Sample records for auto repair shop

  1. Incremental temporal reasoning in job shop scheduling repair

    E-Print Network [OSTI]

    Huang, Y.

    A working predictive schedule can be useless because of the various external or internal disruptions in a job shop. Total rescheduling may cause problems such as shop floor nervousness. Thus, the job shop scheduling repair ...

  2. Automotive Repair Shops Case Study ME 4171 Automotive Repair Shops

    E-Print Network [OSTI]

    include toxic and ignitable thinners, toxic paint wastes, paint sludges and oil- and solventcontaminated, these shops produce hazardous waste streams which include waste oils, oil filters, engine/hydraulic fluids can straighten bent frames, align hoods and fenders, and adjust panels. Oil is essential to the proper

  3. Exposure Evaluation for Benzene, Lead and Noise in Vehicle and Equipment Repair Shops

    SciTech Connect (OSTI)

    Sweeney, Lynn C.

    2013-04-10T23:59:59.000Z

    An exposure assessment was performed at the equipment and vehicle maintenance repair shops operating at the U. S. Department of Energy Hanford site, in Richland, Washington. The maintenance shops repair and maintain vehicles and equipment used in support of the Hanford cleanup mission. There are three general mechanic shops and one auto body repair shop. The mechanics work on heavy equipment used in construction, cranes, commercial motor vehicles, passenger-type vehicles in addition to air compressors, generators, and farm equipment. Services include part fabrication, installation of equipment, repair and maintenance work in the engine compartment, and tire and brake services. Work performed at the auto body shop includes painting and surface preparation which involves applying body filler and sanding. 8-hour time-weighted-average samples were collected for benzene and noise exposure and task-based samples were collected for lead dust work activities involving painted metal surfaces. Benzene samples were obtained using 3M™ 3520 sampling badges and were analyzed for additional volatile organic compounds. These compounds were selected based on material safety data sheet information for the aerosol products used by the mechanics for each day of sampling. The compounds included acetone, ethyl ether, toluene, xylene, VM&P naphtha, methyl ethyl ketone, and trichloroethylene. Laboratory data for benzene, VM&P naphtha, methyl ethyl ketone and trichloroethylene were all below the reporting detection limit. Airborne concentrations for acetone, ethyl ether, toluene and xylene were all less than 10% of their occupational exposure limit. The task-based samples obtained for lead dusts were submitted for a metal scan analysis to identify other metals that might be present. Laboratory results for lead dusts were all below the reporting detection limit and airborne concentration for the other metals observed in the samples were less than 10% of the occupational exposure limit. Noise dosimetry sampling was performed on a random basis and was representative of the different work activities within the four shops. Twenty three percent of the noise samples exceeded the occupational exposure limit of 85 decibels for an 8-hour time-weightedaverage. Work activities where noise levels were higher included use of impact wrenches and grinding wheels.

  4. automobile repair shops: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Millikelvin Lab OP105-112 Machine Shop OP132 Resistive Magnet Shop CICC Winding Area Transformers winding area and most of our resistive magnets, including the "45 T Hybrid"...

  5. The urban coffee shop

    E-Print Network [OSTI]

    Chadios, Konstantinos

    2005-01-01T23:59:59.000Z

    This thesis is an investigation of the role of the coffee shop in the urban environment throughout history. Coffee shops spread from the Arab world to Europe and then to the U.S. at the end of the seventeenth century. ...

  6. Quality electric motor repair: A guidebook for electric utilities

    SciTech Connect (OSTI)

    Schueler, V.; Douglass, J.

    1995-08-01T23:59:59.000Z

    This guidebook provides utilities with a resource for better understanding and developing their roles in relation to electric motor repair shops and the industrial and commercial utility customers that use them. The guidebook includes information and tools that utilities can use to raise the quality of electric motor repair practices in their service territories.

  7. CLAIMANT AUTO ACCIDENT REPORT For Completion by Driver

    E-Print Network [OSTI]

    Tullos, Desiree

    CLAIMANT AUTO ACCIDENT REPORT For Completion by Driver D E P A R T M E N T O F A D M I N I S T R Address City State Zip For what purpose was car being used at time of accident? Has damage been repaired signals did you give? Other Driver? Who investigated? Who Cited and Why? Describe Accident CONTINUE

  8. Job-Shop Scheduling in a Body Shop

    E-Print Network [OSTI]

    2012-10-20T23:59:59.000Z

    ing in a car body production line, where possible colli- sions between industrial robots have to be taken into ac- count. BSSP corresponds to a job-shop problem

  9. Software Engineer RockAuto www.RockAuto.com

    E-Print Network [OSTI]

    Liblit, Ben

    Software Engineer ­ RockAuto www.RockAuto.com Position Description Software is the foundation · Familiarity with open-source development technologies like PHP, Perl, JavaScript and C (Linux system Lane, Madison, WI 53719) Why RockAuto? Strategic and tactical impact. We're an e-commerce company

  10. University of California at Berkeley Shop Safety Policy Biomolecular Nanotechnology Center Machine Shop

    E-Print Network [OSTI]

    Healy, Kevin Edward

    by the manufacturer and within the equipment's Nationally Recognized Testing Laboratory (NRTL) listing. · All shop

  11. LOM_Shop_Monthly_Inspection_Record.xls

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Satisfactory R Requires follow-up U Urgent attention required Outside postings: Eye protection required; Authorized users only; User Shop Access List, Lead postings Inside...

  12. AutoSaved SDDS Plots

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AutoSaved SDDS Plots for Storage Ring Systems L4 and L5 Power and Vacuum Plots These plots are updated every 10 minutes L4 Beamline Vacuum L4 Sled Power L5 Beamline Vacuum L5 Sled...

  13. Ted B shop, PGA Derek Sprague, PGA

    E-Print Network [OSTI]

    Hemmers, Oliver

    and Superintendent to review operations/maintenance procedures, Model Golf Shop application. NOON a Evaluation team 451001 Las Vegas, NV 89154-1001 Dear President Smatresk: The Criteria and Standards for Accreditation and procedures ofthe program (policies and procedures for the golf course and golf shop should also be included

  14. Heavy Mobile Equipment Mechanic (One Mechanic Shop)

    Broader source: Energy.gov [DOE]

    The position is a Heavy Mobile Equipment Mechanic (One Mechanic Shop) located in Kent, Washington, and will be responsible for the safe and efficient operation of a field garage performing...

  15. JEA- ShopSmart Residential Rebate Program

    Broader source: Energy.gov [DOE]

    JEA is offering rebates for home energy efficiency improvements through the ShopSmart with JEA program. Appliance rebates are claimed through a mail-in rebate form, available on the program web...

  16. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Nancy Porter; Mike Sullivan; Chris Neary

    2003-05-01T23:59:59.000Z

    The two broad categories of deposited weld metal repair and fiber-reinforced composite repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repairs and for fiber-reinforced composite repair. To date, all of the experimental work pertaining to the evaluation of potential repair methods has focused on fiber-reinforced composite repairs. Hydrostatic testing was also conducted on four pipeline sections with simulated corrosion damage: two with composite liners and two without.

  17. Bugs in Your Shopping Cart:Bugs in Your Shopping Cart: A TaxonomyA Taxonomy

    E-Print Network [OSTI]

    Bugs in Your Shopping Cart:Bugs in Your Shopping Cart: A TaxonomyA Taxonomy Giri Vijayaraghavan-2002. Quality Week 2002 The Bug TaxonomyThe Bug Taxonomy · An outline that categorizes and lists a large number of potential bugs. · The tester who uses the taxonomy can sample from the list, selecting a potential problem

  18. Remote Food Shopping Robot System in a Supermarket Realization of the shopping task from remote places

    E-Print Network [OSTI]

    Ohya, Akihisa

    Remote Food Shopping Robot System in a Supermarket ­Realization of the shopping task from remote- ulating remote objects. This system attempts to answer the challenge of extending mobile robot potentials in a supermarket from a remote location using the Internet. We built the prototype system by integrating custom

  19. Biomass Company Sets Up Shop in High School Lab | Department...

    Broader source: Energy.gov (indexed) [DOE]

    Biomass Company Sets Up Shop in High School Lab Biomass Company Sets Up Shop in High School Lab March 30, 2010 - 2:45pm Addthis Stephen Graff Former Writer & editor for Energy...

  20. artisanal gold shops: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Millikelvin Lab OP105-112 Machine Shop OP132 Resistive Magnet Shop CICC Winding Area Transformers winding area and most of our resistive magnets, including the "45 T Hybrid"...

  1. Quality assurance in small plating shops

    SciTech Connect (OSTI)

    McNabb, W.J. (Electroless Nickel Plating of Louisiana, Hammond, LA (United States))

    1993-10-01T23:59:59.000Z

    The potential for electroless nickel coatings in oilfield and petrochemical applications is quite high. The greatest obstacle to their use has been a reputation for poor quality due to a lack of quality control in many plating shops. To overcome this, electroless nickel shops should not only have a quality control program in their operation, but must also document its use and success. This article describes how a plating shoe can develop the necessary procedures, manuals, and paperwork trail to offer quality assurance and to satisfy customers.

  2. PERFORMANCE EVALUATION OF A CONTROLLED FLOW-SHOP SYSTEM

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    --philippe.le-parc--frank.singhoff--lionel.marce}@univ-brest.fr Keywords: Assembly lines, flow-shop, control presents an original performance analysis applied to a flow-shop system driven by a set of local command-shop system whose control is jointly ensured by a set of local command units (pro- grammable logic controllers

  3. BYD Auto | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty EditCalifornia: EnergyAvignon, France: Energy ResourcesBurleyBLMUSFWSBPBYD Auto Jump

  4. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, Leo M. (Livermore, CA)

    1998-01-01T23:59:59.000Z

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find an the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was was heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past.

  5. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, L.M.

    1998-05-05T23:59:59.000Z

    Disclosed is a rapid road repair vehicle capable of moving over a surface to be repaired at near normal posted traffic speeds to scan for and find at the high rate of speed, imperfections in the pavement surface, prepare the surface imperfection for repair by air pressure and vacuum cleaning, applying a correct amount of the correct patching material to effect the repair, smooth the resulting repaired surface, and catalog the location and quality of the repairs for maintenance records of the road surface. The rapid road repair vehicle can repair surface imperfections at lower cost, improved quality, at a higher rate of speed than was not heretofor possible, with significantly reduced exposure to safety and health hazards associated with this kind of road repair activities in the past. 2 figs.

  6. Materials, Modules, and Systems: An Atoms to Autos Approach to...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Materials, Modules, and Systems: An Atoms to Autos Approach to Automotive Thermoelectric Systems Development Materials, Modules, and Systems: An Atoms to Autos Approach to...

  7. The Resurgence of America's Auto Industry

    ScienceCinema (OSTI)

    Zimmer, Stephen; Cischke, Sue;

    2013-05-29T23:59:59.000Z

    A look at how strategic investments and partnerships between the Energy Department and automakers have helped the American auto industry become a leader in advanced and fuel-efficient vehicles ? creating jobs and boosting profits in the process.

  8. Auto-associative nanoelectronic neural network

    SciTech Connect (OSTI)

    Nogueira, C. P. S. M.; Guimarães, J. G. [Departamento de Engenharia Elétrica - Laboratório de Dispositivos e Circuito Integrado, Universidade de Brasília, CP 4386, CEP 70904-970 Brasília DF (Brazil)

    2014-05-15T23:59:59.000Z

    In this paper, an auto-associative neural network using single-electron tunneling (SET) devices is proposed and simulated at low temperature. The nanoelectronic auto-associative network is able to converge to a stable state, previously stored during training. The recognition of the pattern involves decreasing the energy of the input state until it achieves a point of local minimum energy, which corresponds to one of the stored patterns.

  9. Investigating a Hybrid Metaheuristic for Job Shop Rescheduling

    E-Print Network [OSTI]

    Aickelin, Uwe

    annealing and the great deluge algorithm can improve the results when hybridised with our artificial immune scenarios. Keywords: Artificial immune systems, simulated annealing, great deluge algorithm, job shop

  10. General Orientation to the Building 433 LOM Machine Shop

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    press, and lathe) in a LOM Shop must be arranged through the APS Floor Coordinator. LOCKOUTTAGOUT Lockouttagout procedures must be coordinated through an APS Floor...

  11. Tips: Shopping for Appliances | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed off Energy.gov. Are you sure you want toworldPower 2010 1 TNews &Appliances Tips: Shopping for

  12. Tips: Shopping for Lighting | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed off Energy.gov. Are you sure you want toworldPower 2010 1 TNews &Appliances Tips: Shopping

  13. Tips: Shopping for Lighting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreakingMayDepartmentTest for PumpingThe| Department ofAirTips: Shopping for Lighting

  14. Solar Shop Australia | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty Edit with form HistoryRistmaSinosteelSolar Energy sro JumpProjects ServicesSolar Shop

  15. ENERGY STAR Back-To-School Shopping Checklist

    E-Print Network [OSTI]

    ENERGY STAR® Back-To-School Shopping Checklist Students can make a difference by shopping "smart" with ENERGY STAR® . Computing the Savings ENERGY STAR Qualified Computer Equipment Computer Monitor ENERGY up to 90 percent more energy than standard monitors. Printer If every home office were powered

  16. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Bill Bruce; Nancy Porter; George Ritter; Matt Boring; Mark Lozev; Ian Harris; Bill Mohr; Dennis Harwig; Robin Gordon; Chris Neary; Mike Sullivan

    2005-07-20T23:59:59.000Z

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. In lieu of a field installation on an abandoned pipeline, a preliminary nondestructive testing protocol is being developed to determine the success or failure of the fiber-reinforced liner pipeline repairs. Optimization and validation activities for carbon-fiber repair methods are ongoing.

  17. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-12-31T23:59:59.000Z

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. The first round of optimization and validation activities for carbon-fiber repairs are complete. Development of a comprehensive test plan for this process is recommended for use in the field trial portion of this program.

  18. Parallel auto-correlative statistics with VTK.

    SciTech Connect (OSTI)

    Pebay, Philippe Pierre [Kitware, France; Bennett, Janine Camille

    2013-08-01T23:59:59.000Z

    This report summarizes existing statistical engines in VTK and presents both the serial and parallel auto-correlative statistics engines. It is a sequel to [PT08, BPRT09b, PT09, BPT09, PT10] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, contingency, k-means, and order statistics engines. The ease of use of the new parallel auto-correlative statistics engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the autocorrelative statistics engine.

  19. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-08-17T23:59:59.000Z

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Principal conclusions from a survey of natural gas transmission industry pipeline operators can be summarized in terms of the following performance requirements for internal repair: (1) Use of internal repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) The most common size range for 80% to 90% of operators surveyed is 508 mm (20 in.) to 762 mm (30 in.), with 95% using 558.8 mm (22 in.) pipe. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is only marginally effective at restoring the pressure containing capabilities of pipelines. Failure pressures for larger diameter pipe repaired with a semi-circular patch of carbon fiber-reinforced composite lines were also marginally greater than that of a pipe section with un-repaired simulated damage without a liner. These results indicate that fiber reinforced composite liners have the potential to increase the burst pressure of pipe sections with external damage Carbon fiber based liners are viewed as more promising than glass fiber based liners because of the potential for more closely matching the mechanical properties of steel. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the field trial portion of this program.

  20. Rapid road repair vehicle

    DOE Patents [OSTI]

    Mara, Leo M. (Livermore, CA)

    1999-01-01T23:59:59.000Z

    Disclosed are improvments to a rapid road repair vehicle comprising an improved cleaning device arrangement, two dispensing arrays for filling defects more rapidly and efficiently, an array of pre-heaters to heat the road way surface in order to help the repair material better bond to the repaired surface, a means for detecting, measuring, and computing the number, location and volume of each of the detected surface imperfection, and a computer means schema for controlling the operation of the plurality of vehicle subsystems. The improved vehicle is, therefore, better able to perform its intended function of filling surface imperfections while moving over those surfaces at near normal traffic speeds.

  1. EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell...

    Office of Environmental Management (EM)

    EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles April 18, 2013 - 12:00am Addthis The...

  2. Auto/Steel Partnership: Hydroforming Materials and Lubricant...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lightweight Rear Chassis Structures Future Generation Passenger Compartment AutoSteel Partnership: Hydroforming Materials and Lubricant Lightweight Rear Chassis Structures...

  3. INTERNAL REPAIR OF PIPELINES

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; Nancy Porter; Mike Sullivan; Chris Neary

    2004-04-12T23:59:59.000Z

    The two broad categories of deposited weld metal repair and fiber-reinforced composite liner repair technologies were reviewed for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Preliminary test programs were developed for both deposited weld metal repair and for fiber-reinforced composite liner repair. Evaluation trials have been conducted using a modified fiber-reinforced composite liner provided by RolaTube and pipe sections without liners. All pipe section specimens failed in areas of simulated damage. Pipe sections containing fiber-reinforced composite liners failed at pressures marginally greater than the pipe sections without liners. The next step is to evaluate a liner material with a modulus of elasticity approximately 95% of the modulus of elasticity for steel. Preliminary welding parameters were developed for deposited weld metal repair in preparation of the receipt of Pacific Gas & Electric's internal pipeline welding repair system (that was designed specifically for 559 mm (22 in.) diameter pipe) and the receipt of 559 mm (22 in.) pipe sections from Panhandle Eastern. The next steps are to transfer welding parameters to the PG&E system and to pressure test repaired pipe sections to failure. A survey of pipeline operators was conducted to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. Completed surveys contained the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water, in difficult soil conditions, under highways, under congested intersections, and under railway crossings. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem. (3) Typical travel distances can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). All three groups require pig-based systems. A despooled umbilical system would suffice for the first two groups which represents 81% of survey respondents. The third group would require an onboard self-contained power unit for propulsion and welding/liner repair energy needs. (4) Pipe diameter sizes range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.). The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.), with 95% using 558.8 mm (22 in.) pipe. An evaluation of potential repair methods clearly indicates that the project should continue to focus on the development of a repair process involving the use of GMAW welding and on the development of a repair process involving the use of fiber-reinforced composite liners.

  4. VRIJE UNIVERSITEIT AMSTERDAM Auto-tuning a LOFAR radio

    E-Print Network [OSTI]

    van Nieuwpoort, Rob V.

    VRIJE UNIVERSITEIT AMSTERDAM Auto-tuning a LOFAR radio astronomy pipeline in JavaCL Author Jan Kis experiments. However, designing the actual software that would give optimal performance for many dif- ferent auto-tuning to find the optimal solution. Auto-tuning is based on a construction of a more generic

  5. HEART SMART NUTRITION Heart Smart Shopping & Label Reading

    E-Print Network [OSTI]

    Lesson 3 HEART SMART NUTRITION Heart Smart Shopping & Label Reading What's the first step in fat. Your goal is to eat a diet lower in saturated fat, trans fat, and cholesterol. The National Heart

  6. Business expansion and lean transformation for helicopter blade shop

    E-Print Network [OSTI]

    Bar, S. Neil (Saumen Neil)

    2006-01-01T23:59:59.000Z

    Sikorsky Aircraft is undergoing a lean transformation as its helicopter blade line is relocated from Stratford to Site B. Value Stream Mapping is a vital tool to eliminate sources of waste in the existing blade shop and ...

  7. Automobile Repair Shop In 1987, the Alaska Health Project has performed an audit of an automobile

    E-Print Network [OSTI]

    Part 268). 2) Disposal in a authorized high-temperature incinerator. 3) Disposal to an authorized assumes incineration is the disposal method. If the waste is disposed of in a landfill or by recycling, costs may be reduced. However, considering the new solvent ban on land disposal incineration

  8. Regression models Consequences of auto-generation

    E-Print Network [OSTI]

    McCullagh, Peter

    with conventional models 2 Consequences of auto-generation Sampling bias Volunteer samples Joint distributions of Y into two components x1(u) = (variety(u), treatment(u), . . .) affecting the mean x2(u) = (block; ) = Nn(X1, 2 0In + 2 1K[x2])(A) A Rn, K[x] = {K(xi, xj)} block-factor models: K(i, j) = 1 if block

  9. Window Replacement, Rehabilitation, & Repair Guides - Building...

    Energy Savers [EERE]

    Window Replacement, Rehabilitation, & Repair Guides - Building America Top Innovation Window Replacement, Rehabilitation, & Repair Guides - Building America Top Innovation Effec...

  10. Rebuilding the American Auto Industry | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    was the right choice -- and the future is bright. Addthis Related Articles Fisker, Tesla, and American Auto Innovation Moniz: Tesla Repayment Shows the Strength of Energy...

  11. Auto/Steel Partnership: AHSS Stamping, Strain Rate Characterization...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AHSS Stamping, Strain Rate Characterization, Sheet Steel Fatigue, AHSS Joining AutoSteel Partnership: AHSS Stamping, Strain Rate Characterization, Sheet Steel Fatigue, AHSS...

  12. Auto/Steel Partnership: Fatigue of AHSS Strain Rate Characterization...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fatigue of AHSS Strain Rate Characterization AutoSteel Partnership: Fatigue of AHSS Strain Rate Characterization 2009 DOE Hydrogen Program and Vehicle Technologies Program Annual...

  13. Auto/Steel Partnership: Advanced High-Strength Steel Research...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Advanced High-Strength Steel Research and Development AutoSteel Partnership: Advanced High-Strength Steel Research and Development 2009 DOE Hydrogen Program and Vehicle...

  14. PERI Auto-tuning Memory Intensive Kernels

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for RenewableSpeedingBiomass and4/26/11: eliza18 emergency3 , 2 015PERI - Auto-tuning

  15. Grande Wi-Fi : understanding what Wi-Fi users are doing in coffee-shops

    E-Print Network [OSTI]

    Gupta, Neeti

    2004-01-01T23:59:59.000Z

    The relationship between coffee-shops and Internet has recently been highlighted by the launch of wireless "hotspots" which provides e-access through Wi-Fi technology, in coffee-shops and several other public places in ...

  16. Lean strategies for future body shop development and operation in the automotive industry by Iker Marcaide.

    E-Print Network [OSTI]

    Marcaide, Iker

    2010-01-01T23:59:59.000Z

    There are several body shops which are similar by size of workforce, level of utilization and product complexity but which differ considerably by investment required, shop size, uptime, inventory levels and quality ...

  17. OHS 11-066, 5-11-11 SHOP AREA INSPECTION CHECKLIST

    E-Print Network [OSTI]

    , No, or N/A. Be sure to retain all documentation regarding inspections-11-11 SHOP AREA INSPECTION CHECKLIST Building & Room: Inspected By: Shop Supervisor: Date: All locations

  18. Remote Shopping Robot System -Development of a hand mechanism for grasping fresh foods in a supermarket

    E-Print Network [OSTI]

    Ohya, Akihisa

    supermarkets, in this research, we propose "remote shopping robot system" as a concrete application efficiency. II. REMOTE SHOPPING ROBOT SYSTEM A. Concept In the case of industrial products, objects haveRemote Shopping Robot System -Development of a hand mechanism for grasping fresh foods

  19. A CONSTANT-INVENTORY TACTICAL PLANNING MODEL FOR A JOB SHOP

    E-Print Network [OSTI]

    Graves, Stephen C.

    A CONSTANT-INVENTORY TACTICAL PLANNING MODEL FOR A JOB SHOP Stephen C. Graves Massachusetts a constant-inventory tactical planning model for a generic manufacturing system, such as a job shop assume that we can regulate the release of work to the shop to maintain the constant-inventory constraint

  20. How do foreign auto suppliers need to compete differently in China market?

    E-Print Network [OSTI]

    Jin, Hao (Hao Howard)

    2006-01-01T23:59:59.000Z

    The China auto market is surging as the most fascinating place for the global auto industry today. All major foreign auto OEMs have been aggressively expanding their business in China, and expecting most of their global ...

  1. PROBABILISTIC AUTO-ASSOCIATIVE MODELS AND SEMI-LINEAR PCA

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    to this family of approaches, non-linear transformation of the original data set [7, 3] too. The auto-associative neural networks can also be view as a non-linear PCA model [2, 27, 4, 19]. In [13] we propose the auto that the projection function is linear and let the regression function be arbitrary. We call the resulting AAM

  2. Instruction Guide Shopping Using the Product Keyword Search

    E-Print Network [OSTI]

    Sheremet, Alexandru

    powerful search engine. Start with by entering an item into the search field and follow the steps outlined the Home/Shop tab at the top to start your search 3. To start searching for an item, enter the item in the search field ­ include specific search terms, such as "latex-free gloves" instead of just "gloves

  3. Performance Optimization and Auto-Tuning

    SciTech Connect (OSTI)

    Howison, Mark

    2012-10-01T23:59:59.000Z

    In the broader computational research community, one subject of recent research is the problem of adapting algorithms to make effective use of multi- and many-core processors. Effective use of these architectures, which have complex memory hierarchies with many layers of cache, typically involves a careful examination of how an algorithm moves data through the memory hierarchy. Unfortunately, there is often a non-obvious relationship between algorithmic parameters like blocking strategies, and their impact on memory utilization, and, in turn, the relationship with runtime performance. Auto-tuning is an empirical method used to discover optimal values for tunable algorithmic parameters under such circumstances. The challenge is compounded by the fact that the settings that produce the best performance for a given problem and a given platform may not be the best for a different problem on the same platform, or the same problem on a different platform. The high performance visualization research community has begun to explore and adapt the principles of auto-tuning for the purpose of optimizing codes on modern multi- and many-core processors. This report focuses on how performance optimization studies reveal a dramatic variation in performance for two fundamental visualization algorithms: one based on a stencil operation having structured, uniform memory access, and the other is ray casting volume rendering, which uses unstructured memory access patterns. The two case studies highlighted in this report show the extra effort required to optimize such codes by adjusting the tunable algorithmic parameters can return substantial gains in performance. Additionally, these case studies also explore the potential impact of and the interaction between algorithmic optimizations and tunable algorithmic parameters, along with the potential performance gains resulting from leveraging architecture-specific features.

  4. Industrial motor repair in the United States

    SciTech Connect (OSTI)

    Schueler, V.; Leistner, P.; Douglass, J.

    1994-09-01T23:59:59.000Z

    This report characterizes the motor repair industry in the United States; summarizes current motor repair and testing practice; and identifies barriers to energy motor repair practice and recommends strategies for overcoming those barriers.

  5. Automatic Performance Collection (AutoPerf) | Argonne Leadership...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Automatic Performance Collection (AutoPerf) A beta version of a tool for the automatic collection of hardware performance counter and MPI information has been installed on ALCF BG...

  6. auto reversed r-22: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    alla L.R. 221997 che imponeva di adottare il Piano Regiona Cinzano, Pierantonio 2 In Helicobacter pylori auto-inducer-2, but not LuxSMccAB catalysed reverse...

  7. auto diffusion function: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    angle of 30mathrm o are investigated. The analysis reveals that the influ... Sun, Y 2005-01-01 3 Etude par diffusion de Huang des auto-interstitiels dans un alliage...

  8. Secretary Chu Speaks at the 2010 Washington Auto Show

    Broader source: Energy.gov [DOE]

    at the 2010 Washington Auto Show, Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need. He also announced that the Department of Energy had...

  9. ACADEMIC MACHINE SHOP SAFETY Procedure: 6.01 Created: 7/2011 Version: 2.0 Revised: 9/30/2013

    E-Print Network [OSTI]

    Jia, Songtao

    in the machine shop. d. Must use "Buddy System" when working in the shop. e. Must report all injuries to the ShopACADEMIC MACHINE SHOP SAFETY Procedure: 6.01 Created: 7/2011 Version: 2.0 Revised: 9, staff and visitors working in any Academic Machine Shop. It defines safety guidelines, training

  10. Polarization imaging apparatus with auto-calibration

    DOE Patents [OSTI]

    Zou, Yingyin Kevin; Zhao, Hongzhi; Chen, Qiushui

    2013-08-20T23:59:59.000Z

    A polarization imaging apparatus measures the Stokes image of a sample. The apparatus consists of an optical lens set, a first variable phase retarder (VPR) with its optical axis aligned 22.5.degree., a second variable phase retarder with its optical axis aligned 45.degree., a linear polarizer, a imaging sensor for sensing the intensity images of the sample, a controller and a computer. Two variable phase retarders were controlled independently by a computer through a controller unit which generates a sequential of voltages to control the phase retardations of the first and second variable phase retarders. A auto-calibration procedure was incorporated into the polarization imaging apparatus to correct the misalignment of first and second VPRs, as well as the half-wave voltage of the VPRs. A set of four intensity images, I.sub.0, I.sub.1, I.sub.2 and I.sub.3 of the sample were captured by imaging sensor when the phase retardations of VPRs were set at (0,0), (.pi.,0), (.pi.,.pi.) and (.pi./2,.pi.), respectively. Then four Stokes components of a Stokes image, S.sub.0, S.sub.1, S.sub.2 and S.sub.3 were calculated using the four intensity images.

  11. An empirical investigation of AutoCAD user interfaces 

    E-Print Network [OSTI]

    Flores, Patricia Laura

    1992-01-01T23:59:59.000Z

    Chair of Advisory Committee: Dr. Deborah A. Mitts This research examined human performance in a computer aided design scenario. Human performance with respect to two AutoCAD user interfaces (Menu and Template) and three AutoCAD task types (drawing... of the few human-computer interaction (HCI) scenarios for which relatively well-developed measures of human performance are not specified (Cuomo and Sharit, 1989). Previous research efforts have focused on measuring hutnan performance in terms of cognitive...

  12. Action Memorandum for Decommissioning of TAN-607 Hot Shop Area

    SciTech Connect (OSTI)

    M. A. Pinzel

    2007-05-01T23:59:59.000Z

    The Department of Energy is documenting the selection of an alternative for the TAN-607 Hot Shop Area using a Comprehensive Environmental Response, Compensation, and Liability Act non-time-critical removal action (NTCRA). The scope of the removal action is limited to TAN-607 Hot Shop Area. An engineering evaluation/cost analysis (EE/CA) has assisted the Department of Energy Idaho Operations Office in identifuomg the most effective method for performing the decommissioning of this structure whose mission has ended. TAN-607 Hot Shop Area is located at Test Area North Technical Support Facility within the Idaho National Laboratory Site. The selected alternative consists of demolishing the TAN-607 aboveground structures and components, removing belowground noninert components (e.g. wood products), and removing the radiologically contaminated debris that does not meet remedial action objectives (RAOs), as defined in the Record of Decision Amendment for the V-Tanks and Explanation of Significant Differences for the PM-2A Tanks at Test Area North, Operable Unit 1-10.

  13. 5 Objektorientierung in Java, Teil 2 5.9 Object und Class 5-28 Objektorientierung/Autos/11-equals-clone-toString/Auto.java

    E-Print Network [OSTI]

    Arndt, Holger

    meinPKW = new Auto(); 74 Auto bmw = new Auto(); 75 Auto zweiCV; 76 77 // Identitaet und Aequivalenz mit == und equals() 78 meinPKW.fahren(100); 79 bmw.fahren(100); 80 System.out.println(bmw == meinPKW); // false 81 System.out.println(bmw.equals(meinPKW)); // true 82 bmw.fahren(100); 83 System.out.println(bmw

  14. Mammalian DNA Repair. Final Report

    SciTech Connect (OSTI)

    None

    2003-01-24T23:59:59.000Z

    The Gordon Research Conference (GRC) on Mammalian DNA Repair was held at Harbortown Resort, Ventura Beach, CA. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

  15. Inspect and Repair Steam Traps

    SciTech Connect (OSTI)

    Not Available

    2006-01-01T23:59:59.000Z

    This revised ITP tip sheet on inspecting and repairing steam traps provide how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.

  16. Record of Decision/Remedial Alternative Selection for the Motor Shops Seepage Basin (716-A)

    SciTech Connect (OSTI)

    Palmer, E.

    1999-02-03T23:59:59.000Z

    This decision document presents the selected remedial alternative for the Motor Shops Seepage Basin located at the Savannah River Site in Aiken, South Carolina

  17. Auto Indexer Auto-Indexer for Percussive Hammers: Vane Motor Dynamometer Testing

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Su, Jiann

    The development of the motor will help to achieve program technical objectives by improving well construction capabilities. This includes enabling high-temperature drilling as well as enhancing directional drilling. A key component in the auto indexer is the drive motor. It is an air-driven vane motor that converts the energy stored in the compressed air to mechanical energy. The motor is attached to hammer-like components which impart an impulsive load onto the drive shaft. The impulsive force on the drive shaft in turn creates an indexing action. A controlled test was performed to characterize the performance of the the vane motor for a given pressure. The Sandia dynamometer test station was used to determine the performance of the motor for a given input pressure.

  18. Property:Building/FloorAreaShops | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal PwerPerkins County, Nebraska:Precourt InstituteFloorAreaOffices JumpFloorAreaShops Jump to:

  19. Remote Shopping Robot System for Fresh Foods Development of the foods grasping mechanism

    E-Print Network [OSTI]

    Ohya, Akihisa

    Remote Shopping Robot System for Fresh Foods ­Development of the foods grasping mechanism­ Tetsuo) Abstract-- Our purpose is developing the remote shopping system as a concrete application. A human uses the system to select and buy fresh foods of a supermarket from a remote location via the Internet. We

  20. Discovering from tradition : lessons for new shopping center designs in Beijing, drawn from the traditional Da Shi-la shopping district

    E-Print Network [OSTI]

    Wang, Qian

    1995-01-01T23:59:59.000Z

    Since the 1979 Open Door policy, there have been the tensions between the illusion of far reaching advancement and the reality that basic provisions are scarce. Reflected in modem shopping designs in Beijing, this phenomenon ...

  1. Ping-pong auto-zero amplifier with glitch reduction

    DOE Patents [OSTI]

    Larson, Mark R. (Maple Grove, MN)

    2008-01-22T23:59:59.000Z

    A ping-pong amplifier with reduced glitching is described. The ping-pong amplifier includes a nulling amplifier coupled to a switching network. The switching network is used to auto-zero a ping amplifier within a ping-pong amplifier. The nulling amplifier drives the output of a ping amplifier to a proper output voltage level during auto-zeroing of the ping amplifier. By being at a proper output voltage level, glitches associated with transitioning between a ping amplifier and a pong amplifier are reduced or eliminated.

  2. Waste Minimization Plans and activities in the MFD Plating Shop

    SciTech Connect (OSTI)

    Dini, J.W.; Steffani, C.P.

    1991-02-01T23:59:59.000Z

    The Plating Shop (Building 322), provides processes such as electroplating, electroless plating, anodizing, cleaning, etching, electroforming and chemical milling. We in MFD are committed to an active program on waste minimization, and the purpose of this document is to outline the plan of action. Our short range minimization goals are threefold: (1) Reduce our major waste stream by 90%, (2) Minimize discharge of rinse water to sewer system, and (3) Eliminate vapor degreasing in the shop. The intermediate goals consist of characterizing the waste streams and evaluating recovery processes. To do this, we first need to have the distillation unit operational and time to determine its effectiveness. If it proves to be as effective as we anticipate, we will perhaps purchase a second unit. Regardless, the streams that we can identify include: nickel, copper, rinses, acids, alkalies, electropolish and miscellaneous. Our goal is to utilize electrolytic processes to recover metals such as nickel and copper and processes such as ion exchange for some of the other streams. We intend to evaluate the full gamut of recycling processes available for these streams. We anticipate completing this phase of the minimization program by January 1993. The long range goal is zero discharge or since this could prove extremely difficult, development of processes that will allow us to produce a sludge cake that could be handled by our Hazardous Waste Management Group.

  3. T-699: EMC AutoStart Buffer Overflows Let Remote Users Execute...

    Broader source: Energy.gov (indexed) [DOE]

    99: EMC AutoStart Buffer Overflows Let Remote Users Execute Arbitrary Code T-699: EMC AutoStart Buffer Overflows Let Remote Users Execute Arbitrary Code August 23, 2011 - 3:35pm...

  4. The AutoMed Schema Integration Repository Michael Boyd, Peter M c . Brien and Nerissa Tong

    E-Print Network [OSTI]

    McBrien, Peter

    The AutoMed Schema Integration Repository Michael Boyd, Peter M c . Brien and Nerissa Tong {mboyd,pjm

  5. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    SciTech Connect (OSTI)

    Secretary Chu

    2009-07-16T23:59:59.000Z

    Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of green jobs while helping reduce the nation’s dangerous dependence on foreign oil. The first three auto loans for advanced technologies were awarded to Ford Motor Company, Nissan Motors and Tesla Motors.

  6. Sec. Chu Announces the First Auto Loans for Advanced Technologies

    ScienceCinema (OSTI)

    Secretary Chu

    2010-09-01T23:59:59.000Z

    Energy Secretary Steven Chu announced $8 billion in conditional loan commitments for the development of innovative, advanced vehicle technologies that will create thousands of green jobs while helping reduce the nation?s dangerous dependence on foreign oil. The first three auto loans for advanced technologies were awarded to Ford Motor Company, Nissan Motors and Tesla Motors.

  7. Auto-Generation of Communication Benchmark Traces Vivek Deshpande

    E-Print Network [OSTI]

    Mueller, Frank

    Auto-Generation of Communication Benchmark Traces Vivek Deshpande North Carolina State University.edu Frank Mueller North Carolina State University Raleigh, NC, USA mueller@cs.ncsu.edu ABSTRACT Benchmarks creation is a tedious manual process. As a result, benchmarks tend to lag behind the development of complex

  8. AutoMotive technology College of Rural and Community Development

    E-Print Network [OSTI]

    Hartman, Chris

    to become an entry-level automotive tech- nician. The automotive service industry is constantly changingAutoMotive technology College of Rural and Community Development Community and Technical College 907-455-2932 www.ctc.uaf.edu/programs/Automotive/ certificate Minimum Requirements for Certificate: 34

  9. Spectra of empirical auto-covariance matrices R. Kuhn and P. Sollich

    E-Print Network [OSTI]

    Kühn, Reimer

    densities of large sample auto-covariance matrices of stationary stochastic processes at fixed ratio = N the properties of sta- tionary stochastic processes [1], one typically begins by concentrating on low the latter further consists in looking at the auto-covariance matrix obtained by sam- pling the auto

  10. Auto-Adaptive Fault Tolerant Control of a Seven-phase Drive

    E-Print Network [OSTI]

    Boyer, Edmond

    Auto-Adaptive Fault Tolerant Control of a Seven-phase Drive Xavier KESTELYN, Yvan CREVITS and Eric.Kestelyn@ensam.eu Abstract- This paper proposes an auto-adaptive current control that makes possible to reduce torque ripples references are not recomputed and the control scheme used in normal mode is auto-adapted in order to run

  11. Verification of Motor Repair Quality

    E-Print Network [OSTI]

    Butler, K.

    Motor testing at Advanced Energy has shown that a motor that has not suffered irreparable damage as a result of failure can be repaired to perform as well as before the failure. But the only way to achieve the performance level of an energy...

  12. DockingShop: A Tool for Interactive Molecular Docking

    SciTech Connect (OSTI)

    Lu, Ting-Cheng; Max, Nelson L.; Ding, Jinhui; Bethel, E. Wes; Crivelli, Silvia N.

    2005-04-24T23:59:59.000Z

    Given two independently determined molecular structures, the molecular docking problem predicts the bound association, or best fit between them, while allowing for conformational changes of the individual molecules during construction of a molecular complex. Docking Shop is an integrated environment that permits interactive molecular docking by navigating a ligand or protein to an estimated binding site of a receptor with real-time graphical feedback of scoring factors as visual guides. Our program can be used to create initial configurations for a protein docking prediction process. Its output--the structure of aprotein-ligand or protein-protein complex--may serve as an input for aprotein docking algorithm, or an optimization process. This tool provides molecular graphics interfaces for structure modeling, interactive manipulation, navigation, optimization, and dynamic visualization to aid users steer the prediction process using their biological knowledge.

  13. TAN Hot Shop and Support Facility Utilization Study

    SciTech Connect (OSTI)

    Picker, B.A.

    2001-11-16T23:59:59.000Z

    Impacts to the U.S. Department of Energy (DOE) complex caused by early closure (prior to 2018) and Demolition and Dismantlement (D and D) of the Test Area North (TAN) hot shop and its support facilities are explored in this report. Various possible conditions, such as Standby, Safe Store and Lay-up, that the facility may be placed in prior to eventually being turned over to D and D are addressed. The requirements, impacts, and implications to the facility and to the DOE Complex are discussed for each condition presented in the report. Some details of the report reference the Idaho National Engineering and Environmental Laboratory (INEEL) Spent Nuclear Fuel Life Cycle Baseline Plan, the INEEL 2000 Infrastructure Long Range Plan, and other internal INEEL reports.

