Sample records for association rfa promotes

  1. assessment rfa oak ridge: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    assessment rfa oak ridge First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Oak Ridge Reservation Annual...

  2. RCRA Facilities Assessment (RFA)---Oak Ridge National Laboratory

    SciTech Connect (OSTI)

    Not Available

    1987-03-01T23:59:59.000Z

    US Department of Energy (DOE) facilities are required to be in full compliance with all federal and state regulations. In response to this requirement, the Oak Ridge National Laboratory (ORNL) has established a Remedial Action Program (RAP) to provide comprehensive management of areas where past and current research, development, and waste management activities have resulted in residual contamination of facilities or the environment. This report presents the RCRA Facility Assessment (RFA) required to meet the requirements of RCRA Section 3004(u). Included in the RFA are (1) a listing of all sites identified at ORNL that could be considered sources of releases or potential releases; (2) background information on each of these sites, including location, type, size, period of operation, current operational status, and information on observed or potential releases (as required in Section II.A.1 of the RCRA permit); (3) analytical results obtained from preliminary surveys conducted to verify the presence or absence of releases from some of the sites; and (4) ORNL`s assessment of the need for further remedial attention.

  3. RCRA Facilities Assessment (RFA)---Oak Ridge National Laboratory

    SciTech Connect (OSTI)

    Not Available

    1987-03-01T23:59:59.000Z

    US Department of Energy (DOE) facilities are required to be in full compliance with all federal and state regulations. In response to this requirement, the Oak Ridge National Laboratory (ORNL) has established a Remedial Action Program (RAP) to provide comprehensive management of areas where past and current research, development, and waste management activities have resulted in residual contamination of facilities or the environment. This report presents the RCRA Facility Assessment (RFA) required to meet the requirements of RCRA Section 3004(u). Included in the RFA are (1) a listing of all sites identified at ORNL that could be considered sources of releases or potential releases; (2) background information on each of these sites, including location, type, size, period of operation, current operational status, and information on observed or potential releases (as required in Section II.A.1 of the RCRA permit); (3) analytical results obtained from preliminary surveys conducted to verify the presence or absence of releases from some of the sites; and (4) ORNL's assessment of the need for further remedial attention.

  4. Cancer-associated adipocytes promotes breast tumor radioresistance

    SciTech Connect (OSTI)

    Bochet, Ludivine; Meulle, Aline [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France) [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France); CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, BP 64182, F-31077 Toulouse Cedex (France); Institut National de la Sante et de la Recherche Medicale, INSERM U1048, 1 Avenue du Pr Jean Poulhes, BP 84225, F-31432 Toulouse Cedex (France); Imbert, Sandrine [CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, BP 64182, F-31077 Toulouse Cedex (France)] [CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, BP 64182, F-31077 Toulouse Cedex (France); Salles, Bernard [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France) [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France); CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, BP 64182, F-31077 Toulouse Cedex (France); Valet, Philippe [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France) [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France); Institut National de la Sante et de la Recherche Medicale, INSERM U1048, 1 Avenue du Pr Jean Poulhes, BP 84225, F-31432 Toulouse Cedex (France); Muller, Catherine, E-mail: muller@ipbs.fr [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France) [Universite de Toulouse, UPS, F-31077 Toulouse Cedex (France); CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, BP 64182, F-31077 Toulouse Cedex (France)

    2011-07-22T23:59:59.000Z

    Highlights: {yields} Tumor-surrounding adipocytes contribute to breast cancer progression. {yields} Breast tumor cells previously co-cultivated with mature adipocytes exhibit radioresistance. {yields} Increased in Chk1 phosphorylation is observed in irradiated co-cultivated tumor cells. {yields} IL-6 is over-expressed in tumor cells co-cultivated with adipocytes. {yields} IL-6 exposure confers increased Chk1 phosphorylation and radioresistance in tumor cells. -- Abstract: Mature adipocytes are excellent candidates to influence tumor behavior through heterotypic signaling processes since these cells produce hormones, growth factors, cytokines and other molecules, a heterogeneous group of molecules named adipokines. Using a 2D coculture system, we demonstrate that breast tumor cells previously co-cultivated with mature adipocytes exhibit radioresistance and an earlier and higher increase in the effector kinase Chk1, a phenotype that was associated with decreased cell death as compared to tumor cells grown alone. Interestingly, the adipocytes-induced tumor changes taking place during the coculture time preceding the exposure to IR were sufficient to confer the radioresistant effect. Notorious among the changes brought by adipocytes was the significant increase of IL-6 expression in tumor cells, whose activity may well account for the observed tumor cell protection from IR toxicity. Indeed, our data confirmed the protective role of this cytokine as tumor cells incubated after irradiation with recombinant IL-6 exhibit an increased in Chk1 phosphorylation and a radioresistant phenotype, thus far recapitulating the effects observed in the presence of adipocytes. Our current study sheds light on a new role of tumor-surrounding adipocytes in fostering a radioresistant phenotype in breast tumors, a finding that might have important clinical implications in obese patients that frequently exhibit aggressive diseases.

  5. Grant Title: INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTERS (P30) Funding Opportunity Number: RFA-HD-13-002. CFDA Number(s): 93.865.

    E-Print Network [OSTI]

    Farritor, Shane

    Number: RFA-HD-13-002. CFDA Number(s): 93.865. Agency/Department: Department of Health and Human Services

  6. Grant Title: RESEARCH GRANTS FOR PREVENTING VIOLENCE AND VIOLENCE-RELATED INJURY Funding Opportunity Number: RFA-CE-14-006. CFDA Number(s): 93.136.

    E-Print Network [OSTI]

    Farritor, Shane

    Opportunity Number: RFA-CE-14-006. CFDA Number(s): 93.136. Agency/Department: Centers for Disease Control

  7. A Role for Adjuvant RFA in Managing Hepatic Metastases from Gastrointestinal Stromal Tumors (GIST) After Treatment with Targeted Systemic Therapy Using Kinase Inhibitors

    SciTech Connect (OSTI)

    Hakimé, Antoine, E-mail: thakime@yahoo.com; Cesne, Axel Le, E-mail: Axel.LECESNE@igr.fr; Deschamps, Frederic, E-mail: frederic.deschamps@igr.fr; Farouil, Geoffroy, E-mail: g.farouil@gmail.com; Boudabous, Sana, E-mail: s.boudabous@gmail.com; Aupérin, Anne, E-mail: anne.auperin@igr.fr; Domont, Julien, E-mail: julien.domont@igr.fr; Debaere, Thierry, E-mail: Debaere@igr.fr [Gustave Roussy Institute (France)

    2013-04-16T23:59:59.000Z

    PurposeThis study was designed to assess the role of radiofrequency ablation (RFA) in the multimodality management of gastrointestinal stromal tumors (GIST) in patients undergoing targeted tyrosine kinase inhibitor therapy (TKI) for liver metastases.MethodsOutcomes of 17 patients who underwent liver RFA for 27 metastatic GIST after TKI therapy, from January 2004 to March 2012, were retrospectively analyzed. Mean maximum tumor diameter was 2.5 ± 1 cm (range 0.9–4.5 cm). In seven patients (group A), RFA of all residual tumors was performed, with curative intent, and TKI therapy was discontinued. In five patients (group B), RFA of all residual tumors was performed upon achieving the best morphological response with TKI therapy, which was maintained after RFA. In another five patients (group C), RFA was performed on individual liver metastases which were progressive under TKI therapy.ResultsAll 27 targeted tumors were completely ablated, without local recurrence during the mean follow-up period of 49 months. No major complications occurred. Two minor complications were reported (11 %). Only two patients (both in group C) died at 20 and 48 months. Two-year progression-free survival (PFS) after RFA was 29 % in group A, 75 % in group B, and 20 % in group C.ConclusionsRFA in patients, previously treated with TKI, is feasible and safe. Our data suggest that RFA is a useful therapeutic option in patients with metastatic GIST and should be performed at the time of best clinical response with patient maintained under TKI after the procedure.

  8. Image-Guided Radiofrequency Ablation (RFA) of Unresectable Hepatic Tumors Using a Triple-Spiral-Shaped Electrode Needle: Initial Experience in 34 Patients

    SciTech Connect (OSTI)

    Thanos, Loukas; Poulou, Loukia S., E-mail: ploukia@hotmail.co [General Hospital of Chest Diseases 'Sotiria', Department of Medical Imaging and Interventional Radiology (Greece); Ziakas, Panayiotis D. [Medical School, University of Athens, Department of Hematology (Greece); Kelekis, Alexis D.; Pomoni, Maria; Kelekis, Dimitrios A. [University of Athens, Second Department of Radiology, Medical School, Eugenidion Hospital (Greece)

    2010-02-15T23:59:59.000Z

    We evaluated the safety and efficacy of image-guided radiofrequency ablation (RFA) using a triple-spiral-shaped electrode needle for unresectable primary or metastatic hepatic tumors. Thirty-four patients with 46 index tumors were treated. Ablation zone, morbidity, and complications were assessed. The lesions were completely ablated with an ablative margin of about 1 cm. Five patients (14.7%) with a lesion larger than 4.5 cm had local tumor progression after 1 month and were retreated. Hemothorax, as a major complication, occurred in 1 of 34 patients (3.0%) or 1 of 46 lesions ablated (2.2%). RFA using this new electrode needle can be effective in the treatment of large unresectable hepatic tumors.

  9. Characterization of structural and free energy properties of promoters associated with Primary and Operon TSS

    E-Print Network [OSTI]

    Bansal, Manju

    and Operon TSS in Helicobacter pylori genome and their orthologs ADITYA KUMAR and MANJU BANSAL* Molecular identification of different classes of transcription start sites) of Helicobacter pylori 26695 strain associated with Primary and Operon TSS in Helicobacter pylori genome and their orthologs. J. Biosci. 37 423

  10. Microbially-Promoted Solubilization of Steel Corrosion Products and Fate of Associated Actinides

    SciTech Connect (OSTI)

    Gill Geesey; Timothy Magnuson; Andrew Neal

    2002-06-15T23:59:59.000Z

    Microorganisms have the capacity to modify iron oxides during anaerobic respiration. When the dissimilatory sulfate-reducing bacterium Desulfovibrio desulfuricans G20 respires soluble sulfate during colonization of the solid-phase iron oxide hematite, the sulfide product reacts with the iron to produce the insoluble iron sulfide, pyrrhotite. When soluble uranium is present as uranyl ion, these microorganisms reduce the U(VI) to U(IV) as insoluble uraninite on the hematite surface. There is also evidence that a stable form of U is produced under these conditions that displays an oxidation state between U(VI) and U(iv). The dissimilatory iron reducing bacterium, Shewanella oneidensis MR1 can utilize insoluble hematite as the sole electron acceptor for anaerobic respiration during growth and biofilm development on the mineral. The growth rate, maximum cell density and detachment rate for this bacterium are significantly greater on hematite than on magnetite (111) and (100). The difference could not be attributed to iron site density in the iron oxide. A gene (ferA) encoding a c-tyoe cytochrome involved in dissimulatory iron reduction in the bacterium Geobacter sulfurreducens was completed sequenced and characterized. The sequence information was used to develop an in-situ reverse transcriptase polymerase chain reaction assay that could detect expression of the gene during growth and biofilm development on ferrihydrite at the single cell and microcolony level. X-ray photoelectron spectroscopic analysis revealed that the ferrihydrite was reduced during expression of this gene. The assay was extended to detect expression of genes involved in sulfate reduction and hydrogen reduction in sulfate-reducing bacteria. This assay will be useful to assess mechanisms of biotransformation of minerals including corrosion products on buried metal containers containing radionuclide waste. In summary, the research has shown that dissimilatory sulfate and iron reducing bacteria can modify the iron oxide surfaces that they colonize and promote the reduction and precipitation of actinides such as uranium at these sites

  11. CDK-associated Cullin 1 promotes cell proliferation with activation of ERK1/2 in human lung cancer A549 cells

    SciTech Connect (OSTI)

    Chen, Tian Jun [Respiratory Department, The First Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061 (China)] [Respiratory Department, The First Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061 (China); Gao, Fei [Hua-shan Central Hospital of Xi’an, Xi’an 710043 (China)] [Hua-shan Central Hospital of Xi’an, Xi’an 710043 (China); Yang, Tian; Thakur, Asmitanand; Ren, Hui; Li, Yang; Zhang, Shuo; Wang, Ting [Respiratory Department, The First Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061 (China)] [Respiratory Department, The First Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061 (China); Chen, Ming Wei, E-mail: xjtucmw@163.com [Respiratory Department, The First Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061 (China)

    2013-07-19T23:59:59.000Z

    Highlights: •CDK-associated Cullin 1 (CAC1) expression increases in human lung carcinoma. •CAC1 promotes the proliferation of lung cancer A549 cells. •CAC1 promotes human lung cancer A549 cell proliferation with activation of ERK1/2. -- Abstract: Lung cancer is one of the most common causes of cancer-related death in the world, but the mechanisms remain unknown. In this study, we investigated the expression of CDK-associated Cullin 1 (CAC1) in lung cancer, the effect of CAC1 on the proliferation of human lung cancer A549 cells, and the activation of signaling pathways of mitogen-activated protein kinases (MAPKs). Results showed that CAC1 expression was higher levels in human lung carcinoma than normal lung tissue, and CAC1 siRNA reduced the proliferation of lung cancer A549 cells by decreasing cell activity and cell division in vitro. The proportion of cells treated with CAC1 siRNA increased in the G1 phase and decreased in the S and G2/M phase, indicative of G1 cell cycle arrest. Furthermore, the proportions of early/late apoptosis in lung cancer A549 cells were enhanced with CAC1 siRNA treatment. It was also found that activation of extracellular signal-regulated protein kinase (ERK) and p38 signaling pathways were involved in the proliferation of A549 cells. After CAC1 siRNA treatment, p-ERK1/2 levels decreased, and meanwhile p-p38 level increased, A549 cell proliferation increased when ERK1/2 signaling is activated by PMA. Our findings demonstrated that CAC1 promoted the proliferation of human lung cancer A549 cells with activation of ERK1/2 signaling pathways, suggesting a potential cure target for treatment of human lung cancer.

  12. HESA The Heterodox Economics Student Association in the University of Utah was established in order to promote and preserve the tradition of radical political economy.

    E-Print Network [OSTI]

    Simons, Jack

    in order to promote and preserve the tradition of radical political economy. Check out our blog! HESA

  13. TWIST1 associates with NF-kappaB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    subunit RELA via carboxyl-terminal WR domain to promote cellthrough the TWIST1 carboxy-terminal WR (Trp-Arg) domainis dependent on the C- terminal WR domain, through which

  14. SGTA Recognizes a Noncanonical Ubiquitin-like Domain in the Bag6-Ubl4A-Trc35 Complex to Promote Endoplasmic Reticulum-Associated Degradation

    E-Print Network [OSTI]

    Xu, Yue; Cai, Mengli; Yang, Yingying; Huang, Lan; Ye, Yihong

    2012-01-01T23:59:59.000Z

    reticulum-associated degradation. Nat Rev Mol Cell Biol.ER-associated protein degradation/ERAD/retrotranslocation;Ufd1-Npl4 ATPase complex for degradation by the proteasome (

  15. 2014 Newly Tenured and Promoted Faculty College of Agriculture, Human, and Natural Resource Sciences

    E-Print Network [OSTI]

    Collins, Gary S.

    . Whidbee Promote Professor and Associate Dean The Edward R. Murrow College of Communication Name Action Grant and Promote Associate Professor Libraries Name Action Title Corey M. Johnson Promote Librarian IV

  16. Functional Promoter Variant rs2868371 of HSPB1 Is Associated With Risk of Radiation Pneumonitis After Chemoradiation for Non-Small Cell Lung Cancer

    SciTech Connect (OSTI)

    Pang, Qingsong [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States) [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Department of Radiation Oncology and Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin (China); Wei, Qingyi [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States); Xu, Ting [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Yuan, Xianglin [Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan (China)] [Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan (China); Lopez Guerra, Jose Luis [Department of Medicine, Universitat Autònoma de Barcelona (Spain)] [Department of Medicine, Universitat Autònoma de Barcelona (Spain); Levy, Lawrence B. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Liu, Zhensheng [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States); Gomez, Daniel R. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Zhuang, Yan [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States); Wang, Li-E. [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States); Mohan, Radhe [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States); Komaki, Ritsuko [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Liao, Zhongxing, E-mail: zliao@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)

    2013-04-01T23:59:59.000Z

    Purpose: To date, no biomarkers have been found to predict, before treatment, which patients will develop radiation pneumonitis (RP), a potentially fatal toxicity, after chemoradiation for lung cancer. We investigated potential associations between single nucleotide polymorphisms (SNPs) in HSPB1 and risk of RP after chemoradiation for non-small cell lung cancer (NSCLC). Methods and Materials: Subjects were patients with NSCLC treated with chemoradiation at 1 institution. The training data set comprised 146 patients treated from 1999 to July 2004; the validation data set was 125 patients treated from August 2004 to March 2010. We genotyped 2 functional SNPs of HSPB1 (rs2868370 and rs2868371) from all patients. We used Kaplan-Meier analysis to assess the risk of grade ?2 or ?3 RP in both data sets and a parametric log-logistic survival model to evaluate the association of HSPB1 genotypes with that risk. Results: Grade ?3 RP was experienced by 13% of those with CG/GG and 29% of those with CC genotype of HSPB1 rs2868371 in the training data set (P=.028); corresponding rates in the validation data set were 2% CG/GG and 14% CC (P=.02). Univariate and multivariate analysis confirmed the association of CC of HSPB1 rs2868371 with higher risk of grade ?3 RP than CG/GG after adjustment for sex, age, performance status, and lung mean dose. This association was validated both in the validation data set and with Harrell's C statistic. Conclusions: The CC genotype of HSPB1 rs2868371 was associated with severe RP after chemoradiation for NSCLC.

  17. ORISE: Health Promotion and Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Health Promotion and Outreach Health Promotion & Outreach The Oak Ridge Institute for Science and Education (ORISE) provides health promotion and outreach support to government...

  18. Geothermal: Promotional Video

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Promotional Video Geothermal Technologies Legacy Collection HelpFAQ | Site Map | Contact Us HomeBasic Search About Publications Advanced Search New Hot Docs News Related Links...

  19. High expression Zymomonas promoters

    DOE Patents [OSTI]

    Viitanen, Paul V. (West Chester, PA); Tao, Luan (Havertown, PA); Zhang, Yuying (New Hope, PA); Caimi, Perry G. (Kennett Square, PA); McCole, Laura (East Fallowfield, PA): Zhang, Min (Lakewood, CO); Chou, Yat-Chen (Lakewood, CO); McCutchen, Carol M. (Wilmington, DE); Franden, Mary Ann (Centennial, CO)

    2011-08-02T23:59:59.000Z

    Identified are mutants of the promoter of the Z. mobilis glyceraldehyde-3-phosphate dehydrogenase gene, which direct improved expression levels of operably linked heterologous nucleic acids. These are high expression promoters useful for expression of chimeric genes in Zymomonas, Zymobacter, and other related bacteria.

  20. 2014 Local Clinical Promotion Committee College Composition of LCPC SecretaryLocal Clinical Promotion Chair of LCPC

    E-Print Network [OSTI]

    Chen, Ying

    2014 Local Clinical Promotion Committee College Composition of LCPC SecretaryLocal Clinical Butterworth A/Prof Gavin Huttley 2014 University Clinical Promotion Committee Composition of UCPC Professor Barnard, Associate Dean, Rural Clinical School, ANU Medical School Secretariat Kylie Clark and Nathalie

  1. counselling health promotion

    E-Print Network [OSTI]

    health and counselling services health promotion 10 Ways to get active Most people find that power into your day. 1. take it outside. Ride a bike, go skating, fly a kite, throw a frisbee, kick chats for a power walk with friends and catch up face to face. 6. get involved locally. Join sports

  2. Coordinating and promoting effective

    E-Print Network [OSTI]

    1 I Coordinating and promoting effective protection and restoration of fish, wildlife Nation Idaho Department of Fish and Game Kootenai Tribe of Idaho Montana Department of Fish, Wildlife and Parks National Marine Fisheries Service Nez Perce Tribe Oregon Department of Fish and Wildlife Shoshone

  3. Health Behavior Health Promotion -Prevention

    E-Print Network [OSTI]

    Meagher, Mary

    chronic disease complications Improve quality of life Reduce health care costs #12;ImpactHealth Behavior Health Promotion - Prevention Modification of Health Attitudes and Health Behavior #12;Health Promotion: An Overview Basic philosophy Good health = individual and collective goal

  4. Antonya Sanders-Promoting

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041cloth DocumentationProductsAlternative FuelsSanta3 Tableimpurity ionAntonya Sanders-Promoting

  5. Commercial Current Promotions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would like submit the following commentsCurrent-Promotions Sign In About |

  6. Promoters and proteins from Clostridium thermocellum and uses thereof

    DOE Patents [OSTI]

    Wu, J. H. David; Newcomb, Michael

    2012-11-13T23:59:59.000Z

    The present invention relates to an inducible and a high expression nucleic acid promoter isolated from Clostridium thermocellum. These promoters are useful for directing expression of a protein or polypeptide encoded by a nucleic acid molecule operably associated with the nucleic acid promoters. The present invention also relates to nucleic acid constructs including the C. thermocellum promoters, and expression vectors and hosts containing such nucleic acid constructs. The present invention also relates to protein isolated from Clostridium thermocellum, including a repressor protein. The present invention also provides methods of using the isolated promoters and proteins from Clostridium thermocellum, including methods for directing inducible in vitro and in vivo expression of a protein or polypeptide in a host, and methods of producing ethanol from a cellulosic biomass.

  7. Photovoltaic module with adhesion promoter

    DOE Patents [OSTI]

    2013-10-08T23:59:59.000Z

    Photovoltaic modules with adhesion promoters and methods for fabricating photovoltaic modules with adhesion promoters are described. A photovoltaic module includes a solar cell including a first surface and a second surface, the second surface including a plurality of interspaced back-side contacts. A first glass layer is coupled to the first surface by a first encapsulating layer. A second glass layer is coupled to the second surface by a second encapsulating layer. At least a portion of the second encapsulating layer is bonded directly to the plurality of interspaced back-side contacts by an adhesion promoter.

  8. DTU Synthetic Promoter Library Standard

    E-Print Network [OSTI]

    Fortuna, Patrick

    2010-12-04T23:59:59.000Z

    The purpose of this RFC is to outline a method for generating a BioBrick compatible Synthetic Promoter Library (SPL) within bacteria in order to fine-tune the expression of BioBrick parts and devices.

  9. Microsoft PowerPoint - RFA_EIA_conference_2009.ppt

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for On-Highway4,1,50022,3,,,,6,1,9,1,50022,3,,,,6,1,Decade EnergyTennesseeYearUndergroundCubicDecadeFeet)Proved O i

  10. Extracorporeal membrane oxygenation promotes long chain fatty...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    membrane oxygenation promotes long chain fatty acid oxidation in the immature swine heart in vivo. Extracorporeal membrane oxygenation promotes long chain fatty acid oxidation...

  11. ORISE: Iddins promoted to associate director of Radiation Emergency

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's Possible for Renewable Energy:Nanowire3627 FederalTransformers1Thomas LiuYashema Mack

  12. The design of effective policies for the promotion of sustainable construction materials

    E-Print Network [OSTI]

    Kua, Harn Wei, 1971-

    2006-01-01T23:59:59.000Z

    This research explores the associated effects of policy tools employed to promote sustainable building materials. By comparing the original motivations and intended effects of these policies and their actual outcome, and ...

  13. Service Promotion -Diffusion Raphale LOMBARD

    E-Print Network [OSTI]

    Pellier, Damien

    Service Promotion - Diffusion Raphaële LOMBARD Editions L'Harmattan - 5 Rue de l'Ecole Polytechnique ­ 75005 Paris Tél 01.40.46.79.23 ­ mail : raphaele.lombard@harmattan.fr La mondialisation avance à complémentaires BON DE COMMANDE A retourner à L'HARMATTAN, 7 rue de l'�cole Polytechnique 75005 Paris Veuillez me

  14. Aging and Place: Building Health Promotion into

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    Aging and Place: Building Health Promotion into Long-Term Care IHRP Brownbag May 21, 2013 Naoko-being in social contexts. ­ To improve quality of services by building health promotion into long-term care. #12 ­ U.S. 3. Building health promotion into long-term care ­ Why important? ­ Challenges

  15. Nutr Cancer . Author manuscript Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Nutr Cancer . Author manuscript Page /1 9 Freeze-dried ham promotes azoxymethane-induced mucin and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads

  16. Promoting Employment Across Kansas (PEAK) (Kansas)

    Broader source: Energy.gov [DOE]

    Promoting Employment Across Kansas (PEAK) allows for the retention of employee payroll withholding taxes for qualified companies or third parties performing services on behalf of such companies....

  17. Extracellular Proteins Promote Zinc Sulfide Aggregation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and metals, particularly how organics affect mobility, and its potential for bioremediation. It is known that some organics promote aggregation. Amine-bearing molecules, for...

  18. Promoting Self Directed Learning 1 Running head: PROMOTING SELF DIRECTED LEARNING

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    as incompatible. This is due to the origins of both types of learning environments which, when consideredPromoting Self Directed Learning 1 Running head: PROMOTING SELF DIRECTED LEARNING Promoting Self Directed Learning in Simulation Based Discovery Learning Environments through Intelligent Support Koen

  19. Brain dynamics promotes function Carlos Lourenco

    E-Print Network [OSTI]

    Lisboa, Universidade Técnica de

    Brain dynamics promotes function Carlos Louren¸co 1 Faculty of Sciences of the University of Lisbon, 1049-001 Lisboa - Portugal Abstract. Dynamical structure in the brain promotes biological func- tion. Computational scientists have new opportunities to receive 'algorithmic' inspiration from brain processes

  20. Learning Lessons to Promote Certification and

    E-Print Network [OSTI]

    Financing and Investment in Companies Engaged in Destructive or Illegal Logging in Indonesia 14 2Learning Lessons to Promote Certification and Combat Illegal Logging in Indonesia September 2003;Learning Lessons to Promote Certification and Combat Illegal Logging in Indonesia September 2003 to June

  1. Chapter 10: Computational Methods for Promoter Recognition

    E-Print Network [OSTI]

    eukaryotic (polII or protein-coding) gene, it contains a core promoter about 100 bp centered around TATA binding proteins have been discovered in a few specific types of cells, see Holmes and Tjian 2000 in Novina and Roy 1996). Many "housekeeping gene" core promoters appear to lack both TATA a

  2. The current use of studies on promoters and cocarcinogens in quantitative risk assessment. Environ. Health Perspect

    E-Print Network [OSTI]

    J. F. Stara; D. Mukerjee; R. Mcgaughy; T P. Durkint; M. L. Dourson

    1983-01-01T23:59:59.000Z

    Several of the priority pollutants discussed in EPA's Ambient Water Quality Criteria documents have been reported to have promotion or cocarcinogenic activity. For example, phenol appears to have tumor-promoting activity in mice when repeatedly applied after initiation with either 7,12-dimethyl-1,2-benzanthracene (DMBA) or benzo(a)pyrene (BaP). Similarly, it has been reported that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a potent promoter of liver tumors as well as a cocarcinogen. However, in developing guidelines to derive ambient water quality criteria, it became apparent that satisfactory approaches had not been developed for using promotion/cocarcinogen data in human health risk estimation, nor were available promotion and/or cocarcinogen data on individual chemicals strong enough to permit a defensible quantitative risk estimation, if such approaches had existed. For this reason, the criteria derived for pollutants with reported promotion/cocarcinogenic activities were based on approaches for carcinogenic (e.g., TCDD), toxic (e.g., fluoranthene) or organoleptic effects (e.g., 2,4-dichlorophenol). Nonetheless, with advances in studies on both the biological mechanisms and dose/response patterns of promoters and cocarcinogens, it may be possible to develop a scientifically valid quantitative approach to use this type of data for derivation of ambient water quality criteria or other risk assessments. Some progress toward this goal and the problems associated with this effort are discussed.

  3. Home Energy Appraisal Form of the Texas Association of Builders 

    E-Print Network [OSTI]

    Moore, J.

    1986-01-01T23:59:59.000Z

    efficiency . INTRODUCTION The Texas Association of Builders (TAB) is committed to promoting the building of energy effic- ient homes to preserve our limited supplies of fossil fuels and to produce homes that are efficient to operate. Over the past ten...

  4. PREVENTING ABSENTEEISM AND PROMOTING RESILIENCE AMONG HEALTH CARE WORKERS IN

    E-Print Network [OSTI]

    PREVENTING ABSENTEEISM AND PROMOTING RESILIENCE AMONG HEALTH CARE WORKERS IN BIOLOGICAL Preventing Absenteeism and Promoting Resilience among Health Care Workers in Biological Emergencies A and Promoting Resilience among Health Care Workers in Biological Emergencies A. Lesperance J. Miller1 1

  5. Forest County Potawatomi Tribe Cuts Emissions, Promotes Green...

    Office of Environmental Management (EM)

    Emissions, Promotes Green Growth Forest County Potawatomi Tribe Cuts Emissions, Promotes Green Growth February 23, 2012 - 6:29pm Addthis The Forest County Potawatomi Tribe's solar...

  6. Country report on advertising and promotion bans - Croatia

    E-Print Network [OSTI]

    Hrabak-Zerbajic, Dr. Vlasta

    2004-01-01T23:59:59.000Z

    Country report on advertising and promotion bans – Croatiaand promotion bans – Croatia Dr Vlasta Hrabak-Zerbajicbeen grown and consumed in Croatia. In the last century the

  7. LESSONS LEARNED FROM RECENT PROMOTION STRATEGIES FOR ELECTRICITY

    E-Print Network [OSTI]

    LESSONS LEARNED FROM RECENT PROMOTION STRATEGIES FOR ELECTRICITY FROM RENEWABLES IN EU COUNTRIES and OPTRES. Finally, the lessons learned from recent promotion strategies for electricity from renewables

  8. Sandia National Laboratories: A Model for the Nation: Promoting...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ClimateECClimateA Model for the Nation: Promoting Education and Innovation in Vermont's Electricity Sector A Model for the Nation: Promoting Education and Innovation in Vermont's...

  9. Promotion of Hydrogen Release from Ammonia Borane with Mechanically...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Promotion of Hydrogen Release from Ammonia Borane with Mechanically Activated Hexagonal Boron Nitride. Promotion of Hydrogen Release from Ammonia Borane with Mechanically Activated...

  10. Promoting a Green Economy through Clean Transportation Alternatives...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    D.C. tiarravt052ebert2010p.pdf More Documents & Publications Promoting a Green Economy through Clean Transportation Alternatives Promoting a Green Economy through Clean...

  11. Energy 101: Promoting Energy Education in the Nation's Colleges...

    Energy Savers [EERE]

    101: Promoting Energy Education in the Nation's Colleges and Universities Energy 101: Promoting Energy Education in the Nation's Colleges and Universities June 25, 2014 - 2:46pm...

  12. United States, Australia, and Iceland to Promote Geothermal Energy...

    Office of Environmental Management (EM)

    United States, Australia, and Iceland to Promote Geothermal Energy United States, Australia, and Iceland to Promote Geothermal Energy August 28, 2008 - 12:43pm Addthis Photo of...

  13. Tips and Tools for Promoting Your Energy Efficiency Project ...

    Broader source: Energy.gov (indexed) [DOE]

    Tips and Tools for Promoting Your Energy Efficiency Project (Text Version) Tips and Tools for Promoting Your Energy Efficiency Project (Text Version) Courtney: Hello, everyone, and...

  14. Building Bridges: Federal Agencies Join Forces to Promote Sustainable...

    Broader source: Energy.gov (indexed) [DOE]

    promote the development of prosperous and resilient tribal communities by: 1. Promoting sustainable economic development; 2. Supporting greater access to and control over...

  15. Promoting a Green Economy through Clean Transportation Alternatives...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Peer Evaluation arravt052tiebert2011p.pdf More Documents & Publications Promoting a Green Economy through Clean Transportation Alternatives Promoting a Green Economy through...

  16. Promoting a Green Economy through Clean Transportation Alternatives...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Promoting a Green Economy through Clean Transportation Alternatives Promoting a Green Economy through Clean Transportation Alternatives Town of Hempstead: Project Energy,...

  17. Senegal-GTZ Programme to Promote Rural Electrification and a...

    Open Energy Info (EERE)

    Promote Rural Electrification and a Sustainable Supply of Domestic Fuel Jump to: navigation, search Logo: Senegal-GTZ Programme to promote rural electrification and a sustainable...

  18. Utility Partnerships Webinar Series: State Policies to Promote...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Utility Partnerships Webinar Series: State Policies to Promote Utility Energy Efficiency Programs Utility Partnerships Webinar Series: State Policies to Promote Utility Energy...

  19. INFORMATION FOR 2014 ACADEMIC PROMOTIONS ROUND Academic Promotions Policy: https://policies.anu.edu.au/ppl/document/ANUP_000363

    E-Print Network [OSTI]

    Botea, Adi

    INFORMATION FOR 2014 ACADEMIC PROMOTIONS ROUND Academic Promotions Policy: https://policies.anu.edu.au/ppl/document/ANUP_000363 Academic Promotions Procedure: https://policies.anu.edu.au/ppl/document/ANUP_000624 Academic

  20. Considerations in PromotingConsiderations in Promoting Markets for Sustainable EnergyMarkets for Sustainable Energy

    E-Print Network [OSTI]

    ! Energy pricing and taxation policies ! Institutional structures ! Regulatory policies ! Business sizeConsiderations in PromotingConsiderations in Promoting Markets for Sustainable EnergyMarkets for Sustainable Energy Technologies in DevelopingTechnologies in Developing CountriesCountries #12;21 May 2003

  1. Promotion and resignation in employee networks

    E-Print Network [OSTI]

    Yuan, Jia; Gao, Jian; Zhang, Linyan; Wan, Xue-Song; Yu, Xiao-Jun; Zhou, Tao

    2015-01-01T23:59:59.000Z

    Enterprises have put more and more emphasis on data analysis so as to obtain effective management advices. Managers and researchers are trying to dig out the major factors that lead to employees' promotion and resignation. Most previous analyses were based on questionnaire survey, which usually consists of a small fraction of samples and contains biases caused by psychological defense. In this paper, we successfully collect a data set consisting of all the employees' work-related interactions (action network, AN for short) and online social connections (social network, SN for short) of a company, which inspires us to reveal the correlations between structural features and employees' career development, namely promotion and resignation. Through statistical analysis and prediction, we show that the structural features of both AN and SN are correlated and predictive to employees' promotion and resignation, and the AN has higher correlation and predictability. More specifically, the in-degree in AN is the most re...

  2. Universal light-switchable gene promoter system

    DOE Patents [OSTI]

    Quail, Peter H.; Huq, Enamul; Tepperman, James; Sato, Sae

    2005-02-22T23:59:59.000Z

    An artificial promoter system that can be fused upstream of any desired gene enabling reversible induction or repression of the expression of the gene at will in any suitable host cell or organisms by light is described. The design of the system is such that a molecule of the plant photoreceptor phytochrome is targeted to the specific DNA binding site in the promoter by a protein domain that is fused to the phytochrome and that specifically recognizes this binding site. This bound phytochrome, upon activation by light, recruits a second fusion protein consisting of a protein that binds to phytochrome only upon light activation and a transcriptional activation domain that activates expression of the gene downstream of the promoter.

