves.

  6. In situ repair of a failed compression fitting

    DOE Patents [OSTI]

    Wolbert, Ronald R.; Jandrasits, Walter G.

    1986-01-01

    A method and apparatus for the in situ repair of a failed compression fitg is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  7. In situ repair of a failed compression fitting

    DOE Patents [OSTI]

    Wolbert, R.R.; Jandrasits, W.G.

    1985-08-05

    A method and apparatus for the in situ repair of a failed compression fitting is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  8. From Autos to Accelerators

    Broader source: Energy.gov [DOE]

    In a town haunted by the remains of fallen automobile plants, some companies are hiring workers to put their car-manufacturing skills toward building particle accelerators.

  9. RESTORING A DAMAGED 16-YEAR -OLD INSULATING POLYMER CONCRETE DIKE OVERLAY: REPAIR MATERIALS AND TECHNOLOGIES.

    SciTech Connect (OSTI)

    SUGAMA,T.

    2007-01-01

    The objective of this program was to design and formulate organic polymer-based material systems suitable for repairing and restoring the overlay panels of insulating lightweight polymer concrete (ILPC) from the concrete floor and slope wall of a dike at KeySpan liquefied natural gas (LNG) facility in Greenpoint, Brooklyn, NY, just over sixteen years ago. It also included undertaking a small-scale field demonstration to ensure that the commercial repairing technologies were applicable to the designed and formulated materials.

  10. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

    Office of Scientific and Technical Information (OSTI)

    (Journal Article) | SciTech Connect SciTech Connect Search Results Journal Article: Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1 Citation Details In-Document Search Title: Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1 Authors: Wang, Renjing ; Persky, Nicole S. ; Yoo, Barney ; Ouerfelli, Ouathek ; Smogorzewska, Agata ; Elledge, Stephen J. ; Pavletich, Nikola P. [1] ; MSKCC) [2] ; Rockefeller) [2] + Show Author Affiliations

  11. Method to repair localized amplitude defects in a EUV lithography mask blank

    DOE Patents [OSTI]

    Stearns, Daniel G.; Sweeney, Donald W.; Mirkarimi, Paul B.; Chapman, Henry N.

    2005-11-22

    A method and apparatus are provided for the repair of an amplitude defect in a multilayer coating. A significant number of layers underneath the amplitude defect are undamaged. The repair technique restores the local reflectivity of the coating by physically removing the defect and leaving a wide, shallow crater that exposes the underlying intact layers. The particle, pit or scratch is first removed the remaining damaged region is etched away without disturbing the intact underlying layers.

  12. Solgel auto-combustion synthesis of PVP/CoFe{sub 2}O{sub 4} nanocomposite and its magnetic characterization

    SciTech Connect (OSTI)

    Kurtan, U.; Topkaya, R.; Baykal, A.

    2013-11-15

    Graphical abstract: - Highlights: The Poly(vinyl pyrrolidone) (PVP) was used as a surface capping agent. PVP/CoFe{sub 2}O{sub 4} nanocomposite was synthesized by a sol-gel auto-combustion method. The existence of the spin-disordered surface layer was established. - Abstract: Poly(vinyl pyrrolidone)/CoFe{sub 2}O{sub 4} nanocomposite has been fabricated by a solgel auto-combustion method. Poly(vinyl pyrrolidone) was used as a reducing agent as well as a surface capping agent to prevent particle aggregation and stabilize the particles. The average crystallite size estimated from X-ray line profile fitting was found to be 20 7 nm. The high field irreversibility and unsaturated magnetization behaviours indicate the presence of the coreshell structure in the sample. The exchange bias effect observed at 10 K suggests the existence of the magnetically aligned core surrounded by spin-disordered surface layer. The reduced remanent magnetization value of 0.6 at 10 K (higher than the theoretical value of 0.5) shows the PVP/CoFe{sub 2}O{sub 4} nanocomposite to have cubic magnetocrystalline anisotropy according to the StonerWohlfarth model.

  13. Relocation and repair of the National Geotechnical Centrifuge. Final report

    SciTech Connect (OSTI)

    Cheney, J.A.

    1994-10-01

    In January of 1984, the large geotechnical centrifuge located at NASA Ames Research Center, was in the first stages of operational checkout when the main thrust bearing of the large D.C. drive motor failed. After many months of investigation and proposals for repair of the facility, it became evident that it would be far more advantageous to the engineering community to remove those components of the centrifuge that were undamaged to the Davis campus and replace the drive system completely. The large centrifuge had cost over 2 million dollars to build, and it would have been irresponsible to simply scrap it. Recognizing this fact, funds were solicited and received from various sources, and Beam Engineering Inc. was contracted to design and construct the centrifuge at its new location. The University of California contributed a quarter of a million dollars and Tyndall Air Force Base, through Los Alamos National Laboratory, contributed $140,000. There were funds also contributed by LANL, LLNL, US Navy and NSF. The first stage in the phased development of the newly located centrifuge is nearing completion, which prompts the writing of this report. By the time that this report reaches the reader the first runs of the centrifuge will have been completed. The present report describes the present capability of the centrifuge and the plans for upgrading as time goes on. Several pilot studies were carried out. The experiments involved (1) the effects of nearby explosions on buried thin walled containers and (2) the advection and dispersion of toxic waste water through soils.

  14. INTERNAL REPAIR OF GAS PIPLINES SURVEY OF OPERATOR EXPERIENCE AND INDUSTRY NEEDS REPORT

    SciTech Connect (OSTI)

    Ian D. Harris

    2003-09-01

    A repair method that can be applied from the inside of a gas transmission pipeline (i.e., a trenchless repair) is an attractive alternative to conventional repair methods since the need to excavate the pipeline is precluded. This is particularly true for pipelines in environmentally sensitive and highly populated areas. The objectives of the project are to evaluate, develop, demonstrate, and validate internal repair methods for pipelines; develop a functional specification for an internal pipeline repair system; and prepare a recommended practice for internal repair of pipelines. The purpose of this survey is to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. A total of fifty-six surveys were sent to pipeline operators. A total of twenty completed surveys were returned, representing a 36% response rate, which is considered very good given the fact that tailored surveys are known in the marketing industry to seldom attract more than a 10% response rate. The twenty survey responses produced the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water (e.g., lakes and swamps) in difficult soil conditions, under highways, under congested intersections, and under railway crossings. All these areas tend to be very difficult and very costly if, and where, conventional excavated repairs may be currently used. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem in a water/river crossing. (3) The typical travel distances required can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). In concept, these groups require pig-based systems; despooled umbilical systems could be considered for the first two groups. For the last group a self-propelled system with an onboard self-contained power and welding system is required. (4) Pipe size range requirements range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.) in diameter. The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.) diameter, with 95% using 558.8 mm (22 in.) diameter pipe.

  15. Development of bonded composite doublers for the repair of oil recovery equipment.

    SciTech Connect (OSTI)

    Roach, David W.; Rackow, Kirk A.

    2005-06-01

    An unavoidable by-product of a metallic structure's use is the appearance of crack and corrosion flaws. Economic barriers to the replacement of these structures have created an aging infrastructure and placed even greater demands on efficient and safe repair methods. In the past decade, an advanced composite repair technology has made great strides in commercial aviation use. Extensive testing and analysis, through joint programs between the Sandia Labs FAA Airworthiness Assurance Center and the aviation industry, have proven that composite materials can be used to repair damaged aluminum structure. Successful pilot programs have produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. With this foundation in place, this effort is adapting bonded composite repair technology to civil structures. The use of bonded composite doublers has the potential to correct the difficulties associated with current repair techniques and the ability to be applied where there are no rehabilitation options. It promises to be cost-effective with minimal disruption to the users of the structure. This report concludes a study into the application of composite patches on thick steel structures typically used in mining operations. Extreme fatigue, temperature, erosive, and corrosive environments induce an array of equipment damage. The current weld repair techniques for these structures provide a fatigue life that is inferior to that of the original plate. Subsequent cracking must be revisited on a regular basis. The use of composite doublers, which do not have brittle fracture problems such as those inherent in welds, can help extend the structure's fatigue life and reduce the equipment downtime. Two of the main issues for adapting aircraft composite repairs to civil applications are developing an installation technique for carbon steel and accommodating large repairs on extremely thick structures. This study developed and proved an optimum field installation process using specific mechanical and chemical surface preparation techniques coupled with unique, in-situ heating methods. In addition, a comprehensive performance assessment of composite doubler repairs was completed to establish the viability of this technology for large, steel structures. The factors influencing the durability of composite patches in severe field environments were evaluated along with related laminate design issues.

  16. Strategy making and power in environmental assessments. Lessons from the establishment of an out-of-town shopping centre in Vaesteras, Sweden

    SciTech Connect (OSTI)

    Isaksson, Karolina; Storbjoerk, Sofie

    2012-04-15

    This paper seeks to provide deeper insights into how EA ineffectiveness is produced in land use planning practice. This is explored in a study of local development planning in the city of Vaesteras, Sweden. The case in question is the development of a large out-of-town shopping centre, propelled by the establishment of a new IKEA furniture store. The Healey (2007) framework of planning as strategy making is applied as an analytical framework, together with a focus on power-knowledge relations. In the analysis, we identify a range of mechanisms that produced ineffectiveness by limiting the role of environmental knowledge throughout the planning process. The specific mechanisms we identified were related to the overall consensus perspective in local development strategies and plans, a lack of concretisation and integration of various policies and strategies, a range of exclusion mechanisms and an overall focus on mitigation and benefits of the process in question. In practice, these mechanisms were closely intertwined. Our main conclusion is, consequently, that increased effectiveness of EA would require fundamental transformation of the norms, frameworks and routines that implicitly and explicitly guide land use planning in practice. - Highlights: Black-Right-Pointing-Pointer We analyse how EA-ineffectiveness is produced in land use planning practice. Black-Right-Pointing-Pointer Several mechanisms produce EA-ineffectiveness throughout the whole planning process. Black-Right-Pointing-Pointer These mechanisms are often closely intertwined and mutually reinforcing each other. Black-Right-Pointing-Pointer Enhancing EA-effectiveness requires a fundamental shift of the norms, frameworks and routines shaping planning practice.

  17. Revised Finding of No Significant Impact for Expansion and Operation of the Central Shops Borrow Pit at the Savannah River Site (10/29/03)

    SciTech Connect (OSTI)

    N /A

    2003-10-29

    The Department of Energy (DOE) prepared an environmental assessment (EA) (DOE/EA-1194) in 1997 for the expansion and operation of the existing Central Shops Borrow Pit (i.e., SRS Facility 632-G) at the Savannah River Site (SRS), located near Aiken, South Carolina. This EA was prepared in accordance with the National Environmental Policy Act (NEPA) of 1969, as amended; the requirements of the Council on Environmental Quality Regulations for Implementing NEPA (40 CFR 15400-1508); and the DOE Regulations for Implementing NEPA (10 CFR 1021). Based on the analyses in the EA, DOE determined that the action was not a major Federal action significantly affecting the quality of the human environment within the meaning of NEPA. Therefore, the preparation of an environmental impact statement (EIS) was not required, and DOE issued a Finding of No Significant Impact (FONSI) dated March 13, 1997. In an effort to provide the site with cost-effective future landfill capacity for construction and demolition (C&D) debris/structural fill, DOE is considering redefining the closure of the 632-G facility to encompass the permitted disposal of inert C&D debris into the excavation areas, which would then be closed as per regulatory requirements. Based on the existing infrastructure at the 632-G facility that would support a permitted Part III C&D Landfill, DOE has concluded that the environmental impacts of the proposed use of the excavated portions of this facility as an inert debris landfill is not a major Federal action significantly affecting the quality of the human environment within the meaning of NEPA. Therefore, the preparation of an EIS is not required, and DOE is issuing this revised FONSI.

  18. DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage

    SciTech Connect (OSTI)

    Marchetti, Francesco; Marchetti, Francesco; Wryobek, Andrew J

    2008-02-21

    The post-meiotic phase of mouse spermatogenesis (spermiogenesis) is very sensitive to the genomic effects of environmental mutagens because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. We hypothesized that repeated exposures to mutagens during this repair-deficient phase result in the accumulation of heritable genomic damage in mouse sperm that leads to chromosomal aberrations in zygotes after fertilization. We used a combination of single or fractionated exposures to diepoxybutane (DEB), a component of tobacco smoke, to investigate how differential DNA repair efficiencies during the three weeks of spermiogenesis affected the accumulation of DEB-induced heritable damage in early spermatids (21-15 days before fertilization, dbf), late spermatids (14-8 dbf) and sperm (7- 1 dbf). Analysis of chromosomalaberrations in zygotic metaphases using PAINT/DAPI showed that late spermatids and sperm are unable to repair DEB-induced DNA damage as demonstrated by significant increases (P<0.001) in the frequencies of zygotes with chromosomal aberrations. Comparisons between single and fractionated exposures suggested that the DNA repair-deficient window during late spermiogenesis may be less than two weeks in the mouse and that during this repair-deficient window there is accumulation of DNA damage in sperm. Finally, the dose-response study in sperm indicated a linear response for both single and repeated exposures. These findings show that the differential DNA repair capacity of post-meioitic male germ cells has a major impact on the risk of paternally transmitted heritable damage and suggest that chronic exposures that may occur in the weeks prior to fertilization because of occupational or lifestyle factors (i.e, smoking) can lead to an accumulation of genetic damage in sperm and result in heritable chromosomal aberrations of paternal origin.

  19. DNA Repair Decline During Mouse Spermiogenesis Results in the Accumulation of Heritable DNA Damage

    SciTech Connect (OSTI)

    Marchetti, Francesco; Marchetti, Francesco; Wyrobek, Andrew J.

    2007-12-01

    The post-meiotic phase of mouse spermatogenesis (spermiogenesis) is very sensitive to the genomic effects of environmental mutagens because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. We hypothesized that repeated exposures to mutagens during this repair-deficient phase result in the accumulation of heritable genomic damage in mouse sperm that leads to chromosomal aberrations in zygotes after fertilization. We used a combination of single or fractionated exposures to diepoxybutane (DEB), a component of tobacco smoke, to investigate how differential DNA repair efficiencies during the three weeks of spermiogenesis affected the accumulation of DEB-induced heritable damage in early spermatids (21-15 days before fertilization, dbf), late spermatids (14-8 dbf) and sperm (7-1 dbf). Analysis of chromosomal aberrations in zygotic metaphases using PAINT/DAPI showed that late spermatids and sperm are unable to repair DEB-induced DNA damage as demonstrated by significant increases (P<0.001) in the frequencies of zygotes with chromosomal aberrations. Comparisons between single and fractionated exposures suggested that the DNA repair-deficient window during late spermiogenesis may be less than two weeks in the mouse and that during this repair-deficient window there is accumulation of DNA damage in sperm. Finally, the dose-response study in sperm indicated a linear response for both single and repeated exposures. These findings show that the differential DNA repair capacity of post-meioitic male germ cells has a major impact on the risk of paternally transmitted heritable damage and suggest that chronic exposures that may occur in the weeks prior to fertilization because of occupational or lifestyle factors (i.e, smoking) can lead to an accumulation of genetic damage in sperm and result in heritable chromosomal aberrations of paternal origin.

  20. WHERE MULTIFUNCTIONAL DNA REPAIR PROTEINS MEET: MAPPING THE INTERACTION DOMAINS BETWEEN XPG AND WRN

    SciTech Connect (OSTI)

    Rangaraj, K.; Cooper, P.K.; Trego, K.S.

    2009-01-01

    The rapid recognition and repair of DNA damage is essential for the maintenance of genomic integrity and cellular survival. Multiple complex and interconnected DNA damage responses exist within cells to preserve the human genome, and these repair pathways are carried out by a specifi c interplay of protein-protein interactions. Thus a failure in the coordination of these processes, perhaps brought about by a breakdown in any one multifunctional repair protein, can lead to genomic instability, developmental and immunological abnormalities, cancer and premature aging. This study demonstrates a novel interaction between two such repair proteins, Xeroderma pigmentosum group G protein (XPG) and Werner syndrome helicase (WRN), that are both highly pleiotropic and associated with inherited genetic disorders when mutated. XPG is a structure-specifi c endonuclease required for the repair of UV-damaged DNA by nucleotide excision repair (NER), and mutations in XPG result in the diseases Xeroderma pigmentosum (XP) and Cockayne syndrome (CS). A loss of XPG incision activity results in XP, whereas a loss of non-enzymatic function(s) of XPG causes CS. WRN is a multifunctional protein involved in double-strand break repair (DSBR), and consists of 3’–5’ DNA-dependent helicase, 3’–5’ exonuclease, and single-strand DNA annealing activities. Nonfunctional WRN protein leads to Werner syndrome, a premature aging disorder with increased cancer incidence. Far Western analysis was used to map the interacting domains between XPG and WRN by denaturing gel electrophoresis, which separated purifi ed full length and recombinant XPG and WRN deletion constructs, based primarily upon the length of each polypeptide. Specifi c interacting domains were visualized when probed with the secondary protein of interest which was then detected by traditional Western analysis using the antibody of the secondary protein. The interaction between XPG and WRN was mapped to the C-terminal region of XPG as well as the C-terminal region of WRN. The physical interaction between XPG and WRN links NER, (made evident by the disease XP) with DSBR, which imparts additional knowledge of the overlapping nature of these two proteins and the previously distinct DNA repair pathways they are associated with. Since genomic integrity is constantly threatened by both endogenous and exogenous (internal and external) damage, understanding the roles of these proteins in coordinating DNA repair processes with replication will signifi cantly further understanding how defects instigate physiological consequences in response to various DNA damaging sources. This ultimately contributes to our understanding of cancer and premature aging.

  1. Fabrication Flaw Density and Distribution in the Repairs of Reactor Pressure Vessels

    SciTech Connect (OSTI)

    Schuster, George J.; Doctor, Steven R.; Simonen, Fredric A.

    2006-02-15

    The Pacific Northwest National Laboratory (PNNL) is developing a generalized flaw size and density distribution for the population of U.S. reactor pressure vessels (RPVs). The purpose of the generalized flaw distribution is to predict vessel specific flaw rates for use in probabilistic fracture mechanics calculations that estimate vessel failure probability. Considerable progress has been made on the construction of an engineering data base of fabrication flaws in U.S. nuclear RPVs. The fabrication processes and product forms used to construct U.S. RPVs are represented in the data base. A validation methodology has been developed for characterizing the flaws for size, shape, orientation, and composition. The relevance of construction records has been established for describing fabrication processes and product forms. The fabrication flaws were detected in material removed from cancelled nuclear power plants using high sensitivity nondestructive ultrasonic testing, and validated by other nondestructive evaluation (NDE) techniques, and complemented by destructive testing. This paper describes research that has generated data on welding flaws, which indicated that the largest flaws occur in weld repairs. Recent research results confirm that repair flaws are complex in composition and may include cracks on the repair ends. Section III of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code for nuclear power plant components requires radiographic examinations (RT) of welds and requires repairs for RT indications that exceed code acceptable sizes. PNNL has previously obtained the complete construction records for two RPVs. Analysis of these records show a significant change in repair frequency.

  2. Equipment | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Machine Shop

  3. Evaluation of bisphenol E cyanate ester for the resin-injection repair of advanced composites

    SciTech Connect (OSTI)

    Wilber Yaote Lio

    2009-12-19

    This thesis is a compilation of a general introduction and literature review that ties together the subsequent chapters which consist of two journal articles that have yet to be submitted for publication. The overall topic relates to the evaluation and application of a new class of cyanate ester resin with unique properties that lend it applicable to use as a resin for injection repair of high glass transition temperature polymer matrix composites. The first article (Chapter 2) details the evaluation and optimization of adhesive properties of this cyanate ester and alumina nanocomposites under different conditions. The second article (Chapter 3) describes the development and evaluation of an injection repair system for repairing delaminations in polymer matrix composites.

  4. Automatic coke oven heating control system at Burns Harbor for normal and repair operation

    SciTech Connect (OSTI)

    Battle, E.T.; Chen, K.L.

    1997-12-31

    An automatic heating control system for coke oven batteries was developed in 1985 for the Burns Harbor No. 1 battery and reported in the 1989 Ironmaking Conference Proceedings. The original system was designed to maintain a target coke temperature at a given production level under normal operating conditions. Since 1989, enhancements have been made to this control system so that it can also control the battery heating when the battery is under repair. The new control system has improved heating control capability because it adjusts the heat input to the battery in response to anticipated changes in the production schedule. During a recent repair of this 82 oven battery, the pushing schedule changed from 102 ovens/day to 88 ovens/day, then back to 102 ovens/day, then to 107 ovens/day. During this repair, the control system was able to maintain the coke temperature average standard deviation at 44 F, with a maximum 75 F.

  5. Alternatives Analysis Amchitka Island Mud Pit Cap Repair, Amchitka, Alaska January 2016

    SciTech Connect (OSTI)

    Darr, Paul S.

    2016-01-01

    The U.S. Department of Energy (DOE) Office of Legacy Management (LM) manages the Nevada Offsites program, which includes a series of reclaimed drilling mud impoundments on Amchitka Island, Alaska (Figure 1). Navarro Research and Engineering, Inc. is the Legacy Management Support contractor (the Contractor) for LM. The Contractor has procured Tetra Tech, Inc. to provide engineering support to the Amchitka mud pit reclamation project. The mud pit caps were damaged during a 7.9-magnitude earthquake that occurred in 2014. The goals of the current project are to investigate conditions at the mud pit impoundments, identify feasible alternatives for repair of the cover systems and the contents, and estimate relative costs of repair alternatives. This report presents descriptions of the sites and past investigations, existing conditions, summaries of various repair/mitigation alternatives, and direct, unburdened, order-of-magnitude (-15% to +50%) associated costs.

  6. A survey of repair practices for nuclear power plant containment metallic pressure boundaries

    SciTech Connect (OSTI)

    Oland, C.B.; Naus, D.J.

    1998-05-01

    The Nuclear Regulatory Commission has initiated a program at the Oak Ridge National Laboratory to provide assistance in their assessment of the effects of potential degradation on the structural integrity and leaktightness of metal containment vessels and steel liners of concrete containments in nuclear power plants. One of the program objectives is to identify repair practices for restoring metallic containment pressure boundary components that have been damaged or degraded in service. This report presents issues associated with inservice condition assessments and continued service evaluations and identifies the rules and requirements for the repair and replacement of nonconforming containment pressure boundary components by welding or metal removal. Discussion topics include base and welding materials, welding procedure and performance qualifications, inspection techniques, testing methods, acceptance criteria, and documentation requirements necessary for making acceptable repairs and replacements so that the plant can be returned to a safe operating condition.

  7. Effect of Zn doping on structural, magnetic and dielectric properties of LaFeO{sub 3} synthesized through sol–gel auto-combustion process

    SciTech Connect (OSTI)

    Bhat, Irshad; Husain, Shahid; Khan, Wasi; Patil, S.I.

    2013-11-15

    Graphical abstract: - Highlights: • We have synthesized the samples of LaFe{sub 1−x}Zn{sub x}O{sub 3} (0 ≤ x ≤ 0.3) using sol–gel auto-combustion process. • The doping of Zn{sup 2+} hugely enhances the dielectric constant (ε′) and it shows a colossal value. • The parent compound LaFeO{sub 3} does not show any relaxation peak, but the substitution of Zn at Fe{sup 3+} site brings the relaxation in the system. • The system shows a peak behavior thereby giving the Debye like dipolar relaxation response. - Abstract: We have studied the structural and dielectric properties of nano-crystalline LaFe{sub 1−x}Zn{sub x}O{sub 3} (0 ≤ x ≤ 0.3) pervoskite samples synthesized through sol–gel auto-combustion technique. X-ray diffraction and FTIR spectroscopy are used to confirm the single phase characteristics. Microstructural features are investigated using scanning electron microscope and compositional analysis is performed through energy dispersive spectroscopy. The average grain sizes, calculated from the Scherrer formula, lie in the range below 30 nm. The hysteresis (M-H) curves display a weak magnetic order and a shift in the hysteresis loops. Dielectric response has been discussed, in the framework of “universal dielectric response” model. The value of dielectric constant (ε′) increases drastically on Zn doping. The dielectric loss factor (ε″) shows Debye like dipolar relaxation behavior. The observed peaks in loss factor (ε″) are attributed to the fact that a strong correlation between the conduction mechanism and the dielectric behavior exists in ferrites.