  14. TAN HOT SHOP AND SUPPORT FACILITY UTILIZATION STUDY

    SciTech Connect (OSTI)

    Phillips, Ken Crawforth

    2001-11-01T23:59:59.000Z

    Impacts to the U.S. Department of Energy (DOE) complex caused by early closure (prior to 2018) and Demolition and Dismantlement (D&D) of the Test Area North (TAN) hot shop and its support facilities are explored in this report. Various possible conditions, such as Standby, Safe Store and Lay-up, that the facility may be placed in prior to eventually being turned over to D&D are addressed. The requirements, impacts, and implications to the facility and to the DOE Complex are discussed for each condition presented in the report. Some details of the report reference the Idaho National Engineering and Environmental Laboratory (INEEL) Spent Nuclear Fuel Life Cycle Baseline Plan, the INEEL 2000 Infrastructure Long Range Plan, and other internal INEEL reports.

  15. New Lighting Facts Label: Takes the Guess Work Out of Shopping...

    Office of Environmental Management (EM)

    cost for the year, and the color of the light (from warmyellowish, to white to coolblue). Download our placard Lumens: the new way to shop for light to see how to use the...

  16. Argonne/EPA system captures mercury from air in gold shops |...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the mercury vaporizes. The vaporized mercury is directed outside the shop into the open air where it descends onto homes, water and food of the local populations. Image credit:...

  17. Development of an NC equipment level controller in a hierarchical shop floor control system

    E-Print Network [OSTI]

    Chang, William

    1993-01-01T23:59:59.000Z

    of meeting cost, quality, variety and time constraints imposed by markets[2]. Obviously, allocating resources, directing part flow, and coordinating shop floor activities in a manufacturing environment are complex and interact with each other and requiring...

  18. Secretary Chu Speaks at the 2010 Washington Auto Show

    SciTech Connect (OSTI)

    Secretary Chu

    2010-02-03T23:59:59.000Z

    Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need at the 2010 Washington Auto Show. He also announced that the Department of Energy had closed on a $1.4 billion loan to Nissan to build the all-electric LEAF in Tennessee and create up to 1,300 American jobs.

  19. Secretary Chu Speaks at the 2010 Washington Auto Show

    ScienceCinema (OSTI)

    Secretary Chu

    2010-09-01T23:59:59.000Z

    Secretary Chu lays out a roadmap for how the U.S. can lead the world in making the clean vehicles we need at the 2010 Washington Auto Show. He also announced that the Department of Energy had closed on a $1.4 billion loan to Nissan to build the all-electric LEAF in Tennessee and create up to 1,300 American jobs.

  20. The Gordon conference on mammalian DNA repair

    SciTech Connect (OSTI)

    Cleaver, J.E.; Smerdon, M.J.

    1993-12-31T23:59:59.000Z

    A brief overview of the Gordon Conference on Mammalian Repair held February 1-5, 1993 in Ventura, California is presented.

  1. RCRA Facility Investigation/Remedial Investigation Report with the Baseline Risk Assessment for the 716-A Motor Shops Seepage Basin

    SciTech Connect (OSTI)

    Palmer, E.

    1997-08-25T23:59:59.000Z

    This document describes the RCRA Facility Investigation/Remedial Investigation/Baseline Risk Assessment of the 716-A Motor Shops Seepage Basin.

  2. Role of DNA repair protein ERCC1 in skin cancer 

    E-Print Network [OSTI]

    Song, Liang

    2009-01-01T23:59:59.000Z

    Nucleotide excision repair (NER) is one of the major repair systems for removal of DNA lesions. The NER pathway has evolved mainly to repair UV-induced DNA damage and is also active against a broad range of endogenously ...

  3. The feasibility of electrophoretic repair of impoundment leaks

    E-Print Network [OSTI]

    Han, Ji-Seok

    2002-01-01T23:59:59.000Z

    finding, repairing and testing the leaks, are tedious, expensive, and dangerous to workers. Electrophoretic repair technique is an innovative, economic, and safe method to repair the leakage of impoundments. A suspension of clay particles is induced...

  4. Automotive Repair by Number Theory Bart Snapp and Chris Snapp

    E-Print Network [OSTI]

    Snapp, Bart

    Automotive Repair by Number Theory Bart Snapp and Chris Snapp While repairing the ignition switch on a 1981 Fiat Spider, we discovered the following connection between number theory and automotive repair

  5. 3-D printed Shelby Cobra highlights ORNL R&D at Detroit Auto...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    automotive icon, the Department of Energy's Oak Ridge National Laboratory is showcasing additive manufacturing research at the 2015 North American International Auto Show in...

  6. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William

    2010-04-27T23:59:59.000Z

    Methods for promoting and suppressing auto-induction of transcription of cloned DNA in cultures of T7 expression strains are disclosed.

  7. Fisker, Tesla, and American Auto Innovation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport inEnergy June 6-7, 2013 MeetingEA #FebruaryFisker, Tesla, and American Auto

  8. Shanghai Jieneng Auto Technology Co Ltd | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty Edit with form HistoryRistma AGShandong Lusa New Energy CoShanghai Jieneng Auto

  9. Overview: STEEL Auto/Steel Partnership | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOrigin of Contamination in ManyDepartmentOutreachDepartment ofProgram |Department ofAuto/Steel

  10. Auto Indexer for Percussive Hammers | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureComments from TarasaName4ServicesTribal RenewableAustinAuto Indexer for

  11. Auto/Steel Partnership: AHSS Stamping, Strain Rate Characterization, Sheet

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureComments from TarasaName4ServicesTribal RenewableAustinAuto Indexer

  12. Auto/Steel Partnership: Fatigue of AHSS Strain Rate Characterization |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureComments from TarasaName4ServicesTribal RenewableAustinAutoDepartment of

  13. Auto/Steel Partnership: Hydroforming Materials and Lubricant Lightweight

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureComments from TarasaName4ServicesTribal RenewableAustinAutoDepartment

  14. EERE and Auto Manufacturers Demonstrate and Evaluate Fuel Cell Vehicles |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the YouTube|6721 Federal Register / Vol. 73,H Model SeniorDepartment of Energy and Auto

  15. Auto industry steel project to boost efficiency, safety

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumni AlumniFederalAshley BoyleAnL-15-08MediaAugust 3Auto

  16. INTERNAL REPAIR OF PIPELINES REVIEW & EVALUATION OF INTERNAL PIPELINE REPAIR TRIALS REPORT

    SciTech Connect (OSTI)

    Robin Gordon; Bill Bruce; Ian Harris; Dennis Harwig; George Ritter; Bill Mohr; Matt Boring; Nancy Porter; Mike Sullivan; Chris Neary

    2004-09-01T23:59:59.000Z

    The two broad categories of fiber-reinforced composite liner repair and deposited weld metal repair technologies were reviewed and evaluated for potential application for internal repair of gas transmission pipelines. Both are used to some extent for other applications and could be further developed for internal, local, structural repair of gas transmission pipelines. Evaluation trials were conducted on pipe sections with simulated corrosion damage repaired with glass fiber-reinforced composite liners, carbon fiber-reinforced composite liners, and weld deposition. Additional un-repaired pipe sections were evaluated in the virgin condition and with simulated damage. Hydrostatic failure pressures for pipe sections repaired with glass fiber-reinforced composite liner were only marginally greater than that of pipe sections without liners, indicating that this type of liner is generally ineffective at restoring the pressure containing capabilities of pipelines. Failure pressure for pipe repaired with carbon fiber-reinforced composite liner was greater than that of the un-repaired pipe section with damage, indicating that this type of liner is effective at restoring the pressure containing capability of pipe. Pipe repaired with weld deposition failed at pressures lower than that of un-repaired pipe in both the virgin and damaged conditions, indicating that this repair technology is less effective at restoring the pressure containing capability of pipe than a carbon fiber-reinforced liner repair. Physical testing indicates that carbon fiber-reinforced liner repair is the most promising technology evaluated to-date. Development of a comprehensive test plan for this process is recommended for use in the next phase of this project.

  17. PERI - Auto-tuning Memory Intensive Kernels for Multicore

    SciTech Connect (OSTI)

    Bailey, David H; Williams, Samuel; Datta, Kaushik; Carter, Jonathan; Oliker, Leonid; Shalf, John; Yelick, Katherine; Bailey, David H

    2008-06-24T23:59:59.000Z

    We present an auto-tuning approach to optimize application performance on emerging multicore architectures. The methodology extends the idea of search-based performance optimizations, popular in linear algebra and FFT libraries, to application-specific computational kernels. Our work applies this strategy to Sparse Matrix Vector Multiplication (SpMV), the explicit heat equation PDE on a regular grid (Stencil), and a lattice Boltzmann application (LBMHD). We explore one of the broadest sets of multicore architectures in the HPC literature, including the Intel Xeon Clovertown, AMD Opteron Barcelona, Sun Victoria Falls, and the Sony-Toshiba-IBM (STI) Cell. Rather than hand-tuning each kernel for each system, we develop a code generator for each kernel that allows us to identify a highly optimized version for each platform, while amortizing the human programming effort. Results show that our auto-tuned kernel applications often achieve a better than 4X improvement compared with the original code. Additionally, we analyze a Roofline performance model for each platform to reveal hardware bottlenecks and software challenges for future multicore systems and applications.

  18. How to Use the Dimension Elite 3D Printer (in the Carnegie Mellon MechE Machine Shop)

    E-Print Network [OSTI]

    McGaughey, Alan

    How to Use the Dimension Elite 3D Printer (in the Carnegie Mellon MechE Machine Shop) The 3D printer is in the undergraduate area of the shop, by the safety glasses, lasercutters, etc. 2) Login to the computer beside the 3D printer using your Andrew username and password (Note: at the time

  19. Shop machinery users may encounter numerous potential hazards when in proximity to or working with hand tools and

    E-Print Network [OSTI]

    Straight, Aaron

    form or equivalent and retain for at least one year. · EH&S provides general safety training for shop-up ponytail, or hairnet). o Do not wear jewelry (rings, necklaces, etc.). Personal Protective Equipment (PPE. · Conduct periodic inspections using SU's Shop Area Inspection Checklist or equivalent. · Remove, tag (lock

  20. A New Architecture for Flexible Shop Control Systems* Gerrit Teunis, IFW, Paulo Leito CCP, Michael Madden, MCS

    E-Print Network [OSTI]

    Madden, Michael

    , "A Modular Shop Control Toolkit for Flexible Manufacturing". 1. Generation Mainframe propriatary hardA New Architecture for Flexible Shop Control Systems* Gerrit Teunis, IFW, Paulo Leitão CCP, Michael human involvement and empowerment. Modern manufacturing facilities must be flexible, to allow for rapid

  1. Evaluation of Sharpness Measures and Search Algorithms for the Auto-Focusing of High Magnification Images

    E-Print Network [OSTI]

    Abidi, Mongi A.

    -focusing is an indispensable function for imaging systems designed for such applications. This paper studies the feasibility of an image based passive auto-focusing control for high magnification systems based on off builds up the foundation for the development of auto-focusing schemes with particular applications

  2. The visualization of data and the user-interface in the Auto-ID World

    E-Print Network [OSTI]

    Chandrasekhar, Chaitra

    2005-01-01T23:59:59.000Z

    This thesis proposes a framework for user interface (UI) design in the Auto-ID world. The thesis includes the examination of issues related to visualizing data to the user from a top-down perspective in the Auto-ID World. ...

  3. Flexible Calibration : Minimal Cases for Auto-calibration Anders Heyden, Kalle strm

    E-Print Network [OSTI]

    Lunds Universitet

    Flexible Calibration : Minimal Cases for Auto-calibration Anders Heyden, Kalle �ström Centre This paper deals with the concept of auto-calibration, i.e. methods to calibrate a camera on reconstruction, called flexible calibration. The main theoretical results are that it is only needed to know

  4. Auto-Calibration of Cylindrical Multi-Projector Systems Behzad Sajadi

    E-Print Network [OSTI]

    Loudon, Catherine

    Auto-Calibration of Cylindrical Multi-Projector Systems Behzad Sajadi Department of Computer of California, Irvine ABSTRACT In this paper we present a novel technique to calibrate multiple ca- sually setup. To the best of our knowledge, this is the first method that can achieve accurate geometric auto-calibration

  5. Developments advance subsea pipelaying, inspection, repair

    SciTech Connect (OSTI)

    NONE

    1997-09-15T23:59:59.000Z

    Recent advances in laying, inspecting, and repairing pipelines are helping to cut both costs and time. A new dredging system that employs jets to clear a subsea trench for pipelay received trials off Belgium last spring. Also, within the last year, projects in the Middle East and North Sea employed technologies that promise to make inspecting the surface of a subsea pipeline in difficult terrain easier, less time consuming, and therefore less costly. Plus, subsea repair of damaged pipelines may take less time with a new ``stabbable`` pipe connector. The paper describes jet dredging, inspection advance, support software, the North Sea site, and pipeline repair.

  6. Clock Auto-synchronizing Method for BES III ETOF Upgrade

    E-Print Network [OSTI]

    Si-Yu, Wang; Shu-Bin, Liu; Qi, An

    2015-01-01T23:59:59.000Z

    An automatic clock synchronizing method implemented in field programmable gate array (FPGA) is proposed in this paper. It is developed for the clock system which will be applied in the end-cap time of flight (ETOF) upgrade of the Beijing Spectrometer (BESIII). In this design, an FPGA is used to automatically monitor the synchronization circuit and deal with signals coming from external clock synchronization circuit. By testing different delay time of the detection signal and analyzing state signals returned, the synchronization windows will be found automatically in FPGA. The new clock system not only retains low clock jitter which is less than 20ps root mean square (RMS), but also demonstrates automatic synchronization to the beam bunches. So far, the clock auto-synchronizing function has been working successfully under a series of tests. It will greatly simplify the system initialization and maintenance in the future.

  7. Clock Auto-synchronizing Method for BES III ETOF Upgrade

    E-Print Network [OSTI]

    Wang Si-Yu; Cao Ping; Liu Shu-Bin; An Qi

    2015-03-09T23:59:59.000Z

    An automatic clock synchronizing method implemented in field programmable gate array (FPGA) is proposed in this paper. It is developed for the clock system which will be applied in the end-cap time of flight (ETOF) upgrade of the Beijing Spectrometer (BESIII). In this design, an FPGA is used to automatically monitor the synchronization circuit and deal with signals coming from external clock synchronization circuit. By testing different delay time of the detection signal and analyzing state signals returned, the synchronization windows will be found automatically in FPGA. The new clock system not only retains low clock jitter which is less than 20ps root mean square (RMS), but also demonstrates automatic synchronization to the beam bunches. So far, the clock auto-synchronizing function has been working successfully under a series of tests. It will greatly simplify the system initialization and maintenance in the future.

  8. CATASTROPHIC REPAIR REQUEST CHECKLIST Office of Research

    E-Print Network [OSTI]

    Schladow, S. Geoffrey

    Not Meet Policy Not Sure Equipment may not be covered by a service contract that provides for repair Contacted: ______________ Amount of Annual Service Contract: $ ___________ Meets Policy Info Pending Does

  9. Reducing Your Leak Rate Without Repairing Leaks 

    E-Print Network [OSTI]

    Beals, C.

    2005-01-01T23:59:59.000Z

    As plant personnel know, repairing compressed air leaks can be an expensive, labor intensive and never-ending process. This article discusses ways plant personnel can reduce and maintain their leak rate at a lower level ...

  10. Vehicle Repair Policy Outline the policy regarding vehicle repair on University of Michigan (U-M) vehicles.

    E-Print Network [OSTI]

    Kirschner, Denise

    Vehicle Repair Policy Objective Outline the policy regarding vehicle repair on University of Michigan (U-M) vehicles. Policy 1. All vehicle repairs performed on U-M vehicles must be coordinated facility to repair their fleet vehicles. 2. U-M vehicles leased through Fleet Services include routine

  11. Energy and Technology Review: Unlocking the mysteries of DNA repair

    SciTech Connect (OSTI)

    Quirk, W.A.

    1993-04-01T23:59:59.000Z

    DNA, the genetic blueprint, has the remarkable property of encoding its own repair following diverse types of structural damage induced by external agents or normal metabolism. We are studying the interplay of DNA damaging agents, repair genes, and their protein products to decipher the complex biochemical pathways that mediate such repair. Our research focuses on repair processes that correct DNA damage produced by chemical mutagens and radiation, both ionizing and ultraviolet. The most important type of DNA repair in human cells is called excision repair. This multistep process removes damaged or inappropriate pieces of DNA -- often as a string of 29 nucleotides containing the damage -- and replaces them with intact ones. We have isolated, cloned, and mapped several human repair genes associated with the nucleotide excision repair pathway and involved in the repair of DNA damage after exposure to ultraviolet light or mutagens in cooked food. We have shown that a defect in one of these repair genes, ERCC2, is responsible for the repair deficiency in one of the groups of patients with the recessive genetic disorder xeroderma pigmentosum (XP group D). We are exploring ways to purify sufficient quantities (milligrams) of the protein products of these and other repair genes so that we can understand their functions. Our long-term goals are to link defective repair proteins to human DNA repair disorders that predispose to cancer, and to produce DNA-repair-deficient mice that can serve as models for the human disorders.

  12. Framing the Conversation: The Role of Facebook Conversations in Shopping for Eyeglasses

    E-Print Network [OSTI]

    Kane, Shaun K.

    Framing the Conversation: The Role of Facebook Conversations in Shopping for Eyeglasses Karim Said Warby Parker's Facebook page and explore the ways customers formulate questions and conversations,000 Facebook posts, consisting of photos, comments, and "likes". Using statistical analyses and qualitative

  13. Mathematical optimization of a flexible job shop problem including preventive maintenance and

    E-Print Network [OSTI]

    Patriksson, Michael

    1 Mathematical optimization of a flexible job shop problem including preventive maintenance as the scheduling problem includes limited availability of fixtures and preventive maintenance planning periodicity, a number of preventive maintenance activities need to be carried out in some of the resources

  14. Remote Shopping Robot System for Fresh Foods Method of handling foods

    E-Print Network [OSTI]

    Ohya, Akihisa

    Remote Shopping Robot System for Fresh Foods ­ Method of handling foods ­ Tetsuo TOMIZAWA, Akihisa a mobile manipulator as a teleoperated tool for accessing and manipulating remote objects. A human uses the system to select and buy fresh foods of a super market from a remote location via the Internet. We

  15. JOB SHOP SCHEDULING WITH DEADLINES Egon Balas, Carnegie Mellon University, Pittsburgh, PA, Usa

    E-Print Network [OSTI]

    Serafini, Paolo

    this problem is itself strongly NP-complete, it can nevertheless be solved efficiently in practice by a clever. The overall procedure is heuristic and exhibits a good trade-off between computing time and solution quality. The proposed model has all usual features of the well known Job Shop model with the addition of release dates

  16. Silicon nanowire boost for rechargeable batteries Online Shop Contact us Advanced

    E-Print Network [OSTI]

    Cui, Yi

    that of graphite and close to the theoretical maximum. The nanowire battery also maintained its capacity over 10Silicon nanowire boost for rechargeable batteries Online Shop Contact us Advanced search Chemistry batteries 17 December 2007 Scientists in the US have devised an easy way of using silicon nanowires

  17. HYDROGEN EFFECTS ON LASER ENGINEERED NET SHAPE (LENS) REPAIRED WELDMENTS

    SciTech Connect (OSTI)

    Korinko, P; Thad Adams, T

    2006-10-06T23:59:59.000Z

    New methods of repairing mis-machined components are always of interest. In this study, an innovative method using Laser Engineered Net Shape{trademark} (LENS{reg_sign}) forming was used to repair intentionally mis-machined test articles. The components were repaired and subsequently hydrogen charged and burst tested. The LENS repair did not have an adverse effect on the solid state weld process that was used to repair the components. Hydrogen charged samples failed in a similar manner to the uncharged samples. Overall, the prospects for LENS repairing similar products are favorable and further work is encouraged.

  18. Knock mitigation on boosted Controlled Auto-Ignition engines with fuel stratification and Exhaust Gas Recycling

    E-Print Network [OSTI]

    Sang, Wen, Ph. D. Massachusetts Institute of Technology

    2014-01-01T23:59:59.000Z

    This research is carried out to understand the mechanism of using fuel stratification and Exhaust Gas Recycling (EGR) for knock mitigation on boosted Controlled Auto-Ignition (CAl) engines. Experiments were first conducted ...

  19. The Effect of the 18-Year Old Drinking Age on Auto Accidents

    E-Print Network [OSTI]

    Cucchiaro, Stephen

    The effect of Massachusetts' reduced drinking age on auto accidents is examined by employing an interrupted time series analysis of monthly accident data covering the period January, 1969, through September 1973. The data ...

  20. E-Print Network 3.0 - auto control system Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Architecture Junya Morita Summary: shows goals as blue dots. If the center of the vehicle is off the optimal line, the auto control system... the arrow key on the keyboard...

  1. AutoMoDe - Model-Based Development of Automotive Software

    E-Print Network [OSTI]

    Ziegenbein, Dirk; Freund, Ulrich; Bauer, Andreas; Romberg, Jan; Schatz, Bernhard

    2011-01-01T23:59:59.000Z

    This paper describes first results from the AutoMoDe (Automotive Model-Based Development) project. The overall goal of the project is to develop an integrated methodology for model-based development of automotive control software, based on problem-specific design notations with an explicit formal foundation. Based on the existing AutoFOCUS framework, a tool prototype is being developed in order to illustrate and validate the key elements of our approach.

  2. Repairable chip bonding/interconnect process

    DOE Patents [OSTI]

    Bernhardt, Anthony F. (Berkeley, CA); Contolini, Robert J. (Livermore, CA); Malba, Vincent (Livermore, CA); Riddle, Robert A. (Tracy, CA)

    1997-01-01T23:59:59.000Z

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder.

  3. Repairable chip bonding/interconnect process

    DOE Patents [OSTI]

    Bernhardt, A.F.; Contolini, R.J.; Malba, V.; Riddle, R.A.

    1997-08-05T23:59:59.000Z

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules is disclosed. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder. 10 figs.

  4. SNL Researchers Assess Wind Turbine Blade Inspection and Repair...

    Office of Environmental Management (EM)

    Researchers Assess Wind Turbine Blade Inspection and Repair Methods SNL Researchers Assess Wind Turbine Blade Inspection and Repair Methods May 18, 2015 - 5:32pm Addthis A picture...

  5. Phonemic Categorization and Phonotactic Repair as Parallel Sublexical Processes 

    E-Print Network [OSTI]

    Ishikawa, Kiyoshi

    2014-07-01T23:59:59.000Z

    categorization and phonotactic repair are sublexical and simultaneous; phonotactic repairs themselves depend on coarticulation cues. Such models can be implemented in two different versions: suprasegmental matching, according to which a speech signal is matched...

  6. Development of a composite repair system for reinforcing offshore risers

    E-Print Network [OSTI]

    Alexander, Christopher Richard

    2009-05-15T23:59:59.000Z

    A research program was conducted to investigate the application of composite materials in repairing corroded offshore risers, leading to the development of an optimized repair using a hybrid carbon/E-glass system. The objective of this research...

  7. Auto-Concealment of Supersymmetry in Extra Dimensions

    E-Print Network [OSTI]

    Savas Dimopoulos; Kiel Howe; John March-Russell; James Scoville

    2014-12-02T23:59:59.000Z

    In supersymmetric (SUSY) theories with extra dimensions the visible energy in sparticle decays can be significantly reduced and its energy distribution broadened, thus significantly weakening the present collider limits on SUSY. The mechanism applies when the lightest supersymmetric particle (LSP) is a bulk state-- e.g. a bulk modulino, axino, or gravitino-- the size of the extra dimensions larger than ~$10^{-14}$ cm, and for a broad variety of visible sparticle spectra. In such cases the lightest ordinary supersymmetric particle (LOSP), necessarily a brane-localised state, decays to the Kaluza-Klein (KK) discretuum of the LSP. This dynamically realises the compression mechanism for hiding SUSY as decays into the more numerous heavier KK LSP states are favored. We find LHC limits on right-handed slepton LOSPs evaporate, while LHC limits on stop LOSPs weaken to ~350-410 GeV compared to ~700 GeV for a stop decaying to a massless LSP. Similarly, for the searches we consider, present limits on direct production of degenerate first and second generation squarks drop to ~450 GeV compared to ~800 GeV for a squark decaying to a massless LSP. Auto-concealment typically works for a fundamental gravitational scale of $M_*$~10-100 TeV, a scale sufficiently high that traditional searches for signatures of extra dimensions are mostly avoided. If superpartners are discovered, their prompt, displaced, or stopped decays can also provide new search opportunities for extra dimensions with the potential to reach $M_*$~$10^9$ GeV. This mechanism applies more generally than just SUSY theories, pertaining to any theory where there is a discrete quantum number shared by both brane and bulk sectors.

  8. Repairing Type Errors in Functional Programs 

    E-Print Network [OSTI]

    McAdam, Bruce J

    Type systems for programming languages can be used by compilers to reject programs which are found to be unsound and which may, therefore, fail to execute successfully. When a program is rejected the programmer must repair it so that it can be type...

  9. An emergency response team for membrane repair

    E-Print Network [OSTI]

    Kirchhausen, Tomas

    events, which we focus on here. As discussed later, Ca2+ influx at the site of plasma membrane-fusion events are required to repair a torn plasma membrane, and we propose that this emergency products and the plasma membrane. Reseal or die. Plasma-membrane disruption is a normal event in the life

  10. EPA Lead Safety for Renovation, Repair and

    E-Print Network [OSTI]

    Tennessee, University of

    EPA Lead Safety for Renovation, Repair and Painting (RRP) Course Certified Renovators Class, CSP, CHMM, Certified Lead Paint Inspector.; Certified Renovator; EPA Ac- credited Lead RRP trainer or fax registratio Registration Form Cash Method of Payment Check Name Mailing Address Phone Lead Safety

  11. Visualization of Mismatch Repair in Bacterial Cells

    E-Print Network [OSTI]

    Smith, Bradley T.

    We determined the localizations of mismatch repair proteins in living Bacillus subtilis cells. MutS-GFP colocalized with the chromosome in all cells and formed foci in a subset of cells. MutL-GFP formed foci in a subset ...

  12. Regulation of DNA repair by parkin

    SciTech Connect (OSTI)

    Kao, Shyan-Yuan, E-mail: shyan-yuan_kao@meei.harvard.edu [Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114 (United States)] [Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114 (United States)

    2009-05-01T23:59:59.000Z

    Mutation of parkin is one of the most prevalent causes of autosomal recessive Parkinson's disease (PD). Parkin is an E3 ubiquitin ligase that acts on a variety of substrates, resulting in polyubiquitination and degradation by the proteasome or monoubiquitination and regulation of biological activity. However, the cellular functions of parkin that relate to its pathological involvement in PD are not well understood. Here we show that parkin is essential for optimal repair of DNA damage. Parkin-deficient cells exhibit reduced DNA excision repair that can be restored by transfection of wild-type parkin, but not by transfection of a pathological parkin mutant. Parkin also protects against DNA damage-induced cell death, an activity that is largely lost in the pathological mutant. Moreover, parkin interacts with the proliferating cell nuclear antigen (PCNA), a protein that coordinates DNA excision repair. These results suggest that parkin promotes DNA repair and protects against genotoxicity, and implicate DNA damage as a potential pathogenic mechanism in PD.

  13. Antibody specific for a DNA repair protein

    DOE Patents [OSTI]

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-07-11T23:59:59.000Z

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  14. DNA encoding a DNA repair protein

    DOE Patents [OSTI]

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-08-15T23:59:59.000Z

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  15. Method for mask repair using defect compensation

    DOE Patents [OSTI]

    Sweeney, Donald W. (San Ramon, CA); Ray-Chaudhuri, Avijit K. (Livermore, CA)

    2001-01-01T23:59:59.000Z

    A method for repair of amplitude and/or phase defects in lithographic masks. The method involves modifying or altering a portion of the absorber pattern on the surface of the mask blank proximate to the mask defect to compensate for the local disturbance (amplitude or phase) of the optical field due to the defect.

  16. Laboratory testing of closure cap repair techniques

    SciTech Connect (OSTI)

    Persoff, P.; Moridis, G. [Lawrence Berkeley National Lab., CA (United States); Tuck, D.M. [Westinghouse Savannah River Company, Aiken, SC (United States)] [and others

    1996-10-01T23:59:59.000Z

    Landfill design requires a low permeability closure cap as well as a low permeability liner. The Savannah River Site, in South Carolina, has approximately 85 acres of mixed waste landfills covered with compacted kaolin clay. Maintaining low permeability of the clay cap requires both that the permeability of the compacted clay itself remain low and that the integrity of the barrier be maintained. Barrier breaches typically result from penetration by roots or animals, and especially cracks caused by uneven settling or desiccation. In this study, clay layers, 0.81 m in diameter and 7.6 cm thick, were compacted in 7 lysimeters to simulate closure caps. The hydraulic conductivity of each layer was measured, and the compacted clay layers (CCL`s) were cracked by drying. Then various repair techniques were applied and the effectiveness of each repair was assessed by remeasuring the hydraulic conductivity. Finally the repaired CCL was again dried and measured to determine how the repair responded to the conditions that caused the original failure. For a full report of this investigation see Persoff et al. Six repair techniques have been tested, four of which involve the use of injectable barrier liquids colloidal silica (CS) and polysiloxane (PSX) described below: (I) covering the crack with a bentonite geosynthetic clay liner (GCL), (ii) recompaction of new kaolinite at STD+3 moisture content joined to existing kaolinite that had dried and shrunk, (iii) direct injection of colloidal silica to a crack, (iv) injection of colloidal silica (CS) to wells in an overlying sand layer, (v) direct injection of polysiloxane to a crack, and (vi), injection of polysiloxane (PSX) to wells in an overlying soil layer.

  17. Helium bubble distributions in reactor tank repair specimens

    SciTech Connect (OSTI)

    Tosten, M.H.; Kestin, P.A.

    1992-03-01T23:59:59.000Z

    This report discusses the Reactor Tank Repair (RTR) program was initiated to develop an in-tank repair process capable of repairing stress corrosion cracks within the SRS reactor tank walls, in the event that such a repair is needed. Previous attempts to repair C-reactor tank with a gas tungsten arc (GTA) welding process were unsuccessful due to significant cracking that occurred in the heat-affected-zones adjacent to the repair welds. It was determined that this additional cracking was a result of helium embrittlement caused by the combined effects of helium (existing within the tank walls), the high heat input associated with the GTA process, and weld shrinkage stresses. Based on the results of earlier studies it was suggested that the effects of helium embrittlement could be minimized by using a low heat input GMA process. Metallographic analysis played an important role throughout the investigation of alternative welding methods for the repair of helium-containing materials.

  18. Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard

    SciTech Connect (OSTI)

    Terwilliger, Thomas C., E-mail: terwilliger@lanl.gov [Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545 (United States); Grosse-Kunstleve, Ralf W.; Afonine, Pavel V.; Moriarty, Nigel W.; Zwart, Peter H. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720 (United States); Hung, Li-Wei [Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545 (United States); Read, Randy J. [Department of Haematology, University of Cambridge, Cambridge CB2 0XY (United Kingdom); Adams, Paul D., E-mail: terwilliger@lanl.gov [Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720 (United States); Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545 (United States)

    2008-01-01T23:59:59.000Z

    The highly automated PHENIX AutoBuild wizard is described. The procedure can be applied equally well to phases derived from isomorphous/anomalous and molecular-replacement methods. The PHENIX AutoBuild wizard is a highly automated tool for iterative model building, structure refinement and density modification using RESOLVE model building, RESOLVE statistical density modification and phenix.refine structure refinement. Recent advances in the AutoBuild wizard and phenix.refine include automated detection and application of NCS from models as they are built, extensive model-completion algorithms and automated solvent-molecule picking. Model-completion algorithms in the AutoBuild wizard include loop building, crossovers between chains in different models of a structure and side-chain optimization. The AutoBuild wizard has been applied to a set of 48 structures at resolutions ranging from 1.1 to 3.2 Å, resulting in a mean R factor of 0.24 and a mean free R factor of 0.29. The R factor of the final model is dependent on the quality of the starting electron density and is relatively independent of resolution.

  19. Environmental assessment for the Plating Shop Replacement, Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect (OSTI)

    Not Available

    1992-03-01T23:59:59.000Z

    The existing of Y-12 Plant Plating Shop provides vital support functions for the US Department of Energy (DOE) Defense Programs operations. In addition to weapon component plating, the facility performs other plating services to support existing operations for the Y-12 Plant, other DOE facilities, and other federal agencies. In addition, the facility would also provide essential deplating services for weapons reclamation and teardown. The existing Y-12 Plant Plating Shop is presently located in a structure which is rapidly deteriorating and obsolete. The existing building structure was originally designed to house a steam plant, not chemical plating operations. As such, vapors from plating operations have deteriorated the structure to a point where a new facility is needed for continued safe operations. The potential environmental impacts of the proposed action was anticipated to be minimal and would affect no environmentally sensitive areas. Some short-term construction- and demolition-related effects would occur in an already highly industrialized setting. These include temporarily disturbing 72,000 square feet of land for the new plating shop and related site preparation activities, constructing a permanent building on part of the area, and using 80 construction personnel over a period of 18 months for site preparation and construction. Demolition effects vary depending on the environmentally suitable option selected, but they could involve as much as 262 cubic yards of concrete rubble and approximately 1600 cubic yards of soil disposed as waste. Either 1600 cubic yards of fresh soil or 1850 yards of clay and fresh soil could be required. Soil erosion would be minimal. Approximately 20 construction personnel would be involved for 12 months in demolition activities.

  20. Selective batch crushing in the coal-preparation shop at OAO NTMK

    SciTech Connect (OSTI)

    N.A. Berkutov; Yu.V. Stepanov; P.V. Shtark; L.A. Makhortova; N.K. Popova; D.A. Koshkarov; N.V. Tsarev [OAO Nizhnetagil'skii Metallurgicheskii Kombinat (NTMK)(Russian Federation)

    2007-05-15T23:59:59.000Z

    In September 2004, after reconstruction at OAO Nizhnetagil'skii Metallurgicheskii Kombinat (NTMK), blast furnace 6 went into operation for the production of vanadium from hot metal. At the startup of furnace 6, besides optimising its composition; it was decided to restore selective crushing of the coal batch using pneumatic and mechanical separation in the third unit of the coal preparation shop. Additional increase in the mechanical strength of coke by 1.5-2.0% was predicted with a 0.5-1.0% decrease in wear.

  1. KINETIC MODELING OF A SURROGATE DIESEL FUEL APPLIED TO 3D AUTO-IGNITION IN HCCI ENGINES

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    KINETIC MODELING OF A SURROGATE DIESEL FUEL APPLIED TO 3D AUTO-IGNITION IN HCCI ENGINES R OF A SURROGATE DIESEL FUEL APPLIED TO 3D AUTO-IGNITION IN HCCI ENGINES INTRODUCTION Engines running on HCCI combustion mode (Homogeneous Charge Compression Ignition) have the potential to provide both diesel

  2. De los orgenes en el auto de Caldern La lepra de Constantino (1647-1657?)

    E-Print Network [OSTI]

    Boyer, Edmond

    . Galván y R. Arana Caballero (eds.), «Introducción» a La lepra de Constantino, Pamplona. Arana Caballero, «La lepra de Constantino: análisis métrico de un auto calderoniano en relación con el of Calderon`s La lepra de Constantino», Hispanic Review, 9, 1941, p. 482-488, y Galván y Arana Caballero, 2008

  3. auto-responsive honeypot architecture: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    auto-responsive honeypot architecture First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Detecting...

  4. M:\\Security Reinstatement Procedures (Auto Lockout).sjm.09132011 HR Security Access Reinstatement

    E-Print Network [OSTI]

    Adali, Tulay

    M:\\Security Reinstatement Procedures (Auto Lockout).sjm.09132011 HR Security Access Reinstatement Profile section, indicate "restore access prior to lockout". Leave the bottom section (adding and removing authority sign the form for approval. 2. Print the lock-out email notification received from DoIT and attach

  5. M:\\Security Reinstatement Procedures (Auto Lockout).sjm.09132011 HR Security Access Reinstatement

    E-Print Network [OSTI]

    Adali, Tulay

    M:\\Security Reinstatement Procedures (Auto Lockout).sjm.09132011 HR Security Access Reinstatement section, indicate "restore access prior to lockout". Leave the bottom section (adding and removing roles sign the form for approval. 2. Print the lock-out email notification received from DoIT and attach

  6. A spatiotemporal auto-regressive moving average model for solar radiation

    E-Print Network [OSTI]

    Stone, J. V.

    A spatiotemporal auto-regressive moving average model for solar radiation C.A. Glasbey and D 1). Solar radiation, averaged over ten minute intervals, was recorded at each site for two years otherwise there are too many parameters to be estimated. As we wish to simulate solar radiation on a network

  7. ScalaBenchGen: Auto-Generation of Communication Benchmarks Traces Department of Computer Science

    E-Print Network [OSTI]

    Mueller, Frank

    ScalaBenchGen: Auto-Generation of Communication Benchmarks Traces Xing Wu Department of Computer@cs.ncsu.edu Abstract--Benchmarks are essential for evaluating HPC hardware and software for petascale machines and beyond. But benchmark creation is a tedious manual process. As a result, benchmarks tend to lag behind

  8. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William

    2013-03-19T23:59:59.000Z

    A method for promoting and suppressing auto-induction of transcription of a cloned gene 1 of bacteriophage T7 in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells.

  9. Iterative model-building, structure refinement, and density modification with the PHENIX AutoBuild Wizard

    SciTech Connect (OSTI)

    Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545, USA; Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720, USA; Department of Haematology, University of Cambridge, Cambridge CB2 0XY, England; Terwilliger, Thomas; Terwilliger, T.C.; Grosse-Kunstleve, Ralf Wilhelm; Afonine, P.V.; Moriarty, N.W.; Zwart, P.H.; Hung, L.-W.; Read, R.J.; Adams, P.D.

    2007-04-29T23:59:59.000Z

    The PHENIX AutoBuild Wizard is a highly automated tool for iterative model-building, structure refinement and density modification using RESOLVE or TEXTAL model-building, RESOLVE statistical density modification, and phenix.refine structure refinement. Recent advances in the AutoBuild Wizard and phenix.refine include automated detection and application of NCS from models as they are built, extensive model completion algorithms, and automated solvent molecule picking. Model completion algorithms in the AutoBuild Wizard include loop-building, crossovers between chains in different models of a structure, and side-chain optimization. The AutoBuild Wizard has been applied to a set of 48 structures at resolutions ranging from 1.1 {angstrom} to 3.2 {angstrom}, resulting in a mean R-factor of 0.24 and a mean free R factor of 0.29. The R-factor of the final model is dependent on the quality of the starting electron density, and relatively independent of resolution.

  10. Flamelet-based modeling of auto-ignition with thermal inhomogeneities for application

    E-Print Network [OSTI]

    Pitsch, Heinz

    Flamelet-based modeling of auto-ignition with thermal inhomogeneities for application to HCCI National Laboratories, Livermore, CA 94551, USA Abstract Homogeneous-charge compression ignition (HCCI ignition engines. However, HCCI engines expe- rience very large heat release rates which can cause too

  11. EFFECTS OF MIXTURE INHOMOGENEITY ON THE AUTO-IGNITION OF REACTANTS UNDER HCCI ENVIRONMENT

    E-Print Network [OSTI]

    Im, Hong G.

    EFFECTS OF MIXTURE INHOMOGENEITY ON THE AUTO-IGNITION OF REACTANTS UNDER HCCI ENVIRONMENT Ramanan ABSTRACT As an attempt at providing insight to develop bet- ter modeling strategies for HCCI engines in multi-dimensional simulation of HCCI engines. INTRODUCTION The homogenous charge compression ignition

  12. Model-driven Configuration of Cloud Computing Auto-scaling Infrastructure

    E-Print Network [OSTI]

    Schmidt, Douglas C.