  3. Preserving the Past. Promoting the Future. JACKSON. COOL. CONNECTED.

    E-Print Network [OSTI]

    Baskaran, Mark

    Preserving the Past. Promoting the Future. JACKSON. COOL. CONNECTED. JACKSON. COOL. CONNECTED. Preserving the Past. Promoting the Future. #12;Preserving the Past. Promoting the Future. 2 JACKSON. COOL the Past. Promoting the Future. 3 JACKSON. COOL. CONNECTED. Table of Contents Acknowledgements 4 Forward 5

  4. Identification of Human Gene Core Promoters Michael Q. Zhang1

    E-Print Network [OSTI]

    Identification of Human Gene Core Promoters in Silico Michael Q. Zhang1 Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 USA Identification of the 5 -end of human genes requires--CorePromoter. Our experiments indicate that when given a 1- to 2-kb extended promoter, CorePromoter will correctly

  5. 5.16: LIBRARY RETENTION, TENURE AND PROMOTIONS CRITERIA Approved by Library Faculty, Department Co-Chairs, and University Librarian 9/21/06

    E-Print Network [OSTI]

    5.16: LIBRARY RETENTION, TENURE AND PROMOTIONS CRITERIA Approved by Library Faculty, Department Co in Library Assignment and amplifications are noted below for Professional Achievement and Growth & Research Libraries (ACRL), the national organization associated with academic librarians. For tenure

  6. Promotion of Efficient Use of Energy

    SciTech Connect (OSTI)

    Harry Misuriello; DOE Project Officer - Keith Bennett

    2006-01-25T23:59:59.000Z

    The Department of Energy funded the Alliance to Save Energy to promote the efficient use of energy under a multiyear cooperative agreement. This funding allowed the Alliance to be innovative and flexible in its program development, and to initiate and enhance projects it would otherwise not have been able to pursue. The program period was 1999 through 2004. The mission of the Alliance to Save Energy is to promote energy efficiency domestically and worldwide. The Alliance followed this mission by working closely with consumers, government, policy makers, and energy efficient product and service providers. The projects that were initiated by the Alliance included communication and consumer education, policy analysis and research, the promotion of interaction among the energy efficiency industry, and international energy efficiency programs. The funding from the Department of Energy allowed the Alliance to study new issues in energy efficiency, draw public attention to those issues, and create targeted programs, such as the Efficient Windows Collaborative or the Green Schools program, which now function on their own to promote energy efficiency in important areas.

  7. Aquatic eutrophication promotes pathogenic infection in amphibians

    E-Print Network [OSTI]

    Johnson, Pieter

    Aquatic eutrophication promotes pathogenic infection in amphibians Pieter T. J. Johnson* , Jonathan-scale agents of environmental change affect host­pathogen interactions. Acceler- ated eutrophication of aquatic experimental evidence linking eutrophication and disease in a multihost parasite system. The trematode parasite

  8. Health and Counselling Services SFU Health Promotion

    E-Print Network [OSTI]

    Health and Counselling Services SFU Health Promotion A division of Student Services HEALTHY CAMPUS COMMUNITY 2 0 1 3 R E P O R T #12;Dr. Tim Rahilly Dr. Nancy Johnston FOREWORD The health and well. We have a responsibility as a caring community to create a setting that not only supports students

  9. FISK ASSOCIATES

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA group currentBradleyTableSelling7111AWell:F E ," POST RmDIAL8FISK ASSOCIATES

  10. DEPARTMENT OF AGRICULTURAL ECONOMICS Faculty Tenure and Promotion Evaluation Procedures

    E-Print Network [OSTI]

    Behmer, Spencer T.

    DEPARTMENT OF AGRICULTURAL ECONOMICS Faculty Tenure and Promotion Evaluation Procedures Revised............................................20 2 #12;DEPARTMENT OF AGRICULTURAL ECONOMICS Faculty Tenure and Promotion Evaluation Procedures November 2013 #12;Table of Contents I. The Evaluation Process

  11. Promoting Sustainability Awareness through Energy Engaged Virtual Communities of Construction

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Promoting Sustainability Awareness through Energy Engaged Virtual Communities of Construction to demolition. Sustainability knowledge is #12;Promoting Sustainability Awareness through Energy EngagedH@cf.ac.uk Abstract. Sustainability requires the engagement of every single constituent of the "building" product

  12. Improving promotional effectiveness through supplier-retailer collaboration

    E-Print Network [OSTI]

    Kapur, Gautam, M. Eng. Massachusetts Institute of Technology

    2007-01-01T23:59:59.000Z

    In the consumer products industry, retail chains and manufacturers run promotions to maintain consumer and brand loyalty. The two major issues in planning and executing promotions are to accurately forecast demand and to ...

  13. Outreach Letter Template for Clean Cities Coordinators Promoting...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Letter Template for Clean Cities Coordinators Promoting the Workplace Charging Challenge ccoutreachlettertemplate-final.docx More Documents & Publications Outreach Letter...

  14. Insights into anaphase promoting complex TPR subdomain assembly from a CDC26?APC6 structure

    SciTech Connect (OSTI)

    Wang, Jing; Dye, Billy T.; Rajashankar, Kanagalaghatta R.; Kurinov, Igor; Schulman, Brenda A.; (Cornell); (SJCH)

    2009-12-01T23:59:59.000Z

    The multisubunit anaphase promoting complex (APC) is an essential cell-cycle regulator. Although CDC26 is known to have a role in APC assembly, its molecular function has remained unclear. Biophysical, structural and genetic studies presented here reveal that CDC26 stabilizes the structure of APC6, a core TPR protein required for APC integrity. Notably, CDC26-APC6 association involves an intermolecular TPR mimic composed of one helix from each protein.

  15. Promoting alternative fuels in Philadelphia. Final report

    SciTech Connect (OSTI)

    NONE

    1996-04-16T23:59:59.000Z

    The US Department of Energy`s grant to Citizens Fund was designed to support a grassroots organizing campaign, local coalition building and media activity initially focused on getting the Southeastern Pennsylvania Transit Authority (SEPTA) to acquire clean burning alternative fueled buses (e.g. natural gas). In addition, Citizens Fund through Pennsylvania Citizen Action would become involved in the Philadelphia Clean Cities organization sponsored by the City of Philadelphia through a DOE grant. The city reached out to a substantial number of organizations and community leaders and actively worked to get out the message on the need to promote and use alternatively-fueled vehicles. This report summarizes these activities.

  16. Extracellular Proteins Promote Zinc Sulfide Aggregation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power AdministrationField8,Dist. Category UC-l 1,EnergyExploring theExtracellular Proteins Promote

  17. Promoting Sustainability on a Global Scale

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOrigin of ContaminationHubs+ ReportEnergy National SolarPublicationsof EnergyPromoting

  18. The oncoprotein HBXIP upregulates PDGFB via activating transcription factor Sp1 to promote the proliferation of breast cancer cells

    SciTech Connect (OSTI)

    Zhang, Yingyi; Zhao, Yu; Li, Leilei; Shen, Yu; Cai, Xiaoli [Department of Biochemistry, College of Life Sciences, Nankai University, Tianjin 300071 (China)] [Department of Biochemistry, College of Life Sciences, Nankai University, Tianjin 300071 (China); Zhang, Xiaodong, E-mail: zhangxd@nankai.edu.cn [Department of Cancer Research, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071 (China)] [Department of Cancer Research, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071 (China); Ye, Lihong, E-mail: yelihong@nankai.edu.cn [Department of Biochemistry, College of Life Sciences, Nankai University, Tianjin 300071 (China)] [Department of Biochemistry, College of Life Sciences, Nankai University, Tianjin 300071 (China)

    2013-05-03T23:59:59.000Z

    Highlights: •HBXIP is able to upregulate the expression of PDGFB in breast cancer cells. •HBXIP serves as a coactivator of activating transcription factor Sp1. •HBXIP stimulates the PDGFB promoter via activating transcription factor Sp1. •HBXIP promotes the proliferation of breast cancer cell via upregulating PDGFB. -- Abstract: We have reported that the oncoprotein hepatitis B virus X-interacting protein (HBXIP) acts as a novel transcriptional coactivator to promote proliferation and migration of breast cancer cells. Previously, we showed that HBXIP was able to activate nuclear factor-?B (NF-?B) in breast cancer cells. As an oncogene, the platelet-derived growth factor beta polypeptide (PDGFB) plays crucial roles in carcinogenesis. In the present study, we found that both HBXIP and PDGFB were highly expressed in breast cancer cell lines. Interestingly, HBXIP was able to increase transcriptional activity of NF-?B through PDGFB, suggesting that HBXIP is associated with PDGFB in the cells. Moreover, HBXIP was able to upregulate PDGFB at the levels of mRNA, protein and promoter in the cells. Then, we identified that HBXIP stimulated the promoter of PDGFB through activating transcription factor Sp1. In function, HBXIP enhanced the proliferation of breast cancer cells through PDGFB in vitro. Thus, we conclude that HBXIP upregulates PDGFB via activating transcription factor Sp1 to promote proliferation of breast cancer cells.

  19. An Economic Evaluation of the Hass Avocado Promotion Order’s First Five Years

    E-Print Network [OSTI]

    Carman, Hoy; Li, Lan; Sexton, Richard J.

    2009-01-01T23:59:59.000Z

    Inc. , 2005. California Avocado Commission. “Annualannual- reports. California Avocado Commission. “BusinessPromotion Programs: The Hass Avocado Promotion and Research

  20. Innovative policies to promote renewable energy

    SciTech Connect (OSTI)

    Harvey, H. [Energy Foundation, San Francisco, CA (United States)

    1993-11-01T23:59:59.000Z

    The subject of this paper is innovative policies to promote renewable energy. The renewable energy industry has made great progress in the last decade. Prices have dropped four-fold or more, and reliability has increased dramatically. By most measures, then, the renewable energy industry should be poised to become a mainstream success. But upon closer examination, it appears instead that society may snatch defeat from the jaws of victory. Unless something changes, and soon, dozens of promising renewable technologies may stumble and fall. An exploding population, a build-up of CO{sub 2} threatening to cause global warming, extensive oil spills and oil fires, and acid rain make it imperative to preserve this option. The author looks at what drives this situation, where on the one hand renewable energy technologies are more cost-effective than ever, and on the other society is not ready to purchase them in sufficient quantities to overcome these problems.

  1. RFA-14-0001 - In the Matter of Commonwealth Oil Refining Company...

    Broader source: Energy.gov (indexed) [DOE]

    both programs would reduce the dependence of Puerto Rican consumers on high cost imported oil and refined petroleum products and that, consequently, both programs were consistent...

  2. RFA-14-0002 - In the Matter of Highway Oil, Inc. | Department of Energy

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic2 OPAM615_CostNSAR - TProcuring SolarNo.

  3. RFA-14-0001 - In the Matter of Commonwealth Oil Refining Company,

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn April 23, 2014, an OHASeptember 2010In addition to 1 |D I S P U

  4. for Nuclear Energy Graduate Fellowships Subject: Integrated University Program: Graduate Fellowship Program - RFA

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual Siteof Energy 2, 2015Visiting8.pdf flash2004-18.pdfflash2007-21Attachment.pdfBPA

  5. for Nuclear Energy Undergraduate Scholarships Subject: Integrated University Program: Undergraduate Scholarship Program - RFA

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual Siteof Energy 2, 2015Visiting8.pdf flash2004-18.pdfflash2007-21Attachment.pdfBPA1-14 for

  6. Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis

    E-Print Network [OSTI]

    Lertpiriyapong, Kvin

    Objectives: Gastric colonisation with intestinal flora (IF) has been shown to promote Helicobacter pylori (Hp)-associated gastric cancer. However, it is unknown if the mechanism involves colonisation with specific or diverse ...

  7. PROMOTING ENERGY CONSERVATION THROUGH OCCUPATIONAL LICENSURE: A FEASIBILITY STUDY

    E-Print Network [OSTI]

    Wilms, W.W.

    2010-01-01T23:59:59.000Z

    Interim Criteria for Energy Conservation in New Buildings",Robert and others, "Energy Conservation Program Guide forDivision Promoting Energy Conservation Through Occupational

  8. Interactions of p53 and p73 with human promoters

    E-Print Network [OSTI]

    Huang, Vera

    2007-01-01T23:59:59.000Z

    occupied promoters (FDR MAP PIR_KEYWORDSSP_PIR_KEYWORDSSP_PIR_KEYWORDS GOTERM_BP_ALL SP_PIR_KEYWORDS SP_PIR_

  9. Secretary Chu Announces New Efforts to Promote Clean Energy in...

    Broader source: Energy.gov (indexed) [DOE]

    energy projects on tribal lands that will help save energy and money, expand the use of renewable energy resources, and promote economic development for tribal communities....

  10. Supporting Information Unexpected Role of Activated Carbon in Promoting

    E-Print Network [OSTI]

    Huang, Ching-Hua

    Supporting Information Unexpected Role of Activated Carbon in Promoting Transformation of Secondary. (City of Industry, CA), Siemens Aquacarb carbon (AqC) from Siemens Water Technologies (Warrendale, PA

  11. Economic Incentives to Promote Innovation in Healthcare Delivery

    E-Print Network [OSTI]

    Luft, Harold S.

    2009-01-01T23:59:59.000Z

    U E S IN ORTHOPAEDIC SURGERY Economic Incentives to Promoteservice offers no economic incentives for clinicians to ef?10, October 2009 Economic Incentives Promoting Innovation

  12. Utility Partnerships Webinar Series: State Policies to Promote...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    State Policies to Promote Utility Energy Efficiency Programs December 7, 2010 Industrial Technologies Program eere.energy.gov Speakers and Topics: * Franklin Energy Services, LLC,...

  13. Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    wells containing either 40 ng/ml SDF-1 con- ditioned mediumor control medium lacking SDF-1 and incubated for 22 hours.and grown in the presence of SDF-1 (the ligand for the CXCR4

  14. DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

    E-Print Network [OSTI]

    Laplante, Mathieu

    DEP domain-containing mTOR-interacting protein (DEPTOR) inhibits the mechanistic target of rapamycin (mTOR), but its in vivo functions are unknown. Previous work indicates that Deptor is part of the Fob3a quantitative trait ...

  15. Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    breast cancer cell lines (MDA-MB231 and T47D) caused a smallin breast cancer cells (MDA-MB231 and T47D) resulted in a3H-Thymidine incorporation MDA-MB231, T47D, and AG1132B

  16. Regulatory Promotion of Emergent CCS Technology

    SciTech Connect (OSTI)

    Davies, Lincoln; Uchitel, Kirsten; Johnson, David

    2014-01-01T23:59:59.000Z

    Despite the growing inevitability of climate change and the attendant need for mitigation strategies, carbon capture and sequestration (CCS) has yet to gain much traction in the United States. Recent regulatory proposals by the U.S. Environmental Protection Agency (EPA), limited in scope to new-build power plants, represent the only significant policy initiative intended to mandate diffusion of CCS technology. Phase I of this Project assessed barriers to CCS deployment as prioritized by the CCS community. That research concluded that there were four primary barriers: (1) cost, (2) lack of a carbon price, (3) liability, and (4) lack of a comprehensive regulatory regime. Phase II of this Project, as presented in this Report, assesses potential regulatory models for CCS and examines where those models address the hurdles to diffusing CCS technology identified in Phase I. It concludes (1) that a CCS-specific but flexible standard, such as a technology performance standard or a very particular type of market-based regulation, likely will promote CCS diffusion, and (2) that these policies cannot work alone, but rather, should be combined with other measures, such as liability limits and a comprehensive CCS regulatory regime.

  17. ORIGINAL ARTICLE Diatom assemblages promote ice formation in large

    E-Print Network [OSTI]

    Lee Jr., Richard E.

    ORIGINAL ARTICLE Diatom assemblages promote ice formation in large lakes NA D'souza1,3 , Y evidence for the directed formation of ice by planktonic communities dominated by filamentous diatoms sampled from the ice-covered Laurentian Great Lakes. We hypothesize that ice formation promotes attachment

  18. Marketing and promoting solar water heaters to home builders

    SciTech Connect (OSTI)

    Keller, C.; Ghent, P.

    1999-12-06T23:59:59.000Z

    This is the final report of a four-task project to develop a marketing plan designed for businesses interested in marketing solar water heaters in the new home industry. This report outlines suggested marketing communication materials and other promotional tools focused on selling products to the new home builder. Information relevant to promoting products to the new home buyer is also included.

  19. Standards for Hiring, Promotion, and Tenure Department of Computer Science

    E-Print Network [OSTI]

    Heller, Barbara

    Standards for Hiring, Promotion, and Tenure Department of Computer Science Illinois Institute and September 28, 2005 The Department of Computer Science is committed to hiring, nurturing, and promoting and tenure of Category II faculty members in the Department of Computer Science. It is meant to supplement

  20. The HMS Promotion and Review Board The HMS Promotion and Review Board (PRB) is a Standing Committee of the

    E-Print Network [OSTI]

    Paulsson, Johan

    The HMS Promotion and Review Board The HMS Promotion and Review Board (PRB) is a Standing Committee. PRB members are appointed by the Dean for Medical Education and include preclinical and clinical Resources faculty may also consult to the Board. The PRB considers all difficulties that arise with student

  1. On the thermodynamic stability of hydrogen hydrates in the presence of promoter molecules

    SciTech Connect (OSTI)

    Nakayama, Takato; Matsumoto, Masakazu; Tanaka, Hideki [Department of Chemistry, Faculty of Science, Okayama University 3-1-1 Tsushima-naka, Kitaku, Okayama 700-8530 (Japan)

    2013-12-10T23:59:59.000Z

    Cage occupancies of hydrogen molecules in a clathrate hydrate have been examined by means of semi-grand canonical Monte Carlo simulations where hydrogen molecules enter into or leave from it in the presence of promoter species. This kind of simulation allows to evaluate the thermodynamic stability via the chemical potential of water at a given temperature and pressure. In order to make a better estimation of the chemical potential, we adopt a different standard state from the corresponding empty one. It is revealed that the present method is indeed effective to minimize errors associated with the numerical simulations.

  2. abcg2 promoter demethylation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  3. activation promotes tumorigenesis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  4. ash1 promotes amacrine: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  5. activation promotes antithrombotic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  6. activity promotes dna: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  7. aif promotes chromatinolysis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  8. activation promotes myonuclear: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  9. antimitotic chemotherapeutics promote: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  10. actively promotes initiation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  11. activity promotes natural: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  12. ace2 activation promotes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  13. alf promoter activity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  14. activity promotion project: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  15. activator inhibitor-1 promotes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  16. aqueous solution promoted: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Na+ in the aqueous solutions and aromatic rings on the graphite surfaces, promoting the adsorption of water molecules together with cations onto the graphite surfaces, i.e., Na+...

  17. amp phosphodiesterase-4 promotes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    shows the Bode magnitude plots for both VoVi and A (j). The figure shows Leach Jr.,W. Marshall 103 PROMOTION AND TENURE Submission Guidelines Geosciences Websites Summary:...

  18. Demolitions Produce Recyclable Materials for Organization Promoting Economic Activity

    Broader source: Energy.gov [DOE]

    Demolitions have helped generate more than 8 million pounds of metal at the Piketon site for recycling, further promoting economic activity in the region thanks to the American Recovery and...

  19. albicans cdr2 promoter: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 27 Joint Degrees & Promotion towards European Students Computer...

  20. anaphase promoting complex: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 74 Joint Degrees & Promotion towards European Students Computer...

  1. agonist to901317 promotes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 67 Joint Degrees & Promotion towards European Students Computer...

  2. acids promote proliferation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 84 Joint Degrees & Promotion towards European Students Computer...

  3. arsenite promotes centrosome: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 56 Joint Degrees & Promotion towards European Students Computer...

  4. albicans erg11 promoter: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 28 Joint Degrees & Promotion towards European Students Computer...

  5. arachidonic acid promotes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 59 Joint Degrees & Promotion towards European Students Computer...

  6. antibody treatment promotes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 80 Joint Degrees & Promotion towards European Students Computer...

  7. acid promotes detoxification: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 37 Joint Degrees & Promotion towards European Students Computer...

  8. als promote formation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Spinning dark matter halos promote bar formation CERN Preprints Summary: Stellar bars are the most common...

  9. Histone deacetylase inhibitors epigenetically promote reparative events in primary dental pulp cells

    SciTech Connect (OSTI)

    Duncan, Henry F., E-mail: Hal.Duncan@dental.tcd.ie [Division of Restorative Dentistry and Periodontology, Dublin Dental University Hospital, Trinity College Dublin, Lincoln Place, Dublin 2 (Ireland); Smith, Anthony J. [Oral Biology, School of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham (United Kingdom); Fleming, Garry J.P. [Material Science Unit, Division of Oral Biosciences, Dublin Dental University Hospital, Trinity College Dublin, Dublin (Ireland); Cooper, Paul R. [Oral Biology, School of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham (United Kingdom)

    2013-06-10T23:59:59.000Z

    Application of histone deacetylase inhibitors (HDACi) to cells epigenetically alters their chromatin structure and induces transcriptional and cellular reparative events. This study investigated the application of two HDACi, valproic acid (VPA) and trichostatin A (TSA) on the induction of repair-associated responses in primary dental pulp cell (DPC) cultures. Flow cytometry demonstrated that TSA (100 nM, 400 nM) significantly increased cell viability. Neither HDACi was cytotoxic, although cell growth analysis revealed significant anti-proliferative effects at higher concentrations for VPA (>0.5 mM) and TSA (>50 nM). While high-content-analysis demonstrated that HDACi did not significantly induce caspase-3 or p21 activity, p53-expression was increased by VPA (3 mM, 5 mM) at 48 h. HDACi-exposure induced mineralization per cell dose-dependently to a plateau level (VPA-0.125 mM and TSA-25 nM) with accompanying increases in mineralization/dentinogenic-associated gene expression at 5 days (DMP-1, BMP-2/-4, Nestin) and 10 days (DSPP, BMP-2/-4). Both HDACis, at a range of concentrations, significantly stimulated osteopontin and BMP-2 protein expression at 10 and 14 days further supporting the ability of HDACi to promote differentiation. HDACi exert different effects on primary compared with transformed DPCs and promote mineralization and differentiation events without cytotoxic effects. These novel data now highlight the potential in restorative dentistry for applying low concentrations of HDACi in vital pulp treatment. -- Highlights: • Valproic acid and trichostatin A promoted mineralization in primary pulp cells. • Cell viability, apoptosis, caspase-3, p21 unaltered; p53 increased by valproic acid. • Trichostatin A increased cell viability at 24 h at selected concentrations. • Altered cell toxicity and differentiation between primary and transformed cells. • HDACi-induced the differentiation marker proteins osteopontin and BMP-2.

  10. Activation studies with promoted precipitated iron Fischer-Tropsch catalysts

    E-Print Network [OSTI]

    Manne, Rama Krishna

    1991-01-01T23:59:59.000Z

    ACTIVATION STUDIES WITH PROMOTED PRECIPITATED IRON FISCHER ? TROPSCH CATALYSTS A Thesis by RAMA KRISHNA MANNE Submitted to the Oflice of Graduate Studies of Texas A@M University in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE December 1991 Major Subject: Chemical Engineering ACTIVATION STUDIES WITH PROMOTED PRECIPITATED IRON FISCHER ? TROPSCH CATALYSTS A Thesis by RAMA KRISHNA MANNE Approved as to style and content by: Dragomir B. Bukur (Charr...

  11. Policy Strategies and Paths to promote Sustainable Energy Systems - The dynamic Invert Simulation Tool

    E-Print Network [OSTI]

    Stadler, Michael; Kranzl, Lukas; Huber, Claus; Haas, Reinhard; Tsioliaridou, Elena

    2006-01-01T23:59:59.000Z

    Schemes for sustainable energy systems”. InternationalPaths to promote Sustainable Energy Systems - The dynamicmoney - for promoting sustainable energy systems - be spent

  12. Promoting electricity from renewable energy sources -- lessons learned from the EU, U.S. and Japan

    E-Print Network [OSTI]

    Haas, Reinhard

    2008-01-01T23:59:59.000Z

    schemes in the European electricity market. Scheer H. , ThePromoting electricity from renewable energy sources –2001 on the promotion of electricity produced from renewable

  13. New DOE Reports on Smart Grid Technologies Seek to Promote Innovation...

    Office of Environmental Management (EM)

    Reports on Smart Grid Technologies Seek to Promote Innovation, Privacy and Access New DOE Reports on Smart Grid Technologies Seek to Promote Innovation, Privacy and Access October...

  14. Ets factors regulate the polycystic kidney disease-1 promoter

    SciTech Connect (OSTI)

    Puri, Sanjeev [Department of Biochemistry and Molecular Biology, and Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160 (United States); Department of Biochemistry, Panjab University, Chandigarh 160014 (India); Rodova, Marianna [Department of Biochemistry and Molecular Biology, and Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160 (United States); Islam, M. Rafiq [Department of Biochemistry and Molecular Biology, and Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160 (United States); Department of Chemistry/Physics, Northwest Missouri State University, Maryville, MO 64468 (United States); Magenheimer, Brenda S. [Department of Biochemistry and Molecular Biology, and Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160 (United States); Maser, Robin L. [Department of Biochemistry and Molecular Biology, and Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160 (United States); Calvet, James P. [Department of Biochemistry and Molecular Biology, and Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160 (United States)]. E-mail: jcalvet@kumc.edu

    2006-04-21T23:59:59.000Z

    The Ets family of transcription factors consists of a group of highly conserved sequence-specific DNA binding proteins that functionally cooperate with other transcription factors to regulate a number of diverse cellular processes including proliferation, differentiation, and apoptosis. We have analyzed a 3.3 kb 5'-upstream region of the human PKD1 promoter, using transient transfection in HEK293T cells and Drosophila SL2 cells, to demonstrate that the PKD1 promoter is a target of Ets family transcription factors. Our studies showed that PKD1 promoter-luciferase reporter gene expression is downregulated by cotransfected Fli-1 and is upregulated by cotransfected Ets-1. Using deletion constructs, we demonstrated that the sequences responding to Fli-1 and Ets-1 lie within the -200 to +33 bp proximal promoter. This region was found to contain two putative Ets response elements (EREs): an upstream (Ets-A) sequence 5'-CGGAA-3' (-181 to -185) and a downstream (Ets-B) sequence 5'-CGGAT-3' (-129 to -133). Site-directed mutagenesis indicated that both EREs are functional. A Fli-1 DNA binding domain mutant construct (W321R), which is incapable of binding DNA, was unable to inhibit basal promoter activity. In contrast, a Fli-1 DNA binding domain truncation mutant construct, which only contains the DNA binding domain and lacks the transactivation domain, was able to inhibit. These results suggest that the effect of Fli-1 is through direct binding to these EREs. Direct binding of Fli-1 and Ets-1 to the Ets-A and Ets-B sites was supported by electrophoretic mobility shift assays. Lastly, competition between Fli-1 and Ets-1 for the two EREs was demonstrated by showing that increasing amounts of Ets-1 could overcome Fli-1 repression of promoter activity. Taken together, these experiments define the proximal PKD1 promoter region as a potential target of Ets family transcription factors.

  15. Sponsors of CIEEDAC: Environment Canada, Aluminium Association of Canada, Automotive Parts Manufactures' Association, Brewers Association of Canada, Canadian Construction Association, Canadian Energy Pipeline Association,

    E-Print Network [OSTI]

    Sponsors of CIEEDAC: Environment Canada, Aluminium Association of Canada, Automotive Parts Manufactures' Association, Brewers Association of Canada, Canadian Construction Association, Canadian Energy Association of Canada, Chemistry Industry Association of Canada, Forest Products Association of Canada

  16. Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression

    E-Print Network [OSTI]

    a sliding window analysis, we observed that, on average, nucleotide diversity (p) was lowest negative selective pressure on the promoters of kidney transporters. Twenty-one promoters were evaluated pressure than promoters with high activity. Collectively, these results suggest that the proximal promoter

  17. Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

    E-Print Network [OSTI]

    Carvajal-Carmona, Luis G; O’Mara, Tracy A; Painter, Jodie N; Lose, Felicity A; Dennis, Joe; Michailidou, Kyriaki; Tyrer, Jonathan P; Ahmed, Shahana; Ferguson, Kaltin; Healey, Catherine S; Pooley, Karen; Beesley, Jonathan; Cheng, Timothy; Jones, Angela; Howarth, Kimberley; Martin, Lynn; Gorman, Maggie; Hodgson, Shirley; National Study of Endometrial Cancer Genetics Group (NSECG); The Australian National Endometrial Cancer Study Group (ANECS); Wentzensen, Nicholas; Fasching, Peter A; Hein, Alexander; Beckmann, Matthias W; Renner, Stefan P; Dörk, Thilo; Hillemanns, Peter; Dürst, Matthias; Runnebaum, Ingo; Lambrechts, Diether; Coenegrachts, Lieve; Schrauwen, Stefanie; Amant, Frederic; Winterhoff, Boris; Dowdy, Sean C; Goode, Elen L; Teoman, Attila; Salvesen, Helga B; Trovik, Jone; Njolstad, Tormund S; Werner, Henrica MJ; Scott, Rodney J; Ashton, Katie; Proietto, Tony; Otton, Geoffrey; Tzortzatos, Gerasimos; Mints, Miriam; Tham, Emma; RENDOCAS; Hall, Per; Czene, Kamila; Liu, Jianjun; Li, Jingmei; Hopper, John L; Southey, Melissa C; Australian Ovarian Cancer Study (AOCS); Ekici, Arif B; Ruebner, Matthias; Johnson, Nichola; Peto, Julian; Burwinkel, Barbara; Marme, Frederik; Brenner, Hermann; Dieffenbach, Aida K; Meindl, Alfons; Brauch, Hiltrud; The GENICA Network; Lindblom, Annika; Depreeuw, Jeroen; Moisse, Matthieu; Chang-Claude, Jenny; Rudolph, Anja; Couch, Fergus J.; Olson, Janet E; Giles, Graham G; Bruinsma, Fiona; Cunningham, Julie M; Fridley, Brooke L; Børresen-Dale, Anne-Lise; Kristensen, Vessela N; Cox, Angela; Swerdlow, Anthony; Orr, Nicholas; Bolla, Manjeet K; Wang, Qin; Weber, Rachel Palmieri; Chen, Zhihua; Shah, Mitul; Pharoah, Paul D P; Dunning, Alison M; Tomlinson, Ian; Easton, Douglas F; Spurdle, Amanda B; Thompson, Deborah J

    2014-12-09T23:59:59.000Z

    intron 1), and this SNP has been shown to alter TERT pro- moter activity. One of the novel associations (rs13174814) maps to a second region in the TERT promoter and the other (rs62329728) is in the promoter region of CLPTM1L; nei- ther are correlated...

  18. Energy department does about-face: Will promote conservation

    SciTech Connect (OSTI)

    Yates, M.

    1990-03-01T23:59:59.000Z

    This article discusses the Department of Energy's changing policy toward its involvement in conservation and funding of development of renewable energy fuels. Topics include DOE proposals for relighting federal facilities and commercial buildings, promotion of integrated resource planning and demand-side programs, accelerated building guidelines and standards, boosting production efficiency and cutting costs in the manufacture of photovoltaics, cost-competitive ethanol fuels, speed the development of solar detoxification of hazardous wastes out of the laboratory in site-testing programs, improving technologies that convert municipal solid waste into energy, promote the full utilization of all hydropower resources, and fund federal building programs to support photovoltaic and materials sciences research.

  19. Scaffold architecture and fibrin gels promote meniscal cell proliferation

    SciTech Connect (OSTI)

    Pawelec, K. M., E-mail: pawelec.km@gmail.com, E-mail: jw626@cam.ac.uk; Best, S. M.; Cameron, R. E. [Cambridge Centre for Medical Materials, Materials Science and Metallurgy Department, University of Cambridge, Cambridge CB3 0FS (United Kingdom); Wardale, R. J., E-mail: pawelec.km@gmail.com, E-mail: jw626@cam.ac.uk [Division of Trauma and Orthopaedic Surgery, Department of Surgery, University of Cambridge, Cambridge CB2 2QQ (United Kingdom)

    2015-01-01T23:59:59.000Z

    Stability of the knee relies on the meniscus, a complex connective tissue with poor healing ability. Current meniscal tissue engineering is inadequate, as the signals for increasing meniscal cell proliferation have not been established. In this study, collagen scaffold structure, isotropic or aligned, and fibrin gel addition were tested. Metabolic activity was promoted by fibrin addition. Cellular proliferation, however, was significantly increased by both aligned architectures and fibrin addition. None of the constructs impaired collagen type I production or triggered adverse inflammatory responses. It was demonstrated that both fibrin gel addition and optimized scaffold architecture effectively promote meniscal cell proliferation.

  20. Tenure and Promotion Process Proposal Submitted to Faculty Senate by Personnel Policies Committee 4/17/2009 Proposed Tenure and Promotion Process

    E-Print Network [OSTI]

    Gering, Jon C.

    Tenure and Promotion Process Proposal Submitted to Faculty Senate by Personnel Policies Committee 4/17/2009 Proposed Tenure and Promotion Process Preamble: The elements of the tenure and promotion process aim these decisions, the Peer Review Process works in concert with the Administrative Review Process. The Provost

  1. The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity

    SciTech Connect (OSTI)

    Chang, Chung-ke [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China)] [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China); Wu, Tzong-Huah [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China) [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China); Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Institute of Biochemistry, Academia Sinica, Taipei 115, Taiwan (China); Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 300, Taiwan (China); Wu, Chu-Ya [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China) [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China); Graduate Institute of Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan (China); Chiang, Ming-hui; Toh, Elsie Khai-Woon [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China)] [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China); Hsu, Yin-Chih; Lin, Ku-Feng [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China)] [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China); Liao, Yu-heng [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China)] [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China); Huang, Tai-huang, E-mail: bmthh@gate.sinica.edu.tw [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China) [Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan (China); Department of Physics, National Taiwan Normal University, Taipei 106, Taiwan (China); Huang, Joseph Jen-Tse, E-mail: jthuang@chem.sinica.edu.tw [Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan (China)

    2012-08-24T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer The N-terminus of TDP-43 contains an independently folded structural domain (NTD). Black-Right-Pointing-Pointer The structural domains of TDP-43 are arranged in a beads-on-a-string fashion. Black-Right-Pointing-Pointer The NTD promotes TDP-43 oligomerization in a concentration-dependent manner. Black-Right-Pointing-Pointer The NTD may assist nucleic acid-binding activity of TDP-43. -- Abstract: TDP-43 is a DNA/RNA-binding protein associated with different neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-U). Here, the structural and physical properties of the N-terminus on TDP-43 have been carefully characterized through a combination of nuclear magnetic resonance (NMR), circular dichroism (CD) and fluorescence anisotropy studies. We demonstrate for the first time the importance of the N-terminus in promoting TDP-43 oligomerization and enhancing its DNA-binding affinity. An unidentified structural domain in the N-terminus is also disclosed. Our findings provide insights into the N-terminal domain function of TDP-43.

  2. Japan Society for the Promotion of Science (JSPS)

    E-Print Network [OSTI]

    Japan Society for the Promotion of Science (JSPS) Presentation at University College Dublin Time. Emma Sokell, School of Physics) 10:50 Questions and Answers #12;JSPS FELLOWSHIP PROGRAMMES TO JAPAN for excellent researchers to go to Japan to conduct academic collaboration with Japanese researchers. Please

  3. Promoting Sustainable Bioenergy Production and Trade Issue Paper No. 17

    E-Print Network [OSTI]

    Promoting Sustainable Bioenergy Production and Trade Issue Paper No. 17 June 2009 l ICTSD Programme School of Agriculture, Policy and Development University of Reading EU Support for Biofuels and Bioenergy on Agricultural Trade and Sustainable Development By Professor Alan Swinbank School of Agriculture, Policy

  4. Promoting Green Jobs in the Building and Construction Sector

    E-Print Network [OSTI]

    Promoting Green Jobs in the Building and Construction Sector BUILDING FOR ECOLOGICALLY RESPONSIVE Industries" SMX Convention Center, Pasay City CHRISTOPHER CRUZ DE LA CRUZ Philippine Green Building Council 8 the ability of future generations to meet their own needs" #12;· "The fastest growing regional green building

  5. Dynamic social networks promote cooperation in experiments with humans

    E-Print Network [OSTI]

    Rand, David G.