  8. Bosh repairs No. 3 blast furnace, Edgar Thomson Plant Mon Valley Works

    SciTech Connect (OSTI)

    Stoupis, M.G.

    1993-01-01

    The paper describes in detail the steps taken from quenching to dry out of the furnace to repair the bosh area of the No.3 blast furnace. Inspection of the area revealed that there was no brick anywhere in the bosh. Brick in the tuyere breast area had been peeled back to reveal the steel plate, and descaling revealed 14 pipes fully exposed. None were leaking, but one seemed badly deteriorated. Conventional repairs could not take place before the scheduled blow-in. Installation of coolers were instead tried.

  9. Remote reactor repair: GTA (gas tungsten Arc) weld cracking caused by entrapped helium

    SciTech Connect (OSTI)

    Kanne, W.R. Jr.

    1988-01-01

    A repair patch was welded to the wall of a nuclear reactor tank using remotely controlled thirty-foot long robot arms. Further repair was halted when gas tungsten arc (GTA) welds joining type 304L stainless steel patches to the 304 stainless steel wall developed toe cracks in the heat-affected zone (HAZ). The role of helium in cracking was investigated using material with entrapped helium from tritium decay. As a result of this investigation, and of an extensive array of diagnostic tests performed on reactor tank wall material, helium embrittlement was shown to be the cause of the toe cracks.

  10. Hot repair of ceramic burner on hot blast stoves at USS/Kobe`s {number_sign}3 blast furnace

    SciTech Connect (OSTI)

    Bernarding, T.F.; Chemorov, M.; Shimono, S.; Phillips, G.R.

    1997-12-31

    During the 1992 reline of the No. 3 blast furnace, three new stoves were constructed. The design of the stoves, equipped with internal ceramic burners, was for providing a hot blast temperature of 2,000 F at a wind rate of 140,000 SCFM. After 3 years the performance had deteriorated so the burners were cleaned. When a second cleaning did not improve the performance of No. 3 blast furnace, it was decided to repair the refractory while still hot. The paper describes the hot repair procedures, taking a stove off for repairs, maintenance heat up during repairs, two stove operation, stove commissioning, repair of a ceramic burner, and wet gas prevention.

  11. Shopping for outage management systems

    SciTech Connect (OSTI)

    Chou, Y.C.; Konneker, L.K.; Watkins, T.R.

    1995-12-31

    Customer service is becoming increasingly important to electric utilities. Outage management is an important part of customer service. Good outage management means quickly responding to outages and keeping customers informed about outages. Each outage equals lost customer satisfaction and lost revenue. Outage management is increasingly important because of new competition among utilities for customers, pressure from regulators, and internal pressure to cut costs. The market has several existing software products for outage management. How does a utility judge whether these products satisfy their specific needs? Technology is changing rapidly to support outage management. Which technology is proven and cost-effective? The purpose of this paper is to outline the procedure for evaluating outage management systems, and to discuss the key features to look for. It also gives our opinion of the features that represent state of the art. This paper will not discuss specific products or list vendors names.

  12. DNA repair efficiency in germ cells and early mouse embryos and consequences for radiation-induced transgenerational genomic damage

    SciTech Connect (OSTI)

    Marchetti, Francesco; Wyrobek, Andrew J.

    2009-01-18

    Exposure to ionizing radiation and other environmental agents can affect the genomic integrity of germ cells and induce adverse health effects in the progeny. Efficient DNA repair during gametogenesis and the early embryonic cycles after fertilization is critical for preventing transmission of DNA damage to the progeny and relies on maternal factors stored in the egg before fertilization. The ability of the maternal repair machinery to repair DNA damage in both parental genomes in the fertilizing egg is especially crucial for the fertilizing male genome that has not experienced a DNA repair-competent cellular environment for several weeks prior to fertilization. During the DNA repair-deficient period of spermatogenesis, DNA lesions may accumulate in sperm and be carried into the egg where, if not properly repaired, could result in the formation of heritable chromosomal aberrations or mutations and associated birth defects. Studies with female mice deficient in specific DNA repair genes have shown that: (i) cell cycle checkpoints are activated in the fertilized egg by DNA damage carried by the sperm; and (ii) the maternal genotype plays a major role in determining the efficiency of repairing genomic lesions in the fertilizing sperm and directly affect the risk for abnormal reproductive outcomes. There is also growing evidence that implicates DNA damage carried by the fertilizing gamete as a mediator of postfertilization processes that contribute to genomic instability in subsequent generations. Transgenerational genomic instability most likely involves epigenetic mechanisms or error-prone DNA repair processes in the early embryo. Maternal and embryonic DNA repair processes during the early phases of mammalian embryonic development can have far reaching consequences for the genomic integrity and health of subsequent generations.

  13. Multilayer sulfur-resistant composite metal membranes and methods of making and repairing the same

    DOE Patents [OSTI]

    Way, J. Douglas; Hatlevik, Oyvind

    2014-07-15

    The invention relates to thin, hydrogen-permeable, sulfur-resistant membranes formed from multi-layers of palladium or palladium-alloy coatings on porous, ceramic or metal supports, methods of making these membranes, methods of repairing layers of these membranes and devices that incorporate these membranes.

  14. Blue-Dam

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Irrigation Systems Upgrades Specifications and Requirements section added clarifying language, "Brass impact sprinklers shall be rebuilt by an established repair shop and shall...

  15. Solgel auto combustion synthesis of CoFe{sub 2}O{sub 4}/1-methyl-2-pyrrolidone nanocomposite with ethylene glycol: Its magnetic characterization

    SciTech Connect (OSTI)

    Topkaya, R.; Kurtan, U.; Junejo, Y.; Baykal, A.

    2013-09-01

    Graphical abstract: - Highlights: CoFe{sub 2}O{sub 4} was generated by solgel autocombustion using 1-methyl-2-pyrrolidone and ethylene glycol. The presence of spin-disordered surface layer on magnetic core was established. A linear dependence of the coercivity on temperature was fitted to Kneller's law. - Abstract: Magnetic nanoparticles were generated by solgel auto combustion synthesis of metal salts in the presence of 1-methyl-2-pyrrolidone, a functional solvent and ethylene glycol as usual solvent. The average crystallite size was obtained by using line profile fitting as 11 5 nm. The saturation magnetization value decreases with usage of the ethylene glycol in synthesis. The observed exchange bias effect further confirms the existence of the magnetically ordered core surrounded by spin-disordered surface layer and the ethylene glycol. Square-root temperature dependence of coercivity can be fitted to Kneller's law in the temperature range of 10400 K. The reduced remanent magnetization values lower than the theoretical value of 0.5 for non-interacting single domain particles indicate the CoFe{sub 2}O{sub 4}-1-methyl-2-pyrrolidone nanocomposite to have uniaxial anisotropy instead of the expected cubic anisotropy according to the StonerWohlfarth model.

  16. Acceptance for Beneficial Use for the 100K Service Water Pumps Auto Start Modifications Project 1K-97-3466M

    SciTech Connect (OSTI)

    MULLER, F.J.

    2000-03-27

    This Acceptance for Beneficial Use checklist covers the modifications to the K Basins service water pumps that added an auto-start function for reliability of the fire suppression system. The following information is to document the Acceptance for Beneficial Use (ABU) with a checklist and supporting information. The service water pumps have been modified so that on low system pressure after a time delay, the standby pump will automatically start. This ABU checklist matrix indicates the organizations that are responsible for the preparation of --or for the provision of input to--the identified documentation required by K Basins Operations. Looking at the items in the matrix, it can be seen that the subproject does not bear the sole responsibility for the generation of all these items. Rather, many items are outside of the subproject's scope such that other Spent Nuclear Fuel (SNF) organizations are needed to prepare or perform them (e.g., Training, Procedures, Facility Engineering, Startup, etc.). This supporting document, by virtue of all signatures approving it on the Engineering Data Transmittal, documents an agreement among the various represented disciplines and organizations within the SNF Project as to what is required in terms of documentation to transfer custody to Operations.

  17. Weld Repair of a Stamped Pressure Vessel in a Radiologically Controlled Zone

    SciTech Connect (OSTI)

    Cannell, Gary L.; Huth, Ralph J.; Hallum, Randall T.

    2013-08-26

    In September 2012 an ASME B&PVC Section VIII stamped pressure vessel located at the DOE Hanford Site Effluent Treatment Facility (ETF) developed a through-wall leak. The vessel, a steam/brine heat exchanger, operated in a radiologically controlled zone (by the CH2MHill PRC or CHPRC), had been in service for approximately 17 years. The heat exchanger is part of a single train evaporator process and its failure caused the entire system to be shut down, significantly impacting facility operations. This paper describes the activities associated with failure characterization, technical decision making/planning for repair by welding, logistical challenges associated with performing work in a radiologically controlled zone, performing the repair, and administrative considerations related to ASME code requirements.

  18. Subterranean barriers, methods, and apparatuses for forming, inspecting, selectively heating, and repairing same

    DOE Patents [OSTI]

    Nickelson, Reva A.; Sloan, Paul A.; Richardson, John G.; Walsh, Stephanie; Kostelnik, Kevin M.

    2009-04-07

    A subterranean barrier and method for forming same are disclosed, the barrier including a plurality of casing strings wherein at least one casing string of the plurality of casing strings may be affixed to at least another adjacent casing string of the plurality of casing strings through at least one weld, at least one adhesive joint, or both. A method and system for nondestructively inspecting a subterranean barrier is disclosed. For instance, a radiographic signal may be emitted from within a casing string toward an adjacent casing string and the radiographic signal may be detected from within the adjacent casing string. A method of repairing a barrier including removing at least a portion of a casing string and welding a repair element within the casing string is disclosed. A method of selectively heating at least one casing string forming at least a portion of a subterranean barrier is disclosed.

  19. Endovascular Repair of a Ruptured Mycotic Aneurysm of the Common Iliac Artery

    SciTech Connect (OSTI)

    Mofidi, R. Bhat, R.; Nagy, J.; Griffiths, G. D.; Chakraverty, S.

    2007-09-15

    This report describes the case of a ruptured mycotic aneurysm of the left common iliac artery, successfully treated with endovascular stent-grafting. A 64-year-old woman underwent diagnostic coronary angiography complicated by an infected hematoma of the left groin. Seven days later, she developed methicillin-resistant Staphylococcus aureus septicemia and CT scan evidence of perivascular inflammation around the left common iliac artery. This was followed by rupture of a mycotic aneurysm of the left common iliac artery. The lesion was successfully treated with a stent-graft and prolonged antibiotic therapy, and the patient remains free of infection 10 months later. Accumulating evidence suggests that endovascular repair can be used safely for the repair of ruptured infected aneurysms.

  20. Repair of localized defects in multilayer-coated reticle blanks for extreme ultraviolet lithography

    DOE Patents [OSTI]

    Stearns, Daniel G.; Sweeney, Donald W.; Mirkarimi, Paul B.

    2004-11-23

    A method is provided for repairing defects in a multilayer coating layered onto a reticle blank used in an extreme ultraviolet lithography (EUVL) system. Using high lateral spatial resolution, energy is deposited in the multilayer coating in the vicinity of the defect. This can be accomplished using a focused electron beam, focused ion beam or a focused electromagnetic radiation. The absorbed energy will cause a structural modification of the film, producing a localized change in the film thickness. The change in film thickness can be controlled with sub-nanometer accuracy by adjusting the energy dose. The lateral spatial resolution of the thickness modification is controlled by the localization of the energy deposition. The film thickness is adjusted locally to correct the perturbation of the reflected field. For example, when the structural modification is a localized film contraction, the repair of a defect consists of flattening a mound or spreading out the sides of a depression.

  1. Inhibition of Hsp27 Radiosensitizes Head-and-Neck Cancer by Modulating Deoxyribonucleic Acid Repair

    SciTech Connect (OSTI)

    Guttmann, David M.; Hart, Lori; Du, Kevin; Seletsky, Andrew; Koumenis, Constantinos

    2013-09-01

    Purpose: To present a novel method of tumor radiosensitization through Hsp27 knockdown using locked nucleic acid (LNA) and to investigate the role of Hsp27 in DNA double strand break (DSB) repair. Methods and Materials: Clonogenic survival assays, immunoblotting, the proximity ligation assay, and ?H2AX foci analysis were conducted in SQ20B and FaDu human head-and-neck cancer cell lines treated with Hsp27 LNA and Hsp27 short hairpin RNA (shRNA). Additionally, nude mice with FaDu flank tumors were treated with fractionated radiation therapy after pretreatment with Hsp27 LNA and monitored for tumor growth. Results: Hsp27 LNA and Hsp27 shRNA radiosensitized head-and-neck cancer cell lines in an Hsp27-dependent manner. Ataxia-Telangectasia Mutated-mediated DNA repair signaling was impaired in irradiated cells with Hsp27 knockdown. ATM kinase inhibition abrogated the radiosensitizing effect of Hsp27. Furthermore, Hsp27 LNA and shRNA both attenuated DNA repair kinetics after radiation, and Hsp27 was found to colocalize with ATM in both untreated and irradiated cells. Last, combined radiation and Hsp27 LNA treatment in tumor xenografts in nude mice suppressed tumor growth compared with either treatment alone. Conclusions: These results support a radiosensitizing property of Hsp27 LNA in vitro and in vivo, implicate Hsp27 in double strand break repair, and suggest that Hsp27 LNA might eventually serve as an effective clinical agent in the radiotherapy of head-and-neck cancer.

  2. Laser-activated nano-biomaterials for tissue repair and controlled drug release

    SciTech Connect (OSTI)

    Matteini, P; Ratto, F; Rossi, F; Pini, R

    2014-07-31

    We present recent achievements of minimally invasive welding of biological tissue and controlled drug release based on laser-activated nano-biomaterials. In particular, we consider new advancements in the biomedical application of near-IR absorbing gold nano-chromophores as an original solution for the photothermal repair of surgical incisions and as nanotriggers of controlled drug release from hybrid biopolymer scaffolds. (laser biophotonics)

  3. To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006

    Energy Savers [EERE]

    From: ecchimento@comcast.net [mailto:ecchimento@comcast.net] Sent: Monday, January 29, 2007 6:28 PM To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Larry, Regarding the planned line outage, scheduled for Feb. 20 through Mar. 6, I am requesting that the residents near the plant be moved for the duration of the outage to protect their health. Would you include this comment also in the ongoing recorded discussion? Thank you. Elizabeth -----Original Message-----

  4. Analysis and testing of the DIII-D ohmic heating coil lead repair clamp

    SciTech Connect (OSTI)

    Reis, E.E.; Anderson, P.M.; Chin, E.; Robinson, J.I.

    1997-11-01

    DIII-D has been operating for the last year with limited volt-second capabilities due to structural failure of a conductor lead to one of the ohmic heating (OH) solenoids. The conductor failure was due to poor epoxy impregnation of the overwrap of the lead pack, resulting in copper fatigue and a water leak. A number of structural analyses were performed to assist in determining the failure scenario and to evaluate various repair options. A fatigue stress analysis of the leads with a failed epoxy overwrap indicated crack initiation after 1,000 cycles at the maximum operating conditions. The failure occurred in a very inaccessible area which restricted design repair options to concepts which could be implemented remotely. Several design options were considered for repairing the lead so that it can sustain the loads for 7.5 Vs conditions at full toroidal field. A clamp, along with preloaded banding straps and shim bags, provides a system that guarantees that the stress at the crack location is always compressive and prevents further crack growth in the conductor. Due to the limited space available for the repair, it was necessary to design the clamp system to operate at the material yield stress. The primary components of the clamp system were verified by load tests prior to installation. The main body of the clamp contains a load cell and potentiometer for monitoring the load-deflection characteristics of the clamp and conductors during plasma operation. Strain gages provides redundant instrumentation. If required, the preload on the conductors can be increased remotely by a special wrench attached to the clamp assembly.

  5. Building America Top Innovations 2013 Profile … Window Replacement, Rehabilitation, & Repair Guide

    Energy Savers [EERE]

    Window Replacement, Rehabilitation, & Repair Guide TOP INNOVATOR: BSC Old single-glazed windows have such low thermal resistance that their effect on the overall thermal resistance of the walls can be staggering. Building America recommends several ways to improve the performance of existing windows at varying price points. Owners of older homes who want to improve their homes' efficiency often conclude that window replacement is a necessary first step. They are right that windows can be a

  6. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

    SciTech Connect (OSTI)

    Barnhoorn, Sander [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Uittenboogaard, Lieneke M. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Jaarsma, Dick [Erasmus Univ. Medical Center, Rotterdam (The Netherlands). Dept. of Neuroscience.; Vermeij, Wilbert P. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Tresini, Maria [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Weymaere, Michael [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Menoni, Herv [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Brandt, Renata M. C. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; de Waard, Monique C. [VU Univ. Medical Center, Amsterdam (The Netherlands). Dept. of Intensive Care.; Botter, Sander M. [Uniklinik Balgrist, Zurich (Switzerland); Sarker, Altaf H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Life Sciences Division.; Jaspers, Nicolaas G. J. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics; van der Horst, Gijsbertus T. J. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; Cooper, Priscilla K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Life Sciences Division.; Hoeijmakers, Jan H. J. [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics.; van der Pluijm, Ingrid [Erasmus University Medical Center, Rotterdam (The Netherlands). Dept. of Genetics and Dept. of Vascular Surgery.; Niedernhofer, Laura J. [The Scripps Research Institute, San Diego, CA (United States)

    2014-10-09

    As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relationship in XPG patients. Defects in XPG can cause either the cancer-prone condition xeroderma pigmentosum (XP) alone, or XP combined with the severe neurodevelopmental disorder Cockayne Syndrome (CS), or the infantile lethal cerebro-oculo-facio-skeletal (COFS) syndrome, characterized by dramatic growth failure, progressive neurodevelopmental abnormalities and greatly reduced life expectancy. Here, we present a novel (conditional) Xpg-/- mouse model whichin a C57BL6/FVB F1 hybrid genetic backgrounddisplays many progeroid features, including cessation of growth, loss of subcutaneous fat, kyphosis, osteoporosis, retinal photoreceptor loss, liver aging, extensive neurodegeneration, and a short lifespan of 45 months. We show that deletion of XPG specifically in the liver reproduces the progeroid features in the liver, yet abolishes the effect on growth or lifespan. In addition, specific XPG deletion in neurons and glia of the forebrain creates a progressive neurodegenerative phenotype that shows many characteristics of human XPG deficiency. Our findings therefore exclude that both the liver as well as the neurological phenotype are a secondary consequence of derailment in other cell types, organs or tissues (e.g. vascular abnormalities) and support a cell-autonomous origin caused by the DNA repair defect itself. In addition they allow the dissection of the complex aging process in tissue- and cell-type-specific components. Moreover, our data highlight the critical importance of genetic background in mouse aging studies, establish the Xpg-/- mouse as a valid model for the severe form of human XPG patients and segmental accelerated aging, and strengthen the link between DNA damage and aging.

  7. Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Barnhoorn, Sander; Uittenboogaard, Lieneke M.; Jaarsma, Dick; Vermeij, Wilbert P.; Tresini, Maria; Weymaere, Michael; Menoni, Hervé; Brandt, Renata M. C.; de Waard, Monique C.; Botter, Sander M.; et al

    2014-10-09

    As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relationship in XPG patients. Defects in XPG can cause either the cancer-prone condition xeroderma pigmentosum (XP) alone, or XP combined with the severe neurodevelopmental disorder Cockayne Syndrome (CS), or the infantile lethal cerebro-oculo-facio-skeletal (COFS) syndrome, characterized by dramatic growth failure, progressive neurodevelopmental abnormalities and greatly reduced life expectancy. Here, we present a novel (conditional) Xpg-/- mouse model which—in a C57BL6/FVB F1 hybrid genetic background—displays manymore » progeroid features, including cessation of growth, loss of subcutaneous fat, kyphosis, osteoporosis, retinal photoreceptor loss, liver aging, extensive neurodegeneration, and a short lifespan of 4–5 months. We show that deletion of XPG specifically in the liver reproduces the progeroid features in the liver, yet abolishes the effect on growth or lifespan. In addition, specific XPG deletion in neurons and glia of the forebrain creates a progressive neurodegenerative phenotype that shows many characteristics of human XPG deficiency. Our findings therefore exclude that both the liver as well as the neurological phenotype are a secondary consequence of derailment in other cell types, organs or tissues (e.g. vascular abnormalities) and support a cell-autonomous origin caused by the DNA repair defect itself. In addition they allow the dissection of the complex aging process in tissue- and cell-type-specific components. Moreover, our data highlight the critical importance of genetic background in mouse aging studies, establish the Xpg-/- mouse as a valid model for the severe form of human XPG patients and segmental accelerated aging, and strengthen the link between DNA damage and aging.« less

  8. Quality Improvement Guidelines for Imaging Detection and Treatment of Endoleaks following Endovascular Aneurysm Repair (EVAR)

    SciTech Connect (OSTI)

    Rand, T.; Uberoi, R.; Cil, B.; Munneke, G.; Tsetis, D.

    2013-02-15

    Major concerns after aortic aneurysm repair are caused by the presence of endoleaks, which are defined as persistent perigraft flow within the aortic aneurysm sac. Diagnosis of endoleaks can be performed with various imaging modalities, and indications for treatment are based on further subclassifications. Early detection and correct classification of endoleaks are crucial for planning patient management. The vast majority of endoleaks can be treated successfully by interventional means. Guidelines for Imaging Detection and Treatment of endoleaks are described in this article.

  9. ASTRID sodium cooled fast reactor: Program for improving in service inspection and repair

    SciTech Connect (OSTI)

    Jadot, F.; De Dinechin, G.; Augem, J. M.; Sibilo, J.

    2011-07-01

    In the frame of the CEA, EDF, AREVA coordinated research program for the development of Generation IV sodium-cooled fast reactors (SFR), the ASTRID project was launched in 2010. For the future prototype, the improvement of in-service inspection and repair (ISI and R) capabilities was identified as a major issue. Following the pluri-annual SFR research program, the ISI and R main R and D axes remain: i) improvement of the primary system conceptual design, ii) development of measurement and inspection techniques (continuous monitoring instrumentation and periodic inspection tools), iii) accessibility and associated robotics, and iv) development and validation of repair processes. Associated ISI and R needs are being defined through an iterative method between designers and instrumentation specialists: adaptation of the Design to ISI and R requirements, fission chamber development, validation of the ultrasonic and chemical transducers, of ultrasonic non destructive simulation, of acoustic surveillance, of laser repair intervention processes, of connected robotic equipment. Moreover, CEA, as leader of the ASTRID Project, is willing to find new contributors, partners or suppliers, in order to get innovative, diversified, exhaustive and efficient solutions. (authors)

  10. Relationship of DNA repair processes to mutagenesis and carcinogenesis in mammalian cells. Progress report, August 1, 1977-October 31, 1980

    SciTech Connect (OSTI)

    Evans, H.H.