    Model-driven Configuration of Cloud Computing Auto-scaling Infrastructure Brian Dougherty1 and Jules White2 and Douglas C. Schmidt1 1 Vanderbilt University briand,schmidt@dre.vanderbilt.edu 2 Virginia Tech julesw@vt.edu Abstract. Cloud computing uses virtualized computational resources to allow

  13. Modeling of NO sensitization of IC engines surrogate fuels auto-ignition and combustion

    E-Print Network [OSTI]

    Anderlohr, Jörg; Bounaceur, Roda; Battin-Leclerc, Frédérique

    2009-01-01T23:59:59.000Z

    This paper presents a new chemical kinetic model developed for the simulation of auto-ignition and combustion of engine surrogate fuel mixtures sensitized by the presence of NOx. The chemical mechanism is based on the PRF auto-ignition model (n-heptane/iso-octane) of Buda et al. [1] and the NO/n-butane/n-pentane model of Glaude et al. [2]. The later mechanism has been taken as a reference for the reactions of NOx with larger alcanes (n-heptane, iso-octane). A coherent two components engine fuel surrogate mechanism has been generated which accounts for the influence of NOx on auto-ignition. The mechanism has been validated for temperatures between 700 K and 1100 K and pressures between 1 and 10 atm covering the temperature and pressure ranges characteristic of engine post-oxidation thermodynamic conditions. Experiments used for validation include jet stirred reactor conditions for species evolution as a function of temperature, as well as diesel HCCI engine experiments for auto-ignition delay time measurements...

  14. Incremental Development for Automotive Software in AutoMoDe Andreas Bauer1

    E-Print Network [OSTI]

    Braun, Peter

    Incremental Development for Automotive Software in AutoMoDe Andreas Bauer1 Jan Romberg1 Bernhard Validas AG 3 ETAS GmbH 4 PMSF IT Consulting 5 Robert Bosch GmbH Abstract Automotive software development. To facilitate the design and evolution of heterogeneous automotive software, suitable views for each level

  15. A description of auto-fixed subgroups in a free A. Martino a

    E-Print Network [OSTI]

    Ventura, Enric

    A description of auto-fixed subgroups in a free group A. Martino a , E. Ventura b aDept. of Math(F)/Inn(F) is the outer Email addresses: AMartino@crm.es (A. Martino), enric.ventura@upc.es (E. Ventura). Preprint

  16. NO NAME:Accident reporting and Auto Insurance.doc July 15, 2014

    E-Print Network [OSTI]

    Kelly, Scott David

    NO NAME:Accident reporting and Auto Insurance.doc July 15, 2014 STATEMENT OF RESOURCES TO ADDRESS CLAIMS ARISING FROM ACCIDENTS INVOLVING VEHICLES OPERATED ON UNIVERSITY BUSINESS This statement contains a general description of resources available in connection with claims arising from accidents involving

  17. FuelEff&PhysicsAutosSanders FUEL EFFICIENCY AND THE PHYSICS OF AUTOMOBILES1

    E-Print Network [OSTI]

    Edwards, Paul N.

    FuelEff&PhysicsAutosSanders 1 FUEL EFFICIENCY AND THE PHYSICS OF AUTOMOBILES1 Marc Ross, Physics in the operation of a modern automobile are expressed in terms of simple algebraic approximations. One purpose-engine thermodynamic efficiency, and engine and transmission frictions. The analysis applies to today's automobiles

  18. DNA repair is the target of novel antibiotics

    E-Print Network [OSTI]

    Gunderson, Carl Wayne

    2007-01-01T23:59:59.000Z

    W. & A. M. Segall, (2006) DNA repair, a novel antibacterialjunction-trapping peptides induce DNA damage and chromosomePeptide inhibitors of DNA cleavage by tyrosine recombinases

  19. Motor Repair Tech Brief | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreaking ofOil &315_ArnibanPriorityof EnergyDepartmentRepair Tech Brief Motor

  20. Window shopping

    SciTech Connect (OSTI)

    Best, D.

    1990-03-01T23:59:59.000Z

    The author addresses the energy efficiency of windows and describes changes and new products available in this consumer information article. Experiments currently being done by Lawrence Berkeley Laboratory (LBL), Bonneville Power Authority and the Washington State Energy Office show that some of these superwindows collect more energy from the sun than they let escape from inside the home. One type of window in current production is the low-E (low-emissivity) and the IGUs (insulated glass units). Low-E techniques include glazing of the glass with various materials including polyester and metallic coatings. Other measures include filling the airspace in double pane windows with argon, aerogel or by creating a vacuum in the airspace. Another factor the author considers is ultraviolet light protection.

  1. Role of Tissue Repair in Survival from S-(1,2-Dichlorovinyl)-L-Cysteine– Induced Acute Renal Tubular Necrosis in the Mouse

    E-Print Network [OSTI]

    unknown authors

    2003-01-01T23:59:59.000Z

    S-(1,2-Dichlorovinyl)-L-cysteine (DCVC), a model nephrotoxi-cant in mice, causes acute tubular necrosis and death at high doses. Our earlier studies revealed that renal tissue repair was critical for survival in mice with DCVC nephrotoxicity. The ob-jective of this study was to investigate if increasing renal tissue repair could protect mice from the lethal outcome of DCVC. Male Swiss Webster (SW) mice were administered a low dose of DCVC (15 mg/kg, ip) 72 h before injection of a normally lethal dose of DCVC (75 mg/kg, ip); this resulted in 100 % protection against the lethal effect of DCVC. Because DCVC caused twofold decrease in cytosolic and mitochondrial -lyase activity, the possibility that DCVC protection may be caused by decreased bioactivation was examined. Mercuric chloride (HgCl2, 6 mg/kg), a nephrotoxicant with no effect on -lyase activity, was administered 96 h before a lethal dose of DCVC. This also resulted in 100 % protection from the lethal effect of DCVC. In both studies total glutathione was unchanged at any time after the lethal dose of DCVC was admin-istered, obviating the role of glutathione in protection. In both cases the augmented and sustained tissue repair induced by prim-ing dose and documented by 3H-thymidine pulse labeling and immunocytochemistry for proliferating cell nuclear antigen re-sulted in 100 % survival in spite of the extensive renal injury. These findings suggest that stimulation of renal tubular repair by the priming dose, through augmented cell division, and the resistance of new cells to mechanisms of progression of injury, underlies auto- and heteroprotection against DCVC. The molecular mech-anisms may have potential application in pharmacotherapeutic intervention for treatment of acute renal failure.

  2. Remote foods shopping robot system in a supermarket Tetsuo TOMIZAWA, National Inst. of Advanced Industrial Science and Technology

    E-Print Network [OSTI]

    Ohya, Akihisa

    Remote foods shopping robot system in a supermarket Tetsuo TOMIZAWA, National Inst as a teleoperated tool for accessing and manipulating remote objects. This system attempts to answer the challenge in this research is to help people buy fresh food in a supermarket from a remote location using the Internet. We

  3. NCDC the "One Stop Shop" for all WSR-88D Level II Data Services Stephen A. Del Greco*

    E-Print Network [OSTI]

    Droegemeier, Kelvin K.

    II radar inventories, data, and visualization software are available, at no cost to the user, viaNCDC the "One Stop Shop" for all WSR-88D Level II Data Services Stephen A. Del Greco* * National Climatic Data Center - Data Operations Division, Asheville NC 28801 Phone (828) 271-4281, Fax (828) 271

  4. Coherent testing and simulation of composite blade repair

    E-Print Network [OSTI]

    McNichols, Brian Glenn

    1997-01-01T23:59:59.000Z

    The objective of this research program is to experimentally and computationally determine the static and fatigue response for two methods of repair to an E/Glass-Epoxy sandwich laminate. The proposed methods of repair are a scarf and overlap patch...

  5. Computational model of aortic valve surgical repair using grafted pericardium

    E-Print Network [OSTI]

    1 Computational model of aortic valve surgical repair using grafted pericardium Peter E. Hammer1, aortic valve repair, membrane, surgical planning, leaflet graft, pericardium ABSTRACT Aortic valve leaflets. Difficulty is largely due to the complex geometry and function of the valve and the lower

  6. Kinetic modelling of a surrogate diesel fuel applied to 3D auto-ignition in HCCI engines

    E-Print Network [OSTI]

    Bounaceur, Roda; Fournet, René; Battin-Leclerc, Frédérique; Jay, S; Da Cruz, A Pires

    2007-01-01T23:59:59.000Z

    The prediction of auto-ignition delay times in HCCI engines has risen interest on detailed chemical models. This paper described a validated kinetic mechanism for the oxidation of a model Diesel fuel (n-decane and ?-methylnaphthalene). The 3D model for the description of low and high temperature auto-ignition in engines is presented. The behavior of the model fuel is compared with that of n-heptane. Simulations show that the 3D model coupled with the kinetic mechanism can reproduce experimental HCCI and Diesel engine results and that the correct modeling of auto-ignition in the cool flame region is essential in HCCI conditions.

  7. Type C investigation of electrical fabrication projects in ICF Kaiser shops

    SciTech Connect (OSTI)

    Huckfeldt, R.A.

    1995-06-01T23:59:59.000Z

    A Type C Investigation Board was convened to investigate an electrical miswiring problem found during the operation of the electrical distribution trailer for the TWRS Rotary Mode Core Sampling Truck {number_sign}2. The trailer was designed by WHC and fabricated ICF KH on site for use in the Characterization Program. This problem resulted in a serious safety hazard since the support truck frame/chassis became electrically energized. This final report provides results of the ``Type C Investigation, Electrical Fabrication Projects in ICF KH Shops, June, 1995.`` It contains the investigation scope, executive summary, relevant facts, analysis, conclusions and corrective actions. DOE Order 5484.1, ``Environmental Protection, Safety and Health Protection Information Reporting Requirements,`` was followed in preparation of this report. Because the incident was electrical in nature and involved both Westinghouse Hanford Company and ICF Kaiser Hanford organizations, the board included members from both contractors and members with considerable electrical expertise.

  8. Engineering Evaluation/Cost Analysis (EE/CA) for Decommissioning of TAN-607 Hot Shop Area

    SciTech Connect (OSTI)

    J. P. Floerke

    2007-02-05T23:59:59.000Z

    Test Area North (TAN) -607, the Technical Support Facility, is located at the north end of the Idaho National Laboratory (INL) Site. U.S. Department of Energy Idaho Operations Office (DOE-ID) is proposing to decommission the northern section of the TAN-607 facility, hereinafter referred to as TAN-607 Hot Shop Area, under a Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) non-time-critical removal action (NTCRA). Despite significant efforts by the United States (U.S.) Department of Energy (DOE) to secure new business, no future mission has been identified for the TAN-607 Hot Shop Area. Its disposition has been agreed to by the Idaho State Historical Preservation Office documented in the Memorandum of Agreement signed October 2005 and it is therefore considered a surplus facility. A key element in DOE's strategy for surplus facilities is decommissioning to the maximum extent possible to ensure risk and building footprint reduction and thereby eliminating operations and maintenance cost. In addition, the DOE's 2006 Strategic Plan is ''complete cleanup of the contaminated nuclear weapons manufacturing and testing sites across the United States. DOE is responsible for the risk reduction and cleanup of the environmental legacy of the Nation's nuclear weapons program, one of the largest, most diverse, and technically complex environmental programs in the world. The Department will successfully achieve this strategic goal by ensuring the safety of the DOE employees and U.S. citizens, acquiring the best resources to complete the complex tasks, and managing projects throughout the United States in the most efficient and effective manner.'' TAN-607 is designated as a historical Signature Property by DOE Headquarters Advisory Council on Historic Preservation and, as such, public participation is required to determine the final disposition of the facility. The decommissioning action will place the TAN-607 Hot Shop Area in a final configuration that will be protective of human health and the environment. Decommissioning the TAN-607 Hot Shop Area is consistent with the joint DOE and U.S. Environmental Protection Agency (EPA) Policy on Decommissioning of Department of Energy Facilities Under the Comprehensive Environmental Response, Compensation and Liability Act, which establishes the CERCLA NTCRA process as the preferred approach for decommissioning surplus DOE facilities. Under this policy, a NTCRA may be taken when DOE determines that the action will prevent, minimize, stabilize, or eliminate a risk to human health and/or the environment. When DOE determines that a CERCLA NTCRA is necessary, DOE is authorized to evaluate, select, and implement the removal action that DOE determines is most appropriate to address the potential risk posed by the release or threat of release. This action is taken in accordance with applicable authorities and in conjunction with EPA and the State of Idaho pursuant to Section 5.3 of the Federal Facility Agreement and Consent Order. In keeping with the joint policy, this engineering evaluation/cost analysis (EE/CA) was developed in accordance with CERCLA as amended by the ''Superfund Amendments and Reauthorization Act of 1986'' and in accordance with the ''National Oil and Hazardous Substances Pollution Contingency Plan.'' This EE/CA is consistent with the remedial action objectives (RAOs) of the Final Record of Decision, Test Area North, Operable Unit 1-10 and supports the overall remediation goals established through the Federal Facility Agreement and Consent Order for Waste Area Group 1. Waste Area Group 1 is located at TAN.

  9. Stencil Computation Optimization and Auto-tuning on State-of-the-Art Multicore Architectures

    SciTech Connect (OSTI)

    Datta, Kaushik; Murphy, Mark; Volkov, Vasily; Williams, Samuel; Carter, Jonathan; Oliker, Leonid; Patterson, David; Shalf, John; Yelick, Katherine

    2008-08-22T23:59:59.000Z

    Understanding the most efficient design and utilization of emerging multicore systems is one of the most challenging questions faced by the mainstream and scientific computing industries in several decades. Our work explores multicore stencil (nearest-neighbor) computations -- a class of algorithms at the heart of many structured grid codes, including PDE solvers. We develop a number of effective optimization strategies, and build an auto-tuning environment that searches over our optimizations and their parameters to minimize runtime, while maximizing performance portability. To evaluate the effectiveness of these strategies we explore the broadest set of multicore architectures in the current HPC literature, including the Intel Clovertown, AMD Barcelona, Sun Victoria Falls, IBM QS22 PowerXCell 8i, and NVIDIA GTX280. Overall, our auto-tuning optimization methodology results in the fastest multicore stencil performance to date. Finally, we present several key insights into the architectural trade-offs of emerging multicore designs and their implications on scientific algorithm development.

  10. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William (Stony Brook, NY)

    2010-07-20T23:59:59.000Z

    A bacterial growth medium for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a lac repressor. Also disclosed is a bacterial growth medium for improving the production of a selenomethionine-containing protein or polypeptide in a bacterial cell, the protein or polypeptide being produced by recombinant DNA techniques from a lac or T7lac promoter, the bacterial cell encoding a vitamin B12-dependent homocysteine methylase. Finally, disclosed is a bacterial growth medium for suppressing auto-induction of expression in cultures of bacterial cells grown batchwise, said transcription being under the control of lac repressor.

  11. Using instrument scraper surveys for corrosion repair

    SciTech Connect (OSTI)

    Akhnoukh, S.R.; Baghabrah, M.A. (Aramco (SA))

    1990-07-01T23:59:59.000Z

    This paper reports on a program for overall pipe line repair. This program was implemented to maintain pipe line integrity and for identifying problem areas which require reconditioning or replacing by: reviewing pipe line leak history; checking periodically lifetime expectancy and integrity of pipe coatings; using cathodic protection annual survey results to locate low potential areas (close-interval survey is needed to identify the exact location of corrosion); and hydrotesting the pipe line (using leaks or ruptures from the hydrotest to identify problem areas). The pipe line revalidation plan is insufficient for identifying pipe line leaks. Instrumented pig testing provides more accurate and reliable ways of testing the pipe line for internal or external corrosion or defects.

  12. A Goal-driven Auto-Configuration Tool for the Distributed Workflow Management System Mentor-lite

    E-Print Network [OSTI]

    1 A Goal-driven Auto-Configuration Tool for the Distributed Workflow Management System Mentor,weissenfels,shegalov,wonner,weikum}@cs.uni-sb.de WWW: http://www-dbs.cs.uni-sb.de/ Abstract The Mentor-lite prototype has been developed within of Mentor-lite and elaborate on a goal-driven auto- configuration tool for Mentor-lite and similar workflow

  13. A study of the information needs of the current end-user of the Texas Auto Visitor Survey report 

    E-Print Network [OSTI]

    Deater, Lois Ann

    1992-01-01T23:59:59.000Z

    Record of Study A STUDY OF THE INFORMATION NEEDS OF THE CURRENT END-USER OF THE TEXAS AUTO VISITOR SURVEY REPORT A PROFESSIONAL PAPER by LOIS ANN DEATER Submitted to the College of Agriculture and Life Scrences of Texas AlzM University... in partial fulfillment of the requrrements for the degree of MASTER OF AGRICULTURE December 1992 Recreation, Park & Tourism Sciences Recreation and Resources Development A SIUDY OF THE INFORMATION NEEDS OF THE CURRENT END-USER OF THE TEXAS AUTO...

  14. Effect of polarization and focusing on laser pulse driven auto-resonant particle acceleration

    SciTech Connect (OSTI)

    Sagar, Vikram; Sengupta, Sudip; Kaw, Predhiman [Institute for Plasma Research, Bhat, Gandhinagar-382428 (India)] [Institute for Plasma Research, Bhat, Gandhinagar-382428 (India)

    2014-04-15T23:59:59.000Z

    The effect of laser polarization and focusing is theoretically studied on the final energy gain of a particle in the Auto-resonant acceleration scheme using a finite duration laser pulse with Gaussian shaped temporal envelope. The exact expressions for dynamical variables viz. position, momentum, and energy are obtained by analytically solving the relativistic equation of motion describing particle dynamics in the combined field of an elliptically polarized finite duration pulse and homogeneous static axial magnetic field. From the solutions, it is shown that for a given set of laser parameters viz. intensity and pulse length along with static magnetic field, the energy gain by a positively charged particle is maximum for a right circularly polarized laser pulse. Further, a new scheme is proposed for particle acceleration by subjecting it to the combined field of a focused finite duration laser pulse and static axial magnetic field. In this scheme, the particle is initially accelerated by the focused laser field, which drives the non-resonant particle to second stage of acceleration by cyclotron Auto-resonance. The new scheme is found to be efficient over two individual schemes, i.e., auto-resonant acceleration and direct acceleration by focused laser field, as significant particle acceleration can be achieved at one order lesser values of static axial magnetic field and laser intensity.

  15. Lagged Poincar\\'{e} and auto-correlation analysis of Heart rate variability in diabetes

    E-Print Network [OSTI]

    Ghatak, S K

    2010-01-01T23:59:59.000Z

    The heart rate variability (HRV) in diabetic human subjects, has been analyzed using lagged Poincar\\'{e} plot, auto-correlation and the detrended fluctuation analysis methods. The parameters $SD1$, and $SD12 (= SD1/SD2)$ for Poincar\\'{e} plot for diabetic are lower than that for non-diabetic subjects and reverse is case for $SD2$ for all lagged number (m). The slope and the curvature of the plot SD12 vs m is much reduced for diabetic subject. The scatter plot of two successive interbeat intervals points out smaller variability in diabetic heart. The detrended fluctuation exponent has a higher value for diabetic group. The auto-correlation function of the deviation of interbeat interval in diabetic group shows highly correlated pattern when compared to that of normal one. The study suggests that the curvature of $SD12$ and auto-correlation method appear to be better way to assess the alteration of regulatory system on heart dynamics in diabetic condition.

  16. A tissue engineering strategy for integrative cartilage repair

    E-Print Network [OSTI]

    Mroszczyk, Keri A

    2014-01-01T23:59:59.000Z

    Tissue engineering for cartilage repair is a promising approach for improving the healing of articular defects, as biomaterials and growth factors can be supplied directly to a focal lesion. However, integrating neo-tissue ...

  17. Optimizing chondrogenic factors and protein delivery methods for cartilage repair

    E-Print Network [OSTI]

    Florine, Emily Marie

    2012-01-01T23:59:59.000Z

    Joint injuries are common and often result in damage to cartilage, which has a limited ability to repair itself. Tissue engineering is a promising approach for improving cartilage healing in which biomaterials and chemical ...

  18. Availability Analysis of Repairable Computer Systems and Stationarity Detection

    E-Print Network [OSTI]

    Sericola, Bruno

    Availability Analysis of Repairable Computer Systems and Stationarity Detection Bruno Sericola AbstractÐPoint availability and expected interval availability are dependability measures respectively in this paper a new algorithm to compute these two availability measures. This algorithm is based

  19. Intermediate hearth repair technique at Thyssen Stahl AG

    SciTech Connect (OSTI)

    Kowalski, W.; Bachhofen, H.J.; Ruether, P.; Ballewski, T. [Thyssen Stahl AG, Duisburg (Germany)

    1996-12-31T23:59:59.000Z

    Nowadays various techniques for the fastest possible intermediate repair and/or emplacement of refractory materials above the tuyere level allow a significant extension of furnace campaign life. The latter are hence now exclusively determined by the service life of the hearth. The improvement of hearth monitoring and the estimation of residual brick strength of the refractory lining on the basis of temperature measurements in the hearth enable the location of individual zones of premature wear. These measurement methods, which were developed by Thyssen Stahl AG, aid the decision to undertake selective repair of the hearth. Three areas of repair are differentiated: taphole zone; hearth wall, localized; and hearth wall, extensive. This hearth repair method is described in this report using the example of hearth refurbishing blast furnace 8, Hamborn.

  20. Repair Sequences in American Learners of German Interlanguage

    E-Print Network [OSTI]

    Wisbey, Evelyn

    2010-04-25T23:59:59.000Z

    This study in Conversation Analysis investigates the organization of other-initiated repair sequences in American learners of German, i.e., it examines how learners deal with troubles in hearing or understanding that they ...

  1. To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sent: Monday, January 29, 2007 6:28 PM To: Mansueti, Lawrence Subject: RE: Pepco Scheduled Line Repair Dec. 1-20, 2006 Larry, Regarding the planned line outage,...

  2. Characterization and reclamation assessment for the Central Shops Diesel Storage Facility, Savannah River Site, Aiken, South Carolina

    SciTech Connect (OSTI)

    Fliermans, C.B.; Hazen, T.C.; Bledsoe, H.

    1993-10-01T23:59:59.000Z

    The contamination of subsurface terrestrial environments by organic contaminants is a global phenomenon. The remediation of such environments requires innovative assessment techniques and strategies for successful clean-ups. Central Shops Diesel Storage Facility at Savannah River Site was characterized to determine the extent of subsurface diesel fuel contamination using innovative approaches and effective bioremediation techniques for clean-up of the contaminant plume have been established.

  3. Providing protection: Agencies receive funding to repair, upgrade dams

    E-Print Network [OSTI]

    Wythe, Kathy

    2009-01-01T23:59:59.000Z

    Story by Kathy Wythe tx H2O | pg. 26 Providing protection Agencies receive funding to repair, upgrade dams along with local partners, can apply for grant funds, he said. Construction of the dams began through four federal authorizations..., called floodwater retarding structures and built mostly in rural areas during the 1950s to 1970s, are aging and need repairing. Others now protect urban areas that have developed downstream and need upgrading to meet more stringent safety standards...

  4. SU-E-I-97: Smart Auto-Planning Framework in An EMR Environment (SAFEE)

    SciTech Connect (OSTI)

    Zhang, B; Chen, S; Mutaf, Y; Prado, K; D'Souza, W [University of Maryland School of Medicine, Baltimore, MD (United States)

    2014-06-01T23:59:59.000Z

    Purpose: Our Radiation Oncology Department uses clinical practice guidelines for patient treatment, including normal tissue sparing and other dosimetric constraints. These practice guidelines were adapted from national guidelines, clinical trials, literature reviews, and practitioner's own experience. Modern treatment planning systems (TPS) have the capability of incorporating these practice guidelines to automatically create radiation therapy treatment plans with little human intervention. We are developing a software infrastructure to integrate clinical practice guidelines and radiation oncology electronic medical record (EMR) system into radiation therapy treatment planning system (TPS) for auto planning. Methods: Our Smart Auto-Planning Framework in an EMR environment (SAFEE) uses a software pipeline framework to integrate practice guidelines,EMR, and TPS together. The SAFEE system starts with retrieving diagnosis information and physician's prescription from the EMR system. After approval of contouring, SAFEE will automatically create plans according to our guidelines. Based on clinical objectives, SAFEE will automatically select treatment delivery techniques (such as, 3DRT/IMRT/VMAT) and optimize plans. When necessary, SAFEE will create multiple treatment plans with different combinations of parameters. SAFEE's pipeline structure makes it very flexible to integrate various techniques, such as, Model-Base Segmentation (MBS) and plan optimization algorithms, e.g., Multi-Criteria Optimization (MCO). In addition, SAFEE uses machine learning, data mining techniques, and an integrated database to create clinical knowledgebase and then answer clinical questions, such as, how to score plan quality or how volume overlap affects physicians' decision in beam and treatment technique selection. Results: In our institution, we use Varian Aria EMR system and RayStation TPS from RaySearch, whose ScriptService API allows control by external programs. These applications are the building blocks of our SAFEE system. Conclusion: SAFEE is a feasible method of integrating clinical information to develop an auto-planning paradigm to improve clinical workflow in cancer patient care.

  5. Auto/Steel Partnership: Advanced High-Strength Steel Research and

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureComments from TarasaName4ServicesTribal RenewableAustinAuto

  6. Pulse-excited, auto-zeroing multiple channel data transmission system

    DOE Patents [OSTI]

    Fasching, George E. (Morgantown, WV)

    1987-01-01T23:59:59.000Z

    A multiple channel data transmission system is provided in which signals from a plurality of pulse operated transducers and a corresponding plurality of pulse operated signal processor channels are multiplexed for single channel FM transmission to a receiving station. The transducers and corresponding channel amplifiers are powered by pulsing the dc battery power to these devices to conserve energy and battery size for long-term data transmission from remote or inaccessible locations. Auto zeroing of the signal channel amplifiers to compensate for drift associated with temperature changes, battery decay, component aging, etc., in each channel is accomplished by means of a unique auto zero feature which between signal pulses holds a zero correction voltage on an integrating capacitor coupled to the corresponding channel amplifier output. Pseudo-continuous outputs for each channel are achieved by pulsed sample-and-hold circuits which are updated at the pulsed operation rate. The sample-and-hold outputs are multiplexed into an FM/FM transmitter for transmission to an FM receiver station for demultiplexing and storage in separate channel recorders.

  7. Pulse-excited, auto-zeroing multiple channel data transmission system

    DOE Patents [OSTI]

    Fasching, G.E.

    1985-02-22T23:59:59.000Z

    A multiple channel data transmission system is provided in which signals from a plurality of pulse operated transducers and a corresponding plurality of pulse operated signal processor channels are multiplexed for single channel FM transmission to a receiving station. The transducers and corresponding channel amplifiers are powered by pulsing the dc battery power to these devices to conserve energy and battery size for long-term data transmission from remote or inaccessible locations. Auto zeroing of the signal channel amplifiers to compensate for drift associated with temperature changes, battery decay, component aging, etc., in each channel is accomplished by means of a unique auto zero feature which between signal pulses holds a zero correction voltage on an integrating capacitor coupled to the corresponding channel amplifier output. Pseudo-continuous outputs for each channel are achieved by pulsed sample-and-hold circuits which are updated at the pulsed operation rate. The sample-and-hold outputs are multiplexed into an FM/FM transmitter for transmission to an FM receiver station for demultiplexing and storage in separate channel recorders.

  8. Polymer nanocomposites for high-temperature composite repair

    SciTech Connect (OSTI)

    Sheng, Xia

    2008-12-01T23:59:59.000Z

    A novel repair agent for resin-injection repair of advanced high temperature composites was developed and characterized. The repair agent was based on bisphenol E cyanate ester (BECy) and reinforced with alumina nanoparticles. To ensure good dispersion and compatibility with the BECy matrix in nanocomposites, the alumina nanoparticles were functionalized with silanes. The BECy nanocomposites, containing bare and functionalized alumina nanoparticles, were prepared and evaluated for their thermal, mechanical, rheological, and viscoelastic properties. The monomer of BECy has an extremely low viscosity at ambient temperature, which is good for processability. The cured BECy polymer is a highly cross-linked network with excellent thermal mechanical properties, with a high glass transition temperature (T{sub g}) of 270 C and decomposition temperature above 350 C. The incorporation of alumina nanoparticles enhances the mechanical and rheological properties of the BECy nanocomposites. Additionally, the alumina nanoparticles are shown to catalyze the cure of BECy. Characterization of the nanocomposites included dynamic mechanical analysis, differential scanning calorimetry, thermogravimetric analysis, rheological and rheokinetic evaluation, and transmission electron microscopy. The experimental results show that the BECy nanocomposite is a good candidate as repair agent for resin-injection repair applications.

  9. The SWAP SHOP: A surplus materials exchange network at DOE`s Oak Ridge Reservation

    SciTech Connect (OSTI)

    Bell, L.H.; Birch-Kennedy, S.

    1993-12-31T23:59:59.000Z

    The diversity and continually changing nature of the research and production programs at the ORR plant sites, as well as the size of the facilities and their physical separation on the ORR, lead to the buildup of surplus equipment and materials from canceled or completed projects, changes in work orders or directives, or over-procurement of particular items or materials. Many times, for lack of a means to find legitimate uses for these excess items, they have been disposed of as wastes or sold as salvage. Recognizing that this situation prevails at most, if not all, government facilities, Congress has enacted legislation encouraging the establishment of waste minimization, pollution prevention, and cost avoidance measures throughout government-owned facilities. In response to this, the Secretary of Energy has instituted a high-priority DOE initiative to develop, promote, and implement waste minimization and pollution prevention at government installations. One result of the increased awareness and emphasis on environmental concerns and improved resource management is the recent grassroots development of a surplus materials exchange network developed and operated on a voluntary basis by Environmental Protection Officers (EPOs) at the Oak Ridge installations. The EPOs are full-time or part-time staff members employed by each division to provide guidance and assistance for achieving compliance with all environmental regulatory requirements and to resolve waste disposal problems. The materials exchange network, called the SWAP SHOP, provides an EPO communications and problem-solving network to help eliminate unnecessary disposal of usable surplus chemicals and equipment at the Oak Ridge plant sites.

  10. Repairs for damaged bolt holes in continuous fiber reinforced plastics 

    E-Print Network [OSTI]

    Copps, Kevin Daniel

    1992-01-01T23:59:59.000Z

    repair method for damaged bolt holes in such composites. Bolt holes in three types of graphite-epoxy were purposely damaged and then repaired. Each was tested to characterize its static and fatigue behavior. The tests used a special fixture to simulate... composite joints . Bearing-bypass ratio can change the failure mode of bolted composite joints 7 Drilling defects in graphite-epoxy coupons 12 26 The exit side of a IM7/8551-7A 18 ply tape coupon showing the damage due to drilling 27 9 Resin filled...

  11. Building Sport Brands with Music: The Impact of Sport Brand Music on the Shopping Behaviors of Sport Consumers

    E-Print Network [OSTI]

    Ballouli, Khalid

    2012-10-19T23:59:59.000Z

    Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Approved by: Chair of Committee, Gregg Bennett Committee Members, George B. Cunningham John N.... (August 2011) Khalid Walid Ballouli, B.S., Texas A&M University; M.S., Texas A&M University Chair of Advisory Committee: Dr. Gregg Bennett This study examines the effects of sport brand music on the shopping behaviors of sport consumers. Sport...

  12. Development of criteria for fatigue repairs in bridge girders damaged by out-of-plane distortion

    E-Print Network [OSTI]

    Wilson, Scott David

    1994-01-01T23:59:59.000Z

    repaired and unrepaired cracks along the longitudinal web-to-flange connection of a plate girder subjected to a linear bending stress to determine if repair by drilling holes is really necessary. The results of the finite element analyses...

  13. DNA Repair Decline During Mouse Spermiogenesis Results in the Accumulation of Heritable DNA Damage

    E-Print Network [OSTI]

    Marchetti, Francesco

    2008-01-01T23:59:59.000Z

    van Buul, D.G. de Rooij, DNA double-strand breaks and gamma-for the transition proteins in DNA strand break repair, FEBSBoissonneault, Stimulation of DNA repair by the spermatidal

  14. Characterization of Mg Binding to the DNA Repair ProteinApurinic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mg Binding to the DNA Repair Protein ApurinicApyrimidic Endonuclease 1 via Solid-State Mg NMR Spectroscopy. Characterization of Mg Binding to the DNA Repair Protein Apurinic...

  15. DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage

    E-Print Network [OSTI]

    Marchetti, Francesco

    2008-01-01T23:59:59.000Z

    van Buul, D.G. de Rooij, DNA double-strand breaks and gamma-for the transition proteins in DNA strand break repair, FEBSBoissonneault, Stimulation of DNA repair by the spermatidal

  16. An engineering analysis of natural and biomimetic self-repair processes for solar energy harvesting

    E-Print Network [OSTI]

    Boghossian, Ardemis A. (Ardemis Anoush)

    2012-01-01T23:59:59.000Z

    Plants have evolved highly sophisticated mechanisms of self-repair to regenerate proteins that become photo-damaged over time. Key to this self-repair process is the reversible self-assembly of protein complexes, which is ...

  17. Combining Regressive and Auto-Regressive Models for Spatial-Temporal Dragoljub Pokrajac DPOKRAJA@EECS.WSU.EDU

    E-Print Network [OSTI]

    Obradovic, Zoran

    of accuracy for both linear and non-linear regression models. The obtained experimental results suggest impact on accuracy of an auto-regression model. For non-linear phenomena, learning algorithms that model grid. The proposed method combines linear or non-linear non-spatial and non- temporal regression models

  18. AutoSense: Unobtrusively Wearable Sensor Suite for Inferring the Onset, Causality, and Consequences of Stress in the Field

    E-Print Network [OSTI]

    Kumar, Santosh

    Applications]: Social and Behav- ioral Sciences General Terms Design, experimentation, measurement, human, Somnath Mitra ,Taewoo Kwon, Jae Woong Jeong The Ohio State University, University of Memphis, University stress and other rich human behav- iors. AutoSense was used in a 20+ subject real-life scientific study

  19. AutoCAD Tutorial # 1: Nidhi Vaid Creating a Footprint Map of a Community Using an Aerial Photograph

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    Standard toolbar Draw toolbar Modify toolbar Command Line #12;AutoCAD Tutorial # 1: Nidhi Vaid Creating. All the objects in the drawing space are considered entities such as lines, arcs, circles, text-axis up the screen and positive Z-axis coming out of the screen towards the user). For example, lines

  20. How to Reach ISI Delhi While booking an auto or a taxi to ISI, mention two wellknown landmarks: Qutab Hotel

    E-Print Network [OSTI]

    Bandyopadhyay, Antar

    How to Reach ISI Delhi While booking an auto or a taxi to ISI, mention two wellknown landmarks: Qutab Hotel (ISI is about 300 meters away from the Qutab Hotel) or Katwaria Sarai (which is the locality where ISI belongs and is directly opposite to the Katwaria Sarai bus stop). For the exact location click

  1. Auto-oligomerization and hydration of pyrrole revealed by x-ray absorption spectroscopy

    SciTech Connect (OSTI)

    Advanced Light Source; Schwartz, Craig P.; Uejio, Janel S.; Duffin, Andrew M.; England, Alice H.; Prendergast, David; Saykally, Richard J

    2009-05-29T23:59:59.000Z

    Near edge x-ray absorption fine structure (NEXAFS) spectra have been measured at the carbon and nitrogen K-edges of the prototypical aromatic molecule, pyrrole, both in the gas phase and when solvated in water, and compared with spectra simulated using a combination of classical molecular dynamics and first principles density functional theory in the excited state core hole approximation. The excellent agreement enabled detailed assignments. Pyrrole is highly reactive, particularly in water, and reaction products formed by the auto-oligomerization of pyrrole are identified. The solvated spectra have been measured at two different temperatures, indicating that the final states remain largely unaffected by both hydration and temperature. This is somewhat unexpected, since the nitrogen in pyrrole can donate a hydrogen bond to water.

  2. The Need for Language Repair The Reformation Algorithm Discussion Reformation: A Domain-Independent Algorithm

    E-Print Network [OSTI]

    St Andrews, University of

    The Need for Language Repair The Reformation Algorithm Discussion Reformation: A Domain of Edinburgh University of St Andrews, 27th November 2013 #12;The Need for Language Repair The Reformation Algorithm Discussion Outline 1 The Need for Language Repair 2 The Reformation Algorithm 3 Discussion #12;The

  3. Development of quick repairing technique for ceramic burner in hot stove of blast furnace

    SciTech Connect (OSTI)

    Kondo, Atsushi; Doura, Kouji; Nakamura, Hirofumi [Sumitomo Metal Industries, Ltd., Wakayama (Japan). Wakayama Steel Works

    1997-12-31T23:59:59.000Z

    Refractories of ceramic burner in hot stoves at Wakayama No. 4 blast furnace were damaged. There are only three hot stoves, so repairing must be done in a short. Therefore, a quick repairing technique for ceramic burners has been developed, and two ceramic burners were repaired in just 48 hours.

  4. Self-Calibration for 3-point Intrinsic Alignment Auto-Correlations in Weak Lensing Surveys

    E-Print Network [OSTI]

    M. A. Troxel; Mustapha Ishak

    2012-03-09T23:59:59.000Z

    The weak lensing signal (cosmic shear) has been shown to be strongly contaminated by the various types of galaxy intrinsic alignment (IA) correlations, which poses a barrier to precision weak lensing measurements. The redshift dependence of the IA signal has been used at the 2-point level to reduce this contamination by only measuring cross-correlations between large redshift bins, which significantly reduces the galaxy intrinsic ellipticity - intrinsic ellipticity (II) correlation. A self-calibration technique based on the redshift dependences of the IA correlations has also been proposed as a means to remove the 2-point IA contamination from the lensing signal. We explore here the redshift dependences of the IA and lensing bispectra in order to propose a self-calibration of the IA auto-correlations at the 3-point level (i.e. GGI, GII, and III), which can be well understood without the assumption of any particular IA model. We find that future weak lensing surveys will be able to measure the distinctive IA redshift dependence over ranges of $|\\Delta z^P|\\le 0.2$. Using conservative estimates of photo-z accuracy, we describe the 3-point self-calibration technique for the total IA signal, which can be accomplished through lensing tomography of photo-z bin size $\\sim 0.01$. We find that the 3-point self-calibration can function at the accuracy of the 2-point technique with modest constraints in redshift separation. This allows the 3-point IA auto-correlation self-calibration technique proposed here to significantly reduce the contamination of the IA contamination to the weak lensing bispectrum.

  5. HOW TO REPAIR A SECOND-ORDER SURFACE FOR COMPUTER

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 HOW TO REPAIR A SECOND-ORDER SURFACE FOR COMPUTER EXPERIMENTS BY KRIGING Astrid JOURDAN and analysis of computer experiments have been widely investigated in the past decade. Two approaches seem describes and compares them briefly in order to present a methodology for computer experiments based

  6. Thermosetting Polymer-Matrix Composites for Strucutral Repair Applications

    SciTech Connect (OSTI)

    William Kirby Goertzen

    2007-12-01T23:59:59.000Z

    Several classes of thermosetting polymer matrix composites were evaluated for use in structural repair applications. Initial work involved the characterization and evaluation of woven carbon fiber/epoxy matrix composites for structural pipeline repair. Cyanate ester resins were evaluated as a replacement for epoxy in composites for high-temperature pipe repair applications, and as the basis for adhesives for resin infusion repair of high-temperature composite materials. Carbon fiber/cyanate ester matrix composites and fumed silica/cyanate ester nanocomposites were evaluated for their thermal, mechanical, viscoelastic, and rheological properties as they relate to their structure, chemistry, and processing characteristics. The bisphenol E cyanate ester under investigation possesses a high glass transition temperature, excellent mechanical properties, and unique ambient temperature processability. The incorporate of fumed silica served to enhance the mechanical and rheological properties of the polymer and reduce thermal expansion without sacrificing glass transition or drastically altering curing kinetics. Characterization of the composites included dynamic mechanical analysis, thermomechanical analysis, differential scanning calorimetry, thermogravimetric analysis, rheological and rheokinetic evaluation, and transmission electron microscopy.