    Dynamic social networks promote cooperation in experiments with humans David G. Randa,b,1 , Samuel and highly organized. Human interactions are not random but rather are structured in social networks. Importantly, ties in these networks often are dynamic, changing in response to the behavior of one's social

  6. The contribution of woodlands to promote sustainable development within the

    E-Print Network [OSTI]

    The contribution of woodlands to promote sustainable development within the regional Structure Plan is a world leader in the research and development of sustainable forestry. Visit us at www development Sustainable development is a popular concept, and was famously articulated in the Brundtland

  7. ARE DEICING SALTS NECESSARY TO PROMOTE SCALING IN CONCRETE?

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    . Keywords: Concrete, cryosuction, durability, frost, poromechanics, porous media, thermo- dynamics, spallingARE DEICING SALTS NECESSARY TO PROMOTE SCALING IN CONCRETE? A. Fabbri1,2 , O. Coussy1 , T. Fen of the different phases that form the porous material. It eventually predicts that a less perme- able sample

  8. Impact of retailer's promotional activities on customer traffic

    E-Print Network [OSTI]

    Tasic, Ivan

    2007-09-17T23:59:59.000Z

    effect on store traffic that is comparable with the customer count effect of an average holiday. Some 55 percent of the positive long-run promotional activity effect is felt immediately, and the remaining 45 percent is spread over a five week long period...

  9. Mining Association Rules in Large Association rules

    E-Print Network [OSTI]

    Terzi, Evimaria

    of other items in the transaction Market-Basket transactions TID Items 1 Bread, Milk 2 Bread, Diaper, Beer, Eggs 3 Milk, Diaper, Beer, Coke 4 Bread, Milk, Diaper, Beer 5 Bread, Milk, Diaper, Coke Examples of association rules {Diaper} {Beer}, {Milk, Bread} {Diaper,Coke}, {Beer, Bread} {Milk}, #12;An even simpler

  10. August 7, 2008 We are pleased to announce the formation of the Southwestern Biofuels Association (SWBA), a

    E-Print Network [OSTI]

    Columbia University

    August 7, 2008 We are pleased to announce the formation of the Southwestern Biofuels Association (SWBA), a progressive trade association promoting the development of renewable biofuels in New, August 15th at noon at the New Mexico Capitol Rotunda in Santa Fe. While energy and biofuels

  11. Clinical Assessment of Percutaneous Radiofrequency Ablation for Painful Metastatic Bone Tumors

    SciTech Connect (OSTI)

    Kojima, Hiroyuki, E-mail: kojimah@takii.kmu.ac.jp; Tanigawa, Noboru; Kariya, Shuji; Komemushi, Atsushi; Shomura, Yuzo; Sawada, Satoshi [Kansai Medical University Takii Hospital, Department of Radiology (Japan)

    2006-12-15T23:59:59.000Z

    Purpose. To investigate the pain-alleviating effects of radiofrequency ablation (RFA) on metastatic bone tumors in relation to tumor size, combined therapy, and percent tumor necrosis rate following RFA. Methods. Subjects comprised 24 patients with 28 painful metastatic bone tumors. A 17G internally cooled electrode was inserted into the tumor for CT guidance and ablation was performed. Bone cement was injected following RFA for 4 tumors involving a weight-bearing bone, while 5 tumors were treated using combined RFA and external irradiation. Percent necrosis rate of the tumor was measured using contrast-enhanced computed tomography 1 week after RFA. Results. Improvement in the visual analog scale (VAS) score was 4.6 {+-} 2.2 for large tumors (>5 cm, n = 12), 3.7 {+-} 1.8 for medium-sized tumors (3.1-5.0 cm, n = 11), and 3.5 {+-} 1.7 for small tumors ({<=}3 cm, n = 4), with no significant differences noted among tumor sizes. Improvement in the VAS score was 3.5 {+-} 1.3 for the 4 tumors in the RFA + bone cement group, 3.2 {+-} 1.9 for the 5 tumors in the RFA + radiation therapy group, and 4.8 {+-} 2.2 for the 18 tumors in the RFA group. No significant differences were identified between groups. The improvement in the VAS score was 3.8 {+-} 2.3, 4.0 {+-} 1.9, and 4.7 {+-} 2.6 in patients with tumor necrosis rates of 0-49%, 50-74%, and 75-100%, respectively. No significant association was observed among these three groups. Conclusion. Percutaneous RFA therapy was effective in relieving pain due to metastatic bone tumors. No relationships appear to exist between initial response and tumor size, combined therapy, and percent tumor necrosis.

  12. Associative list processing unit

    DOE Patents [OSTI]

    Hemmert, Karl Scott; Underwood, Keith D.

    2013-01-29T23:59:59.000Z

    An associative list processing unit and method comprising employing a plurality of prioritized cell blocks and permitting inserts to occur in a single clock cycle if all of the cell blocks are not full. Also, an associative list processing unit and method comprising employing a plurality of prioritized cell blocks and using a tree of prioritized multiplexers descending from the plurality of cell blocks.

  13. WEST TEXAS HISTORICAL ASSOCIATION

    E-Print Network [OSTI]

    Rock, Chris

    WEST TEXAS HISTORICAL ASSOCIATION Public History and Citizen Historians --Guardians of the Hidden Whitfield, Lubbock. Cover: "Stampede," by Tom Lea, El Paso 1940. #12;West Texas Historical Association 91stMurray University, "Black Gold: Larry Gatlin's West Texas Oil Patch Roots" Robert Reitz, Dallas, Texas, "Sputnik

  14. Incentives to Accelerate the Penetration of Electricity in the Industrial Sector by Promoting New Technologies: A French Experiment 

    E-Print Network [OSTI]

    Bouchet, J.; Froehlich, R.

    1983-01-01T23:59:59.000Z

    be effectively associated with them in particular in the form of dual energy installations. EXISTING INCENTIVES Some incentives have been provided by the State, others by E.D.F. State incentives are basically intended to promote energy savings. With a few... Several new approaches designed, tested and imple mented by E.D.F. and its partners, are supported by the Public Authorities. Their aim is to accelerate the design, availability to users and the widespread introduction of elec trical or dual-energy...

  15. Promotional plan: the Center for Urban Horticulture, Seattle, Washington

    E-Print Network [OSTI]

    Pesl, Suzanne R.

    1988-01-01T23:59:59.000Z

    promotional activities enacted by the Center for Urban Horticulture. ACKNOWLEDGMENTS Upon the completion of this phase in my life, there are several people I would like to acknowledge for their support and guidance. First, the Center for Urban... environment for growing a wide range of plants, accessibility of a major research and teaching university (with established Departments of Forestry and Botany), enthusiastic support from local horticultural societies, and instant access to an urban "field...

  16. Switchgrass ubiquitin promoter (PVUBI2) and uses thereof

    DOE Patents [OSTI]

    Stewart, C. Neal; Mann, David George James

    2013-12-10T23:59:59.000Z

    The subject application provides polynucleotides, compositions thereof and methods for regulating gene expression in a plant. Polynucleotides disclosed herein comprise novel sequences for a promoter isolated from Panicum virgatum (switchgrass) that initiates transcription of an operably linked nucleotide sequence. Thus, various embodiments of the invention comprise the nucleotide sequence of SEQ ID NO: 2 or fragments thereof comprising nucleotides 1 to 692 of SEQ ID NO: 2 that are capable of driving the expression of an operably linked nucleic acid sequence.

  17. Promotional effect of CO2 on desulfation processes for pre-sulfated...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Promotional effect of CO2 on desulfation processes for pre-sulfated Pt BaOAl2O3 lean NOx trap catalysts. Promotional effect of CO2 on desulfation processes for pre-sulfated Pt...

  18. Associative list processing unit

    DOE Patents [OSTI]

    Hemmert, Karl Scott; Underwood, Keith D

    2014-04-01T23:59:59.000Z

    An associative list processing unit and method comprising employing a plurality of prioritized cell blocks and permitting inserts to occur in a single clock cycle if all of the cell blocks are not full.

  19. Bachelor of Associate to

    E-Print Network [OSTI]

    Powers, Robert

    Agricultural Economics Agricultural Education Agricultural and Environmental Sciences Communication Agronomy Animal Science * (Biology or Veterinary Science options) Applied Climate Science Applied ScienceBachelor of Science Degree Associate to Bachelor's (AB) Articulation Agreement For more information

  20. Emissions tradeoffs associated with cofiring forest biomass with coal: A case study in Colorado, USA

    E-Print Network [OSTI]

    Fried, Jeremy S.

    , especially in North America and Europe, promote the substitution of forest biomass for fossil fuels to helpEmissions tradeoffs associated with cofiring forest biomass with coal: A case study in Colorado mine and power plant. Model emissions tradeoffs of cofiring forest biomass with coal up to 20% by heat

  1. A cross-sectional assessment of perceptions and promotional demographics of agricultural producers in the Brazos Valley as they pertain to construction goods retailers

    E-Print Network [OSTI]

    Callaway, Cody Douglas

    1993-01-01T23:59:59.000Z

    readership by the agricultural producer D. Examining the potential effectiveness of promotional flyers. The remaining objective, to identify seasonality patterns associated with purchases of construction, fencing, farm, and ranch products for inventory... to carry fencing, farm and ranch products? Please checkM1bstgttulx. Weedsen's Furrow's Producer's hicCey's Farm fe Braces Coup Ranch Valley Lumber Still another multiple category question, question thirteen was presented as follows. Radic Flyers...

  2. Department of Energy Announces $15 Million to Promote Innovative...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    environmental risk factors associated with geothermal heat recovery such as water consumption and induced seismicity. Cooperation and innovative partnerships among geothermal,...

  3. Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1? pathway

    SciTech Connect (OSTI)

    Zheng, Xuqin [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210029 (China)] [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210029 (China); Sun, Tao [Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu Province 210002 (China)] [Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu Province 210002 (China); Wang, Xiaodong, E-mail: xdwang666@hotmail.com [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210029 (China)] [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210029 (China)

    2013-07-05T23:59:59.000Z

    Highlights: •TC, a CB2R specific agonist, stimulates SIRT1 activity by PKA/CREB pathway. •TC promotes PGC-1? transcriptional activity by increasing its deacetylation. •TC increases the expression of genes linked to FAO and promotes the rate of FAO. •The effects of TC in FAO are dependent on CB2R. •Suggesting CB2R as a target to treat diseases with lipid dysregulation. -- Abstract: Abnormal fatty acid oxidation has been associated with obesity and type 2 diabetes. At the transcriptional level, peroxisome proliferator-activated receptor-gamma coactivator 1? (PGC-1?) has been reported to strongly increase the ability of hormone nuclear receptors PPAR? and ERR? to drive transcription of fatty acid oxidation enzymes. In this study, we report that a specific agonist of the type 2 cannabinoid receptor (CB2R) can lead to fatty acid oxidation through the PGC-1? pathway. We have found that CB2R is expressed in differentiated C2C12 myotubes, and that use of the specific agonist trans-caryophyllene (TC) stimulates sirtuin 1 (SIRT1) deacetylase activity by increasing the phosphorylation of cAMP response element-binding protein (CREB), thus leading to increased levels of PGC-1? deacetylation. This use of TC treatment increases the expression of genes linked to the fatty acid oxidation pathway in a SIRT1/PGC-1?-dependent mechanism and also drastically accelerates the rate of complete fatty acid oxidation in C2C12 myotubes, neither of which occur when CB2R mRNA is knocked down using siRNA. These results reveal that activation of CB2R by a selective agonist promotes lipid oxidation through a signaling/transcriptional pathway. Our findings imply that pharmacological manipulation of CB2R may provide therapeutic possibilities to treat metabolic diseases associated with lipid dysregulation.

  4. The Role of Peer Support for Girls and Women in the STEM Pipeline: Promoting Identification with STEM and Mitigating the Negative Effects of Sexism

    E-Print Network [OSTI]

    Robnett, Rachael

    2013-01-01T23:59:59.000Z

    AND WOMEN IN THE STEM PIPELINE: PROMOTING IDENTIFICATIONand Women in the STEM Pipeline: Promoting Identificationand Women in the STEM Pipeline: Promoting Identification

  5. Promotion of Wind Energy: Lessons Learned from International Experience and

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation,Pillar Group BV Jump to:Information Promoting Clean Cars: Case Study ofUnited

  6. Promoting Sustainability on a Global Scale | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreakingMay 2015 < prev next >PresentationsNowPromoting Sustainability on a

  7. Nepali Alternative Energy Promotion Centre (AEPC) | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLuOpen EnergyNelsoniX Ltd JumpNepali Alternative Energy Promotion

  8. Correlations between promoter activity and its nucleotide positions in spacing region

    E-Print Network [OSTI]

    Li, Jingwei

    2015-01-01T23:59:59.000Z

    Transcription is one of the essential processes for cells to read genetic information encoded in genes, which is initiated by the binding of RNA polymerase to related promoter. Experiments have found that the nucleotide sequence of promoter has great influence on gene expression strength, or promoter activity. In synthetic biology, one interesting question is how we can synthesize a promoter with given activity, and which positions of promoter sequence are important for determining its activity. In this study, based on recent experimental data, correlations between promoter activity and its sequence positions are analyzed by various methods. Our results show that, except nucleotides in the two highly conserved regions, $-35$ box and $-10$ box, influences of nucleotides in other positions are also not neglectable. For example, modifications of nucleotides around position $-19$ in spacing region may change promoter activity in a large scale. The results of this study might be helpful to our understanding of bio...

  9. HEALTH CARE ASSOCIATION

    E-Print Network [OSTI]

    Leistikow, Bruce N.

    HEALTH CARE COMPLIANCE ASSOCIATION 5780 Lincoln Drive · Suite 120 · Minneapolis, MN 55436 · 888 of the following document, "Evaluating and Improving a Compliance Program, A Resource for Health care Board Members, Health care Executives and Compliance Officers." This resource is now available to all HCCA members

  10. C. Beckermann Associate Professor.

    E-Print Network [OSTI]

    Beckermann, Christoph

    losses in the depth direction is also discussed. The importance of accurate thermophysicalproperties. It was found that a model based on a smooth channel with uniform wall heat Contributed by the Electrical by the EEPD June 1, 1993; revised manuscript received January 4, 1994. Associate Technical Editor: W. Z. Black

  11. 1 Outreach, Education and Domestic Market Enhancement 2 Export Promotion and Assistance

    SciTech Connect (OSTI)

    Geothermal Energy Association

    2004-03-15T23:59:59.000Z

    Geothermal Energy Association supports the US geothermal industry in its efforts to bring more clean geothermal energy on-line throughout the world. Activities designed to accomplish this goal include: (1) developing and maintaining data bases, web pages, (2) commissioning of special studies and reports, (3) preparing, printing and distributing brochures and newsletters, (4) developing exhibits and displays, and participating in trade shows, (5) designing, producing and disseminating audio-video materials, (6) monitoring and coordinating programs carried out by US DOE and other Federal agencies, (7) holding workshops to facilitate communication between researchers and industry and to encourage their recognition of emerging markets for geothermal technology, (8) attending conferences, making speeches and presentation, and otherwise interacting with environmental and other renewable energy organizations and coalitions, (9) hosting events in Washington, DC and other appropriate locations to educate Federal, State and local representatives, environmental groups, the news media, and other about the status and potential of geothermal energy, (10) conducting member services such as the preparation and distribution of a member newsletter related to operating and maintaining s useful and viable association, and (11) performing similar kinds of activities designed to inform others about geothermal energy. The activities of the export promotion aim to assist industry in accomplishing the goal of successfully penetrating and developing energy in country with existing geothermal resources and a desire to develop them. Activities including in export promotion are: (1)needs analysis and assessment involve monitoring the progress of developing markets and projects overseas and working with US industry to determine what future activities by GEA would be of greatest assistance, (2) outreach includes the preparation and dissemination of brochures and videos for foreign professionals, officials and decision-makers as well as presentations of information of the geothermal technology and the capabilities of the US geothermal industry, (3) Market conditioning involves first, evaluating the market and challenges for conducting business successfully in a country followed by appropriate training or technical assistance, (4) Market developing includes activities conducted to assist industry in developing the market for sales of services and technology, including direct and reverse trade missions, support for industry to participate in conferences overseas to sell goods and services, and other activities.

  12. actin cag promoter: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Stewart; Ii Thomas; P. Stossel; David J. Kwiatkowski; John H. Hartwig 1990-01-01 17 Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating...

  13. Influence of Radiofrequency Ablation of Lung Cancer on Pulmonary Function

    SciTech Connect (OSTI)

    Tada, Akihiro, E-mail: tdakihiro@gmail.com; Hiraki, Takao [Okayama University Medical School, Department of Radiology (Japan); Iguchi, Toshihiro [Fukuyama City Hospital, Department of Radiology (Japan); Gobara, Hideo; Mimura, Hidefumi [Okayama University Medical School, Department of Radiology (Japan); Toyooka, Shinichi [Okayama University Medical School, Department of Cancer and Thoracic Surgery (Japan); Kiura, Katsuyuki [Okayama University Medical School, Department of Respiratory Medicine (Japan); Tsuda, Toshihide [Okayama University Graduate School, Department of Environmental Epidemiology, Graduate School of Environmental Science (Japan); Mitsuhashi, Toshiharu [Okayama University Medical School, Department of Epidemiology (Japan); Kanazawa, Susumu [Okayama University Medical School, Department of Radiology (Japan)

    2012-08-15T23:59:59.000Z

    Purpose: The purpose of this study was to evaluate altered pulmonary function retrospectively after RFA. Methods: This retrospective study comprised 41 ablation sessions for 39 patients (22 men and 17 women; mean age, 64.8 years). Vital capacity (VC) and forced expiratory volume in 1 s (FEV{sub 1}) at 1 and 3 months after RFA were compared with the baseline (i.e., values before RFA). To evaluate the factors that influenced impaired pulmonary function, univariate analysis was performed by using multiple variables. If two or more variables were indicated as statistically significant by univariate analysis, these variables were subjected to multivariate analysis to identify independent factors. Results: The mean VC and FEV{sub 1} before RFA and 1 and 3 months after RFA were 3.04 and 2.24 l, 2.79 and 2.11 l, and 2.85 and 2.13 l, respectively. The values at 1 and 3 months were significantly lower than the baseline. Severe pleuritis after RFA was identified as the independent factor influencing impaired VC at 1 month (P = 0.003). For impaired FEV{sub 1} at 1 month, only severe pleuritis (P = 0.01) was statistically significant by univariate analysis. At 3 months, severe pleuritis (VC, P = 0.019; FEV{sub 1}, P = 0.003) and an ablated parenchymal volume {>=}20 cm{sup 3} (VC, P = 0.047; FEV{sub 1}, P = 0.038) were independent factors for impaired VC and FEV{sub 1}. Conclusions: Pulmonary function decreased after RFA. RFA-induced severe pleuritis and ablation of a large volume of marginal parenchyma were associated with impaired pulmonary function.

  14. Promote cooperation by localised small-world communication

    E-Print Network [OSTI]

    Zi-Gang Huang; Sheng-Jun Wang; Xin-Jian Xu; Ying-Hai Wang

    2008-01-15T23:59:59.000Z

    The emergence and maintenance of cooperation within sizable groups of unrelated humans offer many challenges for our understanding. We propose that the humans' capacity of communication, such as how many and how far away the fellows can build up mutual communications, may affect the evolution of cooperation. We study this issue by means of the public goods game (PGG) with a two-layered network of contacts. Players obtain payoffs from five-person public goods interactions on a square lattice (the interaction layer). Also, they update strategies after communicating with neighbours in learning layer, where two players build up mutual communication with a power law probability depending on their spatial distance. Our simulation results indicate that the evolution of cooperation is indeed sensitive to how players choose others to communicate with, including the amount as well as the locations. The tendency of localised communication is proved to be a new mechanism to promote cooperation.

  15. Process studies with a promoted transition metal-zeolite catalyst

    SciTech Connect (OSTI)

    Pennline, H.W.; Gormley, R.J.; Schehl, R.R.

    1984-09-01T23:59:59.000Z

    The conversion of synthesis gas to gasoline-range hydrocarbons was investigated with a cobalt-thoria-zeolite catalyst. The coprecipitated transition metal and promoter were intimately mixed with ZSM-5 zeolite and then extruded with an alumina binder. Tests were conducted in a gradientless reactor, where initial results of high yields of gasoline-range hydrocarbons with a low ratio synthesis gas led to an extensive study of the catalyst. The effects of support, temperature (220-320C), pressure (1.14-2.17 MPa), and feed gas composition (1H2/1CO-3H2/1CO) on catalyst activity, stability, and product selectivity are discussed. Analyses of the deactivated bifunctional catalyst are also reported.

  16. Chemical inducible promoter used to obtain transgenic plants with a silent marker

    DOE Patents [OSTI]

    Aoyama, Takashi; Zuo, Jianru; Chua, Nam-Hai

    2004-08-31T23:59:59.000Z

    A chemically inducible promoter is described that may be used to transform plants, including tobacco and lettuce, with genes which are easily regulatable by adding the plants or plant cells to a medium containing an inducer of the promoter or by removing the plants or plant cells from such medium. The promoter described is one that is inducible by a glucocorticoid which is not endogenous to plants. Such promoters may be used with a variety of genes such as ipt or knotted1 to induce shoot formation in the presence of a glucocorticoid. The promoter may also be used with antibiotic or herbicide resistance genes which are then regulatable by the presence or absence of inducer rather than being constitutive. Other examples of genes which may be placed under the control of the inducible promoter are also presented.

  17. TGF-?/HA complex promotes tympanic membrane keratinocyte migration and proliferation via ErbB1 receptor

    SciTech Connect (OSTI)

    Mei Teh, Bing, E-mail: bing.teh@earscience.org.au [Ear Sciences Centre, School of Surgery, The University of Western Australia, Nedlands, WA (Australia); Ear Science Institute Australia, Subiaco, WA (Australia); Department of Otolaryngology, Head, Neck and Skull Base Surgery, Sir Charles Gairdner Hospital, Nedlands, WA (Australia); Redmond, Sharon L. [Ear Sciences Centre, School of Surgery, The University of Western Australia, Nedlands, WA (Australia); Ear Science Institute Australia, Subiaco, WA (Australia); Shen, Yi [Ear Sciences Centre, School of Surgery, The University of Western Australia, Nedlands, WA (Australia); Ear Science Institute Australia, Subiaco, WA (Australia); Department of Otolaryngology, Head and Neck, Ningbo Lihuili Hospital (Ningbo Medical Centre), Ningbo, Zhejiang (China); Atlas, Marcus D. [Ear Sciences Centre, School of Surgery, The University of Western Australia, Nedlands, WA (Australia); Ear Science Institute Australia, Subiaco, WA (Australia); Department of Otolaryngology, Head, Neck and Skull Base Surgery, Sir Charles Gairdner Hospital, Nedlands, WA (Australia); Marano, Robert J.; Dilley, Rodney J. [Ear Sciences Centre, School of Surgery, The University of Western Australia, Nedlands, WA (Australia); Ear Science Institute Australia, Subiaco, WA (Australia)

    2013-04-01T23:59:59.000Z

    Tympanic membrane perforations are common and represent a management challenge to clinicians. Current treatments for chronic perforations involve a graft surgery and require general anaesthesia, including associated costs and morbidities. Bioactive molecules (e.g. growth factors, cytokines) play an important role in promoting TM wound healing following perforation and the use of growth factors as a topical treatment for tympanic membrane perforations has been suggested as an alternative to surgery. However, the choice of bioactive molecules best suited to promote wound healing has yet to be identified. We investigated the effects of hyaluronic acid, vitronectin, TGF-?, IL-24 and their combinations on migration, proliferation and adhesion of cultured human tympanic membrane-derived keratinocytes (hTM), in addition to their possible mechanisms of action. We found that TGF-?, TGF-?/HA and TGF-?/IL-24 promoted wound healing by significantly increasing both migration and proliferation. TGF-? and/or HA treated cells showed comparable cell–cell adhesion whilst maintaining an epithelial cell phenotype. With the use of receptor binding inhibitors for ErbB1 (AG1478) and CD44 (BRIC235), we revealed that the activation of ErbB1 is required for TGF-?/HA-mediated migration and proliferation. These results suggest factors that may be incorporated into a tissue-engineered membrane or directly as topical treatment for tympanic membrane perforations and hence reduce the need for a surgery. - Highlights: ? TGF-?, TGF-?/HA and TGF-?/IL-24 improved hTM keratinocyte migration and proliferation. ? TGF-? and/or HA maintained epithelial cell phenotype. ? TGF-?/HA-mediated migration and proliferation requires activation of ErbB1 receptor.

  18. Designing PV Incentive Programs to Promote System Performance: A Review of Current Practice

    E-Print Network [OSTI]

    Barbose, Galen; Wiser, Ryan; Bolinger, Mark

    2006-01-01T23:59:59.000Z

    Dan. 2006. Best Practices in PV Rebate Programs: Helpingprogram staff. Designing PV Incentive Programs to PromoteGroup), Mike Taylor Designing PV Incentive Programs to

  19. Designing PV Incentive Programs to Promote Performance: A Review of Current Practice

    E-Print Network [OSTI]

    Barbose, Galen; Wiser, Ryan; Bolinger, Mark

    2007-01-01T23:59:59.000Z

    DESIGNING PV INCENTIVE PROGRAMS TO PROMOTE SYSTEMcustomer-sited photovoltaic (PV) systems, provided throughface to ensuring that their PV systems perform well, and the

  20. BIRC6 promotes hepatocellular carcinogenesis: Interaction of BIRC6 with p53 facilitating p53 degradation

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    that BIRC6 could regulate the degradation of p53 rather thanp53 and facilitated its degradation by ubiquitination incantly promoted the degradation of p53 by ubiquitination (

  1. Processes and palladium-promoted catalysts for conducting Fischer-Tropsch synthesis

    DOE Patents [OSTI]

    Singleton, Alan H. (Baden, PA); Oukaci, Rachid (Gibsonia, PA); Goodwin, James G. (Cranberry Township, PA)

    2000-01-01T23:59:59.000Z

    A process for hydrocarbon synthesis comprising the step of reacting a synthesis gas in the presence of a cobalt catalyst promoted with palladium.

  2. Hydrogel surfaces to promote attachment and spreading of endothelial progenitor cells

    E-Print Network [OSTI]

    Camci-Unal, Gulden

    Endothelialization of artificial vascular grafts is a challenging process in cardiovascular tissue engineering. Functionalized biomaterials could be promising candidates to promote endothelialization in repair of cardiovascular ...

  3. Quasar-galaxy associations

    E-Print Network [OSTI]

    P. A. Thomas; R. L. Webster; M. J. Drinkwater

    1994-08-29T23:59:59.000Z

    There is controversy about the measurement of statistical associations between bright quasars and faint, presumably foreground galaxies. We look at the distribution of galaxies around an unbiased sample of 63 bright, moderate redshift quasars using a new statistic based on the separation of the quasar and its nearest neighbour galaxy. We find a significant excess of close neighbours at separations less than about 10 arcsec which we attribute to the magnification by gravitational lensing of quasars which would otherwise be too faint to be included in our sample. About one quarter to one third of the quasars are so affected although the allowed error in this fraction is large.

  4. Faculty Tenure and Promotion, 2008 Nine ETSU College of Arts and Sciences faculty members were promoted and six were granted tenure by the

    E-Print Network [OSTI]

    Karsai, Istvan

    Faculty Tenure and Promotion, 2008 Nine ETSU College of Arts and Sciences faculty members were in 90 of Tennessee's 95 counties. The following ETSU faculty members attained the rank of full professor

  5. American University of Beirut Faculty Promotions 2012-2013

    E-Print Network [OSTI]

    Shihadeh, Alan

    literature written in English. Her book, "Post- War Anglophone Lebanese Fiction: Home Matters in the Diaspora, and (II) understand membrane properties, protein- ligandinteraction, and photo-physical behavior Ruble, Associate Professor, Department of Economics Dr. Ruble's research field is energy economics

  6. International District Energy Association

    Broader source: Energy.gov [DOE]

    Since its formation in 1909, the International District Energy Association (IDEA) has served as a principal industry advocate and management resource for owners, operators, developers, and suppliers of district heating and cooling systems in cities, campuses, bases, and healthcare facilities. Today, with over 1,400 members in 26 countries, IDEA continues to organize high-quality technical conferences that inform, connect, and advance the industry toward higher energy efficiency and lower carbon emissions through innovation and investment in scalable sustainable solutions. With the support of DOE, IDEA performs industry research and market analysis to foster high impact projects and help transform the U.S. energy industry. IDEA was an active participant in the original Vision and Roadmap process and has continued to partner with DOE on combined heat and power (CHP) efforts across the country.

  7. PROMOTED ZINC CHROMITE CATALYSTS FOR HIGHER ALCOHOL SYNTHESIS

    SciTech Connect (OSTI)

    Ms. Xiaolei Sun; Professor George W. Roberts

    2000-08-29T23:59:59.000Z

    During this reporting period, a ''zinc chromite'' catalyst promoted with 6 wt.% cesium (Cs) was evaluated at the following conditions: Temperature--375 C; Total Pressure--6.8 MPa (1000 psig); Gas Hourly Space Velocity (GHSV) - 5000 standard liters/kg(cat)-hr, and; H{sub 2}/CO feed ratio--1.0 mole/mole. Decahydronaphthalene (DHN) was used as the slurry liquid. The experiment lasted for eight days of continuous operation. Although the experimental data once again did not exhibit the desired degree of consistency, the data did show that methanol was the primary reaction product. The slurry liquid did not decompose or alkylate to a measurable extent during the continuous 8-day experiment. There was a relatively significant loss of catalyst surface area during the experiment. Gas chromatography/mass spectrometry (GC/MS) analysis of various fractions of ''spent'' THQ was carried out. The fractions were prepared by silica gel liquid chromatography (LC). Chemical formuli and probable structures for each major compound were obtained. However, a higher degree of purification will be necessary to allow nuclear magnetic resonance (NMR) analysis to be used for definitive compound identification. A new Maxpro gas booster (DLE 15-75) was purchased because the existing Haskel gas booster once again developed a severe leak of carbon monoxide and hydrogen, and was judged to be unworthy of repair.

  8. Evaluating Government's Policies on Promoting Smart Metering Diffusion in Retail Electricity Markets via

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    Evaluating Government's Policies on Promoting Smart Metering Diffusion in Retail Electricity on promoting smart metering in the U.K. retail electricity market. We break down the policy into four possible recommendations for the energy mar- ket is the adoption of smart metering technology, which, in addition

  9. Preservation, Innovation and Promotion of ethnic arts and crafts Prepared by

    E-Print Network [OSTI]

    Mlllet, Dylan B.

    The team of Dharohar has a diverse knowledge of management, engineering and entrepreneurship. OneDharohar Preservation, Innovation and Promotion of ethnic arts and crafts Prepared by Sweta None. Unfortunately this rich tapestry has been losing its significance. It can only be preserved and promoted

  10. Policy and institutional frameworks for the promotion of sustainable biofuels in Mali

    E-Print Network [OSTI]

    Mound, Jon

    1 Policy and institutional frameworks for the promotion of sustainable biofuels in Mali Nicola. #12;3 Policy and institutional frameworks for the promotion of sustainable biofuels in Mali © Nicola and inter-policy coherence.......................................23 3.2.2 Targets for Jatropha-based biofuel

  11. Policy and institutional frameworks for the promotion of sustainable biofuels in Mali

    E-Print Network [OSTI]

    Mound, Jon

    1 Policy and institutional frameworks for the promotion of sustainable biofuels in Mali Nicola;3 Policy and institutional frameworks for the promotion of sustainable biofuels in Mali © Nicola Favretto and inter-policy coherence.......................................23 3.2.2 Targets for Jatropha-based biofuel

  12. Technology in Motion Vehicle (TMV) To promote truck and bus safety programs and

    E-Print Network [OSTI]

    Technology in Motion Vehicle (TMV) Goal To promote truck and bus safety programs and technologies messages at multiple venues Demonstrate proven and emerging safety technologies to state and motor carrier stakeholders Promote deployment of safety technologies by fleets and state MCSAP agencies Evaluate program

  13. Comparing the use of Social Networking and Traditional Media Channels for Promoting Citizen Science

    E-Print Network [OSTI]

    Hearst, Marti

    Comparing the use of Social Networking and Traditional Media Channels for Promoting Citizen Science This paper examines how social networks can be used to recruit and promote a crowdsourced citizen science releases, news stories, and participation campaigns. The target studied is Creek Watch, a citizen science

  14. Encapsulant materials and associated devices

    DOE Patents [OSTI]

    Kempe, Michael D (Littleton, CO); Thapa, Prem (Lima, OH)

    2011-03-08T23:59:59.000Z

    Compositions suitable for use as encapsulants are described. The inventive compositions include a high molecular weight polymeric material, a curing agent, an inorganic compound, and a coupling agent. Optional elements include adhesion promoting agents, colorants, antioxidants, and UV absorbers. The compositions have desirable diffusivity properties, making them suitable for use in devices in which a substantial blocking of moisture ingress is desired, such as photovoltaic (PV) modules.

  15. Encapsulant materials and associated devices

    DOE Patents [OSTI]

    Kempe, Michael D (Littleton, CO); Thapa, Prem (Lima, OH)

    2012-05-22T23:59:59.000Z

    Compositions suitable for use as encapsulants are described. The inventive compositions include a high molecular weight polymeric material, a curing agent, an inorganic compound, and a coupling agent. Optional elements include adhesion promoting agents, colorants, antioxidants, and UV absorbers. The compositions have desirable diffusivity properties, making them suitable for use in devices in which a substantial blocking of moisture ingress is desired, such as photovoltaic (PV) modules.

  16. Promoting system-level learning from project-level lessons

    SciTech Connect (OSTI)

    Jong, Amos A. de, E-mail: amosdejong@gmail.com [Innovation Management, Utrecht (Netherlands); Runhaar, Hens A.C., E-mail: h.a.c.runhaar@uu.nl [Section of Environmental Governance, Utrecht University, Utrecht (Netherlands); Runhaar, Piety R., E-mail: piety.runhaar@wur.nl [Organisational Psychology and Human Resource Development, University of Twente, Enschede (Netherlands); Kolhoff, Arend J., E-mail: Akolhoff@eia.nl [The Netherlands Commission for Environmental Assessment, Utrecht (Netherlands); Driessen, Peter P.J., E-mail: p.driessen@geo.uu.nl [Department of Innovation and Environment Sciences, Utrecht University, Utrecht (Netherlands)

    2012-02-15T23:59:59.000Z

    A growing number of low and middle income nations (LMCs) have adopted some sort of system for environmental impact assessment (EIA). However, generally many of these EIA systems are characterised by a low performance in terms of timely information dissemination, monitoring and enforcement after licencing. Donor actors (such as the World Bank) have attempted to contribute to a higher performance of EIA systems in LMCs by intervening at two levels: the project level (e.g. by providing scoping advice or EIS quality review) and the system level (e.g. by advising on EIA legislation or by capacity building). The aims of these interventions are environmental protection in concrete cases and enforcing the institutionalisation of environmental protection, respectively. Learning by actors involved is an important condition for realising these aims. A relatively underexplored form of learning concerns learning at EIA system-level via project level donor interventions. This 'indirect' learning potentially results in system changes that better fit the specific context(s) and hence contribute to higher performances. Our exploratory research in Ghana and the Maldives shows that thus far, 'indirect' learning only occurs incidentally and that donors play a modest role in promoting it. Barriers to indirect learning are related to the institutional context rather than to individual characteristics. Moreover, 'indirect' learning seems to flourish best in large projects where donors achieved a position of influence that they can use to evoke reflection upon system malfunctions. In order to enhance learning at all levels donors should thereby present the outcomes of the intervention elaborately (i.e. discuss the outcomes with a large audience), include practical suggestions about post-EIS activities such as monitoring procedures and enforcement options and stimulate the use of their advisory reports to generate organisational memory and ensure a better information dissemination.