    1980-10-01

    The objective of this research is to determine the role of DNA repair in mutagenesis and carcinogenesis in mammalian cells. More specifically, mutant strains will be selected which are deficient in various DNA repair pathways. These strains will be studied with regard to (1) the nature of the defect in repair, and (2) the mutability and transformability of the defective cells by various agents as compared to the wild type parental cells. The results to date include progress in the following areas: (1) determination of optimum conditions for growth and maintenance of cells and for quantitative measurement of various cellular parameters; (2) investigation of the effect of holding mutagenized cells for various periods in a density inhibited state on survival and on mutation and transformation frequencies; (3) examination of the repair capabilities of BHK cells, as compared to repair-proficient and repair-deficient human cells and excision-deficient mouse cells, as measured by the reactivation of Herpes simplex virus (HSV) treated with radiation and ethylmethane sulfonate (EMS); (4) initiation of host cell reactivation viral sucide enrichment and screening of survivors of the enrichment for sensitivity to ionizing radiation; and (5) investigation of the toxicity, mutagenicity, and carcinogenicity of various metabolites of 4-nitroquinoline-1-oxide (4-NQO). (ERB)

  11. Development and validation of nondestructive inspection techniques for composite doubler repairs on commercial aircraft

    SciTech Connect (OSTI)

    Roach, D.; Walkington, P.

    1998-05-01

    Composite doublers, or repair patches, provide an innovative repair technique which can enhance the way aircraft are maintained. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is possible to bond a single boron-epoxy composite doubler to the damaged structure. In order for the use of composite doublers to achieve widespread use in the civil aviation industry, it is imperative that methods be developed which can quickly and reliably assess the integrity of the doubler. In this study, a specific composite application was chosen on an L-1011 aircraft in order to focus the tasks on application and operation issues. Primary among inspection requirements for these doublers is the identification of disbonds, between the composite laminate and aluminum parent material, and delaminations in the composite laminate. Surveillance of cracks or corrosion in the parent aluminum material beneath the doubler is also a concern. No single nondestructive inspection (NDI) method can inspect for every flaw type, therefore it is important to be aware of available NDI techniques and to properly address their capabilities and limitations. A series of NDI tests were conducted on laboratory test structures and on full-scale aircraft fuselage sections. Specific challenges, unique to bonded composite doubler applications, were highlighted. An array of conventional and advanced NDI techniques were evaluated. Flaw detection sensitivity studies were conducted on applicable eddy current, ultrasonic, X-ray and thermography based devices. The application of these NDI techniques to composite doublers and the results from test specimens, which were loaded to provide a changing flaw profile, are presented in this report. It was found that a team of these techniques can identify flaws in composite doubler installations well before they reach critical size.

  12. Failures and repairs of headers and drums in fossil fired boilers

    SciTech Connect (OSTI)

    Thielsch, H.; Cone, F.

    1995-12-01

    This paper discusses failures which have occurred in a number of thick-walled pressure vessels including superheater and reheat outlet headers, and med and steam drums in fossil fired boilers. It provides details regarding the causes of failure, which range from original manufacturing defects to service-related deterioration such as creep and thermal fatigue. It also provides information regarding inspection techniques which are capable of detecting similar conditions before they have reached dangerous levels of deterioration. Finally, it provides details pertaining to techniques used to successfully repair these pressure vessels when they have failed.

  13. JAG Tearing Technique with Radiofrequency Guide Wire for Aortic Fenestration in Thoracic Endovascular Aneurysm Repair

    SciTech Connect (OSTI)

    Ricci, Carmelo; Ceccherini, Claudio Leonini, Sara; Cini, Marco; Vigni, Francesco; Neri, Eugenio; Tucci, Enrico; Benvenuti, Antonio; Tommasino, Giulio; Sassi, Carlo

    2012-02-15

    An innovative approach, the JAG tearing technique, was performed during thoracic endovascular aneurysm repair in a patient with previous surgical replacement of the ascending aorta with a residual uncomplicated type B aortic dissection who developed an aneurysm of the descending thoracic aorta with its lumen divided in two parts by an intimal flap. The proximal landing zone was suitable to place a thoracic stent graft. The distal landing zone was created by cutting the intimal flap in the distal third of the descending thoracic aorta with a radiofrequency guide wire and intravascular ultrasound catheter.

  14. BYD Auto | Open Energy Information

    Open Energy Info (EERE)

    to: navigation, search This article is a stub. You can help OpenEI by expanding it. A leader in batteries and EV. http:en.wikipedia.orgwikiBYDAuto Retrieved from "http:...

  15. Auto propane -- Some technical considerations

    SciTech Connect (OSTI)

    1998-12-31

    This booklet reviews some of the facts about propane as a vehicle fuel. It describes propane fuel properties, propane vehicle fuel systems and their components, propane vehicles and engines obtainable as original equipment from the vehicle manufacturer, after-market propane fuel system installations, propane vehicle operational characteristics, propane-fueled vehicle maintenance, government regulations and safety measures related to propane vehicles, and the environmental benefits of propane and propane-fueled vehicles. The final sections discuss the economics of propane vehicle ownership and the factors to be considered when estimating annual or lifetime savings or payback periods. Appendices include a directory of information sources, a sample worksheet for calculating payback, and examples of success stories relating the positive experiences of vehicle fleets with propane fueling.

  16. Connecting with the Auto Industry

    Broader source: Energy.gov [DOE]

    Under Secretary Steve Koonin reflects on his experience at the Center for Automotive Research's annual Management Briefing Seminar.

  17. auto | OpenEI Community

    Open Energy Info (EERE)

    Protection Agency Administrator, unveiled the joint effort, along with the Obama Administration, to create record fuel standards for vehicles built between 2017 and 2025...

  18. Dofasco`s No. 4 blast furnace hearth breakout, repair and rescue

    SciTech Connect (OSTI)

    Donaldson, R.J.; Fischer, A.J.; Sharp, R.M.; Stothart, D.W.

    1995-12-01

    On May 5, 1994, after producing 9.5 million metric tons of iron, Dofasco`s No. 4 Blast Furnace experienced a hearth breakout 250 millimeters below the west taphole. The hot metal spill caused a fire resulting in severe damage and 33 days of lost production. During a 26-day period, electrical wiring, water drainage systems and both tapholes were repaired. Recovery from an unprepared furnace stop of this length, with the deadman depleted is difficult. To aid with the rescue Hoogovens-designed oxygen/fuel lances were commissioned. The furnace recovery began with a lance in each taphole and all tuyeres plugged. Six days after startup the furnace was casting into torpedo cars, and after nine days operation had returned to normal. This incident prompted Dofasco to expand the hearth monitoring system to detect and prevent similar occurrences. During the repair, 203 new thermocouples were installed in the hearth, concentrating on the tapholes and elephant foot areas. These thermocouples were installed at various depths and locations to allow heat flux calculations. This hearth monitoring system has already identified other problem areas and provided valuable information about hearth drainage patterns. This information has allowed them to develop control strategies to manage localized problem areas.

  19. Operational results of shaft repair by installing stave type cooler at Kimitsu Nos. 3 and 4 blast furnaces

    SciTech Connect (OSTI)

    Oda, Hiroshi; Amano, Shigeru; Sakamoto, Aiichiro; Anzai, Osamu; Nakagome, Michiru; Kuze, Toshisuke; Imuta, Akira

    1997-12-31

    Nos. 3 and 4 blast furnaces in Nippon Steel Corporation Kimitsu Works were both initially fitted with cooling plate systems. With the aging of each furnace, the damage to their respective inner-shaft profiles had become serious. Thus, in order to prevent operational change and prolong the furnace life, the inner-shaft profile of each furnace was repaired by replacing the former cooling plate system with the stave type cooler during the two-week-shutdowns. With this repair, stability of burden descent and gas flow near the wall part of the furnace have been achieved. Thus the prolongation of the furnace life is naturally expected.

  20. Planning and care mark repair of 14-year old leak in Kuwait Oil Co. LPG tank 95

    SciTech Connect (OSTI)

    Shtayieh, S.

    1983-01-10

    This paper points out that the leak, which had been present for such a long time, completely saturated the perlite insulation with hydrocarbons, thus rendering the entire operation of inspection, repair, and maintenance of the inner tank a hazardous operation. It emphasizes the safety aspects, which were complicated by the saturated perlite as well as by the fact that the tank is situated in the middle of the LPG storage area with LPG tanks on either side. Tank design, making preparations, inspection, and repair are discussed. The fact that the leaking flanges were originally installed damaged, indicated the future need of tighter company quality control of all contractors work.

  1. Synthesis, characterization of double perovskite Ca{sub 2}MSbO{sub 6} (M = Dy, Fe, Cr, Al) materials via sol–gel auto-combustion and their catalytic properties

    SciTech Connect (OSTI)

    Feraru, S.; Samoila, P.; Borhan, A.I.; Ignat, M.; Iordan, A.R.; Palamaru, M.N.

    2013-10-15

    Double perovskite-type oxide Ca{sub 2}MSbO{sub 6} materials, where M = Dy, Fe, Cr, and Al, were prepared by using the sol–gel auto-combustion method. The role of different B-site cations on their synthesis, structures, morphologies and catalytic properties was investigated. The progress of double-perovskite type structure formation and the disappearance of the organic phases were monitored by infrared absorption spectroscopy (FTIR). Double perovskite oxide structures were evaluated using X-ray diffraction (XRD), while the microstructure of obtained compounds was studied using scanning electron microscopy (SEM). Also, BET surface areas were measured at the liquid nitrogen temperature by nitrogen adsorption. Catalytic properties of the obtained compounds were evaluated by test reaction of hydrogen peroxide decomposition. - Highlights: • Ca{sub 2}MSbO{sub 6} double perovskites were obtained by sol–gel auto-combustion method. • Ca{sub 2}MSbO{sub 6} (M = Dy, Fe, Cr and Al) as catalysts in H{sub 2}O{sub 2} decomposition • Strong relationship between particles' shape, BET area and catalytic performance • Ca{sub 2}FeSbO{sub 6} spherical grains show superior catalytic activity.

  2. Cadmium sulfate and CdTe-quantum dots alter DNA repair in zebrafish (Danio rerio) liver cells

    SciTech Connect (OSTI)

    Tang, Song; Cai, Qingsong; Chibli, Hicham; Allagadda, Vinay; Nadeau, Jay L.; Mayer, Gregory D.

    2013-10-15

    Increasing use of quantum dots (QDs) makes it necessary to evaluate their toxicological impacts on aquatic organisms, since their contamination of surface water is inevitable. This study compares the genotoxic effects of ionic Cd versus CdTe nanocrystals in zebrafish hepatocytes. After 24 h of CdSO{sub 4} or CdTe QD exposure, zebrafish liver (ZFL) cells showed a decreased number of viable cells, an accumulation of Cd, an increased formation of reactive oxygen species (ROS), and an induction of DNA strand breaks. Measured levels of stress defense and DNA repair genes were elevated in both cases. However, removal of bulky DNA adducts by nucleotide excision repair (NER) was inhibited with CdSO{sub 4} but not with CdTe QDs. The adverse effects caused by acute exposure of CdTe QDs might be mediated through differing mechanisms than those resulting from ionic cadmium toxicity, and studying the effects of metallic components may be not enough to explain QD toxicities in aquatic organisms. - Highlights: Both CdSO{sub 4} and CdTe QDs lead to cell death and Cd accumulation. Both CdSO{sub 4} and CdTe QDs induce cellular ROS generation and DNA strand breaks. Both CdSO{sub 4} and CdTe QDs induce the expressions of stress defense and DNA repair genes. NER repair capacity was inhibited with CdSO{sub 4} but not with CdTe QDs.

  3. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions

    SciTech Connect (OSTI)

    Zafar, Faria; Seidler, Sara B.; Kronenberg, Amy; Schild, David; Wiese, Claudia

    2010-06-29

    To test the contribution of homologous recombinational repair (HRR) in repairing DNA damaged sites induced by high-energy iron ions, we used: (1) HRR-deficient rodent cells carrying a deletion in the RAD51D gene and (2) syngeneic human cells impaired for HRR by RAD51D or RAD51 knockdown using RNA interference. We show that in response to iron ions, HRR contributes to cell survival in rodent cells, and that HRR-deficiency abrogates RAD51 foci formation. Complementation of the HRR defect by human RAD51D rescues both enhanced cytotoxicity and RAD51 foci formation. For human cells irradiated with iron ions, cell survival is decreased, and, in p53 mutant cells, the levels of mutagenesis are increased when HRR is impaired. Human cells synchronized in S phase exhibit more pronounced resistance to iron ions as compared with cells in G1 phase, and this increase in radioresistance is diminished by RAD51 knockdown. These results implicate a role for RAD51-mediated DNA repair (i.e. HRR) in removing a fraction of clustered lesions induced by charged particle irradiation. Our results are the first to directly show the requirement for an intact HRR pathway in human cells in ensuring DNA repair and cell survival in response to high-energy high LET radiation.

  4. Potential inspection, maintenance and repair techniques for the OTEC (Ocean Thermal Energy Conversion) systems

    SciTech Connect (OSTI)

    Not Available

    1983-02-01

    One of the major post-installation considerations of the OTEC platforms is the performance of underwater inspection, maintenance and repair (IMR) during their 30-year design life. In order to assist in the conceptual development of an IMR program, this study was undertaken using the two OTEC candidate configurations as a baseline. The objectives of the study were: (1) conduct an inventory of underwater Non-Destructive Examination (NDE) devices including a description of their performance capabilities, dimensional data, the areas of the various structures where they are most applicable, and a narrative description of the level of performance attained to date; (2) and to conduct an inventory of NDE device deployment vehicles which also includes a description of their performance capabilities, dimensional data, areas of the platform where they are most applicable as now designed and a relative comparison of these vehicles as to their ability to deploy the devices described in (1) above.

  5. Design structure for in-system redundant array repair in integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Quellette, Michael R.; Strissel, Scott A.

    2008-11-25

    A design structure for repairing an integrated circuit during operation of the integrated circuit. The integrated circuit comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The design structure provides the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The design structure further passes the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  6. Method and apparatus for in-system redundant array repair on integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc B.; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Ouellette, Michael R.; Strissel, Scott A.

    2008-07-29

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  7. Method and apparatus for in-system redundant array repair on integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc B.; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Ouellette, Michael R.; Strissel, Scott A.

    2008-07-08

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  8. Method and apparatus for in-system redundant array repair on integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc B.; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Ouellette, Michael R.; Strissel, Scott A.

    2007-12-18

    Disclosed is a method of repairing an integrated circuit of the type comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The method comprises the steps of providing the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The method comprises the further step of, at a given time, passing the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  9. Metal inhibition of human alkylpurine-DNA-N-glycosylase activityin base excision repair

    SciTech Connect (OSTI)

    Wang, Ping; Guliaev, Anton B.; Hang, Bo

    2006-02-28

    Cadmium (Cd{sup 2+}), nickel (Ni{sup 2+}) and cobalt (Co{sup 2+}) are human and/or animal carcinogens. Zinc (Zn{sup 2+}) is not categorized as a carcinogen, and rather an essential element to humans. Metals were recently shown to inhibit DNA repair proteins that use metals for their function and/or structure. Here we report that the divalent ions Cd{sup 2+}, Ni{sup 2+}, and Zn{sup 2+} can inhibit the activity of a recombinant human N-methylpurine-DNA glycosylase (MPG) toward a deoxyoligonucleotide with ethenoadenine (var epsilonA). MPG removes a variety of toxic/mutagenic alkylated bases and does not require metal for its catalytic activity or structural integrity. At concentrations starting from 50 to 1000 {micro}M, both Cd{sup 2+} and Zn{sup 2+} showed metal-dependent inhibition of the MPG catalytic activity. Ni{sup 2+} also inhibited MPG, but to a lesser extent. Such an effect can be reversed with EDTA addition. In contrast, Co{sup 2+} and Mg{sup 2+} did not inhibit the MPG activity in the same dose range. Experiments using HeLa cell-free extracts demonstrated similar patterns of inactivation of the var epsilonA excision activity by the same metals. Binding of MPG to the substrate was not significantly affected by Cd{sup 2+}, Zn{sup 2+}, and Ni{sup 2+} at concentrations that show strong inhibition of the catalytic function, suggesting that the reduced catalytic activity is not due to altered MPG binding affinity to the substrate. Molecular dynamics (MD) simulations with Zn{sup 2+} showed that the MPG active site has a potential binding site for Zn{sup 2+}, formed by several catalytically important and conserved residues. Metal binding to such a site is expected to interfere with the catalytic mechanism of this protein. These data suggest that inhibition of MPG activity may contribute to metal genotoxicity and depressed repair of alkylation damage by metals in vivo.

  10. Evaluating indoor exposure modeling alternatives for LCA: A case study in the vehicle repair industry

    SciTech Connect (OSTI)

    Demou, Evangelia; Hellweg, Stefanie; Wilson, Michael P.; Hammond, S. Katharine; McKone, Thomas E.

    2009-05-01

    We evaluated three exposure models with data obtained from measurements among workers who use"aerosol" solvent products in the vehicle repair industry and with field experiments using these products to simulate the same exposure conditions. The three exposure models were the: 1) homogeneously-mixed-one-box model, 2) multi-zone model, and 3) eddy-diffusion model. Temporally differentiated real-time breathing zone volatile organic compound (VOC) concentration measurements, integrated far-field area samples, and simulated experiments were used in estimating parameters, such as emission rates, diffusivity, and near-field dimensions. We assessed differences in model input requirements and their efficacy for predictive modeling. The One-box model was not able to resemble the temporal profile of exposure concentrations, but it performed well concerning time-weighted exposure over extended time periods. However, this model required an adjustment for spatial concentration gradients. Multi-zone models and diffusion-models may solve this problem. However, we found that the reliable use of both these models requires extensive field data to appropriately define pivotal parameters such as diffusivity or near-field dimensions. We conclude that it is difficult to apply these models for predicting VOC exposures in the workplace. However, for comparative exposure scenarios in life-cycle assessment they may be useful.

  11. Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling

    SciTech Connect (OSTI)

    Achar, Yathish Jagadheesh; Balogh, David; Neculai, Dante; Juhasz, Szilvia; Morocz, Monika; Gali, Himabindu; Dhe-Paganon, Sirano; Venclovas, Česlovas; Haracska, Lajos

    2015-09-08

    Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-binding, PCNA-polyubiquitin-ligase, and dsDNA-translocase activities, respectively. Here, we investigate the mechanism of HLTF action with emphasis on its HIRAN domain. We found that in cells HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain. Our biochemical assays show that HIRAN domain mutant HLTF proteins retain their ubiquitin ligase, ATPase and dsDNA translocase activities but are impaired in binding to a model replication fork. These data and our structural study indicate that the HIRAN domain recruits HLTF to a stalled replication fork, and it also provides the direction for the movement of the dsDNA translocase motor domain for fork reversal. We suggest functional similarities between the HIRAN, the OB, the HARP2, and other domains found in certain motor proteins, which may explain why only a subset of DNA translocases can carry out fork reversal.

  12. Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Achar, Yathish Jagadheesh; Balogh, David; Neculai, Dante; Juhasz, Szilvia; Morocz, Monika; Gali, Himabindu; Dhe-Paganon, Sirano; Venclovas, Česlovas; Haracska, Lajos

    2015-09-08

    Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-binding, PCNA-polyubiquitin-ligase, and dsDNA-translocase activities, respectively. Here, we investigate the mechanism of HLTF action with emphasis on its HIRAN domain. We found that in cells HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain. Our biochemical assays show that HIRAN domain mutant HLTF proteinsmore » retain their ubiquitin ligase, ATPase and dsDNA translocase activities but are impaired in binding to a model replication fork. These data and our structural study indicate that the HIRAN domain recruits HLTF to a stalled replication fork, and it also provides the direction for the movement of the dsDNA translocase motor domain for fork reversal. We suggest functional similarities between the HIRAN, the OB, the HARP2, and other domains found in certain motor proteins, which may explain why only a subset of DNA translocases can carry out fork reversal.« less

  13. Homologous recombination and non-homologous end-joining repair pathways in bovine embryos with different developmental competence

    SciTech Connect (OSTI)

    Henrique Barreta, Marcos; Laboratorio de Biotecnologia e Reproducao Animal-BioRep, Universidade Federal de Santa Maria, Santa Maria, RS ; Garziera Gasperin, Bernardo; Braga Rissi, Vitor; Cesaro, Matheus Pedrotti de; Ferreira, Rogerio; Oliveira, Joao Francisco de; Goncalves, Paulo Bayard Dias; Bordignon, Vilceu

    2012-10-01

    This study investigated the expression of genes controlling homologous recombination (HR), and non-homologous end-joining (NHEJ) DNA-repair pathways in bovine embryos of different developmental potential. It also evaluated whether bovine embryos can respond to DNA double-strand breaks (DSBs) induced with ultraviolet irradiation by regulating expression of genes involved in HR and NHEJ repair pathways. Embryos with high, intermediate or low developmental competence were selected based on the cleavage time after in vitro insemination and were removed from in vitro culture before (36 h), during (72 h) and after (96 h) the expected period of embryonic genome activation. All studied genes were expressed before, during and after the genome activation period regardless the developmental competence of the embryos. Higher mRNA expression of 53BP1 and RAD52 was found before genome activation in embryos with low developmental competence. Expression of 53BP1, RAD51 and KU70 was downregulated at 72 h and upregulated at 168 h post-insemination in response to DSBs induced by ultraviolet irradiation. In conclusion, important genes controlling HR and NHEJ DNA-repair pathways are expressed in bovine embryos, however genes participating in these pathways are only regulated after the period of embryo genome activation in response to ultraviolet-induced DSBs.

  14. Radiation-Induced Upregulation of Gene Expression From Adenoviral Vectors Mediated by DNA Damage Repair and Regulation

    SciTech Connect (OSTI)

    Nokisalmi, Petri; Rajecki, Maria; Pesonen, Sari; Escutenaire, Sophie; Soliymani, Rabah; Tenhunen, Mikko; Ahtiainen, Laura; Hemminki, Akseli

    2012-05-01

    Purpose: In the present study, we evaluated the combination of replication-deficient adenoviruses and radiotherapy in vitro. The purpose of the present study was to analyze the mechanism of radiation-mediated upregulation of adenoviral transgene expression. Methods and Materials: Adenoviral transgene expression (luciferase or green fluorescent protein) was studied with and without radiation in three cell lines: breast cancer M4A4-LM3, prostate cancer PC-3MM2, and lung cancer LNM35/enhanced green fluorescent protein. The effect of the radiation dose, modification of the viral capsid, and five different transgene promoters were studied. The cellular responses were studied using mass spectrometry and immunofluorescence analysis. Double strand break repair was modulated by inhibitors of heat shock protein 90, topoisomerase-I, and DNA protein kinase, and transgene expression was measured. Results: We found that a wide range of radiation doses increased adenoviral transgene expression regardless of the cell line, transgene, promoter, or viral capsid modification. Treatment with adenovirus, radiation, and double strand break repair inhibitors resulted in persistence of double strand breaks and subsequent increases in adenovirus transgene expression. Conclusions: Radiation-induced enhancement of adenoviral transgene expression is linked to DNA damage recognition and repair. Radiation induces a global cellular response that results in increased production of RNA and proteins, including adenoviral transgene products. This study provides a mechanistic rationale for combining radiation with adenoviral gene delivery.