  7. Development/Plasticity/Repair Identification of Nicotinic Acetylcholine Receptor Recycling

    E-Print Network [OSTI]

    Alford, Simon

    Development/Plasticity/Repair Identification of Nicotinic Acetylcholine Receptor Recycling and Its, University of Michigan, Ann Arbor, Michigan 48109 In the CNS, receptor recycling is critical for synaptic plasticity; however, the recycling of receptors has never been observed at peripheral synapses. Using a novel

  8. Corrosion Repair and Corrosion Protection of Reinforced Concrete Structures in

    E-Print Network [OSTI]

    Das, Suman

    11/14/2014 1 Corrosion Repair and Corrosion Protection of Reinforced Concrete Structures in Pulp and Paper Mills Vector Construction / Vector Corrosion Technologies www.vectorgroup.com www.vector-corrosion.com Presentation Outline · Introduction · Corrosion of Reinforced Concrete Structures · Protection of Chests

  9. Methods to alter levels of a DNA repair protein

    DOE Patents [OSTI]

    Petrini, John H.; Morgan, William Francis; Maser, Richard Scott; Carney, James Patrick

    2006-10-17T23:59:59.000Z

    An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

  10. Breakthrough Technologies In Vivo Observation of Cavitation and Embolism Repair

    E-Print Network [OSTI]

    Holbrook, N. Michele

    Breakthrough Technologies In Vivo Observation of Cavitation and Embolism Repair Using Magnetic that approximately 10 vessels had cavitated during this time. Leaf water potentials decreased from 1.25 to 2.1 MPa cavitation. Refilling of xylem vessels occurred as soon as the lights were switched off, with the majority

  11. Development/Plasticity/Repair Group I Metabotropic Glutamate Receptors Control

    E-Print Network [OSTI]

    Grau, James

    Development/Plasticity/Repair Group I Metabotropic Glutamate Receptors Control Metaplasticity the spinal cord can support several forms of plasticity, including response­outcome (instrumental) learning. This inhibi- tion of plasticity in spinal learning is itself a form of plasticity that requires i

  12. Complications of Endovascular Repair of Abdominal Aortic Aneurysms: A Review

    SciTech Connect (OSTI)

    Katzen, Barry T. [Baptist Cardiac and Vascular Institute, Baptist Health Systems, Department of Interventional Radiology, Florida (United States)], E-mail: barryk@baptisthealth.net; MacLean, Alexandra A. [New York Hospital-Queens, Department of Surgery (United States)

    2006-12-15T23:59:59.000Z

    The endovascular procedure for repair of abdominal aortic aneurysms has had an enormous impact on the treatment of this challenging disease. Complications, however, do occur and it is important to have a thorough understanding of the array of complications and appropriate management strategies. In this review of endovascular complications, we describe early and late complications paying particular attention to preventive, treatment and surveillance strategies.

  13. Make Model SPECS ACURA ILX (Model Year 2013) 2.0L 4, auto stk [P] ULEV II / Bin 5 45

    E-Print Network [OSTI]

    II / Bin 5 42 BMW 328i (Model Year 2013) 2.0L 4, auto stk [P] Bin 5 / ULEV II 42 BMW 328i (Model Year 2013) 2.0L 4, manual [P] ULEV II / Bin 5 43 BMW 328i XDRIVE (Model Year 2013) 2.0L 4, auto stk Awd [P] ULEV II / Bin 5 41 BMW 335i (Model Year 2013) 3.0L 6, auto stk [P] ULEV II / Bin 5 41 BMW 528i (Model

  14. MEMBERS ONLY | Join | Renew | Shop | About | Contact Us | Home ASME.ORG > News & Public Policy > Press Releases > Research Begun on New Fuel Cell Type

    E-Print Network [OSTI]

    SEARCH ASME: MEMBERS ONLY | Join | Renew | Shop | About | Contact Us | Home ASME.ORG > News Type NEW YORK, June 25, 2004 - In the June 2004 issue of Mechanical Engineering, a publication of ASME the potential to generate 2.3 megawatts of electricity, or enough energy to power 1,500 homes. One of the fuel

  15. Combined Haploinsufficiency for ATM and RAD9 as a Factor in Cell Transformation, Apoptosis, and DNA Lesion Repair Dynamics

    E-Print Network [OSTI]

    Lesion Repair Dynamics Lubomir B. Smilenov, Howard B. Lieberman, Stephen A. Mitchell, Ronald A. Baker

  16. Biomolecular Simulation of Base Excision Repair and Protein Signaling

    SciTech Connect (OSTI)

    Straatsma, TP; McCammon, J. A.; Miller, John H.; Smith, Paul E.; Vorpagel, Erich R.; Wong, Chung F.; Zacharias, Martin W.

    2006-03-03T23:59:59.000Z

    The goal of the Biomolecular Simulation of Base Excision Repair and Protein Signaling project is to enhance our understanding of the mechanism of human polymerase-?, one of the key enzymes in base excision repair (BER) and the cell-signaling enzymes cyclic-AMP-dependent protein kinase. This work used molecular modeling and simulation studies to specifically focus on the • dynamics of DNA and damaged DNA • dynamics and energetics of base flipping in DNA • mechanism and fidelity of nucleotide insertion by BER enzyme human polymerase-? • mechanism and inhibitor design for cyclic-AMP-dependent protein kinase. Molecular dynamics simulations and electronic structure calculations have been performed using the computer resources at the Molecular Science Computing Facility at the Environmental Molecular Sciences Laboratory.

  17. A 32-channel photon counting module with embedded auto/cross-correlators for real-time parallel fluorescence correlation spectroscopy

    SciTech Connect (OSTI)

    Gong, S.; Labanca, I.; Rech, I.; Ghioni, M. [Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy)

    2014-10-15T23:59:59.000Z

    Fluorescence correlation spectroscopy (FCS) is a well-established technique to study binding interactions or the diffusion of fluorescently labeled biomolecules in vitro and in vivo. Fast FCS experiments require parallel data acquisition and analysis which can be achieved by exploiting a multi-channel Single Photon Avalanche Diode (SPAD) array and a corresponding multi-input correlator. This paper reports a 32-channel FPGA based correlator able to perform 32 auto/cross-correlations simultaneously over a lag-time ranging from 10 ns up to 150 ms. The correlator is included in a 32 × 1 SPAD array module, providing a compact and flexible instrument for high throughput FCS experiments. However, some inherent features of SPAD arrays, namely afterpulsing and optical crosstalk effects, may introduce distortions in the measurement of auto- and cross-correlation functions. We investigated these limitations to assess their impact on the module and evaluate possible workarounds.

  18. Testing and evaluation of grout repaired tubular members 

    E-Print Network [OSTI]

    Nunn, John Mansfield

    1992-01-01T23:59:59.000Z

    of Failed Weld Seam page 64 65 66 69 73 74 80 82 31 Ideahzed Tubular Dented Member for the Taby, Zhou, and the Parsanejad Methods. . . . . . . . . . . . . . , . 92 32 Dent Geometry for the Elhnas Method 96 33 Experimental Ultimate Capamty vs P... commonly used to repiur damaged tubular members. These include 1 ) welding a sleeve around the outside of the member in the location of the damage, 2 ) applying an externally grouted clamp, and 3 ) applying internal grout Ideally, the repair method...

  19. Waste-audit study: Automotive repairs. Final report

    SciTech Connect (OSTI)

    Toy, W.M.

    1987-05-01T23:59:59.000Z

    This document reports on a waste audit study which investigated and analyzed the automotive-repair industry in California. It assessed current waste-management practices and developed specific on-site and off-site waste-treatment recycling alternatives. The conclusions identify and address illegal disposal practices. Recommendations include the segregation of specific wastes for proper disposal and economic analysis of on-site waste-recycling equipment.

  20. High density growth of T7 expression strains with auto-induction option

    DOE Patents [OSTI]

    Studier, F. William (Stony Brook, NY)

    2009-07-14T23:59:59.000Z

    Disclosed is a method for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise, the transcription being under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells. Initially, a culture media is provided which includes: i) an inducer that causes induction of transcription from said promoter in said bacterial cells; and ii) a metabolite that prevents induction by said inducer, the concentration of said metabolite being adjusted so as to substantially preclude induction by said inducer in the early stages of growth of the bacterial culture, but such that said metabolite is depleted to a level that allows induction by said inducer at a later stage of growth. The culture medium is inoculated with a bacterial inoculum, the inoculum comprising bacterial cells containing cloned DNA, the transcription of which is induced by said inducer. The culture is then incubated under conditions appropriate for growth of the bacterial cells.

  1. Resource-Efficient, Hierarchical Auto-Tuning of a Hybrid Lattice Boltzmann Computation on the Cray XT4

    SciTech Connect (OSTI)

    Computational Research Division, Lawrence Berkeley National Laboratory; NERSC, Lawrence Berkeley National Laboratory; Computer Science Department, University of California, Berkeley; Williams, Samuel; Carter, Jonathan; Oliker, Leonid; Shalf, John; Yelick, Katherine

    2009-05-04T23:59:59.000Z

    We apply auto-tuning to a hybrid MPI-pthreads lattice Boltzmann computation running on the Cray XT4 at National Energy Research Scientific Computing Center (NERSC). Previous work showed that multicore-specific auto-tuning can improve the performance of lattice Boltzmann magnetohydrodynamics (LBMHD) by a factor of 4x when running on dual- and quad-core Opteron dual-socket SMPs. We extend these studies to the distributed memory arena via a hybrid MPI/pthreads implementation. In addition to conventional auto-tuning at the local SMP node, we tune at the message-passing level to determine the optimal aspect ratio as well as the correct balance between MPI tasks and threads per MPI task. Our study presents a detailed performance analysis when moving along an isocurve of constant hardware usage: fixed total memory, total cores, and total nodes. Overall, our work points to approaches for improving intra- and inter-node efficiency on large-scale multicore systems for demanding scientific applications.

  2. Using 3D Painting to Build and Repair Parts | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a part or add material to repair an existing part. Cold spray is part of GE's expanded additive manufacturing toolkit. An error occurred. Unable to execute Javascript. nteneh...

  3. Brain necrosis after fractionated radiation therapy: Is the halftime for repair longer than we thought?

    SciTech Connect (OSTI)

    Bender, Edward T. [Department of Human Oncology, University of Wisconsin-Madison, School of Medicine and Public Health, 600 Highland Avenue, Madison, Wisconsin 53792 (United States)

    2012-11-15T23:59:59.000Z

    Purpose: To derive a radiobiological model that enables the estimation of brain necrosis and spinal cord myelopathy rates for a variety of fractionation schemes, and to compare repair effects between brain and spinal cord. Methods: Sigmoidal dose response relationships for brain radiation necrosis and spinal cord myelopathy are derived from clinical data using nonlinear regression. Three different repair models are considered and the repair halftimes are included as regression parameters. Results: For radiation necrosis, a repair halftime of 38.1 (range 6.9-76) h is found with monoexponential repair, while for spinal cord myelopathy, a repair halftime of 4.1 (range 0-8) h is found. The best-fit alpha beta ratio is 0.96 (range 0.24-1.73)Conclusions: A radiobiological model that includes repair corrections can describe the clinical data for a variety of fraction sizes, fractionation schedules, and total doses. Modeling suggests a relatively long repair halftime for brain necrosis. This study suggests that the repair halftime for late radiation effects in the brain may be longer than is currently thought. If confirmed in future studies, this may lead to a re-evaluation of radiation fractionation schedules for some CNS diseases, particularly for those diseases where fractionated stereotactic radiation therapy is used.

  4. Acceleration of electrons using an inverse free electron laser auto- accelerator

    SciTech Connect (OSTI)

    Wernick, I.K.; Marshall, T.C.

    1992-07-01T23:59:59.000Z

    We present data from our study of a device known as the inverse free electron laser. First, numerical simulations were performed to optimize the design parameters for an experiment that accelerates electrons in the presence of an undulator by stimulated absorption of radiation. The Columbia free electron laser (FEL) was configured as an auto-accelerator (IFELA) system; high power (MW`s) FEL radiation at {approximately}1.65 mm is developed along the first section of an undulator inside a quasi-optical resonator. The electron beam then traverses a second section of undulator where a fraction of the electrons is accelerated by stimulated absorption of the 1.65 mm wavelength power developed in the first undulator section. The second undulator section has very low gain and does not generate power on its own. We have found that as much as 60% of the power generated in the first section can be absorbed in the second section, providing that the initial electron energy is chosen correctly with respect to the parameters chosen for the first and second undulators. An electron momentum spectrometer is used to monitor the distribution of electron energies as the electrons exit the IFELA. We have found; using our experimental parameters, that roughly 10% of the electrons are accelerated to energies as high as 1100 keV, in accordance with predictions from the numerical model. The appearance of high energy electrons is correlated with the abrupt absorption of millimeter power. The autoaccelerator configuration is used because there is no intense source of coherent power at the 1.65 mm design wavelength other than the FEL.

  5. Acceleration of electrons using an inverse free electron laser auto- accelerator

    SciTech Connect (OSTI)

    Wernick, I.K.; Marshall, T.C.

    1992-07-01T23:59:59.000Z

    We present data from our study of a device known as the inverse free electron laser. First, numerical simulations were performed to optimize the design parameters for an experiment that accelerates electrons in the presence of an undulator by stimulated absorption of radiation. The Columbia free electron laser (FEL) was configured as an auto-accelerator (IFELA) system; high power (MW's) FEL radiation at {approximately}1.65 mm is developed along the first section of an undulator inside a quasi-optical resonator. The electron beam then traverses a second section of undulator where a fraction of the electrons is accelerated by stimulated absorption of the 1.65 mm wavelength power developed in the first undulator section. The second undulator section has very low gain and does not generate power on its own. We have found that as much as 60% of the power generated in the first section can be absorbed in the second section, providing that the initial electron energy is chosen correctly with respect to the parameters chosen for the first and second undulators. An electron momentum spectrometer is used to monitor the distribution of electron energies as the electrons exit the IFELA. We have found; using our experimental parameters, that roughly 10% of the electrons are accelerated to energies as high as 1100 keV, in accordance with predictions from the numerical model. The appearance of high energy electrons is correlated with the abrupt absorption of millimeter power. The autoaccelerator configuration is used because there is no intense source of coherent power at the 1.65 mm design wavelength other than the FEL.

  6. A sociotechnical framework for understanding infrastructure breakdown and repair

    SciTech Connect (OSTI)

    Sims, Benjamin H [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    This paper looks at how and why infrastructure is repaired. With a new era of infrastructure spending underway, policymakers need to understand and anticipate the particular technical and political challenges posed by infrastructure repair. In particular, as infrastructure problems are increasingly in the public eye with current economic stimulus efforts, the question has increasingly been asked: why has it been so difficult for the United Statesto devote sustained resources to maintaining and upgrading its national infrastructure? This paper provides a sociotechnical framework for understanding the challenges of infrastructure repair, and demonstrates this framework using a case study of seismic retrofit of freeway bridges in California. The design of infrastructure is quite different from other types of design work even when new infrastructure is being designed. Infrastructure projects are almost always situated within, and must work with, existing infrastructure networks. As a result, compared to design of more discrete technological artifacts, the design of infrastructure systems requires a great deal of attention to interfaces as well as adaptation of design to the constraints imposed by existing systems. Also, because of their scale, infrastructural technologies engage with social life at a level where explicit political agendas may playa central role in the design process. The design and building of infrastructure is therefore often an enormously complex feat of sociotechnical engineering, in which technical and political agendas are negotiated together until an outcome is reached that allows the project to move forward. These sociotechnical settlements often result in a complex balancing of powerful interests around infrastructural artifacts; at the same time, less powerful interests have historically often been excluded or marginalized from such settlements.

  7. Repair welding of fusion reactor components. Final technical report

    SciTech Connect (OSTI)

    Chin, B.A.; Wang, C.A.

    1997-09-30T23:59:59.000Z

    The exposure of metallic materials, such as structural components of the first wall and blanket of a fusion reactor, to neutron irradiation will induce changes in both the material composition and microstructure. Along with these changes can come a corresponding deterioration in mechanical properties resulting in premature failure. It is, therefore, essential to expect that the repair and replacement of the degraded components will be necessary. Such repairs may require the joining of irradiated materials through the use of fusion welding processes. The present ITER (International Thermonuclear Experimental Reactor) conceptual design is anticipated to have about 5 km of longitudinal welds and ten thousand pipe butt welds in the blanket structure. A recent study by Buende et al. predict that a failure is most likely to occur in a weld. The study is based on data from other large structures, particularly nuclear reactors. The data used also appear to be consistent with the operating experience of the Fast Flux Test Facility (FFTF). This reactor has a fuel pin area comparable with the area of the ITER first wall and has experienced one unanticipated fuel pin failure after two years of operation. The repair of irradiated structures using fusion welding will be difficult due to the entrapped helium. Due to its extremely low solubility in metals, helium will diffuse and agglomerate to form helium bubbles after being trapped at point defects, dislocations, and grain boundaries. Welding of neutron-irradiated type 304 stainless steels has been reported with varying degree of heat-affected zone cracking (HAZ). The objectives of this study were to determine the threshold helium concentrations required to cause HAZ cracking and to investigate techniques that might be used to eliminate the HAZ cracking in welding of helium-containing materials.

  8. Blade reliability collaborative : collection of defect, damage and repair data.

    SciTech Connect (OSTI)

    Ashwill, Thomas D.; Ogilvie, Alistair B.; Paquette, Joshua A.

    2013-04-01T23:59:59.000Z

    The Blade Reliability Collaborative (BRC) was started by the Wind Energy Technologies Department of Sandia National Laboratories and DOE in 2010 with the goal of gaining insight into planned and unplanned O&M issues associated with wind turbine blades. A significant part of BRC is the Blade Defect, Damage and Repair Survey task, which will gather data from blade manufacturers, service companies, operators and prior studies to determine details about the largest sources of blade unreliability. This report summarizes the initial findings from this work.

  9. Rebels, Activists, and Repairers: Youth and Social Change in Africa

    E-Print Network [OSTI]

    Pollock, Colleen

    2011-12-31T23:59:59.000Z

    #3;answer#3;questions#3; (Irvine#3;1978)#3;(i.e.#3;?“what#3;does#3;the#3;ducky#3;say??”)#3;because#3;such#3;questioning#3;indicates#3;a#3;riddle#3;with#3; a#3;trick#3;answer#3;or#3;a#3;direct#3;challenge,#3;and#3;it#3;is#3;considered#3;an#3;insult#3... Date Defended: May 17, 2011 #3; #3; #3; #3; #3; #3; ii #3; The Thesis Committee for Colleen Pollock certifies that this is the approved version of the following thesis: REBELS, ACTIVISTS, AND REPAIRERS: THE ROLE OF YOUTH IN SOCIAL CHANGE...

  10. Repairs for damaged bolt holes in continuous fiber reinforced plastics

    E-Print Network [OSTI]

    Copps, Kevin Daniel

    1992-01-01T23:59:59.000Z

    ANALYSIS Model Definition Analysis Results Comparing Lay-ups Pin-conditions vs. clamping pressure Stress interactions Repair material CONCLUSIONS REFERENCES APPENDIX VITA 21 22 23 24 25 25 25 26 27 27 28 29 30 30 31 33 33 34 34... under pin conditions . 35 16 A modification was made to the test fixture to relieve the high cyclic stresses on the bolt 37 vu 17 When clamping pressure is applied, a normally drilled, unrepaired, fastener hole is stronger and tends to fail in net...

  11. Project Final Report: Building a Community Infrastructure for Scalable On-Line Performance Analysis Tools around Open|SpeedShop

    SciTech Connect (OSTI)

    Galarowicz, James

    2014-01-06T23:59:59.000Z

    In this project we created a community tool infrastructure for program development tools targeting Petascale class machines and beyond. This includes tools for performance analysis, debugging, and correctness tools, as well as tuning and optimization frameworks. The developed infrastructure provides a comprehensive and extensible set of individual tool building components. We started with the basic elements necessary across all tools in such an infrastructure followed by a set of generic core modules that allow a comprehensive performance analysis at scale. Further, we developed a methodology and workflow that allows others to add or replace modules, to integrate parts into their own tools, or to customize existing solutions. In order to form the core modules, we built on the existing Open|SpeedShop infrastructure and decomposed it into individual modules that match the necessary tool components. At the same time, we addressed the challenges found in performance tools for petascale systems in each module. When assembled, this instantiation of community tool infrastructure provides an enhanced version of Open|SpeedShop, which, while completely different in its architecture, provides scalable performance analysis for petascale applications through a familiar interface. This project also built upon and enhances capabilities and reusability of project partner components as specified in the original project proposal. The overall project team’s work over the project funding cycle was focused on several areas of research, which are described in the following sections. The reminder of this report also highlights related work as well as preliminary work that supported the project. In addition to the project partners funded by the Office of Science under this grant, the project team included several collaborators who contribute to the overall design of the envisioned tool infrastructure. In particular, the project team worked closely with the other two DOE NNSA laboratories Los Alamos and Sandia leveraging co-funding for Krell by ASC’s Common Computing Environment (CCE) program as laid out in the original proposal. The ASC CCE co-funding, coordinated through LLNL, was for 50% of the total project funding, with the ASC CCE portion of the funding going entirely to Krell, while the ASCR funding itself was split between Krell and the funded partners. This report covers the entire project from both funding sources. Additionally, the team leveraged the expertise of software engineering researchers from Carnegie Mellon University, who specialize in software framework design, in order to achieve a broadly acceptable component framework. The Component Based Tool Framework (CBTF) software has been released to the community. Information related to the project and the released software can be found on the CBTF wiki page at: http://sourceforge.net/p/cbtf/wiki/Home

  12. Repairs to silence Tower bells | The Daily Texan http://dailytexanonline.com/news/2012/09/27/repairs-to-silence-tower-bells 2 of 4 10/2/2012 8:55 AM

    E-Print Network [OSTI]

    John, Lizy Kurian

    Repairs to silence Tower bells | The Daily Texan http://dailytexanonline.com/news/2012/09/27/repairs-to-silence-tower-bells 2 of 4 10/2/2012 8:55 AM #12;Repairs to silence Tower bells | The Daily Texan http://dailytexanonline.com/news/2012/09/27/repairs-to-silence-tower-bells 3 of 4 10/2/2012 8

  13. Cooperative Repair with Minimum-Storage Regenerating Codes for Distributed Storage

    E-Print Network [OSTI]

    Li, Baochun

    Cooperative Repair with Minimum-Storage Regenerating Codes for Distributed Storage Jun Li, Baochun--Distributed storage systems store redundant data to tolerate failures of storage nodes and lost data should be repaired when storage nodes fail. A class of MDS codes, called minimum- storage regenerating (MSR) codes

  14. 4 CONCRETE REPAIR BULLETIN MAY/JUNE2001 Laser Profilometry for

    E-Print Network [OSTI]

    Maerz, Norbert H.

    4 CONCRETE REPAIR BULLETIN MAY/JUNE2001 Laser Profilometry for Concrete Substrate Characterization and resins are non- corrosive, they are ideally suited for the repair and retrofitting of concrete bridges highly upon the quality of the bond between the concrete and the laminate. Experience has shown that when

  15. On the Design of an Interactive, Patient-Specific Surgical Simulator for Mitral Valve Repair

    E-Print Network [OSTI]

    On the Design of an Interactive, Patient-Specific Surgical Simulator for Mitral Valve Repair Neil A repair of the mitral valve is a difficult procedure that is often avoided in favor of less effective valve replacement because of the associated technical challenges facing non-expert surgeons

  16. Bridge Damage and Repair Costs from Hurricane Katrina Jamie Padgett1

    E-Print Network [OSTI]

    Padgett, Jamie Ellen

    Bridge Damage and Repair Costs from Hurricane Katrina Jamie Padgett1 ; Reginald DesRoches2 ; Bryant caused significant damage to the transportation system in the Gulf Coast region. The overall cost to repair or replace the bridges damaged during the hurricane is estimated at over $1 billion. This paper

  17. Automatic Repair of Buggy If Conditions and Missing Preconditions with SMT

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Automatic Repair of Buggy If Conditions and Missing Preconditions with SMT Favio De into a Satisfiability Modulo Theory (SMT) problem, and translating the SMT result ­ if there exists one ­ into a source, Verification Keywords Automatic repair, test suite, buggy if condition, missing pre- condition, SMT, angelic

  18. Bone Marrow Stimulation of the Medial Femoral Condyle Produces Inferior Cartilage and Bone Repair Compared to the Trochlea in a

    E-Print Network [OSTI]

    Buschmann, Michael

    Bone Marrow Stimulation of the Medial Femoral Condyle Produces Inferior Cartilage and Bone Repair femoral condylar (MFC) versus femoral trochlear (TR) defects 3 months after bone marrow stimulation: cartilage repair; medial femoral condyle; trochlea; bone marrow stimulation; meniscus degeneration Articular

  19. ITERATIVE REPAIR PLANNING FOR SPACECRAFT OPERATIONS USING THE ASPEN SYSTEM Gregg Rabideau, Russell Knight, Steve Chien, Alex Fukunaga, Anita Govindjee

    E-Print Network [OSTI]

    Schaffer, Steven

    ITERATIVE REPAIR PLANNING FOR SPACECRAFT OPERATIONS USING THE ASPEN SYSTEM Gregg Rabideau, Russell and Planning Environment (ASPEN). ASPEN encodes complex spacecraft knowledge of operability constraints, flight generation of low level spacecraft sequences. Using a technique called iterative repair, ASPEN classifies

  20. User data package for implementation of electrolytic recovery technology in Navy electroplating shops. Final report, March 1993-January 1995

    SciTech Connect (OSTI)

    Ford, K.; Koff, J.

    1995-10-01T23:59:59.000Z

    In FY94 the Naval Facilities Engineering Service Center (NFESC) completed tests on three electrolytic recovery systems used for the recovery of metals and destruction of cyanide from electroplating wastewaters. Field testing and evaluation was conducted at NSY Norfolk, NAWC Indianapolis, and NADEP Cherry Pt. for five metal recovery applications: silver cyanide, copper cyanide, acid copper, electroless nickel, and tin-lead fluoborate. Advanced design features for metal recovery, including enhanced fluidized circulation, specialized oxidizing anodes, and high porous surface area cathodes were evaluated to optimize performance. NFESC demonstrated that electrolytic recovery systems can be adapted for effective use in the Navy plating operations where production is often sporadic as contrasted to industrial plating processes. The electrolytic recovery units removed metal ions from the rinsewater to below 1 ppm for each application. Electrowinning, as an alternative technology, can reduce industrial waste treatment costs and hazardous sludge generated from conventional treatment This User Data Package (UDP) covers the design, operational and maintenance requirements for these electrolytic systems. This UDP will be applicable to small Navy plating shops where closed-loop waste recycling and point source minimization is necessary for environmental compliance and cost competitiveness.

  1. Injection repair of carbon fiber/bismaleimide composite panels with bisphenol E cyanate ester resin

    SciTech Connect (OSTI)

    Thunga, Mahendra [Ames Laboratory; Bauer, Amy [Iowa State University; Obusek, Kristine [Fleet Readiness Center East; Meilunas, Ray [Naval Air Warfare Center Aircraft Division; Akinc, Mufit [Ames Laboratory; Kessler, Michael R [Ames Laboratory

    2014-08-01T23:59:59.000Z

    Resin injection of bisphenol E cyanate ester, a low viscosity resin that cures into a high temperature thermoset polymer, is investigated as a reliable repair method to restore strength and stiffness in delaminated carbon fiber/bismaleimide composites used in aircraft panels. The influence of temperature on the viscosity of the uncured resin was measured to optimize the injection conditions for high resin infiltration into the delaminations. The repair efficiency of the resin was evaluated by varying the panel thickness and the method by which the delamination damage was created in the composite specimens. Ultrasonic scanning (C-scan), flash thermography images, and cross-section analysis of repaired panels revealed excellent resin infiltration into the damaged region. Evaluation of mechanical repair efficiency using both bending stiffness and in-plain compressive strength of the composite panels as the repair metrics showed values exceeding 100%.

  2. Repair of gamma-ray-induced DNA base damage in xeroderma pigmentosum cells

    SciTech Connect (OSTI)

    Fornace, A.J. Jr.; Dobson, P.P.; Kinsella, T.J.

    1986-04-01T23:59:59.000Z

    The repair of DNA damage produced by /sup 137/Cs gamma irradiation was measured with a preparation from Micrococcus luteus containing DNA damage-specific endonucleases in combination with alkaline elution. The frequency of these endonuclease sensitive sites (ESS) was determined after 54 or 110 Gy of oxic irradiation in normal and xeroderma pigmentosum (XP) fibroblasts from complementation groups A, C, D, and G. Repair was rapid in all cell strains with greater than 50% repair after 1.5 h of repair incubation. At later repair times, 12-17 h, more ESS remained in XP than in normal cells. The frequency of excess ESS in XP cells was approximately 0.04 per 10(9) Da of DNA per Gy which was equivalent to 10% of the initial ESS produced. The removal of ESS was comparable in XP cells with normal radiosensitivity and XP3BR cells which have been reported to be moderately radiosensitive.

  3. Advanced intelligent coordinated control of coal fired power plant based on fuzzy reasoning and auto-tuning

    SciTech Connect (OSTI)

    Li, S.Y.; Liu, H.B.; Cai, W.J.; Soh, Y.C.; Xie, L.H. [Shanghai Jiao Tong University, Shanghai (China)

    2004-07-01T23:59:59.000Z

    The load following operation of coal-fired boiler-turbine unit in power plants can lead to changes in operating points, and it results in nonlinear variations of the plant variables and parameters. As there exist strong couplings between the main steam pressure control loop and the power output control loop in the boiler-turbine unit with large time-delay and uncertainties, automatic coordinated control of the two loops is a very challenging problem. This paper presents a new coordinated control strategy (CCS) which is organized into two levels: a basic control level and a high supervision level. PID-type controllers are used in the basic level to perform basic control functions while the decoupling between two control loops can be realized in the high level. Moreover, PID-type controllers can be auto-tuned to achieve a better control performance in the whole operating range and to reject the unmeasurable disturbances. A special subclass of fuzzy inference systems, namely the Gaussian partition system with evenly spaced midpoints, is also proposed to auto-tune the PID controller in the main steam pressure loop based on the error signal and its first difference to overcome uncertainties caused by changing fuel calorific value, machine wear, contamination of the boiler heating surfaces and plant modeling errors, etc. The developed CCS has been implemented in a power plant in China, and satisfactory industrial operation results demonstrate that the proposed control strategy has enhanced the adaptability and robustness of the process.

  4. Study on Auto-DR and Pre-Cooling of Commercial Buildings with Thermal Mass in California

    SciTech Connect (OSTI)

    Yin, Rongxin; Xu, Peng; Piette, Mary Ann; Kiliccote, Sila

    2010-01-09T23:59:59.000Z

    This paper discusses how to optimize pre-cooling strategies for buildings in a hot California climate zone with the Demand Response Quick Assessment Tool (DRQAT), a building energy simulation tool. This paper outlines the procedure used to develop and calibrate DRQAT simulation models, and applies this procedure to eleven field test buildings. The results of a comparison between the measured demand savings during the peak period and the savings predicted by the simulation model indicate that the predicted demand shed match well with measured data for the corresponding auto-demand response (Auto-DR) days. The study shows that the accuracy of the simulation models is greatly improved after calibrating the initial models with measured data. These improved models can be used to predict load reductions for automated demand response events. The simulation results were compared with field test data to confirm the actual effect of demand response strategies. Results indicate that the optimal demand response strategies worked well for most of the buildings tested in this hot climate zone.

  5. New Technologies for Repairing Aging Cables in Nuclear Power Plants

    SciTech Connect (OSTI)

    Simmons, Kevin L.; Fifield, Leonard S.; Westman, Matthew P.

    2013-09-11T23:59:59.000Z

    The goal of this project is to demonstrate a proof-of-concept for a technique to repair aging cables that have been subjected to degradation associated with long-term thermal and radiation exposure in nuclear power plants. The physical degradation of the aging cables manifests itself primarily as cracking and increased brittleness of the polymeric electrical insulation. Therefore, the proposed cable-repair concept comprises development of techniques to impart a softening agent within the deteriorated polymer insulation jacket so as to regain the ability of the insulation to stretch without failing and possibly to heal existing cracks in the insulation. Our approach is to use commercially available ethylene-propylene rubber (EPR) as the relevant test material, demonstrate the adsorption of chemical treatments in the EPR and quantify changes in resulting physical and mechanical properties. EPR cable samples have been thermally treated in air to produce specimens corresponding to the full range of cable age-performance points from new (>350% elongation at break) to end-of-life (<50% elongation at break). The current focus is on two chemical treatments selected as candidates for restoring age-related cable elasticity loss: a rubber plasticizer and a reactive silane molecule. EPR specimens of 200, 150, 100, and 50% elongation at break have been soaked in the candidate chemical treatments and the kinetics of chemical uptake, measured by change in mass of the samples, has been determined. Mechanical properties as a function of aging and chemical treatment have been measured including ultimate tensile strength, tensile modulus at 50% strain, elongation at break, and storage modulus. Dimensional changes with treatment and changes in glass transition temperature were also investigated. These ongoing experiments are expected to provide insight into the physical-chemical nature of the effect of thermal degradation on EPR rejuvenation limits and to advance novel methods for restoring the ability of degraded EPR to be compliant and resist fracture. The results of this research reveal that absorption of chemical treatments can lower the glass transition temperature and modulus of EPR. Chemical treatments pursued thus far have proven ineffective at restoring EPR strength and elongation at break. Future work will combine the plasticizer modalities found to successfully increase the volume of the EPR, reduce EPR glass transition temperature and reduce EPR modulus with promising chemistries that will repair the damage of the polymer, potentially using the plasticizer as a host for the new chemistry.

  6. Method of tissue repair using a composite material

    DOE Patents [OSTI]

    Hutchens, Stacy A; Woodward, Jonathan; Evans, Barbara R; O'Neill, Hugh M

    2014-03-18T23:59:59.000Z

    A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

  7. Neurological Complications Following Endoluminal Repair of Thoracic Aortic Disease

    SciTech Connect (OSTI)

    Morales, J. P.; Taylor, P. R.; Bell, R. E.; Chan, Y. C. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Vascular Surgery (United Kingdom); Sabharwal, T. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Interventional Radiology (United Kingdom); Carrell, T. W. G. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Vascular Surgery (United Kingdom); Reidy, J. F. [Guy's and St. Thomas' Foundation Hospital NHS Trust, Department of Interventional Radiology (United Kingdom)], E-mail: John.Reidy@gstt.nhs.uk

    2007-09-15T23:59:59.000Z

    Open surgery for thoracic aortic disease is associated with significant morbidity and the reported rates for paraplegia and stroke are 3%-19% and 6%-11%, respectively. Spinal cord ischemia and stroke have also been reported following endoluminal repair. This study reviews the incidence of paraplegia and stroke in a series of 186 patients treated with thoracic stent grafts. From July 1997 to September 2006, 186 patients (125 men) underwent endoluminal repair of thoracic aortic pathology. Mean age was 71 years (range, 17-90 years). One hundred twenty-eight patients were treated electively and 58 patients had urgent procedures. Anesthesia was epidural in 131, general in 50, and local in 5 patients. Seven patients developed paraplegia (3.8%; two urgent and five elective). All occurred in-hospital apart from one associated with severe hypotension after a myocardial infarction at 3 weeks. Four of these recovered with cerebrospinal fluid (CSF) drainage. One patient with paraplegia died and two had permanent neurological deficit. The rate of permanent paraplegia and death was 1.6%. There were seven strokes (3.8%; four urgent and three elective). Three patients made a complete recovery, one had permanent expressive dysphasia, and three died. The rate of permanent stroke and death was 2.1%. Endoluminal treatment of thoracic aortic disease is an attractive alternative to open surgery; however, there is still a risk of paraplegia and stroke. Permanent neurological deficits and death occurred in 3.7% of the patients in this series. We conclude that prompt recognition of paraplegia and immediate insertion of a CSF drain can be an effective way of recovering spinal cord function and improving the prognosis.

  8. Development and validation of bonded composite doubler repairs for commercial aircraft.

    SciTech Connect (OSTI)

    Roach, Dennis Patrick; Rackow, Kirk A.

    2007-07-01T23:59:59.000Z

    A typical aircraft can experience over 2,000 fatigue cycles (cabin pressurizations) and even greater flight hours in a single year. An unavoidable by-product of aircraft use is that crack, impact, and corrosion flaws develop throughout the aircraft's skin and substructure elements. Economic barriers to the purchase of new aircraft have placed even greater demands on efficient and safe repair methods. The use of bonded composite doublers offers the airframe manufacturers and aircraft maintenance facilities a cost effective method to safely extend the lives of their aircraft. Instead of riveting multiple steel or aluminum plates to facilitate an aircraft repair, it is now possible to bond a single Boron-Epoxy composite doubler to the damaged structure. The FAA's Airworthiness Assurance Center at Sandia National Labs (AANC), Boeing, and Federal Express completed a pilot program to validate and introduce composite doubler repair technology to the U.S. commercial aircraft industry. This project focused on repair of DC-10 fuselage structure and its primary goal was to demonstrate routine use of this repair technology using niche applications that streamline the design-to-installation process. As composite doubler repairs gradually appear in the commercial aircraft arena, successful flight operation data is being accumulated. These commercial aircraft repairs are not only demonstrating the engineering and economic advantages of composite doubler technology but they are also establishing the ability of commercial maintenance depots to safely adopt this repair technique. This report presents the array of engineering activities that were completed in order to make this technology available for widespread commercial aircraft use. Focused laboratory testing was conducted to compliment the field data and to address specific issues regarding damage tolerance and flaw growth in composite doubler repairs. Fatigue and strength tests were performed on a simulated wing repair using a substandard design and a flawed installation. In addition, the new Sol-Gel surface preparation technique was evaluated. Fatigue coupon tests produced Sol-Gel results that could be compared with a large performance database from conventional, riveted repairs. It was demonstrated that not only can composite doublers perform well in severe off-design conditions (low doubler stiffness and presence of defects in doubler installation) but that the Sol-Gel surface preparation technique is easier and quicker to carry out while still producing optimum bonding properties. Nondestructive inspection (NDI) methods were developed so that the potential for disbond and delamination growth could be monitored and crack growth mitigation could be quantified. The NDI methods were validated using full-scale test articles and the FedEx aircraft installations. It was demonstrated that specialized NDI techniques can detect flaws in composite doubler installations before they reach critical size. Probability of Detection studies were integrated into the FedEx training in order to quantify the ability of aircraft maintenance depots to properly monitor these repairs. In addition, Boeing Structural Repair and Nondestructive Testing Manuals were modified to include composite doubler repair and inspection procedures. This report presents the results from the FedEx Pilot Program that involved installation and surveillance of numerous repairs on operating aircraft. Results from critical NDI evaluations are reported in light of damage tolerance assessments for bonded composite doublers. This work has produced significant interest from airlines and aircraft manufacturers. The successful Pilot Program produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. This report discusses both the laboratory data and Pilot Program results from repair installations on operating aircraft to introduce composite doubler repairs into mainstream commercial aircraft use.

  9. Effect of multiple repairs in girth welds of pipelines on the mechanical properties

    SciTech Connect (OSTI)

    Vega, O.E.; Hallen, J.M. [Departamento de Ingenieria Metalurgica, ESIQIE-IPN, Laboratorios Pesados de Metalurgia, UPALM, Zacatenco, C.P. 07738, Mexico D.F. (Mexico); Villagomez, A. [Construcciones Maritimas Mexicanas, CMM-PROTEXA, Av. Periferica s/n, Fracc. Lomas de Holche, C.P. 24120, Cd. del Carmen, Campeche (Mexico); Contreras, A. [Instituto Mexicano del Petroleo, Investigacion en Ductos, Corrosion y Materiales, Eje Central Lazaro Cardenas Norte 152 Col. San Bartolo Atepehuacan, C.P. 07730, Mexico D.F. (Mexico)], E-mail: acontrer@imp.mx

    2008-10-15T23:59:59.000Z

    This work presents the results of multiple weld repairs in the same area in seamless API X-52 microalloyed steel pipe. Four conditions of shielded metal arc welding repairs and one as-welded specimen of the girth weld were characterized to determine changes in the microstructure, grain size in the heat affected zone, and to evaluate their effect on the mechanical properties of the weld joints. The mechanical properties by means of tension tests, Charpy-V impact resistance and Vickers hardness of the welds were analyzed. The results indicate that significant changes are not generated in the microstructural constituents of the heat affected zone. Grain growth in the heat affected zone at the specimen mid-thickness with the number of repairs was observed. Tensile strength of the weld joints meets the requirement of the API 1104 standard even after the fourth weld repair. Significant reduction in Charpy-V impact resistance with the number of weld repairs was found when the notch location was in the intersection of the fusion line with the specimen mid-thickness. A significant increase in the Vickers hardness of the heat affected zone occurred after the first repair and a gradual decrease in the Vickers hardness occurred as the number of repairs increases.