  17. GENETIC MODIFICATION OF GIBBERELLIC ACID SIGNALING TO PROMOTE CARBON SEQUESTRATION IN TREE ROOTS AND STEMS

    SciTech Connect (OSTI)

    Busov, Victor

    2013-03-05T23:59:59.000Z

    Semidwarfism has been used extensively in row crops and horticulture to promote yield, reduce lodging, and improve harvest index, and it might have similar benefits for trees for short-rotation forestry or energy plantations, reclamation, phytoremediation, or other applications. We studied the effects of the dominant semidwarfism transgenes GA Insensitive (GAI) and Repressor of GAI-Like, which affect gibberellin (GA) action, and the GA catabolic gene, GA 2-oxidase, in nursery beds and in 2-year-old high-density stands of hybrid poplar (Populus tremula ? Populus alba). Twenty-nine traits were analyzed, including measures of growth, morphology, and physiology. Endogenous GA levels were modified in most transgenic events; GA(20) and GA(8), in particular, had strong inverse associations with tree height. Nearly all measured traits varied significantly among genotypes, and several traits interacted with planting density, including aboveground biomass, root-shoot ratio, root fraction, branch angle, and crown depth. Semidwarfism promoted biomass allocation to roots over shoots and substantially increased rooting efficiency with most genes tested. The increased root proportion and increased leaf chlorophyll levels were associated with changes in leaf carbon isotope discrimination, indicating altered water use efficiency. Semidwarf trees had dramatically reduced growth when in direct competition with wild-type trees, supporting the hypothesis that semidwarfism genes could be effective tools to mitigate the spread of exotic, hybrid, and transgenic plants in wild and feral populations. We modified gibberellin (GA) metabolism and signaling in transgenic poplars using dominant transgenes and studied their effects for 3 years under field conditions. The transgenes that we employed either reduced the bioactive GAs, or attenuated their signaling. The majority of transgenic trees had significant and in many cases dramatic changes in height, crown architecture, foliage morphology, flowering onset, floral structure, and vegetative phenology. Most transgenes elicited various levels of height reduction consistent with the roles of GA in elongation growth. Several other growth traits were proportionally reduced, including branch length, internode distance, and leaf length. In contrast to elongation growth, stem diameter growth was much less affected, suggesting that semi-dwarf trees in dense stands might provide high levels of biomass production and carbon sequestration. The severity of phenotypic effects was strongly correlated with transgene expression among independent transgenic events, but often in a non-linear manner, the form of which varied widely among constructs. The majority of semi-dwarfed, transgenic plants showed delayed bud flush and early bud set, and expression of a native GAI transgene accelerated first time flowering in the field. All of the phenotypic changes observed in multiple years were stable over the 3 years of field study. Our results suggest that transgenic modification of GA action may be useful for producing semi-dwarf trees with modified growth and morphology for horticulture and other uses. We studied the poplar C(19) gibberellin 2-oxidase (GA2ox) gene subfamily. We show that a set of paralogous gene pairs differentially regulate shoot and root development. ? PtGA2ox4 and its paralogous gene PtGA2ox5 are primarily expressed in aerial organs, and overexpression of PtGA2ox5 produced a strong dwarfing phenotype characteristic of GA deficiency. Suppression of PtGA2ox4 and PtGA2ox5 led to increased biomass growth, but had no effect on root development. By contrast, the PtGA2ox2 and PtGA2ox7 paralogous pair was predominantly expressed in roots, and when these two genes were RNAi-suppressed it led to a decrease of root biomass. ? The morphological changes in the transgenic plants were underpinned by tissue-specific increases in bioactive GAs that corresponded to the predominant native expression of the targeted paralogous gene pair. Although RNAi suppression of both paralogous pairs led to changes in wood developmen

  18. Associated particle imaging (API)

    SciTech Connect (OSTI)

    NONE

    1998-05-01T23:59:59.000Z

    Associated Particle Imaging (API) is an active neutron probe technique that provides a 3-D image with elemental composition of the material under interrogation, and so occupies a unique niche in the interrogation of unknown objects. The highly penetrating nature of neutrons enables API to provide detailed information about targets of interest that are hidden from view. Due to the isotropic nature of the induced reactions, radiation detectors can be set on the same side of the object as the neutron source, so that the object can be interrogated from a single side. At the heat of the system is a small generator that produces a continuous, monoenergetic flux of neutrons. By measuring the trajectory of coincident alpha particles that are produced as part of the process, the trajectory of the neutron can be inferred. Interactions between a neutron and the material in its path often produce a gamma ray whose energy is characteristic of that material. When the gamma ray is detected, its energy is measured and combined with the trajectory information to produce a 3-D image of the composition of the object being interrogated. During the course of API development, a number of improvements have been made. A new, more rugged sealed Tube Neutron Generator (STNG) has been designed and fabricated that is less susceptible to radiation damage and better able to withstand the rigors of fielding than earlier designs. A specialized high-voltage power supply for the STNG has also been designed and built. A complete package of software has been written for the tasks of system calibration, diagnostics and data acquisition and analysis. A portable system has been built and field tested, proving that API can be taken out of the lab and into real-world situations, and that its performance in the field is equal to that in the lab.

  19. Solvent-Driven Preferential Association of Lignin with Regions of Crystalline Cellulose in Molecular Dynamics Simulation

    SciTech Connect (OSTI)

    Lindner, Benjamin [ORNL] [ORNL; Petridis, Loukas [ORNL] [ORNL; Schulz, Roland [ORNL] [ORNL; Smith, Jeremy C [ORNL] [ORNL

    2013-01-01T23:59:59.000Z

    The precipitation of lignin onto cellulose after pretreatment of lignocellulosic biomass is an obstacle to economically viable cellulosic ethanol production. Here, 750 ns nonequilibrium molecular dynamics simulations are reported of a system of lignin and cellulose in aqueous solution. Lignin is found to strongly associate with itself and the cellulose. However, noncrystalline regions of cellulose are observed to have a lower tendency to associate with lignin than crystalline regions, and this is found to arise from stronger hydration of the noncrystalline chains. The results suggest that the recalcitrance of crystalline cellulose to hydrolysis arises not only from the inaccessibility of inner fibers but also due to the promotion of lignin adhesion.

  20. activation promotes anti-thrombotic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  1. anti-tumor promoting activity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  2. acid promotes epithelial-to-mesenchymal-like: Topics by E-print...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  3. activity coal-derived promoted: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  4. alpha-glucosidase promotes hemozoin: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    help this work. With the growing rate of obesity, the high cost of gas and climate change, we must rethink and reshape our transportation systems and networks to promote active...

  5. An Economic Evaluation of the Hass Avocado Promotion Order’s First Five Years

    E-Print Network [OSTI]

    Carman, Hoy; Li, Lan; Sexton, Richard J.

    2009-01-01T23:59:59.000Z

    An Economic Evaluation of the Hass Avocado Promotion Order’s19 ii An Economic Evaluation of the Hass Avocado Promotionand R.K. Craft. An Economic Evaluation of California Avocado

  6. antioxidants prevent health-promoting: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    PROMOTION AMONG RACIAL AND ETHNIC MINORITY MALES Funding Opportunity Number: PA-10-236. CFDA Number(s): 93.361, 93.847, 93.837, 93.399. Engineering Websites Summary: initial and...

  7. A cost benefit analysis of employee assistance programs and health promotion programs

    E-Print Network [OSTI]

    Sykora, Ellen M

    2013-02-22T23:59:59.000Z

    For many years business has been searching for ways to make companies more profitable. Some programs that many businesses have implemented in order to increase profits are Employee Assistance Programs (EAPs) and Health Promotion Programs (HPPs...

  8. DOE Project Leads to New Alliance to Promote Low-Impact Drilling

    Broader source: Energy.gov [DOE]

    A project supported by the Office of Fossil Energy's National Energy Technology Laboratory (NETL) has given rise to a major new research consortium to promote advanced technology for low-impact oil and gas drilling.

  9. NREL Materials Recycling Procedure Purpose To promote environmental sustainability and stewardship, NREL provides the

    E-Print Network [OSTI]

    NREL Materials Recycling Procedure Purpose To promote environmental sustainability and stewardship, NREL provides the infrastructure for workers to incorporate materials recycling in daily operations. This procedure identifies appropriate materials, collection locations, and rules and processes for recycling

  10. anti-dsdna antibodies promote: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 53 Joint Degrees & Promotion towards European Students Computer...

  11. autonomy-based bioethics promote: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    within bacteria in order to fine-tune the expression of BioBrick parts and devices. Fortuna, Patrick 2010-12-04 36 Joint Degrees & Promotion towards European Students Computer...

  12. Promoting Children's Understanding And Interest In Science Through Informal Science Education

    E-Print Network [OSTI]

    Colorado at Boulder, University of

    Promoting Children's Understanding And Interest In Science Through Informal Science Education for Informal Science Education in the Community (PISEC) in which university participants work in afterschool beliefs about science. Keywords: Physics education research, informal science education, elementary school

  13. Promoting Successful Restoration through Effective Monitoring in the Chesapeake Bay Watershed

    E-Print Network [OSTI]

    Palmer, Margaret A.

    for their assistance in arranging the web-based reviews. #12;3 Stream Restoration from stream restoration. Since most restoration is at the reach scale1 Promoting Successful Restoration through Effective Monitoring

  14. Economic Impact of Alternative Growth Promotant Strategies on the United States Beef Industry.

    E-Print Network [OSTI]

    Williams, R. Lynn; Dietrich, R.A.; Byers, F.M.

    1991-01-01T23:59:59.000Z

    - -TDOC Z TA24S .7 8873 NO.1701 ? ? B-1701 December 1991 of Alternative Growth Promotant Strategies on the United States Beef Industry The Texas Agricultural Experiment Station J. Charles Lee, Interim Director The Texas A&M University...

  15. Instructional Practices that Promote Acquisition and Generalization of Skills by Learning Disabled Adolescents

    E-Print Network [OSTI]

    Deshler, Donald D.; Alley, Gordon R.; Warner, Michael M.; Schumaker, Jean B.

    1980-01-01T23:59:59.000Z

    While most efforts in programming for learning disabled adolescents have been directed to the content of instructional offering, the authors identify procedures to promote acquisition and generalization of skills . Exemplified ...

  16. New Media Interventions in Youth Sexual Health Promotion and HIV/STI Prevention

    E-Print Network [OSTI]

    Brown III, William

    2010-01-01T23:59:59.000Z

    Sexual Health Promotion and Disease Prevention: ISIS As anan evaluation proposal for ISIS inc. , and to have beenLevine, Executive Director of ISIS Inc. , and her team for

  17. Methods for promoting wound healing and muscle regeneration with the cell signaling protein Nell1

    DOE Patents [OSTI]

    Culiat, Cymbeline T

    2014-11-04T23:59:59.000Z

    The present invention provides methods for promoting wound healing and treating muscle atrophy in a mammal in need. The method comprises administering to the mammal a Nell1 protein or a Nell1 nucleic acid molecule.

  18. Methods for promoting wound healing and muscle regeneration with the cell signaling protein Nell1

    SciTech Connect (OSTI)

    Culiat, Cymbeline T. (Oak Ridge, TN)

    2011-03-22T23:59:59.000Z

    The present invention provides methods for promoting wound healing and treating muscle atrophy in a mammal in need. The method comprises administering to the mammal a Nell1 protein or a Nell1 nucleic acid molecule.

  19. Chain-Growth Polymerization of 2-Chlorothiophenes Promoted by Lewis Acids

    E-Print Network [OSTI]

    Bonillo Fernandez, Baltasar

    Lewis acids promote the polymerization of several 2-chloroalkylenedioxythiophenes, providing high-molecular-weight conjugated polymers. The proposed mechanism is a cationic chain-growth polymerization, as confirmed by ...

  20. Cost-effective allocation of public funding to promote the commercialization of renewable energy technology

    E-Print Network [OSTI]

    Culver, Lauren C. (Lauren Claire)

    2009-01-01T23:59:59.000Z

    The need for new Renewable Energy Technologies (RETs) is growing with the challenge of providing affordable electricity under increasing environmental and public health constraints while promoting energy security and ...

  1. Generic Enrichment Plan Enrichment plans exist to promote the psychological well-being of laboratory animals.

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Generic Enrichment Plan Enrichment plans exist to promote the psychological well An integrated approach to behavioral management should include: 1) Environmental Enrichment a) Elements of enrichment b) Implementation processes 2) Behavioral Management a) Identifying and treating animals

  2. TOT: the association strength heuristic

    E-Print Network [OSTI]

    Choi, Hyun

    2005-11-01T23:59:59.000Z

    TOT: THE ASSOCIATION STRENGTH HEURISTIC A Dissertation by HYUN CHOI Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree... of DOCTOR OF PHILOSOPHY August 2005 Major Subject: Psychology TOT: THE ASSOCIATION STRENGTH HEURISTIC A Dissertation by HYUN CHOI Submitted to the Office of Graduate Studies of Texas A...

  3. Upstream Transmission Effects of Generic Advertising and Promotion: The Case of Soybeans

    E-Print Network [OSTI]

    Lee, Sang Hyeon

    2014-11-21T23:59:59.000Z

    . The Brazil Component of the World Soybean Model ................................... 181 Table 11. The Argentina Component of the World Soybean Model ............................. 188 Table 12. World Market Clearing Conditions of the World Soybean Model...-rider gains to Brazil and Argentina; (e) no domestic supply chain effects; (f) no global supply chain effects; (g) no checkoff investments in production research (only in demand promotion), and (h) no promotion programs at multiple levels...

  4. The oxidative dimerization of methane over promoted and unpromoted magnesium oxide monoliths

    E-Print Network [OSTI]

    Aigler, Jane Marie

    1989-01-01T23:59:59.000Z

    for the degree of MASTER OF SCIENCE May 1989 Major Subject: Chemistry THE OXIDATIVE DIMERIZATION OF METHANE OVER PROMOTED AND UNPROMOTED MAGNESIUM OxiDE MONOLITHS A Thesis by JANE MARIE AIGLER Approved as to style and content by: uns or (Chair of Commi... ee) os e (Member) nt ony (Member) a (Head of Department) May 1989 ABSTRACT The Oxidative Dimerization of Methane over Promoted and Unpromoted Magnesium Oxide Monoliths. (May 1989) Jane Marie Aigier, B. S. , Pennsylvania State University...

  5. Effects of K and Pt promoters on the performance of cobalt catalyst supported on CNTs

    SciTech Connect (OSTI)

    Zabidi, Noor Asmawati Mohd, E-mail: noorasmawati-mzabidi@petronas.com.my [Department of Fundamental and Applied Sciences, Universiti Teknologi PETRONAS, Bandar Seri Iskandar, 31750 Tronoh, Perak (Malaysia); Ali, Sardar, E-mail: alikhan-635@yahoo.com [Centralized Analytical Laboratory, Universiti Teknologi PETRONAS, Bandar Seri Iskandar, 31750 Tronoh, Perak (Malaysia); Subbarao, Duvvuri, E-mail: duvvuri-subbarao@petronas.com.my [Department of Chemical Engineering, Universiti Teknologi PETRONAS, Bandar Seri Iskandar, 31750 Tronoh, Perak (Malaysia)

    2014-10-24T23:59:59.000Z

    This paper presents a comparative study on the effects of incorporation of potassium (K) and platinum (Pt) as promoters on the physicochemical properties of cobalt catalyst. The catalyst was prepared by a wet impregnation method on a CNTs support. Samples were characterized using transmission electron microscopy (TEM), H{sub 2}-temperature-programmed reduction (TPR) and X-ray photoelectron spectroscopy (XPS) techniques. Fischer-Tropsch Synthesis (FTS) was carried out in a fixed-bed microreactor at 543 K and 1 atm, with H{sub 2}/CO?=?2v/v and space velocity, SV of 12 L/g.h for 5 hours. The K-promoted and Pt-promoted Co catalysts have different physicochemical properties and catalytic performances compared to that of the un-promoted Co catalyst. XPS analysis revealed that K and Pt promoters induced electronic modifications as exhibited by the shifts in the Co binding energies. Incorporation of 0.06 wt% K and 0.06 wt% Pt in Co/CNTs catalyst resulted in an increase in the CO conversion and C{sub 5+} selectivity and a decrease in methane selectivity. Potassium was found to be a better promoter for Co/CNTs catalyst compared to platinum.

  6. AGA encouraging industry to adopt gas option. [American Gas Association

    SciTech Connect (OSTI)

    Lawrence, G.H.

    1980-03-03T23:59:59.000Z

    The American Gas Association (AGA) supports a policy of increasing conventional natural gas production and sustaining the higher level for at least 40 years in addition to developing unconventional sources by coal gasification, methane, biomass, and other technologies. International efforts to shift from petroleum to gas are responding to the need for appropriate policies. With gas supplying 40% of the energy consumed by American buildings and by industry and agriculture, the country has a significant financial investment in equipment and distribution systems. Although deregulation of gas prices will not prevent a decline in conventional production for the next decade, new sources and technologies will combine to maintain supplies. Policies are needed to enhance the US coal gasification capability and to promote the use of dual-fired furnaces. The worldwide gas option is an appropriate to other oil-importing countries as it is to the US. (DCK)

  7. associations: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Categories Designated substances Sustainable building materials 12;Brookhaven Science Associates Drivers for Purchasing of Green 9 TUCKER BALCH ASSOCIATE PROFESSOR...

  8. association: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Categories Designated substances Sustainable building materials 12;Brookhaven Science Associates Drivers for Purchasing of Green 9 TUCKER BALCH ASSOCIATE PROFESSOR...

  9. Diffusion in associated and non-associated homologous series 

    E-Print Network [OSTI]

    Alhamid, Khalid A.

    1990-01-01T23:59:59.000Z

    ) measured diffusion coefficients at infinite dilution in associated and non-associated solvents in order to determine the effect of hydrogen bonding on the diffusion coefficient and to predict a correlation for such systems. Of these solvents, water... number. Derlacki et al. (1985) determined the diffusion coefficients for the methanol ? water system over the entire concentration range. The measurements were made at 5 and 25 'C using the diaphragm cell from which velocity correlation coefficients...

  10. Todd J. Greene Associate Professor

    E-Print Network [OSTI]

    Greene, Todd J.

    international area. Regional Studies of Rocky Mountains: Evaluated petroleum systems of Rocky Mountain basins for coalbed methane projects throughout Rocky Mountains. · Montgomery Community College Geology DepartmentTodd J. Greene Associate Professor Department of Geological and Environmental Sciences California

  11. Valley Electric Association- Net Metering

    Broader source: Energy.gov [DOE]

    The Board of Directors for Valley Electric Association (VEA) approved net metering in April 2008. The rules apply to systems up to 30 kW, though owners of larger systems may be able to negotiate...

  12. Associate Vice President Human Resources

    E-Print Network [OSTI]

    Arnold, Jonathan

    Associate Vice President Human Resources Enjoy Athens! Great schools Affordable housing Eclectic Vice President for Human Resources. This position reports directly to the Vice President for Finance and Administration and provides leadership for the University's human resources programs and services

  13. Raquel Meyer Alexander Associate Professor

    E-Print Network [OSTI]

    Marsh, David

    Raquel Meyer Alexander Associate Professor Washington and Lee University Williams School;Raquel Meyer Alexander 2 Teaching strategies to embed arts in business curriculum included in The Campus;Raquel Meyer Alexander 3 preceding adoption of FIN 48" wi

  14. Association

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA Approved:AdministrationAnalysisDarby/%2AO 474.2 Chg 1KANSASVisit2a single

  15. Association

    National Nuclear Security Administration (NNSA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA Approved:AdministrationAnalysisDarby/%2AO 474.2 Chg 1KANSASVisit2a

  16. Regenerable MgO promoted metal oxide oxygen carriers for chemical looping combustion

    DOE Patents [OSTI]

    Siriwardane, Ranjani V.; Miller, Duane D.

    2014-08-19T23:59:59.000Z

    The disclosure provides an oxygen carrier comprised of a plurality of metal oxide particles in contact with a plurality of MgO promoter particles. The MgO promoter particles increase the reaction rate and oxygen utilization of the metal oxide when contacting with a gaseous hydrocarbon at a temperature greater than about 725.degree. C. The promoted oxide solid is generally comprised of less than about 25 wt. % MgO, and may be prepared by physical mixing, incipient wetness impregnation, or other methods known in the art. The oxygen carrier exhibits a crystalline structure of the metal oxide and a crystalline structure of MgO under XRD crystallography, and retains these crystalline structures over subsequent redox cycles. In an embodiment, the metal oxide is Fe.sub.2O.sub.3, and the gaseous hydrocarbon is comprised of methane.

  17. ECRbase: Database of Evolutionary Conserved Regions, Promoters, and Transcription Factor Binding Sites in Vertebrate Genomes

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Loots, Gabriela G. [LLNL; Ovcharenko, I. [LLNL

    Evolutionary conservation of DNA sequences provides a tool for the identification of functional elements in genomes. This database of evolutionary conserved regions (ECRs) in vertebrate genomes features a database of syntenic blocks that recapitulate the evolution of rearrangements in vertebrates and a comprehensive collection of promoters in all vertebrate genomes generated using multiple sources of gene annotation. The database also contains a collection of annotated transcription factor binding sites (TFBSs) in evolutionary conserved and promoter elements. ECRbase currently includes human, rhesus macaque, dog, opossum, rat, mouse, chicken, frog, zebrafish, and fugu genomes. (taken from paper in Journal: Bioinformatics, November 7, 2006, pp. 122-124

  18. Estimating the effects of new product promotion on U.S. beef in Guatemala

    E-Print Network [OSTI]

    Leister, Amanda Marie

    2009-06-02T23:59:59.000Z

    for Central America that the most effective way to launch the new beef products was to focus on one specific importer of U.S. meat. The firm Alimentos Campe?n was identified as the key HRI supplier to support the promotion. Marketing activities included... February, 2007 are provided by Alimentos Campe?n. The study is restricted to the changes in U.S. beef value cut quantity sold by Alimentos Campe?n as a response to prices and the new product promotion activities conducted. The endogenous variable...

  19. Promoting electricity from renewable energy sources -- lessons learned from the EU, U.S. and Japan

    E-Print Network [OSTI]

    Haas, Reinhard

    2008-01-01T23:59:59.000Z

    balancing associated to intermittent production from some RES-E technologies, in particular wind power

  20. Semantic associative network for text analysis (SANTA)

    E-Print Network [OSTI]

    Airhart, Robert William

    2000-01-01T23:59:59.000Z

    Based on theories of associations, the Semantic Associative Network for Text Analysis (SANTA) has been developed. Nodes in the network represent words and links between nodes represent the association strengths between them. The links are adjusted...

  1. Hyphal Development in Candida albicans Requires Two Temporally Linked Changes in Promoter Chromatin for Initiation and Maintenance

    E-Print Network [OSTI]

    Lu, Yang; Su, Chang; Wang, Allen; Liu, Haoping; Heitman, Joseph

    2011-01-01T23:59:59.000Z

    Chromatin for Initiation and Maintenance Yang Lu, Chang Su,cAMP-PKA pathway. Maintenance requires promoter recruitmentof Hda1 for hyphal maintenance happens only during the

  2. POLICY SUMMARY BUSINESS ASSOCIATE CONTRACTS

    E-Print Network [OSTI]

    Oliver, Douglas L.

    POLICY SUMMARY BUSINESS ASSOCIATE CONTRACTS POLICY NUMBER 2003-04 To comply with HIPAA requirements PRIVACY AND SECURITY POLICY NUMBER 2003-07 To identify the mechanism by which appropriate staff receives policies related to security and privacy of protected health information. BREACHES OF PRIVACY & SECURITY

  3. National Electrical Manufacturers Association (NEMA) Response...

    Energy Savers [EERE]

    Electrical Manufacturers Association (NEMA) Response to Smart Grid RFI National Electrical Manufacturers Association (NEMA) Response to Smart Grid RFI The National Electrical...

  4. Immunological Memory is Associative Derek J. Smith

    E-Print Network [OSTI]

    Somayaji, Anil

    Immunological Memory is Associative Derek J. Smith Department of Computer Science University of New , 1989; Nara & Goudsmit, 1990; Smith, 1994). Immunologists refer to associative recall as a cross

  5. Known Challenges Associated with the Production, Transportation...

    Office of Environmental Management (EM)

    Known Challenges Associated with the Production, Transportation, Storage and Usage of Pyrolysis Oil in Residential and Industrial Settings Known Challenges Associated with the...

  6. Geothermal Energy Association Recognizes the National Geothermal...

    Energy Savers [EERE]

    Geothermal Energy Association Recognizes the National Geothermal Data System Geothermal Energy Association Recognizes the National Geothermal Data System July 29, 2014 - 8:20am...

  7. Accelerating CHP Deployment, United States Energy Association...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Accelerating CHP Deployment, United States Energy Association (USEA), August 2011 Accelerating CHP Deployment, United States Energy Association (USEA), August 2011 The United...

  8. Preliminary Notice of Violation, Brookhaven Science Associates...

    Office of Environmental Management (EM)

    Brookhaven Science Associates, LLC - WEA-2013-01 Preliminary Notice of Violation, Brookhaven Science Associates, LLC - WEA-2013-01 August 29, 2013 Issued to Brookhaven Science...

  9. Spanish Association for the Internationalisation and Innovation...

    Open Energy Info (EERE)

    Spanish Association for the Internationalisation and Innovation of Solar Companies Jump to: navigation, search Name: Spanish Association for the Internationalisation and Innovation...

  10. Moore honored with American Statistical Association award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    American Statistical Association Award Moore honored with American Statistical Association award Lisa Moore is the recipient of the 2013 Don Owen Award presented by the American...

  11. American Wind Energy Association Offshore WINDPOWER Conference...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    American Wind Energy Association Offshore WINDPOWER Conference & Exhibition American Wind Energy Association Offshore WINDPOWER Conference & Exhibition October 7, 2014 9:00AM EDT...

  12. James Anderson Associate Vice President for

    E-Print Network [OSTI]

    Barrash, Warren

    James Anderson Associate Vice President for Enrollment Services Kim Asbury Coordinator of Class Wilkins Mary Barker Management Systems Coordinator Kristine M. Collins, Registrar Mandy Nelson Associate

  13. Appointment, Promotions, and Tenure Miller School of Medicine Office of Faculty Affairs

    E-Print Network [OSTI]

    Miami, University of

    1 Appointment, Promotions, and Tenure Miller School of Medicine Office of Faculty Affairs I care as well as provide for the future of medicine through training and research. Our support of our-tenure timetables Yearly renewal o Tenure "clock" 3rd year special (midpoint) review; assessed for progress

  14. Research and Reality: Using Mobile Messages to Promote Maternal Health in Rural India

    E-Print Network [OSTI]

    Canny, John

    Research and Reality: Using Mobile Messages to Promote Maternal Health in Rural India Divya for improving maternal health practices in rural India. Specifically, we investigate the use of mobile phone- nication Technology, India, Email: vivek goswami@daiict.ac.in. Canny is a professor at the University

  15. A Multiobjective Evolutionary Fuzzy System for Promoter Discovery in E. coli

    E-Print Network [OSTI]

    Granada, Universidad de

    as complementary and synergistic partners rather than competing methodologies. In particular, genetic fuzzy systemsA Multiobjective Evolutionary Fuzzy System for Promoter Discovery in E. coli Roc´io C. Romero Zaliz-motifs because of the uncertainty existing in the distance between them. However, our methodology solves

  16. High-Affinity DNA Base Analogs as Supramolecular, Nanoscale Promoters of Macroscopic Adhesion

    E-Print Network [OSTI]

    Sottos, Nancy R.

    High-Affinity DNA Base Analogs as Supramolecular, Nanoscale Promoters of Macroscopic Adhesion Cyrus and Engineering, § Beckman Institute for Advanced Science and Technology, and Department of Materials Science and manufac- tured coatings and composites. Supramolecular interactions are often implicated in various

  17. The China Prize Essay Contest and the Late Qing Promotion of Modern Science Benjamin A. Elman

    E-Print Network [OSTI]

    Elman, Benjamin

    The China Prize Essay Contest and the Late Qing Promotion of Modern Science Benjamin A. Elman of the nineteenth century was the "seeding time" for the modernization of China. During the period from 1850 to 1870-1897) devised the "China Prize Essay Contest" (Gezhi shuyuan keyi ) in 1886. The essay writing contest

  18. Identification and Characterization of Bovine Pol III Promoters to Express a Short-Hairpin RNA

    E-Print Network [OSTI]

    Peoples, Michael D 1978-

    2010-12-08T23:59:59.000Z

    ). Each bPol III promoter was able to express a functional shRNA resulting in a reduction of luciferase activity greater than 68 percent. The bH1 and bU6-2 Luc shRNA vectors were the most effective vectors when transfected with >76 percent (p-value <0...

  19. Revue Mdecine Vtrinaire, 2000, 151, 2, 99-104 Mechanism of antimicrobial growth promoters used in

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    . Antimicrobial growth promoters also decrease the fermentation of carbohydrates and the decomposition of bile to a reduced turnover in the gut epithelium. In cattle, the rumen flora fermentations are oriented toward propionic acid production, instead of acetic acid, favouring the meat deposit, and less methane is produced

  20. Promoting good relations on campus: a guide for higher and further education

    E-Print Network [OSTI]

    Mottram, Nigel

    Promoting good relations on campus: a guide for higher and further education #12;Acknowledgments) and ECU thanks all those involved in the earlier publications. This guidance updates changes to the law to thank the following people and organisations for their advice in producing this updated guidance

  1. NRRI's Bill Berguson promotes fast-growing trees as part of America's new energy future.

    E-Print Network [OSTI]

    Netoff, Theoden

    NRRI's Bill Berguson promotes fast-growing trees as part of America's new energy future. Winter in 2005 by the Departments of Energy and Agriculture concluded that, with the current supply of forest and agricultural land, the United States should be able to produce nearly one billion dry tons of biomass annually

  2. RESEARCH ARTICLE STEM CELLS AND REGENERATION Nuclear to cytoplasmic shuttling of ERK promotes differentiation of

    E-Print Network [OSTI]

    Klein, Ophir

    RESEARCH ARTICLE STEM CELLS AND REGENERATION Nuclear to cytoplasmic shuttling of ERK promotes disorders. The extracellular signal-regulated kinase 1/2 (ERK) signaling pathway is one of the most molecule (e.g. ERK) can regulate two opposing cellular outcomes is still a mystery. Using both chick

  3. Promoting the Benefits of Geospatial Data and Applications NebraskaView

    E-Print Network [OSTI]

    Nebraska-Lincoln, University of

    Promoting the Benefits of Geospatial Data and Applications NebraskaView Center for Advanced Land-Lincoln Geospatial Information for Nebraska Since the early 1970's, billions of dollars have been spent by the federal government and private sector on satellite-based earth observing systems. Hundreds of geospatial

  4. YOUNG ENTREPRENEUR PROGRAM The Indiana Economic Development Corporation (IEDC) is promoting

    E-Print Network [OSTI]

    YOUNG ENTREPRENEUR PROGRAM The Indiana Economic Development Corporation (IEDC) is promoting a reality in Indiana. The IEDC will work with local and regional communities to offer incentives to the Young Entrepreneurs with the best business plans. These incentives can include and are not limited to

  5. CS233917-AF National Center for Chronic Disease Prevention and Health Promotion

    E-Print Network [OSTI]

    CS233917-AF National Center for Chronic Disease Prevention and Health Promotion Division, Physical Activity, and Obesity Profile Obesity has important consequences on our nation's health by unhealthy options when it comes to diet and physical activity.We need public health approaches that make

  6. Identifying the promoter features governing differential kinetics of co-regulated genes using fuzzy expressions

    E-Print Network [OSTI]

    Granada, Universidad de

    of the biggest challenges in genomics is the elucidation of the design principles controlling gene expression features used by a transcriptional regulator to differentially control genes that display distinctIdentifying the promoter features governing differential kinetics of co-regulated genes using fuzzy

  7. Enhancement of photosynthesis (CO2 uptake) and plant growth through the promotion of stomatal opening

    E-Print Network [OSTI]

    Takahashi, Ryo

    1 Enhancement of photosynthesis (CO2 uptake) and plant growth through the promotion of stomatal ­ By determining the key factor in regulating photosynthesis and plant growth, scientists, Prof. Toshinori-Molecules (WPI-ITbM), have succeeded in developing a method to increase photosynthesis (CO2 uptake) and plant

  8. EXPRESSION OF BRUCELLA GENES REQUIRED FOR LIPOPOLYSACCARIDE PRODUCTION UNDER THE CONTROL OF ARAC AND PTAC PROMOTERS

    E-Print Network [OSTI]

    Han, Shuo

    2006-08-16T23:59:59.000Z

    virulence mechanism in Brucella. The main objective of this project was to design an inducible system that would allow or prevent the expression of LPS using the manBA genes which encode components of LPS through the regulation of different promoters, p...

  9. IEECB'08 Paper n57 Can energy savings from operations promoting energy efficient

    E-Print Network [OSTI]

    Boyer, Edmond

    1 IEECB'08 Paper n°57 Can energy savings from operations promoting energy efficient behaviors in office buildings be accounted for ? Abstract When looking for solutions to mitigate the growth of energy consumption in the commercial buildings sector, research works often focus on the energy performance

  10. Solvent-Promoted Self-Healing Epoxy Materials Mary M. Caruso, David A. Delafuente, Victor Ho,

    E-Print Network [OSTI]

    Sottos, Nancy R.

    , which can lead to cracking of the epoxy resin.2 Microcracks are often contained deep within a structural in an epoxy resin required high-temperature conditions greater than 250 °F (121 °C).4 After fractureSolvent-Promoted Self-Healing Epoxy Materials Mary M. Caruso, David A. Delafuente, Victor Ho, Nancy

  11. Developing microbeplant interactions for applications in plant-growth promotion and disease control,

    E-Print Network [OSTI]

    Chen, Wilfred

    and disease control, production of useful compounds, remediation and carbon sequestration Cindy H. Wu,1-growth promotion, biocontrol, bioactive compound and biomaterial production, remediation and carbon sequestration economical (Anderson et al., 1993). Carbon sequestration through plant­rhizosphere processes is a potentially

  12. P\\procedure\\FP#36 TITLE: GREEN BUILDING POLICY PROMOTING ENVIRONMENTAL QUALITY AND

    E-Print Network [OSTI]

    Fernandez, Eduardo

    P\\procedure\\FP#36 TITLE: GREEN BUILDING POLICY PROMOTING ENVIRONMENTAL QUALITY AND RESOURCE the U.S. Green Building Council's LEED Silver standard or equivalent. This policy will be limited% of building replacement value". RESPONSIBILITY: ACTION FACILITIES PLANNING DIRECTOR Ensure that the green

  13. Z-Selective Olefin Metathesis Reactions Promoted by Tungsten Oxo Alkylidene Complexes

    E-Print Network [OSTI]

    Müller, Peter

    Z-Selective Olefin Metathesis Reactions Promoted by Tungsten Oxo Alkylidene Complexes Dmitry V). Early in the development of olefin metathesis catalysts that contain tungsten, it was shown that metathetically more active and reproducible systems were produced when tungsten oxo complexes were deliberately

  14. Contact promotion et diffusion Emmanuelle Mouche Editions L'Harmattan -Sciences Humaines

    E-Print Network [OSTI]

    promotion et diffusion Emmanuelle Mouche ­ Editions L'Harmattan - Sciences Humaines 7, rue de l'�cole Polytechnique 75005 Paris Tél : 01 40 46 79 22 / Fax : 01 43 25 82 03 / emmanuelle.mouche@harmattan.fr L-7 rue de l'Ecole Polytechnique 75005 PARIS www.editions-harmattan.fr AVIS DE PARUTION #12;SOMMAIRE

  15. Heart Failure Symposium: Promoting Knowledge and Self-Care: The Keys to

    E-Print Network [OSTI]

    Kim, Duck O.