  15. Repair of radiation-induced heat-labile sites is independent of DNA-PKcs, XRCC1 or PARP

    SciTech Connect (OSTI)

    Stenerlw, Bo; Karlsson, Karin H.; Radulescu, Irina; Rydberg, Bjorn; Stenerlow, Bo

    2008-04-29

    Ionizing radiation induces a variety of different DNA lesions: in addition to the most critical DNA damage, the DSB, numerous base alterations, SSBs and other modifications of the DNA double-helix are formed. When several non-DSB lesions are clustered within a short distance along DNA, or close to a DSB, they may interfere with the repair of DSBs and affect the measurement of DSB induction and repair. We have previously shown that a substantial fraction of DSBs measured by pulsed-field gel electrophoresis (PFGE) are in fact due to heat-labile sites (HLS) within clustered lesions, thus reflecting an artifact of preparation of genomic DNA at elevated temperature. To further characterize the influence of HLS on DSB induction and repair, four human cell lines (GM5758, GM7166, M059K, U-1810) with apparently normal DSB rejoining were tested for bi-phasic rejoining after gamma irradiation. When heat-released DSBs were excluded from the measurements the fraction of fast rejoining decreased to less than 50% of the total. However, neither the half-times of the fast (t{sub 1/2} = 7-8 min) or slow (t{sub 1/2} = 2.5 h) DSB rejoining were changed significantly. At t=0 the heat-released DSBs accounted for almost 40% of the DSBs, corresponding to 10 extra DSB/cell/Gy in the initial DSB yield. These heat-released DSBs were repaired within 60-90 min in all tested cells, including M059K cells treated with wortmannin or DNA-PKcs defect M059J cells. Furthermore, cells lacking XRCC1 or Poly(ADP-ribose) polymerase-1 (PARP-1) rejoined both total DSBs and heat-released DSBs similar to normal cells. In summary, the presence of heat-labile sites have a substantial impact on DSB induction yields and DSB rejoining rates measured by pulsed-field gel electrophoresis, and HLS repair is independent of DNA-PKcs, XRCC1 and PARP.

  16. JEA- ShopSmart Residential Rebate Program

    Broader source: Energy.gov [DOE]

    In order to receive rebates for window tinting, heat pumps, or central air conditioners, interested customers should contact a pre-qualified contractor to perform an assessment. The rebate from...

  17. Shopping for Appliances | Department of Energy

    Office of Environmental Management (EM)

    Department of Energy Seneca Nation of Indians Leverages DOE Support for Wind Turbine Project Seneca Nation of Indians Leverages DOE Support for Wind Turbine Project April 28, 2016 - 11:19am Addthis Office of Indian Energy Chris Deschene (third from the right) was among those in attendance at a groundbreaking ceremony the Seneca Nation of Indians held for its 1.5-MW wind turbine on April 27. Photo by Ken Parker, Food Is Our Medicine. Office of Indian Energy Chris Deschene (third from the

  18. Technical Shop Machinist | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and lathes to fabricate complex parts from stainless steel, copper, aluminum, titanium, inconnel, etc from information on blueprints, dxf files, sketches and from verbal...

  19. Heavy Mobile Equipment Mechanic (1 Mechanic Shop)

    Broader source: Energy.gov [DOE]

    A successful candidate will perform preventative, predictive, and corrective maintenance on Bonneville Power Administration (BPA's) light and heavy mobile equipment in maintenance and filed...

  20. Tips: Shopping for Appliances | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Appliances July 16, 2014 - 7:33pm Addthis What's the real cost? Every appliance has two price tags -- the purchase price and the operating cost. Consider both when buying a new...

  1. Tips: Shopping for Lighting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    to the EnergyGuide label) Lifespan Light appearance (from warm to cool) Light appearance, measured by correlated color temperature (CCT) on the Kelvin (K) scale, from warm to cool. ...

  2. Weatherization Assistance Available at Florida Pie Shop

    Broader source: Energy.gov [DOE]

    Pie in the Sky, a seemingly simple store that offers customers fresh-baked desserts, is providing a second treat: weatherization.

  3. Suspended Solids Profiler Shop Test Report

    SciTech Connect (OSTI)

    STAEHR, T.W.

    2000-01-19

    The Suspended Solids Profiler (SSP) Instrument is planned to be installed in the AZ-101 tank to measure suspended solids concentrations during mixer pump testing. The SSP sensor uses a reflectance measurement principle to determine the suspended solids concentrations. The purpose of this test is to provide a documented means of verifying that the functional components of the SSP operate properly.

  4. Building Green in Greensburg: Dillons Kwik Shop

    Office of Energy Efficiency and Renewable Energy (EERE)

    This poster highlights energy efficiency, renewable energy, and sustainable features of the high-performing Dillons Kwik Stop building in Greensburg, Kansas.

  5. Heavy Mobile Equipment Mechanic (One Mechanic Shop)

    Broader source: Energy.gov [DOE]

    Join the Bonneville Power Administration (BPA) for a challenging and rewarding career, while working, living, and playing in the Pacific Northwest. The Heavy Mobile Equipment Mechanic (One Mechanic...

  6. 2715-WA_Carpenter's_Shop_Refurbishment.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  7. Tips: Shopping for Lighting | Department of Energy

    Energy Savers [EERE]

    Lifespan Light appearance (from warm to cool) Light appearance, measured by correlated color temperature (CCT) on the Kelvin (K) scale, from warm to cool. Like the helpful...

  8. Identification of Intrinsic Order and Disorder in the DNA Repair Protein XPA

    SciTech Connect (OSTI)

    Iakoucheva, Lilia M.; Kimzey, Amy L.; Masselon, Christophe D.; Bruce, James E.; Garner, Ethan C.; Brown, Celeste J.; Dunker, A. K.; Smith, Richard D.; Ackerman, Eric J.

    2001-03-01

    The damage recognition protein XPA is required to recognize a wide variety of bulky lesions during nucleotide excision repair (NER). Independent NMR solution structures of a human XPA protein (hXPA) fragment comprising approximately one-third of the full-length protein, the minimal DNA-binding domain (MBD), revealed that ~30% of the molecule was structurally disordered. To better characterize structural features of XPA, we performed time-resolved trypsin proteolysis on active, full-length recombinant Xenopus XPA protein (xXPA). The resulting proteolytic fragments were analyzed by electrospray ionization interface coupled to a Fourier transform ion cyclotron resonance (ESI-FTICR) mass spectrometry, SDS-polyacrylamide gel electrophoresis (PAGE), and selected N-terminal sequence determinations. The mass spectrum of the full-length xXPA was consistent with the predicted sequence, 30922.02 vs. 30922.45 Da; respectively. Moreover, the mass spectrometric data allowed the assignment of multiple xXPA fragments not resolvable by SDS PAGE. Full-length xXPA exhibited aberrant mobility on SDS-PAGE with an apparent MW of ~40 kDa. To test predictions that a Glu-rich region (E70-E76) or other local regions of high charge were responsible for this ~40% aberrant SDS-PAGE mobility, the MW's of partial proteolytic fragments from ~5 to 25 kDa precisely determined by ESI-FTICR MS were correlated with their gel positions. Surprisingly, all tested partial tryptic fragments within this size-range exhibited 10-42% divergence between calculated MW and that estimated by SDS-PAGE, thus indicating the origin of anomalous migration of XPA is not localized. The computer program Predictor of Natural Disordered Regions (PONDR) correctly identified several regions of xXPA either sensitive or resistant to partial proteolysis, thereby indicating that disorder in XPA shares sequence features with other well-characterized intrinsically unstructured proteins.

  9. Large Diameter Limbs for Dilated Common Iliac Arteries in Endovascular Aneurysm Repair. Is It Safe?

    SciTech Connect (OSTI)

    Malagari, Katerina Brountzos, Elias; Gougoulakis, Alexandros; Papathanasiou, Matilda; Alexopoulou, Efthymia; Mastorakou, Renata; Kelekis, Dimitris

    2004-09-15

    In this prospective study we examined whether dilated common iliac arteries (CIAs) can provide a safe distal seal in endovascular aneurysm repair (EVAR) with the use of bifurcated stent grafts with large diameter limbs. Sixteen patients with 26 dilated CIAs with a diameter of {>=}6 mm who were offered EVAR using stent grafts with large diameter limbs were included in the study (Group A). Forty-two patients who also underwent EVAR without iliac dilatation, matched for age, sex and surgical risk were used for comparison (controls-Group B). In group A mean CIA diameter was 18.2 mm (16-28) and mean abdominal aortic aneurysm (AAA) diameter was 6.87 {+-} 1.05 cm; mean age was 77.2 {+-} 4.8 yrs (67-81). Mean follow-up was 33.6 months (2.8 yrs). CIA diameter changes and development of endoleaks were assessed by CT angiography (CTA). Overall iliac dilatation was present in 16/58 of our patients (27.6%). In 10 patients dilatation was bilateral (17.3%). Partial or complete flow to the internal iliac artery (IIA) territories was preserved in all patients post-EVAR. On follow-up, stable caliber of the dilated CIAs was observed in 21 patients (84%), enlargement of 1mm in 3 (16%), and failure of the distal attachment in 1 (6.2%). Compared to the control group there was no statistical significance in the incidence of complications. Dilated common iliac arteries provide a safe distal seal in patients who have undergone EVAR, thus obviating the need for additional endovascular procedures and sparing flow in the IIA vascular bed.

  10. Chemical repair of base lesions, AP-sites, and strand breaks on plasmid DNA in dilute aqueous solution by ascorbic acid

    SciTech Connect (OSTI)

    Hata, Kuniki; Advanced Science Research Center, Japan Atomic Energy Agency, 2-4 Shirakatashirane, Tokai-mura, Naka-gun, Ibaraki 319-1195 ; Urushibara, Ayumi; Yamashita, Shinichi; Shikazono, Naoya; Yokoya, Akinari; Katsumura, Yosuke; Nuclear Professional School, School of Engineering, The University of Tokyo, 2-22 Shirakatashirane, Tokai-mura, Naka-gun, Ibaraki 319-1188

    2013-05-03

    Highlights: We report a novel mechanism of radiation protection of DNA by chemical activity of ascorbic acid. The chemical repair of DNA damage was revealed using biochemical assay and chemical kinetics analysis. We found that ascorbic acid significantly repairs precursors of nucleobase lesions and abasic sites. However, ascorbic acid seldom repairs precursors of DNA-strand breaks. -- Abstract: We quantified the damage yields produced in plasmid DNA by ?-irradiation in the presence of low concentrations (10100 ?M) of ascorbic acid, which is a major antioxidant in living systems, to clarify whether it chemically repairs radiation damage in DNA. The yield of DNA single strand breaks induced by irradiation was analyzed with agarose gel electrophoresis as conformational changes in closed circular plasmids. Base lesions and abasic sites were also observed as additional conformational changes by treating irradiated samples with glycosylase proteins. By comparing the suppression efficiencies to the induction of each DNA lesion, in addition to scavenging of the OH radicals derived from water radiolysis, it was found that ascorbic acid promotes the chemical repair of precursors of AP-sites and base lesions more effectively than those of single strand breaks. We estimated the efficiency of the chemical repair of each lesion using a kinetic model. Approximately 5060% of base lesions and AP-sites were repaired by 10 ?M ascorbic acid, although strand breaks were largely unrepaired by ascorbic acid at low concentrations. The methods in this study will provide a route to understanding the mechanistic aspects of antioxidant activity in living systems.

  11. New Technologies for Repairing Aging Cables in Nuclear Power Plants: M3LW-14OR0404015 Cable Rejuvenation Report

    SciTech Connect (OSTI)

    Simmons, Kevin L.; Fifield, Leonard S.; Westman, Matthew P.; Roberts, John A.

    2014-09-08

    The goal of this project is to conceptually demonstrate techniques to repair cables that have degraded through subjection to long-term thermal and radiation exposure in nuclear power plants. In fiscal year 2014 (FY14) we focused on commercially available ethylene-propylene rubber (EPR) as the relevant test material, isolated a high surface area form of the EPR material to facilitate chemical treatment screening and charaterization, and measured chemical changes in the material due to aging and treatment using Fourier Transfrom Infrared (FTIR) spectroscopy.

  12. Evaluating the integrity of the reinforced concrete structure repaired by epoxy injection using simulated transfer function of impact-echo response

    SciTech Connect (OSTI)

    Cheng, Chia-Chi; Yu, Chih-peng; Wu, Jiunn-Hong; Hsu, Keng-Tsan; Ke, Ying-Tsu

    2014-02-18

    Cracks and honeycombs are often found inside reinforced concrete (RC) structure caused by excessive external force, or improper casting of concrete. The repairing method usually involves epoxy injection. The impact-echo method, which is a sensitive for detecting of the interior voids, may not be applicable to assess the integrity of the repaired member as both air and epoxy are less in acoustic impedances. In this study, the repaired RC structure was evaluated by the simulated transfer function of the IE displacement waveform where the R-wave displacement waveform is used as a base of a simulated force-time function. The effect of different thickness of the epoxy layer to the amplitude corresponding to the interface is studied by testing on specimen containing repaired naturally delaminated cracks with crack widths about 1 mm, 3 mm and 5 mm. The impact-echo responses were compared with the drilling cores at the test positions. The results showed the cracks were not fully filled with epoxy when the peak amplitude corresponding to the interface dropped less than 20%. The peak corresponding to the thicker epoxy layer tends to be larger in amplitude. A field study was also performed on a column damaged by earthquake before and after repairing.

  13. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Ruben A. Abagyan, PhD

    2004-04-15

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  14. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Abagyan, Ruben; An, Jianghong

    2005-08-12

    DNA Damage Recognition and Repair (DDR&R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. We have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR&R process. The significant achievements of this project include: 1) Construction of the computational pipeline for searching DDR&R genes, building and validation of 3D models of proteins involved in DDR&R; 2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; and the development of a method to predict the effects of mutations. Large scale testing of technology to identify novel small binding pockets in protein structures leading to new DDRR inhibitor strategies 3) Improvements of macromolecular docking technology (see the CAPRI 1-3 and 4-5 results) 4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; 5) Construction and maintenance of the DNA Damage Recognition and Repair Database; 6) Producing 15 research papers (12 published and 3 in preparation).

  15. Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis

    SciTech Connect (OSTI)

    Dong, Hui; Shi, Qiong; Song, Xiufang; Fu, Juanli; Hu, Lihua; Xu, Demei; Su, Chuanyang; Xia, Xiaomin; Song, Erqun; Song, Yang

    2015-07-01

    Our previous studies demonstrated that polychlorinated biphenyl (PCB) quinone induced oxidative DNA damage in HepG2 cells. To promote genomic integrity, DNA damage response (DDR) coordinates cell-cycle transitions, DNA repair and apoptosis. PCB quinone-induced cell cycle arrest and apoptosis have been documented, however, whether PCB quinone insult induce DNA repair signaling is still unknown. In this study, we identified the activation of DDR and corresponding signaling events in HepG2 cells upon the exposure to a synthetic PCB quinone, PCB29-pQ. Our data illustrated that PCB29-pQ induces the phosphorylation of p53, which was mediated by ataxia telangiectasia mutated (ATM) protein kinase. The observed phosphorylated histone H2AX (γ-H2AX) foci and the elevation of 8-hydroxy-2′-deoxyguanosine (8-OHdG) indicated that DDR was stimulated by PCB29-pQ treatment. Additionally, we found PCB29-pQ activates non-homologous end joining (NHEJ), base excision repair (BER) and nucleotide excision repair (NER) signalings. However, these repair pathways are not error-free processes and aberrant repair of DNA damage may cause the potential risk of carcinogenesis and mutagenesis. - Highlights: • Polychlorinated biphenyl quinone induces oxidative DNA damage in HepG2 cells. • The elevation of γ-H2AX and 8-OHdG indicates the activation of DNA damage response. • ATM-p53 signaling acts as the DNA damage sensor and effector. • Polychlorinated biphenyl quinone activates NHEJ, BER and NER signalings.

  16. Missouri School District Charges Up

    Broader source: Energy.gov [DOE]

    Missouri's Lee's Summit R-7 school district's distribution fleet was tired. Many of the vehicles had racked up more than 300,000 miles and made frequent trips to the shop to repair the 20 plus-year-old parts.

  17. Evaluation and Repair of Primary Water Stress Corrosion Cracking in Alloy 600/182 Control Rod Drive Mechanism Nozzles

    SciTech Connect (OSTI)

    Frye, Charles R.; Arey, Melvin L. Jr.; Robinson, Michael R.; Whitaker, David E.

    2002-07-01

    In February 2001, a routine visual inspection of the reactor vessel head of Oconee Nuclear Station Unit 3 identified boric acid crystals at nine of sixty-nine locations where control rod drive mechanism housings (CRDM nozzles) penetrate the head. The boric acid deposits resulted from primary coolant leaking from cracks in the nozzle attachment weld and from through-thickness cracks in the nozzle wall. A general overview of the inspection and repair process is presented and results of the metallurgical analysis are discussed in more detail. The analysis confirmed that primary water stress corrosion cracking (PWSCC) is the mechanism of failure of both the Alloy 182 weld filler material and the alloy 600 wrought base material. (authors)

  18. Southeast Propane AutoGas Development Program

    Broader source: Energy.gov [DOE]

    2011 DOE Hydrogen and Fuel Cells Program, and Vehicle Technologies Program Annual Merit Review and Peer Evaluation

  19. Southeast Propane AutoGas Development Program

    Broader source: Energy.gov [DOE]

    2010 DOE Vehicle Technologies and Hydrogen Programs Annual Merit Review and Peer Evaluation Meeting, June 7-11, 2010 -- Washington D.C.

  20. Auto-Versioning Systems Image Manager

    Energy Science and Technology Software Center (OSTI)

    2013-08-01

    The av_sys_image_mgr utility provides an interface for the creation, manipulation, and analysis of system boot images for computer systems. It is primarily intended to provide a convenient method for managing the introduction of changes to boot images for long-lived production HPC systems.

  1. Less platinum means lower prices for autos

    Office of Energy Efficiency and Renewable Energy (EERE)

    How technology developed by researchers at 3M is reducing the amount of platinum necessary for a fuel cell system, helping to make the technology more practical for consumer vehicles.

  2. Auto-steering apparatus and method

    DOE Patents [OSTI]

    McKay, Mark D.; Anderson, Matthew O.

    2007-03-13

    A vehicular guidance method involves providing a user interface using which data can be input to establish a contour for a vehicle to follow, the user interface further configured to receive information from a differential global positioning system (DGPS), determining cross track and offset data using information received from the DGPS, generating control values, using at least vehicular kinematics, the cross track, and the offset data, and providing an output to control steering of the vehicle, using the control values, in a direction to follow the established contour while attempting to minimize the cross track and the offset data.

  3. Southeast Propane AutoGas Development Program

    Broader source: Energy.gov [DOE]

    2012 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting

  4. Promising Technology: Auto Sash Fume Hoods

    Broader source: Energy.gov [DOE]

    Automatic sash closure systems use an occupancy sensor control system to close the sash when no occupants are detected.

  5. Photo Gallery: 2016 Washington Auto Show

    Broader source: Energy.gov [DOE]

    Scroll through the photos to see some of the Energy Department-supported technologies that are lowering carbon pollution and moving America’s economy forward.

  6. Financing the Growing American Auto Industry

    Broader source: Energy.gov [DOE]

    The Department announced a conditional commitment for a $259 million Advanced Technology Vehicles Manufacturing (ATVM) loan to aluminum manufacturer Alcoa, Inc. that would support the company’s Alcoa, Tennessee, manufacturing facility, where the company will produce high-strength aluminum sheet for North American automakers looking to lightweight their vehicles.

  7. Benchmarking for electric utilities, tree trimming benchmarking, service line installation to single family residence, and distribution revenue meter testing and repair

    SciTech Connect (OSTI)

    Harder, J.

    1994-12-31

    An American Public Power Association (APPA) task force study on benchmarking for electric utilities is presented. Benchmark studies were made of three activities: (1) Tree trimming; (2) Service line installation to single family residence; (3) Distribution revenue meter testing and repair criteria. The results of the study areas are summarized for 15 utilities. The methodologies used for data collection and analysis are discussed. 28 figs., 9 tabs.

  8. Study to develop an inspection, maintenance, and repair plan for OTEC (Ocean Thermal Energy Conversion) modular experiment plants. Final report

    SciTech Connect (OSTI)

    Not Available

    1980-04-01

    The inspection, maintenance and repair (IM and R) of the Ocean Thermal Energy Conversion (OTEC) Modular Experiment Plant (Pilot Plant) have been studied in two phases: Task I and Task II. Task I phase developed IM and R identification forms, identified requirements for routine and post casualty IM and R, and categorized and outlined potential procedures to perform IM and R activities. The efforts of the Task II phase have been directed to meet the following objectives: to provide feedback to the OTEC marine systems designs to assure that such designs reflect appropriate consideration of IM and R methods and unit costs, resulting in designs with reduced life cycle costs; to include technical information concerning OTEC IM and R possibilities to NOAA/DOE; to outline a basis in which the anticipated IM and R contributions to life cycle costs can be developed for any specific OTEC plant design; to identify IM and R methods within the state-of-the-art in the offshore industry; to determine the application of potential IM and R procedures for the commercial operation of OTEC 10/40 Pilot Plant(s); and input into the US government formulation of statutory and regulatory IM and R requirements for OTEC plants.

  9. Construction of nerve guide conduits from cellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect

    SciTech Connect (OSTI)

    Luo, Lihua; Gan, Li; Liu, Yongming; Tian, Weiqun; Tong, Zan; Wang, Xiong; Huselstein, Celine; Chen, Yun

    2015-02-20

    Regeneration and functional reconstruction of peripheral nerve defects remained a significant clinical challenge. Nerve guide conduits, with seed cells or neurotrophic factors (NTFs), had been widely used to improve the repair and regeneration of injured peripheral nerve. Pyrroloquinoline quinone (PQQ) was an antioxidant that can stimulate nerve growth factors (NGFs) synthesis and accelerate the Schwann cells (SCs) proliferation and growth. In present study, three kinds of nerve guide conduits were constructed: one from cellulose/SPI hollow tube (CSC), another from CSC combined with SCs (CSSC), and the third one from CSSC combined with PQQ (CSSPC), respectively. And then they were applied to bridge and repair the sciatic nerve defect in rats, using autograft as control. Effects of different nerve guide conduits on the nerve regeneration were comparatively evaluated by general analysis, sciatic function index (SFI) and histological analysis (HE and TEM). Newly-formed regenerative nerve fibers were observed and running through the transparent nerve guide conduits 12 weeks after surgery. SFI results indicated that the reconstruction of motor function in CSSPC group was better than that in CSSC and CSC groups. HE images from the cross-sections and longitudinal-sections of the harvested regenerative nerve indicated that regenerative nerve fibers had been formed and accompanied with new blood vessels and matrix materials in the conduits. TEM images also showed that lots of fresh myelinated and non-myelinated nerve fibers had been formed. Parts of vacuolar, swollen and abnormal axons occurred in CSC and CSSC groups, while the vacuolization and swell of axons was the least serious in CSSPC group. These results indicated that CSSPC group had the most ability to repair and reconstruct the nerve structure and functions due to the comprehensive contributions from hollow CSC tube, SCs and PQQ. As a result, the CSSPC may have the potential for the applications as nerve guide conduits in the field of nerve tissue engineering. - Highlights: • A novel nerve conduit was constructed and applied to repair nerve defect in rats. • Transparent hollow cellulose/soy protein isolate tube was used as conduit matrix. • Pyrroloquinoline quinine was adsorbed into the hollow tube as nerve growth factor. • Schwann cells were cultured into the hollow tube as seed cells. • The new nerve conduit could repair and reconstruct the peripheral nerve defects.

  10. Maximum Diameter Measurements of Aortic Aneurysms on Axial CT Images After Endovascular Aneurysm Repair: Sufficient for Follow-up?