  10. Fabrication Flaw Density and Distribution In Repairs to Reactor Pressure Vessel and Piping Welds

    SciTech Connect (OSTI)

    GJ Schuster, FA Simonen, SR Doctor

    2008-04-01T23:59:59.000Z

    The Pacific Northwest National Laboratory is developing a generalized fabrication flaw distribution for the population of nuclear reactor pressure vessels and for piping welds in U.S. operating reactors. The purpose of the generalized flaw distribution is to predict component-specific flaw densities. The estimates of fabrication flaws are intended for use in fracture mechanics structural integrity assessments. Structural integrity assessments, such as estimating the frequency of loss-of-coolant accidents, are performed by computer codes that require, as input, accurate estimates of flaw densities. Welds from four different reactor pressure vessels and a collection of archived pipes have been studied to develop empirical estimates of fabrication flaw densities. This report describes the fabrication flaw distribution and characterization in the repair weld metal of vessels and piping. This work indicates that large flaws occur in these repairs. These results show that repair flaws are complex in composition and sometimes include cracks on the ends of the repair cavities. Parametric analysis using an exponential fit is performed on the data. The relevance of construction records is established for describing fabrication processes and product forms. An analysis of these records shows there was a significant change in repair frequency over the years when these components were fabricated. A description of repair flaw morphology is provided with a discussion of fracture mechanics significance. Fabrication flaws in repairs are characterized using optimized-access, high-sensitivity nondestructive ultrasonic testing. Flaw characterizations are then validated by other nondestructive evaluation techniques and complemented by destructive testing.

  11. DNA Repair Alterations in Children With Pediatric Malignancies: Novel Opportunities to Identify Patients at Risk for High-Grade Toxicities

    SciTech Connect (OSTI)

    Ruebe, Claudia E., E-mail: claudia.ruebe@uks.e [Department of Radiation Oncology, Saarland University, Homburg/Saar (Germany); Fricke, Andreas; Schneider, Ruth; Simon, Karin; Kuehne, Martin; Fleckenstein, Jochen [Department of Radiation Oncology, Saarland University, Homburg/Saar (Germany); Graeber, Stefan [Institute of Medical Biometrics, Epidemiology and Medical Informatics, Saarland University, Homburg/Saar (Germany); Graf, Norbert [Department of Pediatric Hematology and Oncology, Saarland University, Homburg/Saar (Germany); Ruebe, Christian [Department of Radiation Oncology, Saarland University, Homburg/Saar (Germany)

    2010-10-01T23:59:59.000Z

    Purpose: To evaluate, in a pilot study, the phosphorylated H2AX ({gamma}H2AX) foci approach for identifying patients with double-strand break (DSB) repair deficiencies, who may overreact to DNA-damaging cancer therapy. Methods and Materials: The DSB repair capacity of children with solid cancers was analyzed compared with that of age-matched control children and correlated with treatment-related normal-tissue responses (n = 47). Double-strand break repair was investigated by counting {gamma}H2AX foci in blood lymphocytes at defined time points after irradiation of blood samples. Results: Whereas all healthy control children exhibited proficient DSB repair, 3 children with tumors revealed clearly impaired DSB repair capacities, and 2 of these repair-deficient children developed life-threatening or even lethal normal-tissue toxicities. The underlying mutations affecting regulatory factors involved in DNA repair pathways were identified. Moreover, significant differences in mean DSB repair capacity were observed between children with tumors and control children, suggesting that childhood cancer is based on genetic alterations affecting DSB repair function. Conclusions: Double-strand break repair alteration in children may predispose to cancer formation and may affect children's susceptibility to normal-tissue toxicities. Phosphorylated H2AX analysis of blood samples allows one to detect DSB repair deficiencies and thus enables identification of children at risk for high-grade toxicities.

  12. CtIP tetramer assembly is required for DNA-end resection and repair

    E-Print Network [OSTI]

    Davies, Owen R.; Forment, Josep V.; Sun, Meidai; Belotserkovskaya, Rimma; Coates, Julia; Galanty, Yaron; Demir, Mukerrem; Morton, Christopher; Rzechorzek, Neil; Jackson, Stephen P.; Pellegrini, Luca

    2015-01-05T23:59:59.000Z

    1     CtIP tetramer assembly is required for DNA-end resection and repair Owen R. Davies1,4*, Josep V. Forment1,2,3*, Meidai Sun1, Rimma Belotserkovskaya1,2, Julia Coates1,2, Yaron Galanty1,2, Mukerrem Demir1,2, Christopher Morton1... that a CtIP tetramer architecture is essential for effective DSB repair by homologous recombination. Keywords CtIP/RBBP8, double-strand DNA break repair, DNA-end resection, gene conversion, homologous recombination. 3...

  13. Development of Baseline Monthly Utility Models, Stabilization of Data Logging Environment and Development of Metering Plan and Shopping List for Fort Hood, Texas

    E-Print Network [OSTI]

    Saman, N. F.; Reddy, T. A.; Haberl, J. S.; Claridge, D. E.; Turner, W. D.

    1995-01-01T23:59:59.000Z

    sensors) at *ue west substation, and the installation of the ESL's Monitor software for use by the Energy Office at the base. The objective of Task C is to provide a metering plan and shopping list of necessary data points to provide CERL with energy... and EModel, and it was found that EModel gave more accurate modeling results than PRISM, and therefore EModel was used in the analysis. For Task B, a weather station that includes temperature, humidity and solar sensors was installed at the west substation...

  14. Saving Ovid Search Strategies and Creating AutoAlerts Ovid's Save Search/Alert function allows you to store search strategies

    E-Print Network [OSTI]

    Myers, Lawrence C.

    Saving Ovid Search Strategies and Creating AutoAlerts Ovid's Save Search/Alert function allows you having to retype each search set manually. It also allows you to save a strategy to be re. * Click here for a guide to the Save Search/Alert function. Personal Accounts are needed to save searches

  15. L'analyse de l'activit infirmire : ses effets sur l'auto-efficacit collective de cadres formateurs confronts au changement

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    d'une recherche-action conduite dans cinq instituts de formation en soins infirmiers, auprès de cent neuf formateurs. Anticipant la réforme 2009 de la formation en soins infirmiers, cette recherche professionnelle, auto-efficacité collective, évaluation des compétences, formation en soins infirmiers, compétence

  16. ALTERNATIVE FUEL VEHICLE (AFV) INFORMATION Over 98% of the U-M auto passenger fleet is flex fuel vehicles (FFV). A FFV is capable of operating on

    E-Print Network [OSTI]

    Kirschner, Denise

    ALTERNATIVE FUEL VEHICLE (AFV) INFORMATION Over 98% of the U-M auto passenger fleet is flex fuel of both. FFV's are equipped with an engine and fuel system designed specifically to be compatible with ethanol's chemical properties. FFV's qualify as alternative fuel vehicles under the Energy Policy Act

  17. Advanced emission-speciation methodologies for the Auto/Oil Air Quality Improvement Research Program. 1. Hydrocarbons and ethers

    SciTech Connect (OSTI)

    Jensen, T.E.; Siegl, W.O.; Lipari, F.; Loo, J.F.; Sigsby, J.E.

    1992-01-01T23:59:59.000Z

    An analytical method for the determination of hydrocarbon and ether emissions from gasoline-, methanol-, and flexible-fueled vehicles is described. This method was used in Phase I of the Auto/Oil Air Quality Improvement Research Program to provide emissions data for various vehicles using individual reformulated gasolines and alternate fuels. These data would then be used for air modeling studies. Emission samples for tailpipe, evaporative, and running loss were collected in Tedlar bags. Gas chromatographic analysis of the emissions samples included 140 components (hydrocarbons, ethers, alcohols and aldehydes) between C1 and C12 in a single analysis of 54-minutes duration. Standardization, quality control procedures, and inter-laboratory comparisons developed and completed as part of this program are also described. (Copyright (c) 1992 Society of Automotive Engineers, Inc.).

  18. A New Multi-Gaussian Auto-Correlation Function for the Modeling of Realistic Shot Peened Random Rough Surfaces

    SciTech Connect (OSTI)

    Hassan, W. [Honeywell Aerospace, 111 S. 34th Street, M/S 503-118 Phoenix, AZ 85034 (United States); Blodgett, M. [Air Force Research Laboratory (AFRL/MLLP), 2230 10th Street, Suite 1, Dayton, OH 45433 (United States)

    2006-03-06T23:59:59.000Z

    Shot peening is the primary surface treatment used to create a uniform, consistent, and reliable sub-surface compressive residual stress layer in aero engine components. A by-product of the shot peening process is random surface roughness that can affect the measurements of the resulting residual stresses and therefore impede their NDE assessment. High frequency eddy current conductivity measurements have the potential to assess these residual stresses in Ni-base super alloys. However, the effect of random surface roughness is expected to become significant in the desired measurement frequency range of 10 to 100 MHz. In this paper, a new Multi-Gaussian (MG) auto-correlation function is proposed for modeling the resulting pseudo-random rough profiles. Its use in the calculation of the Apparent Eddy Current Conductivity (AECC) loss due to surface roughness is demonstrated. The numerical results presented need to be validated with experimental measurements.

  19. Auto-Calibration and Control Strategy Determination for a Variable-Speed Heat Pump Water Heater Using Optimization

    SciTech Connect (OSTI)

    Shen, Bo [ORNL] [ORNL; Abdelaziz, Omar [ORNL] [ORNL; Rice, C Keith [ORNL] [ORNL

    2012-01-01T23:59:59.000Z

    This paper introduces applications of the GenOpt optimizer coupled with a vapor compression system model for auto-calibration and control strategy determination towards the development of a variable-speed ground-source heat pump water heating unit. The GenOpt optimizer can be linked with any simulation program using input and output text files. It effectively facilitates optimization runs. Using our GenOpt wrapper program, we can flexibly define objectives for optimizations, targets, and constraints. Those functionalities enable running extensive optimization cases for model calibration, configuration design and control strategy determination. In addition, we describe a methodology to improve prediction accuracy using functional calibration curves. Using the calibrated model, we investigated control strategies of the ground-source heat pump water heater, considering multiple control objectives, covering the entire operation range.

  20. Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard

    SciTech Connect (OSTI)

    Terwilliger, Thomas C., E-mail: terwilliger@lanl.gov [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Adams, Paul D. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720 (United States); Read, Randy J.; McCoy, Airlie J. [Department of Haematology, University of Cambridge, Cambridge CB2 0XY (United Kingdom); Moriarty, Nigel W.; Grosse-Kunstleve, Ralf W.; Afonine, Pavel V.; Zwart, Peter H. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720 (United States); Hung, Li-Wei [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2009-06-01T23:59:59.000Z

    Ten measures of experimental electron-density-map quality are examined and the skewness of electron density is found to be the best indicator of actual map quality. A Bayesian approach to estimating map quality is developed and used in the PHENIX AutoSol wizard to make decisions during automated structure solution. Estimates of the quality of experimental maps are important in many stages of structure determination of macromolecules. Map quality is defined here as the correlation between a map and the corresponding map obtained using phases from the final refined model. Here, ten different measures of experimental map quality were examined using a set of 1359 maps calculated by re-analysis of 246 solved MAD, SAD and MIR data sets. A simple Bayesian approach to estimation of map quality from one or more measures is presented. It was found that a Bayesian estimator based on the skewness of the density values in an electron-density map is the most accurate of the ten individual Bayesian estimators of map quality examined, with a correlation between estimated and actual map quality of 0.90. A combination of the skewness of electron density with the local correlation of r.m.s. density gives a further improvement in estimating map quality, with an overall correlation coefficient of 0.92. The PHENIX AutoSol wizard carries out automated structure solution based on any combination of SAD, MAD, SIR or MIR data sets. The wizard is based on tools from the PHENIX package and uses the Bayesian estimates of map quality described here to choose the highest quality solutions after experimental phasing.

  1. Functional Characterization of Kansl2 and Its Role in Mitochondrial DNA Repair and Maintenance

    E-Print Network [OSTI]

    Liau, Wei-Siang

    2012-01-01T23:59:59.000Z

    understanding of the maintenance and repair of the mtDNA,A is necessary for mtDNA maintenance and embryogenesis in1997). Mitochondrial DNA maintenance in vertebrates. Annu

  2. GENETIC AND MOLECULAR ANALYSIS OF DNA DAMAGE REPAIR AND TOLERANCE PATHWAYS.

    SciTech Connect (OSTI)

    SUTHERLAND, B.M.

    2001-07-26T23:59:59.000Z

    Radiation can damage cellular components, including DNA. Organisms have developed a panoply of means of dealing with DNA damage. Some repair paths have rather narrow substrate specificity (e.g. photolyases), which act on specific pyrimidine photoproducts in a specific type (e.g., DNA) and conformation (double-stranded B conformation) of nucleic acid. Others, for example, nucleotide excision repair, deal with larger classes of damages, in this case bulky adducts in DNA. A detailed discussion of DNA repair mechanisms is beyond the scope of this article, but one can be found in the excellent book of Friedberg et al. [1] for further detail. However, some DNA damages and paths for repair of those damages important for photobiology will be outlined below as a basis for the specific examples of genetic and molecular analysis that will be presented below.

  3. Plug repairs of marine glass fiber / vinyl ester laminates subjected to uniaxial tension

    E-Print Network [OSTI]

    Michelis, Alexandros

    2009-01-01T23:59:59.000Z

    Glass fiber/vinyl ester composite laminates are currently being used and proposed for the hulls, bulkheads, and superstructures of large ships. This thesis examines the effectiveness of the repair of such laminates using ...

  4. Review of Maintenance and Repair Times for Components in Technological Facilities

    SciTech Connect (OSTI)

    L. C. Cadwallader

    2012-11-01T23:59:59.000Z

    This report is a compilation of some unique component repair time data and it also presents citations of more extensive reports where lists of repair times can be found. This collection of information should support analysts who seek to quantify maintainability and availability of high technology and nuclear energy production systems. While there are newer sources of repair time information, most, if not all, of the newer sources are proprietary and cannot be shared. This report offers data that, while older, is openly accessible and can serve as reasonable estimates of repair times, at least for initial studies. Some times were found for maintenance times in radiation environments, and some guidance for multiplicative factors to use to account for work in contamination areas.

  5. Modeling and centralization of strategic inventory for repairable and long lead-time spare parts

    E-Print Network [OSTI]

    Duncan, Tyeliah Elaine

    2011-01-01T23:59:59.000Z

    This thesis develops an optimal inventory model for repairable and long leadtime spare parts for an Engine overhaul business. In addition, it presents a business case for centralization of inventory. Pratt & Whitney purchased ...

  6. Emerging Trends in Heart Valve Engineering: Part III. Novel Technologies for Mitral Valve Repair and Replacement

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    and J. D. Puskas. Mitral-valve repair versus replacement forbioprosthetic heart valves. Ann. Thorac. Surg. 71:S417–mechanics of arti?cial heart valves. Clin. Exp. Pharmacol.

  7. Tiny Terminators: New Micro-Robots Assemble, Repair Themselves and Are Surprisingly Strong

    Broader source: Energy.gov [DOE]

    Tiny robots that can assemble and repair themselves? Watch a video of Argonne National Laboratory's micro-robots that easily perform tasks that can challenge other robots, including moving objects that are larger than themselves.

  8. Consistency Management with Repair Actions Christian Nentwich, Wolfgang Emmerich and Anthony Finkelstein

    E-Print Network [OSTI]

    van der Hoek, André

    Consistency Management with Repair Actions Christian Nentwich, Wolfgang Emmerich and Anthony Finkelstein Department of Computer Science University College London Gower Street, London WC1E 6BT, UK {c.nentwich,w.emmerich

  9. Use of CFRP Overlays to Repair Fatigue Damage in Steel Bridge Girders and Components

    E-Print Network [OSTI]

    Gangel, Regan Elisabeth

    2012-05-31T23:59:59.000Z

    Fatigue damage in steel girder bridges built prior to the mid-1980s is common due to distortion-induced fatigue. Different repair techniques have been developed and implemented to retrofit bridges of this era with existing fatigue damage...

  10. Community-Minded Interns at Savannah River Site Help Area Residents in Need with Home Repairs

    Broader source: Energy.gov [DOE]

    AIKEN, S.C. – More than two dozen college interns who worked at the Savannah River Site (SRS) this summer joined other volunteers and headed into area neighborhoods to help people in need with home repairs.

  11. RESTORING A DAMAGED 16-YEAR -OLD INSULATING POLYMER CONCRETE DIKE OVERLAY: REPAIR MATERIALS AND TECHNOLOGIES.

    SciTech Connect (OSTI)

    SUGAMA,T.

    2007-01-01T23:59:59.000Z

    The objective of this program was to design and formulate organic polymer-based material systems suitable for repairing and restoring the overlay panels of insulating lightweight polymer concrete (ILPC) from the concrete floor and slope wall of a dike at KeySpan liquefied natural gas (LNG) facility in Greenpoint, Brooklyn, NY, just over sixteen years ago. It also included undertaking a small-scale field demonstration to ensure that the commercial repairing technologies were applicable to the designed and formulated materials.

  12. Endovascular Abdominal Aortic Aneurysm Repair in the Presence of a Kidney Transplant: Therapeutic Considerations

    SciTech Connect (OSTI)

    Karkos, Christos D., E-mail: ckarkos@hotmail.com; McMahon, Greg [Leicester Royal Infirmary, Department of Vascular and Endovascular Surgery (United Kingdom); Fishwick, Guy [Leicester Royal Infirmary, Department of Radiology (United Kingdom); Lambert, Kelly; Bagga, Ajay; McCarthy, Mark J. [Leicester Royal Infirmary, Department of Vascular and Endovascular Surgery (United Kingdom)

    2006-04-15T23:59:59.000Z

    Abdominal aortic aneurysm (AAA) repair in the presence of a kidney transplant can be extremely challenging, as it carries significant risks of renal ischemia. Endovascular repair is an attractive option, as it can be performed with little or no impairment of renal arterial flow. We describe the endovascular management of a recurrent AAA in a patient with a functioning renal transplant using a custom-made aorto-uni-iliac device. We discuss the planning and the potential problems of the technique.

  13. In situ repair of a failed compression fitting

    DOE Patents [OSTI]

    Wolbert, R.R.; Jandrasits, W.G.

    1985-08-05T23:59:59.000Z

    A method and apparatus for the in situ repair of a failed compression fitting is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  14. In situ repair of a failed compression fitting

    DOE Patents [OSTI]

    Wolbert, Ronald R. (McKees Rocks, PA); Jandrasits, Walter G. (Pittsburgh, PA)

    1986-01-01T23:59:59.000Z

    A method and apparatus for the in situ repair of a failed compression fitg is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  15. Remote Welding, NDE and Repair of DOE Standardized Canisters

    SciTech Connect (OSTI)

    Eric Larsen; Art Watkins; Timothy R. McJunkin; Dave Pace; Rodney Bitsoi

    2006-05-01T23:59:59.000Z

    The U.S. Department of Energy (DOE) created the National Spent Nuclear Fuel Program (NSNFP) to manage DOE’s spent nuclear fuel (SNF). One of the NSNFP’s tasks is to prepare spent nuclear fuel for storage, transportation, and disposal at the national repository. As part of this effort, the NSNFP developed a standardized canister for interim storage and transportation of SNF. These canisters will be built and sealed to American Society of Mechanical Engineers (ASME) Section III, Division 3 requirements. Packaging SNF usually is a three-step process: canister loading, closure welding, and closure weld verification. After loading SNF into the canisters, the canisters must be seal welded and the welds verified using a combination of visual, surface eddy current, and ultrasonic inspection or examination techniques. If unacceptable defects in the weld are detected, the defective sections of weld must be removed, re-welded, and re-inspected. Due to the high contamination and/or radiation fields involved with this process, all of these functions must be performed remotely in a hot cell. The prototype apparatus to perform these functions is a floor-mounted carousel that encircles the loaded canister; three stations perform the functions of welding, inspecting, and repairing the seal welds. A welding operator monitors and controls these functions remotely via a workstation located outside the hot cell. The discussion describes the hardware and software that have been developed and the results of testing that has been done to date.

  16. INTERNAL REPAIR OF GAS PIPLINES SURVEY OF OPERATOR EXPERIENCE AND INDUSTRY NEEDS REPORT

    SciTech Connect (OSTI)

    Ian D. Harris

    2003-09-01T23:59:59.000Z

    A repair method that can be applied from the inside of a gas transmission pipeline (i.e., a trenchless repair) is an attractive alternative to conventional repair methods since the need to excavate the pipeline is precluded. This is particularly true for pipelines in environmentally sensitive and highly populated areas. The objectives of the project are to evaluate, develop, demonstrate, and validate internal repair methods for pipelines; develop a functional specification for an internal pipeline repair system; and prepare a recommended practice for internal repair of pipelines. The purpose of this survey is to better understand the needs and performance requirements of the natural gas transmission industry regarding internal repair. A total of fifty-six surveys were sent to pipeline operators. A total of twenty completed surveys were returned, representing a 36% response rate, which is considered very good given the fact that tailored surveys are known in the marketing industry to seldom attract more than a 10% response rate. The twenty survey responses produced the following principal conclusions: (1) Use of internal weld repair is most attractive for river crossings, under other bodies of water (e.g., lakes and swamps) in difficult soil conditions, under highways, under congested intersections, and under railway crossings. All these areas tend to be very difficult and very costly if, and where, conventional excavated repairs may be currently used. (2) Internal pipe repair offers a strong potential advantage to the high cost of horizontal direct drilling (HDD) when a new bore must be created to solve a leak or other problem in a water/river crossing. (3) The typical travel distances required can be divided into three distinct groups: up to 305 m (1,000 ft.); between 305 m and 610 m (1,000 ft. and 2,000 ft.); and beyond 914 m (3,000 ft.). In concept, these groups require pig-based systems; despooled umbilical systems could be considered for the first two groups. For the last group a self-propelled system with an onboard self-contained power and welding system is required. (4) Pipe size range requirements range from 50.8 mm (2 in.) through 1,219.2 mm (48 in.) in diameter. The most common size range for 80% to 90% of operators surveyed is 508 mm to 762 mm (20 in. to 30 in.) diameter, with 95% using 558.8 mm (22 in.) diameter pipe.

  17. Development of bonded composite doublers for the repair of oil recovery equipment.

    SciTech Connect (OSTI)

    Roach, David W.; Rackow, Kirk A.

    2005-06-01T23:59:59.000Z

    An unavoidable by-product of a metallic structure's use is the appearance of crack and corrosion flaws. Economic barriers to the replacement of these structures have created an aging infrastructure and placed even greater demands on efficient and safe repair methods. In the past decade, an advanced composite repair technology has made great strides in commercial aviation use. Extensive testing and analysis, through joint programs between the Sandia Labs FAA Airworthiness Assurance Center and the aviation industry, have proven that composite materials can be used to repair damaged aluminum structure. Successful pilot programs have produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. With this foundation in place, this effort is adapting bonded composite repair technology to civil structures. The use of bonded composite doublers has the potential to correct the difficulties associated with current repair techniques and the ability to be applied where there are no rehabilitation options. It promises to be cost-effective with minimal disruption to the users of the structure. This report concludes a study into the application of composite patches on thick steel structures typically used in mining operations. Extreme fatigue, temperature, erosive, and corrosive environments induce an array of equipment damage. The current weld repair techniques for these structures provide a fatigue life that is inferior to that of the original plate. Subsequent cracking must be revisited on a regular basis. The use of composite doublers, which do not have brittle fracture problems such as those inherent in welds, can help extend the structure's fatigue life and reduce the equipment downtime. Two of the main issues for adapting aircraft composite repairs to civil applications are developing an installation technique for carbon steel and accommodating large repairs on extremely thick structures. This study developed and proved an optimum field installation process using specific mechanical and chemical surface preparation techniques coupled with unique, in-situ heating methods. In addition, a comprehensive performance assessment of composite doubler repairs was completed to establish the viability of this technology for large, steel structures. The factors influencing the durability of composite patches in severe field environments were evaluated along with related laminate design issues.

  18. TRANSPORT...18 SHOPPING...22

    E-Print Network [OSTI]

    Brierley, Andrew

    of renewable energy sources, paying attention to the environmental impact of our activities, and setting, while changes are made here on the ground through campaigns around transport, food and ethical targets for the reduction of energy consumption, and the attainment of carbon neutrality. I am delighted

  19. Relocation and repair of the National Geotechnical Centrifuge. Final report

    SciTech Connect (OSTI)

    Cheney, J.A. [California Univ., Davis, CA (United States). Center for Geotechnical Modeling

    1994-10-01T23:59:59.000Z

    In January of 1984, the large geotechnical centrifuge located at NASA Ames Research Center, was in the first stages of operational checkout when the main thrust bearing of the large D.C. drive motor failed. After many months of investigation and proposals for repair of the facility, it became evident that it would be far more advantageous to the engineering community to remove those components of the centrifuge that were undamaged to the Davis campus and replace the drive system completely. The large centrifuge had cost over 2 million dollars to build, and it would have been irresponsible to simply scrap it. Recognizing this fact, funds were solicited and received from various sources, and Beam Engineering Inc. was contracted to design and construct the centrifuge at its new location. The University of California contributed a quarter of a million dollars and Tyndall Air Force Base, through Los Alamos National Laboratory, contributed $140,000. There were funds also contributed by LANL, LLNL, US Navy and NSF. The first stage in the phased development of the newly located centrifuge is nearing completion, which prompts the writing of this report. By the time that this report reaches the reader the first runs of the centrifuge will have been completed. The present report describes the present capability of the centrifuge and the plans for upgrading as time goes on. Several pilot studies were carried out. The experiments involved (1) the effects of nearby explosions on buried thin walled containers and (2) the advection and dispersion of toxic waste water through soils.

  20. WHERE MULTIFUNCTIONAL DNA REPAIR PROTEINS MEET: MAPPING THE INTERACTION DOMAINS BETWEEN XPG AND WRN

    SciTech Connect (OSTI)

    Rangaraj, K.; Cooper, P.K.; Trego, K.S.

    2009-01-01T23:59:59.000Z

    The rapid recognition and repair of DNA damage is essential for the maintenance of genomic integrity and cellular survival. Multiple complex and interconnected DNA damage responses exist within cells to preserve the human genome, and these repair pathways are carried out by a specifi c interplay of protein-protein interactions. Thus a failure in the coordination of these processes, perhaps brought about by a breakdown in any one multifunctional repair protein, can lead to genomic instability, developmental and immunological abnormalities, cancer and premature aging. This study demonstrates a novel interaction between two such repair proteins, Xeroderma pigmentosum group G protein (XPG) and Werner syndrome helicase (WRN), that are both highly pleiotropic and associated with inherited genetic disorders when mutated. XPG is a structure-specifi c endonuclease required for the repair of UV-damaged DNA by nucleotide excision repair (NER), and mutations in XPG result in the diseases Xeroderma pigmentosum (XP) and Cockayne syndrome (CS). A loss of XPG incision activity results in XP, whereas a loss of non-enzymatic function(s) of XPG causes CS. WRN is a multifunctional protein involved in double-strand break repair (DSBR), and consists of 3’–5’ DNA-dependent helicase, 3’–5’ exonuclease, and single-strand DNA annealing activities. Nonfunctional WRN protein leads to Werner syndrome, a premature aging disorder with increased cancer incidence. Far Western analysis was used to map the interacting domains between XPG and WRN by denaturing gel electrophoresis, which separated purifi ed full length and recombinant XPG and WRN deletion constructs, based primarily upon the length of each polypeptide. Specifi c interacting domains were visualized when probed with the secondary protein of interest which was then detected by traditional Western analysis using the antibody of the secondary protein. The interaction between XPG and WRN was mapped to the C-terminal region of XPG as well as the C-terminal region of WRN. The physical interaction between XPG and WRN links NER, (made evident by the disease XP) with DSBR, which imparts additional knowledge of the overlapping nature of these two proteins and the previously distinct DNA repair pathways they are associated with. Since genomic integrity is constantly threatened by both endogenous and exogenous (internal and external) damage, understanding the roles of these proteins in coordinating DNA repair processes with replication will signifi cantly further understanding how defects instigate physiological consequences in response to various DNA damaging sources. This ultimately contributes to our understanding of cancer and premature aging.

  1. Doppler effect and Hubble effect in different models of space-time in the case of auto-parallel motion of the observer

    E-Print Network [OSTI]

    Sawa Manoff

    2004-01-04T23:59:59.000Z

    Doppler effect and Hubble effect in different models of space-time in the case of auto-parallel motion of the observer are considered. The Doppler effect and shift frequency parameter are specialized for the case of auto-parallel motion of the observer. The Hubble effect and shift frequency parameter are considered for the same case. It is shown that by the use of the variation of the shift frequency parameter during a time perod, considered locally in the proper frame of reference of an observer, one can directly determine the centrifugal (centripetal) relative velocity and acceleration as well as the Coriolis relative velocity and acceleration of an astronomical object moving relatively to the observer. All results are obtained on purely kinematic basis without taking into account the dynamic reasons for the considered effect. PACS numbers: 98.80.Jk; 98.62.Py; 04.90.+e; 04.80.Cc

  2. HANFORD SITE LOW EXPOSURE PIPELINE REPAIR USING A NON-METALLIC COMPOSITE SYSTEM

    SciTech Connect (OSTI)

    HUTH RJ

    2009-11-12T23:59:59.000Z

    At the Department of Energy, Richland Operations (DOE-RL) Hanford site in eastern Washington, a 350 mm (14 inch) diameter high density polyethylene (HDPE) pump recirculation pipeline failed at a bonded joint adjacent to a radiologically and chemically contaminated groundwater storage basin. The responsible DOE-RL contractor, CH2MHill Plateau Remediation Company, applied a fiberglass reinforced plastic (composite) field repair system to the failed joint. The system was devised specifically for the HDPE pipe repair at the Hanford site, and had not been used on this type of plastic piping previously. This paper introduces the pipe failure scenario, describes the options considered for repair and discusses the ultimate resolution of the problem. The failed pipeline was successfully returned to service with minimal impact on waste water treatment plant operating capacity. Additionally, radiological and chemical exposures to facility personnel were maintained as low as reasonably achievable (ALARA). The repair is considered a success for the near term, and future monitoring will prove whether the repair can be considered for long term service and as a viable alternative for similar piping failures at the Hanford site.

  3. A high dimensional delay selection for the reconstruction of proper Phase Space with Cross auto-correlation

    E-Print Network [OSTI]

    Sanjay Kumar Palit; Sayan Mukherjee; D. K. Bhattacharya

    2014-09-21T23:59:59.000Z

    For the purpose of phase space reconstruction from nonlinear time series, delay selection is one of the most vital criteria. This is normally done by using a general measure viz., mutual information (MI). However, in that case, the delay selection is limited to the estimation of a single delay using MI between two variables only. The corresponding reconstructed phase space is also not satisfactory. To overcome the situation, a high-dimensional estimator of the MI is used; it selects more than one delay between more than two variables. The quality of the reconstructed phase space is tested by shape distortion parameter (SD), it is found that even this multidimensional MI sometimes fails to produce a less distorted phase space. In this paper, an alternative nonlinear measure cross autocorrelation (CAC) is introduced. A comparative study is made between the reconstructed phase spaces of a known three dimensional Neuro dynamical model, Lorenz dynamical model and a three dimensional food web model under MI for two and higher dimensions and also under cross auto-correlation separately. It is found that the least distorted phase space is obtained only under the notion of cross autocorrelation.

  4. Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence

    SciTech Connect (OSTI)

    Yuan, Ping; Paterson, Reay G.; Leser, George P.; Lamb, Robert A.; Jardetzky, Theodore S. (Stanford-MED); (NWU)

    2012-09-06T23:59:59.000Z

    Paramyxovirus hemagglutinin-neuraminidase (HN) plays roles in viral entry and maturation, including binding to sialic acid receptors, activation of the F protein to drive membrane fusion, and enabling virion release during virus budding. HN can thereby directly influence virulence and in a subset of avirulent Newcastle disease virus (NDV) strains, such as NDV Ulster, HN must be proteolytically activated to remove a C-terminal extension not found in other NDV HN proteins. Ulster HN is 616 amino acids long and the 45 amino acid C-terminal extension present in its precursor (HN0) form has to be cleaved to render HN biologically active. Here we show that Ulster HN contains an inter-subunit disulfide bond within the C-terminal extension at residue 596, which regulates HN activities and neuraminidase (NA) domain dimerization. We determined the crystal structure of the dimerized NA domain containing the C-terminal extension, which extends along the outside of the sialidase {beta}-propeller domain and inserts C-terminal residues into the NA domain active site. The C-terminal extension also engages a secondary sialic acid binding site present in NDV HN proteins, which is located at the NA domain dimer interface, that most likely blocks its attachment function. These results clarify how the Ulster HN C-terminal residues lead to an auto-inhibited state of HN, the requirement for proteolytic activation of HN{sub 0} and associated reduced virulence.

  5. Decision-Making in Structure Solution using Bayesian Estimates of Map Quality: The PHENIX AutoSol Wizard

    SciTech Connect (OSTI)

    Terwilliger, T. C.; Adams, P. D.; Read, R. J.; McCoy, A. J.; Moriarty, Nigel W.; Grosse-Kunstleve, R. W.; Afonine, P. V.; Zwart, P. H.; Hung, L.-W.

    2009-03-01T23:59:59.000Z

    Estimates of the quality of experimental maps are important in many stages of structure determination of macromolecules. Map quality is defined here as the correlation between a map and the map calculated based on a final refined model. Here we examine 10 different measures of experimental map quality using a set of 1359 maps calculated by reanalysis of 246 solved MAD, SAD, and MIR datasets. A simple Bayesian approach to estimation of map quality from one or more measures is presented. We find that a Bayesian estimator based on the skew of histograms of electron density is the most accurate of the 10 individual Bayesian estimators of map quality examined, with a correlation between estimated and actual map quality of 0.90. A combination of the skew of electron density with the local correlation of rms density gives a further improvement in estimating map quality, with an overall correlation coefficient of 0.92. The PHENIX AutoSol Wizard carries out automated structure solution based on any combination of SAD, MAD, SIR, or MIR datasets. The Wizard is based on tools from the PHENIX package and uses the Bayesian estimates of map quality described here to choose the highest-quality solutions after experimental phasing.

  6. Results of the radiological survey at Greg's Auto Emporium, 60 State Highway 46, Lodi, New Jersey (LJ089)

    SciTech Connect (OSTI)

    Foley, R.D.; Floyd, L.M.

    1989-11-01T23:59:59.000Z

    Maywood Chemical Works (MCW) of Maywood, New Jersey, generated process wastes and residues associated with the production and refining of thorium and thorium compounds from monazite ores from 1916 to 1956. MCW supplied rare earth metals and thorium compounds to the Atomic Energy Commission and various other government agencies from the late 1940s to the mid-1950s. Area residents used the sandlike waste from this thorium extraction process mixed with tea and cocoa leaves as mulch in their yards. Some of these contaminated wastes were also eroded from the site into Lodi Brook. At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducts investigative radiological surveys of properties in the vicinity of MCW to determine whether a property is contaminated with radioactive residues, principally {sup 232}Th, derived from the MCW site. The survey typically includes direct measurement of gamma radiation levels and soil sampling for radionuclide analyses. The survey of this site, Greg's Auto Emporium, 60 State Highway 46, Lodi, New Jersey (LJ089), was conducted during 1988. 5 refs., 3 figs., 3 tabs.

  7. Year GBClass Make Model M/M/Specs EmisStd City Hiwy Green Score 2014 01_TS AUDI TT ROADSTER QUATTRO 2.0L 4, auto Awd [P] ULEV II / Bin 5 22 31 42

    E-Print Network [OSTI]

    Derisi, Joseph

    Year GBClass Make Model M/M/Specs EmisStd City Hiwy Green Score 2014 01_TS MERCEDES-BENZ SMART FORTWO (CONVERTIBLE) 1.0L 3, auto [P] ULEV II / Bin 5 34 38 53 2014 01_TS MERCEDES-BENZ SMART FORTWO (COUPE) 1.0L 3, auto [P] ULEV II / Bin 5 34 38 53 2014 01_TS MERCEDES

  8. A survey of repair practices for nuclear power plant containment metallic pressure boundaries

    SciTech Connect (OSTI)

    Oland, C.B.; Naus, D.J. [Oak Ridge National Lab., TN (United States)

    1998-05-01T23:59:59.000Z

    The Nuclear Regulatory Commission has initiated a program at the Oak Ridge National Laboratory to provide assistance in their assessment of the effects of potential degradation on the structural integrity and leaktightness of metal containment vessels and steel liners of concrete containments in nuclear power plants. One of the program objectives is to identify repair practices for restoring metallic containment pressure boundary components that have been damaged or degraded in service. This report presents issues associated with inservice condition assessments and continued service evaluations and identifies the rules and requirements for the repair and replacement of nonconforming containment pressure boundary components by welding or metal removal. Discussion topics include base and welding materials, welding procedure and performance qualifications, inspection techniques, testing methods, acceptance criteria, and documentation requirements necessary for making acceptable repairs and replacements so that the plant can be returned to a safe operating condition.

  9. Evaluation of bisphenol E cyanate ester for the resin-injection repair of advanced composites

    SciTech Connect (OSTI)

    Wilber Yaote Lio

    2009-12-19T23:59:59.000Z

    This thesis is a compilation of a general introduction and literature review that ties together the subsequent chapters which consist of two journal articles that have yet to be submitted for publication. The overall topic relates to the evaluation and application of a new class of cyanate ester resin with unique properties that lend it applicable to use as a resin for injection repair of high glass transition temperature polymer matrix composites. The first article (Chapter 2) details the evaluation and optimization of adhesive properties of this cyanate ester and alumina nanocomposites under different conditions. The second article (Chapter 3) describes the development and evaluation of an injection repair system for repairing delaminations in polymer matrix composites.

  10. Automatic coke oven heating control system at Burns Harbor for normal and repair operation

    SciTech Connect (OSTI)

    Battle, E.T.; Chen, K.L. [Bethlehem Steel Corp., Burns Harbor, IN (United States); [Bethlehem Steel Corp., PA (United States)

    1997-12-31T23:59:59.000Z

    An automatic heating control system for coke oven batteries was developed in 1985 for the Burns Harbor No. 1 battery and reported in the 1989 Ironmaking Conference Proceedings. The original system was designed to maintain a target coke temperature at a given production level under normal operating conditions. Since 1989, enhancements have been made to this control system so that it can also control the battery heating when the battery is under repair. The new control system has improved heating control capability because it adjusts the heat input to the battery in response to anticipated changes in the production schedule. During a recent repair of this 82 oven battery, the pushing schedule changed from 102 ovens/day to 88 ovens/day, then back to 102 ovens/day, then to 107 ovens/day. During this repair, the control system was able to maintain the coke temperature average standard deviation at 44 F, with a maximum 75 F.

  11. Hurricane-damaged Gulf of Mexico pipeline repaired with cold forging

    SciTech Connect (OSTI)

    Lewis, G. (Texaco Pipeline Inc., Houma, LA (United States)); DeGruy, P. (Texaco Inc., New Orleans, LA (United States)); Avery, L. (Big Inch Marine Systems Inc., Lafayette, LA (United States))

    1993-05-03T23:59:59.000Z

    Damage to Texaco Pipeline Inc.'s Eugene Island Pipeline System (EIPS) in last year's Hurricane Andrew prompted a complex repair project unique for the Gulf of Mexico. Damage, suffered when the anchor of a runaway semisubmersible drilling rig crashed into the 20-in. EPIS during the height of the storm, caused the pipeline to fail under pressure within 48 hr. after start-up following the storm. The paper describes the importance of the EIPS; system safety; Andrew's damage; locating the leak; repair options; the chosen system; mechanical bonding; end connectors and ball flanges; and diving operations.

  12. Bosh repairs No. 3 blast furnace, Edgar Thomson Plant Mon Valley Works

    SciTech Connect (OSTI)

    Stoupis, M.G.

    1993-01-01T23:59:59.000Z

    The paper describes in detail the steps taken from quenching to dry out of the furnace to repair the bosh area of the No.3 blast furnace. Inspection of the area revealed that there was no brick anywhere in the bosh. Brick in the tuyere breast area had been peeled back to reveal the steel plate, and descaling revealed 14 pipes fully exposed. None were leaking, but one seemed badly deteriorated. Conventional repairs could not take place before the scheduled blow-in. Installation of coolers were instead tried.

  13. Remote reactor repair: GTA (gas tungsten Arc) weld cracking caused by entrapped helium

    SciTech Connect (OSTI)

    Kanne, W.R. Jr.

    1988-01-01T23:59:59.000Z

    A repair patch was welded to the wall of a nuclear reactor tank using remotely controlled thirty-foot long robot arms. Further repair was halted when gas tungsten arc (GTA) welds joining type 304L stainless steel patches to the 304 stainless steel wall developed toe cracks in the heat-affected zone (HAZ). The role of helium in cracking was investigated using material with entrapped helium from tritium decay. As a result of this investigation, and of an extensive array of diagnostic tests performed on reactor tank wall material, helium embrittlement was shown to be the cause of the toe cracks.