    Heart Failure Symposium: Promoting Knowledge and Self-Care: The Keys to a Woman's Healthy Heart This is the Fourth Annual UConn Health Center Heart Failure Symposium. This year we will focus on women and heart disease. The program will include presentations on heart disease and healthy living for women

  16. Using Mobile Phones for Promoting Water Conservation Rahuvaran Pathmanathan1, 2

    E-Print Network [OSTI]

    Pearce, Jon

    of when they were allowed to water their gardens, but there was and is still a lack of knowledge243 Using Mobile Phones for Promoting Water Conservation Rahuvaran Pathmanathan1, 2 , Jon Pearce2@unimelb.edu.au ABSTRACT We report a design investigation that seeks to help people to conserve water in their homes

  17. Energy Policy 35 (2007) 91111 Simulating price patterns for tradable green certificates to promote

    E-Print Network [OSTI]

    Ford, Andrew

    2007-01-01T23:59:59.000Z

    Energy Policy 35 (2007) 91­111 Simulating price patterns for tradable green certificates to promote to these high prices with construction of new wind capacity. After a few years, wind generation meets the market opens. Investors react to these high prices with construction of new wind capacity, and total

  18. Hydrotropic salt promotes anionic surfactant self-assembly into vesicles and ultralong fibers

    E-Print Network [OSTI]

    Huang, Jianbin

    Hydrotropic salt promotes anionic surfactant self-assembly into vesicles and ultralong fibers November 2011 Available online 6 December 2011 Keywords: Surfactant self-assembly Hydrotropic salt Fiber dodecylbenzene sulfo- nate, SDBS) and a hydrotropic salt (benzylamine hydrochloride, BzCl) in aqueous solution

  19. Puerto Rico SPH and Indiana HPER Develop Sexual Health Promotion Partnership

    E-Print Network [OSTI]

    Quirk, Gregory J.

    Puerto Rico SPH and Indiana HPER Develop Sexual Health Promotion Partnership The University of Puerto Rico School of Public Health (UPR-SPH) and Indiana University ­ Bloomington School of Health, Physical Education and Recreation (IU-HPER) celebrated a meeting in San Juan, Puerto Rico to establish

  20. Online Social Networks for Personal Informatics to Promote Positive Health Behavior

    E-Print Network [OSTI]

    British Columbia, University of

    Online Social Networks for Personal Informatics to Promote Positive Health Behavior Noreen Kamal.ho@ubc.ca ABSTRACT Social network services are becoming increasingly popular, and people are using these networks to obtain and share information. The application of social network and social media to the collection

  1. Energy Policy 36 (2008) 15381544 Promoting biofuels: Implications for developing countries

    E-Print Network [OSTI]

    2008-01-01T23:59:59.000Z

    Energy Policy 36 (2008) 1538­1544 Promoting biofuels: Implications for developing countries Jo¨ rg 2008 Abstract Interest in biofuels is growing worldwide as concerns about the security of energy supply, however, production costs of biofuels are typically much higher than those of fossil fuels. As a result

  2. Secure Pesticide Storage: Security and Safety-promoting Features of Pesticide Storage Facilities1

    E-Print Network [OSTI]

    Watson, Craig A.

    PI32 Secure Pesticide Storage: Security and Safety-promoting Features of Pesticide Storage pesticide storage facility security and safety. Introduction In actual practice, the fundamental goal of "security" is always the same: effective safeguard. Therefore, certain features of a pesticide storage

  3. Promoting Lower-Carbon Lifestyles The role of personal values, climate change communications and

    E-Print Network [OSTI]

    Promoting Lower-Carbon Lifestyles The role of personal values, climate change communications for more research that looks at the effects of climate change communications on behaviour and not just ---------------------------------------------------------------------------------------------- Climate change is a pressing problem and substantial reductions in the greenhouse gas emissions that cause

  4. Tyrosinase-Related Protein 2 Promoter Targets Transgene Expression to Ocular and Neural

    E-Print Network [OSTI]

    Cummings, Molly E.

    Tyrosinase-Related Protein 2 Promoter Targets Transgene Expression to Ocular and Neural Crest generated transgenic mice carrying the lacZ reporter gene linked to the tyrosinase-related protein 2 (TRP2 mutation. INTRODUCTION Tyrosinase-related protein 2 (TRP2) is an enzyme in- volved in an intermediate step

  5. Promoting electricity from renewable energy sources -- lessons learned from the EU, U.S. and Japan

    SciTech Connect (OSTI)

    Haas, Reinhard; Meyer, Niels I.; Held, Anne; Finon, Dominique; Lorenzoni, Arturo; Wiser, Ryan; Nishio, Ken-ichiro

    2007-06-01T23:59:59.000Z

    The promotion of electricity generated from Renewable Energy Sources (RES) has recently gained high priority in the energy policy strategies of many countries in response to concerns about global climate change, energy security and other reasons. This chapter compares and contrasts the experience of a number of countries in Europe, states in the US as well as Japan in promoting RES, identifying what appear to be the most successful policy measures. Clearly, a wide range of policy instruments have been tried and are in place in different parts of the world to promote renewable energy technologies. The design and performance of these schemes varies from place to place, requiring further research to determine their effectiveness in delivering the desired results. The main conclusions that can be drawn from the present analysis are: (1) Generally speaking, promotional schemes that are properly designed within a stable framework and offer long-term investment continuity produce better results. Credibility and continuity reduce risks thus leading to lower profit requirements by investors. (2) Despite their significant growth in absolute terms in a number of key markets, the near-term prognosis for renewables is one of modest success if measured in terms of the percentage of the total energy provided by renewables on a world-wide basis. This is a significant challenge, suggesting that renewables have to grow at an even faster pace if we expect them to contribute on a significant scale to the world's energy mix.

  6. Official Merit Promotion System and Its Impact on Climate Change Mitigation Policy in China

    E-Print Network [OSTI]

    Zhou, Pei

    on mitigating carbon emission, strengthening performance standards to control carbon standards and implementing in a long term in carbon dioxides reduction is to use its "iron hand". "Iron hand" came from Premier WenOfficial Merit Promotion System and Its Impact on Climate Change Mitigation Policy in China

  7. The Project The Southern Region Water Quality Regional Coordination Project is designed to promote regional collaboration,

    E-Print Network [OSTI]

    The Project The Southern Region Water Quality Regional Coordination Project is designed to promote to protect and restore water resources. Effective approaches for watershed management, pollution prevention to the research, extension and education resources available through the Land Grant University System

  8. Bio-inspired Promoters and Inhibitors for Self-Organized Network Security Facilities

    E-Print Network [OSTI]

    Breu, Ruth

    concentrate on attack detection as one of the major applications of network monitoring, especially DDoS@informatik.uni-erlangen.de Abstract-- Self-organization techniques based on promoters and inhibitors has been intensively studied and that gracefully degradate in case of overload situations. We created a simulation model to verify the algorithms

  9. Self-Organized Network Security Facilities based on Bio-inspired Promoters and Inhibitors

    E-Print Network [OSTI]

    Breu, Ruth

    , especially DDoS (dis- tributed denial-of-service) attacks are concerned [3,20]. Such attack detection@informatik.uni-erlangen.de Summary. Self-organization techniques based on promoters and inhibitors has been intensively studied and that gracefully degradate in case of overload situations. We created a simulation model to verify the algorithms

  10. QER- Comment of Northeast Gas Association

    Broader source: Energy.gov [DOE]

    Please find enclosed comments of the Northeast Gas Association regarding the Quadrennial Energy Review. Thank you.

  11. A Review of "Images Wars: Promoting Kings and Commonwealth in England, 1603-1660" by Kevin Sharpe

    E-Print Network [OSTI]

    Nechtman, Tillman

    2011-01-01T23:59:59.000Z

    Atlantic studies. Kevin Sharpe. Images Wars: Promoting Kings and Commonwealth in England, 1603-1660. New Haven: Yale University Press, 2010. xvii + 665 pp. $55.00. Review by tillman w. nechtman, skidmore college. Kevin Sharpe?s Image Wars: Promoting Kings...

  12. School of Journalism Criteria for Promotion and Tenure revised and approved by the Arts and Sciences Senate

    E-Print Network [OSTI]

    Walter, Frederick M.

    School of Journalism Criteria for Promotion and Tenure revised and approved by the Arts and Tenure Criteria School of Journalism Stony Brook University The School of Journalism will adhere and Sciences Senate.. Successful candidates for tenure and promotion in the School of Journalism

  13. Genome-wide Co-occurrence of Promoter Elements Reveals a cis-Regulatory Cassette of rRNA

    E-Print Network [OSTI]

    Church, George M.

    Genome-wide Co-occurrence of Promoter Elements Reveals a cis-Regulatory Cassette of r conducted a genome-wide computational survey to identify cis-regulatory motif pairs that co-occur in a significantly high number of promoters in the S. cerevisiae genome. A pair of novel motifs, mRRPE and PAC, co

  14. An Arabidopsis promoter microarray and its initial usage in the identification of HY5 binding targets in vitro

    E-Print Network [OSTI]

    Deng, Xing-Wang

    ; accepted in revised form 5 April 2004 Key words: Arabidopsis, HY5, promoter microarray, transcription of the promoter regions of annotated genes in the Arabidopsis genome. A web-interfaced primer-retrieval program insights in the genome-wide transcription regulatory network using a global genome-wide analysis

  15. Titanium(IV) Chloride Promoted Syntheses of New Imidazo[1,2-a]pyridine Derivatives under Microwave Conditions

    E-Print Network [OSTI]

    Shen, Jun

    PAPER 133 Titanium(IV) Chloride Promoted Syntheses of New Imidazo[1,2-a]pyridine Derivatives under Microwave Conditions Titanium(IV)Chloride-PromotedSynthesesofNewImidazo[1,2-a]pyridinesLisheng Cai,* Chad of 2-aminopy- ridines with a-haloketones. The critical reagent is titanium(IV) chloride, which appears

  16. Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel to

    E-Print Network [OSTI]

    Horvitz, H. Robert

    Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel in the invertebrate nematode Caenorhabditis elegans. The C. elegans genome contains four caspase genes (ced-3, csp-1, csp-2, and csp-3), of which only ced-3 has been demonstrated to promote apoptosis. Here, we show

  17. Grant Title: NIH DIRECTOR'S EARLY INDEPENDENCE AWARDS (DP5) Funding Opportunity Number: RFA-RM-12-018. CFDA Number(s): 93.310.

    E-Print Network [OSTI]

    Farritor, Shane

    -018. CFDA Number(s): 93.310. Agency/Department: Department of Health and Human Services, Office of Strategic

  18. BiofuelsMarketAlert Copyright 2010 The Kiplinger Washington Editors, Inc. 1729 H Street NW Washington, DC 20006-3938 202-887-6426

    E-Print Network [OSTI]

    Information Administration's Annual Energy Outlook 2010 EIA Foresees Biofuels Use Doubling by 2035. See page 5 groups, the Renewable Fuels Association (RFA) and Growth Energy--attacks the LCFS on constitutional-based Cellulosic Imports Green Liquids Other Biodiesel Biomass How Biofuels Are Expected to Grow Source: Energy

  19. Manipulation of lignin composition in plants using a tissue-specific promoter

    DOE Patents [OSTI]

    Chapple, Clinton C. S.

    2003-08-26T23:59:59.000Z

    The present invention relates to methods and materials in the field of molecular biology, the manipulation of the phenylpropanoid pathway and the regulation of proteins synthesis through plant genetic engineering. More particularly, the invention relates to the introduction of a foreign nucleotide sequence into a plant genome, wherein the introduction of the nucleotide sequence effects an increase in the syringyl content of the plant's lignin. In one specific aspect, the invention relates to methods for modifying the plant lignin composition in a plant cell by the introduction there into of a foreign nucleotide sequence comprising at issue specific plant promoter sequence and a sequence encoding an active ferulate-5-hydroxylase (F5H) enzyme. Plant transformants harboring an inventive promoter-F5H construct demonstrate increased levels of syringyl monomer residues in their lignin, rendering the polymer more readily delignified and, thereby, rendering the plant more readily pulped or digested.

  20. Technology certification and technology acceptance: Promoting interstate cooperation and market development for innovative technologies

    SciTech Connect (OSTI)

    Brockbank, B.R.

    1995-03-01T23:59:59.000Z

    In the past two years, public and private efforts to promote development and deployment of innovative environmental technologies have shifted from the analysis of barriers to the implementation of a variety of initiatives aimed at surmounting those barriers. Particular attention has been directed at (1) streamlining fragmented technology acceptance processes within and among the states, and (2) alleviating disincentives, created by inadequate or unverified technology cost and performance data, for users and regulators to choose innovative technologies. Market fragmentation currently imposes significant cost burdens on technology developers and inhibits the investment of private capital in environmental technology companies. Among the responses to these problems are state and federal technology certification/validation programs, efforts to standardize cost/performance data reporting, and initiatives aimed at promoting interstate cooperation in technology testing and evaluation. This paper reviews the current status of these initiatives, identifies critical challenges to their success, and recommends strategies for addressing those challenges.

  1. Infrared study of pyridine adsorbed on unpromoted and promoted sulfated zirconia

    SciTech Connect (OSTI)

    Davis, B.H.; Keogh, R.A. [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research] [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Alerasool, S. [Engelhard Corp., Beachwood, OH (United States)] [Engelhard Corp., Beachwood, OH (United States); Zalewski, D.J.; Day, D.E.; Doolin, P.K. [Ashland Petroleum Co., KY (United States)] [Ashland Petroleum Co., KY (United States)

    1999-04-01T23:59:59.000Z

    Infrared spectra of pyridine adsorbed on zirconia and Pt-zirconia exhibited bands consistent with Lewis acid sites. Sulfated zirconia, after heating at 400 C, exhibited bands indicating about equal amounts of Lewis (L) and Broensted (B) acid sites; the B/L ratio decreased with increasing reactivation temperature to become essentially zero after reactivation at 600 C. In contrast, both Pt and Fe/Mn promoted sulfated zirconia exhibited B/L ratios that increased slightly with increasing reactivation temperature. It is proposed that pyridine reacts with a Lewis acid site to produce an adsorbed pyridone-type surface species with the concurrent generation of a proton. The superior performance of the promoted sulfated zirconia catalyst is believed to arise from its ability to generate Broensted acid sites.

  2. Federal policies to promote the widespread utilization of photovoltaic systems. Supplement: review and critique

    SciTech Connect (OSTI)

    Smith, J.L.

    1980-04-15T23:59:59.000Z

    This document is intended as a supplement to the two-volume report entitled Federal Policies to Promote the Widespread Utilization of Photovoltaic Systems that was submitted to Congress by the Department of Energy in February and April of 1980. This supplement contains review comments prepared by knowledgeable experts who reviewed early drafts of the Congressional report. Responses to the review comments by the Jet Propulsion Laboratory, preparer of the Congressional report, are also included in this supplement. The Congressional report, mandated in the Solar Photovoltaic Energy Research, Development, and Demonstration Act of 1978 (P.L. 95-590), discusses various issues related to promoting the deployment of photovoltaic systems through the Federal Photovoltaic Program. Various program strategies and funding levels are examined.

  3. colloque des Archives d'Agde. Agde, 11 juin 2005 Association pour la Promotion des Archives d'Agde et de sa Rgion

    E-Print Network [OSTI]

    Boyer, Edmond

    étangs dans les plaines périphériques de la Méditerranée fait qu'ils sont au coeur, en non en marge, de l. Il faut ajouter à ce besoin strictement alimentaire en céréales une recherche du profit et de pouvoir de la part des maîtres de la terre : les seigneurs, qu'il s'agisse des laïcs (nobles locaux et

  4. H. hepaticus-induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response

    E-Print Network [OSTI]

    García, Alexis

    Chronic microbial infection influences cancer progression, but the mechanisms that link them remain unclear. Constitutive androstane receptor (CAR) is a nuclear receptor that regulates enzymes involved in endobiotic and ...

  5. Sulfur resistance of Group VIII transition metal promoted nickel catalysts for synthesis gas methanation

    E-Print Network [OSTI]

    Hamlin, Kellee Hall

    1986-01-01T23:59:59.000Z

    their resistance to deactivation by Hxg. The nickel and promoters were adsorbed on the catalyst by a simple precipitation technique. To investigate catalyst activity and deactivation experimentally, a fixed bed tubular reactor was operated at atmospheric... AND PROCEDURE To investigate catalyst activity and deactivation experimentally, a fixed bed tubular reactor wae constructed for the synthesis gss methanation studies. The reactor system and supporting equipment are shown schematically in Figure 1, while...

  6. Question & Answer with Heather Harward: H2O4Texas Coalition promotes state water plan implementations

    E-Print Network [OSTI]

    Kalisek, Danielle

    2011-01-01T23:59:59.000Z

    are conducting a statewide public education and awareness campaign hoping to invigorate Question & Answer with Heather Harward H#31;O#30;TEXAS Coalition promotes state water plan implementation 2 Texans at the grassroots and get them energized about... implementation of the plan, we need to get Texans energized about the state water plan and calling for implementation. Having the backing of Texans is important to a Legislature that will ultimately make the decision. Q: How many partners are currently...

  7. Promoting Rural Development from a Territorial Perspective: The Case of The Yeguare Region, Honduras

    E-Print Network [OSTI]

    Borja Borja, Ivan M.

    2010-07-14T23:59:59.000Z

    , Theresa P. Murphrey Timothy H. Murphy Gary W. Williams Head of Department, David W. Reed May 2009 Major Subject: Agricultural Education iii ABSTRACT Promoting Rural Development from a Territorial Perspective: The Case of the Yeguare Region... the classroom. I would like to thank Dr. Gary Williams. He motivated me to continue with my doctoral program. He was a teacher, a mentor and a true friend for me. I would like to thank Drs. Theresa Murphrey and Tim Murphy. They were advisors, teachers...

  8. Active form Notch4 promotes the proliferation and differentiation of 3T3-L1 preadipocytes

    SciTech Connect (OSTI)

    Lai, Peng-Yeh [Institute of Molecular Biology and Department of Life Science, National Chung Cheng University, Chiayi 621, Taiwan, ROC (China)] [Institute of Molecular Biology and Department of Life Science, National Chung Cheng University, Chiayi 621, Taiwan, ROC (China); Tsai, Chong-Bin [Institute of Molecular Biology and Department of Life Science, National Chung Cheng University, Chiayi 621, Taiwan, ROC (China) [Institute of Molecular Biology and Department of Life Science, National Chung Cheng University, Chiayi 621, Taiwan, ROC (China); Department of Ophthalmology, Chiayi Christian Hospital, Chiayi 600, Taiwan, ROC (China); Tseng, Min-Jen, E-mail: biomjt@ccu.edu.tw [Institute of Molecular Biology and Department of Life Science, National Chung Cheng University, Chiayi 621, Taiwan, ROC (China)] [Institute of Molecular Biology and Department of Life Science, National Chung Cheng University, Chiayi 621, Taiwan, ROC (China)

    2013-01-18T23:59:59.000Z

    Highlights: ? Notch4IC modulates the ERK pathway and cell cycle to promote 3T3-L1 proliferation. ? Notch4IC facilitates 3T3-L1 differentiation by up-regulating proadipogenic genes. ? Notch4IC promotes proliferation during the early stage of 3T3-L1 adipogenesis. ? Notch4IC enhances differentiation during subsequent stages of 3T3-L1 adipogenesis. -- Abstract: Adipose tissue is composed of adipocytes, which differentiate from precursor cells in a process called adipogenesis. Many signal molecules are involved in the transcriptional control of adipogenesis, including the Notch pathway. Previous adipogenic studies of Notch have focused on Notch1 and HES1; however, the role of other Notch receptors in adipogenesis remains unclear. Q-RT-PCR analyses showed that the augmentation of Notch4 expression during the differentiation of 3T3-L1 preadipocytes was comparable to that of Notch1. To elucidate the role of Notch4 in adipogenesis, the human active form Notch4 (N4IC) was transiently transfected into 3T3-L1 cells. The expression of HES1, Hey1, C/EBP? and PPAR? was up-regulated, and the expression of Pref-1, an adipogenic inhibitor, was down-regulated. To further characterize the effect of N4IC in adipogenesis, stable cells expressing human N4IC were established. The expression of N4IC promoted proliferation and enhanced differentiation of 3T3-L1 cells compared with those of control cells. These data suggest that N4IC promoted proliferation through modulating the ERK pathway and the cell cycle during the early stage of 3T3-L1 adipogenesis and facilitated differentiation through up-regulating adipogenic genes such as C/EBP?, PPAR?, aP2, LPL and HSL during the middle and late stages of 3T3-L1 adipogenesis.

  9. Active hopper for promoting flow of bulk granular or powdered solids

    DOE Patents [OSTI]

    Saunders, Timothy; Brady, John D.

    2013-04-02T23:59:59.000Z

    An apparatus that promotes the flow of materials has a body having an inner shape for holding the materials, a wall having a shape that approximates a portion of the inner shape of the body, and a vibrator attached to the wall. The wall may be disposed vertically within the body close to the body's inner shape. The vibrator transfers vibrations to the wall to agitate the material and encourage material flow.

  10. Contact promotion et diffusion Emmanuelle Mouche Editions L'Harmattan -Sciences Humaines

    E-Print Network [OSTI]

    van Tiggelen, Bart

    promotion et diffusion Emmanuelle Mouche ­ Editions L'Harmattan - Sciences Humaines 7, rue de l'�cole Polytechnique 75005 Paris Tél : 01 40 46 79 22 / Fax : 01 43 25 82 03 / emmanuelle.mouche@harmattan.fr �dition ­ Diffusion 5-7, rue de l'�cole Polytechnique 75005 Paris Tél : 01 40 46 79 20 / Fax : 01 43 25 82 03 http://www.editions-harmattan

  11. Determination of Baselines for Evaluation and Promotion of Energy Efficiency in Wastewater Treatment Facilities

    E-Print Network [OSTI]

    Chow, S. A.; Ganji, A. R.; Fok, S.

    to facilitate the design and implementation of energy efficiency and demand response programs in wastewater treatment plants for PG&E?s 2009-2011 program cycle. An overview of activities by PG&E and the U.S. to promote energy efficiency in wastewater..., research and development project addressing energy efficiency in these plants, case studies on energy efficient equipment and best practices. Information gathered from the literature search was used in conjunction with the administered survey...

  12. Nickel-promoted reductive C-S bond cleavage: A model for the first step in the reaction promoted by methyl coenzyme M reductase

    SciTech Connect (OSTI)

    Mikyung Cha; Shoner, S.C.; Kovacs, J.A. (Univ. of Washington, Seattle (United States))

    1993-04-28T23:59:59.000Z

    Sulfur-ligated Ni complexes are of interest as active-site models of the Ni-containing enzymes hydrogenase (H[sub 2]-ase), methyl coenzyme M reductase (Me-CoM reductase), and Co-dehydrogenase (CODH). Me-CoM reductase catalyzes the last step in the reaction sequence which converts CO[sub 2] to CH[sub 4] in methanogenic bacteria. This step involves the cleavage of the methyl thioether C-S bond of the substrate methyl coenzyme M (Me-S-CoM). Ni(I) is believed to be the active species responsible for promoting this reaction. However, it has been difficult to probe the mechanism by which this occurs, since Me-CoM reductase rapidly loses activity upon breakage of whole cells during purification. Only one Ni complex, Ni[sup II](dioxo[16]aneN[sub 5]), has been shown to induce stoichiometric methane formation from Me-S-CoM; however, the mechanism proposed to explain this reaction is difficult to understand, and involves a Ni(II/III), as opposed to a Ni(I/II), redox couple. Other nickel complexes have been shown to desulfurize thioethers in the presence of reducing agents (e.g., LiAlH[sub 4]); however, the reactive Ni species have not been characterized. As part of a systematic study aimed at determining the influence of the local Ni coordination environment on reactivity, the authors have synthesized a series of structurally related sulfur-ligated Ni(II) complexes, including Ni[sup II]L[sub S5] (1). Since redox changes (Ni(III) [yields] Ni(II) and/or Ni(II) [yields] Ni(I)) appear to play an important role in the mechanisms of the enzymes mentioned above, the authors have also examined the redox chemistry of these molecules. Herein, they report a Ni-promoted reductive C-S bond cleavage reaction that represents a plausible chemical model for the first step in the reaction promoted by Ni in Me-CoM reductase. 30 refs., 4 figs.

  13. Neural regeneration protein is a novel chemoattractive and neuronal survival-promoting factor

    SciTech Connect (OSTI)

    Gorba, Thorsten [Neuren Pharmaceuticals Ltd., PO Box 9923, Newmarket, Auckland 1031 (New Zealand); Liggins Institute, University of Auckland, 2-6 Park Avenue, Grafton, Auckland (New Zealand); Bradoo, Privahini [Liggins Institute, University of Auckland, 2-6 Park Avenue, Grafton, Auckland (New Zealand); Antonic, Ana [Liggins Institute, University of Auckland, 2-6 Park Avenue, Grafton, Auckland (New Zealand); Marvin, Keith [Neuren Pharmaceuticals Ltd., PO Box 9923, Newmarket, Auckland 1031 (New Zealand); Liu, Dong-Xu [Liggins Institute, University of Auckland, 2-6 Park Avenue, Grafton, Auckland (New Zealand); Lobie, Peter E. [Liggins Institute, University of Auckland, 2-6 Park Avenue, Grafton, Auckland (New Zealand); Reymann, Klaus G. [Leibnitz Institute for Neurobiology, Brenneckestrasse 6, 39118 Magdeburg (Germany); Gluckman, Peter D. [Liggins Institute, University of Auckland, 2-6 Park Avenue, Grafton, Auckland (New Zealand); Sieg, Frank [Neuren Pharmaceuticals Ltd., PO Box 9923, Newmarket, Auckland 1031 (New Zealand)]. E-mail: fsieg@neurenpharma.com

    2006-10-01T23:59:59.000Z

    Neurogenesis and neuronal migration are the prerequisites for the development of the central nervous system. We have identified a novel rodent gene encoding for a neural regeneration protein (NRP) with an activity spectrum similar to the chemokine stromal-derived factor (SDF)-1, but with much greater potency. The Nrp gene is encoded as a forward frameshift to the hypothetical alkylated DNA repair protein AlkB. The predicted protein sequence of NRP contains domains with homology to survival-promoting peptide (SPP) and the trefoil protein TFF-1. The Nrp gene is first expressed in neural stem cells and expression continues in glial lineages. Recombinant NRP and NRP-derived peptides possess biological activities including induction of neural migration and proliferation, promotion of neuronal survival, enhancement of neurite outgrowth and promotion of neuronal differentiation from neural stem cells. NRP exerts its effect on neuronal survival by phosphorylation of the ERK1/2 and Akt kinases, whereas NRP stimulation of neural migration depends solely on p44/42 MAP kinase activity. Taken together, the expression profile of Nrp, the existence in its predicted protein structure of domains with similarities to known neuroprotective and migration-inducing factors and the high potency of NRP-derived synthetic peptides acting in femtomolar concentrations suggest it to be a novel gene of relevance in cellular and developmental neurobiology.

  14. Identification and characterization of an alternative promoter of the human PGC-1{alpha} gene

    SciTech Connect (OSTI)

    Yoshioka, Toyo; Inagaki, Kenjiro [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Noguchi, Tetsuya, E-mail: noguchi@med.kobe-u.ac.jp [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Sakai, Mashito; Ogawa, Wataru; Hosooka, Tetsuya [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Iguchi, Haruhisa; Watanabe, Eijiro; Matsuki, Yasushi; Hiramatsu, Ryuji [Genomic Science Laboratories, DainipponSumitomo Pharma Co. Ltd., 4-2-1 Takatsukasa, Takarazuka 665-8555 (Japan)] [Genomic Science Laboratories, DainipponSumitomo Pharma Co. Ltd., 4-2-1 Takatsukasa, Takarazuka 665-8555 (Japan); Kasuga, Masato [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan) [Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655 (Japan)

    2009-04-17T23:59:59.000Z

    The transcriptional regulator peroxisome proliferator-activated receptor-{gamma} coactivator-1{alpha} (PGC-1{alpha}) controls mitochondrial biogenesis and energy homeostasis. Although physical exercise induces PGC-1{alpha} expression in muscle, the underlying mechanism of this effect has remained incompletely understood. We recently identified a novel muscle-enriched isoform of PGC-1{alpha} transcript (designated PGC-1{alpha}-b) that is derived from a previously unidentified first exon. We have now cloned and characterized the human PGC-1{alpha}-b promoter. The muscle-specific transcription factors MyoD and MRF4 transactivated this promoter through interaction with a proximal E-box motif. Furthermore, either forced expression of Ca{sup 2+}- and calmodulin-dependent protein kinase IV (CaMKIV), calcineurin A, or the p38 mitogen-activated protein kinase (p38 MAPK) kinase MKK6 or the intracellular accumulation of cAMP activated the PGC-1{alpha}-b promoter in cultured myoblasts through recruitment of cAMP response element (CRE)-binding protein (CREB) to a putative CRE located downstream of the E-box. Our results thus reveal a potential molecular basis for isoform-specific regulation of PGC-1{alpha} expression in contracting muscle.

  15. Selective methane oxidation over promoted oxide catalysts. Quarterly report, March--May 1995

    SciTech Connect (OSTI)

    Klier, K.; Herman, R.G.; Wang, Chaun-Bao; Shi, Chunlei; Sun, Qun

    1995-08-01T23:59:59.000Z

    The objective of this research is the selective oxidative coupling of methane to C{sub 2}H{sub 4} hydrocarbons and oxygenates, in particular formaldehyde and methanol. Air, oxygen or carbon dioxide, rather than nitrous oxide will be utilized as the oxidizing gas at high gas hourly space velocity, but mild reaction conditions (500-700 {degrees}C, 1 atm total pressure). All the investigated processes are catalytic, aiming at minimizing gas phase reactions that are difficult to control. The research is divided into the following three tasks: (1) maximizing selective methane oxidation to C{sub 2}H{sub 4} products over promoted Sr/La{sub 2}O{sub 3}; (2) selective methane oxidation to oxygenates; and (3) catalyst characterization and optimization. Task 1 dealt with the preparation, testing, and optimization of acidic promoted lanthana-based catalysts for the synthesis of C{sub 2}H{sub 4} hydrocarbons and is essentially completed. Task 2 aims at the formation and optimization of promoted catalysts for the synthesis of oxygenates, in particular formaldehyde and methanol. Task 3 involves characterization of the most promising catalysts so that optimization can be achieved under Task 2. Accomplishments for this period are presented.

  16. South Asia Water Resources Workshop: An effort to promote water quality data sharing in South Asia

    SciTech Connect (OSTI)

    RAJEN,GAURAV; BIRINGER,KENT L.; BETSILL,J. DAVID

    2000-04-01T23:59:59.000Z

    To promote cooperation in South Asia on environmental research, an international working group comprised of participants from Bangladesh, India, Nepal, Pakistan, Sri Lanka, and the US convened at the Soaltee Hotel in Kathmandu, Nepal, September 12 to 14, 1999. The workshop was sponsored in part by the Cooperative Monitoring Center (CMC) at Sandia National Laboratories in Albuquerque, New Mexico, through funding provided by the Department of Energy (DOE) Office of Nonproliferation and National Security. The CMC promotes collaborations among scientists and researchers in regions throughout the world as a means of achieving common regional security objectives. In the long term, the workshop organizers and participants are interested in the significance of regional information sharing as a means to build confidence and reduce conflict. The intermediate interests of the group focus on activities that might eventually foster regional management of some aspects of water resources utilization. The immediate purpose of the workshop was to begin the implementation phase of a project to collect and share water quality information at a number of river and coastal estuary locations throughout the region. The workshop participants achieved four objectives: (1) gaining a better understanding of the partner organizations involved; (2) garnering the support of existing regional organizations promoting environmental cooperation in South Asia; (3) identifying sites within the region at which data is to be collected; and (4) instituting a data and information collection and sharing process.

  17. Genetic analysis of the stationary-phase induced and [sigma]S-independent promoter of the mcb operon in Escherichia coli

    E-Print Network [OSTI]

    Mao, Weimin

    1997-01-01T23:59:59.000Z

    , suggesting that they use the same transcriptional start site. Random mutagenesis was performed to identify the bases important for promoter activity. Mutations at-8,-11,-30, -31 and-32 greatly decreased promoter activity. These sites might have contact...

  18. GREEN FUNCTIONS ASSOCIATED TO COMPLEX REFLECTION GROUPS

    E-Print Network [OSTI]

    Shoj, Toshiaki

    GREEN FUNCTIONS ASSOCIATED TO COMPLEX REFLECTION GROUPS University of Tokyo Noda, Chiba 278-8510, Japan Abstract. Green functions called symbols. Generali* *zing this, we define Green functions associated to complex reflection

  19. QER- Comment of Canadian Gas Association

    Broader source: Energy.gov [DOE]

    SENT ON BEHALF OF TIMOTHY M. EGAN PRESIDENT AND CEO CANADIAN GAS ASSOCIATION Dear Quadrennial Energy Review Task Force, Please find attached the submission from the Canadian Gas Association to the Quadrennial Energy Review (QER) process.

  20. American Statistical Association National Science Foundation

    E-Print Network [OSTI]

    Bermúdez, José Luis

    American Statistical Association National Science Foundation U.S. Census Bureau ASA American Statistical Association 732 North Washington Street Alexandria, VA 22314-1943 U.S. government and analysis, statistical methodology and computing, information and behavioral science, and geography

  1. QER- Comment of Geotherman Energy Association (GEA)

    Broader source: Energy.gov [DOE]

    Hi the Geothermal Energy Association would like to submit the attached comments for the 2014 QER process. Thanks,

  2. Some associations of rainfall in Central America

    E-Print Network [OSTI]

    Barnard, Sidney Owen

    1965-01-01T23:59:59.000Z

    on the Pacific coast of Costa Rica and Panama. Generally, high associations are limited to small geographical areas. The Pacific coast areas have higher association than do areas in the mountains or on the Caribbean coast. Associations across the isthmus... activity is not evident in the mountains. Association patterns in southern Costa Rica and southwestern Panama suggest that relatively small terrain features combined with the sea breeze front have great effects on the rainfall variations...

  3. Molecular conformations, interactions, and properties associated...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors Molecular conformations, interactions, and...

  4. Mining Weighted Association Rules without Preassigned Weights

    E-Print Network [OSTI]

    Bai, Fengshan

    Mining Weighted Association Rules without Preassigned Weights Ke Sun and Fengshan Bai Abstract--Association rule mining is a key issue in data mining. However, the classical models ignore the difference between the transactions, and the weighted association rule mining does not work on databases with only binary attributes

  5. Code of Official Conduct Student Government Association

    E-Print Network [OSTI]

    Long, Nicholas

    Code of Official Conduct Student Government Association Stephen F. Austin State University Section, the Student Government Association of Stephen F. Austin State University has adopted this Code of Official Association officials who may be elected, appointed, or employed comply with both the Letter and the Spirit

  6. A report to United Services Automobile Association

    E-Print Network [OSTI]

    A report to United Services Automobile Association (USAA) Submitted by Katie N. Womack Center Driving In Texas Prepared for: United Services Automobile Association (USAA) By: Katie N. Womack Center Services Automobile Association (USAA). The report documents the findings of five tasks undertaken under

  7. association water pollution: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Open Access Theses and Dissertations Summary: ??Understanding the effect of human-induced pollution on the environment is an important precursor to promoting public health and...

  8. Use of growth factors and adhesive ligands to promote connective tissue progenitor colony formation from fresh marrow

    E-Print Network [OSTI]

    Marcantonio, Nicholas A. (Nicholas Alexander)

    2008-01-01T23:59:59.000Z

    The current gold standard for bone graft material is autologous bone, which provides mechanical support, possesses factors that promote bone formation, and contains connective tissue progenitors (CTPs), a heterogeneous ...