    SciTech Connect (OSTI)

    Baumueller, Stephan Nguyen, Thi Dan Linh Goetti, Robert Paul; Lachat, Mario; Seifert, Burkhardt; Pfammatter, Thomas Frauenfelder, Thomas

    2011-12-15

    Purpose: To assess the accuracy of maximum diameter measurements of aortic aneurysms after endovascular aneurysm repair (EVAR) on axial computed tomographic (CT) images in comparison to maximum diameter measurements perpendicular to the intravascular centerline for follow-up by using three-dimensional (3D) volume measurements as the reference standard. Materials and Methods: Forty-nine consecutive patients (73 {+-} 7.5 years, range 51-88 years), who underwent EVAR of an infrarenal aortic aneurysm were retrospectively included. Two blinded readers twice independently measured the maximum aneurysm diameter on axial CT images performed at discharge, and at 1 and 2 years after intervention. The maximum diameter perpendicular to the centerline was automatically measured. Volumes of the aortic aneurysms were calculated by dedicated semiautomated 3D segmentation software (3surgery, 3mensio, the Netherlands). Changes in diameter of 0.5 cm and in volume of 10% were considered clinically significant. Intra- and interobserver agreements were calculated by intraclass correlations (ICC) in a random effects analysis of variance. The two unidimensional measurement methods were correlated to the reference standard. Results: Intra- and interobserver agreements for maximum aneurysm diameter measurements were excellent (ICC = 0.98 and ICC = 0.96, respectively). There was an excellent correlation between maximum aneurysm diameters measured on axial CT images and 3D volume measurements (r = 0.93, P < 0.001) as well as between maximum diameter measurements perpendicular to the centerline and 3D volume measurements (r = 0.93, P < 0.001). Conclusion: Measurements of maximum aneurysm diameters on axial CT images are an accurate, reliable, and robust method for follow-up after EVAR and can be used in daily routine.

  11. The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

    SciTech Connect (OSTI)

    Trego, Kelly S.; Chernikova, Sophia B.; Davalos, Albert R.; Perry, J. Jefferson P.; Finger, L. David; Ng, Cliff; Tsai, Miaw-Sheue; Yannone, Steven M.; Tainer, John A.; Campisi, Judith; Cooper, Priscilla K.

    2011-04-20

    XPG is a structure-specific endonuclease required for nucleotide excision repair (NER). XPG incision defects result in the cancer-prone syndrome xeroderma pigmentosum, whereas truncating mutations of XPG cause the severe postnatal progeroid developmental disorder Cockayne syndrome. We show that XPG interacts directly with WRN protein, which is defective in the premature aging disorder Werner syndrome, and that the two proteins undergo similar sub-nuclear redistribution in S-phase and co-localize in nuclear foci. The co-localization was observed in mid- to late-S-phase, when WRN moves from nucleoli to nuclear foci that have been shown to contain protein markers of both stalled replication forks and telomeric proteins. We mapped the interaction between XPG and WRN to the C-terminal domains of each and show that interaction with the C-terminal domain of XPG strongly stimulates WRN helicase activity. WRN also possesses a competing DNA single-strand annealing activity that, combined with unwinding, has been shown to coordinate regression of model replication forks to form Holliday junction/chicken foot intermediate structures. We tested whether XPG stimulated WRN annealing activity and found that XPG itself has intrinsic strand annealing activity that requires the unstructured R- and C-terminal domains, but not the conserved catalytic core or endonuclease activity. Annealing by XPG is cooperative, rather than additive, with WRN annealing. Taken together, our results suggest a novel function for XPG in S-phase that is at least in part carried out coordinately with WRN, and which may contribute to the severity of the phenotypes that occur upon loss of XPG.

  12. Endovascular Aortic Aneurysm Repair with the Talent Stent-Graft: Outcomes in Patients with Large Iliac Arteries

    SciTech Connect (OSTI)

    England, Andrew; Butterfield, John S.; McCollum, Charles N.; Ashleigh, Raymond J.

    2008-07-15

    The purpose of this study is to report outcomes following endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA) in patients with ectatic common iliac arteries (CIAs). Of 117 AAA patients treated by EVAR between 1998 and 2005, 87 (74%) had CIAs diameters <18 mm and 30 (26%) patients had one or more CIA diameters >18 but <25 mm. All patients were treated with Talent stent-grafts, 114 bifurcated and 3 AUI devices. Departmental databases and patient records were reviewed to assess outcomes. Technical success, iliac-related outcome, and iliac-related reintervention (IRSI) were analyzed. Patients with EVAR extending into the external iliac artery were excluded. Median (range) follow-up for the study group was 24 (1-84) months. Initial technical success was 98% for CIAs <18 mm and 100% for CIAs {>=}18 mm (p = 0.551). There were three distal type I endoleaks (two in the ectatic group) and six iliac limb occlusions (one in an ectatic patient); there were no statistically significant differences between groups (p = 0.4). There were nine IRSIs (three stent-graft extensions, six femorofemoral crossover grafts); three of these patients had one or both CIAs {>=}18 mm (p = 0.232). One-year freedom from IRSI was 92% {+-} 3% and 84% {+-} 9% for the <18-mm and {>=}18-mm CIA groups, respectively (p = 0.232). We conclude that the treatment of AAA by EVAR in patients with CIAs 18-24 mm appears to be safe and effective, however, it may be associated with more frequent reinterventions.

  13. Mars Rover's ChemCam Instrument gets sharper vision

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    aboard the Curiosity Rover during NASA's current Mars Mission. Yellowjacket is the first rock targeted by ChemCam after checkout of the auto-focus repair. It is a layered...

  14. Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.

    SciTech Connect (OSTI)

    Tsutakawa, Susan E.; Shin, David S.; Mol, Clifford D.; Izum, Tadahide; Arvai, Andrew S.; Mantha, Anil K.; Szczesny, Bartosz; Ivanov, Ivaylo N.; Hosfield, David J.; Maiti, Buddhadev; Pique, Mike E.; Frankel, Kenneth A.; Hitomi, Kenichi; Cunningham, Richard P.; Mitra, Sankar; Tainer, John A.

    2013-03-22

    Non-coding apurinic/apyrimidinic (AP) sites in DNA form spontaneously and as DNA base excision repair intermediates are the most common toxic and mutagenic in vivo DNA lesion. For repair, AP sites must be processed by 5' AP endonucleases in initial stages of base repair. Human APE1 and bacterial Nfo represent the two conserved 5' AP endonuclease families in the biosphere; they both recognize AP sites and incise the phosphodiester backbone 5' to the lesion, yet they lack similar structures and metal ion requirements. Here, we determined and analyzed crystal structures of a 2.4 ? resolution APE1-DNA product complex with Mg(2+) and a 0.92 Nfo with three metal ions. Structural and biochemical comparisons of these two evolutionarily distinct enzymes characterize key APE1 catalytic residues that are potentially functionally similar to Nfo active site components, as further tested and supported by computational analyses. We observe a magnesium-water cluster in the APE1 active site, with only Glu-96 forming the direct protein coordination to the Mg(2+). Despite differences in structure and metal requirements of APE1 and Nfo, comparison of their active site structures surprisingly reveals strong geometric conservation of the catalytic reaction, with APE1 catalytic side chains positioned analogously to Nfo metal positions, suggesting surprising functional equivalence between Nfo metal ions and APE1 residues. The finding that APE1 residues are positioned to substitute for Nfo metal ions is supported by the impact of mutations on activity. Collectively, the results illuminate the activities of residues, metal ions, and active site features for abasic site endonucleases.

  15. Investigations of DNA damage induction and repair resulting from cellular exposure to high dose-rate pulsed proton beams

    SciTech Connect (OSTI)

    Renis, M.; Malfa, G.; Tomasello, B.; Borghesi, M.; Schettino, G.; Favetta, M.; Romano, F.; Cirrone, G. A. P.; Manti, L.

    2013-07-26

    Studies regarding the radiobiological effects of low dose radiation, microbeam irradiation services have been developed in the world and today laser acceleration of protons and heavy ions may be used in radiation therapy. The application of different facilities is essential for studying bystander effects and relating signalling phenomena in different cells or tissues. In particular the use of ion beams results advantageous in cancer radiotherapy compared to more commonly used X-rays, since the ability of ions in delivering lethal amount of doses into the target tumour avoiding or limiting damage to the contiguous healthy tissues. At the INFN-LNS in Catania, a multidisciplinary radiobiology group is strategically structured aimed to develop radiobiological research, finalised to therapeutic applications, compatible with the use of high dose laser-driven ion beams. The characteristic non-continuous dose rates with several orders of magnitude of laser-driven ion beams makes this facility very interesting in the cellular systems' response to ultra-high dose rates with non-conventional pulse time intervals cellular studies. Our group have projected to examine the effect of high dose laser-driven ion beams on two cellular types: foetal fibroblasts (normal control cells) and DU145 (prostate cancer cells), studying the modulation of some different bio-molecular parameters, in particular cell proliferation and viability, DNA damage, redox cellular status, morphological alterations of both the cytoskeleton components and some cell organelles and the possible presence of apoptotic or necrotic cell death. Our group performed preliminary experiments with high energy (60 MeV), dose rate of 10 Gy/min, doses of 1, 2, 3 Gy and LET 1 keV/?m on human foetal fibroblasts (control cells). We observed that cell viability was not influenced by the characteristics of the beam, the irradiation conditions or the analysis time. Conversely, DNA damage was present at time 0, immediately following irradiation in a dose-dependent manner. The analysis of repair capability showed that the cells irradiated with 1 and 2 Gy almost completely recovered from the damage, but not, however, 3 Gy treated cells in which DNA damage was not recovered. In addition, the results indicate the importance of the use of an appropriate control in radiobiological in vitro analysis.

  16. Haier Repair Confusion Resolved

    Broader source: Energy.gov [DOE]

    On January 7, 2010, DOE entered into a Consent Decree with Haier America regarding a problem with four models of Haier freezers that resulted in those freezers not achieving their advertised energy...

  17. Motor Repair Tech Brief

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Commonly caused by capacitor switching, lightning, or cable standing waves from a variable frequency drive (VFD). These tend to cause turn-to-turn insulation failures. * ...

  18. Remote repair appliance

    DOE Patents [OSTI]

    Heumann, Frederick K.; Wilkinson, Jay C.; Wooding, David R.

    1997-01-01

    A remote appliance for supporting a tool for performing work at a worksite on a substantially circular bore of a workpiece and for providing video signals of the worksite to a remote monitor comprising: a baseplate having an inner face and an outer face; a plurality of rollers, wherein each roller is rotatably and adjustably attached to the inner face of the baseplate and positioned to roll against the bore of the workpiece when the baseplate is positioned against the mouth of the bore such that the appliance may be rotated about the bore in a plane substantially parallel to the baseplate; a tool holding means for supporting the tool, the tool holding means being adjustably attached to the outer face of the baseplate such that the working end of the tool is positioned on the inner face side of the baseplate; a camera for providing video signals of the worksite to the remote monitor; and a camera holding means for supporting the camera on the inner face side of the baseplate, the camera holding means being adjustably attached to the outer face of the baseplate. In a preferred embodiment, roller guards are provided to protect the rollers from debris and a bore guard is provided to protect the bore from wear by the rollers and damage from debris.

  19. Remote repair appliance

    DOE Patents [OSTI]

    Heumann, F.K.; Wilkinson, J.C.; Wooding, D.R.

    1997-12-16

    A remote appliance for supporting a tool for performing work at a work site on a substantially circular bore of a work piece and for providing video signals of the work site to a remote monitor comprises: a base plate having an inner face and an outer face; a plurality of rollers, wherein each roller is rotatably and adjustably attached to the inner face of the base plate and positioned to roll against the bore of the work piece when the base plate is positioned against the mouth of the bore such that the appliance may be rotated about the bore in a plane substantially parallel to the base plate; a tool holding means for supporting the tool, the tool holding means being adjustably attached to the outer face of the base plate such that the working end of the tool is positioned on the inner face side of the base plate; a camera for providing video signals of the work site to the remote monitor; and a camera holding means for supporting the camera on the inner face side of the base plate, the camera holding means being adjustably attached to the outer face of the base plate. In a preferred embodiment, roller guards are provided to protect the rollers from debris and a bore guard is provided to protect the bore from wear by the rollers and damage from debris. 5 figs.

  20. Glenn Powell | Bioenergy | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Glenn Powell Glenn Powell Renewable Energy Research Technician Glenn.Powell@nrel.gov | 303-384-6182 Areas of Expertise Research-focused mechanical support, design, installation, operation, repair Fabrication, welding, TIG, MIG, arc, gas, steel, stainless steel, aluminum, copper Machining, milling, drilling, lathe turning Complex laboratory plumbing, flow control, filtration, design Design, drawing, AutoCAD, AutoCAD 3D, P&ID Electrical, installation, fault finding, repair, safety awareness

  1. Pharmacogenetic Study in Rectal Cancer Patients Treated With Preoperative Chemoradiotherapy: Polymorphisms in Thymidylate Synthase, Epidermal Growth Factor Receptor, GSTP1, and DNA Repair Genes

    SciTech Connect (OSTI)

    Paez, David; Salazar, Juliana; Pare, Laia; Pertriz, Lourdes; Targarona, Eduardo; Rio, Elisabeth del; Barnadas, Agusti; Marcuello, Eugenio; Baiget, Montserrat

    2011-12-01

    Purpose: Several studies have been performed to evaluate the usefulness of neoadjuvant treatment using oxaliplatin and fluoropyrimidines for locally advanced rectal cancer. However, preoperative biomarkers of outcome are lacking. We studied the polymorphisms in thymidylate synthase, epidermal growth factor receptor, glutathione S-transferase pi 1 (GSTP1), and several DNA repair genes to evaluate their usefulness as pharmacogenetic markers in a cohort of 128 rectal cancer patients treated with preoperative chemoradiotherapy. Methods and Materials: Blood samples were obtained from 128 patients with Stage II-III rectal cancer. DNA was extracted from the peripheral blood nucleated cells, and the genotypes were analyzed by polymerase chain reaction amplification and automated sequencing techniques or using a 48.48 dynamic array on the BioMark system. The germline polymorphisms studied were thymidylate synthase, (VNTR/5 Prime UTR, 2R G>C single nucleotide polymorphism [SNP], 3R G>C SNP), epidermal growth factor receptor (Arg497Lys), GSTP1 (Ile105val), excision repair cross-complementing 1 (Asn118Asn, 8092C>A, 19716G>C), X-ray repair cross-complementing group 1 (XRCC1) (Arg194Trp, Arg280His, Arg399Gln), and xeroderma pigmentosum group D (Lys751Gln). The pathologic response, pathologic regression, progression-free survival, and overall survival were evaluated according to each genotype. Results: The Asterisk-Operator 3/ Asterisk-Operator 3 thymidylate synthase genotype was associated with a greater response rate (pathologic complete remission and microfoci residual tumor, 59% in Asterisk-Operator 3/ Asterisk-Operator 3 vs. 35% in Asterisk-Operator 2/ Asterisk-Operator 2 and Asterisk-Operator 2/ Asterisk-Operator 3; p = .013). For the thymidylate synthase genotype, the median progression-free survival was 103 months for the Asterisk-Operator 3/ Asterisk-Operator 3 patients and 84 months for the Asterisk-Operator 2/ Asterisk-Operator 2 and Asterisk-Operator 2/ Asterisk-Operator 3 patients (p = .039). For XRCC1 Arg399Gln SNP, the median progression-free survival was 101 months for the G/G, 78 months for the G/A, and 31 months for the A/A patients (p = .048). Conclusions: The thymidylate synthase genotype and XRCC1 Arg399Gln polymorphism might help to identify Stage II-III rectal cancer patients with a better outcome after preoperative concomitant chemoradiotherapy.

  2. Low Dose Radiation-Induced Genome and Epigenome Instability Symposium and Epigenetic Mechanisms, DNA Repair, and Chromatin Symposium at the EMS 2008 Annual Meeting - October 2008

    SciTech Connect (OSTI)

    Morgan, William F.; Kovalchuk, Olga; Dolinoy, Dana C.; Dubrova, Yuri E.; Coleman, Matthew A.; Schär, Primo; Pogribny, Igor; Hendzel, Michael

    2010-02-19

    The Low Dose Radiation Symposium thoughtfully addressed ionizing radiation non-mutational but transmissable alterations in surviving cells. Deregulation of epigenetic processes has been strongly implicated in carcinogenesis, and there is increasing realization that a significant fraction of non-targeted and adaptive mechanisms in response to ionizing radiation are likely to be epigenetic in nature. Much remains to be learned about how chromatin and epigenetic regulators affect responses to low doses of radiation, and how low dose radiation impacts other epigenetic processes. The Epigenetic Mechanisms Symposium focused on on epigenetic mechanisms and their interplay with DNA repair and chromatin changes. Addressing the fact that the most well understood mediators of epigenetic regulation are histone modifications and DNA methylation. Low levels of radiation can lead to changes in the methylation status of certain gene promoters and the expression of DNA methyltransferases, However, epigenetic regulation can also involve changes in higher order chromosome structure.

  3. Lumens: The new way to shop for light

    Energy Savers [EERE]

    Gas Heat Pump For Building Space Heating Low-Cost Gas Heat Pump For Building Space Heating Credit: Stone Mountain Technologies Credit: Stone Mountain Technologies Lead Performer: Stone Mountain Technologies - Erwin, TN Partners: -- A.O. Smith - Milwaukee, WI -- Gas Technology Institute - Des Plaines, IL DOE Funding: $903,000 Cost Share: $232,294 Project Term: 3/1/2013 - 2/28/2015 Funding Opportunity: Energy Savings Through Improved Mechanical Systems and Building Envelope Technologies 2012

  4. Cosmologist's tour through the new particle zoo (candy shop)

    SciTech Connect (OSTI)

    Turner, M.S.

    1986-01-01

    Recent developments in elementary particle physics have led to a renaissance in cosmology, in general, and in the study of structure formation, in particular. Already, the study of the very early (t less than or equal to 10/sup -2/ sec) history of the Universe has provided valuable hints as to the 'initial data' for the structure formation problem - the nature and origin of the primeval density inhomogeneities, the quantity and composition of matter in the Universe today, and numerous candidates for the constituents of the ubiquitious dark matter. I review the multitude of WIMP candidates for the dark matter provided by modern particle physics theories, putting them into context by briefly discussing the theories which predict them. I also review their various birth sites and birth processes in the early Universe. At present the most promising candidates seem to be a 30 or so eV neutrino, a few GeV photino, or the 'invisible axion' (weighing in at about 10/sup -5/ eV), with a planck mass monopole, quark nuggets, and shadow matter as the leading 'dark' horse candidates. I also mention some very exotic possibilities - unstable WIMPs, cosmic strings, and even the possibility of a relic cosmological term.

  5. Post-Holiday Holiday Shopping | Department of Energy

    Energy Savers [EERE]

    Post Office Building, Rancho Mirage, California Post Office Building, Rancho Mirage, California Photo of Photovoltaic System at Rancho Mirage Post Office in California The U.S. Postal Service (USPS) has been making an effort to add solar power to its offices as part of the Million Solar Roofs Initiative. They have been working with the staff at the National Renewable Energy Laboratory (NREL) to implement energy systems at USPS facilities. NREL assisted the USPS in rehabilitating an inoperable

  6. ProteinShop: A Tool for Interactive Protein

    Office of Scientific and Technical Information (OSTI)

    ... Dictionary of protein secondary structures: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 22 (1983). 19. C. Welman. Inverse kinematics and geometric ...

  7. Biomass Company Sets Up Shop in High School Lab

    Broader source: Energy.gov [DOE]

    Unlike most biotechnology students who have to go to a research facility to see scientists in action, those at Greeneville High just need to turn their heads.

  8. How Will You Shop for Your Next Vehicle?

    Broader source: Energy.gov [DOE]

    Are you starting to research vehicles, and if so, what tools are you using to help you make a decision?

  9. Standard-E hydrogen monitoring system shop acceptance test procedure

    SciTech Connect (OSTI)

    Schneider, T.C.

    1997-10-02

    The purpose of this report is to document that the Standard-E Hydrogen Monitoring Systems (SHMS-E), fabricated by Mid-Columbia Engineering (MCE) for installation on the Waste Tank Farms in the Hanford 200 Areas, are constructed as intended by the design. The ATP performance will verify proper system fabrication.

  10. DockingShop: A Tool for Interactive Molecular Docking (Conference...

    Office of Scientific and Technical Information (OSTI)

    Its output--the structure of aprotein-ligand or protein-protein complex--may serve as an input for aprotein docking algorithm, or an optimization process. This tool provides ...

  11. Oxidative DNA damage and repair in children exposed to low levels of arsenic in utero and during early childhood: Application of salivary and urinary biomarkers

    SciTech Connect (OSTI)

    Hinhumpatch, Pantip; Navasumrit, Panida; Chaisatra, Krittinee; Promvijit, Jeerawan; Mahidol, Chulabhorn; Ruchirawat, Mathuros

    2013-12-15

    The present study aimed to assess arsenic exposure and its effect on oxidative DNA damage and repair in young children exposed in utero and continued to live in arsenic-contaminated areas. To address the need for biological specimens that can be acquired with minimal discomfort to children, we used non-invasive urinary and salivary-based assays for assessing arsenic exposure and early biological effects that have potentially serious health implications. Levels of arsenic in nails showed the greatest magnitude of difference between exposed and control groups, followed by arsenic concentrations in saliva and urine. Arsenic levels in saliva showed significant positive correlations with other biomarkers of arsenic exposure, including arsenic accumulation in nails (r = 0.56, P < 0.001) and arsenic concentration in urine (r = 0.50, P < 0.05). Exposed children had a significant reduction in arsenic methylation capacity indicated by decreased primary methylation index and secondary methylation index in both urine and saliva samples. Levels of salivary 8-OHdG in exposed children were significantly higher (? 4-fold, P < 0.01), whereas levels of urinary 8-OHdG excretion and salivary hOGG1 expression were significantly lower in exposed children (? 3-fold, P < 0.05), suggesting a defect in hOGG1 that resulted in ineffective cleavage of 8-OHdG. Multiple regression analysis results showed that levels of inorganic arsenic (iAs) in saliva and urine had a significant positive association with salivary 8-OHdG and a significant negative association with salivary hOGG1 expression. - Highlights: The effects of arsenic exposure in utero and through early childhood were studied. Arsenic-exposed children had a reduction in arsenic methylation capacity. Exposed children had more DNA damage, observed as elevated salivary 8-OHdG. Lower salivary hOGG1 in exposed children indicated impairment of 8-OHdG repair. Salivary and urinary 8-OHdG levels were discordant.

  12. Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Cunniffe, Siobhan; O’Neill, Peter; Greenberg, Marc M.; Lomax, Martine E.

    2014-04-01

    A signature of ionizing radiation is the induction of DNA clustered damaged sites. Non-double strand break (DSB) clustered damage has been shown to compromise the base excision repair pathway, extending the lifetimes of the lesions within the cluster, compared to isolated lesions. This increases the likelihood the lesions persist to replication and thus increasing the mutagenic potential of the lesions within the cluster. Lesions formed by ionizing radiation include 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) and 2-deoxyribonolactone (dL). dL poses an additional challenge to the cell as it is not repaired by the short-patch base excision repair pathway. Here we show recalcitrant dL repairmore » is reflected in mutations observed when DNA containing it and a proximal 8-oxodGuo is replicated in Escherichia coli. 8-oxodGuo in close proximity to dL on the opposing DNA strand results in an enhanced frequency of mutation of the lesions within the cluster and a 20 base sequence flanking the clustered damage site in an E. coli based plasmid assay. In vitro repair of a dL lesion is reduced when compared to the repair of an abasic (AP) site and a tetrahydrofuran (THF), and this is due mainly to a reduction in the activity of polymerase β, leading to retarded FEN1 and ligase 1 activities. This study has given insights in to the biological effects of clusters containing dL.« less

  13. Lead exposure among small-scale battery recyclers, automobile radiator mechanics, and their children in Manila, the Philippines

    SciTech Connect (OSTI)

    Suplido, M.L.; Ong, C.N.