  14. Mitral Web -A New Concept for Mitral Valve Repair: Improved Engineering Design and In-Vitro Studies

    E-Print Network [OSTI]

    Pekkan, Kerem

    Mitral Web - A New Concept for Mitral Valve Repair: Improved Engineering Design and In of Biomedical Engineering, Georgia Institute of Technology, GA, USA Myxomatous mitral valve disease is currently reported that mitral valve repair is preferable to valve replace- ment, as it offers certain advantages

  15. Restoration and repair of 30-year old cooling towers at the Paducah Gaseous Diffusion Plant, Phase I. Draft 1

    SciTech Connect (OSTI)

    Shelton, M.F.

    1985-01-01T23:59:59.000Z

    Early in 1980, a comprehensive reliability study was made to ascertain the ability of the present 30-year old recirculating water system to meet the anticipated load demand through the year 2000. The findings and recommendations of this study were used as a guide to schedule uprating and repairs. This paper deals with the underground distribution system and cooling tower repairs.

  16. The Role of Nucleotide Excision Repair in Restoring Replication Following UV-Induced Damage in Escherichia coli

    E-Print Network [OSTI]

    Courcelle, Justin

    The Role of Nucleotide Excision Repair in Restoring Replication Following UV-Induced Damage DNA synthesis in the absence of nucleotide excision repair does not promote cell survivalA mutants....................... 26 Following low doses of UV irradiation cells lacking nucleotide excision

  17. Hot repair of ceramic burner on hot blast stoves at USS/Kobe`s {number_sign}3 blast furnace

    SciTech Connect (OSTI)

    Bernarding, T.F.; Chemorov, M.; Shimono, S.; Phillips, G.R.

    1997-12-31T23:59:59.000Z

    During the 1992 reline of the No. 3 blast furnace, three new stoves were constructed. The design of the stoves, equipped with internal ceramic burners, was for providing a hot blast temperature of 2,000 F at a wind rate of 140,000 SCFM. After 3 years the performance had deteriorated so the burners were cleaned. When a second cleaning did not improve the performance of No. 3 blast furnace, it was decided to repair the refractory while still hot. The paper describes the hot repair procedures, taking a stove off for repairs, maintenance heat up during repairs, two stove operation, stove commissioning, repair of a ceramic burner, and wet gas prevention.

  18. Toward a State of Good Repair for Railroad Bridges through Structural Health Monitoring

    E-Print Network [OSTI]

    Bustamante, Fabián E.

    Toward a State of Good Repair for Railroad Bridges through Structural Health Monitoring NUTC of this research is to add a new tool to the asset management toolbox: structural health monitoring, particularly is Structural Health Monitoring (SHM)? SHM is process of intelligently collecting data from sensors on critical

  19. Multilayer sulfur-resistant composite metal membranes and methods of making and repairing the same

    DOE Patents [OSTI]

    Way, J. Douglas; Hatlevik, Oyvind

    2014-07-15T23:59:59.000Z

    The invention relates to thin, hydrogen-permeable, sulfur-resistant membranes formed from multi-layers of palladium or palladium-alloy coatings on porous, ceramic or metal supports, methods of making these membranes, methods of repairing layers of these membranes and devices that incorporate these membranes.

  20. Development/Plasticity/Repair Deletion of ERK2 Mitogen-Activated Protein Kinase

    E-Print Network [OSTI]

    Development/Plasticity/Repair Deletion of ERK2 Mitogen-Activated Protein Kinase Identifies Its Key University, Piscataway, New Jersey 08855-8082 The mitogen-activated protein (MAP) kinases ERK1 and ERK2-specific functions in vivo. We have examined the role of ERK2 in neural development by conditional inactivation

  1. Development/Plasticity/Repair The ERK2 Mitogen-Activated Protein Kinase Regulates the

    E-Print Network [OSTI]

    Development/Plasticity/Repair The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing Oligodendrocytedevelopmentistightlycontrolledbyavarietyofextracellulargrowthanddifferentiationfactors.Themitogen-activated protein kinases (MAPKs), ERK1 and ERK2, are critical intracellular signaling (ERKs) are ubiquitously expressed, coordinately regulated, and highly similar, but Erk2 deletion in mice

  2. Development/Plasticity/Repair Phosphatidylinositol 3-Kinase Activates ERK in Primary

    E-Print Network [OSTI]

    Clapham, David E.

    Development/Plasticity/Repair Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory activation to inflammatory pain. We further investigated the correlationbetweenthePI3KandtheERK294002 and wortmannin, indicative of the activation of PI3K by both agents. ERK activation by capsaicin

  3. Development/Plasticity/Repair Disrupted ERK Signaling during Cortical Development Leads

    E-Print Network [OSTI]

    Development/Plasticity/Repair Disrupted ERK Signaling during Cortical Development Leads to Abnormal disorders arising from copy number variations in the ERK (extracellular signal-regulated kinase) MAP that these changes are due to ERK-dependent dysregulation of cyclin D1 and p27Kip1 , resulting in cell cycle

  4. Lazy Means Smart: Reducing Repair Bandwidth Costs in Erasure-coded Distributed Storage

    E-Print Network [OSTI]

    Alvisi, Lorenzo

    ,10)-encoded storage in this system results in hundreds of terabytes of daily recovery traffic through Top- Of an energy-conserving, storage-efficient, hybrid hadoop compute cluster. In Proceedings of the 2010Lazy Means Smart: Reducing Repair Bandwidth Costs in Erasure-coded Distributed Storage Mark

  5. FFaacciilliittiieess MMaannaaggeemmeenntt//EEnnvviirroonnmmeennttaall HHeeaalltthh && SSaaffeettyy Hazardous Work Area/Equipment Repair Form

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    Hazardous Work Area/Equipment Repair Form Form Instructions: Client is responsible for completing this form to assure that equipment and/or immediate work areas are not contaminated with any hazardous materials, tissue, etc.) Do Safety Hazards exist in the work area? N ___ Y ___ (Electrical, burn, or trip hazards

  6. Fast Interactive Simulations of Mitral Valve Repair Neil A. Tenenholtz, Peter E. Hammer, Robert D. Howe

    E-Print Network [OSTI]

    Fast Interactive Simulations of Mitral Valve Repair Neil A. Tenenholtz, Peter E. Hammer, Robert D. Howe Keywords: Surgical simulation, human-computer interaction, haptics, mitral valve, cardiac surgery. I. Problem Solved A healthy mitral valve ensures the one-way flow of oxygenated blood from the left

  7. Repair and Replacement projects help FM to honor its commitment to

    E-Print Network [OSTI]

    Gulliver, Robert

    of the University. Services provided fall into three major categories: preventive maintenance, routine repairs friendly power. Energy Management is continually recognized for the superior maintenance. · Maintenance (www.facm.umn. edu/services/maintenance.html) Maintenance Operations preserves the physical assets

  8. Home Maintenance and Repair Owning a home is a major responsibility.

    E-Print Network [OSTI]

    maintenance is conducted. Regular, preventive maintenance can pay off in peace of mind, utility cost savings, routine maintenance helps to prolong the life of the home and may prevent the need for major repairs of Benjamin Franklin, "An ounce of prevention is worth a pound of cure." Regular, routine maintenance enhances

  9. Investigation of Corrosion Damage and Repair System in a Concrete Jetty Structure

    E-Print Network [OSTI]

    Mobasher, Barzin

    Investigation of Corrosion Damage and Repair System in a Concrete Jetty Structure Farid Moradi of the deterioration was reinforcement corrosion, which initiated within few years after the completion of the jetty structure. The structure underwent major corrosion rehabilitation after 7 years of service. Despite the use

  10. Development/Plasticity/Repair The Bone Morphogenetic Protein Roof Plate Chemorepellent

    E-Print Network [OSTI]

    Butler, Samantha

    Development/Plasticity/Repair The Bone Morphogenetic Protein Roof Plate Chemorepellent Regulates, Toronto, Ontario, Canada M5G 1X8 Commissural spinal axons extend away from the roof plate (RP) in response to the dorsal midline and are generated by the bone morphogenetic proteins (BMPs) in the roof plate (RP) (Liem

  11. Development/Plasticity/Repair A Structural MRI Study of Human Brain Development from

    E-Print Network [OSTI]

    Utah, University of

    Development/Plasticity/Repair A Structural MRI Study of Human Brain Development from Birth to 2 Carolina, Chapel Hill, North Carolina 27599-7510 Brain development in the first 2 years after birth and schizophrenia. Knowledge regarding this period is currently quite limited. We studied structural brain

  12. Efficacy of Low Level Laser Therapy After Hand Flexor Tendon Repair

    SciTech Connect (OSTI)

    Ayad, K. E.; Abd El Mejeed, S. F. [Faculty of Physical Therapy, Cairo University (Egypt); El Gohary, H. M.; Abd Elrahman, M.; Bekheet, A. B. [Al Sahel Teaching Hospital, Cairo (Egypt)

    2009-09-27T23:59:59.000Z

    Flexor tendon injury is a common problem requiring suturing repair followed by early postoperative mobilization. Muscle atrophy, joint stiffness, osteoarthritis, infection, skin necrosis, ulceration of joint cartilage and tendocutaneous adhesion are familiar complications produced by prolonged immobilization of surgically repaired tendon ruptures. The purpose of this study was to clarify the importance of low level laser therapy after hand flexor tendon repair in zone II. Thirty patients aging between 20 and 40 years were divided into two groups. Patients in group A (n = 15) received a conventional therapeutic exercise program while patients in group B (n = 15) received low level laser therapy combined with the same therapeutic exercise program. The results showed a statistically significant increase in total active motion of the proximal and distal interphalangeal joints as well as maximum hand grip strength at three weeks and three months postoperative, but improvement was more significant in group B. It was concluded that the combination of low level laser therapy and early therapeutic exercises was more effective than therapeutic exercises alone in improving total active motion of proximal and distal interphalangeal joints and hand grip strength after hand flexor tendon repair.

  13. Provably Repairing the ISO/IEC 9798 Standard for Entity Authentication

    E-Print Network [OSTI]

    Basin, David

    , or authentication of transmitted data [27,33]. The ISO (International Organization for Standardization) and IECProvably Repairing the ISO/IEC 9798 Standard for Entity Authentication David Basin, Cas Cremers the family of entity authentication protocols defined by the ISO/IEC 9798 standard and find numerous

  14. Provably Repairing the ISO/IEC 9798 Standard for Entity Authentication

    E-Print Network [OSTI]

    Basin, David

    (International Organization for Standardization) and IEC (Interna- tional Electrotechnical Commission) jointlyProvably Repairing the ISO/IEC 9798 Standard for Entity Authentication David Basin, Cas Cremers the family of entity authentication proto- cols defined by the ISO/IEC 9798 standard and find numerous

  15. Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction1

    E-Print Network [OSTI]

    Stuart, Jeffrey A.

    Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction1 of Biology, Brock University, St. Catharines, Ontario, Canada; and Gazi University, Faculty of Pharmacy in kidney mitochondria. 4. CR increases nuclear BER activity BER activity and the activities of proteins

  16. Development/Plasticity/Repair Dendritic Spine Dynamics Regulate the Long-Term Stability

    E-Print Network [OSTI]

    van Rossum, Mark

    Development/Plasticity/Repair Dendritic Spine Dynamics Regulate the Long-Term Stability of Synaptic Plasticity Cian O'Donnell,1,2 Matthew F. Nolan,3 and Mark C. W. van Rossum1 1Institute for Adaptive of Edinburgh, Edinburgh EH8 9XD, United Kingdom Long-term synaptic plasticity requires postsynaptic influx

  17. Development/Plasticity/Repair A Refractory Period for Rejuvenating GABAergic Synaptic

    E-Print Network [OSTI]

    Gruner, Daniel S.

    Development/Plasticity/Repair A Refractory Period for Rejuvenating GABAergic Synaptic Transmission and Ocular Dominance Plasticity with Dark Exposure Shiyong Huang,1* Yu Gu,2* Elizabeth M. Quinlan,2 Dark exposure initiated in adulthood reactivates robust ocular dominance plasticity in the visual

  18. Development/Plasticity/Repair Simultaneous NMDA-Dependent Long-Term Potentiation of

    E-Print Network [OSTI]

    Segal, Menahem

    Development/Plasticity/Repair Simultaneous NMDA-Dependent Long-Term Potentiation of EPSCs and Long activity-dependent long-term plasticity of neuronal networks is the interplay between excitatory, whereas a nitric oxide synthase inhibitor was ineffec- tive. Finally, network-induced plasticity

  19. The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly

    E-Print Network [OSTI]

    Mecham, Robert

    The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly Adrian Shifren and Robert P properties of the lung are largely determined by the connective tissue networks laid down during development. The macromolecules most important for lung mechanics and structural integrity are collagen, elastin

  20. Development/Plasticity/Repair Identification of Modulators of Hair Cell Regeneration in the

    E-Print Network [OSTI]

    Rubel, Edwin

    Development/Plasticity/Repair Identification of Modulators of Hair Cell Regeneration compounds that modulate hair cell regeneration in zebrafish. Of the 1680 compounds evaluated, we identified,aresyntheticglucocorticoidsthatpotentiatedhaircellnumbersduringregenerationandalsoinducedhair cell addition in the absence of damage. BrdU analysis confirmed that the extra hair cells arose from

  1. Development/Plasticity/Repair Hair Cell Replacement in Adult Mouse Utricles after

    E-Print Network [OSTI]

    Rubel, Edwin

    Development/Plasticity/Repair Hair Cell Replacement in Adult Mouse Utricles after Targeted Ablation of Hair Cells with Diphtheria Toxin Justin S. Golub,1 Ling Tong,1 Tot B. Ngyuen,1 Cliff R. Hume,1 Richard developed a transgenic mouse to permit conditional and selective ablation of hair cells in the adult mouse

  2. Daily dose monitoring with atlas-based auto-segmentation on diagnostic quality CT for prostate cancer

    SciTech Connect (OSTI)

    Li, Wen; Vassil, Andrew; Xia, Ping [Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44106 (United States)] [Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44106 (United States); Zhong, Yahua [Department of Radiation Oncology, Zhongnan Hospital, Wuhan 430071 (China)] [Department of Radiation Oncology, Zhongnan Hospital, Wuhan 430071 (China)

    2013-11-15T23:59:59.000Z

    Purpose: To evaluate the feasibility of daily dose monitoring using a patient specific atlas-based autosegmentation method on diagnostic quality verification images.Methods: Seven patients, who were treated for prostate cancer with intensity modulated radiotherapy under daily imaging guidance of a CT-on-rails system, were selected for this study. The prostate, rectum, and bladder were manually contoured on the first six and last seven sets of daily verification images. For each patient, three patient specific atlases were constructed using manual contours from planning CT alone (1-image atlas), planning CT plus first three verification CTs (4-image atlas), and planning CT plus first six verification CTs (7-image atlas). These atlases were subsequently applied to the last seven verification image sets of the same patient to generate the auto-contours. Daily dose was calculated by applying the original treatment plans to the daily beam isocenters. The autocontours and manual contours were compared geometrically using the dice similarity coefficient (DSC), and dosimetrically using the dose to 99% of the prostate CTV (D99) and the D5 of rectum and bladder.Results: The DSC of the autocontours obtained with the 4-image atlases were 87.0%± 3.3%, 84.7%± 8.6%, and 93.6%± 4.3% for the prostate, rectum, and bladder, respectively. These indices were higher than those from the 1-image atlases (p < 0.01) and comparable to those from the 7-image atlases (p > 0.05). Daily prostate D99 of the autocontours was comparable to those of the manual contours (p= 0.55). For the bladder and rectum, the daily D5 were 95.5%± 5.9% and 99.1%± 2.6% of the planned D5 for the autocontours compared to 95.3%± 6.7% (p= 0.58) and 99.8%± 2.3% (p < 0.01) for the manual contours.Conclusions: With patient specific 4-image atlases, atlas-based autosegmentation can adequately facilitate daily dose monitoring for prostate cancer.

  3. RCRA Facility Investigation/Remedial Investigation Report with Baseline Risk Assessment for the Central Shops Burning/Rubble Pit (631-6G), Volume 1 Final

    SciTech Connect (OSTI)

    NONE

    1996-04-01T23:59:59.000Z

    The Burning/Rubble Pits at the Savannah River Site were usually shallow excavations approximately 3 to 4 meters in depth. Operations at the pits consisted of collecting waste on a continuous basis and burning on a monthly basis. The Central Shops Burning/Rubble Pit 631- 6G (BRP6G) was constructed in 1951 as an unlined earthen pit in surficial sediments for disposal of paper, lumber, cans and empty galvanized steel drums. The unit may have received other materials such as plastics, rubber, rags, cardboard, oil, degreasers, or drummed solvents. The BRP6G was operated from 1951 until 1955. After disposal activities ceased, the area was covered with soil. Hazardous substances, if present, may have migrated into the surrounding soil and/or groundwater. Because of this possibility, the United States Environmental Protection Agency (EPA) has designated the BRP6G as a Solid Waste Management Unit (SWMU) subject to the Resource Conservation Recovery Act/Comprehensive Environmental Response, Compensation and Liability Act (RCRA/CERCLA) process.

  4. Using Differential Adhesion to Control Self-Assembly and Self-Repair of Collections of Modular Mobile Robots 

    E-Print Network [OSTI]

    Ottery, Peter

    This thesis presents a novel distributed control method which allows a collection of independently mobile robotic units, with two or three dimensional movement, to self-assemble into self-repairing hierarchical structures. ...

  5. The role of vascular endothelial growth factor (VEGF) in repair and recovery from acute respiratory distress syndrome (ARDS) 

    E-Print Network [OSTI]

    Medford, Andrew R.L

    2007-01-01T23:59:59.000Z

    Acute Respiratory Distress Syndrome (ARDS) is the most extreme form of acute lung injury and continues to have a significant morbidity and mortality. Unfortunately, the mechanisms involved in the recovery and repair of ...

  6. Repair of localized defects in multilayer-coated reticle blanks for extreme ultraviolet lithography

    DOE Patents [OSTI]

    Stearns, Daniel G. (Los Altos, CA); Sweeney, Donald W. (San Ramon, CA); Mirkarimi, Paul B. (Sunol, CA)

    2004-11-23T23:59:59.000Z

    A method is provided for repairing defects in a multilayer coating layered onto a reticle blank used in an extreme ultraviolet lithography (EUVL) system. Using high lateral spatial resolution, energy is deposited in the multilayer coating in the vicinity of the defect. This can be accomplished using a focused electron beam, focused ion beam or a focused electromagnetic radiation. The absorbed energy will cause a structural modification of the film, producing a localized change in the film thickness. The change in film thickness can be controlled with sub-nanometer accuracy by adjusting the energy dose. The lateral spatial resolution of the thickness modification is controlled by the localization of the energy deposition. The film thickness is adjusted locally to correct the perturbation of the reflected field. For example, when the structural modification is a localized film contraction, the repair of a defect consists of flattening a mound or spreading out the sides of a depression.

  7. Nondestructive evaluation and characterization of damage and repair to continuous-fiber ceramic composite panels.

    SciTech Connect (OSTI)

    Sun, J. G.; Petrak, D. R.; Pillai, T. A. K.; Deemer, C.; Ellingson, W. A.

    1998-04-01T23:59:59.000Z

    Continuous fiber ceramic matrix composites are currently being developed for a variety of high-temperature applications. Because of the high costs of making these components, minor damage incurred during manufacturing or operation must be rewired in order to extend the life of the components. In this study, five ceramic-grade Nicalon{trademark} fiber/SiNC-matrix composite panels were intentionally damaged with a pendulum-type impactor during an impact test. The damaged panels were then repaired at Dow Corning Corporation. Three nondestructive evaluation (NDE) methods were used to study the characteristics of the panels after the damage and again after the panels were repaired. The NDE methods were X-ray radiography, infrared thermal imaging, and air-coupled ultrasound. The results showed that the impact test induced various types of damage in the panels. The NDE data that were obtained by the three NDE methods were correlated with each other.

  8. Weld Repair of a Stamped Pressure Vessel in a Radiologically Controlled Zone

    SciTech Connect (OSTI)

    Cannell, Gary L. [Fluor Enterprises, Inc.; Huth, Ralph J. [CH2MHill Plateau Remediation Company; Hallum, Randall T. [Fluor Government Group

    2013-08-26T23:59:59.000Z

    In September 2012 an ASME B&PVC Section VIII stamped pressure vessel located at the DOE Hanford Site Effluent Treatment Facility (ETF) developed a through-wall leak. The vessel, a steam/brine heat exchanger, operated in a radiologically controlled zone (by the CH2MHill PRC or CHPRC), had been in service for approximately 17 years. The heat exchanger is part of a single train evaporator process and its failure caused the entire system to be shut down, significantly impacting facility operations. This paper describes the activities associated with failure characterization, technical decision making/planning for repair by welding, logistical challenges associated with performing work in a radiologically controlled zone, performing the repair, and administrative considerations related to ASME code requirements.

  9. Subterranean barriers, methods, and apparatuses for forming, inspecting, selectively heating, and repairing same

    DOE Patents [OSTI]

    Nickelson, Reva A. (Shelley, ID); Sloan, Paul A. (Rigby, ID); Richardson, John G. (Idaho Falls, ID); Walsh, Stephanie (Idaho Falls, ID); Kostelnik, Kevin M. (Idaho, ID)

    2009-04-07T23:59:59.000Z

    A subterranean barrier and method for forming same are disclosed, the barrier including a plurality of casing strings wherein at least one casing string of the plurality of casing strings may be affixed to at least another adjacent casing string of the plurality of casing strings through at least one weld, at least one adhesive joint, or both. A method and system for nondestructively inspecting a subterranean barrier is disclosed. For instance, a radiographic signal may be emitted from within a casing string toward an adjacent casing string and the radiographic signal may be detected from within the adjacent casing string. A method of repairing a barrier including removing at least a portion of a casing string and welding a repair element within the casing string is disclosed. A method of selectively heating at least one casing string forming at least a portion of a subterranean barrier is disclosed.

  10. Template strand scrunching during DNA gap repair synthesis by human polymerase [lamda

    SciTech Connect (OSTI)

    Garcia-Diaz, Miguel; Bebenek, Katarzyna; Larrea, Andres A.; Havener, Jody M.; Perera, Lalith; Krahn, Joseph M.; Pedersen, Lars C.; Ramsden, Dale A.; Kunkel, Thomas A.; (NIH); (UNC)

    2009-09-25T23:59:59.000Z

    Family X polymerases such as DNA polymerase {lambda}(Pol {lambda}) are well suited for filling short gaps during DNA repair because they simultaneously bind both the 5{prime} and 3{prime} ends of short gaps. DNA binding and gap filling are well characterized for 1-nucleotide (nt) gaps, but the location of yet-to-be-copied template nucleotides in longer gaps is unknown. Here we present crystal structures revealing that, when bound to a 2-nt gap, Pol {lambda} scrunches the template strand and binds the additional uncopied template base in an extrahelical position within a binding pocket that comprises three conserved amino acids. Replacing these amino acids with alanine results in less processive gap filling and less efficient NHEJ when 2-nt gaps are involved. Thus, akin to scrunching by RNA polymerase during transcription initiation, scrunching occurs during gap filling DNA synthesis associated with DNA repair.

  11. "You Can Do It" Basic Home Repair Using Hand and Power Tools

    E-Print Network [OSTI]

    1 "You Can Do It" Basic Home Repair Using Hand and Power Tools by Janie L. Harris Extension Housing guard housing. Place the tool rest 1/8 inch from the wheel on bench-mounted units. Before starting://www.cdc.gov/nasd/docs/ University of Denver, Risk Management http://www.du.edu/risk/Tool_Safety.html #12;2 "You Can Do It" Basic

  12. The strengthening and repair of underground structures: A new approach to the management of nuclear waste

    SciTech Connect (OSTI)

    Colgate, S.A.

    1991-01-01T23:59:59.000Z

    This paper presents three closely related ideas and technologies: (1) The secure, repairable, long time confinement of nuclear radioactive waste underground by a large surrounding region of compressive overstress; (2) The inherent tectonic weakness and vulnerability of the normal underground environment and its modification by overstress; (3) The process of creating overstress by the sequential periodic high pressure injection of a finite gel strength rapid setting grout. 12 refs., 6 figs.

  13. Note: A Graph-Theoretical Approach to Level of Repair Analysis

    E-Print Network [OSTI]

    2004-08-29T23:59:59.000Z

    Aug 29, 2004 ... cilities to minimize overall life-cycle costs. ... decisions, LORA seeks to determine an optimal provision of repair and maintenance ... Their heuristic is based on a relaxation of LORA into a pair of ... R2 is a consequence of R1 and a policy of .... from the fact that one can find a minimum cut in N(B) in time O(n2.

  14. Development program to certify composite doubler repair technique for commercial aircraft

    SciTech Connect (OSTI)

    Roach, D.P.

    1997-07-01T23:59:59.000Z

    Commercial airframes exceeding 20 service years often develop crack and corrosion flaws. Bonded composite doublers offer a cost effective method to safely extend aircraft lives. The Federal Aircraft Authority (FAA) has completed a project to introduce composite doubler repair technology to the commercial aircraft industry. Instead of riveting steel or aluminum plates for repair, a single composite doubler may be bonded to the damaged structure. Adhesive bonding eliminates stress concentrations caused by fastener holes. Composites are readily formed into complex shapes for repairing irregular components. Also, composite doublers can be tailored to meet specific anisotropy needs, eliminating structural stiffening in directions other than those required. Other advantages include corrosion resistance, a high strength-to-weight ratio, and potential time savings in installation. One phase of this study developed general methodologies and test programs to ensure proper performance of the technique. A second phase focused on reinforcement of an L-1011 door frame, and encompassed all lifetime tasks such as design, analysis, installation, and nondestructive inspection. This paper overviews the project and details the activities conducted to gain FAA approval for composite doubler use. Structural tests evaluated the damage tolerance and fatigue performance of composite doublers while finite element models were generated to study doubler design issues. Nondestructive inspection procedures were developed and validated using full-scale test articles. Installation dry-runs demonstrated the viability of applying composite doublers in hangar environments. The project`s documentation package was used to support installation of a Boron-Epoxy composite repair on a Delta Air Lines L-1011 aircraft. A second product of the results is a Lockheed Service Bulletin which allows the door corner composite doubler to be installed on all L-1011 aircraft. 9 refs., 10 figs., 2 tabs.

  15. Lethal Hemorrhage Caused by Aortoesophageal Fistula Secondary to Stent-Graft Repair of the Thoracic Aorta

    SciTech Connect (OSTI)

    Sager, Hendrik B., E-mail: hendrik.sager@uk-sh.de [Universitaet zu Luebeck, Medizinische Klinik II (Germany); Wellhoener, Peter [Universitaet zu Luebeck, Medizinische Klinik I (Germany); Wermelt, Johanna A. [Klinikum Neustadt, Klinik fuer Innere Medizin (Germany); Schunkert, Heribert; Kurowski, Volkhard [Universitaet zu Luebeck, Medizinische Klinik II (Germany)

    2011-02-15T23:59:59.000Z

    Aortoesophageal fistula (AEF) is a rare but life-threatening complication after endovascular or surgical aortic repair. Here we report a patient with AEF secondary to aortic stent-placement 2 years earlier who presented with hematemesis and died from hemorrhagic shock. By means of this case and the literature, we highlight potential bleeding sources in such a scenario because this is of crucial importance for the management strategy.

  16. REPAIR OF A DAMAGED PART ON HYDRAULIC TRACT KAPLAN TURBINE WITH "LIQUID METAL"

    E-Print Network [OSTI]

    Fuad ?atovi?; Prof Emeritus; Edin Džiho Msc; Mostar Bih; Mustafa Šehi?; Hydroelectric Power Plant Neretva; Jablanica Bih

    During 2011 on unit no.2 reparation work was carried out aimed at fault removal on Kaplan turbine impeller, while extending the lifespan of the entire installed equipment. The overhaul included all vital parts, replacement of all gasket compresses, machine processing to achieve the required tolerances, NDT equipment control according to "Quality Control Plan", repairing equipment, etc. This paper describes the recovery of defects on the blades of the guide vanes using epoxy masses.

  17. Endovascular Repair of a Pseudoaneurysm of the Abdominal Aorta Secondary to Translumbar Aortography

    SciTech Connect (OSTI)

    Mir, Naheed; Nunzio, Mario De; Pollock, John G [Derbyshire Royal Infirmary, Department of Clinical Radiology (United Kingdom)], E-mail: JG.Pollock@derbyhospitals.nhs.uk

    2006-12-15T23:59:59.000Z

    This report describes an incidental finding of a pseudoaneurysm of the abdominal aorta on a computed tomography (CT) renal angiogram during investigation of chronic renal failure in a 73-year-old man. The patient had undergone a translumbar aortogram 20 years previously. An increase in the size of the aneurysm by 7 mm over 6 months prompted treatment and the aneurysm underwent successful endovascular repair with a custom-made stent-graft.

  18. LOCOMOTIVE DATA ACQUISITION PACKAGE

    E-Print Network [OSTI]

    Abbott, Robert K.

    2011-01-01T23:59:59.000Z

    a high level of LDAP equipment reliability, in an extremelyresulted in low reliability because the equipment designersreliability and maintenance data base from repair shop records; Characterizing locomotive equipment

  19. The DNA Single-Strand Break Repair Machinery Facilitates CAF-1-Mediated Histone Deposition at Oxidative DNA Strand Breaks

    E-Print Network [OSTI]

    Arman Nabatiyan; Zhihong Zeng; Keith W. Caldecott

    2012-02-01T23:59:59.000Z

    Oxidative DNA single strand breaks arise continuously in cells and defects in their repair have been implicated in neurological disease. While much progress has been made in understanding how chromosomal single strand breaks are repaired little is known about the changes chromatin structure that accompany this process. Here, we show that nascent recombinant histone H3.1 protein accumulates and is deposited into chromatin at sites of DNA strand breakage in quiescent human cells following oxidative stress, and that core components of the single-strand break repair machinery are required for this process. We show that the SSBR sensor and scaffold proteins poly (ADP-ribose) polymerase and XRCC1 facilitate accumulation of chromatin assembly factor-1 (CAF-1) at sites of oxidative DNA strand breakage, which in turn mediates the deposition of Histone H3.1. We also demonstrate that depletion of CAF-1 slows global rates of DNA strand break repair in quiescent cells following oxidative stress, demonstrating that single-strand break repair and histone deposition are tightly coordinated processes. These data describe a novel role for the DNA singlestrand break repair machinery and implicate histone turnover as a core component of the cellular response of quiescent cells to oxidative damage.

  20. Plasma transferred arc repair welding of the nickel-base superalloy IN-738LC

    SciTech Connect (OSTI)

    Su, C.Y.; Chou, C.P. [National Chiao Tung Univ., Hsinchu (Taiwan, Province of China). Dept. of Mechanical Engineering; Wu, B.C.; Lih, W.C. [Industrial Technology Research Inst., Hsinchu (Taiwan, Province of China). Materials Research Labs.

    1997-10-01T23:59:59.000Z

    Plasma transferred arc welding (PTA) has been considered a promising process to restore worn areas of land-based gas turbine blades and vanes. The objective of this investigation was to study the effect of PTA welding on the repairing of IN-738LC superalloy components. Tensile tests were conducted on specimens welded with various combinations of parameters. Room temperature, 760 C, and 980 C were selected as tensile test temperatures. High-temperature phase transformed, during solidification, were identified by differential thermal analysis (DTA). The weld-pool shapes and microstructures of welded specimens prepared by various welding parameters were evaluated by optical metallography (OM), a scanning electron microscope (SEM) equipped with energy dispersive x-ray spectrometer (EDS), and microhardness testing. Results of this study showed that PTA welded specimens exhibited 96% nominal tensile strength of IN-738LC base materials. Specimen failure was observed predominantly in the base materials instead of in the heat-affected zone (HAZ) for gas tungsten arc weld (GTAW) repair weldments. IN-738LC is considered susceptible to weld cracking during fusion welding; however, using a low-input repair welding process (PTA), cracking susceptibility could be minimized by the optimized welding parameters.

  1. LENS repair and modification of metal NW components:materials and applications guide.

    SciTech Connect (OSTI)

    Smugeresky, John E. (Sandia National Laboratories, Livermore, CA); Gill, David Dennis; Oberhaus, Jason (BWXT Y-12); Adams, Thad (Savannah River National Laboratory); VanCamp, Chad (Kansas City Plant)

    2006-11-01T23:59:59.000Z

    Laser Engineered Net Shaping{trademark} (LENS{reg_sign}) is a unique, layer additive, metal manufacturing technique that offers the ability to create fully dense metal features and components directly from a computer solid model. LENS offers opportunities to repair and modify components by adding features to existing geometry, refilling holes, repairing weld lips, and many other potential applications. The material deposited has good mechanical properties with strengths typically slightly higher that wrought material due to grain refinement from a quickly cooling weld pool. The result is a material with properties similar to cold worked material, but without the loss in ductility traditionally seen with such treatments. Furthermore, 304L LENS material exhibits good corrosion resistance and hydrogen compatibility. This report gives a background of the LENS process including materials analysis addressing the requirements of a number of different applications. Suggestions are given to aid both the product engineer and the process engineer in the successful utilization of LENS for their applications. The results of testing on interface strength, machinability, weldability, corrosion resistance, geometric effects, heat treatment, and repair strategy testing are all included. Finally, the qualification of the LENS process is briefly discussed to give the user confidence in selecting LENS as the process of choice for high rigor applications. The testing showed LENS components to have capability in repair/modification applications requiring complex castings (W80-3 D-Bottle bracket), thin wall parts requiring metal to be rebuilt onto the part (W87 Firing Set Housing and Y-12 Test Rings), the filling of counterbores for use in reservoir reclamation welding (SRNL hydrogen compatibility study) and the repair of surface defects on pressure vessels (SRNL gas bottle repair). The material is machinable, as testing has shown that LENS deposited material machines similar to that of welded metal. Tool wear is slightly higher in LENS material than in wrought material, but not so much that one would be concerned with increased tooling cost. The LENS process achieved process qualification for the AY1E0125 D-Bottle Bracket from the W80-3 LEP program, and in the effort, also underwent testing in weapons environments. These tests included structural dynamic response testing and drop testing. The LENS deposited parts were compared in these tests with conventionally machined parts and showed equivalency to such an extent that the parts were accepted for use in parallel path subsystem-level weapon environment testing. The evaluation of LENS has shown that the process can be a viable option when either complete metal parts are needed or existing metal parts require modification or repair. The LENS Qualification Technology Investment team successfully investigated new applications for the LENS process and showed that it has great applicability across the Nuclear Weapons Complex as well as in other high rigor applications.

  2. Are you getting an error message in UniFi Plus? (suggestion...check the auto-hint line!) In most cases, Unifi Plus does not prominently display error messages; instead, the error message will be

    E-Print Network [OSTI]

    Peak, Derek

    Are you getting an error message in UniFi Plus? (suggestion...check the auto-hint line!) In most cases, Unifi Plus does not prominently display error messages; instead, the error message and processing messages Keyboard shortcuts Instructions for accessing other blocks, windows or forms from

  3. Anode-cathode voltage drop of a rotating arc in an auto-expansion circuit-breaker filled with SF6-N2 mixtures

    SciTech Connect (OSTI)

    Beauvois, V.; Legros, W.; Scarpa, P. [Inst. Montefiore, Liege (Belgium)] [and others

    1995-12-31T23:59:59.000Z

    In auto-expansion circuit-breakers, the power dissipated by the arc itself heats the surrounding gas, inducing a pressure build up in the {open_quotes}upstream volume{close_quotes} and giving rise to a gas flow which blows the extinguishing arc. Moreover, in the studied apparatus, a magnetic field, due to the current flowing in a coil, provides arc radial stability and leads to arc rotation which efficiently reduces electrode erosion. In such a circuit-breaker, it is obvious that arc-gas and arc-electrode interactions are essential and govern. the energy balance in the plasma region. This paper deals more specifically with the phenomena occurring at the arc-electrode interfaces. It relates results of experiments carried out to determine the anode-cathode voltage drop when the apparatus is filled with different SF6-N2 mixtures.

  4. Proposal to negotiate two contracts, without competitive tendering, for the supply and the repair of compressors for the LHC 18 kW helium refrigeration plants

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    Proposal to negotiate two contracts, without competitive tendering, for the supply and the repair of compressors for the LHC 18 kW helium refrigeration plants

  5. Size dependent structural and magnetic properties of Al substituted Co–Mg ferrites synthesized by the sol–gel auto-combustion method

    SciTech Connect (OSTI)

    Ahmad, Imran, E-mail: imraan77@yahoo.com [Department of Physics, Bahauddin Zakariya University, Multan 60800 (Pakistan); Abbas, Tahir [Centre for Solid State Physics, University of the Punjab, Lahore 54560 (Pakistan); Ziya, A.B. [Department of Physics, Bahauddin Zakariya University, Multan 60800 (Pakistan); Abbas, Ghazanfar [Department of Physics, Comsats Institute of Information Technology, Islamabad 44000 (Pakistan); Maqsood, Asghari [Centre for Emerging Sciences, Engineering and Technology (CESET) , I 10/3, Islamabad 45320 (Pakistan)

    2014-04-01T23:59:59.000Z

    Highlights: • Well-crystalline Co{sub 0.7}Mg{sub 0.3}AlFeO{sub 4} nanoparticles with small grain size were obtained. • The approach is sol–gel auto-combustion technique for obtained nanoparticles. • The prepared Co{sub 0.7}Mg{sub 0.3}AlFeO{sub 4} ferrites are decent soft materials with low coercivity. • The minor decrease in lattice parameter with increase of temperature was observed. - Abstract: Single phased nanocrystalline Co{sub 0.7}Mg{sub 0.3}FeAlO{sub 4} ferrites having low coercivity were synthesized by the sol–gel auto-combustion route. The subsequent powder materials were sintered in a temperature range of 800–1200 °C for 2 h. The effects of sintering temperatures on the structure, morphology and magnetic properties of the prepared soft magnetic material were studied. X-ray diffractometer (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), and magnetic property measurement system (MPMS) were used to characterize the samples. X-ray diffraction analysis confirmed a single-phase cubic spinel structure and ruled out the presence of impurities like hematite. The higher sintering temperatures have caused in enhanced mark of crystallinity and bigger average grain size of the nanocrystals. A slight decrease in lattice parameters was noticed with a rise of grain size. Magnetic measurements revealed that grain size increase led to a decrease in the coercivity and, in difference, an increase in the saturation magnetization.

  6. DNA Repair Biomarkers Predict Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer

    SciTech Connect (OSTI)

    Alexander, Brian M., E-mail: bmalexander@lroc.harvard.edu [Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (United States); Wang Xiaozhe [On-Q-ity, Inc., Waltham, Massachusetts (United States); Niemierko, Andrzej [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Weaver, David T. [On-Q-ity, Inc., Waltham, Massachusetts (United States); Mak, Raymond H. [Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (United States); Roof, Kevin S. [Southeast Radiation Oncology, Charlotte, North Carolina (United States); Fidias, Panagiotis [Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts (United States); Wain, John [Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts (United States); Choi, Noah C. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)

    2012-05-01T23:59:59.000Z

    Purpose: The addition of neoadjuvant chemoradiotherapy prior to surgical resection for esophageal cancer has improved clinical outcomes in some trials. Pathologic complete response (pCR) following neoadjuvant therapy is associated with better clinical outcome in these patients, but only 22% to 40% of patients achieve pCR. Because both chemotherapy and radiotherapy act by inducing DNA damage, we analyzed proteins selected from multiple DNA repair pathways, using quantitative immunohistochemistry coupled with a digital pathology platform, as possible biomarkers of treatment response and clinical outcome. Methods and Materials: We identified 79 patients diagnosed with esophageal cancer between October 1994 and September 2002, with biopsy tissue available, who underwent neoadjuvant chemoradiotherapy prior to surgery at the Massachusetts General Hospital and used their archived, formalin-fixed, paraffin-embedded biopsy samples to create tissue microarrays (TMA). TMA sections were stained using antibodies against proteins in various DNA repair pathways including XPF, FANCD2, PAR, MLH1, PARP1, and phosphorylated MAPKAP kinase 2 (pMK2). Stained TMA slides were evaluated using machine-based image analysis, and scoring incorporated both the intensity and the quantity of positive tumor nuclei. Biomarker scores and clinical data were assessed for correlations with clinical outcome. Results: Higher scores for MLH1 (p = 0.018) and lower scores for FANCD2 (p = 0.037) were associated with pathologic response to neoadjuvant chemoradiation on multivariable analysis. Staining of MLH1, PARP1, XPF, and PAR was associated with recurrence-free survival, and staining of PARP1 and FANCD2 was associated with overall survival on multivariable analysis. Conclusions: DNA repair proteins analyzed by immunohistochemistry may be useful as predictive markers for response to neoadjuvant chemoradiotherapy in patients with esophageal cancer. These results are hypothesis generating and need confirmation in an independent data set.