  9. The potential for bus rapid transit to promote transit oriented development : an analysis of BRTOD in Ottawa, Brisbane, and Pittsburgh

    E-Print Network [OSTI]

    Judy, Meredith H. (Meredith Hampton)

    2007-01-01T23:59:59.000Z

    This thesis explores the conditions under which bus rapid transit (BRT) can promote transit oriented development (TOD). At a time when cities throughout the U.S. are searching for methods to reduce road congestion and limit ...

  10. Stalled on the Road to the Market: Analysis of Field Experience with a Project to Promote Lighting Efficiency in India

    E-Print Network [OSTI]

    Gadgil, A.J.

    2008-01-01T23:59:59.000Z

    1991. "Energy-Efficient Lighting in Brazil and India:on Energy-Efficient Lighting. Stockholm, Sweden. Katzev,with a Project to Promote Lighting Efficiency in India AJ.

  11. Tension applied through the Dam1 complex promotes microtubule elongation: a direct mechanism for length control in

    E-Print Network [OSTI]

    Davis, Trisha N.

    Tension applied through the Dam1 complex promotes microtubule elongation: a direct mechanism tension to a model of the kinetochore-microtubule interface composed of the yeast Dam1 complex11-13 bound

  12. Molecular analysis of the human SLC13A4 sulfate transporter gene promoter

    SciTech Connect (OSTI)

    Jefferis, J. [Mater Medical Research Institute, South Brisbane, Queensland (Australia)] [Mater Medical Research Institute, South Brisbane, Queensland (Australia); Rakoczy, J. [Mater Medical Research Institute, South Brisbane, Queensland (Australia) [Mater Medical Research Institute, South Brisbane, Queensland (Australia); School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland (Australia); Translational Research Institute, Woolloongabba, Queensland (Australia); Simmons, D.G. [School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland (Australia)] [School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland (Australia); Dawson, P.A., E-mail: paul.dawson@mmri.mater.org.au [Mater Medical Research Institute, South Brisbane, Queensland (Australia); Translational Research Institute, Woolloongabba, Queensland (Australia)

    2013-03-29T23:59:59.000Z

    Highlights: ? Basal promoter activity of SLC13A4 ?57 to ?192 nt upstream of transcription initiation site. ? Human SLC13A4 5?-flanking region has conserved motifs with other placental species. ? Putative NFY, SP1 and KLF7 motifs in SLC13A4 5?-flanking region enhance transcription. -- Abstract: The human solute linked carrier (SLC) 13A4 gene is primarily expressed in the placenta where it is proposed to mediate the transport of nutrient sulfate from mother to fetus. The molecular mechanisms involved in the regulation of SLC13A4 expression remain unknown. To investigate the regulation of SLC13A4 gene expression, we analysed the transcriptional activity of the human SLC13A4 5?-flanking region in the JEG-3 placental cell line using luciferase reporter assays. Basal transcriptional activity was identified in the region ?57 to ?192 nucleotides upstream of the SLC13A4 transcription initiation site. Mutational analysis of the minimal promoter region identified Nuclear factor Y (NFY), Specificity protein 1 (SP1) and Krüppel like factor 7 (KLF7) motifs which conferred positive transcriptional activity, as well as Zinc finger protein of the cerebellum 2 (ZIC2) and helix–loop–helix protein 1 (HEN1) motifs that repressed transcription. The conserved NFY, SP1, KLF7, ZIC2 and HEN1 motifs in the SLC13A4 promoter of placental species but not in non-placental species, suggests a potential role for these putative transcriptional factor binding motifs in the physiological control of SLC13A4 mRNA expression.

  13. Neddylation promotes ubiquitylation and release of Ku from DNA damage sites

    E-Print Network [OSTI]

    Brown, Jessica S.; Lukashchuk, Natalia; Sczaniecka-Clift, Matylda; Britton, Sébastien; le Sage, Carlos; Calsou, Patrick; Beli, Petra; Galanty, Yaron; Jackson, Stephen P.

    2015-04-23T23:59:59.000Z

    observed in BrdU pretreated cells (Figure S1E), implying that in our system, NEDD8 accrual was largely promoted by DSBs rather than other forms of dam- age (Lukas et al., 2003). NEDD8 recruitment did not require the activity of PARP or the DDR kinases ATM... representsthe time taken for neddylation to be completely inhibited in cells by MLN4924 (which occurs within 5 min; Brownell et al., 2010). These data therefore suggested that neddylation is a dynamic modification that occurs and turns over at DSBs, although we...

  14. Magnetohydrodynamic pump with a system for promoting flow of fluid in one direction

    DOE Patents [OSTI]

    Lemoff, Asuncion V. (Union City, CA); Lee, Abraham P. (Irvine, CA)

    2010-07-13T23:59:59.000Z

    A magnetohydrodynamic pump for pumping a fluid. The pump includes a microfluidic channel for channeling the fluid, a MHD electrode/magnet system operatively connected to the microfluidic channel, and a system for promoting flow of the fluid in one direction in the microfluidic channel. The pump has uses in the medical and biotechnology industries for blood-cell-separation equipment, biochemical assays, chemical synthesis, genetic analysis, drug screening, an array of antigen-antibody reactions, combinatorial chemistry, drug testing, medical and biological diagnostics, and combinatorial chemistry. The pump also has uses in electrochromatography, surface micromachining, laser ablation, inkjet printers, and mechanical micromilling.

  15. The Forcing of Mercury Oxidation as a Means of Promoting Low-Cost Capture

    SciTech Connect (OSTI)

    John C. Kramlich; Linda Castiglone

    2003-03-30T23:59:59.000Z

    Trace amounts of mercury are found in all coals. During combustion this mercury is vaporized and can be released to the atmosphere. This has been a cause for concern for a number of years, and has resulted in a determination by the EPA to regulate and control these emissions. Present technology does not, however, provide inexpensive ways to capture or remove mercury from flue gases. The mercury that exits the furnace in the oxidized form (HgCl{sub 2}) is known to much more easily captured in existing wet pollution control equipment (e.g., wet FGD for SO{sub 2}), principally due to its high solubility in water. Until recently, however, nobody knew what caused this oxidation, or how to promote it. Recent DOE-funded research in our group, along with work by others, has identified the gas phase mechanism responsible for this oxidation. The scenario is as follows. In the flame the mercury is quantitatively vaporized as elemental mercury. Also, the chlorine in the fuel is released as HCl. The direct reaction Hg+HCl is, however, far too slow to be of practical consequence in oxidation. The high temperature region does supports a small concentration of atomic chlorine due to disassociation of HCl. As the gases cool (either in the furnace convective passes, in the quench prior to cold gas cleanup, or within a sample probe), the decay in Cl atom is constrained by the slowness of the principal recombination reaction, Cl+Cl+M {yields} Cl{sub 2}+M. This allows chlorine atom to hold a temporary, local superequilibrium concentration. Once the gases drop below about 550 C, the mercury equilibrium shifts to favor HgCl{sub 2} over Hg, and this superequilibrium chlorine atom promotes oxidation via the fast reactions Hg+Cl+M {yields} HgCl+M, HgCl+Cl+M {yields} HgCl{sub 2}+M, and HgCl+Cl{sub 2} {yields} HgCl{sub 2}+Cl. Thus, the high temperature region provides the Cl needed for the reaction, while the quench region allows the Cl to persist and oxidize the mercury in the absence of decomposition reactions that would destroy the HgCl{sub 2}. Promoting mercury oxidation is one means of getting high-efficiency, ''free'' mercury capture when wet gas cleanup systems are already in place. The chemical kinetic model we developed to describe the oxidation process suggests that oxidation can be promoted by introducing trace amounts of H{sub 2} and/or CO within the quench region. The reaction of these fuels leads to free radicals that promote the selective conversion of HCl to Cl, which can then subsequently react with Hg. The work reported here from our Phase I Innovative Concept grant demonstrated this phenomenon, but it also showed that the process must be applied carefully to avoid promoting the recombination of Cl back to HCl. For example, addition of H{sub 2} at too high a temperature is predicted to actually decrease Cl concentrations via Cl+H{sub 2} {yields} HCl+H. At lower temperatures this reaction is slowed due to its activation energy. Thus, within the correct window, the process becomes selective for Cl promotion. Key parameters are the injection temperature of the promoter, the amount of the fuel added. A successful process based on this research will add a powerful tool to the mercury control arsenal. Presently, fractional oxidation in flue gases varies widely, but averages about 50%. The amounts of promoter needed to obtain quantitative oxidation are predicted to be small ({approx}50 ppm). The H{sub 2}/CO could be supplied by conventional natural gas reformer on site, and the low expected fuel concentration would require only a relatively trivial amount of natural gas, even for a large power plant. For example, a 600 MW{sub e} plant would require the order of only 1 MW thermal equivalent of natural gas. If the mercury in the stream approaching a FGD system is highly oxidized, then high captures could be achieved without any additional cost, even for fuels of low chlorine.

  16. Promoting Clean Cars: Case Study of Stockholm and Sweden | Open Energy

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation,Pillar Group BV Jump to:Information Promoting Clean Cars: Case Study of

  17. Chemical inducible promoter used to obtain transgenic plants with a silent marker and organisms and cells and methods of using same for screening for mutations

    DOE Patents [OSTI]

    Zuo, Jianru (New York, NY); Chua, Nam-Hai (Scarsdale, NY)

    2007-06-12T23:59:59.000Z

    Disclosed is a chemically inducible promoter for transforming plants or plant cells with genes which are regulatable by adding the plants or cells to a medium containing an inducer or by removing them from such medium. The promoter is inducible by a glucocorticoid, estrogen or inducer not endogenous to plants. Such promoters may be used with any plant genes that can promote shoot regeneration and development to induce shoot formation in the presence of a glucocorticoid, estrogen or inducer. The promoter may be used with antibiotic or herbicide resistance genes or other genes which are regulatable by the presence or absence of a given inducer. Also presented are organisms or cells comprising a gene wherein the natural promoter of the gene is disrupted and the gene is placed under the control of a transgenic inducible promoter. These organisms and cells and their progeny are useful for screening for conditional gain of function and loss of function mutations.

  18. Thymosin beta-4 promotes mesenchymal stem cell proliferation via an interleukin-8-dependent mechanism

    SciTech Connect (OSTI)

    Jeon, Byung-Joon [Department of Plastic and Reconstructive Surgery, Korea University Medical Center, Gojan 1-dong, Danwon-gu, Ansan-si, Gyeonggi-do 425-707 (Korea, Republic of); Yang, Yoolhee; Kyung Shim, Su [Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710 (Korea, Republic of); Yang, Heung-Mo [Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710 (Korea, Republic of); Cho, Daeho, E-mail: cdhkor@sookmyung.ac.kr [Department of Life Science, Sookmyung Women's University, Hyochangwon-gil 52, Yongsan-gu, Seoul 140-742 (Korea, Republic of); Ik Bang, Sa, E-mail: si55.bang@samsung.com [Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710 (Korea, Republic of)

    2013-10-15T23:59:59.000Z

    Mesenchymal stem cells (MSCs) hold great promise for the field of tissue regeneration. Because only a limited number of MSCs can be obtained from each donor site, it is important to establish standard methods for MSC expansion using growth and trophic factors. Thymosin ?4 (T?4) is a novel trophic factor that has antimicrobial effects and the potential to promote tissue repair. T?4 is a ubiquitous, naturally-occurring peptide in the wound bed. Therefore, the relationship between T?4 and MSCs, especially adjacent adipose tissue-derived stem cells (ASCs), merits consideration. Exogenous T?4 treatment enhanced the proliferation of human ASCs, resulting in prominent nuclear localization of PCNA immunoreactivity. In addition, exogenous T?4 also increased IL-8 secretion and blocking of IL-8 with neutralizing antibodies decreased T?4-induced ASC proliferation, suggesting that IL-8 is a critical mediator of T?4-enhanced proliferation. Moreover, T?4 activated phosphorylation of ERK1/2 and increased the nuclear translocation of NF-?B. These observation provide that T?4 promotes the expansion of human ASCs via an IL-8-dependent mechanism that involves the ERK and NF-?B pathways. Therefore, T?4 could be used as a tool for MSC expansion in cell therapeutics. - Highlights: • This is fundamental information required to correlate T?4 with MSC expansion. • MSC expansion by T?4 is involved in enhancement of IL-8 and ERK/NF-?B pathway. • T?4 could be used as a tool for MSC expansion in cell therapeutics.

  19. Ethanol Steam Reforming on Co/CeO2: The Effect of ZnO Promoter

    SciTech Connect (OSTI)

    Davidson, Stephen; Sun, Junming; Wang, Yong

    2013-12-02T23:59:59.000Z

    A series of ZnO promoted Co/CeO2 catalysts were synthesized and characterized using XRD, TEM, H2-TPR, CO chemisorption, O2-TPO, IR-Py, and CO2-TPD. The effects of ZnO on the catalytic performances of Co/CeO2 were studied in ethanol steam reforming. It was found that the addition of ZnO facilitated the oxidation of Co0 via enhanced oxygen mobility of the CeO2 support which decreased the activity of Co/CeO2 in C–C bond cleavage of ethanol. 3 wt% ZnO promoted Co/CeO2 exhibited minimum CO and CH4 selectivity and maximum CO2 selectivity. This resulted from the combined effects of the following factors with increasing ZnO loading: (1) enhanced oxygen mobility of CeO2 facilitated the oxidation of CHx and CO to form CO2; (2) increased ZnO coverage on CeO2 surface reduced the interaction between CHx/CO and Co/CeO2; and (3) suppressed CO adsorption on Co0 reduced CO oxidation rate to form CO2. In addition, the addition of ZnO also modified the surface acidity and basicity of CeO2, which consequently affected the C2–C4 product distributions.

  20. Selective methane oxidation over promoted oxide catalysts. Topical report, September 8, 1992--September 7, 1996

    SciTech Connect (OSTI)

    Klier, K.; Herman, R.G.

    1996-12-31T23:59:59.000Z

    The objective of this research was to selectively oxidize methane to C{sub 2} hydrocarbons and to oxygenates, in particular formaldehyde and methanol, in high space time yields using air at the oxidant under milder reaction conditions that heretofore employed over industrially practical oxide catalysts. The research carried out under this US DOE-METC contract was divided into the following three tasks: Task 1, maximizing selective methane oxidation to C{sub 2}{sup +} products over promoted SrO/La{sub 2}O{sub 3} catalysts; Task 2, selective methane oxidation to oxygenates; and Task 3, catalyst characterization and optimization. Principal accomplishments include the following: the 1 wt% SO{sub 4}{sup 2{minus}}/SrO/La{sub 2}O{sub 3} promoted catalyst developed here produced over 2 kg of C{sub 2} hydrocarbons/kg catalyst/hr at 550 C; V{sub 2}O{sub 5}/SiO{sub 2} catalysts have been prepared that produce up to 1.5 kg formaldehyde/kg catalyst/hr at 630 C with low CO{sub 2} selectivities; and a novel dual bed catalyst system has been designed and utilized to produce over 100 g methanol/kg catalyst/hr at 600 C with the presence of steam in the reactant mixture.

  1. Fibronectin promotes differentiation of neural crest progenitors endowed with smooth muscle cell potential

    SciTech Connect (OSTI)

    Costa-Silva, Bruno [Departamento de Biologia Celular, Embriologia e Genetica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Programa de Pos-graduacao em Neurociencias, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Coelho da Costa, Meline; Melo, Fernanda Rosene; Neves, Cynara Mendes [Departamento de Biologia Celular, Embriologia e Genetica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Alvarez-Silva, Marcio [Departamento de Biologia Celular, Embriologia e Genetica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Programa de Pos-graduacao em Neurociencias, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Calloni, Giordano Wosgrau [Departamento de Biologia Celular, Embriologia e Genetica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Programa de Pos-graduacao em Ciencias Morfologicas, Instituto de Ciencias da Saude, Universidade Federal do Rio de Janeiro - Ilha do Fundao, 21949-590, Rio de Janeiro, R.J. (Brazil); Trentin, Andrea Goncalves [Departamento de Biologia Celular, Embriologia e Genetica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil); Programa de Pos-graduacao em Neurociencias, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Campus Universitario - Trindade, 88040-900, Florianopolis, S.C. (Brazil)], E-mail: atrentin@ccb.ufsc.br

    2009-04-01T23:59:59.000Z

    The neural crest (NC) is a model system used to investigate multipotency during vertebrate development. Environmental factors control NC cell fate decisions. Despite the well-known influence of extracellular matrix molecules in NC cell migration, the issue of whether they also influence NC cell differentiation has not been addressed at the single cell level. By analyzing mass and clonal cultures of mouse cephalic and quail trunk NC cells, we show for the first time that fibronectin (FN) promotes differentiation into the smooth muscle cell phenotype without affecting differentiation into glia, neurons, and melanocytes. Time course analysis indicated that the FN-induced effect was not related to massive cell death or proliferation of smooth muscle cells. Finally, by comparing clonal cultures of quail trunk NC cells grown on FN and collagen type IV (CLIV), we found that FN strongly increased both NC cell survival and the proportion of unipotent and oligopotent NC progenitors endowed with smooth muscle potential. In contrast, melanocytic progenitors were prominent in clonogenic NC cells grown on CLIV. Taken together, these results show that FN promotes NC cell differentiation along the smooth muscle lineage, and therefore plays an important role in fate decisions of NC progenitor cells.

  2. Energy Department, Northwest Food Processors Association Set...

    Office of Environmental Management (EM)

    Food Processors Association today set ambitious goals to reduce energy use and carbon emissions in the industrial sector. DOE Industrial Technologies Program Manager Douglas Kaempf...

  3. Sandia National Laboratories: lowering costs associated with...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    costs associated with geothermal energy production Sandia and Atlas-Copco Secoroc Advance to Phase 2 in Their Geothermal Energy Project On July 31, 2013, in Energy, Geothermal,...

  4. Conventional Energy Forum & Associated Vertical Business Development...

    Office of Environmental Management (EM)

    & Casino The Office of Indian Energy Tribal Leader Energy Forum on "Conventional Energy (Oil, Gas, and Coal) Forum & Associated Vertical Business Development: Best Practices in...

  5. Sponsors of CIEEDAC: Environment Canada, Natural Resources Canada, Aluminium Association of Canada, Automobile Parts Manufacturing Association, Brewers Association of Canada, Canadian Fertilizer Institute, Canadian Foundry Association, Canadian Fuels

    E-Print Network [OSTI]

    Sponsors of CIEEDAC: Environment Canada, Natural Resources Canada, Aluminium Association) ........................................................................................ 3 1.3.2 Medium Term (25 years ................................................................................................... 14 3.2.2 Medium Term

  6. Valley Electric Association- Solar Water Heating Program

    Broader source: Energy.gov [DOE]

    Valley Electric Association (VEA), a nonprofit member owned cooperative, developed the domestic solar water heating program to encourage energy efficiency at the request of the membership. VEA...

  7. Stearns Electric Association- Energy Efficiency Loan Program

    Broader source: Energy.gov [DOE]

    Stearns Electric Association, through a program offered by Rural Utilities Services, offers its members low-interest Energy Resource Conservation (ERC) loans. The complete cost of making approved...

  8. Voluntary Codes of Practice: Non-Governmental Institutions for Promoting Environmental Management by Firms

    E-Print Network [OSTI]

    Nash, Jennifer

    2002-08-26T23:59:59.000Z

    This paper is divided into three parts. The first part explores the question of why certain trade associations have developed environmental codes for their members. The second part considers the effectiveness of trade ...

  9. Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

    E-Print Network [OSTI]

    Gao, Qing

    Alterations in DNA methylation have been associated with genome-wide hypomethylation and regional de novo methylation in numerous cancers. De novo methylation is mediated by the de novo methyltransferases Dnmt3a and 3b, ...

  10. Inflammation and Infection Do Not Promote Arterial Aging and Cardiovascular Disease Risk Factors among

    E-Print Network [OSTI]

    Gurven, Michael

    Departamento de Medicina, Universidad Mayor de San Simo´n, Cochabamba, Bolivia, 5 Andrus Gerontology Center associations of ABI and BP with biomarkers of energy balance and metabolism and of inflammation and infection

  11. Student Association Executive Memo 10 October 2013

    E-Print Network [OSTI]

    Reynolds, Albert C.

    , 2013, Student Association Senate passed a series of revisions to our Financial Allocations Guidelines Association. These revisions, we believe, will help our Financial Allocations Process to be fairer, more happy to answer them. · Article II, Section A, Subsection 5 and point a is added: "The submitted bills

  12. Roadmap: Associate of Arts Regional College

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Associate of Arts [RE-AA-AA] Regional College Catalog Year: 2012-2013 Page 1 of 2 | Last Updated: 12-Mar-12/LNHD This roadmap is a recommended semester-by-semester plan of study for this major GPA Overall GPA 61 2.000 2.000 #12;Roadmap: Associate of Arts [RE-AA-AA] Regional College Catalog Year

  13. Roadmap: Associate of Arts Regional College

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Associate of Arts [RE-AA-AA] Regional College Catalog Year: 2013-2014 Page 1 of 2 | Last Updated: 27-Feb-13/LNHD This roadmap is a recommended semester-by-semester plan of study for this major.000 #12;Roadmap: Associate of Arts [RE-AA-AA] Regional College Catalog Year: 2013-2014 Page 2 of 2 | Last

  14. Roadmap: Associate of Science Regional College

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Associate of Science [RE-AS-AS] Regional College Catalog Year: 2013-2014 Page 1 of 2 | Last Updated: 27-Feb-13/LNHD This roadmap is a recommended semester-by-semester plan of study.000 #12;Roadmap: Associate of Science [RE-AS-AS] Regional College Catalog Year: 2013-2014 Page 2 of 2

  15. Roadmap: Associate of Science Regional College

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Associate of Science [RE-AS-AS] Regional College Catalog Year: 2012-2013 Page 1 of 2 | Last Updated: 12-Mar-12/LNHD This roadmap is a recommended semester-by-semester plan of study GPA Overall GPA 61 2.000 2.000 #12;Roadmap: Associate of Science [RE-AS-AS] Regional College Catalog

  16. The Japan Scotland Association Scholarship 1. Objective

    E-Print Network [OSTI]

    Little, Tony

    The Japan Scotland Association Scholarship 1. Objective To assist Japanese students at Master society. 2. Background This scholarship scheme was set up to help improve links between Japan and Scotland (one of the aims of the Japan Scotland Association). Planned to commence September 2013. 3. Number

  17. Research Associate Position Defense Analysis Department

    E-Print Network [OSTI]

    in analyzing social network data as well as geospatial, temporal, and standard statistical analysis of largeResearch Associate Position Defense Analysis Department Naval Postgraduate School, Monterey, CA Research Associate The Department of Defense Analysis is home to the CORE (Common Operational Research

  18. GREEN FUNCTIONS ASSOCIATED TO COMPLEX REFLECTION GROUPS

    E-Print Network [OSTI]

    Shoj, Toshiaki

    GREEN FUNCTIONS ASSOCIATED TO COMPLEX REFLECTION GROUPS TOSHIAKI SHOJI Department of Mathematics Science University of Tokyo Noda, Chiba 278­8510, Japan Abstract. Green functions of classical groups this, we define Green functions associated to complex reflection groups G(e, 1, n), and study

  19. Organizational Chart AssociateVice President

    E-Print Network [OSTI]

    Plotkin, Joshua B.

    Organizational Chart AssociateVice President Michelle H. Brown-Nevers, Ed.D. Associate Vice PennPlan online content n Media Liaison n Social Media #12;Organizational Chart Michael Merritt;Organizational Chart Sharon Pepe Senior Director Credit Services Josephine Delaney Manager Collections Assistant

  20. Assistant or Associate Professor in Sedimentology

    E-Print Network [OSTI]

    Assistant or Associate Professor in Sedimentology The Department of Earth Sciences (DES), Mineral for a tenure-track Assistant or Associate Professor position in Sedimentology to begin in July 2015. We seek an innovative individual with excellent teaching and research skills in sedimentology. Expertise in Precambrian

  1. Mechanism of Methane Chemical Looping Combustion with Hematite Promoted with CeO2

    SciTech Connect (OSTI)

    Miller, Duane D.; Siriwardane, Ranjani

    2013-08-01T23:59:59.000Z

    Chemical looping combustion (CLC) is a promising technology for fossil fuel combustion that produces sequestration-ready CO{sub 2} stream, reducing the energy penalty of CO{sub 2} separation from flue gases. An effective oxygen carrier for CLC will readily react with the fuel gas and will be reoxidized upon contact with oxygen. This study investigated the development of a CeO{sub 2}-promoted Fe{sub 2}O{sub 3}?hematite oxygen carrier suitable for the methane CLC process. Composition of CeO{sub 2} is between 5 and 25 wt % and is lower than what is generally used for supports in Fe{sub 2}O{sub 3} carrier preparations. The incorporation of CeO{sub 2} to the natural ore hematite strongly modifies the reduction behavior in comparison to that of CeO{sub 2} and hematite alone. Temperature-programmed reaction studies revealed that the addition of even 5 wt % CeO{sub 2} enhances the reaction capacity of the Fe{sub 2}O{sub 3} oxygen carrier by promoting the decomposition and partial oxidation of methane. Fixed-bed reactor data showed that the 5 wt % cerium oxides with 95 wt % iron oxide produce 2 times as much carbon dioxide in comparison to the sum of carbon dioxide produced when the oxides were tested separately. This effect is likely due to the reaction of CeO{sub 2} with methane forming intermediates, which are reactive for extracting oxygen from Fe{sub 2}O{sub 3} at a considerably faster rate than the rate of the direct reaction of Fe{sub 2}O{sub 3} with methane. These studies reveal that 5 wt % CeO{sub 2}/Fe{sub 2}O{sub 3} gives stable conversions over 15 reduction/oxidation cycles. Lab-scale reactor studies (pulsed mode) suggest the methane reacts initially with CeO{sub 2} lattice oxygen to form partial oxidation products (CO + H{sub 2}), which continue to react with oxygen from neighboring Fe{sub 2}O{sub 3}, leading to its complete oxidation to form CO{sub 2}. The reduced cerium oxide promotes the methane decomposition reaction to form C + H{sub 2}, which continue to react with Fe{sub 2}O{sub 3}/Fe{sub 3}O{sub 4} to form CO/CO{sub 2} and H{sub 2}O. This mechanism is supported by the characterization studies, which also suggest that the formation of carbonaceous intermediates may affect the reaction rate and selectivity of the oxygen carrier.

  2. Deactivation and regeneration of a promoted transition-metal-zeolite catalyst

    SciTech Connect (OSTI)

    Pennline, H.W.; Pollack, S.S.

    1986-03-01T23:59:59.000Z

    The regeneration of a promoted transition-metal-zeolite catalyst that had been used to convert synthesis gas to gasoline-range hydrocarbons was investigated in a mixed reactor system. Carbonaceous deposits were found on the catalyst-a coprecipitated cobalt-thoria admixed with ZSM-5 zeolite-after it has been subjected to low hydrogen to carbon monoxide ratio synthesis gas at the processing conditions. Oxidative regenerations did not succeed in returning the catalyst to its initial synthesis activity. X-ray diffraction analysis of the used and regenerated catalyst samples suggested that sintering of the cobalt occurred. The crystallite size of the Co/sub 3/O/sub 4/ formed after regeneration was inversely related to the synthesis gas conversion after reduction of the Co/sub 3/O/sub 4/ to the metal.

  3. Hydrogenation of Carbon Dioxide by Water: Alkali-Promoted Synthesis of Formate

    SciTech Connect (OSTI)

    Hrbek, J.; Hoffmann, F.M.; Yang, Y.; Paul, J.; White, M.G.

    2010-07-15T23:59:59.000Z

    Conversion of carbon dioxide utilizing protons from water decomposition is likely to provide a sustainable source of fuels and chemicals in the future. We present here a time-evolved infrared reflection absorption spectroscopy (IRAS) and temperature-programmed desorption (TPD) study of the reaction of CO{sub 2} + H{sub 2}O in thin potassium layers. Reaction at temperatures below 200 K results in the hydrogenation of carbon dioxide to potassium formate. Thermal stability of the formate, together with its sequential transformation to oxalate and to carbonate, is monitored and discussed. The data of this model study suggest a dual promoter mechanism of the potassium: the activation of CO{sub 2} and the dissociation of water. Reaction at temperatures above 200 K, in contrast, is characterized by the absence of formate and the direct reaction of CO{sub 2} to oxalate, due to a drastic reduction of the sticking coefficient of water at higher temperatures.

  4. Fischer-Tropsch activity for non-promoted cobalt-on-alumina catalysts

    DOE Patents [OSTI]

    Singleton, Alan H. (Baden, PA); Oukaci, Rachid (Gibsonia, PA); Goodwin, James G. (Gibsonia, PA)

    2001-01-01T23:59:59.000Z

    Cobalt catalysts, and processes employing these inventive catalysts, for hydrocarbon synthesis. The inventive catalyst comprises cobalt on an alumina support and is not promoted with any noble or near noble metals. In one aspect of the invention, the alumina support preferably includes a dopant in an amount effective for increasing the activity of the inventive catalyst. The dopant is preferably a titanium dopant. In another aspect of the invention, the cobalt catalyst is preferably reduced in the presence of hydrogen at a water vapor partial pressure effective to increase the activity of the cobalt catalyst for hydrocarbon synthesis. The water vapor partial pressure is preferably in the range of from 0 to about 0.1 atmospheres.

  5. Hydrocracking and hydroisomerization of long-chain alkanes and polyolefins over metal-promoted anion-modified transition metal oxides

    SciTech Connect (OSTI)

    Venkatesh, Koppampatti R.; Hu, Jianli; Tierney, John W.; Wender, Irving

    1996-12-01T23:59:59.000Z

    A method is described for cracking a feedstock by contacting the feedstock with a metal-promoted anion-modified metal oxide catalyst in the presence of hydrogen gas. The metal oxide of the catalyst is one or more of ZrO{sub 2}, HfO{sub 2}, TiO{sub 2} and SnO{sub 2}, and the feedstock is principally chains of at least 20 carbon atoms. The metal-promoted anion-modified metal oxide catalyst contains one or more of Pt, Ni, Pd, Rh, Ir, Ru, (Mn and Fe) or mixtures of them present between about 0.2% to about 15% by weight of the catalyst. The metal-promoted anion-modified metal oxide catalyst contains one or more of SO{sub 4}, WO{sub 3}, or mixtures of them present between about 0.5% to about 20% by weight of the catalyst.

  6. Michigan State University Alumni Association MICHIGAN STATE UNIVERSITY

    E-Print Network [OSTI]

    Michigan State University Alumni Association Bylaws #12;2 MICHIGAN STATE UNIVERSITY ALUMNI of the organization shall be the Michigan State University Alumni Association (hereinafter, the "Association"). Section 2 Mission Statement The Michigan State University Alumni Association supports and enhances

  7. Genome-wide association study identifies three loci associated with melanoma risk

    E-Print Network [OSTI]

    Pennsylvania, University of

    Genome-wide association study identifies three loci associated with melanoma risk D Timothy Bishop1-wide association study of melanoma conducted by the GenoMEL consortium based on 317K tagging SNPs for 1 and cutaneous sun sensitivity, well-recognized melanoma risk factors. Common variants within the 9p21 locus have

  8. association cardiomiopatia hipertrofica: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Categories Designated substances Sustainable building materials 12;Brookhaven Science Associates Drivers for Purchasing of Green 9 TUCKER BALCH ASSOCIATE PROFESSOR...

  9. Fact Sheet: DOE/National Association of Regulatory Utility Commissione...

    Office of Environmental Management (EM)

    DOENational Association of Regulatory Utility Commissioners Natural Gas Infrastructure Modernization Partnership Fact Sheet: DOENational Association of Regulatory Utility...

  10. No Effect of the Transforming Growth Factor {beta}1 Promoter Polymorphism C-509T on TGFB1 Gene Expression, Protein Secretion, or Cellular Radiosensitivity

    SciTech Connect (OSTI)

    Reuther, Sebastian; Metzke, Elisabeth [Laboratory of Radiobiology and Experimental Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany)] [Laboratory of Radiobiology and Experimental Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany); Bonin, Michael [Department of Medical Genetics, University of Tuebingen (Germany)] [Department of Medical Genetics, University of Tuebingen (Germany); Petersen, Cordula [Clinic of Radiotherapy and Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany)] [Clinic of Radiotherapy and Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany); Dikomey, Ekkehard, E-mail: dikomey@uke.de [Laboratory of Radiobiology and Experimental Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany)] [Laboratory of Radiobiology and Experimental Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany); Raabe, Annette [Laboratory of Radiobiology and Experimental Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany)] [Laboratory of Radiobiology and Experimental Radiooncology, University Hospital Hamburg-Eppendorf, Hamburg (Germany)

    2013-02-01T23:59:59.000Z

    Purpose: To study whether the promoter polymorphism (C-509T) affects transforming growth factor {beta}1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocytes and fibroblasts. Methods and Materials: Experiments were performed with lymphocytes taken either from 124 breast cancer patients or 59 pairs of normal monozygotic twins. We used 15 normal human primary fibroblast strains as controls. The C-509T genotype was determined by polymerase chain reaction-restriction fragment length polymorphism or TaqMan single nucleotide polymorphism (SNP) genotyping assay. The cellular radiosensitivity of lymphocytes was measured by G0/1 assay and that of fibroblasts by colony assay. The amount of extracellular TGFB1 protein was determined by enzyme-linked immunosorbent assay, and TGFB1 expression was assessed via microarray analysis or reverse transcription-polymerase chain reaction. Results: The C-509T genotype was found not to be associated with cellular radiosensitivity, neither for lymphocytes (breast cancer patients, P=.811; healthy donors, P=.181) nor for fibroblasts (P=.589). Both TGFB1 expression and TGFB1 protein secretion showed considerable variation, which, however, did not depend on the C-509T genotype (protein secretion: P=.879; gene expression: lymphocytes, P=.134, fibroblasts, P=.605). There was also no general correlation between TGFB1 expression and cellular radiosensitivity (lymphocytes, P=.632; fibroblasts, P=.573). Conclusion: Our data indicate that any association between the SNP C-509T of TGFB1 and risk of normal tissue toxicity cannot be ascribed to a functional consequence of this SNP, either on the level of gene expression, protein secretion, or cellular radiosensitivity.

  11. American Statistical Association Names Fellows for 2010 ALEXANDRIA VA (PRWEB) MAY 20, 2010 The American Statistical Association (ASA), the

    E-Print Network [OSTI]

    Ponce, V. Miguel

    American Statistical Association Names Fellows for 2010 ALEXANDRIA VA (PRWEB) MAY 20, 2010 ­ The American Statistical Association (ASA), the nation's preeminent professional statistical society, today the American Statistical Association The American Statistical Association (ASA), a scientific and educational

  12. Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells

    E-Print Network [OSTI]

    Gupta, Piyush

    Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally ...

  13. Oklahoma Indian Gaming Association Annual Conference

    Broader source: Energy.gov [DOE]

    Join more than 2,500 industry professionals from all over the country at the 2012 Oklahoma Indian Gaming Association (OIGA) Conference and Trade Show specifically devoted to all aspects of the...