    2000-03-01

    Blood lead (PbB) and hemoglobin levels (Hb) were determined in 40 battery repair/recycling shop workers, 16 radiator repair shop workers, and 20 children living in the immediate vicinity of these shops. Unexposed residents with similar socio-economic status were also investigated. Mean PbB level was significantly higher for battery workers when compared to radiator workers and unexposed adults. Among battery workers, 94% had PbB levels above the WHO permissible exposure limit of 40 {micro}g/dL for males and 30 {micro}g/dL for females. There was no demarcation between workplace and living quarters; therefore, workers' families were similarly exposed to hazards. Children living in the immediate vicinity of battery shops also had significantly higher mean PbB levels compared to radiator shop children and unexposed children. For workers with PbB > 40 {micro}g/dL, 90% were anemic. Linear regression showed a correlation between Hb level and log{sub 10}PbB. There was no significant relationship between anemia and blood lead in children. The authors conclude that radiator repair activities appeared to increase the body burden of lead, although not up to a level significantly different from unexposed counterparts. Battery recycling/repair activities, however, significantly increased blood lead levels in workers and their children.

  14. Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

    SciTech Connect (OSTI)

    Chen, Xi; Ballin, Jeff D.; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J.; Tomkinson, Alan E.; Wilson, Gerald M.

    2009-05-11

    The three human LIG genes encode polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination and repair. While numerous studies have identified protein partners of the human DNA ligases (hLigs), there has been little characterization of the catalytic properties of these enzymes. In this study, we developed and optimized a fluorescence-based DNA ligation assay to characterize the activities of purified hLigs. Although hLigI joins DNA nicks, it has no detectable activity on linear duplex DNA substrates with short, cohesive single-strand ends. By contrast, hLigIII{beta} and the hLigIII{alpha}/XRCC1 and hLigIV/XRCC4 complexes are active on both nicked and linear duplex DNA substrates. Surprisingly, hLigIV/XRCC4, which is a key component of the major non-homologous end joining (NHEJ) pathway, is significantly less active than hLigIII on a linear duplex DNA substrate. Notably, hLigIV/XRCC4 molecules only catalyze a single ligation event in the absence or presence of ATP. The failure to catalyze subsequent ligation events reflects a defect in the enzyme-adenylation step of the next ligation reaction and suggests that, unless there is an in vivo mechanism to reactivate DNA ligase IV/XRCC4 following phosphodiester bond formation, the cellular NHEJ capacity will be determined by the number of adenylated DNA ligaseIV/XRCC4 molecules.

  15. Secretary Moniz's Remarks at the Washington Auto Show -- As Delivered...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... These long-haul trucks consume about 20 percent of all vehicle fuel in the United States, so a wide adoption of these technologies is talking in the range of tens of billions of ...

  16. Auto industry steel project to boost efficiency, safety

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Partitioning Process Development to Replace Hot Stamping of High Strength Automotive Steel," is led by CSM Metallurgical and Materials Engineering Professor Emmanuel De Moor,...

  17. SLIDESHOW: Secretary Moniz Tours 2014 Washington Auto Show |...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Based on results from laboratory tests, the Energy Department predicts that the fuel economy for internal combustion engine passenger vehicles can be further improved by more than ...

  18. Auto/Steel Partnership: Fatigue of AHSS Strain Rate Characterization

    Broader source: Energy.gov [DOE]

    2009 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C.

  19. Secretary Chu Visits the 2012 North American International Auto...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... The visit gave the Secretary a glimpse at what's on the horizon for American automobiles as well as the opportunity to observe how technological innovations like the ones developed ...

  20. Secretary Chu's Remarks for an Auto Loan Announcement in Michigan...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... more than a dozen popular models, including the Focus, the Escape, the Taurus and the F-150. Ford will transform nearly 35,000 jobs into "green" engineering and manufacturing jobs. ...

  1. Obama Administration Awards First Three Auto Loans for Advanced...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    models; 1.6 billion to Nissan North America, Inc. to retool their Smyrna, Tennessee factory to build advanced electric automobiles and to build an advanced battery manufacturing ...

  2. A Look Inside the Detroit Auto Show | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the power of a 563-horsepower V-8 engine and a dual inertial flywheel system to ... building energy efficiency Among other biofuel vehicles, Swedish Biogas had their ...

  3. 2015 UTSR Poster Presentations Prediction of Auto-Ignition Regimes...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bond Coats for Thermal Barrier Coating Systems Based on High Entropy Alloys Derek Hass, DVTI Autoignition of a Jet-A Spray in a Hot, Vitiated Air Flow Aimee Williams, Georgia...

  4. Interested Parties - United Auto Workers | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    UAW.pdf More Documents & Publications Interested Parties - BlueGreen Alliance Interested Parties - Myriant Interested Parties - NRG Energy

  5. Energy Department Offers $50 Million to Advance Fuel Efficient Autos

    Broader source: Energy.gov [DOE]

    The Energy Department announced nearly $50 million to accelerate research and development of new vehicle technologies that give drivers and businesses more transportation options and protect the environment in communities nationwide.

  6. Photo of the Week: the 2014 Washington Auto Show | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sarah Gerrity Sarah Gerrity Former Multimedia Editor, Office of Public Affairs Every week, we'll feature our favorite energy-related photo here on Energy.gov, at Facebook.com...

  7. Arkansan Worker Cuts Bills After Auto Job Layoff

    Broader source: Energy.gov [DOE]

    His low income qualified him for Recovery Act-funded hone weatherization, making a big impact on his energy bills.

  8. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    Broader source: Energy.gov [DOE]

    In Dearborn, Michigan Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of...

  9. Auto shredder residue recycling: Mechanical separation and pyrolysis

    SciTech Connect (OSTI)

    Santini, Alessandro; Passarini, Fabrizio; Vassura, Ivano; Serrano, David; Dufour, Javier

    2012-05-15

    Highlights: Black-Right-Pointing-Pointer In this work, we exploited mechanical separation and pyrolysis to recycle ASR. Black-Right-Pointing-Pointer Pyrolysis of the floating organic fraction is promising in reaching ELV Directive targets. Black-Right-Pointing-Pointer Zeolite catalyst improve pyrolysis oil and gas yield. - Abstract: sets a goal of 85% material recycling from end-of-life vehicles (ELVs) by the end of 2015. The current ELV recycling rate is around 80%, while the remaining waste is called automotive shredder residue (ASR), or car fluff. In Europe, this is mainly landfilled because it is extremely heterogeneous and often polluted with car fluids. Despite technical difficulties, in the coming years it will be necessary to recover materials from car fluff in order to meet the ELV Directive requirement. This study deals with ASR pretreatment and pyrolysis, and aims to determine whether the ELV material recycling target may be achieved by car fluff mechanical separation followed by pyrolysis with a bench scale reactor. Results show that flotation followed by pyrolysis of the light, organic fraction may be a suitable ASR recycling technique if the oil can be further refined and used as a chemical. Moreover, metals are liberated during thermal cracking and can be easily separated from the pyrolysis char, amounting to roughly 5% in mass. Lastly, pyrolysis can be a good starting point from a 'waste-to-chemicals' perspective, but further research should be done with a focus on oil and gas refining, in order both to make products suitable for the chemical industry and to render the whole recycling process economically feasible.

  10. Auto Indexer for Percussive Hammers | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    keyboard-621831_960_720.jpg The Authorizing Official (AO) is the Senior Federal DOE management official with the authority to assume responsibility for operating an information system at an acceptable level of risk. PDF icon AO Energy

    student-849822_960_720.jpg The Authorizing Official Designated Representative (AODR) provides technical and organizational support to the Authorizing Official (AO). Individual(s) in the AO Representative role must possess a working knowledge of: system

  11. Former Auto Worker Gauges Efficiency of American Homes

    Broader source: Energy.gov [DOE]

    Holland, Michigan resident retools skills learned testing car parts to land new job assessing home energy efficiency as a weatherization inspector.

  12. Acute Normal Tissue Reactions in Head-and-Neck Cancer Patients Treated With IMRT: Influence of Dose and Association With Genetic Polymorphisms in DNA DSB Repair Genes

    SciTech Connect (OSTI)

    Werbrouck, Joke Ruyck, Kim de; Duprez, Frederic; Veldeman, Liv; Claes, Kathleen; Eijkeren, Marc van; Boterberg, Tom; Willems, Petra; Vral, Anne; Neve, Wilfried de; Thierens, Hubert

    2009-03-15

    Purpose: To investigate the association between dose-related parameters and polymorphisms in DNA DSB repair genes XRCC3 (c.-1843A>G, c.562-14A>G, c.722C>T), Rad51 (c.-3429G>C, c.-3392G>T), Lig4 (c.26C>T, c.1704T>C), Ku70 (c.-1310C>G), and Ku80 (c.2110-2408G>A) and the occurrence of acute reactions after radiotherapy. Materials and Methods: The study population consisted of 88 intensity-modulated radiation therapy (IMRT)-treated head-and-neck cancer patients. Mucositis, dermatitis, and dysphagia were scored using the Common Terminology Criteria (CTC) for Adverse Events v.3.0 scale. The population was divided into a CTC0-2 and CTC3+ group for the analysis of each acute effect. The influence of the dose on critical structures was analyzed using dose-volume histograms. Genotypes were determined by polymerase chain reaction (PCR) combined with restriction fragment length polymorphism or PCR-single base extension assays. Results: The mean dose (D{sub mean}) to the oral cavity and constrictor pharyngeus (PC) muscles was significantly associated with the development of mucositis and dysphagia, respectively. These parameters were considered confounding factors in the radiogenomics analyses. The XRCC3c.722CT/TT and Ku70c.-1310CG/GG genotypes were significantly associated with the development of severe dysphagia (CTC3+). No association was found between the investigated polymorphisms and the development of mucositis or dermatitis. A risk analysis model for severe dysphagia, which was developed based on the XRCC3c.722CT/TT and Ku70c.-1310CG/GG genotypes and the PC dose, showed a sensitivity of 78.6% and a specificity of 77.6%. Conclusions: The XRCC3c.722C>T and Ku70c.-1310C>G polymorphisms as well as the D{sub mean} to the PC muscles were highly associated with the development of severe dysphagia after IMRT. The prediction model developed using these parameters showed a high sensitivity and specificity.

  13. Functional Polymorphisms of Base Excision Repair Genes XRCC1 and APEX1 Predict Risk of Radiation Pneumonitis in Patients With Non-Small Cell Lung Cancer Treated With Definitive Radiation Therapy

    SciTech Connect (OSTI)

    Yin Ming; Liao Zhongxing; Liu Zhensheng; Wang, Li-E; Gomez, Daniel; Komaki, Ritsuko; Wei Qingyi

    2011-11-01

    Purpose: To explore whether functional single nucleotide polymorphisms (SNPs) of base-excision repair genes are predictors of radiation treatment-related pneumonitis (RP), we investigated associations between functional SNPs of ADPRT, APEX1, and XRCC1 and RP development. Methods and Materials: We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs25489 [R280H], and rs25487 [Q399R]), and APEX1 (rs1130409 [D148E]) in 165 patients with non-small cell lung cancer (NSCLC) who received definitive chemoradiation therapy. Results were assessed by both Logistic and Cox regression models for RP risk. Kaplan-Meier curves were generated for the cumulative RP probability by the genotypes. Results: We found that SNPs of XRCC1 Q399R and APEX1 D148E each had a significant effect on the development of Grade {>=}2 RP (XRCC1: AA vs. GG, adjusted hazard ratio [HR] = 0.48, 95% confidence interval [CI], 0.24-0.97; APEX1: GG vs. TT, adjusted HR = 3.61, 95% CI, 1.64-7.93) in an allele-dose response manner (Trend tests: p = 0.040 and 0.001, respectively). The number of the combined protective XRCC1 A and APEX1 T alleles (from 0 to 4) also showed a significant trend of predicting RP risk (p = 0.001). Conclusions: SNPs of the base-excision repair genes may be biomarkers for susceptibility to RP. Larger prospective studies are needed to validate our findings.

  14. Erosion Flume | Open Energy Information

    Open Energy Info (EERE)

    Real-Time Yes Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop, carpenter shop, welding shop, instrumentation and electronics shop Past...

  15. Kennedy Flume | Open Energy Information

    Open Energy Info (EERE)

    Real-Time Yes Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop, carpenter shop, welding shop, instrumentation and electronics shop Past...

  16. Environmental Flume | Open Energy Information

    Open Energy Info (EERE)

    Real-Time Yes Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop, carpenter shop, welding shop, instrumentation and electronics shop Past...

  17. University of Iowa Wave Basin | Open Energy Information

    Open Energy Info (EERE)

    Real-Time Yes Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop, carpenter shop, welding shop, instrumentation and electronics shop Past...

  18. Ice Towing Tank | Open Energy Information

    Open Energy Info (EERE)

    Real-Time Yes Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop, carpenter shop, welding shop, instrumentation and electronics shop Past...

  19. Small Towing Tank | Open Energy Information

    Open Energy Info (EERE)

    Real-Time Yes Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop, carpenter shop, welding shop, instrumentation and electronics shop Past...

  20. Microsoft Word - Interim Work Authorization Form rev 2-9.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rev. 2/9/05 * Submit original form to M. Montalvo, MS 69, promptly on completion of work. INTERIM Work Authorization Process for Activities by Non-SSRL Workers at SSRL This Work Authorization Process applies to all maintenance, repair, and installation work performed at SSRL by non-SSRL workers. All work must be initiated by a technically qualified SSRL staff person (e.g. accelerator system manager, shop manager, facilities staff member, beam line engineer, etc.) who will serve as the

  1. Shopping For Danger: E-commerce techniques applied to collaboration in cyber security

    SciTech Connect (OSTI)

    Bruce, Joseph R.; Fink, Glenn A.

    2012-05-24

    Collaboration among cyber security analysts is essential to a successful protection strategy on the Internet today, but it is uncommonly practiced or encouraged in operating environments. Barriers to productive collaboration often include data sensitivity, time and effort to communicate, institutional policy, and protection of domain knowledge. We propose an ambient collaboration framework, Vulcan, designed to remove the barriers of time and effort and mitigate the others. Vulcan automated data collection, collaborative filtering, and asynchronous dissemination, eliminating the effort implied by explicit collaboration among peers. We instrumented two analytic applications and performed a mock analysis session to build a dataset and test the output of the system.

  2. Farmer owned multi-use solar buildings for drying hay, grain, or heating shop

    SciTech Connect (OSTI)

    DeBusk, K.E.

    1983-06-01

    Identical multi-use solar buildings were built and tested on two farms in 1982. Actual (not simple) pay back periods are given for the two buildings for hay and for grain drying. Comparisons between solar and computed propane gas costs are reported.

  3. Energy Efficiency Can Be at the Top of Your Shopping List | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    list, too. Plug-in hybrid - Electric cars with some serious potential, the lithium ion battery-powered go-getters should be available next year or in 2011, including ones from...

  4. Energy Efficiency Can Be at the Top of Your Shopping List

    Broader source: Energy.gov [DOE]

    I hope your holidays are filled with cool ways to fine-tune your life that will get you closer to the cutting edge of energy efficiency.

  5. Energy Savers: A one-stop energy efficiency shop for multifamily building owners

    Broader source: Energy.gov [DOE]

    This is a document from Energy Impact Illinois posted on the website of U.S. Department of Energy's Better Buildings Neighborhood Program.

  6. Electricity rate effects of 150 MW shop assembled turbocharged boiler generating units

    SciTech Connect (OSTI)

    Drenker, S.; Fancher, R.

    1984-08-01

    Major upheavals in the environment in which electric utilities operate began in the 1960's. Modular construction, developed and perfected by process industry engineering firms, in conjuction with small turbocharged boiler power plants (currently under development), can respond to these forces by shortening construction time. Benefits from this approach, resulting from better matching of load growth and reducing planning horizon, can equal 15% to 60% of the capital cost of large pulverized coal plants.

  7. DockingShop: A Tool for Interactive Molecular Docking Ting-Cheng...

    Office of Scientific and Technical Information (OSTI)

    ... determining molecular interactions using visual feedbacks to steer the docking process in ... Our work also advances state-of-the-art computational biology and scientific visualization ...

  8. Measure Guideline: Window Repair, Rehabilitation, and Replacement

    SciTech Connect (OSTI)

    Baker, P.

    2012-12-01

    This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

  9. cx-emergency-levee-repair.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

  10. Repair welding of fusion reactor components

    SciTech Connect (OSTI)

    Chin, B.A.

    1993-05-15

    Experiments have shown that irradiated Type 316 stainless steel is susceptible to heat-affected-zone (HAZ) cracking upon cooling when welded using the gas tungsten arc (GTA) process under lateral constraint. The cracking has been hypothesized to be caused by stress-assisted helium bubble growth and rupture at grain boundaries. This study utilized an experimental welding setup which enabled different compressive stresses to be applied to the plates during welding. Autogenous GTA welds were produced in Type 316 stainless steel doped with 256 appm helium. The application of a compressive stress, 55 MPa, during welding suppressed the previously observed catastrophic cracking. Detailed examinations conducted after welding showed a dramatic change in helium bubble morphology. Grain boundary bubble growth along directions parallel to the weld was suppressed. Results suggest that stress-modified welding techniques may be used to suppress or eliminate helium-induced cracking during joining of irradiated materials.

  11. Selected Bibliography on Electric Motor Repair

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Anderson, Edwin P. and Rex Miller, Electric Motors, 5th Edition, 1991. A comprehensive ... Dreisilker, Henry, "Modern Rewinding Methods Assure Better Rebuilt Motors." EC&M, August ...

  12. Botas line repaired ahead of schedule

    SciTech Connect (OSTI)

    Not Available

    1991-11-01

    This paper reports on damaged sections of Botas' dual 30-in. gas line carrying USSR gas across the Marmara Sea to Turkey that were replaced 30 days ahead of contract schedule. Tefken Construction and Installation Co., Inc., Istanbul, working under a $4-million contract, replaced two sections on one of the dual lines near Ambarli, Turkey, within a two-month period. The offshore system stretches 33-mi under the Marmara Sea with some pipe laid at 262-ft maximum water depths. The scope of the project was to replace a 426-ft offshore approach to the northern shoreline and a 984-ft onshore section, which were damaged by a submarine landslide.

  13. Coiled tubing cuts horizontal screen repair cost

    SciTech Connect (OSTI)

    Crow, W.; Hill, P.; Johnston, R.

    1996-01-01

    This article presents a case history of the successful workover performed by a coiled tubing unit (CTU) on Mississippi Canyon (MC) Block 109 Well A-24 in the US Gulf of Mexico to clean out sand and install new concentric screen for sand control. Workover design and operational details discussed are: Workover design -- hole-cleaning hydraulics, CT and screen predictions and comparison considerations; Workover operations -- cleanout, running packer and screens, coiled tubing (CT) weights, acid treatment and nitrogen lift and flow back.

  14. Secretary Chu to Highlight Administration Support for U.S. Auto...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hansen Clarke for a tour of robotics, chemistry and physics classrooms and labs at ... Hansen Clarke to tour robotics, chemistry and physics classrooms and labs at ...

  15. Auto/Steel Partnership: Hydroforming Materials and Lubricant Lightweight Rear Chassis Structures Future Generation Passenger Compartment

    Broader source: Energy.gov [DOE]

    2009 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C.

  16. Auto/Steel Partnership: Advanced High-Strength Steel Research and Development

    Broader source: Energy.gov [DOE]

    2009 DOE Hydrogen Program and Vehicle Technologies Program Annual Merit Review and Peer Evaluation Meeting, May 18-22, 2009 -- Washington D.C.

  17. Materials, Modules, and Systems: An Atoms to Autos Approach to Automotive Thermoelectric Systems Development

    Broader source: Energy.gov [DOE]

    Highlights comprehensive approach tothermoelectric materials, module, and systems development at GM and in collaboration with our R&D partners

  18. Auto/Steel Partnership: AHSS Stamping, Strain Rate Characterization, Sheet Steel Fatigue, AHSS Joining

    Broader source: Energy.gov [DOE]

    2010 DOE Vehicle Technologies and Hydrogen Programs Annual Merit Review and Peer Evaluation Meeting, June 7-11, 2010 -- Washington D.C.

  19. Modeling the Auto-Ignition of Biodiesel Blends with a Multi-Step Model

    SciTech Connect (OSTI)

    Toulson, Dr. Elisa; Allen, Casey M; Miller, Dennis J; McFarlane, Joanna; Schock, Harold; Lee, Tonghun

    2011-01-01

    There is growing interest in using biodiesel in place of or in blends with petrodiesel in diesel engines; however, biodiesel oxidation chemistry is complicated to directly model and existing surrogate kinetic models are very large, making them computationally expensive. The present study describes a method for predicting the ignition behavior of blends of n-heptane and methyl butanoate, fuels whose blends have been used in the past as a surrogate for biodiesel. The autoignition is predicted using a multistep (8-step) model in order to reduce computational time and make this a viable tool for implementation into engine simulation codes. A detailed reaction mechanism for n-heptane-methyl butanoate blends was used as a basis for validating the multistep model results. The ignition delay trends predicted by the multistep model for the n-heptane-methyl butanoate blends matched well with that of the detailed CHEMKIN model for the majority of conditions tested.

  20. As Auto X Reaches the Finish Line, a New Race Begins

    Broader source: Energy.gov [DOE]

    After two tough years of competition, evaluation and testing -- the winners of the Automotive X Prize are announced.

  1. Method for improving catalyst function in auto-thermal and partial oxidation reformer-based processors

    DOE Patents [OSTI]

    Ahmed, Shabbir; Papadias, Dionissios D.; Lee, Sheldon H.D.; Ahluwalia, Rajesh K.

    2014-08-26

    The invention provides a method for reforming fuel, the method comprising contacting the fuel to an oxidation catalyst so as to partially oxidize the fuel and generate heat; warming incoming fuel with the heat while simultaneously warming a reforming catalyst with the heat; and reacting the partially oxidized fuel with steam using the reforming catalyst.

  2. All auto shredding: evaluation of automotive shredder residue generated by shredding only vehicles.

    SciTech Connect (OSTI)

    Duranceau, C. M.; Spangenberger, J. S.

    2011-09-26

    A well developed infrastructure exists for the reuse and recycling of automotive parts and materials. At the end of a vehicle's useful life many parts are removed and sold for reuse and fluids are recovered for recycling or proper disposal. What remains is shredded, along with other metal bearing scrap such as home appliances, demolition debris and process equipment, and the metals are separated out and recycled. The remainder of the vehicle materials is call shredder residue which ends up in the landfill. As energy and natural resources becomes more treasured, increased effort has been afforded to find ways to reduce energy consumption and minimize the use of our limited resources. Many of the materials found in shredder residue could be recovered and help offset the use of energy and material consumption. For example, the energy content of the plastics and rubbers currently landfilled with the shredder residue is equivalent to 16 million barrels of oil per year. However, in the United States, the recovered materials, primarily polymers, cannot be recycled due to current regulatory barriers which preclude the re-introduction into commerce of certain materials because of residual contamination with substances of concern (SOCs) such as polychlorinated biphenyls (PCBs). The source of the PCBs is not well understood. Old transformers, capacitors, white goods and ballasts from lighting fixtures are likely contributing factors. The project was designed to evaluate whether vehicles of varying age and manufacturing origin contribute to the PCB content in shredder residue. Additionally, the project was designed to determine if there are any trends in material composition of the shredder residue from varied age and manufacturing groups. This information would aid in future material recovery facility strategy and design. The test utilized a newly installed shredder plant to shred four categories of automobiles. The categories were defined by vehicle age and the manufacturing company and location. Each category of vehicles was processed individually through the shredder plant and the resulting shredder residue was analyzed for its materials composition and presence of PCBs and leachable metals. The results show that shredder residue from all vehicle categories tested are not significant contributors of PCBs and leachable metals. It was evident that leachable cadmium levels have decreased in newer vehicles. The composition of the shredder residue from each of the four categories is similar to the others. In addition, these compositions are approximately equal to the composition of typical shredder residues, not limited to automotive materials.

  3. Wide tracking range, auto ranging, low jitter phase lock loop for swept and fixed frequency systems

    DOE Patents [OSTI]

    Kerner, Thomas M.