  7. JAG Tearing Technique with Radiofrequency Guide Wire for Aortic Fenestration in Thoracic Endovascular Aneurysm Repair

    SciTech Connect (OSTI)

    Ricci, Carmelo [Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Radiologia Interventistica (Italy); Ceccherini, Claudio, E-mail: claudiocec@hotmail.it; Leonini, Sara [Radiologia Universitaria, Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte (Italy); Cini, Marco; Vigni, Francesco [Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Radiologia Interventistica (Italy); Neri, Eugenio; Tucci, Enrico; Benvenuti, Antonio; Tommasino, Giulio; Sassi, Carlo [Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Chirurgia dell'Aorta Toracica (Italy)

    2012-02-15T23:59:59.000Z

    An innovative approach, the JAG tearing technique, was performed during thoracic endovascular aneurysm repair in a patient with previous surgical replacement of the ascending aorta with a residual uncomplicated type B aortic dissection who developed an aneurysm of the descending thoracic aorta with its lumen divided in two parts by an intimal flap. The proximal landing zone was suitable to place a thoracic stent graft. The distal landing zone was created by cutting the intimal flap in the distal third of the descending thoracic aorta with a radiofrequency guide wire and intravascular ultrasound catheter.

  8. Endovascular Stent-Graft Repair as a Late Secondary Procedure After Previous Aortic Grafts

    SciTech Connect (OSTI)

    Matsagas, Miltiadis I. [School of Medicine, University of Ioannina, Department of Surgery - Vascular Surgery Unit (Greece)], E-mail: mimats@cc.uoi.gr; Anagnostopoulos, Constantine E. [School of Medicine, University of Ioannina, Department of Cardiothoracic Surgery (Greece); Papakostas, John C. [School of Medicine, University of Ioannina, Department of Surgery - Vascular Surgery Unit (Greece); DeRose, Joseph J. [St. Luke's-Roosevelt Hospital, Columbia University, Department of Cardiothoracic Surgery (United States); Siminelakis, Stavros [School of Medicine, University of Ioannina, Department of Cardiothoracic Surgery (Greece); Katsouras, Christos S. [School of Medicine, University of Ioannina, Department of Cardiology (Greece); Toumpoulis, Ioannis K.; Drossos, George E. [School of Medicine, University of Ioannina, Department of Cardiothoracic Surgery (Greece); Michalis, Lampros K. [School of Medicine, University of Ioannina, Department of Cardiology (Greece)

    2006-08-15T23:59:59.000Z

    Thoracic and abdominal aortic endovascular procedures as alternatives to aortic reoperations were studied in three different cases. An anastomotic aneurysm after previous thoracic aortic graft for coarctation, a second-stage elephant trunk repair (descending thoracic aortic aneurysm), and a secondary aneurysm proximal to a previous abdominal aortic graft were successfully treated with endovascular stent-grafts. During the follow-up period no lethal events or major aortic or graft-related complications were observed, except a type II endoleak in the anastomotic aortic aneurysm case. An endovascular stent-graft can be safely deployed into a previously implanted vascular graft, avoiding repeat surgery.

  9. Superfund record of decision (EPA Region 4): Savannah River Site (USDOE), Motor Shops Seepage Basin (716-A), Aiken, SC, June 26, 1998

    SciTech Connect (OSTI)

    NONE

    1998-10-01T23:59:59.000Z

    The Motor Shops Seepage Basin (716-A) (MSSB) is listed as a Resource Conservation and Recovery Act (RCRA) 3004(u) solid waste management unit/Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) unit in Appendix C of the Federal Facility Agreement (FFA) (FFA 1993) for the Savannah River Site (SRS), in Aiken, South Carolina. The selected alternative was developed in accordance with CERCLA, as amended, and to the extent practicable, the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The selected remedy for MSSB is No Action. Investigation of this operable unit was performed to determine if hazardous substances had been released to the environment. The Baseline Risk Assessment indicated that there were no significant releases to the environment. Therefore, it appears that either there were no significant discharges of hazardous materials to the seepage basin or natural remediation processes (i.e., bioremediation) have reduced the levels of hazardous materials to the extent that they no longer pose risk to human health or the environment. The Baseline Risk Assessment considered both the future residential and future industrial land use scenarios. Benzo(a)pyrene was the only preliminary constituent of concern (human health) detected in the soil at MSSB. Benzo(a)pyrene was detected only in the top foot of soil at levels which give risk values greater than 1 {times} 16{sup {minus}6} (but less than 1 {times} 10{sup {minus}4}) for the future adult/child resident. Further uncertainty analysis indicated that benzo(a)pyrene should not be considered a constituent of concern for the MSSB due to: (1) low frequency of detection; (2) unit history that strongly suggests it came from an adjacent source; and (3) conservative methodology was utilized in the risk assessment. No ecological or contaminant migration constituents of concern were identified at this unit. Therefore, No Action is the appropriate remedy and a five year ROD review will not be required. The South Carolina Department of Health and Environmental Control has modified the SRS RCRA permit to incorporate the No Action remedy.

  10. Dofasco`s No. 4 blast furnace hearth breakout, repair and rescue

    SciTech Connect (OSTI)

    Donaldson, R.J.; Fischer, A.J.; Sharp, R.M.; Stothart, D.W. [Dofasco Inc., Hamilton, Ontario (Canada)

    1995-12-01T23:59:59.000Z

    On May 5, 1994, after producing 9.5 million metric tons of iron, Dofasco`s No. 4 Blast Furnace experienced a hearth breakout 250 millimeters below the west taphole. The hot metal spill caused a fire resulting in severe damage and 33 days of lost production. During a 26-day period, electrical wiring, water drainage systems and both tapholes were repaired. Recovery from an unprepared furnace stop of this length, with the deadman depleted is difficult. To aid with the rescue Hoogovens-designed oxygen/fuel lances were commissioned. The furnace recovery began with a lance in each taphole and all tuyeres plugged. Six days after startup the furnace was casting into torpedo cars, and after nine days operation had returned to normal. This incident prompted Dofasco to expand the hearth monitoring system to detect and prevent similar occurrences. During the repair, 203 new thermocouples were installed in the hearth, concentrating on the tapholes and elephant foot areas. These thermocouples were installed at various depths and locations to allow heat flux calculations. This hearth monitoring system has already identified other problem areas and provided valuable information about hearth drainage patterns. This information has allowed them to develop control strategies to manage localized problem areas.

  11. Percutaneous Stent-Graft Repair of a Mycotic Pulmonary Artery Pseudoaneurysm

    SciTech Connect (OSTI)

    Chou Meichun; Liang Hueilung, E-mail: hlliang@isca.vghks.gov.tw; Pan Huayban; Yang Chienfang [Kaohsiung Veterans General Hospital, Department of Radiology (China)

    2006-10-15T23:59:59.000Z

    Ruptured mycotic pulmonary pseudoaneurysm is a lethal complication. Emergent surgical repair is usually recommended, but still associated with a high mortality rate. We present a patient in whom mycotic pulmonary pseudoaneurysm was a complication after surgical lobectomy 2 weeks earlier. This patient had suffered from repeated massive hemoptysis. After emergent surgical repair of the ruptured pulmonary artery stump, another episode of massive hemorrhage occurred. The pulmonary arteriogram revealed a segmental stenosis and a large, wide-necked, lobulated pseudoaneurysm at the left proximal pulmonary artery. We deployed a balloon-expandable stent-graft (48 mm in length mounted on a 12 mm x 40 mm angioplasty balloon) across the stenotic segment and the neck of the pulmonary pseudoaneurysm. Hemostasis was achieved immediately and, under a 4-week antibiotic treatment, patient was transferred to a local hospital for medical care. This case report demonstrates the benefit of minimally invasive endovascular therapy in a critically ill patient. A literature review of the etiology and management of mycotic pulmonary pseudoaneurysm is included.

  12. Operational results of shaft repair by installing stave type cooler at Kimitsu Nos. 3 and 4 blast furnaces

    SciTech Connect (OSTI)

    Oda, Hiroshi; Amano, Shigeru; Sakamoto, Aiichiro; Anzai, Osamu [Nippon Steel Corp., Kimitsu, Chiba (Japan). Kimitsu Works; Nakagome, Michiru; Kuze, Toshisuke [Nippon Steel Corp., Futtsu, Chiba (Japan); Imuta, Akira [Nippon Steel Corp., Tokyo (Japan). Plant and Machinery Div.

    1997-12-31T23:59:59.000Z

    Nos. 3 and 4 blast furnaces in Nippon Steel Corporation Kimitsu Works were both initially fitted with cooling plate systems. With the aging of each furnace, the damage to their respective inner-shaft profiles had become serious. Thus, in order to prevent operational change and prolong the furnace life, the inner-shaft profile of each furnace was repaired by replacing the former cooling plate system with the stave type cooler during the two-week-shutdowns. With this repair, stability of burden descent and gas flow near the wall part of the furnace have been achieved. Thus the prolongation of the furnace life is naturally expected.

  13. Inhibition of X-ray-induced potentially lethal damage (PLD) repair in aerobic plateau-phase Chinese hamster cells by misonidazole

    SciTech Connect (OSTI)

    Brown, D.M.

    1984-01-01T23:59:59.000Z

    The effect of the 2-nitroimidazole radiosensitizer misonidazole (MISO) and the hydrophilic analog SR-2508 on the repair of X-ray-induced potentially lethal damage (PLD) was studied in plateau-phase Chinese Hamster ovary (HA-1) cells. It was found that although MISO does not radiosensitize aerobic cells, it inhibits the repair of PLD. However, under hypoxic conditions, MISO has no effect on PLD repair. The major portion of the inhibition of PLD repair in aerobic cells requires the presence of MISO only during irradiation; little or no additional inhibition occurs when MISO is present during the postirradiation repair period. Also, treatment of aerobic cells with 5 mM MISO for either 5 or 30 min prior to irradiation is equally inhibitory. This suggests that the presence of MISO in some way modifies the initial lesion under aerobic conditions since it does not increase cell killing as determined by immediate plating but inhibits subsequent repair. The inhibition is concentration dependent; 0.5 mM MISO inhibits PLD repair by one-half while 5-10 mM totally inhibits the repair measured 6 hr postirradiation. This phenomenon suggests that radiosensitization of tissue in vivo by MISO and other 2-nitroimidazoles may not be unequivocal proof of the presence of hypoxic cells.

  14. Subj: Educational and General (E&G) Facility Support Provide an overview of Facility Operations, Maintenance, Repair and Renovation and Space

    E-Print Network [OSTI]

    support, and, preventive and unscheduled maintenance of all building systems, with the exception of BAS Operations, Maintenance, Repair and Renovation and Space Management Procedures and Practices. KEY DEFINITIONS chambers, fume hoods, fixed seating, etc. are normally considered part of the building. Maintenance, repair

  15. Performance and Impact from Duct Repair and Ventilation Modifications of Two Newly Constructed Manufactured Houses Located in a Hot and Humid Climate

    E-Print Network [OSTI]

    Withers, C.; Moyer, N.; Chasar, D.; Chandra, S.

    2002-01-01T23:59:59.000Z

    airtightness was adjusted until it was the same in each house, and duct leaks were sealed so that the ducts were tight and there was equal tightness in both houses. A ventilation system was also added at the same time of duct repair. Duct repair...

  16. Shopping is Work: An Institutional Ethnography of Grocery Shopping

    E-Print Network [OSTI]

    Koch, Shelley L.

    2009-04-21T23:59:59.000Z

    based sometimes what?s on sale and we have a deep freeze so sometimes if meat and things like that are on sale then I buy more of that kind of thing then go by what is in the deep freeze. [Do you make an inventory?] No, I just kind of remember (Lisa...

  17. Optimization Online - Job-Shop Scheduling in a Body Shop

    E-Print Network [OSTI]

    Joachim Schauer

    2011-03-24T23:59:59.000Z

    Mar 24, 2011 ... This problem arises from the industrial application of welding in a car body production line, where possible collisions between industrial robots ...

  18. Development Shop | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisitingContract Management FermiDavid Turner David3DepthDetectingNERSC Helps3

  19. Shop Request - 88-Inch Cyclotron

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomelandMultivariate Metal-Organic

  20. Original Full Length Article Inkjet-based biopatterning of SDF-1 augments BMP-2-induced repair of

    E-Print Network [OSTI]

    Weiss, Lee E.

    Original Full Length Article Inkjet-based biopatterning of SDF-1 augments BMP-2-induced repair Biopatterning BMP-2 SDF-1 TGF-1 Background: A major problem in craniofacial surgery is non-healing bone defects-derived factor-1 (SDF-1), transforming growth factor-1 (TGF-1), or co-therapies thereof. We tested the hypothesis

  1. The Effect of Debris on Collector Optics, its Mitigation and Repair: Next-Step a Gaseous Sn EUV DPP Source

    E-Print Network [OSTI]

    Spila, Timothy P.

    The Effect of Debris on Collector Optics, its Mitigation and Repair: Next-Step a Gaseous Sn EUV DPP to advanced fuel plasma EUV sources is collector lifetime. The Illinois Debris-mitigation EUV Applications based on this work. Keywords: EUV source, debris, optics, collector lifetime, mitigation, plasma

  2. Image-Guided Techniques Improve the Short-term Outcome of Autologous Osteochondral Cartilage Repair Surgeries -An

    E-Print Network [OSTI]

    Stewart, James

    Image-Guided Techniques Improve the Short-term Outcome of Autologous Osteochondral Cartilage Repair and deliver osteochondral grafts remains problematic. We investigated whether image-guided methods (optically-guided and template-guided) can improve the outcome of mo- saic arthroplasty procedures. Methods: Fifteen sheep were

  3. Surgical technique, using skin, for repair of simultaneously ruptured anterior cruciate and medial collateral ligaments of the canine femorotibial articulation

    E-Print Network [OSTI]

    Chastain, Jamie Neal

    1959-01-01T23:59:59.000Z

    Agricultural and Mechanical College of Texan In Partial Fulfillnent of the !Iequireaents for the Degree Meeter of Science in Veterinary Medicine and Surgery by Janie Neal Chaetain January 1&359 SURGICAL TECHNI((UE ~ USIN'G SKIN ~ FOR REPAIR...

  4. Diet-dependent survival of protein repair-deficient miceB Christine E. Farrar, Steven ClarkeT

    E-Print Network [OSTI]

    Clarke, Steven

    Diet-dependent survival of protein repair-deficient miceB Christine E. Farrar, Steven Clarke, and mice lacking this enzyme accumulate damaged proteins in multiple tissues, die at an early age from and in vivo [1­7]. Mice lacking the enzyme (Pcmt1À/À mice) accu- mulate damaged proteins in multiple tissues

  5. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions

    SciTech Connect (OSTI)

    Zafar, Faria; Seidler, Sara B.; Kronenberg, Amy; Schild, David; Wiese, Claudia

    2010-06-29T23:59:59.000Z

    To test the contribution of homologous recombinational repair (HRR) in repairing DNA damaged sites induced by high-energy iron ions, we used: (1) HRR-deficient rodent cells carrying a deletion in the RAD51D gene and (2) syngeneic human cells impaired for HRR by RAD51D or RAD51 knockdown using RNA interference. We show that in response to iron ions, HRR contributes to cell survival in rodent cells, and that HRR-deficiency abrogates RAD51 foci formation. Complementation of the HRR defect by human RAD51D rescues both enhanced cytotoxicity and RAD51 foci formation. For human cells irradiated with iron ions, cell survival is decreased, and, in p53 mutant cells, the levels of mutagenesis are increased when HRR is impaired. Human cells synchronized in S phase exhibit more pronounced resistance to iron ions as compared with cells in G1 phase, and this increase in radioresistance is diminished by RAD51 knockdown. These results implicate a role for RAD51-mediated DNA repair (i.e. HRR) in removing a fraction of clustered lesions induced by charged particle irradiation. Our results are the first to directly show the requirement for an intact HRR pathway in human cells in ensuring DNA repair and cell survival in response to high-energy high LET radiation.

  6. A review of "To Repair the Ruins: Reading Milton" edited by Mary C. Fenton and Louis Schwartz

    E-Print Network [OSTI]

    Welch, Anthony

    2013-01-01T23:59:59.000Z

    that deserve the attention he gives them. Mary C. Fenton and Louis Schwartz, eds. To Repair the Ruins: Reading Milton. Pittsburgh: Duquesne University Press, #18;#17;#16;#18;. xii + #1;#30; pp. + #18;#18; illus. $#14;#15;.#17;#17;. Review by #8...

  7. Design structure for in-system redundant array repair in integrated circuits

    DOE Patents [OSTI]

    Bright, Arthur A.; Crumley, Paul G.; Dombrowa, Marc; Douskey, Steven M.; Haring, Rudolf A.; Oakland, Steven F.; Quellette, Michael R.; Strissel, Scott A.

    2008-11-25T23:59:59.000Z

    A design structure for repairing an integrated circuit during operation of the integrated circuit. The integrated circuit comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The design structure provides the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The design structure further passes the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.

  8. Designer's guidebook for first wall/blanket/shield assembly, maintenance, and repair

    SciTech Connect (OSTI)

    Not Available

    1983-12-30T23:59:59.000Z

    This is the initial issue of the guidebook. Since a guidebook of this type must incorporate information concerning a wide range of subjects, much additional data will eventually be included. The guidebook will document, in summary and easily referenceable form, data, designs, design concepts, design guidelines and background information useful to the FWBS and to the Maintenance System designer. In providing guidelines for the AMR of the FWBS, the guidebook must, of necessity, include guidelines for all aspects of maintenance associated with the FWBS. These include most maintenance operations within the reactor room necessary to gain access, identify faults, and handle equipment related to FWBS maintenance. In addition, the guidelines include those required to define facility requirements for handling and repair of FWBS and related reactor components external to the reactor room. Particular emphasis is given to remote maintenance design and operations.

  9. Engineering Endostatin-Producing Cartilaginous Constructs for Cartilage Repair Using Nonviral Transfection of Chondrocyte-Seeded and Mesenchymal-Stem-Cell-Seeded Collagen Scaffolds

    E-Print Network [OSTI]

    Jeng, Lily

    Although there is widespread recognition of the importance of angiogenesis in tissue repair, there is little work on the inhibition of angiogenesis in the context of tissue engineering of naturally avascular tissues, like ...

  10. Disrupted G{sub 1} to S phase clearance via cyclin signaling impairs liver tissue repair in thioacetamide-treated type 1 diabetic rats

    SciTech Connect (OSTI)

    Devi, Sachin S. [Department of Toxicology, School of Pharmacy, College of Health Sciences, University of Louisiana at Monroe, 700 University Avenue, Sugar Hall no. 306, Monroe, LA 71209-0470 (United States); Mehendale, Harihara M. [Department of Toxicology, School of Pharmacy, College of Health Sciences, University of Louisiana at Monroe, 700 University Avenue, Sugar Hall no. 306, Monroe, LA 71209-0470 (United States)]. E-mail: mehendale@ulm.edu

    2005-09-01T23:59:59.000Z

    Previously we reported that a nonlethal dose of thioacetamide (TA, 300 mg/kg) causes 90% mortality in type 1 diabetic (DB) rats because of irreversible acute liver injury owing to inhibited hepatic tissue repair, primarily due to blockage of G{sub 0} to S phase progression of cell division cycle. On the other hand, DB rats receiving 30 mg TA/kg exhibited equal initial liver injury and delayed tissue repair compared to nondiabetic (NDB) rats receiving 300 mg TA/kg, resulting in a delay in recovery from liver injury and survival. The objective of the present study was to test the hypothesis that impaired cyclin-regulated progression of G{sub 1} to S phase of the cell cycle may explain inhibited liver tissue repair, hepatic failure, and death, contrasted with delayed liver tissue repair but survival observed in the DB rats receiving 300 in contrast to 30 mg TA/kg. In the TA-treated NDB rats sustained MAPKs and cyclin expression resulted in higher phosphorylation of retinoblastoma (pRb), explaining prompt tissue repair and survival. In contrast, DB rats receiving the same dose of TA (300 mg/kg) exhibited suppressed MAPKs and cyclin expression that led to inhibition of pRb, inhibited tissue repair, and death. On the other hand, DB rats receiving 30 mg TA/kg exhibited delayed up regulation of MAPK signaling that delayed the expression of CD1 and pRb, explaining delayed stimulation of tissue repair observed in this group. In conclusion, the hepatotoxicant TA has a dose-dependent adverse effect on cyclin-regulated pRb signaling: the lower dose causes a recoverable delay, whereas the higher dose inhibits it with corresponding effect on the ultimate outcomes on hepatic tissue repair; this dose-dependent adverse effect is substantially shifted to the left of the dose response curve in diabetes.

  11. The Preclose Technique in Percutaneous Endovascular Aortic Repair: A Systematic Literature Review and Meta-analysis

    SciTech Connect (OSTI)

    Jaffan, Abdel Aziz A., E-mail: aajaffan@gmail.com [Emory University School of Medicine, Division of Interventional Radiology and Image-Guided Medicine, Department of Radiology (United States); Prince, Ethan A., E-mail: eprince@lifespan.org [Warren Alpert Medical School of Brown University, Rhode Island Hospital, Section of Vascular and Interventional Radiology, Department of Diagnostic Imaging (United States); Hampson, Christopher O., E-mail: christopherohampson@gmail.com [Mercy Hospital (United States); Murphy, Timothy P., E-mail: tmurphy@lifespan.org [Warren Alpert Medical School of Brown University, Rhode Island Hospital, Section of Vascular and Interventional Radiology, Department of Diagnostic Imaging (United States)

    2013-06-15T23:59:59.000Z

    Purpose. To establish the efficacy and safety of the preclose technique in total percutaneous endovascular aortic repair (PEVAR).MethodsA systematic literature search of Medline database was conducted for series on PEVAR published between January 1999 and January 2012.ResultsThirty-six articles comprising 2,257 patients and 3,606 arterial accesses were included. Anatomical criteria used to exclude patients from undergoing PEVAR were not uniform across all series. The technical success rate was 94 % per arterial access. Failure was unilateral in the majority (93 %) of the 133 failed PEVAR cases. The groin complication rate in PEVAR was 3.6 %; a minority (1.6 %) of these groin complications required open surgery. The groin complication rate in failed PEVAR cases converted to groin cutdown was 6.1 %. A significantly higher technical success rate was achieved when arterial access was performed via ultrasound guidance. Technical failure rate was significantly higher with larger sheath size ({>=}20F). Conclusion. The preclose technique in PEVAR has a high technical success rate and a low groin complication rate. Technical success tends to increase with ultrasound-guided arterial access and decrease with larger access. When failure occurs, it is unilateral in the majority of cases, and conversion to surgical cutdown does not appear to increase the operative risk.

  12. Evaluating indoor exposure modeling alternatives for LCA: A case study in the vehicle repair industry

    SciTech Connect (OSTI)

    Demou, Evangelia; Hellweg, Stefanie; Wilson, Michael P.; Hammond, S. Katharine; McKone, Thomas E.

    2009-05-01T23:59:59.000Z

    We evaluated three exposure models with data obtained from measurements among workers who use"aerosol" solvent products in the vehicle repair industry and with field experiments using these products to simulate the same exposure conditions. The three exposure models were the: 1) homogeneously-mixed-one-box model, 2) multi-zone model, and 3) eddy-diffusion model. Temporally differentiated real-time breathing zone volatile organic compound (VOC) concentration measurements, integrated far-field area samples, and simulated experiments were used in estimating parameters, such as emission rates, diffusivity, and near-field dimensions. We assessed differences in model input requirements and their efficacy for predictive modeling. The One-box model was not able to resemble the temporal profile of exposure concentrations, but it performed well concerning time-weighted exposure over extended time periods. However, this model required an adjustment for spatial concentration gradients. Multi-zone models and diffusion-models may solve this problem. However, we found that the reliable use of both these models requires extensive field data to appropriately define pivotal parameters such as diffusivity or near-field dimensions. We conclude that it is difficult to apply these models for predicting VOC exposures in the workplace. However, for comparative exposure scenarios in life-cycle assessment they may be useful.

  13. Connecting with the Auto Industry

    Broader source: Energy.gov [DOE]

    Under Secretary Steve Koonin reflects on his experience at the Center for Automotive Research's annual Management Briefing Seminar.

  14. auto | OpenEI Community

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty Edit withTianlinPapersWindey Wind GeneratingZhongshengZiboZongshenask queries Home

  15. Byers Auto | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty EditCalifornia:Power LP Biomass Facility JumpBurleigh County,BuschButteBye Energy

  16. OpenEI Community - auto

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation, searchOfRoseConcernsCompany Oil and GasOff thedrivingGiven

  17. The Impact of Individual In Vivo Repair of DNA Double-Strand Breaks on Oral Mucositis in Adjuvant Radiotherapy of Head-and-Neck Cancer

    SciTech Connect (OSTI)

    Fleckenstein, Jochen, E-mail: rajfle@uks.eu [Department of Radiotherapy and Radiation Oncology, Saarland University Medical School, Homburg (Germany); Kuehne, Martin; Seegmueller, Katharina; Derschang, Sarah; Melchior, Patrick [Department of Radiotherapy and Radiation Oncology, Saarland University Medical School, Homburg (Germany); Graeber, Stefan [Institute for Medical Biometry, Epidemiology und Medical Informatics (IMBEI), Saarland University Medical School, Homburg (Germany); Fricke, Andreas; Ruebe, Claudia E.; Ruebe, Christian [Department of Radiotherapy and Radiation Oncology, Saarland University Medical School, Homburg (Germany)

    2011-12-01T23:59:59.000Z

    Purpose: To evaluate the impact of individual in vivo DNA double-strand break (DSB) repair capacity on the incidence of severe oral mucositis in patients with head-and-neck cancer undergoing adjuvant radiotherapy (RT) or radiochemotherapy (RCT). Patients and Methods: Thirty-one patients with resected head-and-neck cancer undergoing adjuvant RT or RCT were examined. Patients underwent RT of the primary tumor site and locoregional lymph nodes with a total dose of 60-66 Gy (single dose 2 Gy, five fractions per week). Chemotherapy consisted of two cycles of cisplatin and 5-fluorouracil. To assess DSB repair, {gamma}-H2AX foci in blood lymphocytes were quantified before and 0.5 h, 2.5 h, 5 h, and 24 h after in vivo radiation exposure (the first fraction of RT). World Health Organization scores for oral mucositis were documented weekly and correlated with DSB repair. Results: Sixteen patients received RT alone; 15 patients received RCT. In patients who developed Grade {>=} 3 mucositis (n = 18) the amount of unrepaired DSBs 24 h after radiation exposure and DSB repair half-times did not differ significantly from patients with Grade {<=}2 mucositis (n = 13). Patients with a proportion of unrepaired DSBs after 24 h higher than the mean value + one standard deviation had an increased incidence of severe oral mucositis. Conclusions: Evaluation of in vivo DSB repair by determination of {gamma}-H2AX foci loss is feasible in clinical practice and allows identification of patients with impaired DSB repair. The incidence of oral mucositis is not closely correlated with DSB repair under the evaluated conditions.

  18. Identification of Intrinsic Order and Disorder in the DNA Repair Protein XPA

    SciTech Connect (OSTI)

    Iakoucheva, Lilia M.; Kimzey, Amy L.; Masselon, Christophe D.; Bruce, James E.; Garner, Ethan C.; Brown, Celeste J.; Dunker, A. K.; Smith, Richard D.; Ackerman, Eric J.

    2001-03-01T23:59:59.000Z

    The damage recognition protein XPA is required to recognize a wide variety of bulky lesions during nucleotide excision repair (NER). Independent NMR solution structures of a human XPA protein (hXPA) fragment comprising approximately one-third of the full-length protein, the minimal DNA-binding domain (MBD), revealed that ~30% of the molecule was structurally disordered. To better characterize structural features of XPA, we performed time-resolved trypsin proteolysis on active, full-length recombinant Xenopus XPA protein (xXPA). The resulting proteolytic fragments were analyzed by electrospray ionization interface coupled to a Fourier transform ion cyclotron resonance (ESI-FTICR) mass spectrometry, SDS-polyacrylamide gel electrophoresis (PAGE), and selected N-terminal sequence determinations. The mass spectrum of the full-length xXPA was consistent with the predicted sequence, 30922.02 vs. 30922.45 Da; respectively. Moreover, the mass spectrometric data allowed the assignment of multiple xXPA fragments not resolvable by SDS PAGE. Full-length xXPA exhibited aberrant mobility on SDS-PAGE with an apparent MW of ~40 kDa. To test predictions that a Glu-rich region (E70-E76) or other local regions of high charge were responsible for this ~40% aberrant SDS-PAGE mobility, the MW's of partial proteolytic fragments from ~5 to 25 kDa precisely determined by ESI-FTICR MS were correlated with their gel positions. Surprisingly, all tested partial tryptic fragments within this size-range exhibited 10-42% divergence between calculated MW and that estimated by SDS-PAGE, thus indicating the origin of anomalous migration of XPA is not localized. The computer program Predictor of Natural Disordered Regions (PONDR) correctly identified several regions of xXPA either sensitive or resistant to partial proteolysis, thereby indicating that disorder in XPA shares sequence features with other well-characterized intrinsically unstructured proteins.

  19. Environmental Assessment and Finding of No Significant Impact: Pond B Dam Repair Project at the Savannah River Site

    SciTech Connect (OSTI)

    N /A

    1999-09-27T23:59:59.000Z

    The Department of Energy (DOE) has prepared an environmental assessment (EA) (DOE/EA-1285) for the proposed repair of the Pond B dam at the Savannah River Site (SRS), located near Aiken, South Carolina. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, the preparation of an environmental impact statement (EIS) is not required, and DOE is issuing this Finding of No Significant Impact (FONSI) and Floodplain Statement of Findings.

  20. Structural and ambient/sub-ambient temperature magnetic properties of Er-substituted cobalt-ferrites synthesized by sol-gel assisted auto-combustion method

    SciTech Connect (OSTI)

    Prathapani, Sateesh [School of Engineering Sciences and Technology, University of Hyderabad, Hyderabad 500046 (India); Department of Metallurgical Engineering and Materials Science, IIT-Bombay, Mumbai 400076 (India); Jayaraman, Tanjore V., E-mail: ddas@uohyd.ernet.in, E-mail: tvjayaraman@gmail.com [Department of Mechanical and Materials Engineering, University of Nebraska, Lincoln, Nebraska 68588 (United States); Varaprasadarao, Eswara K. [Department of Metallurgical Engineering and Materials Science, IIT-Bombay, Mumbai 400076 (India); Das, Dibakar, E-mail: ddas@uohyd.ernet.in, E-mail: tvjayaraman@gmail.com [School of Engineering Sciences and Technology, University of Hyderabad, Hyderabad 500046 (India)

    2014-07-14T23:59:59.000Z

    Er-substituted cobalt-ferrites CoFe{sub 2?x}Er{sub x}O{sub 4} (0???x???0.04) were synthesized by sol-gel assisted auto-combustion method. The precursor powders were calcined at 673–873?K for 4?h, subsequently pressed into pellets and sintered at 1273?K for 4?h. X-ray diffraction (XRD) confirmed the presence of the spinel phase for all the compositions and, additional orthoferrite phase for higher compositions (x?=?0.03 and 0.04). The XRD spectra and the Transmission Electron Microscopy micrographs indicate that the nanocrystalline particulates of the Er-substituted cobalt ferrites have crystallite size of ?120–200?nm. The magnetization curves show an increase in saturation magnetization (M{sub S}) and coercivity (H{sub C}) for Er-substituted cobalt-ferrites at sub-ambient temperatures. M{sub S} for CoFe{sub 2}O{sub 4}, CoFe{sub 0.99}Er{sub 0.01}O{sub 4}, CoFe{sub 0.98}Er{sub 0.02}O{sub 4}, and CoFe{sub 0.97}Er{sub 0.03}O{sub 4} peak at 89.7?Am{sup 2}/kg, 89.3?Am{sup 2}/kg, 88.8?Am{sup 2}/kg, and 87.1?Am{sup 2}/kg, respectively, at a sub-ambient temperature of ?150?K. H{sub C} substantially increases with decrease in temperature for all the compositions, while it peaks at x?=?0.01?0.02 at all temperatures. The combination of Er content—x???0.02 and the temperature—?5?K provides the maximum H{sub C}???984?kA/m. Er-substituted cobalt-ferrites have higher cubic anisotropy constant, K{sub 1}, compared to pure cobalt-ferrite at ambient/sub-ambient temperatures. K{sub 1} gradually increases for all compositions in the temperature decreasing from 300 to 100?K. While K{sub 1} peaks at ?150?K for pure cobalt-ferrite, it peaks at ?50?K for CoFe{sub 0.99}Er{sub 0.01}O{sub 4}, CoFe{sub 0.98}Er{sub 0.02}O{sub 4}, and CoFe{sub 0.96}Er{sub 0.04}O{sub 4}. The M{sub S} (?88.7?Am{sup 2}/kg), at 5?K, for Er substituted cobalt-ferrite is close to the highest values reported for Sm and Gd substituted cobalt-ferrites. The M{sub S} (?83.5?Am{sup 2}/kg) at 300?K for Er-substituted cobalt-ferrite is the highest among the lanthanide series element substituted cobalt-ferrites. The H{sub C} (at 5?K) for Er substituted cobalt-ferrite is close to the highest values observed for La, Ce, Nd, Sm, and Gd substituted cobalt-ferrites.

  1. RADIATION SENSITIVITY & PROCESSING OF DNA DAMAGE FOLLOWING LOW DOSES OF GAMMA-RAY ALPHA PARTICLES & HZE IRRADIATION OF NORMAL DSB REPAIR DEFICIENT CELLS

    SciTech Connect (OSTI)

    O'Neil, Peter

    2009-05-15T23:59:59.000Z

    Non-homologous end joining (NHEJ) predominates in the repair of DNA double strand breaks (DSB) over homologous recombination (HR). NHEJ occurs throughout the cell cycle whereas HR occurs in late S/G2 due to the requirement of a sister chromatid (Rothkamm et al, Mol Cell Biol 23 5706-15 [2003]). To date evidence obtained with DSB repair deficient cells using pulsed-field gel electrophoresis has revealed the major pathway throughout all phases of the cell cycle for processing high dose induced DSBs is NHEJ (Wang et al, Oncogene 20 2212-24 (2001); Pluth et al, Cancer Res. 61 2649-55 [2001]). These findings however were obtained at high doses when on average >> 20-30 DSBs are formed per cell. The contribution of the repair pathways (NHEJ and HR) induced in response to DNA damage during the various phases of the cell cycle may depend upon the dose (the level of initial DSBs) especially since low levels of DSBs are induced at low dose. To date, low dose studies using NHEJ and HR deficient mutants have not been carried out to address this important question with radiations of different quality. The work presented here leads us to suggest that HR plays a relatively minor role in the repair of radiation-induced prompt DSBs. SSBs lead to the induction of DSBs which are associated specifically with S-phase cells consistent with the idea that they are formed at stalled replication forks in which HR plays a major role in repair. That DNA-PKcs is in some way involved in the repair of the precursors to replication-induced DSB remains an open question. Persistent non-DSB oxidative damage also leads to an increase in RAD51 positive DSBs. Both simple and complex non-DSB DNA damage may therefore contribute to indirect DSBs induced by ionising radiation at replication forks.

  2. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Ruben A. Abagyan, PhD

    2004-04-15T23:59:59.000Z

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  3. Exemption from Application of the Service Contract Act -Certification UT-B Contracts Div Maintenance, Calibration, or Repair of Certain Equipment

    E-Print Network [OSTI]

    Pennycook, Steve

    Exemption from Application of the Service Contract Act - Certification UT-B Contracts Div-sca-equip-certification-ext-venx-mar09.doc EXEMPTION FROM APPLICATION OF THE SERVICE CONTRACT ACT ­ MAINTENANCE, CALIBRATION, OR REPAIR to the conditions in paragraph (a) of this provision, and the Company determines that the Service Contract Act ­ (1

  4. Exemption from Application of the Service Contract Act -Requirements UT-B Contracts Div Maintenance, Calibration, or Repair of Certain Equipment

    E-Print Network [OSTI]

    Pennycook, Steve

    Exemption from Application of the Service Contract Act - Requirements UT-B Contracts Div-sca-equip-requirement-ext-jan08.doc EXEMPTION FROM APPLICATION OF THE SERVICE CONTRACT ACT ­ MAINTENANCE, CALIBRATION, OR REPAIR inapplicable, and the Agreement shall become subject to the Service Contract Act. In such case, the procedures

  5. SMITH, GLEN. Bond Characteristics and Qualifications of Adhesives for Marine Applications and Steel Pipe Repair. (Under the direction of Dr. Sami Rizkalla.)

    E-Print Network [OSTI]

    designs using new materials. Adhesives that bond metals, plastics, FRP and other materials have been used for marine application and repair of steel pipeline. #12;BOND CHARACTERISTICS AND QUALIFICATIONS OF ADHESIVES of Science Department of Civil, Construction, and Environmental Engineering Raleigh 2005 APPROVED BY

  6. By unravelling some of the mechanisms of lung injury, repair and fibrosis, Professor Bruce D Uhal's collaborative research is opening up the potential development of novel pharmaceutics

    E-Print Network [OSTI]

    Liu, Taosheng

    By unravelling some of the mechanisms of lung injury, repair and fibrosis, Professor Bruce D Uhal the biological molecules important to the function of the lungs. I was attracted to physiology because the many in your laboratory? Research in my laboratory has shown that during lung injury, Type II cells begin

  7. Repair of O sup 6 -ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea

    SciTech Connect (OSTI)

    Thomale, J.; Huh, Namho; Nehls, P.; Eberle, G.; Rajewsky, M.F. (Univ. of Essen Medical School (West Germany))

    1990-12-01T23:59:59.000Z

    O{sup 6}-Ethylguanine (O{sup 6}-EtGua) is one of about a dozen different alkylation products formed in the DNA of cells exposed to the alkylating N-nitroso carcinogen N-ethyl-N-nitrosourea (EtNU). The authors have evaluated selectively the relative capacity of cells for the specific enzymatic repair of O{sup 6}-EtGua as a determinant for the probability of malignant conversion. Eleven O{sup 6}-EtGua-repair-proficient (R{sup +}) variant subclones were isolated from the O{sup 6}-EtGua-repair-deficient (R{sup {minus}}) clonal rat fibroblast line 208F by selection for resistance to 1,3-bis-(2-chloroethyl)-1-nitrosourea. Contrary to the 208F wild-type cells, all variants expressed O{sup 6}-methylguanine-DNA methyltransferase activity, while both kinds of cells were deficient for repair of the DNA ethylation products O{sup 2}- and O{sup 4}-ethylthymine. After exposure to EtNU cells were analyzed for the formation of piled-up foci in monolayer culture and of anchorage-independent colonies in semisolid agar medium. No significant differences in the frequencies of piled-up foci were found between wild-type and variant cells after exposure to the major reactive metabolite of benzo(a)pyrene, (+)-7{beta},8{alpha}-dihydroxy-9,10{alpha}-epoxy7,8,9,10{alpha}-tetrahydrobenzo(a)pyrene, for which stable binding to guanine O{sup 6} in cellular DNA has not been observed. The relative capacity of cells for repair of O{sup 6}-alkylguanine is, therefore, a critical determinant for their risk of malignant conversion by N-nitroso carcinogens.

  8. Alternative Farm Business Models

    E-Print Network [OSTI]

    Klinefelter, Danny A.

    2009-03-26T23:59:59.000Z

    ? Bulk feed, fuel, fertilizer and grain storage ? Processing plants ? Feed mills ? Repair shops ? Trucking ? A leasing company ? Biodiesel processing to produce their own fuel ? Self insurance pools ? Genetic services (i.e., sires and donors...

  9. Missouri School District Charges Up

    Broader source: Energy.gov [DOE]

    Missouri's Lee's Summit R-7 school district's distribution fleet was tired. Many of the vehicles had racked up more than 300,000 miles and made frequent trips to the shop to repair the 20 plus-year-old parts.

  10. Building Green in Greensburg: Dillons Kwik Shop

    Office of Energy Efficiency and Renewable Energy (EERE)

    This poster highlights energy efficiency, renewable energy, and sustainable features of the high-performing Dillons Kwik Stop building in Greensburg, Kansas.