  14. Society Associates Marjorie A. Couch and

    E-Print Network [OSTI]

    Napier, Terrence

    . Murto, Jr. '39 1940 Society Associates Carol and Norman Hammer '40 ++ Norman L. Morse '40 Beatrice and F and Andrew K. Morris '50 ++ Mary and Michael J. Murray '50 Lenore C. and Ferris M. Saydah '50 '90P ++ Herbert

  15. Andrew Garrison Curriculum Vitae Associate Professor

    E-Print Network [OSTI]

    Johnston, Daniel

    Andrew Garrison ­ Curriculum Vitae Associate Professor B.A., Communication/Political Science of the stories of Gurney Norman. Broadcast on PBS begins August, 2000. Winner, First Annual Henry Hampton Award

  16. Association For Neurologically Impaired Children Web Newsletter

    E-Print Network [OSTI]

    Kraus, Nina

    Association For Neurologically Impaired Children Web Newsletter www.afniconline.org Year 2005 of life, such as home, social settings, school or work. #12;Year 2005 in review pt. 1 Web Newsletter page

  17. Assistant/Associate Professor Forage Systems

    E-Print Network [OSTI]

    Veiga, Pedro Manuel Barbosa

    Assistant/Associate Professor Forage Systems Department of Plant and Soil Sciences Division of Agricultural Sciences and Natural Resources Oklahoma State University ­ Stillwater, Oklahoma POSITION DESCRIPTION The Department of Plant and Soil Sciences, Oklahoma State University is seeking applicants

  18. QER- Comment of National Propane Gas Association

    Broader source: Energy.gov [DOE]

    Ladies and Gentlemen: Please find attached the QER comments of the National Propane Gas Association. Please feel to contact us if we can provide further information. Thank you for your attention to our submission.

  19. Telomere-associated proteins in Arabidopsis thaliana

    E-Print Network [OSTI]

    Surovtseva, Yulia V.

    2009-05-15T23:59:59.000Z

    . Telomere functions are mediated by a large array of telomere-associated proteins. Mutations in telomere-related genes cause immediate telomere dysfunction, activation of DNA damage response, and accumulation of end-to-end chromosome fusions. In addition...

  20. Edmund J. Synakowski Fusion Power Associates Meeting

    E-Print Network [OSTI]

    Edmund J. Synakowski Fusion Power Associates Meeting September 27 - 28, 2006 The LLNL Fusion Energy Fusion Energy Program: leadership roles in both MFE and IFE, buoyed by ITER, NIF science, and LLNL

  1. Complete regression of melanoma associated with vitiligo

    E-Print Network [OSTI]

    Piqué-Duran, Enric; Palacios-Llopis, Santiago; Martínez-Martín, MªSol; Pérez-Cejudo, Juan A

    2011-01-01T23:59:59.000Z

    D, Hamilton R, Halpern AC. Melanoma of unknown primary site.from an unknown primary melanoma. J Clin Oncol 2008; 26:associated with metastatic melanoma of an unknown origin.

  2. Costs Associated With Propane Vehicle Fueling Infrastructure

    SciTech Connect (OSTI)

    Smith, M.; Gonzales, J.

    2014-08-01T23:59:59.000Z

    This document is designed to help fleets understand the cost factors associated with propane vehicle fueling infrastructure. It provides an overview of the equipment and processes necessary to develop a propane fueling station and offers estimated cost ranges.

  3. Sequentially Triggered Star Formation in OB Associations

    E-Print Network [OSTI]

    Thomas Preibisch; Hans Zinnecker

    2006-10-27T23:59:59.000Z

    We discuss observational evidence for sequential and triggered star formation in OB associations. We first review the star formation process in the Scorpius-Centaurus OB association, the nearest OB association to the Sun, where several recent extensive studies have allowed us to reconstruct the star formation history in a rather detailed way. We then compare the observational results with those obtained for other OB associations and with recent models of rapid cloud and star formation in the turbulent interstellar medium. We conclude that the formation of whole OB subgroups (each consisting of several thousand stars) requires large-scale triggering mechanisms such as shocks from expanding wind and supernova driven superbubbles surrounding older subgroups. Other triggering mechanisms, like radiatively driven implosion of globules, also operate, but seem to be secondary processes, forming only small stellar groups rather than whole OB subgroups with thousands of stars.

  4. Bhagu Chahar Associate Professor, Department of

    E-Print Network [OSTI]

    Chahar, B. R.

    Bhagu Chahar Associate Professor, Department of Civil Engineering, Indian Institute of Technology trapezoidal canal sections B. R. Chahar PhD, FISH, MIE, MIWRS, MIAH and S. Basu MTech Optimal design equations

  5. Sponsors of CIEEDAC: Environment Canada, Natural Resources Canada, Aluminium Association of Canada, Automobile Parts Manufacturing Association, Brewers Association of Canada, Canadian Energy Pipeline Association, Canadian Fertilizer Institute,

    E-Print Network [OSTI]

    Sponsors of CIEEDAC: Environment Canada, Natural Resources Canada, Aluminium Association of Canada)........................................................................................ 3 1.3.2 Medium Term (2-5 years ................................................................................................... 14 3.2.2 Medium Term

  6. Society Associate Percival L. Hallowell '18* ++

    E-Print Network [OSTI]

    Napier, Terrence

    C. Lucks '47 ++ Ruth and Myron Pomerantz '47 Barbara and Frederick N. Spencer '47 ++ Ora PP '11GP Joanie M. and Murray H. Goodman '48 '88H June W. and Leon C. Holt '48 ++ Society Associates

  7. Architecture Associated with Veterinary Education in Edinburgh 

    E-Print Network [OSTI]

    Warwick, Colin M; Macdonald, Alastair A

    The Royal (Dick) School of Veterinary Studies, (the Dick Vet), has been part of Edinburgh's history for over 10 years. However, it is not generally realised that the city has had a longer association with veterinary medicine, ...

  8. Ris-R-1579(EN) Association Euratom -

    E-Print Network [OSTI]

    : Association Euratom - Risø National Laboratory Annual Progress Report 2005 Department: Optics and Plasma Research Department Risø-R-1579(EN) November 2006 ISSN 0106-2840 ISSN 1901-3922 ISSN 1396-3449 ISBN 87

  9. Fusion Power Associates Fusion Energy Sciences Program

    E-Print Network [OSTI]

    Fusion Power Associates Fusion Energy Sciences Program www.ofes.fusion.doe.gov U.S. Department for ITER Decision Making (IAEA, November 8-9, 2004) Delegations from China, European Union, Japan

  10. EV Community Readiness projects: American Lung Association of...

    Broader source: Energy.gov (indexed) [DOE]

    TN) - Promote PEVs and educate the public through a variety of events, such as the Better Living Show, community events and at the science museum. - Spread the word on PEV tourism...

  11. Auto-associative nanoelectronic neural network

    SciTech Connect (OSTI)

    Nogueira, C. P. S. M.; Guimarães, J. G. [Departamento de Engenharia Elétrica - Laboratório de Dispositivos e Circuito Integrado, Universidade de Brasília, CP 4386, CEP 70904-970 Brasília DF (Brazil)

    2014-05-15T23:59:59.000Z

    In this paper, an auto-associative neural network using single-electron tunneling (SET) devices is proposed and simulated at low temperature. The nanoelectronic auto-associative network is able to converge to a stable state, previously stored during training. The recognition of the pattern involves decreasing the energy of the input state until it achieves a point of local minimum energy, which corresponds to one of the stored patterns.

  12. Associative memory in phasing neuron networks

    SciTech Connect (OSTI)

    Nair, Niketh S [ORNL; Bochove, Erik J. [United States Air Force Research Laboratory, Kirtland Air Force Base; Braiman, Yehuda [ORNL

    2014-01-01T23:59:59.000Z

    We studied pattern formation in a network of coupled Hindmarsh-Rose model neurons and introduced a new model for associative memory retrieval using networks of Kuramoto oscillators. Hindmarsh-Rose Neural Networks can exhibit a rich set of collective dynamics that can be controlled by their connectivity. Specifically, we showed an instance of Hebb's rule where spiking was correlated with network topology. Based on this, we presented a simple model of associative memory in coupled phase oscillators.

  13. Supplemental Material for Severson et al. The axial element protein HTP-3 promotes cohesin loading and meiotic axis

    E-Print Network [OSTI]

    Meyer, Barbara

    Supplemental Material for Severson et al. The axial element protein HTP-3 promotes cohesin loading ......................................................................................... 7 Disrupting REC-8, HTP-3, or HTP-1/2 function reduces the lethality of spo-11(me44) mutants ....................................................................................... 13 The htp-3 deletion allele tm3655 phenocopies htp-3(y428). Supplemental Figure 8

  14. Sparsity-Promoting Optimal Control for a Class of Distributed Systems Makan Fardad, Fu Lin, and Mihailo R. Jovanovic

    E-Print Network [OSTI]

    Jovanovic, Mihailo

    Sparsity-Promoting Optimal Control for a Class of Distributed Systems Makan Fardad, Fu Lin, and Mihailo R. Jovanovi´c Abstract-- We consider a linear quadratic optimal control problem with an additional [1], where it was shown that optimal controllers for spatially-invariant systems, although

  15. Nutrition and Cancer, 62(5), 567573 Authors' version Freeze-Dried Ham Promotes Azoxymethane-Induced

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Nutrition and Cancer, 62(5), 567­573 Authors' version Freeze-Dried Ham Promotes Azoxymethane, INRA, 180 Tournefeuille, F-31931 Toulouse, France Abstract Processed and red meat consumption with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free

  16. Rev-erb beta regulates the Srebp-1c promoter and mRNA expression in skeletal muscle cells

    SciTech Connect (OSTI)

    Ramakrishnan, Sathiya N.; Lau, Patrick; Crowther, Lisa M. [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)] [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia); Cleasby, Mark E. [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia)] [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia); Millard, Susan; Leong, Gary M. [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)] [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia); Cooney, Gregory J. [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia)] [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia); Muscat, George E.O., E-mail: g.muscat@imb.uq.edu.au [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)

    2009-10-30T23:59:59.000Z

    The nuclear hormone receptor, Rev-erb beta operates as a transcriptional silencer. We previously demonstrated that exogenous expression of Rev-erb{beta}{Delta}E in skeletal muscle cells increased Srebp-1c mRNA expression. We validated these in vitro observations by injection of an expression vector driving Rev-erb{beta}{Delta}E expression into mouse tibialis muscle that resulted in increased Srebp-1c mRNA expression. Paradoxically, Rev-erb{beta} siRNA expression in skeletal muscle cells repressed Srebp-1c expression, and indicated that Rev-erb{beta} expression was necessary for Srebp-1c expression. ChIP analysis demonstrated that Rev-erb{beta} was recruited to the Srebp-1c promoter. Moreover, Rev-erb{beta} trans-activated the Srebp-1c promoter, in contrast, Rev-erb{beta} efficiently repressed the Rev-erb{alpha} promoter, a previously characterized target gene. Finally, treatment with the Rev-erb agonist (hemin) (i) increased the trans-activation of the Srebp-1c promoter by Rev-erb{beta}; and (ii) increased Rev-erb{beta} and Srebp-1c mRNA expression. These data suggest that Rev-erb{beta} has the potential to activate gene expression, and is a positive regulator of Srebp-1c, a regulator of lipogenesis.

  17. Characterization of the PvdS-regulated promoter motif in Pseudomonas syringae pv. tomato DC3000 reveals

    E-Print Network [OSTI]

    Myers, Chris

    Characterization of the PvdS-regulated promoter motif in Pseudomonas syringae pv. tomato DC3000S, a group IV sigma factor encoded by Pseudomonas syringae pv. tomato DC3000 (DC3000), a plant pathogen, 2002; Potvin et al., 2008). The model plant pathogen Pseudomonas syringae pv. tomato DC3000 (DC3000

  18. Genetic Inactivation of ERK1 and ERK2 in Chondrocytes Promotes Bone Growth and Enlarges the Spinal Canal

    E-Print Network [OSTI]

    Genetic Inactivation of ERK1 and ERK2 in Chondrocytes Promotes Bone Growth and Enlarges the Spinal dysplasia. In mouse models of achondroplasia, recent studies have implicated the ERK MAPK pathway, a pathway and ERK MAPK signaling in chondrocytes also causes premature synchondrosis closure in the cranial base

  19. GCMS SPME profiling of rhizobacterial volatiles reveals prospective inducers of growth promotion and induced systemic resistance in plants

    E-Print Network [OSTI]

    Paré, Paul W.

    IN937a, with GB03 producing higher amounts of 3-methyl-1-butanol, 2-methyl-1-butanol and butane-1. All rights reserved. Keywords: Bacillus subtilis; B. amyliquefaciens; Ehrlich pathway; 3-Methyl-1-butanol; Plant growth promoting rhizobacteria (PGPR); Principal comp- onent analysis (PCA); Solid

  20. Energy Policy The university is committed to reducing its consumption of energy and promoting low carbon, energy

    E-Print Network [OSTI]

    Haase, Markus

    Energy Policy June 2009 The university is committed to reducing its consumption of energy and promoting low carbon, energy saving and energy efficiency initiatives as part of its Sustainable Development programme. Tackling climate change is one of our highest priorities and this reflects UK policy. Our Energy

  1. Program description The UPFellows program promoted by Universitat Pompeu Fabra (UPF, Barcelona, Spain) aims to offer career development

    E-Print Network [OSTI]

    Geffner, Hector

    Call Text Program description The UPFellows program promoted by Universitat Pompeu Fabra (UPF researchers of any nationality. UPF Fellows will join one of the most unique and dynamic research environments jointly by the Marie Curie COFUND program (7th Framework Program) and the UPF. Elegibility criteria

  2. OPET Organisations for the Promotion of Energy Technologies Contact: opet@tekes.fi www.tekes.fi/opet/

    E-Print Network [OSTI]

    has been focused on forest industry sites where large amounts of biomass is available. When residues. Project description Alholmens Kraft power plant introduces the "best-practise" biomass almost anywhere in Europe. ENERGIEENERGIE #12;OPET ­ Organisations for the Promotion of Energy

  3. Catalysis Letters Vol. 77, No. 4, 2001 197 Effects of Zn, Cu, and K promoters on the structure

    E-Print Network [OSTI]

    Iglesia, Enrique

    and on the reduction, carburization, and catalytic behavior of iron-based Fischer­Tropsch synthesis catalysts Senzi Li, and catalytic behavior of Fe­Zn and Fe oxides used as precursors to Fischer­Tropsch synthesis (FTS) catalysts­Zn oxide precursors. KEY WORDS: Fischer­Tropsch synthesis; promoters; iron; carbide; copper; potassium

  4. ANTI-APOPTOTIC FACTOR z-Val-Ala-Asp-FLUOROMETHYLKETONE PROMOTES THE SURVIVAL OF COCHLEAR HAIR CELLS IN A

    E-Print Network [OSTI]

    Avraham, Karen

    ANTI-APOPTOTIC FACTOR z-Val-Ala-Asp-FLUOROMETHYLKETONE PROMOTES THE SURVIVAL OF COCHLEAR HAIR CELLS- gin. A large effort is being made to protect hair cells from cell death after exposure to noise or drugs that can cause hearing loss. Our research focused on protecting hair cells from cell death

  5. Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth

    SciTech Connect (OSTI)

    Hsu, Ya-Yun [Department of Pharmacology, School of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan (China); Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan (China); Tseng, Yu-Ting [Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 80708, Taiwan (China); Lo, Yi-Ching, E-mail: yichlo@kmu.edu.tw [Department of Pharmacology, School of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan (China); Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan (China); Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 80708, Taiwan (China)

    2013-11-01T23:59:59.000Z

    Reactive oxygen intermediates production and apoptotic damage induced by high glucose are major causes of neuronal damage in diabetic neuropathy. Berberine (BBR), a natural antidiabetes drug with PI3K-activating activity, holds promise for diabetes because of its dual antioxidant and anti-apoptotic activities. We have previously reported that BBR attenuated H{sub 2}O{sub 2} neurotoxicity via activating the PI3K/Akt/Nrf2-dependent pathway. In this study, we further explored the novel protective mechanism of BBR on high glucose-induced apoptotic death and neurite damage of SH-SY5Y cells. Results indicated BBR (0.1–10 nM) significantly attenuated reactive oxygen species (ROS) production, nucleus condensation, and apoptotic death in high glucose-treated cells. However, AG1024, an inhibitor of insulin growth factor-1 (IGF-1) receptor, significantly abolished BBR protection against high glucose-induced neuronal death. BBR also increased Bcl-2 expression and decreased cytochrome c release. High glucose down-regulated IGF-1 receptor and phosphorylation of Akt and GSK-3?, the effects of which were attenuated by BBR treatment. BBR also activated nuclear erythroid 2-related factor 2 (Nrf2), the key antioxidative transcription factor, which is accompanied with up-regulation of hemeoxygenase-1 (HO-1). Furthermore, BBR markedly enhanced nerve growth factor (NGF) expression and promoted neurite outgrowth in high glucose-treated cells. To further determine the role of the Nrf2 in BBR neuroprotection, RNA interference directed against Nrf2 was used. Results indicated Nrf2 siRNA abolished BBR-induced HO-1, NGF, neurite outgrowth and ROS decrease. In conclusion, BBR attenuated high glucose-induced neurotoxicity, and we are the first to reveal this novel mechanism of BBR as an Nrf2 activator against glucose neurotoxicity, providing another potential therapeutic use of BBR on the treatment of diabetic complications. - Highlights: • BBR attenuates high glucose-induced ROS production and neuronal cell death. • BBR activates IGF-1/Akt/GSK-3? signaling under normal and high glucose conditions. • BBR enhances HO-1 and NGF expression through stimulating Nrf2 translocation. • BBR promotes neurite outgrowth through Nrf2-dependent pathway.

  6. Cloning of the human TASK-2 (KCNK5) promoter and its regulation by chronic hypoxia

    SciTech Connect (OSTI)

    Brazier, Stephen P. [School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3US (United Kingdom); Mason, Helen S. [School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3US (United Kingdom); Bateson, Alan N. [School of Biomedical Sciences, University of Leeds, Leeds LS2 9JT (United Kingdom); Kemp, Paul J. [School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3US (United Kingdom)]. E-mail: Kemp@cf.ac.uk

    2005-11-04T23:59:59.000Z

    The tandem P domain potassium channel family includes five members of the acid-sensing subfamily, TASK. TASK channels are active at resting potential and are inhibited by extracellular protons, suggesting they function as acid sensors and control excitability/ion homeostasis. Indeed, TASK-2 (KCNK5) has been shown to control excitability, volume regulation, bicarbonate handling, and apoptosis in a variety of tissues. With such diverse functions being ascribed to TASK-2, it is important to understand long-term as well as short-term regulation of this important channel. Thus, we have cloned the TASK-2 promoter, demonstrated that its transcriptional activity is dependent upon pO{sub 2}, shown that deletion of overlapping consensus binding sites for NF-{kappa}B/Elk-1 ablates this O{sub 2} sensitivity, and proved that Elk-1 binds preferentially to this site. Furthermore, the consequences of chronic hypoxia on natively expressed TASK-2 are decreased steady-state mRNA and cell depolarization showing that TASK-2 contributes to the excitability of this important lung cell type.

  7. Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4[alpha

    SciTech Connect (OSTI)

    Lu, Peng; Rha, Geun Bae; Melikishvili, Manana; Wu, Guangteng; Adkins, Brandon C.; Fried, Michael G.; Chi, Young-In (Kentucky)

    2010-11-09T23:59:59.000Z

    HNF4{alpha} (hepatocyte nuclear factor 4{alpha}) plays an essential role in the development and function of vertebrate organs, including hepatocytes and pancreatic {beta}-cells by regulating expression of multiple genes involved in organ development, nutrient transport, and diverse metabolic pathways. As such, HNF4{alpha} is a culprit gene product for a monogenic and dominantly inherited form of diabetes, known as maturity onset diabetes of the young (MODY). As a unique member of the nuclear receptor superfamily, HNF4{alpha} recognizes target genes containing two hexanucleotide direct repeat DNA-response elements separated by one base pair (DR1) by exclusively forming a cooperative homodimer. We describe here the 2.0 {angstrom} crystal structure of human HNF4{alpha} DNA binding domain in complex with a high affinity promoter element of another MODY gene, HNF1{alpha}, which reveals the molecular basis of unique target gene selection/recognition, DNA binding cooperativity, and dysfunction caused by diabetes-causing mutations. The predicted effects of MODY mutations have been tested by a set of biochemical and functional studies, which show that, in contrast to other MODY gene products, the subtle disruption of HNF4{alpha} molecular function can cause significant effects in afflicted MODY patients.

  8. The Structure of Neurexin 1[alpha] Reveals Features Promoting a Role as Synaptic Organizer

    SciTech Connect (OSTI)

    Chen, Fang; Venugopal, Vandavasi; Murray, Beverly; Rudenko, Gabby (Michigan)

    2014-10-02T23:59:59.000Z

    {alpha}-Neurexins are essential synaptic adhesion molecules implicated in autism spectrum disorder and schizophrenia. The {alpha}-neurexin extracellular domain consists of six LNS domains interspersed by three EGF-like repeats and interacts with many different proteins in the synaptic cleft. To understand how {alpha}-neurexins might function as synaptic organizers, we solved the structure of the neurexin 1{alpha} extracellular domain (n1{alpha}) to 2.65 {angstrom}. The L-shaped molecule can be divided into a flexible repeat I (LNS1-EGF-A-LNS2), a rigid horseshoe-shaped repeat II (LNS3-EGF-B-LNS4) with structural similarity to so-called reelin repeats, and an extended repeat III (LNS5-EGF-B-LNS6) with controlled flexibility. A 2.95 {angstrom} structure of n1{alpha} carrying splice insert SS3 in LNS4 reveals that SS3 protrudes as a loop and does not alter the rigid arrangement of repeat II. The global architecture imposed by conserved structural features enables {alpha}-neurexins to recruit and organize proteins in distinct and variable ways, influenced by splicing, thereby promoting synaptic function.

  9. Promoting the Market for Plug-in Hybrid and Battery Electric Vehicles: Role of Recharge Availability

    SciTech Connect (OSTI)

    Lin, Zhenhong [ORNL; Greene, David L [ORNL

    2012-01-01T23:59:59.000Z

    Much recent attention has been drawn to providing adequate recharge availability as a means to promote the battery electric vehicle (BEV) and plug-in hybrid electric vehicle (PHEV) market. The possible role of improved recharge availability in developing the BEV-PHEV market and the priorities that different charging options should receive from the government require better understanding. This study reviews the charging issue and conceptualizes it into three interactions between the charge network and the travel network. With travel data from 3,755 drivers in the National Household Travel Survey, this paper estimates the distribution among U.S. consumers of (a) PHEV fuel-saving benefits by different recharge availability improvements, (b) range anxiety by different BEV ranges, and (c) willingness to pay for workplace and public charging in addition to home recharging. With the Oak Ridge National Laboratory MA3T model, the impact of three recharge improvements is quantified by the resulting increase in BEV-PHEV sales. Compared with workplace and public recharging improvements, home recharging improvement appears to have a greater impact on BEV-PHEV sales. The impact of improved recharging availability is shown to be amplified by a faster reduction in battery cost.

  10. Effects of potential additives to promote seal swelling on the thermal stability of synthetic jet fuels

    SciTech Connect (OSTI)

    Lind, D.D.; Gormley, R.G.; Zandhuis, P.H.; Baltrus, J.P.

    2007-10-01T23:59:59.000Z

    Synthetic fuels derived from the Fischer-Tropsch (F-T) process using natural gas or coal-derived synthesis gas as feedstocks can be used for powering of ground vehicles, aircraft and ships. Because of their chemical and physical properties, F-T fuels will probably require additives in order to meet specifications with respect to lubricity and seal swell capability for use in ground and air vehicles. These additives can include oxygenates and compounds containing other heteroatoms that may adversely affect thermal stability. In order to understand what additives will be the most beneficial, a comprehensive experimental and computational study of conventional and additized fuels has been undertaken. The experimental approach includes analysis of the trace oxygenate and nitrogen-containing compounds present in conventional petroleum-derived fuels and trying to relate their presence (or absence) to changes in the desired properties of the fuels. This paper describes the results of efforts to test the thermal stability of synthetic fuels and surrogate fuels containing single-component additives that have been identified in earlier research as the best potential additives for promoting seal swelling in synthetic fuels, as well as mixtures of synthetic and petroleum-derived fuels.

  11. Collagen fibril surface displays a constellation of sites capable of promoting fibril assembly, stability, and hemostasis

    SciTech Connect (OSTI)

    Orgel, J.P.; Antipova, O.; Sagi, I.; Bitler, A.; Qiu, D.; Wang, R.; Xu, Y.; San Antonio, J.D. (IIT)

    2011-12-14T23:59:59.000Z

    Fibrillar collagens form the structural basis of organs and tissues including the vasculature, bone, and tendon. They are also dynamic, organizational scaffolds that present binding and recognition sites for ligands, cells, and platelets. We interpret recently published X-ray diffraction findings and use atomic force microscopy data to illustrate the significance of new insights into the functional organization of the collagen fibril. These data indicate that collagen's most crucial functional domains localize primarily to the overlap region, comprising a constellation of sites we call the 'master control region.' Moreover, the collagen's most exposed aspect contains its most stable part - the C-terminal region that controls collagen assembly, cross-linking, and blood clotting. Hidden beneath the fibril surface exists a constellation of 'cryptic' sequences poised to promote hemostasis and cell - collagen interactions in tissue injury and regeneration. These findings begin to address several important, and previously unresolved, questions: How functional domains are organized in the fibril, which domains are accessible, and which require proteolysis or structural trauma to become exposed? Here we speculate as to how collagen fibrillar organization impacts molecular processes relating to tissue growth, development, and repair.

  12. Myocardial Reloading after Extracorporeal Membrane Oxygenation Alters Substrate Metabolism While Promoting Protein Synthesis

    SciTech Connect (OSTI)

    Kajimoto, Masaki; Priddy, Colleen M.; Ledee, Dolena; Xu, Chun; Isern, Nancy G.; Olson, Aaron; Des Rosiers, Christine; Portman, Michael A.

    2013-08-19T23:59:59.000Z

    Extracorporeal membrane oxygenation (ECMO) unloads the heart providing a bridge to recovery in children after myocardial stunning. Mortality after ECMO remains high.Cardiac substrate and amino acid requirements upon weaning are unknown and may impact recovery. We assessed the hypothesis that ventricular reloading modulates both substrate entry into the citric acid cycle (CAC) and myocardial protein synthesis. Fourteen immature piglets (7.8-15.6 kg) were separated into 2 groups based on ventricular loading status: 8 hour-ECMO (UNLOAD) and post-wean from ECMO (RELOAD). We infused [2-13C]-pyruvate as an oxidative substrate and [13C6]-L-leucine, as a tracer of amino acid oxidation and protein synthesis into the coronary artery. RELOAD showed marked elevations in myocardial oxygen consumption above baseline and UNLOAD. Pyruvate uptake was markedly increased though RELOAD decreased pyruvate contribution to oxidative CAC metabolism.RELOAD also increased absolute concentrations of all CAC intermediates, while maintaining or increasing 13C-molar percent enrichment. RELOAD also significantly increased cardiac fractional protein synthesis rates by >70% over UNLOAD. Conclusions: RELOAD produced high energy metabolic requirement and rebound protein synthesis. Relative pyruvate decarboxylation decreased with RELOAD while promoting anaplerotic pyruvate carboxylation and amino acid incorporation into protein rather than to the CAC for oxidation. These perturbations may serve as therapeutic targets to improve contractile function after ECMO.

  13. How can environmental regulations promote clean coal technology adoption in APEC developing economies?

    SciTech Connect (OSTI)

    NONE

    2007-11-15T23:59:59.000Z

    The study examines both existing and emerging regulatory frameworks in order to determine which type of regulations that would be most effective at promoting clean coal technology adoption in development Asia Pacific Economic Co-operation (APEC) economies and would be practical to implement. regulations targeting air emissions; regulations targeting water use; and regulations concerning coal combustion by-products. When considering the potential effect of existing and new environmental regulations on the adoption of clean coal the analysis of technologies was organised into three categories: environmental control technologies; high efficiency coal combustion technologies; and carbon dioxide capture and storage (CCS). To target the recommendations towards APEC economies that would benefit the most from this analysis, the study focused on developing and transition APEC economies that are expected to rely on coal for a large part of their future generating capacity. These economies include China, Indonesia, the Philippines, the Russian Federation, Thailand, and Vietnam. ACARP provided funding to this study, under Project C15078. 10 figs., 14 tabs., 10 apps.

  14. Promotion effect of cobalt-based catalyst with rare earth for the ethanol steam reforming

    SciTech Connect (OSTI)

    Chiou, Josh Y. Z.; Chen, Ya-Ping; Yu, Shen-Wei; Wang, Chen-Bin [Department of Chemical and Materials Engineering, Chung Cheng Institute of Technology, National Defense University, Tahsi, Taoyuan 33509, Taiwan (China)

    2013-12-16T23:59:59.000Z

    Catalytic performance of ethanol steam reforming (ESR) was investigated on praseodymium (Pr) modified ceria-supported cobalt oxide catalyst. The ceria-supported cobalt oxide (Ce-Co) catalyst was prepared by co-precipitation-oxidation (CPO) method, and the doped Pr (5 and 10 wt% loading) catalysts (Pr{sub 5}?Ce?Co and Pr{sub 10}?Ce?Co) were prepared by incipient wetness impregnation method. The reduction pretreatment under 250 and 400 °C (H250 and H400) was also studied. All samples were characterized by XRD, TPR and TEM. Catalytic performance of ESR was tested from 250 to 500 °C in a fixed-bed reactor. The doping of Pr into the ceria lattice has significantly promoted the activity and reduced the coke formation. The products distribution also can be influenced by the different reduction pretreatment. The Pr{sub 10}?Ce?Co?H400 sample is a preferential ESR catalyst, where the hydrogen distribution approaches 73% at 475 °C with less amounts (< 2%) of CO and CH{sub 4}.

  15. Fuel cell assembly unit for promoting fluid service and electrical conductivity

    DOE Patents [OSTI]

    Jones, Daniel O. (Glenville, NY)

    1999-01-01T23:59:59.000Z

    Fluid service and/or electrical conductivity for a fuel cell assembly is promoted. Open-faced flow channel(s) are formed in a flow field plate face, and extend in the flow field plate face between entry and exit fluid manifolds. A resilient gas diffusion layer is located between the flow field plate face and a membrane electrode assembly, fluidly serviced with the open-faced flow channel(s). The resilient gas diffusion layer is restrained against entering the open-faced flow channel(s) under a compressive force applied to the fuel cell assembly. In particular, a first side of a support member abuts the flow field plate face, and a second side of the support member abuts the resilient gas diffusion layer. The support member is formed with a plurality of openings extending between the first and second sides of the support member. In addition, a clamping pressure is maintained for an interface between the resilient gas diffusion layer and a portion of the membrane electrode assembly. Preferably, the support member is spikeless and/or substantially flat. Further, the support member is formed with an electrical path for conducting current between the resilient gas diffusion layer and position(s) on the flow field plate face.

  16. Promoter sequence of 3-phosphoglycerate kinase gene 2 of lactic acid-producing fungus rhizopus oryzae and a method of expressing a gene of interest in fungal species

    DOE Patents [OSTI]

    Gao, Johnway [Richland, WA; Skeen, Rodney S [Pendleton, OR

    2003-03-04T23:59:59.000Z

    The present invention provides the promoter clone discovery of phosphoglycerate kinase gene 2 of a lactic acid-producing filamentous fungal strain, Rhizopus oryzae. The isolated promoter can constitutively regulate gene expression under various carbohydrate conditions. In addition, the present invention also provides a design of an integration vector for the transformation of a foreign gene in Rhizopus oryzae.

  17. Promoter sequence of 3-phosphoglycerate kinase gene 1 of lactic acid-producing fungus rhizopus oryzae and a method of expressing a gene of interest in fungal species

    DOE Patents [OSTI]

    Gao, Johnway [Richland, WA; Skeen, Rodney S [Pendleton, OR

    2002-10-15T23:59:59.000Z

    The present invention provides the promoter clone discovery of phosphoglycerate kinase gene 1 of a lactic acid-producing filamentous fungal strain, Rhizopus oryzae. The isolated promoter can constitutively regulate gene expression under various carbohydrate conditions. In addition, the present invention also provides a design of an integration vector for the transformation of a foreign gene in Rhizopus oryzae.

  18. Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in S. cerevisiae

    E-Print Network [OSTI]

    Church, George M.

    1 Genome-wide co-occurrence of promoter elements reveals a cis- regulatory cassette of r. We have conducted a genome-wide computational survey to identify cis-regulatory motif pairs that co-occur in a significantly high number of promoters in the S. cerevisiae genome. A pair of novel motifs, mRRPE and PAC, co

  19. On neutron star/supernova remnant associations

    E-Print Network [OSTI]

    V. V. Gvaramadze

    2001-04-01T23:59:59.000Z

    It is pointed out that a cavity supernova (SN) explosion of a moving massive star could result in a significant offset of the neutron star (NS) birth-place from the geometrical centre of the supernova remnant (SNR). Therefore: a) the high implied transverse velocities of a number of NSs (e.g. PSR B1610-50, PSR B1757-24, SGR0525-66) could be reduced; b) the proper motion vector of a NS should not necessarily point away from the geometrical centre of the associated SNR; c) the circle of possible NS/SNR associations could be enlarged. An observational test is discussed, which could allow to find the true birth-places of NSs associated with middle-aged SNRs, and thereby to get more reliable estimates of their transverse velocities.

  20. Microbial communities and greenhouse gas emissions associated with the biodegradation of specified risk material in compost

    SciTech Connect (OSTI)

    Xu, Shanwei [Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5 (Canada); Agriculture and Agri-Food Canada, Lethbridge Research Centre, P.O. Box 3000, Lethbridge, Alberta, Canada T1J 4B1 (Canada); Reuter, Tim [Alberta Agriculture and Rural Development, Lethbridge, Alberta, Canada T1J 4V6 (Canada); Gilroyed, Brandon H. [Agriculture and Agri-Food Canada, Lethbridge Research Centre, P.O. Box 3000, Lethbridge, Alberta, Canada T1J 4B1 (Canada); Tymensen, Lisa [Alberta Agriculture and Rural Development, Lethbridge, Alberta, Canada T1J 4V6 (Canada); Hao, Yongxin; Hao, Xiying [Agriculture and Agri-Food Canada, Lethbridge Research Centre, P.O. Box 3000, Lethbridge, Alberta, Canada T1J 4B1 (Canada); Belosevic, Miodrag [Department of Biological Science, University of Alberta, Edmonton, Alberta, Canada T6G 2E9 (Canada); Leonard, Jerry J. [Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5 (Canada); McAllister, Tim A., E-mail: tim.mcallister@agr.gc.ca [Agriculture and Agri-Food Canada, Lethbridge Research Centre, P.O. Box 3000, Lethbridge, Alberta, Canada T1J 4B1 (Canada)

    2013-06-15T23:59:59.000Z

    Highlights: ? Addition of feathers altered bacterial and fungal communities in compost. ? Microbial communities degrading SRM and compost matrix were distinct. ? Addition of feathers may enrich for microbial communities that degrade SRM. ? Inclusion of feather in compost increased both CH{sub 4} and N{sub 2}O emissions from compost. ? Density of methanogens and methanotrophs were weakly associated with CH{sub 4} emissions. - Abstract: Provided that infectious prions (PrP{sup Sc}) are inactivated, composting of specified risk material (SRM) may be a viable alternative to rendering and landfilling. In this study, bacterial and fungal communities as well as greenhouse gas emissions associated with the degradation of SRM were examined in laboratory composters over two 14 day composting cycles. Chicken feathers were mixed into compost to enrich for microbial communities involved in the degradation of keratin and other recalcitrant proteins such as prions. Feathers altered the composition of bacterial and fungal communities primarily during the first cycle. The bacterial genera Saccharomonospora, Thermobifida, Thermoactinomycetaceae, Thiohalospira, Pseudomonas, Actinomadura, and Enterobacter, and the fungal genera Dothideomycetes, Cladosporium, Chaetomium, and Trichaptum were identified as candidates involved in SRM degradation. Feathers increased (P < 0.05) headspace concentrations of CH{sub 4} primarily during the early stages of the first cycle and N{sub 2}O during the second. Although inclusion of feathers in compost increases greenhouse gas emissions, it may promote the establishment of microbial communities that are more adept at degrading SRM and recalcitrant proteins such as keratin and PrP{sup Sc}.

  1. Nowzari et al. Habitat Associations of Persian Wild Ass in Iran HABITAT ASSOCIATIONS OF PERSIAN WILD

    E-Print Network [OSTI]

    Rubenstein, Daniel I.