    2001-01-01

    The present invention provides a wide tracking range phase locked loop (PLL) circuit that achieves minimal jitter in a recovered clock signal, regardless of the source of the jitter (i.e. whether it is in the source or the transmission media). The present invention PLL has automatic harmonic lockout detection circuitry via a novel lock and seek control logic in electrical communication with a programmable frequency discriminator and a code balance detector. (The frequency discriminator enables preset of a frequency window of upper and lower frequency limits to derive a programmable range within which signal acquisition is effected. The discriminator works in combination with the code balance detector circuit to minimize the sensitivity of the PLL circuit to random data in the data stream). In addition, the combination of a differential loop integrator with the lock and seek control logic obviates a code preamble and guarantees signal acquisition without harmonic lockup. An adaptive cable equalizer is desirably used in combination with the present invention PLL to recover encoded transmissions containing a clock and/or data. The equalizer automatically adapts to equalize short haul cable lengths of coaxial and twisted pair cables or wires and provides superior jitter performance itself. The combination of the equalizer with the present invention PLL is desirable in that such combination permits the use of short haul wires without significant jitter.

  4. Process for manufacturing an auto-collimating scintillator and product produced thereby

    DOE Patents [OSTI]

    Goodman, C.A.; Lyon, A.F.; Perez-Mendez, V.

    1995-06-27

    There is described a process for the vapor deposition of a scintillator phosphor composition with concomitant shadowing wherein the substrate to be processed is rotated through an arc relative to a vapor source of the scintillator phosphor composition whereby shadowing introduces voided gaps or interstices between columns as a result of the preferential components receiving more coating flux, particularly in the presence of oblique flux. 8 figs.

  5. Process for manufacturing an auto-collimating scintillator and product produced thereby

    DOE Patents [OSTI]

    Goodman, Claude A.; Lyon, Alan F.; Perez-Mendez, Victor

    1995-01-01

    There is described a process for the vapor deposition of a scintillator phosphor composition with concomitant shadowing wherein the substrate to be processed is rotated through an arc relative to a vapor source of the scintillator phosphor composition whereby shadowing introduces voided gaps or interstices between columns as a result of the preferential components receiving more coating flux, particularly in the presence of oblique flux.

  6. Fact #828: July 7, 2014 Japanese Auto Manufacturers Increase Domestic Production for U.S. Sales

    Broader source: Energy.gov [DOE]

    In 1980, all Japanese-brand vehicles sold in the U.S. were imported. By 1990, just over one-third of Japanese-brand vehicles sold in the U.S. were produced domestically in North America which...

  7. Getting It Right: Accurate Testing and Assessments Critical to Deploying the Next Generation of Auto Fuels

    Broader source: Energy.gov [DOE]

    Today, the Coordinating Research Council released a report on the effects of E15 and E20 on vehicle engines. We, at the Energy Department, believe the study is significantly flawed.

  8. UNIVERSAL AUTO-CALIBRATION FOR A RAPID BATTERY IMPEDANCE SPECTRUM MEASUREMENT DEVICE

    SciTech Connect (OSTI)

    Jon P. Christophersen; John L. Morrison; William H. Morrison

    2014-03-01

    Electrochemical impedance spectroscopy has been shown to be a valuable tool for diagnostics and prognostics of energy storage devices such as batteries and ultra-capacitors. Although measurements have been typically confined to laboratory environments, rapid impedance spectrum measurement techniques have been developed for on-line, embedded applications as well. The prototype hardware for the rapid technique has been validated using lithium-ion batteries, but issues with calibration had also been identified. A new, universal automatic calibration technique was developed to address the identified issues while also enabling a more simplified approach. A single, broad-frequency range is used to calibrate the system and then scaled to the actual range and conditions used when measuring a device under test. The range used for calibration must be broad relative to the expected measurement conditions for the scaling to be successful. Validation studies were performed by comparing the universal calibration approach with data acquired from targeted calibration ranges based on the expected range of performance for the device under test. First, a mid-level shunt range was used for calibration and used to measure devices with lower and higher impedance. Next, a high excitation current level was used for calibration, followed by measurements using lower currents. Finally, calibration was performed over a wide frequency range and used to measure test articles with a lower set of frequencies. In all cases, the universal calibration approach compared very well with results acquired following a targeted calibration. Additionally, the shunts used for the automated calibration technique were successfully characterized such that the rapid impedance measurements compare very well with laboratory-scale measurements. These data indicate that the universal approach can be successfully used for onboard rapid impedance spectra measurements for a broad set of test devices and range of measurement conditions.

  9. Dual-Color Auto-Calibration Scanning-Angle Evanescent Field Microscope...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    that can be used for live cell imaging as well as for examining single molecule dynamics. Total internal reflection fluorescence microscopy (TIRFM) is a mode of...

  10. Mars Rover's ChemCam Instrument gets sharper vision

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mars Rover's ChemCam Instrument gets sharper vision Mars Rover's ChemCam Instrument gets sharper vision NASA's Mars Curiosity Rover's "ChemCam" instrument just got a major capability fix, as Los Alamos National Laboratory scientists uploaded a software repair for the auto-focus system on the instrument. May 21, 2015 SuperCam builds upon the successful capabilities demonstrated aboard the Curiosity Rover during NASA's current Mars Mission. Yellowjacket is the first rock targeted by

  11. Jackson Square | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jackson Square Jackson Square Construction of Jackson Square Shopping Center.

  12. New Online Tool Creates One-Stop Shop for Federal Program Opportunities That Support Tribal Energy Development

    Broader source: Energy.gov [DOE]

    The White House Council on Native American Affairs Energy Subgroup launched a new online tool that provides a centralized repository of federal funding and technical assistance programs that can support energy project development for Tribes and Alaska Native villages and corporations.

  13. Development of a locomotive engine condition monitoring system

    SciTech Connect (OSTI)

    Broughton, C.; Holloway, R.; Webster, G.

    1997-12-31

    Outlines test procedures and results of a study of the application of the instantaneous crankshaft angular velocity (ICAV) engine condition monitoring system applied to three freight locomotives. The study involved the assessment of a prototype repair-shop diagnostic tool, based on prior experimental programs and the ICAV technology. Engine testing was carried out at four-month intervals for three separate trials on the locomotives. Experimental data obtained included power output, fuel consumption, cylinder firing pressure waveforms, and the ICAV waveforms. The performance of the ICAV system was judged on its ability to accurately predict the change in indicated mean effective pressure of each cylinder from one test to the next.

  14. Measure Guideline. Wood Window Repair, Rehabilitation, and Replacement

    SciTech Connect (OSTI)

    Baker, P.; Eng, P.

    2012-12-01

    This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

  15. Simple Maintenance Saves Costly Furnace Repair/Replacement | Department of

    Energy Savers [EERE]

    Simon Edelman About Us Simon Edelman - Chief Creative Officer Simon Edelman Simon Edelman is Chief Creative Officer for the U.S. Department of Energy. He works with the digital content team to to develop, create, and expand visual content that tells the story of the Energy Department, its employees, and the work they do. Prior to joining the Energy.gov team, Simon founded a creative agency in Chicago, worked as Creative Director for Illinois Governor Pat Quinn, and was a producer, writer, and

  16. Microsoft Word - LL-LOW erosion repair.doc

    Broader source: Energy.gov (indexed) [DOE]

    Average annual precipitation ranges between 20 and 25 inches, and much of it is from snow that falls in late winter or early spring. An area approximately 5 acres in size...

  17. Repair welding of fusion reactor components. Second year technical report

    SciTech Connect (OSTI)

    Chin, B.A.

    1993-05-15

    Experiments have shown that irradiated Type 316 stainless steel is susceptible to heat-affected-zone (HAZ) cracking upon cooling when welded using the gas tungsten arc (GTA) process under lateral constraint. The cracking has been hypothesized to be caused by stress-assisted helium bubble growth and rupture at grain boundaries. This study utilized an experimental welding setup which enabled different compressive stresses to be applied to the plates during welding. Autogenous GTA welds were produced in Type 316 stainless steel doped with 256 appm helium. The application of a compressive stress, 55 MPa, during welding suppressed the previously observed catastrophic cracking. Detailed examinations conducted after welding showed a dramatic change in helium bubble morphology. Grain boundary bubble growth along directions parallel to the weld was suppressed. Results suggest that stress-modified welding techniques may be used to suppress or eliminate helium-induced cracking during joining of irradiated materials.

  18. SNL Researchers Assess Wind Turbine Blade Inspection and Repair Methods

    Broader source: Energy.gov [DOE]

    Flaws in wind turbine blades emanating from the manufacturing process are an important factor in blade reliability. To reduce uncertainty in the blade manufacturing process and improve their design and performance, SNL is working with industry to evaluate nondestructive inspection (NDI) technologies.

  19. Inspect and Repair Steam Traps, Energy Tips: STEAM, Steam Tip...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... There are four basic ways to test steam traps: temperature, sound, visual, and electronic. Recommended Steam Trap Testing Intervals * High-Pressure (150 psig and above): Weekly to ...

  20. Protein Bridges DNA Base and Nucleotide Excision Repair Pathways

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protective Forces NNSA has some of the best trained and best equipped forces protecting its nuclear weapons and material. Since the events of September 11, 2001, NNSA has hired additional armed security police officers. It has also shifted towards a paramilitary, "tactical response force" that utilizes a robust mix of offensive and defensive qualified officers who are well-trained in small team and weapons tactics. It has improved its training capabilities by expanding training ranges

  1. Mechanism of DNA interstrand cross-link processing by repair...

    Office of Scientific and Technical Information (OSTI)

    Authors: Wang, Renjing ; Persky, Nicole S. ; Yoo, Barney ; Ouerfelli, Ouathek ; Smogorzewska, Agata ; Elledge, Stephen J. ; Pavletich, Nikola P. 1 ; MSKCC) 2 ; Rockefeller) 2 ...

  2. Pressure Systems Program changes for those who operate, repair...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    This revised program along with the closely associated and recently revised "Welding and Brazing Supplement", will be launched starting November 9, 2015 by making the new...

  3. Crystal Structures of the Human DNA Repair Protein AGT Bound...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    N. Torrey Pines Rd., La Jolla, California 92037, USA. 2 Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania...

  4. Multi-Channel Auto-Dilution System for Remote Continuous Monitoring of High Soil-CO2 Fluxes

    SciTech Connect (OSTI)

    Amonette, James E.; Barr, Jonathan L.

    2009-04-23

    Geological sequestration has the potential capacity and longevity to significantly decrease the amount of anthropogenic CO2 introduced into the atmosphere by combustion of fossil fuels such as coal. Effective sequestration, however, requires the ability to verify the integrity of the reservoir and ensure that potential leakage rates are kept to a minimum. Moreover, understanding the pathways by which CO2 migrates to the surface is critical to assessing the risks and developing remediation approaches. Field experiments, such as those conducted at the Zero Emissions Research and Technology (ZERT) project test site in Bozeman, Montana, require a flexible CO2 monitoring system that can accurately and continuously measure soil-surface CO2 fluxes for multiple sampling points at concentrations ranging from background levels to several tens of percent. To meet this need, PNNL is developing a multi-port battery-operated system capable of both spatial and temporal monitoring of CO2 at concentrations from ambient to at least 150,000 ppmv. This report describes the system components (sampling chambers, measurement and control system, and power supply) and the results of a field test at the ZERT site during the late summer and fall of 2008. While the system performed well overall during the field test, several improvements to the system are suggested for implementation in FY2009.

  5. Mars Rover's ChemCam Instrument gets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Rover's ChemCam Instrument gets sharper vision May 21, 2015 Novel software update fixes autofocus glitch LOS ALAMOS, N.M., May 21, 2015-NASA's Mars Curiosity Rover's "ChemCam" instrument just got a major capability fix, as Los Alamos National Laboratory scientists uploaded a software repair for the auto-focus system on the instrument. "Last November we discovered that a small laser used to focus the ChemCam telescope on its targets had failed" said Roger Wiens, instrument

  6. PowerPoint Presentation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    * Machine shop * LH lab * Power systems and computer shop * Diagnostics setup lab * Welding shop 5 Year 513-514 2003 Some C-Mod Specific Instrumentation * 360 TF joint...

  7. Byers Auto Group: A Case Study Into The Economics, Zoning, and Overall Process of Installing Small Wind Turbines at Two Automotive Dealerships in Ohio (Presentation)

    SciTech Connect (OSTI)

    Sinclair, K.; Oteri, F.

    2011-05-01

    This presentation provides the talking points about a case study on the installation of a $600,000 small wind project, the installation process, estimated annual energy production and percentage of energy needs met by the turbines.

  8. Byers Auto Group: A Case Study Into The Economics, Zoning, and Overall Process of Installing Small Wind Turbines at Two Automotive Dealerships in Ohio

    SciTech Connect (OSTI)

    Oteri, F.; Sinclair, K.

    2011-11-01

    This paper provides the talking points about a case study on the installation of a $600,000 small wind project, the installation process, estimated annual energy production and percentage of energy needs met by the turbines.

  9. Single taphole blast furnace casthouse performance optimizing cost and availability

    SciTech Connect (OSTI)

    Fowles, R.D.; Searls, J.B.; Peay, W.R.; Brenneman, R.G.

    1995-12-01

    The No. 2 blast furnace is a single taphole furnace with a convection air-cooled iron trough. The iron runner system is designed to fill four 90 ton open-top ladles per cast, which are transported by locomotive to the steel shop. The slag runner system is capable of filling three 800 ft{sup 3} slag pots per cast. The No. 2 blast furnace was blown in from mini-reline with this new casthouse configuration in early December 1991. It was operated for nearly three years until it was banked for planned stove repairs and a trough rebuild in late September 1994. During this period, the furnace produced just over 2.5 million tons of hot metal across the original trough refractory lining system, with 13 intermediate hot patch castable repairs. The entire casthouse refractory usage (main trough, runner systems, and covers) during this campaign was 1.06 pounds per net ton of hot metal. Investigation of the lining during demolition indicated that the trough lining campaign could have been extended to at least 3.0 million tons. This paper will discuss how operating practices, mechanical design, refractory design, maintenance philosophy, and attention to detail synergistically contributed to the long campaign life and low refractory consumption rate.

  10. VALIDATION OF SPRING OPERATED PRESSURE RELIEF VALVE TIME TO FAILURE AND THE IMPORTANCE OF STATISTICALLY SUPPORTED MAINTENANCE INTERVALS

    SciTech Connect (OSTI)

    Gross, R; Stephen Harris, S

    2009-02-18

    The Savannah River Site operates a Relief Valve Repair Shop certified by the National Board of Pressure Vessel Inspectors to NB-23, The National Board Inspection Code. Local maintenance forces perform inspection, testing, and repair of approximately 1200 spring-operated relief valves (SORV) each year as the valves are cycled in from the field. The Site now has over 7000 certified test records in the Computerized Maintenance Management System (CMMS); a summary of that data is presented in this paper. In previous papers, several statistical techniques were used to investigate failure on demand and failure rates including a quantal response method for predicting the failure probability as a function of time in service. The non-conservative failure mode for SORV is commonly termed 'stuck shut'; industry defined as the valve opening at greater than or equal to 1.5 times the cold set pressure. Actual time to failure is typically not known, only that failure occurred some time since the last proof test (censored data). This paper attempts to validate the assumptions underlying the statistical lifetime prediction results using Monte Carlo simulation. It employs an aging model for lift pressure as a function of set pressure, valve manufacturer, and a time-related aging effect. This paper attempts to answer two questions: (1) what is the predicted failure rate over the chosen maintenance/ inspection interval; and do we understand aging sufficient enough to estimate risk when basing proof test intervals on proof test results?

  11. Structural basis for recognition of 5'-phosphotyrosine adducts by TDP2

    SciTech Connect (OSTI)

    Shi, Ke; Kurahash, Kayo; Gao, Rui; Tsutakawa, Susan E.; Tainer, John A.; Pommier, Yves; Aihara, Hideki

    2012-12-19

    The DNA repair enzyme TDP2 resolves 5'-phosphotyrosyl-DNA adducts, and is responsible for resistance to anti-cancer drugs that target covalent topoisomerase-DNA complexes. TDP2 also participates in key signaling pathways during development and tumorigenesis, and cleaves a protein-RNA linkage during picornavirus replication. The crystal structure of zebrafish TDP2 bound to DNA reveals a deep and narrow basic groove that selectively accommodates the 5'-end of single-stranded DNA in a stretched conformation. The crystal structure of the full-length C. elegans TDP2 shows that this groove can also accommodate an acidic peptide stretch in vitro, with Glu and Asp sidechains occupying the DNA backbone phosphate binding sites. This extensive molecular mimicry suggests a potential mechanism for auto-regulation and how TDP2 may interact with phosphorylated proteins in signaling. Our study provides a framework to interrogate functions of TDP2 and develop inhibitors for chemotherapeutic and antiviral applications.

  12. All | OpenEI Community

    Open Energy Info (EERE)

    auto Type Term Title Author Replies Last Post sort icon Blog entry auto Historic Fuel Standards Graham7781 30 Aug 2012 - 15:1...

  13. Department of Energy to Invest Up To $30 Million to Accelerate...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    visiting the North American International Auto Show in Detroit today. "Coming on the ... This alliance will perform pre-competitive research and engage auto suppliers to advance ...

  14. Autonomie Modeling Tool Improves Vehicle Design and Testing,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with EERE support, is helping U.S. auto manufacturers develop the next generation ... with EERE support, is helping U.S. auto manufacturers develop the next generation ...

  15. Microsoft Word - Sandalow Detroit National Summit Speech 6-17...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    As Ed Montgomery, President Obama's Director for Recovery of Auto Communities and Workers, has said, "behind the 'facts and figures' of the economic downturn and the auto crisis ...

  16. Washington: State Ferries Run Cleaner With Biodiesel | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Addthis Related Articles Auto and passenger ferries operated by the Washington State ... SEP Success Story: Washington State Becomes Largest Public Consumer of Biodiesel Auto and ...

  17. Energy Media Advisories | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 21, 2015 Thursday: Secretary Moniz to Make Remarks at the Washington Auto Show Tomorrow, Energy Secretary Ernest Moniz will attend the Washington Auto Show and make an...

  18. Underwater inspection, maintenance and repair study for the 40 MW OTEC pilot plant

    SciTech Connect (OSTI)

    Fishel, K.; Aboumrad, J.; Clinkenbeard, J.; Spiro, J.

    1982-06-01

    The objective of this research was to study candidate OTEC 40 MWe systems to determine underwater inspection requirements, and the instrumentation, equipment and data acquisition systems which will be required for inspection of the structure and monitoring of the operational condition of the system. The study was based on current literature, existing offshore platforms, discussions with experts in the field, and on the experience and judgment of the investigators. Results of the study are published in the form of a report showing the background, approach, data and information obtained. Conclusions and recommendations are presented.

  19. Research Recruiting Endogenous Tissue Stem Cells to Repair Injury and Degeneration

    SciTech Connect (OSTI)

    Peterson, Daniel A.

    2014-10-22

    This report lists bibliographic information about meeting papers and journal articles resulting from this work, and basic information on new grant applications that this work was used to support.

  20. Recent developments with the human repair genes ERCC2, ERCC4, and XRCC1

    SciTech Connect (OSTI)

    Thompson, L.H.; Caldecott, K.W.; Brookman, K.W.; Weber, C.A.; Salazar, E.S.; Takayama, K.; Fornace, A.J.

    1992-11-06

    ERCC2 was first identified as a gene on human chromosome 19 that complemented the UV sensitivity of CHO UV5 cells in somatic cell hybrids. Subsequent studies localized ERCC2 to the same chromosomal region (19q13.2--13.3) as the ERCC1 gene and showed that the two genes were less than 250 kb apart. Cloning of ERCC2 was accomplished by transfection of genomic DNA into UV5 cells and rescue of the gene from a secondary transformant. Recovery of the gene was aided by the presence of repetitive sequences that were detected on Southern blots with a probe for Alu-family repeats. ERCC2, which is 19 kb in size, quantitatively corrected the UV sensitivity and incision defect in UV5 cells upon transfection. An ERCC2 CDNA clone was recovered from the pcD2 expression library. Although this clone was truncated at the 5 in. end, it conferred transient, but not stable, correction to UV5 cells upon transfection. Based on genomic sequence, this clone was extended by oligonucleotide addition to obtain minigene constructs in which the complete open reading frame (ORF) was present. Translation of the ERCC2 ORF gives an amino acid sequence that has 72% similarity with the S. cerevisiae RAD3 protein, which encodes a DNA helicase.

  1. Vehicle Technologies Office Merit Review 2014: Active, Tailorable Adhesives for Dissimilar Material Bonding, Repair and Assembly

    Broader source: Energy.gov [DOE]

    Presentation given by Michigan State University at 2014 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Office Annual Merit Review and Peer Evaluation Meeting about Active, tailorable...

  2. Vehicle Technologies Office Merit Review 2015: Active, Tailorable Adhesives for Dissimilar Material Bonding, Repair and Assembly

    Broader source: Energy.gov [DOE]

    Presentation given by Michigan State University at 2015 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Office Annual Merit Review and Peer Evaluation Meeting about active, tailorable...

  3. Laser Microperforated Biodegradable Microbial Polyhydroxyalkanoate Substrates for Tissue Repair Strategies: An Infrared Microspectroscopy Studey

    SciTech Connect (OSTI)

    G Ellis; P Cano; M Jadraque; M Martin; L Lopez; T Nunez; E de la Pena; C Marco; L Garrido

    2011-12-31

    Flexible and biodegradable film substrates prepared by solvent casting from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV) solutions in chloroform were microperforated by ultraviolet laser ablation and subsequently characterized using infrared (IR) microspectroscopy and imaging techniques and scanning electron microscopy (SEM). Both transmission synchrotron IR microspectroscopy and attenuated total reflectance microspectroscopy measurements demonstrate variations in the polymer at the ablated pore rims, including evidence for changes in chemical structure and crystallinity. SEM results on microperforated PHBHV substrates after cell culture demonstrated that the physical and chemical changes observed in the biomaterial did not hinder cell migration through the pores.

  4. Damage tolerance assessment of bonded composite doubler repairs for commercial aircraft applications

    SciTech Connect (OSTI)

    Roach, D.

    1998-08-01

    The Federal Aviation Administration has sponsored a project at its Airworthiness Assurance NDI Validation Center (AANC) to validate the use of bonded composite doublers on commercial aircraft. A specific application was chosen in order to provide a proof-of-concept driving force behind this test and analysis project. However, the data stemming from this study serves as a comprehensive evaluation of bonded composite doublers for general use. The associated documentation package provides guidance regarding the design, analysis, installation, damage tolerance, and nondestructive inspection of these doublers. This report describes a series of fatigue and strength tests which were conducted to study the damage tolerance of Boron-Epoxy composite doublers. Tension-tension fatigue and ultimate strength tests attempted to grow engineered flaws in coupons with composite doublers bonded to aluminum skin. An array of design parameters, including various flaw scenarios, the effects of surface impact, and other off-design conditions, were studied. The structural tests were used to: (1) assess the potential for interply delaminations and disbonds between the aluminum and the laminate, and (2) determine the load transfer and crack mitigation capabilities of composite doublers in the presence of severe defects. A series of specimens were subjected to ultimate tension tests in order to determine strength values and failure modes. It was demonstrated that even in the presence of extensive damage in the original structure (cracks, material loss) and in spite of non-optimum installations (adhesive disbonds), the composite doubler allowed the structure to survive more than 144,000 cycles of fatigue loading. Installation flaws in the composite laminate did not propagate over 216,000 fatigue cycles. Furthermore, the added impediments of impact--severe enough to deform the parent aluminum skin--and hot-wet exposure did not effect the doubler`s performance. Since the tests were conducting using extreme combinations of flaw scenarios (sizes and collocation) and excessive fatigue load spectrums, the performance parameters were arrived at in a conservative manner.