  11. Improving shop floor visualization and metrics

    E-Print Network [OSTI]

    Lawler, Maureen E. (Maureen Elizabeth)

    2010-01-01T23:59:59.000Z

    Within the Technical Operations division of Novartis Pharmaceuticals, there is an aggressive vision to be the "Toyota" of the Pharma Industry by 2010. To accomplish this, PharmOps Switzerland has embraced operational ...

  12. , HYBRID HEURISTICS FOR THE PERMUTATION FLOW SHOP ...

    E-Print Network [OSTI]

    2006-11-05T23:59:59.000Z

    Nov 5, 2006 ... 2: Schedule the first two jobs minimizing the partial schedule. ..... set parameters and load balance the various components of the algorithm.

  13. Lesson 56: Shopping, Buying and Selling

    E-Print Network [OSTI]

    [Dinar] Aljeria / Libya / Tunisia [Algeria / Libya / Tunisia] Ougiya [Oguiya] Mauritania [Mauritania

  14. A Romeo Club in a Donut Shop

    E-Print Network [OSTI]

    Murphy, Scott Patrick

    2009-01-01T23:59:59.000Z

    would work mostly in a smelter doing sledgehammer work, butsurreptitiously taken from the smelter. I had done a goodfrom working in the hot smelters to working outside on

  15. The Innovation Shop Where students conceive, design,

    E-Print Network [OSTI]

    Mountziaris, T. J.

    , forces, energy and people ­ the world of mechanical and industrial engineers. Today's engineering generation of engineers College of Engineering Mechanical and Industrial Engineering Department "Engineers mechanical and industrial engineering projects ­ including all their design, modeling, manufacturing

  16. Weatherization Assistance Available at Florida Pie Shop

    Office of Energy Efficiency and Renewable Energy (EERE)

    Pie in the Sky, a seemingly simple store that offers customers fresh-baked desserts, is providing a second treat: weatherization.

  17. FormCampusMachineShopsLabs.doc

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA)Budget(DANCE) Target 1Annual Electricity Delivery

  18. Repair of 254 nm ultraviolet-induced (6-4) photoproducts: monoclonal antibody recognition and differential defects in xeroderma pigmentosum complementation groups A, D, and variant

    SciTech Connect (OSTI)

    Hiramoto, T.; Matsunaga, T.; Ichihashi, M.; Nikaido, O.; Fujiwara, Y.; Mishima, Y. (Kobe Univ. (Japan))

    1989-11-01T23:59:59.000Z

    Repair kinetics of ultraviolet (UV) light-induced (6-4) photoproducts in xeroderma pigmentosum complementation group A, D, and variant cells were studied by the enzyme-linked immunosorbent assay (ELISA) using a specific monoclonal antibody raised against (6-4) photoproducts, together with unscheduled DNA synthesis (UDS) and loss of T4 endonuclease V-susceptible sites (ESS). Group AXP35KO cells completely failed to repair both ESS (cyclobutane pyrimidine dimers) and antibody-recognizing (6-4) photoproducts until tested 24 h after irradiation, and had 2% early-time UDS. Group DXP43KO cells showed about 10% removal of both (6-4) photoproducts and ESS in 24 h, despite showing a residually higher level of 40% early-time and cumulative UDS. Thus, the results substantiated the extreme UV hypersensitivity of XP group A and D cells. However, XP52KO variant cells exhibited the normal level of UDS and ESS loss, but a slightly reduced repair of antibody-recognizing (6-4) photoproducts at 6 and 12 h after irradiation, which may account for a small UV hypersensitivity of the XP variant cells.

  19. Mutagenic processing and strand-specific repair of solar light-induced dipyrimidine photoproducts in rodent cells

    SciTech Connect (OSTI)

    Drobetsky, E.A. [Hopital Maisonneuve-Rosemont, Montreal (Canada); Sage, E. [Institut Curie, Paris (France)

    1994-12-31T23:59:59.000Z

    Although mutations induced by {open_quotes}UVC-like{close_quotes} dipyrimidine photoproducts during sunlight exposure have been directly implicated in multistage photocarcinogenesis, the utility of 254nm UV as a paradigm for broad spectrum solar mutagenesis is questionable. To address this issue, the spectrum of mutations induced by simulated sunlight (SSL) at the adrenine phosphoribosyltransferase locus of Chinese hamster ovary cells has been characterized, and aligned with that previously established for 254nm UV in the same gene. Virtually all SSL-induced events were recovered at potential dinucleotide target sites, most of which could also be implicated in UVC mutagenesis, confirming a preeminent role for cyclobutane dimers and/or (6-4) photoproducts in sunlight-exposed rodent cells. However, striking differences were also noted in the frequency and distribution of mutational classes generated by SSL vs. UVc. Whereas C->T transitions were clearly the most frequent UVC-induced event (58%), three types of base substitution contributed substantially to the SSL spectrum; C->T transitions (35%), T->G transversions (25%), and tandem double CC->TT events (25%). In addition, a significantly greater fraction of SSL-induced mutations (94%) could be attributed to dipyrimidine photoproducts on the non-transcribed strand of the aprt gene than was observed following treatment with 254nm UV (63%). Taken together, the data indicate remarkable differences between UVC- and sunlight-exposed rodent cells in the distribution, strand-specific repair, and/or metabolic processing of similar premutagenic (dipyrimidine) photoproducts.

  20. Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutS[beta

    SciTech Connect (OSTI)

    Tseng, Quincy; Orans, Jillian; Hast, Michael A.; Iyer, Ravi R.; Changela, Anita; Modrich, Paul L.; Beese, Lorena S. (Duke)

    2012-03-16T23:59:59.000Z

    MutS{beta} is a eukaryotic mismatch repair protein that preferentially targets extrahelical unpaired nucleotides and shares partial functional redundancy with MutS{alpha} (MSH2-MSH6). Although mismatch recognition by MutS{alpha} has been shown to involve a conserved Phe-X-Glu motif, little is known about the lesion-binding mechanism of MutS{beta}. Combined MSH3/MSH6 deficiency triggers a strong predisposition to cancer in mice and defects in msh2 and msh6 account for roughly half of hereditary nonpolyposis colorectal cancer mutations. These three MutS homologs are also believed to play a role in trinucleotide repeat instability, which is a hallmark of many neurodegenerative disorders. The baculovirus overexpression and purification of recombinant human MutS{beta} and three truncation mutants are presented here. Binding assays with heteroduplex DNA were carried out for biochemical characterization. Crystallization and preliminary X-ray diffraction analysis of the protein bound to a heteroduplex DNA substrate are also reported.

  1. A novel role for Gadd45? in base excision repair: Modulation of APE1 activity by the direct interaction of Gadd45? with PCNA

    SciTech Connect (OSTI)

    Kim, Hye Lim [Department of Life Science, Dongguk University, 30 Pildong-ro 1-gil, Jung-gu, Seoul 100-715 (Korea, Republic of) [Department of Life Science, Dongguk University, 30 Pildong-ro 1-gil, Jung-gu, Seoul 100-715 (Korea, Republic of); Institute of Environmental Medicine for Green Chemistry, Dongguk University, 30 Pildong-ro 1-gil, Jung-gu, Seoul 100-715 (Korea, Republic of); Department of Pharmacology, Institute for Biomedical Science (IBMS), School of Medicine, Kyung Hee University, Seoul 130-701 (Korea, Republic of); Kim, Sang Uk [School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of) [School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of); Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of); Seo, Young Rok, E-mail: seoyr1@naver.com [Department of Life Science, Dongguk University, 30 Pildong-ro 1-gil, Jung-gu, Seoul 100-715 (Korea, Republic of); Institute of Environmental Medicine for Green Chemistry, Dongguk University, 30 Pildong-ro 1-gil, Jung-gu, Seoul 100-715 (Korea, Republic of); Department of Pharmacology, Institute for Biomedical Science (IBMS), School of Medicine, Kyung Hee University, Seoul 130-701 (Korea, Republic of)

    2013-05-03T23:59:59.000Z

    Highlights: ? Emerging critical role for Gadd45? in modulating BER activity. ? Identifying specific PCNA binding site on Gadd45? protein. ? Regulating APE1 activity through interaction between Gadd45? and PCNA. ? Suggesting potential role of Gadd45?–PCNA binding in pancreatic carcinogenesis. -- Abstract: The growth arrest and DNA damage inducible, alpha (Gadd45?) protein regulates DNA repair by interacting with proliferating cell nuclear antigen (PCNA). Our previous study suggested a potential role for Gadd45? in the base excision repair (BER) pathway by affecting apurinic/apyrimidinic endonuclease 1 (APE1) protein in addition to its accepted role in nucleotide excision repair (NER). Here, we investigated whether the interaction of Gadd45? with PCNA affects APE1 activity. To address this issue, we used a siRNA directed to Gadd45? and a form of Gadd45? with a mutation to the predicted site of PCNA binding. There was a reduction of APE1 activity in cells transfected with the Gadd45? siRNA. Furthermore, the interaction of Gadd45? with PCNA and APE1 was lower in cells transfected with mutant Gadd45? compared with cells transfected with wild-type Gadd45?. Indeed, we observed that the APE1 activity in the Gadd45?-interacting complex was significantly lower in cells that overexpress mutant Gadd45? compared with cells that overexpress wild-type Gadd45?. We conclude that the PCNA binding site on Gadd45? plays a critical role in modulating the interaction with PCNA and APE1, affecting BER activity. These results provide novel insights into the mechanisms by which BER activity is modulated, although the interaction of Gadd45? with APE1 needs to be clarified.

  2. Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.

    SciTech Connect (OSTI)

    Tsutakawa, Susan E.; Shin, David S.; Mol, Clifford D.; Izum, Tadahide; Arvai, Andrew S.; Mantha, Anil K.; Szczesny, Bartosz; Ivanov, Ivaylo N.; Hosfield, David J.; Maiti, Buddhadev; Pique, Mike E.; Frankel, Kenneth A.; Hitomi, Kenichi; Cunningham, Richard P.; Mitra, Sankar; Tainer, John A.

    2013-03-22T23:59:59.000Z

    Non-coding apurinic/apyrimidinic (AP) sites in DNA form spontaneously and as DNA base excision repair intermediates are the most common toxic and mutagenic in vivo DNA lesion. For repair, AP sites must be processed by 5' AP endonucleases in initial stages of base repair. Human APE1 and bacterial Nfo represent the two conserved 5' AP endonuclease families in the biosphere; they both recognize AP sites and incise the phosphodiester backbone 5' to the lesion, yet they lack similar structures and metal ion requirements. Here, we determined and analyzed crystal structures of a 2.4 ? resolution APE1-DNA product complex with Mg(2+) and a 0.92 Nfo with three metal ions. Structural and biochemical comparisons of these two evolutionarily distinct enzymes characterize key APE1 catalytic residues that are potentially functionally similar to Nfo active site components, as further tested and supported by computational analyses. We observe a magnesium-water cluster in the APE1 active site, with only Glu-96 forming the direct protein coordination to the Mg(2+). Despite differences in structure and metal requirements of APE1 and Nfo, comparison of their active site structures surprisingly reveals strong geometric conservation of the catalytic reaction, with APE1 catalytic side chains positioned analogously to Nfo metal positions, suggesting surprising functional equivalence between Nfo metal ions and APE1 residues. The finding that APE1 residues are positioned to substitute for Nfo metal ions is supported by the impact of mutations on activity. Collectively, the results illuminate the activities of residues, metal ions, and active site features for abasic site endonucleases.

  3. Remote repair appliance

    DOE Patents [OSTI]

    Heumann, F.K.; Wilkinson, J.C.; Wooding, D.R.

    1997-12-16T23:59:59.000Z

    A remote appliance for supporting a tool for performing work at a work site on a substantially circular bore of a work piece and for providing video signals of the work site to a remote monitor comprises: a base plate having an inner face and an outer face; a plurality of rollers, wherein each roller is rotatably and adjustably attached to the inner face of the base plate and positioned to roll against the bore of the work piece when the base plate is positioned against the mouth of the bore such that the appliance may be rotated about the bore in a plane substantially parallel to the base plate; a tool holding means for supporting the tool, the tool holding means being adjustably attached to the outer face of the base plate such that the working end of the tool is positioned on the inner face side of the base plate; a camera for providing video signals of the work site to the remote monitor; and a camera holding means for supporting the camera on the inner face side of the base plate, the camera holding means being adjustably attached to the outer face of the base plate. In a preferred embodiment, roller guards are provided to protect the rollers from debris and a bore guard is provided to protect the bore from wear by the rollers and damage from debris. 5 figs.

  4. Remote repair appliance

    DOE Patents [OSTI]

    Heumann, Frederick K. (Ballston Spa, NY); Wilkinson, Jay C. (Ballston Spa, NY); Wooding, David R. (Saratoga Springs, NY)

    1997-01-01T23:59:59.000Z

    A remote appliance for supporting a tool for performing work at a worksite on a substantially circular bore of a workpiece and for providing video signals of the worksite to a remote monitor comprising: a baseplate having an inner face and an outer face; a plurality of rollers, wherein each roller is rotatably and adjustably attached to the inner face of the baseplate and positioned to roll against the bore of the workpiece when the baseplate is positioned against the mouth of the bore such that the appliance may be rotated about the bore in a plane substantially parallel to the baseplate; a tool holding means for supporting the tool, the tool holding means being adjustably attached to the outer face of the baseplate such that the working end of the tool is positioned on the inner face side of the baseplate; a camera for providing video signals of the worksite to the remote monitor; and a camera holding means for supporting the camera on the inner face side of the baseplate, the camera holding means being adjustably attached to the outer face of the baseplate. In a preferred embodiment, roller guards are provided to protect the rollers from debris and a bore guard is provided to protect the bore from wear by the rollers and damage from debris.

  5. Overview: Recycling and Repair

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    supports the deployment of advanced lightweighting materials Increased use of recycledrenewable materials is one of the three technology specific Materials goals for 2010...

  6. Service and Repair Work

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomelandMultivariate Metal-Organic Frameworks |

  7. Motor Repair Tech Brief

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,OfficialProductsUptake and Release:Characteristics | Department

  8. 'Escherichia Coli' MutS Tetramerization Domain Structure Reveals That Stable Dimers But Not Tetramers are Essential for DNA Mismatch Repair in Vivo

    SciTech Connect (OSTI)

    Mendillo, M.L.; Putnam, C.D.; Kolodner, R.D.; /UC, San Diego

    2007-07-10T23:59:59.000Z

    The E. coli mispair binding protein MutS forms dimers and tetramers in vitro, although the functional form in vivo is under debate. Here we demonstrate that the MutS tetramer is extended in solution using small angle x-ray scattering (SAXS) and the crystal structure of the C-terminal 34 amino acids of MutS containing the tetramer-forming domain fused to maltose binding protein (MBP). Wild-type C-terminal MBP fusions formed tetramers and could bind MutS and MutS-MutL-DNA complexes. In contrast, Asp835Arg and Arg840Glu mutations predicted to disrupt tetrameric interactions only allowed dimerization of MBP. A chromosomal MutS truncation mutation eliminating the dimerization/tetramerization domain eliminated mismatch repair, whereas the tetramer-disrupting MutS Asp835Arg and Arg840Glu mutations only modestly affected MutS function. These results demonstrate that dimerization but not tetramerization of the MutS C- terminus is essential for mismatch repair.

  9. Spending Plan Worksheet Instructions: 1.Calculate monthly net income in box 1

    E-Print Network [OSTI]

    , insurance premiums, auto servicing, tires, license, birthdays and holidays, educational costs, vacations/Taxes* $_______ Utilities Telephone $_______ Heating $_______ Electricity` $_______ Trash/garbage $_______ Water and repairs $_______ Other transportation $_______ $_______ Personal/MedicalCare $_______ Education

  10. C:\\Documents and Settings\\vtabb\\My Documents\\Downloads\\Hazard Analysis Manual.doc 5/22/2012 1 of 84 UAF Facilities Services

    E-Print Network [OSTI]

    Hartman, Chris

    area Lockout/tagout, proper grounding of frame, manufacturers instructions strictly followed PPE Activation during repair Noise Auto start and/or human error Equipment Operation Lockout/Tagout Use Hearing

  11. Job Hazard Analysis Manual Updated 10/6/04

    E-Print Network [OSTI]

    Escher, Christine

    and fire hazards from area Electrical Shock Improper grounding, improper operations and maintenance Lockout Activation during repair Auto start and/or human error Lockout/Tagout Noise Equipment Operation Use Hearing

  12. FREQUENTLY USED ACCOUNT CODES August 14, 2013 (1) Use this Code for Personal Service Contracts

    E-Print Network [OSTI]

    Caughman, John

    Minor Equipment (Non-Capitalized) 20250 Parts-Auto & Equip Replacement 20251 Vehicle Tires 20252 Radiological Waste Dispo *23370 Recycling Expense i.e. Iron Mountain 235XX MAINTENANCE & REPAIRS *23501 Equip

  13. Mobile and Ubiquitous Computing Auto-identification

    E-Print Network [OSTI]

    Roussos, George

    and legal implications and challenges Supply-chain applications · Track products ­ SKU level ­ Item level;2 More about supply-chains · Introduced by US Army after first Gulf War · Wall-Mart has set deadline ­ Possibly under 1 cent in the next 2-3 years · Wireless communications ­ Widely available bandwidth ­ High

  14. Compressive auto-indexing in femtosecond nanocrystallography

    E-Print Network [OSTI]

    Maia, F R N C; Marchesini, S; 10.1016/j.ultramic.2010.10.016

    2010-01-01T23:59:59.000Z

    Ultrafast nanocrystallography has the potential to revolutionize biology by enabling structural elucidation of proteins for which it is possible to grow crystals with 10 or fewer unit cells on the side. The success of nanocrystallography depends on robust orientation-determination procedures that allow us to average diffraction data from multiple nanocrystals to produce a three dimensional (3D) diffraction data volume with a high signal-to-noise ratio. Such a 3D diffraction volume can then be phased using standard crystallographic techniques. "Indexing" algorithms used in crystallography enable orientation determination of diffraction data from a single crystal when a relatively large number of reflections are recorded. Here we show that it is possible to obtain the exact lattice geometry from a smaller number of measurements than standard approaches using a basis pursuit solver.

  15. Auto-steering apparatus and method

    DOE Patents [OSTI]

    McKay, Mark D.; Anderson, Matthew O.

    2007-03-13T23:59:59.000Z

    A vehicular guidance method involves providing a user interface using which data can be input to establish a contour for a vehicle to follow, the user interface further configured to receive information from a differential global positioning system (DGPS), determining cross track and offset data using information received from the DGPS, generating control values, using at least vehicular kinematics, the cross track, and the offset data, and providing an output to control steering of the vehicle, using the control values, in a direction to follow the established contour while attempting to minimize the cross track and the offset data.

  16. Overview: STEEL Auto/Steel Partnership

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    projects that meet the vision. *Communicates the technical results and benefits to the automotive industry. w w w . a - s p . o r g 2008 DOE Merit Review THE PARTNERSHIP...

  17. Less platinum means lower prices for autos

    Broader source: Energy.gov [DOE]

    How technology developed by researchers at 3M is reducing the amount of platinum necessary for a fuel cell system, helping to make the technology more practical for consumer vehicles.

  18. Detroit Auto Show 2012 | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33Frequently20,000 Russian NuclearandJunetrack graphics4 VolumeAguaDepartmentEnergy Left: Gary10

  19. 2015 Washington Auto Show | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed off Energy.gov. Are you sure you want toworldPower 2010 1 TNewsEnergyDepartmentof15

  20. 2013 Washington Auto Show | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed off Energy.gov. Are you0 ARRA Newsletters 2010 ARRA Newsletters American20122 Wind2013 Annual20133

  1. From Autos to Accelerators | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China 2015of 2005 at Iowa WindFiscal.pdf09 budget, includingDepartmentInFebruary

  2. Damage-prone regions in structural composite materials are difficult to detect and even harder to repair. Damage is preceded by complex spatial and temporal changes in stress state, and it is

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    Materials Seminar Damage-prone regions in structural composite materials are difficult to detect and even harder to repair. Damage is preceded by complex spatial and temporal changes in stress state about in response to damage or high-stress conditions include: (1) signal generation to warn of ensuing

  3. CT Imaging Findings and Their Relevance to the Clinical Outcomes After Stent Graft Repair of Penetrating Aortic Ulcers: Six-year, Single-center Experience

    SciTech Connect (OSTI)

    Shin, Ji Hoon [University of Ulsan College of Medicine, Asan Medical Center, Department of Radiology and Research Institute of Radiology (Korea, Republic of); Angle, John F.; Park, Auh Whan; Anderson, Curtis; Sabri, Saher S.; Turba, Ulku C. [University of Virginia Health System, Division of Angiography, Interventional Radiology and Special Procedures, Department of Radiology (United States); Kern, John A.; Cherry, Kenneth J. [University of Virginia Health System, Department of Surgery (United States); Matsumoto, Alan H., E-mail: ahm4d@virginia.edu [University of Virginia Health System, Division of Angiography, Interventional Radiology and Special Procedures, Department of Radiology (United States)

    2012-12-15T23:59:59.000Z

    Purpose: To present the computed tomographic (CT) imaging findings and their relevance to clinical outcomes related to stent graft placement in patients with penetrating aortic ulcers (PAUs). Methods: Medical and imaging records and imaging studies were reviewed for consecutive patients who underwent stent graft repair of a PAU. The distribution and characteristics of the PAU, technical success of stent graft repair, procedure-related complications, associated aortic wall abnormalities, and outcomes of the PAUs at follow-up CT scans were evaluated. Results: Fifteen patients underwent endovascular treatment for PAU. A total of 87% of the PAUs were in the proximal (n = 8) or distal (n = 5) descending thoracic aorta. There was a broad spectrum of PAU depth (mean, 7.9 {+-} 5.6 mm; range 1.5-25.0 mm) and diameter (mean, 13.5 {+-} 9.7 mm; range 2.2-41.0 mm). Atherosclerosis of the thoracic aorta and intramural hematoma were associated in 53 and 93% of the patients, respectively. Technical success was achieved in 100%. Two or more stent grafts were used in five patients. Endoleaks were observed in two patients within 2 weeks of the procedure, both of which resolved spontaneously. At follow-up CT scanning, regression and thrombosis of the PAUs were observed in all patients. The average patient survival was 61.8 months, with an overall mortality of 13% (2 of 15) at follow-up. Neither death was related to the endograft device or the PAU. Conclusion: Endovascular stent graft placement was safe and effective in causing regression and thrombosis of PAUs in this small series of patients. Two or more stent grafts were used in five patients (33%) with associated long-segmental atherosclerotic changes of the thoracic aorta or intramural hematoma.

  4. Copyright 2004 Auto-ID Labs, All Rights Reserved The Auto-ID Labs

    E-Print Network [OSTI]

    Brock, David

    Reserved Several Types of Webs · The Web of Information HTML and the World Wide Web · The Web of Things-ID Labs, All Rights Reserved A Special Word of Thanks to my Colleagues · Stuart J. Allen - Professor Reserved A Special Word of Thanks to my Colleagues (continued) · Nhat-So Lam ­ Family Retail Business

  5. Lead exposure among small-scale battery recyclers, automobile radiator mechanics, and their children in Manila, the Philippines

    SciTech Connect (OSTI)

    Suplido, M.L.; Ong, C.N.

    2000-03-01T23:59:59.000Z

    Blood lead (PbB) and hemoglobin levels (Hb) were determined in 40 battery repair/recycling shop workers, 16 radiator repair shop workers, and 20 children living in the immediate vicinity of these shops. Unexposed residents with similar socio-economic status were also investigated. Mean PbB level was significantly higher for battery workers when compared to radiator workers and unexposed adults. Among battery workers, 94% had PbB levels above the WHO permissible exposure limit of 40 {micro}g/dL for males and 30 {micro}g/dL for females. There was no demarcation between workplace and living quarters; therefore, workers' families were similarly exposed to hazards. Children living in the immediate vicinity of battery shops also had significantly higher mean PbB levels compared to radiator shop children and unexposed children. For workers with PbB > 40 {micro}g/dL, 90% were anemic. Linear regression showed a correlation between Hb level and log{sub 10}PbB. There was no significant relationship between anemia and blood lead in children. The authors conclude that radiator repair activities appeared to increase the body burden of lead, although not up to a level significantly different from unexposed counterparts. Battery recycling/repair activities, however, significantly increased blood lead levels in workers and their children.

  6. Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

    SciTech Connect (OSTI)

    Chen, Xi; Ballin, Jeff D.; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J.; Tomkinson, Alan E.; Wilson, Gerald M.

    2009-05-11T23:59:59.000Z

    The three human LIG genes encode polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination and repair. While numerous studies have identified protein partners of the human DNA ligases (hLigs), there has been little characterization of the catalytic properties of these enzymes. In this study, we developed and optimized a fluorescence-based DNA ligation assay to characterize the activities of purified hLigs. Although hLigI joins DNA nicks, it has no detectable activity on linear duplex DNA substrates with short, cohesive single-strand ends. By contrast, hLigIII{beta} and the hLigIII{alpha}/XRCC1 and hLigIV/XRCC4 complexes are active on both nicked and linear duplex DNA substrates. Surprisingly, hLigIV/XRCC4, which is a key component of the major non-homologous end joining (NHEJ) pathway, is significantly less active than hLigIII on a linear duplex DNA substrate. Notably, hLigIV/XRCC4 molecules only catalyze a single ligation event in the absence or presence of ATP. The failure to catalyze subsequent ligation events reflects a defect in the enzyme-adenylation step of the next ligation reaction and suggests that, unless there is an in vivo mechanism to reactivate DNA ligase IV/XRCC4 following phosphodiester bond formation, the cellular NHEJ capacity will be determined by the number of adenylated DNA ligaseIV/XRCC4 molecules.

  7. A laboratory experiment from the Little Shop of Physics at

    E-Print Network [OSTI]

    Hardy, Darel

    the heating of their palms when the infrared strikes their skin. This is just how certain snakes can "see. Cooler objects emit infrared; we call this "thermal radiation" because it is an impor- tant mechanism, electromagnetic radiation is responsible for all life on earth! Visible light and infrared are both kinds

  8. Redressing architecture : the architecture of a fashion work/shop

    E-Print Network [OSTI]

    Mathew, Lena (Lena Mary), 1975-

    2002-01-01T23:59:59.000Z

    At this moment in the twentieth century the discussions about architecture and fashion have suddenly become "in fashion". To many the topic seems suddenly timely or trendy, but unlike theories comparing the artificial ...

  9. Estudia con estilo www.ShopFoothillsMall.com

    E-Print Network [OSTI]

    Rhoads, James

    esco- lar en Arizona y Sonora, el binomio edu- car-aprender parece tomar una nueva di- námica frente

  10. Standard-E hydrogen monitoring system shop acceptance test procedure

    SciTech Connect (OSTI)

    Schneider, T.C.

    1997-10-02T23:59:59.000Z

    The purpose of this report is to document that the Standard-E Hydrogen Monitoring Systems (SHMS-E), fabricated by Mid-Columbia Engineering (MCE) for installation on the Waste Tank Farms in the Hanford 200 Areas, are constructed as intended by the design. The ATP performance will verify proper system fabrication.

  11. Ability - Not Disability: Grocery Shopping and Food Preparation.

    E-Print Network [OSTI]

    Anonymous,

    1981-01-01T23:59:59.000Z

    . Push the handle over the edge of the counter to make it easy to pick up. Use lightweight mixing bowls, pans and dishes. Peelers. Peelers often have small handles that take too much bending and strain to grasp. \\yhen working with any utensil like... to the side of the sink stays firmly in place while potatoes are washed with one hand. Hands can be scrubbed this way also. Washing Glasses. A small dish mop attached to the sink with suction cups or a magnet helps you wash glasses with one hand. Support...

  12. Flow Shop Scheduling with Peak Power Consumption Constraints

    E-Print Network [OSTI]

    2012-09-23T23:59:59.000Z

    1.00. 1.00. 1.00. NA: for these instances, the ro ot. LP relaxations of the form ulations did not solve in less than. 5s. T able. 8: Average optimality gap for instances.

  13. Working Towards 100% Electronic Transactions on the Shop Floor

    E-Print Network [OSTI]

    Terwilliger, M.

    amounts of money on various automation projects in portfolio management technique. a piecemeal fashion. Many companies have made an 3. Building a strategy that art form out of developing short-sighted ROI's. the company would like to be in five ,nd ten... of strategic alternatives are now a necessity. END OF THE ERA OF PORTFOLIO ANALYSIS Shortly after Jack? Welch became Chairman of Gener al Electric, he made a number of interesting statements about corporate strategy. The single point that impressed us...

  14. A laboratory experiment from the Little Shop of Physics at

    E-Print Network [OSTI]

    Hardy, Darel

    that they are bringing the energy of the sun indoors! Now close the curtains in your classroom and turn out the lights for the sky. Can energy be created or destroyed? Overview Energy is the single most important science concept your students will Understanding conservation of energy is vital as students study the earth's energy

  15. Scheduling optimization of a real flexible job shop including side ...

    E-Print Network [OSTI]

    2013-08-19T23:59:59.000Z

    Aug 19, 2013 ... The multitask cell at GKN Aerospace Sweden is a production cell con- ...... In order to demonstrate the effect of the squeezing procedure we solved ..... [13] J. Gao, M. Gen, L. Sun, Scheduling jobs and maintenances in flexible.

  16. assessment mechanics shop: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    When meat juices were added to bags and stored in the trunks of cars for two hours the number of bacteria increased 10-fold indicating the potential for bacterial growth in the...

  17. Priorities in the design of chemical shops at coke plants

    SciTech Connect (OSTI)

    V.I. Rudyka; Y.E. Zingerman; V.V. Grabko; L.A. Kazak [Giprokoks, the State Institute for the Design of Coke-Industry Enterprises, Kharkov (Ukraine)

    2009-07-15T23:59:59.000Z

    Recent trends in the design of chemical equipment at coke plants are described, through the lens of experience at Giprokoks. The main priorities were to improve the removal of impurities from coke oven gas; to improve equipment design on the basis of new materials; to reduce reagent consumption; to reduce the materials and energy consumed in the construction of new equipment; and to minimize impacts on the environment and worker health. Some technological equipment is briefly characterized.

  18. Working Towards 100% Electronic Transactions on the Shop Floor 

    E-Print Network [OSTI]

    Terwilliger, M.

    1985-01-01T23:59:59.000Z

    Drastic changes are taking place in the manufacturing environment—both in continuous process manufacturing and discrete parts manufacturing. Data communications and computer technologies are forging new disciplines and ...

  19. Mallville : mixing uses in the shopping center of the future

    E-Print Network [OSTI]

    Lieberman, Todd O., 1978-

    2004-01-01T23:59:59.000Z

    (cont.) product allows municipalities an alternative strategy for large scale development than simply consenting to the construction of Wal-Marts and power centers. The alignment of private and public interests in the ...

  20. Instruction Guide Shopping Using the Product Keyword Search

    E-Print Network [OSTI]

    Pilyugin, Sergei S.

    and add them to your cart. The Product Search is a very powerful search engine. Start with by entering in the flyout menu. 3. To start searching for an item, enter the item in the search field. Include specific search terms, such as "latex-free gloves" instead of just "gloves". The system is flexible with search

  1. Lean Enterprise Transformation in a Job Shop Environment

    E-Print Network [OSTI]

    McCarthy, Brian P.

    2006-12-15T23:59:59.000Z

    Provider project deliverables for the assessment phase were the following documents: (a) Business System Assessment, (b) Network/Hardware Assessment, and (c) Lean Enterprise Assessment. The Partner personnel provided the primary project manager... Plan Findings and Recommendations. 9 (3) The LET Project SOW assumptions and triple constraints that could potentially impact the overall project (a) scope, (b) time schedule, and (c) overall costs have been summarized. (4) The LET Leadership...

  2. A laboratory experiment from the Little Shop of Physics at

    E-Print Network [OSTI]

    Hardy, Darel

    , pronounced "a-dE-&-'ba-tik" means that there is no transfer of heat between an air parcel and its pump with pressure gauge · Sucker sticks to release air pressure. The most important element in the atmosphere, form when four conditions are present: water vapor, cooled air, supersatura- tion

  3. 1. Williams Shop 15 Spring St., 413-458-3605

    E-Print Network [OSTI]

    Aalberts, Daniel P.

    Spring St., 413-458-8321 8. Nature's Closet 61 Spring St., 413-458-7909 9. Sweets and Beans Confieserie & Vines Beer Garden & Brasserie 16 Water St., 413-884-1372 31. Amy's Cottage 24 Water St., 413-458-4305 32. Water Street Books 26 Water St., 413-458-8072 33. In Touch Massage & Day Spa 84 Water St., 413

  4. Synchronous manufacturing : implementing "pull" production in a job shop environment

    E-Print Network [OSTI]

    Schoch-Rodriguez, Malia (Malia Jean)

    2006-01-01T23:59:59.000Z

    In a recent contract, CVN 78, Northrop Grumman Corporation has been experiencing significant pressure from the Navy to reduce cost in the design and construction of the new nuclear aircraft carrier class. Furthermore, the ...

  5. CRAD, Machine Shop Safe Operations Assessment Plan | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S. Department ofJune 2,The BigSidingState6Report,COMMENTSpurpose of this

  6. Energy Savers: Your One Stop Shop for Energy Efficiency Upgrades |

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011AT&T,OfficeEnd of Year 2010 SNFEnergy Policy ActEnergy |Division, OAPM |Energyowners

  7. Post-Holiday Holiday Shopping | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China 2015of 2005UNS Electric, Inc.Department ofAmountAtomic7951Fossil fuel fired

  8. January 2014 Cybersecurity Awareness Campaign - Secure Online Shopping |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment ofLetter Report: I11IG002RTC3 | 12/1/2014January(HSS)Department

  9. Green your Back to School Shopping List! | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy ChinaofSchaefer To: CongestionDevelopment of aLoggingsubscriber to the GreenOneSave energy

  10. Klamath County Shops Space Heating Low Temperature Geothermal Facility |

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant Jump to: navigation, search GEOTHERMAL ENERGYGeothermal Home Kizildere IOpenOpen

  11. ProteinShop: A Tool for Interactive Protein

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItem Not Found Item Not Foundenhancer activity than

  12. Holiday Shopping and Electric Vehicles | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh School football High SchoolBundlesHistory

  13. Property:Building/FloorAreaGroceryShops | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal PwerPerkins County, Nebraska:Precourt Institute forToolkit JumpBuilding/Category"

  14. Savannah River Site - Central Shops GW OU | Department of Energy

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33Frequently AskedEnergy SmallImplementing J-F-1 SECTION JtheNEWMR.Y : JJaneCMP Pits

  15. DNA demethylation by DNA repair

    E-Print Network [OSTI]

    Gehring, Mary

    Active DNA demethylation underlies key facets of reproduction in flowering plants and mammals and serves a general genome housekeeping function in plants. A family of 5-methylcytosine DNA glycosylases catalyzes plant ...

  16. From ShopTalk to ShopMobile: Vision-Based Barcode Scanning with Mobile Phones for

    E-Print Network [OSTI]

    Kulyukin, Vladimir

    ]. These difficulKes cause VI shoppers to abandon searching for desirable products or seNle are unfamiliar with the store layout, others become irritated with long searches, and s

  17. Working Title Scientist 3 Auto req ID 1024BR

    E-Print Network [OSTI]

    Mazzotti, Frank

    of these vegetation management efforts. Will work with the staff and management at the field stations. Reports to the Vegetation Management Section's Invasive Species Unit Lead Scientist and will work closely. Prepares required work orders and reports for planning, implementing and documenting vegetation management

  18. auto thermal reforming: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a dozen states are now considering whether to deregulate prices and entry for retail electric power service; the most aggressive states are pursuing policies to allow retail...

  19. Collective Mind: towards practical and collaborative auto-tuning

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    exploration times, and lack of unified mechanisms for preserving and sharing of optimization knowledge Mind knowledge management system. In contrast with previous cTuning framework, this modular, collaborative knowledge management, public repository of knowledge, NoSQL repository, code and data sharing

  20. Auto shredder residue recycling: Mechanical separation and pyrolysis

    SciTech Connect (OSTI)

    Santini, Alessandro [Department of Industrial Chemistry and Materials, University of Bologna, Viale Risorgimento 4, I-40136 Bologna (Italy); Passarini, Fabrizio, E-mail: fabrizio.passarini@unibo.it [Department of Industrial Chemistry and Materials, University of Bologna, Viale Risorgimento 4, I-40136 Bologna (Italy); Vassura, Ivano [Department of Industrial Chemistry and Materials, University of Bologna, Viale Risorgimento 4, I-40136 Bologna (Italy); Serrano, David; Dufour, Javier [Department of Chemical and Energy Technology, ESCET, Universidad Rey Juan Carlos, c/Tulipan s/n, 28933 Mostoles, Madrid (Spain); Instituto IMDEA Energy, c/Tulipan s/n, 28933 Mostoles, Madrid (Spain); Morselli, Luciano [Department of Industrial Chemistry and Materials, University of Bologna, Viale Risorgimento 4, I-40136 Bologna (Italy)

    2012-05-15T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer In this work, we exploited mechanical separation and pyrolysis to recycle ASR. Black-Right-Pointing-Pointer Pyrolysis of the floating organic fraction is promising in reaching ELV Directive targets. Black-Right-Pointing-Pointer Zeolite catalyst improve pyrolysis oil and gas yield. - Abstract: sets a goal of 85% material recycling from end-of-life vehicles (ELVs) by the end of 2015. The current ELV recycling rate is around 80%, while the remaining waste is called automotive shredder residue (ASR), or car fluff. In Europe, this is mainly landfilled because it is extremely heterogeneous and often polluted with car fluids. Despite technical difficulties, in the coming years it will be necessary to recover materials from car fluff in order to meet the ELV Directive requirement. This study deals with ASR pretreatment and pyrolysis, and aims to determine whether the ELV material recycling target may be achieved by car fluff mechanical separation followed by pyrolysis with a bench scale reactor. Results show that flotation followed by pyrolysis of the light, organic fraction may be a suitable ASR recycling technique if the oil can be further refined and used as a chemical. Moreover, metals are liberated during thermal cracking and can be easily separated from the pyrolysis char, amounting to roughly 5% in mass. Lastly, pyrolysis can be a good starting point from a 'waste-to-chemicals' perspective, but further research should be done with a focus on oil and gas refining, in order both to make products suitable for the chemical industry and to render the whole recycling process economically feasible.

  1. Self, Esteemed: Contemporary Auto/biographical Theatre in Latin America

    E-Print Network [OSTI]

    Ward, Julie Ann

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    E-Print Network [OSTI]

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    E-Print Network [OSTI]

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    )) The degree of the polynomial P (s) DSP Digital Signal Processor card(X) The cardinality of the set X kp The proportional gain value of a PID controller ki The integral gain value of a PID controller kd The derivative gain value of a PID controller Kp... The interval of kp values Ki The interval of ki values Kd The interval of kd values ?x? The L2 vector norm of x ?A? The matrix norm of A ?F,G? The inner product of F and G OLHP The open left half plane ORHP The open right half plane LTI Linear Time Invariant vi...

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    E-Print Network [OSTI]

    Williams, Samuel

    2008-01-01T23:59:59.000Z

    Victoria Falls, and the Sony-Toshiba-IBM (STI) Cell. Ratherthe dual-socket×eight-core Sony-Toshiba-IBM (STI) Cell QS20DRAM latency. 2.4. STI Cell The Sony Toshiba IBM (STI) Cell

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    cermets: microstructure and objectives Combustion synthesis, also called self-propagating high- temperature synthesis (SHS), is a method ). The introduction of TiCx...

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    E-Print Network [OSTI]

    Flores, Patricia Laura

    1992-01-01T23:59:59.000Z

    . Mean poductivity rate with respect to interface. 23 mean = 7. 49 std. dev. 2 02 7. 0 6. 0 5. 0 4. 0 3. 0 2. 0 mean = 4. 50 std, dev. = 1. 28 mean = 5. 54 std. dev. ? 1. 23 1. 0 0. 0 Drawing ensioning DisplaYing Figure 9. Mean...

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    Boyer, Edmond

    répliques en sismo- logie). Il s'agit donc d'un processus purement temporel. Puri et al. (1986) étudie le

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    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA group currentBradley Nickell Director ofDepartment of Energy

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    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S.ContaminationJulySavannah RiverSustainabilityEnergyDownload

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    Broader source: Energy.gov (indexed) [DOE]

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    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport inEnergy0.pdf Flash2010-60.pdf2 DOE HydrogenPlans | Department

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    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreakingMay 2015ParentsMiddle SchoolPhysics |Travels to MemphisDepartment of