    25 Nowzari et al. · Habitat Associations of Persian Wild Ass in Iran HABITAT ASSOCIATIONS OF PERSIAN WILD ASS (EQUUS HEMIONUS ONAGER) IN QA- TROUYEH NATIONAL PARK, IRAN HANIYEH NOWZARI, Department of the IVth International Wildlife Management Congress: 25-30, 2013 Horses, zebras and asses, members

  2. MuseuM AssociAtes, inc. A 501(c)(3) not-For-Profit organization

    E-Print Network [OSTI]

    Missouri-Columbia, University of

    MuseuM AssociAtes, inc. A 501(c)(3) not-For-Profit organization in support of the Museum of Art on canvas (61.78) samuel H. Kress study collection (K1112) Printing provided by corporate sponsor ® MuseuM, May 3, 2014 For the benefit of the university of Missouri Museum of Art and Archaeology columbia

  3. Christopher M. Jones Staff Research Associate

    E-Print Network [OSTI]

    Kammen, Daniel M.

    Christopher M. Jones Staff Research Associate Renewable and Appropriate Energy Laboratory ­ 2005 M.S. Energy and Resources, University of California, Berkeley 2002 ­ 2005 M.A. Latin American, Berkeley Berkeley Graduate Student Instructor, Sociology 101 c. Selected Publications 1. Jones, C.M

  4. ISSUES AND ENVIRONMENTAL IMPACTS ASSOCIATED WITH

    E-Print Network [OSTI]

    CALIFORNIA ENERGY COMMISSION ISSUES AND ENVIRONMENTAL IMPACTS ASSOCIATED WITH ONCE-THROUGH COOLING AT CALIFORNIA'S COASTAL POWER PLANTS In Support of the 2005 Environmental Performance Report and 2005 Integrated Principal Authors Dr. Noel Davis, Chambers Group James Schoonmaker, Aspen Environmental Group Robert

  5. ISSUES AND ENVIRONMENTAL IMPACTS ASSOCIATED WITH

    E-Print Network [OSTI]

    CALIFORNIA ENERGY COMMISSION ISSUES AND ENVIRONMENTAL IMPACTS ASSOCIATED WITH ONCE-THROUGH COOLING of the Studies Used to Detect Impacts to Marine Environments by California's Coastal Power Plants Using Once of Assumptions, Methods, and Analyses Used In Recent Studies to Assess the Impacts of Power Plants That Use

  6. The Eurographics Association 2002. Efficient Rendering of

    E-Print Network [OSTI]

    Heidrich, Wolfgang

    © The Eurographics Association 2002. Efficient Rendering of Spatial Bi-directional Reflectance general surface appearance representation. We describe a method for rendering such surfaces rapidly-painted surfaces. We also propose a method of rendering such spatial bi-directional reflectance distribution

  7. Original article Blue-stain fungi associated

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Original article Blue-stain fungi associated with Tomicus piniperda in Sweden and preliminary to determine the development of blue-staining of sapwood. Fungi were isolated from samples of inner bark and blue-stained sapwood in connection with galleries of T piniperda. Samples were also taken from beetle

  8. Using Associations Aspects to Implement Organisational Contracts

    E-Print Network [OSTI]

    Han, Jun

    can be viewed as a system that, in part, coordinates the respiratory, circulatory, and digestive that Association-aspects were a suitable mechanism for implementing a coordination system. In this paper we show systems in dynamic environments. In many living systems this organisation is, in part, achieved through

  9. LIFE Power Plant Fusion Power Associates

    E-Print Network [OSTI]

    LIFE Power Plant Fusion Power Associates December 14, 2011 Mike Dunne LLNL #12;NIf-1111-23714.ppt LIFE power plant 2 #12;LIFE delivery timescale NIf-1111-23714.ppt 3 #12;Timely delivery is enabled dpa) § Removes ion threat and mitigates x-ray threat ­ allows simple steel piping § No need

  10. Business Development Associate -1493 Job Description

    E-Print Network [OSTI]

    Evans, Paul G.

    Business Development Associate - 1493 Job Description: BioTechnique is a contract manufacturing our Business Development efforts. This will offer a start-up environment, with hands-on opportunities with business development in our consulting, software and investments departments. These new graduates

  11. IGOR KOPYLOV Associate Professor of Economics

    E-Print Network [OSTI]

    Loudon, Catherine

    IGOR KOPYLOV Associate Professor of Economics University of California, Irvine SSPA 3177, Social · Visiting Lecturer, New Economic School, Moscow, spring 2002 EDUCATION · University of Rochester, Ph.D. in Economics, October 2003 Thesis: 'Essays on Subjective Probability, Risk, and Ambiguity', supervised by L

  12. ASSOCIATED LABORATORY PLASMA PHYSICS AND ENGINEERING

    E-Print Network [OSTI]

    Lisboa, Universidade Técnica de

    ASSOCIATED LABORATORY ON PLASMA PHYSICS AND ENGINEERING Centro de Fusão Nuclear Centro de Física dos PlasmasCentro de Fusão Nuclear INSTITUTO SUPERIOR TÉCNICO Centro de Física dos Plasmas WORK Units of excellence in Europe, in the fields of Nuclear Fusion, Plasma Physics and Technologies

  13. LE CONTRLE EXTERNE DES ASSOCIATIONS PAR LES

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , which can be used equally to evaluate public policies, - an external control through new rules of accountancy of the public subsidies, This article shows that the management control can influence financial to internal users like managers. Mots clés. - Secteur public, contrôle externe, association, gestion

  14. Oge Marques, PhD Associate Professor

    E-Print Network [OSTI]

    Marques, Oge

    Science COLLEGE OF ENGINEERING & COMPUTER SCIENCE 777 Glades Road, Boca Raton, FL 33431 tel: 561 Background · PhD in Computer Engineering, Florida Atlantic University, Boca Raton, FL (USA), Aug. 2001), Feb. 1987. 2. Employment History Associate Chairman ­ Dept of Computer and Electrical Engineering

  15. Oge Marques, PhD Associate Professor

    E-Print Network [OSTI]

    Marques, Oge

    Science COLLEGE OF ENGINEERING & COMPUTER SCIENCE 777 Glades Road, Boca Raton, FL 33431 tel: 561 Background · PhD in Computer Engineering, Florida Atlantic University, Boca Raton, FL (USA), Aug. 2001), Feb. 1987. 2. Employment History Associate Professor ­ Dept of Computer and Electrical Engineering

  16. Oge Marques, Ph.D. Associate Professor

    E-Print Network [OSTI]

    Marques, Oge

    Science COLLEGE OF ENGINEERING & COMPUTER SCIENCE 777 Glades Road, Boca Raton, FL 33431 tel: 561 · Ph.D. in Computer Engineering, Florida Atlantic University, Boca Raton, FL (USA), Aug. 2001. · Master Tecnológica Federal do Paraná - UTFPR) Curitiba-PR (Brazil), Feb. 1987. 2. Employment History Associate

  17. Oge Marques, Ph.D. Associate Professor

    E-Print Network [OSTI]

    Marques, Oge

    Science COLLEGE OF ENGINEERING & COMPUTER SCIENCE 777 Glades Road, Boca Raton, FL 33431 tel: 561 Background · Ph.D. in Computer Engineering, Florida Atlantic University, Boca Raton, FL (USA), Aug. 2001), Feb. 1987. 2. Employment History Associate Chairman Dept of Computer and Electrical Engineering

  18. Oklahoma Sheriffs' Association Ok ahoma Sheriff

    E-Print Network [OSTI]

    Harms, Kyle E.

    Oklahoma Sheriffs' Association Ok ahoma Sheriff The Official Magazine for Oklahoma Sher iffs was recently developed by the Oklahoma Office of Homeland Security (OKOHS), Oklahoma Council on Law Enforcement the current credentialing system already implemented in the state of Oklahoma. In addition to obtaining

  19. Polynomial over Associative D-Algebra

    E-Print Network [OSTI]

    Aleks Kleyn

    2015-04-12T23:59:59.000Z

    In the paper I considered algebra of polynomials over associative D-algebra with unit. Using the tensor notation allows to simplify the representation of polynomial. I considered questions related to divisibility of polynomial of any power over polynomial of power 1.

  20. Quadratic Equation over Associative D-Algebra

    E-Print Network [OSTI]

    Aleks Kleyn

    2015-05-30T23:59:59.000Z

    In this paper, I treat quadratic equation over associative $D$-algebra. In quaternion algebra $H$, the equation $x^2=a$ has either $2$ roots, or infinitely many roots. Since $a\\in R$, $aalgebra, the equation $$(x-b)(x-a)+(x-a)(x-c)=0$$ $b\

  1. LAMELLAR MAGNETISM ASSOCIATED WITH NANOSCALE EXSOLUTION

    E-Print Network [OSTI]

    Dunin-Borkowski, Rafal E.

    LAMELLAR MAGNETISM ASSOCIATED WITH NANOSCALE EXSOLUTION IN THE ILMENITE-HEMATITE SOLID SOLUTION-hematite (FeTiO3-Fe2O3) solid solution is one of the most important magnetic phases in nature. Unusual magnetic, magnetic ordering, and exsolution. This presentation describes how this interaction leads to the phenomenon

  2. Nico Larco, AIA Associate Professor of Architecture

    E-Print Network [OSTI]

    Nico Larco, AIA Associate Professor of Architecture Affiliated Faculty, Department of Planning, Public Policy, and Management Co-Founder and Co-Director, Sustainable Cities Initiative University of Oregon EDUCATION University of California, Berkeley Master of Architecture, 2001 Master of City Planning

  3. Jump to first page American Planning Association

    E-Print Network [OSTI]

    to first page How Smart is your Community? Small group exercise 5. CENTRAL CITY VITALITY Examples: GradeJump to first page American Planning Association Core Smart Growth Principles 1) INCREASED CITIZEN, adaptive re-use) 5) CENTRAL CITY VITALITY 6) GREATER MIX OF USES AND HOUSING CHOICES FOCUSED AROUND HUMAN

  4. How to Associate Propositional Proof Systems

    E-Print Network [OSTI]

    Cook, Stephen A.

    : Proof system f p-simulates proof system g if 9 polytime T such that f(T(x)) = g(x) GentzenHow to Associate Propositional Proof Systems and Theories with Complexity Classes Part III; Introduction to Propositional Proof Com- plexity A proof system is a polynomial time map f : f0; 1g #3; onto

  5. 5 Examination of Persistence Associated with Coupling

    E-Print Network [OSTI]

    Bhatt, Uma

    -1), in which the MLM is forced with heat and momentum fluxes from the fully coupled simulation. The examination94 5 Examination of Persistence Associated with Coupling The results of Chapter 4 suggest on mechanisms that act to increase the persistence of climate variability in the coupled system. The vertical

  6. Alaska Native Village CEO Association 2015 Conference

    Broader source: Energy.gov [DOE]

    The Alaska Native Village Corporation Association is hosting its 7th Annual 2015 Conference in Anchorage, Alaska. The two-day conference includes a State of Alaska update, board election best practices, Alaska's economic future, Alaska Native subsistence co-management, and more.

  7. Friendly LandscapingTM Community Associations

    E-Print Network [OSTI]

    Jawitz, James W.

    and Property Managers. Then schedule a free FYN Neighborhood Recognition visit with a Master Gardener FYN programs are open to all persons without regard to race, color, creed, sex, age, handicap or nationalFlorida Friendly LandscapingTM for Community Associations Workshop Landscape Best Management

  8. Friendly LandscapingTM Community Associations

    E-Print Network [OSTI]

    Jawitz, James W.

    and Property Managers. Then schedule a free FYN Neighborhood Recognition visit with a Master Gardener FYN. Extension programs are open to all persons without regard to race, color, creed, sex, age, handicapFlorida Friendly LandscapingTM for Community Associations Workshop Landscape Best Management

  9. Friendly LandscapingTM Community Associations

    E-Print Network [OSTI]

    Watson, Craig A.

    members, Lakes and Landscape Committees and Property Managers. Then schedule a free FYN Neighborhood. Extension programs are open to all persons without regard to race, color, creed, sex, age, handicapFlorida Friendly LandscapingTM for Community Associations Workshop Landscape Best Management

  10. TOP 10 VULNERABILITIES OF CONTROL SYSTEMS AND THEIR ASSOCIATED...

    Energy Savers [EERE]

    TOP 10 VULNERABILITIES OF CONTROL SYSTEMS AND THEIR ASSOCIATED MITIGATIONS TOP 10 VULNERABILITIES OF CONTROL SYSTEMS AND THEIR ASSOCIATED MITIGATIONS This document provides...

  11. Top 10 Vulnerabilities of Control Systems and Their Associated...

    Energy Savers [EERE]

    Top 10 Vulnerabilities of Control Systems and Their Associated Migitations (2006) Top 10 Vulnerabilities of Control Systems and Their Associated Migitations (2006) This document...

  12. 2015 Iowa Wind Power Conference and Iowa Wind Energy Association...

    Energy Savers [EERE]

    2015 Iowa Wind Power Conference and Iowa Wind Energy Association Midwest Regional Energy Job Fair 2015 Iowa Wind Power Conference and Iowa Wind Energy Association Midwest Regional...

  13. NA MB - Associate Administrator for Management & Budget | National...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics NA MB - Associate Administrator for Management ... NA MB - Associate Administrator...

  14. NA APM - Associate Administrator for Acquisition & Project Management...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics NA APM - Associate Administrator for Acquisition ... NA APM - Associate...

  15. NA 40 - Associate Administrator for Emergency Operations | National...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics NA 40 - Associate Administrator for Emergency Operations NA 40 - Associate...

  16. NA 80 - Associate Administrator for Counterterrorism andCounterprolif...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics NA 80 - Associate Administrator for Counterterrorism ... NA 80 - Associate...

  17. NA 50 - Associate Administrator for Safety, Infrastructure and...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics NA 50 - Associate Administrator for Safety, ... NA 50 - Associate Administrator...

  18. NA 70 - Associate Administrator for Defense Nuclear Security...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics NA 70 - Associate Administrator for Defense ... NA 70 - Associate Administrator...

  19. Department of Energy Cites Brookhaven Science Associates, LLC...

    Energy Savers [EERE]

    Brookhaven Science Associates, LLC for Worker Safety and Health Violations Department of Energy Cites Brookhaven Science Associates, LLC for Worker Safety and Health Violations...

  20. South Mississippi Electric Power Association Smart Grid Project (Mississippi)

    Broader source: Energy.gov [DOE]

    South Mississippi Electric Power Association’s (SMEPA) smart grid project involves the deployment of advanced metering infrastructure (AMI) and covers the Generation and Transmission (G&T)...

  1. Comments by the Energy Storage Association to the Department...

    Energy Savers [EERE]

    by the Energy Storage Association to the Department of Energy Electricity Advisory Council - March 13, 2014 Comments by the Energy Storage Association to the Department of Energy...

  2. Bioenergy Technologies Office: Association of Fish and Wildlife...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office: Association of Fish and Wildlife Agencies Agricultural Conservation Committee Meeting Bioenergy Technologies Office: Association of Fish and Wildlife Agencies Agricultural...

  3. Tennessee Veterans Business Association 3rd Annual Business and...

    Broader source: Energy.gov (indexed) [DOE]

    Tennessee Veterans Business Association 3rd Annual Business and Education Showcase Tennessee Veterans Business Association 3rd Annual Business and Education Showcase January 28,...

  4. Biomineralization Associated with Microbial Reduction of Fe3...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Associated with Microbial Reduction of Fe3+ and Oxidation of Fe2+ in Solid Minerals . Biomineralization Associated with Microbial Reduction of Fe3+ and Oxidation of Fe2+...

  5. Intercalation of Trichloroethene by Sediment-Associated Clay...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Intercalation of Trichloroethene by Sediment-Associated Clay Minerals. Intercalation of Trichloroethene by Sediment-Associated Clay Minerals. Abstract: The objective of this...

  6. ORISE: Worker Health Studies - Beryllium Associated Worker Registry...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Oak Ridge Institute for Science Education Beryllium Associated Worker Registry (BAWR) The Oak Ridge Institute for Science and Education (ORISE) maintains the Beryllium Associated...

  7. Quantifying Cradle-to-Farm Gate Life Cycle Impacts Associated...

    Energy Savers [EERE]

    Life Cycle Impacts Associated with Fertilizer used for Corn, Soybean, and Stover Production Quantifying Cradle-to-Farm Gate Life Cycle Impacts Associated with Fertilizer used...

  8. Protocol for Addressing Induced Seismicity Associated with Enhanced...

    Office of Environmental Management (EM)

    Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems This...

  9. Geothermal Energy Association Honors NREL's Dr. Bharathan for...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Association Honors NREL's Dr. Bharathan for Work in Condenser Technology Geothermal Energy Association Honors NREL's Dr. Bharathan for Work in Condenser Technology July 16, 2012 -...

  10. ORNL's Peng wins Fusion Power Associates Leadership Award | ornl...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Peng Wins Leadership Award ORNL's Peng wins Fusion Power Associates Leadership Award Morgan McCorkle - August 17, 2010 ORNL's Martin Peng, recipient of Fusion Power Associates'...

  11. american planning association: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Page Topic Index 1 Associate at the American Planning Association. Planning for Solar Energy CiteSeer Summary: There is a growing desire among communities to become more...

  12. Identification of a putative protein profile associating with...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a putative protein profile associating with tamoxifen therapy resistance in breast cancer. Identification of a putative protein profile associating with tamoxifen therapy...

  13. Substrate Changes Associated with the Chemistry of Self-Assembled...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Substrate Changes Associated with the Chemistry of Self-Assembled Monolayers on Silicon. Substrate Changes Associated with the Chemistry of Self-Assembled Monolayers on Silicon....

  14. associative memory models: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David 1971-01-01 2 COMPLEX ASSOCIATIVE MEMORY NEURAL NETWORK MODEL FOR INVARIANT PATTERN RECOGNITION Engineering Websites Summary: COMPLEX ASSOCIATIVE MEMORY NEURAL...

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    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David 1971-01-01 2 COMPLEX ASSOCIATIVE MEMORY NEURAL NETWORK MODEL FOR INVARIANT PATTERN RECOGNITION Engineering Websites Summary: COMPLEX ASSOCIATIVE MEMORY NEURAL...

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    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

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    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Platelet Proteome Changes Associated with Diabetes and During Platelet Storage for Transfusion. Platelet Proteome Changes Associated with Diabetes and During Platelet Storage for...

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    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    smith@sfu.ca Adam Holbrook, Associate Director jholbrooCarthy Roman Onufrijchuk Richard Smith David Zandvliet RESEARCHERS & ASSOCIATES Nancy Duxbury Gordon Gow communications...

  19. Glosten Associates Tests Innovative High-Strength Mooring Lines...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Glosten Associates Tests Innovative High-Strength Mooring Lines for Deepwater Offshore Wind Installations Glosten Associates Tests Innovative High-Strength Mooring Lines for...

  20. DOE Awards $3 Million Contract to Oak Ridge Associated Universities...

    Office of Environmental Management (EM)

    Million Contract to Oak Ridge Associated Universities for Expert Review of Yucca Mountain Work DOE Awards 3 Million Contract to Oak Ridge Associated Universities for Expert...

  1. ASSOCIATED RESIDENTIAL COMMUNITY HOUSING (ARCH) PROGRAM UC San Diego's Associated Residential Community Housing (ARCH) is committed to supporting the academic

    E-Print Network [OSTI]

    California at San Diego, University of

    ASSOCIATED RESIDENTIAL COMMUNITY HOUSING (ARCH) PROGRAM I. MISSION UC San Diego's Associated Residential Community Housing (ARCH) is committed to supporting the academic mission of the university, Associated Residential Community Housing (ARCH) offers campus housing to graduate and professional students

  2. Identification of protein binding sites in the promoter regions of a light-responsive gene family in a cyanobacterium

    E-Print Network [OSTI]

    Mueller, Ulrich Wolfgang

    1991-01-01T23:59:59.000Z

    binding sites were characterized that display some interdependence for protein binding ability. One binding site was identified as the primary sequence required for protein binding to the second site. Mutations were introduced into the first binding...lment of the requirements for the degree of MASTER OF SCIENCE December 1991 Major Subject: Biology ZDIBlTZPZCATION OP PROTEIN BINDINQ SITES IN TEB PROMOTER REGIONS OP A LIGHT RESPONSIVE SBBB FAMILY IN A CYANOBACTBRZUM A Thesis by ULRICH WOLFGANG...

  3. Activation and promotion studies in a mixed slurry reactor with an iron-manganese Fischer-Tropsch catalyst

    SciTech Connect (OSTI)

    Pennline, H.W.; Zarochak, M.F.; Stencel, J.M.; Diehl, J.R.

    1987-03-01T23:59:59.000Z

    Synthesis gas was reacted over a coprecipitated iron-manganese Fischer-Tropsch catalyst in a slurry reactor. The effect of various activation parameters - temperature, pressure, and gas composition - on subsequent catalyst activity and product selectivity was investigated. The gas composition had the most dramatic effect on the catalyst activation and the ensuing synthesis gas conversion. The effect of potassium promotion on catalyst activity and product selectivity was also studied in slurry reactor tests.

  4. Interactions of hydrogen with alkali promoted Ru/SiO{sub 2} catalysts: A proton NMR study

    SciTech Connect (OSTI)

    Ozbay, U.D.

    1994-05-10T23:59:59.000Z

    Role of H spillover to the silica support was studied using chemisorption; a strongly bound component of spilled over H was found in the silica support which interfered with accurate measurements of active metal sites via volumetric strong H chemisorption. The volumetric chemisorption technique was modified so that measurement times were reduced from 12--36 h to 1 h. The active Ru surface was characterized means of changes in proton spin counts and NMR Knight shifts vs alkali loading. Na, K blocked the active surface of Ru metal, but Cs was pushed off by H chemisorption. The alkali promoters restricted H mobility on both metal surface and at the metal support interfaces; this is consistent with effects on Fischer-Tropsch synthesis. {sup 1}H NMR was used to study the effect of the active metal and promoter on support hydroxyl groups. The OH group density in the silica support decreased with metal and/or promoter loading, but not on a one-to-one basis; the exchange efficiency of the hydroxyls decreased with atomic size of the alkali metal. An additional downfield proton resonance was detected which was assigned to the alkali hydroxide species in the support.

  5. Studies on gene expression profiling in JB6 cells susceptible and resistant to tumor promoter induced neoplastic transformation and regulation of gene expression at the AP-1 DNA binding site

    E-Print Network [OSTI]

    Samuel, Shaija

    2005-11-01T23:59:59.000Z

    and resistance to tumor promoter induced neoplastic transformation, we analyzed the gene expression profile differences among tumor promoter TPA treated and untreated mouse epidermal JB6 cells by means of cDNA microarray analyses. The expression patterns...

  6. Extended emission associated with young HII regions

    E-Print Network [OSTI]

    S. P. Ellingsen; S. S. Shabala; S. E. Kurtz

    2004-12-06T23:59:59.000Z

    We have used the Australia Telescope Compact Array (ATCA) to make observations of a sample of eight young ultra-compact HII regions, selected on the basis that they have associated class II methanol maser emission. We have made observations sensitive to both compact and extended structures and find both to be present in most sources. The scale of the extended emission in our sample is in general less than that observed towards samples based on IRAS properties, or large single-dish flux densities. Our observations are consistent with a scenario where extended and compact radio continuum emission coexists within HII regions for a significant period of time. We suggest that these observations are consistent with a model where HII evolution takes place within hierarchically structured molecular clouds. This model is the subject of a companion paper (Shabala et al. 2005) and addresses both the association between compact and extended emission and UCHII region lifetime problem.

  7. Anaphylatoxin C5a fails to promote prostacyclin release from cultured human endothelial cells

    SciTech Connect (OSTI)

    Lunberg, C.; Marceau, F.; Huey, R.; Hugli, T.E.

    1986-03-01T23:59:59.000Z

    A predominantly relaxing effect of C5a on isolated blood vessels has been reported, which is associated with prostacyclin release from the vessel wall. Further, the well known hypothensive effect of C5a, also associated with increased prostacyclin output and preventable by indomethacin, indicates an involvement of endothelial cells in this reaction. In this study the authors characterized the response to C5a of cultured human endothelial cells from umbilical vein as measured by prostacyclin release. Prostacyclin was quantitated by radioimmunoassay as 6-keto-PGF/sub 1..cap alpha../. Subcultured cells respond to histamine and mellitin with increased prostacyclin production, but do not respond to leukotriene C4 (LTC/sub 4/). Primary cultures, on the other hand, respond to LTC/sub 4/ and the histamine response is 7-fold greater for these cells than for subcultured cells. However, neither primary nor subcultured cells release prostacyclin following application of either human C5a (100 nM) or C3a (1 ..mu..M). Also, these cells fail to show specific binding sites for /sup 125/I-C5a. In contrast, endothelial cells in the presence of human PMNs challenged with C5a release prostacyclin. These data suggest that C5a has no direct effect on the endothelial cell, but rather activates this cell indirectly via mediators from other cells known to respond to C5a.

  8. The usage of trisiloxanes is common as adjuvants in pesticide formulation to assist with the delivery of agrochemicals to a spray mixture. The unique ability of trisiloxane superspreaders to promote rapid

    E-Print Network [OSTI]

    Haller-Dintelmann, Robert

    with the delivery of agrochemicals to a spray mixture. The unique ability of trisiloxane superspreaders to promote

  9. Lithium Depletion of Nearby Young Stellar Associations

    E-Print Network [OSTI]

    Erin Mentuch; Alexis Brandeker; Marten H. van Kerkwijk; Ray Jayawardhana; Peter H. Hauschildt

    2008-08-26T23:59:59.000Z

    We estimate cluster ages from lithium depletion in five pre-main-sequence groups found within 100 pc of the Sun: TW Hydrae Association, Eta Chamaeleontis Cluster, Beta Pictoris Moving Group, Tucanae-Horologium Association and AB Doradus Moving Group. We determine surface gravities, effective temperatures and lithium abundances for over 900 spectra through least squares fitting to model-atmosphere spectra. For each group, we compare the dependence of lithium abundance on temperature with isochrones from pre-main-sequence evolutionary tracks to obtain model dependent ages. We find that the Eta Chamaelontis Cluster and the TW Hydrae Association are the youngest, with ages of 12+/-6 Myr and 12+/-8 Myr, respectively, followed by the Beta Pictoris Moving Group at 21+/-9 Myr, the Tucanae-Horologium Association at 27+/-11 Myr, and the AB Doradus Moving Group at an age of at least 45 Myr (where we can only set a lower limit since the models -- unlike real stars -- do not show much lithium depletion beyond this age). Here, the ordering is robust, but the precise ages depend on our choice of both atmospheric and evolutionary models. As a result, while our ages are consistent with estimates based on Hertzsprung-Russell isochrone fitting and dynamical expansion, they are not yet more precise. Our observations do show that with improved models, much stronger constraints should be feasible: the intrinsic uncertainties, as measured from the scatter between measurements from different spectra of the same star, are very low: around 10 K in effective temperature, 0.05 dex in surface gravity, and 0.03 dex in lithium abundance.

  10. Induced seismicity associated with enhanced geothermal system

    SciTech Connect (OSTI)

    Majer, Ernest; Majer, Ernest L.; Baria, Roy; Stark, Mitch; Oates, Stephen; Bommer, Julian; Smith, Bill; Asanuma, Hiroshi

    2006-09-26T23:59:59.000Z

    Enhanced Geothermal Systems (EGS) offer the potential to significantly add to the world energy inventory. As with any development of new technology, some aspects of the technology has been accepted by the general public, but some have not yet been accepted and await further clarification before such acceptance is possible. One of the issues associated with EGS is the role of microseismicity during the creation of the underground reservoir and the subsequent extraction of the energy. The primary objectives of this white paper are to present an up-to-date review of the state of knowledge about induced seismicity during the creation and operation of enhanced geothermal systems, and to point out the gaps in knowledge that if addressed will allow an improved understanding of the mechanisms generating the events as well as serve as a basis to develop successful protocols for monitoring and addressing community issues associated with such induced seismicity. The information was collected though literature searches as well as convening three workshops to gather information from a wide audience. Although microseismicity has been associated with the development of production and injection operations in a variety of geothermal regions, there have been no or few adverse physical effects on the operations or on surrounding communities. Still, there is public concern over the possible amount and magnitude of the seismicity associated with current and future EGS operations. It is pointed out that microseismicity has been successfully dealt with in a variety of non-geothermal as well as geothermal environments. Several case histories are also presented to illustrate a variety of technical and public acceptance issues. It is concluded that EGS Induced seismicity need not pose any threat to the development of geothermal resources if community issues are properly handled. In fact, induced seismicity provides benefits because it can be used as a monitoring tool to understand the effectiveness of the EGS operations and shed light on the mechanics of the reservoir.

  11. Energy Balance and Emissions Associated with Biochar

    E-Print Network [OSTI]

    Lehmann, Johannes

    to produce biochar for land application, the energy produced per unit energy input at 2­7 MJ/MJ is greaterEnergy Balance and Emissions Associated with Biochar Sequestration and Pyrolysis Bioenergy Production J O H N L . G A U N T * , , A N D J O H A N N E S L E H M A N N College of Agriculture and Life

  12. QER- Comment of Natural Gas Supply Association

    Broader source: Energy.gov [DOE]

    TO: Quadrennial Energy Review Task Force In response to the Department of Energy’s August 25, 2014 Federal Register Notice seeking input on the Quadrennial Energy Review, attached are comments from the Natural Gas Supply Association. Thank you for this opportunity to share our views on the important issue of energy infrastructure. If we can be of further assistance, please let me know. Regards,

  13. 2004 Reversible Associations in Structure & Molecular Biology

    SciTech Connect (OSTI)

    Edward Eisenstein Nancy Ryan Gray

    2005-03-23T23:59:59.000Z

    The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

  14. Associate Professor of Anthropology Project Title: Global Philanthropic Networks

    E-Print Network [OSTI]

    Saldin, Dilano

    INGRID JORDT Associate Professor of Anthropology Project Title: The Power of People-to- People Networks

  15. Fusion Power Associates, 2011 Annual Meeting 1 General Fusion

    E-Print Network [OSTI]

    7 Plasma Injector 10 people $3M 1 year #12;Fusion Power Associates, 2011 Annual Meeting 8 Density people $3.5M 14 months #12;Fusion Power Associates, 2011 Annual Meeting 11 Plasma Compression ExperimentsFusion Power Associates, 2011 Annual Meeting 1 General Fusion #12;Fusion Power Associates, 2011

  16. Mining Positive and Negative Association Rules from Large Databases

    E-Print Network [OSTI]

    Gent, Universiteit

    Mining Positive and Negative Association Rules from Large Databases Chris Cornelis Dept. Appl. Math. Keywords--association rules, data mining, Apriori I. INTRODUCTION The idea of association rule (AR) mining a D-link network card". Mining negative association rules, however, raises a number of critical issues

  17. COMM-OPINION-ORDER, 76 FERC 61,347, Promoting Wholesale Competition Through Open-Access Non-discriminatory Transmission Services by Public Utilities, Docket No. RM95-8-000, Recovery of Stranded Costs by

    E-Print Network [OSTI]

    Laughlin, Robert B.

    COMM-OPINION-ORDER, 76 FERC ¶61,347, Promoting Wholesale Competition Through Open-Access Non Incorporated Promoting Wholesale Competition Through Open-Access Non-discriminatory Transmission Services Utilities, Docket No. RM94-7-001 [62,646] [¶61,347] Promoting Wholesale Competition Through Open-Access Non

  18. Targeted deletion of Kif18a protects from colitis-associated colorectal (CAC) tumors in mice through impairing Akt phosphorylation

    SciTech Connect (OSTI)

    Zhu, Houbao [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China)] [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China); Xu, Wangyang [Department of Clinical Laboratories, Ninth People’s Hospital, SJTUSM, Shanghai 200011 (China)] [Department of Clinical Laboratories, Ninth People’s Hospital, SJTUSM, Shanghai 200011 (China); Zhang, Hongxin [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China)] [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China); Liu, Jianbing [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China) [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China); Shanghai Research Center for Model Organisms, Shanghai 201203 (China); Xu, Haimin [Department of Pathology, Rui-Jin Hospital, SJTUSM, Shanghai 200025 (China)] [Department of Pathology, Rui-Jin Hospital, SJTUSM, Shanghai 200025 (China); Lu, Shunyuan; Dang, Suying [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China)] [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China); Kuang, Ying [Shanghai Research Center for Model Organisms, Shanghai 201203 (China)] [Shanghai Research Center for Model Organisms, Shanghai 201203 (China); Jin, Xiaolong [Department of Pathology, Rui-Jin Hospital, SJTUSM, Shanghai 200025 (China)] [Department of Pathology, Rui-Jin Hospital, SJTUSM, Shanghai 200025 (China); Wang, Zhugang, E-mail: zhugangw@shsmu.edu.cn [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China) [State Key Laboratory of Medical Genomics, Research Center for Experimental Medicine, Rui-Jin Hospital and Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai 200025 (China); Shanghai Research Center for Model Organisms, Shanghai 201203 (China)

    2013-08-16T23:59:59.000Z

    Highlights: •Kif18A is up-regulated in CAC of mouse model. •Kif18a{sup ?/?} mice are protected from CAC. •Tumor cells from Kif18a{sup ?/?} mice undergo more apoptosis. •Kif18A deficiency induces poor Atk phosphorylation. -- Abstract: Kinesins are a superfamily of molecular motors involved in cell division or intracellular transport. They are becoming important targets for chemotherapeutic intervention of cancer due to their crucial role in mitosis. Here, we demonstrate that the kinesin-8 Kif18a is overexpressed in murine CAC and is a crucial promoter during early CAC carcinogenesis. Kif18a-deficient mice are evidently protected from AOM–DSS-induced colon carcinogenesis. Kif18A is responsible for proliferation of colonic tumor cells, while Kif18a ablation in mice promotes cell apoptosis. Mechanistically, Kif18a is responsible for induction of Akt phosphorylation, which is known to be associated with cell survival regulation. In conclusion, Kif18a is critical for colorectal carcinogenesis in the setting of inflammation by mechanisms of increased PI3K-AKT signaling. Inhibition of Kif18A activity may be useful in the prevention or chemotherapeutic intervention of CAC.

  19. Kinesin Motor Transport is Altered by Macromolecular Crowding and Transiently Associated Microtubule-Associated Proteins

    E-Print Network [OSTI]

    Leslie Conway; Jennifer L. Ross

    2014-09-11T23:59:59.000Z

    Intracellular transport of vesicular cargos, organelles, and other macromolecules is an essential process to move large items through a crowded, and inhomogeneous cellular environment. In an effort to dissect the fundamental effects of crowding and an increasingly complex cellular environment on the transport of individual motor proteins, we have performed in vitro reconstitution experiments with single kinesin-1 motors walking on microtubules in the presence of crowding agents and transient microtubule-associated proteins that more closely emulate the cellular environment. Macromolecular crowding due to inert polymers caused enhanced run lengths of motors, but displayed an increased tendency for non-specific motor association and diffusion, most likely due to depletion interactions. We found that transiently bound associated proteins slowed forward motion, but did not drastically affect the association times, in opposition to previously reported obstacle properties of stably associated microtubule-associated proteins, such as the neuronal protein tau. Such studies of the transport properties of molecular motors in increasingly complex reconstituted environments are important to illuminate the fundamental biophysical principles underlying the essential process of intracellular cargo transport.

  20. Sponsors of CIEEDAC: Natural Resources Canada, Canadian Industry Program for Energy Conservation, Aluminium Industry Association, Canadian Petroleum Products Institute, Canadian Portland Cement Association, Canadian Pulp

    E-Print Network [OSTI]

    , Aluminium Industry Association, Canadian Petroleum Products Institute, Canadian Portland Cement Association