  5. Grinding assembly, grinding apparatus, weld joint defect repair system, and methods

    DOE Patents [OSTI]

    Larsen, Eric D.; Watkins, Arthur D.; Bitsoi, Rodney J.; Pace, David P.

    2005-09-27

    A grinding assembly for grinding a weld joint of a workpiece includes a grinder apparatus, a grinder apparatus includes a grinding wheel configured to grind the weld joint, a member configured to receive the grinding wheel, the member being configured to be removably attached to the grinder apparatus, and a sensor assembly configured to detect a contact between the grinding wheel and the workpiece. The grinding assembly also includes a processing circuitry in communication with the grinder apparatus and configured to control operations of the grinder apparatus, the processing circuitry configured to receive weld defect information of the weld joint from an inspection assembly to create a contour grinding profile to grind the weld joint in a predetermined shape based on the received weld defect information, and a manipulator having an end configured to carry the grinder apparatus, the manipulator further configured to operate in multiple dimensions.

  6. Turbine superalloy component defect repair with low-temperature curing resin

    DOE Patents [OSTI]

    Hunt, David W.; Allen, David B.

    2015-09-08

    Voids, cracks or other similar defects in substrates of thermal barrier coated superalloy components, such as turbine blades or vanes, are filled with resin, without need to remove substrate material surrounding the void by grinding or other processes. The resin is cured at a temperature under 200.degree. C., eliminating the need for post void-filling heat treatment. The void-filled substrate and resin are then coated with a thermal barrier coating.

  7. [Repair of a cable as it relates to the North Pacific Acoustic Laboratory

    SciTech Connect (OSTI)

    Spindel, R.C.; Worcester, P.F.

    1998-12-31

    The ultimate limits of long-range sonar are imposed by ocean variability and the ambient sound field. Scattering from internal waves limits the temporal and spatial coherence of the received signal. Low frequency noise is dominated by shipping and ultimately, by wave-breaking processes. The resulting granularity of the noise field can be exploited for detection and localization purposes. The ultimate objective is to understand the fundamental limits to signal processing imposed by these ocean processes, to enable advanced signal processing techniques, including matched field processing and other adaptive array processing methods, to capitalize on the three-dimensional character of the sound and noise fields. The objective of this research is to understand the basic physics of low frequency, broadband propagation and the effects of environmental variability on signal stability and coherence. In particular, it focuses on 3-D wave front coherence (horizontal, vertical, and temporal), on the details of signal energy redistribution through mode scattering, on signal and noise variability on ocean-basin scales, and on environmental processes such as internal waves that most affect long-range coherence.

  8. Museum Hours

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    provide a listening-assistance system and translations of the script in French and Spanish. Sorry, a local shop has closed The Otowi Bookstore and Museum Shop, which had been...

  9. PUBLISHED QUARTBRLY BY THE UNIVERSITY OF NEVADA

    National Nuclear Security Administration (NNSA)

    ... An iron-stained sandstone(?) mined here by Frank Smith of Palmdale, California, is used as ... A large sheet iron building serves as hoist house, black- smith shop, and general shop. ...

  10. 5

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    7.0 - SHOP CRANES April 25, 2016 Rev 1 Page 1 CHAPTER 7.0 TABLE OF CONTENTS 7.0 SHOP CRANES ................................................................................................................................... 3 7.1 SCOPE .............................................................................................................................................. 3 7.2 GENERAL REQUIREMENTS

  11. Lumens Placard (Green) | Department of Energy

    Energy Savers [EERE]

    Green) Lumens Placard (Green) PDF icon Lumens: The new way to shop for light More Documents & Publications Lumens Placard (Black...

  12. Reduce Waste and Save Energy this Holiday Season

    Broader source: Energy.gov [DOE]

    Reduce waste and save energy this holiday season whether you're shopping, eating, partying, decorating, or wrapping.

  13. Sandia National Laboratories: Products and Services

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Gages, Fixtures, Molds Power Sources & Batteries Manufacturing, Shop Overflow through the Manufacturing Processes & Services Department Energy, Security & International Procurement...

  14. Comparing Appliance and Lighting Energy Costs Online Just Got Easier

    Broader source: Energy.gov [DOE]

    The new Energy Labeling Rule makes it easy to compare energy use and costs when shopping for appliances or lighting.

  15. Front Burner- Issue 15

    Broader source: Energy.gov [DOE]

    The Cybersecurity Front Burner Issue No. 15 addresses the DOE eSCRM Program and Secure Online Shopping.

  16. Reuse of secondhand TVs exported from Japan to the Philippines

    SciTech Connect (OSTI)

    Yoshida, Aya; Terazono, Atsushi

    2010-06-15

    The trade of secondhand electrical and electronic equipment (EEE) from developed to developing countries has become a growing environmental issue owing to concerns about improper recycling of these goods in developing countries. We followed a 12-m cargo container of cathode-ray-tube color TVs exported from Japan to the Philippines in February 2008. We surveyed the number of TVs damaged in transport, as well as the number of malfunctioning TVs from this shipment. In addition, we present the results of interviews with 113 Filipino consumers who intended to buy secondhand EEE at nine secondhand shops in Metro Manila. Approximately 3% of the imported TVs were damaged upon arrival. The importer sold some of the units directly to local dealers, and kept the rest to repair, refurbish and resell. Approximately 40% of the imported TVs malfunctioned and needed repair in addition to basic reconditioning. Most interviewees indicated that they prefer to buy secondhand EEE because the prices are lower than those of brand-new products. Consumers indicated that they planned on using the product for an average of about 5 years, but the actual period of use may be lower. Most end-of-life EEE in the Philippines is dismantled and recycled by unregulated companies and untrained individuals in markets or near landfill sites, and it is clear that a proper collection system and treatment methods are needed for e-waste. In addition to the material flow of secondhand TVs, we also discuss several economic aspects and appropriate control measures of the international reuse of secondhand TVs.

  17. Auto-calibrated scanning-angle prism-type total internal reflection microscopy for nanometer-precision axial position determination and optional variable-illumination-depth pseudo total internal reflection microscopy

    DOE Patents [OSTI]

    Fang, Ning; Sun, Wei

    2015-04-21

    A method, apparatus, and system for improved VA-TIRFM microscopy. The method comprises automatically controlled calibration of one or more laser sources by precise control of presentation of each laser relative a sample for small incremental changes of incident angle over a range of critical TIR angles. The calibration then allows precise scanning of the sample for any of those calibrated angles for higher and more accurate resolution, and better reconstruction of the scans for super resolution reconstruction of the sample. Optionally the system can be controlled for incident angles of the excitation laser at sub-critical angles for pseudo TIRFM. Optionally both above-critical angle and sub critical angle measurements can be accomplished with the same system.

  18. Nuclear localization of the DNA repair scaffold XRCC1: Uncovering the functional role of a bipartite NLS

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Kirby, Thomas W.; Gassman, Natalie R.; Smith, Cassandra E.; Pedersen, Lars C.; Gabel, Scott A.; Sobhany, Mack; Wilson, Samuel H.; London, Robert E.

    2015-08-25

    We have characterized the nuclear localization signal (NLS) of XRCC1 structurally using X-ray crystallography and functionally using fluorescence imaging. Crystallography and binding studies confirm the bipartite nature of the XRCC1 NLS interaction with Importin α (Impα) in which the major and minor binding motifs are separated by >20 residues, and resolve previous inconsistent determinations. Binding studies of peptides corresponding to the bipartite NLS, as well as its major and minor binding motifs, to both wild-type and mutated forms of Impα reveal pronounced cooperative binding behavior that is generated by the proximity effect of the tethered major and minor motifs ofmore » the NLS. The cooperativity stems from the increased local concentration of the second motif near its cognate binding site that is a consequence of the stepwise binding behavior of the bipartite NLS. We predict that the stepwise dissociation of the NLS from Impα facilitates unloading by providing a partially complexed intermediate that is available for competitive binding by Nup50 or the Importin β binding domain. This behavior gives a basis for meeting the intrinsically conflicting high affinity and high flux requirements of an efficient nuclear transport system.« less

  19. Nuclear localization of the DNA repair scaffold XRCC1: Uncovering the functional role of a bipartite NLS

    SciTech Connect (OSTI)

    Kirby, Thomas W.; Gassman, Natalie R.; Smith, Cassandra E.; Pedersen, Lars C.; Gabel, Scott A.; Sobhany, Mack; Wilson, Samuel H.; London, Robert E.

    2015-08-25

    We have characterized the nuclear localization signal (NLS) of XRCC1 structurally using X-ray crystallography and functionally using fluorescence imaging. Crystallography and binding studies confirm the bipartite nature of the XRCC1 NLS interaction with Importin α (Impα) in which the major and minor binding motifs are separated by >20 residues, and resolve previous inconsistent determinations. Binding studies of peptides corresponding to the bipartite NLS, as well as its major and minor binding motifs, to both wild-type and mutated forms of Impα reveal pronounced cooperative binding behavior that is generated by the proximity effect of the tethered major and minor motifs of the NLS. The cooperativity stems from the increased local concentration of the second motif near its cognate binding site that is a consequence of the stepwise binding behavior of the bipartite NLS. We predict that the stepwise dissociation of the NLS from Impα facilitates unloading by providing a partially complexed intermediate that is available for competitive binding by Nup50 or the Importin β binding domain. This behavior gives a basis for meeting the intrinsically conflicting high affinity and high flux requirements of an efficient nuclear transport system.

  20. Develop baseline computational model for proactive welding stress management to suppress helium induced cracking during weld repair

    Broader source: Energy.gov [DOE]

    There are over 100 nuclear power plants operating in the U.S., which generate approximately 20% of the nation’s electricity. These plants range from 15 to 40 years old. Extending the service lives...

  1. Meeting with Greg Horton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CAES Facility and Business Equipment Repair Information * Maintenance or repair of business equipment o For repair of copiers, fax machines, printer, etc., contact one of the CAES...

  2. Energy Department Offers $50 Million to Advance Fuel Efficient...

    Energy Savers [EERE]

    Offers 50 Million to Advance Fuel Efficient Autos Energy Department Offers 50 Million to Advance Fuel Efficient Autos January 29, 2014 - 12:00am Addthis The Energy Department on ...

  3. FEI Nova 200 Dual-Beam SEM/FIB

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    milling * GIS for Pt deposition * Kleindiek nanomanipulator for specimen lift-out * Oxford Inca EDS system * AutoTEM, AutoFIB, and slice and view automation software Fabricating...

  4. EERE Success Story-Washington: Putting More Solar on More Rooftops...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with a ribbon cutting at the Auto-Spa car wash. Mercer Island celebrates the 500th Solarize installation in the state of Washington with a ribbon cutting at the Auto-Spa car wash. ...

  5. Just Plain Cool, the 3D Printed Shelby Cobra | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Shelby Cobra celebrated its 50th anniversary at the Detroit Auto Show in early January. ... Bottom line the auto industry could save energy and time with additive manufacturing. The ...

  6. Washington: Putting More Solar on More Rooftops in Washington...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    with a ribbon cutting at the Auto-Spa car wash. Mercer Island celebrates the 500th Solarize installation in the state of Washington with a ribbon cutting at the Auto-Spa car wash. ...

  7. Lightweight Technology Resolved Challenge Facing the Chevy Spark...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    August 18, 2015 - 11:34am Addthis The Chevy Spark EV at the Washington Auto Show. The Chevy Spark EV at the Washington Auto Show. Technology innovation comes in many forms - ...

  8. Photo of the Week: Air Supply | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    This week, the latest vehicles technologies are on display at the Washington Auto Show in ... Photo of the Week: the 2014 Washington Auto Show In this August 2013 photo, Pete Johnson ...

  9. Fuel Cells News | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and the L.A. Auto Show David Friedman, Principal Deputy Assistant Secretary, Office of Energy Efficiency & Renewable Energy, visited the L.A. Auto Show in November 2015. ...

  10. ORISE: Media Analysis and Monitoring

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    such as AutoINFORM (Auto Immunization News FOR Managers), that enable the monitoring of social media, email and other Web content. On average, ORISE tracks, codes and analyzes...

  11. Secretary Moniz Announces Nearly $50 Million to Advance High...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Nearly 50 Million to Advance High-Tech, Fuel Efficient American Autos Secretary Moniz Announces Nearly 50 Million to Advance High-Tech, Fuel Efficient American Autos January 22, ...

  12. The Future is Now for Advanced Vehicles

    Broader source: Energy.gov [DOE]

    Go behind the scenes at the Washington Auto Show, where the next generation of advanced vehicles is here today.

  13. Secretary Moniz Announces Nearly $50 Million to Advance High-Tech, Fuel

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Efficient American Autos | Department of Energy Nearly $50 Million to Advance High-Tech, Fuel Efficient American Autos Secretary Moniz Announces Nearly $50 Million to Advance High-Tech, Fuel Efficient American Autos January 22, 2014 - 10:29am Addthis WASHINGTON - At the Washington Auto Show today U.S. Energy Secretary Ernest Moniz announced nearly $50 million to accelerate research and development of new vehicle technologies that give drivers and businesses more transportation options and

  14. A look back at Union Carbides FIRST 20 Years in Nuclear Energy...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    large-scale precision machining of beryllium began. "1953 - Additional uranium casting facilities and another uranium machining shop were installed and completed by fall. A...

  15. Tips: Appliances | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Shopping for Appliances Purchase the most energy-efficient appliances. Kitchen Appliances ... Home Office and Electronics Select energy-efficient electronics and use them efficiently. ...

  16. Coeur dAlene Tribe Energy Efficiency and Conservation Block...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Project Specific Buildings 34 Tribally Owned Buildings Northwest Region 10, Plummer, Idaho Benewah Medical Center (BMC) Tribal Housing Authority & Shop Tribal Police Headquarters ...

  17. bbergman | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    bbergman Ames Laboratory Profile Brian Bergman Facil Mechanic III Facilities Services Maintenance Shop Phone Number: 515-294-4346 Email Address: bbergman@ameslab.gov

  18. flanders | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    flanders Ames Laboratory Profile Duane Flanders Sheet Metal Mech Facilities Services Maintenance Shop Phone Number: 515-294-1746 Email Address: flanders@ameslab.gov

  19. gharper | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    gharper Ames Laboratory Profile Gregory Harper Sys Control Tech Facilities Services Maintenance Shop Phone Number: 515-294-1746 Email Address: gharper

  20. Lumens Placard (Black) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon Lumens: The new way to shop for light More Documents & Publications Lumens Placard (Green) Lighting Tip Card Lighting Tip Card

  1. Lumens Placard (Green) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon Lumens: The new way to shop for light More Documents & Publications Lumens Placard (Black) Lighting Tip Card Lighting Tip Card

  2. RadiaBeam PPT template

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Machine shops (clean and regular) Assembly area Magnetic measurements lab Optics lab Hot test cell (up to 9 MeV) Clean room Chemical processing RF test...

  3. RAPID/About/FAQ | Open Energy Information

    Open Energy Info (EERE)

    shop" for permitting and siting information for bulk transmission lines and renewable energy projects and includes information and resources such as permit applications,...

  4. OSTI, US Dept of Energy, Office of Scientific and Technical Informatio...

    Office of Scientific and Technical Information (OSTI)

    see if there's information I may not have realized I need yet. Related Topics: data, datasets, Digital Object Identifier, DOE Data Explorer (DDE), explore, search, window shopping

  5. OSTI, US Dept of Energy, Office of Scientific and Technical Informatio...

    Office of Scientific and Technical Information (OSTI)

    information I may not have realized I need yet. Related Topics: data, datasets, Digital Object Identifier, DOE Data Explorer (DDE), explore, search, window shopping Read more... ...

  6. NHC Large Flume | Open Energy Information

    Open Energy Info (EERE)

    V to 480 V, 3 phase On-Site fabrication capabilityequipment Full on-site carpentry, machine, and instrumentation shop Special Characteristics Hydro | Hydrodynamic Testing...

  7. Stennis Flume | Open Energy Information

    Open Energy Info (EERE)

    440220110 electric available On-Site fabrication capabilityequipment Small machine shop Special Characteristics Special Characteristics Yes Types of Co-located...

  8. Statistics Show Bearing Problems Cause the Majority of Wind Turbine...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    data-sharing partners, including wind turbine and wind turbine gearbox manufacturers and ownersoperators, gearbox rebuild shops, and operation and maintenance service providers. ...

  9. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ; Crawford, Clark ProteinShop is a graphical environment that facilitates a solution to the protein prediction problem through a combination of unique features and capabilities. ...

  10. DOE16-002-MiniReport-ATVM-v08

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Eclipse Automation, Inc., a Canadian supplier of custom automated manufacturing equipment, opened engineering o ces and a service shop in Fremont, citing Tesla as a driving factor ...

  11. RESEARCH PERSONNEL AND ENGINEERING STAFF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research Scientist (20%) Engineering Staff Walter Chapman, Mech. Engineer - To 93002 Greg Derrig, Senior Mechanical Engineer Lee Norris, Instr. Shop Supervisor - From 10102 ...

  12. Leavenworth Tree Lighting

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Join HERO for our annual Leavenworth Tree Lighting Ceremony & Shopping SATURDAY DECEMBER 12, 2015 Leavenworth Christmas Lighting Festival Visitors return year after year for some...

  13. EPA and DOE Release Annual Fuel Economy Guide with 2014 Models...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the financial and environmental bottom line are high priorities when shopping for a ... greenhouse gas rating for each model, providing a quick and easy way for ...

  14. Jefferson Lab recognizes its Outstanding Small Business Contractor...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sharon Harrah (center), owner of Triad Machine Shop located in Newport News, Va., receives the award plaque from JLab Director Christoph Leemann (right). Harrah is accompanied by...

  15. Crivelli, Silvia; Kreylos, Oliver; Max, Nelson; Hamann, Bernd...

    Office of Scientific and Technical Information (OSTI)

    and steer a protein structure prediction process that may be running on a remote machine. ProteinShop was used to create initial configurations for a protein structure...

  16. Tips: Appliances | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    Appliances account for about 13% of your household's energy costs, with refrigeration, cooking, and laundry at the top of the list. Learn about: Shopping for Appliances Purchase ...

  17. Steep Gradient Flume | Open Energy Information

    Open Energy Info (EERE)

    instrumentation and electronics shop Past Pertinent Test Experience Mountain stream sediment transport, RFID tagged materials for sediment transport particle tracking Special...

  18. Intranet | APS X-ray Science Division

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IT Helpdesk Stockroom Catalog | Shopping Cart | Stockroom (Bldg. 401) 2-9082 Key Request Phone Request Argonne Internal Resources: 401 Grill Inside Argonne AMOS, GatePass,...

  19. mdotzler | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    mdotzler Ames Laboratory Profile Mike Dotzler Facil Mechanic III Facilities Services Maintenance Shop Phone Number: 515-294-4346 Email Address: mdotzler

  20. rberrett | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rberrett Ames Laboratory Profile Ronald Berrett Sys Control Tech Facilities Services Maintenance Shop Phone Number: 515-294-1746 Email Address: rberrett

  1. rmalmq | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rmalmq Ames Laboratory Profile Richard Malmquist Facil Mechanic III Facilities Services Maintenance Shop Phone Number: 515-294-1228 Email Address: rmalmq

  2. BPA-2010-02071-FOIA Correspondence

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    rebuilding of lines and visualizations (Photo-shopped renderins) Mr. Mark Korsness. Civil Engineer. Transmission Project Manager. has been designated as the Authorizing...

  3. vdahl | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    vdahl Ames Laboratory Profile Vincent Dahl Mgr Facilities Mnt Facilities Services Maintenance Shop Phone Number: 515-294-1746 Email Address: vdahl...

  4. ALSNews Vol. 320

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Staff Machine Shop Operations Update News Links ringleaders Ring Leaders Shutdown this Summer ALS Project Manager Steve Rossi prepares users for the upcoming ALS shutdown. Want...

  5. CX-004126: Categorical Exclusion Determination

    Office of Energy Efficiency and Renewable Energy (EERE)

    Machine Shop Equipment BurnCX(s) Applied: B1.12Date: 08/02/2010Location(s): New MexicoOffice(s): Sandia Site Office

  6. Environment/Health/Safety (EHS)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Safety Minute Brief Introduction At Home Authorizations Laboratory Area Office Area Shop Area Reporting Ergonomics (general) Training Supervisor Responsibilities Site- Wide...

  7. Small Wind Guidebook/First, How Can I Make My Home More Energy...

    Open Energy Info (EERE)

    by 25% to 50%. Replacing 15 incandescent light bulbs with energy efficient bulbs can save approximately 50 per year. When shopping for appliances, look for the Energy Star...

  8. Conte Small Flume | Open Energy Information

    Open Energy Info (EERE)

    carpentry shop with welding and machining capabilities Past Pertinent Test Experience Fish passage structures, screening, bridge pier scour, mixing pump Special Characteristics...

  9. Conte Large Flume | Open Energy Information

    Open Energy Info (EERE)

    carpentry shop with welding and machining capabilities Past Pertinent Test Experience Fish passage structures, screening, bridge pier scour, mixing pump Special Characteristics...

  10. Solfex Limited | Open Energy Information

    Open Energy Info (EERE)

    Jump to: navigation, search Name: Solfex Limited Address: Energy Arena Bannister Hall Works Off Shop Lane, Higher Walton Preston, Lancashire PR5 4DZ Place: Preston, United...

  11. Goodbye, Watts. Hello, Lumens. (High-Resolution EPS Billboard)

    Broader source: Energy.gov [DOE]

    High-resolution EPS of billboard reading, 'Goodbye Watts. Hello Lumens. The new way to shop for light. Energysaver.gov

  12. Goodbye, Watts. Hello, Lumens. (High-Resolution JPG Billboard)

    Broader source: Energy.gov [DOE]

    High-resolution JPG of billboard reading, 'Goodbye Watts. Hello Lumens. The new way to shop for light. Energysaver.gov

  13. Goodbye, Watts. Hello, Lumens. (Low-Resolution Billboard)

    Broader source: Energy.gov [DOE]

    Low-resolution JPG of billboard reading, 'Goodbye Watts. Hello Lumens. The new way to shop for light. Energysaver.gov

  14. Mission Support Alliance, LLC / Hanford Mission Support Contract...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    which emphasize creative solutions through ... That process requires an onsite assessment by HSS within 2 ... shops to limit worker exposure to exhaust by-products. ...

  15. Energy Performance Ratings for Windows, Doors, and Skylights...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Performance Ratings for Windows, Doors, and Skylights Energy Performance Ratings for Windows, Doors, and Skylights Before you shop for energy-efficient windows, doors, and ...

  16. Space Institute Tunnel | Open Energy Information

    Open Energy Info (EERE)

    Yes Available Sensors Flow, Strain, Turbulence Data Generation Capability Real-Time No Test Services Test Services Yes On-Site fabrication capabilityequipment Machine shop and...

  17. Workplace Charging: Tips to Install Charging Stations at your Leased Property

    Broader source: Energy.gov [DOE]

    Tenants consider many options when shopping for space that can meet their organizations’ needs, including sustainability, transportation, and technology requirements. Although they do not own the...

  18. Flying Cars | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research: Holiday Shopping & Electric Vehicles IMG0475 Innovation 247: We're Always Open primusenginefeaturedimage3 GE Innovation and Manufacturing in Europe ...

  19. Intelligent Rail Networks | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research: Holiday Shopping & Electric Vehicles IMG0475 Innovation 247: We're Always Open primusenginefeaturedimage3 GE Innovation and Manufacturing in Europe ...

  20. Collaborative Military Vehicle Design | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research: Holiday Shopping & Electric Vehicles IMG0475 Innovation 247: We're Always Open primusenginefeaturedimage3 GE Innovation and Manufacturing in Europe ...